HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 340 404 7.4E-19 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 SUPERFAMILY SSF52540 97 304 2.24E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 Gene3D G3DSA:3.40.50.300 95 261 5.4E-37 T 14-10-2018 HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 Pfam PF00308 Bacterial dnaA protein 97 312 3.4E-56 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 428 22.789 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 427 1.8E-103 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 Gene3D G3DSA:3.30.300.180 3 74 7.4E-13 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 227 254 9.7E-22 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 129 149 9.7E-22 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 193 207 9.7E-22 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 387 406 9.7E-22 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 160 174 9.7E-22 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 Gene3D G3DSA:1.10.8.60 262 330 2.4E-13 T 14-10-2018 HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 SMART SM00382 128 260 3.2E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 Pfam PF11638 DnaA N-terminal domain 5 61 5.2E-13 T 14-10-2018 IPR024633 DnaA N-terminal domain HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 Gene3D G3DSA:1.10.1750.10 331 430 1.7E-22 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 SMART SM00760 338 406 1.1E-17 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HL41_02270 b248d6ee0498f367fb1259d39db345f2 448 SUPERFAMILY SSF48295 336 427 1.73E-21 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HL41_03905 7df3d373206462ee582b9dcb244c0757 901 SUPERFAMILY SSF53335 71 610 2.03E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_03905 7df3d373206462ee582b9dcb244c0757 901 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 510 516 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HL41_03905 7df3d373206462ee582b9dcb244c0757 901 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 95 154 1.4E-4 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 HL41_03905 7df3d373206462ee582b9dcb244c0757 901 Pfam PF06634 Protein of unknown function (DUF1156) 12 66 3.6E-23 T 14-10-2018 IPR009537 Domain of unknown function DUF1156 HL41_01575 18171c33f46ee6e83c9a264b15f3aa54 209 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HL41_01575 18171c33f46ee6e83c9a264b15f3aa54 209 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 90 1.8E-14 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HL41_01575 18171c33f46ee6e83c9a264b15f3aa54 209 Gene3D G3DSA:1.20.120.1760 5 201 6.5E-34 T 14-10-2018 HL41_05325 5ad7decc07306543add7b5f179d0bdea 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05325 5ad7decc07306543add7b5f179d0bdea 37 SUPERFAMILY SSF57840 1 37 3.4E-15 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05325 5ad7decc07306543add7b5f179d0bdea 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.688 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05325 5ad7decc07306543add7b5f179d0bdea 37 Pfam PF00444 Ribosomal protein L36 1 37 4.1E-17 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05325 5ad7decc07306543add7b5f179d0bdea 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.1E-21 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_02110 ddc91d346ebf9b739519e027e18393c8 247 Pfam PF01493 GXGXG motif 21 186 8.6E-39 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 HL41_02110 ddc91d346ebf9b739519e027e18393c8 247 PIRSF PIRSF006519 1 247 4.3E-81 T 14-10-2018 IPR012061 Glutamate synthase, large subunit domain 3 stand-alone protein HL41_02110 ddc91d346ebf9b739519e027e18393c8 247 Gene3D G3DSA:2.160.20.60 11 242 4.4E-38 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 HL41_02110 ddc91d346ebf9b739519e027e18393c8 247 SUPERFAMILY SSF69336 6 245 7.98E-56 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 HL41_07830 a00a17edc9360ca03522bcba295dc680 347 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 36 341 1.1E-113 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 HL41_07830 a00a17edc9360ca03522bcba295dc680 347 Gene3D G3DSA:3.40.190.10 110 286 1.5E-117 T 14-10-2018 HL41_07830 a00a17edc9360ca03522bcba295dc680 347 Pfam PF12849 PBP superfamily domain 35 313 1.4E-58 T 14-10-2018 IPR024370 PBP domain HL41_07830 a00a17edc9360ca03522bcba295dc680 347 PIRSF PIRSF002756 15 346 2.9E-109 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 HL41_07830 a00a17edc9360ca03522bcba295dc680 347 Gene3D G3DSA:3.40.190.10 37 331 1.5E-117 T 14-10-2018 HL41_07830 a00a17edc9360ca03522bcba295dc680 347 SUPERFAMILY SSF53850 36 343 3.01E-96 T 14-10-2018 HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 SUPERFAMILY SSF51735 1 177 4.87E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 Gene3D G3DSA:3.40.50.720 4 330 9.7E-122 T 14-10-2018 HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 315 2.7E-20 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 338 39.673 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 SUPERFAMILY SSF55347 150 312 4.47E-50 T 14-10-2018 HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 343 4.6E-123 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 Gene3D G3DSA:3.30.360.10 148 312 9.7E-122 T 14-10-2018 HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 141 1.3E-31 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HL41_05620 8c7eaf3fc303873f61201b08db41a5a0 344 SMART SM00859 3 142 2.7E-39 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 Pfam PF01966 HD domain 350 441 6.9E-20 T 14-10-2018 IPR006674 HD domain HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 TIGRFAM TIGR00277 HDIG: HDIG domain 346 423 9.3E-25 T 14-10-2018 IPR006675 HDIG domain HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 SMART SM00322 222 289 7.4E-8 T 14-10-2018 IPR004087 K Homology domain GO:0003676 HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 Gene3D G3DSA:3.30.1370.10 221 318 4.6E-8 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 Gene3D G3DSA:1.10.3210.10 332 509 9.0E-24 T 14-10-2018 HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 SMART SM00471 346 452 1.5E-12 T 14-10-2018 IPR003607 HD/PDEase domain HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 18 534 8.9E-206 T 14-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 SUPERFAMILY SSF54791 222 309 4.18E-15 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 Pfam PF12072 Domain of unknown function (DUF3552) 29 216 5.9E-31 T 14-10-2018 IPR022711 Ribonuclease Y, N-terminal HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 SUPERFAMILY SSF109604 328 484 2.92E-32 T 14-10-2018 HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 Hamap MF_00335 Ribonuclease Y [rny]. 1 534 24.145 T 14-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HL41_01520 deca05c25c13f11dcbfedf1fdf1e24c2 534 Pfam PF00013 KH domain 227 281 2.4E-5 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 HL41_08440 383569931ca70fa8137b0736510c167c 502 Pfam PF04055 Radical SAM superfamily 113 266 1.4E-8 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_08440 383569931ca70fa8137b0736510c167c 502 TIGRFAM TIGR03955 rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG 29 502 5.8E-140 T 14-10-2018 IPR024007 [FeFe]-hydrogenase maturation HydG, radical SAM HL41_08440 383569931ca70fa8137b0736510c167c 502 SMART SM00876 299 410 8.3E-28 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HL41_08440 383569931ca70fa8137b0736510c167c 502 SUPERFAMILY SSF102114 67 358 7.32E-49 T 14-10-2018 HL41_08440 383569931ca70fa8137b0736510c167c 502 Gene3D G3DSA:3.20.20.70 37 421 2.4E-119 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_08440 383569931ca70fa8137b0736510c167c 502 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 299 408 2.3E-19 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 552 5.8E-170 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 SUPERFAMILY SSF109604 339 490 2.64E-9 T 14-10-2018 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 Pfam PF05746 DALR anticodon binding domain 584 683 1.6E-9 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 6.6E-28 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 6.6E-28 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 245 260 6.6E-28 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 317 333 6.6E-28 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 395 414 6.6E-28 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 690 22.195 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00860 8a01a62072d0f9b7d2eaf81dc70e198b 691 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 689 8.6E-181 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_03405 8390d989ea135c638942399cc089f85f 146 Gene3D G3DSA:2.70.40.10 1 143 6.1E-40 T 14-10-2018 IPR036157 dUTPase-like superfamily HL41_03405 8390d989ea135c638942399cc089f85f 146 TIGRFAM TIGR00576 dut: dUTP diphosphatase 3 143 1.3E-31 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 HL41_03405 8390d989ea135c638942399cc089f85f 146 SUPERFAMILY SSF51283 2 143 2.36E-34 T 14-10-2018 IPR036157 dUTPase-like superfamily HL41_03405 8390d989ea135c638942399cc089f85f 146 Pfam PF00692 dUTPase 11 143 9.1E-24 T 14-10-2018 IPR029054 dUTPase-like HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 Pfam PF03471 Transporter associated domain 194 266 4.0E-15 T 14-10-2018 IPR005170 Transporter-associated domain HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 SMART SM00116 71 120 4.0 T 14-10-2018 IPR000644 CBS domain HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 SMART SM00116 133 181 0.31 T 14-10-2018 IPR000644 CBS domain HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 Gene3D G3DSA:3.30.465.10 189 266 5.8E-16 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 SUPERFAMILY SSF56176 192 268 2.18E-16 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 Pfam PF00571 CBS domain 68 118 0.0035 T 14-10-2018 IPR000644 CBS domain HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 Pfam PF00571 CBS domain 132 180 1.8E-5 T 14-10-2018 IPR000644 CBS domain HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 SUPERFAMILY SSF54631 51 181 2.4E-22 T 14-10-2018 HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 Gene3D G3DSA:3.10.580.10 43 185 2.4E-29 T 14-10-2018 HL41_02930 05e1b42f8e4bcb8bd2391fbe48c68f5a 273 SMART SM01091 189 267 6.1E-16 T 14-10-2018 IPR005170 Transporter-associated domain HL41_06655 5bdc7b8c378814834fafbf1f8d913d30 318 Gene3D G3DSA:1.20.58.340 130 254 2.9E-26 T 14-10-2018 HL41_06655 5bdc7b8c378814834fafbf1f8d913d30 318 Gene3D G3DSA:1.20.58.340 256 318 3.4E-7 T 14-10-2018 HL41_06655 5bdc7b8c378814834fafbf1f8d913d30 318 SUPERFAMILY SSF144083 248 315 2.75E-10 T 14-10-2018 HL41_06655 5bdc7b8c378814834fafbf1f8d913d30 318 Gene3D G3DSA:3.30.460.20 13 125 8.8E-22 T 14-10-2018 HL41_06655 5bdc7b8c378814834fafbf1f8d913d30 318 SUPERFAMILY SSF143865 21 247 2.22E-48 T 14-10-2018 HL41_06655 5bdc7b8c378814834fafbf1f8d913d30 318 Pfam PF01544 CorA-like Mg2+ transporter protein 22 314 1.2E-53 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 HL41_04600 433b3bb824f65884f8a061d421a16f67 330 SUPERFAMILY SSF52540 21 296 1.68E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04600 433b3bb824f65884f8a061d421a16f67 330 Pfam PF02562 PhoH-like protein 118 321 6.3E-96 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 HL41_04600 433b3bb824f65884f8a061d421a16f67 330 Gene3D G3DSA:3.40.50.300 115 321 4.5E-76 T 14-10-2018 HL41_01725 48b23cc9571f47746100272cddb5e49c 373 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 10 370 4.9E-143 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HL41_01725 48b23cc9571f47746100272cddb5e49c 373 Gene3D G3DSA:3.20.20.105 1 373 1.0E-156 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HL41_01725 48b23cc9571f47746100272cddb5e49c 373 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 2 368 51.557 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HL41_01725 48b23cc9571f47746100272cddb5e49c 373 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 10 370 3.1E-150 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HL41_01725 48b23cc9571f47746100272cddb5e49c 373 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 364 3.4E-81 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HL41_01725 48b23cc9571f47746100272cddb5e49c 373 SUPERFAMILY SSF51713 1 367 1.05E-143 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HL41_09035 1d5999eed50d7df10bfb830e1fd3590b 148 Pfam PF01467 Cytidylyltransferase-like 18 111 8.7E-18 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HL41_09035 1d5999eed50d7df10bfb830e1fd3590b 148 Gene3D G3DSA:3.40.50.620 2 148 2.0E-43 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_09035 1d5999eed50d7df10bfb830e1fd3590b 148 SUPERFAMILY SSF52374 14 143 2.58E-25 T 14-10-2018 HL41_09035 1d5999eed50d7df10bfb830e1fd3590b 148 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 16 79 5.9E-16 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HL41_09035 1d5999eed50d7df10bfb830e1fd3590b 148 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 5 146 4.1E-63 T 14-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 HL41_08275 b17dd9f8a6276ac017096828ca162ded 307 Gene3D G3DSA:3.40.50.620 167 305 3.4E-24 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_08275 b17dd9f8a6276ac017096828ca162ded 307 Gene3D G3DSA:3.40.50.620 3 160 4.1E-23 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_08275 b17dd9f8a6276ac017096828ca162ded 307 SUPERFAMILY SSF52402 6 152 2.6E-18 T 14-10-2018 HL41_08275 b17dd9f8a6276ac017096828ca162ded 307 SUPERFAMILY SSF52402 169 300 2.85E-21 T 14-10-2018 HL41_08275 b17dd9f8a6276ac017096828ca162ded 307 PRINTS PR01438 Universal stress protein signature 265 277 2.2E-9 T 14-10-2018 IPR006015 Universal stress protein A HL41_08275 b17dd9f8a6276ac017096828ca162ded 307 PRINTS PR01438 Universal stress protein signature 283 305 2.2E-9 T 14-10-2018 IPR006015 Universal stress protein A HL41_08275 b17dd9f8a6276ac017096828ca162ded 307 PRINTS PR01438 Universal stress protein signature 167 185 2.2E-9 T 14-10-2018 IPR006015 Universal stress protein A HL41_08275 b17dd9f8a6276ac017096828ca162ded 307 Pfam PF00582 Universal stress protein family 170 302 2.0E-19 T 14-10-2018 IPR006016 UspA HL41_08275 b17dd9f8a6276ac017096828ca162ded 307 Pfam PF00582 Universal stress protein family 7 150 2.4E-14 T 14-10-2018 IPR006016 UspA HL41_04615 affbbfc310616de7b99a8052277bc209 488 SMART SM00267 319 488 1.5E-52 T 14-10-2018 IPR000160 GGDEF domain HL41_04615 affbbfc310616de7b99a8052277bc209 488 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 326 486 1.2E-49 T 14-10-2018 IPR000160 GGDEF domain HL41_04615 affbbfc310616de7b99a8052277bc209 488 Gene3D G3DSA:3.30.70.270 321 486 1.3E-50 T 14-10-2018 HL41_04615 affbbfc310616de7b99a8052277bc209 488 Pfam PF00990 Diguanylate cyclase, GGDEF domain 333 484 7.3E-43 T 14-10-2018 IPR000160 GGDEF domain HL41_04615 affbbfc310616de7b99a8052277bc209 488 Gene3D G3DSA:3.40.50.2300 189 320 1.4E-27 T 14-10-2018 HL41_04615 affbbfc310616de7b99a8052277bc209 488 Gene3D G3DSA:3.40.50.2300 61 188 7.4E-16 T 14-10-2018 HL41_04615 affbbfc310616de7b99a8052277bc209 488 SMART SM00448 192 306 7.3E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_04615 affbbfc310616de7b99a8052277bc209 488 SMART SM00448 64 178 1.4E-7 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_04615 affbbfc310616de7b99a8052277bc209 488 Pfam PF00072 Response regulator receiver domain 194 303 3.0E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_04615 affbbfc310616de7b99a8052277bc209 488 Pfam PF00072 Response regulator receiver domain 75 177 1.0E-9 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_04615 affbbfc310616de7b99a8052277bc209 488 SUPERFAMILY SSF52172 193 328 5.69E-28 T 14-10-2018 IPR011006 CheY-like superfamily HL41_04615 affbbfc310616de7b99a8052277bc209 488 SUPERFAMILY SSF52172 58 185 4.7E-16 T 14-10-2018 IPR011006 CheY-like superfamily HL41_04615 affbbfc310616de7b99a8052277bc209 488 SUPERFAMILY SSF55073 335 487 7.69E-43 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 Gene3D G3DSA:3.40.440.10 5 259 4.7E-104 T 14-10-2018 HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 Gene3D G3DSA:1.10.300.10 102 200 4.7E-104 T 14-10-2018 HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 208.211 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 SMART SM00788 3 423 9.1E-287 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 SUPERFAMILY SSF52540 1 422 7.22E-177 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 428 2.5E-176 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 Pfam PF00709 Adenylosuccinate synthetase 5 420 7.1E-189 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 Gene3D G3DSA:3.90.170.10 266 430 4.0E-73 T 14-10-2018 HL41_03080 cf30b1b9d52aaa0fcc7cc98fd114fa78 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 14-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 527 538 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 Gene3D G3DSA:3.30.70.20 519 579 2.7E-10 T 14-10-2018 HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 Gene3D G3DSA:3.50.50.60 372 432 9.0E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 156 275 7.1E-14 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 177 1.5E-8 T 14-10-2018 HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 471 478 1.5E-8 T 14-10-2018 HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 431 1.5E-8 T 14-10-2018 HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 175 3.8E-6 T 14-10-2018 HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 416 432 3.8E-6 T 14-10-2018 HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 557 568 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 SUPERFAMILY SSF54862 519 591 3.41E-15 T 14-10-2018 HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 Pfam PF13187 4Fe-4S dicluster domain 527 572 5.4E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 Gene3D G3DSA:3.50.50.60 433 494 9.0E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 SUPERFAMILY SSF51905 137 499 1.53E-28 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 Gene3D G3DSA:3.50.50.60 150 287 3.2E-19 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08930 6886d54ad48db8a7e34fb2ff7d638114 733 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 602 726 1.9E-36 T 14-10-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 HL41_03755 ac0441a276b4c30ab0b89a79414b101e 252 Gene3D G3DSA:3.30.420.40 4 244 5.1E-69 T 14-10-2018 HL41_03755 ac0441a276b4c30ab0b89a79414b101e 252 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 51 245 4.1E-49 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 HL41_03755 ac0441a276b4c30ab0b89a79414b101e 252 SUPERFAMILY SSF53067 3 244 4.26E-39 T 14-10-2018 HL41_03755 ac0441a276b4c30ab0b89a79414b101e 252 Gene3D G3DSA:3.30.420.40 89 229 5.1E-69 T 14-10-2018 HL41_03755 ac0441a276b4c30ab0b89a79414b101e 252 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 243 3.2E-67 T 14-10-2018 IPR008275 CoA enzyme activase HL41_05390 65f1b471bc3ea4347484de68c1301372 98 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 94 9.8E-35 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05390 65f1b471bc3ea4347484de68c1301372 98 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 88 17.322 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05390 65f1b471bc3ea4347484de68c1301372 98 SUPERFAMILY SSF50104 1 93 2.78E-33 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily HL41_05390 65f1b471bc3ea4347484de68c1301372 98 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 31 94 4.8E-28 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05390 65f1b471bc3ea4347484de68c1301372 98 Pfam PF00467 KOW motif 1 29 1.6E-6 T 14-10-2018 IPR005824 KOW HL41_05390 65f1b471bc3ea4347484de68c1301372 98 Gene3D G3DSA:2.30.30.30 1 93 7.5E-38 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 404 421 4.5E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 421 441 4.5E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 SUPERFAMILY SSF46689 350 440 2.27E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 161 174 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 Gene3D G3DSA:3.40.50.300 123 307 2.9E-69 T 14-10-2018 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 223 238 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 350 359 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 SUPERFAMILY SSF52540 136 380 1.95E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 SMART SM00382 157 300 2.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 SMART SM00448 3 114 8.6E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 Pfam PF00158 Sigma-54 interaction domain 137 303 1.1E-70 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 Gene3D G3DSA:3.40.50.2300 4 122 1.5E-35 T 14-10-2018 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 SUPERFAMILY SSF52172 3 182 6.97E-44 T 14-10-2018 IPR011006 CheY-like superfamily HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 Gene3D G3DSA:1.10.10.60 375 442 2.5E-18 T 14-10-2018 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 Pfam PF00072 Response regulator receiver domain 5 114 1.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 Pfam PF02954 Bacterial regulatory protein, Fis family 400 436 3.3E-15 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_08735 e11e306a0ddc0a8bfbcac90edef0a930 453 Gene3D G3DSA:1.10.8.60 308 374 5.3E-28 T 14-10-2018 HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 Pfam PF00226 DnaJ domain 4 66 5.0E-32 T 14-10-2018 IPR001623 DnaJ domain HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 SUPERFAMILY SSF49493 212 297 1.31E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 Gene3D G3DSA:2.60.260.20 207 303 5.8E-21 T 14-10-2018 HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 Pfam PF01556 DnaJ C terminal domain 145 286 5.4E-20 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 SUPERFAMILY SSF46565 3 103 3.14E-34 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 SMART SM00271 3 61 1.6E-37 T 14-10-2018 IPR001623 DnaJ domain HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 PRINTS PR00625 DnaJ domain signature 61 80 8.0E-30 T 14-10-2018 IPR001623 DnaJ domain HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 PRINTS PR00625 DnaJ domain signature 6 24 8.0E-30 T 14-10-2018 IPR001623 DnaJ domain HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 PRINTS PR00625 DnaJ domain signature 24 39 8.0E-30 T 14-10-2018 IPR001623 DnaJ domain HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 PRINTS PR00625 DnaJ domain signature 41 61 8.0E-30 T 14-10-2018 IPR001623 DnaJ domain HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 Gene3D G3DSA:1.10.287.110 1 136 1.3E-36 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 14-10-2018 IPR018253 DnaJ domain, conserved site HL41_05510 4079deb3fae3ca34583ee4db1883078b 305 Gene3D G3DSA:2.60.260.20 143 200 1.3E-9 T 14-10-2018 HL41_03190 4547bce4e0f1ae67545e9cfa2dace794 399 Gene3D G3DSA:2.40.420.20 40 393 1.3E-77 T 14-10-2018 HL41_03190 4547bce4e0f1ae67545e9cfa2dace794 399 SUPERFAMILY SSF111369 190 272 1.44E-8 T 14-10-2018 HL41_03190 4547bce4e0f1ae67545e9cfa2dace794 399 Gene3D G3DSA:2.40.50.100 57 255 1.3E-77 T 14-10-2018 HL41_03190 4547bce4e0f1ae67545e9cfa2dace794 399 Gene3D G3DSA:1.10.287.470 91 218 1.3E-77 T 14-10-2018 HL41_03190 4547bce4e0f1ae67545e9cfa2dace794 399 SUPERFAMILY SSF111369 57 126 1.26E-6 T 14-10-2018 HL41_03190 4547bce4e0f1ae67545e9cfa2dace794 399 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 191 393 1.8E-34 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 HL41_03190 4547bce4e0f1ae67545e9cfa2dace794 399 Gene3D G3DSA:2.40.30.170 44 335 1.3E-77 T 14-10-2018 HL41_03190 4547bce4e0f1ae67545e9cfa2dace794 399 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 44 299 1.4E-24 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HL41_07935 33dbed26cdcffb0b6eb32cdddb163f6e 514 SMART SM00382 20 267 0.0011 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_07935 33dbed26cdcffb0b6eb32cdddb163f6e 514 SUPERFAMILY SSF52540 4 206 4.71E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07935 33dbed26cdcffb0b6eb32cdddb163f6e 514 SUPERFAMILY SSF52540 129 427 8.85E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07935 33dbed26cdcffb0b6eb32cdddb163f6e 514 Gene3D G3DSA:3.40.50.300 5 166 5.6E-33 T 14-10-2018 HL41_07935 33dbed26cdcffb0b6eb32cdddb163f6e 514 Pfam PF05970 PIF1-like helicase 17 212 3.6E-33 T 14-10-2018 IPR010285 DNA helicase Pif1-like GO:0000723|GO:0003678|GO:0006281 HL41_07935 33dbed26cdcffb0b6eb32cdddb163f6e 514 Gene3D G3DSA:3.40.50.300 332 400 2.2E-6 T 14-10-2018 HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 SUPERFAMILY SSF82697 84 157 1.33E-7 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Gene3D G3DSA:3.30.1330.10 626 841 8.5E-45 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Pfam PF02769 AIR synthase related protein, C-terminal domain 448 593 1.5E-23 T 14-10-2018 IPR010918 PurM-like, C-terminal domain HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Pfam PF02769 AIR synthase related protein, C-terminal domain 853 993 1.2E-17 T 14-10-2018 IPR010918 PurM-like, C-terminal domain HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 SUPERFAMILY SSF109736 182 258 2.48E-12 T 14-10-2018 HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Gene3D G3DSA:3.90.650.10 847 1022 9.7E-41 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 89 156 5.4E-5 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 SUPERFAMILY SSF55326 638 845 1.96E-47 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Gene3D G3DSA:3.30.1330.10 249 434 3.1E-50 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 SUPERFAMILY SSF82697 2 72 2.79E-5 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Gene3D G3DSA:3.90.650.10 436 620 2.8E-54 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 SUPERFAMILY SSF56042 445 665 3.29E-50 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Gene3D G3DSA:3.30.1280.10 84 163 6.0E-5 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 SUPERFAMILY SSF55326 237 433 6.13E-39 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 SUPERFAMILY SSF56042 849 1021 1.5E-39 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Pfam PF00586 AIR synthase related protein, N-terminal domain 319 430 7.6E-11 T 14-10-2018 IPR016188 PurM-like, N-terminal domain HL41_03655 0d6b3113949bc678f188178bf22886e7 1022 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 175 1022 206.386 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 Gene3D G3DSA:2.170.280.10 178 414 2.6E-96 T 14-10-2018 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 142 2.6E-28 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 Gene3D G3DSA:2.30.220.10 190 285 2.6E-96 T 14-10-2018 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 SUPERFAMILY SSF64518 1 507 3.53E-71 T 14-10-2018 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 Pfam PF07196 Flagellin hook IN motif 266 319 1.4E-8 T 14-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 Gene3D G3DSA:1.20.1330.10 45 466 2.6E-96 T 14-10-2018 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 PRINTS PR00207 Flagellin signature 76 95 1.4E-9 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 PRINTS PR00207 Flagellin signature 37 54 1.4E-9 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 PRINTS PR00207 Flagellin signature 111 134 1.4E-9 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 Gene3D G3DSA:1.20.58.1830 5 506 2.6E-96 T 14-10-2018 HL41_01740 a6c77059a165071e99c4d7d48f353797 507 Pfam PF00700 Bacterial flagellin C-terminal helical region 424 506 2.4E-17 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PIRSF PIRSF004557 4 435 3.5E-120 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 20 38 1.3E-86 T 14-10-2018 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 1.3E-86 T 14-10-2018 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 271 290 1.3E-86 T 14-10-2018 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 1.3E-86 T 14-10-2018 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 1.3E-86 T 14-10-2018 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 153 178 1.3E-86 T 14-10-2018 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 179 202 1.3E-86 T 14-10-2018 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 1.3E-86 T 14-10-2018 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 1.3E-86 T 14-10-2018 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 Gene3D G3DSA:1.10.3370.10 5 424 3.3E-159 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 17 424 5.4E-120 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 Hamap MF_01465 Protein translocase subunit SecY [secY]. 7 428 29.102 T 14-10-2018 IPR026593 Protein translocase subunit SecY HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 Pfam PF00344 SecY translocase 73 412 6.8E-115 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HL41_05345 adc67c2f5505b744d2e4f4e9ae6bb5be 436 SUPERFAMILY SSF103491 7 419 2.22E-124 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HL41_04765 e131d8e7f1d023a5341ec8e81a7c8830 260 Pfam PF02195 ParB-like nuclease domain 34 91 6.4E-11 T 14-10-2018 IPR003115 ParB/Sulfiredoxin HL41_04765 e131d8e7f1d023a5341ec8e81a7c8830 260 SMART SM00470 19 103 8.4E-4 T 14-10-2018 IPR003115 ParB/Sulfiredoxin HL41_04765 e131d8e7f1d023a5341ec8e81a7c8830 260 Gene3D G3DSA:3.90.1530.10 10 100 1.6E-7 T 14-10-2018 HL41_04765 e131d8e7f1d023a5341ec8e81a7c8830 260 SUPERFAMILY SSF110849 20 94 1.44E-13 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily HL41_05720 1cde5fe7314e18ffedc779a867639f9f 207 Pfam PF13424 Tetratricopeptide repeat 106 178 3.3E-11 T 14-10-2018 HL41_05720 1cde5fe7314e18ffedc779a867639f9f 207 Pfam PF13181 Tetratricopeptide repeat 70 96 0.19 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05720 1cde5fe7314e18ffedc779a867639f9f 207 SMART SM00028 107 140 68.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05720 1cde5fe7314e18ffedc779a867639f9f 207 SMART SM00028 67 100 0.35 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05720 1cde5fe7314e18ffedc779a867639f9f 207 SMART SM00028 147 180 0.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05720 1cde5fe7314e18ffedc779a867639f9f 207 SUPERFAMILY SSF48452 47 188 1.71E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_05720 1cde5fe7314e18ffedc779a867639f9f 207 Gene3D G3DSA:1.25.40.10 37 207 5.2E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 199 224 2.1E-66 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 38 64 2.1E-66 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 230 250 2.1E-66 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 118 141 2.1E-66 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 9 25 2.1E-66 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 252 272 2.1E-66 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 276 302 2.1E-66 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 1 334 1.2E-96 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 SUPERFAMILY SSF48029 118 328 2.62E-66 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 Pfam PF01706 FliG C-terminal domain 222 328 5.5E-41 T 14-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 Gene3D G3DSA:1.10.220.30 199 336 2.6E-47 T 14-10-2018 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 Gene3D G3DSA:1.10.220.30 93 196 5.8E-31 T 14-10-2018 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 PIRSF PIRSF003161 3 336 1.1E-116 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 Gene3D G3DSA:1.10.220.30 1 89 3.1E-19 T 14-10-2018 HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 SUPERFAMILY SSF48029 9 121 1.41E-15 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 Pfam PF14841 FliG middle domain 119 191 3.8E-27 T 14-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain HL41_00550 ed850bb2ec03c8b6335fb6a29cacecf7 336 Pfam PF14842 FliG N-terminal domain 8 108 1.2E-22 T 14-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain HL41_06065 53606f8b9a3c78da8858d8eeb20f6d51 191 Gene3D G3DSA:1.20.1260.10 1 146 5.4E-58 T 14-10-2018 IPR012347 Ferritin-like HL41_06065 53606f8b9a3c78da8858d8eeb20f6d51 191 Gene3D G3DSA:2.20.28.10 147 191 1.4E-19 T 14-10-2018 HL41_06065 53606f8b9a3c78da8858d8eeb20f6d51 191 SUPERFAMILY SSF57802 149 190 1.81E-11 T 14-10-2018 HL41_06065 53606f8b9a3c78da8858d8eeb20f6d51 191 SUPERFAMILY SSF47240 4 147 2.48E-38 T 14-10-2018 IPR009078 Ferritin-like superfamily HL41_06065 53606f8b9a3c78da8858d8eeb20f6d51 191 Pfam PF02915 Rubrerythrin 12 138 7.9E-30 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HL41_04935 f38cb265d724e57ca44feb2bdbad2280 346 Pfam PF04055 Radical SAM superfamily 106 274 1.1E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_04935 f38cb265d724e57ca44feb2bdbad2280 346 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 2 342 5.9E-131 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 HL41_04935 f38cb265d724e57ca44feb2bdbad2280 346 SUPERFAMILY SSF102114 101 319 1.83E-17 T 14-10-2018 HL41_04935 f38cb265d724e57ca44feb2bdbad2280 346 PIRSF PIRSF006004 2 345 1.2E-133 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 HL41_04935 f38cb265d724e57ca44feb2bdbad2280 346 Gene3D G3DSA:1.10.150.530 3 63 5.5E-20 T 14-10-2018 HL41_04935 f38cb265d724e57ca44feb2bdbad2280 346 Pfam PF13394 4Fe-4S single cluster domain 111 204 1.2E-4 T 14-10-2018 HL41_04935 f38cb265d724e57ca44feb2bdbad2280 346 Gene3D G3DSA:3.20.20.70 65 330 2.3E-104 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_04935 f38cb265d724e57ca44feb2bdbad2280 346 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 3 346 70.218 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 Pfam PF00140 Sigma-70 factor, region 1.2 43 73 2.2E-6 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 Gene3D G3DSA:1.10.601.10 41 349 2.8E-68 T 14-10-2018 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 SUPERFAMILY SSF88659 350 424 4.8E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 Gene3D G3DSA:1.10.10.10 428 511 3.3E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 275 499 2.0E-36 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 Gene3D G3DSA:1.10.10.10 350 426 9.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 SUPERFAMILY SSF88946 60 344 1.2E-45 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 PRINTS PR00046 Major sigma-70 factor signature 486 497 1.1E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 PRINTS PR00046 Major sigma-70 factor signature 450 462 1.1E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 PRINTS PR00046 Major sigma-70 factor signature 301 314 1.1E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 PRINTS PR00046 Major sigma-70 factor signature 325 333 1.1E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 PRINTS PR00046 Major sigma-70 factor signature 471 486 1.1E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 Pfam PF04545 Sigma-70, region 4 446 499 5.1E-17 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 Pfam PF04539 Sigma-70 region 3 356 432 7.4E-18 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 301 314 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 471 497 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 SUPERFAMILY SSF88659 409 502 2.06E-24 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HL41_04220 01e7c7678603b62b0169cfb606b4d9cb 514 Pfam PF04542 Sigma-70 region 2 277 346 5.2E-20 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HL41_07540 524d077efcdd7161cef314522becaf6b 149 SUPERFAMILY SSF54637 9 136 1.46E-24 T 14-10-2018 IPR029069 HotDog domain superfamily HL41_07540 524d077efcdd7161cef314522becaf6b 149 Gene3D G3DSA:3.10.129.10 4 145 3.2E-42 T 14-10-2018 HL41_07540 524d077efcdd7161cef314522becaf6b 149 Pfam PF03061 Thioesterase superfamily 53 123 1.0E-9 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 HL41_07540 524d077efcdd7161cef314522becaf6b 149 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 23 135 4.5E-21 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 HL41_09095 422b7b565ce5dbbdf47ff9d0147216b5 256 SUPERFAMILY SSF52540 1 230 1.07E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_09095 422b7b565ce5dbbdf47ff9d0147216b5 256 SMART SM00382 28 217 1.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_09095 422b7b565ce5dbbdf47ff9d0147216b5 256 Gene3D G3DSA:3.40.50.300 1 252 7.6E-65 T 14-10-2018 HL41_09095 422b7b565ce5dbbdf47ff9d0147216b5 256 Pfam PF00005 ABC transporter 19 168 3.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_03375 d74dd6da6f1d609144735a9193455daa 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 14-10-2018 IPR020845 AMP-binding, conserved site HL41_03375 d74dd6da6f1d609144735a9193455daa 538 Gene3D G3DSA:3.30.300.310 431 533 2.9E-32 T 14-10-2018 HL41_03375 d74dd6da6f1d609144735a9193455daa 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 522 7.3E-26 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HL41_03375 d74dd6da6f1d609144735a9193455daa 538 Gene3D G3DSA:3.40.50.12780 1 428 5.9E-121 T 14-10-2018 HL41_03375 d74dd6da6f1d609144735a9193455daa 538 SUPERFAMILY SSF56801 20 532 1.44E-142 T 14-10-2018 HL41_03375 d74dd6da6f1d609144735a9193455daa 538 Pfam PF00501 AMP-binding enzyme 33 435 8.5E-76 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 SUPERFAMILY SSF158472 250 299 3.4E-6 T 14-10-2018 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 SMART SM00304 248 302 2.1E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 SUPERFAMILY SSF47384 427 497 4.71E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 SUPERFAMILY SSF55785 297 411 9.9E-9 T 14-10-2018 IPR035965 PAS domain superfamily HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 SMART SM00388 434 500 2.8E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 Pfam PF08448 PAS fold 315 420 4.1E-8 T 14-10-2018 IPR013656 PAS fold-4 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 SMART SM00387 542 651 5.5E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 Pfam PF00672 HAMP domain 252 297 1.0E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 Gene3D G3DSA:1.10.287.130 430 498 1.3E-20 T 14-10-2018 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 Gene3D G3DSA:3.30.450.20 307 429 8.1E-13 T 14-10-2018 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 543 650 5.5E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 Gene3D G3DSA:3.30.565.10 502 652 1.7E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 Gene3D G3DSA:1.20.1480.50 217 306 1.4E-6 T 14-10-2018 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 595 2.7E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 599 609 2.7E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 648 2.7E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 612 630 2.7E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 Pfam PF11845 Protein of unknown function (DUF3365) 26 212 2.6E-38 T 14-10-2018 IPR021796 Protein of unknown function DUF3365 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 Pfam PF00512 His Kinase A (phospho-acceptor) domain 436 497 5.0E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_02065 ad7eb34e2eb536c06861d5606cc1b19e 657 SUPERFAMILY SSF55874 491 649 4.32E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_00535 2d54b5a2efb2671c8619f2444dbee61c 139 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 7 139 1.3E-48 T 14-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 HL41_00535 2d54b5a2efb2671c8619f2444dbee61c 139 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 86 137 3.2E-11 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HL41_00535 2d54b5a2efb2671c8619f2444dbee61c 139 Pfam PF00460 Flagella basal body rod protein 9 34 7.5E-6 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HL41_06485 cd67843f71db72b6a32064278db77215 346 Pfam PF02272 DHHA1 domain 213 306 5.0E-6 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HL41_06485 cd67843f71db72b6a32064278db77215 346 Gene3D G3DSA:3.90.1640.10 32 205 1.1E-25 T 14-10-2018 HL41_06485 cd67843f71db72b6a32064278db77215 346 Pfam PF01368 DHH family 33 170 3.4E-9 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HL41_06485 cd67843f71db72b6a32064278db77215 346 SUPERFAMILY SSF64182 37 309 7.59E-44 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SUPERFAMILY SSF47781 421 600 3.71E-62 T 14-10-2018 IPR010994 RuvA domain 2-like HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SUPERFAMILY SSF52113 611 685 1.25E-20 T 14-10-2018 IPR036420 BRCT domain superfamily HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Gene3D G3DSA:3.30.470.90 82 335 3.1E-102 T 14-10-2018 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Hamap MF_01588 DNA ligase [ligA]. 13 684 53.017 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Gene3D G3DSA:1.10.287.610 12 81 1.5E-32 T 14-10-2018 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SUPERFAMILY SSF50249 335 417 3.6E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 611 684 1.1E-16 T 14-10-2018 IPR001357 BRCT domain HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 348 363 - T 14-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Gene3D G3DSA:2.20.70.80 408 445 5.6E-11 T 14-10-2018 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 PIRSF PIRSF001604 6 688 5.2E-269 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SMART SM00292 610 687 1.8E-16 T 14-10-2018 IPR001357 BRCT domain HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Gene3D G3DSA:3.40.50.10190 607 688 9.6E-28 T 14-10-2018 IPR036420 BRCT domain superfamily HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 22 680 1.9E-271 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Pfam PF12826 Helix-hairpin-helix motif 526 589 6.6E-27 T 14-10-2018 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Gene3D G3DSA:1.10.150.20 452 519 1.0E-23 T 14-10-2018 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 15 334 3.1E-133 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Pfam PF14520 Helix-hairpin-helix domain 462 518 5.7E-7 T 14-10-2018 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 128 157 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 338 415 1.2E-34 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SMART SM00532 14 464 1.5E-274 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Gene3D G3DSA:1.10.150.20 520 602 5.2E-31 T 14-10-2018 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 424 450 3.5E-9 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SMART SM00278 528 547 340.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SMART SM00278 560 579 0.56 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SMART SM00278 462 481 16.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SMART SM00278 496 515 39.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 Gene3D G3DSA:2.40.50.140 336 406 5.0E-33 T 14-10-2018 HL41_03685 13b1586d297ec42cb445ec4bf97ccbfc 688 SUPERFAMILY SSF56091 13 332 6.08E-122 T 14-10-2018 HL41_06980 064ce6103c4515f3552a9612f98abfea 339 Pfam PF05954 Phage late control gene D protein (GPD) 99 318 2.9E-11 T 14-10-2018 HL41_06980 064ce6103c4515f3552a9612f98abfea 339 SUPERFAMILY SSF69279 44 182 1.7E-14 T 14-10-2018 HL41_01220 4a927449edee0638ac627101b6f595af 335 SUPERFAMILY SSF52402 15 190 4.67E-28 T 14-10-2018 HL41_01220 4a927449edee0638ac627101b6f595af 335 PIRSF PIRSF000089 11 335 5.2E-83 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 HL41_01220 4a927449edee0638ac627101b6f595af 335 Pfam PF01012 Electron transfer flavoprotein domain 23 176 3.5E-23 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HL41_01220 4a927449edee0638ac627101b6f595af 335 Gene3D G3DSA:3.40.50.1220 208 335 3.9E-49 T 14-10-2018 HL41_01220 4a927449edee0638ac627101b6f595af 335 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 214 296 1.9E-33 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 HL41_01220 4a927449edee0638ac627101b6f595af 335 Gene3D G3DSA:3.40.50.620 2 200 2.9E-36 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_01220 4a927449edee0638ac627101b6f595af 335 SMART SM00893 15 200 3.8E-9 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HL41_01220 4a927449edee0638ac627101b6f595af 335 SUPERFAMILY SSF52467 214 333 3.82E-41 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 361 391 - T 14-10-2018 IPR030390 RNA methyltransferase TrmA, active site HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 252 430 4.3E-16 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 Gene3D G3DSA:3.40.50.150 75 423 3.0E-64 T 14-10-2018 HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 412 422 - T 14-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 Gene3D G3DSA:3.40.1350.30 123 262 3.0E-64 T 14-10-2018 HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 14 422 9.4E-72 T 14-10-2018 HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 SUPERFAMILY SSF53335 62 429 4.22E-56 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 Pfam PF01938 TRAM domain 4 54 4.2E-9 T 14-10-2018 IPR002792 TRAM domain HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 SUPERFAMILY SSF50249 3 61 2.0E-11 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_00100 ad46410d244f67c052f81be5b8d8b165 431 Gene3D G3DSA:2.40.50.140 1 74 1.3E-22 T 14-10-2018 HL41_04595 854c6339bb433f871370053eb1b85e11 94 Pfam PF02325 YGGT family 15 83 7.7E-24 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 HL41_05460 2f9d3240b709905273f3340438a314f9 694 SUPERFAMILY SSF52540 10 283 5.81E-109 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05460 2f9d3240b709905273f3340438a314f9 694 Gene3D G3DSA:2.40.30.10 295 406 1.7E-42 T 14-10-2018 HL41_05460 2f9d3240b709905273f3340438a314f9 694 Pfam PF00679 Elongation factor G C-terminus 600 686 1.3E-31 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like HL41_05460 2f9d3240b709905273f3340438a314f9 694 Gene3D G3DSA:3.30.70.870 407 481 1.3E-31 T 14-10-2018 HL41_05460 2f9d3240b709905273f3340438a314f9 694 Pfam PF00009 Elongation factor Tu GTP binding domain 11 283 6.8E-69 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 Pfam PF03764 Elongation factor G, domain IV 480 598 8.2E-47 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 SUPERFAMILY SSF54980 600 691 6.83E-31 T 14-10-2018 IPR035647 EF-G domain III/V-like HL41_05460 2f9d3240b709905273f3340438a314f9 694 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site HL41_05460 2f9d3240b709905273f3340438a314f9 694 SUPERFAMILY SSF54980 404 480 1.04E-24 T 14-10-2018 IPR035647 EF-G domain III/V-like HL41_05460 2f9d3240b709905273f3340438a314f9 694 Gene3D G3DSA:3.40.50.300 7 294 4.9E-116 T 14-10-2018 HL41_05460 2f9d3240b709905273f3340438a314f9 694 SMART SM00838 600 687 1.0E-55 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like HL41_05460 2f9d3240b709905273f3340438a314f9 694 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.1E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 PRINTS PR00315 GTP-binding elongation factor signature 60 68 1.1E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.1E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.1E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 PRINTS PR00315 GTP-binding elongation factor signature 132 141 1.1E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 SMART SM00889 481 598 3.2E-71 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 TIGRFAM TIGR00484 EF-G: translation elongation factor G 9 692 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HL41_05460 2f9d3240b709905273f3340438a314f9 694 SUPERFAMILY SSF50447 249 401 4.8E-35 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_05460 2f9d3240b709905273f3340438a314f9 694 Gene3D G3DSA:3.30.70.240 604 674 1.4E-93 T 14-10-2018 HL41_05460 2f9d3240b709905273f3340438a314f9 694 Gene3D G3DSA:3.30.230.10 485 687 1.4E-93 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_05460 2f9d3240b709905273f3340438a314f9 694 Pfam PF14492 Elongation Factor G, domain II 405 478 9.3E-33 T 14-10-2018 HL41_05460 2f9d3240b709905273f3340438a314f9 694 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 182 3.4E-29 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 SUPERFAMILY SSF54211 483 599 3.79E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_05460 2f9d3240b709905273f3340438a314f9 694 Pfam PF03144 Elongation factor Tu domain 2 325 392 3.0E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HL41_05460 2f9d3240b709905273f3340438a314f9 694 Hamap MF_00054_B Elongation factor G [fusA]. 8 691 111.691 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HL41_01110 5a56b8100083d4573913d15ee8cef003 235 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 10 230 29.676 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 HL41_01110 5a56b8100083d4573913d15ee8cef003 235 Pfam PF01168 Alanine racemase, N-terminal domain 45 231 5.4E-17 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HL41_01110 5a56b8100083d4573913d15ee8cef003 235 Gene3D G3DSA:3.20.20.10 1 234 7.4E-76 T 14-10-2018 IPR029066 PLP-binding barrel HL41_01110 5a56b8100083d4573913d15ee8cef003 235 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 11 231 1.7E-56 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 HL41_01110 5a56b8100083d4573913d15ee8cef003 235 PIRSF PIRSF004848 1 235 1.4E-72 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 HL41_01110 5a56b8100083d4573913d15ee8cef003 235 SUPERFAMILY SSF51419 8 229 6.54E-70 T 14-10-2018 IPR029066 PLP-binding barrel HL41_08060 e07cfc4039b3c562f08cda220f7645c7 72 PRINTS PR01249 Ribosomal protein L31 signature 2 19 6.3E-20 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_08060 e07cfc4039b3c562f08cda220f7645c7 72 PRINTS PR01249 Ribosomal protein L31 signature 46 64 6.3E-20 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_08060 e07cfc4039b3c562f08cda220f7645c7 72 PRINTS PR01249 Ribosomal protein L31 signature 31 46 6.3E-20 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_08060 e07cfc4039b3c562f08cda220f7645c7 72 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_08060 e07cfc4039b3c562f08cda220f7645c7 72 Gene3D G3DSA:2.30.170.50 1 69 1.9E-30 T 14-10-2018 HL41_08060 e07cfc4039b3c562f08cda220f7645c7 72 SUPERFAMILY SSF143800 1 67 8.24E-26 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08060 e07cfc4039b3c562f08cda220f7645c7 72 Pfam PF01197 Ribosomal protein L31 1 64 9.6E-31 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_08060 e07cfc4039b3c562f08cda220f7645c7 72 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 2.0E-28 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_08060 e07cfc4039b3c562f08cda220f7645c7 72 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 28.262 T 14-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_04035 fd9101b0a389493d3256c6b64cf11b04 288 Pfam PF08668 HDOD domain 20 208 2.4E-63 T 14-10-2018 IPR013976 Metal-dependent hydrolase HDOD HL41_04035 fd9101b0a389493d3256c6b64cf11b04 288 Gene3D G3DSA:1.10.3210.10 2 282 4.3E-80 T 14-10-2018 HL41_04035 fd9101b0a389493d3256c6b64cf11b04 288 SUPERFAMILY SSF109604 12 271 4.52E-70 T 14-10-2018 HL41_04035 fd9101b0a389493d3256c6b64cf11b04 288 TIGRFAM TIGR00277 HDIG: HDIG domain 107 208 1.4E-13 T 14-10-2018 IPR006675 HDIG domain HL41_04035 fd9101b0a389493d3256c6b64cf11b04 288 SMART SM00471 104 240 3.9E-8 T 14-10-2018 IPR003607 HD/PDEase domain HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 SUPERFAMILY SSF55874 577 742 3.8E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 SUPERFAMILY SSF47384 516 585 5.1E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 Gene3D G3DSA:3.30.450.20 381 512 3.8E-23 T 14-10-2018 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 Gene3D G3DSA:1.10.287.130 514 586 1.5E-20 T 14-10-2018 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 SMART SM00091 394 459 2.5E-5 T 14-10-2018 IPR000014 PAS domain HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 SUPERFAMILY SSF55785 384 504 7.33E-16 T 14-10-2018 IPR035965 PAS domain superfamily HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 Pfam PF02743 Cache domain 57 332 3.6E-22 T 14-10-2018 IPR033479 Double Cache domain 1 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 Pfam PF08448 PAS fold 401 507 6.9E-10 T 14-10-2018 IPR013656 PAS fold-4 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 Gene3D G3DSA:3.30.450.20 201 350 3.6E-19 T 14-10-2018 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 390 512 1.0E-14 T 14-10-2018 IPR000014 PAS domain HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 630 741 9.7E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 Pfam PF00512 His Kinase A (phospho-acceptor) domain 521 584 1.3E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 Gene3D G3DSA:3.30.565.10 587 749 1.8E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 684 694 7.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 666 680 7.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 726 739 7.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 697 715 7.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 SMART SM00388 521 587 2.0E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_08235 bbb5b58debdf93ca6c95c918411cf8e6 751 SMART SM00387 629 742 2.3E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_06735 d905291af332b19cec1a1e6d4ec8c649 649 Pfam PF12439 Glycogen debranching enzyme N terminal 13 229 1.1E-43 T 14-10-2018 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal HL41_06735 d905291af332b19cec1a1e6d4ec8c649 649 SUPERFAMILY SSF48208 179 640 7.29E-44 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 HL41_06735 d905291af332b19cec1a1e6d4ec8c649 649 Pfam PF06202 Amylo-alpha-1,6-glucosidase 288 637 1.7E-81 T 14-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 HL41_06735 d905291af332b19cec1a1e6d4ec8c649 649 Gene3D G3DSA:1.50.10.10 476 644 1.6E-13 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 HL41_08335 3d6862133604047f94697948c4719702 339 Gene3D G3DSA:3.40.190.10 103 280 6.4E-116 T 14-10-2018 HL41_08335 3d6862133604047f94697948c4719702 339 Gene3D G3DSA:3.40.190.10 30 324 6.4E-116 T 14-10-2018 HL41_08335 3d6862133604047f94697948c4719702 339 PIRSF PIRSF002756 11 339 6.0E-110 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 HL41_08335 3d6862133604047f94697948c4719702 339 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 29 335 8.8E-112 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 HL41_08335 3d6862133604047f94697948c4719702 339 SUPERFAMILY SSF53850 28 338 7.04E-96 T 14-10-2018 HL41_08335 3d6862133604047f94697948c4719702 339 Pfam PF12849 PBP superfamily domain 22 306 1.8E-61 T 14-10-2018 IPR024370 PBP domain HL41_04120 d70c57a42cd6b6669177f505bafe0522 548 PIRSF PIRSF002741 1 542 6.6E-154 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HL41_04120 d70c57a42cd6b6669177f505bafe0522 548 Gene3D G3DSA:3.90.76.10 74 191 9.9E-158 T 14-10-2018 HL41_04120 d70c57a42cd6b6669177f505bafe0522 548 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 91 113 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site HL41_04120 d70c57a42cd6b6669177f505bafe0522 548 Gene3D G3DSA:3.10.105.10 287 508 9.9E-158 T 14-10-2018 HL41_04120 d70c57a42cd6b6669177f505bafe0522 548 SUPERFAMILY SSF53850 41 538 7.24E-142 T 14-10-2018 HL41_04120 d70c57a42cd6b6669177f505bafe0522 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 446 1.1E-96 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain HL41_04120 d70c57a42cd6b6669177f505bafe0522 548 Gene3D G3DSA:3.40.190.10 56 522 9.9E-158 T 14-10-2018 HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 670 887 2.3E-54 T 14-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 Gene3D G3DSA:3.30.420.40 5 260 5.4E-82 T 14-10-2018 HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 Gene3D G3DSA:3.30.420.40 325 576 6.6E-93 T 14-10-2018 HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 Gene3D G3DSA:3.30.420.40 97 246 5.4E-82 T 14-10-2018 HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 SUPERFAMILY SSF53067 324 576 3.77E-41 T 14-10-2018 HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 SUPERFAMILY SSF53067 4 260 9.48E-42 T 14-10-2018 HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 261 1.4E-34 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 325 576 2.2E-41 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 5 259 1.6E-47 T 14-10-2018 IPR008275 CoA enzyme activase HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 325 575 2.5E-54 T 14-10-2018 IPR008275 CoA enzyme activase HL41_00095 309f6b5e8399d2a6ea0c0a212195788a 1399 Gene3D G3DSA:3.30.420.40 419 559 6.6E-93 T 14-10-2018 HL41_07845 13645f7e9be857dba5b3f4f69dcb334f 144 Gene3D G3DSA:3.30.1490.190 87 144 3.6E-14 T 14-10-2018 HL41_07845 13645f7e9be857dba5b3f4f69dcb334f 144 Pfam PF01475 Ferric uptake regulator family 15 133 1.1E-26 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HL41_07845 13645f7e9be857dba5b3f4f69dcb334f 144 SUPERFAMILY SSF46785 7 138 4.29E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_07845 13645f7e9be857dba5b3f4f69dcb334f 144 Gene3D G3DSA:1.10.10.10 3 86 2.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_03680 9727a25b8e1b92a9939611ff556510db 123 Gene3D G3DSA:3.30.1130.10 9 123 4.4E-42 T 14-10-2018 HL41_03680 9727a25b8e1b92a9939611ff556510db 123 PIRSF PIRSF027377 1 123 1.1E-52 T 14-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 HL41_03680 9727a25b8e1b92a9939611ff556510db 123 SUPERFAMILY SSF55620 5 116 3.78E-31 T 14-10-2018 HL41_03680 9727a25b8e1b92a9939611ff556510db 123 Pfam PF14489 QueF-like protein 47 122 8.8E-30 T 14-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 HL41_03680 9727a25b8e1b92a9939611ff556510db 123 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 123 47.192 T 14-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 HL41_03680 9727a25b8e1b92a9939611ff556510db 123 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 14 122 1.1E-47 T 14-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 HL41_02250 c43c1a4d6afce6ff08404cca9ba34ea4 160 Gene3D G3DSA:2.40.10.330 72 123 3.9E-33 T 14-10-2018 HL41_02250 c43c1a4d6afce6ff08404cca9ba34ea4 160 Gene3D G3DSA:3.10.50.40 4 152 3.9E-33 T 14-10-2018 HL41_02250 c43c1a4d6afce6ff08404cca9ba34ea4 160 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 9 78 4.9E-6 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain HL41_02250 c43c1a4d6afce6ff08404cca9ba34ea4 160 SUPERFAMILY SSF54534 5 142 2.95E-18 T 14-10-2018 HL41_06530 0ed4fd8f5cab9276e9cd0507513540bd 566 SMART SM00382 286 473 7.1E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_06530 0ed4fd8f5cab9276e9cd0507513540bd 566 SMART SM00382 34 219 2.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_06530 0ed4fd8f5cab9276e9cd0507513540bd 566 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_06530 0ed4fd8f5cab9276e9cd0507513540bd 566 SUPERFAMILY SSF52540 258 476 5.33E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_06530 0ed4fd8f5cab9276e9cd0507513540bd 566 SUPERFAMILY SSF52540 8 230 5.44E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_06530 0ed4fd8f5cab9276e9cd0507513540bd 566 Gene3D G3DSA:3.40.50.300 3 243 1.1E-62 T 14-10-2018 HL41_06530 0ed4fd8f5cab9276e9cd0507513540bd 566 Gene3D G3DSA:3.40.50.300 253 489 2.8E-63 T 14-10-2018 HL41_06530 0ed4fd8f5cab9276e9cd0507513540bd 566 Pfam PF00005 ABC transporter 25 170 4.9E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_06530 0ed4fd8f5cab9276e9cd0507513540bd 566 Pfam PF00005 ABC transporter 278 417 4.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_04685 5100a20c592d3a6600d14f31204b4905 431 Gene3D G3DSA:3.30.565.10 274 428 5.6E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_04685 5100a20c592d3a6600d14f31204b4905 431 SMART SM00388 215 280 2.4E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_04685 5100a20c592d3a6600d14f31204b4905 431 SUPERFAMILY SSF55874 278 428 8.91E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_04685 5100a20c592d3a6600d14f31204b4905 431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 320 427 2.9E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_04685 5100a20c592d3a6600d14f31204b4905 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 427 8.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_04685 5100a20c592d3a6600d14f31204b4905 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 389 8.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_04685 5100a20c592d3a6600d14f31204b4905 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 408 8.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_04685 5100a20c592d3a6600d14f31204b4905 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 375 8.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_04685 5100a20c592d3a6600d14f31204b4905 431 Gene3D G3DSA:1.10.287.130 200 273 1.1E-12 T 14-10-2018 HL41_04685 5100a20c592d3a6600d14f31204b4905 431 SMART SM00387 320 430 1.3E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_04685 5100a20c592d3a6600d14f31204b4905 431 Pfam PF00512 His Kinase A (phospho-acceptor) domain 217 272 3.6E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_04685 5100a20c592d3a6600d14f31204b4905 431 SUPERFAMILY SSF47384 211 274 1.79E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HL41_02675 bd65213d75cee20549afa2b4cbe93b65 236 Gene3D G3DSA:3.30.230.70 14 235 1.1E-55 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HL41_02675 bd65213d75cee20549afa2b4cbe93b65 236 Pfam PF01138 3' exoribonuclease family, domain 1 10 138 2.3E-21 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HL41_02675 bd65213d75cee20549afa2b4cbe93b65 236 Hamap MF_00564 Ribonuclease PH [rph]. 11 235 39.454 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 HL41_02675 bd65213d75cee20549afa2b4cbe93b65 236 SUPERFAMILY SSF54211 1 179 5.57E-42 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_02675 bd65213d75cee20549afa2b4cbe93b65 236 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 234 2.0E-96 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 HL41_02675 bd65213d75cee20549afa2b4cbe93b65 236 Pfam PF03725 3' exoribonuclease family, domain 2 158 221 1.3E-10 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HL41_02675 bd65213d75cee20549afa2b4cbe93b65 236 SUPERFAMILY SSF55666 150 234 5.76E-21 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HL41_02675 bd65213d75cee20549afa2b4cbe93b65 236 ProSitePatterns PS01277 Ribonuclease PH signature. 114 126 - T 14-10-2018 IPR018336 Ribonuclease PH, conserved site HL41_07995 b39d2bf6359a6810d0d66c690610e49e 141 SMART SM00226 1 137 3.5E-56 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I HL41_07995 b39d2bf6359a6810d0d66c690610e49e 141 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 134 4.2E-29 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I HL41_07995 b39d2bf6359a6810d0d66c690610e49e 141 SUPERFAMILY SSF52788 1 135 9.81E-41 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily HL41_07995 b39d2bf6359a6810d0d66c690610e49e 141 Gene3D G3DSA:3.40.50.2300 1 137 1.2E-47 T 14-10-2018 HL41_01385 13459c95b88db2edcaa7cb6c184f7933 307 Pfam PF16199 Radical_SAM C-terminal domain 211 291 8.9E-22 T 14-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 HL41_01385 13459c95b88db2edcaa7cb6c184f7933 307 SMART SM00729 23 250 2.3E-44 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_01385 13459c95b88db2edcaa7cb6c184f7933 307 Gene3D G3DSA:3.80.30.20 71 301 1.8E-18 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HL41_01385 13459c95b88db2edcaa7cb6c184f7933 307 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 6 306 2.4E-106 T 14-10-2018 IPR005911 Protein YhcC-like GO:0051536 HL41_01385 13459c95b88db2edcaa7cb6c184f7933 307 Pfam PF04055 Radical SAM superfamily 43 204 1.1E-20 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_01385 13459c95b88db2edcaa7cb6c184f7933 307 SUPERFAMILY SSF102114 10 272 5.1E-50 T 14-10-2018 HL41_04500 9c604ae9327cebd90b52addcd1fc2255 277 Gene3D G3DSA:3.40.50.300 1 228 9.9E-71 T 14-10-2018 HL41_04500 9c604ae9327cebd90b52addcd1fc2255 277 SMART SM00382 26 206 2.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_04500 9c604ae9327cebd90b52addcd1fc2255 277 Pfam PF00005 ABC transporter 18 158 1.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_04500 9c604ae9327cebd90b52addcd1fc2255 277 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_04500 9c604ae9327cebd90b52addcd1fc2255 277 SUPERFAMILY SSF52540 2 225 6.16E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08625 5694c859500b5377f7f227bb7fa8a8a5 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 107 118 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08625 5694c859500b5377f7f227bb7fa8a8a5 442 Pfam PF13183 4Fe-4S dicluster domain 47 121 5.9E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_08625 5694c859500b5377f7f227bb7fa8a8a5 442 SUPERFAMILY SSF46548 37 134 1.31E-13 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_08625 5694c859500b5377f7f227bb7fa8a8a5 442 Gene3D G3DSA:1.10.1060.10 16 137 3.4E-8 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_08625 5694c859500b5377f7f227bb7fa8a8a5 442 Pfam PF02754 Cysteine-rich domain 322 408 2.1E-10 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_05780 5ab2872b49e8138f5009da2dc846da81 158 SUPERFAMILY SSF52821 44 148 5.76E-20 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily HL41_05780 5ab2872b49e8138f5009da2dc846da81 158 Pfam PF00581 Rhodanese-like domain 55 146 1.6E-8 T 14-10-2018 IPR001763 Rhodanese-like domain HL41_05780 5ab2872b49e8138f5009da2dc846da81 158 SMART SM00450 53 151 2.8E-11 T 14-10-2018 IPR001763 Rhodanese-like domain HL41_05780 5ab2872b49e8138f5009da2dc846da81 158 Gene3D G3DSA:3.40.250.10 50 153 1.2E-19 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily HL41_07770 26f1d2867453963f912cf40bad969f6c 1101 Pfam PF00176 SNF2 family N-terminal domain 119 358 2.1E-16 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 HL41_07770 26f1d2867453963f912cf40bad969f6c 1101 Gene3D G3DSA:3.40.50.300 393 608 5.2E-46 T 14-10-2018 HL41_07770 26f1d2867453963f912cf40bad969f6c 1101 Pfam PF13020 Domain of unknown function (DUF3883) 983 1069 2.5E-20 T 14-10-2018 IPR024975 Domain of unknown function DUF3883 HL41_07770 26f1d2867453963f912cf40bad969f6c 1101 SUPERFAMILY SSF52540 214 616 9.61E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07770 26f1d2867453963f912cf40bad969f6c 1101 SUPERFAMILY SSF52540 81 282 6.29E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07770 26f1d2867453963f912cf40bad969f6c 1101 SMART SM00487 94 296 2.7E-18 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HL41_07770 26f1d2867453963f912cf40bad969f6c 1101 Gene3D G3DSA:3.40.50.10810 94 388 1.9E-59 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily HL41_07770 26f1d2867453963f912cf40bad969f6c 1101 SMART SM00490 498 578 2.0E-26 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_07770 26f1d2867453963f912cf40bad969f6c 1101 Pfam PF00271 Helicase conserved C-terminal domain 478 578 1.7E-23 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 Gene3D G3DSA:3.30.160.40 215 300 2.7E-24 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 207 5.4E-76 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 Gene3D G3DSA:3.40.190.10 3 203 1.5E-78 T 14-10-2018 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 Gene3D G3DSA:3.40.190.10 100 196 1.5E-78 T 14-10-2018 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 291 37.294 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 289 2.8E-107 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 PIRSF PIRSF001438 1 304 2.1E-113 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 220 289 6.2E-19 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 PRINTS PR00151 Porphobilinogen deaminase signature 42 62 1.2E-46 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 PRINTS PR00151 Porphobilinogen deaminase signature 119 136 1.2E-46 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 PRINTS PR00151 Porphobilinogen deaminase signature 224 241 1.2E-46 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 PRINTS PR00151 Porphobilinogen deaminase signature 138 155 1.2E-46 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 PRINTS PR00151 Porphobilinogen deaminase signature 73 92 1.2E-46 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 225 241 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 SUPERFAMILY SSF54782 214 302 4.84E-25 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03645 1f8e78513a831015b9201655c9c6aa7b 304 SUPERFAMILY SSF53850 2 213 9.88E-76 T 14-10-2018 HL41_08680 0eda247ffc743b2a4201daa12e7aa111 160 Gene3D G3DSA:3.30.460.80 1 128 1.2E-41 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08680 0eda247ffc743b2a4201daa12e7aa111 160 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 109 130 - T 14-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08680 0eda247ffc743b2a4201daa12e7aa111 160 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 81 144 6.0E-14 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08680 0eda247ffc743b2a4201daa12e7aa111 160 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 31 148 4.5E-44 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08680 0eda247ffc743b2a4201daa12e7aa111 160 SUPERFAMILY SSF143243 4 149 4.97E-51 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08680 0eda247ffc743b2a4201daa12e7aa111 160 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 1 158 28.64 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08680 0eda247ffc743b2a4201daa12e7aa111 160 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 29 149 7.7E-44 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08170 353f7ed8e4f720aa583f39944d366755 270 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 266 8.1E-93 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_08170 353f7ed8e4f720aa583f39944d366755 270 PIRSF PIRSF000161 1 269 1.9E-84 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_08170 353f7ed8e4f720aa583f39944d366755 270 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 3 266 33.969 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_08170 353f7ed8e4f720aa583f39944d366755 270 Gene3D G3DSA:3.40.50.720 6 265 1.2E-99 T 14-10-2018 HL41_08170 353f7ed8e4f720aa583f39944d366755 270 SUPERFAMILY SSF51735 3 268 1.89E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_08170 353f7ed8e4f720aa583f39944d366755 270 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 152 169 - T 14-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_08170 353f7ed8e4f720aa583f39944d366755 270 SUPERFAMILY SSF55347 129 237 8.07E-35 T 14-10-2018 HL41_08170 353f7ed8e4f720aa583f39944d366755 270 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 127 2.6E-35 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_08170 353f7ed8e4f720aa583f39944d366755 270 Gene3D G3DSA:3.30.360.10 129 235 1.2E-99 T 14-10-2018 HL41_08170 353f7ed8e4f720aa583f39944d366755 270 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 130 265 4.5E-46 T 14-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_06430 06cc4bc9d06d475fab4cbddb52b28770 293 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 290 1.5E-129 T 14-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 HL41_06430 06cc4bc9d06d475fab4cbddb52b28770 293 Pfam PF00483 Nucleotidyl transferase 2 242 6.9E-64 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HL41_06430 06cc4bc9d06d475fab4cbddb52b28770 293 Gene3D G3DSA:3.90.550.10 1 293 2.2E-81 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_06430 06cc4bc9d06d475fab4cbddb52b28770 293 SUPERFAMILY SSF53448 1 290 2.71E-82 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_08855 41401b6d932f963d0a46f7b21c4ef245 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08855 41401b6d932f963d0a46f7b21c4ef245 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.2E-24 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08855 41401b6d932f963d0a46f7b21c4ef245 148 SUPERFAMILY SSF55658 1 54 9.77E-19 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal HL41_08855 41401b6d932f963d0a46f7b21c4ef245 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 66 145 2.8E-23 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal HL41_08855 41401b6d932f963d0a46f7b21c4ef245 148 Gene3D G3DSA:3.40.5.10 1 50 3.9E-25 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08855 41401b6d932f963d0a46f7b21c4ef245 148 Gene3D G3DSA:3.10.430.100 60 148 4.4E-25 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily HL41_08855 41401b6d932f963d0a46f7b21c4ef245 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 24.557 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_08855 41401b6d932f963d0a46f7b21c4ef245 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 7.1E-41 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_08855 41401b6d932f963d0a46f7b21c4ef245 148 SUPERFAMILY SSF55653 57 147 1.7E-22 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily HL41_03205 15d94ecf62292bc9920e0b5a416eb69b 401 Pfam PF02687 FtsX-like permease family 306 394 8.9E-15 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HL41_03205 15d94ecf62292bc9920e0b5a416eb69b 401 Pfam PF12704 MacB-like periplasmic core domain 19 239 4.8E-27 T 14-10-2018 IPR025857 MacB-like periplasmic core domain HL41_05190 886469e166cf20f3bbeb0b3567d97680 184 SUPERFAMILY SSF109604 22 176 2.28E-14 T 14-10-2018 HL41_05190 886469e166cf20f3bbeb0b3567d97680 184 Gene3D G3DSA:1.10.3210.10 14 182 1.0E-11 T 14-10-2018 HL41_05190 886469e166cf20f3bbeb0b3567d97680 184 Pfam PF01966 HD domain 22 138 2.8E-11 T 14-10-2018 IPR006674 HD domain HL41_05190 886469e166cf20f3bbeb0b3567d97680 184 TIGRFAM TIGR00277 HDIG: HDIG domain 21 90 9.2E-9 T 14-10-2018 IPR006675 HDIG domain HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 175 17.661 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 PRINTS PR00338 Transcription termination factor NUSG signature 151 167 1.3E-13 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 PRINTS PR00338 Transcription termination factor NUSG signature 133 148 1.3E-13 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 SUPERFAMILY SSF82679 5 107 6.15E-13 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 Pfam PF00467 KOW motif 125 156 1.1E-7 T 14-10-2018 IPR005824 KOW HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 Pfam PF02357 Transcription termination factor nusG 3 105 4.3E-7 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 ProSitePatterns PS01014 Transcription termination factor nusG signature. 158 167 - T 14-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 SMART SM00739 121 148 1.2E-5 T 14-10-2018 IPR005824 KOW HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 175 2.3E-41 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 Gene3D G3DSA:3.30.70.940 1 116 2.2E-15 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 SUPERFAMILY SSF50104 120 175 3.57E-18 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily HL41_08975 8ad503fc0afde35b9875ed540c2d8317 175 Gene3D G3DSA:2.30.30.30 117 175 3.2E-26 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 HL41_09200 abec16c117697359386a92aba29f66b1 180 Pfam PF13183 4Fe-4S dicluster domain 31 94 2.3E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_09200 abec16c117697359386a92aba29f66b1 180 Gene3D G3DSA:1.10.1060.10 3 111 2.3E-11 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_09200 abec16c117697359386a92aba29f66b1 180 SUPERFAMILY SSF46548 14 109 1.74E-18 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_09200 abec16c117697359386a92aba29f66b1 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 35 46 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_09200 abec16c117697359386a92aba29f66b1 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_09235 abec16c117697359386a92aba29f66b1 180 Pfam PF13183 4Fe-4S dicluster domain 31 94 2.3E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_09235 abec16c117697359386a92aba29f66b1 180 Gene3D G3DSA:1.10.1060.10 3 111 2.3E-11 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_09235 abec16c117697359386a92aba29f66b1 180 SUPERFAMILY SSF46548 14 109 1.74E-18 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_09235 abec16c117697359386a92aba29f66b1 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 35 46 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_09235 abec16c117697359386a92aba29f66b1 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_00015 1e5a3e3c9286a15f232d977dbffff3e0 300 Gene3D G3DSA:3.40.50.11800 2 131 1.5E-5 T 14-10-2018 HL41_00015 1e5a3e3c9286a15f232d977dbffff3e0 300 Pfam PF02754 Cysteine-rich domain 4 87 3.5E-10 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_00015 1e5a3e3c9286a15f232d977dbffff3e0 300 Pfam PF02754 Cysteine-rich domain 152 243 6.1E-10 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_09230 1e5a3e3c9286a15f232d977dbffff3e0 300 Gene3D G3DSA:3.40.50.11800 2 131 1.5E-5 T 14-10-2018 HL41_09230 1e5a3e3c9286a15f232d977dbffff3e0 300 Pfam PF02754 Cysteine-rich domain 4 87 3.5E-10 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_09230 1e5a3e3c9286a15f232d977dbffff3e0 300 Pfam PF02754 Cysteine-rich domain 152 243 6.1E-10 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_09205 1e5a3e3c9286a15f232d977dbffff3e0 300 Gene3D G3DSA:3.40.50.11800 2 131 1.5E-5 T 14-10-2018 HL41_09205 1e5a3e3c9286a15f232d977dbffff3e0 300 Pfam PF02754 Cysteine-rich domain 4 87 3.5E-10 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_09205 1e5a3e3c9286a15f232d977dbffff3e0 300 Pfam PF02754 Cysteine-rich domain 152 243 6.1E-10 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_03540 04f9440a015749c11bf3fd5282449b0b 110 SUPERFAMILY SSF54913 3 106 1.48E-32 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta HL41_03540 04f9440a015749c11bf3fd5282449b0b 110 Pfam PF03091 CutA1 divalent ion tolerance protein 8 104 6.7E-32 T 14-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 HL41_03540 04f9440a015749c11bf3fd5282449b0b 110 Gene3D G3DSA:3.30.70.120 1 107 1.6E-37 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HL41_02165 36f2308d03a9fc31ae638b4119b3503b 382 PIRSF PIRSF004810 1 382 1.3E-94 T 14-10-2018 IPR014047 Chromate transporter, long chain HL41_02165 36f2308d03a9fc31ae638b4119b3503b 382 TIGRFAM TIGR00937 2A51: chromate efflux transporter 15 376 1.7E-93 T 14-10-2018 IPR014047 Chromate transporter, long chain HL41_02165 36f2308d03a9fc31ae638b4119b3503b 382 Pfam PF02417 Chromate transporter 217 376 1.3E-34 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 HL41_02165 36f2308d03a9fc31ae638b4119b3503b 382 Pfam PF02417 Chromate transporter 10 170 9.4E-36 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 HL41_03370 e78687c2e6f5cec70b09c81fb98e5347 140 SUPERFAMILY SSF55021 54 134 2.98E-28 T 14-10-2018 HL41_03370 e78687c2e6f5cec70b09c81fb98e5347 140 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 2.0E-6 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 HL41_03370 e78687c2e6f5cec70b09c81fb98e5347 140 Gene3D G3DSA:3.30.70.1150 52 138 2.4E-34 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal HL41_03370 e78687c2e6f5cec70b09c81fb98e5347 140 Hamap MF_00476 Nickel-responsive regulator [nikR]. 4 134 29.754 T 14-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 HL41_03370 e78687c2e6f5cec70b09c81fb98e5347 140 Pfam PF08753 NikR C terminal nickel binding domain 56 131 4.5E-32 T 14-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal HL41_03370 e78687c2e6f5cec70b09c81fb98e5347 140 Gene3D G3DSA:1.10.1220.10 5 50 6.5E-20 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 HL41_03370 e78687c2e6f5cec70b09c81fb98e5347 140 SUPERFAMILY SSF47598 3 50 4.82E-13 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 SMART SM00268 10 341 0.0072 T 14-10-2018 IPR004000 Actin family HL41_07160 6fc20d99907e6078b4152e2b49327837 343 SUPERFAMILY SSF53067 150 332 1.84E-50 T 14-10-2018 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 301 327 7.0E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 7.0E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 7.0E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 50 68 7.0E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 70 93 7.0E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 Gene3D G3DSA:3.30.420.40 13 328 9.0E-135 T 14-10-2018 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 Pfam PF06723 MreB/Mbl protein 10 337 2.6E-150 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 Gene3D G3DSA:3.90.640.10 187 260 9.0E-135 T 14-10-2018 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 SUPERFAMILY SSF53067 9 149 7.34E-40 T 14-10-2018 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 Gene3D G3DSA:3.30.420.40 155 318 9.0E-135 T 14-10-2018 HL41_07160 6fc20d99907e6078b4152e2b49327837 343 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 337 2.9E-158 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HL41_03595 5955a1bad7b580e4b7e956f1648f0cc5 142 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 3 132 3.7E-43 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 HL41_03595 5955a1bad7b580e4b7e956f1648f0cc5 142 Pfam PF01029 NusB family 5 131 6.7E-37 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HL41_03595 5955a1bad7b580e4b7e956f1648f0cc5 142 Gene3D G3DSA:1.10.940.10 1 142 3.9E-46 T 14-10-2018 IPR035926 NusB-like superfamily HL41_03595 5955a1bad7b580e4b7e956f1648f0cc5 142 SUPERFAMILY SSF48013 3 132 6.67E-41 T 14-10-2018 IPR035926 NusB-like superfamily HL41_03595 5955a1bad7b580e4b7e956f1648f0cc5 142 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 134 22.881 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 Gene3D G3DSA:3.30.230.10 441 645 1.8E-80 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 Gene3D G3DSA:2.40.30.10 266 359 5.1E-18 T 14-10-2018 HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 Pfam PF00679 Elongation factor G C-terminus 558 643 4.7E-24 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 Gene3D G3DSA:3.30.70.240 562 632 1.8E-80 T 14-10-2018 HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 SUPERFAMILY SSF50447 238 355 3.0E-16 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 SUPERFAMILY SSF54211 436 557 1.59E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 Pfam PF03764 Elongation factor G, domain IV 436 556 9.4E-42 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 SMART SM00838 558 645 7.8E-28 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 SUPERFAMILY SSF52540 6 254 9.27E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 SUPERFAMILY SSF54980 558 649 2.93E-23 T 14-10-2018 IPR035647 EF-G domain III/V-like HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 SMART SM00889 437 556 8.4E-61 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 SUPERFAMILY SSF54980 362 439 1.04E-18 T 14-10-2018 IPR035647 EF-G domain III/V-like HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 Gene3D G3DSA:3.30.70.870 362 440 8.0E-23 T 14-10-2018 HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 Pfam PF14492 Elongation Factor G, domain II 361 434 6.1E-24 T 14-10-2018 HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 Pfam PF00009 Elongation factor Tu GTP binding domain 8 254 6.9E-20 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_03735 0ce2b824bfd5f4e852dd41ff8a00f387 659 Gene3D G3DSA:3.40.50.300 6 265 4.3E-44 T 14-10-2018 HL41_01500 b4c7d71347b7e79761a26ec13ae5e5e9 432 Gene3D G3DSA:3.20.20.140 12 251 1.4E-11 T 14-10-2018 HL41_01500 b4c7d71347b7e79761a26ec13ae5e5e9 432 SUPERFAMILY SSF89550 19 260 5.3E-15 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HL41_04475 852da7d7f15741dba57d7cca622352a5 426 Pfam PF05140 ResB-like family 12 269 2.6E-66 T 14-10-2018 IPR007816 ResB-like domain HL41_04475 852da7d7f15741dba57d7cca622352a5 426 Pfam PF05140 ResB-like family 339 414 8.2E-13 T 14-10-2018 IPR007816 ResB-like domain HL41_04150 e2dcf7fb90f593c30b29677b3cc0d7fb 335 Gene3D G3DSA:3.40.50.720 113 257 9.9E-39 T 14-10-2018 HL41_04150 e2dcf7fb90f593c30b29677b3cc0d7fb 335 SUPERFAMILY SSF51735 112 251 1.81E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_04150 e2dcf7fb90f593c30b29677b3cc0d7fb 335 SUPERFAMILY SSF81324 9 134 2.09E-22 T 14-10-2018 HL41_04150 e2dcf7fb90f593c30b29677b3cc0d7fb 335 Pfam PF07885 Ion channel 19 92 2.8E-13 T 14-10-2018 IPR013099 Potassium channel domain HL41_04150 e2dcf7fb90f593c30b29677b3cc0d7fb 335 SUPERFAMILY SSF116726 238 330 1.31E-18 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HL41_04150 e2dcf7fb90f593c30b29677b3cc0d7fb 335 Pfam PF02254 TrkA-N domain 116 227 1.0E-31 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HL41_04150 e2dcf7fb90f593c30b29677b3cc0d7fb 335 Pfam PF02080 TrkA-C domain 262 332 6.5E-16 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HL41_04150 e2dcf7fb90f593c30b29677b3cc0d7fb 335 Gene3D G3DSA:1.10.287.70 10 100 1.5E-16 T 14-10-2018 HL41_04150 e2dcf7fb90f593c30b29677b3cc0d7fb 335 Gene3D G3DSA:3.30.70.1450 260 334 2.4E-19 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 458 7.6E-156 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 402 8.9E-20 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 Pfam PF01225 Mur ligase family, catalytic domain 13 110 3.3E-27 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 Gene3D G3DSA:3.40.50.720 12 98 8.0E-34 T 14-10-2018 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 Pfam PF08245 Mur ligase middle domain 117 296 5.0E-29 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 11 465 39.42 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 SUPERFAMILY SSF51984 12 98 3.53E-30 T 14-10-2018 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 Gene3D G3DSA:3.40.1190.10 100 313 1.4E-70 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 Gene3D G3DSA:3.90.190.20 314 467 1.5E-51 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 SUPERFAMILY SSF53623 97 314 2.22E-62 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HL41_04790 83c64feffadf08779fc39da7ed6dd402 467 SUPERFAMILY SSF53244 315 461 6.41E-43 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HL41_01845 008384a0df93afaada29f2bce6ef37e0 156 Pfam PF01252 Signal peptidase (SPase) II 10 151 5.2E-30 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HL41_01845 008384a0df93afaada29f2bce6ef37e0 156 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 155 13.759 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HL41_01845 008384a0df93afaada29f2bce6ef37e0 156 TIGRFAM TIGR00077 lspA: signal peptidase II 4 154 1.1E-29 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HL41_01845 008384a0df93afaada29f2bce6ef37e0 156 ProSitePatterns PS00855 Signal peptidases II signature. 100 112 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HL41_01845 008384a0df93afaada29f2bce6ef37e0 156 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 47 55 2.2E-15 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HL41_01845 008384a0df93afaada29f2bce6ef37e0 156 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 97 112 2.2E-15 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HL41_01845 008384a0df93afaada29f2bce6ef37e0 156 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 133 149 2.2E-15 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 HL41_01525 2c6f967d34df3be7f19ab405b20d091d 263 SUPERFAMILY SSF56300 7 250 3.52E-71 T 14-10-2018 HL41_01525 2c6f967d34df3be7f19ab405b20d091d 263 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 7 258 7.4E-87 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like HL41_01525 2c6f967d34df3be7f19ab405b20d091d 263 Gene3D G3DSA:3.60.21.10 4 263 9.7E-104 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like HL41_01525 2c6f967d34df3be7f19ab405b20d091d 263 PIRSF PIRSF004789 6 263 2.1E-96 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like HL41_01525 2c6f967d34df3be7f19ab405b20d091d 263 Pfam PF13277 YmdB-like protein 10 257 3.5E-99 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like HL41_00280 6d731dab7d483b35224afc4fadc8cdd6 281 Pfam PF02811 PHP domain 3 164 2.1E-13 T 14-10-2018 IPR004013 PHP domain GO:0003824 HL41_00280 6d731dab7d483b35224afc4fadc8cdd6 281 Gene3D G3DSA:3.20.20.140 2 247 2.2E-88 T 14-10-2018 HL41_00280 6d731dab7d483b35224afc4fadc8cdd6 281 Gene3D G3DSA:1.10.150.650 96 166 2.2E-88 T 14-10-2018 HL41_00280 6d731dab7d483b35224afc4fadc8cdd6 281 SUPERFAMILY SSF89550 2 254 5.1E-47 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HL41_00280 6d731dab7d483b35224afc4fadc8cdd6 281 SMART SM00481 2 67 1.2E-20 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SUPERFAMILY SSF55781 125 294 8.29E-25 T 14-10-2018 HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SMART SM00086 376 415 120.0 T 14-10-2018 IPR001610 PAC motif HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SMART SM00086 88 128 0.023 T 14-10-2018 IPR001610 PAC motif HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Pfam PF00989 PAS fold 313 412 1.1E-7 T 14-10-2018 IPR013767 PAS fold GO:0006355 HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Pfam PF13185 GAF domain 149 294 1.1E-20 T 14-10-2018 IPR003018 GAF domain GO:0005515 HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SMART SM00091 304 370 0.0011 T 14-10-2018 IPR000014 PAS domain HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SMART SM00091 16 80 0.0022 T 14-10-2018 IPR000014 PAS domain HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Gene3D G3DSA:3.30.70.270 425 596 1.3E-32 T 14-10-2018 HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Gene3D G3DSA:3.30.450.20 26 137 9.0E-13 T 14-10-2018 HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Gene3D G3DSA:3.20.20.450 597 832 3.2E-71 T 14-10-2018 IPR035919 EAL domain superfamily HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SMART SM00267 415 583 3.5E-21 T 14-10-2018 IPR000160 GGDEF domain HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 310 417 6.3E-9 T 14-10-2018 IPR000014 PAS domain HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 133 6.1E-15 T 14-10-2018 IPR000014 PAS domain HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 422 580 4.0E-20 T 14-10-2018 IPR000160 GGDEF domain HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Gene3D G3DSA:3.30.450.20 309 424 9.5E-11 T 14-10-2018 HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SUPERFAMILY SSF55785 313 413 1.55E-11 T 14-10-2018 IPR035965 PAS domain superfamily HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Pfam PF00990 Diguanylate cyclase, GGDEF domain 429 576 6.5E-23 T 14-10-2018 IPR000160 GGDEF domain HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SUPERFAMILY SSF141868 601 830 5.89E-66 T 14-10-2018 IPR035919 EAL domain superfamily HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SMART SM00052 593 827 4.7E-70 T 14-10-2018 IPR001633 EAL domain HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Pfam PF00563 EAL domain 601 822 5.5E-57 T 14-10-2018 IPR001633 EAL domain HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Gene3D G3DSA:3.30.450.40 138 301 2.9E-27 T 14-10-2018 IPR029016 GAF-like domain superfamily HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SUPERFAMILY SSF55785 22 130 1.05E-14 T 14-10-2018 IPR035965 PAS domain superfamily HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 SUPERFAMILY SSF55073 431 583 1.33E-27 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_04515 9d08c620cdc43375309b34c66323f1e9 840 Pfam PF13426 PAS domain 27 126 4.7E-6 T 14-10-2018 IPR000014 PAS domain HL41_00420 10cefc57d24e74cf052387dbfcc67f21 113 Gene3D G3DSA:3.30.428.10 1 113 1.1E-45 T 14-10-2018 IPR036265 HIT-like superfamily HL41_00420 10cefc57d24e74cf052387dbfcc67f21 113 Pfam PF01230 HIT domain 10 107 2.7E-31 T 14-10-2018 IPR001310 Histidine triad (HIT) protein HL41_00420 10cefc57d24e74cf052387dbfcc67f21 113 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 14-10-2018 IPR019808 Histidine triad, conserved site HL41_00420 10cefc57d24e74cf052387dbfcc67f21 113 PRINTS PR00332 Histidine triad family signature 25 43 8.5E-22 T 14-10-2018 IPR001310 Histidine triad (HIT) protein HL41_00420 10cefc57d24e74cf052387dbfcc67f21 113 PRINTS PR00332 Histidine triad family signature 93 103 8.5E-22 T 14-10-2018 IPR001310 Histidine triad (HIT) protein HL41_00420 10cefc57d24e74cf052387dbfcc67f21 113 PRINTS PR00332 Histidine triad family signature 4 20 8.5E-22 T 14-10-2018 IPR001310 Histidine triad (HIT) protein HL41_00420 10cefc57d24e74cf052387dbfcc67f21 113 SUPERFAMILY SSF54197 1 112 6.38E-44 T 14-10-2018 IPR036265 HIT-like superfamily HL41_07785 66a2c17197c1f1ae5b28d796587e79fe 104 Pfam PF01909 Nucleotidyltransferase domain 10 80 2.6E-12 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 HL41_07785 66a2c17197c1f1ae5b28d796587e79fe 104 Gene3D G3DSA:3.30.460.10 1 102 3.3E-19 T 14-10-2018 HL41_07785 66a2c17197c1f1ae5b28d796587e79fe 104 SUPERFAMILY SSF81301 4 98 2.09E-15 T 14-10-2018 HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 227 327 1.1E-19 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 Pfam PF08676 MutL C terminal dimerisation domain 385 516 6.0E-26 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 SUPERFAMILY SSF54211 232 328 8.34E-20 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 SUPERFAMILY SSF118116 382 559 6.54E-35 T 14-10-2018 IPR037198 MutL, C-terminal domain superfamily HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 SMART SM00853 384 518 3.9E-24 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 Gene3D G3DSA:3.30.230.10 219 327 5.1E-21 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 308 4.9E-86 T 14-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 SUPERFAMILY SSF55874 2 210 9.17E-49 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 SMART SM01340 211 328 3.2E-22 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 130 3.2E-14 T 14-10-2018 HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 557 21.795 T 14-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 Gene3D G3DSA:3.30.1370.100 425 515 5.3E-39 T 14-10-2018 HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 14-10-2018 IPR014762 DNA mismatch repair, conserved site HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 Gene3D G3DSA:3.30.565.10 3 202 1.7E-63 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_05175 61498014c4bd5ef9fd5bce8386d430bf 561 Gene3D G3DSA:2.30.42.20 385 559 5.3E-39 T 14-10-2018 HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 186 5.7E-52 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 ProSitePatterns PS00761 Signal peptidases I signature 3. 151 164 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 Pfam PF00717 Peptidase S24-like 34 116 7.8E-18 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 Gene3D G3DSA:2.10.109.10 121 198 8.4E-17 T 14-10-2018 HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 Gene3D G3DSA:2.10.109.10 24 120 5.8E-31 T 14-10-2018 HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 ProSitePatterns PS00760 Signal peptidases I lysine active site. 94 106 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 SUPERFAMILY SSF51306 26 200 4.03E-60 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 146 165 3.5E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 3.5E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HL41_03035 5cba3046b6bcc8df44bcacf6620a2c6a 203 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 92 104 3.5E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 SUPERFAMILY SSF50249 66 127 2.57E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 SMART SM01185 68 122 6.8E-22 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 14-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 Hamap MF_00141 Elongation factor P [efp]. 2 186 46.688 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 PIRSF PIRSF005901 1 187 3.5E-68 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 Pfam PF09285 Elongation factor P, C-terminal 130 185 2.1E-29 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 Gene3D G3DSA:2.40.50.140 65 128 4.6E-23 T 14-10-2018 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 1.2E-20 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 Gene3D G3DSA:2.30.30.30 1 63 9.9E-24 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 SMART SM00841 130 185 1.8E-36 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 61 1.8E-22 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 SUPERFAMILY SSF50104 3 63 2.53E-16 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 1.7E-77 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 Gene3D G3DSA:2.40.50.140 129 186 4.4E-30 T 14-10-2018 HL41_00375 7bdac8780a407f5e9b160cbd37beffd2 187 SUPERFAMILY SSF50249 130 186 2.91E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_01320 94703398982f183e4d7f566a91a17da0 179 SUPERFAMILY SSF46785 85 159 1.09E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_01320 94703398982f183e4d7f566a91a17da0 179 PIRSF PIRSF019345 3 179 8.5E-52 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HL41_01320 94703398982f183e4d7f566a91a17da0 179 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 8 170 3.6E-40 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HL41_01320 94703398982f183e4d7f566a91a17da0 179 Gene3D G3DSA:1.10.10.10 84 179 1.5E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_01320 94703398982f183e4d7f566a91a17da0 179 Gene3D G3DSA:1.10.10.10 4 83 1.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_01320 94703398982f183e4d7f566a91a17da0 179 Pfam PF04079 Segregation and condensation complex subunit ScpB 11 168 1.1E-51 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HL41_01320 94703398982f183e4d7f566a91a17da0 179 SUPERFAMILY SSF46785 8 81 1.33E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_02255 23cd2f820faf97001533875b5dd950b3 316 SUPERFAMILY SSF52540 16 253 1.38E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02255 23cd2f820faf97001533875b5dd950b3 316 SMART SM00382 31 239 2.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_02255 23cd2f820faf97001533875b5dd950b3 316 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 288 1.8E-12 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HL41_02255 23cd2f820faf97001533875b5dd950b3 316 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 313 3.3E-20 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HL41_02255 23cd2f820faf97001533875b5dd950b3 316 Gene3D G3DSA:3.40.50.300 3 316 2.4E-85 T 14-10-2018 HL41_02255 23cd2f820faf97001533875b5dd950b3 316 Pfam PF00005 ABC transporter 23 181 4.3E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_01250 c8109877dc76766344626a2d91bb8222 260 SUPERFAMILY SSF101386 137 236 4.51E-27 T 14-10-2018 HL41_01250 c8109877dc76766344626a2d91bb8222 260 TIGRFAM TIGR00444 mazG: MazG family protein 16 257 1.9E-80 T 14-10-2018 IPR011551 NTP pyrophosphohydrolase MazG HL41_01250 c8109877dc76766344626a2d91bb8222 260 Gene3D G3DSA:1.10.287.1080 6 129 1.3E-38 T 14-10-2018 HL41_01250 c8109877dc76766344626a2d91bb8222 260 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 163 228 1.1E-12 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HL41_01250 c8109877dc76766344626a2d91bb8222 260 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 32 105 7.9E-25 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HL41_01250 c8109877dc76766344626a2d91bb8222 260 SUPERFAMILY SSF101386 9 107 7.12E-23 T 14-10-2018 HL41_01250 c8109877dc76766344626a2d91bb8222 260 Gene3D G3DSA:1.10.287.1080 131 260 3.5E-43 T 14-10-2018 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 SUPERFAMILY SSF56553 54 173 3.4E-38 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 Gene3D G3DSA:1.10.150.20 222 319 1.4E-30 T 14-10-2018 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 SUPERFAMILY SSF47789 246 318 4.05E-25 T 14-10-2018 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 Gene3D G3DSA:2.170.120.12 54 172 1.3E-84 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 4 312 36.31 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 65 158 1.0E-21 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 SMART SM00662 24 229 3.4E-82 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 303 4.4E-25 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 SUPERFAMILY SSF55257 11 227 4.61E-31 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 258 321 8.0E-14 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 311 4.6E-110 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 Gene3D G3DSA:3.30.1360.10 22 221 1.3E-84 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05305 2fd88388f4e6c1c3b26e34f31d34941c 321 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 30 223 2.9E-24 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_06675 4b3bb6e2e3ae3e027ab350d1e9ccb814 287 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 43 246 2.2E-74 T 14-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 HL41_06675 4b3bb6e2e3ae3e027ab350d1e9ccb814 287 Pfam PF01343 Peptidase family S49 97 248 4.4E-49 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 HL41_06675 4b3bb6e2e3ae3e027ab350d1e9ccb814 287 Gene3D G3DSA:3.40.1750.20 138 204 6.9E-72 T 14-10-2018 HL41_06675 4b3bb6e2e3ae3e027ab350d1e9ccb814 287 Gene3D G3DSA:3.90.226.10 45 242 6.9E-72 T 14-10-2018 HL41_06675 4b3bb6e2e3ae3e027ab350d1e9ccb814 287 PRINTS PR00127 Clp protease catalytic subunit P signature 211 230 2.2E-6 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_06675 4b3bb6e2e3ae3e027ab350d1e9ccb814 287 PRINTS PR00127 Clp protease catalytic subunit P signature 73 93 2.2E-6 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_06675 4b3bb6e2e3ae3e027ab350d1e9ccb814 287 PRINTS PR00127 Clp protease catalytic subunit P signature 105 122 2.2E-6 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_06675 4b3bb6e2e3ae3e027ab350d1e9ccb814 287 SUPERFAMILY SSF52096 21 234 7.82E-43 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 SMART SM01209 100 281 8.4E-4 T 14-10-2018 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 Gene3D G3DSA:3.40.50.20 2 89 1.1E-23 T 14-10-2018 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 Pfam PF07478 D-ala D-ala ligase C-terminus 111 304 1.2E-49 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 7 307 33.736 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 Gene3D G3DSA:3.30.1490.20 116 184 6.4E-70 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 PIRSF PIRSF039102 4 50 1.0E-7 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 PIRSF PIRSF039102 45 311 1.9E-82 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 250 277 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 Pfam PF01820 D-ala D-ala ligase N-terminus 8 90 1.2E-15 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 SUPERFAMILY SSF56059 102 308 2.65E-51 T 14-10-2018 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 Gene3D G3DSA:3.30.470.20 90 303 6.4E-70 T 14-10-2018 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 68 79 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 SUPERFAMILY SSF52440 7 100 1.15E-25 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HL41_01370 f43e7a74a40cbf7249d1bf40478f081b 311 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 8 306 4.1E-88 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_00850 84cb777feff6225bd2f7889d75668529 226 Gene3D G3DSA:3.40.470.10 26 221 4.2E-55 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HL41_00850 84cb777feff6225bd2f7889d75668529 226 SUPERFAMILY SSF52141 43 221 1.9E-48 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HL41_00850 84cb777feff6225bd2f7889d75668529 226 Pfam PF03167 Uracil DNA glycosylase superfamily 68 213 1.7E-33 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HL41_00850 84cb777feff6225bd2f7889d75668529 226 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 53 219 4.6E-47 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 HL41_00850 84cb777feff6225bd2f7889d75668529 226 SMART SM00986 67 213 8.9E-20 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HL41_00850 84cb777feff6225bd2f7889d75668529 226 SMART SM00987 67 213 8.9E-20 T 14-10-2018 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 SMART SM00228 287 370 3.1E-18 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 SMART SM00228 401 483 4.1E-8 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 SUPERFAMILY SSF50494 64 279 9.47E-68 T 14-10-2018 IPR009003 Peptidase S1, PA clan HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 Pfam PF13180 PDZ domain 403 491 3.1E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 Pfam PF13180 PDZ domain 287 378 3.8E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 Gene3D G3DSA:2.40.10.120 62 280 3.9E-84 T 14-10-2018 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 Gene3D G3DSA:2.30.42.10 282 385 5.8E-30 T 14-10-2018 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 SUPERFAMILY SSF50156 402 492 8.94E-17 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 63 488 3.3E-148 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 Gene3D G3DSA:2.30.42.10 401 494 2.8E-19 T 14-10-2018 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 Pfam PF13365 Trypsin-like peptidase domain 114 248 1.2E-32 T 14-10-2018 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 PRINTS PR00834 HtrA/DegQ protease family signature 144 164 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 PRINTS PR00834 HtrA/DegQ protease family signature 241 258 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 PRINTS PR00834 HtrA/DegQ protease family signature 328 340 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 PRINTS PR00834 HtrA/DegQ protease family signature 219 236 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 PRINTS PR00834 HtrA/DegQ protease family signature 123 135 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 PRINTS PR00834 HtrA/DegQ protease family signature 184 208 2.3E-53 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HL41_07475 a03b6333fa9d7835803e84293b8988f9 495 SUPERFAMILY SSF50156 245 370 4.73E-26 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 HL41_05505 bd60e0ebb7d42a5d75bfecd213f63da3 183 Gene3D G3DSA:3.40.140.10 1 171 1.7E-45 T 14-10-2018 HL41_05505 bd60e0ebb7d42a5d75bfecd213f63da3 183 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 81 116 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HL41_05505 bd60e0ebb7d42a5d75bfecd213f63da3 183 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 126 2.4E-25 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain HL41_05505 bd60e0ebb7d42a5d75bfecd213f63da3 183 PIRSF PIRSF006019 1 165 1.6E-50 T 14-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 HL41_05505 bd60e0ebb7d42a5d75bfecd213f63da3 183 SUPERFAMILY SSF53927 7 156 4.42E-37 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 HL41_09065 bafb0936a50c494805462852e7c9236c 442 SMART SM00382 52 331 1.7E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_09065 bafb0936a50c494805462852e7c9236c 442 Gene3D G3DSA:1.10.8.10 113 242 3.6E-108 T 14-10-2018 HL41_09065 bafb0936a50c494805462852e7c9236c 442 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 334 404 3.6E-8 T 14-10-2018 IPR019489 Clp ATPase, C-terminal HL41_09065 bafb0936a50c494805462852e7c9236c 442 SUPERFAMILY SSF52540 7 437 2.34E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_09065 bafb0936a50c494805462852e7c9236c 442 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 4 442 43.369 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 HL41_09065 bafb0936a50c494805462852e7c9236c 442 Gene3D G3DSA:3.40.50.300 9 331 3.6E-108 T 14-10-2018 HL41_09065 bafb0936a50c494805462852e7c9236c 442 Pfam PF07724 AAA domain (Cdc48 subfamily) 190 328 6.1E-40 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HL41_09065 bafb0936a50c494805462852e7c9236c 442 Pfam PF07724 AAA domain (Cdc48 subfamily) 55 119 3.4E-6 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HL41_09065 bafb0936a50c494805462852e7c9236c 442 Gene3D G3DSA:1.10.8.60 334 439 9.9E-41 T 14-10-2018 HL41_09065 bafb0936a50c494805462852e7c9236c 442 SMART SM01086 334 428 7.7E-24 T 14-10-2018 IPR019489 Clp ATPase, C-terminal HL41_09065 bafb0936a50c494805462852e7c9236c 442 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 8 442 3.1E-199 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 HL41_03805 9ddddf58ce605bf06c05f36512b08d28 359 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 64 355 1.5E-102 T 14-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 HL41_03805 9ddddf58ce605bf06c05f36512b08d28 359 SUPERFAMILY SSF102114 28 356 2.62E-51 T 14-10-2018 HL41_03805 9ddddf58ce605bf06c05f36512b08d28 359 PIRSF PIRSF004762 6 359 2.5E-106 T 14-10-2018 HL41_03805 9ddddf58ce605bf06c05f36512b08d28 359 SMART SM00729 67 282 1.2E-7 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_03805 9ddddf58ce605bf06c05f36512b08d28 359 Gene3D G3DSA:3.20.20.70 4 358 4.2E-55 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_03805 9ddddf58ce605bf06c05f36512b08d28 359 Pfam PF04055 Radical SAM superfamily 71 240 1.2E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_03805 9ddddf58ce605bf06c05f36512b08d28 359 Pfam PF13353 4Fe-4S single cluster domain 71 168 1.4E-5 T 14-10-2018 HL41_01850 db284837f1605eee59f92df32a18dffb 933 Gene3D G3DSA:3.90.740.10 194 407 7.1E-252 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HL41_01850 db284837f1605eee59f92df32a18dffb 933 SUPERFAMILY SSF52374 1 650 2.01E-147 T 14-10-2018 HL41_01850 db284837f1605eee59f92df32a18dffb 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 238 261 3.5E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HL41_01850 db284837f1605eee59f92df32a18dffb 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 531 544 3.5E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HL41_01850 db284837f1605eee59f92df32a18dffb 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 400 415 3.5E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HL41_01850 db284837f1605eee59f92df32a18dffb 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 565 574 3.5E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HL41_01850 db284837f1605eee59f92df32a18dffb 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 3.5E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HL41_01850 db284837f1605eee59f92df32a18dffb 933 Gene3D G3DSA:1.10.730.20 644 933 4.6E-88 T 14-10-2018 HL41_01850 db284837f1605eee59f92df32a18dffb 933 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 645 7.0E-205 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_01850 db284837f1605eee59f92df32a18dffb 933 Pfam PF08264 Anticodon-binding domain of tRNA 689 834 9.8E-28 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 HL41_01850 db284837f1605eee59f92df32a18dffb 933 SUPERFAMILY SSF50677 204 402 6.93E-56 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HL41_01850 db284837f1605eee59f92df32a18dffb 933 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 932 20.373 T 14-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 HL41_01850 db284837f1605eee59f92df32a18dffb 933 SUPERFAMILY SSF47323 656 932 4.67E-60 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_01850 db284837f1605eee59f92df32a18dffb 933 Gene3D G3DSA:3.40.50.620 24 633 7.1E-252 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_01850 db284837f1605eee59f92df32a18dffb 933 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 836 1.0E-286 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HL41_01850 db284837f1605eee59f92df32a18dffb 933 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_08925 80a3734e6e231164d1ec2e0b2d7a1001 412 Gene3D G3DSA:3.50.50.60 4 107 6.1E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08925 80a3734e6e231164d1ec2e0b2d7a1001 412 Pfam PF12831 FAD dependent oxidoreductase 5 41 2.1E-8 T 14-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal HL41_08925 80a3734e6e231164d1ec2e0b2d7a1001 412 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 104 115 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08925 80a3734e6e231164d1ec2e0b2d7a1001 412 Gene3D G3DSA:3.50.50.60 270 405 3.4E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08925 80a3734e6e231164d1ec2e0b2d7a1001 412 SUPERFAMILY SSF51905 2 405 7.38E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08925 80a3734e6e231164d1ec2e0b2d7a1001 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 344 360 1.3E-5 T 14-10-2018 HL41_08925 80a3734e6e231164d1ec2e0b2d7a1001 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.3E-5 T 14-10-2018 HL41_01300 249bc55365bb63ba9521ac407e76bda9 168 SUPERFAMILY SSF52255 1 166 2.35E-69 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 HL41_01300 249bc55365bb63ba9521ac407e76bda9 168 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 157 5.3E-70 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HL41_01300 249bc55365bb63ba9521ac407e76bda9 168 PIRSF PIRSF001338 1 161 2.4E-74 T 14-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 HL41_01300 249bc55365bb63ba9521ac407e76bda9 168 SMART SM01001 1 150 4.8E-101 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HL41_01300 249bc55365bb63ba9521ac407e76bda9 168 Pfam PF00731 AIR carboxylase 2 148 1.1E-69 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HL41_01300 249bc55365bb63ba9521ac407e76bda9 168 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 154 34.383 T 14-10-2018 IPR033747 Class I PurE HL41_01300 249bc55365bb63ba9521ac407e76bda9 168 Gene3D G3DSA:3.40.50.7700 1 168 6.0E-80 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 HL41_01720 0501dc6c5861ce06904b1c52ab9feaaa 99 Pfam PF02699 Preprotein translocase subunit 19 94 4.9E-29 T 14-10-2018 IPR003849 Preprotein translocase YajC HL41_01720 0501dc6c5861ce06904b1c52ab9feaaa 99 SMART SM01323 15 97 2.9E-38 T 14-10-2018 IPR003849 Preprotein translocase YajC HL41_01720 0501dc6c5861ce06904b1c52ab9feaaa 99 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 16 94 3.6E-29 T 14-10-2018 IPR003849 Preprotein translocase YajC HL41_01720 0501dc6c5861ce06904b1c52ab9feaaa 99 PRINTS PR01853 Bacterial YajC preprotein translocase signature 37 55 2.1E-16 T 14-10-2018 IPR003849 Preprotein translocase YajC HL41_01720 0501dc6c5861ce06904b1c52ab9feaaa 99 PRINTS PR01853 Bacterial YajC preprotein translocase signature 17 37 2.1E-16 T 14-10-2018 IPR003849 Preprotein translocase YajC HL41_06025 6d36cb6833fcf5bc1a282143ef15a324 714 SUPERFAMILY SSF52540 4 174 3.07E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_06025 6d36cb6833fcf5bc1a282143ef15a324 714 Gene3D G3DSA:3.40.50.300 4 197 1.7E-43 T 14-10-2018 HL41_06025 6d36cb6833fcf5bc1a282143ef15a324 714 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 155 3.8E-14 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_06025 6d36cb6833fcf5bc1a282143ef15a324 714 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 678 2.7E-180 T 14-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HL41_06025 6d36cb6833fcf5bc1a282143ef15a324 714 Pfam PF02421 Ferrous iron transport protein B 4 158 7.6E-62 T 14-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 HL41_06025 6d36cb6833fcf5bc1a282143ef15a324 714 Pfam PF07664 Ferrous iron transport protein B C terminus 457 509 1.1E-20 T 14-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 HL41_06025 6d36cb6833fcf5bc1a282143ef15a324 714 Pfam PF07670 Nucleoside recognition 353 446 1.8E-13 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HL41_06025 6d36cb6833fcf5bc1a282143ef15a324 714 Pfam PF07670 Nucleoside recognition 514 684 3.2E-27 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HL41_05760 3eecaf189159be1539ce4c5525bd4c36 128 Gene3D G3DSA:2.60.120.460 1 127 3.8E-45 T 14-10-2018 IPR035917 YjbQ-like superfamily HL41_05760 3eecaf189159be1539ce4c5525bd4c36 128 PIRSF PIRSF004681 1 128 1.3E-36 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 HL41_05760 3eecaf189159be1539ce4c5525bd4c36 128 Pfam PF01894 Uncharacterised protein family UPF0047 17 124 7.4E-35 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 HL41_05760 3eecaf189159be1539ce4c5525bd4c36 128 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 90 108 - T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 HL41_05760 3eecaf189159be1539ce4c5525bd4c36 128 SUPERFAMILY SSF111038 3 126 8.11E-42 T 14-10-2018 IPR035917 YjbQ-like superfamily HL41_05760 3eecaf189159be1539ce4c5525bd4c36 128 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 125 2.5E-43 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 HL41_06510 92ff1b2aa3e2b6998644c9119e734d51 422 Gene3D G3DSA:3.40.605.10 23 416 5.5E-170 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 HL41_06510 92ff1b2aa3e2b6998644c9119e734d51 422 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 10 421 42.416 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HL41_06510 92ff1b2aa3e2b6998644c9119e734d51 422 Pfam PF00171 Aldehyde dehydrogenase family 8 291 1.3E-19 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 HL41_06510 92ff1b2aa3e2b6998644c9119e734d51 422 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 18 411 8.2E-148 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HL41_06510 92ff1b2aa3e2b6998644c9119e734d51 422 PIRSF PIRSF000151 4 422 4.9E-182 T 14-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 HL41_06510 92ff1b2aa3e2b6998644c9119e734d51 422 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 328 349 - T 14-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HL41_06510 92ff1b2aa3e2b6998644c9119e734d51 422 Gene3D G3DSA:3.40.309.10 231 379 5.5E-170 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 HL41_06510 92ff1b2aa3e2b6998644c9119e734d51 422 SUPERFAMILY SSF53720 11 421 1.18E-123 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HL41_02385 940277ed016a17ad2752565b9beaf265 345 SUPERFAMILY SSF102114 5 315 4.58E-44 T 14-10-2018 HL41_02385 940277ed016a17ad2752565b9beaf265 345 SMART SM00729 4 207 0.0055 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_02385 940277ed016a17ad2752565b9beaf265 345 Pfam PF13394 4Fe-4S single cluster domain 11 91 8.2E-8 T 14-10-2018 HL41_02385 940277ed016a17ad2752565b9beaf265 345 Pfam PF13186 Iron-sulfur cluster-binding domain 232 310 2.9E-12 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain HL41_02385 940277ed016a17ad2752565b9beaf265 345 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 4 345 4.0E-121 T 14-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase HL41_02385 940277ed016a17ad2752565b9beaf265 345 Gene3D G3DSA:3.20.20.70 2 300 1.2E-42 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_02385 940277ed016a17ad2752565b9beaf265 345 Pfam PF04055 Radical SAM superfamily 9 166 5.8E-13 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_03845 42691757b3a3b28bc5ab10917ddd6482 426 Gene3D G3DSA:2.40.160.60 23 426 5.2E-143 T 14-10-2018 HL41_03845 42691757b3a3b28bc5ab10917ddd6482 426 SUPERFAMILY SSF56935 23 426 1.37E-95 T 14-10-2018 HL41_03845 42691757b3a3b28bc5ab10917ddd6482 426 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 20 426 1.4E-114 T 14-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) HL41_03160 8d492db48324ecb231997f4d606b2c87 326 Gene3D G3DSA:3.90.1640.10 2 200 1.9E-48 T 14-10-2018 HL41_03160 8d492db48324ecb231997f4d606b2c87 326 Pfam PF02272 DHHA1 domain 202 319 1.1E-14 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HL41_03160 8d492db48324ecb231997f4d606b2c87 326 Gene3D G3DSA:3.10.310.30 201 314 4.0E-20 T 14-10-2018 HL41_03160 8d492db48324ecb231997f4d606b2c87 326 Pfam PF01368 DHH family 17 160 1.5E-12 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HL41_03160 8d492db48324ecb231997f4d606b2c87 326 SUPERFAMILY SSF64182 15 314 3.14E-59 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily HL41_05920 792a77be9494deef20ba25be6aa9db88 396 Gene3D G3DSA:3.60.15.10 1 245 1.6E-96 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_05920 792a77be9494deef20ba25be6aa9db88 396 Gene3D G3DSA:3.40.50.360 247 396 2.1E-43 T 14-10-2018 IPR029039 Flavoprotein-like superfamily HL41_05920 792a77be9494deef20ba25be6aa9db88 396 Pfam PF00753 Metallo-beta-lactamase superfamily 34 225 3.4E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_05920 792a77be9494deef20ba25be6aa9db88 396 Pfam PF00258 Flavodoxin 254 377 5.5E-13 T 14-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 HL41_05920 792a77be9494deef20ba25be6aa9db88 396 SMART SM00849 33 225 1.3E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_05920 792a77be9494deef20ba25be6aa9db88 396 PIRSF PIRSF005243 1 396 5.9E-154 T 14-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 HL41_05920 792a77be9494deef20ba25be6aa9db88 396 SUPERFAMILY SSF52218 250 395 9.58E-38 T 14-10-2018 IPR029039 Flavoprotein-like superfamily HL41_05920 792a77be9494deef20ba25be6aa9db88 396 SUPERFAMILY SSF56281 9 281 4.06E-49 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_06940 124b603775b1daef99d2d55ff0b029e4 294 Pfam PF13401 AAA domain 97 215 3.8E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_06940 124b603775b1daef99d2d55ff0b029e4 294 SMART SM00382 97 234 1.1E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_06940 124b603775b1daef99d2d55ff0b029e4 294 Gene3D G3DSA:3.40.50.300 79 229 4.2E-11 T 14-10-2018 HL41_06940 124b603775b1daef99d2d55ff0b029e4 294 SUPERFAMILY SSF52540 63 277 7.12E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07465 adfe3a4004ba6005af4a3c1432d638a3 252 Pfam PF02565 Recombination protein O C terminal 85 200 3.0E-11 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HL41_07465 adfe3a4004ba6005af4a3c1432d638a3 252 SUPERFAMILY SSF50249 1 76 5.65E-11 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_07465 adfe3a4004ba6005af4a3c1432d638a3 252 Gene3D G3DSA:3.30.60.100 147 185 6.1E-11 T 14-10-2018 HL41_07465 adfe3a4004ba6005af4a3c1432d638a3 252 Pfam PF11967 Recombination protein O N terminal 1 76 2.7E-13 T 14-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal HL41_07465 adfe3a4004ba6005af4a3c1432d638a3 252 Gene3D G3DSA:2.40.50.140 2 78 1.0E-11 T 14-10-2018 HL41_07465 adfe3a4004ba6005af4a3c1432d638a3 252 Hamap MF_00201 DNA repair protein RecO [recO]. 1 249 19.54 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HL41_07465 adfe3a4004ba6005af4a3c1432d638a3 252 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 209 9.3E-29 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HL41_07465 adfe3a4004ba6005af4a3c1432d638a3 252 SUPERFAMILY SSF57863 82 205 6.28E-18 T 14-10-2018 IPR037278 ARFGAP/RecO-like zinc finger HL41_07465 adfe3a4004ba6005af4a3c1432d638a3 252 Gene3D G3DSA:1.20.1440.120 87 232 6.1E-11 T 14-10-2018 HL41_05415 d964737361f9a73b97df289dca040d86 220 ProSitePatterns PS00548 Ribosomal protein S3 signature. 164 198 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05415 d964737361f9a73b97df289dca040d86 220 Gene3D G3DSA:3.30.300.20 17 108 7.0E-31 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta HL41_05415 d964737361f9a73b97df289dca040d86 220 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 210 1.6E-94 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HL41_05415 d964737361f9a73b97df289dca040d86 220 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 207 38.884 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HL41_05415 d964737361f9a73b97df289dca040d86 220 SUPERFAMILY SSF54821 109 207 5.1E-41 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05415 d964737361f9a73b97df289dca040d86 220 SMART SM00322 60 126 7.1E-8 T 14-10-2018 IPR004087 K Homology domain GO:0003676 HL41_05415 d964737361f9a73b97df289dca040d86 220 Gene3D G3DSA:3.30.1140.32 109 209 2.3E-43 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05415 d964737361f9a73b97df289dca040d86 220 Pfam PF07650 KH domain 39 112 2.3E-18 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05415 d964737361f9a73b97df289dca040d86 220 Pfam PF00189 Ribosomal protein S3, C-terminal domain 121 203 1.1E-38 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05415 d964737361f9a73b97df289dca040d86 220 SUPERFAMILY SSF54814 2 100 7.06E-37 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HL41_03780 2a043515e08454234a9994d7b34bb357 284 SUPERFAMILY SSF53613 95 281 1.56E-22 T 14-10-2018 IPR029056 Ribokinase-like HL41_03780 2a043515e08454234a9994d7b34bb357 284 Gene3D G3DSA:3.40.1190.20 99 283 6.5E-19 T 14-10-2018 IPR029056 Ribokinase-like HL41_03780 2a043515e08454234a9994d7b34bb357 284 Pfam PF01256 Carbohydrate kinase 115 266 8.2E-11 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 HL41_03780 2a043515e08454234a9994d7b34bb357 284 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 222 232 - T 14-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site HL41_04570 e9c42cb2a6a7f99bc06f17511ef50057 245 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 59 72 - T 14-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_04570 e9c42cb2a6a7f99bc06f17511ef50057 245 SUPERFAMILY SSF51366 2 235 2.8E-65 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HL41_04570 e9c42cb2a6a7f99bc06f17511ef50057 245 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 223 1.1E-40 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_04570 e9c42cb2a6a7f99bc06f17511ef50057 245 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 4 232 32.807 T 14-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_04570 e9c42cb2a6a7f99bc06f17511ef50057 245 Gene3D G3DSA:3.20.20.70 3 240 2.2E-76 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_04570 e9c42cb2a6a7f99bc06f17511ef50057 245 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 8 227 1.2E-52 T 14-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_04570 e9c42cb2a6a7f99bc06f17511ef50057 245 SMART SM00934 6 227 2.5E-79 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_00845 e75a671edcf384eb3c9e1d30b15f88a4 429 SUPERFAMILY SSF141322 360 426 9.68E-18 T 14-10-2018 HL41_00845 e75a671edcf384eb3c9e1d30b15f88a4 429 Gene3D G3DSA:3.90.226.10 23 241 3.2E-56 T 14-10-2018 HL41_00845 e75a671edcf384eb3c9e1d30b15f88a4 429 SUPERFAMILY SSF52096 8 188 1.8E-22 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HL41_00845 e75a671edcf384eb3c9e1d30b15f88a4 429 Gene3D G3DSA:2.40.50.140 364 429 1.1E-17 T 14-10-2018 HL41_00845 e75a671edcf384eb3c9e1d30b15f88a4 429 Pfam PF00574 Clp protease 51 188 5.1E-5 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HL41_00845 e75a671edcf384eb3c9e1d30b15f88a4 429 Pfam PF01957 NfeD-like C-terminal, partner-binding 290 427 3.5E-30 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain HL41_04525 fc2150439aad4846d29236654bd9070a 160 Pfam PF00578 AhpC/TSA family 27 137 2.2E-7 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HL41_04525 fc2150439aad4846d29236654bd9070a 160 ProSitePatterns PS00194 Thioredoxin family active site. 49 67 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 HL41_04525 fc2150439aad4846d29236654bd9070a 160 Gene3D G3DSA:3.40.30.10 23 158 1.2E-20 T 14-10-2018 HL41_04525 fc2150439aad4846d29236654bd9070a 160 SUPERFAMILY SSF52833 4 156 8.65E-20 T 14-10-2018 IPR036249 Thioredoxin-like superfamily HL41_06225 f49c0388bdc439a1b95ed427238f30c0 275 SUPERFAMILY SSF53850 6 261 5.74E-61 T 14-10-2018 HL41_06225 f49c0388bdc439a1b95ed427238f30c0 275 Gene3D G3DSA:3.40.190.10 8 258 5.6E-83 T 14-10-2018 HL41_06225 f49c0388bdc439a1b95ed427238f30c0 275 Gene3D G3DSA:3.40.190.10 82 177 5.6E-83 T 14-10-2018 HL41_06225 f49c0388bdc439a1b95ed427238f30c0 275 Pfam PF02621 Menaquinone biosynthesis 6 261 8.7E-63 T 14-10-2018 IPR003773 Menaquinone biosynthesis enzyme HL41_06225 f49c0388bdc439a1b95ed427238f30c0 275 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 5 269 33.423 T 14-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 HL41_05385 5b09dc24f5511f02e9994427b1e74f71 179 SUPERFAMILY SSF55282 4 178 9.89E-75 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05385 5b09dc24f5511f02e9994427b1e74f71 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 42.041 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05385 5b09dc24f5511f02e9994427b1e74f71 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 4.7E-39 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05385 5b09dc24f5511f02e9994427b1e74f71 179 Gene3D G3DSA:3.30.1440.10 2 178 5.2E-79 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05385 5b09dc24f5511f02e9994427b1e74f71 179 Pfam PF00281 Ribosomal protein L5 24 80 4.0E-24 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05385 5b09dc24f5511f02e9994427b1e74f71 179 PIRSF PIRSF002161 1 179 1.9E-64 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_02520 553450fcc13cfbffb462735c94b3d9d0 312 SUPERFAMILY SSF48179 181 309 8.84E-30 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HL41_02520 553450fcc13cfbffb462735c94b3d9d0 312 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 310 8.1E-76 T 14-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 HL41_02520 553450fcc13cfbffb462735c94b3d9d0 312 Gene3D G3DSA:3.40.50.720 1 180 1.8E-37 T 14-10-2018 HL41_02520 553450fcc13cfbffb462735c94b3d9d0 312 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 182 308 3.6E-32 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain HL41_02520 553450fcc13cfbffb462735c94b3d9d0 312 Gene3D G3DSA:1.10.1040.10 181 312 1.4E-38 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HL41_02520 553450fcc13cfbffb462735c94b3d9d0 312 SUPERFAMILY SSF51735 1 173 5.26E-16 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_02520 553450fcc13cfbffb462735c94b3d9d0 312 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 152 2.1E-27 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 Pfam PF00742 Homoserine dehydrogenase 137 315 1.3E-65 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 SUPERFAMILY SSF55347 137 302 6.02E-54 T 14-10-2018 HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 SUPERFAMILY SSF51735 1 158 2.63E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 PIRSF PIRSF000098 1 433 1.2E-162 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 SUPERFAMILY SSF55021 352 421 1.91E-12 T 14-10-2018 HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 Gene3D G3DSA:3.40.50.720 4 341 8.7E-163 T 14-10-2018 HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 Gene3D G3DSA:3.30.360.10 136 346 8.7E-163 T 14-10-2018 HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 Pfam PF01842 ACT domain 352 419 6.6E-13 T 14-10-2018 IPR002912 ACT domain HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 121 1.5E-14 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 HL41_01465 23e66db1bbc322084a52b62cb47ca34c 434 Gene3D G3DSA:3.30.70.260 347 421 8.7E-163 T 14-10-2018 HL41_06040 3bcb75d22549067a86da0231abe1be9e 239 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 81 236 3.1E-40 T 14-10-2018 IPR000160 GGDEF domain HL41_06040 3bcb75d22549067a86da0231abe1be9e 239 Gene3D G3DSA:2.30.30.90 1 73 1.4E-11 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain HL41_06040 3bcb75d22549067a86da0231abe1be9e 239 Pfam PF00990 Diguanylate cyclase, GGDEF domain 82 232 2.9E-39 T 14-10-2018 IPR000160 GGDEF domain HL41_06040 3bcb75d22549067a86da0231abe1be9e 239 Pfam PF04023 FeoA domain 1 70 7.3E-12 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HL41_06040 3bcb75d22549067a86da0231abe1be9e 239 SMART SM00267 71 237 2.0E-50 T 14-10-2018 IPR000160 GGDEF domain HL41_06040 3bcb75d22549067a86da0231abe1be9e 239 Gene3D G3DSA:3.30.70.270 76 238 5.2E-47 T 14-10-2018 HL41_06040 3bcb75d22549067a86da0231abe1be9e 239 SMART SM00899 4 70 1.7E-7 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HL41_06040 3bcb75d22549067a86da0231abe1be9e 239 SUPERFAMILY SSF55073 87 237 8.63E-41 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_06040 3bcb75d22549067a86da0231abe1be9e 239 SUPERFAMILY SSF50037 1 70 1.33E-10 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal HL41_07470 fffc77595f1eb313954733a4519b3413 310 Gene3D G3DSA:3.10.50.40 177 270 2.3E-35 T 14-10-2018 HL41_07470 fffc77595f1eb313954733a4519b3413 310 Gene3D G3DSA:1.10.4030.30 32 303 2.3E-35 T 14-10-2018 HL41_07470 fffc77595f1eb313954733a4519b3413 310 Pfam PF13624 SurA N-terminal domain 3 148 1.3E-15 T 14-10-2018 HL41_07470 fffc77595f1eb313954733a4519b3413 310 SUPERFAMILY SSF54534 183 265 2.62E-5 T 14-10-2018 HL41_07470 fffc77595f1eb313954733a4519b3413 310 Pfam PF13145 PPIC-type PPIASE domain 159 277 2.7E-12 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 HL41_07470 fffc77595f1eb313954733a4519b3413 310 SUPERFAMILY SSF109998 29 205 2.16E-27 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily HL41_08995 1a87c35bd794b726522be2fa461a8eec 130 TIGRFAM TIGR00855 L12: ribosomal protein bL12 3 130 1.5E-50 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08995 1a87c35bd794b726522be2fa461a8eec 130 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 64 130 1.5E-33 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08995 1a87c35bd794b726522be2fa461a8eec 130 Gene3D G3DSA:3.30.1390.10 60 130 2.7E-34 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HL41_08995 1a87c35bd794b726522be2fa461a8eec 130 SUPERFAMILY SSF48300 4 66 3.66E-15 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08995 1a87c35bd794b726522be2fa461a8eec 130 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 51 3.8E-19 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08995 1a87c35bd794b726522be2fa461a8eec 130 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 66 130 2.0E-21 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08995 1a87c35bd794b726522be2fa461a8eec 130 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 130 26.626 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08995 1a87c35bd794b726522be2fa461a8eec 130 SUPERFAMILY SSF54736 59 130 8.37E-27 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HL41_08995 1a87c35bd794b726522be2fa461a8eec 130 Gene3D G3DSA:1.20.5.710 3 59 5.3E-20 T 14-10-2018 HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 SUPERFAMILY SSF51246 336 452 4.5E-34 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 Gene3D G3DSA:3.30.470.130 1 454 1.7E-182 T 14-10-2018 HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 SUPERFAMILY SSF52440 2 115 6.62E-47 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 326 1.1E-68 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 SMART SM00878 340 446 1.5E-48 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 SUPERFAMILY SSF56059 85 351 3.7E-67 T 14-10-2018 HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 6.5E-43 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 Pfam PF02785 Biotin carboxylase C-terminal domain 340 447 1.1E-33 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HL41_00430 ce2f9abffe0755887da5819974e43ef8 484 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_06545 f3264d72e0c7909ecf064d4e16dea56d 135 SUPERFAMILY SSF52402 1 133 2.15E-24 T 14-10-2018 HL41_06545 f3264d72e0c7909ecf064d4e16dea56d 135 Pfam PF00582 Universal stress protein family 2 132 4.1E-23 T 14-10-2018 IPR006016 UspA HL41_06545 f3264d72e0c7909ecf064d4e16dea56d 135 Gene3D G3DSA:3.40.50.620 1 134 3.8E-27 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_02350 b7424028a586507ce22ffede0b007251 240 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 227 8.5E-73 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 HL41_02350 b7424028a586507ce22ffede0b007251 240 Gene3D G3DSA:3.30.160.20 160 227 1.2E-25 T 14-10-2018 HL41_02350 b7424028a586507ce22ffede0b007251 240 SMART SM00358 161 228 5.8E-27 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain HL41_02350 b7424028a586507ce22ffede0b007251 240 SMART SM00535 20 155 2.5E-45 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 HL41_02350 b7424028a586507ce22ffede0b007251 240 SUPERFAMILY SSF54768 116 232 4.24E-25 T 14-10-2018 HL41_02350 b7424028a586507ce22ffede0b007251 240 ProSitePatterns PS00517 Ribonuclease III family signature. 44 52 - T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 HL41_02350 b7424028a586507ce22ffede0b007251 240 SUPERFAMILY SSF69065 3 163 2.96E-43 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 HL41_02350 b7424028a586507ce22ffede0b007251 240 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 224 28.988 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 HL41_02350 b7424028a586507ce22ffede0b007251 240 Pfam PF00035 Double-stranded RNA binding motif 161 227 3.5E-22 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain HL41_02350 b7424028a586507ce22ffede0b007251 240 Pfam PF14622 Ribonuclease-III-like 18 146 3.9E-35 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 HL41_02350 b7424028a586507ce22ffede0b007251 240 Gene3D G3DSA:1.10.1520.10 4 151 3.2E-43 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 HL41_01150 3ce926342f9eb8ea1472762838fbf896 281 Gene3D G3DSA:3.20.20.70 124 270 1.6E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_01150 3ce926342f9eb8ea1472762838fbf896 281 SUPERFAMILY SSF54675 5 109 4.12E-28 T 14-10-2018 HL41_01150 3ce926342f9eb8ea1472762838fbf896 281 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 110 279 8.7E-58 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 HL41_01150 3ce926342f9eb8ea1472762838fbf896 281 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 19 108 1.2E-23 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 HL41_01150 3ce926342f9eb8ea1472762838fbf896 281 Gene3D G3DSA:3.90.1170.20 14 278 1.6E-95 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 HL41_01150 3ce926342f9eb8ea1472762838fbf896 281 PIRSF PIRSF006250 1 281 4.4E-91 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 HL41_01150 3ce926342f9eb8ea1472762838fbf896 281 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 11 280 1.8E-90 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 HL41_01150 3ce926342f9eb8ea1472762838fbf896 281 SUPERFAMILY SSF51690 110 280 1.88E-54 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 HL41_05740 982a95befa4642cb95359badea81d9e4 242 SMART SM00650 16 180 3.2E-50 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 HL41_05740 982a95befa4642cb95359badea81d9e4 242 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 239 1.8E-43 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm HL41_05740 982a95befa4642cb95359badea81d9e4 242 Gene3D G3DSA:1.10.8.100 182 242 1.1E-14 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 HL41_05740 982a95befa4642cb95359badea81d9e4 242 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 31 59 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 HL41_05740 982a95befa4642cb95359badea81d9e4 242 SUPERFAMILY SSF53335 2 240 8.52E-54 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_05740 982a95befa4642cb95359badea81d9e4 242 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 2 238 7.4E-63 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HL41_05740 982a95befa4642cb95359badea81d9e4 242 Gene3D G3DSA:3.40.50.150 1 180 9.7E-52 T 14-10-2018 HL41_05740 982a95befa4642cb95359badea81d9e4 242 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 1 241 39.882 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 Gene3D G3DSA:3.40.50.620 3 164 5.0E-60 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 Pfam PF01467 Cytidylyltransferase-like 8 140 7.1E-22 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 65 2.2E-20 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 SUPERFAMILY SSF52374 4 162 1.42E-46 T 14-10-2018 HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 5 164 36.175 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 7 163 3.6E-61 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 23 44 1.3E-39 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 118 140 1.3E-39 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 91 107 1.3E-39 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HL41_01660 27bbf4a421b72393c575900f68e78e7e 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 5 23 1.3E-39 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 Gene3D G3DSA:3.40.50.720 1 199 1.4E-76 T 14-10-2018 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 293 1.8E-39 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 Gene3D G3DSA:1.20.5.100 200 231 3.1E-18 T 14-10-2018 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 183 3.0E-66 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 SUPERFAMILY SSF48179 201 298 1.22E-34 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 SUPERFAMILY SSF51735 1 188 7.71E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 SMART SM00984 316 419 1.2E-42 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 419 2.2E-31 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 Gene3D G3DSA:3.40.50.720 232 435 2.9E-77 T 14-10-2018 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 PIRSF PIRSF500134 1 435 1.4E-181 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 PIRSF PIRSF000124 1 434 5.2E-154 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 415 7.4E-146 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HL41_01970 8bb568f41aed11f066a6dc23646bf592 435 SUPERFAMILY SSF52413 302 429 2.62E-36 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 HL41_00695 7a59d3810b53ce0cbc68485330c2cfcb 92 SUPERFAMILY SSF47729 1 90 5.15E-31 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 HL41_00695 7a59d3810b53ce0cbc68485330c2cfcb 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.5E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HL41_00695 7a59d3810b53ce0cbc68485330c2cfcb 92 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.5E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HL41_00695 7a59d3810b53ce0cbc68485330c2cfcb 92 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.5E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HL41_00695 7a59d3810b53ce0cbc68485330c2cfcb 92 Pfam PF00216 Bacterial DNA-binding protein 1 88 5.8E-34 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HL41_00695 7a59d3810b53ce0cbc68485330c2cfcb 92 SMART SM00411 1 90 6.8E-35 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HL41_00695 7a59d3810b53ce0cbc68485330c2cfcb 92 Gene3D G3DSA:4.10.520.10 1 92 6.1E-35 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 HL41_00695 7a59d3810b53ce0cbc68485330c2cfcb 92 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 HL41_06685 c01f044692c6395d51271c0d5bc40420 401 Pfam PF00872 Transposase, Mutator family 6 357 2.2E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_06345 c01f044692c6395d51271c0d5bc40420 401 Pfam PF00872 Transposase, Mutator family 6 357 2.2E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_08415 c01f044692c6395d51271c0d5bc40420 401 Pfam PF00872 Transposase, Mutator family 6 357 2.2E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_04380 c01f044692c6395d51271c0d5bc40420 401 Pfam PF00872 Transposase, Mutator family 6 357 2.2E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_03065 c01f044692c6395d51271c0d5bc40420 401 Pfam PF00872 Transposase, Mutator family 6 357 2.2E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_05570 c01f044692c6395d51271c0d5bc40420 401 Pfam PF00872 Transposase, Mutator family 6 357 2.2E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_09190 c01f044692c6395d51271c0d5bc40420 401 Pfam PF00872 Transposase, Mutator family 6 357 2.2E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_06695 c01f044692c6395d51271c0d5bc40420 401 Pfam PF00872 Transposase, Mutator family 6 357 2.2E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_03500 7206a12f24f081ddee88c07620815d69 400 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 397 53.444 T 14-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HL41_03500 7206a12f24f081ddee88c07620815d69 400 SUPERFAMILY SSF52402 3 166 1.01E-47 T 14-10-2018 HL41_03500 7206a12f24f081ddee88c07620815d69 400 Pfam PF00764 Arginosuccinate synthase 6 392 2.3E-171 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HL41_03500 7206a12f24f081ddee88c07620815d69 400 SUPERFAMILY SSF69864 171 396 4.58E-99 T 14-10-2018 HL41_03500 7206a12f24f081ddee88c07620815d69 400 Gene3D G3DSA:3.40.50.620 3 173 1.4E-70 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_03500 7206a12f24f081ddee88c07620815d69 400 Gene3D G3DSA:3.90.1260.10 174 400 1.6E-108 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HL41_03500 7206a12f24f081ddee88c07620815d69 400 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HL41_03500 7206a12f24f081ddee88c07620815d69 400 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 394 6.2E-163 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HL41_03500 7206a12f24f081ddee88c07620815d69 400 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HL41_04830 27d4f41750199d5a96b4302444babbd7 286 SUPERFAMILY SSF81799 112 208 5.23E-22 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 HL41_04830 27d4f41750199d5a96b4302444babbd7 286 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 285 2.8E-84 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 HL41_04830 27d4f41750199d5a96b4302444babbd7 286 Gene3D G3DSA:1.10.150.170 110 209 5.4E-91 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 HL41_04830 27d4f41750199d5a96b4302444babbd7 286 Gene3D G3DSA:3.40.50.150 7 285 5.4E-91 T 14-10-2018 HL41_04830 27d4f41750199d5a96b4302444babbd7 286 SUPERFAMILY SSF53335 3 286 5.63E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_04830 27d4f41750199d5a96b4302444babbd7 286 Pfam PF01795 MraW methylase family 3 286 1.2E-87 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 HL41_04830 27d4f41750199d5a96b4302444babbd7 286 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 286 32.266 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 HL41_04830 27d4f41750199d5a96b4302444babbd7 286 PIRSF PIRSF004486 1 286 6.7E-93 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 HL41_06670 7ddda9531b899301c86ce03db40dfbbf 398 Gene3D G3DSA:3.30.420.40 95 214 4.6E-29 T 14-10-2018 HL41_06670 7ddda9531b899301c86ce03db40dfbbf 398 SMART SM00411 1 93 6.5E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HL41_06670 7ddda9531b899301c86ce03db40dfbbf 398 Pfam PF02541 Ppx/GppA phosphatase family 119 395 4.6E-51 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 HL41_06670 7ddda9531b899301c86ce03db40dfbbf 398 SUPERFAMILY SSF47729 1 93 1.62E-18 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 HL41_06670 7ddda9531b899301c86ce03db40dfbbf 398 Pfam PF00216 Bacterial DNA-binding protein 1 93 1.2E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HL41_06670 7ddda9531b899301c86ce03db40dfbbf 398 Gene3D G3DSA:3.30.420.150 221 397 1.1E-39 T 14-10-2018 HL41_06670 7ddda9531b899301c86ce03db40dfbbf 398 SUPERFAMILY SSF53067 223 397 7.47E-33 T 14-10-2018 HL41_06670 7ddda9531b899301c86ce03db40dfbbf 398 Gene3D G3DSA:4.10.520.10 1 94 1.1E-21 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 HL41_06670 7ddda9531b899301c86ce03db40dfbbf 398 SUPERFAMILY SSF53067 96 214 1.79E-25 T 14-10-2018 HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 SUPERFAMILY SSF55785 312 420 3.84E-10 T 14-10-2018 IPR035965 PAS domain superfamily HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 SMART SM00091 12 76 6.6E-6 T 14-10-2018 IPR000014 PAS domain HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 SMART SM00091 300 371 1.8 T 14-10-2018 IPR000014 PAS domain HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Gene3D G3DSA:3.30.70.270 417 592 4.2E-32 T 14-10-2018 HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Gene3D G3DSA:3.30.450.40 134 296 1.7E-26 T 14-10-2018 IPR029016 GAF-like domain superfamily HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 306 415 4.0E-6 T 14-10-2018 IPR000014 PAS domain HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 129 1.5E-17 T 14-10-2018 IPR000014 PAS domain HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Gene3D G3DSA:3.20.20.450 593 830 3.4E-71 T 14-10-2018 IPR035919 EAL domain superfamily HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Pfam PF00563 EAL domain 598 819 3.1E-59 T 14-10-2018 IPR001633 EAL domain HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Pfam PF13426 PAS domain 310 411 3.5E-9 T 14-10-2018 IPR000014 PAS domain HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 SMART SM00052 590 824 3.4E-69 T 14-10-2018 IPR001633 EAL domain HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Pfam PF13185 GAF domain 145 290 5.7E-20 T 14-10-2018 IPR003018 GAF domain GO:0005515 HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Pfam PF00990 Diguanylate cyclase, GGDEF domain 426 574 7.7E-22 T 14-10-2018 IPR000160 GGDEF domain HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Gene3D G3DSA:3.30.450.20 308 409 6.5E-10 T 14-10-2018 HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 SUPERFAMILY SSF55785 18 126 9.07E-17 T 14-10-2018 IPR035965 PAS domain superfamily HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 SMART SM00267 412 580 6.9E-20 T 14-10-2018 IPR000160 GGDEF domain HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 SUPERFAMILY SSF55073 428 581 1.18E-27 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Gene3D G3DSA:3.30.450.20 22 133 6.5E-15 T 14-10-2018 HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 SUPERFAMILY SSF55781 121 290 4.8E-24 T 14-10-2018 HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 SUPERFAMILY SSF141868 597 831 2.35E-66 T 14-10-2018 IPR035919 EAL domain superfamily HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 Pfam PF08447 PAS fold 32 116 8.5E-9 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 HL41_03225 fc74dd3373845339bbe75b1e40518b48 840 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 419 576 2.9E-19 T 14-10-2018 IPR000160 GGDEF domain HL41_01570 00854e8967e258cde6a71ca03b015822 220 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 3 209 1.7E-54 T 14-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 HL41_01570 00854e8967e258cde6a71ca03b015822 220 SUPERFAMILY SSF53597 1 210 1.36E-52 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 HL41_01570 00854e8967e258cde6a71ca03b015822 220 Pfam PF01872 RibD C-terminal domain 4 209 1.7E-52 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 HL41_01570 00854e8967e258cde6a71ca03b015822 220 TIGRFAM TIGR01508 rib_reduct_arch: diaminohydroxyphosphoribosylaminopyrimidine reductase 4 210 1.0E-57 T 14-10-2018 IPR006401 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal GO:0016491|GO:0055114 KEGG: 00740+1.1.1.302|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_01570 00854e8967e258cde6a71ca03b015822 220 Gene3D G3DSA:3.40.430.10 1 218 1.3E-56 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 HL41_02515 01d7f5230cd85b97d37f5b9a82116da5 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 2.2E-17 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HL41_02515 01d7f5230cd85b97d37f5b9a82116da5 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 2.2E-17 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HL41_02515 01d7f5230cd85b97d37f5b9a82116da5 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 38 2.2E-17 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HL41_02515 01d7f5230cd85b97d37f5b9a82116da5 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 2.2E-17 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HL41_02515 01d7f5230cd85b97d37f5b9a82116da5 112 SUPERFAMILY SSF46785 1 82 1.26E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_02515 01d7f5230cd85b97d37f5b9a82116da5 112 SMART SM00418 6 86 2.2E-21 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HL41_02515 01d7f5230cd85b97d37f5b9a82116da5 112 Pfam PF01022 Bacterial regulatory protein, arsR family 13 56 2.5E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HL41_02515 01d7f5230cd85b97d37f5b9a82116da5 112 Gene3D G3DSA:1.10.10.10 1 94 1.4E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_03000 e0343a93a15e6750c8b9435dd30a4ec6 153 SUPERFAMILY SSF102405 6 150 7.63E-34 T 14-10-2018 HL41_03000 e0343a93a15e6750c8b9435dd30a4ec6 153 TIGRFAM TIGR00725 TIGR00725: TIGR00725 family protein 7 126 6.7E-40 T 14-10-2018 IPR005268 Conserved hypothetical protein CHP00725 HL41_03000 e0343a93a15e6750c8b9435dd30a4ec6 153 Gene3D G3DSA:3.40.50.450 1 152 1.4E-40 T 14-10-2018 HL41_03000 e0343a93a15e6750c8b9435dd30a4ec6 153 Pfam PF03641 Possible lysine decarboxylase 47 117 2.7E-10 T 14-10-2018 IPR031100 LOG family HL41_01285 2308794f868734d791d4f153125f80c3 735 SMART SM00471 41 160 8.4E-10 T 14-10-2018 IPR003607 HD/PDEase domain HL41_01285 2308794f868734d791d4f153125f80c3 735 Gene3D G3DSA:3.30.70.260 656 734 1.5E-20 T 14-10-2018 HL41_01285 2308794f868734d791d4f153125f80c3 735 SUPERFAMILY SSF81301 188 402 8.5E-61 T 14-10-2018 HL41_01285 2308794f868734d791d4f153125f80c3 735 Gene3D G3DSA:1.10.3210.10 1 197 1.3E-79 T 14-10-2018 HL41_01285 2308794f868734d791d4f153125f80c3 735 Pfam PF04607 Region found in RelA / SpoT proteins 242 354 2.0E-34 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 HL41_01285 2308794f868734d791d4f153125f80c3 735 SUPERFAMILY SSF81271 385 457 1.01E-24 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HL41_01285 2308794f868734d791d4f153125f80c3 735 SUPERFAMILY SSF55021 655 732 3.82E-12 T 14-10-2018 HL41_01285 2308794f868734d791d4f153125f80c3 735 Gene3D G3DSA:3.10.20.30 391 466 7.5E-33 T 14-10-2018 IPR012675 Beta-grasp domain superfamily HL41_01285 2308794f868734d791d4f153125f80c3 735 Pfam PF13328 HD domain 26 182 7.6E-55 T 14-10-2018 IPR003607 HD/PDEase domain HL41_01285 2308794f868734d791d4f153125f80c3 735 Pfam PF13291 ACT domain 655 732 1.6E-19 T 14-10-2018 IPR002912 ACT domain HL41_01285 2308794f868734d791d4f153125f80c3 735 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 731 1.8E-239 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 HL41_01285 2308794f868734d791d4f153125f80c3 735 SMART SM00954 242 355 3.2E-58 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 HL41_01285 2308794f868734d791d4f153125f80c3 735 SUPERFAMILY SSF109604 3 198 2.35E-72 T 14-10-2018 HL41_01285 2308794f868734d791d4f153125f80c3 735 Gene3D G3DSA:3.30.460.10 200 335 2.2E-48 T 14-10-2018 HL41_01285 2308794f868734d791d4f153125f80c3 735 Pfam PF02824 TGS domain 398 455 5.3E-21 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 HL41_03720 ad26e0d079e22573053111fe81337334 424 SUPERFAMILY SSF56801 37 381 5.1E-54 T 14-10-2018 HL41_03720 ad26e0d079e22573053111fe81337334 424 Pfam PF00501 AMP-binding enzyme 56 282 2.1E-14 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HL41_03720 ad26e0d079e22573053111fe81337334 424 Pfam PF14535 AMP-binding enzyme C-terminal domain 332 422 4.7E-21 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal HL41_03720 ad26e0d079e22573053111fe81337334 424 Gene3D G3DSA:3.30.300.30 324 424 2.7E-26 T 14-10-2018 HL41_03720 ad26e0d079e22573053111fe81337334 424 Gene3D G3DSA:3.40.50.12780 1 323 7.3E-113 T 14-10-2018 HL41_03720 ad26e0d079e22573053111fe81337334 424 PIRSF PIRSF006444 1 424 1.1E-149 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 HL41_02840 166a8327de876ca1082a88583ab8e0d0 311 SUPERFAMILY SSF53328 5 209 4.06E-64 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HL41_02840 166a8327de876ca1082a88583ab8e0d0 311 SUPERFAMILY SSF50486 207 310 1.84E-27 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 HL41_02840 166a8327de876ca1082a88583ab8e0d0 311 Gene3D G3DSA:3.40.50.170 1 208 9.9E-77 T 14-10-2018 HL41_02840 166a8327de876ca1082a88583ab8e0d0 311 Pfam PF00551 Formyl transferase 5 183 6.5E-44 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HL41_02840 166a8327de876ca1082a88583ab8e0d0 311 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 4 305 35.026 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 HL41_02840 166a8327de876ca1082a88583ab8e0d0 311 Pfam PF02911 Formyl transferase, C-terminal domain 207 302 9.9E-26 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HL41_02840 166a8327de876ca1082a88583ab8e0d0 311 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 135 158 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HL41_02840 166a8327de876ca1082a88583ab8e0d0 311 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 303 3.3E-88 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 HL41_02840 166a8327de876ca1082a88583ab8e0d0 311 Gene3D G3DSA:3.10.25.10 209 310 6.9E-28 T 14-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HL41_00960 531ac94c0f6f47e5fcf6af199132407d 253 Pfam PF00460 Flagella basal body rod protein 15 42 2.4E-8 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HL41_00960 531ac94c0f6f47e5fcf6af199132407d 253 SUPERFAMILY SSF117143 84 213 1.57E-21 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like HL41_00960 531ac94c0f6f47e5fcf6af199132407d 253 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 18 38 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site HL41_00960 531ac94c0f6f47e5fcf6af199132407d 253 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 14 127 7.4E-37 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G HL41_00960 531ac94c0f6f47e5fcf6af199132407d 253 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 181 251 4.3E-16 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HL41_00960 531ac94c0f6f47e5fcf6af199132407d 253 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 15 232 2.4E-55 T 14-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 Gene3D G3DSA:3.40.50.10490 10 214 2.3E-94 T 14-10-2018 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 225 3.9E-108 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 Gene3D G3DSA:1.10.287.610 97 152 2.3E-94 T 14-10-2018 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 SUPERFAMILY SSF52313 6 231 1.09E-98 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily HL41_01335 7b21637bc8427254077af4cdb20199a2 280 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.9E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.9E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.9E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.9E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.9E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.9E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 43.511 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01335 7b21637bc8427254077af4cdb20199a2 280 Pfam PF00318 Ribosomal protein S2 9 224 2.7E-100 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_06140 5b4e5dd6f9de763b5469226f2fe126cf 117 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 117 17.943 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 HL41_06140 5b4e5dd6f9de763b5469226f2fe126cf 117 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 20 116 8.7E-34 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06140 5b4e5dd6f9de763b5469226f2fe126cf 117 Gene3D G3DSA:1.20.58.1610 1 117 1.4E-38 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_00405 e5b38814bd4f7c7604fc4842a7ca59b1 319 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_00405 e5b38814bd4f7c7604fc4842a7ca59b1 319 Pfam PF13353 4Fe-4S single cluster domain 18 121 2.4E-10 T 14-10-2018 HL41_00405 e5b38814bd4f7c7604fc4842a7ca59b1 319 SUPERFAMILY SSF102114 2 275 1.18E-79 T 14-10-2018 HL41_00405 e5b38814bd4f7c7604fc4842a7ca59b1 319 Pfam PF04055 Radical SAM superfamily 15 176 3.1E-36 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_00405 e5b38814bd4f7c7604fc4842a7ca59b1 319 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 2 319 39.784 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_00405 e5b38814bd4f7c7604fc4842a7ca59b1 319 SMART SM00729 11 215 1.9E-19 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_00405 e5b38814bd4f7c7604fc4842a7ca59b1 319 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 2 319 2.1E-112 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_00405 e5b38814bd4f7c7604fc4842a7ca59b1 319 Pfam PF06463 Molybdenum Cofactor Synthesis C 182 306 1.9E-35 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_00405 e5b38814bd4f7c7604fc4842a7ca59b1 319 Gene3D G3DSA:3.20.20.70 1 319 1.2E-100 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 Gene3D G3DSA:3.40.50.300 182 368 1.2E-70 T 14-10-2018 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 Pfam PF13185 GAF domain 34 168 1.7E-12 T 14-10-2018 IPR003018 GAF domain GO:0005515 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 409 418 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 Pfam PF02954 Bacterial regulatory protein, Fis family 467 507 1.6E-14 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 Pfam PF00158 Sigma-54 interaction domain 198 363 1.7E-72 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 Gene3D G3DSA:1.10.8.60 369 440 3.9E-27 T 14-10-2018 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 Gene3D G3DSA:3.30.450.40 8 180 2.0E-51 T 14-10-2018 IPR029016 GAF-like domain superfamily HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 283 298 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 SUPERFAMILY SSF52540 197 440 2.18E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 221 234 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 Gene3D G3DSA:1.10.10.60 441 510 5.0E-18 T 14-10-2018 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 SMART SM00382 217 360 2.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 SUPERFAMILY SSF55781 6 168 2.16E-26 T 14-10-2018 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 473 490 6.0E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 490 510 6.0E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 SUPERFAMILY SSF46689 409 509 8.96E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_02135 d75d49d9f6457fb991b5d89baa2d3649 510 SMART SM00065 29 178 7.7E-18 T 14-10-2018 IPR003018 GAF domain GO:0005515 HL41_04270 d90bf46db1a01e902758b956dcdcdc84 69 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_04270 d90bf46db1a01e902758b956dcdcdc84 69 SUPERFAMILY SSF54862 5 61 6.42E-13 T 14-10-2018 HL41_04270 d90bf46db1a01e902758b956dcdcdc84 69 Gene3D G3DSA:3.30.70.20 4 62 6.0E-17 T 14-10-2018 HL41_04270 d90bf46db1a01e902758b956dcdcdc84 69 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 61 1.7E-10 T 14-10-2018 HL41_04270 d90bf46db1a01e902758b956dcdcdc84 69 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.9E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 HL41_04270 d90bf46db1a01e902758b956dcdcdc84 69 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.9E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 HL41_04270 d90bf46db1a01e902758b956dcdcdc84 69 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 2.9E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 HL41_05855 64c66d6728ac9845cf16f990c3ba92de 159 SUPERFAMILY SSF50475 9 154 6.38E-47 T 14-10-2018 HL41_05855 64c66d6728ac9845cf16f990c3ba92de 159 SMART SM00903 11 155 2.2E-39 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 HL41_05855 64c66d6728ac9845cf16f990c3ba92de 159 Pfam PF01613 Flavin reductase like domain 11 153 1.8E-33 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 HL41_05855 64c66d6728ac9845cf16f990c3ba92de 159 Gene3D G3DSA:2.30.110.10 2 154 3.5E-45 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 Gene3D G3DSA:3.40.50.720 2 247 5.1E-93 T 14-10-2018 HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 6 245 4.6E-96 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 SUPERFAMILY SSF51735 4 246 7.63E-95 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 245 3.9E-107 T 14-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 8.8E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.8E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.8E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 1.1E-73 T 14-10-2018 HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 191 1.9E-5 T 14-10-2018 HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HL41_05755 e3677ce8df4d7f0d0f8a5adb4972aa88 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HL41_04745 82e8325866fee44b998a96593c08dcaf 217 Gene3D G3DSA:2.40.30.20 101 205 2.3E-35 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_04745 82e8325866fee44b998a96593c08dcaf 217 SUPERFAMILY SSF63380 1 92 3.32E-25 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel HL41_04745 82e8325866fee44b998a96593c08dcaf 217 Gene3D G3DSA:2.40.30.20 1 88 4.5E-26 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_04745 82e8325866fee44b998a96593c08dcaf 217 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 203 2.6E-68 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_04745 82e8325866fee44b998a96593c08dcaf 217 SUPERFAMILY SSF63380 92 198 9.35E-35 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel HL41_04745 82e8325866fee44b998a96593c08dcaf 217 Pfam PF00677 Lumazine binding domain 99 183 2.9E-25 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_04745 82e8325866fee44b998a96593c08dcaf 217 Pfam PF00677 Lumazine binding domain 3 86 1.1E-20 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_04745 82e8325866fee44b998a96593c08dcaf 217 PIRSF PIRSF000498 1 211 3.1E-74 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_04835 851edd7dc2ad280cabe74589e0fe2863 149 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 2 142 3.0E-32 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HL41_04835 851edd7dc2ad280cabe74589e0fe2863 149 Pfam PF02381 MraZ protein, putative antitoxin-like 1 63 7.7E-12 T 14-10-2018 IPR020603 MraZ domain HL41_04835 851edd7dc2ad280cabe74589e0fe2863 149 Pfam PF02381 MraZ protein, putative antitoxin-like 76 137 2.1E-15 T 14-10-2018 IPR020603 MraZ domain HL41_04835 851edd7dc2ad280cabe74589e0fe2863 149 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 149 45.233 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HL41_04835 851edd7dc2ad280cabe74589e0fe2863 149 SUPERFAMILY SSF89447 1 139 1.15E-43 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily HL41_04835 851edd7dc2ad280cabe74589e0fe2863 149 Gene3D G3DSA:2.40.330.20 1 144 3.2E-44 T 14-10-2018 IPR038619 MraZ superfamily HL41_04835 851edd7dc2ad280cabe74589e0fe2863 149 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 140 4.2E-38 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HL41_07415 34c544caee7744bf947bd7ca2f2f69e0 353 Pfam PF04055 Radical SAM superfamily 58 228 2.2E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_07415 34c544caee7744bf947bd7ca2f2f69e0 353 SUPERFAMILY SSF102114 14 343 1.06E-52 T 14-10-2018 HL41_07415 34c544caee7744bf947bd7ca2f2f69e0 353 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 13 353 52.363 T 14-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 HL41_07415 34c544caee7744bf947bd7ca2f2f69e0 353 Gene3D G3DSA:3.20.20.70 2 348 5.4E-60 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_07415 34c544caee7744bf947bd7ca2f2f69e0 353 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 15 351 1.8E-160 T 14-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 HL41_07415 34c544caee7744bf947bd7ca2f2f69e0 353 SMART SM00729 53 270 0.0018 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_07415 34c544caee7744bf947bd7ca2f2f69e0 353 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 49 350 5.1E-123 T 14-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 HL41_07415 34c544caee7744bf947bd7ca2f2f69e0 353 PIRSF PIRSF004762 2 352 4.9E-116 T 14-10-2018 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 SUPERFAMILY SSF50249 2 145 3.43E-42 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 SUPERFAMILY SSF55681 152 492 1.99E-118 T 14-10-2018 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 Pfam PF01336 OB-fold nucleic acid binding domain 59 136 9.4E-17 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 10 494 44.151 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 Gene3D G3DSA:3.30.930.10 148 497 5.8E-133 T 14-10-2018 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 494 1.1E-200 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 376 392 8.9E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 205 221 8.9E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 234 247 8.9E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 252 269 8.9E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 189 199 8.9E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 Gene3D G3DSA:2.40.50.140 1 147 4.4E-47 T 14-10-2018 HL41_00935 75f7a4d2754a2582ffaf644d5e011421 497 Pfam PF00152 tRNA synthetases class II (D, K and N) 153 491 1.4E-79 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_02945 cfc78c688b4324ed5f124c98b077101d 145 Pfam PF00075 RNase H 3 138 1.6E-41 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 HL41_02945 cfc78c688b4324ed5f124c98b077101d 145 SUPERFAMILY SSF53098 1 140 5.18E-51 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily HL41_02945 cfc78c688b4324ed5f124c98b077101d 145 Gene3D G3DSA:3.30.420.10 1 144 3.3E-56 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HL41_02945 cfc78c688b4324ed5f124c98b077101d 145 Hamap MF_00042 Ribonuclease H [rnhA]. 1 145 29.089 T 14-10-2018 IPR022892 Ribonuclease HI GO:0004523 HL41_08920 7128e7b075045af785a2752a5d8cb050 666 SUPERFAMILY SSF56425 274 419 2.82E-68 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_08920 7128e7b075045af785a2752a5d8cb050 666 Gene3D G3DSA:3.90.700.10 299 429 8.9E-283 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_08920 7128e7b075045af785a2752a5d8cb050 666 TIGRFAM TIGR02061 aprA: adenylylsulfate reductase, alpha subunit 24 660 4.9E-295 T 14-10-2018 IPR011803 Adenylylsulphate reductase, alpha subunit KEGG: 00920+1.8.99.2|MetaCyc: PWY-5278|MetaCyc: PWY-5279 HL41_08920 7128e7b075045af785a2752a5d8cb050 666 Pfam PF02910 Fumarate reductase flavoprotein C-term 544 655 1.0E-5 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_08920 7128e7b075045af785a2752a5d8cb050 666 PIRSF PIRSF000171 13 663 2.8E-242 T 14-10-2018 HL41_08920 7128e7b075045af785a2752a5d8cb050 666 SUPERFAMILY SSF46977 528 660 2.62E-40 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_08920 7128e7b075045af785a2752a5d8cb050 666 Gene3D G3DSA:3.50.50.90 22 659 8.9E-283 T 14-10-2018 HL41_08920 7128e7b075045af785a2752a5d8cb050 666 Pfam PF00890 FAD binding domain 24 275 1.8E-12 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_08920 7128e7b075045af785a2752a5d8cb050 666 SUPERFAMILY SSF51905 14 513 2.89E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_00330 8b63bb600ba4ec26aaf15bc0077b5e76 78 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 14-10-2018 IPR019844 Cold-shock conserved site HL41_00330 8b63bb600ba4ec26aaf15bc0077b5e76 78 SMART SM00357 3 66 3.5E-28 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 HL41_00330 8b63bb600ba4ec26aaf15bc0077b5e76 78 PRINTS PR00050 Cold shock protein signature 39 57 7.4E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HL41_00330 8b63bb600ba4ec26aaf15bc0077b5e76 78 PRINTS PR00050 Cold shock protein signature 4 19 7.4E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HL41_00330 8b63bb600ba4ec26aaf15bc0077b5e76 78 PRINTS PR00050 Cold shock protein signature 24 33 7.4E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HL41_00330 8b63bb600ba4ec26aaf15bc0077b5e76 78 PIRSF PIRSF002599 1 74 4.3E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 HL41_00330 8b63bb600ba4ec26aaf15bc0077b5e76 78 SUPERFAMILY SSF50249 1 66 2.52E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_00330 8b63bb600ba4ec26aaf15bc0077b5e76 78 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 5.8E-29 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HL41_00330 8b63bb600ba4ec26aaf15bc0077b5e76 78 Gene3D G3DSA:2.40.50.140 2 67 1.1E-28 T 14-10-2018 HL41_07925 38537402bdab83e523b1e2a1e3b25bfd 447 Gene3D G3DSA:3.80.30.20 150 385 1.6E-75 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HL41_07925 38537402bdab83e523b1e2a1e3b25bfd 447 SMART SM00729 152 374 3.3E-46 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_07925 38537402bdab83e523b1e2a1e3b25bfd 447 Gene3D G3DSA:3.40.50.12160 2 105 1.6E-18 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily HL41_07925 38537402bdab83e523b1e2a1e3b25bfd 447 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 156 176 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 HL41_07925 38537402bdab83e523b1e2a1e3b25bfd 447 Pfam PF00919 Uncharacterized protein family UPF0004 3 87 7.5E-22 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 HL41_07925 38537402bdab83e523b1e2a1e3b25bfd 447 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 417 1.2E-118 T 14-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 HL41_07925 38537402bdab83e523b1e2a1e3b25bfd 447 SUPERFAMILY SSF102114 133 378 3.27E-48 T 14-10-2018 HL41_07925 38537402bdab83e523b1e2a1e3b25bfd 447 Pfam PF04055 Radical SAM superfamily 157 330 5.9E-19 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_07925 38537402bdab83e523b1e2a1e3b25bfd 447 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 443 2.1E-107 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 17 175 7.4E-41 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 15 338 2.0E-119 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 SUPERFAMILY SSF52490 17 209 5.49E-66 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 13 362 36.537 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 Gene3D G3DSA:3.40.50.1440 8 224 1.6E-77 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 Pfam PF12327 FtsZ family, C-terminal domain 227 323 4.2E-27 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 SMART SM00864 17 209 9.9E-105 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 Gene3D G3DSA:3.30.1330.20 230 348 2.2E-32 T 14-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 SMART SM00865 211 331 1.5E-44 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 PRINTS PR00423 Cell division protein FtsZ signature 102 122 2.2E-40 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 PRINTS PR00423 Cell division protein FtsZ signature 193 215 2.2E-40 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 PRINTS PR00423 Cell division protein FtsZ signature 130 151 2.2E-40 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 PRINTS PR00423 Cell division protein FtsZ signature 217 238 2.2E-40 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 SUPERFAMILY SSF55307 208 325 2.75E-35 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 HL41_04770 186b1a6747d19455ff1bb68b5875bdcd 375 ProSitePatterns PS01135 FtsZ protein signature 2. 101 122 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 HL41_03855 eb492c6dc624be5346005ee770ac5dc1 299 SUPERFAMILY SSF161111 9 207 1.57E-53 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily HL41_03855 eb492c6dc624be5346005ee770ac5dc1 299 Pfam PF16916 Dimerisation domain of Zinc Transporter 211 293 9.4E-21 T 14-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain HL41_03855 eb492c6dc624be5346005ee770ac5dc1 299 SUPERFAMILY SSF160240 210 294 6.28E-18 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 HL41_03855 eb492c6dc624be5346005ee770ac5dc1 299 Gene3D G3DSA:1.20.1510.10 9 205 4.0E-54 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily HL41_03855 eb492c6dc624be5346005ee770ac5dc1 299 Pfam PF01545 Cation efflux family 13 206 1.6E-46 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HL41_03855 eb492c6dc624be5346005ee770ac5dc1 299 Gene3D G3DSA:3.30.70.1350 206 299 9.2E-28 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 HL41_03855 eb492c6dc624be5346005ee770ac5dc1 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 10 295 1.7E-72 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HL41_08820 10cb0e0ea83d7663f83e51a366b759b3 389 Gene3D G3DSA:1.20.1250.20 6 204 7.3E-14 T 14-10-2018 HL41_08820 10cb0e0ea83d7663f83e51a366b759b3 389 SUPERFAMILY SSF103473 11 384 4.71E-38 T 14-10-2018 IPR036259 MFS transporter superfamily HL41_08820 10cb0e0ea83d7663f83e51a366b759b3 389 Gene3D G3DSA:1.20.1250.20 210 388 1.5E-15 T 14-10-2018 HL41_08820 10cb0e0ea83d7663f83e51a366b759b3 389 Pfam PF07690 Major Facilitator Superfamily 38 349 3.2E-22 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Pfam PF00679 Elongation factor G C-terminus 407 494 2.5E-19 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 PRINTS PR00315 GTP-binding elongation factor signature 15 28 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 PRINTS PR00315 GTP-binding elongation factor signature 135 144 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 PRINTS PR00315 GTP-binding elongation factor signature 99 110 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 PRINTS PR00315 GTP-binding elongation factor signature 83 93 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 TIGRFAM TIGR01393 lepA: elongation factor 4 12 603 2.0E-297 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Gene3D G3DSA:2.40.30.10 196 292 1.5E-36 T 14-10-2018 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 SUPERFAMILY SSF54980 300 378 2.63E-19 T 14-10-2018 IPR035647 EF-G domain III/V-like HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Gene3D G3DSA:3.30.70.870 294 375 1.7E-36 T 14-10-2018 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Hamap MF_00071 Elongation factor 4 [lepA]. 1 603 290.171 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Pfam PF06421 GTP-binding protein LepA C-terminus 496 602 4.3E-51 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Pfam PF03144 Elongation factor Tu domain 2 214 284 1.2E-7 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Gene3D G3DSA:3.40.50.300 9 194 2.6E-76 T 14-10-2018 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Gene3D G3DSA:3.30.70.2570 488 562 7.9E-36 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 SUPERFAMILY SSF50447 197 288 4.8E-20 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 SUPERFAMILY SSF54980 407 502 2.59E-21 T 14-10-2018 IPR035647 EF-G domain III/V-like HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 185 5.9E-22 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Pfam PF00009 Elongation factor Tu GTP binding domain 12 191 2.7E-56 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 SUPERFAMILY SSF52540 5 215 9.44E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03040 5ffb9a59e72825c9d9701a95fa4062a2 603 Gene3D G3DSA:3.30.70.3380 376 487 3.4E-39 T 14-10-2018 HL41_08365 536fb94968a221228f6a4353aeac1300 270 Pfam PF03692 Putative zinc- or iron-chelating domain 29 126 7.1E-10 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 6 58 2.4E-15 T 14-10-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 303 310 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 SMART SM00830 10 89 2.9E-25 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 Gene3D G3DSA:3.40.190.10 93 263 1.2E-60 T 14-10-2018 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 Pfam PF01842 ACT domain 276 337 1.3E-10 T 14-10-2018 IPR002912 ACT domain HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 Pfam PF01817 Chorismate mutase type II 10 87 2.8E-20 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 Gene3D G3DSA:3.30.70.260 269 356 4.0E-33 T 14-10-2018 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 SUPERFAMILY SSF48600 5 93 2.44E-20 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 SUPERFAMILY SSF53850 90 273 4.67E-61 T 14-10-2018 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 Gene3D G3DSA:1.20.59.10 2 90 7.1E-27 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 SUPERFAMILY SSF55021 260 355 1.59E-32 T 14-10-2018 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 Pfam PF00800 Prephenate dehydratase 91 267 5.3E-63 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 PIRSF PIRSF001500 1 357 9.7E-128 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 241 263 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HL41_02040 3ad99421e88b6947ca74ee65baca0034 358 Gene3D G3DSA:3.40.190.10 171 254 1.2E-60 T 14-10-2018 HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 SUPERFAMILY SSF50129 1 95 1.6E-37 T 14-10-2018 IPR011032 GroES-like superfamily HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 27.994 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 Gene3D G3DSA:2.30.33.40 1 96 4.2E-40 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 PRINTS PR00297 10kDa chaperonin signature 81 94 5.8E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 PRINTS PR00297 10kDa chaperonin signature 3 18 5.8E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 PRINTS PR00297 10kDa chaperonin signature 25 46 5.8E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 PRINTS PR00297 10kDa chaperonin signature 60 72 5.8E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 SMART SM00883 2 94 2.8E-59 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 4.2E-38 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HL41_04630 48e1a6069ac0ba2696d39cc180505101 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 HL41_01655 13dabcd7ace7abeae94a7fd02e583f79 62 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_01655 13dabcd7ace7abeae94a7fd02e583f79 62 Pfam PF13187 4Fe-4S dicluster domain 11 56 1.9E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_01655 13dabcd7ace7abeae94a7fd02e583f79 62 Gene3D G3DSA:3.30.70.20 2 60 3.5E-14 T 14-10-2018 HL41_01655 13dabcd7ace7abeae94a7fd02e583f79 62 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 42 53 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_01655 13dabcd7ace7abeae94a7fd02e583f79 62 SUPERFAMILY SSF54862 3 59 4.99E-17 T 14-10-2018 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 SUPERFAMILY SSF53738 3 186 3.92E-44 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 450 45.153 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 Gene3D G3DSA:3.40.120.10 262 345 5.8E-73 T 14-10-2018 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 Gene3D G3DSA:3.40.120.10 179 368 5.8E-73 T 14-10-2018 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 Gene3D G3DSA:3.40.120.10 4 154 8.8E-46 T 14-10-2018 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 2.9E-11 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 2.9E-11 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 2.9E-11 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 383 444 1.2E-13 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 162 259 2.7E-18 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 140 4.2E-41 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 373 1.1E-32 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 SUPERFAMILY SSF53738 263 370 6.67E-31 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 SUPERFAMILY SSF53738 161 261 3.61E-29 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 Gene3D G3DSA:3.30.310.50 376 452 8.2E-22 T 14-10-2018 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 SUPERFAMILY SSF55957 363 451 1.57E-21 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_02735 2c0546cc96ddeb200c6d7bb47aab5235 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 444 2.0E-178 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_07560 83c795cff812dced2d81ac51948de64b 808 SUPERFAMILY SSF56784 494 801 3.62E-57 T 14-10-2018 IPR036412 HAD-like superfamily HL41_07560 83c795cff812dced2d81ac51948de64b 808 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 208 804 3.1E-182 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 Pfam PF00702 haloacid dehalogenase-like hydrolase 492 707 1.2E-42 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 497 503 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HL41_07560 83c795cff812dced2d81ac51948de64b 808 Gene3D G3DSA:3.30.70.100 3 72 1.8E-15 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 267 771 2.8E-98 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HL41_07560 83c795cff812dced2d81ac51948de64b 808 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 226 803 8.1E-195 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HL41_07560 83c795cff812dced2d81ac51948de64b 808 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HL41_07560 83c795cff812dced2d81ac51948de64b 808 Gene3D G3DSA:3.30.70.100 73 140 2.0E-7 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 SUPERFAMILY SSF81665 242 495 1.31E-18 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 HL41_07560 83c795cff812dced2d81ac51948de64b 808 Gene3D G3DSA:2.70.150.20 282 399 1.1E-41 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 SUPERFAMILY SSF55008 72 138 2.75E-8 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 HL41_07560 83c795cff812dced2d81ac51948de64b 808 Gene3D G3DSA:3.40.1110.10 506 626 2.1E-85 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HL41_07560 83c795cff812dced2d81ac51948de64b 808 SUPERFAMILY SSF81653 298 395 3.79E-27 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 HL41_07560 83c795cff812dced2d81ac51948de64b 808 SUPERFAMILY SSF55008 6 70 2.88E-14 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 HL41_07560 83c795cff812dced2d81ac51948de64b 808 Pfam PF00403 Heavy-metal-associated domain 9 69 2.8E-15 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HL41_07560 83c795cff812dced2d81ac51948de64b 808 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 345 359 4.0E-25 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 717 729 4.0E-25 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 495 509 4.0E-25 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 641 651 4.0E-25 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 694 713 4.0E-25 T 14-10-2018 HL41_07560 83c795cff812dced2d81ac51948de64b 808 Gene3D G3DSA:3.40.50.1000 477 744 2.1E-85 T 14-10-2018 IPR023214 HAD superfamily HL41_07560 83c795cff812dced2d81ac51948de64b 808 Pfam PF00122 E1-E2 ATPase 295 474 1.3E-58 T 14-10-2018 HL41_03250 f1cc6422bcae13c1ef8acdfb1aac3203 113 SUPERFAMILY SSF51182 8 112 3.43E-18 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily HL41_03250 f1cc6422bcae13c1ef8acdfb1aac3203 113 Pfam PF07883 Cupin domain 43 107 5.5E-14 T 14-10-2018 IPR013096 Cupin 2, conserved barrel HL41_03250 f1cc6422bcae13c1ef8acdfb1aac3203 113 Gene3D G3DSA:2.60.120.10 25 112 2.5E-18 T 14-10-2018 IPR014710 RmlC-like jelly roll fold HL41_03250 f1cc6422bcae13c1ef8acdfb1aac3203 113 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 36 112 0.002 T 14-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 Gene3D G3DSA:1.20.272.10 232 334 4.2E-46 T 14-10-2018 HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 Gene3D G3DSA:3.40.50.300 3 155 1.5E-41 T 14-10-2018 HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 Gene3D G3DSA:1.10.8.60 157 229 4.4E-9 T 14-10-2018 HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 SUPERFAMILY SSF48019 242 424 4.36E-75 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 Pfam PF12002 MgsA AAA+ ATPase C terminal 257 421 1.8E-69 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 SMART SM00382 41 157 2.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 Gene3D G3DSA:1.10.3710.10 335 428 2.8E-31 T 14-10-2018 HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 SUPERFAMILY SSF52540 5 225 1.85E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 154 3.8E-17 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HL41_05475 571a555a2d7ff922a13230e9c2ffa3a8 431 Pfam PF16193 AAA C-terminal domain 179 256 1.0E-23 T 14-10-2018 IPR032423 AAA C-terminal domain HL41_00485 3438e5731f1a55f5f2473fc917a6c556 347 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 8 347 42.018 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HL41_00485 3438e5731f1a55f5f2473fc917a6c556 347 Pfam PF02547 Queuosine biosynthesis protein 11 346 7.7E-119 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HL41_00485 3438e5731f1a55f5f2473fc917a6c556 347 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 8 347 3.3E-115 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HL41_00485 3438e5731f1a55f5f2473fc917a6c556 347 SUPERFAMILY SSF111337 9 347 8.37E-116 T 14-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HL41_00485 3438e5731f1a55f5f2473fc917a6c556 347 Gene3D G3DSA:2.40.10.240 77 164 1.0E-16 T 14-10-2018 HL41_00485 3438e5731f1a55f5f2473fc917a6c556 347 Gene3D G3DSA:3.40.1780.10 1 76 7.6E-18 T 14-10-2018 HL41_00485 3438e5731f1a55f5f2473fc917a6c556 347 Gene3D G3DSA:3.40.1780.10 165 347 5.7E-71 T 14-10-2018 HL41_01450 32fac4bed182b679e2ccf16731e7c58d 127 Gene3D G3DSA:3.40.1350.10 17 127 2.4E-27 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 HL41_01450 32fac4bed182b679e2ccf16731e7c58d 127 Hamap MF_00048 UPF0102 protein YraN [yraN]. 11 124 19.456 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 HL41_01450 32fac4bed182b679e2ccf16731e7c58d 127 Pfam PF02021 Uncharacterised protein family UPF0102 18 111 3.7E-21 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 HL41_01450 32fac4bed182b679e2ccf16731e7c58d 127 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 12 116 4.5E-21 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 HL41_01450 32fac4bed182b679e2ccf16731e7c58d 127 SUPERFAMILY SSF52980 17 116 2.77E-19 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 Gene3D G3DSA:3.30.1550.10 2 71 4.7E-33 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 Gene3D G3DSA:1.10.10.2720 72 141 1.3E-29 T 14-10-2018 HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 3.2E-64 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 5.3E-29 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.394 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 SUPERFAMILY SSF54747 3 72 1.07E-29 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 3.4E-25 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 SMART SM00649 9 140 4.6E-84 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 2.0E-11 T 14-10-2018 HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_08980 10bd7ddb3dde9a3d488936e95179f4e8 141 SUPERFAMILY SSF46906 67 139 1.7E-26 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily HL41_06820 71dbcf4c8017f33ef13f1599ab69d969 237 Gene3D G3DSA:3.10.580.10 1 138 1.4E-40 T 14-10-2018 HL41_06820 71dbcf4c8017f33ef13f1599ab69d969 237 SMART SM00116 10 57 9.2E-12 T 14-10-2018 IPR000644 CBS domain HL41_06820 71dbcf4c8017f33ef13f1599ab69d969 237 SMART SM00116 84 132 1.1E-12 T 14-10-2018 IPR000644 CBS domain HL41_06820 71dbcf4c8017f33ef13f1599ab69d969 237 Pfam PF00571 CBS domain 77 130 6.2E-17 T 14-10-2018 IPR000644 CBS domain HL41_06820 71dbcf4c8017f33ef13f1599ab69d969 237 Pfam PF00571 CBS domain 3 54 1.1E-11 T 14-10-2018 IPR000644 CBS domain HL41_06820 71dbcf4c8017f33ef13f1599ab69d969 237 SUPERFAMILY SSF54631 1 133 8.45E-37 T 14-10-2018 HL41_04665 c04cf845b9a04be054437676def2965d 243 SUPERFAMILY SSF102215 1 234 1.57E-53 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 HL41_04665 c04cf845b9a04be054437676def2965d 243 Pfam PF02633 Creatinine amidohydrolase 4 228 3.0E-50 T 14-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 HL41_04665 c04cf845b9a04be054437676def2965d 243 Gene3D G3DSA:3.40.50.10310 1 236 6.8E-59 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 HL41_03975 e73fa82baa902182e81323efda7d3e4c 444 Pfam PF00120 Glutamine synthetase, catalytic domain 109 440 1.6E-125 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HL41_03975 e73fa82baa902182e81323efda7d3e4c 444 SUPERFAMILY SSF54368 10 107 2.22E-34 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HL41_03975 e73fa82baa902182e81323efda7d3e4c 444 SMART SM01230 108 354 4.6E-128 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HL41_03975 e73fa82baa902182e81323efda7d3e4c 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 20 102 9.9E-32 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 HL41_03975 e73fa82baa902182e81323efda7d3e4c 444 Gene3D G3DSA:3.30.590.10 111 442 8.2E-121 T 14-10-2018 HL41_03975 e73fa82baa902182e81323efda7d3e4c 444 Gene3D G3DSA:3.10.20.70 7 110 1.1E-41 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HL41_03975 e73fa82baa902182e81323efda7d3e4c 444 SUPERFAMILY SSF55931 109 442 6.28E-120 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 HL41_03335 8d3ba7f6f4ef0f7429a6191f71bfbb1a 421 Gene3D G3DSA:3.10.580.10 179 328 3.2E-39 T 14-10-2018 HL41_03335 8d3ba7f6f4ef0f7429a6191f71bfbb1a 421 SMART SM01091 336 417 3.9E-18 T 14-10-2018 IPR005170 Transporter-associated domain HL41_03335 8d3ba7f6f4ef0f7429a6191f71bfbb1a 421 Pfam PF00571 CBS domain 272 321 6.4E-8 T 14-10-2018 IPR000644 CBS domain HL41_03335 8d3ba7f6f4ef0f7429a6191f71bfbb1a 421 Pfam PF01595 Domain of unknown function DUF21 8 155 1.7E-23 T 14-10-2018 IPR002550 CNNM, transmembrane domain HL41_03335 8d3ba7f6f4ef0f7429a6191f71bfbb1a 421 SUPERFAMILY SSF54631 197 339 2.2E-24 T 14-10-2018 HL41_03335 8d3ba7f6f4ef0f7429a6191f71bfbb1a 421 Gene3D G3DSA:3.30.465.10 329 415 8.9E-18 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 HL41_03335 8d3ba7f6f4ef0f7429a6191f71bfbb1a 421 SUPERFAMILY SSF56176 334 417 1.01E-16 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HL41_03335 8d3ba7f6f4ef0f7429a6191f71bfbb1a 421 Pfam PF03471 Transporter associated domain 337 416 8.5E-18 T 14-10-2018 IPR005170 Transporter-associated domain HL41_08190 8fb96832d31a56258f143aeddb54d840 267 Pfam PF01177 Asp/Glu/Hydantoin racemase 2 211 7.0E-34 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HL41_08190 8fb96832d31a56258f143aeddb54d840 267 SUPERFAMILY SSF53681 106 257 4.41E-35 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HL41_08190 8fb96832d31a56258f143aeddb54d840 267 Hamap MF_00258 Glutamate racemase [murI]. 1 253 31.54 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HL41_08190 8fb96832d31a56258f143aeddb54d840 267 Gene3D G3DSA:3.40.50.1860 92 204 1.2E-84 T 14-10-2018 HL41_08190 8fb96832d31a56258f143aeddb54d840 267 SUPERFAMILY SSF53681 2 104 4.9E-30 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HL41_08190 8fb96832d31a56258f143aeddb54d840 267 TIGRFAM TIGR00067 glut_race: glutamate racemase 2 241 1.0E-61 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HL41_08190 8fb96832d31a56258f143aeddb54d840 267 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 177 187 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HL41_08190 8fb96832d31a56258f143aeddb54d840 267 Gene3D G3DSA:3.40.50.1860 2 250 1.2E-84 T 14-10-2018 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 Pfam PF02954 Bacterial regulatory protein, Fis family 398 436 3.1E-14 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 SUPERFAMILY SSF46689 349 439 4.35E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 420 440 6.5E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 403 420 6.5E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 Pfam PF00158 Sigma-54 interaction domain 145 302 8.7E-62 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 SUPERFAMILY SSF52172 4 181 3.7E-35 T 14-10-2018 IPR011006 CheY-like superfamily HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 Gene3D G3DSA:3.40.50.2300 1 129 2.3E-31 T 14-10-2018 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 350 359 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 Gene3D G3DSA:3.40.50.300 140 307 1.0E-60 T 14-10-2018 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 SMART SM00448 5 117 4.3E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 SUPERFAMILY SSF52540 145 376 3.75E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 Pfam PF00072 Response regulator receiver domain 7 117 8.8E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 Gene3D G3DSA:1.10.8.60 308 374 1.9E-20 T 14-10-2018 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 Gene3D G3DSA:1.10.10.60 376 440 1.3E-15 T 14-10-2018 HL41_07260 4a3947cdfaa102a8e8950e8b1cdfca21 441 SMART SM00382 158 300 2.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_00910 07ab9efc50c3a6200ec8df69aee271a6 206 SMART SM00072 5 186 5.8E-62 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HL41_00910 07ab9efc50c3a6200ec8df69aee271a6 206 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 7 183 3.3E-65 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 HL41_00910 07ab9efc50c3a6200ec8df69aee271a6 206 Pfam PF00625 Guanylate kinase 8 177 1.1E-48 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HL41_00910 07ab9efc50c3a6200ec8df69aee271a6 206 ProSitePatterns PS00856 Guanylate kinase-like signature. 38 55 - T 14-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HL41_00910 07ab9efc50c3a6200ec8df69aee271a6 206 Gene3D G3DSA:3.40.50.300 10 182 2.8E-61 T 14-10-2018 HL41_00910 07ab9efc50c3a6200ec8df69aee271a6 206 Gene3D G3DSA:3.30.63.10 35 94 2.8E-61 T 14-10-2018 HL41_00910 07ab9efc50c3a6200ec8df69aee271a6 206 SUPERFAMILY SSF52540 3 193 6.67E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00910 07ab9efc50c3a6200ec8df69aee271a6 206 Hamap MF_00328 Guanylate kinase [gmk]. 4 186 33.814 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 6.9E-69 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 SUPERFAMILY SSF50249 2 123 4.63E-54 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 40.945 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 Gene3D G3DSA:2.40.50.140 1 123 2.3E-65 T 14-10-2018 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.1E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.1E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.1E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.1E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.1E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.1E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 PIRSF PIRSF002133 1 123 1.2E-56 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05470 990eb1ba03d291baeea413ced4cf8148 123 Pfam PF00164 Ribosomal protein S12/S23 12 123 3.9E-43 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 Gene3D G3DSA:3.30.70.580 65 232 2.9E-45 T 14-10-2018 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 SUPERFAMILY SSF55174 3 70 7.26E-17 T 14-10-2018 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 Pfam PF01479 S4 domain 5 46 2.6E-13 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 Gene3D G3DSA:3.30.70.1560 131 215 2.9E-45 T 14-10-2018 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 102 116 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 SUPERFAMILY SSF55120 63 233 6.33E-35 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 SMART SM00363 4 68 9.2E-14 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 Gene3D G3DSA:3.10.290.10 2 60 7.7E-22 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 Pfam PF00849 RNA pseudouridylate synthase 65 197 6.3E-15 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_02995 9edb1137eefd9394e9c0052d0e02059a 257 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 69 228 7.3E-41 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 PIRSF PIRSF006485 1 437 4.0E-146 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 SUPERFAMILY SSF52540 72 344 6.72E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 160 1.9E-32 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 174 339 5.0E-25 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 PRINTS PR00449 Transforming protein P21 ras signature 286 299 1.4E-5 T 14-10-2018 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 PRINTS PR00449 Transforming protein P21 ras signature 326 348 1.4E-5 T 14-10-2018 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 PRINTS PR00449 Transforming protein P21 ras signature 176 197 1.4E-5 T 14-10-2018 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 Hamap MF_00195 GTPase Der [der]. 1 437 34.456 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 SUPERFAMILY SSF52540 4 86 6.07E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 SUPERFAMILY SSF82653 355 425 9.02E-9 T 14-10-2018 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 434 2.0E-148 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 Gene3D G3DSA:3.30.300.20 350 436 4.5E-22 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 Gene3D G3DSA:3.40.50.300 2 161 7.6E-46 T 14-10-2018 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 Gene3D G3DSA:3.40.50.300 171 349 7.0E-49 T 14-10-2018 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 Pfam PF01926 50S ribosome-binding GTPase 3 120 2.2E-27 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 Pfam PF01926 50S ribosome-binding GTPase 177 296 7.8E-26 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_01125 f6ac8f505fe60ce0e8fb028727a657f7 437 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 354 434 4.6E-22 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like HL41_00355 e45c7c9c83640d23ca00e9e0b8dc664b 492 PIRSF PIRSF000243 3 487 5.8E-129 T 14-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 HL41_00355 e45c7c9c83640d23ca00e9e0b8dc664b 492 Gene3D G3DSA:1.20.140.10 338 440 1.7E-125 T 14-10-2018 HL41_00355 e45c7c9c83640d23ca00e9e0b8dc664b 492 Pfam PF02335 Cytochrome c552 44 481 2.8E-138 T 14-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 HL41_00355 e45c7c9c83640d23ca00e9e0b8dc664b 492 SUPERFAMILY SSF48695 37 482 2.87E-140 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_00355 e45c7c9c83640d23ca00e9e0b8dc664b 492 Gene3D G3DSA:1.10.1130.10 50 328 1.7E-125 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 881 3.2E-242 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 SUPERFAMILY SSF57938 1170 1220 5.89E-5 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:1.10.8.280 274 371 1.2E-163 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 SMART SM00382 597 974 0.0053 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 SMART SM00382 1433 1735 0.64 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Pfam PF00005 ABC transporter 588 822 6.3E-10 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:3.30.190.20 1057 1162 3.8E-13 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 SUPERFAMILY SSF52540 926 1373 3.0E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:1.20.1580.10 87 459 1.2E-163 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:3.40.50.300 1417 1731 2.5E-125 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:3.30.190.20 127 231 1.2E-163 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Pfam PF00005 ABC transporter 1424 1660 3.2E-9 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 SUPERFAMILY SSF52540 1420 1711 3.15E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 SUPERFAMILY SSF52540 9 536 2.27E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:3.40.50.300 912 1018 1.8E-20 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 SUPERFAMILY SSF52540 579 875 1.88E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 ProSitePatterns PS00211 ABC transporters family signature. 1291 1305 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 ProSitePatterns PS00211 ABC transporters family signature. 792 806 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:3.40.50.300 5 558 1.2E-163 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:1.20.1580.10 1492 1630 2.5E-125 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:1.20.1580.10 654 792 1.0E-111 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 ProSitePatterns PS00211 ABC transporters family signature. 1630 1644 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:3.40.50.300 1163 1404 3.7E-50 T 14-10-2018 HL41_05035 24dcf0fc8a739836a39689aaee49515a 1742 Gene3D G3DSA:3.40.50.300 582 895 1.0E-111 T 14-10-2018 HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 Gene3D G3DSA:3.30.420.40 127 288 1.1E-119 T 14-10-2018 HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 Gene3D G3DSA:3.30.420.40 3 310 1.1E-119 T 14-10-2018 HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 ProSitePatterns PS01016 Glycoprotease family signature. 95 115 - T 14-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 308 1.8E-126 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 Pfam PF00814 Glycoprotease family 23 301 8.6E-95 T 14-10-2018 IPR000905 Gcp-like domain HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 3 301 2.2E-104 T 14-10-2018 IPR017861 Kae1/TsaD family HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 3 16 3.1E-47 T 14-10-2018 IPR017861 Kae1/TsaD family HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 258 267 3.1E-47 T 14-10-2018 IPR017861 Kae1/TsaD family HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 129 141 3.1E-47 T 14-10-2018 IPR017861 Kae1/TsaD family HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 96 115 3.1E-47 T 14-10-2018 IPR017861 Kae1/TsaD family HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 152 173 3.1E-47 T 14-10-2018 IPR017861 Kae1/TsaD family HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 75 95 3.1E-47 T 14-10-2018 IPR017861 Kae1/TsaD family HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 SUPERFAMILY SSF53067 1 121 4.79E-30 T 14-10-2018 HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 SUPERFAMILY SSF53067 100 302 1.94E-48 T 14-10-2018 HL41_02295 5c3fb6431a9f79dfc96a33de7c8ef955 332 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 326 60.65 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 HL41_05980 5af6208e159e061fdda9126aef2051a1 279 Pfam PF02548 Ketopantoate hydroxymethyltransferase 12 262 5.4E-103 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HL41_05980 5af6208e159e061fdda9126aef2051a1 279 Gene3D G3DSA:3.20.20.60 10 275 4.7E-106 T 14-10-2018 HL41_05980 5af6208e159e061fdda9126aef2051a1 279 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 266 1.0E-91 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HL41_05980 5af6208e159e061fdda9126aef2051a1 279 SUPERFAMILY SSF51621 9 266 5.38E-95 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 HL41_05980 5af6208e159e061fdda9126aef2051a1 279 PIRSF PIRSF000388 6 269 2.1E-103 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HL41_05980 5af6208e159e061fdda9126aef2051a1 279 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 6 266 39.388 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 537 38.574 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 Gene3D G3DSA:3.20.20.70 2 290 1.4E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 SUPERFAMILY SSF110921 437 527 1.96E-15 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 Gene3D G3DSA:3.30.160.270 414 528 2.8E-7 T 14-10-2018 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 SMART SM00917 384 528 2.6E-13 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 Gene3D G3DSA:1.10.238.260 295 411 2.2E-30 T 14-10-2018 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 Pfam PF08502 LeuA allosteric (dimerisation) domain 385 527 3.7E-19 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 207 220 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 SUPERFAMILY SSF51569 2 305 8.61E-91 T 14-10-2018 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 Pfam PF00682 HMGL-like 5 287 3.6E-91 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HL41_05770 7c7adf0d627cc26b1bb5e837e4b069b7 546 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 525 1.3E-182 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_00035 f86138dbb85f24882d13170ceeac7d4b 149 Gene3D G3DSA:3.40.50.1450 4 146 2.2E-29 T 14-10-2018 IPR023430 Peptidase HybD-like domain superfamily HL41_00035 f86138dbb85f24882d13170ceeac7d4b 149 Pfam PF01750 Hydrogenase maturation protease 43 143 8.6E-12 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HL41_00035 f86138dbb85f24882d13170ceeac7d4b 149 SUPERFAMILY SSF53163 4 147 7.19E-26 T 14-10-2018 IPR023430 Peptidase HybD-like domain superfamily HL41_00035 f86138dbb85f24882d13170ceeac7d4b 149 PRINTS PR00446 Hydrogen uptake protein signature 63 79 5.7E-6 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HL41_00035 f86138dbb85f24882d13170ceeac7d4b 149 PRINTS PR00446 Hydrogen uptake protein signature 5 17 5.7E-6 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HL41_00035 f86138dbb85f24882d13170ceeac7d4b 149 PRINTS PR00446 Hydrogen uptake protein signature 17 28 5.7E-6 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HL41_00035 f86138dbb85f24882d13170ceeac7d4b 149 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 7 145 5.1E-26 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HL41_02720 c4f2fa8ce02d082d82ab95bed4bfca23 391 Gene3D G3DSA:2.30.130.10 5 75 1.5E-15 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 HL41_02720 c4f2fa8ce02d082d82ab95bed4bfca23 391 Gene3D G3DSA:3.40.50.150 182 390 4.9E-48 T 14-10-2018 HL41_02720 c4f2fa8ce02d082d82ab95bed4bfca23 391 SUPERFAMILY SSF53335 83 385 1.09E-53 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_02720 c4f2fa8ce02d082d82ab95bed4bfca23 391 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 116 303 1.1E-13 T 14-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 HL41_02720 c4f2fa8ce02d082d82ab95bed4bfca23 391 Gene3D G3DSA:3.30.750.80 76 180 2.1E-31 T 14-10-2018 HL41_02720 c4f2fa8ce02d082d82ab95bed4bfca23 391 SUPERFAMILY SSF88697 4 77 2.49E-10 T 14-10-2018 IPR015947 PUA-like superfamily HL41_05945 a4114530ee644c29b62a3c0aa1a56968 126 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 3 36 4.1E-17 T 14-10-2018 IPR004462 Desulforodoxin domain GO:0005506 HL41_05945 a4114530ee644c29b62a3c0aa1a56968 126 Pfam PF01880 Desulfoferrodoxin 42 124 1.0E-22 T 14-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 HL41_05945 a4114530ee644c29b62a3c0aa1a56968 126 Gene3D G3DSA:2.60.40.730 40 126 2.1E-33 T 14-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 HL41_05945 a4114530ee644c29b62a3c0aa1a56968 126 TIGRFAM TIGR00320 dfx_rbo: desulfoferrodoxin 1 124 1.1E-57 T 14-10-2018 IPR004793 Desulfoferrodoxin GO:0005506|GO:0019430 HL41_05945 a4114530ee644c29b62a3c0aa1a56968 126 Gene3D G3DSA:2.20.28.100 1 38 7.0E-16 T 14-10-2018 IPR038094 Desulforodoxin domain superfamily HL41_05945 a4114530ee644c29b62a3c0aa1a56968 126 SUPERFAMILY SSF57802 4 36 3.06E-11 T 14-10-2018 HL41_05945 a4114530ee644c29b62a3c0aa1a56968 126 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 41 125 4.1E-23 T 14-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 HL41_05945 a4114530ee644c29b62a3c0aa1a56968 126 TIGRFAM TIGR00319 desulf_FeS4: desulfoferrodoxin FeS4 iron-binding domain 1 34 1.1E-15 T 14-10-2018 IPR004462 Desulforodoxin domain GO:0005506 HL41_05945 a4114530ee644c29b62a3c0aa1a56968 126 SUPERFAMILY SSF49367 34 124 4.58E-33 T 14-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 HL41_07905 7495a87182b3e32342780b07335299cd 403 Pfam PF13439 Glycosyltransferase Family 4 54 202 2.3E-10 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 HL41_07905 7495a87182b3e32342780b07335299cd 403 Gene3D G3DSA:3.40.50.2000 200 383 3.7E-78 T 14-10-2018 HL41_07905 7495a87182b3e32342780b07335299cd 403 Gene3D G3DSA:3.40.50.2000 53 396 3.7E-78 T 14-10-2018 HL41_07905 7495a87182b3e32342780b07335299cd 403 SUPERFAMILY SSF53756 8 401 4.93E-83 T 14-10-2018 HL41_07905 7495a87182b3e32342780b07335299cd 403 Pfam PF00534 Glycosyl transferases group 1 212 378 3.1E-46 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 HL41_09025 732393408623fd29b071034a32ef88e6 379 SUPERFAMILY SSF55031 177 275 5.89E-22 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain HL41_09025 732393408623fd29b071034a32ef88e6 379 Gene3D G3DSA:3.30.70.360 175 292 2.2E-115 T 14-10-2018 HL41_09025 732393408623fd29b071034a32ef88e6 379 Gene3D G3DSA:3.40.630.10 14 367 2.2E-115 T 14-10-2018 HL41_09025 732393408623fd29b071034a32ef88e6 379 Pfam PF01546 Peptidase family M20/M25/M40 73 372 2.6E-18 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 HL41_09025 732393408623fd29b071034a32ef88e6 379 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 371 5.7E-93 T 14-10-2018 IPR010162 Peptidase M20B, peptidase T-like HL41_09025 732393408623fd29b071034a32ef88e6 379 PIRSF PIRSF001123 290 378 1.1E-5 T 14-10-2018 IPR008007 Peptidase M42 HL41_09025 732393408623fd29b071034a32ef88e6 379 PIRSF PIRSF001123 5 96 0.0095 T 14-10-2018 IPR008007 Peptidase M42 HL41_09025 732393408623fd29b071034a32ef88e6 379 PIRSF PIRSF001123 86 164 1.3E-4 T 14-10-2018 IPR008007 Peptidase M42 HL41_09025 732393408623fd29b071034a32ef88e6 379 Pfam PF07687 Peptidase dimerisation domain 179 272 6.0E-21 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain HL41_09025 732393408623fd29b071034a32ef88e6 379 SUPERFAMILY SSF53187 5 372 1.72E-56 T 14-10-2018 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 SUPERFAMILY SSF52540 317 578 3.15E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 Hamap MF_01125 Reverse gyrase [rgy]. 1 1163 58.051 T 14-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 TIGRFAM TIGR01054 rgy: reverse gyrase 5 1153 0.0 T 14-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 SMART SM00436 744 830 6.2E-37 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 Gene3D G3DSA:1.10.460.10 774 1151 4.4E-131 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 SUPERFAMILY SSF52540 3 277 1.04E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 717 730 4.0E-30 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 987 1003 4.0E-30 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1077 1091 4.0E-30 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 907 916 4.0E-30 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 803 821 4.0E-30 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 Gene3D G3DSA:2.60.510.20 825 1061 4.4E-131 T 14-10-2018 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 SMART SM00493 599 743 2.6E-19 T 14-10-2018 IPR006171 TOPRIM domain HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 SMART SM00487 79 297 1.4E-21 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 SUPERFAMILY SSF56712 598 1160 9.55E-124 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 Gene3D G3DSA:1.10.290.10 875 998 4.4E-131 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 Pfam PF01751 Toprim domain 601 753 1.3E-17 T 14-10-2018 IPR006171 TOPRIM domain HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 Gene3D G3DSA:3.40.50.140 598 773 1.9E-26 T 14-10-2018 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 SMART SM00382 96 282 0.0022 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 Pfam PF01131 DNA topoisomerase 769 1151 5.3E-78 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 Gene3D G3DSA:3.40.50.300 62 287 1.1E-70 T 14-10-2018 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 SMART SM00437 865 1115 1.4E-72 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 HL41_06810 a0c40555d615d2cbecbe91a3caefe254 1166 Pfam PF00270 DEAD/DEAH box helicase 93 269 2.8E-11 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HL41_00190 5469f998d375b3fc5c3675749d1aa95f 126 Pfam PF07238 PilZ domain 4 88 6.5E-8 T 14-10-2018 IPR009875 PilZ domain GO:0035438 HL41_00190 5469f998d375b3fc5c3675749d1aa95f 126 Gene3D G3DSA:2.40.10.220 2 106 1.0E-6 T 14-10-2018 HL41_00190 5469f998d375b3fc5c3675749d1aa95f 126 SUPERFAMILY SSF141371 1 86 2.94E-7 T 14-10-2018 HL41_06415 3a5501dd136982fde0d48b3aa7b0f863 282 SUPERFAMILY SSF51735 1 276 1.56E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_06415 3a5501dd136982fde0d48b3aa7b0f863 282 Gene3D G3DSA:3.40.50.720 2 266 3.1E-95 T 14-10-2018 HL41_06415 3a5501dd136982fde0d48b3aa7b0f863 282 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 277 5.2E-86 T 14-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 HL41_06415 3a5501dd136982fde0d48b3aa7b0f863 282 Gene3D G3DSA:3.90.25.10 159 272 3.1E-95 T 14-10-2018 HL41_06415 3a5501dd136982fde0d48b3aa7b0f863 282 Pfam PF04321 RmlD substrate binding domain 1 277 1.6E-88 T 14-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 324 330 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 19 846 1.1E-158 T 14-10-2018 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 1.1E-43 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 322 336 1.1E-43 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 515 525 1.1E-43 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 599 618 1.1E-43 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 634 1.1E-43 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 504 1.1E-43 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 Pfam PF00702 haloacid dehalogenase-like hydrolase 321 613 4.1E-24 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 SUPERFAMILY SSF81665 2 856 3.79E-136 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 379 542 1.5E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 569 690 4.1E-37 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 345 1.4E-50 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 Gene3D G3DSA:1.20.1110.10 754 857 1.4E-21 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 SUPERFAMILY SSF81660 329 497 1.11E-44 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 SUPERFAMILY SSF56784 321 702 2.2E-62 T 14-10-2018 IPR036412 HAD-like superfamily HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 70 2.1E-19 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 SMART SM00831 2 75 2.7E-27 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 SUPERFAMILY SSF81653 113 223 1.83E-36 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 Pfam PF00122 E1-E2 ATPase 112 299 1.2E-60 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 Gene3D G3DSA:1.20.1110.10 51 745 1.7E-211 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 454 472 3.1E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 599 615 3.1E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 571 587 3.1E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 630 655 3.1E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 Gene3D G3DSA:3.40.50.1000 319 638 1.7E-211 T 14-10-2018 IPR023214 HAD superfamily HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 Gene3D G3DSA:2.70.150.10 22 225 1.7E-211 T 14-10-2018 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 Pfam PF00689 Cation transporting ATPase, C-terminus 682 851 7.1E-53 T 14-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 HL41_06580 3b5d7181f6e836253a4450ea29caf22b 864 Gene3D G3DSA:3.40.1110.10 332 500 1.7E-211 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HL41_01690 bb7137b97155988be7e97f60930bad54 354 Pfam PF11104 Type IV pilus assembly protein PilM; 26 353 2.8E-18 T 14-10-2018 IPR005883 Type IV pilus assembly protein PilM HL41_01690 bb7137b97155988be7e97f60930bad54 354 SUPERFAMILY SSF53067 24 314 2.2E-6 T 14-10-2018 HL41_01690 bb7137b97155988be7e97f60930bad54 354 Gene3D G3DSA:3.30.1490.300 101 152 7.0E-38 T 14-10-2018 HL41_01690 bb7137b97155988be7e97f60930bad54 354 Gene3D G3DSA:3.30.420.40 190 317 7.0E-38 T 14-10-2018 HL41_01690 bb7137b97155988be7e97f60930bad54 354 Gene3D G3DSA:3.30.420.40 25 351 7.0E-38 T 14-10-2018 HL41_04450 30008392baa52c12cab80c01878ef87f 279 PIRSF PIRSF000477 1 277 6.6E-96 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 HL41_04450 30008392baa52c12cab80c01878ef87f 279 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 29 274 2.2E-89 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 HL41_04450 30008392baa52c12cab80c01878ef87f 279 Gene3D G3DSA:3.40.50.1580 2 278 5.1E-99 T 14-10-2018 HL41_04450 30008392baa52c12cab80c01878ef87f 279 SUPERFAMILY SSF53167 7 277 1.61E-83 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 HL41_04450 30008392baa52c12cab80c01878ef87f 279 Pfam PF01048 Phosphorylase superfamily 28 275 5.2E-48 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HL41_04450 30008392baa52c12cab80c01878ef87f 279 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 28 273 4.3E-93 T 14-10-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 175 2.7E-45 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 SUPERFAMILY SSF47928 5 106 1.16E-17 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 PRINTS PR00125 ATP synthase delta subunit signature 6 25 1.7E-20 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 PRINTS PR00125 ATP synthase delta subunit signature 76 87 1.7E-20 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 PRINTS PR00125 ATP synthase delta subunit signature 137 152 1.7E-20 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 PRINTS PR00125 ATP synthase delta subunit signature 87 101 1.7E-20 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 PRINTS PR00125 ATP synthase delta subunit signature 152 170 1.7E-20 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 179 19.311 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 175 7.9E-35 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 139 158 - T 14-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01080 fc3b133440c8b34adbdcc5ab330dac2a 182 Gene3D G3DSA:1.10.520.20 3 106 4.0E-12 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_07660 94da0422f8f7ce64914ea457d8a4ce52 588 Gene3D G3DSA:3.10.410.10 474 562 3.1E-30 T 14-10-2018 HL41_07660 94da0422f8f7ce64914ea457d8a4ce52 588 Gene3D G3DSA:3.40.50.300 20 469 2.2E-171 T 14-10-2018 HL41_07660 94da0422f8f7ce64914ea457d8a4ce52 588 Pfam PF01268 Formate--tetrahydrofolate ligase 13 587 9.6E-217 T 14-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HL41_07660 94da0422f8f7ce64914ea457d8a4ce52 588 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 114 124 - T 14-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HL41_07660 94da0422f8f7ce64914ea457d8a4ce52 588 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 9 587 38.141 T 14-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HL41_07660 94da0422f8f7ce64914ea457d8a4ce52 588 Gene3D G3DSA:3.30.1510.10 140 271 2.2E-171 T 14-10-2018 HL41_07660 94da0422f8f7ce64914ea457d8a4ce52 588 SUPERFAMILY SSF52540 19 586 5.31E-195 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05685 78b2fd337c45cdbdb49e9e7c8ea572af 85 SUPERFAMILY SSF46785 4 73 1.18E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_05685 78b2fd337c45cdbdb49e9e7c8ea572af 85 Gene3D G3DSA:1.10.10.10 3 82 6.3E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_05685 78b2fd337c45cdbdb49e9e7c8ea572af 85 Pfam PF08679 Dissimilatory sulfite reductase D (DsrD) 6 71 1.4E-28 T 14-10-2018 IPR014793 Dissimilatory sulphite reductase D HL41_03970 462546bc1cc0d17d66d215dd7ec80a04 559 Gene3D G3DSA:3.40.50.620 292 559 8.8E-107 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_03970 462546bc1cc0d17d66d215dd7ec80a04 559 SUPERFAMILY SSF56317 1 250 1.57E-47 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily HL41_03970 462546bc1cc0d17d66d215dd7ec80a04 559 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 4 557 24.305 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 HL41_03970 462546bc1cc0d17d66d215dd7ec80a04 559 Gene3D G3DSA:3.60.110.10 1 268 1.1E-60 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily HL41_03970 462546bc1cc0d17d66d215dd7ec80a04 559 TIGRFAM TIGR00552 nadE: NAD+ synthetase 295 544 2.5E-69 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 HL41_03970 462546bc1cc0d17d66d215dd7ec80a04 559 Pfam PF02540 NAD synthase 295 539 2.2E-87 T 14-10-2018 IPR022310 NAD/GMP synthase HL41_03970 462546bc1cc0d17d66d215dd7ec80a04 559 Pfam PF00795 Carbon-nitrogen hydrolase 6 245 8.6E-22 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 HL41_03970 462546bc1cc0d17d66d215dd7ec80a04 559 PIRSF PIRSF006630 1 559 3.2E-165 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 HL41_03970 462546bc1cc0d17d66d215dd7ec80a04 559 SUPERFAMILY SSF52402 290 547 1.52E-77 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 6 803 89.767 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 SUPERFAMILY SSF56719 396 796 7.06E-84 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HL41_02005 9071255759e548e7d3be0a074df895a3 803 Gene3D G3DSA:3.30.230.10 223 394 3.1E-70 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_02005 9071255759e548e7d3be0a074df895a3 803 SUPERFAMILY SSF55874 9 220 5.24E-73 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_02005 9071255759e548e7d3be0a074df895a3 803 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 177 4.1E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_02005 9071255759e548e7d3be0a074df895a3 803 SMART SM00387 34 178 2.7E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_02005 9071255759e548e7d3be0a074df895a3 803 SMART SM00433 38 796 2.0E-268 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR00418 DNA topoisomerase II family signature 489 505 2.0E-69 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR00418 DNA topoisomerase II family signature 527 539 2.0E-69 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR00418 DNA topoisomerase II family signature 270 283 2.0E-69 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR00418 DNA topoisomerase II family signature 735 751 2.0E-69 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR00418 DNA topoisomerase II family signature 507 524 2.0E-69 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR00418 DNA topoisomerase II family signature 422 436 2.0E-69 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR00418 DNA topoisomerase II family signature 73 86 2.0E-69 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR00418 DNA topoisomerase II family signature 38 53 2.0E-69 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR00418 DNA topoisomerase II family signature 116 130 2.0E-69 T 14-10-2018 HL41_02005 9071255759e548e7d3be0a074df895a3 803 ProSitePatterns PS00177 DNA topoisomerase II signature. 424 432 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HL41_02005 9071255759e548e7d3be0a074df895a3 803 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 731 791 7.3E-29 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 Gene3D G3DSA:3.40.50.670 400 613 8.1E-72 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HL41_02005 9071255759e548e7d3be0a074df895a3 803 Gene3D G3DSA:3.40.50.670 689 803 2.1E-26 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HL41_02005 9071255759e548e7d3be0a074df895a3 803 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 9 803 1.1E-290 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 183 198 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 756 768 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 772 788 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 222 244 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 198 211 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 362 376 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 472 481 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 314 330 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 376 396 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 PRINTS PR01159 DNA gyrase subunit B signature 9 19 1.9E-65 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HL41_02005 9071255759e548e7d3be0a074df895a3 803 Pfam PF00204 DNA gyrase B 223 392 5.6E-62 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HL41_02005 9071255759e548e7d3be0a074df895a3 803 Pfam PF01751 Toprim domain 421 524 2.1E-19 T 14-10-2018 IPR006171 TOPRIM domain HL41_02005 9071255759e548e7d3be0a074df895a3 803 Gene3D G3DSA:3.30.565.10 6 222 4.7E-92 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_02005 9071255759e548e7d3be0a074df895a3 803 SUPERFAMILY SSF54211 223 393 4.93E-57 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Gene3D G3DSA:3.30.56.10 404 475 6.6E-19 T 14-10-2018 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Gene3D G3DSA:2.40.50.140 38 155 1.1E-39 T 14-10-2018 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Gene3D G3DSA:3.50.40.10 200 396 1.4E-78 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Pfam PF03484 tRNA synthetase B5 domain 408 470 5.7E-15 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Gene3D G3DSA:3.30.56.10 1 180 1.1E-39 T 14-10-2018 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 SUPERFAMILY SSF56037 205 396 4.71E-68 T 14-10-2018 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 SMART SM00896 707 800 8.5E-31 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 SUPERFAMILY SSF54991 703 800 8.24E-26 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 SUPERFAMILY SSF46955 405 474 1.28E-12 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Pfam PF03147 Ferredoxin-fold anticodon binding domain 707 800 1.2E-23 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Gene3D G3DSA:3.30.70.380 708 800 1.5E-22 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 798 3.3E-210 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Gene3D G3DSA:3.30.930.10 491 693 2.7E-56 T 14-10-2018 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 SUPERFAMILY SSF55681 466 692 2.21E-46 T 14-10-2018 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 SMART SM00873 213 386 5.1E-84 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 SUPERFAMILY SSF50249 43 189 7.37E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 794 37.524 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 SMART SM00874 403 470 8.7E-18 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 HL41_05960 39473176c4468a5290720f5ecefe0b48 800 Pfam PF03483 B3/4 domain 214 385 7.1E-65 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HL41_08550 5bebf4bb5d046d60785e76c899951fd2 143 Pfam PF01842 ACT domain 5 61 4.2E-8 T 14-10-2018 IPR002912 ACT domain HL41_08550 5bebf4bb5d046d60785e76c899951fd2 143 SUPERFAMILY SSF55021 72 141 1.73E-13 T 14-10-2018 HL41_08550 5bebf4bb5d046d60785e76c899951fd2 143 Gene3D G3DSA:3.30.2130.10 1 143 1.3E-53 T 14-10-2018 HL41_08550 5bebf4bb5d046d60785e76c899951fd2 143 SUPERFAMILY SSF55021 1 68 3.05E-16 T 14-10-2018 HL41_00275 504941281a2c1a034fa0d0fa577bee4b 304 Gene3D G3DSA:3.40.50.10800 88 302 9.8E-114 T 14-10-2018 HL41_00275 504941281a2c1a034fa0d0fa577bee4b 304 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 1 303 1.8E-104 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HL41_00275 504941281a2c1a034fa0d0fa577bee4b 304 SUPERFAMILY SSF142754 5 303 2.62E-112 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HL41_00275 504941281a2c1a034fa0d0fa577bee4b 304 Gene3D G3DSA:3.40.50.10800 8 284 9.8E-114 T 14-10-2018 HL41_00275 504941281a2c1a034fa0d0fa577bee4b 304 Gene3D G3DSA:3.40.50.10800 172 259 9.8E-114 T 14-10-2018 HL41_00275 504941281a2c1a034fa0d0fa577bee4b 304 Pfam PF02445 Quinolinate synthetase A protein 8 302 4.3E-117 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HL41_00275 504941281a2c1a034fa0d0fa577bee4b 304 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 303 42.933 T 14-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HL41_09010 f2c4730de9fb51b49bcd5e9058027877 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 2.0E-27 T 14-10-2018 HL41_09010 f2c4730de9fb51b49bcd5e9058027877 89 Pfam PF00312 Ribosomal protein S15 8 87 1.3E-38 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_09010 f2c4730de9fb51b49bcd5e9058027877 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 4.6E-38 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_09010 f2c4730de9fb51b49bcd5e9058027877 89 SUPERFAMILY SSF47060 3 89 7.36E-36 T 14-10-2018 IPR009068 S15/NS1, RNA-binding HL41_09010 f2c4730de9fb51b49bcd5e9058027877 89 Gene3D G3DSA:1.10.287.10 1 89 2.3E-37 T 14-10-2018 HL41_09010 f2c4730de9fb51b49bcd5e9058027877 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.66 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_09010 f2c4730de9fb51b49bcd5e9058027877 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_09010 f2c4730de9fb51b49bcd5e9058027877 89 SMART SM01387 8 88 2.4E-50 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_00050 c610da07f0964ef396978a1604d24eb8 133 SUPERFAMILY SSF54631 4 123 5.18E-30 T 14-10-2018 HL41_00050 c610da07f0964ef396978a1604d24eb8 133 Gene3D G3DSA:3.10.580.10 3 133 1.2E-32 T 14-10-2018 HL41_00050 c610da07f0964ef396978a1604d24eb8 133 SMART SM00116 12 61 5.0E-4 T 14-10-2018 IPR000644 CBS domain HL41_00050 c610da07f0964ef396978a1604d24eb8 133 SMART SM00116 79 127 3.3E-7 T 14-10-2018 IPR000644 CBS domain HL41_00050 c610da07f0964ef396978a1604d24eb8 133 Pfam PF00571 CBS domain 72 123 9.0E-13 T 14-10-2018 IPR000644 CBS domain HL41_00050 c610da07f0964ef396978a1604d24eb8 133 Pfam PF00571 CBS domain 5 60 8.6E-10 T 14-10-2018 IPR000644 CBS domain HL41_00450 d9498c31ba3ab8a1fa4d0f7277cfbbed 85 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 24.312 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_00450 d9498c31ba3ab8a1fa4d0f7277cfbbed 85 Pfam PF00886 Ribosomal protein S16 9 67 3.6E-24 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_00450 d9498c31ba3ab8a1fa4d0f7277cfbbed 85 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 1.0E-32 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_00450 d9498c31ba3ab8a1fa4d0f7277cfbbed 85 Gene3D G3DSA:3.30.1320.10 1 85 4.2E-33 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_00450 d9498c31ba3ab8a1fa4d0f7277cfbbed 85 SUPERFAMILY SSF54565 3 79 2.62E-31 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01535 1f2a9a4379620ca11d56b6862ea221ca 353 SUPERFAMILY SSF52540 1 216 3.01E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01535 1f2a9a4379620ca11d56b6862ea221ca 353 Pfam PF07085 DRTGG domain 214 318 7.0E-26 T 14-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HL41_01535 1f2a9a4379620ca11d56b6862ea221ca 353 SUPERFAMILY SSF75138 209 322 1.15E-27 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HL41_01535 1f2a9a4379620ca11d56b6862ea221ca 353 Gene3D G3DSA:3.40.1390.20 202 340 2.2E-42 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HL41_01535 1f2a9a4379620ca11d56b6862ea221ca 353 Pfam PF13500 AAA domain 2 209 1.4E-12 T 14-10-2018 HL41_09070 f992470b65394efad57cc2fcf1972230 175 PIRSF PIRSF039093 1 175 1.2E-87 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 HL41_09070 f992470b65394efad57cc2fcf1972230 175 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 5 175 1.2E-83 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 HL41_09070 f992470b65394efad57cc2fcf1972230 175 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 4 175 41.472 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 HL41_09070 f992470b65394efad57cc2fcf1972230 175 Pfam PF00227 Proteasome subunit 1 173 1.7E-28 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 HL41_09070 f992470b65394efad57cc2fcf1972230 175 SUPERFAMILY SSF56235 1 174 1.16E-59 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HL41_09070 f992470b65394efad57cc2fcf1972230 175 Gene3D G3DSA:3.60.20.10 1 175 1.8E-68 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 193 2.3E-79 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 SUPERFAMILY SSF52402 182 434 1.21E-58 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 202 513 1.4E-151 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 Gene3D G3DSA:3.40.50.880 1 194 8.8E-60 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 Pfam PF00117 Glutamine amidotransferase class-I 7 189 1.2E-41 T 14-10-2018 IPR017926 Glutamine amidotransferase HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 PRINTS PR00097 Anthranilate synthase component II signature 76 87 2.2E-7 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 PRINTS PR00097 Anthranilate synthase component II signature 166 179 2.2E-7 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 PRINTS PR00097 Anthranilate synthase component II signature 49 58 2.2E-7 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 Pfam PF02540 NAD synthase 203 281 5.0E-7 T 14-10-2018 IPR022310 NAD/GMP synthase HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 Pfam PF00958 GMP synthase C terminal domain 421 512 8.2E-46 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 Gene3D G3DSA:3.40.50.620 198 393 6.8E-77 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 SUPERFAMILY SSF52317 2 227 5.26E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 Gene3D G3DSA:3.30.300.10 394 513 4.2E-55 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 3.4E-8 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 3.4E-8 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 76 87 3.4E-8 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 SUPERFAMILY SSF54810 393 513 4.18E-54 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 1.1E-5 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 76 92 1.1E-5 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 5 19 1.1E-5 T 14-10-2018 HL41_00750 eae3741b1cf73fcf79cad6c8c54c3761 513 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 513 55.865 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 HL41_01915 0c728877ce777d96152d7aff9e226b9c 785 Gene3D G3DSA:1.10.8.630 2 110 4.7E-24 T 14-10-2018 HL41_01915 0c728877ce777d96152d7aff9e226b9c 785 SUPERFAMILY SSF52540 513 681 7.34E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01915 0c728877ce777d96152d7aff9e226b9c 785 SMART SM00490 546 643 9.2E-5 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_01915 0c728877ce777d96152d7aff9e226b9c 785 SUPERFAMILY SSF52540 190 439 3.4E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01915 0c728877ce777d96152d7aff9e226b9c 785 Hamap MF_00983 Probable primosomal protein N' [priA]. 6 784 23.517 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HL41_01915 0c728877ce777d96152d7aff9e226b9c 785 Gene3D G3DSA:3.40.50.300 243 437 4.4E-63 T 14-10-2018 HL41_01915 0c728877ce777d96152d7aff9e226b9c 785 Pfam PF04851 Type III restriction enzyme, res subunit 252 417 5.6E-10 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HL41_01915 0c728877ce777d96152d7aff9e226b9c 785 SMART SM00487 250 449 7.6E-14 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HL41_01915 0c728877ce777d96152d7aff9e226b9c 785 TIGRFAM TIGR00595 priA: primosomal protein N' 278 781 1.9E-166 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 321 35.588 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 Gene3D G3DSA:1.10.1040.10 188 335 4.4E-54 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 179 319 6.4E-52 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 158 1.0E-43 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 SUPERFAMILY SSF51735 1 179 2.02E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 187 208 - T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 237 254 3.5E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 197 221 3.5E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 172 196 3.5E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 3.5E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 132 152 3.5E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 3.5E-44 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 Gene3D G3DSA:3.40.50.720 1 186 1.1E-57 T 14-10-2018 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 SUPERFAMILY SSF48179 178 331 3.74E-55 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HL41_04115 c2b131a64cbeb2b1656301b3d9556cf3 338 PIRSF PIRSF000114 1 331 3.3E-108 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 HL41_02920 a7fda7b5f5d7ab5853882b386c166ede 532 Pfam PF02652 L-lactate permease 2 526 5.0E-47 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 502 5.7E-249 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 Gene3D G3DSA:2.40.30.20 2 95 1.1E-31 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 SUPERFAMILY SSF52540 98 372 5.55E-99 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 151 366 1.5E-74 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 357 366 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 Gene3D G3DSA:3.40.50.300 96 373 4.5E-126 T 14-10-2018 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 503 50.003 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 373 498 1.1E-50 T 14-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 94 4.7E-12 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 Gene3D G3DSA:1.20.150.20 374 508 2.3E-52 T 14-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 SUPERFAMILY SSF50615 11 96 1.83E-24 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 SUPERFAMILY SSF47917 374 502 7.32E-47 T 14-10-2018 HL41_01085 abd8e102875ed11d11ef6e5dee45c7b7 514 PIRSF PIRSF039088 2 505 1.1E-256 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_02210 1365019212aff0724be9be3ee602c1ad 227 Pfam PF13483 Beta-lactamase superfamily domain 3 189 4.0E-29 T 14-10-2018 HL41_02210 1365019212aff0724be9be3ee602c1ad 227 SUPERFAMILY SSF56281 1 225 3.54E-37 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_02210 1365019212aff0724be9be3ee602c1ad 227 Gene3D G3DSA:3.60.15.10 1 227 8.2E-69 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_02210 1365019212aff0724be9be3ee602c1ad 227 SMART SM00849 7 189 1.9E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_02210 1365019212aff0724be9be3ee602c1ad 227 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 227 38.021 T 14-10-2018 IPR022877 Protein of unknown funcion UPF0173 HL41_05380 bdc66c36ef673c1d4d82a71509bffbed 61 SUPERFAMILY SSF57716 8 61 1.07E-19 T 14-10-2018 HL41_05380 bdc66c36ef673c1d4d82a71509bffbed 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 24.555 T 14-10-2018 IPR023053 Ribosomal protein S14, type Z HL41_05380 bdc66c36ef673c1d4d82a71509bffbed 61 Gene3D G3DSA:4.10.830.10 1 61 6.6E-28 T 14-10-2018 HL41_05380 bdc66c36ef673c1d4d82a71509bffbed 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 14-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05380 bdc66c36ef673c1d4d82a71509bffbed 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 3.1E-23 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 302 5.2E-62 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 SUPERFAMILY SSF52821 447 556 6.58E-19 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 SUPERFAMILY SSF55424 333 457 1.72E-14 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 245 259 1.6E-10 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 183 1.6E-10 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 1.6E-10 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.6E-10 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 397 412 1.6E-10 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 SUPERFAMILY SSF51905 1 351 1.34E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 1.2E-23 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 1.2E-23 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 1.2E-23 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 1.2E-23 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.2E-23 T 14-10-2018 HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 Gene3D G3DSA:3.50.50.60 120 452 3.7E-147 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 Gene3D G3DSA:3.40.250.10 463 567 1.9E-16 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 Gene3D G3DSA:3.50.50.60 2 350 3.7E-147 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_07210 da15d0e4aecd69ea1490c59ec9471542 567 SMART SM00450 466 565 1.8E-6 T 14-10-2018 IPR001763 Rhodanese-like domain HL41_09115 e7f3ebeff06f70abd3e6fc9010c6fd83 476 Gene3D G3DSA:3.90.1860.10 3 476 2.2E-188 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 HL41_09115 e7f3ebeff06f70abd3e6fc9010c6fd83 476 SUPERFAMILY SSF103365 5 476 4.84E-164 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 HL41_09115 e7f3ebeff06f70abd3e6fc9010c6fd83 476 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 45 74 - T 14-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 HL41_09115 e7f3ebeff06f70abd3e6fc9010c6fd83 476 Pfam PF01139 tRNA-splicing ligase RtcB 45 476 2.4E-157 T 14-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Gene3D G3DSA:3.40.50.2300 770 898 7.5E-37 T 14-10-2018 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 474 9.3E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SUPERFAMILY SSF47384 229 288 9.81E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Gene3D G3DSA:2.40.50.180 655 717 1.7E-9 T 14-10-2018 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Gene3D G3DSA:2.40.50.180 498 561 1.5E-37 T 14-10-2018 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SMART SM00260 632 760 1.6E-4 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SMART SM00260 467 606 3.0E-26 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Gene3D G3DSA:1.10.287.560 228 286 1.4E-18 T 14-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Pfam PF01584 CheW-like domain 480 605 5.9E-21 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Pfam PF01584 CheW-like domain 637 761 1.5E-9 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SUPERFAMILY SSF47226 3 114 1.12E-26 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Gene3D G3DSA:1.20.120.160 4 142 5.4E-33 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SMART SM01231 227 287 2.2E-16 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 230 287 4.4E-13 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 429 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SMART SM00448 780 893 5.0E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SUPERFAMILY SSF55874 290 473 9.3E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Pfam PF00072 Response regulator receiver domain 782 892 5.8E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SUPERFAMILY SSF52172 780 897 8.11E-34 T 14-10-2018 IPR011006 CheY-like superfamily HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SMART SM00073 4 101 2.1E-18 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Gene3D G3DSA:2.30.30.40 638 755 1.7E-9 T 14-10-2018 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SUPERFAMILY SSF50341 474 605 1.83E-27 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SUPERFAMILY SSF50341 637 759 7.46E-15 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Gene3D G3DSA:2.30.30.40 475 602 1.5E-37 T 14-10-2018 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Pfam PF01627 Hpt domain 6 94 2.3E-12 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 Gene3D G3DSA:3.30.565.10 287 474 2.0E-62 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_02985 2f1126c26c08efbe73fcae3533e966b7 898 SMART SM00387 332 475 6.4E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 Pfam PF02881 SRP54-type protein, helical bundle domain 15 81 2.5E-7 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 Gene3D G3DSA:1.20.120.140 3 298 1.2E-104 T 14-10-2018 HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 Gene3D G3DSA:3.40.50.300 99 288 1.2E-104 T 14-10-2018 HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 SUPERFAMILY SSF47364 2 79 1.31E-15 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 SUPERFAMILY SSF52540 95 299 4.26E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 273 286 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 Pfam PF00448 SRP54-type protein, GTPase domain 99 299 1.1E-76 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 SMART SM00963 5 86 9.3E-11 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 33 299 5.2E-101 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 SMART SM00382 98 276 1.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 SMART SM00962 99 300 6.1E-114 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_08385 7c1e1d0942468d93279a92c32a5fbf50 301 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 29 300 57.217 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 Gene3D G3DSA:2.40.340.10 329 403 1.6E-17 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 Pfam PF00994 Probable molybdopterin binding domain 177 317 7.8E-18 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 Gene3D G3DSA:3.40.190.10 494 584 1.2E-7 T 14-10-2018 HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 SUPERFAMILY SSF63882 10 172 5.36E-42 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 Pfam PF12727 PBP superfamily domain 428 615 5.2E-71 T 14-10-2018 IPR024370 PBP domain HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 Gene3D G3DSA:2.170.190.11 57 138 2.0E-79 T 14-10-2018 HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 Pfam PF03454 MoeA C-terminal region (domain IV) 333 401 6.4E-14 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 Pfam PF03453 MoeA N-terminal region (domain I and II) 11 164 9.1E-36 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 SMART SM00852 177 318 2.5E-29 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 Gene3D G3DSA:3.40.980.10 172 316 2.0E-79 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 SUPERFAMILY SSF53850 431 631 8.61E-21 T 14-10-2018 HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 SUPERFAMILY SSF63867 330 402 2.62E-16 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 SUPERFAMILY SSF53218 172 321 9.03E-31 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily HL41_08570 f0aaf905a88f728912e4da261470e3c9 643 Gene3D G3DSA:3.90.105.10 34 171 2.0E-79 T 14-10-2018 HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 Gene3D G3DSA:3.40.50.920 519 647 2.2E-26 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 Gene3D G3DSA:3.40.50.970 322 507 7.4E-45 T 14-10-2018 HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 Pfam PF02779 Transketolase, pyrimidine binding domain 353 497 8.0E-16 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 Pfam PF02780 Transketolase, C-terminal domain 519 638 5.6E-20 T 14-10-2018 IPR033248 Transketolase, C-terminal domain HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 Gene3D G3DSA:3.40.50.970 17 310 1.2E-83 T 14-10-2018 HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 SUPERFAMILY SSF52922 516 647 1.13E-23 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 37 291 1.2E-46 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 SUPERFAMILY SSF52518 11 302 2.46E-68 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 SUPERFAMILY SSF52518 323 501 1.07E-33 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold HL41_05665 1f75f8fc6611488e3d7f457c63925e95 647 SMART SM00861 330 500 2.8E-24 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HL41_08660 9cbe124f206432ccb419b32ea2d731c0 171 Gene3D G3DSA:3.40.50.12280 15 171 4.3E-77 T 14-10-2018 HL41_08660 9cbe124f206432ccb419b32ea2d731c0 171 SUPERFAMILY SSF56770 25 168 2.22E-68 T 14-10-2018 HL41_08660 9cbe124f206432ccb419b32ea2d731c0 171 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 27 166 6.4E-74 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08660 9cbe124f206432ccb419b32ea2d731c0 171 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 16 166 44.097 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08660 9cbe124f206432ccb419b32ea2d731c0 171 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 53 161 2.3E-26 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_05880 c7b59fcf19c51f269cbeacad08c3d9ad 307 Pfam PF00849 RNA pseudouridylate synthase 92 245 1.1E-29 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05880 c7b59fcf19c51f269cbeacad08c3d9ad 307 Gene3D G3DSA:3.10.290.10 6 73 3.5E-21 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HL41_05880 c7b59fcf19c51f269cbeacad08c3d9ad 307 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 303 2.3E-87 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05880 c7b59fcf19c51f269cbeacad08c3d9ad 307 Gene3D G3DSA:3.30.2350.10 85 307 8.2E-72 T 14-10-2018 HL41_05880 c7b59fcf19c51f269cbeacad08c3d9ad 307 SUPERFAMILY SSF55120 79 304 1.25E-73 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05880 c7b59fcf19c51f269cbeacad08c3d9ad 307 Pfam PF01479 S4 domain 20 65 8.8E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05880 c7b59fcf19c51f269cbeacad08c3d9ad 307 SMART SM00363 19 76 8.8E-12 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05880 c7b59fcf19c51f269cbeacad08c3d9ad 307 SUPERFAMILY SSF55174 19 105 1.68E-13 T 14-10-2018 HL41_05880 c7b59fcf19c51f269cbeacad08c3d9ad 307 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 SUPERFAMILY SSF64153 1 256 2.62E-65 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 238 515 2.8E-66 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 Gene3D G3DSA:3.40.1190.20 229 519 7.7E-81 T 14-10-2018 IPR029056 Ribokinase-like HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 219 27.019 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 SUPERFAMILY SSF53613 231 517 3.62E-71 T 14-10-2018 IPR029056 Ribokinase-like HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 234 519 22.094 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 PIRSF PIRSF017184 1 521 2.7E-139 T 14-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 2 219 1.8E-50 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 454 464 - T 14-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 Pfam PF01256 Carbohydrate kinase 257 511 3.1E-53 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 Pfam PF03853 YjeF-related protein N-terminus 25 198 2.3E-45 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HL41_00185 f6fb3d6caa3ee6bc78bccf3d72e998fd 522 Gene3D G3DSA:3.40.50.10260 1 225 5.3E-70 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 HL41_05615 29eaf59a4e5c9e8997916b8175a9ef44 268 Gene3D G3DSA:3.30.70.580 4 110 1.6E-35 T 14-10-2018 HL41_05615 29eaf59a4e5c9e8997916b8175a9ef44 268 SUPERFAMILY SSF55120 5 256 5.9E-87 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05615 29eaf59a4e5c9e8997916b8175a9ef44 268 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 7 247 7.7E-64 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05615 29eaf59a4e5c9e8997916b8175a9ef44 268 PIRSF PIRSF001430 6 263 1.2E-86 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05615 29eaf59a4e5c9e8997916b8175a9ef44 268 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 7 252 35.305 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05615 29eaf59a4e5c9e8997916b8175a9ef44 268 Pfam PF01416 tRNA pseudouridine synthase 153 252 8.0E-28 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05615 29eaf59a4e5c9e8997916b8175a9ef44 268 Pfam PF01416 tRNA pseudouridine synthase 13 106 1.9E-10 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05615 29eaf59a4e5c9e8997916b8175a9ef44 268 Gene3D G3DSA:3.30.70.660 111 251 2.0E-48 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 SMART SM00382 363 508 2.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 SMART SM00464 23 217 1.1E-53 T 14-10-2018 IPR003111 Lon, substrate-binding domain HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 688 707 4.2E-52 T 14-10-2018 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 610 626 4.2E-52 T 14-10-2018 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 741 759 4.2E-52 T 14-10-2018 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 371 390 4.2E-52 T 14-10-2018 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 718 737 4.2E-52 T 14-10-2018 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 TIGRFAM TIGR00763 lon: endopeptidase La 25 785 3.3E-300 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 367 505 3.9E-21 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 SUPERFAMILY SSF52540 325 602 1.08E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 Gene3D G3DSA:2.30.130.40 17 128 1.3E-31 T 14-10-2018 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 Hamap MF_01973 Lon protease [lon]. 24 787 70.421 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 Gene3D G3DSA:1.10.8.60 506 599 3.1E-32 T 14-10-2018 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 SUPERFAMILY SSF88697 23 215 1.79E-39 T 14-10-2018 IPR015947 PUA-like superfamily HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 Gene3D G3DSA:3.30.230.10 608 788 1.2E-81 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 SUPERFAMILY SSF54211 610 785 5.31E-58 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 PIRSF PIRSF001174 11 788 0.0 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 Gene3D G3DSA:1.20.58.1480 135 261 1.7E-34 T 14-10-2018 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 Gene3D G3DSA:3.40.50.300 328 505 7.3E-66 T 14-10-2018 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 23 215 3.6E-36 T 14-10-2018 IPR003111 Lon, substrate-binding domain HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 585 786 4.7E-91 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HL41_04640 aef40b33abfdfda11e5d496f149bc243 788 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 691 699 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 Gene3D G3DSA:3.50.30.10 363 470 5.0E-44 T 14-10-2018 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 805 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 PIRSF PIRSF000854 2 809 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 SUPERFAMILY SSF56059 5 388 2.83E-107 T 14-10-2018 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 20 345 5.2E-119 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 SUPERFAMILY SSF51621 471 807 4.71E-100 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 Gene3D G3DSA:3.30.470.20 197 362 4.6E-55 T 14-10-2018 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 Gene3D G3DSA:3.20.20.60 484 805 1.1E-102 T 14-10-2018 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 420 431 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 Gene3D G3DSA:3.30.1490.20 4 196 3.4E-77 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 Pfam PF00391 PEP-utilising enzyme, mobile domain 390 461 6.2E-28 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 709 727 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 SUPERFAMILY SSF52009 352 463 1.44E-33 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 484 803 4.1E-67 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 726 741 6.3E-7 T 14-10-2018 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 709 724 6.3E-7 T 14-10-2018 HL41_06185 90d73221f9edf64a50ff9c064d53ec66 811 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 762 774 6.3E-7 T 14-10-2018 HL41_01880 d36306a1b3cead3ac7c8d860534e9964 338 Gene3D G3DSA:2.30.30.280 198 258 1.5E-14 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 HL41_01880 d36306a1b3cead3ac7c8d860534e9964 338 Pfam PF03054 tRNA methyl transferase 1 334 3.1E-100 T 14-10-2018 HL41_01880 d36306a1b3cead3ac7c8d860534e9964 338 Gene3D G3DSA:2.40.30.10 264 338 5.0E-14 T 14-10-2018 HL41_01880 d36306a1b3cead3ac7c8d860534e9964 338 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 334 3.6E-94 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 HL41_01880 d36306a1b3cead3ac7c8d860534e9964 338 Gene3D G3DSA:3.40.50.620 1 197 9.4E-64 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_01880 d36306a1b3cead3ac7c8d860534e9964 338 SUPERFAMILY SSF52402 1 228 9.04E-39 T 14-10-2018 HL41_01880 d36306a1b3cead3ac7c8d860534e9964 338 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 335 33.076 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 HL41_09020 feac2d52a2b68a17b6c42bfd4504a4bc 90 Gene3D G3DSA:3.30.70.100 1 89 1.9E-35 T 14-10-2018 HL41_09020 feac2d52a2b68a17b6c42bfd4504a4bc 90 PRINTS PR00112 Acylphosphatase signature 24 49 6.2E-7 T 14-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HL41_09020 feac2d52a2b68a17b6c42bfd4504a4bc 90 PRINTS PR00112 Acylphosphatase signature 3 18 6.2E-7 T 14-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HL41_09020 feac2d52a2b68a17b6c42bfd4504a4bc 90 Pfam PF00708 Acylphosphatase 4 88 2.9E-29 T 14-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HL41_09020 feac2d52a2b68a17b6c42bfd4504a4bc 90 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 14-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HL41_09020 feac2d52a2b68a17b6c42bfd4504a4bc 90 SUPERFAMILY SSF54975 1 89 2.62E-32 T 14-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HL41_09020 feac2d52a2b68a17b6c42bfd4504a4bc 90 ProSitePatterns PS00151 Acylphosphatase signature 2. 32 48 - T 14-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HL41_04810 b9369ea174b32b6840984673e4e77610 467 SUPERFAMILY SSF53623 113 319 4.45E-46 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HL41_04810 b9369ea174b32b6840984673e4e77610 467 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 462 1.5E-122 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_04810 b9369ea174b32b6840984673e4e77610 467 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 1 463 31.096 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_04810 b9369ea174b32b6840984673e4e77610 467 SUPERFAMILY SSF53244 327 462 8.47E-31 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HL41_04810 b9369ea174b32b6840984673e4e77610 467 Pfam PF08245 Mur ligase middle domain 118 303 1.8E-41 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 HL41_04810 b9369ea174b32b6840984673e4e77610 467 Gene3D G3DSA:3.40.1190.10 94 321 3.0E-61 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HL41_04810 b9369ea174b32b6840984673e4e77610 467 Pfam PF02875 Mur ligase family, glutamate ligase domain 327 404 7.0E-15 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 HL41_04810 b9369ea174b32b6840984673e4e77610 467 Pfam PF01225 Mur ligase family, catalytic domain 30 107 2.6E-10 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HL41_04810 b9369ea174b32b6840984673e4e77610 467 Gene3D G3DSA:3.90.190.20 324 466 2.8E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HL41_04810 b9369ea174b32b6840984673e4e77610 467 SUPERFAMILY SSF63418 10 110 2.09E-21 T 14-10-2018 IPR035911 MurE/MurF, N-terminal HL41_04810 b9369ea174b32b6840984673e4e77610 467 Gene3D G3DSA:3.40.1390.10 5 85 2.1E-19 T 14-10-2018 HL41_05965 bee2488bd2d7ce30f2d4fc28e2381453 337 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 41 337 3.3E-98 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 HL41_05965 bee2488bd2d7ce30f2d4fc28e2381453 337 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 22 81 1.8E-18 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HL41_05965 bee2488bd2d7ce30f2d4fc28e2381453 337 SUPERFAMILY SSF46589 16 98 1.99E-17 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 HL41_05965 bee2488bd2d7ce30f2d4fc28e2381453 337 Gene3D G3DSA:3.30.930.10 9 337 2.7E-115 T 14-10-2018 HL41_05965 bee2488bd2d7ce30f2d4fc28e2381453 337 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 10 336 45.316 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 HL41_05965 bee2488bd2d7ce30f2d4fc28e2381453 337 Pfam PF01409 tRNA synthetases class II core domain (F) 91 336 3.8E-100 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 HL41_05965 bee2488bd2d7ce30f2d4fc28e2381453 337 SUPERFAMILY SSF55681 91 337 1.43E-76 T 14-10-2018 HL41_08590 6d41b63b0ca4195e38bb0ba630f63c90 187 Gene3D G3DSA:3.40.50.740 99 187 9.2E-41 T 14-10-2018 HL41_08590 6d41b63b0ca4195e38bb0ba630f63c90 187 SMART SM00926 42 96 4.8E-23 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08590 6d41b63b0ca4195e38bb0ba630f63c90 187 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 43 96 2.0E-21 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08590 6d41b63b0ca4195e38bb0ba630f63c90 187 Pfam PF00384 Molybdopterin oxidoreductase 99 177 9.5E-6 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08590 6d41b63b0ca4195e38bb0ba630f63c90 187 Gene3D G3DSA:2.20.25.90 39 97 2.3E-22 T 14-10-2018 HL41_08590 6d41b63b0ca4195e38bb0ba630f63c90 187 SUPERFAMILY SSF53706 35 187 2.36E-62 T 14-10-2018 HL41_03150 9beb579ba352a35bfb6f446fb87bfee9 96 Gene3D G3DSA:3.30.70.1120 1 96 6.8E-26 T 14-10-2018 IPR036746 TT1725-like superfamily HL41_03150 9beb579ba352a35bfb6f446fb87bfee9 96 SUPERFAMILY SSF103007 1 94 2.75E-23 T 14-10-2018 IPR036746 TT1725-like superfamily HL41_03150 9beb579ba352a35bfb6f446fb87bfee9 96 Pfam PF04456 Protein of unknown function (DUF503) 3 90 6.3E-27 T 14-10-2018 IPR007546 Protein of unknown function DUF503 HL41_03635 01b0ca03072577106a34d9437ef60783 402 Gene3D G3DSA:3.10.290.10 332 400 2.3E-17 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HL41_03635 01b0ca03072577106a34d9437ef60783 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 51 73 4.6E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HL41_03635 01b0ca03072577106a34d9437ef60783 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 166 181 4.6E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HL41_03635 01b0ca03072577106a34d9437ef60783 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 4.6E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HL41_03635 01b0ca03072577106a34d9437ef60783 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 4.6E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HL41_03635 01b0ca03072577106a34d9437ef60783 402 Gene3D G3DSA:1.10.240.10 223 331 6.9E-38 T 14-10-2018 HL41_03635 01b0ca03072577106a34d9437ef60783 402 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 57 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_03635 01b0ca03072577106a34d9437ef60783 402 Pfam PF00579 tRNA synthetases class I (W and Y) 35 322 2.1E-86 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_03635 01b0ca03072577106a34d9437ef60783 402 Gene3D G3DSA:3.40.50.620 6 222 1.6E-77 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_03635 01b0ca03072577106a34d9437ef60783 402 SUPERFAMILY SSF55174 304 401 3.93E-15 T 14-10-2018 HL41_03635 01b0ca03072577106a34d9437ef60783 402 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 6 401 2.1E-127 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HL41_03635 01b0ca03072577106a34d9437ef60783 402 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 3 401 48.322 T 14-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 HL41_03635 01b0ca03072577106a34d9437ef60783 402 SUPERFAMILY SSF52374 8 322 6.37E-98 T 14-10-2018 HL41_01115 861fc6449e5ecda72bfd81c4a74d17b9 812 SUPERFAMILY SSF56281 530 764 4.06E-28 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_01115 861fc6449e5ecda72bfd81c4a74d17b9 812 Gene3D G3DSA:3.60.15.10 528 768 2.9E-40 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_01115 861fc6449e5ecda72bfd81c4a74d17b9 812 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 237 433 1.1E-12 T 14-10-2018 IPR004477 ComEC/Rec2-related protein HL41_01115 861fc6449e5ecda72bfd81c4a74d17b9 812 Pfam PF03772 Competence protein 215 498 1.9E-32 T 14-10-2018 IPR004477 ComEC/Rec2-related protein HL41_01115 861fc6449e5ecda72bfd81c4a74d17b9 812 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 190 759 3.5E-57 T 14-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 HL41_01115 861fc6449e5ecda72bfd81c4a74d17b9 812 Pfam PF00753 Metallo-beta-lactamase superfamily 534 611 5.8E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 TIGRFAM TIGR01817 nifA: Nif-specific regulatory protein 15 510 1.8E-159 T 14-10-2018 IPR010113 Nif-specific regulatory protein GO:0003700|GO:0006355|GO:0009399 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 SMART SM00382 220 363 7.2E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 SMART SM00065 32 181 1.7E-17 T 14-10-2018 IPR003018 GAF domain GO:0005515 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 Gene3D G3DSA:3.40.50.300 188 370 1.4E-69 T 14-10-2018 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 SUPERFAMILY SSF46689 412 510 1.43E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 Pfam PF01590 GAF domain 34 169 7.2E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 Gene3D G3DSA:1.10.8.60 371 447 2.1E-29 T 14-10-2018 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 Pfam PF00158 Sigma-54 interaction domain 200 366 7.7E-72 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 Pfam PF02954 Bacterial regulatory protein, Fis family 468 508 1.5E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 224 237 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 474 491 6.9E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 491 511 6.9E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 Gene3D G3DSA:3.30.450.40 10 183 3.2E-55 T 14-10-2018 IPR029016 GAF-like domain superfamily HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 Gene3D G3DSA:1.10.10.60 448 512 1.7E-15 T 14-10-2018 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 SUPERFAMILY SSF52540 199 442 3.92E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 412 421 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 286 301 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HL41_03985 cbda02a65324c0e5a248d5a317a9a206 513 SUPERFAMILY SSF55781 4 171 8.51E-29 T 14-10-2018 HL41_03410 4d257d94ab0647c8f531e9a46467fca0 315 Gene3D G3DSA:3.30.1360.170 190 315 5.6E-22 T 14-10-2018 HL41_03410 4d257d94ab0647c8f531e9a46467fca0 315 Pfam PF02511 Thymidylate synthase complementing protein 196 313 2.1E-21 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 HL41_03410 4d257d94ab0647c8f531e9a46467fca0 315 SUPERFAMILY SSF69796 32 314 3.92E-22 T 14-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 HL41_02705 0f407400c0397bad4f120c66f2401c44 228 SUPERFAMILY SSF53167 51 225 6.02E-24 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 HL41_02705 0f407400c0397bad4f120c66f2401c44 228 Pfam PF01048 Phosphorylase superfamily 56 223 3.9E-12 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HL41_02705 0f407400c0397bad4f120c66f2401c44 228 Gene3D G3DSA:3.40.50.1580 24 226 1.9E-23 T 14-10-2018 HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 SUPERFAMILY SSF52540 576 779 4.77E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 Gene3D G3DSA:2.40.50.140 168 265 9.6E-19 T 14-10-2018 HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 SUPERFAMILY SSF52540 306 575 1.45E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 Gene3D G3DSA:3.40.50.300 334 573 1.4E-89 T 14-10-2018 HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 Pfam PF17191 RecG wedge domain 131 295 4.4E-36 T 14-10-2018 IPR033454 RecG, wedge domain HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 SMART SM00487 390 582 2.2E-34 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 Pfam PF00270 DEAD/DEAH box helicase 396 554 5.4E-18 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 Gene3D G3DSA:3.40.50.300 581 754 1.1E-59 T 14-10-2018 HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 SMART SM00490 627 712 1.5E-22 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 SUPERFAMILY SSF50249 125 301 2.68E-48 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 151 789 4.3E-239 T 14-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 HL41_04695 6a28fe95d4df3a0741b60cc1f2bc26c4 823 Pfam PF00271 Helicase conserved C-terminal domain 597 711 1.0E-19 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 Pfam PF01025 GrpE 5 174 9.5E-49 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 SUPERFAMILY SSF51064 122 175 3.01E-15 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 Gene3D G3DSA:2.30.22.10 118 174 5.6E-18 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 SUPERFAMILY SSF58014 22 118 2.09E-24 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 Hamap MF_01151 Protein GrpE [grpE]. 2 175 19.555 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 PRINTS PR00773 GrpE protein signature 154 173 4.6E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 PRINTS PR00773 GrpE protein signature 127 142 4.6E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 PRINTS PR00773 GrpE protein signature 44 60 4.6E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 PRINTS PR00773 GrpE protein signature 72 87 4.6E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HL41_01155 5324f46242ca1f93f7fe5145c4df9e88 200 Gene3D G3DSA:3.90.20.20 1 117 3.6E-23 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 HL41_04055 4f49efd5eebe5517c042a0884e12ba6f 266 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 8 259 31.541 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 HL41_04055 4f49efd5eebe5517c042a0884e12ba6f 266 SUPERFAMILY SSF51366 6 257 2.71E-75 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HL41_04055 4f49efd5eebe5517c042a0884e12ba6f 266 Gene3D G3DSA:3.20.20.70 3 265 6.9E-91 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_04055 4f49efd5eebe5517c042a0884e12ba6f 266 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 35 255 29.322 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 HL41_04055 4f49efd5eebe5517c042a0884e12ba6f 266 Pfam PF00218 Indole-3-glycerol phosphate synthase 35 256 1.5E-76 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 HL41_03245 5c5ca92ca91425feb1b628dcc8978ba0 295 SUPERFAMILY SSF53633 3 291 8.64E-97 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HL41_03245 5c5ca92ca91425feb1b628dcc8978ba0 295 Hamap MF_00082 Acetylglutamate kinase [argB]. 22 285 52.127 T 14-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HL41_03245 5c5ca92ca91425feb1b628dcc8978ba0 295 TIGRFAM TIGR00761 argB: acetylglutamate kinase 25 267 6.7E-84 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HL41_03245 5c5ca92ca91425feb1b628dcc8978ba0 295 PIRSF PIRSF000728 5 291 3.5E-112 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HL41_03245 5c5ca92ca91425feb1b628dcc8978ba0 295 Gene3D G3DSA:3.40.1160.10 3 291 2.8E-101 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HL41_03245 5c5ca92ca91425feb1b628dcc8978ba0 295 Pfam PF00696 Amino acid kinase family 23 269 1.8E-48 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HL41_03245 5c5ca92ca91425feb1b628dcc8978ba0 295 PRINTS PR00474 Glutamate 5-kinase family signature 192 219 3.0E-9 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HL41_03245 5c5ca92ca91425feb1b628dcc8978ba0 295 PRINTS PR00474 Glutamate 5-kinase family signature 242 262 3.0E-9 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HL41_02895 1ee588612b5ab5bd97c5c6576bc07a1e 528 Gene3D G3DSA:3.30.70.260 14 84 6.7E-6 T 14-10-2018 HL41_02895 1ee588612b5ab5bd97c5c6576bc07a1e 528 SUPERFAMILY SSF55021 24 87 1.35E-7 T 14-10-2018 HL41_02895 1ee588612b5ab5bd97c5c6576bc07a1e 528 Pfam PF00753 Metallo-beta-lactamase superfamily 281 463 6.7E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_02895 1ee588612b5ab5bd97c5c6576bc07a1e 528 SUPERFAMILY SSF56281 278 521 1.26E-27 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_02895 1ee588612b5ab5bd97c5c6576bc07a1e 528 Gene3D G3DSA:3.60.15.10 272 524 2.2E-26 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_02895 1ee588612b5ab5bd97c5c6576bc07a1e 528 SMART SM00849 283 516 3.6E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_02895 1ee588612b5ab5bd97c5c6576bc07a1e 528 SUPERFAMILY SSF55021 96 171 8.25E-6 T 14-10-2018 HL41_05435 911fc66d9b2b5a1537931b2ac167010a 96 Pfam PF00276 Ribosomal protein L23 6 92 1.1E-30 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HL41_05435 911fc66d9b2b5a1537931b2ac167010a 96 SUPERFAMILY SSF54189 2 94 1.76E-30 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05435 911fc66d9b2b5a1537931b2ac167010a 96 ProSitePatterns PS00050 Ribosomal protein L23 signature. 78 93 - T 14-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05435 911fc66d9b2b5a1537931b2ac167010a 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 21.38 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HL41_05435 911fc66d9b2b5a1537931b2ac167010a 96 Gene3D G3DSA:3.30.70.330 1 96 7.8E-33 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 SUPERFAMILY SSF55347 131 323 5.36E-75 T 14-10-2018 HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 338 2.4E-143 T 14-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 SUPERFAMILY SSF51735 4 158 6.78E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 Gene3D G3DSA:3.30.360.10 130 319 3.5E-141 T 14-10-2018 HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 322 5.4E-54 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 3 336 36.998 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 PIRSF PIRSF000148 3 340 2.0E-130 T 14-10-2018 HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 120 1.3E-30 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 Gene3D G3DSA:3.40.50.720 6 333 3.5E-141 T 14-10-2018 HL41_02690 35b81d1513ce4b2a6d46c87eb96f1de1 340 SMART SM00859 5 121 1.4E-40 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 450 526 3.0E-4 T 14-10-2018 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 2 525 5.9E-201 T 14-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 SUPERFAMILY SSF51735 99 281 1.15E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 Gene3D G3DSA:3.40.50.720 3 290 3.3E-126 T 14-10-2018 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 9.5E-67 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 Gene3D G3DSA:3.40.50.720 92 282 3.3E-126 T 14-10-2018 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 SUPERFAMILY SSF55021 442 523 1.12E-17 T 14-10-2018 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 312 2.1E-38 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 Gene3D G3DSA:3.30.70.260 453 526 6.0E-18 T 14-10-2018 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 SUPERFAMILY SSF143548 318 447 7.32E-39 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 SUPERFAMILY SSF52283 15 127 3.78E-38 T 14-10-2018 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 Pfam PF01842 ACT domain 453 515 2.3E-9 T 14-10-2018 IPR002912 ACT domain HL41_04940 d02c6b35704e5b894a2fd8744218dd14 526 Gene3D G3DSA:3.30.1330.90 319 452 7.1E-42 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 5.5E-37 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 5.5E-37 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 86 104 5.5E-37 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 69 84 5.5E-37 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 PIRSF PIRSF006641 1 367 1.7E-154 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 Gene3D G3DSA:1.10.150.300 112 201 1.1E-148 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 Pfam PF06071 Protein of unknown function (DUF933) 283 366 2.7E-37 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 SUPERFAMILY SSF52540 1 305 4.59E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 Pfam PF01926 50S ribosome-binding GTPase 2 121 2.7E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 SUPERFAMILY SSF81271 283 364 1.24E-33 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 Gene3D G3DSA:3.40.50.300 1 282 1.1E-148 T 14-10-2018 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 Gene3D G3DSA:3.10.20.30 47 365 1.1E-148 T 14-10-2018 IPR012675 Beta-grasp domain superfamily HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 1 367 43.262 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 HL41_06730 16b8f127fccdc8d3caeabf6d7b70163b 367 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 2 367 5.6E-145 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 21 41 4.6E-9 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 4.6E-9 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 Hamap MF_00367 GTPase Era [era]. 16 306 36.642 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 SUPERFAMILY SSF52540 21 216 1.9E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 19 177 1.7E-34 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 TIGRFAM TIGR00436 era: GTP-binding protein Era 19 289 5.8E-93 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 Gene3D G3DSA:3.30.300.20 194 306 4.1E-41 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 SUPERFAMILY SSF54814 191 304 3.6E-37 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 Pfam PF01926 50S ribosome-binding GTPase 21 134 3.1E-28 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 Gene3D G3DSA:3.40.50.300 12 191 1.7E-53 T 14-10-2018 HL41_02360 6e71c5eb17968633cb3f5219e2ae1662 310 Pfam PF07650 KH domain 217 295 2.0E-19 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_09090 7bd635a9eb691b1a82726772e8f9eec0 333 Pfam PF01032 FecCD transport family 15 323 7.5E-93 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 HL41_09090 7bd635a9eb691b1a82726772e8f9eec0 333 SUPERFAMILY SSF81345 6 324 7.45E-82 T 14-10-2018 IPR037294 ABC transporter, BtuC-like HL41_09090 7bd635a9eb691b1a82726772e8f9eec0 333 Gene3D G3DSA:1.10.3470.10 3 329 3.8E-101 T 14-10-2018 IPR037294 ABC transporter, BtuC-like HL41_08565 2afbacfe47496345ab278854504df27a 433 PIRSF PIRSF006444 1 433 2.7E-176 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 HL41_08565 2afbacfe47496345ab278854504df27a 433 Pfam PF14535 AMP-binding enzyme C-terminal domain 338 431 4.5E-28 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal HL41_08565 2afbacfe47496345ab278854504df27a 433 SUPERFAMILY SSF56801 39 374 2.35E-59 T 14-10-2018 HL41_08565 2afbacfe47496345ab278854504df27a 433 Gene3D G3DSA:3.30.300.30 330 433 7.0E-31 T 14-10-2018 HL41_08565 2afbacfe47496345ab278854504df27a 433 Pfam PF00501 AMP-binding enzyme 32 289 2.1E-18 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HL41_08565 2afbacfe47496345ab278854504df27a 433 ProSitePatterns PS00455 Putative AMP-binding domain signature. 90 101 - T 14-10-2018 IPR020845 AMP-binding, conserved site HL41_08565 2afbacfe47496345ab278854504df27a 433 Gene3D G3DSA:3.40.50.12780 2 329 2.4E-125 T 14-10-2018 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 Gene3D G3DSA:1.10.10.60 409 452 2.1E-15 T 14-10-2018 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 157 170 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 Pfam PF02954 Bacterial regulatory protein, Fis family 411 450 2.1E-15 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 Gene3D G3DSA:1.10.8.60 305 386 1.0E-25 T 14-10-2018 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 Pfam PF13426 PAS domain 21 116 5.1E-9 T 14-10-2018 IPR000014 PAS domain HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 346 355 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 SUPERFAMILY SSF46689 347 452 1.43E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 SMART SM00091 10 76 6.8E-4 T 14-10-2018 IPR000014 PAS domain HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 SUPERFAMILY SSF55785 6 110 3.66E-11 T 14-10-2018 IPR035965 PAS domain superfamily HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 Gene3D G3DSA:3.40.50.300 128 304 1.1E-63 T 14-10-2018 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 416 433 3.8E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 433 453 3.8E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 SMART SM00382 153 297 6.2E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 SUPERFAMILY SSF52540 133 377 1.28E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 119 4.5E-12 T 14-10-2018 IPR000014 PAS domain HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 Pfam PF00158 Sigma-54 interaction domain 133 299 3.4E-67 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_08225 e7465ec9aeac0878910e4bd76ae395c3 453 Gene3D G3DSA:3.30.450.20 2 114 2.6E-13 T 14-10-2018 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 SMART SM00028 89 122 4.4E-10 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 SMART SM00028 55 88 1.6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 SMART SM00028 21 54 1.4E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 SMART SM00028 157 190 2.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 SMART SM00028 123 156 92.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 Gene3D G3DSA:1.25.40.10 3 204 1.1E-48 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 SUPERFAMILY SSF48452 18 186 7.36E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 Pfam PF13432 Tetratricopeptide repeat 26 74 2.6E-8 T 14-10-2018 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 Pfam PF14559 Tetratricopeptide repeat 135 183 1.2E-6 T 14-10-2018 HL41_05730 13ee13c5d573b843c71931b3f5651e67 204 Pfam PF00515 Tetratricopeptide repeat 89 122 1.2E-12 T 14-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HL41_00310 cb81c33ec47ea88e7753329b48dcd99c 230 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 1 222 38.108 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HL41_00310 cb81c33ec47ea88e7753329b48dcd99c 230 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 221 4.3E-62 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HL41_00310 cb81c33ec47ea88e7753329b48dcd99c 230 SUPERFAMILY SSF53448 1 222 3.9E-56 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_00310 cb81c33ec47ea88e7753329b48dcd99c 230 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 221 5.6E-67 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HL41_00310 cb81c33ec47ea88e7753329b48dcd99c 230 Gene3D G3DSA:3.90.550.10 2 226 1.1E-71 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 251 369 1.5E-26 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 370 1.3E-79 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 PIRSF PIRSF000804 1 371 1.6E-92 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 SUPERFAMILY SSF55979 1 123 1.28E-16 T 14-10-2018 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 Gene3D G3DSA:3.70.10.10 141 369 1.5E-96 T 14-10-2018 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 SUPERFAMILY SSF55979 129 249 7.3E-17 T 14-10-2018 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 132 248 6.7E-18 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 123 1.5E-14 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 SUPERFAMILY SSF55979 252 369 9.99E-30 T 14-10-2018 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 Gene3D G3DSA:3.10.150.10 1 247 1.5E-96 T 14-10-2018 HL41_02010 a3dcf07a0f13a152f5a9b3bac19d4fcb 371 SMART SM00480 17 367 4.4E-76 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 HL41_05030 5a5a44766ca81a9c18f52d93868b495e 120 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 78 113 5.6E-14 T 14-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 HL41_05030 5a5a44766ca81a9c18f52d93868b495e 120 SUPERFAMILY SSF109635 1 79 4.45E-23 T 14-10-2018 IPR037187 DksA, N-terminal domain superfamily HL41_05030 5a5a44766ca81a9c18f52d93868b495e 120 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 83 107 - T 14-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site HL41_05030 5a5a44766ca81a9c18f52d93868b495e 120 Gene3D G3DSA:1.20.120.910 1 119 5.0E-39 T 14-10-2018 HL41_05030 5a5a44766ca81a9c18f52d93868b495e 120 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 1 109 2.1E-38 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 HL41_05030 5a5a44766ca81a9c18f52d93868b495e 120 PRINTS PR00618 DksA/TraR zinc finger signature 95 107 9.1E-5 T 14-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria HL41_05030 5a5a44766ca81a9c18f52d93868b495e 120 PRINTS PR00618 DksA/TraR zinc finger signature 83 94 9.1E-5 T 14-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria HL41_05030 5a5a44766ca81a9c18f52d93868b495e 120 SUPERFAMILY SSF57716 80 117 1.76E-11 T 14-10-2018 HL41_02400 5a7bb906d1c715dc3d6bfc1eeeb8e1f1 441 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 431 4.1E-175 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 HL41_02400 5a7bb906d1c715dc3d6bfc1eeeb8e1f1 441 PIRSF PIRSF006446 1 439 1.8E-170 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 HL41_04275 67599c315b11ea052f4fbf53ee525a4c 408 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 290 309 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 HL41_04275 67599c315b11ea052f4fbf53ee525a4c 408 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 8 403 2.8E-195 T 14-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 HL41_04275 67599c315b11ea052f4fbf53ee525a4c 408 Gene3D G3DSA:3.40.718.10 1 404 8.1E-172 T 14-10-2018 HL41_04275 67599c315b11ea052f4fbf53ee525a4c 408 SUPERFAMILY SSF53659 9 403 3.26E-140 T 14-10-2018 HL41_04275 67599c315b11ea052f4fbf53ee525a4c 408 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 20 399 1.8E-114 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HL41_04275 67599c315b11ea052f4fbf53ee525a4c 408 SMART SM01329 19 399 5.5E-186 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HL41_07965 df2a13c08849238a2af08570148face0 267 Pfam PF00290 Tryptophan synthase alpha chain 14 264 7.7E-77 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HL41_07965 df2a13c08849238a2af08570148face0 267 SUPERFAMILY SSF51366 7 263 5.27E-76 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HL41_07965 df2a13c08849238a2af08570148face0 267 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 267 32.238 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HL41_07965 df2a13c08849238a2af08570148face0 267 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 13 265 4.3E-73 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HL41_07965 df2a13c08849238a2af08570148face0 267 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HL41_07965 df2a13c08849238a2af08570148face0 267 Gene3D G3DSA:3.20.20.70 3 267 1.7E-89 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_07755 56ab5f30f54884279ffcdb3307f23296 330 Gene3D G3DSA:3.100.10.20 1 81 3.3E-33 T 14-10-2018 HL41_07755 56ab5f30f54884279ffcdb3307f23296 330 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 4 325 2.4E-106 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HL41_07755 56ab5f30f54884279ffcdb3307f23296 330 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 3 330 1.1E-145 T 14-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 HL41_07755 56ab5f30f54884279ffcdb3307f23296 330 Pfam PF01867 CRISPR associated protein Cas1 5 285 3.3E-97 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HL41_07755 56ab5f30f54884279ffcdb3307f23296 330 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 315 27.441 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HL41_07755 56ab5f30f54884279ffcdb3307f23296 330 Gene3D G3DSA:1.20.120.920 82 330 3.7E-73 T 14-10-2018 HL41_00180 50eef506ad46e863e4d9a35f67eff3cb 125 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 3 124 7.4E-18 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 HL41_00180 50eef506ad46e863e4d9a35f67eff3cb 125 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 4 123 2.4E-17 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 HL41_00180 50eef506ad46e863e4d9a35f67eff3cb 125 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 125 20.147 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 HL41_00180 50eef506ad46e863e4d9a35f67eff3cb 125 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 119 9.1E-16 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 HL41_00180 50eef506ad46e863e4d9a35f67eff3cb 125 Gene3D G3DSA:3.90.470.20 1 125 1.4E-33 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 HL41_00180 50eef506ad46e863e4d9a35f67eff3cb 125 SUPERFAMILY SSF56214 4 123 4.32E-22 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 HL41_00180 50eef506ad46e863e4d9a35f67eff3cb 125 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 123 6.0E-14 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 19 316 2.4E-129 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 SMART SM00840 357 425 0.0027 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 Pfam PF09190 DALR domain 357 423 1.2E-7 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 Gene3D G3DSA:1.20.120.640 310 488 2.7E-31 T 14-10-2018 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 6 486 4.5E-164 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 6 489 37.758 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 Gene3D G3DSA:3.40.50.620 1 308 1.6E-135 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 194 212 4.9E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 65 74 4.9E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 29 40 4.9E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 225 246 4.9E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 SUPERFAMILY SSF52374 6 316 5.12E-101 T 14-10-2018 HL41_05600 3a3e99d12c9563e940830a85c0d05930 489 SUPERFAMILY SSF47323 346 488 3.4E-27 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_00025 5343df8941a46efca81e0ebf11123166 318 SUPERFAMILY SSF56770 2 267 3.14E-44 T 14-10-2018 HL41_00025 5343df8941a46efca81e0ebf11123166 318 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 181 3.3E-24 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_09215 5343df8941a46efca81e0ebf11123166 318 SUPERFAMILY SSF56770 2 267 3.14E-44 T 14-10-2018 HL41_09215 5343df8941a46efca81e0ebf11123166 318 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 181 3.3E-24 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 Pfam PF13522 Glutamine amidotransferase domain 70 183 1.9E-19 T 14-10-2018 HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 Gene3D G3DSA:3.40.50.10490 250 613 2.2E-143 T 14-10-2018 HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 SUPERFAMILY SSF53697 248 614 3.43E-105 T 14-10-2018 HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 SUPERFAMILY SSF56235 2 239 2.92E-71 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 Gene3D G3DSA:3.40.50.10490 449 599 2.2E-143 T 14-10-2018 HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 Pfam PF01380 SIS domain 298 419 4.9E-31 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 Pfam PF01380 SIS domain 466 595 2.5E-16 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 614 3.7E-247 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 614 40.7 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 HL41_03610 d8e10ca1eb5f3b9dfa8c01c2f4b636a6 614 Gene3D G3DSA:3.60.20.10 2 243 7.6E-74 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HL41_02205 5e1508fd194b578ad5e2183e10d4f45b 230 SUPERFAMILY SSF52540 2 122 8.04E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02205 5e1508fd194b578ad5e2183e10d4f45b 230 Gene3D G3DSA:3.40.50.300 1 185 3.0E-30 T 14-10-2018 HL41_02205 5e1508fd194b578ad5e2183e10d4f45b 230 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 5 141 3.8E-21 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 HL41_01990 71e03444052e42ba39350ef19412265f 332 Pfam PF04143 Sulphur transport 28 109 1.7E-10 T 14-10-2018 IPR007272 Sulphur transport domain HL41_01990 71e03444052e42ba39350ef19412265f 332 Pfam PF04143 Sulphur transport 169 317 6.6E-18 T 14-10-2018 IPR007272 Sulphur transport domain HL41_06270 cf5371f67ad8325ecbbc7749f6d5540a 470 Gene3D G3DSA:2.60.120.10 347 456 3.6E-17 T 14-10-2018 IPR014710 RmlC-like jelly roll fold HL41_06270 cf5371f67ad8325ecbbc7749f6d5540a 470 Pfam PF01050 Mannose-6-phosphate isomerase 314 464 1.7E-65 T 14-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 HL41_06270 cf5371f67ad8325ecbbc7749f6d5540a 470 Gene3D G3DSA:3.90.550.10 1 346 1.2E-117 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_06270 cf5371f67ad8325ecbbc7749f6d5540a 470 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 468 5.0E-172 T 14-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 HL41_06270 cf5371f67ad8325ecbbc7749f6d5540a 470 SUPERFAMILY SSF53448 1 278 2.82E-69 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_06270 cf5371f67ad8325ecbbc7749f6d5540a 470 Pfam PF00483 Nucleotidyl transferase 2 284 1.1E-59 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HL41_06270 cf5371f67ad8325ecbbc7749f6d5540a 470 SUPERFAMILY SSF51182 194 468 1.41E-70 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily HL41_02500 5c9e3ad80f33cf84fa5545e4bfbcb58a 216 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_02500 5c9e3ad80f33cf84fa5545e4bfbcb58a 216 SMART SM00382 29 211 2.0E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_02500 5c9e3ad80f33cf84fa5545e4bfbcb58a 216 Gene3D G3DSA:3.40.50.300 2 215 3.4E-59 T 14-10-2018 HL41_02500 5c9e3ad80f33cf84fa5545e4bfbcb58a 216 SUPERFAMILY SSF52540 5 212 2.95E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02500 5c9e3ad80f33cf84fa5545e4bfbcb58a 216 Pfam PF00005 ABC transporter 20 167 8.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_08695 efe82e4de9c321fd67a96510eadc17d2 101 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 95 9.4E-24 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like HL41_08695 efe82e4de9c321fd67a96510eadc17d2 101 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 100 18.169 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 HL41_06460 fe8677f0a593c9d43bfe02ef6196a90f 561 Gene3D G3DSA:3.10.310.30 328 449 1.1E-23 T 14-10-2018 HL41_06460 fe8677f0a593c9d43bfe02ef6196a90f 561 Pfam PF01368 DHH family 83 206 1.3E-8 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HL41_06460 fe8677f0a593c9d43bfe02ef6196a90f 561 Pfam PF02272 DHHA1 domain 325 443 8.8E-13 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HL41_06460 fe8677f0a593c9d43bfe02ef6196a90f 561 SUPERFAMILY SSF64182 58 447 5.1E-89 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily HL41_06460 fe8677f0a593c9d43bfe02ef6196a90f 561 Gene3D G3DSA:3.90.1640.30 57 327 1.8E-72 T 14-10-2018 HL41_06460 fe8677f0a593c9d43bfe02ef6196a90f 561 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 545 8.2E-131 T 14-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 HL41_08330 462dcafd28f4c45753fc4ceda2a027a0 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 302 1.5E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HL41_08330 462dcafd28f4c45753fc4ceda2a027a0 313 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 14 306 1.2E-91 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 HL41_08330 462dcafd28f4c45753fc4ceda2a027a0 313 SUPERFAMILY SSF161098 21 300 1.83E-33 T 14-10-2018 IPR035906 MetI-like superfamily HL41_08330 462dcafd28f4c45753fc4ceda2a027a0 313 Gene3D G3DSA:1.10.3720.10 61 311 1.6E-29 T 14-10-2018 IPR035906 MetI-like superfamily HL41_08310 3a49422dc8b5a48b72a6be8da8d0e572 254 Pfam PF01975 Survival protein SurE 4 185 7.9E-57 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 HL41_08310 3a49422dc8b5a48b72a6be8da8d0e572 254 SUPERFAMILY SSF64167 1 250 4.32E-79 T 14-10-2018 HL41_08310 3a49422dc8b5a48b72a6be8da8d0e572 254 Gene3D G3DSA:3.40.1210.10 1 252 4.6E-84 T 14-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 HL41_08310 3a49422dc8b5a48b72a6be8da8d0e572 254 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 252 35.0 T 14-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 HL41_08310 3a49422dc8b5a48b72a6be8da8d0e572 254 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 235 2.9E-66 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 HL41_08885 768e45a2186b777991f1be0206979dbf 266 PIRSF PIRSF015601 25 265 2.0E-50 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 HL41_08885 768e45a2186b777991f1be0206979dbf 266 Gene3D G3DSA:3.40.1280.10 24 265 5.2E-55 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HL41_08885 768e45a2186b777991f1be0206979dbf 266 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 37 260 4.2E-39 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 HL41_08885 768e45a2186b777991f1be0206979dbf 266 SUPERFAMILY SSF88697 28 82 1.04E-9 T 14-10-2018 IPR015947 PUA-like superfamily HL41_08885 768e45a2186b777991f1be0206979dbf 266 SUPERFAMILY SSF75217 100 260 7.85E-34 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases HL41_08885 768e45a2186b777991f1be0206979dbf 266 Pfam PF04452 RNA methyltransferase 38 259 6.0E-49 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 HL41_00345 17932411a8e22bb7c64afa9691533177 298 SUPERFAMILY SSF56349 3 289 5.0E-58 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HL41_00345 17932411a8e22bb7c64afa9691533177 298 Gene3D G3DSA:1.10.443.10 110 288 1.1E-58 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 HL41_00345 17932411a8e22bb7c64afa9691533177 298 Gene3D G3DSA:1.10.150.130 2 96 1.1E-25 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal HL41_00345 17932411a8e22bb7c64afa9691533177 298 Pfam PF00589 Phage integrase family 112 281 6.1E-46 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HL41_00345 17932411a8e22bb7c64afa9691533177 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 295 52.826 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD HL41_00345 17932411a8e22bb7c64afa9691533177 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 86 8.8E-22 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 SUPERFAMILY SSF88659 163 243 8.78E-22 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 PRINTS PR00046 Major sigma-70 factor signature 195 207 1.2E-10 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 PRINTS PR00046 Major sigma-70 factor signature 212 227 1.2E-10 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 PRINTS PR00046 Major sigma-70 factor signature 46 59 1.2E-10 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 PRINTS PR00046 Major sigma-70 factor signature 227 238 1.2E-10 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 PIRSF PIRSF000770 14 80 3.3E-9 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 PIRSF PIRSF000770 76 246 1.2E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 Gene3D G3DSA:1.20.140.160 90 245 1.5E-44 T 14-10-2018 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 Pfam PF04539 Sigma-70 region 3 99 153 4.6E-8 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 20 242 4.5E-73 T 14-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 SUPERFAMILY SSF88946 16 90 1.29E-19 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 Pfam PF04545 Sigma-70, region 4 191 239 6.3E-17 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 241 1.8E-34 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 Gene3D G3DSA:1.10.1740.10 5 89 3.5E-24 T 14-10-2018 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 Pfam PF04542 Sigma-70 region 2 20 88 7.8E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HL41_02590 de8fe6a27aac4d72b1c32992dd70082e 249 SUPERFAMILY SSF88659 92 151 3.66E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HL41_02130 57a5f1c1c5ec7283d74d820088399c95 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 231 246 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 HL41_02130 57a5f1c1c5ec7283d74d820088399c95 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 19 101 1.5E-32 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 HL41_02130 57a5f1c1c5ec7283d74d820088399c95 444 Pfam PF00120 Glutamine synthetase, catalytic domain 108 440 7.3E-127 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HL41_02130 57a5f1c1c5ec7283d74d820088399c95 444 SMART SM01230 107 354 5.7E-130 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HL41_02130 57a5f1c1c5ec7283d74d820088399c95 444 SUPERFAMILY SSF54368 9 106 5.49E-33 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HL41_02130 57a5f1c1c5ec7283d74d820088399c95 444 Gene3D G3DSA:3.10.20.70 6 109 7.9E-42 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HL41_02130 57a5f1c1c5ec7283d74d820088399c95 444 Gene3D G3DSA:3.30.590.10 110 443 2.8E-123 T 14-10-2018 HL41_02130 57a5f1c1c5ec7283d74d820088399c95 444 SUPERFAMILY SSF55931 108 442 9.81E-121 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 HL41_01260 de3364170c094bd19aff149dd02c1205 424 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 6 422 50.285 T 14-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 Pfam PF00330 Aconitase family (aconitate hydratase) 10 414 1.1E-92 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 Gene3D G3DSA:3.30.499.20 7 273 1.4E-100 T 14-10-2018 HL41_01260 de3364170c094bd19aff149dd02c1205 424 TIGRFAM TIGR02083 LEU2: 3-isopropylmalate dehydratase, large subunit 6 422 2.1E-213 T 14-10-2018 IPR011823 3-isopropylmalate dehydratase, large subunit, bacteria GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 SUPERFAMILY SSF53732 4 422 1.19E-141 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 6 420 3.1E-163 T 14-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 ProSitePatterns PS00450 Aconitase family signature 1. 295 311 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 Gene3D G3DSA:3.30.499.10 276 423 1.7E-55 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 7 420 5.6E-181 T 14-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 ProSitePatterns PS01244 Aconitase family signature 2. 355 368 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 PRINTS PR00415 Aconitase family signature 131 146 4.0E-19 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 PRINTS PR00415 Aconitase family signature 117 130 4.0E-19 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 PRINTS PR00415 Aconitase family signature 355 368 4.0E-19 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 PRINTS PR00415 Aconitase family signature 193 206 4.0E-19 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_01260 de3364170c094bd19aff149dd02c1205 424 PRINTS PR00415 Aconitase family signature 207 220 4.0E-19 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_07105 f3f7a15dd831e51d88dc442429beea3c 172 TIGRFAM TIGR01611 tail_tube: phage major tail tube protein 4 172 1.9E-41 T 14-10-2018 IPR006498 Tail tube protein HL41_07105 f3f7a15dd831e51d88dc442429beea3c 172 Pfam PF04985 Phage tail tube protein FII 6 171 1.6E-47 T 14-10-2018 IPR006498 Tail tube protein HL41_07505 10de744b78d3d1fa834afa706ccd9783 751 SUPERFAMILY SSF51726 5 366 8.76E-71 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HL41_07505 10de744b78d3d1fa834afa706ccd9783 751 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 311 6.4E-95 T 14-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HL41_07505 10de744b78d3d1fa834afa706ccd9783 751 PIRSF PIRSF000382 1 751 1.9E-296 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HL41_07505 10de744b78d3d1fa834afa706ccd9783 751 Gene3D G3DSA:3.20.20.210 7 516 1.1E-302 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HL41_07505 10de744b78d3d1fa834afa706ccd9783 751 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 750 1.9E-303 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HL41_07505 10de744b78d3d1fa834afa706ccd9783 751 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 423 745 9.9E-151 T 14-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HL41_07505 10de744b78d3d1fa834afa706ccd9783 751 SUPERFAMILY SSF51726 388 750 1.03E-117 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HL41_07505 10de744b78d3d1fa834afa706ccd9783 751 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 1 750 32.709 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HL41_07505 10de744b78d3d1fa834afa706ccd9783 751 Gene3D G3DSA:3.20.20.210 383 748 1.1E-302 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HL41_00735 f786d1028e65a293cc6942247c3f2f68 199 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 185 29.502 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 HL41_00735 f786d1028e65a293cc6942247c3f2f68 199 Pfam PF01386 Ribosomal L25p family 6 96 6.0E-27 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 HL41_00735 f786d1028e65a293cc6942247c3f2f68 199 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 99 2.0E-11 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 HL41_00735 f786d1028e65a293cc6942247c3f2f68 199 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 184 8.0E-53 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 HL41_00735 f786d1028e65a293cc6942247c3f2f68 199 Gene3D G3DSA:2.40.240.10 4 98 1.2E-26 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HL41_00735 f786d1028e65a293cc6942247c3f2f68 199 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 105 185 3.5E-29 T 14-10-2018 IPR020057 Ribosomal protein L25, beta domain HL41_00735 f786d1028e65a293cc6942247c3f2f68 199 Gene3D G3DSA:2.170.120.20 102 192 2.2E-31 T 14-10-2018 IPR037121 Ribosomal protein L25, C-terminal HL41_00735 f786d1028e65a293cc6942247c3f2f68 199 SUPERFAMILY SSF50715 10 185 1.67E-57 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HL41_01010 45d8384b5dfb842758d7f0d64a2e07e8 600 Pfam PF00682 HMGL-like 49 323 4.6E-31 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HL41_01010 45d8384b5dfb842758d7f0d64a2e07e8 600 Gene3D G3DSA:3.20.20.70 42 371 1.3E-72 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_01010 45d8384b5dfb842758d7f0d64a2e07e8 600 Gene3D G3DSA:3.30.450.20 480 585 1.3E-18 T 14-10-2018 HL41_01010 45d8384b5dfb842758d7f0d64a2e07e8 600 SUPERFAMILY SSF103190 482 595 7.85E-11 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily HL41_01010 45d8384b5dfb842758d7f0d64a2e07e8 600 Pfam PF02743 Cache domain 477 591 7.0E-14 T 14-10-2018 IPR033479 Double Cache domain 1 HL41_01010 45d8384b5dfb842758d7f0d64a2e07e8 600 SUPERFAMILY SSF51569 45 342 2.38E-55 T 14-10-2018 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 Gene3D G3DSA:1.10.560.10 8 520 5.2E-248 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 SUPERFAMILY SSF52029 184 376 8.52E-89 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 SUPERFAMILY SSF48592 7 520 3.89E-81 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 PRINTS PR00298 60kDa chaperonin signature 398 419 2.5E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 PRINTS PR00298 60kDa chaperonin signature 83 110 2.5E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 PRINTS PR00298 60kDa chaperonin signature 27 53 2.5E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 PRINTS PR00298 60kDa chaperonin signature 268 291 2.5E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 PRINTS PR00298 60kDa chaperonin signature 350 375 2.5E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 SUPERFAMILY SSF54849 137 204 2.75E-25 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 2.0E-266 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 2.4E-106 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 Hamap MF_00600 60 kDa chaperonin [groL]. 2 539 42.328 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 Gene3D G3DSA:3.50.7.10 192 372 5.2E-248 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HL41_04625 1d4008a2b7d4265ac07104fa09c73a9b 539 Gene3D G3DSA:3.30.260.10 136 410 5.2E-248 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily HL41_08890 1ecc5a36101f9a74b6a08d699c7a35c2 775 Gene3D G3DSA:3.40.50.300 540 751 7.8E-19 T 14-10-2018 HL41_08890 1ecc5a36101f9a74b6a08d699c7a35c2 775 SUPERFAMILY SSF52540 8 737 3.38E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08890 1ecc5a36101f9a74b6a08d699c7a35c2 775 Gene3D G3DSA:3.40.50.300 445 536 1.6E-6 T 14-10-2018 HL41_08890 1ecc5a36101f9a74b6a08d699c7a35c2 775 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 332 4.6E-36 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 HL41_08890 1ecc5a36101f9a74b6a08d699c7a35c2 775 Pfam PF13361 UvrD-like helicase C-terminal domain 344 732 4.2E-25 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HL41_08890 1ecc5a36101f9a74b6a08d699c7a35c2 775 Gene3D G3DSA:3.40.50.300 2 171 2.3E-24 T 14-10-2018 HL41_08890 1ecc5a36101f9a74b6a08d699c7a35c2 775 Gene3D G3DSA:3.40.50.300 251 365 2.6E-23 T 14-10-2018 HL41_02355 34ac671510a86c548a7772601234fd03 117 Pfam PF06935 Protein of unknown function (DUF1284) 18 115 4.3E-20 T 14-10-2018 IPR009702 Protein of unknown function DUF1284 HL41_00505 55a31688501e99f1c50359da3a09f504 297 SMART SM00382 45 191 7.0E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_00505 55a31688501e99f1c50359da3a09f504 297 SUPERFAMILY SSF52540 30 254 1.52E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00505 55a31688501e99f1c50359da3a09f504 297 Pfam PF07728 AAA domain (dynein-related subfamily) 51 180 2.1E-19 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 HL41_00505 55a31688501e99f1c50359da3a09f504 297 Gene3D G3DSA:3.40.50.300 36 200 8.0E-27 T 14-10-2018 HL41_02225 a380945b91e27f244003189df94007f1 389 Gene3D G3DSA:3.40.50.920 250 386 9.2E-46 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HL41_02225 a380945b91e27f244003189df94007f1 389 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 233 3.9E-74 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HL41_02225 a380945b91e27f244003189df94007f1 389 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 259 363 2.8E-29 T 14-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HL41_02225 a380945b91e27f244003189df94007f1 389 SUPERFAMILY SSF52518 11 248 4.12E-70 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold HL41_02225 a380945b91e27f244003189df94007f1 389 SUPERFAMILY SSF52922 250 375 4.32E-37 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HL41_02225 a380945b91e27f244003189df94007f1 389 Gene3D G3DSA:3.40.50.970 3 248 4.4E-96 T 14-10-2018 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 6 469 2.9E-252 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 Gene3D G3DSA:2.40.10.170 5 83 3.7E-31 T 14-10-2018 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 SUPERFAMILY SSF50615 6 83 8.37E-28 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 81 8.9E-23 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 SUPERFAMILY SSF47917 354 469 1.46E-53 T 14-10-2018 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 SUPERFAMILY SSF52540 85 356 2.25E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 PIRSF PIRSF039072 1 472 3.6E-265 T 14-10-2018 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 Hamap MF_01347 ATP synthase subunit beta [atpB]. 4 469 57.263 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 351 1.2E-63 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 Gene3D G3DSA:1.10.1140.10 354 472 3.9E-59 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_01095 52d919c572dbcdd233e0cb8f2c66b137 472 Gene3D G3DSA:3.40.50.300 84 353 2.2E-112 T 14-10-2018 HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 274 288 5.8E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 5.8E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 SUPERFAMILY SSF47384 118 184 2.16E-7 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 Pfam PF00512 His Kinase A (phospho-acceptor) domain 127 184 1.0E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 Gene3D G3DSA:1.10.287.130 116 186 2.6E-7 T 14-10-2018 HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 236 341 2.1E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 SMART SM00387 236 343 2.2E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 SUPERFAMILY SSF55874 189 342 1.2E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 SMART SM00388 122 189 1.1E-4 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_08345 61986c152888bb11fbe9febc7be1ce48 343 Gene3D G3DSA:3.30.565.10 187 342 4.6E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_03575 cb9d6f8f53940a7d9fd7117bcf426649 145 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 15 141 6.3E-31 T 14-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 HL41_03575 cb9d6f8f53940a7d9fd7117bcf426649 145 Gene3D G3DSA:3.40.630.30 8 145 3.1E-34 T 14-10-2018 HL41_03575 cb9d6f8f53940a7d9fd7117bcf426649 145 Pfam PF00583 Acetyltransferase (GNAT) family 22 123 9.6E-16 T 14-10-2018 IPR000182 GNAT domain HL41_03575 cb9d6f8f53940a7d9fd7117bcf426649 145 SUPERFAMILY SSF55729 1 145 4.65E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase HL41_05150 9807b9d5993cbad6a8c7fb3ccf03e064 197 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 72 94 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HL41_05150 9807b9d5993cbad6a8c7fb3ccf03e064 197 Gene3D G3DSA:1.20.120.1760 11 197 1.7E-59 T 14-10-2018 HL41_05150 9807b9d5993cbad6a8c7fb3ccf03e064 197 Pfam PF01066 CDP-alcohol phosphatidyltransferase 31 94 1.4E-13 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HL41_00680 86a92ee25b791810ed103346c9b46fce 252 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 4 234 12.543 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_00680 86a92ee25b791810ed103346c9b46fce 252 Pfam PF00902 Sec-independent protein translocase protein (TatC) 24 216 1.9E-35 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_00680 86a92ee25b791810ed103346c9b46fce 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 148 176 2.9E-11 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_00680 86a92ee25b791810ed103346c9b46fce 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 97 123 2.9E-11 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 SUPERFAMILY SSF46689 342 439 8.96E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 341 350 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HL41_00525 520ac99e5260a6e848a69f84375abe85 449 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 152 165 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 SUPERFAMILY SSF52540 132 370 3.56E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00525 520ac99e5260a6e848a69f84375abe85 449 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 2.7E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 2.7E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 Pfam PF00158 Sigma-54 interaction domain 130 294 9.7E-69 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 214 229 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 Pfam PF02954 Bacterial regulatory protein, Fis family 399 439 6.5E-17 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 SMART SM00382 148 291 2.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_00525 520ac99e5260a6e848a69f84375abe85 449 SUPERFAMILY SSF52172 15 172 6.46E-10 T 14-10-2018 IPR011006 CheY-like superfamily HL41_00525 520ac99e5260a6e848a69f84375abe85 449 Gene3D G3DSA:1.10.8.60 299 365 1.1E-25 T 14-10-2018 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 Gene3D G3DSA:1.10.10.60 375 440 6.6E-15 T 14-10-2018 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 Gene3D G3DSA:3.40.50.2300 13 109 2.6E-6 T 14-10-2018 HL41_00525 520ac99e5260a6e848a69f84375abe85 449 Gene3D G3DSA:3.40.50.300 115 298 2.3E-69 T 14-10-2018 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 Pfam PF00119 ATP synthase A chain 42 242 4.8E-47 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 Gene3D G3DSA:1.20.120.220 99 249 1.0E-34 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 42 243 2.1E-35 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 PRINTS PR00123 ATP synthase A subunit signature 229 244 6.5E-14 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 PRINTS PR00123 ATP synthase A subunit signature 105 121 6.5E-14 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 PRINTS PR00123 ATP synthase A subunit signature 164 179 6.5E-14 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 PRINTS PR00123 ATP synthase A subunit signature 184 206 6.5E-14 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 249 13.93 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 SUPERFAMILY SSF81336 99 242 3.27E-29 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00080 a7a881a86f958440c7fd0d1416c78b39 250 ProSitePatterns PS00449 ATP synthase a subunit signature. 187 196 - T 14-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01940 fb84e114f16e468fef4a8777e860b558 196 Pfam PF02142 MGS-like domain 16 130 1.8E-28 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain HL41_01940 fb84e114f16e468fef4a8777e860b558 196 SMART SM00851 16 130 1.6E-53 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain HL41_01940 fb84e114f16e468fef4a8777e860b558 196 SUPERFAMILY SSF52335 4 193 8.77E-68 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HL41_01940 fb84e114f16e468fef4a8777e860b558 196 Gene3D G3DSA:3.40.50.1380 1 195 3.9E-89 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HL41_01940 fb84e114f16e468fef4a8777e860b558 196 Pfam PF01808 AICARFT/IMPCHase bienzyme 136 192 3.1E-17 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_04185 c7f6fd4713595cbde385a45bab40f805 355 Pfam PF02754 Cysteine-rich domain 141 221 3.9E-10 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_04185 c7f6fd4713595cbde385a45bab40f805 355 Pfam PF02754 Cysteine-rich domain 292 338 0.058 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_04185 c7f6fd4713595cbde385a45bab40f805 355 Gene3D G3DSA:3.30.70.20 4 77 2.6E-9 T 14-10-2018 HL41_04185 c7f6fd4713595cbde385a45bab40f805 355 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 55 66 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_04185 c7f6fd4713595cbde385a45bab40f805 355 Pfam PF13183 4Fe-4S dicluster domain 11 68 9.4E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_04185 c7f6fd4713595cbde385a45bab40f805 355 SUPERFAMILY SSF54862 7 79 6.28E-16 T 14-10-2018 HL41_04185 c7f6fd4713595cbde385a45bab40f805 355 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07870 d23603ab1e0dca1d131f4e11577f8353 463 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 172 201 6.7E-14 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_07870 d23603ab1e0dca1d131f4e11577f8353 463 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 143 170 6.7E-14 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_07870 d23603ab1e0dca1d131f4e11577f8353 463 SMART SM00283 45 292 1.0E-21 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_07870 d23603ab1e0dca1d131f4e11577f8353 463 SUPERFAMILY SSF58104 51 307 7.98E-41 T 14-10-2018 HL41_07870 d23603ab1e0dca1d131f4e11577f8353 463 Gene3D G3DSA:1.10.287.950 17 317 2.2E-42 T 14-10-2018 HL41_07870 d23603ab1e0dca1d131f4e11577f8353 463 Gene3D G3DSA:3.30.450.20 331 435 1.5E-21 T 14-10-2018 HL41_07870 d23603ab1e0dca1d131f4e11577f8353 463 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 117 272 1.4E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_07870 d23603ab1e0dca1d131f4e11577f8353 463 SUPERFAMILY SSF103190 306 442 1.36E-26 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily HL41_07870 d23603ab1e0dca1d131f4e11577f8353 463 Pfam PF02743 Cache domain 317 439 1.4E-14 T 14-10-2018 IPR033479 Double Cache domain 1 HL41_08540 d0630a3622b7bffe15cb439fbb073ae6 890 Gene3D G3DSA:1.10.760.10 345 430 2.8E-5 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HL41_08540 d0630a3622b7bffe15cb439fbb073ae6 890 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 17 230 5.1E-9 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 HL41_08540 d0630a3622b7bffe15cb439fbb073ae6 890 Gene3D G3DSA:1.10.3820.10 670 825 3.9E-6 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily HL41_08540 d0630a3622b7bffe15cb439fbb073ae6 890 SUPERFAMILY SSF48695 605 822 4.19E-16 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_08540 d0630a3622b7bffe15cb439fbb073ae6 890 SUPERFAMILY SSF46626 346 422 6.45E-7 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 HL41_00480 27d3706bcb95ceff54197e871d90ddd0 430 Pfam PF00202 Aminotransferase class-III 32 411 1.1E-79 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HL41_00480 27d3706bcb95ceff54197e871d90ddd0 430 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HL41_00480 27d3706bcb95ceff54197e871d90ddd0 430 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 427 103.833 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 HL41_00480 27d3706bcb95ceff54197e871d90ddd0 430 Gene3D G3DSA:3.40.640.10 71 319 6.3E-180 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_00480 27d3706bcb95ceff54197e871d90ddd0 430 Gene3D G3DSA:3.90.1150.10 10 419 6.3E-180 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_00480 27d3706bcb95ceff54197e871d90ddd0 430 SUPERFAMILY SSF53383 3 427 2.62E-134 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_00480 27d3706bcb95ceff54197e871d90ddd0 430 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 7 426 9.3E-198 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 HL41_01045 effe58d3e4ea281f7fe444bb58525582 463 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 100 114 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 HL41_01045 effe58d3e4ea281f7fe444bb58525582 463 TIGRFAM TIGR00260 thrC: threonine synthase 66 430 6.7E-91 T 14-10-2018 IPR004450 Threonine synthase-like HL41_01045 effe58d3e4ea281f7fe444bb58525582 463 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 88 344 1.1E-11 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HL41_01045 effe58d3e4ea281f7fe444bb58525582 463 Pfam PF14821 Threonine synthase N terminus 2 79 1.3E-28 T 14-10-2018 IPR029144 Threonine synthase, N-terminal HL41_01045 effe58d3e4ea281f7fe444bb58525582 463 Gene3D G3DSA:3.40.50.1100 106 442 7.1E-148 T 14-10-2018 HL41_01045 effe58d3e4ea281f7fe444bb58525582 463 SUPERFAMILY SSF53686 1 460 6.42E-158 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HL41_01045 effe58d3e4ea281f7fe444bb58525582 463 Gene3D G3DSA:3.40.50.1100 95 430 7.1E-148 T 14-10-2018 HL41_01045 effe58d3e4ea281f7fe444bb58525582 463 Gene3D G3DSA:3.90.1380.10 1 85 5.6E-29 T 14-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily HL41_04105 91fc913f0cace66d8542a5dad5d0896a 291 Pfam PF02195 ParB-like nuclease domain 34 123 9.7E-26 T 14-10-2018 IPR003115 ParB/Sulfiredoxin HL41_04105 91fc913f0cace66d8542a5dad5d0896a 291 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 30 209 8.4E-57 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 HL41_04105 91fc913f0cace66d8542a5dad5d0896a 291 Gene3D G3DSA:3.90.1530.30 46 110 1.9E-23 T 14-10-2018 HL41_04105 91fc913f0cace66d8542a5dad5d0896a 291 Gene3D G3DSA:1.10.10.2830 111 225 9.1E-40 T 14-10-2018 HL41_04105 91fc913f0cace66d8542a5dad5d0896a 291 SUPERFAMILY SSF110849 32 126 1.86E-26 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily HL41_04105 91fc913f0cace66d8542a5dad5d0896a 291 SUPERFAMILY SSF109709 116 225 5.49E-37 T 14-10-2018 HL41_04105 91fc913f0cace66d8542a5dad5d0896a 291 SMART SM00470 33 124 8.0E-31 T 14-10-2018 IPR003115 ParB/Sulfiredoxin HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 Gene3D G3DSA:2.40.40.20 552 695 1.0E-42 T 14-10-2018 HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 Gene3D G3DSA:2.20.25.90 1 61 6.6E-16 T 14-10-2018 HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 Pfam PF01568 Molydopterin dinucleotide binding domain 570 658 1.2E-16 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 SUPERFAMILY SSF50692 531 679 1.33E-27 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 Gene3D G3DSA:3.30.2070.10 437 521 1.5E-123 T 14-10-2018 HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 SMART SM00926 2 56 3.7E-13 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 SUPERFAMILY SSF53706 3 576 4.19E-135 T 14-10-2018 HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 Gene3D G3DSA:3.40.228.10 135 547 1.5E-123 T 14-10-2018 HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 55 5.6E-11 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 Pfam PF00384 Molybdopterin oxidoreductase 62 480 3.4E-55 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08650 cc714a9cfbdc20ab79573f597eb43abd 695 Gene3D G3DSA:3.40.50.740 70 484 1.5E-123 T 14-10-2018 HL41_04760 bdfae3dbe902628d4b5bd8b276e53751 400 Pfam PF01875 Memo-like protein 118 394 6.1E-37 T 14-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 HL41_04760 bdfae3dbe902628d4b5bd8b276e53751 400 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 116 371 3.8E-20 T 14-10-2018 HL41_04760 bdfae3dbe902628d4b5bd8b276e53751 400 Gene3D G3DSA:3.40.830.10 115 398 9.0E-39 T 14-10-2018 HL41_03460 db9fe0303ccaf6633b2190ba94235778 156 Gene3D G3DSA:3.40.140.10 1 156 3.2E-59 T 14-10-2018 HL41_03460 db9fe0303ccaf6633b2190ba94235778 156 SUPERFAMILY SSF53927 3 155 7.19E-52 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 HL41_03460 db9fe0303ccaf6633b2190ba94235778 156 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 93 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HL41_03460 db9fe0303ccaf6633b2190ba94235778 156 Pfam PF14437 MafB19-like deaminase 9 149 5.8E-30 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 HL41_03460 db9fe0303ccaf6633b2190ba94235778 156 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 10 152 45.046 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 HL41_08895 5fdde7fb973ee6f4c2e88c2d0e7894be 212 Gene3D G3DSA:3.40.50.1000 8 180 1.5E-32 T 14-10-2018 IPR023214 HAD superfamily HL41_08895 5fdde7fb973ee6f4c2e88c2d0e7894be 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 179 2.7E-19 T 14-10-2018 HL41_08895 5fdde7fb973ee6f4c2e88c2d0e7894be 212 Gene3D G3DSA:1.10.150.240 18 86 1.5E-32 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 HL41_08895 5fdde7fb973ee6f4c2e88c2d0e7894be 212 SUPERFAMILY SSF56784 4 202 3.41E-37 T 14-10-2018 IPR036412 HAD-like superfamily HL41_00455 4d5898aed122ec6f1328230a929cb432 442 SUPERFAMILY SSF52540 42 353 5.71E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00455 4d5898aed122ec6f1328230a929cb432 442 Pfam PF02978 Signal peptide binding domain 326 421 3.4E-32 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 Gene3D G3DSA:1.20.120.140 5 305 1.0E-127 T 14-10-2018 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.4E-19 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 440 34.749 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 Gene3D G3DSA:3.40.50.300 90 284 1.0E-127 T 14-10-2018 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 424 4.0E-182 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 Gene3D G3DSA:1.10.260.30 326 440 8.5E-42 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 SMART SM00963 1 86 1.8E-28 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 SMART SM00962 100 295 2.0E-115 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 SMART SM00382 99 276 2.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_00455 4d5898aed122ec6f1328230a929cb432 442 SUPERFAMILY SSF47446 326 427 1.08E-35 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 HL41_00455 4d5898aed122ec6f1328230a929cb432 442 Pfam PF00448 SRP54-type protein, GTPase domain 101 295 1.2E-77 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_01590 392083ae462e6baaa6e66697cafba09b 203 SMART SM01207 9 190 1.5E-80 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HL41_01590 392083ae462e6baaa6e66697cafba09b 203 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 195 2.1E-51 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HL41_01590 392083ae462e6baaa6e66697cafba09b 203 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 189 1.6E-51 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HL41_01590 392083ae462e6baaa6e66697cafba09b 203 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 6 198 19.433 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HL41_04690 51f0ba61bb578a127716805d66b2cb76 288 Gene3D G3DSA:3.90.550.10 1 250 2.1E-65 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_04690 51f0ba61bb578a127716805d66b2cb76 288 Pfam PF00535 Glycosyl transferase family 2 7 129 1.2E-33 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HL41_04690 51f0ba61bb578a127716805d66b2cb76 288 SUPERFAMILY SSF53448 4 201 1.48E-62 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Gene3D G3DSA:1.20.1640.10 370 551 2.8E-9 T 14-10-2018 HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 557 42.845 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 598 842 3.0E-72 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 SUPERFAMILY SSF82866 295 548 1.07E-41 T 14-10-2018 HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Pfam PF02355 Protein export membrane protein 376 543 5.7E-19 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Pfam PF02355 Protein export membrane protein 674 851 5.2E-60 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 46 541 2.5E-142 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Pfam PF07549 SecD/SecF GG Motif 44 61 0.0012 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Pfam PF07549 SecD/SecF GG Motif 598 616 0.0023 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Gene3D G3DSA:3.30.1360.200 250 369 2.0E-40 T 14-10-2018 HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 PRINTS PR01755 Bacterial translocase SecF protein signature 710 724 2.1E-21 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 PRINTS PR01755 Bacterial translocase SecF protein signature 758 776 2.1E-21 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 PRINTS PR01755 Bacterial translocase SecF protein signature 595 610 2.1E-21 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 PRINTS PR01755 Bacterial translocase SecF protein signature 790 805 2.1E-21 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 658 839 5.0E-48 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 305 535 7.8E-77 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 565 853 24.965 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Gene3D G3DSA:1.20.1640.10 652 855 3.0E-14 T 14-10-2018 HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 SUPERFAMILY SSF82866 658 853 1.01E-38 T 14-10-2018 HL41_02845 d347849db1b9810f89c5f7877eb5979f 858 Gene3D G3DSA:3.30.70.3220 134 249 5.7E-22 T 14-10-2018 HL41_02230 8b63732fdc3f043041df760d4ce0dcb8 97 Gene3D G3DSA:3.30.70.20 19 97 1.4E-12 T 14-10-2018 HL41_02230 8b63732fdc3f043041df760d4ce0dcb8 97 Pfam PF00037 4Fe-4S binding domain 38 56 2.9E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_02230 8b63732fdc3f043041df760d4ce0dcb8 97 Pfam PF00037 4Fe-4S binding domain 74 91 1.1E-4 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_02230 8b63732fdc3f043041df760d4ce0dcb8 97 SUPERFAMILY SSF54862 18 95 9.21E-18 T 14-10-2018 HL41_02230 8b63732fdc3f043041df760d4ce0dcb8 97 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_02230 8b63732fdc3f043041df760d4ce0dcb8 97 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 20 96 3.5E-29 T 14-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 HL41_06445 31b7201afda010a502a714a559087825 322 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 25 321 16.274 T 14-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 HL41_06445 31b7201afda010a502a714a559087825 322 SMART SM00028 275 308 240.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_06445 31b7201afda010a502a714a559087825 322 SMART SM00028 201 234 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_06445 31b7201afda010a502a714a559087825 322 SMART SM00028 238 271 0.92 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_06445 31b7201afda010a502a714a559087825 322 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 201 316 5.7E-28 T 14-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal HL41_06445 31b7201afda010a502a714a559087825 322 Gene3D G3DSA:1.25.40.10 201 320 2.9E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_06445 31b7201afda010a502a714a559087825 322 Pfam PF13174 Tetratricopeptide repeat 277 308 2.8E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_06445 31b7201afda010a502a714a559087825 322 Pfam PF13432 Tetratricopeptide repeat 205 267 2.2E-12 T 14-10-2018 HL41_06445 31b7201afda010a502a714a559087825 322 SUPERFAMILY SSF48452 204 314 1.64E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_07900 6fa32c62072640e5dc74c0fccb14671f 375 SUPERFAMILY SSF53756 28 370 6.8E-64 T 14-10-2018 HL41_07900 6fa32c62072640e5dc74c0fccb14671f 375 Gene3D G3DSA:3.40.50.2000 187 373 5.7E-32 T 14-10-2018 HL41_07900 6fa32c62072640e5dc74c0fccb14671f 375 Gene3D G3DSA:3.40.50.2000 21 182 1.0E-30 T 14-10-2018 HL41_07900 6fa32c62072640e5dc74c0fccb14671f 375 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 98 335 3.4E-18 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 HL41_04700 9b3c0ded278dd912d95d5ab6e9872786 402 Pfam PF02371 Transposase IS116/IS110/IS902 family 263 347 1.4E-23 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HL41_04700 9b3c0ded278dd912d95d5ab6e9872786 402 Pfam PF01548 Transposase 5 156 1.8E-27 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 Gene3D G3DSA:1.25.40.10 69 231 3.8E-36 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SMART SM00671 205 236 34.0 T 14-10-2018 IPR006597 Sel1-like repeat HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SMART SM00671 135 166 0.39 T 14-10-2018 IPR006597 Sel1-like repeat HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SMART SM00671 101 132 280.0 T 14-10-2018 IPR006597 Sel1-like repeat HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SMART SM00671 239 270 340.0 T 14-10-2018 IPR006597 Sel1-like repeat HL41_05765 05db80c3782918d3c2648573a0b8a248 295 Pfam PF14559 Tetratricopeptide repeat 217 276 4.0E-7 T 14-10-2018 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 Pfam PF13181 Tetratricopeptide repeat 175 202 0.045 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 Pfam PF13181 Tetratricopeptide repeat 102 134 3.0E-8 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SMART SM00028 205 238 0.081 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SMART SM00028 171 204 4.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SMART SM00028 239 272 0.87 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SMART SM00028 135 168 2.6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SMART SM00028 101 134 1.0E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 Pfam PF07719 Tetratricopeptide repeat 136 163 3.6E-5 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 SUPERFAMILY SSF48452 84 274 1.86E-29 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_05765 05db80c3782918d3c2648573a0b8a248 295 Gene3D G3DSA:1.25.40.10 232 285 3.8E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_06255 62d49c0367aabd79794a620265cdf0d7 389 Gene3D G3DSA:3.30.2350.20 104 380 6.2E-53 T 14-10-2018 HL41_06255 62d49c0367aabd79794a620265cdf0d7 389 Gene3D G3DSA:3.30.70.3160 21 103 6.2E-53 T 14-10-2018 HL41_06255 62d49c0367aabd79794a620265cdf0d7 389 Gene3D G3DSA:1.10.1510.30 147 237 6.2E-53 T 14-10-2018 HL41_06255 62d49c0367aabd79794a620265cdf0d7 389 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 2 259 2.2E-55 T 14-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_06255 62d49c0367aabd79794a620265cdf0d7 389 PIRSF PIRSF037016 4 273 5.0E-34 T 14-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_06255 62d49c0367aabd79794a620265cdf0d7 389 PIRSF PIRSF037016 302 383 72.0 T 14-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_06255 62d49c0367aabd79794a620265cdf0d7 389 SUPERFAMILY SSF55120 2 383 8.2E-60 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_01340 2401baa21a5a45b08e20b6f44a4b5140 198 SUPERFAMILY SSF54713 57 198 1.83E-54 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 HL41_01340 2401baa21a5a45b08e20b6f44a4b5140 198 Pfam PF00889 Elongation factor TS 41 198 4.5E-42 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 HL41_01340 2401baa21a5a45b08e20b6f44a4b5140 198 Gene3D G3DSA:1.10.8.10 1 55 9.8E-26 T 14-10-2018 HL41_01340 2401baa21a5a45b08e20b6f44a4b5140 198 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HL41_01340 2401baa21a5a45b08e20b6f44a4b5140 198 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 96 3.7E-37 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HL41_01340 2401baa21a5a45b08e20b6f44a4b5140 198 SUPERFAMILY SSF46934 3 56 2.7E-18 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 HL41_01340 2401baa21a5a45b08e20b6f44a4b5140 198 Gene3D G3DSA:3.30.479.20 60 197 3.8E-60 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 HL41_01340 2401baa21a5a45b08e20b6f44a4b5140 198 Hamap MF_00050 Elongation factor Ts [tsf]. 1 198 47.562 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HL41_01340 2401baa21a5a45b08e20b6f44a4b5140 198 Gene3D G3DSA:1.10.286.20 112 156 3.8E-60 T 14-10-2018 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 PIRSF PIRSF001400 1 425 1.8E-192 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 SMART SM01193 4 134 5.6E-91 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 Hamap MF_00318 Enolase [eno]. 2 411 44.747 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 423 6.1E-128 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 424 1.0E-203 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 Pfam PF03952 Enolase, N-terminal domain 4 134 6.7E-59 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 ProSitePatterns PS00164 Enolase signature. 334 347 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 SUPERFAMILY SSF54826 3 137 2.46E-55 T 14-10-2018 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 SUPERFAMILY SSF51604 139 423 1.77E-126 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 PRINTS PR00148 Enolase signature 107 123 1.2E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 PRINTS PR00148 Enolase signature 161 174 1.2E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 PRINTS PR00148 Enolase signature 311 322 1.2E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 PRINTS PR00148 Enolase signature 334 348 1.2E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 PRINTS PR00148 Enolase signature 363 380 1.2E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 PRINTS PR00148 Enolase signature 37 51 1.2E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 Gene3D G3DSA:3.30.390.10 1 127 1.0E-56 T 14-10-2018 IPR029017 Enolase-like, N-terminal HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 SMART SM01192 139 425 9.2E-208 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06595 f24fcabd7c452749b6a2c6305f47b97a 426 Gene3D G3DSA:3.20.20.120 129 426 5.4E-135 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily HL41_03795 5ecc06a733fd46f809ed688cf367efd1 101 SMART SM00858 15 90 6.2E-16 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HL41_03795 5ecc06a733fd46f809ed688cf367efd1 101 Gene3D G3DSA:3.90.1210.30 8 92 2.2E-32 T 14-10-2018 HL41_03795 5ecc06a733fd46f809ed688cf367efd1 101 Pfam PF08666 SAF domain 15 90 1.5E-20 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HL41_06690 a86017b9ba16523a89a90bbcda96e30f 60 Gene3D G3DSA:3.30.70.270 3 59 4.0E-9 T 14-10-2018 HL41_06690 a86017b9ba16523a89a90bbcda96e30f 60 SUPERFAMILY SSF55073 13 59 2.59E-7 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_06690 a86017b9ba16523a89a90bbcda96e30f 60 Pfam PF00990 Diguanylate cyclase, GGDEF domain 17 57 4.8E-6 T 14-10-2018 IPR000160 GGDEF domain HL41_05005 ca75096ac5471a76060c81f5e7e4dc7f 551 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 460 471 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HL41_05005 ca75096ac5471a76060c81f5e7e4dc7f 551 SUPERFAMILY SSF52016 372 550 1.41E-63 T 14-10-2018 HL41_05005 ca75096ac5471a76060c81f5e7e4dc7f 551 SUPERFAMILY SSF143975 1 371 3.66E-147 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HL41_05005 ca75096ac5471a76060c81f5e7e4dc7f 551 Gene3D G3DSA:3.50.30.80 372 523 2.8E-60 T 14-10-2018 HL41_05005 ca75096ac5471a76060c81f5e7e4dc7f 551 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HL41_05005 ca75096ac5471a76060c81f5e7e4dc7f 551 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 550 2.4E-253 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HL41_05005 ca75096ac5471a76060c81f5e7e4dc7f 551 Pfam PF00920 Dehydratase family 31 548 6.0E-235 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HL41_05005 ca75096ac5471a76060c81f5e7e4dc7f 551 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 551 48.922 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HL41_04045 979b84fc8f31148d089f23f774f40f30 291 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 4 291 27.511 T 14-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 HL41_04045 979b84fc8f31148d089f23f774f40f30 291 Gene3D G3DSA:3.30.70.120 220 291 4.5E-20 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HL41_04045 979b84fc8f31148d089f23f774f40f30 291 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 189 6.2E-49 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 HL41_04045 979b84fc8f31148d089f23f774f40f30 291 Pfam PF08029 HisG, C-terminal domain 219 289 5.3E-24 T 14-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 HL41_04045 979b84fc8f31148d089f23f774f40f30 291 SUPERFAMILY SSF53850 4 215 1.0E-56 T 14-10-2018 HL41_04045 979b84fc8f31148d089f23f774f40f30 291 Gene3D G3DSA:3.40.190.10 7 206 4.6E-54 T 14-10-2018 HL41_04045 979b84fc8f31148d089f23f774f40f30 291 Pfam PF01634 ATP phosphoribosyltransferase 51 212 7.2E-40 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 HL41_04045 979b84fc8f31148d089f23f774f40f30 291 Gene3D G3DSA:3.40.190.10 90 184 4.6E-54 T 14-10-2018 HL41_04045 979b84fc8f31148d089f23f774f40f30 291 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 191 291 6.6E-33 T 14-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 HL41_04045 979b84fc8f31148d089f23f774f40f30 291 SUPERFAMILY SSF54913 220 291 1.78E-20 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta HL41_03520 f316056736d888433c91277ae446be60 442 SUPERFAMILY SSF52540 63 275 2.01E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03520 f316056736d888433c91277ae446be60 442 PRINTS PR01874 DNA repair protein radA signature 204 232 1.1E-87 T 14-10-2018 HL41_03520 f316056736d888433c91277ae446be60 442 PRINTS PR01874 DNA repair protein radA signature 239 265 1.1E-87 T 14-10-2018 HL41_03520 f316056736d888433c91277ae446be60 442 PRINTS PR01874 DNA repair protein radA signature 116 133 1.1E-87 T 14-10-2018 HL41_03520 f316056736d888433c91277ae446be60 442 PRINTS PR01874 DNA repair protein radA signature 5 29 1.1E-87 T 14-10-2018 HL41_03520 f316056736d888433c91277ae446be60 442 PRINTS PR01874 DNA repair protein radA signature 74 102 1.1E-87 T 14-10-2018 HL41_03520 f316056736d888433c91277ae446be60 442 PRINTS PR01874 DNA repair protein radA signature 309 332 1.1E-87 T 14-10-2018 HL41_03520 f316056736d888433c91277ae446be60 442 PRINTS PR01874 DNA repair protein radA signature 165 189 1.1E-87 T 14-10-2018 HL41_03520 f316056736d888433c91277ae446be60 442 TIGRFAM TIGR00416 sms: DNA repair protein RadA 2 436 2.5E-162 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 HL41_03520 f316056736d888433c91277ae446be60 442 Pfam PF13541 Subunit ChlI of Mg-chelatase 331 415 1.9E-11 T 14-10-2018 HL41_03520 f316056736d888433c91277ae446be60 442 Gene3D G3DSA:3.30.230.10 319 442 2.6E-21 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_03520 f316056736d888433c91277ae446be60 442 SUPERFAMILY SSF54211 246 442 1.59E-36 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_03520 f316056736d888433c91277ae446be60 442 Gene3D G3DSA:3.40.50.300 58 280 1.4E-41 T 14-10-2018 HL41_03520 f316056736d888433c91277ae446be60 442 Hamap MF_01498 DNA repair protein RadA [radA]. 16 442 40.868 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 HL41_03520 f316056736d888433c91277ae446be60 442 SMART SM00382 82 235 9.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_03520 f316056736d888433c91277ae446be60 442 Pfam PF13481 AAA domain 76 212 3.0E-11 T 14-10-2018 HL41_05065 07c62f7b43e83d690b1296a1f757d045 396 ProDom PD011569 METAL-BINDING IRON IRON-SULFUR 4FE-4S FERREDOXIN OXIDOREDUCTASE DOMAIN ELECTRON METHANOGENESIS A 25 302 8.0E-115 T 14-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation HL41_05065 07c62f7b43e83d690b1296a1f757d045 396 Pfam PF01837 Homocysteine biosynthesis enzyme, sulfur-incorporation 23 380 1.7E-149 T 14-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation HL41_02680 310536ebd22c3c2f7854830fee19a8f2 416 SUPERFAMILY SSF48695 15 290 6.01E-21 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_02680 310536ebd22c3c2f7854830fee19a8f2 416 Gene3D G3DSA:1.10.1130.10 228 300 2.1E-5 T 14-10-2018 HL41_08425 dccacb5973c11a607880fc84345e41e8 458 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 67 78 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08425 dccacb5973c11a607880fc84345e41e8 458 Pfam PF13237 4Fe-4S dicluster domain 30 78 1.3E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_08425 dccacb5973c11a607880fc84345e41e8 458 Gene3D G3DSA:3.30.70.20 32 82 1.4E-126 T 14-10-2018 HL41_08425 dccacb5973c11a607880fc84345e41e8 458 SUPERFAMILY SSF53920 66 441 5.1E-90 T 14-10-2018 IPR009016 Iron hydrogenase HL41_08425 dccacb5973c11a607880fc84345e41e8 458 SUPERFAMILY SSF54862 26 87 1.7E-18 T 14-10-2018 HL41_08425 dccacb5973c11a607880fc84345e41e8 458 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 101 436 1.3E-73 T 14-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal HL41_08425 dccacb5973c11a607880fc84345e41e8 458 Gene3D G3DSA:3.40.950.10 148 430 1.4E-126 T 14-10-2018 HL41_08425 dccacb5973c11a607880fc84345e41e8 458 Gene3D G3DSA:3.40.50.1780 83 439 1.4E-126 T 14-10-2018 HL41_02660 4c7ee280c06383d9edcc8125a44bf134 417 SUPERFAMILY SSF53756 53 417 1.92E-16 T 14-10-2018 HL41_02660 4c7ee280c06383d9edcc8125a44bf134 417 Gene3D G3DSA:3.40.50.11720 32 207 7.3E-49 T 14-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 HL41_02660 4c7ee280c06383d9edcc8125a44bf134 417 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 43 208 3.5E-58 T 14-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 HL41_02660 4c7ee280c06383d9edcc8125a44bf134 417 Gene3D G3DSA:3.40.50.2000 218 399 2.5E-46 T 14-10-2018 HL41_07275 cbef3ccec5f98bcb81b699d77e13d6bc 339 Gene3D G3DSA:3.20.20.70 36 338 5.7E-72 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_07275 cbef3ccec5f98bcb81b699d77e13d6bc 339 PIRSF PIRSF000138 2 194 6.6E-18 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 HL41_07275 cbef3ccec5f98bcb81b699d77e13d6bc 339 PIRSF PIRSF000138 184 339 1.6E-55 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 HL41_07275 cbef3ccec5f98bcb81b699d77e13d6bc 339 SUPERFAMILY SSF51395 37 336 4.39E-53 T 14-10-2018 HL41_07275 cbef3ccec5f98bcb81b699d77e13d6bc 339 Pfam PF01070 FMN-dependent dehydrogenase 37 91 6.6E-10 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 HL41_07275 cbef3ccec5f98bcb81b699d77e13d6bc 339 Pfam PF01070 FMN-dependent dehydrogenase 194 336 3.3E-51 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 HL41_08395 7f8d33865f4941b21eae545c03da4db4 376 Gene3D G3DSA:1.10.10.10 263 376 3.3E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_08395 7f8d33865f4941b21eae545c03da4db4 376 SUPERFAMILY SSF46785 268 375 2.99E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_08395 7f8d33865f4941b21eae545c03da4db4 376 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 8 252 6.6E-35 T 14-10-2018 IPR017039 Virulence factor BrkB HL41_08395 7f8d33865f4941b21eae545c03da4db4 376 Pfam PF03631 Virulence factor BrkB 18 253 2.7E-41 T 14-10-2018 IPR017039 Virulence factor BrkB HL41_08395 7f8d33865f4941b21eae545c03da4db4 376 Pfam PF02082 Transcriptional regulator 268 337 5.1E-6 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type HL41_00070 095430c8916c284e78479da250c143eb 509 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 500 3.1E-190 T 14-10-2018 IPR004482 Mg chelatase-related protein HL41_00070 095430c8916c284e78479da250c143eb 509 SMART SM00382 210 393 7.9E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_00070 095430c8916c284e78479da250c143eb 509 Gene3D G3DSA:3.30.230.10 12 169 2.7E-15 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_00070 095430c8916c284e78479da250c143eb 509 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 290 304 4.2E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 HL41_00070 095430c8916c284e78479da250c143eb 509 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 318 331 4.2E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 HL41_00070 095430c8916c284e78479da250c143eb 509 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 209 224 4.2E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 HL41_00070 095430c8916c284e78479da250c143eb 509 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 395 1.3E-95 T 14-10-2018 IPR000523 Magnesium chelatase ChlI domain HL41_00070 095430c8916c284e78479da250c143eb 509 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 142 9.8E-47 T 14-10-2018 HL41_00070 095430c8916c284e78479da250c143eb 509 SUPERFAMILY SSF54211 7 168 3.45E-37 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_00070 095430c8916c284e78479da250c143eb 509 SUPERFAMILY SSF52540 190 501 2.48E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00070 095430c8916c284e78479da250c143eb 509 Gene3D G3DSA:3.40.50.300 187 505 8.3E-68 T 14-10-2018 HL41_00070 095430c8916c284e78479da250c143eb 509 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 407 500 7.9E-32 T 14-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain HL41_06280 bac853564d71c6d83aaa470382fb4b02 235 SUPERFAMILY SSF53448 3 230 4.1E-59 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_06280 bac853564d71c6d83aaa470382fb4b02 235 Pfam PF00483 Nucleotidyl transferase 5 230 3.3E-32 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HL41_06280 bac853564d71c6d83aaa470382fb4b02 235 Gene3D G3DSA:3.90.550.10 1 234 1.2E-62 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_05875 ed62b005732841610bb70152c34cd048 186 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 179 5.1E-31 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 HL41_05875 ed62b005732841610bb70152c34cd048 186 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 184 19.051 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 HL41_05875 ed62b005732841610bb70152c34cd048 186 Gene3D G3DSA:3.40.50.300 1 186 1.7E-49 T 14-10-2018 HL41_05875 ed62b005732841610bb70152c34cd048 186 SUPERFAMILY SSF52540 1 183 1.03E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05875 ed62b005732841610bb70152c34cd048 186 Pfam PF01121 Dephospho-CoA kinase 4 165 3.2E-28 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 HL41_08495 60a093833d24db96c3c70227c209351e 197 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 24 184 7.5E-14 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_08495 60a093833d24db96c3c70227c209351e 197 Gene3D G3DSA:3.40.50.300 1 194 1.7E-52 T 14-10-2018 HL41_08495 60a093833d24db96c3c70227c209351e 197 SUPERFAMILY SSF52540 4 192 8.69E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08495 60a093833d24db96c3c70227c209351e 197 Pfam PF01926 50S ribosome-binding GTPase 24 142 6.3E-21 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_08495 60a093833d24db96c3c70227c209351e 197 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 10 192 25.341 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 HL41_08495 60a093833d24db96c3c70227c209351e 197 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 6 188 8.5E-61 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 SUPERFAMILY SSF56037 331 451 9.42E-16 T 14-10-2018 HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 381 421 7.8E-13 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 Pfam PF11734 TilS substrate C-terminal domain 380 448 1.2E-10 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 SUPERFAMILY SSF52402 2 210 1.63E-53 T 14-10-2018 HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 Gene3D G3DSA:3.40.50.620 1 211 4.8E-64 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 SMART SM00977 379 451 8.5E-14 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 6 314 23.864 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 205 9.7E-53 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 SUPERFAMILY SSF82829 214 319 4.45E-11 T 14-10-2018 HL41_01605 6ab50edbd4281c18baed2481cc5cc557 455 Pfam PF01171 PP-loop family 22 201 5.9E-49 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 SUPERFAMILY SSF63411 233 415 7.33E-31 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 Gene3D G3DSA:3.30.830.10 17 229 4.1E-75 T 14-10-2018 HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 Gene3D G3DSA:3.30.830.10 444 652 2.9E-41 T 14-10-2018 HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 Pfam PF00675 Insulinase (Peptidase family M16) 460 595 1.7E-10 T 14-10-2018 IPR011765 Peptidase M16, N-terminal HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 Pfam PF00675 Insulinase (Peptidase family M16) 33 171 5.8E-36 T 14-10-2018 IPR011765 Peptidase M16, N-terminal HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 Gene3D G3DSA:3.30.830.10 658 846 3.8E-44 T 14-10-2018 HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 SUPERFAMILY SSF63411 440 645 5.72E-44 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 Pfam PF05193 Peptidase M16 inactive domain 178 355 4.4E-34 T 14-10-2018 IPR007863 Peptidase M16, C-terminal HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 Pfam PF05193 Peptidase M16 inactive domain 606 780 7.0E-32 T 14-10-2018 IPR007863 Peptidase M16, C-terminal HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 SUPERFAMILY SSF63411 669 846 3.51E-34 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 46 69 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 SUPERFAMILY SSF63411 15 227 1.5E-66 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HL41_07700 c0d6d2c99d8a25dad85c3ad061e33c12 846 Gene3D G3DSA:3.30.830.10 231 424 1.8E-38 T 14-10-2018 HL41_00890 de5a04ef3b68c8ba4f0efb81320b030c 620 Pfam PF14574 Domain of unknown function (DUF4445) 195 602 9.2E-137 T 14-10-2018 IPR027980 Protein of unknown function DUF4445 HL41_00890 de5a04ef3b68c8ba4f0efb81320b030c 620 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 70 6.4E-7 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HL41_00890 de5a04ef3b68c8ba4f0efb81320b030c 620 Gene3D G3DSA:2.40.50.570 107 188 5.2E-12 T 14-10-2018 HL41_00890 de5a04ef3b68c8ba4f0efb81320b030c 620 Gene3D G3DSA:3.30.420.480 194 362 1.8E-45 T 14-10-2018 HL41_00890 de5a04ef3b68c8ba4f0efb81320b030c 620 Gene3D G3DSA:3.10.20.30 2 83 8.7E-15 T 14-10-2018 IPR012675 Beta-grasp domain superfamily HL41_00890 de5a04ef3b68c8ba4f0efb81320b030c 620 SUPERFAMILY SSF54292 3 80 2.36E-16 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 HL41_08765 50df17246ef9b5e8ca33b447e123b87f 116 PIRSF PIRSF004761 1 116 2.0E-31 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 HL41_08765 50df17246ef9b5e8ca33b447e123b87f 116 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 112 3.0E-27 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 HL41_08765 50df17246ef9b5e8ca33b447e123b87f 116 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 111 2.1E-29 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 HL41_08765 50df17246ef9b5e8ca33b447e123b87f 116 Gene3D G3DSA:3.30.2320.80 1 115 1.9E-31 T 14-10-2018 HL41_08765 50df17246ef9b5e8ca33b447e123b87f 116 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 14-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site HL41_08765 50df17246ef9b5e8ca33b447e123b87f 116 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 113 19.917 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 HL41_00350 640752f13ae43c5ef1ed695ef2cdc379 149 TIGRFAM TIGR03153 cytochr_NrfH: cytochrome c nitrite reductase, small subunit 6 138 2.8E-44 T 14-10-2018 IPR017571 Cytochrome c nitrite reductase, small subunit GO:0016021|GO:0022900 HL41_00350 640752f13ae43c5ef1ed695ef2cdc379 149 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 7 137 1.6E-12 T 14-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal HL41_00350 640752f13ae43c5ef1ed695ef2cdc379 149 SUPERFAMILY SSF48695 13 140 2.67E-19 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_00350 640752f13ae43c5ef1ed695ef2cdc379 149 Gene3D G3DSA:1.10.3820.10 1 148 8.6E-35 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily HL41_02710 b55cd2b36f5845bc90f4fbf77b637e52 295 SMART SM00271 8 70 0.0014 T 14-10-2018 IPR001623 DnaJ domain HL41_02710 b55cd2b36f5845bc90f4fbf77b637e52 295 Gene3D G3DSA:1.10.287.110 1 91 2.6E-9 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_02710 b55cd2b36f5845bc90f4fbf77b637e52 295 SUPERFAMILY SSF46565 6 75 7.98E-10 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_04635 d8418fe9e3bead3ccd2f25c549bf36ce 506 SUPERFAMILY SSF56112 17 286 9.01E-9 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily HL41_04635 d8418fe9e3bead3ccd2f25c549bf36ce 506 SUPERFAMILY SSF52540 328 504 4.04E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04635 d8418fe9e3bead3ccd2f25c549bf36ce 506 Gene3D G3DSA:3.40.50.300 327 505 4.7E-31 T 14-10-2018 HL41_04635 d8418fe9e3bead3ccd2f25c549bf36ce 506 Pfam PF13671 AAA domain 330 478 6.5E-24 T 14-10-2018 HL41_00105 18535f72c84b6dd0ff5f8fe1f4a992f8 274 Pfam PF00588 SpoU rRNA Methylase family 17 166 2.4E-34 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HL41_00105 18535f72c84b6dd0ff5f8fe1f4a992f8 274 PIRSF PIRSF004808 11 249 8.1E-66 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 HL41_00105 18535f72c84b6dd0ff5f8fe1f4a992f8 274 Gene3D G3DSA:1.10.8.590 177 256 2.2E-9 T 14-10-2018 HL41_00105 18535f72c84b6dd0ff5f8fe1f4a992f8 274 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 14 241 7.7E-56 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 HL41_00105 18535f72c84b6dd0ff5f8fe1f4a992f8 274 Gene3D G3DSA:3.40.1280.10 13 175 9.0E-52 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HL41_00105 18535f72c84b6dd0ff5f8fe1f4a992f8 274 SUPERFAMILY SSF75217 8 192 2.03E-36 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases HL41_05455 e247707f00a1f703399b2a4a50accd38 399 SUPERFAMILY SSF52540 8 231 1.38E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05455 e247707f00a1f703399b2a4a50accd38 399 Pfam PF03144 Elongation factor Tu domain 2 230 298 3.0E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site HL41_05455 e247707f00a1f703399b2a4a50accd38 399 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 145 8.7E-14 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 Gene3D G3DSA:2.40.30.10 343 398 4.5E-30 T 14-10-2018 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 Pfam PF03143 Elongation factor Tu C-terminal domain 303 397 3.5E-36 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal HL41_05455 e247707f00a1f703399b2a4a50accd38 399 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 399 2.4E-221 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 Gene3D G3DSA:2.40.30.10 211 339 1.4E-54 T 14-10-2018 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 SUPERFAMILY SSF50447 210 306 2.16E-31 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_05455 e247707f00a1f703399b2a4a50accd38 399 Pfam PF00009 Elongation factor Tu GTP binding domain 10 206 9.0E-58 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 SUPERFAMILY SSF50465 303 398 8.92E-38 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HL41_05455 e247707f00a1f703399b2a4a50accd38 399 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 399 60.206 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HL41_05455 e247707f00a1f703399b2a4a50accd38 399 Gene3D G3DSA:3.40.50.300 1 208 5.1E-67 T 14-10-2018 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 SUPERFAMILY SSF52540 8 231 1.38E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08955 e247707f00a1f703399b2a4a50accd38 399 Pfam PF03144 Elongation factor Tu domain 2 230 298 3.0E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site HL41_08955 e247707f00a1f703399b2a4a50accd38 399 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 145 8.7E-14 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 Gene3D G3DSA:2.40.30.10 343 398 4.5E-30 T 14-10-2018 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 Pfam PF03143 Elongation factor Tu C-terminal domain 303 397 3.5E-36 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal HL41_08955 e247707f00a1f703399b2a4a50accd38 399 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 399 2.4E-221 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 Gene3D G3DSA:2.40.30.10 211 339 1.4E-54 T 14-10-2018 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 SUPERFAMILY SSF50447 210 306 2.16E-31 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_08955 e247707f00a1f703399b2a4a50accd38 399 Pfam PF00009 Elongation factor Tu GTP binding domain 10 206 9.0E-58 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.1E-23 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 SUPERFAMILY SSF50465 303 398 8.92E-38 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HL41_08955 e247707f00a1f703399b2a4a50accd38 399 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 399 60.206 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HL41_08955 e247707f00a1f703399b2a4a50accd38 399 Gene3D G3DSA:3.40.50.300 1 208 5.1E-67 T 14-10-2018 HL41_04445 49725917e2e15a4b6f6babcb29b09a52 486 SUPERFAMILY SSF50249 38 124 4.12E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_04445 49725917e2e15a4b6f6babcb29b09a52 486 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 12 423 2.8E-152 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 HL41_04445 49725917e2e15a4b6f6babcb29b09a52 486 SMART SM00316 36 119 2.4E-7 T 14-10-2018 IPR022967 RNA-binding domain, S1 HL41_04445 49725917e2e15a4b6f6babcb29b09a52 486 Gene3D G3DSA:3.40.1260.20 399 485 1.4E-5 T 14-10-2018 HL41_04445 49725917e2e15a4b6f6babcb29b09a52 486 Pfam PF10150 Ribonuclease E/G family 121 389 2.0E-104 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 HL41_04445 49725917e2e15a4b6f6babcb29b09a52 486 Gene3D G3DSA:2.40.50.140 30 125 8.9E-27 T 14-10-2018 HL41_02475 378625730dcf9938e76a33ef27bd92cf 407 Hamap MF_01402_B 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 13 398 54.089 T 14-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_02475 378625730dcf9938e76a33ef27bd92cf 407 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 47 223 4.7E-48 T 14-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_02475 378625730dcf9938e76a33ef27bd92cf 407 PIRSF PIRSF006392 10 403 4.4E-127 T 14-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_02475 378625730dcf9938e76a33ef27bd92cf 407 Gene3D G3DSA:3.30.70.2130 88 236 1.1E-99 T 14-10-2018 HL41_02475 378625730dcf9938e76a33ef27bd92cf 407 Gene3D G3DSA:3.40.720.10 17 393 1.1E-99 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 HL41_02475 378625730dcf9938e76a33ef27bd92cf 407 Pfam PF01676 Metalloenzyme superfamily 14 394 5.1E-39 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 HL41_02475 378625730dcf9938e76a33ef27bd92cf 407 SUPERFAMILY SSF53649 14 372 5.67E-32 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 HL41_02475 378625730dcf9938e76a33ef27bd92cf 407 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 18 396 6.3E-86 T 14-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_06045 cc2be0cb7a0a1b9da25c6a7e35f66dc4 110 Pfam PF04023 FeoA domain 12 103 4.6E-14 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HL41_06045 cc2be0cb7a0a1b9da25c6a7e35f66dc4 110 SUPERFAMILY SSF50037 52 103 1.3E-10 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal HL41_06045 cc2be0cb7a0a1b9da25c6a7e35f66dc4 110 SMART SM00899 11 105 1.1E-8 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HL41_06045 cc2be0cb7a0a1b9da25c6a7e35f66dc4 110 Gene3D G3DSA:2.30.30.90 47 105 2.1E-12 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain HL41_07620 3ab124edd52f8589670172e3aee92e3c 452 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 64 440 5.7E-83 T 14-10-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel HL41_07620 3ab124edd52f8589670172e3aee92e3c 452 Gene3D G3DSA:3.20.20.20 1 318 4.6E-91 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_07620 3ab124edd52f8589670172e3aee92e3c 452 Gene3D G3DSA:3.40.50.11600 319 447 1.6E-48 T 14-10-2018 HL41_07620 3ab124edd52f8589670172e3aee92e3c 452 Pfam PF04060 Putative Fe-S cluster 12 44 4.0E-14 T 14-10-2018 IPR007202 4Fe-4S domain GO:0051536 HL41_07715 63edd3f334d81599d7c0388383230b5a 569 Gene3D G3DSA:3.40.50.300 3 214 1.8E-30 T 14-10-2018 HL41_07715 63edd3f334d81599d7c0388383230b5a 569 SMART SM00487 17 225 2.5E-22 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HL41_07715 63edd3f334d81599d7c0388383230b5a 569 Gene3D G3DSA:3.40.50.300 229 393 3.1E-14 T 14-10-2018 HL41_07715 63edd3f334d81599d7c0388383230b5a 569 Pfam PF00271 Helicase conserved C-terminal domain 241 357 2.9E-6 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_07715 63edd3f334d81599d7c0388383230b5a 569 Pfam PF00270 DEAD/DEAH box helicase 23 198 6.4E-21 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HL41_07715 63edd3f334d81599d7c0388383230b5a 569 SUPERFAMILY SSF52540 28 370 8.39E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07715 63edd3f334d81599d7c0388383230b5a 569 SMART SM00490 267 358 5.5E-4 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_07715 63edd3f334d81599d7c0388383230b5a 569 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 39 393 7.4E-66 T 14-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core HL41_06625 071ca726d9b6b2bbb6c335e8e6a13bff 65 Gene3D G3DSA:2.20.28.10 6 61 7.8E-24 T 14-10-2018 HL41_06625 071ca726d9b6b2bbb6c335e8e6a13bff 65 Pfam PF00301 Rubredoxin 8 55 9.6E-21 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 HL41_06625 071ca726d9b6b2bbb6c335e8e6a13bff 65 PRINTS PR00163 Rubredoxin signature 39 55 4.9E-8 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 HL41_06625 071ca726d9b6b2bbb6c335e8e6a13bff 65 PRINTS PR00163 Rubredoxin signature 9 25 4.9E-8 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 HL41_06625 071ca726d9b6b2bbb6c335e8e6a13bff 65 SUPERFAMILY SSF57802 6 59 5.89E-20 T 14-10-2018 HL41_06625 071ca726d9b6b2bbb6c335e8e6a13bff 65 PIRSF PIRSF000071 1 64 1.7E-23 T 14-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 HL41_06625 071ca726d9b6b2bbb6c335e8e6a13bff 65 ProSitePatterns PS00202 Rubredoxin signature. 39 49 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 HL41_01235 639f8d06ec9175c76703b8aee1cbb986 258 SUPERFAMILY SSF51556 4 256 4.61E-83 T 14-10-2018 IPR032466 Metal-dependent hydrolase HL41_01235 639f8d06ec9175c76703b8aee1cbb986 258 PIRSF PIRSF005902 1 258 5.4E-80 T 14-10-2018 IPR001130 TatD family GO:0016788 HL41_01235 639f8d06ec9175c76703b8aee1cbb986 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 4 255 1.3E-80 T 14-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 HL41_01235 639f8d06ec9175c76703b8aee1cbb986 258 Pfam PF01026 TatD related DNase 5 255 1.7E-73 T 14-10-2018 IPR001130 TatD family GO:0016788 HL41_01235 639f8d06ec9175c76703b8aee1cbb986 258 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 4 12 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HL41_01235 639f8d06ec9175c76703b8aee1cbb986 258 Gene3D G3DSA:3.20.20.140 1 257 2.6E-90 T 14-10-2018 HL41_07220 04ec505356e0e6856900a56c3f8bce64 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 9 130 1.2E-14 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 HL41_07220 04ec505356e0e6856900a56c3f8bce64 365 Pfam PF00557 Metallopeptidase family M24 141 347 1.9E-49 T 14-10-2018 IPR000994 Peptidase M24 HL41_07220 04ec505356e0e6856900a56c3f8bce64 365 SUPERFAMILY SSF55920 130 364 3.01E-59 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like HL41_07220 04ec505356e0e6856900a56c3f8bce64 365 Gene3D G3DSA:3.40.350.10 3 131 1.5E-26 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HL41_07220 04ec505356e0e6856900a56c3f8bce64 365 SUPERFAMILY SSF53092 3 130 1.4E-20 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HL41_07220 04ec505356e0e6856900a56c3f8bce64 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 317 329 2.1E-6 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_07220 04ec505356e0e6856900a56c3f8bce64 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 288 300 2.1E-6 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_07220 04ec505356e0e6856900a56c3f8bce64 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 217 233 2.1E-6 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_07220 04ec505356e0e6856900a56c3f8bce64 365 Gene3D G3DSA:3.90.230.10 132 359 2.0E-62 T 14-10-2018 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 SUPERFAMILY SSF56059 77 362 1.56E-40 T 14-10-2018 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 SMART SM00878 355 462 3.1E-13 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 300 307 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 Pfam PF02785 Biotin carboxylase C-terminal domain 355 450 2.0E-14 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 Gene3D G3DSA:3.30.1490.20 127 208 2.0E-91 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 Gene3D G3DSA:3.40.50.20 1 79 7.3E-28 T 14-10-2018 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 SUPERFAMILY SSF52440 2 109 7.19E-38 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 Gene3D G3DSA:3.30.470.20 80 450 2.0E-91 T 14-10-2018 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 341 2.5E-31 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 106 2.9E-34 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HL41_03085 fb8e5b74f8b9b038d5e3f681e6fab1be 463 SUPERFAMILY SSF51246 350 450 1.78E-18 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HL41_05490 cdc770fc9193e7ec8a01c5a6a748e49c 370 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 365 1.9E-113 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HL41_05490 cdc770fc9193e7ec8a01c5a6a748e49c 370 Gene3D G3DSA:3.90.1150.10 247 370 2.4E-40 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_05490 cdc770fc9193e7ec8a01c5a6a748e49c 370 Gene3D G3DSA:3.40.640.10 1 245 4.7E-86 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_05490 cdc770fc9193e7ec8a01c5a6a748e49c 370 PIRSF PIRSF000390 2 370 6.2E-105 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HL41_05490 cdc770fc9193e7ec8a01c5a6a748e49c 370 SUPERFAMILY SSF53383 12 369 3.76E-110 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_03590 057d98f91b35f41838e103d238448652 407 SUPERFAMILY SSF51735 1 200 2.71E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_03590 057d98f91b35f41838e103d238448652 407 Gene3D G3DSA:3.40.50.720 2 401 3.1E-100 T 14-10-2018 HL41_03590 057d98f91b35f41838e103d238448652 407 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1 117 4.6E-21 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_03590 057d98f91b35f41838e103d238448652 407 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 178 196 8.0E-15 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_03590 057d98f91b35f41838e103d238448652 407 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 132 145 8.0E-15 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_03590 057d98f91b35f41838e103d238448652 407 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 286 8.0E-15 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_03590 057d98f91b35f41838e103d238448652 407 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 314 329 8.0E-15 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_03590 057d98f91b35f41838e103d238448652 407 Gene3D G3DSA:3.30.360.10 185 388 3.1E-100 T 14-10-2018 HL41_03590 057d98f91b35f41838e103d238448652 407 SUPERFAMILY SSF55347 184 336 2.92E-33 T 14-10-2018 HL41_03590 057d98f91b35f41838e103d238448652 407 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 182 189 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_03590 057d98f91b35f41838e103d238448652 407 SMART SM00846 1 184 5.7E-36 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_03590 057d98f91b35f41838e103d238448652 407 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 189 349 7.3E-29 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_03135 7bb18d325d92b2bad21d5f573860c378 268 Hamap MF_00055 MEMO1 family protein . 1 268 53.379 T 14-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 HL41_03135 7bb18d325d92b2bad21d5f573860c378 268 SUPERFAMILY SSF53213 56 188 2.62E-5 T 14-10-2018 HL41_03135 7bb18d325d92b2bad21d5f573860c378 268 Gene3D G3DSA:3.40.830.10 1 268 1.9E-61 T 14-10-2018 HL41_03135 7bb18d325d92b2bad21d5f573860c378 268 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 266 4.1E-90 T 14-10-2018 HL41_03135 7bb18d325d92b2bad21d5f573860c378 268 Pfam PF01875 Memo-like protein 4 265 9.1E-68 T 14-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 HL41_07450 dd829f4cd35997687ad60b27bb7c860c 427 Gene3D G3DSA:3.20.20.140 57 368 1.5E-127 T 14-10-2018 HL41_07450 dd829f4cd35997687ad60b27bb7c860c 427 SUPERFAMILY SSF51338 1 416 6.18E-20 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HL41_07450 dd829f4cd35997687ad60b27bb7c860c 427 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 424 40.617 T 14-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_07450 dd829f4cd35997687ad60b27bb7c860c 427 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_07450 dd829f4cd35997687ad60b27bb7c860c 427 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 21 418 3.6E-119 T 14-10-2018 HL41_07450 dd829f4cd35997687ad60b27bb7c860c 427 ProSitePatterns PS00482 Dihydroorotase signature 1. 59 67 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_07450 dd829f4cd35997687ad60b27bb7c860c 427 SUPERFAMILY SSF51556 56 366 5.87E-103 T 14-10-2018 IPR032466 Metal-dependent hydrolase HL41_07450 dd829f4cd35997687ad60b27bb7c860c 427 Pfam PF01979 Amidohydrolase family 52 399 4.9E-22 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HL41_07450 dd829f4cd35997687ad60b27bb7c860c 427 Gene3D G3DSA:2.30.40.10 9 415 1.5E-127 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HL41_07175 7ad804cafa7d85839e1196a7026336f3 385 SUPERFAMILY SSF53383 2 382 1.02E-111 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_07175 7ad804cafa7d85839e1196a7026336f3 385 Gene3D G3DSA:3.90.1150.10 17 380 3.8E-129 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_07175 7ad804cafa7d85839e1196a7026336f3 385 Gene3D G3DSA:3.40.640.10 42 282 3.8E-129 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_07175 7ad804cafa7d85839e1196a7026336f3 385 Pfam PF00155 Aminotransferase class I and II 31 380 5.9E-65 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HL41_07175 7ad804cafa7d85839e1196a7026336f3 385 TIGRFAM TIGR03540 DapC_direct: LL-diaminopimelate aminotransferase 3 382 9.6E-193 T 14-10-2018 IPR019881 Diaminopimelate aminotransferase, DapL, Desulfovibrio-type GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 HL41_07695 600bc38044deaa3f38a67fe93099a38c 156 Gene3D G3DSA:3.40.50.300 1 150 4.3E-38 T 14-10-2018 HL41_07695 600bc38044deaa3f38a67fe93099a38c 156 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 8 128 5.1E-35 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HL41_07695 600bc38044deaa3f38a67fe93099a38c 156 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 9 138 1.1E-33 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HL41_07695 600bc38044deaa3f38a67fe93099a38c 156 SUPERFAMILY SSF52540 23 148 3.22E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03640 1fccc21138e936119cc2511a04903928 501 Pfam PF02602 Uroporphyrinogen-III synthase HemD 267 493 3.6E-62 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03640 1fccc21138e936119cc2511a04903928 501 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 HL41_03640 1fccc21138e936119cc2511a04903928 501 SUPERFAMILY SSF69618 253 500 1.96E-69 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HL41_03640 1fccc21138e936119cc2511a04903928 501 Gene3D G3DSA:3.40.50.10090 296 401 9.6E-28 T 14-10-2018 HL41_03640 1fccc21138e936119cc2511a04903928 501 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 HL41_03640 1fccc21138e936119cc2511a04903928 501 Gene3D G3DSA:3.40.50.10090 402 498 1.0E-18 T 14-10-2018 HL41_03640 1fccc21138e936119cc2511a04903928 501 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 215 3.1E-50 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 HL41_03640 1fccc21138e936119cc2511a04903928 501 PIRSF PIRSF036426 1 255 2.0E-107 T 14-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 HL41_03640 1fccc21138e936119cc2511a04903928 501 SUPERFAMILY SSF53790 2 255 2.49E-81 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 HL41_03640 1fccc21138e936119cc2511a04903928 501 Gene3D G3DSA:3.40.1010.10 2 119 3.3E-47 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 HL41_03640 1fccc21138e936119cc2511a04903928 501 Gene3D G3DSA:3.30.950.10 120 269 2.4E-54 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 HL41_03640 1fccc21138e936119cc2511a04903928 501 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 240 4.9E-101 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 HL41_03510 1cea139c810577a7db17206b54e98a3d 197 SMART SM00014 63 179 2.6E-22 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HL41_03510 1cea139c810577a7db17206b54e98a3d 197 SUPERFAMILY SSF48317 4 184 2.35E-33 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily HL41_03510 1cea139c810577a7db17206b54e98a3d 197 Pfam PF01569 PAP2 superfamily 63 184 1.4E-24 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HL41_03510 1cea139c810577a7db17206b54e98a3d 197 Gene3D G3DSA:1.20.144.10 8 197 6.3E-30 T 14-10-2018 HL41_03045 ef186bf04cd566802bfb0151fa2b38ee 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 141 165 4.0E-6 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_03045 ef186bf04cd566802bfb0151fa2b38ee 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 107 132 4.0E-6 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_03045 ef186bf04cd566802bfb0151fa2b38ee 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 4.0E-6 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_03045 ef186bf04cd566802bfb0151fa2b38ee 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 179 198 4.0E-6 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_03045 ef186bf04cd566802bfb0151fa2b38ee 267 PIRSF PIRSF006648 2 259 6.6E-14 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_03045 ef186bf04cd566802bfb0151fa2b38ee 267 Pfam PF01061 ABC-2 type transporter 32 222 6.4E-12 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 SUPERFAMILY SSF52540 36 574 1.15E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 Hamap MF_00204 UvrABC system protein B [uvrB]. 6 663 43.871 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 SMART SM00487 12 429 6.6E-34 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 7 661 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 Pfam PF00271 Helicase conserved C-terminal domain 442 547 7.0E-18 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 SUPERFAMILY SSF46600 627 664 8.11E-10 T 14-10-2018 IPR036876 UVR domain superfamily HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 Gene3D G3DSA:4.10.860.10 616 666 3.7E-9 T 14-10-2018 HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 SMART SM00490 463 549 5.7E-20 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 Gene3D G3DSA:3.40.50.300 418 599 1.4E-51 T 14-10-2018 HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 Gene3D G3DSA:3.40.50.300 1 236 8.2E-77 T 14-10-2018 HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 Pfam PF12344 Ultra-violet resistance protein B 555 596 9.6E-20 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 Pfam PF04851 Type III restriction enzyme, res subunit 15 89 2.6E-11 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 Pfam PF02151 UvrB/uvrC motif 628 662 2.5E-7 T 14-10-2018 IPR001943 UVR domain GO:0005515 HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 SUPERFAMILY SSF52540 7 418 6.05E-137 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08035 63d24d3bdee03eb76df3f802f5aad7a6 668 Gene3D G3DSA:3.40.50.300 280 417 1.7E-56 T 14-10-2018 HL41_01960 2daddccad49dbd0d0fe529916777c212 180 Hamap MF_00109 Shikimate kinase [aroK]. 1 171 26.791 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 HL41_01960 2daddccad49dbd0d0fe529916777c212 180 PRINTS PR01100 Shikimate kinase family signature 28 41 1.8E-19 T 14-10-2018 HL41_01960 2daddccad49dbd0d0fe529916777c212 180 PRINTS PR01100 Shikimate kinase family signature 56 64 1.8E-19 T 14-10-2018 HL41_01960 2daddccad49dbd0d0fe529916777c212 180 PRINTS PR01100 Shikimate kinase family signature 4 19 1.8E-19 T 14-10-2018 HL41_01960 2daddccad49dbd0d0fe529916777c212 180 PRINTS PR01100 Shikimate kinase family signature 74 83 1.8E-19 T 14-10-2018 HL41_01960 2daddccad49dbd0d0fe529916777c212 180 PRINTS PR01100 Shikimate kinase family signature 95 112 1.8E-19 T 14-10-2018 HL41_01960 2daddccad49dbd0d0fe529916777c212 180 SUPERFAMILY SSF52540 3 170 3.03E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01960 2daddccad49dbd0d0fe529916777c212 180 ProSitePatterns PS01128 Shikimate kinase signature. 57 82 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 HL41_01960 2daddccad49dbd0d0fe529916777c212 180 Gene3D G3DSA:3.40.50.300 1 178 3.0E-54 T 14-10-2018 HL41_01960 2daddccad49dbd0d0fe529916777c212 180 Pfam PF01202 Shikimate kinase 11 171 1.3E-45 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 2 281 1.2E-148 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 Gene3D G3DSA:3.30.930.10 1 204 1.7E-111 T 14-10-2018 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 SUPERFAMILY SSF55681 1 277 1.22E-128 T 14-10-2018 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 1.4E-65 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 1.4E-65 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 1.4E-65 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 1.4E-65 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 1.4E-65 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 1.4E-65 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 Gene3D G3DSA:1.20.58.180 205 284 2.9E-28 T 14-10-2018 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 59.036 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00865 7136daef61727a83c1825e668c8bcfdc 284 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 278 1.8E-149 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HL41_00870 26de078adeb3dcbfc86a79a123a481f6 347 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 6 336 7.5E-129 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_00870 26de078adeb3dcbfc86a79a123a481f6 347 SUPERFAMILY SSF55326 7 169 2.24E-47 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_00870 26de078adeb3dcbfc86a79a123a481f6 347 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 163 1.8E-16 T 14-10-2018 IPR016188 PurM-like, N-terminal domain HL41_00870 26de078adeb3dcbfc86a79a123a481f6 347 Gene3D G3DSA:3.30.1330.10 3 169 2.5E-63 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_00870 26de078adeb3dcbfc86a79a123a481f6 347 SUPERFAMILY SSF56042 170 341 1.08E-55 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_00870 26de078adeb3dcbfc86a79a123a481f6 347 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 5 347 43.495 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_00870 26de078adeb3dcbfc86a79a123a481f6 347 Gene3D G3DSA:3.90.650.10 171 347 9.0E-66 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_00870 26de078adeb3dcbfc86a79a123a481f6 347 Pfam PF02769 AIR synthase related protein, C-terminal domain 176 343 4.0E-31 T 14-10-2018 IPR010918 PurM-like, C-terminal domain HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Gene3D G3DSA:3.40.1170.10 1 123 1.3E-44 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 SUPERFAMILY SSF52540 566 798 2.42E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 SUPERFAMILY SSF55271 7 115 2.49E-40 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 SUPERFAMILY SSF53150 123 276 1.16E-25 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Gene3D G3DSA:1.10.1420.10 384 502 4.1E-99 T 14-10-2018 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 SMART SM00534 608 794 2.3E-114 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Gene3D G3DSA:3.30.420.110 129 255 1.5E-13 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Pfam PF05190 MutS family domain IV 427 517 5.3E-29 T 14-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 10 852 3.3E-300 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 PIRSF PIRSF037677 3 851 6.7E-170 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Pfam PF00488 MutS domain V 611 797 3.8E-85 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Gene3D G3DSA:3.40.50.300 567 855 1.2E-105 T 14-10-2018 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 SUPERFAMILY SSF48334 263 564 1.44E-91 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Pfam PF05192 MutS domain III 265 558 5.3E-44 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 SMART SM00533 280 590 3.7E-111 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 689 705 - T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Gene3D G3DSA:1.10.1420.10 262 558 4.1E-99 T 14-10-2018 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 9 846 23.934 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Pfam PF05188 MutS domain II 130 248 7.8E-9 T 14-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HL41_06500 1fbb82d5992efa7bad93cc5026e59a36 855 Pfam PF01624 MutS domain I 10 120 4.7E-40 T 14-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 179 314 9.0E-49 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 SUPERFAMILY SSF69075 325 427 1.83E-22 T 14-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 PIRSF PIRSF000445 7 440 7.5E-155 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 12 164 5.0E-44 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 SUPERFAMILY SSF51735 169 323 5.12E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 9 427 9.0E-143 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 SUPERFAMILY SSF69742 8 166 7.85E-44 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 Gene3D G3DSA:3.40.50.720 169 321 1.5E-47 T 14-10-2018 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 329 426 8.2E-24 T 14-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 Gene3D G3DSA:3.30.460.30 7 166 1.9E-50 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 8 427 30.013 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HL41_06555 acf3a5e7309ac57b60ff6121dc0ee28e 470 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 107 130 - T 14-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HL41_06645 6063aa288e36c0f1527557c7f4e60a71 261 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 9 257 4.3E-59 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 HL41_06645 6063aa288e36c0f1527557c7f4e60a71 261 Gene3D G3DSA:1.10.8.10 2 67 2.5E-13 T 14-10-2018 HL41_06645 6063aa288e36c0f1527557c7f4e60a71 261 Gene3D G3DSA:3.40.50.150 68 261 1.5E-55 T 14-10-2018 HL41_06645 6063aa288e36c0f1527557c7f4e60a71 261 SUPERFAMILY SSF53335 6 257 2.57E-45 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_06645 6063aa288e36c0f1527557c7f4e60a71 261 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 260 35.55 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HL41_06645 6063aa288e36c0f1527557c7f4e60a71 261 Pfam PF05175 Methyltransferase small domain 79 172 8.6E-9 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 HL41_06645 6063aa288e36c0f1527557c7f4e60a71 261 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 12 256 2.0E-72 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HL41_06645 6063aa288e36c0f1527557c7f4e60a71 261 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 165 171 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HL41_04805 25814ee929ff639611f5c66110d9c70e 359 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 39 359 4.0E-125 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HL41_04805 25814ee929ff639611f5c66110d9c70e 359 Pfam PF00953 Glycosyl transferase family 4 99 282 3.8E-33 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 HL41_04805 25814ee929ff639611f5c66110d9c70e 359 ProSitePatterns PS01348 MraY family signature 2. 187 198 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HL41_04805 25814ee929ff639611f5c66110d9c70e 359 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 357 24.768 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 SMART SM00316 134 199 6.9E-4 T 14-10-2018 IPR022967 RNA-binding domain, S1 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 Pfam PF13184 NusA-like KH domain 229 306 4.8E-25 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 SUPERFAMILY SSF50249 133 198 6.48E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 Gene3D G3DSA:3.30.1480.10 2 129 3.6E-35 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 Gene3D G3DSA:3.30.300.20 288 420 1.2E-40 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 7 351 2.9E-115 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 Gene3D G3DSA:2.40.50.140 136 197 8.2E-18 T 14-10-2018 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 SUPERFAMILY SSF47794 361 417 2.04E-7 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 3 416 28.88 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 SMART SM00322 310 387 0.0016 T 14-10-2018 IPR004087 K Homology domain GO:0003676 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 SUPERFAMILY SSF54814 288 351 7.19E-17 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 SUPERFAMILY SSF54814 199 286 2.42E-25 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 Pfam PF08529 NusA N-terminal domain 5 125 2.4E-30 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 Gene3D G3DSA:3.30.300.20 198 286 8.1E-30 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta HL41_02050 224b3be6318d9dcb1988a60562d6db0e 421 SUPERFAMILY SSF69705 5 126 7.85E-33 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 HL41_00970 84e0c2cc3d32eee4f172a9bddfe90b9c 234 SMART SM00858 109 171 2.9E-7 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HL41_00970 84e0c2cc3d32eee4f172a9bddfe90b9c 234 Gene3D G3DSA:3.90.1210.10 109 174 5.4E-7 T 14-10-2018 HL41_00970 84e0c2cc3d32eee4f172a9bddfe90b9c 234 Pfam PF13144 Chaperone for flagella basal body P-ring formation 38 232 4.1E-41 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal HL41_00970 84e0c2cc3d32eee4f172a9bddfe90b9c 234 Gene3D G3DSA:2.30.30.760 175 234 1.0E-12 T 14-10-2018 HL41_00970 84e0c2cc3d32eee4f172a9bddfe90b9c 234 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 98 232 9.6E-37 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal HL41_01100 f7df19ca405667cc4df37c4dc324997a 142 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 134 3.8E-14 T 14-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain HL41_01100 f7df19ca405667cc4df37c4dc324997a 142 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 82 3.0E-21 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01100 f7df19ca405667cc4df37c4dc324997a 142 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 133 7.1E-33 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01100 f7df19ca405667cc4df37c4dc324997a 142 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 132 22.3 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01100 f7df19ca405667cc4df37c4dc324997a 142 Gene3D G3DSA:2.60.15.10 1 88 3.0E-30 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01100 f7df19ca405667cc4df37c4dc324997a 142 Gene3D G3DSA:1.20.5.440 89 135 2.8E-13 T 14-10-2018 HL41_01100 f7df19ca405667cc4df37c4dc324997a 142 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 82 3.1E-27 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01100 f7df19ca405667cc4df37c4dc324997a 142 SUPERFAMILY SSF51344 4 84 6.15E-23 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01100 f7df19ca405667cc4df37c4dc324997a 142 SUPERFAMILY SSF46604 87 135 6.28E-7 T 14-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00245 f99dfbc8043378dfe541212a91059374 400 Pfam PF00925 GTP cyclohydrolase II 208 372 3.6E-77 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 HL41_00245 f99dfbc8043378dfe541212a91059374 400 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 209 396 2.2E-80 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 HL41_00245 f99dfbc8043378dfe541212a91059374 400 Gene3D G3DSA:3.90.870.10 1 205 2.8E-92 T 14-10-2018 HL41_00245 f99dfbc8043378dfe541212a91059374 400 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 199 3.8E-78 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_00245 f99dfbc8043378dfe541212a91059374 400 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 204 398 41.922 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 HL41_00245 f99dfbc8043378dfe541212a91059374 400 PIRSF PIRSF001259 2 399 6.8E-183 T 14-10-2018 HL41_00245 f99dfbc8043378dfe541212a91059374 400 SUPERFAMILY SSF142695 204 375 4.58E-74 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 HL41_00245 f99dfbc8043378dfe541212a91059374 400 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 4.1E-87 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_00245 f99dfbc8043378dfe541212a91059374 400 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 39.882 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_00245 f99dfbc8043378dfe541212a91059374 400 Gene3D G3DSA:3.40.50.10990 206 375 1.7E-77 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 HL41_00245 f99dfbc8043378dfe541212a91059374 400 SUPERFAMILY SSF55821 4 206 3.66E-88 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily HL41_00245 f99dfbc8043378dfe541212a91059374 400 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 2 394 55.572 T 14-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 HL41_03505 417c2ebf7da89161ee2ca72f340cfb78 218 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 203 3.7E-59 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 HL41_03505 417c2ebf7da89161ee2ca72f340cfb78 218 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 HL41_03505 417c2ebf7da89161ee2ca72f340cfb78 218 ProSitePatterns PS00958 Transaldolase active site. 81 98 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 HL41_03505 417c2ebf7da89161ee2ca72f340cfb78 218 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 1.5E-87 T 14-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HL41_03505 417c2ebf7da89161ee2ca72f340cfb78 218 Hamap MF_00494 Probable transaldolase [tal]. 1 215 42.918 T 14-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HL41_03505 417c2ebf7da89161ee2ca72f340cfb78 218 Gene3D G3DSA:3.20.20.70 1 216 3.3E-89 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_03505 417c2ebf7da89161ee2ca72f340cfb78 218 SUPERFAMILY SSF51569 1 213 5.76E-76 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 SUPERFAMILY SSF82866 299 499 4.71E-50 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 Gene3D G3DSA:3.30.70.1430 566 667 0.0 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 3.2E-89 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 3.2E-89 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 3.2E-89 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 3.2E-89 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 3.2E-89 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 3.2E-89 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 3.2E-89 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 3.2E-89 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 3.2E-89 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 Gene3D G3DSA:3.30.70.1320 134 334 0.0 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 SUPERFAMILY SSF82693 138 332 2.49E-18 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 Gene3D G3DSA:3.30.70.1430 39 816 0.0 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 Gene3D G3DSA:3.30.2090.10 720 808 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 Gene3D G3DSA:1.20.1640.10 9 511 0.0 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 SUPERFAMILY SSF82693 40 132 8.63E-26 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1030 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 SUPERFAMILY SSF82693 673 856 1.91E-25 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 SUPERFAMILY SSF82714 184 274 1.44E-19 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 SUPERFAMILY SSF82714 721 805 3.14E-17 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 SUPERFAMILY SSF82866 830 1025 3.53E-45 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 Gene3D G3DSA:1.20.1640.10 512 1022 0.0 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 Gene3D G3DSA:3.30.2090.10 180 277 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 Pfam PF00873 AcrB/AcrD/AcrF family 2 1025 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 Gene3D G3DSA:3.30.70.1440 668 865 0.0 T 14-10-2018 HL41_01770 b309b3c6809d30198878586a8aed11f0 1039 SUPERFAMILY SSF82693 564 670 2.72E-23 T 14-10-2018 HL41_02565 c9464fb0ac50684c60218daa9f1d6118 123 SMART SM00448 2 116 2.0E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_02565 c9464fb0ac50684c60218daa9f1d6118 123 Gene3D G3DSA:3.40.50.12740 2 122 8.0E-38 T 14-10-2018 HL41_02565 c9464fb0ac50684c60218daa9f1d6118 123 SUPERFAMILY SSF52172 1 121 2.56E-37 T 14-10-2018 IPR011006 CheY-like superfamily HL41_02565 c9464fb0ac50684c60218daa9f1d6118 123 Pfam PF00072 Response regulator receiver domain 5 116 1.4E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_06470 29e63672c449863048611116d3f5cd47 325 SUPERFAMILY SSF51905 8 322 1.48E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_06470 29e63672c449863048611116d3f5cd47 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 6.9E-17 T 14-10-2018 HL41_06470 29e63672c449863048611116d3f5cd47 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 6.9E-17 T 14-10-2018 HL41_06470 29e63672c449863048611116d3f5cd47 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 6.9E-17 T 14-10-2018 HL41_06470 29e63672c449863048611116d3f5cd47 325 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 294 1.4E-49 T 14-10-2018 HL41_06470 29e63672c449863048611116d3f5cd47 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_06470 29e63672c449863048611116d3f5cd47 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 217 233 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_06470 29e63672c449863048611116d3f5cd47 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_06470 29e63672c449863048611116d3f5cd47 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 134 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_06470 29e63672c449863048611116d3f5cd47 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_06470 29e63672c449863048611116d3f5cd47 325 Gene3D G3DSA:3.50.50.60 10 299 5.6E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_06470 29e63672c449863048611116d3f5cd47 325 Gene3D G3DSA:3.50.50.60 138 255 5.6E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_00240 1891b47b77fffb856030d61b793abdd3 429 Gene3D G3DSA:1.10.287.40 1 106 9.4E-28 T 14-10-2018 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 423 43.234 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 PIRSF PIRSF001529 1 427 1.4E-189 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 SUPERFAMILY SSF55681 118 420 1.74E-101 T 14-10-2018 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 418 2.0E-176 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 SUPERFAMILY SSF46589 1 114 2.46E-30 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 PRINTS PR00981 Seryl-tRNA synthetase signature 352 368 4.4E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 PRINTS PR00981 Seryl-tRNA synthetase signature 265 277 4.4E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 PRINTS PR00981 Seryl-tRNA synthetase signature 334 350 4.4E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 PRINTS PR00981 Seryl-tRNA synthetase signature 277 290 4.4E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 PRINTS PR00981 Seryl-tRNA synthetase signature 317 330 4.4E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 Gene3D G3DSA:3.30.930.10 107 429 1.2E-128 T 14-10-2018 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 225 401 7.9E-38 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_00240 1891b47b77fffb856030d61b793abdd3 429 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.4E-29 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 HL41_01670 697c2b70aefb576499c7fed1207af5d0 132 Pfam PF01814 Hemerythrin HHE cation binding domain 13 121 5.4E-11 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 HL41_01670 697c2b70aefb576499c7fed1207af5d0 132 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 125 1.5E-31 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HL41_01670 697c2b70aefb576499c7fed1207af5d0 132 Gene3D G3DSA:1.20.120.50 2 129 1.1E-35 T 14-10-2018 IPR035938 Hemerythrin-like superfamily HL41_01670 697c2b70aefb576499c7fed1207af5d0 132 SUPERFAMILY SSF47188 3 125 8.63E-32 T 14-10-2018 IPR035938 Hemerythrin-like superfamily HL41_01670 697c2b70aefb576499c7fed1207af5d0 132 ProSitePatterns PS00550 Hemerythrin family signature. 58 81 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 HL41_05890 18d8425d4cef6588001ae2bcc9befc61 77 Gene3D G3DSA:1.10.10.10 11 71 3.3E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_05890 18d8425d4cef6588001ae2bcc9befc61 77 Pfam PF13412 Winged helix-turn-helix DNA-binding 21 51 4.2E-5 T 14-10-2018 HL41_00435 6159537d9a6495248fe74f7f3e0bba1d 437 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 220 7.8E-61 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HL41_00435 6159537d9a6495248fe74f7f3e0bba1d 437 Gene3D G3DSA:3.40.1280.10 244 429 1.0E-69 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HL41_00435 6159537d9a6495248fe74f7f3e0bba1d 437 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 230 7.9E-92 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HL41_00435 6159537d9a6495248fe74f7f3e0bba1d 437 Pfam PF09936 SAM-dependent RNA methyltransferase 245 424 4.9E-68 T 14-10-2018 IPR019230 RNA methyltransferase domain HL41_00435 6159537d9a6495248fe74f7f3e0bba1d 437 Gene3D G3DSA:1.10.1270.20 172 243 5.5E-25 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HL41_00435 6159537d9a6495248fe74f7f3e0bba1d 437 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 296 97.778 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HL41_00435 6159537d9a6495248fe74f7f3e0bba1d 437 Gene3D G3DSA:3.40.1280.10 1 171 2.2E-72 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HL41_00435 6159537d9a6495248fe74f7f3e0bba1d 437 SUPERFAMILY SSF75217 1 242 4.58E-94 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases HL41_08900 c8ca63e03607a68bcf32ab1dc78e5934 319 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 200 212 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site HL41_08900 c8ca63e03607a68bcf32ab1dc78e5934 319 Gene3D G3DSA:1.10.600.10 1 319 4.0E-95 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily HL41_08900 c8ca63e03607a68bcf32ab1dc78e5934 319 Pfam PF00348 Polyprenyl synthetase 27 266 6.3E-67 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 HL41_08900 c8ca63e03607a68bcf32ab1dc78e5934 319 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 92 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site HL41_08900 c8ca63e03607a68bcf32ab1dc78e5934 319 SUPERFAMILY SSF48576 5 318 2.52E-87 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily HL41_03475 929e612b6dcb42eb68ce92b0a076b8c3 159 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 22 155 5.7E-17 T 14-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 HL41_03475 929e612b6dcb42eb68ce92b0a076b8c3 159 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 25 151 5.3E-13 T 14-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related HL41_08585 47c79ef690266a1c7624689b0748501a 809 SUPERFAMILY SSF50692 632 809 1.38E-47 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily HL41_08585 47c79ef690266a1c7624689b0748501a 809 Gene3D G3DSA:2.40.40.20 631 809 1.5E-73 T 14-10-2018 HL41_08585 47c79ef690266a1c7624689b0748501a 809 SUPERFAMILY SSF53706 1 641 4.58E-242 T 14-10-2018 HL41_08585 47c79ef690266a1c7624689b0748501a 809 Pfam PF00384 Molybdopterin oxidoreductase 2 376 9.4E-29 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08585 47c79ef690266a1c7624689b0748501a 809 Gene3D G3DSA:3.40.50.740 299 472 4.4E-70 T 14-10-2018 HL41_08585 47c79ef690266a1c7624689b0748501a 809 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 808 0.0 T 14-10-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 HL41_08585 47c79ef690266a1c7624689b0748501a 809 Gene3D G3DSA:3.40.228.10 548 630 2.0E-21 T 14-10-2018 HL41_08585 47c79ef690266a1c7624689b0748501a 809 Gene3D G3DSA:3.40.228.10 1 272 2.2E-83 T 14-10-2018 HL41_08585 47c79ef690266a1c7624689b0748501a 809 Pfam PF01568 Molydopterin dinucleotide binding domain 685 794 2.2E-16 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 HL41_08280 0434e76b98553275cd2befab8398db75 323 Gene3D G3DSA:3.30.930.10 85 271 2.5E-53 T 14-10-2018 HL41_08280 0434e76b98553275cd2befab8398db75 323 Gene3D G3DSA:1.10.10.10 1 62 6.3E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_08280 0434e76b98553275cd2befab8398db75 323 SUPERFAMILY SSF55681 83 270 1.06E-46 T 14-10-2018 HL41_08280 0434e76b98553275cd2befab8398db75 323 SUPERFAMILY SSF50037 275 319 2.75E-5 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal HL41_08280 0434e76b98553275cd2befab8398db75 323 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 10 320 30.625 T 14-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 HL41_08280 0434e76b98553275cd2befab8398db75 323 Pfam PF08279 HTH domain 8 58 4.6E-15 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 HL41_08280 0434e76b98553275cd2befab8398db75 323 Pfam PF02237 Biotin protein ligase C terminal domain 273 319 2.3E-7 T 14-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HL41_08280 0434e76b98553275cd2befab8398db75 323 SUPERFAMILY SSF46785 9 58 1.32E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_08280 0434e76b98553275cd2befab8398db75 323 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 87 319 1.2E-60 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HL41_08280 0434e76b98553275cd2befab8398db75 323 Gene3D G3DSA:2.30.30.100 272 321 3.0E-19 T 14-10-2018 HL41_08280 0434e76b98553275cd2befab8398db75 323 Pfam PF03099 Biotin/lipoate A/B protein ligase family 89 216 5.6E-17 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 SMART SM01383 42 118 1.7E-47 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 1.0E-58 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 Gene3D G3DSA:4.10.950.10 197 273 2.0E-36 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 PIRSF PIRSF002158 12 274 1.7E-106 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 48.653 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 SUPERFAMILY SSF50104 126 272 4.45E-64 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 SMART SM01382 124 252 4.7E-95 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 Gene3D G3DSA:2.30.30.30 118 196 7.8E-36 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 SUPERFAMILY SSF50249 3 125 6.17E-52 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 Gene3D G3DSA:2.40.50.140 1 114 1.2E-48 T 14-10-2018 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 2.0E-135 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HL41_05430 0bfcaf66846a40526361cf814a6f420a 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 9.5E-33 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_04050 275ea6ec3f5b3df88b285a01be41cac9 127 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 51 104 1.0E-15 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 HL41_04050 275ea6ec3f5b3df88b285a01be41cac9 127 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 28 101 4.4E-32 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 HL41_04050 275ea6ec3f5b3df88b285a01be41cac9 127 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 2 105 28.983 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 HL41_04050 275ea6ec3f5b3df88b285a01be41cac9 127 Gene3D G3DSA:3.10.20.400 1 92 3.1E-36 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 HL41_04050 275ea6ec3f5b3df88b285a01be41cac9 127 SUPERFAMILY SSF141734 4 117 4.84E-45 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 HL41_02425 a334a2f90fd0e61d3fb64e8448c7949f 356 Gene3D G3DSA:1.20.272.10 209 354 7.4E-12 T 14-10-2018 HL41_02425 a334a2f90fd0e61d3fb64e8448c7949f 356 Gene3D G3DSA:1.10.8.60 141 204 4.5E-7 T 14-10-2018 HL41_02425 a334a2f90fd0e61d3fb64e8448c7949f 356 SUPERFAMILY SSF52540 14 203 2.02E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08670 f6987b4657a57a839a084c5c46922abd 186 Pfam PF12838 4Fe-4S dicluster domain 60 115 2.4E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_08670 f6987b4657a57a839a084c5c46922abd 186 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08670 f6987b4657a57a839a084c5c46922abd 186 SUPERFAMILY SSF54862 33 165 2.05E-25 T 14-10-2018 HL41_08670 f6987b4657a57a839a084c5c46922abd 186 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 7 145 28.366 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08670 f6987b4657a57a839a084c5c46922abd 186 Gene3D G3DSA:3.30.70.3270 33 173 5.5E-37 T 14-10-2018 HL41_08670 f6987b4657a57a839a084c5c46922abd 186 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 16 139 1.4E-39 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 Gene3D G3DSA:1.10.8.60 311 387 5.7E-27 T 14-10-2018 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 SUPERFAMILY SSF52540 139 382 1.15E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 Pfam PF02954 Bacterial regulatory protein, Fis family 414 451 3.4E-6 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 SMART SM00382 159 302 1.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 Gene3D G3DSA:3.40.50.2300 2 120 1.2E-31 T 14-10-2018 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 Gene3D G3DSA:3.40.50.300 124 310 2.9E-65 T 14-10-2018 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 Pfam PF00158 Sigma-54 interaction domain 140 305 2.4E-69 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 SUPERFAMILY SSF52172 2 183 2.56E-37 T 14-10-2018 IPR011006 CheY-like superfamily HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 163 176 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 434 454 3.9E-5 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 417 434 3.9E-5 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 Pfam PF00072 Response regulator receiver domain 4 112 1.7E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 SMART SM00448 2 113 3.6E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 SUPERFAMILY SSF46689 352 453 4.93E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_02290 142afa04c08e41e5d9220f3e439e495f 459 Gene3D G3DSA:1.10.10.60 399 455 3.0E-17 T 14-10-2018 HL41_04735 e00740a3315483886be13bf860fd77e6 387 Gene3D G3DSA:3.30.300.10 104 374 2.6E-171 T 14-10-2018 HL41_04735 e00740a3315483886be13bf860fd77e6 387 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 233 372 9.6E-64 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 SUPERFAMILY SSF55973 111 232 7.85E-50 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 259 267 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 SUPERFAMILY SSF55973 5 112 1.81E-47 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 382 7.7E-181 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 Gene3D G3DSA:3.30.300.10 13 270 2.6E-171 T 14-10-2018 HL41_04735 e00740a3315483886be13bf860fd77e6 387 PIRSF PIRSF000497 1 384 2.0E-171 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 231 1.1E-45 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 383 56.029 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 SUPERFAMILY SSF55973 233 384 6.67E-65 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_04735 e00740a3315483886be13bf860fd77e6 387 Gene3D G3DSA:3.30.300.10 7 233 2.6E-171 T 14-10-2018 HL41_04735 e00740a3315483886be13bf860fd77e6 387 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 103 1.4E-43 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HL41_01710 37b2dd649e5eded79631e5cf720e33ef 642 Gene3D G3DSA:3.55.50.30 166 282 3.2E-26 T 14-10-2018 HL41_01710 37b2dd649e5eded79631e5cf720e33ef 642 PRINTS PR00811 Bacterial general secretion pathway protein D signature 472 496 3.2E-14 T 14-10-2018 IPR001775 GspD/PilQ family HL41_01710 37b2dd649e5eded79631e5cf720e33ef 642 PRINTS PR00811 Bacterial general secretion pathway protein D signature 598 616 3.2E-14 T 14-10-2018 IPR001775 GspD/PilQ family HL41_01710 37b2dd649e5eded79631e5cf720e33ef 642 PRINTS PR00811 Bacterial general secretion pathway protein D signature 381 391 3.2E-14 T 14-10-2018 IPR001775 GspD/PilQ family HL41_01710 37b2dd649e5eded79631e5cf720e33ef 642 PRINTS PR00811 Bacterial general secretion pathway protein D signature 621 635 3.2E-14 T 14-10-2018 IPR001775 GspD/PilQ family HL41_01710 37b2dd649e5eded79631e5cf720e33ef 642 Pfam PF03958 Bacterial type II/III secretion system short domain 311 381 8.5E-10 T 14-10-2018 IPR005644 NolW-like HL41_01710 37b2dd649e5eded79631e5cf720e33ef 642 Gene3D G3DSA:3.30.1370.120 307 378 4.8E-10 T 14-10-2018 IPR038591 NolW-like superfamily HL41_01710 37b2dd649e5eded79631e5cf720e33ef 642 Pfam PF00263 Bacterial type II and III secretion system protein 476 632 2.8E-44 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 HL41_05560 86ec6322b47e10b59d490c3c8224c01b 185 Gene3D G3DSA:3.30.700.20 9 179 2.6E-64 T 14-10-2018 IPR027485 AMMECR1, N-terminal HL41_05560 86ec6322b47e10b59d490c3c8224c01b 185 SUPERFAMILY SSF143447 2 180 1.09E-61 T 14-10-2018 IPR036071 AMMECR1 domain superfamily HL41_05560 86ec6322b47e10b59d490c3c8224c01b 185 Gene3D G3DSA:3.30.1490.150 110 177 2.6E-64 T 14-10-2018 HL41_05560 86ec6322b47e10b59d490c3c8224c01b 185 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 2 181 5.5E-52 T 14-10-2018 IPR023473 AMMECR1 HL41_05560 86ec6322b47e10b59d490c3c8224c01b 185 Pfam PF01871 AMMECR1 11 177 5.5E-53 T 14-10-2018 IPR002733 AMMECR1 domain HL41_05560 86ec6322b47e10b59d490c3c8224c01b 185 Hamap MF_00645 Protein . 3 175 30.622 T 14-10-2018 IPR023472 Uncharacterised protein family MJ0810 HL41_05560 86ec6322b47e10b59d490c3c8224c01b 185 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 10 177 2.3E-59 T 14-10-2018 IPR027623 AmmeMemoRadiSam system protein A HL41_05535 86ec6322b47e10b59d490c3c8224c01b 185 Gene3D G3DSA:3.30.700.20 9 179 2.6E-64 T 14-10-2018 IPR027485 AMMECR1, N-terminal HL41_05535 86ec6322b47e10b59d490c3c8224c01b 185 SUPERFAMILY SSF143447 2 180 1.09E-61 T 14-10-2018 IPR036071 AMMECR1 domain superfamily HL41_05535 86ec6322b47e10b59d490c3c8224c01b 185 Gene3D G3DSA:3.30.1490.150 110 177 2.6E-64 T 14-10-2018 HL41_05535 86ec6322b47e10b59d490c3c8224c01b 185 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 2 181 5.5E-52 T 14-10-2018 IPR023473 AMMECR1 HL41_05535 86ec6322b47e10b59d490c3c8224c01b 185 Pfam PF01871 AMMECR1 11 177 5.5E-53 T 14-10-2018 IPR002733 AMMECR1 domain HL41_05535 86ec6322b47e10b59d490c3c8224c01b 185 Hamap MF_00645 Protein . 3 175 30.622 T 14-10-2018 IPR023472 Uncharacterised protein family MJ0810 HL41_05535 86ec6322b47e10b59d490c3c8224c01b 185 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 10 177 2.3E-59 T 14-10-2018 IPR027623 AmmeMemoRadiSam system protein A HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 354 373 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 PIRSF PIRSF000774 1 468 3.1E-123 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 7 50 2.4E-14 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 Pfam PF04552 Sigma-54, DNA binding domain 307 466 1.3E-59 T 14-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 465 4.0E-123 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 PRINTS PR00045 Sigma-54 factor signature 382 393 3.7E-25 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 PRINTS PR00045 Sigma-54 factor signature 441 459 3.7E-25 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 PRINTS PR00045 Sigma-54 factor signature 175 192 3.7E-25 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 PRINTS PR00045 Sigma-54 factor signature 366 378 3.7E-25 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 446 453 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 Pfam PF04963 Sigma-54 factor, core binding domain 103 289 1.3E-45 T 14-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 Gene3D G3DSA:1.10.10.60 406 465 4.1E-22 T 14-10-2018 HL41_02770 f9903e2d52c6dc5438e3a4f3e0bce992 470 Gene3D G3DSA:1.10.10.1330 109 231 2.6E-26 T 14-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily HL41_02560 9672cee2849acc5c85aae13d7f14df2d 350 Gene3D G3DSA:3.40.50.2300 1 140 4.4E-36 T 14-10-2018 HL41_02560 9672cee2849acc5c85aae13d7f14df2d 350 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 2 341 38.813 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HL41_02560 9672cee2849acc5c85aae13d7f14df2d 350 PIRSF PIRSF000876 1 345 2.4E-133 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HL41_02560 9672cee2849acc5c85aae13d7f14df2d 350 Pfam PF00072 Response regulator receiver domain 4 112 3.1E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_02560 9672cee2849acc5c85aae13d7f14df2d 350 SUPERFAMILY SSF52738 152 340 9.68E-68 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal HL41_02560 9672cee2849acc5c85aae13d7f14df2d 350 SUPERFAMILY SSF52172 1 114 5.41E-32 T 14-10-2018 IPR011006 CheY-like superfamily HL41_02560 9672cee2849acc5c85aae13d7f14df2d 350 SMART SM00448 2 116 3.6E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_02560 9672cee2849acc5c85aae13d7f14df2d 350 Pfam PF01339 CheB methylesterase 158 336 2.0E-63 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HL41_02560 9672cee2849acc5c85aae13d7f14df2d 350 Gene3D G3DSA:3.40.50.180 150 340 2.6E-74 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00101 Aspartate carbamoyltransferase signature 228 237 5.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00101 Aspartate carbamoyltransferase signature 44 66 5.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00101 Aspartate carbamoyltransferase signature 269 274 5.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00101 Aspartate carbamoyltransferase signature 82 91 5.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00101 Aspartate carbamoyltransferase signature 137 154 5.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00101 Aspartate carbamoyltransferase signature 293 307 5.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 312 2.4E-90 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 SUPERFAMILY SSF53671 6 313 6.94E-92 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 277 300 5.4E-17 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 5.4E-17 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 54 73 5.4E-17 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 5.4E-17 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 54 61 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 309 2.0E-22 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 Gene3D G3DSA:3.40.50.1370 12 307 1.6E-88 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 Gene3D G3DSA:3.40.50.1370 138 291 1.6E-88 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 314 38.704 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HL41_07455 dfa333ea5b8ee539e40315364d9f1228 322 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 9 151 3.4E-41 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HL41_06955 d88171acbded93f0d2f2ba799f850800 163 Pfam PF07352 Bacteriophage Mu Gam like protein 17 154 3.0E-18 T 14-10-2018 IPR009951 Host-nuclease inhibitor protein Gam GO:0003690|GO:0042262 HL41_06955 d88171acbded93f0d2f2ba799f850800 163 SUPERFAMILY SSF161266 25 155 9.68E-18 T 14-10-2018 HL41_00150 0510c54665440d22ca0c738a2b1b9dba 380 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 352 5.9E-76 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 HL41_00150 0510c54665440d22ca0c738a2b1b9dba 380 Gene3D G3DSA:3.80.30.20 4 297 1.4E-85 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HL41_00150 0510c54665440d22ca0c738a2b1b9dba 380 SUPERFAMILY SSF102114 6 375 4.71E-90 T 14-10-2018 HL41_00150 0510c54665440d22ca0c738a2b1b9dba 380 Pfam PF04055 Radical SAM superfamily 11 184 1.7E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_00150 0510c54665440d22ca0c738a2b1b9dba 380 SMART SM00729 5 224 2.4E-35 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_00150 0510c54665440d22ca0c738a2b1b9dba 380 Pfam PF06969 HemN C-terminal domain 303 362 2.5E-10 T 14-10-2018 IPR010723 HemN, C-terminal HL41_05610 14aea8cd0db09517efa30bb59e47866b 194 SUPERFAMILY SSF54211 3 88 1.77E-27 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_05610 14aea8cd0db09517efa30bb59e47866b 194 Gene3D G3DSA:3.30.230.40 92 194 4.3E-35 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 HL41_05610 14aea8cd0db09517efa30bb59e47866b 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 63 76 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HL41_05610 14aea8cd0db09517efa30bb59e47866b 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 38.087 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HL41_05610 14aea8cd0db09517efa30bb59e47866b 194 SUPERFAMILY SSF54211 90 180 2.58E-32 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_05610 14aea8cd0db09517efa30bb59e47866b 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 33 175 4.9E-61 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HL41_05610 14aea8cd0db09517efa30bb59e47866b 194 Gene3D G3DSA:3.30.230.40 1 91 6.3E-31 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 HL41_05610 14aea8cd0db09517efa30bb59e47866b 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 SUPERFAMILY SSF64288 64 243 5.97E-30 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 SUPERFAMILY SSF46785 6 79 1.7E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 Pfam PF07702 UTRA domain 103 234 1.6E-20 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 Gene3D G3DSA:3.40.1410.10 96 238 1.5E-24 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 8.3E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 Gene3D G3DSA:1.10.10.10 12 80 3.8E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 SMART SM00866 97 236 3.8E-12 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HL41_08250 af43e02e108ca83e2312f3958cf9609b 245 SMART SM00345 17 76 1.4E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HL41_04250 ab7cc46bfc4de8fddeecc38b889e1c20 465 Pfam PF10996 Beta-Casp domain 253 376 3.9E-21 T 14-10-2018 IPR022712 Beta-Casp domain HL41_04250 ab7cc46bfc4de8fddeecc38b889e1c20 465 Gene3D G3DSA:3.60.15.10 8 436 6.5E-141 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_04250 ab7cc46bfc4de8fddeecc38b889e1c20 465 Pfam PF00753 Metallo-beta-lactamase superfamily 12 77 2.3E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_04250 ab7cc46bfc4de8fddeecc38b889e1c20 465 Gene3D G3DSA:3.40.50.10890 221 403 6.5E-141 T 14-10-2018 HL41_04250 ab7cc46bfc4de8fddeecc38b889e1c20 465 SMART SM00849 15 237 1.5E-15 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_04250 ab7cc46bfc4de8fddeecc38b889e1c20 465 SUPERFAMILY SSF56281 3 464 5.33E-125 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_04250 ab7cc46bfc4de8fddeecc38b889e1c20 465 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 391 455 2.7E-13 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HL41_04250 ab7cc46bfc4de8fddeecc38b889e1c20 465 SMART SM01027 253 377 1.3E-49 T 14-10-2018 IPR022712 Beta-Casp domain HL41_07365 f6eb475dfafeef097696497baecbe595 367 Pfam PF00361 Proton-conducting membrane transporter 57 318 1.2E-25 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_01330 aee3c357b43d76862a0d52a28cb44d98 208 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 205 5.2E-67 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 HL41_01330 aee3c357b43d76862a0d52a28cb44d98 208 PIRSF PIRSF000495 1 208 1.4E-70 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 HL41_01330 aee3c357b43d76862a0d52a28cb44d98 208 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 206 34.843 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 HL41_01330 aee3c357b43d76862a0d52a28cb44d98 208 Pfam PF00117 Glutamine amidotransferase class-I 6 202 1.4E-22 T 14-10-2018 IPR017926 Glutamine amidotransferase HL41_01330 aee3c357b43d76862a0d52a28cb44d98 208 SUPERFAMILY SSF52317 2 206 5.73E-54 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_01330 aee3c357b43d76862a0d52a28cb44d98 208 Gene3D G3DSA:3.40.50.880 1 207 2.7E-71 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_04945 511086c1d60dadc7ce052957345ebfe8 387 SUPERFAMILY SSF53383 6 363 1.5E-99 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_04945 511086c1d60dadc7ce052957345ebfe8 387 PIRSF PIRSF000524 1 384 1.4E-133 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 HL41_04945 511086c1d60dadc7ce052957345ebfe8 387 Pfam PF00266 Aminotransferase class-V 8 329 2.1E-42 T 14-10-2018 IPR000192 Aminotransferase class V domain HL41_04945 511086c1d60dadc7ce052957345ebfe8 387 Gene3D G3DSA:3.90.1150.10 13 372 1.0E-132 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_04945 511086c1d60dadc7ce052957345ebfe8 387 Gene3D G3DSA:3.40.640.10 18 260 1.0E-132 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_04945 511086c1d60dadc7ce052957345ebfe8 387 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 184 204 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HL41_09180 2dea95164166b3740a19c15295d1a212 271 PIRSF PIRSF000193 1 269 2.5E-80 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HL41_09180 2dea95164166b3740a19c15295d1a212 271 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 266 1.0E-83 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HL41_09180 2dea95164166b3740a19c15295d1a212 271 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 266 25.698 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HL41_09180 2dea95164166b3740a19c15295d1a212 271 SUPERFAMILY SSF48179 162 269 1.24E-32 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HL41_09180 2dea95164166b3740a19c15295d1a212 271 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 9.6E-36 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HL41_09180 2dea95164166b3740a19c15295d1a212 271 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 99 9.2E-19 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal HL41_09180 2dea95164166b3740a19c15295d1a212 271 Gene3D G3DSA:1.10.3730.10 165 271 1.3E-36 T 14-10-2018 HL41_09180 2dea95164166b3740a19c15295d1a212 271 SUPERFAMILY SSF51735 3 160 5.41E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_09180 2dea95164166b3740a19c15295d1a212 271 Gene3D G3DSA:3.40.50.720 1 164 5.6E-49 T 14-10-2018 HL41_07605 c6aad0295387c65097aed2edda3be6be 270 SUPERFAMILY SSF55315 2 103 1.65E-17 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like HL41_07605 c6aad0295387c65097aed2edda3be6be 270 SUPERFAMILY SSF75217 94 265 6.08E-45 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases HL41_07605 c6aad0295387c65097aed2edda3be6be 270 Pfam PF00588 SpoU rRNA Methylase family 119 258 2.9E-39 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HL41_07605 c6aad0295387c65097aed2edda3be6be 270 SMART SM00967 31 106 1.7E-9 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HL41_07605 c6aad0295387c65097aed2edda3be6be 270 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 102 5.6E-9 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HL41_07605 c6aad0295387c65097aed2edda3be6be 270 Gene3D G3DSA:3.30.1330.30 3 103 1.2E-17 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like HL41_07605 c6aad0295387c65097aed2edda3be6be 270 Gene3D G3DSA:3.40.1280.10 112 268 7.7E-49 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HL41_06420 82fa2404b8ea4a2c37735017ef45a9d9 328 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 301 9.1E-86 T 14-10-2018 IPR016040 NAD(P)-binding domain HL41_06420 82fa2404b8ea4a2c37735017ef45a9d9 328 SUPERFAMILY SSF51735 2 315 1.85E-100 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_06420 82fa2404b8ea4a2c37735017ef45a9d9 328 Gene3D G3DSA:3.40.50.720 2 300 1.7E-123 T 14-10-2018 HL41_06420 82fa2404b8ea4a2c37735017ef45a9d9 328 Gene3D G3DSA:3.90.25.10 187 308 1.7E-123 T 14-10-2018 HL41_06420 82fa2404b8ea4a2c37735017ef45a9d9 328 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 313 3.0E-132 T 14-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 HL41_03995 50bd3a9cda9c6fce64aae087f66df834 389 Hamap MF_02040 Iron-sulfur cluster carrier protein. 19 270 36.313 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein HL41_03995 50bd3a9cda9c6fce64aae087f66df834 389 Gene3D G3DSA:3.40.50.300 10 268 1.0E-83 T 14-10-2018 HL41_03995 50bd3a9cda9c6fce64aae087f66df834 389 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 23 269 2.9E-97 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 HL41_03995 50bd3a9cda9c6fce64aae087f66df834 389 SUPERFAMILY SSF53146 286 385 2.35E-6 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily HL41_03995 50bd3a9cda9c6fce64aae087f66df834 389 Gene3D G3DSA:3.30.420.130 283 389 6.2E-8 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily HL41_03995 50bd3a9cda9c6fce64aae087f66df834 389 ProSitePatterns PS01215 Mrp family signature. 133 149 - T 14-10-2018 IPR000808 Mrp, conserved site GO:0005524 HL41_03995 50bd3a9cda9c6fce64aae087f66df834 389 SUPERFAMILY SSF52540 13 254 6.38E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 Gene3D G3DSA:2.20.25.90 37 99 1.8E-26 T 14-10-2018 HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 Pfam PF01568 Molydopterin dinucleotide binding domain 607 720 2.9E-18 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 SMART SM00926 40 94 8.2E-16 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 Pfam PF00384 Molybdopterin oxidoreductase 97 515 2.3E-67 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 SUPERFAMILY SSF50692 570 732 7.84E-32 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 43 93 1.1E-13 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 Gene3D G3DSA:2.40.40.20 593 732 1.2E-58 T 14-10-2018 HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 Gene3D G3DSA:3.30.2070.10 474 560 1.1E-160 T 14-10-2018 HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 Gene3D G3DSA:3.40.228.10 172 586 1.1E-160 T 14-10-2018 HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 Gene3D G3DSA:3.40.50.740 108 521 1.1E-160 T 14-10-2018 HL41_04470 bbdf4388b8fe1a5fc11d56cb1b6bd9ea 732 SUPERFAMILY SSF53706 43 601 2.09E-160 T 14-10-2018 HL41_02530 0788d18c1f9ac3b6d287797d7dd4aadf 284 SUPERFAMILY SSF51735 1 159 1.32E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_02530 0788d18c1f9ac3b6d287797d7dd4aadf 284 PIRSF PIRSF000103 1 284 7.7E-70 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 HL41_02530 0788d18c1f9ac3b6d287797d7dd4aadf 284 SUPERFAMILY SSF48179 159 282 7.06E-32 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HL41_02530 0788d18c1f9ac3b6d287797d7dd4aadf 284 Gene3D G3DSA:3.40.50.720 1 158 4.4E-37 T 14-10-2018 HL41_02530 0788d18c1f9ac3b6d287797d7dd4aadf 284 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 161 280 2.9E-29 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 HL41_02530 0788d18c1f9ac3b6d287797d7dd4aadf 284 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 158 2.4E-32 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 HL41_02530 0788d18c1f9ac3b6d287797d7dd4aadf 284 Gene3D G3DSA:1.10.1040.10 159 284 4.6E-33 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HL41_00945 2ea971df88a5a4a7f2be0ec4b920e667 232 SUPERFAMILY SSF52540 7 227 1.03E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00945 2ea971df88a5a4a7f2be0ec4b920e667 232 SMART SM00382 35 222 5.4E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_00945 2ea971df88a5a4a7f2be0ec4b920e667 232 Gene3D G3DSA:3.40.50.300 5 230 4.7E-59 T 14-10-2018 HL41_00945 2ea971df88a5a4a7f2be0ec4b920e667 232 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_00945 2ea971df88a5a4a7f2be0ec4b920e667 232 Pfam PF00005 ABC transporter 26 173 1.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_05015 fa04f6e26c0159e8b2dcde85edc494ca 88 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 16.149 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_05015 fa04f6e26c0159e8b2dcde85edc494ca 88 SUPERFAMILY SSF63562 1 66 3.66E-18 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 HL41_05015 fa04f6e26c0159e8b2dcde85edc494ca 88 SMART SM01409 8 59 2.1E-11 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 HL41_05015 fa04f6e26c0159e8b2dcde85edc494ca 88 Gene3D G3DSA:3.90.940.10 1 85 3.4E-22 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 HL41_05015 fa04f6e26c0159e8b2dcde85edc494ca 88 Pfam PF01192 RNA polymerase Rpb6 8 59 1.9E-12 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 HL41_05015 fa04f6e26c0159e8b2dcde85edc494ca 88 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 57 5.2E-17 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_02025 c67252a4fb675673a2a05da51b7d22b7 256 Pfam PF03309 Type III pantothenate kinase 2 206 1.3E-51 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 HL41_02025 c67252a4fb675673a2a05da51b7d22b7 256 Gene3D G3DSA:3.30.420.40 92 256 5.4E-53 T 14-10-2018 HL41_02025 c67252a4fb675673a2a05da51b7d22b7 256 Gene3D G3DSA:3.30.420.40 1 89 7.3E-17 T 14-10-2018 HL41_02025 c67252a4fb675673a2a05da51b7d22b7 256 SUPERFAMILY SSF53067 123 252 3.24E-36 T 14-10-2018 HL41_02025 c67252a4fb675673a2a05da51b7d22b7 256 SUPERFAMILY SSF53067 1 121 2.38E-22 T 14-10-2018 HL41_02025 c67252a4fb675673a2a05da51b7d22b7 256 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 255 29.27 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 HL41_02025 c67252a4fb675673a2a05da51b7d22b7 256 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 248 4.5E-49 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 HL41_01050 ad5ac97dc6ca587b34baf672ad3ad96b 274 PIRSF PIRSF038471 1 272 7.0E-50 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 HL41_01050 ad5ac97dc6ca587b34baf672ad3ad96b 274 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 61 268 1.1E-28 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 HL41_01050 ad5ac97dc6ca587b34baf672ad3ad96b 274 Gene3D G3DSA:2.40.10.340 113 265 5.8E-36 T 14-10-2018 HL41_01050 ad5ac97dc6ca587b34baf672ad3ad96b 274 Pfam PF04085 rod shape-determining protein MreC 115 266 1.7E-35 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 HL41_01050 ad5ac97dc6ca587b34baf672ad3ad96b 274 Gene3D G3DSA:2.40.10.350 177 254 5.8E-36 T 14-10-2018 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 Hamap MF_00268 Protein RecA [recA]. 6 333 50.449 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 Gene3D G3DSA:3.30.250.10 272 347 3.2E-27 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 Pfam PF00154 recA bacterial DNA recombination protein 8 272 1.5E-132 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 Gene3D G3DSA:3.40.50.300 28 271 4.8E-81 T 14-10-2018 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 PRINTS PR00142 RecA protein signature 129 158 3.0E-82 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 PRINTS PR00142 RecA protein signature 214 242 3.0E-82 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 PRINTS PR00142 RecA protein signature 301 318 3.0E-82 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 PRINTS PR00142 RecA protein signature 167 196 3.0E-82 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 PRINTS PR00142 RecA protein signature 247 276 3.0E-82 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 PRINTS PR00142 RecA protein signature 95 124 3.0E-82 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 SUPERFAMILY SSF54752 272 330 1.11E-20 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 SUPERFAMILY SSF52540 7 271 2.48E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 SMART SM00382 59 232 7.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 328 2.0E-164 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HL41_06585 cf5ad4f141dd79a445822071b5b703e1 352 ProSitePatterns PS00321 recA signature. 217 225 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 HL41_09220 842cea57cdd53b66eeea808901c29447 487 SUPERFAMILY SSF56762 3 460 2.62E-100 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_09220 842cea57cdd53b66eeea808901c29447 487 Gene3D G3DSA:1.10.645.10 1 460 2.4E-89 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_09220 842cea57cdd53b66eeea808901c29447 487 Pfam PF00374 Nickel-dependent hydrogenase 40 117 7.4E-13 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 HL41_09220 842cea57cdd53b66eeea808901c29447 487 Pfam PF00374 Nickel-dependent hydrogenase 145 460 1.7E-12 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 HL41_09165 709e221a8357a3cb46f0d863608a6538 290 SUPERFAMILY SSF118352 227 285 1.83E-15 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HL41_09165 709e221a8357a3cb46f0d863608a6538 290 Gene3D G3DSA:3.55.30.10 1 229 2.7E-79 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HL41_09165 709e221a8357a3cb46f0d863608a6538 290 Pfam PF01430 Hsp33 protein 3 274 2.4E-78 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HL41_09165 709e221a8357a3cb46f0d863608a6538 290 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 286 34.027 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HL41_09165 709e221a8357a3cb46f0d863608a6538 290 SUPERFAMILY SSF64397 3 236 6.93E-65 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HL41_09165 709e221a8357a3cb46f0d863608a6538 290 Gene3D G3DSA:3.90.1280.10 230 287 3.1E-16 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HL41_09165 709e221a8357a3cb46f0d863608a6538 290 PIRSF PIRSF005261 1 286 5.9E-70 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HL41_08505 a2f58fced05be7dbe7b6173e026c44af 319 Pfam PF00294 pfkB family carbohydrate kinase 62 306 7.8E-35 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB HL41_08505 a2f58fced05be7dbe7b6173e026c44af 319 Gene3D G3DSA:3.40.1190.20 1 316 2.5E-47 T 14-10-2018 IPR029056 Ribokinase-like HL41_08505 a2f58fced05be7dbe7b6173e026c44af 319 SUPERFAMILY SSF53613 1 303 2.96E-43 T 14-10-2018 IPR029056 Ribokinase-like HL41_08525 dc5bc6d4a7f174ca5154fc35a9ac61f8 163 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 154 2.6E-32 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 HL41_08525 dc5bc6d4a7f174ca5154fc35a9ac61f8 163 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 156 1.2E-25 T 14-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 HL41_08525 dc5bc6d4a7f174ca5154fc35a9ac61f8 163 SUPERFAMILY SSF56300 1 158 1.27E-33 T 14-10-2018 HL41_08525 dc5bc6d4a7f174ca5154fc35a9ac61f8 163 Gene3D G3DSA:3.60.21.10 1 162 5.4E-41 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 SUPERFAMILY SSF52540 13 431 3.02E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 Gene3D G3DSA:3.40.50.300 480 732 8.7E-51 T 14-10-2018 HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 ProSitePatterns PS00211 ABC transporters family signature. 660 674 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 Gene3D G3DSA:1.20.1580.10 271 349 6.3E-40 T 14-10-2018 HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 Gene3D G3DSA:1.20.1580.10 90 248 8.4E-38 T 14-10-2018 HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 Gene3D G3DSA:3.30.190.20 130 235 8.4E-38 T 14-10-2018 HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 SUPERFAMILY SSF52540 483 742 2.21E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 ProSitePatterns PS00211 ABC transporters family signature. 349 363 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 Gene3D G3DSA:1.20.1580.10 545 700 8.7E-51 T 14-10-2018 HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 Gene3D G3DSA:3.40.50.300 9 89 8.4E-38 T 14-10-2018 HL41_01985 ee6a88ff4cf806413dbb0f708a03ec6b 769 Gene3D G3DSA:3.40.50.300 350 435 6.3E-40 T 14-10-2018 HL41_03550 6eecb821f7e04f6a75727fdbbdb7d691 314 PIRSF PIRSF005303 1 311 8.9E-81 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 HL41_03550 6eecb821f7e04f6a75727fdbbdb7d691 314 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 311 7.6E-76 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 HL41_03550 6eecb821f7e04f6a75727fdbbdb7d691 314 SUPERFAMILY SSF56042 142 296 4.04E-27 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_03550 6eecb821f7e04f6a75727fdbbdb7d691 314 Pfam PF00586 AIR synthase related protein, N-terminal domain 26 137 8.7E-17 T 14-10-2018 IPR016188 PurM-like, N-terminal domain HL41_03550 6eecb821f7e04f6a75727fdbbdb7d691 314 Pfam PF02769 AIR synthase related protein, C-terminal domain 148 293 6.9E-7 T 14-10-2018 IPR010918 PurM-like, C-terminal domain HL41_03550 6eecb821f7e04f6a75727fdbbdb7d691 314 Gene3D G3DSA:3.90.650.10 143 312 1.2E-44 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_03550 6eecb821f7e04f6a75727fdbbdb7d691 314 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 311 24.856 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 HL41_03550 6eecb821f7e04f6a75727fdbbdb7d691 314 SUPERFAMILY SSF55326 3 137 1.08E-26 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_03550 6eecb821f7e04f6a75727fdbbdb7d691 314 Gene3D G3DSA:3.30.1330.10 1 140 1.1E-32 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_02015 9f1c86ca13e520adb9b979274edec589 460 Pfam PF01946 Thi4 family 5 38 2.3E-6 T 14-10-2018 HL41_02015 9f1c86ca13e520adb9b979274edec589 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 413 435 9.6E-6 T 14-10-2018 HL41_02015 9f1c86ca13e520adb9b979274edec589 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.6E-6 T 14-10-2018 HL41_02015 9f1c86ca13e520adb9b979274edec589 460 SUPERFAMILY SSF51905 1 458 2.7E-31 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_02015 9f1c86ca13e520adb9b979274edec589 460 Gene3D G3DSA:3.50.50.60 1 92 2.2E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_02015 9f1c86ca13e520adb9b979274edec589 460 Gene3D G3DSA:3.50.50.60 122 232 1.4E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_02015 9f1c86ca13e520adb9b979274edec589 460 PIRSF PIRSF038984 123 460 1.6E-27 T 14-10-2018 IPR028348 FAD dependent protein HL41_02015 9f1c86ca13e520adb9b979274edec589 460 PIRSF PIRSF038984 1 91 9.7E-16 T 14-10-2018 IPR028348 FAD dependent protein HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 Gene3D G3DSA:2.10.230.10 95 157 7.9E-22 T 14-10-2018 HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 Pfam PF00684 DnaJ central domain 95 157 2.8E-10 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 Gene3D G3DSA:1.10.287.110 1 56 1.3E-7 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 Pfam PF01556 DnaJ C terminal domain 71 276 5.3E-17 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 SUPERFAMILY SSF49493 204 287 1.23E-10 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 SUPERFAMILY SSF46565 6 47 3.01E-7 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 SUPERFAMILY SSF57938 90 159 2.49E-14 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 Gene3D G3DSA:2.60.260.20 71 184 7.9E-22 T 14-10-2018 HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 SUPERFAMILY SSF49493 63 210 3.79E-6 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HL41_02550 175fbd02e7c7799defc7d6b8030af532 296 Gene3D G3DSA:2.60.260.20 199 296 8.7E-15 T 14-10-2018 HL41_01255 0ffa8035d734feac229b63f8cac236cd 166 TIGRFAM TIGR02084 leud: 3-isopropylmalate dehydratase, small subunit 6 160 6.8E-76 T 14-10-2018 IPR011824 Hydrolyase LeuD/DmdB, bacterial GO:0016836 KEGG: 00290+4.2.1.33 HL41_01255 0ffa8035d734feac229b63f8cac236cd 166 SUPERFAMILY SSF52016 2 163 5.69E-59 T 14-10-2018 HL41_01255 0ffa8035d734feac229b63f8cac236cd 166 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 4 164 41.046 T 14-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 HL41_01255 0ffa8035d734feac229b63f8cac236cd 166 Gene3D G3DSA:3.20.19.10 1 166 6.1E-65 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 HL41_01255 0ffa8035d734feac229b63f8cac236cd 166 Pfam PF00694 Aconitase C-terminal domain 28 108 3.9E-23 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 HL41_01255 0ffa8035d734feac229b63f8cac236cd 166 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 6 161 6.5E-69 T 14-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 HL41_01240 248a51eea2120a32a2e90c7950da2122 275 SUPERFAMILY SSF81345 10 266 1.11E-14 T 14-10-2018 IPR037294 ABC transporter, BtuC-like HL41_01240 248a51eea2120a32a2e90c7950da2122 275 Pfam PF00950 ABC 3 transport family 11 270 6.8E-35 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 HL41_08755 1562810dfaa2c81cbc064037da803cb0 252 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 35 245 1.7E-90 T 14-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 HL41_08755 1562810dfaa2c81cbc064037da803cb0 252 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 62 223 3.3E-31 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain HL41_08755 1562810dfaa2c81cbc064037da803cb0 252 PIRSF PIRSF005624 27 252 1.5E-95 T 14-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 HL41_08755 1562810dfaa2c81cbc064037da803cb0 252 SUPERFAMILY SSF52540 31 246 8.32E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08755 1562810dfaa2c81cbc064037da803cb0 252 Gene3D G3DSA:3.40.50.300 42 252 2.5E-66 T 14-10-2018 HL41_05135 8cbbdeb37406f34b7af2a8c374b805ed 565 SUPERFAMILY SSF56762 1 550 1.57E-176 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_05135 8cbbdeb37406f34b7af2a8c374b805ed 565 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 14-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 HL41_05135 8cbbdeb37406f34b7af2a8c374b805ed 565 Gene3D G3DSA:1.10.645.10 1 550 2.9E-231 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_05135 8cbbdeb37406f34b7af2a8c374b805ed 565 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 541 550 - T 14-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 HL41_05135 8cbbdeb37406f34b7af2a8c374b805ed 565 Pfam PF00374 Nickel-dependent hydrogenase 39 550 1.3E-220 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 HL41_07300 20067b664cfe7a30a4acad06737bf9e1 463 Gene3D G3DSA:3.30.70.2740 337 418 1.5E-13 T 14-10-2018 HL41_07300 20067b664cfe7a30a4acad06737bf9e1 463 Gene3D G3DSA:3.30.465.40 3 237 7.3E-77 T 14-10-2018 HL41_07300 20067b664cfe7a30a4acad06737bf9e1 463 SUPERFAMILY SSF55103 221 460 1.1E-68 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HL41_07300 20067b664cfe7a30a4acad06737bf9e1 463 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 458 1.2E-75 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HL41_07300 20067b664cfe7a30a4acad06737bf9e1 463 Gene3D G3DSA:1.10.45.10 419 459 1.5E-12 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HL41_07300 20067b664cfe7a30a4acad06737bf9e1 463 Pfam PF01565 FAD binding domain 42 180 2.3E-42 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HL41_07300 20067b664cfe7a30a4acad06737bf9e1 463 SUPERFAMILY SSF56176 5 218 2.29E-73 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HL41_05695 544e2e86df95795f571e0c6cefdc398d 432 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 159 389 5.1E-41 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HL41_05695 544e2e86df95795f571e0c6cefdc398d 432 Gene3D G3DSA:3.30.70.20 232 319 5.4E-109 T 14-10-2018 HL41_05695 544e2e86df95795f571e0c6cefdc398d 432 TIGRFAM TIGR02064 dsrA: sulfite reductase, dissimilatory-type alpha subunit 12 425 9.1E-168 T 14-10-2018 IPR011806 Sulphite reductase, dissimilatory-type alpha subunit GO:0018551|GO:0020037|GO:0051539|GO:0055114 HL41_05695 544e2e86df95795f571e0c6cefdc398d 432 SUPERFAMILY SSF56014 158 419 2.94E-56 T 14-10-2018 HL41_05695 544e2e86df95795f571e0c6cefdc398d 432 Gene3D G3DSA:3.30.413.10 158 409 5.4E-109 T 14-10-2018 HL41_05695 544e2e86df95795f571e0c6cefdc398d 432 Gene3D G3DSA:3.30.70.2500 57 157 4.1E-46 T 14-10-2018 HL41_05695 544e2e86df95795f571e0c6cefdc398d 432 SUPERFAMILY SSF55124 6 159 1.47E-62 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HL41_05695 544e2e86df95795f571e0c6cefdc398d 432 SUPERFAMILY SSF54862 221 314 3.87E-18 T 14-10-2018 HL41_01020 9ab4f68899679720f922b1722de4d933 460 Gene3D G3DSA:3.40.640.10 84 348 2.6E-174 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_01020 9ab4f68899679720f922b1722de4d933 460 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 455 212.12 T 14-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 HL41_01020 9ab4f68899679720f922b1722de4d933 460 Gene3D G3DSA:3.90.1150.110 3 442 2.6E-174 T 14-10-2018 HL41_01020 9ab4f68899679720f922b1722de4d933 460 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 2 450 1.3E-184 T 14-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 HL41_01020 9ab4f68899679720f922b1722de4d933 460 Pfam PF03841 L-seryl-tRNA selenium transferase 72 437 4.5E-165 T 14-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 HL41_01020 9ab4f68899679720f922b1722de4d933 460 SUPERFAMILY SSF53383 65 455 1.59E-50 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_03090 a29cad4f0284fa81b64d4864a954685a 739 SUPERFAMILY SSF52096 484 735 3.98E-47 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HL41_03090 a29cad4f0284fa81b64d4864a954685a 739 Gene3D G3DSA:3.90.226.10 480 730 4.9E-47 T 14-10-2018 HL41_03090 a29cad4f0284fa81b64d4864a954685a 739 SUPERFAMILY SSF52096 33 321 1.87E-46 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HL41_03090 a29cad4f0284fa81b64d4864a954685a 739 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 579 593 1.3E-8 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HL41_03090 a29cad4f0284fa81b64d4864a954685a 739 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 680 691 1.3E-8 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HL41_03090 a29cad4f0284fa81b64d4864a954685a 739 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 614 632 1.3E-8 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HL41_03090 a29cad4f0284fa81b64d4864a954685a 739 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 30 172 1.4E-27 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 HL41_08700 5b18a2787d9909134a374ab64de98f24 493 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 73 119 1.1E-6 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08700 5b18a2787d9909134a374ab64de98f24 493 Pfam PF00361 Proton-conducting membrane transporter 133 427 1.4E-53 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08700 5b18a2787d9909134a374ab64de98f24 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 80 105 1.5E-16 T 14-10-2018 HL41_08700 5b18a2787d9909134a374ab64de98f24 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 1.5E-16 T 14-10-2018 HL41_08700 5b18a2787d9909134a374ab64de98f24 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 1.5E-16 T 14-10-2018 HL41_08700 5b18a2787d9909134a374ab64de98f24 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 423 442 1.5E-16 T 14-10-2018 HL41_05480 e94d9bf8a7ed25b042cd78897fd7466b 459 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 60 214 7.8E-8 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 Pfam PF00338 Ribosomal protein S10p/S20e 8 102 4.7E-39 T 14-10-2018 IPR027486 Ribosomal protein S10 domain HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 PRINTS PR00971 Ribosomal protein S10 family signature 6 19 4.8E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 PRINTS PR00971 Ribosomal protein S10 family signature 41 56 4.8E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 PRINTS PR00971 Ribosomal protein S10 family signature 62 76 4.8E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 SUPERFAMILY SSF54999 6 103 8.37E-41 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 Gene3D G3DSA:3.30.70.600 2 103 4.6E-42 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 SMART SM01403 8 102 1.7E-59 T 14-10-2018 IPR027486 Ribosomal protein S10 domain HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 5 103 5.6E-47 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 30 45 - T 14-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05450 0b1194bb2d9e774cbbfa76d534d6fa1a 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 4 103 28.055 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_00740 5c320463066f4127bf01728faad6a45d 187 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 HL41_00740 5c320463066f4127bf01728faad6a45d 187 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 175 32.133 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HL41_00740 5c320463066f4127bf01728faad6a45d 187 SUPERFAMILY SSF53178 1 182 1.57E-58 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 HL41_00740 5c320463066f4127bf01728faad6a45d 187 Gene3D G3DSA:3.40.50.1470 1 185 1.9E-65 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 HL41_00740 5c320463066f4127bf01728faad6a45d 187 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 183 1.6E-54 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HL41_00740 5c320463066f4127bf01728faad6a45d 187 Pfam PF01195 Peptidyl-tRNA hydrolase 3 181 1.5E-55 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HL41_08960 6566bf9cfea35a4f2a0279eca8a0f6f9 56 Pfam PF00471 Ribosomal protein L33 9 55 2.1E-25 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08960 6566bf9cfea35a4f2a0279eca8a0f6f9 56 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_08960 6566bf9cfea35a4f2a0279eca8a0f6f9 56 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 19.287 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08960 6566bf9cfea35a4f2a0279eca8a0f6f9 56 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 3.5E-27 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08960 6566bf9cfea35a4f2a0279eca8a0f6f9 56 SUPERFAMILY SSF57829 4 55 2.81E-21 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 HL41_08960 6566bf9cfea35a4f2a0279eca8a0f6f9 56 Gene3D G3DSA:2.20.28.120 2 55 7.9E-26 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_06125 73e3a895b3bd7b8fe7a87c63aada33e9 409 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 134 409 9.3E-108 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06125 73e3a895b3bd7b8fe7a87c63aada33e9 409 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 10 409 46.606 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06125 73e3a895b3bd7b8fe7a87c63aada33e9 409 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 21 409 1.4E-155 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06125 73e3a895b3bd7b8fe7a87c63aada33e9 409 SUPERFAMILY SSF56762 30 409 6.02E-124 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06125 73e3a895b3bd7b8fe7a87c63aada33e9 409 Gene3D G3DSA:1.10.645.20 19 409 9.0E-156 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_00705 1ed711a81a72110d0b526c51078176db 269 SMART SM01232 131 221 5.6E-38 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 HL41_00705 1ed711a81a72110d0b526c51078176db 269 SUPERFAMILY SSF57716 217 268 3.09E-14 T 14-10-2018 HL41_00705 1ed711a81a72110d0b526c51078176db 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 116 1.2E-20 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 HL41_00705 1ed711a81a72110d0b526c51078176db 269 SUPERFAMILY SSF81624 2 137 5.76E-23 T 14-10-2018 IPR035937 MutM-like, N-terminal HL41_00705 1ed711a81a72110d0b526c51078176db 269 SUPERFAMILY SSF46946 131 218 5.63E-27 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 HL41_00705 1ed711a81a72110d0b526c51078176db 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 244 268 - T 14-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 HL41_00705 1ed711a81a72110d0b526c51078176db 269 Gene3D G3DSA:3.20.190.10 1 130 2.7E-26 T 14-10-2018 IPR035937 MutM-like, N-terminal HL41_00705 1ed711a81a72110d0b526c51078176db 269 SMART SM00898 2 117 3.6E-21 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 HL41_00705 1ed711a81a72110d0b526c51078176db 269 Gene3D G3DSA:1.10.8.50 134 269 4.2E-47 T 14-10-2018 HL41_00705 1ed711a81a72110d0b526c51078176db 269 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 268 5.7E-76 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 HL41_00705 1ed711a81a72110d0b526c51078176db 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 268 2.3E-5 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 HL41_00705 1ed711a81a72110d0b526c51078176db 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 138 218 2.3E-27 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 HL41_04610 5c03c19099d1e73bbd1ad5ba54b67747 75 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 34 3.7E-9 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_04610 5c03c19099d1e73bbd1ad5ba54b67747 75 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 36 65 3.7E-9 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_04610 5c03c19099d1e73bbd1ad5ba54b67747 75 SUPERFAMILY SSF58104 4 73 1.27E-23 T 14-10-2018 HL41_04610 5c03c19099d1e73bbd1ad5ba54b67747 75 Gene3D G3DSA:1.10.287.950 1 74 9.1E-25 T 14-10-2018 HL41_04610 5c03c19099d1e73bbd1ad5ba54b67747 75 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 4 73 1.4E-19 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 PIRSF PIRSF002144 1 96 3.0E-33 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.407 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 5.3E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 5.3E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 5.3E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 90 1.5E-45 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 SUPERFAMILY SSF54570 3 84 3.4E-36 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 Gene3D G3DSA:3.30.860.10 1 92 3.2E-41 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05425 ef863732aae65a6aa2053e411c04c5d2 96 Pfam PF00203 Ribosomal protein S19 3 83 9.0E-38 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_09105 641c1fed14065c009adddfae03964c90 336 SUPERFAMILY SSF52540 3 331 7.37E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_09105 641c1fed14065c009adddfae03964c90 336 Gene3D G3DSA:1.10.8.80 248 335 1.4E-27 T 14-10-2018 HL41_09105 641c1fed14065c009adddfae03964c90 336 Pfam PF01078 Magnesium chelatase, subunit ChlI 115 183 5.9E-6 T 14-10-2018 IPR000523 Magnesium chelatase ChlI domain HL41_09105 641c1fed14065c009adddfae03964c90 336 Gene3D G3DSA:3.40.50.300 1 203 6.7E-67 T 14-10-2018 HL41_09105 641c1fed14065c009adddfae03964c90 336 SMART SM00382 26 207 3.8E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_06200 2dec8b8f0828c066fd66c9f7ab277cf6 210 Gene3D G3DSA:3.90.550.10 1 209 4.5E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_06200 2dec8b8f0828c066fd66c9f7ab277cf6 210 SUPERFAMILY SSF53448 1 206 5.63E-20 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_06200 2dec8b8f0828c066fd66c9f7ab277cf6 210 Pfam PF12804 MobA-like NTP transferase domain 3 137 1.8E-18 T 14-10-2018 IPR025877 MobA-like NTP transferase HL41_04840 ee30e2d6586d93cbd192d4b26ad11063 286 Pfam PF00037 4Fe-4S binding domain 62 83 1.5E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_04840 ee30e2d6586d93cbd192d4b26ad11063 286 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 261 7.7E-18 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HL41_04840 ee30e2d6586d93cbd192d4b26ad11063 286 Gene3D G3DSA:3.30.70.20 65 109 3.0E-9 T 14-10-2018 HL41_04840 ee30e2d6586d93cbd192d4b26ad11063 286 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 94 105 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_04840 ee30e2d6586d93cbd192d4b26ad11063 286 SUPERFAMILY SSF52540 1 284 1.46E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04840 ee30e2d6586d93cbd192d4b26ad11063 286 SUPERFAMILY SSF54862 54 112 3.35E-11 T 14-10-2018 HL41_08260 8e65844945f500f01166ec8299daa93a 503 PRINTS PR00758 Arsenical pump membrane protein signature 465 489 2.3E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HL41_08260 8e65844945f500f01166ec8299daa93a 503 PRINTS PR00758 Arsenical pump membrane protein signature 350 374 2.3E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HL41_08260 8e65844945f500f01166ec8299daa93a 503 PRINTS PR00758 Arsenical pump membrane protein signature 396 418 2.3E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HL41_08260 8e65844945f500f01166ec8299daa93a 503 PRINTS PR00758 Arsenical pump membrane protein signature 163 187 2.3E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HL41_08260 8e65844945f500f01166ec8299daa93a 503 PIRSF PIRSF002457 16 499 2.0E-113 T 14-10-2018 IPR030676 Citrate carrier CitT-related HL41_08260 8e65844945f500f01166ec8299daa93a 503 Pfam PF00939 Sodium:sulfate symporter transmembrane region 63 498 2.1E-52 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 SMART SM00116 210 258 0.0019 T 14-10-2018 IPR000644 CBS domain HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 SMART SM00116 275 323 8.1E-4 T 14-10-2018 IPR000644 CBS domain HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 SUPERFAMILY SSF53697 11 319 6.9E-63 T 14-10-2018 HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 45 314 5.1E-103 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 Gene3D G3DSA:3.10.580.10 196 320 1.2E-43 T 14-10-2018 HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 Pfam PF00571 CBS domain 201 257 1.0E-5 T 14-10-2018 IPR000644 CBS domain HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 Pfam PF00571 CBS domain 268 320 6.7E-11 T 14-10-2018 IPR000644 CBS domain HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 Gene3D G3DSA:3.40.50.10490 2 195 1.1E-67 T 14-10-2018 HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 Pfam PF01380 SIS domain 41 171 1.0E-30 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HL41_09135 8d23095ee613f6aba74e0214ee6d51f7 328 PIRSF PIRSF004692 1 324 1.8E-131 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 HL41_01550 fc4805c958e268d2290d905e4660d751 658 SUPERFAMILY SSF56801 15 650 3.53E-185 T 14-10-2018 HL41_01550 fc4805c958e268d2290d905e4660d751 658 Gene3D G3DSA:3.40.50.12780 61 524 9.7E-110 T 14-10-2018 HL41_01550 fc4805c958e268d2290d905e4660d751 658 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 618 6.3E-26 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HL41_01550 fc4805c958e268d2290d905e4660d751 658 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 88 3.2E-19 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 HL41_01550 fc4805c958e268d2290d905e4660d751 658 Gene3D G3DSA:3.30.300.30 527 658 4.4E-30 T 14-10-2018 HL41_01550 fc4805c958e268d2290d905e4660d751 658 Pfam PF00501 AMP-binding enzyme 100 531 3.9E-96 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HL41_01550 fc4805c958e268d2290d905e4660d751 658 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 9 654 50.664 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 HL41_01550 fc4805c958e268d2290d905e4660d751 658 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 28 651 3.3E-292 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 HL41_01550 fc4805c958e268d2290d905e4660d751 658 ProSitePatterns PS00455 Putative AMP-binding domain signature. 270 281 - T 14-10-2018 IPR020845 AMP-binding, conserved site HL41_01715 40a60cb96bb75f573fc79b4a1d84711a 436 SUPERFAMILY SSF51905 4 365 1.1E-24 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_01715 40a60cb96bb75f573fc79b4a1d84711a 436 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 3 432 4.3E-202 T 14-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 HL41_01715 40a60cb96bb75f573fc79b4a1d84711a 436 Pfam PF01134 Glucose inhibited division protein A 4 366 1.7E-106 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 HL41_01715 40a60cb96bb75f573fc79b4a1d84711a 436 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 4 432 36.083 T 14-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 HL41_01715 40a60cb96bb75f573fc79b4a1d84711a 436 Gene3D G3DSA:3.50.50.60 290 436 6.4E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_01715 40a60cb96bb75f573fc79b4a1d84711a 436 Gene3D G3DSA:3.50.50.60 1 181 4.6E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_00210 cc661a7434281ae88a3e3058ebb6c216 161 SUPERFAMILY SSF46785 6 66 8.02E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_00210 cc661a7434281ae88a3e3058ebb6c216 161 Gene3D G3DSA:3.30.70.3460 30 160 1.2E-38 T 14-10-2018 HL41_03005 62c48819984abce5fe772ef4bbbb37f7 220 SUPERFAMILY SSF53335 13 214 2.76E-49 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_03005 62c48819984abce5fe772ef4bbbb37f7 220 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 139 154 - T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 HL41_03005 62c48819984abce5fe772ef4bbbb37f7 220 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 15 214 4.4E-65 T 14-10-2018 HL41_03005 62c48819984abce5fe772ef4bbbb37f7 220 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 15 215 6.3E-69 T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 HL41_03005 62c48819984abce5fe772ef4bbbb37f7 220 Gene3D G3DSA:3.40.50.150 3 220 9.5E-80 T 14-10-2018 HL41_03005 62c48819984abce5fe772ef4bbbb37f7 220 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 11 218 39.715 T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 Gene3D G3DSA:3.90.640.10 226 313 2.4E-164 T 14-10-2018 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 9 16 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 6 600 1.8E-297 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 Gene3D G3DSA:3.30.420.40 7 376 2.4E-164 T 14-10-2018 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 Pfam PF00012 Hsp70 protein 6 600 3.7E-269 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 Gene3D G3DSA:1.20.1270.10 521 604 3.3E-26 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 PRINTS PR00301 70kDa heat shock protein signature 199 209 2.7E-77 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 PRINTS PR00301 70kDa heat shock protein signature 5 18 2.7E-77 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 PRINTS PR00301 70kDa heat shock protein signature 385 404 2.7E-77 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 PRINTS PR00301 70kDa heat shock protein signature 466 482 2.7E-77 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 PRINTS PR00301 70kDa heat shock protein signature 56 64 2.7E-77 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 PRINTS PR00301 70kDa heat shock protein signature 140 160 2.7E-77 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 PRINTS PR00301 70kDa heat shock protein signature 331 347 2.7E-77 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 PRINTS PR00301 70kDa heat shock protein signature 33 45 2.7E-77 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 PRINTS PR00301 70kDa heat shock protein signature 362 382 2.7E-77 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 Gene3D G3DSA:2.60.34.10 380 520 1.2E-64 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 Gene3D G3DSA:3.30.420.40 182 363 2.4E-164 T 14-10-2018 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 SUPERFAMILY SSF53067 6 186 1.21E-67 T 14-10-2018 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 SUPERFAMILY SSF100934 531 598 8.63E-6 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 3 628 37.489 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 SUPERFAMILY SSF53067 188 379 3.15E-69 T 14-10-2018 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 334 348 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 HL41_01160 90f9c1ae844d8730beccff054995b0c2 629 SUPERFAMILY SSF100920 381 537 5.76E-64 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 HL41_01365 2e25314553075435da3d3c5875a0267c 203 SUPERFAMILY SSF109604 16 118 4.97E-13 T 14-10-2018 HL41_01365 2e25314553075435da3d3c5875a0267c 203 Pfam PF01966 HD domain 21 100 1.7E-6 T 14-10-2018 IPR006674 HD domain HL41_01365 2e25314553075435da3d3c5875a0267c 203 Gene3D G3DSA:1.10.3210.10 4 155 2.2E-10 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00096 Glutamine amidotransferase superfamily signature 171 184 7.5E-12 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 7.5E-12 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 7.5E-12 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 2.4E-6 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 2.4E-6 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 Gene3D G3DSA:3.40.50.880 1 190 7.2E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_07195 243b43e078b11d9a0212155236ccef44 217 Pfam PF00117 Glutamine amidotransferase class-I 6 182 6.0E-49 T 14-10-2018 IPR017926 Glutamine amidotransferase HL41_07195 243b43e078b11d9a0212155236ccef44 217 SUPERFAMILY SSF52317 1 187 7.45E-51 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_07195 243b43e078b11d9a0212155236ccef44 217 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 183 1.6E-70 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00097 Anthranilate synthase component II signature 4 18 2.6E-33 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00097 Anthranilate synthase component II signature 81 92 2.6E-33 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00097 Anthranilate synthase component II signature 54 63 2.6E-33 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00097 Anthranilate synthase component II signature 126 138 2.6E-33 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00097 Anthranilate synthase component II signature 106 114 2.6E-33 T 14-10-2018 HL41_07195 243b43e078b11d9a0212155236ccef44 217 PRINTS PR00097 Anthranilate synthase component II signature 171 184 2.6E-33 T 14-10-2018 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 SUPERFAMILY SSF55957 365 454 1.74E-25 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 Gene3D G3DSA:3.40.120.10 247 364 1.4E-42 T 14-10-2018 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 153 250 6.3E-22 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 Gene3D G3DSA:3.40.120.10 1 149 1.6E-51 T 14-10-2018 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 SUPERFAMILY SSF53738 254 362 5.89E-36 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 Gene3D G3DSA:3.30.310.50 367 455 7.5E-29 T 14-10-2018 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 Gene3D G3DSA:3.40.120.10 169 246 8.6E-27 T 14-10-2018 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 SUPERFAMILY SSF53738 4 145 1.32E-37 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 201 214 1.2E-17 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 167 186 1.2E-17 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 230 245 1.2E-17 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 1.2E-17 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 SUPERFAMILY SSF53738 151 252 2.12E-28 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 370 447 2.6E-11 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 138 1.4E-32 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_00255 b4e49e73f1caf18731a8ba327f498499 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 255 363 2.0E-27 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 SUPERFAMILY SSF56059 129 400 1.38E-106 T 14-10-2018 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 SMART SM00851 958 1045 4.1E-22 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain HL41_03105 53c824f386495fca037967ebb97f4d35 1084 SUPERFAMILY SSF52440 1 127 3.6E-50 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HL41_03105 53c824f386495fca037967ebb97f4d35 1084 SUPERFAMILY SSF56059 676 936 2.47E-104 T 14-10-2018 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1066 13.046 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1073 13.815 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 841 848 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Pfam PF02142 MGS-like domain 960 1045 2.2E-16 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain HL41_03105 53c824f386495fca037967ebb97f4d35 1084 SUPERFAMILY SSF48108 395 556 1.44E-51 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 SUPERFAMILY SSF52440 560 678 1.15E-50 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HL41_03105 53c824f386495fca037967ebb97f4d35 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 8.4E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 8.4E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 8.4E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 8.4E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 8.4E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 8.4E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 8.4E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 430 550 4.0E-43 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Gene3D G3DSA:1.10.1030.10 408 556 8.6E-49 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 712 726 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Gene3D G3DSA:3.40.50.20 1 116 8.6E-51 T 14-10-2018 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 677 878 1.6E-36 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 334 1.4E-70 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Gene3D G3DSA:3.30.470.20 119 402 5.1E-121 T 14-10-2018 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 SMART SM01096 427 550 4.4E-70 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Gene3D G3DSA:3.30.470.20 668 938 1.6E-118 T 14-10-2018 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 SUPERFAMILY SSF52335 938 1077 1.19E-35 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Gene3D G3DSA:3.40.50.20 557 665 1.6E-48 T 14-10-2018 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 Gene3D G3DSA:3.40.50.1380 939 1077 3.5E-39 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily HL41_03105 53c824f386495fca037967ebb97f4d35 1084 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HL41_03105 53c824f386495fca037967ebb97f4d35 1084 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1056 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_08020 fae467435245ea011bda4e2653343bac 1140 SUPERFAMILY SSF89550 4 261 8.24E-37 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HL41_08020 fae467435245ea011bda4e2653343bac 1140 Gene3D G3DSA:1.10.10.1600 439 515 5.8E-22 T 14-10-2018 HL41_08020 fae467435245ea011bda4e2653343bac 1140 Pfam PF02811 PHP domain 6 177 5.8E-54 T 14-10-2018 IPR004013 PHP domain GO:0003824 HL41_08020 fae467435245ea011bda4e2653343bac 1140 Gene3D G3DSA:3.20.20.140 2 276 9.9E-106 T 14-10-2018 HL41_08020 fae467435245ea011bda4e2653343bac 1140 Gene3D G3DSA:1.10.150.870 776 876 1.9E-5 T 14-10-2018 HL41_08020 fae467435245ea011bda4e2653343bac 1140 SMART SM00481 5 72 3.7E-28 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HL41_08020 fae467435245ea011bda4e2653343bac 1140 Pfam PF14579 Helix-hairpin-helix motif 803 888 2.2E-27 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HL41_08020 fae467435245ea011bda4e2653343bac 1140 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 298 728 4.4E-175 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HL41_08020 fae467435245ea011bda4e2653343bac 1140 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1014 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HL41_06710 8817725ad9c2a8d1b1697dff92ed9478 436 Pfam PF01964 Radical SAM ThiC family 7 423 9.8E-194 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 HL41_06710 8817725ad9c2a8d1b1697dff92ed9478 436 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 8 425 2.9E-187 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 HL41_06710 8817725ad9c2a8d1b1697dff92ed9478 436 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 428 87.104 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 HL41_06710 8817725ad9c2a8d1b1697dff92ed9478 436 Gene3D G3DSA:3.20.20.540 43 364 4.2E-148 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 HL41_00395 6bfc9c5d591a2b949ee515ace3aa6f9c 64 Pfam PF03966 Trm112p-like protein 10 46 8.1E-6 T 14-10-2018 IPR005651 Trm112-like HL41_00395 6bfc9c5d591a2b949ee515ace3aa6f9c 64 Gene3D G3DSA:2.20.25.10 12 63 1.1E-18 T 14-10-2018 HL41_00395 6bfc9c5d591a2b949ee515ace3aa6f9c 64 SUPERFAMILY SSF158997 9 61 1.03E-15 T 14-10-2018 HL41_02315 91bfc462c3692adca20c634269a078f4 399 SUPERFAMILY SSF56796 19 397 5.1E-97 T 14-10-2018 HL41_02315 91bfc462c3692adca20c634269a078f4 399 Gene3D G3DSA:1.20.1090.10 198 398 3.8E-43 T 14-10-2018 HL41_02315 91bfc462c3692adca20c634269a078f4 399 Pfam PF00465 Iron-containing alcohol dehydrogenase 21 375 8.7E-90 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 HL41_02315 91bfc462c3692adca20c634269a078f4 399 Gene3D G3DSA:3.40.50.1970 3 196 6.1E-46 T 14-10-2018 HL41_02575 162396dcc5f7b958c537aaf88e980478 113 Gene3D G3DSA:1.10.10.60 68 110 7.1E-6 T 14-10-2018 HL41_08220 bb7ee49ad2d7ba75cae009d23b457820 104 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 93 7.9E-7 T 14-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HL41_08220 bb7ee49ad2d7ba75cae009d23b457820 104 Gene3D G3DSA:3.30.420.130 1 101 7.7E-14 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily HL41_08220 bb7ee49ad2d7ba75cae009d23b457820 104 SUPERFAMILY SSF53146 1 101 2.22E-14 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily HL41_02120 60e65c5f1b728fb0f6bc31116473037f 507 Pfam PF12838 4Fe-4S dicluster domain 21 67 4.5E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_02120 60e65c5f1b728fb0f6bc31116473037f 507 PIRSF PIRSF500061 6 507 1.3E-187 T 14-10-2018 HL41_02120 60e65c5f1b728fb0f6bc31116473037f 507 Pfam PF01645 Conserved region in glutamate synthase 112 475 1.4E-134 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 HL41_02120 60e65c5f1b728fb0f6bc31116473037f 507 SUPERFAMILY SSF51395 93 492 1.17E-123 T 14-10-2018 HL41_02120 60e65c5f1b728fb0f6bc31116473037f 507 PIRSF PIRSF006429 6 507 2.6E-149 T 14-10-2018 IPR024188 Glutamate synthase large subunit-like protein HL41_02120 60e65c5f1b728fb0f6bc31116473037f 507 SUPERFAMILY SSF54862 7 94 9.86E-18 T 14-10-2018 HL41_02120 60e65c5f1b728fb0f6bc31116473037f 507 Gene3D G3DSA:3.20.20.70 127 505 3.1E-130 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_02120 60e65c5f1b728fb0f6bc31116473037f 507 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_02120 60e65c5f1b728fb0f6bc31116473037f 507 Gene3D G3DSA:3.30.70.20 17 99 5.6E-11 T 14-10-2018 HL41_05835 3666ae8d9958b3bd5d0168daf583cfcf 166 SUPERFAMILY SSF53098 1 159 1.26E-27 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily HL41_05835 3666ae8d9958b3bd5d0168daf583cfcf 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 8.8E-11 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HL41_05835 3666ae8d9958b3bd5d0168daf583cfcf 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 8.8E-11 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HL41_05835 3666ae8d9958b3bd5d0168daf583cfcf 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 8.8E-11 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HL41_05835 3666ae8d9958b3bd5d0168daf583cfcf 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 8.8E-11 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HL41_05835 3666ae8d9958b3bd5d0168daf583cfcf 166 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 158 2.3E-25 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HL41_05835 3666ae8d9958b3bd5d0168daf583cfcf 166 Gene3D G3DSA:3.30.420.10 1 163 1.5E-36 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HL41_01475 42d1ff7f7db4cfeb4fd45ff8a18cb796 283 SMART SM00471 107 245 3.8E-4 T 14-10-2018 IPR003607 HD/PDEase domain HL41_01475 42d1ff7f7db4cfeb4fd45ff8a18cb796 283 Gene3D G3DSA:1.10.3210.10 2 254 7.5E-66 T 14-10-2018 HL41_01475 42d1ff7f7db4cfeb4fd45ff8a18cb796 283 SUPERFAMILY SSF109604 3 268 2.08E-63 T 14-10-2018 HL41_01475 42d1ff7f7db4cfeb4fd45ff8a18cb796 283 TIGRFAM TIGR00277 HDIG: HDIG domain 109 213 2.1E-7 T 14-10-2018 IPR006675 HDIG domain HL41_01475 42d1ff7f7db4cfeb4fd45ff8a18cb796 283 Pfam PF08668 HDOD domain 16 215 2.9E-49 T 14-10-2018 IPR013976 Metal-dependent hydrolase HDOD HL41_01765 584d06f3e3871fa43a7d950e3047a8a5 369 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 355 369 2.0E-5 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 HL41_01765 584d06f3e3871fa43a7d950e3047a8a5 369 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 70 90 2.0E-5 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 HL41_01765 584d06f3e3871fa43a7d950e3047a8a5 369 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 59 283 3.0E-18 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HL41_01765 584d06f3e3871fa43a7d950e3047a8a5 369 Gene3D G3DSA:2.40.420.20 294 361 1.9E-93 T 14-10-2018 HL41_01765 584d06f3e3871fa43a7d950e3047a8a5 369 Gene3D G3DSA:1.10.287.470 93 166 1.9E-93 T 14-10-2018 HL41_01765 584d06f3e3871fa43a7d950e3047a8a5 369 Gene3D G3DSA:2.40.50.100 58 200 1.9E-93 T 14-10-2018 HL41_01765 584d06f3e3871fa43a7d950e3047a8a5 369 Gene3D G3DSA:2.40.30.170 47 293 1.9E-93 T 14-10-2018 HL41_01765 584d06f3e3871fa43a7d950e3047a8a5 369 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 43 363 3.8E-85 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 HL41_01765 584d06f3e3871fa43a7d950e3047a8a5 369 SUPERFAMILY SSF111369 50 288 6.54E-63 T 14-10-2018 HL41_00645 cd7934b511c501f3f4889aa392f415d2 440 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 66 232 2.9E-52 T 14-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_00645 cd7934b511c501f3f4889aa392f415d2 440 Gene3D G3DSA:3.30.70.2130 107 254 1.3E-123 T 14-10-2018 HL41_00645 cd7934b511c501f3f4889aa392f415d2 440 TIGRFAM TIGR02535 hyp_Hser_kinase: proposed homoserine kinase 30 429 5.6E-186 T 14-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_00645 cd7934b511c501f3f4889aa392f415d2 440 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 34 428 3.4E-115 T 14-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_00645 cd7934b511c501f3f4889aa392f415d2 440 Pfam PF01676 Metalloenzyme superfamily 31 409 3.7E-36 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 HL41_00645 cd7934b511c501f3f4889aa392f415d2 440 SUPERFAMILY SSF53649 32 393 2.02E-30 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 HL41_00645 cd7934b511c501f3f4889aa392f415d2 440 PIRSF PIRSF006392 28 435 8.0E-128 T 14-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HL41_00645 cd7934b511c501f3f4889aa392f415d2 440 Gene3D G3DSA:3.40.720.10 34 424 1.3E-123 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 HL41_05465 ff7e1d47156511a73af9e8694c44ea2b 157 Gene3D G3DSA:1.10.455.10 2 157 3.6E-65 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily HL41_05465 ff7e1d47156511a73af9e8694c44ea2b 157 SUPERFAMILY SSF47973 1 150 1.96E-61 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily HL41_05465 ff7e1d47156511a73af9e8694c44ea2b 157 Pfam PF00177 Ribosomal protein S7p/S5e 1 150 6.4E-68 T 14-10-2018 IPR023798 Ribosomal protein S7 domain HL41_05465 ff7e1d47156511a73af9e8694c44ea2b 157 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 157 1.2E-69 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HL41_05465 ff7e1d47156511a73af9e8694c44ea2b 157 PIRSF PIRSF002122 4 157 1.4E-62 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 HL41_05465 ff7e1d47156511a73af9e8694c44ea2b 157 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 157 36.767 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HL41_05465 ff7e1d47156511a73af9e8694c44ea2b 157 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 Pfam PF13174 Tetratricopeptide repeat 450 473 0.02 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 Gene3D G3DSA:1.25.40.10 27 314 9.3E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 SUPERFAMILY SSF48452 46 330 4.64E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 SMART SM00028 70 103 470.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 SMART SM00028 172 205 0.036 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 SMART SM00028 409 443 32.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 SMART SM00028 444 477 0.33 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 SMART SM00028 274 304 13.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 SMART SM00028 138 171 0.0053 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 SMART SM00028 39 69 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 SUPERFAMILY SSF48452 358 508 5.96E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 Pfam PF09295 ChAPs (Chs5p-Arf1p-binding proteins) 69 191 1.3E-7 T 14-10-2018 IPR015374 Chs5p-Arf1p binding HL41_03315 28a06d3d844d878aa9e322e2b93e4ed9 528 Gene3D G3DSA:1.25.40.10 315 518 2.0E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 SUPERFAMILY SSF51569 3 288 7.33E-102 T 14-10-2018 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 63.604 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 SMART SM01130 2 290 2.0E-136 T 14-10-2018 IPR002220 DapA-like GO:0016829 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 3.5E-31 T 14-10-2018 IPR002220 DapA-like GO:0016829 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 3.5E-31 T 14-10-2018 IPR002220 DapA-like GO:0016829 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 3.5E-31 T 14-10-2018 IPR002220 DapA-like GO:0016829 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 3.5E-31 T 14-10-2018 IPR002220 DapA-like GO:0016829 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 Gene3D G3DSA:3.20.20.70 1 292 7.1E-111 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 Pfam PF00701 Dihydrodipicolinate synthetase family 3 288 7.0E-96 T 14-10-2018 IPR002220 DapA-like GO:0016829 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 PIRSF PIRSF001365 1 292 6.1E-91 T 14-10-2018 IPR002220 DapA-like GO:0016829 HL41_07980 e3d8fba694929de483f79dbd6968538f 293 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 288 9.6E-107 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_02495 707ff43719303c19f4f92a9963c0f209 247 Pfam PF02361 Cobalt transport protein 10 216 7.8E-30 T 14-10-2018 IPR003339 ABC/ECF transporter, transmembrane component HL41_02495 707ff43719303c19f4f92a9963c0f209 247 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 16 212 1.8E-42 T 14-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 Pfam PF07724 AAA domain (Cdc48 subfamily) 110 307 4.9E-47 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 Gene3D G3DSA:3.40.50.300 51 311 1.6E-108 T 14-10-2018 HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 SUPERFAMILY SSF52540 57 398 2.54E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 Gene3D G3DSA:3.30.50.30 2 47 6.1E-21 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 3 411 52.9 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 SUPERFAMILY SSF57716 8 43 9.98E-12 T 14-10-2018 HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 SMART SM00382 109 266 5.9E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 Pfam PF06689 ClpX C4-type zinc finger 8 45 2.1E-20 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 SMART SM01086 313 407 9.1E-35 T 14-10-2018 IPR019489 Clp ATPase, C-terminal HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 SMART SM00994 7 46 6.9E-24 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 313 391 5.4E-17 T 14-10-2018 IPR019489 Clp ATPase, C-terminal HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 4 408 1.3E-198 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HL41_05280 658b6dd0268c717561d0aadc0ea6960c 417 Gene3D G3DSA:1.10.8.60 312 417 7.5E-40 T 14-10-2018 HL41_08180 b35e45ffb5a19ed52e961aa4e97a74a1 253 Pfam PF13938 Putative heavy-metal chelation 9 91 5.7E-14 T 14-10-2018 IPR025251 Domain of unknown function DUF4213 HL41_08180 b35e45ffb5a19ed52e961aa4e97a74a1 253 Pfam PF04016 Putative heavy-metal chelation 107 236 7.2E-29 T 14-10-2018 IPR007161 Putative heavy-metal chelation domain HL41_08180 b35e45ffb5a19ed52e961aa4e97a74a1 253 SUPERFAMILY SSF159713 3 237 5.1E-42 T 14-10-2018 HL41_08180 b35e45ffb5a19ed52e961aa4e97a74a1 253 Gene3D G3DSA:3.40.50.11590 105 214 8.0E-25 T 14-10-2018 HL41_08180 b35e45ffb5a19ed52e961aa4e97a74a1 253 Gene3D G3DSA:3.30.390.100 16 219 8.0E-25 T 14-10-2018 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 Gene3D G3DSA:1.10.3120.10 117 423 4.1E-58 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 PIRSF PIRSF003095 1 428 4.7E-92 T 14-10-2018 IPR005215 Trigger factor GO:0015031 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 SUPERFAMILY SSF54534 135 252 1.32E-14 T 14-10-2018 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 SUPERFAMILY SSF109998 253 427 1.28E-29 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 TIGRFAM TIGR00115 tig: trigger factor 13 400 5.5E-91 T 14-10-2018 IPR005215 Trigger factor GO:0015031 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 Gene3D G3DSA:3.30.70.1050 1 116 1.6E-29 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 Hamap MF_00303 Trigger factor [tig]. 1 424 18.704 T 14-10-2018 IPR005215 Trigger factor GO:0015031 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 267 400 4.5E-21 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 Gene3D G3DSA:3.10.50.40 153 251 4.1E-58 T 14-10-2018 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 SUPERFAMILY SSF102735 1 130 6.54E-29 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 HL41_05290 43bf9432ac1c0506ab8936e250620b84 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 146 6.4E-33 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HL41_05350 d68ae0a0e191776286e17f0ccba7fced 149 ProSitePatterns PS00475 Ribosomal protein L15 signature. 111 141 - T 14-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05350 d68ae0a0e191776286e17f0ccba7fced 149 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 147 22.441 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 HL41_05350 d68ae0a0e191776286e17f0ccba7fced 149 SUPERFAMILY SSF52080 5 145 2.35E-48 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily HL41_05350 d68ae0a0e191776286e17f0ccba7fced 149 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 145 3.2E-41 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P HL41_05350 d68ae0a0e191776286e17f0ccba7fced 149 Gene3D G3DSA:3.100.10.10 66 149 6.0E-24 T 14-10-2018 HL41_05350 d68ae0a0e191776286e17f0ccba7fced 149 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 3 145 2.8E-56 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_06525 8e88f4291aa1511cd1677d34c061b4f2 315 Gene3D G3DSA:2.40.30.170 43 307 2.0E-58 T 14-10-2018 HL41_06525 8e88f4291aa1511cd1677d34c061b4f2 315 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 308 2.5E-32 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 HL41_06525 8e88f4291aa1511cd1677d34c061b4f2 315 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 48 300 3.9E-25 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HL41_06525 8e88f4291aa1511cd1677d34c061b4f2 315 SUPERFAMILY SSF111369 46 305 6.93E-19 T 14-10-2018 HL41_06525 8e88f4291aa1511cd1677d34c061b4f2 315 Gene3D G3DSA:1.10.287.470 80 185 2.0E-58 T 14-10-2018 HL41_06525 8e88f4291aa1511cd1677d34c061b4f2 315 Gene3D G3DSA:2.40.50.100 46 220 2.0E-58 T 14-10-2018 HL41_05210 94e7d9d659fc559f47fc67bbd7fcdf13 663 SMART SM00955 275 558 4.9E-85 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 HL41_05210 94e7d9d659fc559f47fc67bbd7fcdf13 663 SUPERFAMILY SSF50249 225 600 6.85E-98 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_05210 94e7d9d659fc559f47fc67bbd7fcdf13 663 Pfam PF00773 RNB domain 275 557 8.2E-69 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 761 7.0E-58 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Gene3D G3DSA:1.10.1780.10 1 148 4.6E-37 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 SUPERFAMILY SSF52540 160 548 1.42E-103 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 SMART SM01086 767 857 1.5E-38 T 14-10-2018 IPR019489 Clp ATPase, C-terminal HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 10 837 8.7E-267 T 14-10-2018 IPR017729 Type VI secretion system, ATPase ClpV1 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Gene3D G3DSA:3.40.50.300 553 766 1.8E-91 T 14-10-2018 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 851 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 767 847 2.6E-27 T 14-10-2018 IPR019489 Clp ATPase, C-terminal HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 144 6.4E-11 T 14-10-2018 IPR004176 Clp, N-terminal HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.1E-13 T 14-10-2018 IPR004176 Clp, N-terminal HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 SUPERFAMILY SSF52540 549 853 2.29E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 SMART SM00382 600 832 2.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 SMART SM00382 198 343 1.0E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Gene3D G3DSA:3.40.50.300 344 547 1.1E-72 T 14-10-2018 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Gene3D G3DSA:1.10.8.60 767 862 7.9E-31 T 14-10-2018 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 319 8.9E-14 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 Gene3D G3DSA:3.40.50.300 149 342 1.6E-78 T 14-10-2018 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 7.2E-44 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 7.2E-44 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 7.2E-44 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 7.2E-44 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 HL41_03560 33909f9982538a8aee2c3ca87e589e2a 863 SUPERFAMILY SSF81923 4 156 9.12E-41 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 HL41_06745 1c26f3d905c2c505d7e43d456a6fead7 400 Gene3D G3DSA:3.20.110.20 2 375 1.5E-20 T 14-10-2018 HL41_06745 1c26f3d905c2c505d7e43d456a6fead7 400 Pfam PF03065 Glycosyl hydrolase family 57 7 327 3.1E-45 T 14-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 HL41_06745 1c26f3d905c2c505d7e43d456a6fead7 400 SUPERFAMILY SSF88713 2 345 1.5E-44 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HL41_08100 e98fd46ba3018e411c046451569862f3 336 Gene3D G3DSA:1.25.40.10 10 221 7.0E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_08100 e98fd46ba3018e411c046451569862f3 336 SMART SM00028 38 71 55.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_08100 e98fd46ba3018e411c046451569862f3 336 SMART SM00028 141 174 0.33 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_08100 e98fd46ba3018e411c046451569862f3 336 SMART SM00028 107 140 290.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_08100 e98fd46ba3018e411c046451569862f3 336 Pfam PF03704 Bacterial transcriptional activator domain 40 167 1.6E-5 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain HL41_08100 e98fd46ba3018e411c046451569862f3 336 SUPERFAMILY SSF48452 39 184 1.9E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_03620 a1c09cb8c3de705808d5fdba5fc11fac 126 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 105 22.418 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HL41_03620 a1c09cb8c3de705808d5fdba5fc11fac 126 Pfam PF02410 Ribosomal silencing factor during starvation 9 104 6.7E-23 T 14-10-2018 HL41_03620 a1c09cb8c3de705808d5fdba5fc11fac 126 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 7.0E-32 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HL41_03620 a1c09cb8c3de705808d5fdba5fc11fac 126 Gene3D G3DSA:3.30.460.10 1 119 2.5E-32 T 14-10-2018 HL41_03620 a1c09cb8c3de705808d5fdba5fc11fac 126 SUPERFAMILY SSF81301 1 110 2.78E-34 T 14-10-2018 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 SUPERFAMILY SSF88697 271 352 2.44E-17 T 14-10-2018 IPR015947 PUA-like superfamily HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 TIGRFAM TIGR01027 proB: glutamate 5-kinase 1 351 1.5E-121 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 Gene3D G3DSA:2.30.130.10 260 353 3.5E-24 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 SMART SM00359 271 352 1.3E-14 T 14-10-2018 IPR002478 PUA domain GO:0003723 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 ProSitePatterns PS00902 Glutamate 5-kinase signature. 201 218 - T 14-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 Gene3D G3DSA:3.40.1160.10 1 259 3.3E-82 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 SUPERFAMILY SSF53633 2 251 1.19E-62 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 Pfam PF00696 Amino acid kinase family 2 228 2.2E-40 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 Hamap MF_00456 Glutamate 5-kinase [proB]. 1 253 33.696 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 PIRSF PIRSF000729 1 354 1.9E-124 T 14-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 Pfam PF01472 PUA domain 271 332 1.5E-16 T 14-10-2018 IPR002478 PUA domain GO:0003723 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 PRINTS PR00474 Glutamate 5-kinase family signature 203 223 4.8E-53 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 PRINTS PR00474 Glutamate 5-kinase family signature 110 131 4.8E-53 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 PRINTS PR00474 Glutamate 5-kinase family signature 36 50 4.8E-53 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 PRINTS PR00474 Glutamate 5-kinase family signature 70 98 4.8E-53 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HL41_06475 8345eca26016930fe2e677e84c2b0aa8 355 PRINTS PR00474 Glutamate 5-kinase family signature 142 169 4.8E-53 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HL41_01000 651a32b3cd35cecacfb4c00878640bd2 313 SUPERFAMILY SSF64518 1 312 9.15E-51 T 14-10-2018 HL41_01000 651a32b3cd35cecacfb4c00878640bd2 313 Pfam PF00700 Bacterial flagellin C-terminal helical region 231 312 1.1E-6 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HL41_01000 651a32b3cd35cecacfb4c00878640bd2 313 Gene3D G3DSA:1.20.1330.10 40 260 3.1E-37 T 14-10-2018 HL41_01000 651a32b3cd35cecacfb4c00878640bd2 313 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 140 2.8E-16 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HL41_01000 651a32b3cd35cecacfb4c00878640bd2 313 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 230 9.9E-44 T 14-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 PRINTS PR00955 Flagellar motor switch protein FliM signature 113 132 1.0E-19 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 1.0E-19 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 PRINTS PR00955 Flagellar motor switch protein FliM signature 88 104 1.0E-19 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 PRINTS PR00955 Flagellar motor switch protein FliM signature 210 228 1.0E-19 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 Gene3D G3DSA:3.40.1550.10 45 229 4.9E-51 T 14-10-2018 IPR028976 CheC-like superfamily HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 SUPERFAMILY SSF101801 246 323 2.62E-17 T 14-10-2018 IPR036429 SpoA-like superfamily HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 SUPERFAMILY SSF103039 5 228 2.88E-18 T 14-10-2018 IPR028976 CheC-like superfamily HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 PIRSF PIRSF002888 1 329 2.1E-92 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 317 2.0E-89 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 250 319 2.1E-20 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 Pfam PF02154 Flagellar motor switch protein FliM 37 228 3.4E-52 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HL41_02640 46ee5456d402311f6abee1d8310dcb09 329 Gene3D G3DSA:2.30.330.10 240 327 5.9E-11 T 14-10-2018 IPR036429 SpoA-like superfamily HL41_08520 35fef291f995e54a93fbc786a1407e54 488 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 424 2.3E-173 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 HL41_08520 35fef291f995e54a93fbc786a1407e54 488 SUPERFAMILY SSF50475 4 318 8.24E-125 T 14-10-2018 HL41_08520 35fef291f995e54a93fbc786a1407e54 488 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 9 441 1.1E-206 T 14-10-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 HL41_08520 35fef291f995e54a93fbc786a1407e54 488 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 7 449 8.4E-162 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 HL41_08520 35fef291f995e54a93fbc786a1407e54 488 SUPERFAMILY SSF143968 319 480 1.7E-59 T 14-10-2018 HL41_08520 35fef291f995e54a93fbc786a1407e54 488 Gene3D G3DSA:3.40.1670.10 333 448 2.5E-39 T 14-10-2018 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 Gene3D G3DSA:3.40.50.620 1 313 2.4E-135 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 458 1.4E-165 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 SUPERFAMILY SSF52374 4 297 1.45E-112 T 14-10-2018 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 302 4.7E-103 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 Gene3D G3DSA:1.10.10.350 367 466 1.5E-24 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 SUPERFAMILY SSF48163 298 460 4.58E-35 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 3 460 32.602 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 1.1E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 1.1E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 202 1.1E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 1.1E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HL41_03130 eb4634f3d82368a5ac089c107f0c36d6 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 178 188 1.1E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 13 409 4.4E-92 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 Gene3D G3DSA:3.30.300.30 123 225 3.8E-11 T 14-10-2018 HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 PRINTS PR01009 Flagellar M-ring protein signature 341 365 3.5E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 PRINTS PR01009 Flagellar M-ring protein signature 266 284 3.5E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 PRINTS PR01009 Flagellar M-ring protein signature 154 168 3.5E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 PRINTS PR01009 Flagellar M-ring protein signature 197 215 3.5E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 PRINTS PR01009 Flagellar M-ring protein signature 122 140 3.5E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 Pfam PF08345 Flagellar M-ring protein C-terminal 253 408 7.6E-36 T 14-10-2018 IPR013556 Flagellar M-ring C-terminal HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 PIRSF PIRSF004862 2 510 5.9E-131 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HL41_00545 15228fe1eb6a60bb8583a04fee2e60c6 523 Pfam PF01514 Secretory protein of YscJ/FliF family 35 216 8.6E-64 T 14-10-2018 IPR006182 Secretory protein YscJ/FliF HL41_03835 d997001cc91a96fad33690999946dfc5 1237 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 706 712 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HL41_03835 d997001cc91a96fad33690999946dfc5 1237 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 703 715 1.0E-12 T 14-10-2018 HL41_03835 d997001cc91a96fad33690999946dfc5 1237 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 390 406 1.0E-12 T 14-10-2018 HL41_03835 d997001cc91a96fad33690999946dfc5 1237 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 763 787 1.0E-12 T 14-10-2018 HL41_03835 d997001cc91a96fad33690999946dfc5 1237 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 453 467 1.0E-12 T 14-10-2018 HL41_03835 d997001cc91a96fad33690999946dfc5 1237 Pfam PF07669 Eco57I restriction-modification methylase 703 837 1.2E-8 T 14-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 HL41_03835 d997001cc91a96fad33690999946dfc5 1237 SUPERFAMILY SSF53335 220 856 2.78E-56 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_01405 b3f58a5dd0fd521575516f89d27ea793 202 Pfam PF02132 RecR protein 42 78 1.9E-9 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger HL41_01405 b3f58a5dd0fd521575516f89d27ea793 202 SUPERFAMILY SSF111304 6 199 1.11E-63 T 14-10-2018 IPR023627 Recombination protein RecR HL41_01405 b3f58a5dd0fd521575516f89d27ea793 202 TIGRFAM TIGR00615 recR: recombination protein RecR 6 196 1.4E-61 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HL41_01405 b3f58a5dd0fd521575516f89d27ea793 202 Gene3D G3DSA:1.10.8.420 8 54 8.0E-13 T 14-10-2018 HL41_01405 b3f58a5dd0fd521575516f89d27ea793 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 73.417 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HL41_01405 b3f58a5dd0fd521575516f89d27ea793 202 Gene3D G3DSA:3.40.1360.10 78 198 6.2E-38 T 14-10-2018 HL41_01405 b3f58a5dd0fd521575516f89d27ea793 202 SMART SM00493 81 166 4.7E-4 T 14-10-2018 IPR006171 TOPRIM domain HL41_01405 b3f58a5dd0fd521575516f89d27ea793 202 Pfam PF13662 Toprim domain 82 172 7.5E-18 T 14-10-2018 IPR006171 TOPRIM domain HL41_04980 f0f73693277f67755d02749fcbcfed68 146 Pfam PF07977 FabA-like domain 12 137 2.2E-33 T 14-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HL41_04980 f0f73693277f67755d02749fcbcfed68 146 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 4 140 1.2E-52 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HL41_04980 f0f73693277f67755d02749fcbcfed68 146 Gene3D G3DSA:3.10.129.10 1 144 6.3E-54 T 14-10-2018 HL41_04980 f0f73693277f67755d02749fcbcfed68 146 SUPERFAMILY SSF54637 3 140 1.66E-44 T 14-10-2018 IPR029069 HotDog domain superfamily HL41_04980 f0f73693277f67755d02749fcbcfed68 146 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 3 144 32.707 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HL41_01275 b3e99162d7b38cc8d2b2af2d007f9bd9 301 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 86 102 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site HL41_01275 b3e99162d7b38cc8d2b2af2d007f9bd9 301 Gene3D G3DSA:1.10.600.10 3 300 7.7E-98 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily HL41_01275 b3e99162d7b38cc8d2b2af2d007f9bd9 301 Pfam PF00348 Polyprenyl synthetase 39 271 3.9E-55 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 HL41_01275 b3e99162d7b38cc8d2b2af2d007f9bd9 301 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 220 232 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site HL41_01275 b3e99162d7b38cc8d2b2af2d007f9bd9 301 SUPERFAMILY SSF48576 9 292 2.67E-81 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 Gene3D G3DSA:3.40.50.80 97 213 2.4E-23 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 Gene3D G3DSA:2.10.240.10 215 254 8.9E-6 T 14-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 Pfam PF00970 Oxidoreductase FAD-binding domain 6 94 2.5E-5 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 PIRSF PIRSF006816 1 257 6.1E-53 T 14-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 186 194 8.1E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 103 122 8.1E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 31 43 8.1E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 Gene3D G3DSA:2.40.30.10 2 94 1.5E-23 T 14-10-2018 HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 SUPERFAMILY SSF52343 91 252 4.98E-30 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 215 253 3.9E-10 T 14-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 Pfam PF00175 Oxidoreductase NAD-binding domain 106 200 7.0E-7 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 HL41_09155 b185af7bbde219d365cfd60a0f0f44dc 258 SUPERFAMILY SSF63380 2 96 3.4E-18 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel HL41_03605 f027b94629ed28ff8af637db21478424 102 Pfam PF14279 HNH endonuclease 37 81 2.0E-14 T 14-10-2018 IPR029471 HNH endonuclease 5 HL41_03605 f027b94629ed28ff8af637db21478424 102 SMART SM00507 26 77 9.1E-10 T 14-10-2018 IPR003615 HNH nuclease HL41_03605 f027b94629ed28ff8af637db21478424 102 Gene3D G3DSA:3.30.40.60 3 102 8.5E-36 T 14-10-2018 HL41_06805 39fb69b43d462a0273efa939a25e46e4 375 SUPERFAMILY SSF53383 5 368 1.97E-96 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_06805 39fb69b43d462a0273efa939a25e46e4 375 Pfam PF00266 Aminotransferase class-V 7 363 1.1E-80 T 14-10-2018 IPR000192 Aminotransferase class V domain HL41_06805 39fb69b43d462a0273efa939a25e46e4 375 Gene3D G3DSA:3.40.640.10 18 257 1.4E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_06805 39fb69b43d462a0273efa939a25e46e4 375 PIRSF PIRSF005572 4 375 3.0E-123 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 HL41_06805 39fb69b43d462a0273efa939a25e46e4 375 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HL41_06805 39fb69b43d462a0273efa939a25e46e4 375 Gene3D G3DSA:3.90.1150.10 7 367 1.4E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_08245 15054ddcd718711ed3ce8bf8aa5976ce 853 Gene3D G3DSA:3.30.1490.20 117 304 4.4E-51 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HL41_08245 15054ddcd718711ed3ce8bf8aa5976ce 853 Gene3D G3DSA:3.30.470.20 305 454 2.3E-36 T 14-10-2018 HL41_08245 15054ddcd718711ed3ce8bf8aa5976ce 853 SUPERFAMILY SSF52009 455 560 2.62E-24 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 HL41_08245 15054ddcd718711ed3ce8bf8aa5976ce 853 Pfam PF00391 PEP-utilising enzyme, mobile domain 481 553 3.7E-17 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HL41_08245 15054ddcd718711ed3ce8bf8aa5976ce 853 Gene3D G3DSA:3.50.30.10 456 585 2.5E-28 T 14-10-2018 HL41_08245 15054ddcd718711ed3ce8bf8aa5976ce 853 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 135 442 1.0E-84 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HL41_08245 15054ddcd718711ed3ce8bf8aa5976ce 853 SUPERFAMILY SSF56059 118 482 4.94E-73 T 14-10-2018 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Gene3D G3DSA:3.30.210.10 260 324 8.2E-28 T 14-10-2018 IPR037160 DNA polymerase, thumb domain superfamily HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 58 75 2.2E-7 T 14-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 295 312 2.2E-7 T 14-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 253 260 2.2E-7 T 14-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Gene3D G3DSA:1.10.150.20 86 153 7.6E-23 T 14-10-2018 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Pfam PF14520 Helix-hairpin-helix domain 93 145 1.8E-10 T 14-10-2018 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 SMART SM00278 126 145 6.5 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 SMART SM00278 51 70 20.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 SMART SM00278 91 110 110.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 SMART SM00481 337 416 8.0E-16 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Pfam PF14791 DNA polymerase beta thumb 253 313 1.8E-20 T 14-10-2018 IPR029398 DNA polymerase beta, thumb domain HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 SMART SM00483 1 313 2.5E-44 T 14-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Gene3D G3DSA:3.30.460.10 155 259 1.5E-33 T 14-10-2018 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Gene3D G3DSA:1.10.150.110 1 85 8.8E-29 T 14-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 PIRSF PIRSF005047 1 571 1.3E-230 T 14-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 SUPERFAMILY SSF89550 336 561 6.8E-48 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Pfam PF14792 DNA polymerase beta palm 157 224 1.5E-6 T 14-10-2018 IPR028207 DNA polymerase beta, palm domain HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 SUPERFAMILY SSF81301 155 313 3.11E-47 T 14-10-2018 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Gene3D G3DSA:3.20.20.140 325 571 2.7E-71 T 14-10-2018 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Pfam PF14716 Helix-hairpin-helix domain 3 72 2.6E-23 T 14-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 Pfam PF02811 PHP domain 338 474 2.2E-8 T 14-10-2018 IPR004013 PHP domain GO:0003824 HL41_01980 e86e05c8b7ca318c54f71c014bcfd331 572 SUPERFAMILY SSF47802 1 84 6.93E-21 T 14-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily HL41_00725 60110f6d86e755b06eef5164e51c82e8 280 Gene3D G3DSA:3.30.70.890 163 280 2.0E-20 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily HL41_00725 60110f6d86e755b06eef5164e51c82e8 280 PIRSF PIRSF010376 2 279 3.8E-69 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 HL41_00725 60110f6d86e755b06eef5164e51c82e8 280 SUPERFAMILY SSF54211 4 158 2.05E-32 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_00725 60110f6d86e755b06eef5164e51c82e8 280 Pfam PF08544 GHMP kinases C terminal 215 256 2.1E-5 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain HL41_00725 60110f6d86e755b06eef5164e51c82e8 280 SUPERFAMILY SSF55060 165 275 1.44E-18 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily HL41_00725 60110f6d86e755b06eef5164e51c82e8 280 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 270 1.0E-54 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 HL41_00725 60110f6d86e755b06eef5164e51c82e8 280 Pfam PF00288 GHMP kinases N terminal domain 87 141 3.1E-8 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 HL41_00725 60110f6d86e755b06eef5164e51c82e8 280 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 4 276 27.592 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 HL41_00725 60110f6d86e755b06eef5164e51c82e8 280 Gene3D G3DSA:3.30.230.10 2 160 7.7E-48 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_05365 86e58e42d9cb5ba466da7910f489340c 129 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 11 129 1.3E-43 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05365 86e58e42d9cb5ba466da7910f489340c 129 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 9 129 29.919 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05365 86e58e42d9cb5ba466da7910f489340c 129 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 9 129 2.6E-49 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05365 86e58e42d9cb5ba466da7910f489340c 129 SUPERFAMILY SSF53137 10 127 1.37E-54 T 14-10-2018 HL41_05365 86e58e42d9cb5ba466da7910f489340c 129 Gene3D G3DSA:3.30.420.100 8 129 8.0E-47 T 14-10-2018 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 SUPERFAMILY SSF51735 3 143 4.21E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 Gene3D G3DSA:3.90.110.10 145 308 2.2E-59 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 SUPERFAMILY SSF56327 143 304 4.76E-51 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 Gene3D G3DSA:3.40.50.720 1 144 2.7E-51 T 14-10-2018 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 PRINTS PR00086 L-lactate dehydrogenase signature 140 158 2.8E-33 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 2.8E-33 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 PRINTS PR00086 L-lactate dehydrogenase signature 116 136 2.8E-33 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 PRINTS PR00086 L-lactate dehydrogenase signature 170 183 2.8E-33 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 2.8E-33 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 3 142 6.0E-41 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 PIRSF PIRSF000102 1 308 1.3E-106 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 3 304 1.8E-123 T 14-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 Hamap MF_00487 Malate dehydrogenase [mdh]. 2 307 42.518 T 14-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 HL41_05185 5e2165536b1748c988f21c0d5f17e881 309 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 300 3.1E-29 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 HL41_00635 a90081939c5f4c91cc42cf9193ad6c76 236 Pfam PF00902 Sec-independent protein translocase protein (TatC) 14 219 8.9E-30 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_00635 a90081939c5f4c91cc42cf9193ad6c76 236 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 4.4E-6 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_00635 a90081939c5f4c91cc42cf9193ad6c76 236 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 86 104 4.4E-6 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_00635 a90081939c5f4c91cc42cf9193ad6c76 236 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 104 130 4.4E-6 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_06050 ea7de559c785e466aea120c07db16b46 227 Pfam PF00578 AhpC/TSA family 13 143 8.8E-35 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HL41_06050 ea7de559c785e466aea120c07db16b46 227 PIRSF PIRSF000239 6 226 4.3E-80 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HL41_06050 ea7de559c785e466aea120c07db16b46 227 Gene3D G3DSA:3.40.30.10 11 152 2.3E-51 T 14-10-2018 HL41_06050 ea7de559c785e466aea120c07db16b46 227 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 164 213 6.1E-18 T 14-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HL41_06050 ea7de559c785e466aea120c07db16b46 227 SUPERFAMILY SSF52833 10 226 3.71E-73 T 14-10-2018 IPR036249 Thioredoxin-like superfamily HL41_06050 ea7de559c785e466aea120c07db16b46 227 Gene3D G3DSA:3.30.1020.20 153 227 3.7E-23 T 14-10-2018 HL41_06050 ea7de559c785e466aea120c07db16b46 227 Hamap MF_00401 Peroxiredoxin. 11 226 47.159 T 14-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 Pfam PF13426 PAS domain 364 456 3.3E-15 T 14-10-2018 IPR000014 PAS domain HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 Gene3D G3DSA:3.30.450.20 335 468 2.6E-22 T 14-10-2018 HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 SMART SM00267 458 629 4.6E-61 T 14-10-2018 IPR000160 GGDEF domain HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 Gene3D G3DSA:3.30.70.270 469 629 2.3E-53 T 14-10-2018 HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 SUPERFAMILY SSF55785 365 456 4.01E-15 T 14-10-2018 IPR035965 PAS domain superfamily HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 468 628 3.9E-55 T 14-10-2018 IPR000160 GGDEF domain HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 Pfam PF00990 Diguanylate cyclase, GGDEF domain 470 624 7.4E-48 T 14-10-2018 IPR000160 GGDEF domain HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 Pfam PF14827 Double sensory domain of two-component sensor kinase 91 302 3.2E-7 T 14-10-2018 IPR029150 Double Cache domain 3 HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 SUPERFAMILY SSF55073 474 628 4.0E-46 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_00390 7e2d29dc9d25faff61e31e93a7ddcaa8 630 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 347 465 3.3E-13 T 14-10-2018 IPR000014 PAS domain HL41_05140 75d358b6b817d90775ed3c208279b412 376 PIRSF PIRSF005622 8 376 7.5E-148 T 14-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 HL41_05140 75d358b6b817d90775ed3c208279b412 376 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 10 374 8.6E-137 T 14-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 HL41_05140 75d358b6b817d90775ed3c208279b412 376 Pfam PF01924 Hydrogenase formation hypA family 20 372 5.3E-143 T 14-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 HL41_05140 75d358b6b817d90775ed3c208279b412 376 Gene3D G3DSA:3.40.50.11740 69 308 1.9E-101 T 14-10-2018 HL41_05140 75d358b6b817d90775ed3c208279b412 376 Gene3D G3DSA:1.10.10.2140 323 374 1.4E-25 T 14-10-2018 HL41_05140 75d358b6b817d90775ed3c208279b412 376 Gene3D G3DSA:3.40.50.11750 25 268 1.9E-101 T 14-10-2018 HL41_07380 140fc6094cb2dbd8ecc2a8aee22666b6 158 Pfam PF12838 4Fe-4S dicluster domain 72 120 4.3E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_07380 140fc6094cb2dbd8ecc2a8aee22666b6 158 Gene3D G3DSA:3.30.70.20 66 135 1.9E-5 T 14-10-2018 HL41_07380 140fc6094cb2dbd8ecc2a8aee22666b6 158 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 73 84 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07380 140fc6094cb2dbd8ecc2a8aee22666b6 158 SUPERFAMILY SSF54862 36 119 1.23E-16 T 14-10-2018 HL41_07380 140fc6094cb2dbd8ecc2a8aee22666b6 158 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 44 55 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07380 140fc6094cb2dbd8ecc2a8aee22666b6 158 Gene3D G3DSA:3.30.70.20 24 64 1.3E-5 T 14-10-2018 HL41_07380 140fc6094cb2dbd8ecc2a8aee22666b6 158 Pfam PF00037 4Fe-4S binding domain 42 60 7.8E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_04670 64d7ceab688d6b484095f62694021074 446 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 5 440 3.3E-162 T 14-10-2018 HL41_04670 64d7ceab688d6b484095f62694021074 446 Gene3D G3DSA:3.80.30.20 147 382 1.8E-97 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HL41_04670 64d7ceab688d6b484095f62694021074 446 Pfam PF00919 Uncharacterized protein family UPF0004 4 102 4.4E-29 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 HL41_04670 64d7ceab688d6b484095f62694021074 446 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 443 71.337 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 HL41_04670 64d7ceab688d6b484095f62694021074 446 SUPERFAMILY SSF102114 144 374 6.02E-64 T 14-10-2018 HL41_04670 64d7ceab688d6b484095f62694021074 446 Pfam PF01938 TRAM domain 379 441 3.9E-13 T 14-10-2018 IPR002792 TRAM domain HL41_04670 64d7ceab688d6b484095f62694021074 446 Pfam PF04055 Radical SAM superfamily 154 325 7.2E-40 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_04670 64d7ceab688d6b484095f62694021074 446 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 439 4.7E-157 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 HL41_04670 64d7ceab688d6b484095f62694021074 446 SMART SM00729 150 368 5.2E-61 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_04670 64d7ceab688d6b484095f62694021074 446 Gene3D G3DSA:3.40.50.12160 3 133 5.4E-35 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily HL41_04670 64d7ceab688d6b484095f62694021074 446 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 154 174 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 Gene3D G3DSA:2.40.30.10 176 265 3.2E-28 T 14-10-2018 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 163 6.8E-18 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 SUPERFAMILY SSF46785 441 508 4.08E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 SUPERFAMILY SSF50465 266 363 4.93E-18 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 Gene3D G3DSA:3.40.50.300 2 170 7.3E-53 T 14-10-2018 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 SUPERFAMILY SSF52540 3 195 7.65E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 29 44 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 4 635 3.5E-118 T 14-10-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 Gene3D G3DSA:1.10.10.2770 443 573 1.1E-25 T 14-10-2018 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 Gene3D G3DSA:2.40.30.10 281 368 4.3E-5 T 14-10-2018 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 SUPERFAMILY SSF46785 584 636 1.31E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 Gene3D G3DSA:1.10.10.10 574 635 1.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 SUPERFAMILY SSF50447 177 263 1.02E-23 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 Pfam PF09106 Elongation factor SelB, winged helix 451 500 1.3E-7 T 14-10-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 PRINTS PR00315 GTP-binding elongation factor signature 73 84 5.2E-8 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 PRINTS PR00315 GTP-binding elongation factor signature 57 67 5.2E-8 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 PRINTS PR00315 GTP-binding elongation factor signature 5 18 5.2E-8 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 PRINTS PR00315 GTP-binding elongation factor signature 110 119 5.2E-8 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 Pfam PF09107 Elongation factor SelB, winged helix 587 634 1.3E-15 T 14-10-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 HL41_00855 85bbb0dd0b9792f1ba98fbb1334ee403 637 Pfam PF00009 Elongation factor Tu GTP binding domain 4 167 1.1E-35 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 SUPERFAMILY SSF54211 594 769 8.72E-59 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 Gene3D G3DSA:1.10.8.60 489 583 5.4E-33 T 14-10-2018 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 TIGRFAM TIGR00763 lon: endopeptidase La 9 770 1.8E-298 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 Gene3D G3DSA:3.40.50.300 311 488 6.7E-65 T 14-10-2018 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 675 683 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 PIRSF PIRSF001174 1 774 0.0 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 349 486 2.5E-20 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 Hamap MF_01973 Lon protease [lon]. 8 771 71.969 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 Gene3D G3DSA:3.30.230.10 584 771 2.0E-79 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 Gene3D G3DSA:2.30.130.40 3 112 3.1E-33 T 14-10-2018 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 197 1.0E-39 T 14-10-2018 IPR003111 Lon, substrate-binding domain HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 SUPERFAMILY SSF88697 7 198 1.04E-44 T 14-10-2018 IPR015947 PUA-like superfamily HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 721 6.2E-55 T 14-10-2018 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 725 743 6.2E-55 T 14-10-2018 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 594 610 6.2E-55 T 14-10-2018 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 672 691 6.2E-55 T 14-10-2018 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 353 372 6.2E-55 T 14-10-2018 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 569 770 1.3E-92 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 SUPERFAMILY SSF52540 305 565 9.65E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 Gene3D G3DSA:1.20.58.1480 118 242 2.1E-33 T 14-10-2018 HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 SMART SM00382 345 490 1.5E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_05275 db2c5d4754b0eaf08602896afffd2a0c 806 SMART SM00464 7 199 2.1E-61 T 14-10-2018 IPR003111 Lon, substrate-binding domain HL41_02825 5be5ae464f4995e935981c4008a9a049 287 SUPERFAMILY SSF58104 47 279 5.62E-44 T 14-10-2018 HL41_02825 5be5ae464f4995e935981c4008a9a049 287 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 168 197 2.2E-11 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02825 5be5ae464f4995e935981c4008a9a049 287 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 139 166 2.2E-11 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02825 5be5ae464f4995e935981c4008a9a049 287 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 115 266 4.4E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02825 5be5ae464f4995e935981c4008a9a049 287 SMART SM00283 48 285 2.9E-5 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02825 5be5ae464f4995e935981c4008a9a049 287 Gene3D G3DSA:1.10.287.950 26 287 2.9E-41 T 14-10-2018 HL41_05020 42fd50c99a5796b90012a50d39e86012 381 SMART SM00271 4 62 1.1E-37 T 14-10-2018 IPR001623 DnaJ domain HL41_05020 42fd50c99a5796b90012a50d39e86012 381 SUPERFAMILY SSF46565 1 101 1.15E-36 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_05020 42fd50c99a5796b90012a50d39e86012 381 Pfam PF00226 DnaJ domain 5 67 1.8E-32 T 14-10-2018 IPR001623 DnaJ domain HL41_05020 42fd50c99a5796b90012a50d39e86012 381 PRINTS PR00625 DnaJ domain signature 7 25 1.2E-31 T 14-10-2018 IPR001623 DnaJ domain HL41_05020 42fd50c99a5796b90012a50d39e86012 381 PRINTS PR00625 DnaJ domain signature 25 40 1.2E-31 T 14-10-2018 IPR001623 DnaJ domain HL41_05020 42fd50c99a5796b90012a50d39e86012 381 PRINTS PR00625 DnaJ domain signature 42 62 1.2E-31 T 14-10-2018 IPR001623 DnaJ domain HL41_05020 42fd50c99a5796b90012a50d39e86012 381 PRINTS PR00625 DnaJ domain signature 62 81 1.2E-31 T 14-10-2018 IPR001623 DnaJ domain HL41_05020 42fd50c99a5796b90012a50d39e86012 381 Pfam PF00684 DnaJ central domain 145 205 1.5E-9 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HL41_05020 42fd50c99a5796b90012a50d39e86012 381 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 376 35.825 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HL41_05020 42fd50c99a5796b90012a50d39e86012 381 Gene3D G3DSA:2.60.260.20 253 360 1.5E-26 T 14-10-2018 HL41_05020 42fd50c99a5796b90012a50d39e86012 381 SUPERFAMILY SSF57938 134 209 5.23E-18 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily HL41_05020 42fd50c99a5796b90012a50d39e86012 381 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 348 4.0E-121 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HL41_05020 42fd50c99a5796b90012a50d39e86012 381 Gene3D G3DSA:1.10.287.110 2 109 1.1E-38 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_05020 42fd50c99a5796b90012a50d39e86012 381 Gene3D G3DSA:2.10.230.10 145 209 8.3E-16 T 14-10-2018 HL41_05020 42fd50c99a5796b90012a50d39e86012 381 SUPERFAMILY SSF49493 111 265 3.27E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HL41_05020 42fd50c99a5796b90012a50d39e86012 381 Pfam PF01556 DnaJ C terminal domain 119 331 6.6E-36 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal HL41_05020 42fd50c99a5796b90012a50d39e86012 381 SUPERFAMILY SSF49493 257 342 8.76E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HL41_05020 42fd50c99a5796b90012a50d39e86012 381 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 14-10-2018 IPR018253 DnaJ domain, conserved site HL41_01890 4b78c05a6ada9d2178bf96d9b0c626b2 144 Gene3D G3DSA:3.30.70.20 82 133 1.2E-13 T 14-10-2018 HL41_01890 4b78c05a6ada9d2178bf96d9b0c626b2 144 Pfam PF09383 NIL domain 9 73 1.1E-11 T 14-10-2018 IPR018449 NIL domain HL41_01890 4b78c05a6ada9d2178bf96d9b0c626b2 144 Pfam PF13237 4Fe-4S dicluster domain 79 127 4.4E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_01890 4b78c05a6ada9d2178bf96d9b0c626b2 144 SUPERFAMILY SSF54862 65 134 5.32E-20 T 14-10-2018 HL41_01890 4b78c05a6ada9d2178bf96d9b0c626b2 144 SUPERFAMILY SSF55021 7 76 1.14E-14 T 14-10-2018 HL41_01890 4b78c05a6ada9d2178bf96d9b0c626b2 144 Gene3D G3DSA:3.30.70.260 3 81 8.6E-10 T 14-10-2018 HL41_01890 4b78c05a6ada9d2178bf96d9b0c626b2 144 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_01890 4b78c05a6ada9d2178bf96d9b0c626b2 144 SMART SM00930 3 75 9.7E-14 T 14-10-2018 IPR018449 NIL domain HL41_01790 3eeb71a1a4ae81b2f0e6e127cdfc7176 546 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 542 6.7E-148 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HL41_01790 3eeb71a1a4ae81b2f0e6e127cdfc7176 546 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 25 38 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HL41_01790 3eeb71a1a4ae81b2f0e6e127cdfc7176 546 SUPERFAMILY SSF52540 1 530 2.26E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01790 3eeb71a1a4ae81b2f0e6e127cdfc7176 546 Gene3D G3DSA:3.40.50.300 1 271 2.4E-41 T 14-10-2018 HL41_01790 3eeb71a1a4ae81b2f0e6e127cdfc7176 546 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 502 2.8E-16 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal HL41_01790 3eeb71a1a4ae81b2f0e6e127cdfc7176 546 PIRSF PIRSF003128 1 545 3.9E-156 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HL41_01790 3eeb71a1a4ae81b2f0e6e127cdfc7176 546 Gene3D G3DSA:3.40.50.300 285 544 1.8E-45 T 14-10-2018 HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 Hamap MF_01974 Methionine aminopeptidase [map]. 10 257 38.584 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 174 192 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 Gene3D G3DSA:3.90.230.10 3 256 4.0E-97 T 14-10-2018 HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 Pfam PF00557 Metallopeptidase family M24 20 248 2.4E-46 T 14-10-2018 IPR000994 Peptidase M24 HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 SUPERFAMILY SSF55920 12 256 3.66E-79 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 199 211 2.7E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 98 114 2.7E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 75 88 2.7E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 168 180 2.7E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_05335 4240281d25b47a0ee88e6e5c5969c310 257 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 12 256 7.3E-93 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HL41_04555 2bb18be9ff7ba8eb6520452dc8c53411 164 SUPERFAMILY SSF54197 3 143 1.7E-40 T 14-10-2018 IPR036265 HIT-like superfamily HL41_04555 2bb18be9ff7ba8eb6520452dc8c53411 164 Pfam PF01230 HIT domain 37 127 4.7E-15 T 14-10-2018 IPR001310 Histidine triad (HIT) protein HL41_04555 2bb18be9ff7ba8eb6520452dc8c53411 164 Gene3D G3DSA:3.30.428.10 1 162 3.9E-49 T 14-10-2018 IPR036265 HIT-like superfamily HL41_00290 d42d115b4cf606b7ba0641ffb87b09a6 391 Gene3D G3DSA:3.90.230.10 131 386 1.5E-46 T 14-10-2018 HL41_00290 d42d115b4cf606b7ba0641ffb87b09a6 391 Gene3D G3DSA:3.40.350.10 8 130 5.1E-19 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HL41_00290 d42d115b4cf606b7ba0641ffb87b09a6 391 SUPERFAMILY SSF53092 3 130 1.1E-16 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HL41_00290 d42d115b4cf606b7ba0641ffb87b09a6 391 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 132 2.9E-14 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 HL41_00290 d42d115b4cf606b7ba0641ffb87b09a6 391 SUPERFAMILY SSF55920 92 377 1.01E-44 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like HL41_00290 d42d115b4cf606b7ba0641ffb87b09a6 391 Pfam PF00557 Metallopeptidase family M24 139 371 6.0E-34 T 14-10-2018 IPR000994 Peptidase M24 HL41_08360 2bb188e92d23950933f0cc06be2059cf 367 PIRSF PIRSF004640 1 361 7.7E-139 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HL41_08360 2bb188e92d23950933f0cc06be2059cf 367 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 356 31.547 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HL41_08360 2bb188e92d23950933f0cc06be2059cf 367 Gene3D G3DSA:3.20.20.20 1 260 2.6E-98 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_08360 2bb188e92d23950933f0cc06be2059cf 367 SUPERFAMILY SSF51717 14 207 5.49E-10 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_08360 2bb188e92d23950933f0cc06be2059cf 367 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 351 8.2E-122 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HL41_08360 2bb188e92d23950933f0cc06be2059cf 367 Gene3D G3DSA:3.30.413.10 262 359 1.8E-34 T 14-10-2018 HL41_08360 2bb188e92d23950933f0cc06be2059cf 367 SUPERFAMILY SSF56014 265 357 2.62E-11 T 14-10-2018 HL41_08360 2bb188e92d23950933f0cc06be2059cf 367 Pfam PF04551 GcpE protein 10 352 7.8E-127 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 Pfam PF02910 Fumarate reductase flavoprotein C-term 440 529 1.7E-10 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 SUPERFAMILY SSF46977 428 520 1.7E-20 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 SUPERFAMILY SSF51905 2 410 2.91E-65 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 Gene3D G3DSA:3.90.700.10 242 353 1.4E-156 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 Gene3D G3DSA:1.20.58.100 423 532 2.3E-27 T 14-10-2018 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 PIRSF PIRSF000171 1 532 6.0E-39 T 14-10-2018 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.5E-6 T 14-10-2018 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 350 372 3.5E-6 T 14-10-2018 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 SUPERFAMILY SSF56425 232 347 1.11E-44 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 Gene3D G3DSA:3.50.50.60 7 397 1.4E-156 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 5 517 1.0E-175 T 14-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 HL41_00650 59e5cd6e226fcf6d96bcbdb6d7fc20a2 532 Pfam PF00890 FAD binding domain 7 387 2.2E-99 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 HL41_03420 7634270bb1e249a5042605b4c108f59b 175 Gene3D G3DSA:3.10.20.80 5 79 5.0E-33 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HL41_03420 7634270bb1e249a5042605b4c108f59b 175 Gene3D G3DSA:3.30.110.10 80 175 3.8E-33 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 HL41_03420 7634270bb1e249a5042605b4c108f59b 175 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 11 80 7.8E-31 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HL41_03420 7634270bb1e249a5042605b4c108f59b 175 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 5 174 29.011 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HL41_03420 7634270bb1e249a5042605b4c108f59b 175 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 87 171 5.1E-34 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 HL41_03420 7634270bb1e249a5042605b4c108f59b 175 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 11 173 6.8E-64 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HL41_03420 7634270bb1e249a5042605b4c108f59b 175 SUPERFAMILY SSF55200 87 174 3.14E-30 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 HL41_03420 7634270bb1e249a5042605b4c108f59b 175 SUPERFAMILY SSF54364 9 82 3.27E-29 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HL41_08210 24195ae511bfa103098600dc2f09ed1d 462 SUPERFAMILY SSF56935 27 462 1.1E-7 T 14-10-2018 HL41_08210 24195ae511bfa103098600dc2f09ed1d 462 Pfam PF13372 Alginate export 226 446 1.0E-15 T 14-10-2018 IPR025388 Alginate export domain HL41_01215 71fc46d671451e23095dc29ceb34eaa0 264 SMART SM00893 23 214 3.5E-43 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HL41_01215 71fc46d671451e23095dc29ceb34eaa0 264 Gene3D G3DSA:3.40.50.620 3 263 8.9E-79 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_01215 71fc46d671451e23095dc29ceb34eaa0 264 SUPERFAMILY SSF52402 3 257 3.84E-62 T 14-10-2018 HL41_01215 71fc46d671451e23095dc29ceb34eaa0 264 PIRSF PIRSF000090 2 263 3.5E-69 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 HL41_01215 71fc46d671451e23095dc29ceb34eaa0 264 Pfam PF01012 Electron transfer flavoprotein domain 25 192 6.9E-38 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 HL41_01400 34eca3d704ca2ee9c75bc0ee8e7b6d31 112 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 6 104 1.1E-25 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HL41_01400 34eca3d704ca2ee9c75bc0ee8e7b6d31 112 SUPERFAMILY SSF82607 11 104 5.49E-30 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily HL41_01400 34eca3d704ca2ee9c75bc0ee8e7b6d31 112 Pfam PF02575 YbaB/EbfC DNA-binding family 11 100 1.0E-32 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HL41_01400 34eca3d704ca2ee9c75bc0ee8e7b6d31 112 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 99 21.64 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HL41_01400 34eca3d704ca2ee9c75bc0ee8e7b6d31 112 Gene3D G3DSA:3.30.1310.10 3 110 2.3E-38 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily HL41_01400 34eca3d704ca2ee9c75bc0ee8e7b6d31 112 PIRSF PIRSF004555 5 109 2.7E-37 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 SUPERFAMILY SSF52943 3 290 2.62E-84 T 14-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 290 1.8E-96 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 PRINTS PR00126 ATP synthase gamma subunit signature 268 289 2.3E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 PRINTS PR00126 ATP synthase gamma subunit signature 237 256 2.3E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 PRINTS PR00126 ATP synthase gamma subunit signature 75 94 2.3E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 2.3E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 290 33.171 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 276 289 - T 14-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 Gene3D G3DSA:1.10.287.80 6 286 1.7E-94 T 14-10-2018 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 Gene3D G3DSA:3.40.1380.10 63 209 1.7E-94 T 14-10-2018 HL41_01090 f33ad614fe935ac447d2c2ec35e9c96b 293 Pfam PF00231 ATP synthase 3 289 2.6E-93 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_05825 143bc8b5e67b412c4b03b45d44ddc18d 187 Gene3D G3DSA:3.40.50.850 5 187 7.1E-46 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 HL41_05825 143bc8b5e67b412c4b03b45d44ddc18d 187 SUPERFAMILY SSF52499 1 186 1.57E-46 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 HL41_05825 143bc8b5e67b412c4b03b45d44ddc18d 187 Pfam PF00857 Isochorismatase family 14 152 7.9E-29 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 HL41_04985 a3e338e41849e7fdc1f1e3bccc97e096 153 Gene3D G3DSA:1.10.10.2890 14 70 1.5E-23 T 14-10-2018 HL41_04985 a3e338e41849e7fdc1f1e3bccc97e096 153 Gene3D G3DSA:3.30.70.3460 71 124 1.5E-23 T 14-10-2018 HL41_04985 a3e338e41849e7fdc1f1e3bccc97e096 153 SUPERFAMILY SSF46785 14 71 1.63E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_08985 2bdc9f9c8798e0891e8804d2c3fcaf6c 240 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 140 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_08985 2bdc9f9c8798e0891e8804d2c3fcaf6c 240 PIRSF PIRSF002155 1 228 1.6E-81 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_08985 2bdc9f9c8798e0891e8804d2c3fcaf6c 240 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 230 43.94 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HL41_08985 2bdc9f9c8798e0891e8804d2c3fcaf6c 240 Gene3D G3DSA:3.30.190.20 21 226 2.6E-87 T 14-10-2018 HL41_08985 2bdc9f9c8798e0891e8804d2c3fcaf6c 240 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 229 6.3E-104 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HL41_08985 2bdc9f9c8798e0891e8804d2c3fcaf6c 240 Gene3D G3DSA:3.40.50.790 68 160 2.6E-87 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich HL41_08985 2bdc9f9c8798e0891e8804d2c3fcaf6c 240 SUPERFAMILY SSF56808 6 228 5.62E-85 T 14-10-2018 IPR023674 Ribosomal protein L1-like HL41_08985 2bdc9f9c8798e0891e8804d2c3fcaf6c 240 Pfam PF00687 Ribosomal protein L1p/L10e family 33 221 2.6E-57 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein HL41_02020 e4c225c39184fc55a016c358294c1b5d 285 SUPERFAMILY SSF52317 6 148 6.41E-20 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_02020 e4c225c39184fc55a016c358294c1b5d 285 Pfam PF02016 LD-carboxypeptidase 7 272 1.5E-49 T 14-10-2018 IPR003507 Peptidase family S66 HL41_02020 e4c225c39184fc55a016c358294c1b5d 285 Gene3D G3DSA:3.50.30.60 138 284 3.5E-27 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily HL41_02020 e4c225c39184fc55a016c358294c1b5d 285 SUPERFAMILY SSF141986 134 274 3.4E-30 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily HL41_02020 e4c225c39184fc55a016c358294c1b5d 285 Gene3D G3DSA:3.40.50.10740 2 137 1.0E-17 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal HL41_02020 e4c225c39184fc55a016c358294c1b5d 285 PIRSF PIRSF028757 1 285 1.4E-48 T 14-10-2018 IPR003507 Peptidase family S66 HL41_07640 4126fc5f3b9b9a8c2e7fc7aa6cdf07ed 222 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 111 205 6.0E-35 T 14-10-2018 IPR022026 Methylene-tetrahydrofolate reductase C-terminal HL41_07240 98ccec9922ad1c193a8f4545ae60c77c 230 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 2 191 2.7E-51 T 14-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein HL41_07240 98ccec9922ad1c193a8f4545ae60c77c 230 Gene3D G3DSA:3.20.20.70 1 225 1.7E-32 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_07240 98ccec9922ad1c193a8f4545ae60c77c 230 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 14-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 HL41_07240 98ccec9922ad1c193a8f4545ae60c77c 230 SUPERFAMILY SSF102114 14 180 1.01E-22 T 14-10-2018 HL41_07240 98ccec9922ad1c193a8f4545ae60c77c 230 Pfam PF04055 Radical SAM superfamily 20 176 3.8E-19 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_07240 98ccec9922ad1c193a8f4545ae60c77c 230 SMART SM00729 16 219 4.7E-4 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_07240 98ccec9922ad1c193a8f4545ae60c77c 230 Pfam PF13353 4Fe-4S single cluster domain 15 110 5.5E-13 T 14-10-2018 HL41_01565 078015a53dc581dc3f631fc3120ccc9e 346 Gene3D G3DSA:3.40.50.720 2 334 1.1E-101 T 14-10-2018 HL41_01565 078015a53dc581dc3f631fc3120ccc9e 346 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 152 179 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 HL41_01565 078015a53dc581dc3f631fc3120ccc9e 346 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 311 7.3E-52 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HL41_01565 078015a53dc581dc3f631fc3120ccc9e 346 SUPERFAMILY SSF52283 22 136 8.51E-25 T 14-10-2018 HL41_01565 078015a53dc581dc3f631fc3120ccc9e 346 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 337 8.8E-24 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 HL41_01565 078015a53dc581dc3f631fc3120ccc9e 346 Gene3D G3DSA:3.40.50.720 107 311 1.1E-101 T 14-10-2018 HL41_01565 078015a53dc581dc3f631fc3120ccc9e 346 SUPERFAMILY SSF51735 109 311 4.16E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_04725 2727708e46cff662e59800842030e9a3 866 Gene3D G3DSA:3.10.310.40 757 865 1.5E-15 T 14-10-2018 HL41_04725 2727708e46cff662e59800842030e9a3 866 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 646 689 1.2E-20 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HL41_04725 2727708e46cff662e59800842030e9a3 866 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 866 173.032 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 HL41_04725 2727708e46cff662e59800842030e9a3 866 Gene3D G3DSA:3.30.980.10 549 688 1.7E-55 T 14-10-2018 HL41_04725 2727708e46cff662e59800842030e9a3 866 SMART SM00863 646 689 1.8E-23 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HL41_04725 2727708e46cff662e59800842030e9a3 866 SUPERFAMILY SSF55681 4 245 1.49E-111 T 14-10-2018 HL41_04725 2727708e46cff662e59800842030e9a3 866 Gene3D G3DSA:3.30.930.10 2 242 1.0E-116 T 14-10-2018 HL41_04725 2727708e46cff662e59800842030e9a3 866 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 844 4.2E-299 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HL41_04725 2727708e46cff662e59800842030e9a3 866 Pfam PF02272 DHHA1 domain 726 862 2.3E-10 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HL41_04725 2727708e46cff662e59800842030e9a3 866 SUPERFAMILY SSF101353 246 462 7.19E-65 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 HL41_04725 2727708e46cff662e59800842030e9a3 866 Gene3D G3DSA:3.30.54.20 617 670 1.7E-55 T 14-10-2018 HL41_04725 2727708e46cff662e59800842030e9a3 866 Pfam PF01411 tRNA synthetases class II (A) 5 549 3.5E-214 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 HL41_04725 2727708e46cff662e59800842030e9a3 866 Gene3D G3DSA:2.40.30.130 446 545 2.2E-12 T 14-10-2018 HL41_04725 2727708e46cff662e59800842030e9a3 866 SUPERFAMILY SSF55186 545 703 1.96E-55 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 HL41_04725 2727708e46cff662e59800842030e9a3 866 SUPERFAMILY SSF50447 457 545 4.59E-17 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_04725 2727708e46cff662e59800842030e9a3 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 2.7E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HL41_04725 2727708e46cff662e59800842030e9a3 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 2.7E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HL41_04725 2727708e46cff662e59800842030e9a3 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 2.7E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HL41_04725 2727708e46cff662e59800842030e9a3 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 2.7E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HL41_04725 2727708e46cff662e59800842030e9a3 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 2.7E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HL41_00925 91484c9f4424809d6748f14b726024a3 215 Gene3D G3DSA:3.20.20.140 2 210 3.8E-24 T 14-10-2018 HL41_00925 91484c9f4424809d6748f14b726024a3 215 Pfam PF02811 PHP domain 3 74 4.0E-7 T 14-10-2018 IPR004013 PHP domain GO:0003824 HL41_00925 91484c9f4424809d6748f14b726024a3 215 SUPERFAMILY SSF89550 10 211 1.96E-40 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HL41_00925 91484c9f4424809d6748f14b726024a3 215 SMART SM00481 2 74 6.9E-15 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HL41_08530 bca61d451d14b2794088828c03f83aa1 565 Gene3D G3DSA:3.40.50.800 4 545 5.9E-247 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily HL41_08530 bca61d451d14b2794088828c03f83aa1 565 PIRSF PIRSF001535 1 564 2.0E-255 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 Gene3D G3DSA:3.30.930.10 11 461 5.9E-247 T 14-10-2018 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 SUPERFAMILY SSF52954 459 560 1.36E-27 T 14-10-2018 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 562 40.768 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 SUPERFAMILY SSF55826 218 384 3.01E-35 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 Pfam PF04073 Aminoacyl-tRNA editing domain 257 371 1.8E-33 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 SUPERFAMILY SSF55681 9 474 4.98E-100 T 14-10-2018 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 4.0E-19 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 4.0E-19 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 4.0E-19 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 4.0E-19 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 Gene3D G3DSA:3.90.960.10 240 385 5.9E-247 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 5.8E-47 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 557 3.1E-214 T 14-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HL41_08530 bca61d451d14b2794088828c03f83aa1 565 Pfam PF03129 Anticodon binding domain 471 558 4.7E-17 T 14-10-2018 IPR004154 Anticodon-binding HL41_04850 d380561b0d6b6336142b527d0b364b74 237 Gene3D G3DSA:3.60.15.10 1 235 3.4E-53 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_04850 d380561b0d6b6336142b527d0b364b74 237 SUPERFAMILY SSF56281 8 230 9.85E-30 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_04850 d380561b0d6b6336142b527d0b364b74 237 SMART SM00849 22 205 1.3E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_04850 d380561b0d6b6336142b527d0b364b74 237 Pfam PF00753 Metallo-beta-lactamase superfamily 24 80 4.6E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_05170 ac9a3a320207057f8dfcd3d2ed2e8285 306 Gene3D G3DSA:1.10.20.140 112 181 5.5E-101 T 14-10-2018 HL41_05170 ac9a3a320207057f8dfcd3d2ed2e8285 306 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 7 290 9.1E-95 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 HL41_05170 ac9a3a320207057f8dfcd3d2ed2e8285 306 SUPERFAMILY SSF52540 7 151 2.95E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05170 ac9a3a320207057f8dfcd3d2ed2e8285 306 SUPERFAMILY SSF52540 6 287 2.81E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05170 ac9a3a320207057f8dfcd3d2ed2e8285 306 Gene3D G3DSA:3.40.50.300 9 286 5.5E-101 T 14-10-2018 HL41_05170 ac9a3a320207057f8dfcd3d2ed2e8285 306 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 5 296 30.022 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 HL41_05170 ac9a3a320207057f8dfcd3d2ed2e8285 306 Pfam PF01715 IPP transferase 38 282 5.3E-82 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Gene3D G3DSA:1.10.1790.20 1117 1295 4.8E-68 T 14-10-2018 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Pfam PF04997 RNA polymerase Rpb1, domain 1 16 342 1.0E-85 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 14 1350 18.812 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Gene3D G3DSA:1.10.40.90 374 416 1.7E-19 T 14-10-2018 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Gene3D G3DSA:2.40.50.100 935 1009 2.4E-22 T 14-10-2018 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Gene3D G3DSA:2.40.50.100 1133 1196 4.8E-68 T 14-10-2018 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Gene3D G3DSA:2.40.50.100 1010 1108 1.1E-30 T 14-10-2018 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Pfam PF00623 RNA polymerase Rpb1, domain 2 390 484 2.1E-24 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 381 7.8E-8 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Pfam PF05000 RNA polymerase Rpb1, domain 4 660 750 5.1E-18 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Gene3D G3DSA:1.10.150.390 1297 1351 7.8E-28 T 14-10-2018 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 629 3.0E-27 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Pfam PF04998 RNA polymerase Rpb1, domain 5 753 1293 9.1E-72 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Gene3D G3DSA:1.10.274.100 490 551 4.2E-25 T 14-10-2018 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 SMART SM00663 235 514 1.3E-163 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Gene3D G3DSA:1.10.132.30 628 777 4.3E-63 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 SUPERFAMILY SSF64484 15 1344 0.0 T 14-10-2018 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 Gene3D G3DSA:1.10.274.100 552 627 4.6E-19 T 14-10-2018 HL41_09005 f7ec3ba9c3624702ced2715e285a8ae3 1353 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 20 1348 0.0 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_07100 9a72d937463612829c2079c75ac38eb2 421 Gene3D G3DSA:3.40.50.11780 164 258 1.8E-6 T 14-10-2018 HL41_07100 9a72d937463612829c2079c75ac38eb2 421 Pfam PF17482 Phage tail sheath C-terminal domain 314 410 1.2E-6 T 14-10-2018 IPR020287 Tail sheath protein, C-terminal domain HL41_07100 9a72d937463612829c2079c75ac38eb2 421 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 132 305 4.3E-24 T 14-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 179 3.8E-20 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 341 505 5.4E-38 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 SMART SM00283 278 539 4.0E-63 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 376 403 3.4E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 299 328 3.4E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 405 434 3.4E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 SUPERFAMILY SSF58104 231 540 8.63E-67 T 14-10-2018 HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 Pfam PF00672 HAMP domain 212 259 6.6E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 Gene3D G3DSA:1.10.287.950 210 540 5.7E-69 T 14-10-2018 HL41_02950 b473fd82fdaf263077cea4af8c03df00 540 SMART SM00304 211 263 8.8E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HL41_07280 5d869b96a1d25cb6a05311fec66c5931 143 Gene3D G3DSA:3.30.1330.80 3 143 1.2E-45 T 14-10-2018 HL41_07280 5d869b96a1d25cb6a05311fec66c5931 143 PIRSF PIRSF016702 1 143 3.7E-44 T 14-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif HL41_07280 5d869b96a1d25cb6a05311fec66c5931 143 SUPERFAMILY SSF117856 5 141 3.92E-35 T 14-10-2018 HL41_07280 5d869b96a1d25cb6a05311fec66c5931 143 Pfam PF03479 Domain of unknown function (DUF296) 12 121 3.2E-20 T 14-10-2018 IPR005175 PPC domain HL41_02620 04379c718efdf5039a66d8cb248d8cb7 89 PIRSF PIRSF004669 1 89 8.8E-32 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HL41_02620 04379c718efdf5039a66d8cb248d8cb7 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.2E-22 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HL41_02620 04379c718efdf5039a66d8cb248d8cb7 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.2E-22 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HL41_02620 04379c718efdf5039a66d8cb248d8cb7 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.2E-22 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HL41_02620 04379c718efdf5039a66d8cb248d8cb7 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 2.2E-28 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HL41_02620 04379c718efdf5039a66d8cb248d8cb7 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 88 1.1E-30 T 14-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 474 1.6E-168 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 455 2.5E-200 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 SUPERFAMILY SSF51412 4 478 4.71E-128 T 14-10-2018 HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 Pfam PF00571 CBS domain 93 141 6.5E-12 T 14-10-2018 IPR000644 CBS domain HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 Pfam PF00571 CBS domain 150 201 1.6E-8 T 14-10-2018 IPR000644 CBS domain HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 487 86.068 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 PIRSF PIRSF000130 1 489 2.4E-217 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 SUPERFAMILY SSF54631 67 203 2.4E-33 T 14-10-2018 HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 Gene3D G3DSA:3.20.20.70 2 487 3.7E-226 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 SMART SM00116 158 206 7.9E-8 T 14-10-2018 IPR000644 CBS domain HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 SMART SM00116 96 145 8.1E-12 T 14-10-2018 IPR000644 CBS domain HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 295 307 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 HL41_06665 2f507c7d37963a651ad2ef8db4859679 489 SMART SM01240 7 474 0.0 T 14-10-2018 HL41_07570 ebef93cba92173d587bbe37b56cd4ba0 380 Pfam PF08495 FIST N domain 74 220 3.8E-7 T 14-10-2018 IPR013702 FIST domain, N-terminal HL41_07570 ebef93cba92173d587bbe37b56cd4ba0 380 Pfam PF10442 FIST C domain 262 358 3.6E-13 T 14-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 HL41_07570 ebef93cba92173d587bbe37b56cd4ba0 380 SMART SM01204 225 359 1.1E-5 T 14-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 HL41_01355 7cfdaa942bf0c1c7580f820a94c0bbea 245 Gene3D G3DSA:3.40.1180.10 2 242 9.0E-100 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 HL41_01355 7cfdaa942bf0c1c7580f820a94c0bbea 245 SUPERFAMILY SSF64005 10 236 1.57E-88 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 HL41_01355 7cfdaa942bf0c1c7580f820a94c0bbea 245 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 13 241 40.651 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HL41_01355 7cfdaa942bf0c1c7580f820a94c0bbea 245 Pfam PF01255 Putative undecaprenyl diphosphate synthase 20 240 3.9E-84 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HL41_01355 7cfdaa942bf0c1c7580f820a94c0bbea 245 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 13 240 8.3E-90 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HL41_00425 ed8ca6c02932ec24d5a36b4d0a357cc3 690 SUPERFAMILY SSF51230 593 668 7.2E-16 T 14-10-2018 IPR011053 Single hybrid motif HL41_00425 ed8ca6c02932ec24d5a36b4d0a357cc3 690 Gene3D G3DSA:2.40.50.100 597 669 3.1E-20 T 14-10-2018 HL41_00425 ed8ca6c02932ec24d5a36b4d0a357cc3 690 Pfam PF02436 Conserved carboxylase domain 314 549 1.5E-43 T 14-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 HL41_00425 ed8ca6c02932ec24d5a36b4d0a357cc3 690 Pfam PF00682 HMGL-like 26 284 1.5E-11 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HL41_00425 ed8ca6c02932ec24d5a36b4d0a357cc3 690 Pfam PF00364 Biotin-requiring enzyme 596 668 1.1E-12 T 14-10-2018 IPR000089 Biotin/lipoyl attachment HL41_00425 ed8ca6c02932ec24d5a36b4d0a357cc3 690 SUPERFAMILY SSF89000 319 532 2.59E-26 T 14-10-2018 HL41_00425 ed8ca6c02932ec24d5a36b4d0a357cc3 690 SUPERFAMILY SSF51569 23 310 9.82E-43 T 14-10-2018 HL41_00445 2d61c5d1589ab873da7f026bfe3aa13e 79 Hamap MF_00088 UPF0109 protein . 4 78 23.076 T 14-10-2018 IPR020627 Uncharacterised protein family UPF0109 HL41_00445 2d61c5d1589ab873da7f026bfe3aa13e 79 Pfam PF13083 KH domain 5 77 2.9E-23 T 14-10-2018 HL41_00445 2d61c5d1589ab873da7f026bfe3aa13e 79 Gene3D G3DSA:3.30.300.20 4 65 7.3E-6 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta HL41_00445 2d61c5d1589ab873da7f026bfe3aa13e 79 SUPERFAMILY SSF54814 18 64 1.37E-7 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 Gene3D G3DSA:3.90.640.10 231 296 4.5E-116 T 14-10-2018 HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 382 2.4E-122 T 14-10-2018 IPR020823 Cell division protein FtsA HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 Pfam PF14450 Cell division protein FtsA 203 378 4.4E-20 T 14-10-2018 HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 411 27.92 T 14-10-2018 IPR020823 Cell division protein FtsA HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 SMART SM00842 7 192 2.9E-79 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 Gene3D G3DSA:3.30.420.40 193 356 4.5E-116 T 14-10-2018 HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 Pfam PF02491 SHS2 domain inserted in FTSA 81 157 3.0E-26 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 PIRSF PIRSF003101 1 413 4.2E-134 T 14-10-2018 IPR020823 Cell division protein FtsA HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 Gene3D G3DSA:3.30.1490.110 83 165 4.5E-116 T 14-10-2018 HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 SUPERFAMILY SSF53067 194 382 1.3E-40 T 14-10-2018 HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 SUPERFAMILY SSF53067 7 193 3.64E-50 T 14-10-2018 HL41_04775 5269b2a675eba6bcf458c394a24f35a0 414 Gene3D G3DSA:3.30.420.40 10 376 4.5E-116 T 14-10-2018 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 80 2.3E-39 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 SUPERFAMILY SSF110324 2 80 2.41E-34 T 14-10-2018 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 PRINTS PR00063 Ribosomal protein L27 signature 4 28 5.2E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 PRINTS PR00063 Ribosomal protein L27 signature 29 53 5.2E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 PRINTS PR00063 Ribosomal protein L27 signature 54 78 5.2E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 28.81 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 Pfam PF01016 Ribosomal L27 protein 2 80 1.9E-39 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 82 1.0E-13 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01585 5d8ae60dcf88f033b88fe40d419c372f 84 Gene3D G3DSA:2.40.50.100 20 83 5.9E-29 T 14-10-2018 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 165 398 2.7E-86 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 Pfam PF02130 Uncharacterized protein family UPF0054 16 125 1.3E-26 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 165 398 3.1E-94 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 SUPERFAMILY SSF55486 18 146 7.08E-30 T 14-10-2018 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 Gene3D G3DSA:3.20.20.70 154 403 3.4E-99 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 162 403 103.153 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 SUPERFAMILY SSF63892 164 401 7.06E-90 T 14-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 38 142 1.2E-23 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 147 18.303 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HL41_00835 26fabbfb4b7d3939fe7beed40232b8d4 403 Gene3D G3DSA:3.40.390.30 1 151 5.8E-31 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 HL41_03300 53b1ee7a88fa30c1ad6a5edba4741da4 124 PIRSF PIRSF006113 1 124 1.9E-29 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 HL41_03300 53b1ee7a88fa30c1ad6a5edba4741da4 124 Gene3D G3DSA:3.30.479.10 1 123 7.4E-40 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 HL41_03300 53b1ee7a88fa30c1ad6a5edba4741da4 124 SUPERFAMILY SSF55620 1 123 6.12E-41 T 14-10-2018 HL41_03300 53b1ee7a88fa30c1ad6a5edba4741da4 124 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 95 2.0E-31 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 HL41_03300 53b1ee7a88fa30c1ad6a5edba4741da4 124 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 122 4.4E-40 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 HL41_07370 80efca45d824864dbf54263ceb004469 152 SUPERFAMILY SSF56770 10 145 1.44E-49 T 14-10-2018 HL41_07370 80efca45d824864dbf54263ceb004469 152 Gene3D G3DSA:3.40.50.12280 1 150 3.0E-50 T 14-10-2018 HL41_07370 80efca45d824864dbf54263ceb004469 152 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 28 137 2.7E-25 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08990 cd90f818395b571ee2f4e6252c95acb9 177 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 8 172 8.0E-6 T 14-10-2018 HL41_08990 cd90f818395b571ee2f4e6252c95acb9 177 Pfam PF00466 Ribosomal protein L10 5 101 9.0E-29 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 HL41_08990 cd90f818395b571ee2f4e6252c95acb9 177 SUPERFAMILY SSF160369 4 173 5.36E-52 T 14-10-2018 HL41_08990 cd90f818395b571ee2f4e6252c95acb9 177 Gene3D G3DSA:3.30.70.1730 4 134 5.6E-38 T 14-10-2018 HL41_08990 cd90f818395b571ee2f4e6252c95acb9 177 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 4 162 24.703 T 14-10-2018 IPR022973 Ribosomal protein L10 HL41_00260 671910a96f2500b3b8e0288669000815 160 Pfam PF05258 Protein of unknown function (DUF721) 21 81 6.7E-8 T 14-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 HL41_02925 d70e24377211cd38d91c66868c3f6f61 324 SUPERFAMILY SSF51735 1 321 4.41E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_02925 d70e24377211cd38d91c66868c3f6f61 324 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 247 3.4E-44 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HL41_02925 d70e24377211cd38d91c66868c3f6f61 324 Gene3D G3DSA:3.40.50.720 7 315 1.0E-125 T 14-10-2018 HL41_02925 d70e24377211cd38d91c66868c3f6f61 324 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 6 320 3.2E-127 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 HL41_02925 d70e24377211cd38d91c66868c3f6f61 324 Gene3D G3DSA:3.90.25.10 172 302 1.0E-125 T 14-10-2018 HL41_02925 d70e24377211cd38d91c66868c3f6f61 324 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 5 321 48.78 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 HL41_04010 ba7c31033919616688615b5808ef117b 432 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 15 107 2.1E-11 T 14-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 HL41_04010 ba7c31033919616688615b5808ef117b 432 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 219 410 5.0E-9 T 14-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 HL41_08355 098651c591e07fbeb6db5014c0677878 280 Gene3D G3DSA:3.30.950.10 117 231 7.0E-28 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 HL41_08355 098651c591e07fbeb6db5014c0677878 280 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 8 224 31.813 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 HL41_08355 098651c591e07fbeb6db5014c0677878 280 SUPERFAMILY SSF53790 6 221 5.89E-67 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 HL41_08355 098651c591e07fbeb6db5014c0677878 280 Gene3D G3DSA:3.40.1010.10 1 116 2.7E-40 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 HL41_08355 098651c591e07fbeb6db5014c0677878 280 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 8 277 8.6E-67 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 HL41_08355 098651c591e07fbeb6db5014c0677878 280 PIRSF PIRSF005917 1 280 3.0E-85 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 HL41_08355 098651c591e07fbeb6db5014c0677878 280 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 208 1.9E-32 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 SUPERFAMILY SSF53335 71 253 5.63E-49 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_02555 7776040a21ab7e1366e73b645d56918f 273 Gene3D G3DSA:3.40.50.150 70 272 4.9E-61 T 14-10-2018 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 Gene3D G3DSA:1.10.155.10 1 69 4.3E-7 T 14-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily HL41_02555 7776040a21ab7e1366e73b645d56918f 273 SUPERFAMILY SSF47757 2 70 1.57E-11 T 14-10-2018 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 Pfam PF03705 CheR methyltransferase, all-alpha domain 5 55 1.5E-8 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HL41_02555 7776040a21ab7e1366e73b645d56918f 273 PRINTS PR00996 Glutamate methyltransferase family signature 64 76 1.6E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 PRINTS PR00996 Glutamate methyltransferase family signature 104 124 1.6E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 PRINTS PR00996 Glutamate methyltransferase family signature 228 251 1.6E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 PRINTS PR00996 Glutamate methyltransferase family signature 25 38 1.6E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 PRINTS PR00996 Glutamate methyltransferase family signature 140 156 1.6E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 PRINTS PR00996 Glutamate methyltransferase family signature 209 223 1.6E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 SMART SM00138 3 271 3.4E-93 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HL41_02555 7776040a21ab7e1366e73b645d56918f 273 Pfam PF01739 CheR methyltransferase, SAM binding domain 71 262 3.5E-62 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal HL41_02370 34af2f37dfb77a30f2b73b115123ade1 149 Gene3D G3DSA:1.10.10.10 9 87 1.4E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_02370 34af2f37dfb77a30f2b73b115123ade1 149 SUPERFAMILY SSF46785 13 145 6.67E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_02370 34af2f37dfb77a30f2b73b115123ade1 149 Gene3D G3DSA:3.30.1490.190 92 149 9.4E-16 T 14-10-2018 HL41_02370 34af2f37dfb77a30f2b73b115123ade1 149 Pfam PF01475 Ferric uptake regulator family 16 140 6.1E-31 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HL41_06135 55dab2400a4958cb8d0a52fc655384cd 171 SUPERFAMILY SSF56770 21 164 1.57E-69 T 14-10-2018 HL41_06135 55dab2400a4958cb8d0a52fc655384cd 171 Gene3D G3DSA:3.40.50.12280 10 170 1.6E-78 T 14-10-2018 HL41_06135 55dab2400a4958cb8d0a52fc655384cd 171 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 22 163 7.7E-74 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06135 55dab2400a4958cb8d0a52fc655384cd 171 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 48 156 6.4E-28 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06135 55dab2400a4958cb8d0a52fc655384cd 171 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 6 161 43.405 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_01290 0c084bb347993291a265a4a1bd181617 65 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 2.8E-25 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01290 0c084bb347993291a265a4a1bd181617 65 Pfam PF00830 Ribosomal L28 family 3 59 6.1E-25 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01290 0c084bb347993291a265a4a1bd181617 65 Gene3D G3DSA:2.30.170.40 19 65 1.9E-22 T 14-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01290 0c084bb347993291a265a4a1bd181617 65 SUPERFAMILY SSF143800 1 63 3.92E-26 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01290 0c084bb347993291a265a4a1bd181617 65 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 20.102 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 Pfam PF05746 DALR anticodon binding domain 429 549 8.6E-33 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 SMART SM01016 3 87 1.9E-29 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 126 135 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 131 147 5.9E-25 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 155 168 5.9E-25 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 116 131 5.9E-25 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 5.9E-25 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 SMART SM00836 429 549 4.7E-54 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 SUPERFAMILY SSF47323 424 549 2.42E-36 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 3 86 1.5E-22 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 Pfam PF00750 tRNA synthetases class I (R) 100 397 1.9E-34 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 Gene3D G3DSA:1.10.730.10 424 549 9.6E-181 T 14-10-2018 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 SUPERFAMILY SSF52374 110 439 1.42E-98 T 14-10-2018 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 549 28.142 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 SUPERFAMILY SSF55190 2 107 2.09E-19 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 1 549 3.8E-151 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 Gene3D G3DSA:3.40.50.620 116 423 9.6E-181 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_01185 dd36c5bb5e9410687607520dae75fc2f 549 Gene3D G3DSA:3.30.1360.70 1 112 2.8E-25 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HL41_07970 ff1b02fd8451d1b086a2fdd9917325fe 359 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 12 353 8.8E-119 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HL41_07970 ff1b02fd8451d1b086a2fdd9917325fe 359 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 355 64.869 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HL41_07970 ff1b02fd8451d1b086a2fdd9917325fe 359 SUPERFAMILY SSF56796 3 356 8.5E-104 T 14-10-2018 HL41_07970 ff1b02fd8451d1b086a2fdd9917325fe 359 Pfam PF01761 3-dehydroquinate synthase 67 324 9.5E-101 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HL41_07970 ff1b02fd8451d1b086a2fdd9917325fe 359 Gene3D G3DSA:3.40.50.1970 1 172 3.3E-63 T 14-10-2018 HL41_07970 ff1b02fd8451d1b086a2fdd9917325fe 359 Gene3D G3DSA:1.20.1090.10 173 359 5.0E-61 T 14-10-2018 HL41_07970 ff1b02fd8451d1b086a2fdd9917325fe 359 PIRSF PIRSF001455 4 358 2.8E-115 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HL41_07295 5adb13a9ec8758b3dd66ff7cc5ef768d 429 Gene3D G3DSA:3.30.70.3270 2 98 1.9E-7 T 14-10-2018 HL41_07295 5adb13a9ec8758b3dd66ff7cc5ef768d 429 PIRSF PIRSF000139 6 429 6.5E-102 T 14-10-2018 HL41_07295 5adb13a9ec8758b3dd66ff7cc5ef768d 429 Pfam PF13183 4Fe-4S dicluster domain 16 83 1.6E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_07295 5adb13a9ec8758b3dd66ff7cc5ef768d 429 Pfam PF02754 Cysteine-rich domain 187 268 5.8E-17 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_07295 5adb13a9ec8758b3dd66ff7cc5ef768d 429 Pfam PF02754 Cysteine-rich domain 317 401 8.5E-18 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_07295 5adb13a9ec8758b3dd66ff7cc5ef768d 429 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 69 80 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07295 5adb13a9ec8758b3dd66ff7cc5ef768d 429 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 19 30 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07295 5adb13a9ec8758b3dd66ff7cc5ef768d 429 SUPERFAMILY SSF46548 13 98 8.02E-16 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_08815 13ec24e59b9c4df7f879986237842961 226 TIGRFAM TIGR02252 DREG-2: HAD hydrolase, REG-2-like, family IA 6 202 3.3E-46 T 14-10-2018 IPR011949 HAD-superfamily hydrolase, subfamily IA, REG-2-like HL41_08815 13ec24e59b9c4df7f879986237842961 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 203 2.4E-21 T 14-10-2018 HL41_08815 13ec24e59b9c4df7f879986237842961 226 Gene3D G3DSA:3.40.50.1000 6 204 6.2E-47 T 14-10-2018 IPR023214 HAD superfamily HL41_08815 13ec24e59b9c4df7f879986237842961 226 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 112 200 3.1E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HL41_08815 13ec24e59b9c4df7f879986237842961 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 3.6E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HL41_08815 13ec24e59b9c4df7f879986237842961 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 167 187 3.6E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HL41_08815 13ec24e59b9c4df7f879986237842961 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 165 3.6E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HL41_08815 13ec24e59b9c4df7f879986237842961 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 119 132 3.6E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HL41_08815 13ec24e59b9c4df7f879986237842961 226 SUPERFAMILY SSF56784 4 209 3.53E-39 T 14-10-2018 IPR036412 HAD-like superfamily HL41_08815 13ec24e59b9c4df7f879986237842961 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 117 206 2.4E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HL41_08815 13ec24e59b9c4df7f879986237842961 226 Gene3D G3DSA:1.10.150.720 21 101 6.2E-47 T 14-10-2018 HL41_05715 e54031a9ef2e77fc1bd6efed572cec3b 82 SMART SM00834 1 43 1.8E-13 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_05715 e54031a9ef2e77fc1bd6efed572cec3b 82 Pfam PF09723 Zinc ribbon domain 1 42 2.0E-13 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_05715 e54031a9ef2e77fc1bd6efed572cec3b 82 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 1.0E-15 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_07985 c5680df44d29128991465c7ac2064748 210 Gene3D G3DSA:3.40.50.360 1 206 1.3E-41 T 14-10-2018 IPR029039 Flavoprotein-like superfamily HL41_07985 c5680df44d29128991465c7ac2064748 210 Pfam PF03358 NADPH-dependent FMN reductase 1 153 3.2E-35 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HL41_07985 c5680df44d29128991465c7ac2064748 210 SUPERFAMILY SSF52218 1 188 4.04E-46 T 14-10-2018 IPR029039 Flavoprotein-like superfamily HL41_01815 b929410b5a1f17c13e8710b81d978751 465 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HL41_01815 b929410b5a1f17c13e8710b81d978751 465 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 169 182 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 SUPERFAMILY SSF46689 413 459 3.49E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 Gene3D G3DSA:3.40.50.2300 6 124 3.0E-36 T 14-10-2018 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 Gene3D G3DSA:1.10.10.60 418 459 1.1E-14 T 14-10-2018 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 Pfam PF02954 Bacterial regulatory protein, Fis family 418 458 4.2E-14 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 Pfam PF00072 Response regulator receiver domain 7 111 1.7E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 SUPERFAMILY SSF52172 5 189 1.15E-38 T 14-10-2018 IPR011006 CheY-like superfamily HL41_01815 b929410b5a1f17c13e8710b81d978751 465 Pfam PF00158 Sigma-54 interaction domain 146 311 1.8E-65 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 SMART SM00448 5 114 4.1E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 Gene3D G3DSA:1.10.8.60 316 393 1.9E-27 T 14-10-2018 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 Gene3D G3DSA:3.40.50.300 132 315 1.0E-61 T 14-10-2018 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 SUPERFAMILY SSF52540 145 387 6.76E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01815 b929410b5a1f17c13e8710b81d978751 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 424 441 1.4E-8 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 441 461 1.4E-8 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_01815 b929410b5a1f17c13e8710b81d978751 465 SMART SM00382 165 312 1.0E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_02105 90b8cb699f0c4330f6ef19e7996689b2 473 SUPERFAMILY SSF103473 8 463 4.05E-61 T 14-10-2018 IPR036259 MFS transporter superfamily HL41_02105 90b8cb699f0c4330f6ef19e7996689b2 473 Gene3D G3DSA:1.20.1720.10 14 260 1.9E-42 T 14-10-2018 HL41_02105 90b8cb699f0c4330f6ef19e7996689b2 473 Pfam PF07690 Major Facilitator Superfamily 20 413 1.6E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HL41_02105 90b8cb699f0c4330f6ef19e7996689b2 473 Gene3D G3DSA:1.20.1250.20 261 465 5.7E-19 T 14-10-2018 HL41_08830 ac899a34da125b3244396c42536c29a6 441 Pfam PF00206 Lyase 26 292 6.2E-56 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal HL41_08830 ac899a34da125b3244396c42536c29a6 441 PRINTS PR00145 Argininosuccinate lyase family signature 97 119 1.4E-10 T 14-10-2018 HL41_08830 ac899a34da125b3244396c42536c29a6 441 PRINTS PR00145 Argininosuccinate lyase family signature 271 287 1.4E-10 T 14-10-2018 HL41_08830 ac899a34da125b3244396c42536c29a6 441 PRINTS PR00145 Argininosuccinate lyase family signature 226 250 1.4E-10 T 14-10-2018 HL41_08830 ac899a34da125b3244396c42536c29a6 441 PRINTS PR00145 Argininosuccinate lyase family signature 138 158 1.4E-10 T 14-10-2018 HL41_08830 ac899a34da125b3244396c42536c29a6 441 SMART SM00998 359 440 7.6E-35 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_08830 ac899a34da125b3244396c42536c29a6 441 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 1.5E-27 T 14-10-2018 IPR000362 Fumarate lyase family HL41_08830 ac899a34da125b3244396c42536c29a6 441 PRINTS PR00149 Fumarate lyase superfamily signature 226 253 1.5E-27 T 14-10-2018 IPR000362 Fumarate lyase family HL41_08830 ac899a34da125b3244396c42536c29a6 441 PRINTS PR00149 Fumarate lyase superfamily signature 271 287 1.5E-27 T 14-10-2018 IPR000362 Fumarate lyase family HL41_08830 ac899a34da125b3244396c42536c29a6 441 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 1.5E-27 T 14-10-2018 IPR000362 Fumarate lyase family HL41_08830 ac899a34da125b3244396c42536c29a6 441 Gene3D G3DSA:1.10.275.10 1 102 1.9E-28 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal HL41_08830 ac899a34da125b3244396c42536c29a6 441 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 440 3.6E-163 T 14-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_08830 ac899a34da125b3244396c42536c29a6 441 Gene3D G3DSA:1.10.40.30 359 439 5.4E-32 T 14-10-2018 HL41_08830 ac899a34da125b3244396c42536c29a6 441 Gene3D G3DSA:1.20.200.10 103 357 5.0E-94 T 14-10-2018 HL41_08830 ac899a34da125b3244396c42536c29a6 441 Pfam PF10397 Adenylosuccinate lyase C-terminus 360 439 4.6E-26 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_08830 ac899a34da125b3244396c42536c29a6 441 SUPERFAMILY SSF48557 3 440 1.57E-131 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 HL41_08830 ac899a34da125b3244396c42536c29a6 441 ProSitePatterns PS00163 Fumarate lyases signature. 271 280 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Gene3D G3DSA:2.40.270.10 798 836 1.2E-6 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Pfam PF04563 RNA polymerase beta subunit 26 505 1.3E-25 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Pfam PF04565 RNA polymerase Rpb2, domain 3 520 587 6.6E-28 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Gene3D G3DSA:3.90.1100.10 348 634 5.7E-67 T 14-10-2018 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Gene3D G3DSA:2.40.270.10 1058 1262 2.2E-80 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Gene3D G3DSA:2.40.50.150 837 961 2.5E-48 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Pfam PF04560 RNA polymerase Rpb2, domain 7 1286 1360 3.8E-24 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 SUPERFAMILY SSF64484 11 1360 0.0 T 14-10-2018 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Gene3D G3DSA:3.90.1100.10 652 720 4.8E-19 T 14-10-2018 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Gene3D G3DSA:3.90.1100.10 17 173 8.0E-49 T 14-10-2018 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 12 1362 12.089 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 10 1358 0.0 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Gene3D G3DSA:2.40.50.100 721 797 1.3E-29 T 14-10-2018 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1087 1099 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Pfam PF04561 RNA polymerase Rpb2, domain 2 345 461 8.6E-16 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Pfam PF04561 RNA polymerase Rpb2, domain 2 156 254 1.1E-8 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Pfam PF00562 RNA polymerase Rpb2, domain 6 724 1284 2.2E-164 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Pfam PF10385 RNA polymerase beta subunit external 1 domain 598 661 3.3E-18 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HL41_09000 aba543007e30d0e51b383184a003f1c4 1362 Gene3D G3DSA:3.90.1800.10 1272 1325 1.4E-9 T 14-10-2018 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 31 40 3.4E-23 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 91 103 3.4E-23 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 221 231 3.4E-23 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 131 143 3.4E-23 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 153 165 3.4E-23 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 103 117 3.4E-23 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 35 231 9.0E-86 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 208 220 - T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 160 175 - T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 72 91 6.0E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 160 180 6.0E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 205 230 6.0E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 52 72 6.0E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 33 52 6.0E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 181 202 6.0E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HL41_02625 f9cc10035b1234809a84a6d58c996e6f 232 Pfam PF00813 FliP family 35 227 4.7E-80 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HL41_05605 2f80ddfe28c0fbef3dee65d60e08399e 168 Pfam PF02674 Colicin V production protein 4 145 2.1E-24 T 14-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 HL41_06965 89d765b0ef908f8f9ffe49da02cd36f5 75 Pfam PF12728 Helix-turn-helix domain 4 58 9.8E-12 T 14-10-2018 HL41_06965 89d765b0ef908f8f9ffe49da02cd36f5 75 SUPERFAMILY SSF46955 3 59 5.68E-8 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily HL41_06965 89d765b0ef908f8f9ffe49da02cd36f5 75 Gene3D G3DSA:1.10.1660.10 1 59 2.3E-11 T 14-10-2018 HL41_06965 89d765b0ef908f8f9ffe49da02cd36f5 75 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 56 1.3E-10 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 HL41_00580 d72fbb31123723bfbcef6be257d91bf5 137 Gene3D G3DSA:1.10.10.10 2 82 7.4E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_00580 d72fbb31123723bfbcef6be257d91bf5 137 Gene3D G3DSA:3.30.1490.190 84 137 2.9E-9 T 14-10-2018 HL41_00580 d72fbb31123723bfbcef6be257d91bf5 137 Pfam PF01475 Ferric uptake regulator family 13 113 1.1E-30 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HL41_00580 d72fbb31123723bfbcef6be257d91bf5 137 SUPERFAMILY SSF46785 5 131 1.42E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_04955 e864826dc5738bd5fcb0e7bdcc45e31c 428 Gene3D G3DSA:3.40.140.20 224 420 1.1E-43 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_04955 e864826dc5738bd5fcb0e7bdcc45e31c 428 Pfam PF01808 AICARFT/IMPCHase bienzyme 46 317 2.8E-61 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_04955 e864826dc5738bd5fcb0e7bdcc45e31c 428 Gene3D G3DSA:3.40.140.20 46 216 3.5E-46 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_04955 e864826dc5738bd5fcb0e7bdcc45e31c 428 SUPERFAMILY SSF53927 47 428 1.7E-102 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 HL41_04955 e864826dc5738bd5fcb0e7bdcc45e31c 428 PIRSF PIRSF000414 7 428 3.6E-105 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_04955 e864826dc5738bd5fcb0e7bdcc45e31c 428 SMART SM00798 11 319 5.8E-40 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_00815 942ba51b0e7e9c73aa2f81fb9b538260 135 SUPERFAMILY SSF118196 1 130 1.96E-38 T 14-10-2018 IPR036413 YaeB-like superfamily HL41_00815 942ba51b0e7e9c73aa2f81fb9b538260 135 Pfam PF01980 Uncharacterised protein family UPF0066 18 129 5.7E-32 T 14-10-2018 IPR023370 YaeB-like, N-terminal domain HL41_00815 942ba51b0e7e9c73aa2f81fb9b538260 135 Gene3D G3DSA:2.40.30.70 4 134 7.2E-38 T 14-10-2018 IPR036414 YaeB, N-terminal domain superfamily HL41_00815 942ba51b0e7e9c73aa2f81fb9b538260 135 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 2 130 3.3E-33 T 14-10-2018 IPR023370 YaeB-like, N-terminal domain HL41_04155 236a0e8061e519a34f5e921dc190c08d 167 Pfam PF00990 Diguanylate cyclase, GGDEF domain 9 160 1.4E-40 T 14-10-2018 IPR000160 GGDEF domain HL41_04155 236a0e8061e519a34f5e921dc190c08d 167 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 7 165 2.7E-45 T 14-10-2018 IPR000160 GGDEF domain HL41_04155 236a0e8061e519a34f5e921dc190c08d 167 Gene3D G3DSA:3.30.70.270 7 167 7.8E-48 T 14-10-2018 HL41_04155 236a0e8061e519a34f5e921dc190c08d 167 SUPERFAMILY SSF55073 13 164 3.61E-40 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_04155 236a0e8061e519a34f5e921dc190c08d 167 SMART SM00267 2 166 4.1E-41 T 14-10-2018 IPR000160 GGDEF domain HL41_05785 f5c84339dbe121d5c33b73637b0aea2a 442 Gene3D G3DSA:3.80.30.20 200 404 6.1E-17 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HL41_05785 f5c84339dbe121d5c33b73637b0aea2a 442 SUPERFAMILY SSF102114 182 402 1.96E-27 T 14-10-2018 HL41_05785 f5c84339dbe121d5c33b73637b0aea2a 442 SMART SM00729 202 411 6.6E-18 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_05785 f5c84339dbe121d5c33b73637b0aea2a 442 Pfam PF04055 Radical SAM superfamily 209 370 9.3E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_02275 0620285cf20b064e7c36a837b6ade1c3 457 Gene3D G3DSA:1.10.45.10 415 452 1.3E-9 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HL41_02275 0620285cf20b064e7c36a837b6ade1c3 457 Pfam PF02913 FAD linked oxidases, C-terminal domain 223 451 1.5E-47 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HL41_02275 0620285cf20b064e7c36a837b6ade1c3 457 Gene3D G3DSA:3.30.465.40 2 236 1.8E-70 T 14-10-2018 HL41_02275 0620285cf20b064e7c36a837b6ade1c3 457 SUPERFAMILY SSF56176 5 217 2.99E-69 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 HL41_02275 0620285cf20b064e7c36a837b6ade1c3 457 Gene3D G3DSA:3.30.70.2740 335 414 6.6E-16 T 14-10-2018 HL41_02275 0620285cf20b064e7c36a837b6ade1c3 457 Pfam PF01565 FAD binding domain 41 180 1.4E-40 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HL41_02275 0620285cf20b064e7c36a837b6ade1c3 457 SUPERFAMILY SSF55103 231 452 4.91E-48 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HL41_03030 3c4d359e55c7b9ec4b6c791f727e4db6 447 SUPERFAMILY SSF109755 8 219 1.36E-56 T 14-10-2018 HL41_03030 3c4d359e55c7b9ec4b6c791f727e4db6 447 Pfam PF01895 PhoU domain 123 206 4.7E-19 T 14-10-2018 IPR026022 PhoU domain HL41_03030 3c4d359e55c7b9ec4b6c791f727e4db6 447 Pfam PF01895 PhoU domain 17 103 1.1E-20 T 14-10-2018 IPR026022 PhoU domain HL41_03030 3c4d359e55c7b9ec4b6c791f727e4db6 447 Gene3D G3DSA:1.20.58.220 116 236 6.8E-32 T 14-10-2018 IPR038078 PhoU-like domain superfamily HL41_03030 3c4d359e55c7b9ec4b6c791f727e4db6 447 Gene3D G3DSA:1.20.58.220 2 114 6.0E-29 T 14-10-2018 IPR038078 PhoU-like domain superfamily HL41_03030 3c4d359e55c7b9ec4b6c791f727e4db6 447 Pfam PF01865 Protein of unknown function DUF47 233 446 3.0E-27 T 14-10-2018 IPR018445 Putative phosphate transport regulator HL41_03030 3c4d359e55c7b9ec4b6c791f727e4db6 447 Gene3D G3DSA:1.20.58.220 237 447 4.4E-35 T 14-10-2018 IPR038078 PhoU-like domain superfamily HL41_03030 3c4d359e55c7b9ec4b6c791f727e4db6 447 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 217 3.7E-54 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HL41_03030 3c4d359e55c7b9ec4b6c791f727e4db6 447 SUPERFAMILY SSF109755 247 442 3.23E-9 T 14-10-2018 HL41_05660 4192eda012502fb005a108371577ff36 165 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 5 79 4.0E-23 T 14-10-2018 HL41_05660 4192eda012502fb005a108371577ff36 165 Gene3D G3DSA:3.30.70.1150 84 160 8.7E-33 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal HL41_05660 4192eda012502fb005a108371577ff36 165 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 5 161 2.2E-61 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HL41_05660 4192eda012502fb005a108371577ff36 165 Pfam PF13710 ACT domain 15 76 9.7E-14 T 14-10-2018 HL41_05660 4192eda012502fb005a108371577ff36 165 Gene3D G3DSA:3.30.70.260 2 82 7.6E-33 T 14-10-2018 HL41_05660 4192eda012502fb005a108371577ff36 165 Pfam PF10369 Small subunit of acetolactate synthase 88 160 1.6E-32 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HL41_05660 4192eda012502fb005a108371577ff36 165 SUPERFAMILY SSF55021 83 163 7.94E-30 T 14-10-2018 HL41_05660 4192eda012502fb005a108371577ff36 165 SUPERFAMILY SSF55021 5 78 4.91E-21 T 14-10-2018 HL41_01540 bc818b2b0f2b9a4a6006a9d584f62e03 435 Pfam PF01979 Amidohydrolase family 57 405 3.7E-67 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HL41_01540 bc818b2b0f2b9a4a6006a9d584f62e03 435 Gene3D G3DSA:3.20.20.140 61 350 2.3E-140 T 14-10-2018 HL41_01540 bc818b2b0f2b9a4a6006a9d584f62e03 435 SUPERFAMILY SSF51556 60 352 3.32E-95 T 14-10-2018 IPR032466 Metal-dependent hydrolase HL41_01540 bc818b2b0f2b9a4a6006a9d584f62e03 435 Gene3D G3DSA:2.30.40.10 19 423 2.3E-140 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HL41_01540 bc818b2b0f2b9a4a6006a9d584f62e03 435 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 3 431 40.764 T 14-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 HL41_01540 bc818b2b0f2b9a4a6006a9d584f62e03 435 SUPERFAMILY SSF51338 6 430 3.46E-25 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 SMART SM00316 615 698 2.5E-8 T 14-10-2018 IPR022967 RNA-binding domain, S1 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 Gene3D G3DSA:2.40.50.140 619 696 7.2E-16 T 14-10-2018 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 SMART SM00357 73 129 7.4E-4 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 Pfam PF00773 RNB domain 244 571 9.0E-110 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 TIGRFAM TIGR02063 RNase_R: ribonuclease R 8 697 1.6E-236 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 Gene3D G3DSA:2.40.50.140 52 132 1.9E-14 T 14-10-2018 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 SUPERFAMILY SSF50249 615 691 2.61E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 59 690 1.4E-187 T 14-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 SUPERFAMILY SSF50249 122 219 1.3E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 SUPERFAMILY SSF50249 205 614 2.57E-139 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 Pfam PF08206 Ribonuclease B OB domain 74 128 1.4E-13 T 14-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 Hamap MF_01895 Ribonuclease R [rnr]. 25 698 54.843 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 Pfam PF00575 S1 RNA binding domain 613 695 1.6E-10 T 14-10-2018 IPR003029 S1 domain GO:0003676 HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 SUPERFAMILY SSF50249 55 131 2.51E-13 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_03380 3f7e2fae21fa86c35b29406b4ef1ef7a 698 SMART SM00955 244 572 3.5E-161 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 HL41_08905 552d91a36611c3ef8cecb7a5ff50c5af 457 Gene3D G3DSA:3.40.50.620 201 427 1.2E-67 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_08905 552d91a36611c3ef8cecb7a5ff50c5af 457 Pfam PF01747 ATP-sulfurylase 200 428 1.1E-73 T 14-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HL41_08905 552d91a36611c3ef8cecb7a5ff50c5af 457 SUPERFAMILY SSF52374 198 428 1.69E-63 T 14-10-2018 HL41_08905 552d91a36611c3ef8cecb7a5ff50c5af 457 SUPERFAMILY SSF88697 9 194 2.78E-30 T 14-10-2018 IPR015947 PUA-like superfamily HL41_08905 552d91a36611c3ef8cecb7a5ff50c5af 457 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 10 427 6.1E-132 T 14-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HL41_08905 552d91a36611c3ef8cecb7a5ff50c5af 457 Gene3D G3DSA:3.10.400.10 8 189 3.7E-27 T 14-10-2018 HL41_08905 552d91a36611c3ef8cecb7a5ff50c5af 457 Pfam PF14306 PUA-like domain 9 190 2.1E-32 T 14-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 HL41_05650 e13b30386e4fb8aa20a08cd604c7b704 74 Gene3D G3DSA:1.20.58.660 3 72 1.7E-6 T 14-10-2018 HL41_05650 e13b30386e4fb8aa20a08cd604c7b704 74 Pfam PF04325 Protein of unknown function (DUF465) 18 64 2.8E-8 T 14-10-2018 IPR007420 Protein of unknown function DUF465 HL41_03495 48776f5c1e4c413834eda02bf564b002 105 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 4 98 1.3E-16 T 14-10-2018 IPR002767 Thiamine-binding protein HL41_03495 48776f5c1e4c413834eda02bf564b002 105 SUPERFAMILY SSF89957 1 98 1.44E-25 T 14-10-2018 IPR029756 MTH1187/YkoF-like HL41_03495 48776f5c1e4c413834eda02bf564b002 105 Gene3D G3DSA:3.30.70.930 1 97 1.4E-27 T 14-10-2018 IPR029756 MTH1187/YkoF-like HL41_03495 48776f5c1e4c413834eda02bf564b002 105 Pfam PF01910 Thiamine-binding protein 6 95 5.7E-24 T 14-10-2018 IPR002767 Thiamine-binding protein HL41_06170 4ec294bc98ce830f16038bed5c1119d0 158 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 155 31.801 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_06170 4ec294bc98ce830f16038bed5c1119d0 158 SUPERFAMILY SSF52121 5 155 9.68E-65 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_06170 4ec294bc98ce830f16038bed5c1119d0 158 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 151 1.7E-60 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_06170 4ec294bc98ce830f16038bed5c1119d0 158 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 15 152 2.2E-61 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_06170 4ec294bc98ce830f16038bed5c1119d0 158 Gene3D G3DSA:3.40.50.960 3 156 1.1E-65 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HL41_05395 8ea31fdc55c53bf46928662556b97ab8 122 SMART SM01374 1 122 5.0E-91 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HL41_05395 8ea31fdc55c53bf46928662556b97ab8 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05395 8ea31fdc55c53bf46928662556b97ab8 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.656 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HL41_05395 8ea31fdc55c53bf46928662556b97ab8 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 6.6E-57 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HL41_05395 8ea31fdc55c53bf46928662556b97ab8 122 SUPERFAMILY SSF50193 1 122 1.15E-53 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05395 8ea31fdc55c53bf46928662556b97ab8 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 4.8E-60 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 HL41_05395 8ea31fdc55c53bf46928662556b97ab8 122 Gene3D G3DSA:2.40.150.20 1 122 3.2E-56 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 HL41_03570 a7834c25e4b52ccdb12897ab0627b700 290 Pfam PF03668 P-loop ATPase protein family 3 288 1.3E-83 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 HL41_03570 a7834c25e4b52ccdb12897ab0627b700 290 SUPERFAMILY SSF52540 3 153 5.09E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03570 a7834c25e4b52ccdb12897ab0627b700 290 Gene3D G3DSA:3.40.50.300 1 172 3.3E-6 T 14-10-2018 HL41_03570 a7834c25e4b52ccdb12897ab0627b700 290 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 2 288 37.967 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 HL41_03570 a7834c25e4b52ccdb12897ab0627b700 290 PIRSF PIRSF005052 2 290 3.1E-97 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 SUPERFAMILY SSF54211 2 187 4.02E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 SUPERFAMILY SSF55060 186 330 5.92E-31 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 PRINTS PR00960 LmbP protein signature 105 126 6.2E-44 T 14-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 PRINTS PR00960 LmbP protein signature 147 166 6.2E-44 T 14-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 PRINTS PR00960 LmbP protein signature 284 303 6.2E-44 T 14-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 PRINTS PR00960 LmbP protein signature 256 280 6.2E-44 T 14-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 PRINTS PR00960 LmbP protein signature 7 22 6.2E-44 T 14-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 Gene3D G3DSA:3.30.230.120 1 340 2.1E-129 T 14-10-2018 HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 Pfam PF00288 GHMP kinases N terminal domain 101 167 1.1E-12 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 Pfam PF08544 GHMP kinases C terminal 241 322 2.9E-11 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain HL41_06285 e9a7672ad3235e584b346d4e725e16ba 340 PIRSF PIRSF036406 1 340 1.5E-142 T 14-10-2018 IPR014606 D,D-heptose 7-phosphate kinase KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 SUPERFAMILY SSF52021 5 150 3.01E-59 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00097 Anthranilate synthase component II signature 258 269 2.2E-7 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00097 Anthranilate synthase component II signature 231 240 2.2E-7 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00097 Anthranilate synthase component II signature 343 356 2.2E-7 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 228 242 7.7E-38 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 275 292 7.7E-38 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 189 203 7.7E-38 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 274 7.7E-38 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 300 311 7.7E-38 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 4 372 47.618 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 240 1.2E-12 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 258 269 1.2E-12 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 343 356 1.2E-12 T 14-10-2018 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 Gene3D G3DSA:3.40.50.880 153 370 2.1E-64 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 SUPERFAMILY SSF52317 182 370 1.01E-59 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 SMART SM01097 4 134 1.0E-90 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 7 369 2.0E-151 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 6 133 2.2E-54 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 Gene3D G3DSA:3.50.30.20 4 151 4.2E-60 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HL41_05900 fa445976aba969bc2954a5c529dfd81c 377 Pfam PF00117 Glutamine amidotransferase class-I 191 366 1.1E-42 T 14-10-2018 IPR017926 Glutamine amidotransferase HL41_03390 90f80f859c266acf1abf5ac13f901917 476 Gene3D G3DSA:1.10.150.380 300 412 1.2E-36 T 14-10-2018 HL41_03390 90f80f859c266acf1abf5ac13f901917 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 474 8.1E-190 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HL41_03390 90f80f859c266acf1abf5ac13f901917 476 Pfam PF02934 GatB/GatE catalytic domain 5 287 6.4E-116 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 HL41_03390 90f80f859c266acf1abf5ac13f901917 476 SUPERFAMILY SSF55931 4 295 3.73E-124 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 HL41_03390 90f80f859c266acf1abf5ac13f901917 476 Pfam PF02637 GatB domain 327 474 1.6E-50 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 HL41_03390 90f80f859c266acf1abf5ac13f901917 476 SUPERFAMILY SSF89095 296 402 2.09E-31 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 HL41_03390 90f80f859c266acf1abf5ac13f901917 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 475 38.357 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HL41_03390 90f80f859c266acf1abf5ac13f901917 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 143 157 - T 14-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 HL41_03390 90f80f859c266acf1abf5ac13f901917 476 SMART SM00845 327 474 2.1E-71 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 HL41_03390 90f80f859c266acf1abf5ac13f901917 476 Gene3D G3DSA:1.10.10.410 415 476 3.6E-24 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 SUPERFAMILY SSF53784 46 431 1.19E-121 T 14-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 PIRSF PIRSF000534 1 435 3.9E-167 T 14-10-2018 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 Hamap MF_01981 ATP-dependent 6-phosphofructokinase [pfkA]. 5 433 51.676 T 14-10-2018 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 Pfam PF00365 Phosphofructokinase 74 380 6.1E-64 T 14-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 236 252 1.8E-21 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 197 214 1.8E-21 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 293 305 1.8E-21 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 164 180 1.8E-21 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 215 233 1.8E-21 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 77 96 1.8E-21 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HL41_03665 c243409814c6f5af71aa4383e62bd10b 435 Gene3D G3DSA:3.40.50.450 69 262 1.2E-59 T 14-10-2018 HL41_03330 94181d24df053b2045fc15d5e1536afe 366 Gene3D G3DSA:3.10.580.10 172 321 7.1E-37 T 14-10-2018 HL41_03330 94181d24df053b2045fc15d5e1536afe 366 Pfam PF01595 Domain of unknown function DUF21 7 153 4.6E-31 T 14-10-2018 IPR002550 CNNM, transmembrane domain HL41_03330 94181d24df053b2045fc15d5e1536afe 366 SUPERFAMILY SSF54631 188 330 2.27E-21 T 14-10-2018 HL41_00820 6c19944624a30def49de0307d3cdf12d 458 SMART SM00919 228 451 4.5E-110 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 HL41_00820 6c19944624a30def49de0307d3cdf12d 458 SMART SM01274 83 216 8.7E-70 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HL41_00820 6c19944624a30def49de0307d3cdf12d 458 SUPERFAMILY SSF53223 78 226 7.91E-50 T 14-10-2018 HL41_00820 6c19944624a30def49de0307d3cdf12d 458 Pfam PF00390 Malic enzyme, N-terminal domain 85 215 8.3E-26 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HL41_00820 6c19944624a30def49de0307d3cdf12d 458 Pfam PF03949 Malic enzyme, NAD binding domain 230 449 3.5E-24 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 HL41_00820 6c19944624a30def49de0307d3cdf12d 458 Gene3D G3DSA:3.40.50.720 226 454 7.2E-74 T 14-10-2018 HL41_00820 6c19944624a30def49de0307d3cdf12d 458 Gene3D G3DSA:3.40.50.10380 42 225 2.3E-65 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 HL41_00820 6c19944624a30def49de0307d3cdf12d 458 PIRSF PIRSF000106 30 456 8.4E-80 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 HL41_00820 6c19944624a30def49de0307d3cdf12d 458 SUPERFAMILY SSF51735 228 452 7.03E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_03355 551e4a153b70f0ed08a5f2c8e0e31079 139 Gene3D G3DSA:3.40.50.620 1 139 1.6E-31 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_03355 551e4a153b70f0ed08a5f2c8e0e31079 139 PRINTS PR01438 Universal stress protein signature 99 111 4.2E-15 T 14-10-2018 IPR006015 Universal stress protein A HL41_03355 551e4a153b70f0ed08a5f2c8e0e31079 139 PRINTS PR01438 Universal stress protein signature 117 139 4.2E-15 T 14-10-2018 IPR006015 Universal stress protein A HL41_03355 551e4a153b70f0ed08a5f2c8e0e31079 139 PRINTS PR01438 Universal stress protein signature 2 20 4.2E-15 T 14-10-2018 IPR006015 Universal stress protein A HL41_03355 551e4a153b70f0ed08a5f2c8e0e31079 139 Pfam PF00582 Universal stress protein family 1 139 6.2E-29 T 14-10-2018 IPR006016 UspA HL41_03355 551e4a153b70f0ed08a5f2c8e0e31079 139 SUPERFAMILY SSF52402 1 139 4.27E-31 T 14-10-2018 HL41_01830 2497f36de0ed51c13bb60864930e3aca 352 Gene3D G3DSA:3.40.718.10 1 350 4.5E-129 T 14-10-2018 HL41_01830 2497f36de0ed51c13bb60864930e3aca 352 SUPERFAMILY SSF53659 1 344 1.73E-118 T 14-10-2018 HL41_01830 2497f36de0ed51c13bb60864930e3aca 352 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 1 341 1.0E-92 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HL41_01830 2497f36de0ed51c13bb60864930e3aca 352 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 237 256 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 HL41_01830 2497f36de0ed51c13bb60864930e3aca 352 SMART SM01329 1 342 1.1E-172 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 Gene3D G3DSA:2.30.30.790 6 117 1.9E-17 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 Pfam PF01245 Ribosomal protein L19 4 114 5.8E-51 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 PIRSF PIRSF002191 1 121 1.3E-52 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 ProSitePatterns PS01015 Ribosomal protein L19 signature. 87 102 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 SUPERFAMILY SSF50104 2 117 4.01E-48 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 PRINTS PR00061 Ribosomal protein L19 signature 89 114 1.7E-41 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.7E-41 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 PRINTS PR00061 Ribosomal protein L19 signature 35 64 1.7E-41 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 114 3.3E-50 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01440 b15f663af1362ec3656d5191cda3d1b3 121 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 115 32.748 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05025 16f2880ba54407592c6d844f5144c909 166 SUPERFAMILY SSF55040 11 154 2.48E-56 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_05025 16f2880ba54407592c6d844f5144c909 166 Pfam PF01967 MoaC family 15 150 3.6E-52 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_05025 16f2880ba54407592c6d844f5144c909 166 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 158 33.792 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_05025 16f2880ba54407592c6d844f5144c909 166 Gene3D G3DSA:3.30.70.640 1 160 6.8E-62 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_05025 16f2880ba54407592c6d844f5144c909 166 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 1.5E-56 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_01580 56b9755d79915380f54e7f0f1de059de 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 24.008 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01580 56b9755d79915380f54e7f0f1de059de 102 SUPERFAMILY SSF141091 2 101 2.22E-36 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01580 56b9755d79915380f54e7f0f1de059de 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 1.5E-38 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_01580 56b9755d79915380f54e7f0f1de059de 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 14-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_01580 56b9755d79915380f54e7f0f1de059de 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 2.1E-32 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_09060 2633426104b74369fc002d7567da0ac8 423 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 1 420 51.151 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 HL41_09060 2633426104b74369fc002d7567da0ac8 423 Pfam PF04055 Radical SAM superfamily 128 297 1.6E-22 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_09060 2633426104b74369fc002d7567da0ac8 423 Gene3D G3DSA:3.40.50.12160 1 122 3.9E-28 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily HL41_09060 2633426104b74369fc002d7567da0ac8 423 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 416 1.3E-90 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 HL41_09060 2633426104b74369fc002d7567da0ac8 423 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 3 417 4.0E-119 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 HL41_09060 2633426104b74369fc002d7567da0ac8 423 SMART SM00729 122 337 1.4E-39 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_09060 2633426104b74369fc002d7567da0ac8 423 Pfam PF00919 Uncharacterized protein family UPF0004 2 100 7.9E-19 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 HL41_09060 2633426104b74369fc002d7567da0ac8 423 SUPERFAMILY SSF102114 101 345 4.97E-48 T 14-10-2018 HL41_09060 2633426104b74369fc002d7567da0ac8 423 Gene3D G3DSA:2.40.50.140 355 423 3.5E-6 T 14-10-2018 HL41_09060 2633426104b74369fc002d7567da0ac8 423 Gene3D G3DSA:3.80.30.20 123 353 1.5E-71 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HL41_09060 2633426104b74369fc002d7567da0ac8 423 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 126 146 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 HL41_04100 232ea78ddc6af29051f91130bf9e6749 489 ProSitePatterns PS00571 Amidases signature. 154 185 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 HL41_04100 232ea78ddc6af29051f91130bf9e6749 489 PIRSF PIRSF001221 1 449 4.6E-46 T 14-10-2018 HL41_04100 232ea78ddc6af29051f91130bf9e6749 489 PIRSF PIRSF001221 445 480 0.0044 T 14-10-2018 HL41_04100 232ea78ddc6af29051f91130bf9e6749 489 Pfam PF01425 Amidase 27 468 1.1E-165 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HL41_04100 232ea78ddc6af29051f91130bf9e6749 489 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 16 479 1.1E-196 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HL41_04100 232ea78ddc6af29051f91130bf9e6749 489 Gene3D G3DSA:3.90.1300.10 6 485 4.2E-193 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HL41_04100 232ea78ddc6af29051f91130bf9e6749 489 SUPERFAMILY SSF75304 3 478 1.05E-163 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HL41_04100 232ea78ddc6af29051f91130bf9e6749 489 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 14 479 94.623 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 SUPERFAMILY SSF52518 1 180 2.22E-66 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 Gene3D G3DSA:3.40.50.1220 191 360 1.1E-139 T 14-10-2018 HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 SUPERFAMILY SSF52518 365 562 2.36E-69 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 539 2.0E-50 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 Gene3D G3DSA:3.40.50.970 1 182 1.1E-72 T 14-10-2018 HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 326 1.4E-48 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 166 1.2E-59 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 SUPERFAMILY SSF52467 183 360 4.76E-67 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 561 3.1E-266 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HL41_05655 e404cfa11a27ed841ffe75859a906a45 563 Gene3D G3DSA:3.40.50.970 361 539 1.1E-139 T 14-10-2018 HL41_07290 7f216fa65975aa70289536004382e1d9 178 Gene3D G3DSA:3.40.50.10420 1 175 4.4E-31 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily HL41_07290 7f216fa65975aa70289536004382e1d9 178 Pfam PF02589 LUD domain 3 175 1.8E-30 T 14-10-2018 IPR003741 LUD domain HL41_07290 7f216fa65975aa70289536004382e1d9 178 SUPERFAMILY SSF100950 2 176 1.34E-33 T 14-10-2018 IPR037171 NagB/RpiA transferase-like HL41_09030 5847acc62eae8e1eee643f2e7c0d87f6 237 Gene3D G3DSA:3.40.50.2020 127 236 9.9E-18 T 14-10-2018 HL41_09030 5847acc62eae8e1eee643f2e7c0d87f6 237 SUPERFAMILY SSF53271 65 232 6.56E-29 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like HL41_09030 5847acc62eae8e1eee643f2e7c0d87f6 237 Pfam PF00156 Phosphoribosyl transferase domain 193 233 3.6E-9 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HL41_02635 de826bb9c364f47fdde89eafa212b09f 173 PRINTS PR00956 Flagellar motor switch protein FliN signature 92 108 3.8E-28 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HL41_02635 de826bb9c364f47fdde89eafa212b09f 173 PRINTS PR00956 Flagellar motor switch protein FliN signature 109 125 3.8E-28 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HL41_02635 de826bb9c364f47fdde89eafa212b09f 173 PRINTS PR00956 Flagellar motor switch protein FliN signature 125 138 3.8E-28 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HL41_02635 de826bb9c364f47fdde89eafa212b09f 173 PRINTS PR00956 Flagellar motor switch protein FliN signature 138 153 3.8E-28 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HL41_02635 de826bb9c364f47fdde89eafa212b09f 173 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 90 164 1.1E-32 T 14-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 HL41_02635 de826bb9c364f47fdde89eafa212b09f 173 SUPERFAMILY SSF101801 89 171 3.4E-26 T 14-10-2018 IPR036429 SpoA-like superfamily HL41_02635 de826bb9c364f47fdde89eafa212b09f 173 Gene3D G3DSA:2.30.330.10 81 173 1.8E-35 T 14-10-2018 IPR036429 SpoA-like superfamily HL41_02635 de826bb9c364f47fdde89eafa212b09f 173 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 93 162 2.5E-27 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) HL41_05815 2f68df2e0044239ce34cc81205512880 286 Gene3D G3DSA:1.20.810.10 3 186 4.3E-27 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 HL41_05815 2f68df2e0044239ce34cc81205512880 286 Pfam PF00033 Cytochrome b/b6/petB 16 175 7.3E-15 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 HL41_05815 2f68df2e0044239ce34cc81205512880 286 SUPERFAMILY SSF81342 13 178 5.34E-21 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 HL41_08215 8548f575570e95103b58f867794b35ee 410 Gene3D G3DSA:3.90.105.10 28 181 7.6E-103 T 14-10-2018 HL41_08215 8548f575570e95103b58f867794b35ee 410 SUPERFAMILY SSF53218 184 331 5.76E-42 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily HL41_08215 8548f575570e95103b58f867794b35ee 410 Pfam PF03454 MoeA C-terminal region (domain IV) 340 408 5.3E-16 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08215 8548f575570e95103b58f867794b35ee 410 Gene3D G3DSA:3.40.980.10 182 325 7.6E-103 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily HL41_08215 8548f575570e95103b58f867794b35ee 410 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 183 322 4.1E-31 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_08215 8548f575570e95103b58f867794b35ee 410 Pfam PF00994 Probable molybdopterin binding domain 187 325 1.3E-27 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_08215 8548f575570e95103b58f867794b35ee 410 SUPERFAMILY SSF63867 337 409 4.45E-16 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08215 8548f575570e95103b58f867794b35ee 410 Gene3D G3DSA:2.40.340.10 338 410 9.0E-22 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08215 8548f575570e95103b58f867794b35ee 410 Gene3D G3DSA:2.170.190.11 51 148 7.6E-103 T 14-10-2018 HL41_08215 8548f575570e95103b58f867794b35ee 410 SUPERFAMILY SSF63882 6 181 1.7E-49 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08215 8548f575570e95103b58f867794b35ee 410 SMART SM00852 187 326 6.1E-39 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_08215 8548f575570e95103b58f867794b35ee 410 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 174 8.7E-40 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 HL41_08770 16f67eea6ea549622674489edc526f8e 750 Pfam PF00708 Acylphosphatase 5 86 2.1E-22 T 14-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HL41_08770 16f67eea6ea549622674489edc526f8e 750 SUPERFAMILY SSF54975 2 89 9.81E-25 T 14-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HL41_08770 16f67eea6ea549622674489edc526f8e 750 Gene3D G3DSA:3.30.420.350 486 734 5.3E-129 T 14-10-2018 HL41_08770 16f67eea6ea549622674489edc526f8e 750 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 14-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HL41_08770 16f67eea6ea549622674489edc526f8e 750 Pfam PF01300 Telomere recombination 210 383 7.3E-55 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 HL41_08770 16f67eea6ea549622674489edc526f8e 750 PIRSF PIRSF006256 1 750 4.6E-297 T 14-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 HL41_08770 16f67eea6ea549622674489edc526f8e 750 Gene3D G3DSA:3.30.110.120 253 370 5.4E-154 T 14-10-2018 HL41_08770 16f67eea6ea549622674489edc526f8e 750 Gene3D G3DSA:3.30.420.360 382 746 5.3E-129 T 14-10-2018 HL41_08770 16f67eea6ea549622674489edc526f8e 750 Gene3D G3DSA:3.90.870.50 7 361 5.4E-154 T 14-10-2018 HL41_08770 16f67eea6ea549622674489edc526f8e 750 SUPERFAMILY SSF55821 174 390 5.19E-52 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily HL41_08770 16f67eea6ea549622674489edc526f8e 750 Pfam PF07503 HypF finger 107 140 8.4E-16 T 14-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 HL41_08770 16f67eea6ea549622674489edc526f8e 750 Pfam PF07503 HypF finger 157 189 8.4E-16 T 14-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 HL41_08770 16f67eea6ea549622674489edc526f8e 750 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 7 746 4.1E-265 T 14-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 HL41_08770 16f67eea6ea549622674489edc526f8e 750 SUPERFAMILY SSF53067 484 728 1.73E-5 T 14-10-2018 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 Gene3D G3DSA:3.20.20.10 34 275 1.5E-158 T 14-10-2018 IPR029066 PLP-binding barrel HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 Gene3D G3DSA:2.40.37.10 13 409 1.5E-158 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 PRINTS PR01181 Diaminopimelate decarboxylase signature 379 401 3.6E-31 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 3.6E-31 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 3.6E-31 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 3.6E-31 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 226 241 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 SUPERFAMILY SSF50621 253 414 1.7E-59 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 1.7E-23 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 1.7E-23 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 369 382 1.7E-23 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 1.7E-23 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 1.7E-23 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 SUPERFAMILY SSF51419 26 282 3.2E-80 T 14-10-2018 IPR029066 PLP-binding barrel HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 279 4.5E-64 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 411 4.0E-166 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 412 43.645 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HL41_00490 9158ecb6a1217f13ee59df1ba634a57c 418 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 280 369 7.8E-30 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 HL41_06410 e34a25f1e812c1e713d735f41abe80db 537 Gene3D G3DSA:3.40.50.2030 367 535 1.9E-63 T 14-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HL41_06410 e34a25f1e812c1e713d735f41abe80db 537 Gene3D G3DSA:1.20.1270.20 138 220 1.9E-27 T 14-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HL41_06410 e34a25f1e812c1e713d735f41abe80db 537 Gene3D G3DSA:1.20.1270.20 1 127 7.0E-36 T 14-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HL41_06410 e34a25f1e812c1e713d735f41abe80db 537 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 534 1.1E-227 T 14-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HL41_06410 e34a25f1e812c1e713d735f41abe80db 537 Pfam PF03063 Prismane/CO dehydrogenase family 1 531 1.8E-160 T 14-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 HL41_06410 e34a25f1e812c1e713d735f41abe80db 537 Gene3D G3DSA:3.40.50.2030 222 366 8.1E-68 T 14-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HL41_06410 e34a25f1e812c1e713d735f41abe80db 537 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 536 20.533 T 14-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HL41_06410 e34a25f1e812c1e713d735f41abe80db 537 PIRSF PIRSF000076 1 537 2.6E-223 T 14-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HL41_06410 e34a25f1e812c1e713d735f41abe80db 537 SUPERFAMILY SSF56821 1 535 5.36E-190 T 14-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 HL41_08095 816ea5dc635e3373b73f78c69e1aabf9 266 SUPERFAMILY SSF88713 55 224 2.4E-30 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HL41_08095 816ea5dc635e3373b73f78c69e1aabf9 266 Pfam PF01522 Polysaccharide deacetylase 90 218 4.9E-21 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HL41_08095 816ea5dc635e3373b73f78c69e1aabf9 266 Gene3D G3DSA:3.20.20.370 35 261 5.1E-50 T 14-10-2018 HL41_06070 02a091e57c65964d41ec7457d87b8ef2 758 Pfam PF07559 Flagellar basal body protein FlaE 427 638 2.1E-19 T 14-10-2018 IPR011491 Flagellar hook protein FlgE HL41_06070 02a091e57c65964d41ec7457d87b8ef2 758 SUPERFAMILY SSF117143 84 352 8.63E-27 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like HL41_06070 02a091e57c65964d41ec7457d87b8ef2 758 SUPERFAMILY SSF117143 366 718 3.53E-34 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like HL41_06070 02a091e57c65964d41ec7457d87b8ef2 758 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 406 738 1.5E-42 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G HL41_06070 02a091e57c65964d41ec7457d87b8ef2 758 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 6 158 3.2E-44 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G HL41_06070 02a091e57c65964d41ec7457d87b8ef2 758 Gene3D G3DSA:2.60.98.20 398 511 2.1E-6 T 14-10-2018 IPR037058 Flagellar hook protein FlgE superfamily HL41_06070 02a091e57c65964d41ec7457d87b8ef2 758 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 679 756 3.0E-19 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HL41_04355 f8183f0c2309f369af2c8cd3de6ca2dc 703 Pfam PF06202 Amylo-alpha-1,6-glucosidase 268 632 1.3E-17 T 14-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 HL41_04355 f8183f0c2309f369af2c8cd3de6ca2dc 703 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 12 203 4.7E-45 T 14-10-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal HL41_04355 f8183f0c2309f369af2c8cd3de6ca2dc 703 SUPERFAMILY SSF48208 220 685 7.49E-90 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 HL41_04355 f8183f0c2309f369af2c8cd3de6ca2dc 703 Gene3D G3DSA:1.50.10.10 245 639 3.3E-57 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 HL41_02940 cd0161b2404136197e351014f6ffd2fa 190 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 5 184 1.4E-63 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like HL41_02940 cd0161b2404136197e351014f6ffd2fa 190 SUPERFAMILY SSF52507 3 186 1.57E-55 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 HL41_02940 cd0161b2404136197e351014f6ffd2fa 190 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 3 186 32.923 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like HL41_02940 cd0161b2404136197e351014f6ffd2fa 190 Pfam PF02441 Flavoprotein 3 187 6.3E-28 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HL41_02940 cd0161b2404136197e351014f6ffd2fa 190 Gene3D G3DSA:3.40.50.1950 1 189 1.3E-71 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 HL41_03480 5fcfa8b9f84109246f6bc1782972627f 177 SUPERFAMILY SSF56784 10 173 2.13E-40 T 14-10-2018 IPR036412 HAD-like superfamily HL41_03480 5fcfa8b9f84109246f6bc1782972627f 177 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 15 127 1.0E-12 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 HL41_03480 5fcfa8b9f84109246f6bc1782972627f 177 Pfam PF08282 haloacid dehalogenase-like hydrolase 65 146 6.0E-7 T 14-10-2018 HL41_03480 5fcfa8b9f84109246f6bc1782972627f 177 Gene3D G3DSA:3.40.50.1000 1 177 3.7E-56 T 14-10-2018 IPR023214 HAD superfamily HL41_03480 5fcfa8b9f84109246f6bc1782972627f 177 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 14 166 2.7E-55 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 HL41_03480 5fcfa8b9f84109246f6bc1782972627f 177 PIRSF PIRSF006118 1 176 1.7E-68 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 HL41_02390 8fb121128017fab1b00363de7571f620 599 Gene3D G3DSA:1.10.599.10 239 599 1.8E-148 T 14-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 HL41_02390 8fb121128017fab1b00363de7571f620 599 SUPERFAMILY SSF48310 210 599 6.28E-147 T 14-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HL41_02390 8fb121128017fab1b00363de7571f620 599 Gene3D G3DSA:3.60.9.10 1 210 6.8E-96 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily HL41_02390 8fb121128017fab1b00363de7571f620 599 Gene3D G3DSA:1.10.569.10 241 427 1.8E-148 T 14-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 HL41_02390 8fb121128017fab1b00363de7571f620 599 SMART SM00790 4 206 4.7E-133 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HL41_02390 8fb121128017fab1b00363de7571f620 599 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 223 599 4.4E-150 T 14-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HL41_02390 8fb121128017fab1b00363de7571f620 599 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 204 4.4E-87 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HL41_02390 8fb121128017fab1b00363de7571f620 599 SUPERFAMILY SSF56228 1 210 8.89E-82 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily HL41_09085 c49a7500d66c182b6152487b192201c9 331 SUPERFAMILY SSF53807 30 324 3.06E-62 T 14-10-2018 HL41_09085 c49a7500d66c182b6152487b192201c9 331 Gene3D G3DSA:3.40.50.1980 25 161 3.3E-42 T 14-10-2018 HL41_09085 c49a7500d66c182b6152487b192201c9 331 Pfam PF01497 Periplasmic binding protein 53 276 1.3E-28 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain HL41_09085 c49a7500d66c182b6152487b192201c9 331 Gene3D G3DSA:3.40.50.1980 164 328 5.3E-45 T 14-10-2018 HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 Pfam PF00155 Aminotransferase class I and II 32 391 6.4E-70 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 Gene3D G3DSA:3.90.1150.10 26 391 5.0E-134 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 SUPERFAMILY SSF53383 1 395 1.73E-117 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 Gene3D G3DSA:3.40.640.10 63 285 5.0E-134 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 115 136 4.1E-11 T 14-10-2018 HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 198 221 4.1E-11 T 14-10-2018 HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 93 113 4.1E-11 T 14-10-2018 HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 162 186 4.1E-11 T 14-10-2018 HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 229 253 4.1E-11 T 14-10-2018 HL41_04290 6f1d9b879aec02d5fb93606d0e814c2f 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 HL41_01295 573dec275573501031e9742f3cb163d2 427 SUPERFAMILY SSF56059 103 319 1.13E-60 T 14-10-2018 HL41_01295 573dec275573501031e9742f3cb163d2 427 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 288 295 - T 14-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_01295 573dec275573501031e9742f3cb163d2 427 SMART SM01209 102 294 2.1E-127 T 14-10-2018 HL41_01295 573dec275573501031e9742f3cb163d2 427 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 294 8.2E-79 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_01295 573dec275573501031e9742f3cb163d2 427 SMART SM01210 328 422 7.3E-54 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_01295 573dec275573501031e9742f3cb163d2 427 Gene3D G3DSA:3.30.1490.20 120 189 6.2E-30 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HL41_01295 573dec275573501031e9742f3cb163d2 427 Gene3D G3DSA:3.30.470.20 190 327 1.3E-54 T 14-10-2018 HL41_01295 573dec275573501031e9742f3cb163d2 427 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 422 7.6E-168 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_01295 573dec275573501031e9742f3cb163d2 427 Gene3D G3DSA:3.90.600.10 328 427 5.9E-40 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_01295 573dec275573501031e9742f3cb163d2 427 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 422 41.261 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_01295 573dec275573501031e9742f3cb163d2 427 SUPERFAMILY SSF52440 1 102 9.93E-31 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily HL41_01295 573dec275573501031e9742f3cb163d2 427 Gene3D G3DSA:3.40.50.20 2 94 5.4E-32 T 14-10-2018 HL41_01295 573dec275573501031e9742f3cb163d2 427 SUPERFAMILY SSF51246 326 422 5.07E-32 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HL41_01295 573dec275573501031e9742f3cb163d2 427 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 420 5.2E-32 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_01295 573dec275573501031e9742f3cb163d2 427 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 6.6E-32 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HL41_02725 f02449da27b043af127c5fe6fd7d0574 292 Gene3D G3DSA:3.30.70.20 253 289 3.8E-5 T 14-10-2018 HL41_02725 f02449da27b043af127c5fe6fd7d0574 292 Pfam PF12838 4Fe-4S dicluster domain 206 248 2.8E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_02725 f02449da27b043af127c5fe6fd7d0574 292 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 260 271 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_02725 f02449da27b043af127c5fe6fd7d0574 292 SUPERFAMILY SSF54862 84 277 5.47E-17 T 14-10-2018 HL41_02725 f02449da27b043af127c5fe6fd7d0574 292 Pfam PF12801 4Fe-4S binding domain 153 164 14.0 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_02725 f02449da27b043af127c5fe6fd7d0574 292 Pfam PF12801 4Fe-4S binding domain 51 62 25.0 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_02725 f02449da27b043af127c5fe6fd7d0574 292 Pfam PF12801 4Fe-4S binding domain 75 118 3.1E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_02725 f02449da27b043af127c5fe6fd7d0574 292 Gene3D G3DSA:3.30.70.20 206 252 9.9E-9 T 14-10-2018 HL41_02725 f02449da27b043af127c5fe6fd7d0574 292 Pfam PF00037 4Fe-4S binding domain 255 276 2.8E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_00125 a2fe30e5d85e0269bffda9ba844cc86e 185 SUPERFAMILY SSF117457 24 183 9.15E-46 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 HL41_00125 a2fe30e5d85e0269bffda9ba844cc86e 185 Pfam PF05683 Fumarase C-terminus 25 184 1.5E-44 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HL41_00125 a2fe30e5d85e0269bffda9ba844cc86e 185 Gene3D G3DSA:3.20.130.10 3 184 2.5E-52 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 HL41_01200 cf9bd9b3e7c22f7aa8eb727274653f9d 106 Pfam PF04358 DsrC like protein 6 106 4.5E-34 T 14-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE HL41_01200 cf9bd9b3e7c22f7aa8eb727274653f9d 106 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 5 106 7.0E-33 T 14-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE HL41_01200 cf9bd9b3e7c22f7aa8eb727274653f9d 106 PIRSF PIRSF006223 4 106 3.1E-32 T 14-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE HL41_01200 cf9bd9b3e7c22f7aa8eb727274653f9d 106 Gene3D G3DSA:3.30.1420.10 1 42 3.3E-17 T 14-10-2018 HL41_01200 cf9bd9b3e7c22f7aa8eb727274653f9d 106 SUPERFAMILY SSF69721 1 106 4.84E-37 T 14-10-2018 IPR025526 DsrC-like domain superfamily HL41_01200 cf9bd9b3e7c22f7aa8eb727274653f9d 106 Gene3D G3DSA:1.10.10.370 43 106 5.1E-29 T 14-10-2018 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 SUPERFAMILY SSF54919 1 138 6.94E-60 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 Pfam PF00334 Nucleoside diphosphate kinase 2 135 6.3E-58 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 14-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 4.2E-41 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 4.2E-41 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 4.2E-41 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 4.2E-41 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 4.2E-41 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 Gene3D G3DSA:3.30.70.141 1 140 4.9E-61 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 35.722 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_03545 bb54afd5d3a4a66fbc8ec85da4318f08 140 SMART SM00562 1 138 1.4E-89 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HL41_00685 1c4a21c37ac6f773d8c0315f90bb663e 270 SMART SM01211 3 265 2.4E-113 T 14-10-2018 HL41_00685 1c4a21c37ac6f773d8c0315f90bb663e 270 Gene3D G3DSA:3.40.50.880 1 266 3.5E-84 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_00685 1c4a21c37ac6f773d8c0315f90bb663e 270 SUPERFAMILY SSF52317 1 265 5.99E-76 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_00685 1c4a21c37ac6f773d8c0315f90bb663e 270 PIRSF PIRSF001586 2 268 5.0E-75 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HL41_00685 1c4a21c37ac6f773d8c0315f90bb663e 270 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 3 265 5.9E-87 T 14-10-2018 HL41_08130 9239bfe0b919bbc86e91144ab23e9ec0 154 SUPERFAMILY SSF54534 3 144 9.43E-37 T 14-10-2018 HL41_08130 9239bfe0b919bbc86e91144ab23e9ec0 154 Gene3D G3DSA:3.10.50.40 2 153 7.6E-41 T 14-10-2018 HL41_08130 9239bfe0b919bbc86e91144ab23e9ec0 154 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 139 3.4E-20 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain HL41_04545 2ea59d8c25502ba2e352441025ed215e 316 SUPERFAMILY SSF52540 31 152 9.39E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04545 2ea59d8c25502ba2e352441025ed215e 316 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 4 310 25.695 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 HL41_04545 2ea59d8c25502ba2e352441025ed215e 316 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 9 299 2.7E-60 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 HL41_04545 2ea59d8c25502ba2e352441025ed215e 316 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 8 299 3.1E-69 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 HL41_05675 8112fc1e0a6fe6412714fc69452f5c56 73 Pfam PF02416 mttA/Hcf106 family 5 58 1.5E-16 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 HL41_05675 8112fc1e0a6fe6412714fc69452f5c56 73 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 2.8E-16 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HL41_05675 8112fc1e0a6fe6412714fc69452f5c56 73 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 72 18.177 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HL41_04530 bd754e67c4928386cb13eaf7c92130ec 219 SUPERFAMILY SSF52540 5 217 2.08E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04530 bd754e67c4928386cb13eaf7c92130ec 219 Pfam PF00005 ABC transporter 20 165 1.6E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_04530 bd754e67c4928386cb13eaf7c92130ec 219 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_04530 bd754e67c4928386cb13eaf7c92130ec 219 Gene3D G3DSA:3.40.50.300 2 219 4.4E-56 T 14-10-2018 HL41_04530 bd754e67c4928386cb13eaf7c92130ec 219 SMART SM00382 29 214 3.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_07885 e6e6ebe232e6015b0c03a275612e5c02 350 Gene3D G3DSA:3.40.50.2000 173 320 4.4E-61 T 14-10-2018 HL41_07885 e6e6ebe232e6015b0c03a275612e5c02 350 SUPERFAMILY SSF53756 3 347 4.93E-50 T 14-10-2018 HL41_07885 e6e6ebe232e6015b0c03a275612e5c02 350 Gene3D G3DSA:3.40.50.2000 15 172 4.4E-61 T 14-10-2018 HL41_07885 e6e6ebe232e6015b0c03a275612e5c02 350 Pfam PF00534 Glycosyl transferases group 1 188 330 3.9E-23 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 HL41_03750 e52cc5cf27cbe3379ef7fd4e30ffca60 421 Gene3D G3DSA:3.40.50.11890 70 196 4.7E-35 T 14-10-2018 HL41_03750 e52cc5cf27cbe3379ef7fd4e30ffca60 421 Gene3D G3DSA:3.40.50.11900 278 421 7.0E-40 T 14-10-2018 HL41_03750 e52cc5cf27cbe3379ef7fd4e30ffca60 421 Gene3D G3DSA:1.20.1270.370 61 262 4.7E-35 T 14-10-2018 HL41_03750 e52cc5cf27cbe3379ef7fd4e30ffca60 421 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 77 421 1.3E-76 T 14-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.8E-52 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.2E-37 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.2E-37 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.2E-37 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.2E-37 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.79 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 Gene3D G3DSA:3.90.1170.10 1 137 2.2E-60 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 SUPERFAMILY SSF54686 2 136 2.09E-58 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05410 a8837ad56c36f571a5057557dad95d0b 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 9.9E-61 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04430 9b639a09a1bb6398b5b64f9e9d51eac0 577 Gene3D G3DSA:1.20.1560.10 3 325 6.8E-68 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HL41_04430 9b639a09a1bb6398b5b64f9e9d51eac0 577 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_04430 9b639a09a1bb6398b5b64f9e9d51eac0 577 Gene3D G3DSA:3.40.50.300 326 575 4.4E-82 T 14-10-2018 HL41_04430 9b639a09a1bb6398b5b64f9e9d51eac0 577 Pfam PF00005 ABC transporter 354 503 2.3E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_04430 9b639a09a1bb6398b5b64f9e9d51eac0 577 Pfam PF00664 ABC transporter transmembrane region 24 293 2.7E-40 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 HL41_04430 9b639a09a1bb6398b5b64f9e9d51eac0 577 SMART SM00382 363 549 1.6E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_04430 9b639a09a1bb6398b5b64f9e9d51eac0 577 SUPERFAMILY SSF90123 10 323 7.72E-64 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 HL41_04430 9b639a09a1bb6398b5b64f9e9d51eac0 577 SUPERFAMILY SSF52540 329 572 1.63E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07330 a8e765b6c4fe937433ce8c1bb987b0b9 97 Pfam PF14697 4Fe-4S dicluster domain 39 92 7.4E-9 T 14-10-2018 HL41_07330 a8e765b6c4fe937433ce8c1bb987b0b9 97 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 20 96 1.3E-29 T 14-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 HL41_07330 a8e765b6c4fe937433ce8c1bb987b0b9 97 Gene3D G3DSA:3.30.70.20 18 97 3.4E-13 T 14-10-2018 HL41_07330 a8e765b6c4fe937433ce8c1bb987b0b9 97 SUPERFAMILY SSF54862 11 95 5.02E-18 T 14-10-2018 HL41_07330 a8e765b6c4fe937433ce8c1bb987b0b9 97 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_02870 a5cf1f954b9fe6dcf8620a32b698f1ee 245 Pfam PF00005 ABC transporter 17 158 4.4E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_02870 a5cf1f954b9fe6dcf8620a32b698f1ee 245 Gene3D G3DSA:3.40.50.300 1 234 1.9E-49 T 14-10-2018 HL41_02870 a5cf1f954b9fe6dcf8620a32b698f1ee 245 SUPERFAMILY SSF52540 2 230 9.18E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02870 a5cf1f954b9fe6dcf8620a32b698f1ee 245 SMART SM00382 26 218 7.2E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_06815 cfb13b91e80ca4ae78ed91f5e7fcf947 281 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 211 231 1.3E-5 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 HL41_06815 cfb13b91e80ca4ae78ed91f5e7fcf947 281 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 190 210 1.3E-5 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 HL41_06815 cfb13b91e80ca4ae78ed91f5e7fcf947 281 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 47 278 1.7E-70 T 14-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 HL41_06815 cfb13b91e80ca4ae78ed91f5e7fcf947 281 Pfam PF01578 Cytochrome C assembly protein 74 275 1.2E-51 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 HL41_05625 e0f73173d36fe8662edfb85d489b1edf 129 Pfam PF00380 Ribosomal protein S9/S16 8 129 1.6E-47 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 HL41_05625 e0f73173d36fe8662edfb85d489b1edf 129 SUPERFAMILY SSF54211 3 129 1.71E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_05625 e0f73173d36fe8662edfb85d489b1edf 129 Gene3D G3DSA:3.30.230.10 1 129 2.2E-51 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_05625 e0f73173d36fe8662edfb85d489b1edf 129 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 129 29.472 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid HL41_05625 e0f73173d36fe8662edfb85d489b1edf 129 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 HL41_05630 ba86a62b54c0d1076ab18f8ba37055c1 148 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 12 147 3.8E-61 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05630 ba86a62b54c0d1076ab18f8ba37055c1 148 Gene3D G3DSA:3.90.1180.10 8 148 2.1E-61 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05630 ba86a62b54c0d1076ab18f8ba37055c1 148 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 21 147 27.562 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HL41_05630 ba86a62b54c0d1076ab18f8ba37055c1 148 ProSitePatterns PS00783 Ribosomal protein L13 signature. 111 133 - T 14-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 HL41_05630 ba86a62b54c0d1076ab18f8ba37055c1 148 Pfam PF00572 Ribosomal protein L13 20 144 9.1E-55 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HL41_05630 ba86a62b54c0d1076ab18f8ba37055c1 148 SUPERFAMILY SSF52161 9 145 7.19E-55 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05630 ba86a62b54c0d1076ab18f8ba37055c1 148 PIRSF PIRSF002181 6 147 4.7E-52 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HL41_01895 218ad7d2cd316e9e0c5cc9e0bcca074b 363 SUPERFAMILY SSF52540 3 336 4.59E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01895 218ad7d2cd316e9e0c5cc9e0bcca074b 363 SMART SM00382 123 248 1.6E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_01895 218ad7d2cd316e9e0c5cc9e0bcca074b 363 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 343 2.6E-142 T 14-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 HL41_01895 218ad7d2cd316e9e0c5cc9e0bcca074b 363 Pfam PF00437 Type II/IV secretion system protein 120 266 2.7E-39 T 14-10-2018 IPR001482 Type II/IV secretion system protein HL41_01895 218ad7d2cd316e9e0c5cc9e0bcca074b 363 Gene3D G3DSA:3.30.450.90 1 100 5.4E-34 T 14-10-2018 HL41_01895 218ad7d2cd316e9e0c5cc9e0bcca074b 363 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 194 208 - T 14-10-2018 IPR001482 Type II/IV secretion system protein HL41_01895 218ad7d2cd316e9e0c5cc9e0bcca074b 363 Gene3D G3DSA:3.40.50.300 102 356 3.6E-99 T 14-10-2018 HL41_04265 ac50a743ce100f475709768fff48f46d 861 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 9.9E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HL41_04265 ac50a743ce100f475709768fff48f46d 861 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 9.9E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HL41_04265 ac50a743ce100f475709768fff48f46d 861 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 9.9E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HL41_04265 ac50a743ce100f475709768fff48f46d 861 PRINTS PR00985 Leucyl-tRNA synthetase signature 562 572 9.9E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HL41_04265 ac50a743ce100f475709768fff48f46d 861 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 9.9E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HL41_04265 ac50a743ce100f475709768fff48f46d 861 PRINTS PR00985 Leucyl-tRNA synthetase signature 491 509 9.9E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HL41_04265 ac50a743ce100f475709768fff48f46d 861 PRINTS PR00985 Leucyl-tRNA synthetase signature 529 551 9.9E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HL41_04265 ac50a743ce100f475709768fff48f46d 861 SUPERFAMILY SSF47323 657 861 2.24E-35 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 613 654 5.9E-8 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 171 2.8E-30 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 420 577 5.9E-9 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Pfam PF08264 Anticodon-binding domain of tRNA 701 823 2.9E-23 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 HL41_04265 ac50a743ce100f475709768fff48f46d 861 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 52 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Gene3D G3DSA:3.90.740.10 227 417 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HL41_04265 ac50a743ce100f475709768fff48f46d 861 SUPERFAMILY SSF50677 226 418 1.15E-53 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Gene3D G3DSA:3.10.20.590 801 861 3.3E-23 T 14-10-2018 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 406 1.4E-68 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Gene3D G3DSA:3.10.330.110 572 623 0.0 T 14-10-2018 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Gene3D G3DSA:3.40.50.620 32 571 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_04265 ac50a743ce100f475709768fff48f46d 861 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 861 23.253 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HL41_04265 ac50a743ce100f475709768fff48f46d 861 SUPERFAMILY SSF52374 3 663 6.61E-155 T 14-10-2018 HL41_04265 ac50a743ce100f475709768fff48f46d 861 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 861 0.0 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HL41_04265 ac50a743ce100f475709768fff48f46d 861 Gene3D G3DSA:1.10.730.10 8 792 0.0 T 14-10-2018 HL41_08600 02bdc0ea9d11b636cfa7f648d16a80ad 98 Pfam PF02915 Rubrerythrin 21 89 8.1E-7 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HL41_08600 02bdc0ea9d11b636cfa7f648d16a80ad 98 SUPERFAMILY SSF47240 12 78 5.08E-17 T 14-10-2018 IPR009078 Ferritin-like superfamily HL41_08600 02bdc0ea9d11b636cfa7f648d16a80ad 98 Gene3D G3DSA:1.20.1260.10 17 98 7.4E-9 T 14-10-2018 IPR012347 Ferritin-like HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 Gene3D G3DSA:2.40.50.140 1 109 1.2E-33 T 14-10-2018 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 Gene3D G3DSA:3.30.1360.30 279 427 5.8E-193 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 4 589 2.5E-230 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 482 498 1.9E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 526 540 1.9E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 209 1.9E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 214 227 1.9E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 Pfam PF01336 OB-fold nucleic acid binding domain 21 105 2.4E-18 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 SUPERFAMILY SSF50249 3 113 1.1E-32 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 Gene3D G3DSA:3.30.930.10 123 589 5.8E-193 T 14-10-2018 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 Pfam PF00152 tRNA synthetases class II (D, K and N) 125 566 2.1E-106 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 SUPERFAMILY SSF55261 296 427 1.8E-33 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 592 33.949 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 SUPERFAMILY SSF55681 121 588 2.87E-105 T 14-10-2018 HL41_01230 5cc6d4e497e92487735e62f9b0caf4a0 600 Pfam PF02938 GAD domain 315 410 2.3E-17 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 HL41_01935 2f4c10d580b9488652ea4a6c2dbef2e0 394 Pfam PF04055 Radical SAM superfamily 45 199 4.3E-27 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_01935 2f4c10d580b9488652ea4a6c2dbef2e0 394 TIGRFAM TIGR04546 rSAM_ahbC_deAc: 12,18-didecarboxysiroheme deacetylase 2 391 2.0E-217 T 14-10-2018 IPR030894 12,18-Didecarboxysiroheme deacetylase HL41_01935 2f4c10d580b9488652ea4a6c2dbef2e0 394 Gene3D G3DSA:3.20.20.70 38 352 5.6E-54 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_01935 2f4c10d580b9488652ea4a6c2dbef2e0 394 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 301 384 1.7E-8 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain HL41_01935 2f4c10d580b9488652ea4a6c2dbef2e0 394 SMART SM00729 40 246 2.3E-7 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_01935 2f4c10d580b9488652ea4a6c2dbef2e0 394 SUPERFAMILY SSF102114 41 364 2.75E-75 T 14-10-2018 HL41_01935 2f4c10d580b9488652ea4a6c2dbef2e0 394 Pfam PF13186 Iron-sulfur cluster-binding domain 301 356 3.7E-5 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain HL41_01935 2f4c10d580b9488652ea4a6c2dbef2e0 394 PIRSF PIRSF037420 21 394 7.6E-144 T 14-10-2018 IPR017200 Coenzyme PQQ synthesis protein E HL41_01935 2f4c10d580b9488652ea4a6c2dbef2e0 394 Pfam PF13353 4Fe-4S single cluster domain 42 149 1.6E-9 T 14-10-2018 HL41_01015 8086a24d6915a9825704df117358596d 400 TIGRFAM TIGR01265 tyr_nico_aTase: tyrosine/nicotianamine family aminotransferase 16 398 1.1E-98 T 14-10-2018 IPR005958 Tyrosine/nicotianamine aminotransferase GO:0006520|GO:0008483|GO:0030170 Reactome: R-HSA-71182 HL41_01015 8086a24d6915a9825704df117358596d 400 SUPERFAMILY SSF53383 17 398 9.71E-99 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_01015 8086a24d6915a9825704df117358596d 400 Gene3D G3DSA:3.40.640.10 55 295 8.7E-124 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_01015 8086a24d6915a9825704df117358596d 400 PIRSF PIRSF000517 9 400 3.8E-100 T 14-10-2018 IPR005958 Tyrosine/nicotianamine aminotransferase GO:0006520|GO:0008483|GO:0030170 Reactome: R-HSA-71182 HL41_01015 8086a24d6915a9825704df117358596d 400 Gene3D G3DSA:3.90.1150.10 24 395 8.7E-124 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_01015 8086a24d6915a9825704df117358596d 400 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 97 117 3.2E-11 T 14-10-2018 HL41_01015 8086a24d6915a9825704df117358596d 400 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 119 140 3.2E-11 T 14-10-2018 HL41_01015 8086a24d6915a9825704df117358596d 400 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 166 190 3.2E-11 T 14-10-2018 HL41_01015 8086a24d6915a9825704df117358596d 400 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 232 256 3.2E-11 T 14-10-2018 HL41_01015 8086a24d6915a9825704df117358596d 400 Pfam PF00155 Aminotransferase class I and II 36 392 1.4E-60 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HL41_02345 357fe351a0a91f67e54878eca870c9ad 253 SUPERFAMILY SSF110997 177 251 1.44E-10 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 HL41_02345 357fe351a0a91f67e54878eca870c9ad 253 Pfam PF03330 Lytic transglycolase 68 154 7.2E-24 T 14-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain HL41_02345 357fe351a0a91f67e54878eca870c9ad 253 Gene3D G3DSA:2.40.40.10 65 157 6.2E-36 T 14-10-2018 IPR036908 RlpA-like domain superfamily HL41_02345 357fe351a0a91f67e54878eca870c9ad 253 Gene3D G3DSA:3.30.70.1070 178 252 3.3E-9 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 HL41_02345 357fe351a0a91f67e54878eca870c9ad 253 Pfam PF05036 Sporulation related domain 177 249 1.3E-10 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 HL41_02345 357fe351a0a91f67e54878eca870c9ad 253 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 68 161 6.0E-43 T 14-10-2018 IPR012997 Rare lipoprotein A HL41_02345 357fe351a0a91f67e54878eca870c9ad 253 SUPERFAMILY SSF50685 61 154 7.67E-14 T 14-10-2018 IPR036908 RlpA-like domain superfamily HL41_02345 357fe351a0a91f67e54878eca870c9ad 253 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 37 157 23.063 T 14-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 Gene3D G3DSA:3.40.50.620 295 614 1.2E-89 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 296 3.6E-110 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 310 771 26.919 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 SUPERFAMILY SSF47323 643 768 4.84E-20 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 534 555 1.5E-8 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 333 344 1.5E-8 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 369 378 1.5E-8 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 503 521 1.5E-8 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 Gene3D G3DSA:3.40.50.1100 44 144 6.3E-107 T 14-10-2018 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 Gene3D G3DSA:1.20.120.1910 615 770 3.5E-23 T 14-10-2018 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 311 768 2.3E-106 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 285 2.8E-68 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 Gene3D G3DSA:3.40.50.1100 5 292 6.3E-107 T 14-10-2018 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 SUPERFAMILY SSF52374 312 622 3.75E-61 T 14-10-2018 HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 SUPERFAMILY SSF53686 2 298 1.57E-90 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HL41_07435 ff7a28ce8973cc1a8cdc82829eb6ef8f 773 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 325 623 4.4E-77 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 HL41_01025 97e582d7b1e7e198522b22db7bbb7558 502 Gene3D G3DSA:1.25.40.10 424 494 2.6E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_01025 97e582d7b1e7e198522b22db7bbb7558 502 SMART SM00028 320 353 470.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_01025 97e582d7b1e7e198522b22db7bbb7558 502 SMART SM00028 286 319 46.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_01025 97e582d7b1e7e198522b22db7bbb7558 502 SMART SM00028 420 453 22.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_01025 97e582d7b1e7e198522b22db7bbb7558 502 SMART SM00028 355 388 6.2E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_01025 97e582d7b1e7e198522b22db7bbb7558 502 Gene3D G3DSA:1.25.40.10 267 423 2.0E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_01025 97e582d7b1e7e198522b22db7bbb7558 502 Pfam PF07719 Tetratricopeptide repeat 356 388 1.7E-5 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 HL41_01025 97e582d7b1e7e198522b22db7bbb7558 502 Pfam PF13181 Tetratricopeptide repeat 288 312 0.2 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_01025 97e582d7b1e7e198522b22db7bbb7558 502 SUPERFAMILY SSF48452 288 475 1.29E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_07420 b9047344036315528ac2ced5aaaf86cf 170 Gene3D G3DSA:3.40.50.300 1 169 4.4E-61 T 14-10-2018 HL41_07420 b9047344036315528ac2ced5aaaf86cf 170 SUPERFAMILY SSF52540 2 169 6.03E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07420 b9047344036315528ac2ced5aaaf86cf 170 PIRSF PIRSF015617 1 170 6.2E-57 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 HL41_07420 b9047344036315528ac2ced5aaaf86cf 170 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 3 169 1.1E-61 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 HL41_05975 adc7ecea3b56c1efda18c9a09d22558a 68 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 3 66 16.032 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HL41_05975 adc7ecea3b56c1efda18c9a09d22558a 68 SUPERFAMILY SSF143034 4 66 2.09E-19 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05975 adc7ecea3b56c1efda18c9a09d22558a 68 PRINTS PR00064 Ribosomal protein L35 signature 38 56 4.5E-17 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HL41_05975 adc7ecea3b56c1efda18c9a09d22558a 68 PRINTS PR00064 Ribosomal protein L35 signature 5 22 4.5E-17 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HL41_05975 adc7ecea3b56c1efda18c9a09d22558a 68 PRINTS PR00064 Ribosomal protein L35 signature 23 37 4.5E-17 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HL41_05975 adc7ecea3b56c1efda18c9a09d22558a 68 ProSitePatterns PS00936 Ribosomal protein L35 signature. 7 33 - T 14-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05975 adc7ecea3b56c1efda18c9a09d22558a 68 Pfam PF01632 Ribosomal protein L35 5 55 1.6E-19 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05975 adc7ecea3b56c1efda18c9a09d22558a 68 Gene3D G3DSA:2.40.50.530 5 67 8.2E-19 T 14-10-2018 HL41_05975 adc7ecea3b56c1efda18c9a09d22558a 68 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 5 66 3.4E-23 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HL41_04540 88a05ae04d49a53c4f40a478b5d865bc 271 Gene3D G3DSA:3.40.190.10 104 218 2.1E-96 T 14-10-2018 HL41_04540 88a05ae04d49a53c4f40a478b5d865bc 271 SUPERFAMILY SSF53850 27 256 1.01E-30 T 14-10-2018 HL41_04540 88a05ae04d49a53c4f40a478b5d865bc 271 Pfam PF12849 PBP superfamily domain 28 249 1.1E-24 T 14-10-2018 IPR024370 PBP domain HL41_04540 88a05ae04d49a53c4f40a478b5d865bc 271 Gene3D G3DSA:3.40.190.10 29 255 2.1E-96 T 14-10-2018 HL41_01900 6e58152123dbe2b8b84de5e765708d87 387 Gene3D G3DSA:3.40.50.300 114 371 2.9E-84 T 14-10-2018 HL41_01900 6e58152123dbe2b8b84de5e765708d87 387 SMART SM00382 135 260 6.6E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_01900 6e58152123dbe2b8b84de5e765708d87 387 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 17 355 4.3E-108 T 14-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 HL41_01900 6e58152123dbe2b8b84de5e765708d87 387 SUPERFAMILY SSF52540 71 346 8.49E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01900 6e58152123dbe2b8b84de5e765708d87 387 Gene3D G3DSA:3.30.450.90 3 112 2.6E-13 T 14-10-2018 HL41_01900 6e58152123dbe2b8b84de5e765708d87 387 Pfam PF00437 Type II/IV secretion system protein 89 257 3.4E-36 T 14-10-2018 IPR001482 Type II/IV secretion system protein HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Gene3D G3DSA:2.40.160.50 551 877 4.2E-96 T 14-10-2018 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 PIRSF PIRSF006076 107 877 9.7E-215 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 PIRSF PIRSF006076 31 101 97.0 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Gene3D G3DSA:3.10.20.310 211 288 2.2E-13 T 14-10-2018 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Pfam PF07244 Surface antigen variable number repeat 396 473 5.5E-10 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Pfam PF07244 Surface antigen variable number repeat 141 209 2.0E-9 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Pfam PF07244 Surface antigen variable number repeat 476 548 8.8E-14 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Pfam PF07244 Surface antigen variable number repeat 292 393 9.7E-10 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Pfam PF07244 Surface antigen variable number repeat 212 288 1.7E-12 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 130 877 21.137 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Gene3D G3DSA:3.10.20.310 291 394 1.9E-17 T 14-10-2018 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Gene3D G3DSA:3.10.20.310 136 209 1.5E-16 T 14-10-2018 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Pfam PF01103 Surface antigen 576 877 5.6E-77 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Gene3D G3DSA:3.10.20.310 475 549 4.0E-22 T 14-10-2018 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 Gene3D G3DSA:3.10.20.310 395 474 5.3E-14 T 14-10-2018 HL41_00950 d8132bdc3c5debd454b2a0b8676f17b9 877 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 140 877 3.9E-199 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 HL41_02340 60206044409c653e5ad7230c872d636e 325 SUPERFAMILY SSF51569 2 323 1.76E-151 T 14-10-2018 HL41_02340 60206044409c653e5ad7230c872d636e 325 PIRSF PIRSF001415 1 325 5.9E-161 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_02340 60206044409c653e5ad7230c872d636e 325 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 320 1.3E-160 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_02340 60206044409c653e5ad7230c872d636e 325 Gene3D G3DSA:3.20.20.70 2 323 9.4E-161 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_02340 60206044409c653e5ad7230c872d636e 325 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 14-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_02340 60206044409c653e5ad7230c872d636e 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 1.4E-61 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_02340 60206044409c653e5ad7230c872d636e 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 1.4E-61 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_02340 60206044409c653e5ad7230c872d636e 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 1.4E-61 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_02340 60206044409c653e5ad7230c872d636e 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 1.4E-61 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_02340 60206044409c653e5ad7230c872d636e 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 1.4E-61 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_02340 60206044409c653e5ad7230c872d636e 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 1.4E-61 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_02340 60206044409c653e5ad7230c872d636e 325 SMART SM01004 3 322 3.7E-253 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HL41_00765 11198f611ca62516b31ce4f43751cd66 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 8.1E-27 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_00765 11198f611ca62516b31ce4f43751cd66 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 21.971 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_00765 11198f611ca62516b31ce4f43751cd66 60 SUPERFAMILY SSF57829 1 56 1.65E-23 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 HL41_00765 11198f611ca62516b31ce4f43751cd66 60 Pfam PF01783 Ribosomal L32p protein family 2 57 9.4E-28 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_03600 b29d987c289a4e43f10dbd310cd9d14f 226 Hamap MF_00238 Cytidylate kinase [cmk]. 5 226 28.586 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 HL41_03600 b29d987c289a4e43f10dbd310cd9d14f 226 Pfam PF02224 Cytidylate kinase 7 224 5.6E-65 T 14-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 HL41_03600 b29d987c289a4e43f10dbd310cd9d14f 226 SUPERFAMILY SSF52540 3 226 8.03E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03600 b29d987c289a4e43f10dbd310cd9d14f 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 222 1.4E-59 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 HL41_03600 b29d987c289a4e43f10dbd310cd9d14f 226 Gene3D G3DSA:3.40.50.300 1 226 5.2E-72 T 14-10-2018 HL41_06120 f19f2ec2fc0d65c90471b9b46944d61e 326 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 211 224 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06120 f19f2ec2fc0d65c90471b9b46944d61e 326 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 53 68 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06120 f19f2ec2fc0d65c90471b9b46944d61e 326 Pfam PF00146 NADH dehydrogenase 16 320 1.9E-128 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06120 f19f2ec2fc0d65c90471b9b46944d61e 326 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 7 326 25.629 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 SMART SM00997 185 346 1.9E-109 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 2 136 3.1E-35 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 PIRSF PIRSF001109 1 418 1.3E-189 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 Gene3D G3DSA:3.40.50.1480 5 407 6.4E-179 T 14-10-2018 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 SUPERFAMILY SSF51735 185 347 3.79E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 74 88 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 139 417 1.2E-28 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 SMART SM00996 2 417 4.8E-148 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 418 48.5 T 14-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 Gene3D G3DSA:3.40.50.720 187 346 6.4E-179 T 14-10-2018 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 207 223 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 3 418 1.4E-204 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 185 345 3.0E-57 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HL41_04740 5a22b4feb17a1317ae1156d94fd2ca71 418 SUPERFAMILY SSF52283 1 418 7.94E-99 T 14-10-2018 HL41_05110 60ecf77cef85125a106fe05fff6baec4 213 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 35 200 1.0E-28 T 14-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like HL41_05110 60ecf77cef85125a106fe05fff6baec4 213 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 15 207 2.2E-14 T 14-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 HL41_05110 60ecf77cef85125a106fe05fff6baec4 213 Gene3D G3DSA:2.50.20.10 23 210 8.8E-42 T 14-10-2018 HL41_05110 60ecf77cef85125a106fe05fff6baec4 213 SUPERFAMILY SSF89392 24 209 3.73E-36 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX HL41_08350 2d4a1ac3ca60172e29afd593ccaba9c1 606 Pfam PF07715 TonB-dependent Receptor Plug Domain 35 142 5.6E-25 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain HL41_08350 2d4a1ac3ca60172e29afd593ccaba9c1 606 SUPERFAMILY SSF56935 15 606 2.02E-123 T 14-10-2018 HL41_08350 2d4a1ac3ca60172e29afd593ccaba9c1 606 Gene3D G3DSA:2.40.170.20 151 606 1.9E-102 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily HL41_08350 2d4a1ac3ca60172e29afd593ccaba9c1 606 Pfam PF00593 TonB dependent receptor 223 605 1.1E-53 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel HL41_08350 2d4a1ac3ca60172e29afd593ccaba9c1 606 Gene3D G3DSA:2.170.130.10 17 147 1.4E-34 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily HL41_01640 76499a2a9a07bd4055322187b8a7f371 254 Pfam PF13247 4Fe-4S dicluster domain 114 166 5.9E-13 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_01640 76499a2a9a07bd4055322187b8a7f371 254 Pfam PF13247 4Fe-4S dicluster domain 184 219 6.1E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_01640 76499a2a9a07bd4055322187b8a7f371 254 Gene3D G3DSA:3.30.70.20 51 253 2.5E-56 T 14-10-2018 HL41_01640 76499a2a9a07bd4055322187b8a7f371 254 SUPERFAMILY SSF54862 40 252 1.57E-53 T 14-10-2018 HL41_01640 76499a2a9a07bd4055322187b8a7f371 254 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 147 158 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07430 30b9dd0f1feb938aacdcc0dd28902875 216 SMART SM00478 40 199 1.9E-39 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HL41_07430 30b9dd0f1feb938aacdcc0dd28902875 216 Gene3D G3DSA:1.10.1670.10 139 216 2.5E-15 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 HL41_07430 30b9dd0f1feb938aacdcc0dd28902875 216 SUPERFAMILY SSF48150 7 215 4.24E-61 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 HL41_07430 30b9dd0f1feb938aacdcc0dd28902875 216 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 181 2.6E-20 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HL41_07430 30b9dd0f1feb938aacdcc0dd28902875 216 Gene3D G3DSA:1.10.340.30 23 138 3.7E-36 T 14-10-2018 HL41_07430 30b9dd0f1feb938aacdcc0dd28902875 216 PIRSF PIRSF001435 1 216 3.6E-74 T 14-10-2018 HL41_06425 ac64b89436e07f5d2b68ad59b21743e7 188 SUPERFAMILY SSF51182 3 183 2.14E-75 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily HL41_06425 ac64b89436e07f5d2b68ad59b21743e7 188 Gene3D G3DSA:2.60.120.10 3 188 4.3E-76 T 14-10-2018 IPR014710 RmlC-like jelly roll fold HL41_06425 ac64b89436e07f5d2b68ad59b21743e7 188 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 181 2.4E-75 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HL41_06425 ac64b89436e07f5d2b68ad59b21743e7 188 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 182 5.4E-80 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HL41_06425 ac64b89436e07f5d2b68ad59b21743e7 188 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 181 1.0E-61 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HL41_00610 5bb3d018bf324de8b6abda45ebb02c9b 320 Pfam PF00582 Universal stress protein family 174 307 3.8E-13 T 14-10-2018 IPR006016 UspA HL41_00610 5bb3d018bf324de8b6abda45ebb02c9b 320 Pfam PF00582 Universal stress protein family 19 169 1.9E-15 T 14-10-2018 IPR006016 UspA HL41_00610 5bb3d018bf324de8b6abda45ebb02c9b 320 SUPERFAMILY SSF52402 175 309 1.76E-15 T 14-10-2018 HL41_00610 5bb3d018bf324de8b6abda45ebb02c9b 320 Gene3D G3DSA:3.40.50.620 174 319 3.4E-17 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_00610 5bb3d018bf324de8b6abda45ebb02c9b 320 PRINTS PR01438 Universal stress protein signature 129 141 3.5E-5 T 14-10-2018 IPR006015 Universal stress protein A HL41_00610 5bb3d018bf324de8b6abda45ebb02c9b 320 PRINTS PR01438 Universal stress protein signature 147 169 3.5E-5 T 14-10-2018 IPR006015 Universal stress protein A HL41_00610 5bb3d018bf324de8b6abda45ebb02c9b 320 PRINTS PR01438 Universal stress protein signature 17 35 3.5E-5 T 14-10-2018 IPR006015 Universal stress protein A HL41_00610 5bb3d018bf324de8b6abda45ebb02c9b 320 SUPERFAMILY SSF52402 19 171 4.77E-19 T 14-10-2018 HL41_00610 5bb3d018bf324de8b6abda45ebb02c9b 320 Gene3D G3DSA:3.40.50.620 17 169 2.1E-22 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_05310 40d43d768334d5cd1f0085b7859f0b4a 210 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 99 1.0E-34 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 HL41_05310 40d43d768334d5cd1f0085b7859f0b4a 210 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 210 36.705 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HL41_05310 40d43d768334d5cd1f0085b7859f0b4a 210 SUPERFAMILY SSF55174 3 210 4.71E-74 T 14-10-2018 HL41_05310 40d43d768334d5cd1f0085b7859f0b4a 210 Gene3D G3DSA:1.10.1050.10 6 210 3.8E-90 T 14-10-2018 HL41_05310 40d43d768334d5cd1f0085b7859f0b4a 210 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 210 1.5E-77 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HL41_05310 40d43d768334d5cd1f0085b7859f0b4a 210 SMART SM00363 100 164 1.1E-20 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05310 40d43d768334d5cd1f0085b7859f0b4a 210 Gene3D G3DSA:3.10.290.10 99 195 3.8E-90 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HL41_05310 40d43d768334d5cd1f0085b7859f0b4a 210 SMART SM01390 3 99 2.7E-55 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 HL41_05310 40d43d768334d5cd1f0085b7859f0b4a 210 Pfam PF01479 S4 domain 100 147 3.1E-21 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 PRINTS PR00046 Major sigma-70 factor signature 408 423 3.6E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 PRINTS PR00046 Major sigma-70 factor signature 387 399 3.6E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 PRINTS PR00046 Major sigma-70 factor signature 264 272 3.6E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 PRINTS PR00046 Major sigma-70 factor signature 240 253 3.6E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 PRINTS PR00046 Major sigma-70 factor signature 423 434 3.6E-28 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 Pfam PF00140 Sigma-70 factor, region 1.2 98 126 2.7E-9 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 Gene3D G3DSA:1.10.10.10 289 363 2.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 Gene3D G3DSA:1.20.120.1810 93 285 9.3E-55 T 14-10-2018 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 408 434 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 240 253 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 Pfam PF04545 Sigma-70, region 4 384 436 1.3E-19 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 Pfam PF03979 Sigma-70 factor, region 1.1 10 68 7.1E-9 T 14-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 Pfam PF04539 Sigma-70 region 3 295 369 1.8E-17 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 SUPERFAMILY SSF88946 96 286 2.88E-50 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 Pfam PF04542 Sigma-70 region 2 216 285 1.2E-19 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 Gene3D G3DSA:1.10.220.120 3 60 6.3E-9 T 14-10-2018 HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 SUPERFAMILY SSF88659 350 441 8.04E-25 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 SUPERFAMILY SSF88659 289 359 8.28E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 Gene3D G3DSA:1.10.10.10 365 444 1.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_01870 bb4b20e60a57b02d2d75ef79ac7a1d83 447 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 212 436 5.4E-37 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 HL41_02595 e196edbf81ca6f8532bd4a70028a0097 263 PIRSF PIRSF003092 1 263 8.5E-79 T 14-10-2018 IPR025501 ATP binding protein MinD HL41_02595 e196edbf81ca6f8532bd4a70028a0097 263 Gene3D G3DSA:3.40.50.300 2 243 2.7E-50 T 14-10-2018 HL41_02595 e196edbf81ca6f8532bd4a70028a0097 263 SUPERFAMILY SSF52540 1 245 1.35E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02595 e196edbf81ca6f8532bd4a70028a0097 263 Pfam PF13614 AAA domain 1 158 6.1E-20 T 14-10-2018 IPR025669 AAA domain HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 SUPERFAMILY SSF68912 3 45 1.88E-5 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 Gene3D G3DSA:2.40.50.140 1 130 5.4E-43 T 14-10-2018 HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 SUPERFAMILY SSF50249 49 126 2.23E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 SMART SM00959 5 48 1.4E-5 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 SUPERFAMILY SSF52540 92 370 1.81E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 TIGRFAM TIGR00767 rho: transcription termination factor Rho 3 417 3.7E-200 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 1.8E-8 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 SMART SM00357 53 119 1.3E-15 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 SMART SM00382 168 354 1.3E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 417 221.993 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 157 362 6.6E-24 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 Gene3D G3DSA:3.40.50.300 131 416 2.5E-126 T 14-10-2018 HL41_05240 cc6496f971a1673bcc5706892c50ddbe 417 Pfam PF07497 Rho termination factor, RNA-binding domain 52 126 1.7E-29 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 HL41_01245 3337de2475873c1523e5dbaf460d0a72 243 Gene3D G3DSA:3.40.50.300 1 242 2.1E-56 T 14-10-2018 HL41_01245 3337de2475873c1523e5dbaf460d0a72 243 Pfam PF00005 ABC transporter 21 164 7.8E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_01245 3337de2475873c1523e5dbaf460d0a72 243 SUPERFAMILY SSF52540 4 223 8.67E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01245 3337de2475873c1523e5dbaf460d0a72 243 SMART SM00382 30 219 3.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_00175 06da51980e32f12a2abb3e030113db0b 147 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 142 4.5E-59 T 14-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 HL41_00175 06da51980e32f12a2abb3e030113db0b 147 SUPERFAMILY SSF89623 1 143 3.01E-58 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HL41_00175 06da51980e32f12a2abb3e030113db0b 147 Gene3D G3DSA:3.40.1400.10 1 143 3.5E-61 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HL41_00175 06da51980e32f12a2abb3e030113db0b 147 Pfam PF02502 Ribose/Galactose Isomerase 3 139 2.9E-56 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HL41_00175 06da51980e32f12a2abb3e030113db0b 147 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 143 2.3E-57 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HL41_00175 06da51980e32f12a2abb3e030113db0b 147 PIRSF PIRSF005384 1 147 9.9E-58 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HL41_03830 5fe38d44e75dfc0ec1d5c8b72a668917 251 Pfam PF11013 Protein of unknown function (DUF2851) 4 191 6.1E-12 T 14-10-2018 IPR021272 Protein of unknown function DUF2851 HL41_08340 d9939849f1f2b3d364b6dd152d150d94 224 SMART SM00448 2 115 4.4E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_08340 d9939849f1f2b3d364b6dd152d150d94 224 Gene3D G3DSA:3.40.50.2300 1 124 1.7E-34 T 14-10-2018 HL41_08340 d9939849f1f2b3d364b6dd152d150d94 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 220 5.6E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HL41_08340 d9939849f1f2b3d364b6dd152d150d94 224 Gene3D G3DSA:1.10.10.10 126 223 2.7E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_08340 d9939849f1f2b3d364b6dd152d150d94 224 SMART SM00862 147 220 2.7E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HL41_08340 d9939849f1f2b3d364b6dd152d150d94 224 SUPERFAMILY SSF52172 1 123 1.01E-36 T 14-10-2018 IPR011006 CheY-like superfamily HL41_08340 d9939849f1f2b3d364b6dd152d150d94 224 SUPERFAMILY SSF46894 127 221 4.54E-27 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HL41_08340 d9939849f1f2b3d364b6dd152d150d94 224 Pfam PF00072 Response regulator receiver domain 4 115 6.4E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 4 189 34.759 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 PRINTS PR00059 Ribosomal protein L6 signature 79 104 9.5E-25 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 PRINTS PR00059 Ribosomal protein L6 signature 154 175 9.5E-25 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 167 175 - T 14-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 Pfam PF00347 Ribosomal protein L6 14 90 3.6E-11 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 Pfam PF00347 Ribosomal protein L6 98 177 3.2E-18 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 SUPERFAMILY SSF56053 5 90 2.88E-17 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 PIRSF PIRSF002162 4 190 7.8E-50 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 Gene3D G3DSA:3.90.930.12 4 90 7.8E-23 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 5 189 2.8E-64 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 Gene3D G3DSA:3.90.930.12 91 193 2.1E-37 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05370 73012d9cf6ce2068dafd75dee6672830 195 SUPERFAMILY SSF56053 91 189 4.97E-32 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_01910 4d9dac8dcfc66e4cd58494d4ac0f54c2 294 SUPERFAMILY SSF53448 1 273 6.31E-57 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_01910 4d9dac8dcfc66e4cd58494d4ac0f54c2 294 Pfam PF00483 Nucleotidyl transferase 6 271 2.0E-27 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HL41_01910 4d9dac8dcfc66e4cd58494d4ac0f54c2 294 Gene3D G3DSA:3.90.550.10 1 293 3.7E-79 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_03050 3b5dd1c6d3976ba73ddaeadf8d4a835d 243 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_03050 3b5dd1c6d3976ba73ddaeadf8d4a835d 243 SUPERFAMILY SSF52540 4 224 4.46E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03050 3b5dd1c6d3976ba73ddaeadf8d4a835d 243 Gene3D G3DSA:3.40.50.300 1 240 2.8E-59 T 14-10-2018 HL41_03050 3b5dd1c6d3976ba73ddaeadf8d4a835d 243 Pfam PF00005 ABC transporter 20 162 4.4E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_03050 3b5dd1c6d3976ba73ddaeadf8d4a835d 243 SMART SM00382 29 211 1.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_00730 e32351f1a2e2da14f467ca019b014f21 318 SUPERFAMILY SSF53271 74 309 1.63E-63 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like HL41_00730 e32351f1a2e2da14f467ca019b014f21 318 SMART SM01400 9 125 2.7E-83 T 14-10-2018 HL41_00730 e32351f1a2e2da14f467ca019b014f21 318 Pfam PF14572 Phosphoribosyl synthetase-associated domain 203 317 5.2E-28 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HL41_00730 e32351f1a2e2da14f467ca019b014f21 318 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 133 148 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 HL41_00730 e32351f1a2e2da14f467ca019b014f21 318 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 1.9E-122 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HL41_00730 e32351f1a2e2da14f467ca019b014f21 318 Gene3D G3DSA:3.40.50.2020 12 306 3.3E-128 T 14-10-2018 HL41_00730 e32351f1a2e2da14f467ca019b014f21 318 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 9 318 49.263 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 HL41_00730 e32351f1a2e2da14f467ca019b014f21 318 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 125 1.2E-50 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HL41_00730 e32351f1a2e2da14f467ca019b014f21 318 Gene3D G3DSA:3.40.50.2020 152 294 3.3E-128 T 14-10-2018 HL41_00160 29ecf67ff2f6cf5e533fac4ecbb832ff 367 Pfam PF03739 Predicted permease YjgP/YjgQ family 11 351 7.3E-31 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 HL41_08030 79f8b890467360338620cd0ec35c65f8 459 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 456 3.7E-62 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 HL41_08030 79f8b890467360338620cd0ec35c65f8 459 SUPERFAMILY SSF53335 146 459 1.4E-76 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_08030 79f8b890467360338620cd0ec35c65f8 459 SUPERFAMILY SSF48013 8 160 2.09E-33 T 14-10-2018 IPR035926 NusB-like superfamily HL41_08030 79f8b890467360338620cd0ec35c65f8 459 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 10 458 1.6E-109 T 14-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 HL41_08030 79f8b890467360338620cd0ec35c65f8 459 Pfam PF01029 NusB family 8 132 8.5E-27 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HL41_08030 79f8b890467360338620cd0ec35c65f8 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 236 250 6.5E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HL41_08030 79f8b890467360338620cd0ec35c65f8 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 333 345 6.5E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HL41_08030 79f8b890467360338620cd0ec35c65f8 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 383 399 6.5E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HL41_08030 79f8b890467360338620cd0ec35c65f8 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 265 275 6.5E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HL41_08030 79f8b890467360338620cd0ec35c65f8 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 441 458 6.5E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HL41_08030 79f8b890467360338620cd0ec35c65f8 459 Gene3D G3DSA:1.10.940.10 4 150 2.1E-37 T 14-10-2018 IPR035926 NusB-like superfamily HL41_08030 79f8b890467360338620cd0ec35c65f8 459 Gene3D G3DSA:3.40.50.150 151 458 1.2E-86 T 14-10-2018 HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 SMART SM00825 Beta-ketoacyl synthase 5 412 1.3E-20 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 408 1.4E-199 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 7.0E-42 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 Gene3D G3DSA:3.40.47.10 255 399 6.4E-60 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 SUPERFAMILY SSF53901 213 410 2.8E-79 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 153 169 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 7.1E-64 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 SUPERFAMILY SSF53901 3 250 3.03E-80 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 Gene3D G3DSA:3.40.47.10 1 253 3.1E-97 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 HL41_00170 9d4c2f04c18e0acdd7bf76be8a32d4b2 413 PIRSF PIRSF000447 1 412 3.0E-192 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 HL41_06725 a05c88d2d9016d4f1f6d34d1d45bd887 133 SUPERFAMILY SSF54637 3 131 2.58E-34 T 14-10-2018 IPR029069 HotDog domain superfamily HL41_06725 a05c88d2d9016d4f1f6d34d1d45bd887 133 Pfam PF13279 Thioesterase-like superfamily 12 125 2.9E-11 T 14-10-2018 HL41_06725 a05c88d2d9016d4f1f6d34d1d45bd887 133 PIRSF PIRSF003230 1 133 1.1E-38 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HL41_06725 a05c88d2d9016d4f1f6d34d1d45bd887 133 Gene3D G3DSA:3.10.129.10 1 132 1.1E-33 T 14-10-2018 HL41_06725 a05c88d2d9016d4f1f6d34d1d45bd887 133 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 7 120 8.0E-24 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HL41_06780 e7bada71a9f53660e732909a1cd86ef3 273 SUPERFAMILY SSF53335 3 272 3.06E-63 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_06780 e7bada71a9f53660e732909a1cd86ef3 273 Gene3D G3DSA:2.30.140.10 2 52 1.3E-8 T 14-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HL41_06780 e7bada71a9f53660e732909a1cd86ef3 273 Pfam PF17284 Spermidine synthase tetramerisation domain 6 55 3.6E-9 T 14-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HL41_06780 e7bada71a9f53660e732909a1cd86ef3 273 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 80 93 - T 14-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HL41_06780 e7bada71a9f53660e732909a1cd86ef3 273 Gene3D G3DSA:3.40.50.150 53 272 4.2E-54 T 14-10-2018 HL41_06780 e7bada71a9f53660e732909a1cd86ef3 273 Pfam PF01564 Spermine/spermidine synthase domain 58 236 7.6E-45 T 14-10-2018 HL41_06780 e7bada71a9f53660e732909a1cd86ef3 273 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 5 273 30.775 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HL41_00120 488e69e4c6a1f9133a0a40272efacebd 151 SUPERFAMILY SSF46785 3 132 5.28E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_00120 488e69e4c6a1f9133a0a40272efacebd 151 Gene3D G3DSA:1.10.10.10 1 145 2.1E-40 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_00120 488e69e4c6a1f9133a0a40272efacebd 151 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site HL41_00120 488e69e4c6a1f9133a0a40272efacebd 151 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 131 1.5E-34 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type HL41_00120 488e69e4c6a1f9133a0a40272efacebd 151 Pfam PF02082 Transcriptional regulator 3 81 4.6E-26 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type HL41_02485 4ef17df0552896f3207bacbe63ccdac5 201 Gene3D G3DSA:1.10.1760.20 1 196 2.5E-46 T 14-10-2018 HL41_02485 4ef17df0552896f3207bacbe63ccdac5 201 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 195 6.9E-55 T 14-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 HL41_04330 333246a7c2299493dc5ad65fc4147174 72 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_04330 333246a7c2299493dc5ad65fc4147174 72 Pfam PF12838 4Fe-4S dicluster domain 10 59 4.9E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_04330 333246a7c2299493dc5ad65fc4147174 72 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 48 59 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_04330 333246a7c2299493dc5ad65fc4147174 72 SUPERFAMILY SSF54862 2 60 1.74E-15 T 14-10-2018 HL41_04330 333246a7c2299493dc5ad65fc4147174 72 Gene3D G3DSA:3.30.70.20 2 71 1.3E-13 T 14-10-2018 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 71 639 35.34 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 Gene3D G3DSA:3.30.980.10 76 225 1.2E-63 T 14-10-2018 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 328 534 1.2E-37 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 SUPERFAMILY SSF55186 68 244 6.93E-67 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 173 222 1.2E-15 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 Pfam PF03129 Anticodon binding domain 546 635 5.4E-20 T 14-10-2018 IPR004154 Anticodon-binding HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 SUPERFAMILY SSF55681 246 531 5.17E-97 T 14-10-2018 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 Gene3D G3DSA:3.30.54.20 135 190 1.2E-63 T 14-10-2018 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 Gene3D G3DSA:3.30.930.10 226 536 1.8E-124 T 14-10-2018 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 Gene3D G3DSA:3.40.50.800 537 646 1.8E-31 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 77 636 2.8E-227 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 SUPERFAMILY SSF52954 532 636 9.36E-29 T 14-10-2018 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 539 551 1.9E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 469 497 1.9E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 367 390 1.9E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 334 362 1.9E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 512 525 1.9E-51 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HL41_03425 abbe75d55bad4912ece50ed1888e7515 647 SMART SM00863 173 222 3.2E-26 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 HL41_07485 e3a7c196dffcd9324e0d98d648603485 287 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 181 202 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 HL41_07485 e3a7c196dffcd9324e0d98d648603485 287 Gene3D G3DSA:3.10.50.40 133 268 1.4E-37 T 14-10-2018 HL41_07485 e3a7c196dffcd9324e0d98d648603485 287 Pfam PF13616 PPIC-type PPIASE domain 134 243 1.1E-30 T 14-10-2018 HL41_07485 e3a7c196dffcd9324e0d98d648603485 287 SUPERFAMILY SSF109998 26 171 1.1E-15 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily HL41_07485 e3a7c196dffcd9324e0d98d648603485 287 SUPERFAMILY SSF54534 133 241 6.34E-31 T 14-10-2018 HL41_01955 ac9cc1b916c02f6c4a3f536572e1e2b8 427 PIRSF PIRSF000505 1 427 9.1E-126 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HL41_01955 ac9cc1b916c02f6c4a3f536572e1e2b8 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 17 425 4.1E-118 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HL41_01955 ac9cc1b916c02f6c4a3f536572e1e2b8 427 Gene3D G3DSA:3.65.10.10 23 239 5.4E-124 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HL41_01955 ac9cc1b916c02f6c4a3f536572e1e2b8 427 ProSitePatterns PS00885 EPSP synthase signature 2. 340 358 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HL41_01955 ac9cc1b916c02f6c4a3f536572e1e2b8 427 SUPERFAMILY SSF55205 15 425 2.09E-104 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HL41_01955 ac9cc1b916c02f6c4a3f536572e1e2b8 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 17 422 6.7E-107 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HL41_01955 ac9cc1b916c02f6c4a3f536572e1e2b8 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 12 427 30.04 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HL41_01955 ac9cc1b916c02f6c4a3f536572e1e2b8 427 Gene3D G3DSA:3.65.10.10 240 421 5.4E-124 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HL41_04975 3909a4b89338ad042f433b17ced0158c 269 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 176 257 2.2E-19 T 14-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 HL41_04975 3909a4b89338ad042f433b17ced0158c 269 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 32 65 1.2E-9 T 14-10-2018 IPR001451 Hexapeptide repeat HL41_04975 3909a4b89338ad042f433b17ced0158c 269 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 105 139 6.7E-9 T 14-10-2018 IPR001451 Hexapeptide repeat HL41_04975 3909a4b89338ad042f433b17ced0158c 269 PIRSF PIRSF000456 1 267 4.3E-104 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 HL41_04975 3909a4b89338ad042f433b17ced0158c 269 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 4 257 1.8E-96 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 HL41_04975 3909a4b89338ad042f433b17ced0158c 269 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 259 41.34 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 HL41_04975 3909a4b89338ad042f433b17ced0158c 269 SUPERFAMILY SSF51161 2 255 7.73E-77 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily HL41_04975 3909a4b89338ad042f433b17ced0158c 269 Gene3D G3DSA:2.160.10.10 1 191 1.6E-57 T 14-10-2018 HL41_04975 3909a4b89338ad042f433b17ced0158c 269 Gene3D G3DSA:1.20.1180.10 194 265 3.1E-13 T 14-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 HL41_05050 d547274ed05998e883d23ec445cd8114 237 Pfam PF01479 S4 domain 1 48 2.2E-13 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05050 d547274ed05998e883d23ec445cd8114 237 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 224 5.0E-43 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HL41_05050 d547274ed05998e883d23ec445cd8114 237 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 101 115 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HL41_05050 d547274ed05998e883d23ec445cd8114 237 Pfam PF00849 RNA pseudouridylate synthase 66 192 3.3E-14 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05050 d547274ed05998e883d23ec445cd8114 237 SUPERFAMILY SSF55174 1 55 4.54E-14 T 14-10-2018 HL41_05050 d547274ed05998e883d23ec445cd8114 237 Gene3D G3DSA:3.30.70.1560 130 211 1.7E-50 T 14-10-2018 HL41_05050 d547274ed05998e883d23ec445cd8114 237 Gene3D G3DSA:3.30.70.580 64 228 1.7E-50 T 14-10-2018 HL41_05050 d547274ed05998e883d23ec445cd8114 237 SUPERFAMILY SSF55120 62 229 7.67E-36 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 HL41_05050 d547274ed05998e883d23ec445cd8114 237 Gene3D G3DSA:3.10.290.10 1 63 7.2E-19 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HL41_05050 d547274ed05998e883d23ec445cd8114 237 SMART SM00363 1 60 2.0E-13 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_02800 ac38dd318364a07e82906b6c5fd95b4c 643 Gene3D G3DSA:3.30.450.20 162 288 1.7E-6 T 14-10-2018 HL41_02800 ac38dd318364a07e82906b6c5fd95b4c 643 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 442 608 1.7E-42 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02800 ac38dd318364a07e82906b6c5fd95b4c 643 Pfam PF17201 Cache 3/Cache 2 fusion domain 83 287 1.0E-50 T 14-10-2018 IPR033462 Cache 3/Cache 2 fusion domain HL41_02800 ac38dd318364a07e82906b6c5fd95b4c 643 SMART SM00283 381 642 4.2E-63 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02800 ac38dd318364a07e82906b6c5fd95b4c 643 Gene3D G3DSA:1.10.287.950 311 630 9.8E-68 T 14-10-2018 HL41_02800 ac38dd318364a07e82906b6c5fd95b4c 643 SUPERFAMILY SSF103190 86 193 8.24E-16 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily HL41_02800 ac38dd318364a07e82906b6c5fd95b4c 643 SUPERFAMILY SSF58104 342 642 2.18E-66 T 14-10-2018 HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 134 2.2E-30 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 Pfam PF00563 EAL domain 329 561 4.0E-49 T 14-10-2018 IPR001633 EAL domain HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 Gene3D G3DSA:3.20.20.450 322 574 7.0E-56 T 14-10-2018 IPR035919 EAL domain superfamily HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 Gene3D G3DSA:3.30.70.270 150 319 7.6E-27 T 14-10-2018 HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 Pfam PF01814 Hemerythrin HHE cation binding domain 14 124 4.1E-7 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 SMART SM00052 321 566 8.0E-40 T 14-10-2018 IPR001633 EAL domain HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 SUPERFAMILY SSF141868 327 571 7.32E-57 T 14-10-2018 IPR035919 EAL domain superfamily HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 SMART SM00267 135 311 2.2E-13 T 14-10-2018 IPR000160 GGDEF domain HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 SUPERFAMILY SSF55073 159 313 1.41E-24 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 Pfam PF00990 Diguanylate cyclase, GGDEF domain 161 307 2.1E-23 T 14-10-2018 IPR000160 GGDEF domain HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 162 310 2.6E-22 T 14-10-2018 IPR000160 GGDEF domain HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 SUPERFAMILY SSF47188 1 131 1.7E-29 T 14-10-2018 IPR035938 Hemerythrin-like superfamily HL41_02885 5ae211f80b8bdb6f8a7394bcb024ffa2 574 Gene3D G3DSA:1.20.120.50 2 140 9.1E-35 T 14-10-2018 IPR035938 Hemerythrin-like superfamily HL41_04440 1b033c4cb8bc75499763fb210e07f5ee 184 PIRSF PIRSF004682 1 178 4.3E-55 T 14-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 HL41_04440 1b033c4cb8bc75499763fb210e07f5ee 184 Pfam PF13242 HAD-hyrolase-like 101 176 1.9E-14 T 14-10-2018 HL41_04440 1b033c4cb8bc75499763fb210e07f5ee 184 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 145 5.6E-42 T 14-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 HL41_04440 1b033c4cb8bc75499763fb210e07f5ee 184 SUPERFAMILY SSF56784 1 180 1.13E-47 T 14-10-2018 IPR036412 HAD-like superfamily HL41_04440 1b033c4cb8bc75499763fb210e07f5ee 184 Gene3D G3DSA:3.40.50.1000 1 184 8.8E-56 T 14-10-2018 IPR023214 HAD superfamily HL41_04440 1b033c4cb8bc75499763fb210e07f5ee 184 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 148 2.6E-33 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Gene3D G3DSA:2.40.50.140 5 97 4.7E-13 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Pfam PF00575 S1 RNA binding domain 360 432 4.5E-19 T 14-10-2018 IPR003029 S1 domain GO:0003676 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Pfam PF00575 S1 RNA binding domain 191 260 5.6E-10 T 14-10-2018 IPR003029 S1 domain GO:0003676 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Pfam PF00575 S1 RNA binding domain 274 346 1.1E-14 T 14-10-2018 IPR003029 S1 domain GO:0003676 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Pfam PF00575 S1 RNA binding domain 446 524 1.0E-12 T 14-10-2018 IPR003029 S1 domain GO:0003676 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Pfam PF00575 S1 RNA binding domain 20 74 1.1E-6 T 14-10-2018 IPR003029 S1 domain GO:0003676 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SUPERFAMILY SSF50249 432 527 1.53E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_06680 4737979eb3504a8caba0b5df1898d786 563 PRINTS PR00681 Ribosomal protein S1 signature 22 40 3.7E-34 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 PRINTS PR00681 Ribosomal protein S1 signature 155 175 3.7E-34 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 PRINTS PR00681 Ribosomal protein S1 signature 212 233 3.7E-34 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 PRINTS PR00681 Ribosomal protein S1 signature 329 347 3.7E-34 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 PRINTS PR00681 Ribosomal protein S1 signature 40 54 3.7E-34 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 PRINTS PR00681 Ribosomal protein S1 signature 108 124 3.7E-34 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 PRINTS PR00681 Ribosomal protein S1 signature 290 309 3.7E-34 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Gene3D G3DSA:2.40.50.140 443 530 1.9E-16 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SUPERFAMILY SSF50249 7 108 4.29E-11 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SUPERFAMILY SSF50249 181 265 3.02E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SMART SM00316 447 525 1.2E-17 T 14-10-2018 IPR022967 RNA-binding domain, S1 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SMART SM00316 361 432 4.7E-25 T 14-10-2018 IPR022967 RNA-binding domain, S1 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SMART SM00316 20 87 5.3E-4 T 14-10-2018 IPR022967 RNA-binding domain, S1 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SMART SM00316 103 171 3.5E-4 T 14-10-2018 IPR022967 RNA-binding domain, S1 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SMART SM00316 275 346 9.4E-24 T 14-10-2018 IPR022967 RNA-binding domain, S1 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SMART SM00316 189 260 1.7E-12 T 14-10-2018 IPR022967 RNA-binding domain, S1 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SUPERFAMILY SSF50249 349 437 8.24E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Gene3D G3DSA:2.40.50.140 98 183 2.5E-6 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Gene3D G3DSA:2.40.50.140 271 355 5.6E-24 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Gene3D G3DSA:2.40.50.140 356 442 7.0E-28 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 Gene3D G3DSA:2.40.50.140 184 270 5.2E-16 T 14-10-2018 HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SUPERFAMILY SSF50249 257 363 1.07E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_06680 4737979eb3504a8caba0b5df1898d786 563 SUPERFAMILY SSF50249 103 184 2.81E-8 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_06095 78833a8ddb3325b5e55b2b60b2c60cc0 489 Pfam PF00361 Proton-conducting membrane transporter 133 417 9.3E-82 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06095 78833a8ddb3325b5e55b2b60b2c60cc0 489 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 326 345 3.3E-47 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06095 78833a8ddb3325b5e55b2b60b2c60cc0 489 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 3.3E-47 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06095 78833a8ddb3325b5e55b2b60b2c60cc0 489 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 3.3E-47 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06095 78833a8ddb3325b5e55b2b60b2c60cc0 489 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 169 193 3.3E-47 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06095 78833a8ddb3325b5e55b2b60b2c60cc0 489 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 378 404 3.3E-47 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06095 78833a8ddb3325b5e55b2b60b2c60cc0 489 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 9 486 6.3E-187 T 14-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_05590 3614f75faeb7cf5bbf50b083632d71e1 528 Gene3D G3DSA:3.20.20.70 3 327 1.5E-110 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_05590 3614f75faeb7cf5bbf50b083632d71e1 528 Pfam PF08502 LeuA allosteric (dimerisation) domain 377 520 3.4E-26 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05590 3614f75faeb7cf5bbf50b083632d71e1 528 SMART SM00917 376 521 2.4E-35 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05590 3614f75faeb7cf5bbf50b083632d71e1 528 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05590 3614f75faeb7cf5bbf50b083632d71e1 528 Pfam PF00682 HMGL-like 3 276 5.8E-52 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HL41_05590 3614f75faeb7cf5bbf50b083632d71e1 528 SUPERFAMILY SSF110921 413 516 2.48E-16 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HL41_05590 3614f75faeb7cf5bbf50b083632d71e1 528 SUPERFAMILY SSF51569 1 294 5.31E-83 T 14-10-2018 HL41_05590 3614f75faeb7cf5bbf50b083632d71e1 528 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 4 525 4.7E-233 T 14-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 HL41_05590 3614f75faeb7cf5bbf50b083632d71e1 528 Gene3D G3DSA:3.30.160.270 330 518 7.0E-6 T 14-10-2018 HL41_03980 34d06106d98d8eecae8d3b1eeeb6bb50 526 Gene3D G3DSA:3.20.20.70 103 519 1.9E-42 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_03980 34d06106d98d8eecae8d3b1eeeb6bb50 526 SUPERFAMILY SSF51395 101 514 8.79E-47 T 14-10-2018 HL41_03980 34d06106d98d8eecae8d3b1eeeb6bb50 526 Pfam PF01645 Conserved region in glutamate synthase 279 409 1.1E-12 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 HL41_06030 877a65739f6f73318341e1312688eb84 76 Pfam PF04023 FeoA domain 4 73 7.9E-17 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HL41_06030 877a65739f6f73318341e1312688eb84 76 SUPERFAMILY SSF50037 6 75 1.76E-20 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal HL41_06030 877a65739f6f73318341e1312688eb84 76 SMART SM00899 2 74 5.2E-19 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HL41_06030 877a65739f6f73318341e1312688eb84 76 Gene3D G3DSA:2.30.30.90 6 76 1.2E-24 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain HL41_07710 4ef17e9c620a6a763b574b63a167b629 245 Gene3D G3DSA:3.30.70.1890 2 120 1.8E-21 T 14-10-2018 HL41_07710 4ef17e9c620a6a763b574b63a167b629 245 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 47 241 4.2E-55 T 14-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 HL41_07710 4ef17e9c620a6a763b574b63a167b629 245 Gene3D G3DSA:3.30.70.1900 122 245 1.9E-42 T 14-10-2018 HL41_07710 4ef17e9c620a6a763b574b63a167b629 245 Pfam PF01881 CRISPR associated protein Cas6 95 242 6.2E-47 T 14-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 HL41_07710 4ef17e9c620a6a763b574b63a167b629 245 PIRSF PIRSF005054 1 245 8.9E-86 T 14-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 HL41_09075 611a7ec30f7f55a93efd89029608e8f8 346 Gene3D G3DSA:3.90.180.10 17 334 1.9E-74 T 14-10-2018 HL41_09075 611a7ec30f7f55a93efd89029608e8f8 346 SUPERFAMILY SSF50129 13 161 3.35E-48 T 14-10-2018 IPR011032 GroES-like superfamily HL41_09075 611a7ec30f7f55a93efd89029608e8f8 346 SMART SM00829 10 339 0.0036 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HL41_09075 611a7ec30f7f55a93efd89029608e8f8 346 Gene3D G3DSA:3.40.50.720 151 289 1.9E-74 T 14-10-2018 HL41_09075 611a7ec30f7f55a93efd89029608e8f8 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 135 3.7E-30 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HL41_09075 611a7ec30f7f55a93efd89029608e8f8 346 SUPERFAMILY SSF51735 141 308 1.17E-18 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_05085 76439f23ceb69bfeeb1fbd29123f2255 232 Gene3D G3DSA:3.30.420.40 6 221 1.7E-37 T 14-10-2018 HL41_05085 76439f23ceb69bfeeb1fbd29123f2255 232 SUPERFAMILY SSF53067 111 183 2.85E-6 T 14-10-2018 HL41_05085 76439f23ceb69bfeeb1fbd29123f2255 232 Gene3D G3DSA:3.30.420.40 97 187 1.7E-37 T 14-10-2018 HL41_05085 76439f23ceb69bfeeb1fbd29123f2255 232 Pfam PF00814 Glycoprotease family 33 149 3.5E-16 T 14-10-2018 IPR000905 Gcp-like domain HL41_05085 76439f23ceb69bfeeb1fbd29123f2255 232 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 6 220 1.6E-36 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 HL41_05085 76439f23ceb69bfeeb1fbd29123f2255 232 SUPERFAMILY SSF53067 6 105 2.2E-20 T 14-10-2018 HL41_02880 84bbc795d72d730b1ed8d63070b1d588 362 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 221 230 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 HL41_02880 84bbc795d72d730b1ed8d63070b1d588 362 Gene3D G3DSA:3.40.640.10 44 269 3.0E-109 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_02880 84bbc795d72d730b1ed8d63070b1d588 362 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 359 8.3E-106 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 HL41_02880 84bbc795d72d730b1ed8d63070b1d588 362 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 361 55.757 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 HL41_02880 84bbc795d72d730b1ed8d63070b1d588 362 Pfam PF00155 Aminotransferase class I and II 32 353 6.1E-62 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HL41_02880 84bbc795d72d730b1ed8d63070b1d588 362 SUPERFAMILY SSF53383 5 357 3.13E-83 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_02880 84bbc795d72d730b1ed8d63070b1d588 362 Gene3D G3DSA:3.90.1150.10 8 353 3.0E-109 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_01135 faa43430021a80b88ed3c24df27921db 285 Pfam PF01618 MotA/TolQ/ExbB proton channel family 135 235 7.3E-8 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel HL41_01135 faa43430021a80b88ed3c24df27921db 285 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 206 223 - T 14-10-2018 IPR000540 Flagellar motor protein MotA, conserved site HL41_01135 faa43430021a80b88ed3c24df27921db 285 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 1 282 1.1E-111 T 14-10-2018 IPR022522 Flagellar motor stator, MotA HL41_05445 3199997255eed999a6e5b867be03599f 211 Gene3D G3DSA:2.40.30.10 141 210 2.2E-12 T 14-10-2018 HL41_05445 3199997255eed999a6e5b867be03599f 211 Pfam PF00297 Ribosomal protein L3 107 187 1.4E-13 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05445 3199997255eed999a6e5b867be03599f 211 SUPERFAMILY SSF50447 3 208 1.59E-70 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_05445 3199997255eed999a6e5b867be03599f 211 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 3 211 35.261 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05445 3199997255eed999a6e5b867be03599f 211 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site HL41_05445 3199997255eed999a6e5b867be03599f 211 Gene3D G3DSA:2.40.50.620 33 99 3.9E-15 T 14-10-2018 HL41_05445 3199997255eed999a6e5b867be03599f 211 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 208 3.1E-82 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05820 06524a6f82c0504b5abe736d2220a124 131 PRINTS PR00162 Rieske 2Fe-2S subunit signature 69 80 5.8E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 HL41_05820 06524a6f82c0504b5abe736d2220a124 131 PRINTS PR00162 Rieske 2Fe-2S subunit signature 90 102 5.8E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 HL41_05820 06524a6f82c0504b5abe736d2220a124 131 PRINTS PR00162 Rieske 2Fe-2S subunit signature 102 114 5.8E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 HL41_05820 06524a6f82c0504b5abe736d2220a124 131 Gene3D G3DSA:2.102.10.10 36 130 8.0E-24 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HL41_05820 06524a6f82c0504b5abe736d2220a124 131 SUPERFAMILY SSF50022 46 128 6.81E-22 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 HL41_05820 06524a6f82c0504b5abe736d2220a124 131 Pfam PF00355 Rieske [2Fe-2S] domain 53 117 2.4E-13 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 HL41_06535 b8106305d51fbe75d52019cec618b444 369 Pfam PF12698 ABC-2 family transporter protein 23 362 7.0E-43 T 14-10-2018 HL41_06535 b8106305d51fbe75d52019cec618b444 369 Gene3D G3DSA:3.40.1710.10 43 156 2.4E-6 T 14-10-2018 HL41_00585 dcb1bb02792b47c42d0641143ec77c33 116 Pfam PF03692 Putative zinc- or iron-chelating domain 9 108 3.1E-14 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein HL41_06305 e4bff586d74e87038c910588fed0cfde 277 Gene3D G3DSA:3.90.550.10 1 199 2.9E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_06305 e4bff586d74e87038c910588fed0cfde 277 Pfam PF00535 Glycosyl transferase family 2 5 136 2.6E-16 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HL41_06305 e4bff586d74e87038c910588fed0cfde 277 SUPERFAMILY SSF53448 1 138 2.46E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_02450 2abb4b57f126890d8efe867dcfbde04a 340 Gene3D G3DSA:1.20.1420.30 33 310 1.9E-35 T 14-10-2018 HL41_02450 2abb4b57f126890d8efe867dcfbde04a 340 Pfam PF01699 Sodium/calcium exchanger protein 197 334 2.3E-10 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 HL41_02450 2abb4b57f126890d8efe867dcfbde04a 340 Pfam PF01699 Sodium/calcium exchanger protein 3 162 3.8E-16 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 HL41_02450 2abb4b57f126890d8efe867dcfbde04a 340 Gene3D G3DSA:1.20.58.1130 7 227 1.9E-35 T 14-10-2018 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 6.8E-28 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 PIRSF PIRSF016578 17 381 2.4E-20 T 14-10-2018 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 377 4.4E-47 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 SUPERFAMILY SSF56645 2 239 4.71E-80 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 Gene3D G3DSA:2.40.110.10 120 232 5.8E-42 T 14-10-2018 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 Gene3D G3DSA:1.10.540.10 1 118 1.2E-32 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 2.7E-28 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 Gene3D G3DSA:1.20.140.10 233 382 5.3E-54 T 14-10-2018 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 SUPERFAMILY SSF47203 226 381 2.74E-56 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 HL41_01210 3e8147f16129e5d59064f51de7d7a58c 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HL41_01145 4599e4ab0a0952fd2a291e0599714698 320 Gene3D G3DSA:3.90.1640.10 2 199 1.0E-68 T 14-10-2018 HL41_01145 4599e4ab0a0952fd2a291e0599714698 320 Pfam PF01368 DHH family 4 155 1.5E-25 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HL41_01145 4599e4ab0a0952fd2a291e0599714698 320 SUPERFAMILY SSF64182 4 317 6.67E-70 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily HL41_01145 4599e4ab0a0952fd2a291e0599714698 320 Pfam PF02833 DHHA2 domain 194 315 1.7E-19 T 14-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HL41_01145 4599e4ab0a0952fd2a291e0599714698 320 Gene3D G3DSA:3.10.310.20 200 319 1.5E-37 T 14-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HL41_01145 4599e4ab0a0952fd2a291e0599714698 320 SMART SM01131 191 317 9.2E-47 T 14-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HL41_06315 5277f4bfebf9a2bb29517c91fb0dc254 370 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 367 1.3E-121 T 14-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 HL41_06315 5277f4bfebf9a2bb29517c91fb0dc254 370 Gene3D G3DSA:3.40.50.2000 3 364 9.2E-147 T 14-10-2018 HL41_06315 5277f4bfebf9a2bb29517c91fb0dc254 370 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 367 1.2E-153 T 14-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 HL41_06315 5277f4bfebf9a2bb29517c91fb0dc254 370 Gene3D G3DSA:3.40.50.2000 189 353 9.2E-147 T 14-10-2018 HL41_06315 5277f4bfebf9a2bb29517c91fb0dc254 370 SUPERFAMILY SSF53756 1 369 4.9E-134 T 14-10-2018 HL41_01345 f45966a321e2b25d842d086e1d9ea83f 238 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 1.3E-99 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 HL41_01345 f45966a321e2b25d842d086e1d9ea83f 238 Gene3D G3DSA:3.40.1160.10 2 238 1.2E-80 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HL41_01345 f45966a321e2b25d842d086e1d9ea83f 238 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 45.185 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 HL41_01345 f45966a321e2b25d842d086e1d9ea83f 238 PIRSF PIRSF005650 1 238 1.1E-95 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 HL41_01345 f45966a321e2b25d842d086e1d9ea83f 238 Pfam PF00696 Amino acid kinase family 8 216 1.3E-31 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HL41_01345 f45966a321e2b25d842d086e1d9ea83f 238 SUPERFAMILY SSF53633 4 236 2.49E-72 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HL41_04360 6db0b65374a89fc5664776a4ce962d19 348 Pfam PF13439 Glycosyltransferase Family 4 18 119 1.8E-13 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 HL41_04360 6db0b65374a89fc5664776a4ce962d19 348 SUPERFAMILY SSF53756 10 339 6.81E-63 T 14-10-2018 HL41_04360 6db0b65374a89fc5664776a4ce962d19 348 Gene3D G3DSA:3.40.50.2000 12 338 9.5E-90 T 14-10-2018 HL41_04360 6db0b65374a89fc5664776a4ce962d19 348 Gene3D G3DSA:3.40.50.2000 157 332 9.5E-90 T 14-10-2018 HL41_04360 6db0b65374a89fc5664776a4ce962d19 348 Pfam PF00534 Glycosyl transferases group 1 171 310 3.3E-24 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 HL41_03770 afebc40b9994e82cafa6b59a0edd0896 71 Gene3D G3DSA:3.30.110.40 4 71 2.6E-17 T 14-10-2018 IPR036868 TusA-like domain superfamily HL41_03770 afebc40b9994e82cafa6b59a0edd0896 71 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 5 29 - T 14-10-2018 IPR001455 TusA-like domain HL41_03770 afebc40b9994e82cafa6b59a0edd0896 71 Pfam PF01206 Sulfurtransferase TusA 4 71 2.7E-19 T 14-10-2018 IPR001455 TusA-like domain HL41_03770 afebc40b9994e82cafa6b59a0edd0896 71 SUPERFAMILY SSF64307 3 71 2.88E-19 T 14-10-2018 IPR036868 TusA-like domain superfamily HL41_08665 1698f078a42d92fb0b9823452ff175f5 401 Gene3D G3DSA:1.10.645.20 12 401 2.9E-162 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08665 1698f078a42d92fb0b9823452ff175f5 401 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 6 401 47.505 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08665 1698f078a42d92fb0b9823452ff175f5 401 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 50 61 - T 14-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08665 1698f078a42d92fb0b9823452ff175f5 401 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 127 401 2.2E-108 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08665 1698f078a42d92fb0b9823452ff175f5 401 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 13 401 2.0E-154 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08665 1698f078a42d92fb0b9823452ff175f5 401 SUPERFAMILY SSF56762 23 400 5.49E-127 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_04090 5d6dfaa941277efa64b861701e64c55f 257 Gene3D G3DSA:3.40.1190.20 1 252 2.0E-66 T 14-10-2018 IPR029056 Ribokinase-like HL41_04090 5d6dfaa941277efa64b861701e64c55f 257 SUPERFAMILY SSF53613 2 244 3.12E-56 T 14-10-2018 IPR029056 Ribokinase-like HL41_04090 5d6dfaa941277efa64b861701e64c55f 257 Pfam PF08543 Phosphomethylpyrimidine kinase 10 243 4.6E-58 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 HL41_07960 251a293a58c988566e0875b3ccc12d1d 396 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 53 380 1.0E-53 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme HL41_07960 251a293a58c988566e0875b3ccc12d1d 396 Gene3D G3DSA:3.40.50.1100 11 208 4.0E-189 T 14-10-2018 HL41_07960 251a293a58c988566e0875b3ccc12d1d 396 Gene3D G3DSA:3.40.50.1100 55 386 4.0E-189 T 14-10-2018 HL41_07960 251a293a58c988566e0875b3ccc12d1d 396 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HL41_07960 251a293a58c988566e0875b3ccc12d1d 396 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 3 393 53.747 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HL41_07960 251a293a58c988566e0875b3ccc12d1d 396 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 8 392 2.3E-194 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HL41_07960 251a293a58c988566e0875b3ccc12d1d 396 SUPERFAMILY SSF53686 4 392 7.2E-155 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme HL41_07960 251a293a58c988566e0875b3ccc12d1d 396 PIRSF PIRSF001413 1 396 7.4E-169 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 13 177 2.0E-78 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 7.3E-69 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 SUPERFAMILY SSF51735 1 182 2.31E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 Gene3D G3DSA:3.40.50.720 1 181 2.4E-80 T 14-10-2018 HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 SUPERFAMILY SSF48179 183 328 1.21E-72 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 3.4E-148 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 45.905 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 Gene3D G3DSA:1.10.3730.40 182 332 2.0E-73 T 14-10-2018 HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 PIRSF PIRSF000116 3 204 8.4E-45 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HL41_08870 a8e08c5d2c398b26e1ac015f8a47f416 332 PIRSF PIRSF000116 201 330 4.3E-16 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HL41_03230 b2f66e6600731262d92e1592ee3c0be3 1150 SUPERFAMILY SSF57997 775 1001 6.21E-7 T 14-10-2018 HL41_03230 b2f66e6600731262d92e1592ee3c0be3 1150 Gene3D G3DSA:3.40.50.300 1 234 1.3E-53 T 14-10-2018 HL41_03230 b2f66e6600731262d92e1592ee3c0be3 1150 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1133 18.079 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 HL41_03230 b2f66e6600731262d92e1592ee3c0be3 1150 Gene3D G3DSA:3.40.50.300 893 1135 2.4E-42 T 14-10-2018 HL41_03230 b2f66e6600731262d92e1592ee3c0be3 1150 SUPERFAMILY SSF52540 3 1137 4.73E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03230 b2f66e6600731262d92e1592ee3c0be3 1150 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1124 4.0E-41 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal HL41_03230 b2f66e6600731262d92e1592ee3c0be3 1150 PIRSF PIRSF005719 1 511 1.6E-107 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein HL41_03230 b2f66e6600731262d92e1592ee3c0be3 1150 PIRSF PIRSF005719 584 1139 9.3E-99 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein HL41_03230 b2f66e6600731262d92e1592ee3c0be3 1150 SUPERFAMILY SSF57997 643 794 9.16E-5 T 14-10-2018 HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 SMART SM00052 495 733 3.8E-61 T 14-10-2018 IPR001633 EAL domain HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 Pfam PF00563 EAL domain 503 728 3.5E-59 T 14-10-2018 IPR001633 EAL domain HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 327 484 4.0E-17 T 14-10-2018 IPR000160 GGDEF domain HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 SUPERFAMILY SSF55073 334 487 4.47E-24 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 SMART SM00267 318 485 2.7E-10 T 14-10-2018 IPR000160 GGDEF domain HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 SUPERFAMILY SSF141868 500 741 1.16E-69 T 14-10-2018 IPR035919 EAL domain superfamily HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 Gene3D G3DSA:3.20.20.450 498 744 1.0E-71 T 14-10-2018 IPR035919 EAL domain superfamily HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 SUPERFAMILY SSF55781 30 204 6.98E-14 T 14-10-2018 HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 Gene3D G3DSA:3.30.70.270 324 497 1.6E-25 T 14-10-2018 HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 Gene3D G3DSA:3.30.450.40 40 209 2.8E-15 T 14-10-2018 IPR029016 GAF-like domain superfamily HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 Pfam PF13185 GAF domain 60 203 3.2E-11 T 14-10-2018 IPR003018 GAF domain GO:0005515 HL41_02415 8e9f9363f2fa155aebfc9f826b13c3b8 746 Pfam PF00990 Diguanylate cyclase, GGDEF domain 331 480 1.1E-20 T 14-10-2018 IPR000160 GGDEF domain HL41_01190 edd0135bc428168fe26aa4b2277c6aef 229 SUPERFAMILY SSF110997 151 226 1.57E-14 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 HL41_01190 edd0135bc428168fe26aa4b2277c6aef 229 Gene3D G3DSA:3.30.70.1070 152 227 3.6E-15 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 HL41_01190 edd0135bc428168fe26aa4b2277c6aef 229 Pfam PF05036 Sporulation related domain 151 226 1.4E-17 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 HL41_03775 9ce510c5bc728993b6f17e71c7e2cd55 188 Pfam PF11823 Protein of unknown function (DUF3343) 27 92 6.1E-15 T 14-10-2018 IPR021778 Domain of unknown function DUF3343 HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 205 556 1.2E-135 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 Pfam PF13167 GTP-binding GTPase N-terminal 221 308 2.1E-29 T 14-10-2018 IPR025121 GTPase HflX, N-terminal HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 Hamap MF_00900 GTPase HflX [hflX]. 223 570 44.7 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 395 553 9.1E-13 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 Pfam PF16360 GTP-binding GTPase Middle Region 310 388 1.0E-29 T 14-10-2018 IPR032305 GTP-binding protein, middle domain HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 Gene3D G3DSA:3.40.50.11060 215 336 1.9E-38 T 14-10-2018 HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 Pfam PF01926 50S ribosome-binding GTPase 396 514 9.5E-20 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 SUPERFAMILY SSF52540 395 562 5.73E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 Gene3D G3DSA:3.40.50.300 394 562 1.9E-41 T 14-10-2018 HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 396 416 3.4E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_03625 11f361f4732da0981f8ae0e8ec4af10f 591 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 463 481 3.4E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_07790 7b1f3d21af8647e2661dac9e793fb15b 98 Pfam PF01909 Nucleotidyltransferase domain 12 93 3.3E-14 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 HL41_07790 7b1f3d21af8647e2661dac9e793fb15b 98 SUPERFAMILY SSF81301 1 89 3.93E-24 T 14-10-2018 HL41_07790 7b1f3d21af8647e2661dac9e793fb15b 98 Gene3D G3DSA:3.30.460.10 1 96 3.5E-21 T 14-10-2018 HL41_06100 7f52ed2d28578c7f280906377a666063 650 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 16 645 2.3E-225 T 14-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06100 7f52ed2d28578c7f280906377a666063 650 Pfam PF00361 Proton-conducting membrane transporter 143 435 2.2E-87 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06100 7f52ed2d28578c7f280906377a666063 650 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 131 2.0E-21 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06100 7f52ed2d28578c7f280906377a666063 650 Pfam PF01010 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus 464 583 3.8E-7 T 14-10-2018 IPR002128 NADH:ubiquinone/plastoquinone oxidoreductase, chloroplast chain 5, C-terminal HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 282 304 1.3E-8 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 68 92 1.3E-8 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 46 65 1.3E-8 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 435 457 1.3E-8 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 94 114 1.3E-8 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 120 140 1.5E-66 T 14-10-2018 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 167 188 1.5E-66 T 14-10-2018 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 332 344 1.5E-66 T 14-10-2018 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 92 117 1.5E-66 T 14-10-2018 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 242 263 1.5E-66 T 14-10-2018 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 436 455 1.5E-66 T 14-10-2018 HL41_06100 7f52ed2d28578c7f280906377a666063 650 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 264 290 1.5E-66 T 14-10-2018 HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 ProSitePatterns PS00056 Ribosomal protein S17 signature. 57 69 - T 14-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 Pfam PF00366 Ribosomal protein S17 11 76 1.8E-35 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 76 6.5E-38 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 1.3E-13 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 1.3E-13 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 1.3E-13 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 SUPERFAMILY SSF50249 5 85 1.76E-36 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 Gene3D G3DSA:2.40.50.140 5 85 4.4E-39 T 14-10-2018 HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 6 81 26.253 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05400 a01ff6a7af052088b4f7ccffb75a85c0 96 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 6 76 1.0E-24 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_04160 1b12ba5d53f62bba25f2f959ad7360d2 436 Gene3D G3DSA:3.30.460.10 17 178 4.4E-33 T 14-10-2018 HL41_04160 1b12ba5d53f62bba25f2f959ad7360d2 436 Gene3D G3DSA:1.10.3090.10 180 430 2.8E-40 T 14-10-2018 HL41_04160 1b12ba5d53f62bba25f2f959ad7360d2 436 Pfam PF01743 Poly A polymerase head domain 46 182 1.2E-20 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 HL41_04160 1b12ba5d53f62bba25f2f959ad7360d2 436 SUPERFAMILY SSF81301 29 179 2.83E-24 T 14-10-2018 HL41_04160 1b12ba5d53f62bba25f2f959ad7360d2 436 SUPERFAMILY SSF81891 188 434 9.03E-31 T 14-10-2018 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 Pfam PF00694 Aconitase C-terminal domain 510 581 4.4E-23 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 Gene3D G3DSA:3.20.19.10 453 645 4.0E-46 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 5 644 1.0E-286 T 14-10-2018 IPR006250 Aconitase, putative HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 Pfam PF00330 Aconitase family (aconitate hydratase) 8 407 5.3E-103 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 SUPERFAMILY SSF53732 1 420 6.54E-143 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 SUPERFAMILY SSF52016 439 644 4.91E-54 T 14-10-2018 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 PRINTS PR00415 Aconitase family signature 124 139 8.1E-23 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 PRINTS PR00415 Aconitase family signature 186 199 8.1E-23 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 PRINTS PR00415 Aconitase family signature 349 362 8.1E-23 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 PRINTS PR00415 Aconitase family signature 200 213 8.1E-23 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 PRINTS PR00415 Aconitase family signature 90 98 8.1E-23 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 PRINTS PR00415 Aconitase family signature 110 123 8.1E-23 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 Gene3D G3DSA:3.30.499.10 270 444 4.4E-41 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 HL41_00300 4c6b7fcc1037e1b79871922d8cd6c3d9 646 Gene3D G3DSA:3.30.499.20 5 267 3.0E-87 T 14-10-2018 HL41_08745 89f84564e839455bb955d2cdd79b83b3 538 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 288 528 1.7E-44 T 14-10-2018 HL41_08745 89f84564e839455bb955d2cdd79b83b3 538 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 34 262 6.3E-32 T 14-10-2018 HL41_08745 89f84564e839455bb955d2cdd79b83b3 538 SUPERFAMILY SSF53850 53 195 1.41E-14 T 14-10-2018 HL41_08745 89f84564e839455bb955d2cdd79b83b3 538 SUPERFAMILY SSF53850 305 508 2.04E-20 T 14-10-2018 HL41_08745 89f84564e839455bb955d2cdd79b83b3 538 Gene3D G3DSA:3.40.190.10 117 218 9.8E-23 T 14-10-2018 HL41_08745 89f84564e839455bb955d2cdd79b83b3 538 Gene3D G3DSA:3.40.190.10 379 484 4.1E-39 T 14-10-2018 HL41_08745 89f84564e839455bb955d2cdd79b83b3 538 Gene3D G3DSA:3.40.190.10 288 508 4.1E-39 T 14-10-2018 HL41_08745 89f84564e839455bb955d2cdd79b83b3 538 SMART SM00062 284 519 0.0079 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HL41_08745 89f84564e839455bb955d2cdd79b83b3 538 Gene3D G3DSA:3.40.190.10 34 242 9.8E-23 T 14-10-2018 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 Gene3D G3DSA:3.40.50.620 23 525 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 SUPERFAMILY SSF47323 575 827 1.25E-60 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 812 876 5.5E-14 T 14-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 SUPERFAMILY SSF50677 192 340 1.83E-62 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 Gene3D G3DSA:1.10.287.380 805 877 1.1E-16 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 Hamap MF_02004 Valine--tRNA ligase [valS]. 3 877 15.833 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 Gene3D G3DSA:1.10.730.10 3 740 0.0 T 14-10-2018 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 564 1.0E-209 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 SUPERFAMILY SSF52374 2 572 1.25E-147 T 14-10-2018 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 PRINTS PR00986 Valyl-tRNA synthetase signature 445 466 3.2E-37 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 PRINTS PR00986 Valyl-tRNA synthetase signature 37 48 3.2E-37 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 PRINTS PR00986 Valyl-tRNA synthetase signature 476 494 3.2E-37 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 PRINTS PR00986 Valyl-tRNA synthetase signature 346 359 3.2E-37 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 3.2E-37 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 44 55 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 Pfam PF08264 Anticodon-binding domain of tRNA 608 753 1.7E-38 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 SUPERFAMILY SSF46589 812 876 9.42E-14 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 Gene3D G3DSA:3.90.740.10 176 343 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HL41_03240 d072aea81f7ddb9a87d4feaf73c3473d 879 TIGRFAM TIGR00422 valS: valine--tRNA ligase 4 857 0.0 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HL41_03915 b866365a8b959f0f62ca0e99ee3678b5 1105 SMART SM00490 496 576 1.3E-24 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_03915 b866365a8b959f0f62ca0e99ee3678b5 1105 Pfam PF00271 Helicase conserved C-terminal domain 466 576 1.3E-20 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_03915 b866365a8b959f0f62ca0e99ee3678b5 1105 Gene3D G3DSA:3.40.50.300 406 607 2.2E-47 T 14-10-2018 HL41_03915 b866365a8b959f0f62ca0e99ee3678b5 1105 Gene3D G3DSA:3.40.50.10810 98 405 3.2E-60 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily HL41_03915 b866365a8b959f0f62ca0e99ee3678b5 1105 SUPERFAMILY SSF52540 321 616 1.52E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03915 b866365a8b959f0f62ca0e99ee3678b5 1105 SUPERFAMILY SSF52540 84 298 4.85E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03915 b866365a8b959f0f62ca0e99ee3678b5 1105 SMART SM00487 98 299 1.4E-19 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HL41_03915 b866365a8b959f0f62ca0e99ee3678b5 1105 Pfam PF00176 SNF2 family N-terminal domain 123 360 6.5E-18 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 HL41_03915 b866365a8b959f0f62ca0e99ee3678b5 1105 Pfam PF13020 Domain of unknown function (DUF3883) 985 1072 8.7E-23 T 14-10-2018 IPR024975 Domain of unknown function DUF3883 HL41_04730 6f0cd67d9f2cdd997b02139a3dabfa58 402 Pfam PF02371 Transposase IS116/IS110/IS902 family 263 347 1.4E-23 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HL41_04730 6f0cd67d9f2cdd997b02139a3dabfa58 402 Pfam PF01548 Transposase 5 156 3.3E-27 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HL41_07400 1245e312f99f3040b08e813131014ddf 227 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 3 227 31.825 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 HL41_07400 1245e312f99f3040b08e813131014ddf 227 Pfam PF01209 ubiE/COQ5 methyltransferase family 2 227 3.4E-55 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 HL41_07400 1245e312f99f3040b08e813131014ddf 227 SUPERFAMILY SSF53335 11 222 1.86E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_07400 1245e312f99f3040b08e813131014ddf 227 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 135 149 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 HL41_07400 1245e312f99f3040b08e813131014ddf 227 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 8 227 6.9E-65 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 HL41_07400 1245e312f99f3040b08e813131014ddf 227 Gene3D G3DSA:3.40.50.150 14 227 3.5E-54 T 14-10-2018 HL41_08915 ccaaac8e7bdce3b3a66dbb9aab9568d3 163 Gene3D G3DSA:3.30.720.40 68 147 5.8E-26 T 14-10-2018 IPR038465 APS reductase, beta subunit, C-terminal domain superfamily HL41_08915 ccaaac8e7bdce3b3a66dbb9aab9568d3 163 Pfam PF13187 4Fe-4S dicluster domain 9 62 1.6E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_08915 ccaaac8e7bdce3b3a66dbb9aab9568d3 163 TIGRFAM TIGR02060 aprB: adenylylsulfate reductase, beta subunit 1 132 8.8E-65 T 14-10-2018 IPR011802 Adenylylsulphate reductase, beta subunit HL41_08915 ccaaac8e7bdce3b3a66dbb9aab9568d3 163 SUPERFAMILY SSF54862 4 110 5.9E-24 T 14-10-2018 HL41_08915 ccaaac8e7bdce3b3a66dbb9aab9568d3 163 Pfam PF12139 Adenosine-5'-phosphosulfate reductase beta subunit 64 136 3.5E-27 T 14-10-2018 IPR022738 Adenylylsulphate reductase, beta subunit, C-terminal HL41_08915 ccaaac8e7bdce3b3a66dbb9aab9568d3 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08915 ccaaac8e7bdce3b3a66dbb9aab9568d3 163 Gene3D G3DSA:3.30.70.20 2 67 5.8E-29 T 14-10-2018 HL41_09015 b530f2fb38b0de88a030e0d208c18bdb 1075 Gene3D G3DSA:2.30.42.10 34 130 4.2E-14 T 14-10-2018 HL41_09015 b530f2fb38b0de88a030e0d208c18bdb 1075 SUPERFAMILY SSF50156 37 110 2.1E-13 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 HL41_09015 b530f2fb38b0de88a030e0d208c18bdb 1075 SMART SM00228 20 98 1.0E-8 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_09015 b530f2fb38b0de88a030e0d208c18bdb 1075 Pfam PF13180 PDZ domain 36 100 2.9E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_04135 5527fb102305cd3aaf965a484608b450 422 Pfam PF02464 Competence-damaged protein 249 401 3.6E-54 T 14-10-2018 IPR008136 CinA, C-terminal HL41_04135 5527fb102305cd3aaf965a484608b450 422 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 255 400 3.1E-45 T 14-10-2018 IPR008136 CinA, C-terminal HL41_04135 5527fb102305cd3aaf965a484608b450 422 SUPERFAMILY SSF53218 3 200 2.22E-29 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily HL41_04135 5527fb102305cd3aaf965a484608b450 422 Pfam PF00994 Probable molybdopterin binding domain 5 165 2.0E-23 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_04135 5527fb102305cd3aaf965a484608b450 422 SMART SM00852 4 167 5.1E-22 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_04135 5527fb102305cd3aaf965a484608b450 422 PIRSF PIRSF006728 1 408 5.6E-99 T 14-10-2018 IPR008135 Competence-induced protein CinA HL41_04135 5527fb102305cd3aaf965a484608b450 422 Gene3D G3DSA:3.40.980.10 2 164 2.1E-36 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily HL41_04135 5527fb102305cd3aaf965a484608b450 422 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 422 109.468 T 14-10-2018 IPR008135 Competence-induced protein CinA HL41_04135 5527fb102305cd3aaf965a484608b450 422 Gene3D G3DSA:3.90.950.20 239 405 2.2E-54 T 14-10-2018 IPR036653 CinA-like, C-terminal HL41_04135 5527fb102305cd3aaf965a484608b450 422 SUPERFAMILY SSF142433 244 402 4.45E-54 T 14-10-2018 IPR036653 CinA-like, C-terminal HL41_00270 8c7ce8e129facc1f6abd39bb595e4c86 370 SUPERFAMILY SSF51412 8 303 7.94E-49 T 14-10-2018 HL41_00270 8c7ce8e129facc1f6abd39bb595e4c86 370 Pfam PF03060 Nitronate monooxygenase 8 361 8.9E-57 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 HL41_00270 8c7ce8e129facc1f6abd39bb595e4c86 370 Gene3D G3DSA:3.20.20.70 7 366 1.8E-62 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_09110 b44239298d8310e090ea96829caac638 604 SUPERFAMILY SSF53300 416 588 3.71E-23 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily HL41_09110 b44239298d8310e090ea96829caac638 604 Gene3D G3DSA:3.40.50.410 411 598 7.9E-21 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily HL41_09110 b44239298d8310e090ea96829caac638 604 SUPERFAMILY SSF52540 2 279 1.58E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_09110 b44239298d8310e090ea96829caac638 604 SMART SM00382 24 170 9.6E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_09110 b44239298d8310e090ea96829caac638 604 Pfam PF07728 AAA domain (dynein-related subfamily) 28 159 1.7E-10 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 HL41_09110 b44239298d8310e090ea96829caac638 604 Gene3D G3DSA:1.10.8.80 202 291 4.9E-17 T 14-10-2018 HL41_09110 b44239298d8310e090ea96829caac638 604 Gene3D G3DSA:3.40.50.300 1 165 1.1E-40 T 14-10-2018 HL41_09110 b44239298d8310e090ea96829caac638 604 SMART SM00327 413 588 1.2E-15 T 14-10-2018 IPR002035 von Willebrand factor, type A HL41_09110 b44239298d8310e090ea96829caac638 604 Pfam PF13519 von Willebrand factor type A domain 416 522 7.9E-14 T 14-10-2018 IPR002035 von Willebrand factor, type A HL41_00875 ac1b29941eb6e0690f83e188afa13e8f 153 Gene3D G3DSA:2.30.130.90 1 152 2.6E-5 T 14-10-2018 HL41_06605 fa7cccaca6be934ba7849a8277c68d62 345 SUPERFAMILY SSF52418 78 341 5.1E-78 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 HL41_06605 fa7cccaca6be934ba7849a8277c68d62 345 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 339 33.742 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 HL41_06605 fa7cccaca6be934ba7849a8277c68d62 345 SUPERFAMILY SSF47648 1 69 1.15E-11 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 HL41_06605 fa7cccaca6be934ba7849a8277c68d62 345 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 9 338 1.2E-107 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 HL41_06605 fa7cccaca6be934ba7849a8277c68d62 345 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 64 2.2E-9 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 HL41_06605 fa7cccaca6be934ba7849a8277c68d62 345 Gene3D G3DSA:3.40.1030.10 74 322 2.0E-110 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 HL41_06605 fa7cccaca6be934ba7849a8277c68d62 345 Gene3D G3DSA:1.20.970.10 9 187 2.0E-110 T 14-10-2018 HL41_06605 fa7cccaca6be934ba7849a8277c68d62 345 Pfam PF00591 Glycosyl transferase family, a/b domain 79 328 3.3E-83 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HL41_05125 fa9328ed9f82403b78972983140e8412 649 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 328 411 2.7E-12 T 14-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HL41_05125 fa9328ed9f82403b78972983140e8412 649 SUPERFAMILY SSF48310 244 635 1.57E-41 T 14-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HL41_05125 fa9328ed9f82403b78972983140e8412 649 Gene3D G3DSA:3.60.9.10 2 233 4.7E-17 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily HL41_05125 fa9328ed9f82403b78972983140e8412 649 SUPERFAMILY SSF56228 4 234 6.02E-29 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily HL41_05125 fa9328ed9f82403b78972983140e8412 649 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 5 230 8.6E-32 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HL41_05125 fa9328ed9f82403b78972983140e8412 649 SMART SM00790 2 231 2.0E-11 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HL41_05125 fa9328ed9f82403b78972983140e8412 649 Gene3D G3DSA:1.10.569.10 306 480 2.9E-13 T 14-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 HL41_00225 98977de444fce74323ef177b60d70948 126 Pfam PF02472 Biopolymer transport protein ExbD/TolR 7 123 4.6E-22 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 HL41_05700 6fd72504cae20367b956ae45fbd91328 225 Gene3D G3DSA:3.40.50.300 2 224 7.2E-59 T 14-10-2018 HL41_05700 6fd72504cae20367b956ae45fbd91328 225 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_05700 6fd72504cae20367b956ae45fbd91328 225 SUPERFAMILY SSF52540 4 219 4.58E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05700 6fd72504cae20367b956ae45fbd91328 225 Pfam PF00005 ABC transporter 20 167 1.8E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_05700 6fd72504cae20367b956ae45fbd91328 225 SMART SM00382 29 216 8.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_07490 3c808f0128102eceb4e1e7a0a74b91a9 257 SUPERFAMILY SSF51161 100 244 4.32E-21 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily HL41_07490 3c808f0128102eceb4e1e7a0a74b91a9 257 Gene3D G3DSA:2.160.10.10 81 245 1.1E-35 T 14-10-2018 HL41_08025 5a2f7371d38fa028bffdbdf7061d0b75 173 Gene3D G3DSA:1.20.1260.10 1 164 3.4E-56 T 14-10-2018 IPR012347 Ferritin-like HL41_08025 5a2f7371d38fa028bffdbdf7061d0b75 173 SUPERFAMILY SSF47240 1 160 1.16E-61 T 14-10-2018 IPR009078 Ferritin-like superfamily HL41_08025 5a2f7371d38fa028bffdbdf7061d0b75 173 Pfam PF00210 Ferritin-like domain 7 143 1.9E-44 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 HL41_08835 e35525171f86a422988e6deb158be36a 130 PRINTS PR00502 NUDIX hydrolase family signature 45 60 3.2E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HL41_08835 e35525171f86a422988e6deb158be36a 130 PRINTS PR00502 NUDIX hydrolase family signature 31 45 3.2E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HL41_08835 e35525171f86a422988e6deb158be36a 130 Pfam PF00293 NUDIX domain 9 120 1.6E-23 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HL41_08835 e35525171f86a422988e6deb158be36a 130 Gene3D G3DSA:3.90.79.10 1 129 1.6E-37 T 14-10-2018 HL41_08835 e35525171f86a422988e6deb158be36a 130 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HL41_08835 e35525171f86a422988e6deb158be36a 130 SUPERFAMILY SSF55811 5 123 2.17E-32 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 HL41_04255 bc9deeee52903a48b796ef51071fb4f3 193 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 5 190 3.4E-57 T 14-10-2018 IPR014856 PIN-domain ribonuclease HL41_04255 bc9deeee52903a48b796ef51071fb4f3 193 SUPERFAMILY SSF88723 78 182 8.97E-6 T 14-10-2018 IPR029060 PIN-like domain superfamily HL41_04255 bc9deeee52903a48b796ef51071fb4f3 193 Pfam PF08745 PINc domain ribonuclease 5 189 7.6E-58 T 14-10-2018 IPR014856 PIN-domain ribonuclease HL41_04255 bc9deeee52903a48b796ef51071fb4f3 193 Hamap MF_01078 UPF0278 protein . 3 193 28.069 T 14-10-2018 IPR014856 PIN-domain ribonuclease HL41_05500 3a409dc5af5f4113d920112c3535eb2d 412 PIRSF PIRSF000412 1 412 3.7E-172 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HL41_05500 3a409dc5af5f4113d920112c3535eb2d 412 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HL41_05500 3a409dc5af5f4113d920112c3535eb2d 412 SUPERFAMILY SSF53383 2 411 2.2E-179 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_05500 3a409dc5af5f4113d920112c3535eb2d 412 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 53.824 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HL41_05500 3a409dc5af5f4113d920112c3535eb2d 412 Gene3D G3DSA:3.40.640.10 33 283 8.4E-190 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_05500 3a409dc5af5f4113d920112c3535eb2d 412 Pfam PF00464 Serine hydroxymethyltransferase 4 380 1.7E-172 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HL41_05500 3a409dc5af5f4113d920112c3535eb2d 412 Gene3D G3DSA:3.90.1150.10 6 389 8.4E-190 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_01760 518684f6262fd9a470f5d9c682bcc2d2 200 Gene3D G3DSA:1.10.10.60 1 54 3.2E-18 T 14-10-2018 HL41_01760 518684f6262fd9a470f5d9c682bcc2d2 200 SUPERFAMILY SSF46689 3 59 4.89E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_01760 518684f6262fd9a470f5d9c682bcc2d2 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.3E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HL41_01760 518684f6262fd9a470f5d9c682bcc2d2 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.3E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HL41_01760 518684f6262fd9a470f5d9c682bcc2d2 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 1.1E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HL41_01760 518684f6262fd9a470f5d9c682bcc2d2 200 Gene3D G3DSA:1.10.357.10 57 195 7.5E-22 T 14-10-2018 HL41_01760 518684f6262fd9a470f5d9c682bcc2d2 200 SUPERFAMILY SSF48498 81 192 6.12E-15 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily HL41_07385 b5d250710efbfc6caf533cf674085736 287 SUPERFAMILY SSF103501 3 240 2.22E-21 T 14-10-2018 IPR036197 NarG-like superfamily HL41_07385 b5d250710efbfc6caf533cf674085736 287 Pfam PF02665 Nitrate reductase gamma subunit 134 238 6.7E-7 T 14-10-2018 IPR023234 NarG-like domain HL41_07385 b5d250710efbfc6caf533cf674085736 287 Gene3D G3DSA:1.20.950.20 84 240 7.4E-10 T 14-10-2018 HL41_05360 83ae39833187033e39c184a00fe50b4d 167 Gene3D G3DSA:3.30.160.20 4 70 1.5E-31 T 14-10-2018 HL41_05360 83ae39833187033e39c184a00fe50b4d 167 Gene3D G3DSA:3.30.230.10 71 163 1.7E-37 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HL41_05360 83ae39833187033e39c184a00fe50b4d 167 SUPERFAMILY SSF54768 6 73 8.68E-24 T 14-10-2018 HL41_05360 83ae39833187033e39c184a00fe50b4d 167 SUPERFAMILY SSF54211 76 156 1.31E-26 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HL41_05360 83ae39833187033e39c184a00fe50b4d 167 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 160 34.977 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HL41_05360 83ae39833187033e39c184a00fe50b4d 167 Pfam PF00333 Ribosomal protein S5, N-terminal domain 9 72 2.1E-30 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 HL41_05360 83ae39833187033e39c184a00fe50b4d 167 Pfam PF03719 Ribosomal protein S5, C-terminal domain 84 154 2.3E-31 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 HL41_05360 83ae39833187033e39c184a00fe50b4d 167 ProSitePatterns PS00585 Ribosomal protein S5 signature. 25 57 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site HL41_05360 83ae39833187033e39c184a00fe50b4d 167 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 6 160 2.6E-68 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HL41_00660 eaea62dbe296445289411b0ed56c1798 197 SUPERFAMILY SSF55821 5 195 2.62E-55 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily HL41_00660 eaea62dbe296445289411b0ed56c1798 197 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 192 3.3E-45 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 HL41_00660 eaea62dbe296445289411b0ed56c1798 197 Gene3D G3DSA:3.90.870.10 2 197 4.3E-61 T 14-10-2018 HL41_00660 eaea62dbe296445289411b0ed56c1798 197 Pfam PF01300 Telomere recombination 11 185 4.4E-49 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 HL41_04205 5348f40c1a133e8f650417e213394239 413 Pfam PF07719 Tetratricopeptide repeat 365 395 3.9E-5 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 HL41_04205 5348f40c1a133e8f650417e213394239 413 Pfam PF14559 Tetratricopeptide repeat 274 327 1.3E-5 T 14-10-2018 HL41_04205 5348f40c1a133e8f650417e213394239 413 Pfam PF01435 Peptidase family M48 53 230 2.6E-38 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HL41_04205 5348f40c1a133e8f650417e213394239 413 Gene3D G3DSA:1.25.40.10 197 413 4.9E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_04205 5348f40c1a133e8f650417e213394239 413 Gene3D G3DSA:3.30.2010.10 48 130 2.2E-9 T 14-10-2018 HL41_04205 5348f40c1a133e8f650417e213394239 413 SMART SM00028 295 328 0.45 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_04205 5348f40c1a133e8f650417e213394239 413 SMART SM00028 363 396 8.7E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_04205 5348f40c1a133e8f650417e213394239 413 SMART SM00028 261 294 0.0053 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_04205 5348f40c1a133e8f650417e213394239 413 SMART SM00028 329 362 27.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_04205 5348f40c1a133e8f650417e213394239 413 SUPERFAMILY SSF48452 265 409 5.69E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_08780 281648f29b2fcfeeedb0eff9bbc93875 175 Gene3D G3DSA:3.30.700.10 20 149 1.7E-6 T 14-10-2018 HL41_08780 281648f29b2fcfeeedb0eff9bbc93875 175 SUPERFAMILY SSF54523 21 113 2.43E-10 T 14-10-2018 HL41_08780 281648f29b2fcfeeedb0eff9bbc93875 175 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 18 40 1.3E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_08780 281648f29b2fcfeeedb0eff9bbc93875 175 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 18 38 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 SUPERFAMILY SSF52096 32 367 1.82E-80 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 SMART SM00245 170 362 2.1E-72 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 Gene3D G3DSA:2.30.42.10 99 185 2.0E-97 T 14-10-2018 HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 Gene3D G3DSA:3.90.226.10 186 359 2.0E-97 T 14-10-2018 HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 53 377 7.1E-107 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 Gene3D G3DSA:3.30.750.44 40 337 2.0E-97 T 14-10-2018 HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 SMART SM00228 99 170 9.1E-18 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 Pfam PF13180 PDZ domain 100 172 2.7E-12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 SUPERFAMILY SSF50156 87 173 2.89E-19 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 HL41_04480 7e1af1356f0e6de51de8698c9a421349 412 Pfam PF03572 Peptidase family S41 197 361 2.0E-54 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HL41_05340 352f93a0627e805240db24b5f808354b 215 Gene3D G3DSA:3.40.50.300 1 215 1.8E-92 T 14-10-2018 HL41_05340 352f93a0627e805240db24b5f808354b 215 Pfam PF05191 Adenylate kinase, active site lid 127 162 5.5E-19 T 14-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 HL41_05340 352f93a0627e805240db24b5f808354b 215 PRINTS PR00094 Adenylate kinase signature 32 46 4.3E-37 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HL41_05340 352f93a0627e805240db24b5f808354b 215 PRINTS PR00094 Adenylate kinase signature 160 175 4.3E-37 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HL41_05340 352f93a0627e805240db24b5f808354b 215 PRINTS PR00094 Adenylate kinase signature 177 191 4.3E-37 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HL41_05340 352f93a0627e805240db24b5f808354b 215 PRINTS PR00094 Adenylate kinase signature 81 97 4.3E-37 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HL41_05340 352f93a0627e805240db24b5f808354b 215 PRINTS PR00094 Adenylate kinase signature 4 17 4.3E-37 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HL41_05340 352f93a0627e805240db24b5f808354b 215 SUPERFAMILY SSF52540 1 215 6.86E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05340 352f93a0627e805240db24b5f808354b 215 Pfam PF00406 Adenylate kinase 6 190 2.3E-61 T 14-10-2018 HL41_05340 352f93a0627e805240db24b5f808354b 215 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.5E-86 T 14-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 HL41_05340 352f93a0627e805240db24b5f808354b 215 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HL41_05340 352f93a0627e805240db24b5f808354b 215 Hamap MF_00235 Adenylate kinase [adk]. 1 213 56.151 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 SUPERFAMILY SSF109998 40 183 1.18E-21 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 Gene3D G3DSA:1.10.4030.30 450 491 6.6E-6 T 14-10-2018 HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 Gene3D G3DSA:3.10.50.40 409 449 6.6E-6 T 14-10-2018 HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 Gene3D G3DSA:3.10.50.40 259 343 2.7E-11 T 14-10-2018 HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 Pfam PF13624 SurA N-terminal domain 1 160 3.5E-44 T 14-10-2018 HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 Gene3D G3DSA:1.10.4030.30 237 376 2.7E-11 T 14-10-2018 HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 Pfam PF13145 PPIC-type PPIASE domain 366 459 9.1E-8 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 Pfam PF13145 PPIC-type PPIASE domain 241 353 3.3E-13 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 Gene3D G3DSA:1.10.4030.30 39 233 1.0E-13 T 14-10-2018 HL41_03110 40bdb0d9d88b48cbcf1b0a4852313222 602 SUPERFAMILY SSF54534 273 342 6.54E-6 T 14-10-2018 HL41_06560 3c7b4f662e708ac791fcd013afc357fb 151 Pfam PF00436 Single-strand binding protein family 3 105 8.8E-39 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 HL41_06560 3c7b4f662e708ac791fcd013afc357fb 151 Hamap MF_00984 Single-stranded DNA-binding protein. 3 109 33.636 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HL41_06560 3c7b4f662e708ac791fcd013afc357fb 151 SUPERFAMILY SSF50249 1 151 6.17E-49 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_06560 3c7b4f662e708ac791fcd013afc357fb 151 PIRSF PIRSF002070 1 147 1.0E-39 T 14-10-2018 HL41_06560 3c7b4f662e708ac791fcd013afc357fb 151 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 124 7.7E-46 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HL41_06560 3c7b4f662e708ac791fcd013afc357fb 151 Gene3D G3DSA:2.40.50.140 1 123 5.1E-44 T 14-10-2018 HL41_01630 527b75ab5dd867440aab1d54f5a3e684 540 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 162 173 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_01630 527b75ab5dd867440aab1d54f5a3e684 540 SUPERFAMILY SSF46548 61 192 1.4E-16 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_01630 527b75ab5dd867440aab1d54f5a3e684 540 Pfam PF02754 Cysteine-rich domain 398 457 7.0E-5 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_01630 527b75ab5dd867440aab1d54f5a3e684 540 Pfam PF13183 4Fe-4S dicluster domain 91 176 4.6E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_01620 ecfb8509cc1b72b575b339569e54caa2 185 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 5 107 1.3E-8 T 14-10-2018 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain HL41_08655 4cc6b0a15a930ebb506bb22973755e87 168 SUPERFAMILY SSF54862 4 150 1.78E-50 T 14-10-2018 HL41_08655 4cc6b0a15a930ebb506bb22973755e87 168 Gene3D G3DSA:3.30.70.20 5 155 1.8E-42 T 14-10-2018 HL41_08655 4cc6b0a15a930ebb506bb22973755e87 168 Pfam PF13247 4Fe-4S dicluster domain 55 144 1.5E-25 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_08655 4cc6b0a15a930ebb506bb22973755e87 168 Gene3D G3DSA:3.30.70.20 65 118 1.8E-42 T 14-10-2018 HL41_08655 4cc6b0a15a930ebb506bb22973755e87 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 92 103 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07355 848d22ea9d869c8bb375479efb6ccbf0 141 Gene3D G3DSA:3.30.70.20 76 141 2.1E-11 T 14-10-2018 HL41_07355 848d22ea9d869c8bb375479efb6ccbf0 141 Pfam PF13237 4Fe-4S dicluster domain 12 64 8.0E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_07355 848d22ea9d869c8bb375479efb6ccbf0 141 Pfam PF00037 4Fe-4S binding domain 77 99 4.4E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_07355 848d22ea9d869c8bb375479efb6ccbf0 141 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07355 848d22ea9d869c8bb375479efb6ccbf0 141 Gene3D G3DSA:3.30.70.20 2 75 6.2E-8 T 14-10-2018 HL41_07355 848d22ea9d869c8bb375479efb6ccbf0 141 SUPERFAMILY SSF54862 8 137 2.88E-34 T 14-10-2018 HL41_00560 da2eb961cb0d37045f1465c5893c014a 435 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 144 353 6.2E-73 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_00560 da2eb961cb0d37045f1465c5893c014a 435 SUPERFAMILY SSF52540 92 359 9.12E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00560 da2eb961cb0d37045f1465c5893c014a 435 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 344 353 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_00560 da2eb961cb0d37045f1465c5893c014a 435 SMART SM00382 156 337 2.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_00560 da2eb961cb0d37045f1465c5893c014a 435 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 9 433 2.6E-175 T 14-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_00560 da2eb961cb0d37045f1465c5893c014a 435 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 88 1.2E-6 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 HL41_00560 da2eb961cb0d37045f1465c5893c014a 435 Gene3D G3DSA:3.40.50.12240 15 435 1.1E-153 T 14-10-2018 HL41_04080 42f41a069e350f0049bbc8565b2e6549 215 Gene3D G3DSA:3.30.300.20 65 150 1.2E-7 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta HL41_04080 42f41a069e350f0049bbc8565b2e6549 215 Gene3D G3DSA:3.30.1370.50 151 215 4.0E-5 T 14-10-2018 IPR036867 R3H domain superfamily GO:0003676 HL41_04080 42f41a069e350f0049bbc8565b2e6549 215 SMART SM01245 6 58 2.6E-5 T 14-10-2018 IPR032782 Jag, N-terminal HL41_04080 42f41a069e350f0049bbc8565b2e6549 215 Gene3D G3DSA:3.30.30.80 4 58 4.5E-8 T 14-10-2018 IPR038247 Jag, N-terminal domain superfamily HL41_04080 42f41a069e350f0049bbc8565b2e6549 215 Pfam PF14804 Jag N-terminus 8 56 4.0E-10 T 14-10-2018 IPR032782 Jag, N-terminal HL41_06080 17811e4e539c89fef3a86e9385b5c807 226 Gene3D G3DSA:2.30.30.910 94 220 1.2E-24 T 14-10-2018 HL41_06080 17811e4e539c89fef3a86e9385b5c807 226 Pfam PF03963 Flagellar hook capping protein - N-terminal region 8 80 1.1E-17 T 14-10-2018 IPR005648 Flagellar hook capping protein HL41_06080 17811e4e539c89fef3a86e9385b5c807 226 Pfam PF13860 FlgD Ig-like domain 119 177 3.0E-17 T 14-10-2018 IPR025965 FlgD Ig-like domain HL41_06080 17811e4e539c89fef3a86e9385b5c807 226 Gene3D G3DSA:2.60.40.4070 105 191 1.2E-24 T 14-10-2018 HL41_00530 0fc700a7f7bb00b5a4749304a288c7f2 132 Pfam PF00460 Flagella basal body rod protein 15 39 2.0E-6 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HL41_00530 0fc700a7f7bb00b5a4749304a288c7f2 132 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site HL41_00530 0fc700a7f7bb00b5a4749304a288c7f2 132 PIRSF PIRSF002889 1 130 1.1E-29 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 HL41_00530 0fc700a7f7bb00b5a4749304a288c7f2 132 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 5 127 4.4E-27 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 HL41_04200 42eaf83eb25d200ff071c9636e1ee17c 145 SUPERFAMILY SSF56276 8 123 1.14E-23 T 14-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 HL41_04200 42eaf83eb25d200ff071c9636e1ee17c 145 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 8 122 9.3E-23 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HL41_04200 42eaf83eb25d200ff071c9636e1ee17c 145 Gene3D G3DSA:3.60.90.10 6 137 1.2E-35 T 14-10-2018 HL41_04200 42eaf83eb25d200ff071c9636e1ee17c 145 Pfam PF02675 S-adenosylmethionine decarboxylase 11 122 9.6E-26 T 14-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 SUPERFAMILY SSF50447 791 885 5.41E-33 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Gene3D G3DSA:2.40.30.10 560 678 2.1E-44 T 14-10-2018 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 SUPERFAMILY SSF52156 667 795 2.62E-39 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 886 17.763 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 390 547 8.1E-34 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Pfam PF00009 Elongation factor Tu GTP binding domain 392 548 1.4E-34 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Gene3D G3DSA:2.40.30.10 790 887 3.7E-33 T 14-10-2018 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 SUPERFAMILY SSF52540 382 557 4.57E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 313 362 3.8E-15 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 53 8.8E-12 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal HL41_03145 bebcaa2b14bcf38064d055264321c629 888 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 305 886 3.3E-261 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Gene3D G3DSA:1.10.10.2480 1 72 1.4E-9 T 14-10-2018 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Gene3D G3DSA:3.40.50.10050 682 789 9.5E-41 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily HL41_03145 bebcaa2b14bcf38064d055264321c629 888 ProSitePatterns PS01176 Initiation factor 2 signature. 839 861 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Pfam PF11987 Translation-initiation factor 2 673 778 1.4E-39 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 Gene3D G3DSA:3.40.50.300 384 559 6.2E-72 T 14-10-2018 HL41_03145 bebcaa2b14bcf38064d055264321c629 888 SUPERFAMILY SSF50447 561 643 8.39E-28 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_07405 fe326203d8d5318bfd27c36186b237de 276 Gene3D G3DSA:3.40.190.10 76 179 9.1E-58 T 14-10-2018 HL41_07405 fe326203d8d5318bfd27c36186b237de 276 SUPERFAMILY SSF53850 4 264 1.5E-55 T 14-10-2018 HL41_07405 fe326203d8d5318bfd27c36186b237de 276 Pfam PF02621 Menaquinone biosynthesis 4 259 2.6E-47 T 14-10-2018 IPR003773 Menaquinone biosynthesis enzyme HL41_07405 fe326203d8d5318bfd27c36186b237de 276 Gene3D G3DSA:3.40.190.10 6 250 9.1E-58 T 14-10-2018 HL41_07405 fe326203d8d5318bfd27c36186b237de 276 Hamap MF_00995 Chorismate dehydratase [mqnA]. 5 264 22.743 T 14-10-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 HL41_01730 2cdef239ea77fba49492e241c730f864 394 Gene3D G3DSA:3.90.1150.10 15 374 3.3E-125 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_01730 2cdef239ea77fba49492e241c730f864 394 Gene3D G3DSA:3.40.640.10 68 298 3.3E-125 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_01730 2cdef239ea77fba49492e241c730f864 394 SUPERFAMILY SSF53383 14 387 2.31E-85 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_01730 2cdef239ea77fba49492e241c730f864 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 240 253 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 HL41_01730 2cdef239ea77fba49492e241c730f864 394 Pfam PF00155 Aminotransferase class I and II 34 378 3.8E-54 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HL41_01120 bc90d3c599c14cc2ddc3b3564028e3d8 146 SUPERFAMILY SSF69819 4 146 1.7E-33 T 14-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 HL41_01120 bc90d3c599c14cc2ddc3b3564028e3d8 146 Gene3D G3DSA:3.55.10.10 3 146 5.7E-35 T 14-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 HL41_01120 bc90d3c599c14cc2ddc3b3564028e3d8 146 Pfam PF01951 Archease protein family (MTH1598/TM1083) 6 146 1.2E-31 T 14-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 HL41_01120 bc90d3c599c14cc2ddc3b3564028e3d8 146 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 10 133 3.0E-18 T 14-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 HL41_06740 23421f65a270c7b1cc53dba7f7f90da6 433 Gene3D G3DSA:3.40.50.2000 1 254 1.7E-41 T 14-10-2018 HL41_06740 23421f65a270c7b1cc53dba7f7f90da6 433 Pfam PF00534 Glycosyl transferases group 1 247 408 3.0E-32 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 HL41_06740 23421f65a270c7b1cc53dba7f7f90da6 433 SUPERFAMILY SSF53756 1 431 3.84E-84 T 14-10-2018 HL41_06740 23421f65a270c7b1cc53dba7f7f90da6 433 Gene3D G3DSA:3.40.50.2000 255 413 7.2E-37 T 14-10-2018 HL41_06740 23421f65a270c7b1cc53dba7f7f90da6 433 Pfam PF08323 Starch synthase catalytic domain 2 227 1.3E-21 T 14-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HL41_00315 3f48f0199573b1758bc3fe3fed91aaf9 364 SUPERFAMILY SSF103263 4 350 7.59E-140 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HL41_00315 3f48f0199573b1758bc3fe3fed91aaf9 364 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HL41_00315 3f48f0199573b1758bc3fe3fed91aaf9 364 ProSitePatterns PS00788 Chorismate synthase signature 2. 125 141 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HL41_00315 3f48f0199573b1758bc3fe3fed91aaf9 364 Pfam PF01264 Chorismate synthase 10 345 4.2E-141 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HL41_00315 3f48f0199573b1758bc3fe3fed91aaf9 364 Gene3D G3DSA:3.60.150.10 1 358 2.7E-153 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HL41_00315 3f48f0199573b1758bc3fe3fed91aaf9 364 TIGRFAM TIGR00033 aroC: chorismate synthase 10 348 8.4E-133 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HL41_00315 3f48f0199573b1758bc3fe3fed91aaf9 364 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HL41_00315 3f48f0199573b1758bc3fe3fed91aaf9 364 PIRSF PIRSF001456 3 358 7.0E-146 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HL41_00315 3f48f0199573b1758bc3fe3fed91aaf9 364 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 38.257 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HL41_05550 64c923b3dd413083d264555fa57ea3f9 175 Pfam PF00881 Nitroreductase family 71 154 2.3E-16 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HL41_05550 64c923b3dd413083d264555fa57ea3f9 175 Pfam PF00881 Nitroreductase family 15 69 3.7E-14 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HL41_05550 64c923b3dd413083d264555fa57ea3f9 175 Gene3D G3DSA:3.40.109.10 5 175 2.5E-54 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HL41_05550 64c923b3dd413083d264555fa57ea3f9 175 SUPERFAMILY SSF55469 10 172 2.62E-52 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HL41_01705 c83ac06e2fb4bdd2ed80c310629a3930 152 Gene3D G3DSA:2.30.30.830 77 150 4.7E-8 T 14-10-2018 HL41_01705 c83ac06e2fb4bdd2ed80c310629a3930 152 Pfam PF04351 Pilus assembly protein, PilP 81 149 1.5E-8 T 14-10-2018 IPR007446 Pilus assembly protein PilP HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 SUPERFAMILY SSF52096 11 193 3.8E-75 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 Pfam PF00574 Clp protease 14 193 1.4E-88 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 4 194 44.758 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 113 126 - T 14-10-2018 IPR033135 ClpP, histidine active site HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 4 193 1.2E-102 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 91 102 - T 14-10-2018 IPR018215 ClpP, Ser active site HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 Gene3D G3DSA:3.90.226.10 1 195 1.4E-86 T 14-10-2018 HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 PRINTS PR00127 Clp protease catalytic subunit P signature 169 188 9.0E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 PRINTS PR00127 Clp protease catalytic subunit P signature 20 35 9.0E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 PRINTS PR00127 Clp protease catalytic subunit P signature 91 108 9.0E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 PRINTS PR00127 Clp protease catalytic subunit P signature 60 80 9.0E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_05285 6f0ecd2d0388ec9184d104cbdb0118f3 196 PRINTS PR00127 Clp protease catalytic subunit P signature 112 131 9.0E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HL41_01650 9e88baa788585fee15fa725c188331a7 465 Gene3D G3DSA:3.40.50.880 249 460 2.6E-12 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_01650 9e88baa788585fee15fa725c188331a7 465 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 12 457 4.2E-122 T 14-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 HL41_01650 9e88baa788585fee15fa725c188331a7 465 SUPERFAMILY SSF52540 9 192 1.06E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_01650 9e88baa788585fee15fa725c188331a7 465 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 11 188 5.2E-14 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HL41_01650 9e88baa788585fee15fa725c188331a7 465 SUPERFAMILY SSF52317 248 454 7.4E-33 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_01650 9e88baa788585fee15fa725c188331a7 465 Gene3D G3DSA:3.40.50.300 9 196 1.5E-24 T 14-10-2018 HL41_01650 9e88baa788585fee15fa725c188331a7 465 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 252 444 1.7E-33 T 14-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 HL41_06160 1a4ae3b5ca63e7f57261b1170d241cbf 253 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 243 9.5E-59 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06160 1a4ae3b5ca63e7f57261b1170d241cbf 253 Pfam PF00121 Triosephosphate isomerase 5 249 1.8E-94 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06160 1a4ae3b5ca63e7f57261b1170d241cbf 253 Gene3D G3DSA:3.20.20.70 1 252 4.2E-103 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_06160 1a4ae3b5ca63e7f57261b1170d241cbf 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 251 59.456 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06160 1a4ae3b5ca63e7f57261b1170d241cbf 253 ProSitePatterns PS00171 Triosephosphate isomerase active site. 167 177 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06160 1a4ae3b5ca63e7f57261b1170d241cbf 253 SUPERFAMILY SSF51351 1 251 9.56E-95 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_05145 a233483e3ab9f1eabc4f34d5f8f0d542 79 Pfam PF01455 HupF/HypC family 1 67 5.4E-26 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HL41_05145 a233483e3ab9f1eabc4f34d5f8f0d542 79 SUPERFAMILY SSF159127 1 75 9.55E-25 T 14-10-2018 IPR037254 HupF/HypC superfamily HL41_05145 a233483e3ab9f1eabc4f34d5f8f0d542 79 Gene3D G3DSA:2.40.50.970 1 76 3.0E-27 T 14-10-2018 IPR037254 HupF/HypC superfamily HL41_05145 a233483e3ab9f1eabc4f34d5f8f0d542 79 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 40 56 2.9E-12 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HL41_05145 a233483e3ab9f1eabc4f34d5f8f0d542 79 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 2.9E-12 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HL41_05145 a233483e3ab9f1eabc4f34d5f8f0d542 79 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 18 34 2.9E-12 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HL41_05145 a233483e3ab9f1eabc4f34d5f8f0d542 79 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 58 70 2.9E-12 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HL41_05145 a233483e3ab9f1eabc4f34d5f8f0d542 79 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 73 3.8E-23 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HL41_01030 2960f84aec23c5d6fb0506ff13dd95ae 253 SUPERFAMILY SSF56281 1 253 5.28E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_01030 2960f84aec23c5d6fb0506ff13dd95ae 253 Gene3D G3DSA:3.60.15.10 1 252 1.0E-68 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_01030 2960f84aec23c5d6fb0506ff13dd95ae 253 Pfam PF12706 Beta-lactamase superfamily domain 46 221 4.5E-19 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_01030 2960f84aec23c5d6fb0506ff13dd95ae 253 SMART SM00849 18 220 5.0E-6 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_08405 2b16f54a756839dbfe426c7e3e356b46 274 Gene3D G3DSA:1.20.1440.230 166 262 2.7E-16 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08405 2b16f54a756839dbfe426c7e3e356b46 274 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 9 131 6.2E-51 T 14-10-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 HL41_08405 2b16f54a756839dbfe426c7e3e356b46 274 SMART SM00928 168 215 4.4E-8 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08405 2b16f54a756839dbfe426c7e3e356b46 274 SUPERFAMILY SSF140490 165 256 1.14E-17 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08405 2b16f54a756839dbfe426c7e3e356b46 274 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 170 252 2.2E-16 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 Pfam PF00224 Pyruvate kinase, barrel domain 1 340 8.6E-120 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 Gene3D G3DSA:3.20.20.60 2 335 5.2E-169 T 14-10-2018 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 466 4.7E-160 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 SUPERFAMILY SSF51621 1 343 1.61E-95 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 Gene3D G3DSA:3.40.1380.20 336 465 5.2E-169 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 PRINTS PR01050 Pyruvate kinase family signature 313 329 3.2E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 PRINTS PR01050 Pyruvate kinase family signature 269 293 3.2E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 PRINTS PR01050 Pyruvate kinase family signature 244 268 3.2E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 PRINTS PR01050 Pyruvate kinase family signature 217 243 3.2E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 PRINTS PR01050 Pyruvate kinase family signature 187 201 3.2E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 PRINTS PR01050 Pyruvate kinase family signature 59 75 3.2E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 PRINTS PR01050 Pyruvate kinase family signature 294 312 3.2E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 Gene3D G3DSA:2.40.33.10 70 169 5.2E-169 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 354 467 1.0E-27 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 SUPERFAMILY SSF50800 70 168 3.31E-20 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily HL41_02420 26ff99888121ff0c64e7d98af3659b07 478 SUPERFAMILY SSF52935 323 467 2.09E-34 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HL41_06800 d299f45c6ae93f9b6e3cf6c13fa801f8 315 Gene3D G3DSA:3.20.20.300 1 313 5.7E-63 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 HL41_06800 d299f45c6ae93f9b6e3cf6c13fa801f8 315 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 5 278 1.1E-37 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HL41_06800 d299f45c6ae93f9b6e3cf6c13fa801f8 315 SUPERFAMILY SSF51445 14 310 1.05E-43 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily HL41_05810 dc6758e3a2d699336ccb99fb50aac2d7 437 SUPERFAMILY SSF48695 54 407 1.05E-29 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_00475 35d3380799a0946633f830216314de43 185 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 178 3.9E-35 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal HL41_00475 35d3380799a0946633f830216314de43 185 SUPERFAMILY SSF53639 3 180 6.87E-41 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily HL41_00475 35d3380799a0946633f830216314de43 185 SMART SM01007 7 180 4.7E-35 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal HL41_00475 35d3380799a0946633f830216314de43 185 Gene3D G3DSA:3.40.225.10 1 185 2.4E-46 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily HL41_07315 8e086eb8464c5a248027faa626587e31 697 Gene3D G3DSA:3.30.470.20 487 694 2.1E-80 T 14-10-2018 HL41_07315 8e086eb8464c5a248027faa626587e31 697 SUPERFAMILY SSF52210 131 287 8.37E-47 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HL41_07315 8e086eb8464c5a248027faa626587e31 697 Gene3D G3DSA:3.40.50.720 1 129 1.5E-49 T 14-10-2018 HL41_07315 8e086eb8464c5a248027faa626587e31 697 Gene3D G3DSA:3.40.50.261 130 290 1.6E-64 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HL41_07315 8e086eb8464c5a248027faa626587e31 697 SUPERFAMILY SSF51735 2 139 1.61E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_07315 8e086eb8464c5a248027faa626587e31 697 SUPERFAMILY SSF52210 294 446 4.71E-32 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HL41_07315 8e086eb8464c5a248027faa626587e31 697 Gene3D G3DSA:3.40.50.261 293 456 2.1E-49 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 HL41_07315 8e086eb8464c5a248027faa626587e31 697 Pfam PF13380 CoA binding domain 10 135 4.5E-28 T 14-10-2018 IPR003781 CoA-binding GO:0048037 HL41_07315 8e086eb8464c5a248027faa626587e31 697 SUPERFAMILY SSF56059 485 696 3.36E-43 T 14-10-2018 HL41_07315 8e086eb8464c5a248027faa626587e31 697 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 2 446 1.1E-183 T 14-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 HL41_07315 8e086eb8464c5a248027faa626587e31 697 SMART SM00881 5 100 7.4E-39 T 14-10-2018 IPR003781 CoA-binding GO:0048037 HL41_07315 8e086eb8464c5a248027faa626587e31 697 Gene3D G3DSA:3.30.1490.20 503 580 2.1E-80 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 HL41_07315 8e086eb8464c5a248027faa626587e31 697 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 151 288 1.7E-56 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HL41_07315 8e086eb8464c5a248027faa626587e31 697 Pfam PF13549 ATP-grasp domain 479 696 5.2E-76 T 14-10-2018 HL41_02125 507a2d05e75c3f6011f7bec1aecfc94c 240 Pfam PF14532 Sigma-54 interaction domain 34 138 1.3E-10 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_02125 507a2d05e75c3f6011f7bec1aecfc94c 240 SUPERFAMILY SSF52540 33 221 2.5E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02125 507a2d05e75c3f6011f7bec1aecfc94c 240 Gene3D G3DSA:1.10.8.60 158 222 2.8E-20 T 14-10-2018 HL41_02125 507a2d05e75c3f6011f7bec1aecfc94c 240 Gene3D G3DSA:3.40.50.300 27 157 3.3E-16 T 14-10-2018 HL41_07515 0b41f405c73483621a524a0629fc23ca 218 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HL41_07515 0b41f405c73483621a524a0629fc23ca 218 Gene3D G3DSA:3.20.20.70 1 216 2.3E-85 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_07515 0b41f405c73483621a524a0629fc23ca 218 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 200 9.8E-88 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HL41_07515 0b41f405c73483621a524a0629fc23ca 218 PIRSF PIRSF001461 1 218 2.2E-96 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HL41_07515 0b41f405c73483621a524a0629fc23ca 218 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 1.6E-93 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HL41_07515 0b41f405c73483621a524a0629fc23ca 218 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HL41_07515 0b41f405c73483621a524a0629fc23ca 218 SUPERFAMILY SSF51366 1 215 2.71E-74 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HL41_08845 5d197718adb9db42542695571d07a2b5 114 Pfam PF01250 Ribosomal protein S6 13 100 3.2E-25 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08845 5d197718adb9db42542695571d07a2b5 114 SUPERFAMILY SSF54995 11 106 1.7E-27 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08845 5d197718adb9db42542695571d07a2b5 114 Gene3D G3DSA:3.30.70.60 5 110 6.4E-29 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 HL41_08845 5d197718adb9db42542695571d07a2b5 114 TIGRFAM TIGR00166 S6: ribosomal protein bS6 11 102 4.9E-23 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08845 5d197718adb9db42542695571d07a2b5 114 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 10 103 19.024 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 SUPERFAMILY SSF55874 550 691 5.89E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 SMART SM00304 305 360 2.9E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 SUPERFAMILY SSF47384 469 546 1.41E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 Gene3D G3DSA:3.30.565.10 544 692 2.4E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 PIRSF PIRSF037532 5 697 4.1E-95 T 14-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 Pfam PF00672 HAMP domain 305 355 4.6E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 SMART SM00387 589 694 2.1E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 Pfam PF00512 His Kinase A (phospho-acceptor) domain 486 539 2.0E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 SUPERFAMILY SSF158472 305 358 4.18E-6 T 14-10-2018 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 SMART SM00388 478 550 0.0026 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 654 672 9.8E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 678 691 9.8E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 626 640 9.8E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 Gene3D G3DSA:1.20.1480.50 268 365 1.4E-7 T 14-10-2018 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 Gene3D G3DSA:1.10.287.130 463 543 4.5E-9 T 14-10-2018 HL41_00200 247ff5d3dafeedc8392c28ed747395f8 700 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 592 692 2.2E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_05530 5aa43a7004fcca3018c71a6f57743222 253 Gene3D G3DSA:3.40.30.10 95 251 2.1E-24 T 14-10-2018 HL41_05530 5aa43a7004fcca3018c71a6f57743222 253 Pfam PF10411 Disulfide bond isomerase protein N-terminus 36 93 2.8E-16 T 14-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal HL41_05530 5aa43a7004fcca3018c71a6f57743222 253 Pfam PF13098 Thioredoxin-like domain 128 239 3.7E-14 T 14-10-2018 IPR012336 Thioredoxin-like fold HL41_05530 5aa43a7004fcca3018c71a6f57743222 253 Gene3D G3DSA:3.10.450.70 31 94 2.8E-9 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 HL41_05530 5aa43a7004fcca3018c71a6f57743222 253 SUPERFAMILY SSF52833 120 249 9.65E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily HL41_05530 5aa43a7004fcca3018c71a6f57743222 253 SUPERFAMILY SSF54423 36 96 9.81E-9 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 HL41_05555 5aa43a7004fcca3018c71a6f57743222 253 Gene3D G3DSA:3.40.30.10 95 251 2.1E-24 T 14-10-2018 HL41_05555 5aa43a7004fcca3018c71a6f57743222 253 Pfam PF10411 Disulfide bond isomerase protein N-terminus 36 93 2.8E-16 T 14-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal HL41_05555 5aa43a7004fcca3018c71a6f57743222 253 Pfam PF13098 Thioredoxin-like domain 128 239 3.7E-14 T 14-10-2018 IPR012336 Thioredoxin-like fold HL41_05555 5aa43a7004fcca3018c71a6f57743222 253 Gene3D G3DSA:3.10.450.70 31 94 2.8E-9 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 HL41_05555 5aa43a7004fcca3018c71a6f57743222 253 SUPERFAMILY SSF52833 120 249 9.65E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily HL41_05555 5aa43a7004fcca3018c71a6f57743222 253 SUPERFAMILY SSF54423 36 96 9.81E-9 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 HL41_07690 bf19ac7cc4ca73b877d3c7d0c059246f 306 Pfam PF02685 Glucokinase 2 304 2.1E-62 T 14-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 HL41_07690 bf19ac7cc4ca73b877d3c7d0c059246f 306 Gene3D G3DSA:3.40.367.20 96 289 1.0E-71 T 14-10-2018 HL41_07690 bf19ac7cc4ca73b877d3c7d0c059246f 306 Gene3D G3DSA:3.30.420.40 1 299 1.0E-71 T 14-10-2018 HL41_07690 bf19ac7cc4ca73b877d3c7d0c059246f 306 SUPERFAMILY SSF53067 2 304 1.61E-39 T 14-10-2018 HL41_04230 09db93650b33d56314c6964284a62c7b 767 SMART SM00534 324 508 1.2E-58 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HL41_04230 09db93650b33d56314c6964284a62c7b 767 SMART SM00463 686 764 6.1E-13 T 14-10-2018 IPR002625 Smr domain HL41_04230 09db93650b33d56314c6964284a62c7b 767 SUPERFAMILY SSF160443 691 763 1.83E-7 T 14-10-2018 IPR036063 Smr domain superfamily HL41_04230 09db93650b33d56314c6964284a62c7b 767 SMART SM00533 7 307 0.0013 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HL41_04230 09db93650b33d56314c6964284a62c7b 767 Pfam PF00488 MutS domain V 328 508 8.6E-37 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HL41_04230 09db93650b33d56314c6964284a62c7b 767 SUPERFAMILY SSF52540 285 511 7.53E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04230 09db93650b33d56314c6964284a62c7b 767 Pfam PF01713 Smr domain 691 763 1.5E-16 T 14-10-2018 IPR002625 Smr domain HL41_04230 09db93650b33d56314c6964284a62c7b 767 Gene3D G3DSA:3.40.50.300 286 588 6.5E-71 T 14-10-2018 HL41_04230 09db93650b33d56314c6964284a62c7b 767 Gene3D G3DSA:3.30.1370.110 678 764 1.5E-20 T 14-10-2018 HL41_04230 09db93650b33d56314c6964284a62c7b 767 SUPERFAMILY SSF48334 82 258 3.66E-11 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily HL41_04230 09db93650b33d56314c6964284a62c7b 767 PIRSF PIRSF005814 1 764 2.2E-173 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HL41_04230 09db93650b33d56314c6964284a62c7b 767 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 1 763 16.761 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HL41_07730 f5e8acadd94491900f3dfd9912dde39b 319 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 7 260 7.5E-38 T 14-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR HL41_07730 f5e8acadd94491900f3dfd9912dde39b 319 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 9 279 7.2E-54 T 14-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR HL41_00775 98ad47844cf4320b70e42f9871488aab 332 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 243 332 5.3E-37 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HL41_00775 98ad47844cf4320b70e42f9871488aab 332 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 111 191 4.0E-27 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HL41_00775 98ad47844cf4320b70e42f9871488aab 332 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 6 332 68.183 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HL41_00775 98ad47844cf4320b70e42f9871488aab 332 Gene3D G3DSA:3.40.47.10 4 332 7.1E-130 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 HL41_00775 98ad47844cf4320b70e42f9871488aab 332 SUPERFAMILY SSF53901 10 332 8.51E-66 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 HL41_00775 98ad47844cf4320b70e42f9871488aab 332 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 7 332 5.7E-120 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HL41_04755 6caa3136a42aad8ce2682aefc924dcb3 206 SUPERFAMILY SSF51366 5 204 2.2E-52 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HL41_04755 6caa3136a42aad8ce2682aefc924dcb3 206 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 5 206 35.127 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 HL41_04755 6caa3136a42aad8ce2682aefc924dcb3 206 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 7 202 6.4E-38 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 HL41_04755 6caa3136a42aad8ce2682aefc924dcb3 206 Gene3D G3DSA:3.20.20.70 4 206 2.3E-61 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_04435 89cb5e06166984d834e7ff2f6e1824cd 339 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 70 313 6.6E-54 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 HL41_04435 89cb5e06166984d834e7ff2f6e1824cd 339 Gene3D G3DSA:3.40.50.2000 1 151 2.3E-41 T 14-10-2018 HL41_04435 89cb5e06166984d834e7ff2f6e1824cd 339 SUPERFAMILY SSF53756 1 336 2.2E-85 T 14-10-2018 HL41_04435 89cb5e06166984d834e7ff2f6e1824cd 339 Gene3D G3DSA:3.40.50.2000 170 337 2.6E-47 T 14-10-2018 HL41_00605 66fe71c5dd6664666283171392510707 466 Pfam PF14698 Argininosuccinate lyase C-terminal 368 435 1.4E-23 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HL41_00605 66fe71c5dd6664666283171392510707 466 Gene3D G3DSA:1.10.40.30 365 437 2.8E-174 T 14-10-2018 HL41_00605 66fe71c5dd6664666283171392510707 466 Pfam PF00206 Lyase 11 303 1.8E-74 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal HL41_00605 66fe71c5dd6664666283171392510707 466 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 HL41_00605 66fe71c5dd6664666283171392510707 466 TIGRFAM TIGR00838 argH: argininosuccinate lyase 9 460 7.5E-177 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00145 Argininosuccinate lyase family signature 236 260 2.6E-57 T 14-10-2018 HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00145 Argininosuccinate lyase family signature 106 128 2.6E-57 T 14-10-2018 HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00145 Argininosuccinate lyase family signature 280 296 2.6E-57 T 14-10-2018 HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00145 Argininosuccinate lyase family signature 315 334 2.6E-57 T 14-10-2018 HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00145 Argininosuccinate lyase family signature 198 214 2.6E-57 T 14-10-2018 HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00145 Argininosuccinate lyase family signature 147 167 2.6E-57 T 14-10-2018 HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00149 Fumarate lyase superfamily signature 152 170 1.6E-24 T 14-10-2018 IPR000362 Fumarate lyase family HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00149 Fumarate lyase superfamily signature 107 125 1.6E-24 T 14-10-2018 IPR000362 Fumarate lyase family HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00149 Fumarate lyase superfamily signature 236 263 1.6E-24 T 14-10-2018 IPR000362 Fumarate lyase family HL41_00605 66fe71c5dd6664666283171392510707 466 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 1.6E-24 T 14-10-2018 IPR000362 Fumarate lyase family HL41_00605 66fe71c5dd6664666283171392510707 466 Hamap MF_00006 Argininosuccinate lyase [argH]. 7 458 38.896 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HL41_00605 66fe71c5dd6664666283171392510707 466 Gene3D G3DSA:1.20.200.10 124 453 2.8E-174 T 14-10-2018 HL41_00605 66fe71c5dd6664666283171392510707 466 SUPERFAMILY SSF48557 9 460 6.28E-136 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 HL41_00605 66fe71c5dd6664666283171392510707 466 Gene3D G3DSA:1.10.275.10 30 234 2.8E-174 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal HL41_06320 7949a213f80ebbbd8f0963251ecffa52 146 Gene3D G3DSA:3.40.50.150 1 129 1.2E-17 T 14-10-2018 HL41_06320 7949a213f80ebbbd8f0963251ecffa52 146 SUPERFAMILY SSF53335 19 138 1.04E-18 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_06320 7949a213f80ebbbd8f0963251ecffa52 146 Pfam PF13489 Methyltransferase domain 22 113 1.7E-13 T 14-10-2018 HL41_08785 26a803b82df7ce955462d3b131b65960 135 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 26 0.0013 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_08785 26a803b82df7ce955462d3b131b65960 135 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 27 4.8E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 SUPERFAMILY SSF48150 3 210 5.5E-72 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 Gene3D G3DSA:1.10.340.30 22 133 1.0E-80 T 14-10-2018 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 TIGRFAM TIGR01083 nth: endonuclease III 4 196 1.4E-79 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 SMART SM00525 188 208 7.5E-7 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 1.0E-30 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 Gene3D G3DSA:1.10.1670.10 12 205 1.0E-80 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 1.3E-6 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 Hamap MF_00942 Endonuclease III [nth]. 1 211 38.813 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 PIRSF PIRSF001435 1 212 6.0E-55 T 14-10-2018 HL41_04715 93fde47e0e60ef6cfe38f0dc10c611ca 212 SMART SM00478 39 187 3.7E-64 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HL41_03850 f85d3c8b94d604c1c61dd643e0fa8903 508 Gene3D G3DSA:3.30.300.30 405 505 1.4E-15 T 14-10-2018 HL41_03850 f85d3c8b94d604c1c61dd643e0fa8903 508 Gene3D G3DSA:3.40.50.12780 1 404 5.5E-94 T 14-10-2018 HL41_03850 f85d3c8b94d604c1c61dd643e0fa8903 508 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 490 1.6E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain HL41_03850 f85d3c8b94d604c1c61dd643e0fa8903 508 Pfam PF00501 AMP-binding enzyme 10 409 7.7E-86 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HL41_03850 f85d3c8b94d604c1c61dd643e0fa8903 508 SUPERFAMILY SSF56801 3 502 1.44E-116 T 14-10-2018 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 432 3.1E-153 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 Pfam PF00815 Histidinol dehydrogenase 29 433 2.1E-154 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 Gene3D G3DSA:3.40.50.1980 239 355 2.0E-115 T 14-10-2018 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 Gene3D G3DSA:3.40.50.1980 33 237 2.0E-115 T 14-10-2018 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 SUPERFAMILY SSF53720 29 433 7.45E-69 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 PRINTS PR00083 Histidinol dehydrogenase signature 206 231 1.9E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 1.9E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 PRINTS PR00083 Histidinol dehydrogenase signature 367 385 1.9E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 PRINTS PR00083 Histidinol dehydrogenase signature 257 276 1.9E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 PRINTS PR00083 Histidinol dehydrogenase signature 141 167 1.9E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 PRINTS PR00083 Histidinol dehydrogenase signature 326 351 1.9E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 PRINTS PR00083 Histidinol dehydrogenase signature 176 202 1.9E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 PRINTS PR00083 Histidinol dehydrogenase signature 235 256 1.9E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 235 267 - T 14-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 6 433 39.884 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_03660 fc175cafa660059ec6eab7349b83cca8 441 PIRSF PIRSF000099 3 436 2.7E-157 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HL41_02610 89cf1a3db0bb1c35f0ed04c05229a1f5 356 SUPERFAMILY SSF160544 244 351 9.16E-44 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HL41_02610 89cf1a3db0bb1c35f0ed04c05229a1f5 356 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 347 1.3E-117 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HL41_02610 89cf1a3db0bb1c35f0ed04c05229a1f5 356 Gene3D G3DSA:3.40.1690.10 218 356 4.3E-56 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HL41_02610 89cf1a3db0bb1c35f0ed04c05229a1f5 356 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 7 353 1.4E-119 T 14-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 HL41_02610 89cf1a3db0bb1c35f0ed04c05229a1f5 356 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 3.0E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HL41_02610 89cf1a3db0bb1c35f0ed04c05229a1f5 356 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 3.0E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HL41_02610 89cf1a3db0bb1c35f0ed04c05229a1f5 356 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 3.0E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HL41_02610 89cf1a3db0bb1c35f0ed04c05229a1f5 356 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 3.0E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HL41_02610 89cf1a3db0bb1c35f0ed04c05229a1f5 356 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 3.0E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HL41_01195 f20a67d692ade1f57441b05d46facd49 150 Gene3D G3DSA:3.40.630.30 1 133 1.4E-32 T 14-10-2018 HL41_01195 f20a67d692ade1f57441b05d46facd49 150 SUPERFAMILY SSF55729 1 127 3.04E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase HL41_01195 f20a67d692ade1f57441b05d46facd49 150 Pfam PF00583 Acetyltransferase (GNAT) family 40 115 2.1E-12 T 14-10-2018 IPR000182 GNAT domain HL41_03195 21511823c1047c3ef69139009b6d2394 225 Pfam PF00005 ABC transporter 21 170 2.1E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_03195 21511823c1047c3ef69139009b6d2394 225 SMART SM00382 30 219 6.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_03195 21511823c1047c3ef69139009b6d2394 225 SUPERFAMILY SSF52540 2 222 1.77E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03195 21511823c1047c3ef69139009b6d2394 225 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_03195 21511823c1047c3ef69139009b6d2394 225 Gene3D G3DSA:3.40.50.300 1 225 8.4E-66 T 14-10-2018 HL41_08320 a7012e5000b524d2e897cb7f10f0d0f6 253 Gene3D G3DSA:3.40.50.300 3 249 3.0E-71 T 14-10-2018 HL41_08320 a7012e5000b524d2e897cb7f10f0d0f6 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_08320 a7012e5000b524d2e897cb7f10f0d0f6 253 SMART SM00382 32 225 8.9E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_08320 a7012e5000b524d2e897cb7f10f0d0f6 253 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 8 253 1.1E-123 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 HL41_08320 a7012e5000b524d2e897cb7f10f0d0f6 253 SUPERFAMILY SSF52540 7 240 4.96E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08320 a7012e5000b524d2e897cb7f10f0d0f6 253 Pfam PF00005 ABC transporter 23 178 2.5E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_03825 eddbdf9777f9179e373a36155cb000e6 150 Pfam PF07719 Tetratricopeptide repeat 8 39 8.8E-7 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 HL41_03825 eddbdf9777f9179e373a36155cb000e6 150 Pfam PF13432 Tetratricopeptide repeat 46 102 1.8E-10 T 14-10-2018 HL41_03825 eddbdf9777f9179e373a36155cb000e6 150 SUPERFAMILY SSF48452 6 140 2.81E-32 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_03825 eddbdf9777f9179e373a36155cb000e6 150 Gene3D G3DSA:1.25.40.10 2 148 4.8E-34 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_03825 eddbdf9777f9179e373a36155cb000e6 150 SMART SM00028 6 39 4.5E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03825 eddbdf9777f9179e373a36155cb000e6 150 SMART SM00028 74 107 3.1E-7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03825 eddbdf9777f9179e373a36155cb000e6 150 SMART SM00028 40 73 2.8E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_02830 9dcf35fbe05f751967b983849e748f9a 296 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 4 291 5.1E-93 T 14-10-2018 IPR010099 Epimerase family protein SDR39U1 HL41_02830 9dcf35fbe05f751967b983849e748f9a 296 SUPERFAMILY SSF51735 2 248 4.43E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_02830 9dcf35fbe05f751967b983849e748f9a 296 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 213 9.1E-22 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HL41_02830 9dcf35fbe05f751967b983849e748f9a 296 Pfam PF08338 Domain of unknown function (DUF1731) 248 293 7.1E-12 T 14-10-2018 IPR013549 Domain of unknown function DUF1731 HL41_02830 9dcf35fbe05f751967b983849e748f9a 296 Gene3D G3DSA:3.40.50.720 1 285 3.5E-77 T 14-10-2018 HL41_03270 0be4c4f72fb4dca413c383140630bad2 376 PIRSF PIRSF000390 6 376 2.0E-92 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HL41_03270 0be4c4f72fb4dca413c383140630bad2 376 SUPERFAMILY SSF53383 12 373 9.01E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_03270 0be4c4f72fb4dca413c383140630bad2 376 Gene3D G3DSA:3.40.640.10 1 249 5.4E-71 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_03270 0be4c4f72fb4dca413c383140630bad2 376 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 368 1.2E-98 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HL41_03270 0be4c4f72fb4dca413c383140630bad2 376 Gene3D G3DSA:3.90.1150.10 253 375 5.8E-36 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_06020 855b339f2bcf03c487a3f0cfb2f70a25 383 SUPERFAMILY SSF56935 132 321 4.76E-6 T 14-10-2018 HL41_06020 855b339f2bcf03c487a3f0cfb2f70a25 383 Pfam PF04966 Carbohydrate-selective porin, OprB family 110 346 1.4E-10 T 14-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 HL41_06020 855b339f2bcf03c487a3f0cfb2f70a25 383 Gene3D G3DSA:2.40.160.180 63 383 8.9E-10 T 14-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily HL41_00825 fece678370aef31f37629505f89b95c0 473 SUPERFAMILY SSF101821 113 250 8.42E-32 T 14-10-2018 HL41_00825 fece678370aef31f37629505f89b95c0 473 SUPERFAMILY SSF53187 25 472 1.59E-85 T 14-10-2018 HL41_00825 fece678370aef31f37629505f89b95c0 473 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 47 471 1.7E-89 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HL41_00825 fece678370aef31f37629505f89b95c0 473 Gene3D G3DSA:2.30.250.10 112 254 8.2E-138 T 14-10-2018 IPR023358 Peptidase M18, domain 2 GO:0004177 HL41_00825 fece678370aef31f37629505f89b95c0 473 Gene3D G3DSA:3.40.630.10 46 470 8.2E-138 T 14-10-2018 HL41_00825 fece678370aef31f37629505f89b95c0 473 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 438 453 8.2E-28 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HL41_00825 fece678370aef31f37629505f89b95c0 473 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 170 187 8.2E-28 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HL41_00825 fece678370aef31f37629505f89b95c0 473 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 101 117 8.2E-28 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HL41_00825 fece678370aef31f37629505f89b95c0 473 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 134 154 8.2E-28 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HL41_00825 fece678370aef31f37629505f89b95c0 473 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 344 360 8.2E-28 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HL41_00825 fece678370aef31f37629505f89b95c0 473 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 299 317 8.2E-28 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HL41_05105 9bb404687d1fcdea2b81f5ec701df903 205 Pfam PF09335 SNARE associated Golgi protein 37 166 8.5E-16 T 14-10-2018 IPR032816 SNARE associated Golgi protein HL41_08740 1b36047874779919612fda2423d3119d 531 SUPERFAMILY SSF103190 67 163 5.89E-7 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily HL41_08740 1b36047874779919612fda2423d3119d 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 474 8.8E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08740 1b36047874779919612fda2423d3119d 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 488 8.8E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08740 1b36047874779919612fda2423d3119d 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 526 8.8E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08740 1b36047874779919612fda2423d3119d 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 507 8.8E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_08740 1b36047874779919612fda2423d3119d 531 SUPERFAMILY SSF55874 372 527 1.44E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_08740 1b36047874779919612fda2423d3119d 531 Gene3D G3DSA:3.30.565.10 382 530 1.9E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_08740 1b36047874779919612fda2423d3119d 531 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 424 527 4.5E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_08740 1b36047874779919612fda2423d3119d 531 Gene3D G3DSA:1.10.287.130 300 378 4.1E-16 T 14-10-2018 HL41_08740 1b36047874779919612fda2423d3119d 531 Pfam PF00512 His Kinase A (phospho-acceptor) domain 318 377 5.1E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_08740 1b36047874779919612fda2423d3119d 531 SMART SM00387 423 529 1.4E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_08740 1b36047874779919612fda2423d3119d 531 SUPERFAMILY SSF47384 312 377 9.02E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HL41_08740 1b36047874779919612fda2423d3119d 531 SMART SM00388 316 381 4.0E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_06155 d2ff828ba2b682361cd5ef6ca496d19c 133 Pfam PF13380 CoA binding domain 9 124 4.8E-39 T 14-10-2018 IPR003781 CoA-binding GO:0048037 HL41_06155 d2ff828ba2b682361cd5ef6ca496d19c 133 Gene3D G3DSA:3.40.50.720 2 130 2.2E-41 T 14-10-2018 HL41_06155 d2ff828ba2b682361cd5ef6ca496d19c 133 SMART SM00881 5 99 1.5E-22 T 14-10-2018 IPR003781 CoA-binding GO:0048037 HL41_06155 d2ff828ba2b682361cd5ef6ca496d19c 133 SUPERFAMILY SSF51735 6 126 1.58E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_05585 4632fe7b82200af95a113f20c1394e17 420 SUPERFAMILY SSF53633 3 242 7.2E-75 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HL41_05585 4632fe7b82200af95a113f20c1394e17 420 Pfam PF00696 Amino acid kinase family 1 228 6.2E-52 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 ProSitePatterns PS00324 Aspartokinase signature. 4 12 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 Gene3D G3DSA:3.40.1160.10 1 252 2.3E-89 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily HL41_05585 4632fe7b82200af95a113f20c1394e17 420 Gene3D G3DSA:3.30.70.260 259 336 1.7E-61 T 14-10-2018 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 Pfam PF01842 ACT domain 263 324 2.7E-12 T 14-10-2018 IPR002912 ACT domain HL41_05585 4632fe7b82200af95a113f20c1394e17 420 PIRSF PIRSF000726 1 62 1.5E-22 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 PIRSF PIRSF000726 56 408 3.9E-138 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 Gene3D G3DSA:3.30.70.260 253 401 1.7E-61 T 14-10-2018 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 PRINTS PR00474 Glutamate 5-kinase family signature 32 46 8.1E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 PRINTS PR00474 Glutamate 5-kinase family signature 151 178 8.1E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 401 2.9E-139 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 400 6.0E-125 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 SUPERFAMILY SSF55021 246 324 1.17E-18 T 14-10-2018 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 SUPERFAMILY SSF55021 327 406 3.97E-26 T 14-10-2018 HL41_05585 4632fe7b82200af95a113f20c1394e17 420 Pfam PF13840 ACT domain 335 397 1.7E-17 T 14-10-2018 IPR027795 CASTOR, ACT domain HL41_02030 4c25d87c90ae5a1542a5a0f4f4285163 255 SUPERFAMILY SSF53335 59 183 4.99E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_02030 4c25d87c90ae5a1542a5a0f4f4285163 255 Gene3D G3DSA:3.40.50.150 66 254 1.3E-33 T 14-10-2018 HL41_02030 4c25d87c90ae5a1542a5a0f4f4285163 255 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 51 253 7.9E-29 T 14-10-2018 HL41_06720 66cdaee5ff8a5e36f7c13327c713697d 187 Pfam PF00156 Phosphoribosyl transferase domain 20 160 2.6E-21 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HL41_06720 66cdaee5ff8a5e36f7c13327c713697d 187 Gene3D G3DSA:3.40.50.2020 3 186 4.9E-51 T 14-10-2018 HL41_06720 66cdaee5ff8a5e36f7c13327c713697d 187 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 11 185 28.435 T 14-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 HL41_06720 66cdaee5ff8a5e36f7c13327c713697d 187 SUPERFAMILY SSF53271 11 180 2.49E-36 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like HL41_02115 a4c16a8736937c764b02f197a203d50e 367 PIRSF PIRSF018774 2 364 8.8E-166 T 14-10-2018 IPR012375 Glutamate synthase large subunit domain 1 stand-alone protein HL41_02115 a4c16a8736937c764b02f197a203d50e 367 SUPERFAMILY SSF56235 11 356 2.4E-81 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HL41_02115 a4c16a8736937c764b02f197a203d50e 367 Gene3D G3DSA:3.60.20.10 60 366 4.1E-50 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HL41_02115 a4c16a8736937c764b02f197a203d50e 367 Pfam PF00310 Glutamine amidotransferases class-II 102 329 7.8E-11 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain HL41_07555 c165f2cb1562855e065e9c6d9b0c08fe 69 SUPERFAMILY SSF55008 1 68 3.27E-14 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 HL41_07555 c165f2cb1562855e065e9c6d9b0c08fe 69 Pfam PF00403 Heavy-metal-associated domain 6 66 3.5E-9 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HL41_07555 c165f2cb1562855e065e9c6d9b0c08fe 69 Gene3D G3DSA:3.30.70.100 1 69 1.3E-13 T 14-10-2018 HL41_08255 94d0371ffb9247d8bd0f39d6ece7dffc 173 SUPERFAMILY SSF54631 5 166 1.64E-19 T 14-10-2018 HL41_08255 94d0371ffb9247d8bd0f39d6ece7dffc 173 Pfam PF00571 CBS domain 113 166 4.1E-4 T 14-10-2018 IPR000644 CBS domain HL41_08255 94d0371ffb9247d8bd0f39d6ece7dffc 173 Gene3D G3DSA:3.10.580.10 3 169 1.1E-20 T 14-10-2018 HL41_01350 e38c029d84cc7d7f77e01a0941a76bc5 184 Hamap MF_00040 Ribosome-recycling factor [frr]. 2 184 26.321 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 HL41_01350 e38c029d84cc7d7f77e01a0941a76bc5 184 Gene3D G3DSA:3.30.1360.40 30 104 5.4E-68 T 14-10-2018 HL41_01350 e38c029d84cc7d7f77e01a0941a76bc5 184 TIGRFAM TIGR00496 frr: ribosome recycling factor 9 184 2.2E-66 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 HL41_01350 e38c029d84cc7d7f77e01a0941a76bc5 184 Pfam PF01765 Ribosome recycling factor 19 182 8.9E-62 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 HL41_01350 e38c029d84cc7d7f77e01a0941a76bc5 184 SUPERFAMILY SSF55194 2 182 1.09E-67 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 HL41_01350 e38c029d84cc7d7f77e01a0941a76bc5 184 Gene3D G3DSA:1.10.132.20 11 181 5.4E-68 T 14-10-2018 HL41_07200 cfb139d05eb1c9c7f4c340b7b148fcbc 497 Gene3D G3DSA:3.60.120.10 2 495 6.8E-179 T 14-10-2018 IPR005801 ADC synthase GO:0009058 HL41_07200 cfb139d05eb1c9c7f4c340b7b148fcbc 497 Pfam PF00425 chorismate binding enzyme 229 482 7.9E-99 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal HL41_07200 cfb139d05eb1c9c7f4c340b7b148fcbc 497 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 31 491 2.7E-166 T 14-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HL41_07200 cfb139d05eb1c9c7f4c340b7b148fcbc 497 PRINTS PR00095 Anthranilate synthase component I signature 424 438 2.3E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HL41_07200 cfb139d05eb1c9c7f4c340b7b148fcbc 497 PRINTS PR00095 Anthranilate synthase component I signature 439 453 2.3E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HL41_07200 cfb139d05eb1c9c7f4c340b7b148fcbc 497 PRINTS PR00095 Anthranilate synthase component I signature 330 343 2.3E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HL41_07200 cfb139d05eb1c9c7f4c340b7b148fcbc 497 PRINTS PR00095 Anthranilate synthase component I signature 344 357 2.3E-23 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HL41_07200 cfb139d05eb1c9c7f4c340b7b148fcbc 497 Pfam PF04715 Anthranilate synthase component I, N terminal region 31 174 3.4E-33 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HL41_07200 cfb139d05eb1c9c7f4c340b7b148fcbc 497 SUPERFAMILY SSF56322 19 491 6.28E-160 T 14-10-2018 IPR005801 ADC synthase GO:0009058 HL41_01415 d49a2dbf3e3cac110a2ab8cbb9df0e73 347 Pfam PF02481 DNA recombination-mediator protein A 51 256 3.0E-78 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 HL41_01415 d49a2dbf3e3cac110a2ab8cbb9df0e73 347 SUPERFAMILY SSF102405 61 266 1.47E-43 T 14-10-2018 HL41_01415 d49a2dbf3e3cac110a2ab8cbb9df0e73 347 Gene3D G3DSA:3.40.50.450 11 268 1.2E-93 T 14-10-2018 HL41_01415 d49a2dbf3e3cac110a2ab8cbb9df0e73 347 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 52 266 2.1E-76 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 HL41_01415 d49a2dbf3e3cac110a2ab8cbb9df0e73 347 Gene3D G3DSA:1.10.10.10 272 345 7.5E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_07325 a33be67c36a76782d578267d72b92fe2 182 SUPERFAMILY SSF53323 1 179 2.09E-50 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HL41_07325 a33be67c36a76782d578267d72b92fe2 182 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 2.5E-67 T 14-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 HL41_07325 a33be67c36a76782d578267d72b92fe2 182 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 176 6.4E-39 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HL41_07325 a33be67c36a76782d578267d72b92fe2 182 Gene3D G3DSA:3.40.920.10 1 181 2.4E-67 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HL41_02235 a33be67c36a76782d578267d72b92fe2 182 SUPERFAMILY SSF53323 1 179 2.09E-50 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HL41_02235 a33be67c36a76782d578267d72b92fe2 182 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 2.5E-67 T 14-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 HL41_02235 a33be67c36a76782d578267d72b92fe2 182 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 176 6.4E-39 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HL41_02235 a33be67c36a76782d578267d72b92fe2 182 Gene3D G3DSA:3.40.920.10 1 181 2.4E-67 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HL41_04660 b2b9c125cea2c1e6091401439a030622 351 PIRSF PIRSF005378 1 349 3.7E-89 T 14-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 HL41_04660 b2b9c125cea2c1e6091401439a030622 351 Gene3D G3DSA:3.65.10.20 4 330 1.8E-97 T 14-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily HL41_04660 b2b9c125cea2c1e6091401439a030622 351 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 342 34.649 T 14-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 HL41_04660 b2b9c125cea2c1e6091401439a030622 351 SUPERFAMILY SSF55205 1 174 3.14E-51 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HL41_04660 b2b9c125cea2c1e6091401439a030622 351 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 3 330 7.1E-92 T 14-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 HL41_04660 b2b9c125cea2c1e6091401439a030622 351 SUPERFAMILY SSF52913 196 279 6.8E-12 T 14-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily HL41_04660 b2b9c125cea2c1e6091401439a030622 351 Pfam PF01137 RNA 3'-terminal phosphate cyclase 8 330 5.9E-66 T 14-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain HL41_04660 b2b9c125cea2c1e6091401439a030622 351 Gene3D G3DSA:3.30.360.20 182 277 1.8E-97 T 14-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily HL41_04660 b2b9c125cea2c1e6091401439a030622 351 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 193 272 4.2E-6 T 14-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain HL41_01775 ed49849b78488011c175abdbd7786141 470 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 458 1.1E-109 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 HL41_01775 ed49849b78488011c175abdbd7786141 470 SUPERFAMILY SSF56954 2 459 1.24E-110 T 14-10-2018 HL41_01775 ed49849b78488011c175abdbd7786141 470 Gene3D G3DSA:2.20.200.10 95 347 3.0E-129 T 14-10-2018 HL41_01775 ed49849b78488011c175abdbd7786141 470 Gene3D G3DSA:1.20.1600.10 48 459 3.0E-129 T 14-10-2018 HL41_01775 ed49849b78488011c175abdbd7786141 470 Pfam PF02321 Outer membrane efflux protein 275 456 3.5E-34 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 HL41_01775 ed49849b78488011c175abdbd7786141 470 Pfam PF02321 Outer membrane efflux protein 58 246 2.4E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 HL41_07815 069a8f0457815c38f82c336c2ca39ac9 403 SUPERFAMILY SSF102645 186 401 4.32E-55 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 HL41_07815 069a8f0457815c38f82c336c2ca39ac9 403 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 190 367 4.0E-52 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 HL41_07815 069a8f0457815c38f82c336c2ca39ac9 403 SUPERFAMILY SSF52507 6 182 7.85E-58 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 HL41_07815 069a8f0457815c38f82c336c2ca39ac9 403 Gene3D G3DSA:3.40.50.10300 188 403 1.1E-57 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 HL41_07815 069a8f0457815c38f82c336c2ca39ac9 403 Pfam PF02441 Flavoprotein 10 180 1.1E-43 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HL41_07815 069a8f0457815c38f82c336c2ca39ac9 403 Gene3D G3DSA:3.40.50.1950 2 187 4.7E-59 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 HL41_07815 069a8f0457815c38f82c336c2ca39ac9 403 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 6 401 2.7E-112 T 14-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 HL41_01075 b32e3da23902f9670a84b0d60f3d8cc6 198 Pfam PF00430 ATP synthase B/B' CF(0) 43 172 9.1E-19 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HL41_01075 b32e3da23902f9670a84b0d60f3d8cc6 198 Hamap MF_01398 ATP synthase subunit b [atpF]. 34 174 12.371 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HL41_01075 b32e3da23902f9670a84b0d60f3d8cc6 198 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 47 191 1.9E-21 T 14-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 HL41_03740 ca14f968e34e7b6764391bf91058721b 163 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 143 2.7E-35 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_03740 ca14f968e34e7b6764391bf91058721b 163 Gene3D G3DSA:3.40.980.10 1 162 8.6E-57 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily HL41_03740 ca14f968e34e7b6764391bf91058721b 163 Pfam PF00994 Probable molybdopterin binding domain 5 148 8.5E-37 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_03740 ca14f968e34e7b6764391bf91058721b 163 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 65 78 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 HL41_03740 ca14f968e34e7b6764391bf91058721b 163 SUPERFAMILY SSF53218 1 154 3.8E-45 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily HL41_03740 ca14f968e34e7b6764391bf91058721b 163 SMART SM00852 5 149 1.3E-26 T 14-10-2018 IPR001453 MoaB/Mog domain HL41_07625 4bf260aa5dee0e421f2916b70fb7b517 738 Gene3D G3DSA:3.30.1650.10 322 505 5.2E-73 T 14-10-2018 IPR038571 Bifunctional carbon monoxide dehydrogenase/acetyl-coa synthase, domain 3 superfamily KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 HL41_07625 4bf260aa5dee0e421f2916b70fb7b517 738 Pfam PF03598 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 324 484 3.7E-65 T 14-10-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 HL41_07625 4bf260aa5dee0e421f2916b70fb7b517 738 TIGRFAM TIGR00316 cdhC: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit 322 732 3.6E-140 T 14-10-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 HL41_07625 4bf260aa5dee0e421f2916b70fb7b517 738 SUPERFAMILY SSF56821 14 737 3.71E-244 T 14-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 HL41_07625 4bf260aa5dee0e421f2916b70fb7b517 738 Gene3D G3DSA:3.40.1470.10 609 737 8.9E-53 T 14-10-2018 HL41_07625 4bf260aa5dee0e421f2916b70fb7b517 738 Gene3D G3DSA:1.10.8.190 2 110 1.0E-30 T 14-10-2018 HL41_07625 4bf260aa5dee0e421f2916b70fb7b517 738 Gene3D G3DSA:3.40.970.20 506 594 5.0E-41 T 14-10-2018 HL41_07625 4bf260aa5dee0e421f2916b70fb7b517 738 Gene3D G3DSA:3.40.50.2030 116 315 6.9E-61 T 14-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HL41_00195 357771409415eee19b22d04f44bcb803 266 Pfam PF01478 Type IV leader peptidase family 110 218 8.3E-20 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 HL41_00195 357771409415eee19b22d04f44bcb803 266 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 188 199 2.0E-10 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial HL41_00195 357771409415eee19b22d04f44bcb803 266 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 118 135 2.0E-10 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial HL41_00195 357771409415eee19b22d04f44bcb803 266 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 177 187 2.0E-10 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial HL41_00195 357771409415eee19b22d04f44bcb803 266 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 200 215 2.0E-10 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial HL41_00195 357771409415eee19b22d04f44bcb803 266 Gene3D G3DSA:1.20.120.1220 99 229 2.1E-8 T 14-10-2018 HL41_00195 357771409415eee19b22d04f44bcb803 266 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 12 96 2.9E-30 T 14-10-2018 IPR010627 Peptidase A24A, N-terminal HL41_00285 86038678ac094e57b502030489ca6e41 556 TIGRFAM TIGR00337 PyrG: CTP synthase 12 547 3.3E-249 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 HL41_00285 86038678ac094e57b502030489ca6e41 556 Gene3D G3DSA:3.40.50.300 3 294 4.8E-129 T 14-10-2018 HL41_00285 86038678ac094e57b502030489ca6e41 556 Pfam PF06418 CTP synthase N-terminus 13 276 2.5E-125 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 HL41_00285 86038678ac094e57b502030489ca6e41 556 SUPERFAMILY SSF52317 298 553 2.45E-87 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_00285 86038678ac094e57b502030489ca6e41 556 SUPERFAMILY SSF52540 12 280 6.64E-123 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00285 86038678ac094e57b502030489ca6e41 556 Gene3D G3DSA:3.40.50.880 295 555 3.7E-105 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_00285 86038678ac094e57b502030489ca6e41 556 Pfam PF00117 Glutamine amidotransferase class-I 311 547 2.5E-56 T 14-10-2018 IPR017926 Glutamine amidotransferase HL41_00285 86038678ac094e57b502030489ca6e41 556 Hamap MF_01227 CTP synthase [pyrG]. 12 552 52.297 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 Hamap MF_00416 Flagellar P-ring protein [flgI]. 3 365 37.281 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 PRINTS PR01010 Flagellar P-ring protein signature 57 72 5.6E-73 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 PRINTS PR01010 Flagellar P-ring protein signature 23 38 5.6E-73 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 PRINTS PR01010 Flagellar P-ring protein signature 121 139 5.6E-73 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 PRINTS PR01010 Flagellar P-ring protein signature 252 264 5.6E-73 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 PRINTS PR01010 Flagellar P-ring protein signature 104 121 5.6E-73 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 PRINTS PR01010 Flagellar P-ring protein signature 38 53 5.6E-73 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 PRINTS PR01010 Flagellar P-ring protein signature 82 101 5.6E-73 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 PRINTS PR01010 Flagellar P-ring protein signature 161 179 5.6E-73 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_00980 0d9f317ce79249b0fdaa76a49aaf4068 365 Pfam PF02119 Flagellar P-ring protein 23 364 4.9E-146 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HL41_04585 6eb899e0d98a28ce1ecfbf3595f7163c 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 185 5.8E-32 T 14-10-2018 HL41_04585 6eb899e0d98a28ce1ecfbf3595f7163c 219 Gene3D G3DSA:3.40.50.1000 5 199 9.8E-50 T 14-10-2018 IPR023214 HAD superfamily HL41_04585 6eb899e0d98a28ce1ecfbf3595f7163c 219 Gene3D G3DSA:1.10.150.240 17 87 9.8E-50 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 HL41_04585 6eb899e0d98a28ce1ecfbf3595f7163c 219 SUPERFAMILY SSF56784 4 213 6.94E-47 T 14-10-2018 IPR036412 HAD-like superfamily HL41_04585 6eb899e0d98a28ce1ecfbf3595f7163c 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 184 8.3E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 HL41_02375 a814c38b49a021395258c5b69ccc3299 217 SUPERFAMILY SSF69572 3 215 2.62E-66 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 HL41_02375 a814c38b49a021395258c5b69ccc3299 217 Gene3D G3DSA:3.40.50.720 1 216 1.3E-59 T 14-10-2018 HL41_02375 a814c38b49a021395258c5b69ccc3299 217 Pfam PF00899 ThiF family 5 215 5.2E-50 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HL41_06890 aabbfe385d6b77cfafcb14f195d7e488 231 ProSitePatterns PS00501 Signal peptidases I serine active site. 147 154 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 HL41_06890 aabbfe385d6b77cfafcb14f195d7e488 231 Pfam PF01381 Helix-turn-helix 17 72 6.8E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HL41_06890 aabbfe385d6b77cfafcb14f195d7e488 231 SMART SM00530 16 72 2.1E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HL41_06890 aabbfe385d6b77cfafcb14f195d7e488 231 Gene3D G3DSA:2.10.109.10 108 230 3.7E-15 T 14-10-2018 HL41_06890 aabbfe385d6b77cfafcb14f195d7e488 231 Pfam PF00717 Peptidase S24-like 144 212 1.6E-11 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HL41_06890 aabbfe385d6b77cfafcb14f195d7e488 231 SUPERFAMILY SSF47413 12 77 3.75E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HL41_06890 aabbfe385d6b77cfafcb14f195d7e488 231 Gene3D G3DSA:1.10.260.40 14 99 1.0E-12 T 14-10-2018 HL41_06890 aabbfe385d6b77cfafcb14f195d7e488 231 SUPERFAMILY SSF51306 102 226 2.49E-22 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily HL41_05405 752afc3ef09ecb0138bb95479e42e439 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 4.7E-24 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05405 752afc3ef09ecb0138bb95479e42e439 65 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 14-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05405 752afc3ef09ecb0138bb95479e42e439 65 Pfam PF00831 Ribosomal L29 protein 5 60 2.2E-26 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05405 752afc3ef09ecb0138bb95479e42e439 65 Gene3D G3DSA:1.10.287.310 1 65 5.6E-28 T 14-10-2018 HL41_05405 752afc3ef09ecb0138bb95479e42e439 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.805 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05405 752afc3ef09ecb0138bb95479e42e439 65 SUPERFAMILY SSF46561 1 63 1.22E-23 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_02395 6a5aea6185fdb6eea7f6bf2fae4e0aa4 339 PIRSF PIRSF000267 1 339 1.5E-118 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 HL41_02395 6a5aea6185fdb6eea7f6bf2fae4e0aa4 339 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 330 6.3E-101 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 HL41_02395 6a5aea6185fdb6eea7f6bf2fae4e0aa4 339 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 211 3.7E-69 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 HL41_08730 5778ddf2ceed53ba3e22012fee50d184 652 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 455 594 3.3E-31 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_08730 5778ddf2ceed53ba3e22012fee50d184 652 SMART SM00304 335 389 5.0E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HL41_08730 5778ddf2ceed53ba3e22012fee50d184 652 Gene3D G3DSA:1.10.287.950 334 652 2.0E-53 T 14-10-2018 HL41_08730 5778ddf2ceed53ba3e22012fee50d184 652 SMART SM00283 397 651 2.9E-34 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_08730 5778ddf2ceed53ba3e22012fee50d184 652 SUPERFAMILY SSF58104 357 651 9.94E-59 T 14-10-2018 HL41_08730 5778ddf2ceed53ba3e22012fee50d184 652 Pfam PF14827 Double sensory domain of two-component sensor kinase 125 298 8.1E-15 T 14-10-2018 IPR029150 Double Cache domain 3 HL41_05165 173aedcf689cd342019e2769f3a6bc39 293 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 2 292 2.9E-65 T 14-10-2018 IPR005229 Conserved hypothetical protein CHP00255 HL41_05165 173aedcf689cd342019e2769f3a6bc39 293 Pfam PF03755 YicC-like family, N-terminal region 1 155 3.3E-38 T 14-10-2018 IPR013527 YicC-like, N-terminal HL41_05165 173aedcf689cd342019e2769f3a6bc39 293 Pfam PF08340 Domain of unknown function (DUF1732) 210 292 5.3E-30 T 14-10-2018 IPR013551 Domain of unknown function DUF1732 HL41_07215 85876aecfaa63bd7a5398f14022521a5 672 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 644 1.7E-164 T 14-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HL41_07215 85876aecfaa63bd7a5398f14022521a5 672 Pfam PF07670 Nucleoside recognition 481 646 2.5E-23 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HL41_07215 85876aecfaa63bd7a5398f14022521a5 672 Pfam PF07670 Nucleoside recognition 321 409 3.8E-9 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HL41_07215 85876aecfaa63bd7a5398f14022521a5 672 Gene3D G3DSA:3.40.50.300 3 193 1.0E-42 T 14-10-2018 HL41_07215 85876aecfaa63bd7a5398f14022521a5 672 Pfam PF07664 Ferrous iron transport protein B C terminus 424 470 1.0E-16 T 14-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 HL41_07215 85876aecfaa63bd7a5398f14022521a5 672 SUPERFAMILY SSF52540 4 178 1.88E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07215 85876aecfaa63bd7a5398f14022521a5 672 Pfam PF02421 Ferrous iron transport protein B 4 158 1.1E-58 T 14-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 HL41_07895 47e91a09bb8ecc099a8e6546a83d9aab 251 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 70 196 2.4E-10 T 14-10-2018 HL41_07895 47e91a09bb8ecc099a8e6546a83d9aab 251 Gene3D G3DSA:1.10.510.10 111 186 1.6E-6 T 14-10-2018 HL41_07895 47e91a09bb8ecc099a8e6546a83d9aab 251 SUPERFAMILY SSF56112 57 214 4.7E-12 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily HL41_01510 885f82cfc7da30b808379ff23a2bb939 99 SUPERFAMILY SSF102829 11 91 8.89E-6 T 14-10-2018 IPR036192 Cell division protein ZapA-like superfamily HL41_01510 885f82cfc7da30b808379ff23a2bb939 99 Pfam PF05164 Cell division protein ZapA 11 78 8.2E-7 T 14-10-2018 IPR007838 Cell division protein ZapA-like HL41_07530 5fa72f989690fda956d2f5c73eb89e01 478 Pfam PF01435 Peptidase family M48 73 242 9.1E-26 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HL41_07530 5fa72f989690fda956d2f5c73eb89e01 478 Gene3D G3DSA:1.25.40.10 366 478 5.9E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_07530 5fa72f989690fda956d2f5c73eb89e01 478 Pfam PF14559 Tetratricopeptide repeat 315 363 4.8E-7 T 14-10-2018 HL41_07530 5fa72f989690fda956d2f5c73eb89e01 478 Gene3D G3DSA:1.25.40.10 253 364 4.1E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_07530 5fa72f989690fda956d2f5c73eb89e01 478 SUPERFAMILY SSF48452 292 458 1.0E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_07205 464407a3c72d517b53f55f7ef7319bf3 436 PIRSF PIRSF001549 1 434 8.1E-112 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 HL41_07205 464407a3c72d517b53f55f7ef7319bf3 436 Pfam PF13393 Histidyl-tRNA synthetase 8 313 2.1E-36 T 14-10-2018 HL41_07205 464407a3c72d517b53f55f7ef7319bf3 436 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 433 31.001 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 HL41_07205 464407a3c72d517b53f55f7ef7319bf3 436 SUPERFAMILY SSF55681 3 320 5.94E-90 T 14-10-2018 HL41_07205 464407a3c72d517b53f55f7ef7319bf3 436 Pfam PF03129 Anticodon binding domain 357 427 6.4E-10 T 14-10-2018 IPR004154 Anticodon-binding HL41_07205 464407a3c72d517b53f55f7ef7319bf3 436 Gene3D G3DSA:3.40.50.800 339 435 2.3E-21 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily HL41_07205 464407a3c72d517b53f55f7ef7319bf3 436 Gene3D G3DSA:3.30.930.10 1 322 5.6E-106 T 14-10-2018 HL41_07205 464407a3c72d517b53f55f7ef7319bf3 436 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 418 8.5E-138 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 HL41_07205 464407a3c72d517b53f55f7ef7319bf3 436 SUPERFAMILY SSF52954 339 430 3.47E-18 T 14-10-2018 HL41_00915 264a4fa014c341cc46bb8f6f82427f4c 245 SUPERFAMILY SSF75217 67 243 2.09E-49 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases HL41_00915 264a4fa014c341cc46bb8f6f82427f4c 245 Gene3D G3DSA:3.30.1330.30 1 73 1.9E-9 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like HL41_00915 264a4fa014c341cc46bb8f6f82427f4c 245 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 1 242 7.6E-73 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 HL41_00915 264a4fa014c341cc46bb8f6f82427f4c 245 Gene3D G3DSA:3.40.1280.10 75 243 5.0E-59 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HL41_00915 264a4fa014c341cc46bb8f6f82427f4c 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 4 72 1.6E-13 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HL41_00915 264a4fa014c341cc46bb8f6f82427f4c 245 SUPERFAMILY SSF55315 3 71 2.71E-11 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like HL41_00915 264a4fa014c341cc46bb8f6f82427f4c 245 SMART SM00967 4 79 4.0E-9 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HL41_00915 264a4fa014c341cc46bb8f6f82427f4c 245 Pfam PF00588 SpoU rRNA Methylase family 96 236 4.9E-42 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HL41_08865 1a9cc48f65fbed8e67b094323bbe6b3d 286 PRINTS PR01438 Universal stress protein signature 4 22 2.5E-16 T 14-10-2018 IPR006015 Universal stress protein A HL41_08865 1a9cc48f65fbed8e67b094323bbe6b3d 286 PRINTS PR01438 Universal stress protein signature 120 142 2.5E-16 T 14-10-2018 IPR006015 Universal stress protein A HL41_08865 1a9cc48f65fbed8e67b094323bbe6b3d 286 PRINTS PR01438 Universal stress protein signature 102 114 2.5E-16 T 14-10-2018 IPR006015 Universal stress protein A HL41_08865 1a9cc48f65fbed8e67b094323bbe6b3d 286 SUPERFAMILY SSF52402 150 284 4.86E-23 T 14-10-2018 HL41_08865 1a9cc48f65fbed8e67b094323bbe6b3d 286 SUPERFAMILY SSF52402 4 144 2.3E-31 T 14-10-2018 HL41_08865 1a9cc48f65fbed8e67b094323bbe6b3d 286 Gene3D G3DSA:3.40.50.620 147 284 1.1E-23 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_08865 1a9cc48f65fbed8e67b094323bbe6b3d 286 Gene3D G3DSA:3.40.50.620 2 145 1.6E-32 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_08865 1a9cc48f65fbed8e67b094323bbe6b3d 286 Pfam PF00582 Universal stress protein family 149 282 6.8E-20 T 14-10-2018 IPR006016 UspA HL41_08865 1a9cc48f65fbed8e67b094323bbe6b3d 286 Pfam PF00582 Universal stress protein family 4 142 4.4E-30 T 14-10-2018 IPR006016 UspA HL41_07865 40d6829f18689e7c34f7e781fdbc1ad1 397 SUPERFAMILY SSF102114 12 336 1.08E-25 T 14-10-2018 HL41_07865 40d6829f18689e7c34f7e781fdbc1ad1 397 Gene3D G3DSA:3.20.20.70 14 373 7.1E-33 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_07865 40d6829f18689e7c34f7e781fdbc1ad1 397 Pfam PF13353 4Fe-4S single cluster domain 21 143 6.2E-9 T 14-10-2018 HL41_07865 40d6829f18689e7c34f7e781fdbc1ad1 397 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 276 341 9.6E-7 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain HL41_02790 ea473ba24eaeba6ab9190d7b9965bb5f 182 Gene3D G3DSA:3.40.220.10 4 181 4.4E-70 T 14-10-2018 HL41_02790 ea473ba24eaeba6ab9190d7b9965bb5f 182 SMART SM00506 9 139 1.3E-47 T 14-10-2018 IPR002589 Macro domain HL41_02790 ea473ba24eaeba6ab9190d7b9965bb5f 182 Pfam PF01661 Macro domain 26 139 3.1E-41 T 14-10-2018 IPR002589 Macro domain HL41_02790 ea473ba24eaeba6ab9190d7b9965bb5f 182 SUPERFAMILY SSF52949 3 174 3.7E-63 T 14-10-2018 HL41_01445 4e15124c6c7084ea13891286697ea8b4 199 Gene3D G3DSA:3.30.420.10 2 199 1.8E-69 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HL41_01445 4e15124c6c7084ea13891286697ea8b4 199 SUPERFAMILY SSF53098 9 196 2.28E-60 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily HL41_01445 4e15124c6c7084ea13891286697ea8b4 199 Hamap MF_00052_B Ribonuclease HII [rnhB]. 18 198 33.252 T 14-10-2018 IPR022898 Ribonuclease HII GO:0004523 HL41_01445 4e15124c6c7084ea13891286697ea8b4 199 Pfam PF01351 Ribonuclease HII 20 195 3.6E-36 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain HL41_00905 957e877887c02873a1bfc29bcad4534c 93 Hamap MF_01503 UPF0296 protein . 5 91 28.301 T 14-10-2018 IPR007169 Extracellular matrix regulatory protein A HL41_00905 957e877887c02873a1bfc29bcad4534c 93 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 7 78 1.0E-28 T 14-10-2018 IPR007169 Extracellular matrix regulatory protein A HL41_00905 957e877887c02873a1bfc29bcad4534c 93 Pfam PF04025 Domain of unknown function (DUF370) 7 79 6.0E-37 T 14-10-2018 IPR007169 Extracellular matrix regulatory protein A HL41_07345 24e1c611ef9d97d2f85bd8991ebaf1e7 119 SUPERFAMILY SSF143243 5 105 4.32E-13 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_07345 24e1c611ef9d97d2f85bd8991ebaf1e7 119 Gene3D G3DSA:3.30.460.80 2 92 4.2E-11 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_07345 24e1c611ef9d97d2f85bd8991ebaf1e7 119 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 5 102 1.8E-13 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_07345 24e1c611ef9d97d2f85bd8991ebaf1e7 119 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 61 94 8.0E-5 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_02980 1f2465be303c8b79007cc27ad2d8e7ce 139 Pfam PF01584 CheW-like domain 6 138 2.8E-25 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HL41_02980 1f2465be303c8b79007cc27ad2d8e7ce 139 Gene3D G3DSA:2.30.30.40 7 131 1.2E-29 T 14-10-2018 HL41_02980 1f2465be303c8b79007cc27ad2d8e7ce 139 Gene3D G3DSA:2.40.50.180 22 137 1.2E-29 T 14-10-2018 HL41_02980 1f2465be303c8b79007cc27ad2d8e7ce 139 SUPERFAMILY SSF50341 2 138 1.57E-29 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 HL41_02980 1f2465be303c8b79007cc27ad2d8e7ce 139 SMART SM00260 1 137 9.5E-21 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 HL41_05295 5e596c861c10cb43844b737b9015b8ae 484 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 183 241 2.5E-12 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 HL41_05295 5e596c861c10cb43844b737b9015b8ae 484 Pfam PF01743 Poly A polymerase head domain 42 155 5.2E-12 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 HL41_05295 5e596c861c10cb43844b737b9015b8ae 484 SUPERFAMILY SSF81301 39 151 9.48E-20 T 14-10-2018 HL41_05295 5e596c861c10cb43844b737b9015b8ae 484 Gene3D G3DSA:3.30.460.10 15 150 1.8E-23 T 14-10-2018 HL41_05295 5e596c861c10cb43844b737b9015b8ae 484 SUPERFAMILY SSF81891 155 479 2.75E-40 T 14-10-2018 HL41_05295 5e596c861c10cb43844b737b9015b8ae 484 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 429 474 1.9E-8 T 14-10-2018 IPR032810 CCA-adding enzyme, C-terminal HL41_05295 5e596c861c10cb43844b737b9015b8ae 484 Pfam PF01966 HD domain 257 397 4.7E-9 T 14-10-2018 IPR006674 HD domain HL41_05295 5e596c861c10cb43844b737b9015b8ae 484 Gene3D G3DSA:1.10.3090.10 154 474 1.5E-37 T 14-10-2018 HL41_00220 9f7b27ca666b6ed665d7eee70a899b18 141 TIGRFAM TIGR02805 exbB2: tonB-system energizer ExbB 3 136 6.4E-48 T 14-10-2018 IPR014172 TonB-system energizer ExbB type-2 GO:0016020|GO:0055085 HL41_00220 9f7b27ca666b6ed665d7eee70a899b18 141 Pfam PF01618 MotA/TolQ/ExbB proton channel family 49 136 5.7E-28 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel HL41_07350 494094c348be9bb6fb911a86c12c6139 365 Gene3D G3DSA:1.10.645.20 7 365 6.8E-122 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_07350 494094c348be9bb6fb911a86c12c6139 365 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 121 289 3.0E-45 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_07350 494094c348be9bb6fb911a86c12c6139 365 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 291 365 2.8E-18 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_07350 494094c348be9bb6fb911a86c12c6139 365 SUPERFAMILY SSF56762 18 365 2.09E-109 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_07350 494094c348be9bb6fb911a86c12c6139 365 Pfam PF00374 Nickel-dependent hydrogenase 45 112 9.2E-13 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 HL41_09045 fc053eb396a41ea04f06ce31b15e76df 348 Gene3D G3DSA:2.40.440.10 81 267 7.5E-14 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like HL41_09045 fc053eb396a41ea04f06ce31b15e76df 348 Pfam PF03734 L,D-transpeptidase catalytic domain 93 246 2.9E-16 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 HL41_09045 fc053eb396a41ea04f06ce31b15e76df 348 SUPERFAMILY SSF141523 90 247 2.09E-16 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like HL41_04165 1342e449d29ec44446b8baf7c7d23063 293 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 83 1.3E-16 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HL41_04165 1342e449d29ec44446b8baf7c7d23063 293 Gene3D G3DSA:1.10.150.130 2 90 4.9E-19 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal HL41_04165 1342e449d29ec44446b8baf7c7d23063 293 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 293 53.915 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD HL41_04165 1342e449d29ec44446b8baf7c7d23063 293 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 6 293 7.4E-104 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 HL41_04165 1342e449d29ec44446b8baf7c7d23063 293 SUPERFAMILY SSF47823 3 86 1.75E-13 T 14-10-2018 HL41_04165 1342e449d29ec44446b8baf7c7d23063 293 Gene3D G3DSA:1.10.443.10 106 287 2.2E-69 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 HL41_04165 1342e449d29ec44446b8baf7c7d23063 293 Pfam PF00589 Phage integrase family 106 279 6.7E-49 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HL41_04165 1342e449d29ec44446b8baf7c7d23063 293 SUPERFAMILY SSF56349 103 291 1.0E-59 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HL41_04110 337a8917b25e10f36b401342cb360ba0 113 SUPERFAMILY SSF75169 4 112 9.42E-19 T 14-10-2018 IPR027396 DsrEFH-like HL41_04110 337a8917b25e10f36b401342cb360ba0 113 Pfam PF02635 DsrE/DsrF-like family 22 112 8.9E-9 T 14-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein HL41_04110 337a8917b25e10f36b401342cb360ba0 113 Gene3D G3DSA:3.40.1260.10 3 113 7.3E-20 T 14-10-2018 IPR027396 DsrEFH-like HL41_04995 9cab0a622e49dc365632025cf6df7820 242 SMART SM00382 26 214 6.0E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_04995 9cab0a622e49dc365632025cf6df7820 242 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_04995 9cab0a622e49dc365632025cf6df7820 242 SUPERFAMILY SSF52540 1 230 1.68E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04995 9cab0a622e49dc365632025cf6df7820 242 Pfam PF00005 ABC transporter 17 165 6.9E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_04995 9cab0a622e49dc365632025cf6df7820 242 Gene3D G3DSA:3.40.50.300 1 241 3.6E-72 T 14-10-2018 HL41_03015 c73d9c907998fd6cde703e0af26eca69 435 Pfam PF01171 PP-loop family 70 239 5.7E-14 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 HL41_03015 c73d9c907998fd6cde703e0af26eca69 435 Pfam PF00581 Rhodanese-like domain 338 422 9.1E-5 T 14-10-2018 IPR001763 Rhodanese-like domain HL41_03015 c73d9c907998fd6cde703e0af26eca69 435 SUPERFAMILY SSF52821 331 425 8.92E-14 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily HL41_03015 c73d9c907998fd6cde703e0af26eca69 435 Gene3D G3DSA:3.40.250.10 342 428 3.0E-11 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily HL41_03015 c73d9c907998fd6cde703e0af26eca69 435 SUPERFAMILY SSF52402 45 267 7.72E-41 T 14-10-2018 HL41_03015 c73d9c907998fd6cde703e0af26eca69 435 Gene3D G3DSA:3.40.50.620 20 341 6.3E-64 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_04375 cef2b5917033072a65dd56ce4cdb500d 95 SUPERFAMILY SSF56784 10 92 1.22E-13 T 14-10-2018 IPR036412 HAD-like superfamily HL41_04375 cef2b5917033072a65dd56ce4cdb500d 95 Gene3D G3DSA:3.40.50.1000 2 95 1.7E-18 T 14-10-2018 IPR023214 HAD superfamily HL41_04375 cef2b5917033072a65dd56ce4cdb500d 95 Pfam PF02358 Trehalose-phosphatase 2 72 2.4E-14 T 14-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 HL41_03730 883a8e213ee52b05c802a925a57dcf84 370 SMART SM00487 21 220 1.3E-62 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HL41_03730 883a8e213ee52b05c802a925a57dcf84 370 Pfam PF00270 DEAD/DEAH box helicase 26 190 6.5E-50 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HL41_03730 883a8e213ee52b05c802a925a57dcf84 370 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site HL41_03730 883a8e213ee52b05c802a925a57dcf84 370 SMART SM00490 256 337 2.2E-37 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_03730 883a8e213ee52b05c802a925a57dcf84 370 SUPERFAMILY SSF52540 70 357 1.01E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03730 883a8e213ee52b05c802a925a57dcf84 370 Gene3D G3DSA:3.40.50.300 1 209 1.1E-74 T 14-10-2018 HL41_03730 883a8e213ee52b05c802a925a57dcf84 370 Pfam PF00271 Helicase conserved C-terminal domain 229 337 3.0E-32 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_03730 883a8e213ee52b05c802a925a57dcf84 370 Gene3D G3DSA:3.40.50.300 212 369 6.0E-55 T 14-10-2018 HL41_00600 2fcdcea576e4c64d1873f61017e97536 203 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 200 2.4E-55 T 14-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 HL41_00600 2fcdcea576e4c64d1873f61017e97536 203 Pfam PF03358 NADPH-dependent FMN reductase 1 147 9.5E-13 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HL41_00600 2fcdcea576e4c64d1873f61017e97536 203 Gene3D G3DSA:3.40.50.360 1 203 9.9E-65 T 14-10-2018 IPR029039 Flavoprotein-like superfamily HL41_00600 2fcdcea576e4c64d1873f61017e97536 203 SUPERFAMILY SSF52218 1 200 1.23E-53 T 14-10-2018 IPR029039 Flavoprotein-like superfamily HL41_07650 307f224050f769550c98efa024f2d92e 471 Pfam PF13187 4Fe-4S dicluster domain 419 466 2.6E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_07650 307f224050f769550c98efa024f2d92e 471 Gene3D G3DSA:3.30.70.20 441 470 3.4E-6 T 14-10-2018 HL41_07650 307f224050f769550c98efa024f2d92e 471 Gene3D G3DSA:3.30.70.20 399 440 2.7E-5 T 14-10-2018 HL41_07650 307f224050f769550c98efa024f2d92e 471 SUPERFAMILY SSF54862 409 468 3.49E-18 T 14-10-2018 HL41_07650 307f224050f769550c98efa024f2d92e 471 Gene3D G3DSA:3.40.50.2030 176 367 7.5E-12 T 14-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HL41_07650 307f224050f769550c98efa024f2d92e 471 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 451 462 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_04575 6e8b753883731d6302a3ae4471d0219b 152 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 152 76.234 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HL41_04575 6e8b753883731d6302a3ae4471d0219b 152 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 9.2E-57 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HL41_04575 6e8b753883731d6302a3ae4471d0219b 152 Pfam PF03477 ATP cone domain 48 135 4.2E-17 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 Gene3D G3DSA:2.40.50.140 522 628 3.4E-38 T 14-10-2018 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 PRINTS PR01041 Methionyl-tRNA synthetase signature 38 52 1.8E-30 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 PRINTS PR01041 Methionyl-tRNA synthetase signature 223 234 1.8E-30 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 PRINTS PR01041 Methionyl-tRNA synthetase signature 346 357 1.8E-30 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.8E-30 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 PRINTS PR01041 Methionyl-tRNA synthetase signature 86 97 1.8E-30 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 PRINTS PR01041 Methionyl-tRNA synthetase signature 254 269 1.8E-30 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 Pfam PF08264 Anticodon-binding domain of tRNA 380 478 3.0E-8 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 Gene3D G3DSA:3.40.50.620 5 328 1.1E-138 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 SUPERFAMILY SSF50249 528 627 3.67E-32 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 Gene3D G3DSA:2.170.220.10 115 225 1.1E-138 T 14-10-2018 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 Pfam PF01588 Putative tRNA binding domain 535 625 2.6E-26 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 SUPERFAMILY SSF52374 4 345 7.24E-102 T 14-10-2018 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 Pfam PF09334 tRNA synthetases class I (M) 141 359 6.3E-62 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 Pfam PF09334 tRNA synthetases class I (M) 4 140 2.3E-43 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 505 4.3E-147 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 Hamap MF_01228 Methionine--tRNA ligase [metG]. 2 503 42.44 T 14-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 Gene3D G3DSA:1.10.730.10 336 510 3.9E-49 T 14-10-2018 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 SUPERFAMILY SSF47323 348 542 6.73E-42 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_00415 e005eddd472c4a89311db7eb5cbd93e8 628 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 508 627 1.7E-41 T 14-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HL41_00940 9cb9057eb8364aa4c320ea83879ed877 410 Pfam PF02687 FtsX-like permease family 305 399 2.6E-13 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HL41_00940 9cb9057eb8364aa4c320ea83879ed877 410 Pfam PF12704 MacB-like periplasmic core domain 30 236 2.0E-9 T 14-10-2018 IPR025857 MacB-like periplasmic core domain HL41_04060 4c34d6b363ae58b2b8be2b76f493d687 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.8E-21 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04060 4c34d6b363ae58b2b8be2b76f493d687 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.555 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04060 4c34d6b363ae58b2b8be2b76f493d687 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 24 4.0E-4 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04060 4c34d6b363ae58b2b8be2b76f493d687 44 Pfam PF00468 Ribosomal protein L34 1 44 2.3E-22 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_07975 11c0d0867171be9bdd5fb3b001468d84 285 Gene3D G3DSA:3.10.310.10 127 268 2.6E-80 T 14-10-2018 HL41_07975 11c0d0867171be9bdd5fb3b001468d84 285 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 78 92 - T 14-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 HL41_07975 11c0d0867171be9bdd5fb3b001468d84 285 SUPERFAMILY SSF54506 13 135 2.36E-33 T 14-10-2018 HL41_07975 11c0d0867171be9bdd5fb3b001468d84 285 Pfam PF01678 Diaminopimelate epimerase 15 130 4.6E-23 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 HL41_07975 11c0d0867171be9bdd5fb3b001468d84 285 Pfam PF01678 Diaminopimelate epimerase 153 270 1.9E-19 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 HL41_07975 11c0d0867171be9bdd5fb3b001468d84 285 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 13 281 31.606 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 HL41_07975 11c0d0867171be9bdd5fb3b001468d84 285 SUPERFAMILY SSF54506 136 279 2.04E-38 T 14-10-2018 HL41_07975 11c0d0867171be9bdd5fb3b001468d84 285 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 13 280 2.0E-76 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 HL41_07975 11c0d0867171be9bdd5fb3b001468d84 285 Gene3D G3DSA:3.10.310.10 15 277 2.6E-80 T 14-10-2018 HL41_02750 11e91b912aed17862be901b2a09e1690 284 Gene3D G3DSA:3.20.20.20 2 283 3.0E-112 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_02750 11e91b912aed17862be901b2a09e1690 284 SUPERFAMILY SSF51717 7 280 8.24E-102 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_02750 11e91b912aed17862be901b2a09e1690 284 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 54 67 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_02750 11e91b912aed17862be901b2a09e1690 284 Pfam PF00809 Pterin binding enzyme 21 263 2.2E-93 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_02750 11e91b912aed17862be901b2a09e1690 284 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 277 9.0E-104 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 14 24 - T 14-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 SUPERFAMILY SSF53748 3 389 1.41E-142 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 4 389 37.644 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PIRSF PIRSF000724 1 389 6.5E-139 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 Gene3D G3DSA:3.40.50.1260 170 379 1.6E-152 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PRINTS PR00477 Phosphoglycerate kinase family signature 191 210 5.5E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 5.5E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PRINTS PR00477 Phosphoglycerate kinase family signature 30 52 5.5E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PRINTS PR00477 Phosphoglycerate kinase family signature 342 353 5.5E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 5.5E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PRINTS PR00477 Phosphoglycerate kinase family signature 168 190 5.5E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PRINTS PR00477 Phosphoglycerate kinase family signature 365 382 5.5E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PRINTS PR00477 Phosphoglycerate kinase family signature 9 25 5.5E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 PRINTS PR00477 Phosphoglycerate kinase family signature 309 334 5.5E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 Gene3D G3DSA:3.40.50.1260 7 387 1.6E-152 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06165 aa83e5d1414534d4fa5347b4cd7c671a 389 Pfam PF00162 Phosphoglycerate kinase 6 379 3.1E-147 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_06705 0237b9c874f1731004ed4aaca1f74224 339 Gene3D G3DSA:1.20.1440.130 6 168 2.8E-8 T 14-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 HL41_06705 0237b9c874f1731004ed4aaca1f74224 339 SUPERFAMILY SSF52833 181 253 1.25E-6 T 14-10-2018 IPR036249 Thioredoxin-like superfamily HL41_03535 bc78107b99e43508f88b1cfa0fe5a30a 67 Gene3D G3DSA:2.20.28.30 1 48 3.4E-5 T 14-10-2018 HL41_03535 bc78107b99e43508f88b1cfa0fe5a30a 67 Pfam PF09723 Zinc ribbon domain 1 42 5.0E-15 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_03535 bc78107b99e43508f88b1cfa0fe5a30a 67 SMART SM00834 1 43 6.6E-15 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_03535 bc78107b99e43508f88b1cfa0fe5a30a 67 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 51 2.7E-16 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_02670 3c964125bc6071a38d01bb35bfec0f75 215 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 7 202 2.0E-58 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 HL41_02670 3c964125bc6071a38d01bb35bfec0f75 215 Gene3D G3DSA:3.90.950.10 2 206 5.8E-77 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HL41_02670 3c964125bc6071a38d01bb35bfec0f75 215 Hamap MF_01405 dITP/XTP pyrophosphatase. 5 204 48.397 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 HL41_02670 3c964125bc6071a38d01bb35bfec0f75 215 SUPERFAMILY SSF52972 6 203 4.36E-67 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HL41_02670 3c964125bc6071a38d01bb35bfec0f75 215 Pfam PF01725 Ham1 family 7 200 7.0E-59 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 HL41_04930 b6601464ba9b471c1009ca72959d95d4 338 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 6 337 1.8E-106 T 14-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme HL41_04930 b6601464ba9b471c1009ca72959d95d4 338 PIRSF PIRSF004869 2 313 2.4E-108 T 14-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted HL41_04930 b6601464ba9b471c1009ca72959d95d4 338 Pfam PF04055 Radical SAM superfamily 78 234 1.9E-23 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_04930 b6601464ba9b471c1009ca72959d95d4 338 Gene3D G3DSA:3.20.20.70 65 286 1.5E-39 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_04930 b6601464ba9b471c1009ca72959d95d4 338 SUPERFAMILY SSF102114 39 314 3.27E-36 T 14-10-2018 HL41_04930 b6601464ba9b471c1009ca72959d95d4 338 SMART SM00729 72 278 0.0034 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 SUPERFAMILY SSF51206 6 129 7.07E-30 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 Pfam PF03445 Putative nucleotidyltransferase DUF294 304 416 1.2E-9 T 14-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 SMART SM00100 13 126 3.2E-12 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 SMART SM00116 155 201 0.064 T 14-10-2018 IPR000644 CBS domain HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 SMART SM00116 219 266 1.1E-6 T 14-10-2018 IPR000644 CBS domain HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 Gene3D G3DSA:3.10.580.10 144 305 6.8E-26 T 14-10-2018 HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 SUPERFAMILY SSF54631 143 263 5.68E-22 T 14-10-2018 HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 Pfam PF00027 Cyclic nucleotide-binding domain 32 114 1.2E-17 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 456 596 5.8E-37 T 14-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 Pfam PF00571 CBS domain 152 201 5.3E-5 T 14-10-2018 IPR000644 CBS domain HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 Pfam PF00571 CBS domain 216 263 2.6E-7 T 14-10-2018 IPR000644 CBS domain HL41_08480 f40c2c463cc9b9b9568880b6255a71b9 604 Gene3D G3DSA:2.60.120.10 2 141 8.9E-29 T 14-10-2018 IPR014710 RmlC-like jelly roll fold HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 1.2E-28 T 14-10-2018 IPR000362 Fumarate lyase family HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 1.2E-28 T 14-10-2018 IPR000362 Fumarate lyase family HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 1.2E-28 T 14-10-2018 IPR000362 Fumarate lyase family HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 1.2E-28 T 14-10-2018 IPR000362 Fumarate lyase family HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 Pfam PF10415 Fumarase C C-terminus 406 457 2.7E-15 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 Gene3D G3DSA:1.10.40.30 405 456 6.6E-14 T 14-10-2018 HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 Pfam PF00206 Lyase 12 334 7.2E-91 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 ProSitePatterns PS00163 Fumarate lyases signature. 314 323 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 SUPERFAMILY SSF48557 2 457 3.77E-130 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 Gene3D G3DSA:1.10.275.10 3 136 1.6E-52 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal HL41_08435 4c60d4399982186a3384fdfa1605bc16 480 Gene3D G3DSA:1.20.200.10 137 404 1.3E-106 T 14-10-2018 HL41_02430 ed47561cd8e8e1b1ce9b0f1a152f5103 311 SMART SM00470 8 98 5.8E-5 T 14-10-2018 IPR003115 ParB/Sulfiredoxin HL41_02430 ed47561cd8e8e1b1ce9b0f1a152f5103 311 Gene3D G3DSA:3.90.1530.30 28 82 8.4E-8 T 14-10-2018 HL41_02430 ed47561cd8e8e1b1ce9b0f1a152f5103 311 SUPERFAMILY SSF110849 33 118 1.74E-11 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily HL41_02430 ed47561cd8e8e1b1ce9b0f1a152f5103 311 Pfam PF02195 ParB-like nuclease domain 33 97 1.5E-7 T 14-10-2018 IPR003115 ParB/Sulfiredoxin HL41_03875 b21ad394544a99e77cf999e5c0492252 401 Pfam PF00872 Transposase, Mutator family 6 357 7.2E-65 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_06765 57896d9561c3f7e0d553e7585788928a 267 Hamap MF_00361 NAD kinase [nadK]. 12 267 28.199 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HL41_06765 57896d9561c3f7e0d553e7585788928a 267 Pfam PF01513 ATP-NAD kinase 36 249 5.5E-46 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HL41_06765 57896d9561c3f7e0d553e7585788928a 267 SUPERFAMILY SSF111331 34 267 9.94E-68 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily HL41_06765 57896d9561c3f7e0d553e7585788928a 267 Gene3D G3DSA:2.60.200.30 109 244 1.4E-68 T 14-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HL41_06765 57896d9561c3f7e0d553e7585788928a 267 Gene3D G3DSA:3.40.50.10330 41 267 1.4E-68 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 HL41_06895 54e5e6e80552808895bad4f3cefeb658 76 SMART SM00530 19 73 0.0015 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HL41_06895 54e5e6e80552808895bad4f3cefeb658 76 SUPERFAMILY SSF47413 12 74 1.1E-7 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 HL41_06895 54e5e6e80552808895bad4f3cefeb658 76 Gene3D G3DSA:1.10.260.40 5 75 8.2E-6 T 14-10-2018 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 359 1.7E-167 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 Pfam PF00472 RF-1 domain 215 325 4.3E-44 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 232 248 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 Gene3D G3DSA:3.30.160.20 215 301 1.9E-106 T 14-10-2018 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 Pfam PF03462 PCRF domain 15 208 3.5E-76 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 Gene3D G3DSA:3.30.70.1660 116 346 1.9E-106 T 14-10-2018 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 SMART SM00937 69 183 3.4E-65 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 SUPERFAMILY SSF75620 14 357 2.75E-142 T 14-10-2018 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 7 361 40.858 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HL41_08065 3c4218799c992041e7c5565710eeef2e 367 Gene3D G3DSA:1.20.58.410 3 99 1.1E-8 T 14-10-2018 HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 Gene3D G3DSA:3.30.479.30 46 177 1.3E-55 T 14-10-2018 HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 PRINTS PR00721 Stomatin signature 127 150 3.2E-69 T 14-10-2018 IPR001972 Stomatin family GO:0016020 HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 PRINTS PR00721 Stomatin signature 25 47 3.2E-69 T 14-10-2018 IPR001972 Stomatin family GO:0016020 HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 PRINTS PR00721 Stomatin signature 107 124 3.2E-69 T 14-10-2018 IPR001972 Stomatin family GO:0016020 HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 PRINTS PR00721 Stomatin signature 72 93 3.2E-69 T 14-10-2018 IPR001972 Stomatin family GO:0016020 HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 PRINTS PR00721 Stomatin signature 170 191 3.2E-69 T 14-10-2018 IPR001972 Stomatin family GO:0016020 HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 PRINTS PR00721 Stomatin signature 195 218 3.2E-69 T 14-10-2018 IPR001972 Stomatin family GO:0016020 HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 PRINTS PR00721 Stomatin signature 151 169 3.2E-69 T 14-10-2018 IPR001972 Stomatin family GO:0016020 HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 Pfam PF01145 SPFH domain / Band 7 family 22 191 2.1E-37 T 14-10-2018 IPR001107 Band 7 domain HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 SUPERFAMILY SSF117892 49 182 2.35E-47 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 SMART SM00244 18 175 4.8E-70 T 14-10-2018 IPR001107 Band 7 domain HL41_05645 92c21e80daa474fec5fbcb18ccb11a57 248 ProSitePatterns PS01270 Band 7 protein family signature. 131 159 - T 14-10-2018 IPR018080 Band 7/stomatin-like, conserved site HL41_03810 1edd8e0f4fe535ef2ae22c9a5bddf169 997 Pfam PF12705 PD-(D/E)XK nuclease superfamily 682 991 3.1E-20 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type HL41_03810 1edd8e0f4fe535ef2ae22c9a5bddf169 997 Gene3D G3DSA:3.40.50.300 529 700 9.7E-6 T 14-10-2018 HL41_03810 1edd8e0f4fe535ef2ae22c9a5bddf169 997 SUPERFAMILY SSF52540 262 648 1.05E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04820 f788ceb48620d06284f74199656966cf 320 Gene3D G3DSA:3.90.1310.30 36 188 2.3E-5 T 14-10-2018 HL41_04820 f788ceb48620d06284f74199656966cf 320 SUPERFAMILY SSF56519 40 157 1.7E-8 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 HL41_02175 457ec0befd5ff60cdbfbe38e6f4b4bc4 277 Gene3D G3DSA:3.40.1010.10 24 163 9.7E-30 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 HL41_02175 457ec0befd5ff60cdbfbe38e6f4b4bc4 277 SUPERFAMILY SSF53790 25 273 5.76E-43 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 HL41_02175 457ec0befd5ff60cdbfbe38e6f4b4bc4 277 Gene3D G3DSA:3.30.950.10 164 274 3.6E-13 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 HL41_02175 457ec0befd5ff60cdbfbe38e6f4b4bc4 277 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 27 252 2.6E-40 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 HL41_03820 ac30f96d4444921df3f6cdf930ec46a4 355 ProSitePatterns PS00770 Aminotransferases class-IV signature. 231 260 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 HL41_03820 ac30f96d4444921df3f6cdf930ec46a4 355 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 42 352 9.2E-122 T 14-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 HL41_03820 ac30f96d4444921df3f6cdf930ec46a4 355 Gene3D G3DSA:3.30.470.10 23 350 9.2E-141 T 14-10-2018 HL41_03820 ac30f96d4444921df3f6cdf930ec46a4 355 Pfam PF01063 Amino-transferase class IV 68 311 1.1E-36 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 HL41_03820 ac30f96d4444921df3f6cdf930ec46a4 355 PIRSF PIRSF006468 1 355 9.7E-134 T 14-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 HL41_03820 ac30f96d4444921df3f6cdf930ec46a4 355 Gene3D G3DSA:3.20.10.10 169 337 9.2E-141 T 14-10-2018 HL41_03820 ac30f96d4444921df3f6cdf930ec46a4 355 SUPERFAMILY SSF56752 9 351 1.12E-117 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 HL41_04535 def4ec31d6089848cce4ba7167667170 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 228 3.1E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HL41_04535 def4ec31d6089848cce4ba7167667170 234 Gene3D G3DSA:1.10.3720.10 2 232 2.2E-35 T 14-10-2018 IPR035906 MetI-like superfamily HL41_04535 def4ec31d6089848cce4ba7167667170 234 SUPERFAMILY SSF161098 12 226 1.57E-35 T 14-10-2018 IPR035906 MetI-like superfamily HL41_08640 13a489c489101ac95ddb568fed27d7dd 319 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 168 179 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08640 13a489c489101ac95ddb568fed27d7dd 319 Gene3D G3DSA:3.30.70.20 60 263 1.0E-69 T 14-10-2018 HL41_08640 13a489c489101ac95ddb568fed27d7dd 319 SUPERFAMILY SSF54862 61 312 7.85E-62 T 14-10-2018 HL41_08640 13a489c489101ac95ddb568fed27d7dd 319 Gene3D G3DSA:3.30.70.20 58 200 1.0E-69 T 14-10-2018 HL41_08640 13a489c489101ac95ddb568fed27d7dd 319 Pfam PF13247 4Fe-4S dicluster domain 129 227 1.1E-22 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_04175 a6b90aefe0362f1466a07dfdfd0a8e24 219 PRINTS PR00114 Serine/threonine phosphatase family signature 6 33 3.9E-5 T 14-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HL41_04175 a6b90aefe0362f1466a07dfdfd0a8e24 219 PRINTS PR00114 Serine/threonine phosphatase family signature 36 63 3.9E-5 T 14-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HL41_04175 a6b90aefe0362f1466a07dfdfd0a8e24 219 Gene3D G3DSA:3.60.21.10 3 219 1.2E-62 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like HL41_04175 a6b90aefe0362f1466a07dfdfd0a8e24 219 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 70 75 - T 14-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HL41_04175 a6b90aefe0362f1466a07dfdfd0a8e24 219 Pfam PF00149 Calcineurin-like phosphoesterase 5 186 4.3E-22 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HL41_04175 a6b90aefe0362f1466a07dfdfd0a8e24 219 SUPERFAMILY SSF56300 6 207 3.95E-50 T 14-10-2018 HL41_02815 52eaee76f61df6c67ef83e9e4eff680e 465 SMART SM00304 136 188 0.0023 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HL41_02815 52eaee76f61df6c67ef83e9e4eff680e 465 SMART SM00304 391 444 75.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 HL41_02815 52eaee76f61df6c67ef83e9e4eff680e 465 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 250 429 6.2E-39 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02815 52eaee76f61df6c67ef83e9e4eff680e 465 SMART SM00283 203 464 4.5E-55 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02815 52eaee76f61df6c67ef83e9e4eff680e 465 Pfam PF08269 Cache domain 1 110 6.0E-19 T 14-10-2018 IPR004010 Double Cache domain 2 HL41_02815 52eaee76f61df6c67ef83e9e4eff680e 465 SUPERFAMILY SSF58104 157 465 4.19E-65 T 14-10-2018 HL41_02815 52eaee76f61df6c67ef83e9e4eff680e 465 Gene3D G3DSA:3.30.450.20 1 109 1.1E-29 T 14-10-2018 HL41_02815 52eaee76f61df6c67ef83e9e4eff680e 465 Gene3D G3DSA:1.10.287.950 135 465 5.6E-67 T 14-10-2018 HL41_05860 e5713c720cb748ed4ae3cfe6b643be1e 202 SUPERFAMILY SSF48452 42 190 5.22E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_05860 e5713c720cb748ed4ae3cfe6b643be1e 202 Gene3D G3DSA:1.25.40.10 18 197 9.8E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_05860 e5713c720cb748ed4ae3cfe6b643be1e 202 SMART SM00028 120 153 10.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05860 e5713c720cb748ed4ae3cfe6b643be1e 202 SMART SM00028 155 188 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_05860 e5713c720cb748ed4ae3cfe6b643be1e 202 Pfam PF09976 Tetratricopeptide repeat-like domain 16 202 3.8E-11 T 14-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 HL41_08080 27ac00a756b428fa879f7f5ab05ddf74 394 Pfam PF13646 HEAT repeats 277 344 7.2E-9 T 14-10-2018 HL41_08080 27ac00a756b428fa879f7f5ab05ddf74 394 SMART SM00567 E-Z type HEAT repeats 286 315 40.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 HL41_08080 27ac00a756b428fa879f7f5ab05ddf74 394 SMART SM00567 E-Z type HEAT repeats 117 146 0.64 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 HL41_08080 27ac00a756b428fa879f7f5ab05ddf74 394 SMART SM00567 E-Z type HEAT repeats 317 346 860.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 HL41_08080 27ac00a756b428fa879f7f5ab05ddf74 394 Gene3D G3DSA:1.25.10.10 231 366 1.6E-10 T 14-10-2018 IPR011989 Armadillo-like helical HL41_08080 27ac00a756b428fa879f7f5ab05ddf74 394 SUPERFAMILY SSF48371 39 343 1.26E-18 T 14-10-2018 IPR016024 Armadillo-type fold HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 Pfam PF00176 SNF2 family N-terminal domain 339 472 2.8E-7 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 Gene3D G3DSA:3.40.50.300 244 405 2.5E-16 T 14-10-2018 HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 SUPERFAMILY SSF52540 205 462 3.49E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 SUPERFAMILY SSF56024 115 202 3.05E-6 T 14-10-2018 HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 SUPERFAMILY SSF52540 347 816 4.71E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 SMART SM00490 681 770 3.2E-18 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 SMART SM00487 251 419 8.8E-7 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 Gene3D G3DSA:3.40.50.300 587 804 5.7E-37 T 14-10-2018 HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 Pfam PF13091 PLD-like domain 25 196 2.9E-11 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 Pfam PF00271 Helicase conserved C-terminal domain 655 769 1.4E-21 T 14-10-2018 IPR001650 Helicase, C-terminal HL41_03840 f0d516058427bbcf8f18d09bd3fc88ab 1072 Gene3D G3DSA:3.30.870.10 9 219 1.6E-26 T 14-10-2018 HL41_01310 084db71ae73715ef8d4ac07cf0be8500 114 SUPERFAMILY SSF54523 5 93 7.22E-12 T 14-10-2018 HL41_01310 084db71ae73715ef8d4ac07cf0be8500 114 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 24 1.5E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_01310 084db71ae73715ef8d4ac07cf0be8500 114 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 1.2E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_01310 084db71ae73715ef8d4ac07cf0be8500 114 Gene3D G3DSA:3.30.700.10 5 111 6.6E-13 T 14-10-2018 HL41_04350 220f8e52e534a67de1c5f68c91ac5d08 150 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 30.95 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 HL41_04350 220f8e52e534a67de1c5f68c91ac5d08 150 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 9.2E-53 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 HL41_04350 220f8e52e534a67de1c5f68c91ac5d08 150 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 1.2E-51 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 HL41_04350 220f8e52e534a67de1c5f68c91ac5d08 150 Gene3D G3DSA:3.50.80.10 1 147 2.1E-56 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily HL41_04350 220f8e52e534a67de1c5f68c91ac5d08 150 SUPERFAMILY SSF69500 1 144 4.19E-51 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily HL41_03715 a58d769fb61fc79cadb72f60d3ce3a56 390 SUPERFAMILY SSF48695 228 382 2.92E-13 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_03715 a58d769fb61fc79cadb72f60d3ce3a56 390 Gene3D G3DSA:3.90.10.10 167 286 2.7E-5 T 14-10-2018 HL41_03715 a58d769fb61fc79cadb72f60d3ce3a56 390 SUPERFAMILY SSF48695 36 266 5.8E-25 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_03715 a58d769fb61fc79cadb72f60d3ce3a56 390 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 249 284 2.5E-4 T 14-10-2018 IPR010177 Doubled CXXCH motif HL41_03715 a58d769fb61fc79cadb72f60d3ce3a56 390 Gene3D G3DSA:1.10.3820.10 6 149 4.1E-6 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily HL41_06075 f4df970b8124c4044f255ccc66e6dfb2 467 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 390 463 3.9E-20 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HL41_06075 f4df970b8124c4044f255ccc66e6dfb2 467 Pfam PF07559 Flagellar basal body protein FlaE 197 347 9.3E-6 T 14-10-2018 IPR011491 Flagellar hook protein FlgE HL41_06075 f4df970b8124c4044f255ccc66e6dfb2 467 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site HL41_06075 f4df970b8124c4044f255ccc66e6dfb2 467 SUPERFAMILY SSF117143 83 428 3.79E-41 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like HL41_06075 f4df970b8124c4044f255ccc66e6dfb2 467 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 6 449 2.2E-63 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G HL41_06075 f4df970b8124c4044f255ccc66e6dfb2 467 Pfam PF00460 Flagella basal body rod protein 8 37 1.3E-4 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HL41_02180 2e0232a993e96fd9f7545015f47b9329 442 Gene3D G3DSA:1.20.1740.10 11 441 1.3E-92 T 14-10-2018 HL41_02180 2e0232a993e96fd9f7545015f47b9329 442 PIRSF PIRSF006060 4 435 6.2E-74 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HL41_02180 2e0232a993e96fd9f7545015f47b9329 442 Pfam PF13520 Amino acid permease 16 408 5.9E-54 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HL41_04780 a1237c8a48b23ac112a923859ac98ab3 242 Pfam PF08478 POTRA domain, FtsQ-type 38 104 1.3E-13 T 14-10-2018 IPR013685 POTRA domain, FtsQ-type HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 3.0E-12 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 3.0E-12 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 3.0E-12 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 3.0E-12 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 4 59 3.8E-22 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 14-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.969 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 Pfam PF01165 Ribosomal protein S21 4 56 2.7E-21 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 43 1.0E-4 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04235 70ca3b23bfab448a66ff3e6b56591f9a 70 Gene3D G3DSA:1.20.5.1150 16 54 1.4E-13 T 14-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04970 fda3dd78010772024c88443421b1e652 274 Pfam PF06230 Protein of unknown function (DUF1009) 59 265 3.0E-76 T 14-10-2018 IPR010415 Protein of unknown function DUF1009 KEGG: 00540+3.6.1.54 HL41_04970 fda3dd78010772024c88443421b1e652 274 Gene3D G3DSA:3.40.140.80 132 271 2.9E-51 T 14-10-2018 HL41_04970 fda3dd78010772024c88443421b1e652 274 Gene3D G3DSA:3.40.50.20 2 131 4.1E-31 T 14-10-2018 HL41_08935 2388dd7e6b4b8a6b86d708552f0e44f7 398 SUPERFAMILY SSF103501 231 386 1.11E-16 T 14-10-2018 IPR036197 NarG-like superfamily HL41_08935 2388dd7e6b4b8a6b86d708552f0e44f7 398 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 29 40 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08935 2388dd7e6b4b8a6b86d708552f0e44f7 398 Gene3D G3DSA:1.10.1060.10 6 105 6.4E-6 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_08935 2388dd7e6b4b8a6b86d708552f0e44f7 398 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 73 84 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_08935 2388dd7e6b4b8a6b86d708552f0e44f7 398 SUPERFAMILY SSF46548 24 100 4.71E-14 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_08935 2388dd7e6b4b8a6b86d708552f0e44f7 398 Pfam PF13534 4Fe-4S dicluster domain 28 86 7.0E-7 T 14-10-2018 HL41_01820 6e2db77e47b8bc591085ccda621c865f 256 SUPERFAMILY SSF51905 2 248 2.49E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_01820 6e2db77e47b8bc591085ccda621c865f 256 PRINTS PR00419 Adrenodoxin reductase family signature 24 46 2.3E-6 T 14-10-2018 HL41_01820 6e2db77e47b8bc591085ccda621c865f 256 PRINTS PR00419 Adrenodoxin reductase family signature 47 60 2.3E-6 T 14-10-2018 HL41_01820 6e2db77e47b8bc591085ccda621c865f 256 Pfam PF01946 Thi4 family 7 234 2.5E-68 T 14-10-2018 HL41_01820 6e2db77e47b8bc591085ccda621c865f 256 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 2 252 9.5E-91 T 14-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family HL41_01820 6e2db77e47b8bc591085ccda621c865f 256 Gene3D G3DSA:3.50.50.60 1 256 6.8E-87 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_01820 6e2db77e47b8bc591085ccda621c865f 256 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 1 253 39.662 T 14-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic HL41_06520 6f59b4d0814605000b8fa91f6a0e1863 250 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 241 2.7E-68 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 HL41_06520 6f59b4d0814605000b8fa91f6a0e1863 250 Gene3D G3DSA:3.40.50.150 69 250 1.6E-73 T 14-10-2018 HL41_06520 6f59b4d0814605000b8fa91f6a0e1863 250 Gene3D G3DSA:3.10.290.10 2 68 3.4E-18 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 HL41_06520 6f59b4d0814605000b8fa91f6a0e1863 250 PIRSF PIRSF005578 1 250 4.0E-94 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 HL41_06520 6f59b4d0814605000b8fa91f6a0e1863 250 Pfam PF01728 FtsJ-like methyltransferase 66 247 1.9E-18 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 HL41_06520 6f59b4d0814605000b8fa91f6a0e1863 250 SUPERFAMILY SSF53335 28 246 3.02E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_06520 6f59b4d0814605000b8fa91f6a0e1863 250 Pfam PF01479 S4 domain 7 33 5.7E-6 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 Pfam PF01926 50S ribosome-binding GTPase 230 340 6.3E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 227 379 6.4E-29 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 SUPERFAMILY SSF52540 83 382 1.54E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 Gene3D G3DSA:3.40.50.300 227 393 3.7E-108 T 14-10-2018 HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 15 466 1.7E-131 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 Pfam PF10396 GTP-binding protein TrmE N-terminus 10 129 1.4E-39 T 14-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 9 466 33.717 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 Gene3D G3DSA:1.20.120.430 130 466 3.7E-108 T 14-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 Gene3D G3DSA:3.30.1360.120 4 129 7.0E-47 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 HL41_04085 97dc3edc25fe189e8232d30dfb1e6459 466 Pfam PF12631 MnmE helical domain 132 463 4.3E-52 T 14-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 HL41_06295 422c0c2291e3e24f6a6ff27b92e7f4f8 302 SUPERFAMILY SSF53448 5 281 3.13E-47 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_06295 422c0c2291e3e24f6a6ff27b92e7f4f8 302 Pfam PF00535 Glycosyl transferase family 2 9 189 5.9E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HL41_06295 422c0c2291e3e24f6a6ff27b92e7f4f8 302 Gene3D G3DSA:3.90.550.10 1 233 2.4E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 1 159 1.5E-49 T 14-10-2018 IPR023635 Peptide deformylase HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 Hamap MF_00163 Peptide deformylase [def]. 1 161 27.716 T 14-10-2018 IPR023635 Peptide deformylase HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 PIRSF PIRSF004749 1 165 3.3E-52 T 14-10-2018 IPR023635 Peptide deformylase HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 SUPERFAMILY SSF56420 2 161 7.59E-58 T 14-10-2018 IPR036821 Peptide deformylase superfamily HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 PRINTS PR01576 Peptide deformylase signature 100 118 2.6E-36 T 14-10-2018 IPR023635 Peptide deformylase HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 PRINTS PR01576 Peptide deformylase signature 88 99 2.6E-36 T 14-10-2018 IPR023635 Peptide deformylase HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 PRINTS PR01576 Peptide deformylase signature 30 59 2.6E-36 T 14-10-2018 IPR023635 Peptide deformylase HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 PRINTS PR01576 Peptide deformylase signature 119 148 2.6E-36 T 14-10-2018 IPR023635 Peptide deformylase HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 Pfam PF01327 Polypeptide deformylase 2 151 1.5E-52 T 14-10-2018 IPR023635 Peptide deformylase HL41_01530 fd3a874343f7d62676cebe41df5c1f76 165 Gene3D G3DSA:3.90.45.10 1 165 2.0E-59 T 14-10-2018 IPR036821 Peptide deformylase superfamily HL41_05525 20e412b3fcaf1f8660ba2a3d1083d8f4 175 SUPERFAMILY SSF55469 10 172 2.88E-52 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HL41_05525 20e412b3fcaf1f8660ba2a3d1083d8f4 175 Pfam PF00881 Nitroreductase family 71 154 2.3E-16 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HL41_05525 20e412b3fcaf1f8660ba2a3d1083d8f4 175 Pfam PF00881 Nitroreductase family 15 69 7.4E-15 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HL41_05525 20e412b3fcaf1f8660ba2a3d1083d8f4 175 Gene3D G3DSA:3.40.109.10 5 175 8.8E-55 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HL41_06660 b0b282615d4145d5eca64e1e4eb41ff4 403 Pfam PF00482 Type II secretion system (T2SS), protein F 66 189 3.6E-33 T 14-10-2018 IPR018076 Type II secretion system F domain HL41_06660 b0b282615d4145d5eca64e1e4eb41ff4 403 Pfam PF00482 Type II secretion system (T2SS), protein F 270 391 1.9E-24 T 14-10-2018 IPR018076 Type II secretion system F domain HL41_06660 b0b282615d4145d5eca64e1e4eb41ff4 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 380 399 5.4E-18 T 14-10-2018 IPR003004 GspF/PilC family HL41_06660 b0b282615d4145d5eca64e1e4eb41ff4 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 364 378 5.4E-18 T 14-10-2018 IPR003004 GspF/PilC family HL41_06660 b0b282615d4145d5eca64e1e4eb41ff4 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 62 74 5.4E-18 T 14-10-2018 IPR003004 GspF/PilC family HL41_06660 b0b282615d4145d5eca64e1e4eb41ff4 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 161 189 5.4E-18 T 14-10-2018 IPR003004 GspF/PilC family HL41_06660 b0b282615d4145d5eca64e1e4eb41ff4 403 Gene3D G3DSA:1.20.81.30 252 363 1.1E-24 T 14-10-2018 HL41_06660 b0b282615d4145d5eca64e1e4eb41ff4 403 Gene3D G3DSA:1.20.81.30 51 168 7.4E-35 T 14-10-2018 HL41_02055 29a03d386ab59f5260f0fe902ab7314e 155 Gene3D G3DSA:3.30.300.70 2 82 5.9E-28 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily HL41_02055 29a03d386ab59f5260f0fe902ab7314e 155 Pfam PF17384 RimP C-terminal SH3 domain 88 153 1.6E-19 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal HL41_02055 29a03d386ab59f5260f0fe902ab7314e 155 SUPERFAMILY SSF75420 4 85 6.02E-23 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily HL41_02055 29a03d386ab59f5260f0fe902ab7314e 155 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 8 153 24.951 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 HL41_02055 29a03d386ab59f5260f0fe902ab7314e 155 Pfam PF02576 RimP N-terminal domain 14 85 2.5E-25 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal HL41_02055 29a03d386ab59f5260f0fe902ab7314e 155 SUPERFAMILY SSF74942 86 153 3.53E-17 T 14-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily HL41_08200 758b5d6bb771a968f2133fc275f0ee05 397 Pfam PF00202 Aminotransferase class-III 14 392 2.8E-124 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HL41_08200 758b5d6bb771a968f2133fc275f0ee05 397 SUPERFAMILY SSF53383 11 394 4.59E-128 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase HL41_08200 758b5d6bb771a968f2133fc275f0ee05 397 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 395 68.691 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HL41_08200 758b5d6bb771a968f2133fc275f0ee05 397 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 218 255 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HL41_08200 758b5d6bb771a968f2133fc275f0ee05 397 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 13 392 1.6E-150 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HL41_08200 758b5d6bb771a968f2133fc275f0ee05 397 Gene3D G3DSA:3.90.1150.10 20 384 7.6E-149 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 HL41_08200 758b5d6bb771a968f2133fc275f0ee05 397 Gene3D G3DSA:3.40.640.10 55 300 7.6E-149 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 HL41_08200 758b5d6bb771a968f2133fc275f0ee05 397 PIRSF PIRSF000521 168 395 5.1E-41 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HL41_08200 758b5d6bb771a968f2133fc275f0ee05 397 PIRSF PIRSF000521 21 152 7.3E-9 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HL41_07685 2c50e2002f8d7488818b051c668f7a62 181 SUPERFAMILY SSF111384 28 171 7.72E-26 T 14-10-2018 HL41_07685 2c50e2002f8d7488818b051c668f7a62 181 SMART SM00935 14 171 4.5E-33 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 HL41_07685 2c50e2002f8d7488818b051c668f7a62 181 Pfam PF03938 Outer membrane protein (OmpH-like) 12 169 8.5E-29 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 HL41_07685 2c50e2002f8d7488818b051c668f7a62 181 Gene3D G3DSA:3.30.910.20 16 181 1.9E-31 T 14-10-2018 IPR024930 Skp domain superfamily HL41_09195 c71ffb84f843be885c3238d6e20ed577 232 SUPERFAMILY SSF54862 110 216 5.59E-21 T 14-10-2018 HL41_09195 c71ffb84f843be885c3238d6e20ed577 232 Pfam PF12838 4Fe-4S dicluster domain 159 207 1.5E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_09195 c71ffb84f843be885c3238d6e20ed577 232 SUPERFAMILY SSF51905 18 158 4.63E-7 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_09195 c71ffb84f843be885c3238d6e20ed577 232 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 160 171 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_09195 c71ffb84f843be885c3238d6e20ed577 232 Gene3D G3DSA:3.30.70.20 183 212 6.5E-6 T 14-10-2018 HL41_09195 c71ffb84f843be885c3238d6e20ed577 232 Gene3D G3DSA:3.30.70.20 132 182 3.0E-6 T 14-10-2018 HL41_09195 c71ffb84f843be885c3238d6e20ed577 232 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 193 204 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07610 05183fb88ca8077220b1115ada891710 263 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 142 254 2.1E-32 T 14-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 HL41_07610 05183fb88ca8077220b1115ada891710 263 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 5 259 36.785 T 14-10-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 HL41_07610 05183fb88ca8077220b1115ada891710 263 Gene3D G3DSA:3.10.270.10 3 258 1.0E-97 T 14-10-2018 HL41_07610 05183fb88ca8077220b1115ada891710 263 Pfam PF02649 Type I GTP cyclohydrolase folE2 5 254 1.6E-94 T 14-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 Pfam PF02954 Bacterial regulatory protein, Fis family 407 447 1.4E-17 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 Gene3D G3DSA:3.40.50.300 145 309 1.2E-59 T 14-10-2018 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 164 177 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 SMART SM00382 160 302 1.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 Gene3D G3DSA:1.10.8.60 310 376 2.4E-19 T 14-10-2018 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 SUPERFAMILY SSF46689 353 449 2.96E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 SUPERFAMILY SSF52172 4 185 4.7E-35 T 14-10-2018 IPR011006 CheY-like superfamily HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 SMART SM00448 5 117 1.7E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 413 430 2.2E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 430 450 2.2E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 SUPERFAMILY SSF52540 147 378 2.1E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 Pfam PF00158 Sigma-54 interaction domain 147 305 3.7E-62 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 Pfam PF00072 Response regulator receiver domain 7 111 2.6E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 Gene3D G3DSA:3.40.50.2300 1 140 1.0E-30 T 14-10-2018 HL41_04680 40a2ed07bff451fb1ce0d109a183452a 451 Gene3D G3DSA:1.10.10.60 385 451 7.8E-19 T 14-10-2018 HL41_00320 969874cfbbeca6a5317b61125c483e67 493 PIRSF PIRSF006677 1 493 6.7E-181 T 14-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HL41_00320 969874cfbbeca6a5317b61125c483e67 493 Hamap MF_01904 Phosphoenolpyruvate carboxylase [ppcA]. 2 493 38.424 T 14-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HL41_00320 969874cfbbeca6a5317b61125c483e67 493 TIGRFAM TIGR02751 PEPCase_arch: phosphoenolpyruvate carboxylase 3 493 8.3E-181 T 14-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HL41_00320 969874cfbbeca6a5317b61125c483e67 493 SUPERFAMILY SSF51621 102 423 6.91E-38 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 HL41_00320 969874cfbbeca6a5317b61125c483e67 493 Pfam PF14010 Phosphoenolpyruvate carboxylase 3 493 2.7E-182 T 14-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HL41_04465 c931c7b92c62d9a0bb66e5be6cd30a42 185 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_04465 c931c7b92c62d9a0bb66e5be6cd30a42 185 Pfam PF13247 4Fe-4S dicluster domain 51 144 5.6E-23 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_04465 c931c7b92c62d9a0bb66e5be6cd30a42 185 Gene3D G3DSA:3.30.70.20 64 115 1.2E-65 T 14-10-2018 HL41_04465 c931c7b92c62d9a0bb66e5be6cd30a42 185 Pfam PF00037 4Fe-4S binding domain 7 23 8.7E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_04465 c931c7b92c62d9a0bb66e5be6cd30a42 185 Gene3D G3DSA:3.30.70.20 4 177 1.2E-65 T 14-10-2018 HL41_04465 c931c7b92c62d9a0bb66e5be6cd30a42 185 SUPERFAMILY SSF54862 1 177 7.33E-66 T 14-10-2018 HL41_06375 8b887f285681c0660be3fe9cb1b7825d 83 SUPERFAMILY SSF143011 4 81 5.36E-17 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily HL41_06375 8b887f285681c0660be3fe9cb1b7825d 83 Gene3D G3DSA:3.30.2310.20 4 83 5.7E-23 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily HL41_06375 8b887f285681c0660be3fe9cb1b7825d 83 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 80 2.0E-8 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family HL41_07180 12ea272a6584a6548346a8c69446298e 368 Gene3D G3DSA:3.40.50.720 5 361 2.3E-118 T 14-10-2018 HL41_07180 12ea272a6584a6548346a8c69446298e 368 PIRSF PIRSF015578 1 365 1.8E-89 T 14-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 HL41_07180 12ea272a6584a6548346a8c69446298e 368 Gene3D G3DSA:3.30.360.10 199 308 2.3E-118 T 14-10-2018 HL41_07180 12ea272a6584a6548346a8c69446298e 368 Pfam PF01658 Myo-inositol-1-phosphate synthase 200 308 1.1E-30 T 14-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 HL41_07180 12ea272a6584a6548346a8c69446298e 368 SUPERFAMILY SSF51735 5 364 3.94E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_07180 12ea272a6584a6548346a8c69446298e 368 SUPERFAMILY SSF55347 198 308 2.75E-35 T 14-10-2018 HL41_03185 a81f2f53e6f9de91513e75450a7737e5 427 SUPERFAMILY SSF56954 6 423 1.1E-71 T 14-10-2018 HL41_03185 a81f2f53e6f9de91513e75450a7737e5 427 Gene3D G3DSA:1.20.1600.10 25 421 6.8E-72 T 14-10-2018 HL41_03185 a81f2f53e6f9de91513e75450a7737e5 427 Pfam PF02321 Outer membrane efflux protein 240 420 4.3E-34 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 HL41_03185 a81f2f53e6f9de91513e75450a7737e5 427 Pfam PF02321 Outer membrane efflux protein 30 213 1.4E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 HL41_00965 9d0ad86cbda37f18f6f7f30e64c8c911 260 Pfam PF00460 Flagella basal body rod protein 5 35 1.3E-12 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HL41_00965 9d0ad86cbda37f18f6f7f30e64c8c911 260 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 180 258 4.1E-23 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HL41_00965 9d0ad86cbda37f18f6f7f30e64c8c911 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 135 3.0E-46 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G HL41_00965 9d0ad86cbda37f18f6f7f30e64c8c911 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 142 241 1.8E-33 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G HL41_00965 9d0ad86cbda37f18f6f7f30e64c8c911 260 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 5 258 5.4E-101 T 14-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 HL41_00965 9d0ad86cbda37f18f6f7f30e64c8c911 260 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site HL41_00965 9d0ad86cbda37f18f6f7f30e64c8c911 260 SUPERFAMILY SSF117143 93 220 3.92E-36 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like HL41_04415 0d6e82036404d22af760de18c4f15e26 249 Gene3D G3DSA:3.30.1600.10 34 168 2.3E-83 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily HL41_04415 0d6e82036404d22af760de18c4f15e26 249 SUPERFAMILY SSF52467 5 247 1.73E-79 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily HL41_04415 0d6e82036404d22af760de18c4f15e26 249 Gene3D G3DSA:3.40.50.1220 19 242 2.3E-83 T 14-10-2018 HL41_04415 0d6e82036404d22af760de18c4f15e26 249 Pfam PF02146 Sir2 family 25 198 1.1E-51 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 HL41_04560 fddd69d37ce37609006e8e8477331837 713 Gene3D G3DSA:3.40.50.2000 177 366 6.1E-8 T 14-10-2018 HL41_04560 fddd69d37ce37609006e8e8477331837 713 SUPERFAMILY SSF53756 65 364 8.79E-28 T 14-10-2018 HL41_04560 fddd69d37ce37609006e8e8477331837 713 Gene3D G3DSA:3.40.50.2000 58 147 3.8E-9 T 14-10-2018 HL41_04560 fddd69d37ce37609006e8e8477331837 713 Pfam PF13489 Methyltransferase domain 471 616 3.3E-20 T 14-10-2018 HL41_04560 fddd69d37ce37609006e8e8477331837 713 Gene3D G3DSA:3.40.50.150 433 625 3.6E-32 T 14-10-2018 HL41_04560 fddd69d37ce37609006e8e8477331837 713 SUPERFAMILY SSF53335 466 626 5.47E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_05330 f5d3689e4dffa55c4ae04351fca09d69 79 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.3E-36 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HL41_05330 f5d3689e4dffa55c4ae04351fca09d69 79 Gene3D G3DSA:2.40.50.140 2 70 2.2E-35 T 14-10-2018 HL41_05330 f5d3689e4dffa55c4ae04351fca09d69 79 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 74 26.664 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HL41_05330 f5d3689e4dffa55c4ae04351fca09d69 79 Pfam PF01176 Translation initiation factor 1A / IF-1 10 70 4.0E-28 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 HL41_05330 f5d3689e4dffa55c4ae04351fca09d69 79 SUPERFAMILY SSF50249 1 70 3.18E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold HL41_03485 9cef0dd3d7a7da1664191033c0abf47a 274 Pfam PF00793 DAHP synthetase I family 3 256 8.2E-68 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 HL41_03485 9cef0dd3d7a7da1664191033c0abf47a 274 SUPERFAMILY SSF51569 3 261 6.14E-98 T 14-10-2018 HL41_03485 9cef0dd3d7a7da1664191033c0abf47a 274 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 1 261 49.485 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 HL41_03485 9cef0dd3d7a7da1664191033c0abf47a 274 Gene3D G3DSA:3.20.20.70 1 264 4.0E-100 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_03485 9cef0dd3d7a7da1664191033c0abf47a 274 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 4 259 6.3E-118 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 HL41_03120 6ac7a3ea5b430e6d894ad2e3f526bd39 93 Gene3D G3DSA:1.20.58.110 1 86 3.9E-25 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_03120 6ac7a3ea5b430e6d894ad2e3f526bd39 93 Pfam PF01649 Ribosomal protein S20 2 83 4.2E-26 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_03120 6ac7a3ea5b430e6d894ad2e3f526bd39 93 TIGRFAM TIGR00029 S20: ribosomal protein bS20 3 85 3.2E-20 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_03120 6ac7a3ea5b430e6d894ad2e3f526bd39 93 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 83 2.0E-11 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_03120 6ac7a3ea5b430e6d894ad2e3f526bd39 93 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 14.471 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_03120 6ac7a3ea5b430e6d894ad2e3f526bd39 93 SUPERFAMILY SSF46992 4 85 2.22E-25 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_03175 b5321438314c1075b5b883c39d88a69d 204 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 200 7.2E-54 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 HL41_03175 b5321438314c1075b5b883c39d88a69d 204 Pfam PF01914 MarC family integral membrane protein 4 204 9.3E-57 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 HL41_06440 d93ac7925ed7250e9c745ab26f742826 152 SUPERFAMILY SSF52402 4 145 4.35E-37 T 14-10-2018 HL41_06440 d93ac7925ed7250e9c745ab26f742826 152 PRINTS PR01438 Universal stress protein signature 105 117 2.5E-17 T 14-10-2018 IPR006015 Universal stress protein A HL41_06440 d93ac7925ed7250e9c745ab26f742826 152 PRINTS PR01438 Universal stress protein signature 123 145 2.5E-17 T 14-10-2018 IPR006015 Universal stress protein A HL41_06440 d93ac7925ed7250e9c745ab26f742826 152 PRINTS PR01438 Universal stress protein signature 4 22 2.5E-17 T 14-10-2018 IPR006015 Universal stress protein A HL41_06440 d93ac7925ed7250e9c745ab26f742826 152 Pfam PF00582 Universal stress protein family 4 143 1.5E-32 T 14-10-2018 IPR006016 UspA HL41_06440 d93ac7925ed7250e9c745ab26f742826 152 Gene3D G3DSA:3.40.50.620 1 151 3.8E-37 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_06440 d93ac7925ed7250e9c745ab26f742826 152 PIRSF PIRSF006276 2 148 1.2E-26 T 14-10-2018 IPR006015 Universal stress protein A HL41_02505 b74f8faffc6e2d9818a6a9144d164085 79 PIRSF PIRSF037031 3 79 8.8E-30 T 14-10-2018 IPR005243 Redox-active disulphide protein 2 HL41_02505 b74f8faffc6e2d9818a6a9144d164085 79 SUPERFAMILY SSF52833 4 77 8.5E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily HL41_02505 b74f8faffc6e2d9818a6a9144d164085 79 Gene3D G3DSA:3.40.30.10 4 78 1.5E-24 T 14-10-2018 HL41_02505 b74f8faffc6e2d9818a6a9144d164085 79 Pfam PF13192 Thioredoxin domain 5 77 8.5E-22 T 14-10-2018 IPR012336 Thioredoxin-like fold HL41_02505 b74f8faffc6e2d9818a6a9144d164085 79 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 5 79 2.0E-25 T 14-10-2018 IPR005243 Redox-active disulphide protein 2 HL41_06505 c6a4de85e3e727ae09234ddd3ed6811d 210 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 11 209 6.9E-55 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 HL41_06505 c6a4de85e3e727ae09234ddd3ed6811d 210 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 73 1.7E-10 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HL41_06505 c6a4de85e3e727ae09234ddd3ed6811d 210 Pfam PF01467 Cytidylyltransferase-like 11 182 2.4E-29 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HL41_06505 c6a4de85e3e727ae09234ddd3ed6811d 210 Gene3D G3DSA:3.40.50.620 6 210 1.4E-64 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_06505 c6a4de85e3e727ae09234ddd3ed6811d 210 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 7 210 30.809 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 HL41_06505 c6a4de85e3e727ae09234ddd3ed6811d 210 SUPERFAMILY SSF52374 7 210 1.16E-53 T 14-10-2018 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 SUPERFAMILY SSF54534 82 155 1.31E-22 T 14-10-2018 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 155 2.0E-28 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 SUPERFAMILY SSF46557 3 76 2.62E-27 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 PIRSF PIRSF006092 1 156 5.6E-54 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 6 155 2.1E-57 T 14-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 31.976 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 Gene3D G3DSA:3.10.50.30 78 156 2.2E-29 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 6.0E-31 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HL41_04950 e8163061af2215081e95960fc9e0d68b 156 Gene3D G3DSA:1.10.287.180 1 75 2.8E-31 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 HL41_05265 d42d73ed806e0e700e0bd191edaa534a 401 Pfam PF00872 Transposase, Mutator family 8 351 2.4E-63 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_07795 b47eed6768990a61d237347732ba08e7 117 Pfam PF01934 Protein of unknown function DUF86 15 110 3.5E-30 T 14-10-2018 IPR008201 Protein of unknown function DUF86 HL41_00370 d07d54024fbddfa6ab2faecd598da515 349 SUPERFAMILY SSF53335 145 262 9.09E-10 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_00370 d07d54024fbddfa6ab2faecd598da515 349 Pfam PF01861 Protein of unknown function DUF43 88 334 2.9E-82 T 14-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal HL41_00370 d07d54024fbddfa6ab2faecd598da515 349 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 3 336 41.677 T 14-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 HL41_00370 d07d54024fbddfa6ab2faecd598da515 349 Gene3D G3DSA:3.40.50.150 83 310 1.0E-74 T 14-10-2018 HL41_06260 72d68f68e0c04d0a890e27d8e2fdf9b6 321 SUPERFAMILY SSF53756 2 316 2.61E-79 T 14-10-2018 HL41_06260 72d68f68e0c04d0a890e27d8e2fdf9b6 321 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 5 316 7.8E-61 T 14-10-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 HL41_06260 72d68f68e0c04d0a890e27d8e2fdf9b6 321 Gene3D G3DSA:3.40.50.2000 143 318 5.7E-54 T 14-10-2018 HL41_06260 72d68f68e0c04d0a890e27d8e2fdf9b6 321 Gene3D G3DSA:3.40.50.2000 1 137 2.1E-24 T 14-10-2018 HL41_06260 72d68f68e0c04d0a890e27d8e2fdf9b6 321 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 69 298 1.7E-50 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 HL41_07910 0deec8e13ce3d0e2f32bc2f9c7c9b436 370 SUPERFAMILY SSF51569 1 356 5.59E-74 T 14-10-2018 HL41_07910 0deec8e13ce3d0e2f32bc2f9c7c9b436 370 Pfam PF00793 DAHP synthetase I family 100 356 2.6E-43 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 HL41_07910 0deec8e13ce3d0e2f32bc2f9c7c9b436 370 Gene3D G3DSA:3.20.20.70 85 356 8.5E-74 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_07910 0deec8e13ce3d0e2f32bc2f9c7c9b436 370 Gene3D G3DSA:3.30.70.1140 1 84 3.4E-8 T 14-10-2018 HL41_02615 f0b21283d63557c14a281ae3538127ba 258 Pfam PF01311 Bacterial export proteins, family 1 12 244 1.1E-48 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HL41_02615 f0b21283d63557c14a281ae3538127ba 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 20 41 1.6E-12 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HL41_02615 f0b21283d63557c14a281ae3538127ba 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 179 201 1.6E-12 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HL41_02615 f0b21283d63557c14a281ae3538127ba 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 201 220 1.6E-12 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HL41_04240 d9c0dd4474998b867371ef372fb13703 673 Gene3D G3DSA:3.30.450.90 252 387 2.8E-40 T 14-10-2018 HL41_04240 d9c0dd4474998b867371ef372fb13703 673 Gene3D G3DSA:3.40.50.300 389 673 1.3E-110 T 14-10-2018 HL41_04240 d9c0dd4474998b867371ef372fb13703 673 SUPERFAMILY SSF160246 119 246 5.75E-8 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily HL41_04240 d9c0dd4474998b867371ef372fb13703 673 SMART SM00382 414 549 2.8E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_04240 d9c0dd4474998b867371ef372fb13703 673 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 145 249 2.4E-6 T 14-10-2018 IPR007831 General secretory system II, protein E, N-terminal HL41_04240 d9c0dd4474998b867371ef372fb13703 673 Pfam PF00437 Type II/IV secretion system protein 285 553 2.8E-73 T 14-10-2018 IPR001482 Type II/IV secretion system protein HL41_04240 d9c0dd4474998b867371ef372fb13703 673 SUPERFAMILY SSF52540 276 670 3.16E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 Gene3D G3DSA:3.50.50.60 9 290 1.2E-72 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 SUPERFAMILY SSF51905 1 298 1.08E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 6.2E-30 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 6.2E-30 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 6.2E-30 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 6.2E-30 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 296 6.2E-30 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 6.2E-30 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 221 237 1.4E-20 T 14-10-2018 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.4E-20 T 14-10-2018 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 272 1.4E-20 T 14-10-2018 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.4E-20 T 14-10-2018 HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 Gene3D G3DSA:3.50.50.60 119 226 1.2E-72 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_00620 59f3d38c9af89ec3eae8985e3bc5026d 306 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 285 1.2E-32 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HL41_09055 30592343afa5352ff46fe035a1661186 121 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 116 1.4E-37 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HL41_09055 30592343afa5352ff46fe035a1661186 121 Pfam PF02261 Aspartate decarboxylase 1 112 3.2E-42 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HL41_09055 30592343afa5352ff46fe035a1661186 121 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 121 54.19 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HL41_09055 30592343afa5352ff46fe035a1661186 121 PIRSF PIRSF006246 1 120 8.9E-44 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HL41_09055 30592343afa5352ff46fe035a1661186 121 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 112 1.0E-25 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HL41_09055 30592343afa5352ff46fe035a1661186 121 Gene3D G3DSA:2.40.40.20 1 120 3.6E-42 T 14-10-2018 HL41_09055 30592343afa5352ff46fe035a1661186 121 SUPERFAMILY SSF50692 1 114 6.34E-39 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily HL41_05160 c7d7c031aee389ccda9789c8a3316534 290 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 3 280 2.5E-99 T 14-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related HL41_05160 c7d7c031aee389ccda9789c8a3316534 290 Gene3D G3DSA:1.10.357.140 10 161 8.2E-43 T 14-10-2018 HL41_05160 c7d7c031aee389ccda9789c8a3316534 290 Pfam PF01040 UbiA prenyltransferase family 20 264 6.6E-48 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 HL41_05160 c7d7c031aee389ccda9789c8a3316534 290 Gene3D G3DSA:1.20.120.1780 162 288 4.7E-36 T 14-10-2018 HL41_03415 2aa135e3498c9b138b818c1ee092758b 80 SMART SM00834 1 41 9.0E-18 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_03415 2aa135e3498c9b138b818c1ee092758b 80 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 51 7.1E-21 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_03415 2aa135e3498c9b138b818c1ee092758b 80 Pfam PF09723 Zinc ribbon domain 1 40 1.0E-17 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 Gene3D G3DSA:3.40.50.720 6 269 4.2E-115 T 14-10-2018 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 SUPERFAMILY SSF53223 5 122 2.11E-40 T 14-10-2018 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 Gene3D G3DSA:3.40.50.10860 8 286 4.2E-115 T 14-10-2018 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 266 284 2.5E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 209 238 2.5E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 2.5E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 2.5E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 2.5E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 249 265 2.5E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 2.5E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 270 278 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 293 40.38 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 1.3E-39 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 SUPERFAMILY SSF51735 123 291 2.63E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_07655 d9cfb2d6862e1c86bca7ae107e90f1be 301 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 291 1.2E-71 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 SMART SM00448 369 476 7.4E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 SUPERFAMILY SSF52172 367 479 4.84E-24 T 14-10-2018 IPR011006 CheY-like superfamily HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 Gene3D G3DSA:3.30.565.10 200 351 2.4E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 126 8.0E-7 T 14-10-2018 IPR000014 PAS domain HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 351 2.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 313 2.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 332 2.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 299 2.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 Gene3D G3DSA:3.40.50.2300 360 481 3.6E-22 T 14-10-2018 HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 Gene3D G3DSA:3.30.450.20 21 137 4.3E-8 T 14-10-2018 HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 SUPERFAMILY SSF55874 199 353 9.3E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 SUPERFAMILY SSF55785 30 114 7.68E-6 T 14-10-2018 IPR035965 PAS domain superfamily HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 SMART SM00387 245 354 2.7E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 Pfam PF00072 Response regulator receiver domain 371 476 4.5E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 246 352 1.2E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_00340 87e637ae852e859cd37a2ae5a348c238 481 Gene3D G3DSA:1.10.287.130 140 199 2.4E-38 T 14-10-2018 HL41_02935 b39ad4ef08ae197a054f9cd0eb268a4d 531 SUPERFAMILY SSF56317 232 491 8.24E-39 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily HL41_02935 b39ad4ef08ae197a054f9cd0eb268a4d 531 Gene3D G3DSA:3.60.110.10 228 494 9.8E-18 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily HL41_02935 b39ad4ef08ae197a054f9cd0eb268a4d 531 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 59 474 1.5E-91 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 HL41_02935 b39ad4ef08ae197a054f9cd0eb268a4d 531 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 5 516 20.908 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 HL41_02935 b39ad4ef08ae197a054f9cd0eb268a4d 531 Pfam PF00795 Carbon-nitrogen hydrolase 236 491 8.0E-23 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 HL41_05420 8c6a64c5cb0687c12574a9ec3dee28e2 118 SUPERFAMILY SSF54843 2 112 7.59E-47 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05420 8c6a64c5cb0687c12574a9ec3dee28e2 118 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 2.8E-46 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05420 8c6a64c5cb0687c12574a9ec3dee28e2 118 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 4.7E-40 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HL41_05420 8c6a64c5cb0687c12574a9ec3dee28e2 118 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.498 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05420 8c6a64c5cb0687c12574a9ec3dee28e2 118 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05420 8c6a64c5cb0687c12574a9ec3dee28e2 118 Gene3D G3DSA:3.90.470.10 1 117 1.8E-50 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05580 7cd7f35bbbe064c2b13a13249dcecdab 98 Pfam PF00226 DnaJ domain 16 61 2.1E-11 T 14-10-2018 IPR001623 DnaJ domain HL41_05580 7cd7f35bbbe064c2b13a13249dcecdab 98 Gene3D G3DSA:1.10.287.110 4 63 6.0E-19 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_05580 7cd7f35bbbe064c2b13a13249dcecdab 98 SMART SM00271 11 65 3.0E-10 T 14-10-2018 IPR001623 DnaJ domain HL41_05580 7cd7f35bbbe064c2b13a13249dcecdab 98 SUPERFAMILY SSF46565 13 91 1.57E-17 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_01505 3b6f89238e7f8d8799e5f0b5076c0d6f 72 Pfam PF06005 Cell division protein ZapB 1 71 1.1E-8 T 14-10-2018 IPR009252 Cell division protein ZapB GO:0005737|GO:0043093|GO:0090529 HL41_00690 932e882c1eb4860363c52e2867ec1166 868 SUPERFAMILY SSF159501 620 817 7.59E-14 T 14-10-2018 HL41_00690 932e882c1eb4860363c52e2867ec1166 868 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 630 816 2.7E-15 T 14-10-2018 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN HL41_05440 afb504ecc896ec1ea91902b974d364c0 210 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 19 206 1.6E-74 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05440 afb504ecc896ec1ea91902b974d364c0 210 SUPERFAMILY SSF52166 5 208 1.83E-76 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05440 afb504ecc896ec1ea91902b974d364c0 210 Pfam PF00573 Ribosomal protein L4/L1 family 20 207 3.0E-65 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 HL41_05440 afb504ecc896ec1ea91902b974d364c0 210 Gene3D G3DSA:3.40.1370.10 1 210 1.1E-77 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05440 afb504ecc896ec1ea91902b974d364c0 210 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 11 209 34.528 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04345 1fac9492281e9677228c833b6129f4f5 190 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 179 1.1E-37 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HL41_04345 1fac9492281e9677228c833b6129f4f5 190 SUPERFAMILY SSF53323 4 186 9.68E-41 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HL41_04345 1fac9492281e9677228c833b6129f4f5 190 Gene3D G3DSA:3.40.920.10 1 190 1.5E-54 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HL41_00895 8472edd18f0687e84ec645c40ea338d2 213 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 12 208 1.3E-44 T 14-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 HL41_00895 8472edd18f0687e84ec645c40ea338d2 213 Pfam PF02666 Phosphatidylserine decarboxylase 42 205 2.1E-27 T 14-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 HL41_03265 b70c77876e27e6051cee0786cc40d63f 259 Gene3D G3DSA:3.20.20.150 5 255 2.1E-47 T 14-10-2018 HL41_03265 b70c77876e27e6051cee0786cc40d63f 259 SUPERFAMILY SSF51658 31 253 1.52E-34 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily HL41_03265 b70c77876e27e6051cee0786cc40d63f 259 Pfam PF01261 Xylose isomerase-like TIM barrel 39 214 1.4E-17 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HL41_02405 2b1168151b4f61e3ba33ca634a8a5fca 144 SUPERFAMILY SSF46785 4 135 6.26E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily HL41_02405 2b1168151b4f61e3ba33ca634a8a5fca 144 Gene3D G3DSA:1.10.10.10 1 142 4.0E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_02405 2b1168151b4f61e3ba33ca634a8a5fca 144 Pfam PF02082 Transcriptional regulator 3 85 6.6E-19 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type HL41_02405 2b1168151b4f61e3ba33ca634a8a5fca 144 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 134 3.0E-29 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type HL41_03395 f0211c2159a1c7a11a1ef8d870114547 360 SUPERFAMILY SSF100950 2 351 1.95E-105 T 14-10-2018 IPR037171 NagB/RpiA transferase-like HL41_03395 f0211c2159a1c7a11a1ef8d870114547 360 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 1 355 38.574 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HL41_03395 f0211c2159a1c7a11a1ef8d870114547 360 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 28 345 1.8E-102 T 14-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HL41_03395 f0211c2159a1c7a11a1ef8d870114547 360 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 3 344 1.8E-122 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HL41_03395 f0211c2159a1c7a11a1ef8d870114547 360 Gene3D G3DSA:1.20.120.420 1 158 2.9E-36 T 14-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 HL41_03395 f0211c2159a1c7a11a1ef8d870114547 360 Gene3D G3DSA:3.40.50.10470 162 359 1.0E-64 T 14-10-2018 HL41_03395 f0211c2159a1c7a11a1ef8d870114547 360 Pfam PF01008 Initiation factor 2 subunit family 43 345 5.0E-73 T 14-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 HL41_04965 3846f2a99136f070212703cfdb6e742b 318 SUPERFAMILY SSF55347 154 279 2.94E-10 T 14-10-2018 HL41_04965 3846f2a99136f070212703cfdb6e742b 318 SUPERFAMILY SSF51735 3 157 1.13E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_04965 3846f2a99136f070212703cfdb6e742b 318 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 125 2.3E-25 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 HL41_04965 3846f2a99136f070212703cfdb6e742b 318 Gene3D G3DSA:3.30.360.10 128 310 4.7E-24 T 14-10-2018 HL41_04965 3846f2a99136f070212703cfdb6e742b 318 Gene3D G3DSA:3.40.50.720 1 127 1.3E-32 T 14-10-2018 HL41_01305 078c5bfe415bbcd450c771f15b76c501 117 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_01305 078c5bfe415bbcd450c771f15b76c501 117 Gene3D G3DSA:3.30.700.10 7 116 8.5E-25 T 14-10-2018 HL41_01305 078c5bfe415bbcd450c771f15b76c501 117 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 2.4E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_01305 078c5bfe415bbcd450c771f15b76c501 117 SUPERFAMILY SSF54523 7 101 1.1E-18 T 14-10-2018 HL41_01305 078c5bfe415bbcd450c771f15b76c501 117 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 5.9E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_01920 6127fba1b2e5d538737e0c2dcccd5897 66 Pfam PF02635 DsrE/DsrF-like family 1 46 2.9E-5 T 14-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein HL41_01920 6127fba1b2e5d538737e0c2dcccd5897 66 SUPERFAMILY SSF75169 1 44 2.19E-8 T 14-10-2018 IPR027396 DsrEFH-like HL41_01920 6127fba1b2e5d538737e0c2dcccd5897 66 Gene3D G3DSA:3.40.1260.10 1 61 5.7E-7 T 14-10-2018 IPR027396 DsrEFH-like HL41_00590 21d29171fb5a7afbe8b601c6ab4bee44 229 Pfam PF06508 Queuosine biosynthesis protein QueC 14 220 1.7E-73 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HL41_00590 21d29171fb5a7afbe8b601c6ab4bee44 229 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 14 213 3.5E-61 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HL41_00590 21d29171fb5a7afbe8b601c6ab4bee44 229 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 12 226 51.117 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HL41_00590 21d29171fb5a7afbe8b601c6ab4bee44 229 Gene3D G3DSA:3.40.50.620 12 227 2.1E-73 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_00590 21d29171fb5a7afbe8b601c6ab4bee44 229 PIRSF PIRSF006293 10 229 5.4E-76 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HL41_00590 21d29171fb5a7afbe8b601c6ab4bee44 229 SUPERFAMILY SSF52402 14 228 2.37E-52 T 14-10-2018 HL41_08120 93b6b147a184c2ea68ec47ce585b7044 433 SUPERFAMILY SSF52980 11 398 3.81E-29 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HL41_00670 41dd49a905e3640469e45e3eddc620ee 279 SUPERFAMILY SSF102705 4 259 3.53E-66 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily HL41_00670 41dd49a905e3640469e45e3eddc620ee 279 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 255 7.0E-51 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HL41_00670 41dd49a905e3640469e45e3eddc620ee 279 Gene3D G3DSA:3.40.1390.30 102 225 2.0E-57 T 14-10-2018 HL41_00670 41dd49a905e3640469e45e3eddc620ee 279 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 243 1.1E-62 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HL41_00670 41dd49a905e3640469e45e3eddc620ee 279 Gene3D G3DSA:3.40.1390.30 10 235 2.0E-57 T 14-10-2018 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 207 228 1.6E-31 T 14-10-2018 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 229 255 1.6E-31 T 14-10-2018 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 177 1.6E-31 T 14-10-2018 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 1.6E-31 T 14-10-2018 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 80 105 1.6E-31 T 14-10-2018 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 298 310 1.6E-31 T 14-10-2018 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 343 365 4.9E-5 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 32 51 4.9E-5 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 479 500 4.9E-5 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 Pfam PF00361 Proton-conducting membrane transporter 132 409 2.4E-57 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_07360 eaf5e6db574096371b75f7ed4958880c 587 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 63 119 7.0E-9 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_01165 bc45df09c72a1f948d42efc1c94bfab4 315 Gene3D G3DSA:3.40.718.10 2 315 3.3E-115 T 14-10-2018 HL41_01165 bc45df09c72a1f948d42efc1c94bfab4 315 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 39 309 8.0E-96 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 HL41_01165 bc45df09c72a1f948d42efc1c94bfab4 315 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 5 312 7.5E-102 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 HL41_01165 bc45df09c72a1f948d42efc1c94bfab4 315 SUPERFAMILY SSF53659 5 313 6.04E-98 T 14-10-2018 HL41_00460 939d0781b253d4d3daee7956f2280919 176 Pfam PF05951 Bacterial protein of unknown function (DUF882) 30 174 2.3E-48 T 14-10-2018 IPR010275 Protein of unknown function DUF882 HL41_00460 939d0781b253d4d3daee7956f2280919 176 Gene3D G3DSA:3.30.1380.10 92 176 2.0E-7 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HL41_00460 939d0781b253d4d3daee7956f2280919 176 SUPERFAMILY SSF55166 62 175 8.11E-27 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 PIRSF PIRSF039144 1 112 1.8E-49 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 Gene3D G3DSA:3.30.70.120 1 112 7.6E-46 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 PRINTS PR00340 P-II protein signature 52 75 3.0E-40 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 PRINTS PR00340 P-II protein signature 83 103 3.0E-40 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 PRINTS PR00340 P-II protein signature 23 41 3.0E-40 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 PRINTS PR00340 P-II protein signature 2 17 3.0E-40 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.4E-39 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 SMART SM00938 4 105 9.0E-56 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 HL41_02145 cf023e11bc5c0ed9aaa1660fbc2b163a 112 SUPERFAMILY SSF54913 1 112 3.02E-42 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta HL41_00040 d2eee6000a5a6a3cab0a3bce66cb4a3d 313 Pfam PF01384 Phosphate transporter family 16 301 8.0E-58 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 HL41_07920 2835c191774bf4f6132b7a1851325825 264 SUPERFAMILY SSF56059 73 247 1.61E-18 T 14-10-2018 HL41_07920 2835c191774bf4f6132b7a1851325825 264 Gene3D G3DSA:3.30.470.20 158 262 9.8E-9 T 14-10-2018 HL41_07920 2835c191774bf4f6132b7a1851325825 264 Pfam PF08443 RimK-like ATP-grasp domain 104 240 1.7E-7 T 14-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 HL41_06145 c2f568cda2c5c1cc0d4b8c2635db9e0f 142 Gene3D G3DSA:3.30.70.20 24 141 1.6E-31 T 14-10-2018 HL41_06145 c2f568cda2c5c1cc0d4b8c2635db9e0f 142 Pfam PF12800 4Fe-4S binding domain 9 22 0.024 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_06145 c2f568cda2c5c1cc0d4b8c2635db9e0f 142 SUPERFAMILY SSF54862 2 130 1.26E-41 T 14-10-2018 HL41_06145 c2f568cda2c5c1cc0d4b8c2635db9e0f 142 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_06145 c2f568cda2c5c1cc0d4b8c2635db9e0f 142 Pfam PF13247 4Fe-4S dicluster domain 44 131 5.2E-20 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_02700 452cd55eecb8eedcd2efb38279ad55c1 386 Pfam PF03749 Sugar fermentation stimulation protein 15 223 5.2E-45 T 14-10-2018 IPR005224 Sugar fermentation stimulation protein HL41_02700 452cd55eecb8eedcd2efb38279ad55c1 386 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 8 223 2.7E-47 T 14-10-2018 IPR005224 Sugar fermentation stimulation protein HL41_02700 452cd55eecb8eedcd2efb38279ad55c1 386 Pfam PF01986 Domain of unknown function DUF123 272 358 4.8E-24 T 14-10-2018 IPR002837 Protein of unknown function DUF123 HL41_02700 452cd55eecb8eedcd2efb38279ad55c1 386 Gene3D G3DSA:2.40.50.580 1 84 1.2E-14 T 14-10-2018 HL41_02700 452cd55eecb8eedcd2efb38279ad55c1 386 Gene3D G3DSA:3.40.1350.60 85 234 2.5E-35 T 14-10-2018 HL41_02915 f7e8ebedd9414549a76cf70d9ca911a1 292 SUPERFAMILY SSF52540 34 285 1.57E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02915 f7e8ebedd9414549a76cf70d9ca911a1 292 Gene3D G3DSA:3.40.50.300 26 288 5.1E-37 T 14-10-2018 HL41_02915 f7e8ebedd9414549a76cf70d9ca911a1 292 TIGRFAM TIGR03878 thermo_KaiC_2: KaiC domain protein, AF_0795 family 32 290 2.1E-141 T 14-10-2018 IPR022373 KaiC domain-containing protein HL41_02915 f7e8ebedd9414549a76cf70d9ca911a1 292 Pfam PF06745 KaiC 35 287 1.7E-64 T 14-10-2018 IPR014774 KaiC-like domain HL41_02850 c5dfba3518e3e6c6c63830358f14c7b1 277 Pfam PF01297 Zinc-uptake complex component A periplasmic 26 270 1.0E-29 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 HL41_02850 c5dfba3518e3e6c6c63830358f14c7b1 277 Gene3D G3DSA:3.40.50.1980 23 163 7.2E-24 T 14-10-2018 HL41_02850 c5dfba3518e3e6c6c63830358f14c7b1 277 Gene3D G3DSA:3.40.50.1980 168 274 9.2E-8 T 14-10-2018 HL41_02850 c5dfba3518e3e6c6c63830358f14c7b1 277 SUPERFAMILY SSF53807 24 274 1.08E-39 T 14-10-2018 HL41_03700 d6cca1f9d46520530da741fc1862e885 122 PRINTS PR00609 Class III cytochrome C signature 112 119 6.2E-8 T 14-10-2018 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HL41_03700 d6cca1f9d46520530da741fc1862e885 122 PRINTS PR00609 Class III cytochrome C signature 53 60 6.2E-8 T 14-10-2018 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HL41_03700 d6cca1f9d46520530da741fc1862e885 122 PRINTS PR00609 Class III cytochrome C signature 94 105 6.2E-8 T 14-10-2018 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HL41_03700 d6cca1f9d46520530da741fc1862e885 122 PRINTS PR00609 Class III cytochrome C signature 39 48 6.2E-8 T 14-10-2018 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HL41_03700 d6cca1f9d46520530da741fc1862e885 122 SUPERFAMILY SSF48695 16 120 5.82E-15 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_03700 d6cca1f9d46520530da741fc1862e885 122 Gene3D G3DSA:3.90.10.10 18 122 5.3E-22 T 14-10-2018 HL41_03700 d6cca1f9d46520530da741fc1862e885 122 Pfam PF02085 Class III cytochrome C family 35 119 3.2E-18 T 14-10-2018 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HL41_00075 f9b30b5034dadcfaa981d02d41b2f6c6 124 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 52 109 2.5E-18 T 14-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HL41_00075 f9b30b5034dadcfaa981d02d41b2f6c6 124 Gene3D G3DSA:1.20.20.10 36 113 1.4E-27 T 14-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00075 f9b30b5034dadcfaa981d02d41b2f6c6 124 SUPERFAMILY SSF81333 38 111 6.02E-20 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily HL41_00075 f9b30b5034dadcfaa981d02d41b2f6c6 124 Hamap MF_01396 ATP synthase subunit c [atpH]. 42 107 15.658 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00075 f9b30b5034dadcfaa981d02d41b2f6c6 124 Pfam PF00137 ATP synthase subunit C 43 106 4.8E-16 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HL41_00075 f9b30b5034dadcfaa981d02d41b2f6c6 124 ProSitePatterns PS00605 ATP synthase c subunit signature. 72 93 - T 14-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00075 f9b30b5034dadcfaa981d02d41b2f6c6 124 PRINTS PR00124 ATP synthase C subunit signature 82 107 1.8E-19 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00075 f9b30b5034dadcfaa981d02d41b2f6c6 124 PRINTS PR00124 ATP synthase C subunit signature 65 80 1.8E-19 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_00075 f9b30b5034dadcfaa981d02d41b2f6c6 124 PRINTS PR00124 ATP synthase C subunit signature 44 63 1.8E-19 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 SUPERFAMILY SSF58104 216 523 3.01E-68 T 14-10-2018 HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 Pfam PF13682 Chemoreceptor zinc-binding domain 541 607 3.3E-9 T 14-10-2018 IPR025991 Chemoreceptor zinc-binding domain HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 Gene3D G3DSA:1.10.287.950 197 513 2.8E-70 T 14-10-2018 HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 420 1.8E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 15 40 1.8E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 285 314 1.8E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 362 389 1.8E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 439 468 1.8E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 SMART SM00283 264 525 6.7E-67 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02365 7de6bc92692bb33c37b49bbff554d727 650 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 330 492 1.1E-45 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 Gene3D G3DSA:1.10.8.540 497 585 3.2E-27 T 14-10-2018 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 69 88 1.1E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 236 250 1.1E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 155 173 1.1E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 32 45 1.1E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 136 152 1.1E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 185 202 1.1E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 Pfam PF00771 FHIPEP family 27 675 1.6E-256 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 Gene3D G3DSA:3.40.30.60 352 496 3.6E-51 T 14-10-2018 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 16 684 2.1E-253 T 14-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 Gene3D G3DSA:1.10.490.80 586 684 5.6E-23 T 14-10-2018 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 PIRSF PIRSF005419 1 689 2.1E-251 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HL41_02605 3c4f5b715d24427984b25aa94721894b 689 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 141 164 - T 14-10-2018 IPR025505 FHIPEP conserved site HL41_08485 f017c1e7e68a63b9ee5977e6b054b3ac 514 Pfam PF00474 Sodium:solute symporter family 42 441 1.5E-112 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HL41_08485 f017c1e7e68a63b9ee5977e6b054b3ac 514 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site HL41_08485 f017c1e7e68a63b9ee5977e6b054b3ac 514 Gene3D G3DSA:1.20.1730.10 30 511 6.8E-67 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily HL41_08485 f017c1e7e68a63b9ee5977e6b054b3ac 514 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 42 441 4.8E-67 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 HL41_06925 c189033f317cfb5c4f4aaf8ee9c194fb 224 Pfam PF13643 Domain of unknown function (DUF4145) 131 204 8.2E-14 T 14-10-2018 IPR025285 Domain of unknown function DUF4145 HL41_06490 aa91aadaf7629cf3c12cf66a8b5b77e5 383 PIRSF PIRSF016719 2 383 2.7E-103 T 14-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 HL41_06490 aa91aadaf7629cf3c12cf66a8b5b77e5 383 Pfam PF07075 Protein of unknown function (DUF1343) 16 382 3.2E-106 T 14-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 HL41_06490 aa91aadaf7629cf3c12cf66a8b5b77e5 383 Gene3D G3DSA:3.90.1150.140 216 363 1.5E-32 T 14-10-2018 HL41_06490 aa91aadaf7629cf3c12cf66a8b5b77e5 383 Gene3D G3DSA:3.40.50.12170 2 215 6.8E-70 T 14-10-2018 HL41_08675 491067386ba7e1c1810b750150a2ef4c 127 Gene3D G3DSA:1.20.58.1610 4 123 4.1E-36 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08675 491067386ba7e1c1810b750150a2ef4c 127 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 7 124 17.846 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 HL41_08675 491067386ba7e1c1810b750150a2ef4c 127 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 26 123 1.5E-30 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06465 20cb30ae1bad30945a6b9cd185aeda3b 325 Gene3D G3DSA:3.40.50.720 6 253 4.7E-123 T 14-10-2018 HL41_06465 20cb30ae1bad30945a6b9cd185aeda3b 325 SUPERFAMILY SSF51735 1 323 7.48E-92 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_06465 20cb30ae1bad30945a6b9cd185aeda3b 325 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 5 324 8.0E-138 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 HL41_06465 20cb30ae1bad30945a6b9cd185aeda3b 325 Gene3D G3DSA:3.90.25.10 174 307 4.7E-123 T 14-10-2018 HL41_06465 20cb30ae1bad30945a6b9cd185aeda3b 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 253 6.2E-56 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HL41_04870 70335bc3d321fe4a6e3dd46d0c124fcf 119 SUPERFAMILY SSF53146 1 119 4.58E-36 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily HL41_04870 70335bc3d321fe4a6e3dd46d0c124fcf 119 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 99 5.5E-23 T 14-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HL41_04870 70335bc3d321fe4a6e3dd46d0c124fcf 119 Gene3D G3DSA:3.30.420.130 1 101 4.9E-34 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily HL41_03790 e7536b4d099f0674ec66eaf54212629f 385 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 2 381 5.5E-149 T 14-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 HL41_03305 b2dd817eafc2e4b588d4e24e150bee14 216 Gene3D G3DSA:3.20.20.70 6 216 1.8E-40 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_03305 b2dd817eafc2e4b588d4e24e150bee14 216 SUPERFAMILY SSF102114 30 114 5.49E-18 T 14-10-2018 HL41_03305 b2dd817eafc2e4b588d4e24e150bee14 216 Pfam PF04055 Radical SAM superfamily 31 111 1.0E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_03305 b2dd817eafc2e4b588d4e24e150bee14 216 Pfam PF13394 4Fe-4S single cluster domain 29 115 1.4E-14 T 14-10-2018 HL41_03305 b2dd817eafc2e4b588d4e24e150bee14 216 PIRSF PIRSF000370 5 216 1.0E-62 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 HL41_03305 b2dd817eafc2e4b588d4e24e150bee14 216 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 7 216 36.441 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 HL41_05745 f839c476488c5fa921273d2be6d10311 413 Pfam PF06245 Protein of unknown function (DUF1015) 5 402 1.0E-95 T 14-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 HL41_05745 f839c476488c5fa921273d2be6d10311 413 PIRSF PIRSF033563 1 405 6.5E-80 T 14-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 HL41_06935 d206f7f28417c7f0ba7b6320c7a35698 647 Gene3D G3DSA:3.30.420.10 240 470 4.6E-21 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 HL41_06935 d206f7f28417c7f0ba7b6320c7a35698 647 SUPERFAMILY SSF53098 251 464 1.44E-9 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily HL41_06935 d206f7f28417c7f0ba7b6320c7a35698 647 Pfam PF12728 Helix-turn-helix domain 7 53 8.4E-7 T 14-10-2018 HL41_06935 d206f7f28417c7f0ba7b6320c7a35698 647 Pfam PF13384 Homeodomain-like domain 111 148 1.2E-6 T 14-10-2018 HL41_06515 ae0945f7d4a5faea68246781b9582caf 525 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 346 477 2.5E-14 T 14-10-2018 IPR000160 GGDEF domain HL41_06515 ae0945f7d4a5faea68246781b9582caf 525 SMART SM00267 339 516 9.4E-8 T 14-10-2018 IPR000160 GGDEF domain HL41_06515 ae0945f7d4a5faea68246781b9582caf 525 SUPERFAMILY SSF109604 36 274 1.35E-23 T 14-10-2018 HL41_06515 ae0945f7d4a5faea68246781b9582caf 525 Pfam PF00990 Diguanylate cyclase, GGDEF domain 351 510 3.2E-13 T 14-10-2018 IPR000160 GGDEF domain HL41_06515 ae0945f7d4a5faea68246781b9582caf 525 Pfam PF08668 HDOD domain 45 205 4.1E-20 T 14-10-2018 IPR013976 Metal-dependent hydrolase HDOD HL41_06515 ae0945f7d4a5faea68246781b9582caf 525 SUPERFAMILY SSF55073 355 462 4.47E-13 T 14-10-2018 IPR029787 Nucleotide cyclase HL41_06515 ae0945f7d4a5faea68246781b9582caf 525 Gene3D G3DSA:1.10.3210.10 12 274 2.4E-26 T 14-10-2018 HL41_06515 ae0945f7d4a5faea68246781b9582caf 525 Gene3D G3DSA:3.30.70.270 336 514 4.6E-20 T 14-10-2018 HL41_08410 6e26c20ac61e3c9a31d50b6eaac8c4ba 108 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 84 3.9E-21 T 14-10-2018 HL41_08410 6e26c20ac61e3c9a31d50b6eaac8c4ba 108 Gene3D G3DSA:3.10.20.740 3 104 3.7E-31 T 14-10-2018 HL41_08410 6e26c20ac61e3c9a31d50b6eaac8c4ba 108 SUPERFAMILY SSF54292 4 93 4.59E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 HL41_01875 bcd08db464ae8169b8549deb96e8b170 500 Pfam PF13361 UvrD-like helicase C-terminal domain 395 459 2.6E-17 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HL41_01875 bcd08db464ae8169b8549deb96e8b170 500 Pfam PF13245 AAA domain 18 199 5.5E-26 T 14-10-2018 HL41_01875 bcd08db464ae8169b8549deb96e8b170 500 SUPERFAMILY SSF52540 3 481 6.44E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08615 b326af1ced53ca4c570ed7e648ce163e 400 SUPERFAMILY SSF82171 51 361 2.51E-10 T 14-10-2018 HL41_08615 b326af1ced53ca4c570ed7e648ce163e 400 Gene3D G3DSA:2.120.10.30 255 367 3.7E-6 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like HL41_08615 b326af1ced53ca4c570ed7e648ce163e 400 SUPERFAMILY SSF82171 15 157 3.92E-5 T 14-10-2018 HL41_08125 a6523df1566a8f8f88f4bac19039afb6 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 30.595 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HL41_08125 a6523df1566a8f8f88f4bac19039afb6 158 Gene3D G3DSA:3.30.1330.50 1 158 4.6E-59 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HL41_08125 a6523df1566a8f8f88f4bac19039afb6 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 154 1.6E-52 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HL41_08125 a6523df1566a8f8f88f4bac19039afb6 158 SUPERFAMILY SSF69765 2 155 2.75E-52 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HL41_08125 a6523df1566a8f8f88f4bac19039afb6 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 14-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HL41_08125 a6523df1566a8f8f88f4bac19039afb6 158 Pfam PF02542 YgbB family 2 154 1.6E-54 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HL41_00325 c42b1fe84871068fc7c870707e0bf0db 76 Pfam PF16256 Domain of unknown function (DUF4911) 8 63 3.9E-15 T 14-10-2018 IPR032587 Protein of unknown function DUF4911 HL41_01005 e07b651ce35978bd7ca2599614482533 416 SUPERFAMILY SSF69304 146 413 1.57E-33 T 14-10-2018 HL41_01005 e07b651ce35978bd7ca2599614482533 416 Pfam PF07676 WD40-like Beta Propeller Repeat 313 342 0.0086 T 14-10-2018 IPR011659 WD40-like Beta Propeller HL41_01005 e07b651ce35978bd7ca2599614482533 416 Gene3D G3DSA:2.120.10.30 157 415 5.0E-35 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like HL41_04620 795132ea6289174d05c0dbb9e5f41247 67 ProSitePatterns PS00202 Rubredoxin signature. 41 51 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 HL41_04620 795132ea6289174d05c0dbb9e5f41247 67 Gene3D G3DSA:2.20.28.10 5 62 1.2E-22 T 14-10-2018 HL41_04620 795132ea6289174d05c0dbb9e5f41247 67 SUPERFAMILY SSF57802 8 61 9.09E-19 T 14-10-2018 HL41_04620 795132ea6289174d05c0dbb9e5f41247 67 PRINTS PR00163 Rubredoxin signature 41 57 8.4E-6 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 HL41_04620 795132ea6289174d05c0dbb9e5f41247 67 PRINTS PR00163 Rubredoxin signature 11 27 8.4E-6 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 HL41_04620 795132ea6289174d05c0dbb9e5f41247 67 Pfam PF00301 Rubredoxin 10 57 4.8E-20 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 HL41_08580 ca6552c2794891ef2ed81dfafd45c53a 242 SUPERFAMILY SSF54862 1 173 2.51E-57 T 14-10-2018 HL41_08580 ca6552c2794891ef2ed81dfafd45c53a 242 PIRSF PIRSF036298 2 238 1.1E-65 T 14-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 HL41_08580 ca6552c2794891ef2ed81dfafd45c53a 242 Pfam PF13247 4Fe-4S dicluster domain 66 163 4.0E-30 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_08580 ca6552c2794891ef2ed81dfafd45c53a 242 Gene3D G3DSA:3.30.70.20 77 135 6.2E-63 T 14-10-2018 HL41_08580 ca6552c2794891ef2ed81dfafd45c53a 242 Pfam PF12800 4Fe-4S binding domain 10 25 0.15 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_08580 ca6552c2794891ef2ed81dfafd45c53a 242 Gene3D G3DSA:3.30.70.20 6 172 6.2E-63 T 14-10-2018 HL41_08580 ca6552c2794891ef2ed81dfafd45c53a 242 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 108 119 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 Gene3D G3DSA:1.10.287.130 213 268 2.1E-11 T 14-10-2018 HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 266 2.8E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 SMART SM00388 209 274 4.2E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 Gene3D G3DSA:3.30.565.10 269 420 5.1E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 419 2.0E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 SUPERFAMILY SSF55874 261 420 3.01E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 2.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 2.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 2.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 2.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 SMART SM00387 314 420 1.3E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase HL41_07255 6ba9e2526438f3638fd4ff994347c2d0 420 SUPERFAMILY SSF47384 204 272 1.63E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 HL41_00540 d56c5356aa3f3ec2c177aff98bdc482e 97 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 19 97 3.3E-21 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HL41_00540 d56c5356aa3f3ec2c177aff98bdc482e 97 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 6 97 15.693 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HL41_00540 d56c5356aa3f3ec2c177aff98bdc482e 97 Pfam PF02049 Flagellar hook-basal body complex protein FliE 20 97 1.5E-24 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HL41_00540 d56c5356aa3f3ec2c177aff98bdc482e 97 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 27 43 2.1E-11 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HL41_00540 d56c5356aa3f3ec2c177aff98bdc482e 97 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 82 95 2.1E-11 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HL41_00540 d56c5356aa3f3ec2c177aff98bdc482e 97 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 61 77 2.1E-11 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HL41_01965 e993dc060aa3211d5fb88dca5ebf5bfa 215 SMART SM00849 14 191 1.3E-36 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_01965 e993dc060aa3211d5fb88dca5ebf5bfa 215 Gene3D G3DSA:3.60.15.10 1 214 1.0E-70 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_01965 e993dc060aa3211d5fb88dca5ebf5bfa 215 Pfam PF00753 Metallo-beta-lactamase superfamily 15 191 6.4E-28 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_01965 e993dc060aa3211d5fb88dca5ebf5bfa 215 SUPERFAMILY SSF56281 1 212 5.24E-56 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_04300 5515f52ebb083ebba2974eab0a474c7c 132 Gene3D G3DSA:3.30.420.270 57 126 3.7E-11 T 14-10-2018 HL41_04300 5515f52ebb083ebba2974eab0a474c7c 132 Pfam PF02472 Biopolymer transport protein ExbD/TolR 5 130 3.1E-27 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 HL41_08240 9219bde9f87886b04d21a8a1ebfab8f5 139 SMART SM00448 3 115 6.1E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_08240 9219bde9f87886b04d21a8a1ebfab8f5 139 SUPERFAMILY SSF52172 4 136 4.13E-42 T 14-10-2018 IPR011006 CheY-like superfamily HL41_08240 9219bde9f87886b04d21a8a1ebfab8f5 139 Gene3D G3DSA:3.40.50.2300 2 138 3.2E-42 T 14-10-2018 HL41_08240 9219bde9f87886b04d21a8a1ebfab8f5 139 Pfam PF00072 Response regulator receiver domain 5 113 1.2E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_00570 e94cf0b00d0999669a23afa6ae176e70 195 SUPERFAMILY SSF158791 117 189 1.7E-10 T 14-10-2018 HL41_00570 e94cf0b00d0999669a23afa6ae176e70 195 Pfam PF03448 MgtE intracellular N domain 134 189 3.6E-9 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain HL41_00570 e94cf0b00d0999669a23afa6ae176e70 195 Gene3D G3DSA:1.25.60.10 74 189 2.4E-8 T 14-10-2018 IPR038076 MgtE, N-terminal domain superfamily HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 Pfam PF00579 tRNA synthetases class I (W and Y) 2 284 6.2E-68 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 Gene3D G3DSA:1.10.240.10 191 296 2.2E-114 T 14-10-2018 HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 SUPERFAMILY SSF52374 4 327 5.63E-88 T 14-10-2018 HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 327 2.0E-92 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 145 166 1.8E-23 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 196 206 1.8E-23 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 1.8E-23 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 1.8E-23 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HL41_03690 fd66fa014d02fb3a6daa8eaf39532ed6 331 Gene3D G3DSA:3.40.50.620 6 323 2.2E-114 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_04865 36dd83ab2ba54ba5659c2dc97a1e672e 106 Pfam PF17253 Family of unknown function (DUF5320) 1 101 7.2E-30 T 14-10-2018 IPR035205 Protein of unknown function DUF5320 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 293 6.4E-52 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 SUPERFAMILY SSF51905 4 308 1.0E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 Gene3D G3DSA:3.50.50.60 124 246 4.1E-115 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 5.6E-66 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 5.6E-66 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 5.6E-66 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 5.6E-66 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 5.6E-66 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 5.6E-66 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 5.6E-66 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 5.6E-66 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 5.6E-66 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 Gene3D G3DSA:3.50.50.60 10 305 4.1E-115 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 3.6E-32 T 14-10-2018 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.6E-32 T 14-10-2018 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 3.6E-32 T 14-10-2018 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.6E-32 T 14-10-2018 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 3.6E-32 T 14-10-2018 HL41_08750 b3aba75a54869e594887c1ab7c1dd413 312 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 306 1.7E-116 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 HL41_06010 949ac47d1b35822afe287eab2567d47c 267 SUPERFAMILY SSF56219 1 265 9.95E-71 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily HL41_06010 949ac47d1b35822afe287eab2567d47c 267 Gene3D G3DSA:3.60.10.10 1 266 7.4E-69 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily HL41_06010 949ac47d1b35822afe287eab2567d47c 267 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 14-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 HL41_06010 949ac47d1b35822afe287eab2567d47c 267 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 265 7.0E-78 T 14-10-2018 HL41_06010 949ac47d1b35822afe287eab2567d47c 267 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 265 1.1E-71 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 HL41_06010 949ac47d1b35822afe287eab2567d47c 267 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 258 6.5E-23 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase HL41_07720 401ef74a26f8b196d00498163ec72690 252 Gene3D G3DSA:1.10.3210.30 2 171 2.3E-18 T 14-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily HL41_07720 401ef74a26f8b196d00498163ec72690 252 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 32 156 1.6E-13 T 14-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain HL41_05375 94e6aad3be0f097e8874e7faf2e35de1 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05375 94e6aad3be0f097e8874e7faf2e35de1 131 Gene3D G3DSA:3.30.1490.10 74 131 7.9E-29 T 14-10-2018 HL41_05375 94e6aad3be0f097e8874e7faf2e35de1 131 SUPERFAMILY SSF56047 1 131 2.22E-51 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05375 94e6aad3be0f097e8874e7faf2e35de1 131 Pfam PF00410 Ribosomal protein S8 4 131 2.2E-53 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05375 94e6aad3be0f097e8874e7faf2e35de1 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 1 131 33.113 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05375 94e6aad3be0f097e8874e7faf2e35de1 131 Gene3D G3DSA:3.30.1370.30 1 72 3.1E-28 T 14-10-2018 HL41_01105 08cbff26a674a38b9018105e5662aad5 186 PIRSF PIRSF006806 1 181 2.0E-42 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase HL41_01105 08cbff26a674a38b9018105e5662aad5 186 SUPERFAMILY SSF100950 2 184 1.53E-50 T 14-10-2018 IPR037171 NagB/RpiA transferase-like HL41_01105 08cbff26a674a38b9018105e5662aad5 186 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 178 1.5E-35 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase HL41_01105 08cbff26a674a38b9018105e5662aad5 186 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 178 8.0E-46 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase HL41_01105 08cbff26a674a38b9018105e5662aad5 186 Gene3D G3DSA:3.40.50.10420 1 185 1.5E-54 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily HL41_02600 05b6fcc090d8151c0c695139d209954d 331 SMART SM00962 140 328 3.1E-9 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_02600 05b6fcc090d8151c0c695139d209954d 331 Gene3D G3DSA:1.20.120.1380 113 318 1.3E-28 T 14-10-2018 HL41_02600 05b6fcc090d8151c0c695139d209954d 331 Pfam PF00448 SRP54-type protein, GTPase domain 142 326 4.5E-16 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HL41_02600 05b6fcc090d8151c0c695139d209954d 331 Gene3D G3DSA:3.40.50.300 135 316 1.3E-28 T 14-10-2018 HL41_02600 05b6fcc090d8151c0c695139d209954d 331 SUPERFAMILY SSF52540 138 327 8.54E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_00465 bcde0d23bcf51573921118683dcf45d7 517 Pfam PF03734 L,D-transpeptidase catalytic domain 283 451 9.4E-29 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 HL41_00465 bcde0d23bcf51573921118683dcf45d7 517 Pfam PF01471 Putative peptidoglycan binding domain 203 253 3.1E-9 T 14-10-2018 IPR002477 Peptidoglycan binding-like HL41_00465 bcde0d23bcf51573921118683dcf45d7 517 SUPERFAMILY SSF141523 280 442 1.83E-19 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like HL41_00465 bcde0d23bcf51573921118683dcf45d7 517 SUPERFAMILY SSF47090 184 261 4.55E-13 T 14-10-2018 IPR036365 PGBD-like superfamily HL41_00440 941f947ce35f165abe6f5f8a3c2ff036 171 Gene3D G3DSA:2.30.30.240 91 170 2.8E-10 T 14-10-2018 HL41_00440 941f947ce35f165abe6f5f8a3c2ff036 171 Gene3D G3DSA:2.40.30.60 2 89 5.8E-15 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 HL41_00440 941f947ce35f165abe6f5f8a3c2ff036 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 165 17.982 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HL41_00440 941f947ce35f165abe6f5f8a3c2ff036 171 SUPERFAMILY SSF50346 95 165 3.49E-13 T 14-10-2018 IPR011033 PRC-barrel-like superfamily HL41_00440 941f947ce35f165abe6f5f8a3c2ff036 171 Pfam PF01782 RimM N-terminal domain 5 83 9.0E-13 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 HL41_00440 941f947ce35f165abe6f5f8a3c2ff036 171 SUPERFAMILY SSF50447 3 89 7.06E-11 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily HL41_00440 941f947ce35f165abe6f5f8a3c2ff036 171 Pfam PF05239 PRC-barrel domain 92 165 1.2E-4 T 14-10-2018 IPR027275 PRC-barrel domain HL41_00440 941f947ce35f165abe6f5f8a3c2ff036 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 165 6.6E-37 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HL41_06630 fccbaf466bdd698a80e4d8deb335ba0f 125 Pfam PF08821 CGGC domain 4 115 1.2E-24 T 14-10-2018 IPR014925 Uncharacterised domain CGGC-dom HL41_06630 fccbaf466bdd698a80e4d8deb335ba0f 125 SMART SM01078 3 115 1.4E-13 T 14-10-2018 IPR014925 Uncharacterised domain CGGC-dom HL41_02540 176f5dd2584a2f0654265be41924851f 349 SUPERFAMILY SSF51726 8 342 1.01E-24 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HL41_02540 176f5dd2584a2f0654265be41924851f 349 Gene3D G3DSA:3.20.20.210 2 348 2.8E-23 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 HL41_07805 1d73568f3ccc5a3ae228be80d60edf8f 856 Pfam PF04465 Protein of unknown function (DUF499) 140 664 7.4E-37 T 14-10-2018 IPR007555 Protein of unknown function DUF499 HL41_07805 1d73568f3ccc5a3ae228be80d60edf8f 856 Gene3D G3DSA:3.40.50.300 53 229 4.3E-5 T 14-10-2018 HL41_07340 0e2ac1ed8af2a1eda0299c675be7be0d 323 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 55 224 5.6E-24 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HL41_07340 0e2ac1ed8af2a1eda0299c675be7be0d 323 SUPERFAMILY SSF52518 18 312 2.95E-78 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold HL41_07340 0e2ac1ed8af2a1eda0299c675be7be0d 323 Gene3D G3DSA:3.40.50.970 104 313 1.1E-65 T 14-10-2018 HL41_07340 0e2ac1ed8af2a1eda0299c675be7be0d 323 Gene3D G3DSA:3.40.50.970 7 103 6.1E-14 T 14-10-2018 HL41_02765 d12f3ff402128d7193340bc3064c23c8 238 SUPERFAMILY SSF52540 2 233 1.65E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_02765 d12f3ff402128d7193340bc3064c23c8 238 Pfam PF00005 ABC transporter 18 163 1.1E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HL41_02765 d12f3ff402128d7193340bc3064c23c8 238 Gene3D G3DSA:3.40.50.300 1 238 5.8E-67 T 14-10-2018 HL41_02765 d12f3ff402128d7193340bc3064c23c8 238 SMART SM00382 26 217 4.3E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_02765 d12f3ff402128d7193340bc3064c23c8 238 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 2 238 8.2E-101 T 14-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 HL41_02765 d12f3ff402128d7193340bc3064c23c8 238 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HL41_04400 85d1d2aa21b4d5aee4a9229b17b5009b 116 Pfam PF00872 Transposase, Mutator family 2 110 5.9E-24 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_01390 5b1f341b33aa7d1c806d595680605656 397 Pfam PF01266 FAD dependent oxidoreductase 7 393 1.1E-53 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HL41_01390 5b1f341b33aa7d1c806d595680605656 397 SUPERFAMILY SSF51905 6 218 6.47E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_06210 6e9708b737276ae95f73aa778d375829 241 Gene3D G3DSA:3.20.20.410 1 240 5.2E-76 T 14-10-2018 IPR036520 UPF0759 superfamily HL41_06210 6e9708b737276ae95f73aa778d375829 241 SUPERFAMILY SSF117396 1 238 4.32E-77 T 14-10-2018 IPR036520 UPF0759 superfamily HL41_06210 6e9708b737276ae95f73aa778d375829 241 Pfam PF01904 Protein of unknown function DUF72 20 236 4.6E-61 T 14-10-2018 IPR002763 Protein of unknown function DUF72 HL41_00615 d8732a874af935a32aea50bf082cf933 62 Pfam PF03884 DNA gyrase inhibitor YacG 1 45 6.5E-19 T 14-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 HL41_00615 d8732a874af935a32aea50bf082cf933 62 SUPERFAMILY SSF57716 1 53 1.01E-14 T 14-10-2018 HL41_00615 d8732a874af935a32aea50bf082cf933 62 Gene3D G3DSA:3.30.50.10 1 56 7.5E-19 T 14-10-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 Reactome: R-HSA-383280 HL41_03650 f44d0de57eb785301f6e5b301a72ffdb 71 Pfam PF09723 Zinc ribbon domain 1 40 3.0E-13 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_03650 f44d0de57eb785301f6e5b301a72ffdb 71 SMART SM00834 1 41 6.5E-11 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_03650 f44d0de57eb785301f6e5b301a72ffdb 71 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 47 2.9E-14 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_05080 413149141153e36d4b0fc6d0a558e64e 359 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 126 353 5.7E-56 T 14-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 HL41_05080 413149141153e36d4b0fc6d0a558e64e 359 Pfam PF02163 Peptidase family M50 7 340 2.8E-83 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 HL41_05080 413149141153e36d4b0fc6d0a558e64e 359 Pfam PF13180 PDZ domain 128 190 4.6E-13 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_05080 413149141153e36d4b0fc6d0a558e64e 359 SUPERFAMILY SSF50156 88 192 1.97E-19 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 HL41_05080 413149141153e36d4b0fc6d0a558e64e 359 SMART SM00228 114 183 9.0E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 HL41_05080 413149141153e36d4b0fc6d0a558e64e 359 Gene3D G3DSA:2.30.42.10 124 220 3.9E-21 T 14-10-2018 HL41_03100 c34855a3ef3911ade59b85b073d32447 266 SUPERFAMILY SSF55681 19 189 1.68E-31 T 14-10-2018 HL41_03100 c34855a3ef3911ade59b85b073d32447 266 Gene3D G3DSA:3.30.930.10 16 204 4.1E-32 T 14-10-2018 HL41_03100 c34855a3ef3911ade59b85b073d32447 266 Pfam PF03099 Biotin/lipoate A/B protein ligase family 61 145 9.0E-8 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 HL41_03100 c34855a3ef3911ade59b85b073d32447 266 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 47 262 4.3E-26 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HL41_05355 c1c58fa4953a05f511b8a14d1f4d45a4 61 PIRSF PIRSF002211 1 60 3.0E-30 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05355 c1c58fa4953a05f511b8a14d1f4d45a4 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 21.662 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05355 c1c58fa4953a05f511b8a14d1f4d45a4 61 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 5.3E-20 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HL41_05355 c1c58fa4953a05f511b8a14d1f4d45a4 61 Gene3D G3DSA:3.30.1390.20 1 60 5.2E-28 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily HL41_05355 c1c58fa4953a05f511b8a14d1f4d45a4 61 SUPERFAMILY SSF55129 1 60 3.79E-23 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily HL41_05355 c1c58fa4953a05f511b8a14d1f4d45a4 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.2E-24 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04320 8730d26a8b043fed697e7d6bb6af888b 142 Pfam PF01597 Glycine cleavage H-protein 9 127 1.0E-29 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate HL41_04320 8730d26a8b043fed697e7d6bb6af888b 142 Gene3D G3DSA:2.40.50.100 3 131 3.9E-38 T 14-10-2018 HL41_04320 8730d26a8b043fed697e7d6bb6af888b 142 SUPERFAMILY SSF51230 4 127 1.57E-29 T 14-10-2018 IPR011053 Single hybrid motif HL41_00555 c6bb8203b0185b0da178d4cf55bf2257 254 SUPERFAMILY SSF160527 166 250 1.16E-5 T 14-10-2018 HL41_00555 c6bb8203b0185b0da178d4cf55bf2257 254 Pfam PF02108 Flagellar assembly protein FliH 121 245 9.3E-24 T 14-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE HL41_01170 e9f1a8a881ffd375424ea487862267a5 1224 Pfam PF13109 AsmA-like C-terminal region 1068 1166 5.0E-7 T 14-10-2018 IPR039441 AsmA-like C-terminal region HL41_08860 fbc8fc3a019d0f34c0ca42e3fcb6de32 460 SUPERFAMILY SSF48024 23 132 2.75E-35 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 HL41_08860 fbc8fc3a019d0f34c0ca42e3fcb6de32 460 Pfam PF00772 DnaB-like helicase N terminal domain 23 124 1.7E-32 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HL41_08860 fbc8fc3a019d0f34c0ca42e3fcb6de32 460 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 22 454 1.1E-172 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 HL41_08860 fbc8fc3a019d0f34c0ca42e3fcb6de32 460 Gene3D G3DSA:1.10.860.10 18 177 5.4E-51 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HL41_08860 fbc8fc3a019d0f34c0ca42e3fcb6de32 460 Pfam PF03796 DnaB-like helicase C terminal domain 198 452 5.8E-113 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 HL41_08860 fbc8fc3a019d0f34c0ca42e3fcb6de32 460 SUPERFAMILY SSF52540 196 444 8.42E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_08860 fbc8fc3a019d0f34c0ca42e3fcb6de32 460 Gene3D G3DSA:3.40.50.300 178 457 2.2E-107 T 14-10-2018 HL41_08860 fbc8fc3a019d0f34c0ca42e3fcb6de32 460 SMART SM00382 215 412 1.3E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain HL41_05800 13b4854631bf034c94c0cc7b84c68369 400 SUPERFAMILY SSF103473 11 388 1.1E-34 T 14-10-2018 IPR036259 MFS transporter superfamily HL41_05800 13b4854631bf034c94c0cc7b84c68369 400 Gene3D G3DSA:1.20.1250.20 6 187 4.2E-12 T 14-10-2018 HL41_05800 13b4854631bf034c94c0cc7b84c68369 400 Pfam PF07690 Major Facilitator Superfamily 14 356 6.0E-23 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HL41_05800 13b4854631bf034c94c0cc7b84c68369 400 Gene3D G3DSA:1.20.1250.20 207 394 2.8E-13 T 14-10-2018 HL41_03095 101d7acaa9252b212183d1548cbf0d32 219 SUPERFAMILY SSF51230 17 97 6.15E-6 T 14-10-2018 IPR011053 Single hybrid motif HL41_03095 101d7acaa9252b212183d1548cbf0d32 219 Gene3D G3DSA:2.40.50.100 24 101 2.9E-9 T 14-10-2018 HL41_04130 3e7961447294e16ce9b456a0712b8aa0 189 SUPERFAMILY SSF55144 1 187 4.71E-39 T 14-10-2018 IPR009097 Cyclic phosphodiesterase HL41_04130 3e7961447294e16ce9b456a0712b8aa0 189 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 187 25.079 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 HL41_04130 3e7961447294e16ce9b456a0712b8aa0 189 Gene3D G3DSA:3.90.1140.10 1 188 4.7E-50 T 14-10-2018 HL41_04130 3e7961447294e16ce9b456a0712b8aa0 189 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 186 2.5E-43 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 HL41_04130 3e7961447294e16ce9b456a0712b8aa0 189 Pfam PF13563 2'-5' RNA ligase superfamily 27 169 7.0E-14 T 14-10-2018 HL41_07390 41e8820ee75600c7521bc5065c566c6e 543 Pfam PF13183 4Fe-4S dicluster domain 108 195 9.2E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_07390 41e8820ee75600c7521bc5065c566c6e 543 Pfam PF02754 Cysteine-rich domain 402 503 1.6E-6 T 14-10-2018 IPR004017 Cysteine-rich domain HL41_07390 41e8820ee75600c7521bc5065c566c6e 543 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 181 192 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_07390 41e8820ee75600c7521bc5065c566c6e 543 SUPERFAMILY SSF46548 105 207 1.55E-12 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HL41_02745 992ff41e2f84435582bbf024481a408e 266 Gene3D G3DSA:3.40.1700.10 96 247 8.4E-61 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily HL41_02745 992ff41e2f84435582bbf024481a408e 266 PIRSF PIRSF004793 3 258 4.4E-87 T 14-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 HL41_02745 992ff41e2f84435582bbf024481a408e 266 SUPERFAMILY SSF143597 39 232 9.94E-65 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily HL41_02745 992ff41e2f84435582bbf024481a408e 266 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 111 229 5.9E-44 T 14-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal HL41_02745 992ff41e2f84435582bbf024481a408e 266 Hamap MF_01499 Diadenylate cyclase [dacA]. 3 247 33.336 T 14-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 HL41_02745 992ff41e2f84435582bbf024481a408e 266 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 9 242 6.1E-72 T 14-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 HL41_06640 a8542963057830e0bc41ee85032aedc8 424 Gene3D G3DSA:3.65.10.10 11 419 2.1E-161 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HL41_06640 a8542963057830e0bc41ee85032aedc8 424 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 412 1.7E-92 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HL41_06640 a8542963057830e0bc41ee85032aedc8 424 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 6 422 39.018 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_06640 a8542963057830e0bc41ee85032aedc8 424 Gene3D G3DSA:3.65.10.10 26 233 2.1E-161 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 HL41_06640 a8542963057830e0bc41ee85032aedc8 424 SUPERFAMILY SSF55205 9 421 1.64E-128 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HL41_06640 a8542963057830e0bc41ee85032aedc8 424 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 8 420 4.2E-160 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 HL41_04140 e528e101a7f97d7fe284e69cce7dfd1a 148 Pfam PF04608 Phosphatidylglycerophosphatase A 2 138 4.4E-33 T 14-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 HL41_04140 e528e101a7f97d7fe284e69cce7dfd1a 148 SUPERFAMILY SSF101307 3 141 5.89E-26 T 14-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 HL41_04140 e528e101a7f97d7fe284e69cce7dfd1a 148 PIRSF PIRSF006162 1 145 6.3E-33 T 14-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 HL41_08685 bd280ca6d2ab71d6767cff76b9c88d54 337 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 9 336 24.786 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08685 bd280ca6d2ab71d6767cff76b9c88d54 337 Pfam PF00146 NADH dehydrogenase 16 329 1.4E-118 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08685 bd280ca6d2ab71d6767cff76b9c88d54 337 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 213 226 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08160 c0444420ee9aece115261659d6fdb5cc 396 Pfam PF00149 Calcineurin-like phosphoesterase 1 229 1.1E-15 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HL41_08160 c0444420ee9aece115261659d6fdb5cc 396 SUPERFAMILY SSF56300 1 315 6.38E-43 T 14-10-2018 HL41_08160 c0444420ee9aece115261659d6fdb5cc 396 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 256 1.4E-33 T 14-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 HL41_08160 c0444420ee9aece115261659d6fdb5cc 396 Gene3D G3DSA:3.60.21.10 1 274 9.1E-55 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like HL41_05090 fc327f999f81825be75aa4a26d72680a 328 Gene3D G3DSA:1.10.3720.10 92 314 5.5E-24 T 14-10-2018 IPR035906 MetI-like superfamily HL41_05090 fc327f999f81825be75aa4a26d72680a 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 323 6.6E-44 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HL41_05090 fc327f999f81825be75aa4a26d72680a 328 SUPERFAMILY SSF161098 92 307 3.43E-21 T 14-10-2018 IPR035906 MetI-like superfamily HL41_00165 27d11af9feecc8d498705899b7400c69 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 75 8.2E-33 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HL41_00165 27d11af9feecc8d498705899b7400c69 78 SUPERFAMILY SSF47336 3 76 6.41E-25 T 14-10-2018 IPR036736 ACP-like superfamily HL41_00165 27d11af9feecc8d498705899b7400c69 78 Gene3D G3DSA:1.10.1200.10 1 75 8.3E-29 T 14-10-2018 IPR036736 ACP-like superfamily HL41_00165 27d11af9feecc8d498705899b7400c69 78 Hamap MF_01217 Acyl carrier protein [acpP]. 2 76 21.944 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HL41_00165 27d11af9feecc8d498705899b7400c69 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site HL41_00165 27d11af9feecc8d498705899b7400c69 78 Pfam PF00550 Phosphopantetheine attachment site 5 72 9.1E-17 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain HL41_00165 27d11af9feecc8d498705899b7400c69 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 33 75 3.0E-9 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HL41_05925 45d2c63449033c2ac96d4fe6bcc9e83e 115 ProDom PD052877 ARCHAEL AF0269 3 53 1.0E-11 T 14-10-2018 HL41_05925 45d2c63449033c2ac96d4fe6bcc9e83e 115 SUPERFAMILY SSF75169 1 115 8.48E-10 T 14-10-2018 IPR027396 DsrEFH-like HL41_05925 45d2c63449033c2ac96d4fe6bcc9e83e 115 Gene3D G3DSA:3.40.1260.10 10 115 2.0E-5 T 14-10-2018 IPR027396 DsrEFH-like HL41_02150 1b007c853b587b5caa9265b8862aec05 431 Pfam PF00909 Ammonium Transporter Family 38 429 2.1E-133 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 HL41_02150 1b007c853b587b5caa9265b8862aec05 431 PRINTS PR00342 Rhesus blood group protein signature 132 148 3.1E-6 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 HL41_02150 1b007c853b587b5caa9265b8862aec05 431 PRINTS PR00342 Rhesus blood group protein signature 310 328 3.1E-6 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 HL41_02150 1b007c853b587b5caa9265b8862aec05 431 PRINTS PR00342 Rhesus blood group protein signature 255 277 3.1E-6 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 HL41_02150 1b007c853b587b5caa9265b8862aec05 431 PRINTS PR00342 Rhesus blood group protein signature 224 242 3.1E-6 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 HL41_02150 1b007c853b587b5caa9265b8862aec05 431 ProSitePatterns PS01219 Ammonium transporters signature. 188 213 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 HL41_02150 1b007c853b587b5caa9265b8862aec05 431 SUPERFAMILY SSF111352 32 410 1.96E-132 T 14-10-2018 HL41_02150 1b007c853b587b5caa9265b8862aec05 431 TIGRFAM TIGR00836 amt: ammonium transporter 36 429 6.1E-146 T 14-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 HL41_02150 1b007c853b587b5caa9265b8862aec05 431 Gene3D G3DSA:1.10.3430.10 16 431 3.3E-150 T 14-10-2018 IPR029020 Ammonium/urea transporter HL41_04845 cc5c6b960365de6a7fd9c6328d0368f7 280 SUPERFAMILY SSF52540 1 266 1.46E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_04845 cc5c6b960365de6a7fd9c6328d0368f7 280 SUPERFAMILY SSF54862 45 117 2.09E-17 T 14-10-2018 HL41_04845 cc5c6b960365de6a7fd9c6328d0368f7 280 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 257 9.2E-15 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HL41_04845 cc5c6b960365de6a7fd9c6328d0368f7 280 Gene3D G3DSA:3.30.70.20 63 112 1.3E-11 T 14-10-2018 HL41_04845 cc5c6b960365de6a7fd9c6328d0368f7 280 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HL41_04845 cc5c6b960365de6a7fd9c6328d0368f7 280 Pfam PF13187 4Fe-4S dicluster domain 65 114 2.7E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_06385 64d658ff9f8d52c3152bdc9dc328e021 90 Pfam PF01934 Protein of unknown function DUF86 3 70 1.1E-11 T 14-10-2018 IPR008201 Protein of unknown function DUF86 HL41_06385 64d658ff9f8d52c3152bdc9dc328e021 90 Gene3D G3DSA:1.20.120.580 1 89 2.9E-13 T 14-10-2018 IPR037038 Bsu32300-like superfamily HL41_07615 8f1dfb62b89d98cd6a00704445d4b9fb 298 Pfam PF00809 Pterin binding enzyme 10 225 6.8E-23 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_07615 8f1dfb62b89d98cd6a00704445d4b9fb 298 Gene3D G3DSA:3.20.20.20 1 251 3.4E-72 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_07615 8f1dfb62b89d98cd6a00704445d4b9fb 298 SUPERFAMILY SSF51717 6 250 1.57E-64 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_04075 5b2a532397775d610339adf3aa321834 546 Pfam PF14849 YidC periplasmic domain 79 339 4.1E-31 T 14-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain HL41_04075 5b2a532397775d610339adf3aa321834 546 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 350 540 1.3E-67 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_04075 5b2a532397775d610339adf3aa321834 546 Pfam PF02096 60Kd inner membrane protein 351 540 4.7E-61 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HL41_04075 5b2a532397775d610339adf3aa321834 546 PRINTS PR00701 60kDa inner membrane protein signature 167 187 4.1E-17 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HL41_04075 5b2a532397775d610339adf3aa321834 546 PRINTS PR00701 60kDa inner membrane protein signature 508 531 4.1E-17 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HL41_04075 5b2a532397775d610339adf3aa321834 546 PRINTS PR00701 60kDa inner membrane protein signature 472 494 4.1E-17 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HL41_04075 5b2a532397775d610339adf3aa321834 546 Gene3D G3DSA:2.70.98.90 79 327 1.0E-17 T 14-10-2018 IPR038221 YidC, periplasmic domain superfamily HL41_04075 5b2a532397775d610339adf3aa321834 546 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 3 544 20.081 T 14-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 HL41_04075 5b2a532397775d610339adf3aa321834 546 PRINTS PR01900 YidC translocation/secretion protein signature 497 521 2.8E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HL41_04075 5b2a532397775d610339adf3aa321834 546 PRINTS PR01900 YidC translocation/secretion protein signature 478 493 2.8E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HL41_04075 5b2a532397775d610339adf3aa321834 546 PRINTS PR01900 YidC translocation/secretion protein signature 336 352 2.8E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 HL41_04075 5b2a532397775d610339adf3aa321834 546 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 348 5.2E-45 T 14-10-2018 IPR028053 Membrane insertase YidC, N-terminal HL41_05935 a32f09bf2f44c407f377c39d65c3748f 64 SUPERFAMILY SSF57802 9 61 1.23E-17 T 14-10-2018 HL41_05935 a32f09bf2f44c407f377c39d65c3748f 64 Gene3D G3DSA:2.20.28.10 2 63 1.8E-21 T 14-10-2018 HL41_05935 a32f09bf2f44c407f377c39d65c3748f 64 ProSitePatterns PS00202 Rubredoxin signature. 41 51 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 HL41_05935 a32f09bf2f44c407f377c39d65c3748f 64 Pfam PF00301 Rubredoxin 10 57 1.6E-19 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 HL41_08575 e7e6e856c8cd58d71ff73b077b5044a4 250 Pfam PF04216 Protein involved in formate dehydrogenase formation 117 244 7.5E-17 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 HL41_08575 e7e6e856c8cd58d71ff73b077b5044a4 250 Gene3D G3DSA:3.90.1670.10 65 248 1.6E-25 T 14-10-2018 IPR024064 FdhE-like superfamily HL41_08575 e7e6e856c8cd58d71ff73b077b5044a4 250 SUPERFAMILY SSF144020 12 246 3.01E-30 T 14-10-2018 IPR024064 FdhE-like superfamily HL41_09050 bc07c0e3efdf7044cdc00841a860e496 282 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 27 88 3.9E-11 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HL41_09050 bc07c0e3efdf7044cdc00841a860e496 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 280 2.5E-109 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 HL41_09050 bc07c0e3efdf7044cdc00841a860e496 282 Pfam PF02569 Pantoate-beta-alanine ligase 4 277 7.0E-108 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 HL41_09050 bc07c0e3efdf7044cdc00841a860e496 282 Hamap MF_00158 Pantothenate synthetase [panC]. 3 280 42.029 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 HL41_09050 bc07c0e3efdf7044cdc00841a860e496 282 SUPERFAMILY SSF52374 3 280 8.19E-112 T 14-10-2018 HL41_09050 bc07c0e3efdf7044cdc00841a860e496 282 Gene3D G3DSA:3.30.1300.10 179 278 8.1E-32 T 14-10-2018 HL41_09050 bc07c0e3efdf7044cdc00841a860e496 282 Gene3D G3DSA:3.40.50.620 1 178 5.0E-82 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_01625 82d70c3aaa7d5d3398a4a02afcaf38e3 351 Pfam PF02665 Nitrate reductase gamma subunit 120 279 1.0E-19 T 14-10-2018 IPR023234 NarG-like domain HL41_01625 82d70c3aaa7d5d3398a4a02afcaf38e3 351 Gene3D G3DSA:1.20.950.20 89 284 1.6E-20 T 14-10-2018 HL41_01625 82d70c3aaa7d5d3398a4a02afcaf38e3 351 SUPERFAMILY SSF103501 27 294 1.83E-47 T 14-10-2018 IPR036197 NarG-like superfamily HL41_02820 16525a6b47b06d760f5864ad04008d6e 256 SUPERFAMILY SSF56281 10 244 2.75E-34 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_02820 16525a6b47b06d760f5864ad04008d6e 256 Pfam PF00753 Metallo-beta-lactamase superfamily 32 226 5.4E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_02820 16525a6b47b06d760f5864ad04008d6e 256 Gene3D G3DSA:3.60.15.10 8 248 4.8E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_02820 16525a6b47b06d760f5864ad04008d6e 256 SMART SM00849 35 226 1.3E-19 T 14-10-2018 IPR001279 Metallo-beta-lactamase HL41_08205 54f517b83aaf681edf8069a36c3cbc2a 418 SMART SM00729 168 392 4.2E-45 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_08205 54f517b83aaf681edf8069a36c3cbc2a 418 Gene3D G3DSA:3.80.30.20 167 393 2.5E-44 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HL41_08205 54f517b83aaf681edf8069a36c3cbc2a 418 SUPERFAMILY SSF102114 167 379 1.7E-42 T 14-10-2018 HL41_08205 54f517b83aaf681edf8069a36c3cbc2a 418 Gene3D G3DSA:3.40.50.280 1 136 2.5E-24 T 14-10-2018 HL41_08205 54f517b83aaf681edf8069a36c3cbc2a 418 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 2 402 6.7E-139 T 14-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type HL41_08205 54f517b83aaf681edf8069a36c3cbc2a 418 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 172 192 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 HL41_08205 54f517b83aaf681edf8069a36c3cbc2a 418 Pfam PF02310 B12 binding domain 43 120 6.6E-9 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 HL41_08205 54f517b83aaf681edf8069a36c3cbc2a 418 Pfam PF04055 Radical SAM superfamily 173 348 2.1E-23 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_08205 54f517b83aaf681edf8069a36c3cbc2a 418 SUPERFAMILY SSF51366 65 111 6.73E-5 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HL41_02440 849c3803c0cf9679e3466a7e3ddad740 117 Pfam PF07498 Rho termination factor, N-terminal domain 19 56 4.2E-6 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 HL41_02440 849c3803c0cf9679e3466a7e3ddad740 117 SMART SM00959 18 61 1.7E-4 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 HL41_04310 f1132b915470ef5a341650dc237137e1 379 SUPERFAMILY SSF111249 2 362 3.01E-172 T 14-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 HL41_04310 f1132b915470ef5a341650dc237137e1 379 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 362 59.009 T 14-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 HL41_04310 f1132b915470ef5a341650dc237137e1 379 Pfam PF01950 Fructose-1,6-bisphosphatase 2 362 6.4E-185 T 14-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 HL41_04310 f1132b915470ef5a341650dc237137e1 379 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 2 361 3.0E-164 T 14-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 HL41_04310 f1132b915470ef5a341650dc237137e1 379 PIRSF PIRSF015647 1 373 2.3E-185 T 14-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 HL41_03990 3c16cff7e6b9e2259d7fecc982e6fa87 153 SUPERFAMILY SSF52218 1 135 2.1E-6 T 14-10-2018 IPR029039 Flavoprotein-like superfamily HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 149 298 7.8E-52 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 5.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 5.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 5.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 217 227 5.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 5.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 141 9.0E-50 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 Gene3D G3DSA:3.40.50.1370 131 287 1.2E-113 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 301 76.293 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 300 1.5E-120 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 Gene3D G3DSA:3.40.50.1370 5 297 1.2E-113 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 SUPERFAMILY SSF53671 2 301 1.44E-106 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 9.0E-28 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 9.0E-28 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 9.0E-28 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_02245 f6ac6e9a0e0fb6949c10613077290fef 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 9.0E-28 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HL41_08010 64e4961a9eac70d81a7a1b4f890ce91a 274 SUPERFAMILY SSF141868 10 249 1.57E-52 T 14-10-2018 IPR035919 EAL domain superfamily HL41_08010 64e4961a9eac70d81a7a1b4f890ce91a 274 Pfam PF00563 EAL domain 10 236 3.3E-46 T 14-10-2018 IPR001633 EAL domain HL41_08010 64e4961a9eac70d81a7a1b4f890ce91a 274 Gene3D G3DSA:3.20.20.450 4 243 2.5E-51 T 14-10-2018 IPR035919 EAL domain superfamily HL41_08010 64e4961a9eac70d81a7a1b4f890ce91a 274 SMART SM00052 5 241 5.1E-26 T 14-10-2018 IPR001633 EAL domain HL41_06950 95e9bd0c30cdfd996ce00bfbf219dd87 401 Pfam PF00872 Transposase, Mutator family 6 357 7.3E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_03325 95e9bd0c30cdfd996ce00bfbf219dd87 401 Pfam PF00872 Transposase, Mutator family 6 357 7.3E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_08825 95e9bd0c30cdfd996ce00bfbf219dd87 401 Pfam PF00872 Transposase, Mutator family 6 357 7.3E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_07580 95e9bd0c30cdfd996ce00bfbf219dd87 401 Pfam PF00872 Transposase, Mutator family 6 357 7.3E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_07115 95e9bd0c30cdfd996ce00bfbf219dd87 401 Pfam PF00872 Transposase, Mutator family 6 357 7.3E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_02810 95e9bd0c30cdfd996ce00bfbf219dd87 401 Pfam PF00872 Transposase, Mutator family 6 357 7.3E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_08105 95e9bd0c30cdfd996ce00bfbf219dd87 401 Pfam PF00872 Transposase, Mutator family 6 357 7.3E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_06400 95e9bd0c30cdfd996ce00bfbf219dd87 401 Pfam PF00872 Transposase, Mutator family 6 357 7.3E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_06570 95e9bd0c30cdfd996ce00bfbf219dd87 401 Pfam PF00872 Transposase, Mutator family 6 357 7.3E-64 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HL41_03200 a7240c46d780933b8600eebd69893b42 405 Pfam PF02687 FtsX-like permease family 313 398 2.9E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HL41_03200 a7240c46d780933b8600eebd69893b42 405 Pfam PF12704 MacB-like periplasmic core domain 26 243 5.8E-26 T 14-10-2018 IPR025857 MacB-like periplasmic core domain HL41_02785 ddf6f583264531c5718355344092e361 273 Pfam PF01972 Serine dehydrogenase proteinase 6 271 2.2E-114 T 14-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 HL41_02785 ddf6f583264531c5718355344092e361 273 SUPERFAMILY SSF52096 56 235 3.39E-26 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily HL41_02785 ddf6f583264531c5718355344092e361 273 Gene3D G3DSA:3.90.226.10 58 251 4.7E-22 T 14-10-2018 HL41_03180 691efb6ef3cf244f8eb8c22d1362b057 461 Gene3D G3DSA:1.20.1740.10 16 461 4.1E-113 T 14-10-2018 HL41_03180 691efb6ef3cf244f8eb8c22d1362b057 461 Pfam PF13520 Amino acid permease 22 438 6.7E-50 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HL41_03180 691efb6ef3cf244f8eb8c22d1362b057 461 PIRSF PIRSF006060 1 460 1.1E-85 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 9 329 30.691 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 21 89 2.3E-13 T 14-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 271 299 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 Gene3D G3DSA:3.40.1390.10 1 96 5.6E-18 T 14-10-2018 HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 110 143 0.001 T 14-10-2018 IPR001451 Hexapeptide repeat HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 227 261 3.1E-6 T 14-10-2018 IPR001451 Hexapeptide repeat HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 146 179 1.3E-9 T 14-10-2018 IPR001451 Hexapeptide repeat HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 Gene3D G3DSA:2.160.10.10 100 312 8.0E-58 T 14-10-2018 HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 9 331 4.6E-94 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 HL41_03440 66bc87c9e35f6bde8257ad388c3c023a 340 SUPERFAMILY SSF51161 33 318 2.28E-69 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily HL41_02545 8ed7967d8097489966f582413363c510 199 SMART SM00507 94 148 3.0E-14 T 14-10-2018 IPR003615 HNH nuclease HL41_02545 8ed7967d8097489966f582413363c510 199 Gene3D G3DSA:3.30.40.60 87 183 5.4E-23 T 14-10-2018 HL41_02545 8ed7967d8097489966f582413363c510 199 Pfam PF14279 HNH endonuclease 107 159 3.0E-18 T 14-10-2018 IPR029471 HNH endonuclease 5 HL41_06090 213d10511f673c9c9dc5c5a2142e12b6 482 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 125 144 3.6E-5 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06090 213d10511f673c9c9dc5c5a2142e12b6 482 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 370 396 3.6E-5 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06090 213d10511f673c9c9dc5c5a2142e12b6 482 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 157 181 3.6E-5 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06090 213d10511f673c9c9dc5c5a2142e12b6 482 Pfam PF00361 Proton-conducting membrane transporter 119 413 1.8E-61 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_06090 213d10511f673c9c9dc5c5a2142e12b6 482 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 463 1.3E-105 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 HL41_06090 213d10511f673c9c9dc5c5a2142e12b6 482 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 5 464 16.161 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 HL41_06190 15c34d3a682c0c3e0592181b157c9d3a 149 Gene3D G3DSA:2.40.280.10 1 126 3.9E-50 T 14-10-2018 IPR023620 Small protein B HL41_06190 15c34d3a682c0c3e0592181b157c9d3a 149 Hamap MF_00023 SsrA-binding protein [smpB]. 1 149 68.694 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 HL41_06190 15c34d3a682c0c3e0592181b157c9d3a 149 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 4 129 4.0E-41 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 HL41_06190 15c34d3a682c0c3e0592181b157c9d3a 149 Pfam PF01668 SmpB protein 5 147 4.6E-60 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 HL41_06190 15c34d3a682c0c3e0592181b157c9d3a 149 SUPERFAMILY SSF74982 2 129 3.14E-48 T 14-10-2018 IPR023620 Small protein B HL41_06190 15c34d3a682c0c3e0592181b157c9d3a 149 TIGRFAM TIGR00086 smpB: SsrA-binding protein 4 147 2.8E-56 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 HL41_06190 15c34d3a682c0c3e0592181b157c9d3a 149 ProSitePatterns PS01317 SsrA-binding protein. 22 34 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site HL41_02860 8d8730cea14b90aa4caa4bd1eb73314d 149 Pfam PF12276 Protein of unknown function (DUF3617) 1 145 7.1E-14 T 14-10-2018 IPR022061 Protein of unknown function DUF3617 HL41_04425 5b23b2d15d589adba313e5b81665dd85 287 Hamap MF_00188 Protease HtpX [htpX]. 4 282 29.639 T 14-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 HL41_04425 5b23b2d15d589adba313e5b81665dd85 287 Pfam PF01435 Peptidase family M48 65 280 9.6E-39 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HL41_04425 5b23b2d15d589adba313e5b81665dd85 287 Gene3D G3DSA:3.30.2010.10 57 148 9.0E-31 T 14-10-2018 HL41_08535 4449e7da2daff18b1b386a7be7e7805b 599 Pfam PF02705 K+ potassium transporter 6 534 8.1E-161 T 14-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 4.8E-39 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 4.8E-39 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 4.8E-39 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 Pfam PF00453 Ribosomal protein L20 3 109 2.9E-48 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 SUPERFAMILY SSF74731 2 115 3.01E-48 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 70 3.0E-6 T 14-10-2018 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 Gene3D G3DSA:1.10.720.90 2 55 1.0E-24 T 14-10-2018 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.223 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 5.7E-48 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_05970 ed567595ecb793c87d5e40d14d5f57f4 118 Gene3D G3DSA:1.10.1900.20 56 118 1.9E-28 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_03140 5713586460c4ba598abd9c8a1d3f548e 247 SUPERFAMILY SSF53448 4 237 1.58E-62 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_03140 5713586460c4ba598abd9c8a1d3f548e 247 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 234 1.9E-78 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 HL41_03140 5713586460c4ba598abd9c8a1d3f548e 247 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 241 40.147 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 HL41_03140 5713586460c4ba598abd9c8a1d3f548e 247 Pfam PF02348 Cytidylyltransferase 4 215 4.3E-55 T 14-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 HL41_03140 5713586460c4ba598abd9c8a1d3f548e 247 Gene3D G3DSA:3.90.550.10 1 244 1.2E-86 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases HL41_02435 e63d6b44ec96b1c28f9d3ccf3f6648af 295 ProSitePatterns PS01057 SAICAR synthetase signature 1. 107 121 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_02435 e63d6b44ec96b1c28f9d3ccf3f6648af 295 Gene3D G3DSA:3.30.470.20 106 249 4.6E-66 T 14-10-2018 HL41_02435 e63d6b44ec96b1c28f9d3ccf3f6648af 295 Gene3D G3DSA:3.30.200.20 4 105 9.0E-36 T 14-10-2018 HL41_02435 e63d6b44ec96b1c28f9d3ccf3f6648af 295 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 292 27.539 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_02435 e63d6b44ec96b1c28f9d3ccf3f6648af 295 SUPERFAMILY SSF56104 5 294 2.78E-111 T 14-10-2018 HL41_02435 e63d6b44ec96b1c28f9d3ccf3f6648af 295 ProSitePatterns PS01058 SAICAR synthetase signature 2. 206 214 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_02435 e63d6b44ec96b1c28f9d3ccf3f6648af 295 Pfam PF01259 SAICAR synthetase 16 266 9.4E-106 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HL41_02435 e63d6b44ec96b1c28f9d3ccf3f6648af 295 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 12 292 2.0E-80 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 HL41_08645 23fa0e63c2e61579e0697960c90e1cac 398 Pfam PF03916 Polysulphide reductase, NrfD 57 354 8.0E-18 T 14-10-2018 IPR005614 NrfD family HL41_07395 7444385aaf97046332bdb7985e2b8259 407 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 241 268 9.4E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_07395 7444385aaf97046332bdb7985e2b8259 407 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 270 299 9.4E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 HL41_07395 7444385aaf97046332bdb7985e2b8259 407 SUPERFAMILY SSF58104 96 404 4.71E-65 T 14-10-2018 HL41_07395 7444385aaf97046332bdb7985e2b8259 407 SMART SM00283 143 404 2.4E-55 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_07395 7444385aaf97046332bdb7985e2b8259 407 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 225 370 1.1E-44 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 HL41_07395 7444385aaf97046332bdb7985e2b8259 407 Gene3D G3DSA:1.10.287.950 116 406 3.5E-63 T 14-10-2018 HL41_08760 6d2368493a5a85b03c266343a83fd409 336 SUPERFAMILY SSF55326 5 150 3.74E-29 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_08760 6d2368493a5a85b03c266343a83fd409 336 Gene3D G3DSA:3.90.650.10 154 336 1.5E-56 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_08760 6d2368493a5a85b03c266343a83fd409 336 Gene3D G3DSA:3.30.1330.10 9 152 1.5E-47 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily HL41_08760 6d2368493a5a85b03c266343a83fd409 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 38 150 2.1E-15 T 14-10-2018 IPR016188 PurM-like, N-terminal domain HL41_08760 6d2368493a5a85b03c266343a83fd409 336 PIRSF PIRSF005644 1 336 1.5E-117 T 14-10-2018 IPR011854 Carbamoyl dehydratase HypE HL41_08760 6d2368493a5a85b03c266343a83fd409 336 SUPERFAMILY SSF56042 156 332 1.24E-43 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily HL41_08760 6d2368493a5a85b03c266343a83fd409 336 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 6 336 1.5E-133 T 14-10-2018 IPR011854 Carbamoyl dehydratase HypE HL41_08760 6d2368493a5a85b03c266343a83fd409 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 161 306 2.2E-28 T 14-10-2018 IPR010918 PurM-like, C-terminal domain HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 SMART SM01228 545 616 2.6E-40 T 14-10-2018 HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 Pfam PF13932 GidA associated domain 402 614 3.8E-78 T 14-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 622 42.405 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 Gene3D G3DSA:1.10.10.1800 461 557 1.3E-19 T 14-10-2018 HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 Pfam PF01134 Glucose inhibited division protein A 8 400 1.6E-161 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 SUPERFAMILY SSF51905 6 262 2.66E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 621 2.1E-270 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 Gene3D G3DSA:1.10.150.570 568 621 4.0E-21 T 14-10-2018 HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 Gene3D G3DSA:3.50.50.60 1 220 3.0E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_01855 2a712c0c3c88f0181201d7355e825aaf 622 Gene3D G3DSA:3.50.50.60 307 459 9.0E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily HL41_03765 0f55eec94fc0aabfe5176b28718e141c 365 TIGRFAM TIGR04112 seleno_YedE: putative selenium metabolism protein, YedE family 14 357 5.4E-147 T 14-10-2018 IPR026366 Putative selenium metabolism protein, YedE family HL41_03765 0f55eec94fc0aabfe5176b28718e141c 365 Pfam PF04143 Sulphur transport 222 333 3.0E-10 T 14-10-2018 IPR007272 Sulphur transport domain HL41_08790 075eac4057a516278366d742f17bc356 341 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_08790 075eac4057a516278366d742f17bc356 341 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 33 7.9E-6 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site HL41_05485 1ab30d2689f427a8dbb83705794c86c4 356 Gene3D G3DSA:3.30.360.10 131 338 1.4E-89 T 14-10-2018 HL41_05485 1ab30d2689f427a8dbb83705794c86c4 356 Gene3D G3DSA:3.40.50.720 5 316 1.4E-89 T 14-10-2018 HL41_05485 1ab30d2689f427a8dbb83705794c86c4 356 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 236 5.2E-12 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 HL41_05485 1ab30d2689f427a8dbb83705794c86c4 356 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 119 3.6E-27 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 HL41_05485 1ab30d2689f427a8dbb83705794c86c4 356 SUPERFAMILY SSF55347 131 275 1.64E-32 T 14-10-2018 HL41_05485 1ab30d2689f427a8dbb83705794c86c4 356 SUPERFAMILY SSF51735 2 181 1.51E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_05595 a0e1b0567b29058bcbbbb3f22093556f 252 Gene3D G3DSA:3.40.50.300 3 252 1.5E-47 T 14-10-2018 HL41_05595 a0e1b0567b29058bcbbbb3f22093556f 252 PIRSF PIRSF005647 3 252 2.0E-57 T 14-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type HL41_05595 a0e1b0567b29058bcbbbb3f22093556f 252 SUPERFAMILY SSF52540 4 251 1.15E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05595 a0e1b0567b29058bcbbbb3f22093556f 252 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 9 227 4.4E-13 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HL41_06235 a727ebd13ca6ff1bff6dbb27fee1e132 107 PRINTS PR00421 Thioredoxin family signature 70 81 1.4E-9 T 14-10-2018 HL41_06235 a727ebd13ca6ff1bff6dbb27fee1e132 107 PRINTS PR00421 Thioredoxin family signature 22 30 1.4E-9 T 14-10-2018 HL41_06235 a727ebd13ca6ff1bff6dbb27fee1e132 107 PRINTS PR00421 Thioredoxin family signature 30 39 1.4E-9 T 14-10-2018 HL41_06235 a727ebd13ca6ff1bff6dbb27fee1e132 107 Pfam PF00085 Thioredoxin 5 104 1.2E-32 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 HL41_06235 a727ebd13ca6ff1bff6dbb27fee1e132 107 SUPERFAMILY SSF52833 2 106 2.6E-40 T 14-10-2018 IPR036249 Thioredoxin-like superfamily HL41_06235 a727ebd13ca6ff1bff6dbb27fee1e132 107 Gene3D G3DSA:3.40.30.10 4 107 9.6E-36 T 14-10-2018 HL41_06235 a727ebd13ca6ff1bff6dbb27fee1e132 107 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 105 1.2E-38 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HL41_06235 a727ebd13ca6ff1bff6dbb27fee1e132 107 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 HL41_06235 a727ebd13ca6ff1bff6dbb27fee1e132 107 PIRSF PIRSF000077 1 106 1.3E-43 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HL41_05515 629d09b6774cf6d57351471a9fd05c0e 302 SUPERFAMILY SSF53335 36 300 5.23E-52 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_05515 629d09b6774cf6d57351471a9fd05c0e 302 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 19 301 27.414 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HL41_05515 629d09b6774cf6d57351471a9fd05c0e 302 Gene3D G3DSA:3.40.50.150 68 302 4.9E-51 T 14-10-2018 HL41_05515 629d09b6774cf6d57351471a9fd05c0e 302 Pfam PF01564 Spermine/spermidine synthase domain 72 260 1.2E-29 T 14-10-2018 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 PRINTS PR00974 Ribosomal protein S18 family signature 52 66 2.6E-13 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 PRINTS PR00974 Ribosomal protein S18 family signature 44 51 2.6E-13 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 PRINTS PR00974 Ribosomal protein S18 family signature 34 44 2.6E-13 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 PRINTS PR00974 Ribosomal protein S18 family signature 66 76 2.6E-13 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 27 79 9.0E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 Pfam PF01084 Ribosomal protein S18 26 74 3.6E-25 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 8 79 20.237 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 TIGRFAM TIGR00165 S18: ribosomal protein bS18 11 78 1.2E-27 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 Gene3D G3DSA:4.10.640.10 2 81 4.3E-28 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08850 3b4f8850f97773c93e636f145624cd28 83 SUPERFAMILY SSF46911 8 78 1.57E-28 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HL41_08090 00f14f0c2a23455f4189a04e06e35840 795 Gene3D G3DSA:1.25.40.10 3 93 1.7E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_08090 00f14f0c2a23455f4189a04e06e35840 795 SUPERFAMILY SSF48452 6 83 8.93E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_08090 00f14f0c2a23455f4189a04e06e35840 795 Pfam PF14559 Tetratricopeptide repeat 14 77 2.3E-6 T 14-10-2018 HL41_08090 00f14f0c2a23455f4189a04e06e35840 795 SUPERFAMILY SSF51445 117 478 5.69E-12 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily HL41_08090 00f14f0c2a23455f4189a04e06e35840 795 SMART SM00028 3 36 16.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_08090 00f14f0c2a23455f4189a04e06e35840 795 SMART SM00028 37 70 1.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HL41_03860 4b72eef836585e71f838a3f2a737a1d4 245 Gene3D G3DSA:3.90.1560.10 2 232 6.0E-55 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 HL41_03860 4b72eef836585e71f838a3f2a737a1d4 245 Pfam PF04029 2-phosphosulpholactate phosphatase 15 230 5.5E-50 T 14-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 HL41_03860 4b72eef836585e71f838a3f2a737a1d4 245 SUPERFAMILY SSF142823 3 230 3.27E-46 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 5 795 0.0 T 14-10-2018 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Gene3D G3DSA:1.10.268.10 366 454 2.5E-210 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 SUPERFAMILY SSF56719 26 484 8.5E-179 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 SUPERFAMILY SSF101904 499 798 8.24E-71 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 SMART SM00434 7 461 3.0E-269 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Gene3D G3DSA:3.30.1360.40 232 329 2.5E-210 T 14-10-2018 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 468 2.0E-159 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Gene3D G3DSA:3.90.199.10 28 483 2.5E-210 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 701 736 1.4E-9 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 650 696 3.7E-8 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 752 797 1.9E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 504 530 3.6E-4 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 604 640 4.4E-6 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HL41_07185 eed5464f5f0d20b45dca73a663963d3b 803 Gene3D G3DSA:2.120.10.90 497 798 1.5E-79 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal HL41_06290 cc6e52b0b504f56b9857f0e90a84d7ed 386 Gene3D G3DSA:3.40.50.2000 215 375 1.0E-20 T 14-10-2018 HL41_06290 cc6e52b0b504f56b9857f0e90a84d7ed 386 Pfam PF13692 Glycosyl transferases group 1 224 355 1.7E-22 T 14-10-2018 HL41_06290 cc6e52b0b504f56b9857f0e90a84d7ed 386 SUPERFAMILY SSF53756 10 386 1.76E-29 T 14-10-2018 HL41_06310 e6bcdc95941b396f8415371acacef533 369 Gene3D G3DSA:3.40.50.2000 20 193 5.5E-7 T 14-10-2018 HL41_06310 e6bcdc95941b396f8415371acacef533 369 Gene3D G3DSA:3.40.50.2000 194 341 5.8E-24 T 14-10-2018 HL41_06310 e6bcdc95941b396f8415371acacef533 369 SUPERFAMILY SSF53756 22 366 9.42E-16 T 14-10-2018 HL41_03490 e4692d0c98db23c6c2cff15433744a90 526 Gene3D G3DSA:3.80.30.20 209 426 2.3E-21 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe HL41_03490 e4692d0c98db23c6c2cff15433744a90 526 SMART SM00729 210 416 5.1E-28 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 HL41_03490 e4692d0c98db23c6c2cff15433744a90 526 Pfam PF04055 Radical SAM superfamily 214 370 8.3E-18 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_03490 e4692d0c98db23c6c2cff15433744a90 526 SUPERFAMILY SSF102114 211 419 3.53E-31 T 14-10-2018 HL41_05095 68a9f34854d0fbcdc984169eac2cbb32 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 274 3.3E-31 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 HL41_05095 68a9f34854d0fbcdc984169eac2cbb32 276 SUPERFAMILY SSF161098 68 255 1.23E-25 T 14-10-2018 IPR035906 MetI-like superfamily HL41_05095 68a9f34854d0fbcdc984169eac2cbb32 276 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 50 2.0E-11 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HL41_05095 68a9f34854d0fbcdc984169eac2cbb32 276 Gene3D G3DSA:1.10.3720.10 63 275 8.5E-21 T 14-10-2018 IPR035906 MetI-like superfamily HL41_07235 3b47ee9dbbe1fe78775ed303f73969a7 206 Pfam PF02581 Thiamine monophosphate synthase 6 187 6.4E-54 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HL41_07235 3b47ee9dbbe1fe78775ed303f73969a7 206 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 6 199 5.6E-56 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HL41_07235 3b47ee9dbbe1fe78775ed303f73969a7 206 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 3 206 24.738 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HL41_07235 3b47ee9dbbe1fe78775ed303f73969a7 206 SUPERFAMILY SSF51391 3 204 2.75E-59 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HL41_07235 3b47ee9dbbe1fe78775ed303f73969a7 206 Gene3D G3DSA:3.20.20.70 3 206 2.1E-58 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_07460 7bf52d9bb842a03e824304cf54d7bba7 226 Gene3D G3DSA:3.40.50.450 25 224 5.4E-72 T 14-10-2018 HL41_07460 7bf52d9bb842a03e824304cf54d7bba7 226 Pfam PF03641 Possible lysine decarboxylase 90 220 1.4E-34 T 14-10-2018 IPR031100 LOG family HL41_07460 7bf52d9bb842a03e824304cf54d7bba7 226 SUPERFAMILY SSF102405 19 221 4.88E-63 T 14-10-2018 HL41_07460 7bf52d9bb842a03e824304cf54d7bba7 226 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 49 223 2.4E-49 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG HL41_05840 cd3369ecb4acd19fc86bbae0f971fa32 249 Gene3D G3DSA:3.30.70.980 134 204 5.0E-57 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HL41_05840 cd3369ecb4acd19fc86bbae0f971fa32 249 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 36.11 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HL41_05840 cd3369ecb4acd19fc86bbae0f971fa32 249 SUPERFAMILY SSF75625 3 247 1.44E-93 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HL41_05840 cd3369ecb4acd19fc86bbae0f971fa32 249 Gene3D G3DSA:1.10.10.200 1 82 6.8E-36 T 14-10-2018 IPR017856 Integrase-like, N-terminal HL41_05840 cd3369ecb4acd19fc86bbae0f971fa32 249 Gene3D G3DSA:3.30.70.980 85 236 5.0E-57 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HL41_05840 cd3369ecb4acd19fc86bbae0f971fa32 249 Pfam PF01709 Transcriptional regulator 5 237 2.1E-96 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HL41_05840 cd3369ecb4acd19fc86bbae0f971fa32 249 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 5.4E-98 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HL41_05040 c5de6cc114c91d49739c06c6c80e0f01 221 Pfam PF00037 4Fe-4S binding domain 41 60 1.7E-4 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_05040 c5de6cc114c91d49739c06c6c80e0f01 221 Pfam PF12837 4Fe-4S binding domain 6 29 8.6E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_05040 c5de6cc114c91d49739c06c6c80e0f01 221 Gene3D G3DSA:3.30.70.20 6 62 1.2E-11 T 14-10-2018 HL41_05040 c5de6cc114c91d49739c06c6c80e0f01 221 SUPERFAMILY SSF54862 4 72 1.77E-17 T 14-10-2018 HL41_00360 abcbc807e816c11f12c9ff776d45de7e 195 Pfam PF01965 DJ-1/PfpI family 4 187 9.9E-54 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 HL41_00360 abcbc807e816c11f12c9ff776d45de7e 195 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 190 5.6E-61 T 14-10-2018 IPR006286 Deglycase PfpI HL41_00360 abcbc807e816c11f12c9ff776d45de7e 195 SUPERFAMILY SSF52317 4 190 6.39E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_00360 abcbc807e816c11f12c9ff776d45de7e 195 Gene3D G3DSA:3.40.50.880 2 194 1.5E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like HL41_04315 f322a8d39b3653979934683846442601 98 Gene3D G3DSA:3.40.1690.10 7 87 8.7E-27 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HL41_04315 f322a8d39b3653979934683846442601 98 SUPERFAMILY SSF160544 5 85 7.32E-24 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HL41_04315 f322a8d39b3653979934683846442601 98 Pfam PF01312 FlhB HrpN YscU SpaS Family 5 80 3.7E-22 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HL41_08715 72a89f3fef17c54cd4be60d56c39f605 592 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 290 309 8.6E-5 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08715 72a89f3fef17c54cd4be60d56c39f605 592 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 211 235 8.6E-5 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08715 72a89f3fef17c54cd4be60d56c39f605 592 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 147 171 8.6E-5 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_08715 72a89f3fef17c54cd4be60d56c39f605 592 Pfam PF00361 Proton-conducting membrane transporter 111 383 6.9E-48 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_07760 39ffcf73f2a7423938dbc64a563739aa 87 Gene3D G3DSA:3.30.70.240 1 65 1.1E-32 T 14-10-2018 HL41_07760 39ffcf73f2a7423938dbc64a563739aa 87 SUPERFAMILY SSF143430 1 81 3.4E-29 T 14-10-2018 HL41_07760 39ffcf73f2a7423938dbc64a563739aa 87 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 86 16.285 T 14-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HL41_07760 39ffcf73f2a7423938dbc64a563739aa 87 Pfam PF09827 CRISPR associated protein Cas2 1 70 1.1E-23 T 14-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 HL41_07760 39ffcf73f2a7423938dbc64a563739aa 87 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 82 9.4E-16 T 14-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HL41_07760 39ffcf73f2a7423938dbc64a563739aa 87 PIRSF PIRSF032582 1 87 8.2E-19 T 14-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HL41_05320 0bfee9e04e6ca242846494ee1cdab6ba 123 PIRSF PIRSF002134 1 123 3.7E-47 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05320 0bfee9e04e6ca242846494ee1cdab6ba 123 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 7.1E-53 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05320 0bfee9e04e6ca242846494ee1cdab6ba 123 Pfam PF00416 Ribosomal protein S13/S18 4 109 7.1E-35 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05320 0bfee9e04e6ca242846494ee1cdab6ba 123 SUPERFAMILY SSF46946 4 121 5.1E-48 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 HL41_05320 0bfee9e04e6ca242846494ee1cdab6ba 123 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 14-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05320 0bfee9e04e6ca242846494ee1cdab6ba 123 Gene3D G3DSA:1.10.8.50 1 72 1.1E-30 T 14-10-2018 HL41_05320 0bfee9e04e6ca242846494ee1cdab6ba 123 Gene3D G3DSA:4.10.910.10 73 123 3.8E-24 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_05320 0bfee9e04e6ca242846494ee1cdab6ba 123 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 28.111 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HL41_03725 974359eff89be80e9cb10c4b3042e1ed 185 PIRSF PIRSF005785 1 182 5.5E-48 T 14-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 HL41_03725 974359eff89be80e9cb10c4b3042e1ed 185 Pfam PF07998 Peptidase family M54 45 174 7.7E-25 T 14-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 HL41_03725 974359eff89be80e9cb10c4b3042e1ed 185 Gene3D G3DSA:3.40.390.10 3 174 2.7E-48 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 HL41_03725 974359eff89be80e9cb10c4b3042e1ed 185 SUPERFAMILY SSF55486 46 169 1.09E-13 T 14-10-2018 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 SUPERFAMILY SSF53623 82 311 8.5E-62 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 Pfam PF08245 Mur ligase middle domain 91 292 7.3E-39 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 Gene3D G3DSA:3.40.1190.10 82 317 4.9E-67 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 89 112 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 Gene3D G3DSA:3.90.190.20 321 473 3.4E-59 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 400 2.5E-20 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 2 465 2.8E-152 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 SUPERFAMILY SSF53244 316 468 2.09E-48 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 Pfam PF01225 Mur ligase family, catalytic domain 3 78 5.6E-10 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 466 31.323 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 Gene3D G3DSA:3.40.1390.10 1 81 3.0E-17 T 14-10-2018 HL41_04815 dbf3f7746dc44cf32ecacd265ba905e9 473 SUPERFAMILY SSF63418 3 82 2.09E-16 T 14-10-2018 IPR035911 MurE/MurF, N-terminal HL41_09040 c9270b519eec92e89eb08677eef8c5f6 106 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 10 98 7.3E-14 T 14-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 HL41_09040 c9270b519eec92e89eb08677eef8c5f6 106 Pfam PF04316 Anti-sigma-28 factor, FlgM 48 98 1.9E-13 T 14-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal HL41_09040 c9270b519eec92e89eb08677eef8c5f6 106 SUPERFAMILY SSF101498 28 99 6.93E-13 T 14-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily HL41_02480 916e52eb6ec15976a066aab86288153c 250 Pfam PF10670 Domain of unknown function (DUF4198) 8 216 2.8E-49 T 14-10-2018 IPR019613 Protein of unknown function DUF4198 HL41_02585 ed6c57ec24d3c538dca9a6859903e797 127 Gene3D G3DSA:3.40.50.2300 2 126 8.9E-40 T 14-10-2018 HL41_02585 ed6c57ec24d3c538dca9a6859903e797 127 SMART SM00448 7 121 2.4E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_02585 ed6c57ec24d3c538dca9a6859903e797 127 SUPERFAMILY SSF52172 6 126 3.84E-39 T 14-10-2018 IPR011006 CheY-like superfamily HL41_02585 ed6c57ec24d3c538dca9a6859903e797 127 Pfam PF00072 Response regulator receiver domain 9 121 1.9E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_04960 5976b11431ce5aaefa5113fc98363d7c 385 SUPERFAMILY SSF53756 8 375 8.07E-29 T 14-10-2018 HL41_04960 5976b11431ce5aaefa5113fc98363d7c 385 Pfam PF02684 Lipid-A-disaccharide synthetase 9 349 1.6E-92 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 HL41_04960 5976b11431ce5aaefa5113fc98363d7c 385 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 1 371 6.9E-80 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 HL41_06060 0a71a264181f4b76f037c07cd337d8d8 589 Pfam PF07715 TonB-dependent Receptor Plug Domain 75 148 3.8E-9 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain HL41_06060 0a71a264181f4b76f037c07cd337d8d8 589 Gene3D G3DSA:2.170.130.10 68 157 3.4E-13 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily HL41_06060 0a71a264181f4b76f037c07cd337d8d8 589 Pfam PF00593 TonB dependent receptor 166 587 6.2E-22 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel HL41_06060 0a71a264181f4b76f037c07cd337d8d8 589 Gene3D G3DSA:2.40.170.20 158 588 8.5E-39 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily HL41_06060 0a71a264181f4b76f037c07cd337d8d8 589 SUPERFAMILY SSF56935 35 587 1.5E-66 T 14-10-2018 HL41_03555 f56598128aa496fbcb45f6933f64eb09 147 SUPERFAMILY SSF49764 15 145 1.1E-42 T 14-10-2018 IPR008978 HSP20-like chaperone HL41_03555 f56598128aa496fbcb45f6933f64eb09 147 Pfam PF00011 Hsp20/alpha crystallin family 44 145 7.8E-26 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain HL41_03555 f56598128aa496fbcb45f6933f64eb09 147 Gene3D G3DSA:2.60.40.790 4 146 4.5E-42 T 14-10-2018 IPR008978 HSP20-like chaperone HL41_06220 7d1c3e5c0b9678e1753d4670b692a33b 206 SUPERFAMILY SSF53167 17 189 7.33E-28 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 HL41_06220 7d1c3e5c0b9678e1753d4670b692a33b 206 Pfam PF01048 Phosphorylase superfamily 22 199 6.3E-21 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HL41_06220 7d1c3e5c0b9678e1753d4670b692a33b 206 Gene3D G3DSA:3.40.50.1580 10 206 5.7E-27 T 14-10-2018 HL41_02740 957444004ebe28cfe8cef6987e938ae9 209 Gene3D G3DSA:2.170.120.30 28 129 1.4E-16 T 14-10-2018 HL41_02740 957444004ebe28cfe8cef6987e938ae9 209 Pfam PF07949 YbbR-like protein 37 116 1.5E-5 T 14-10-2018 IPR012505 YbbR-like HL41_02740 957444004ebe28cfe8cef6987e938ae9 209 Pfam PF07949 YbbR-like protein 142 203 5.4E-5 T 14-10-2018 IPR012505 YbbR-like HL41_02000 3738815ab8f7445a34d15971952f366c 177 SUPERFAMILY SSF53271 3 176 3.15E-48 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like HL41_02000 3738815ab8f7445a34d15971952f366c 177 Pfam PF00156 Phosphoribosyl transferase domain 13 160 6.2E-26 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HL41_02000 3738815ab8f7445a34d15971952f366c 177 Gene3D G3DSA:3.40.50.2020 1 177 4.1E-61 T 14-10-2018 HL41_02000 3738815ab8f7445a34d15971952f366c 177 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 173 1.5E-59 T 14-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 HL41_07630 45ca4d6fae89c953f3a7b2b00dc65645 413 SUPERFAMILY SSF51717 144 364 4.19E-17 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_07630 45ca4d6fae89c953f3a7b2b00dc65645 413 Gene3D G3DSA:3.20.20.20 110 406 3.3E-123 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HL41_07630 45ca4d6fae89c953f3a7b2b00dc65645 413 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 111 340 1.5E-45 T 14-10-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel HL41_06085 4d88b9292f66516e625363877a86afa4 546 Gene3D G3DSA:3.30.750.140 405 512 2.2E-7 T 14-10-2018 IPR038610 FliK-like, C-terminal domain superfamily HL41_06085 4d88b9292f66516e625363877a86afa4 546 Pfam PF02120 Flagellar hook-length control protein FliK 426 496 3.0E-11 T 14-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal HL41_07725 9c1050750941548fd0bbdb4fd56865b7 457 TIGRFAM TIGR01878 cas_Csa5: CRISPR type I-A/APERN-associated protein Csa5 330 446 1.6E-29 T 14-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 HL41_07335 e610d8aadca8486f1a04c7dc7cea00dd 389 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 233 1.0E-74 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HL41_07335 e610d8aadca8486f1a04c7dc7cea00dd 389 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 259 363 8.5E-29 T 14-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HL41_07335 e610d8aadca8486f1a04c7dc7cea00dd 389 Gene3D G3DSA:3.40.50.920 250 386 5.6E-45 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HL41_07335 e610d8aadca8486f1a04c7dc7cea00dd 389 SUPERFAMILY SSF52518 11 248 7.57E-71 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold HL41_07335 e610d8aadca8486f1a04c7dc7cea00dd 389 SUPERFAMILY SSF52922 250 375 3.8E-36 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 HL41_07335 e610d8aadca8486f1a04c7dc7cea00dd 389 Gene3D G3DSA:3.40.50.970 3 248 6.9E-97 T 14-10-2018 HL41_04095 9206e17dfcedfcfec175973d8de35a14 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 94 3.6E-27 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HL41_04095 9206e17dfcedfcfec175973d8de35a14 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 23.164 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HL41_04095 9206e17dfcedfcfec175973d8de35a14 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 4.6E-20 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HL41_04095 9206e17dfcedfcfec175973d8de35a14 98 Gene3D G3DSA:1.10.20.60 1 93 1.9E-28 T 14-10-2018 HL41_04095 9206e17dfcedfcfec175973d8de35a14 98 SUPERFAMILY SSF141000 3 93 7.32E-29 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 HL41_07120 56e8a2f4eedea9b25fb23426d89e1489 805 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 67 430 6.8E-36 T 14-10-2018 IPR010090 Phage tail tape measure protein HL41_07120 56e8a2f4eedea9b25fb23426d89e1489 805 Pfam PF10145 Phage-related minor tail protein 109 301 1.0E-16 T 14-10-2018 IPR010090 Phage tail tape measure protein HL41_04340 33d4bc681dd6a933c864ea5ef9438281 252 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 59 200 1.5E-23 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HL41_04340 33d4bc681dd6a933c864ea5ef9438281 252 Gene3D G3DSA:3.40.50.970 62 250 1.5E-21 T 14-10-2018 HL41_04340 33d4bc681dd6a933c864ea5ef9438281 252 SUPERFAMILY SSF52518 15 242 3.5E-54 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold HL41_08150 9d96762892d144f7040f494df2d2060c 119 Pfam PF02391 MoaE protein 22 117 3.1E-15 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 HL41_08150 9d96762892d144f7040f494df2d2060c 119 Gene3D G3DSA:3.90.1170.40 4 119 2.5E-17 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 HL41_08150 9d96762892d144f7040f494df2d2060c 119 SUPERFAMILY SSF54690 22 117 1.96E-17 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 HL41_00830 5e7746e97807172a61e6b89ab0db5220 255 PIRSF PIRSF017269 1 255 5.3E-79 T 14-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 HL41_00830 5e7746e97807172a61e6b89ab0db5220 255 Gene3D G3DSA:3.10.330.20 3 62 1.6E-20 T 14-10-2018 HL41_00830 5e7746e97807172a61e6b89ab0db5220 255 SUPERFAMILY SSF53335 2 251 3.04E-66 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_00830 5e7746e97807172a61e6b89ab0db5220 255 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 58 233 1.9E-29 T 14-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 HL41_00830 5e7746e97807172a61e6b89ab0db5220 255 Gene3D G3DSA:3.40.50.150 64 255 3.3E-66 T 14-10-2018 HL41_07600 4bc13368ae47f918acc9cb80654cba7c 197 SUPERFAMILY SSF53323 7 194 4.71E-34 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HL41_07600 4bc13368ae47f918acc9cb80654cba7c 197 Gene3D G3DSA:3.40.920.10 2 196 3.9E-42 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HL41_07600 4bc13368ae47f918acc9cb80654cba7c 197 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 190 3.5E-33 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HL41_08555 7586ddd7c7a2cd938d2faccb031db180 434 PIRSF PIRSF006444 1 433 2.5E-209 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 HL41_08555 7586ddd7c7a2cd938d2faccb031db180 434 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 431 1.4E-32 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal HL41_08555 7586ddd7c7a2cd938d2faccb031db180 434 Pfam PF00501 AMP-binding enzyme 82 286 6.5E-19 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 HL41_08555 7586ddd7c7a2cd938d2faccb031db180 434 SUPERFAMILY SSF56801 30 396 1.3E-63 T 14-10-2018 HL41_08555 7586ddd7c7a2cd938d2faccb031db180 434 Gene3D G3DSA:3.40.50.12780 2 326 1.3E-135 T 14-10-2018 HL41_08555 7586ddd7c7a2cd938d2faccb031db180 434 Gene3D G3DSA:3.30.300.30 327 433 4.1E-35 T 14-10-2018 HL41_06195 6a10224bee583043e8520c5acd2bd6e6 1000 SUPERFAMILY SSF75712 442 538 5.1E-6 T 14-10-2018 HL41_06195 6a10224bee583043e8520c5acd2bd6e6 1000 Pfam PF13558 Putative exonuclease SbcCD, C subunit 893 955 1.3E-10 T 14-10-2018 HL41_06195 6a10224bee583043e8520c5acd2bd6e6 1000 Pfam PF13476 AAA domain 6 231 4.3E-20 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain HL41_06195 6a10224bee583043e8520c5acd2bd6e6 1000 SUPERFAMILY SSF52540 28 985 2.78E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_06195 6a10224bee583043e8520c5acd2bd6e6 1000 Gene3D G3DSA:3.40.50.300 754 998 5.3E-28 T 14-10-2018 HL41_06195 6a10224bee583043e8520c5acd2bd6e6 1000 Gene3D G3DSA:3.40.50.300 1 292 7.3E-37 T 14-10-2018 HL41_03705 05575cfe0362ece1dea36cf631a21085 213 Gene3D G3DSA:1.20.950.20 1 201 4.6E-26 T 14-10-2018 HL41_03705 05575cfe0362ece1dea36cf631a21085 213 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 127 146 6.0E-9 T 14-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 HL41_03705 05575cfe0362ece1dea36cf631a21085 213 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 9 32 6.0E-9 T 14-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 HL41_03705 05575cfe0362ece1dea36cf631a21085 213 SUPERFAMILY SSF81342 1 209 2.59E-34 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 HL41_03705 05575cfe0362ece1dea36cf631a21085 213 Pfam PF01292 Prokaryotic cytochrome b561 7 202 1.8E-29 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 HL41_04710 27dfd45a7a5ba41fe195d998f0ebd6de 263 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 252 2.2E-74 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 HL41_04710 27dfd45a7a5ba41fe195d998f0ebd6de 263 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 253 1.4E-66 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 HL41_04710 27dfd45a7a5ba41fe195d998f0ebd6de 263 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 HL41_04710 27dfd45a7a5ba41fe195d998f0ebd6de 263 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 258 18.953 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 Gene3D G3DSA:3.90.10.10 37 149 1.0E-21 T 14-10-2018 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 Pfam PF02085 Class III cytochrome C family 293 394 1.9E-10 T 14-10-2018 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 Pfam PF02085 Class III cytochrome C family 163 262 9.7E-8 T 14-10-2018 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 Pfam PF02085 Class III cytochrome C family 60 143 1.3E-7 T 14-10-2018 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 Gene3D G3DSA:3.90.10.10 152 270 5.2E-24 T 14-10-2018 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 PRINTS PR00609 Class III cytochrome C signature 352 363 7.5E-5 T 14-10-2018 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 PRINTS PR00609 Class III cytochrome C signature 298 307 7.5E-5 T 14-10-2018 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 PRINTS PR00609 Class III cytochrome C signature 477 484 7.5E-5 T 14-10-2018 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 PRINTS PR00609 Class III cytochrome C signature 311 318 7.5E-5 T 14-10-2018 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 Gene3D G3DSA:3.90.10.10 379 529 8.9E-36 T 14-10-2018 HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 SUPERFAMILY SSF48695 45 527 7.81E-69 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_08630 4ed9f11ee765caac7ab63d32e05b32cc 536 Gene3D G3DSA:3.90.10.10 282 366 3.9E-17 T 14-10-2018 HL41_04365 a3b4a7555dc29cc6ee9b89bea1dd94b8 402 Gene3D G3DSA:3.40.50.2000 3 383 2.1E-136 T 14-10-2018 HL41_04365 a3b4a7555dc29cc6ee9b89bea1dd94b8 402 Gene3D G3DSA:3.40.50.2000 188 382 2.1E-136 T 14-10-2018 HL41_04365 a3b4a7555dc29cc6ee9b89bea1dd94b8 402 Pfam PF00534 Glycosyl transferases group 1 209 376 4.8E-28 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 HL41_04365 a3b4a7555dc29cc6ee9b89bea1dd94b8 402 SUPERFAMILY SSF53756 29 397 3.84E-51 T 14-10-2018 HL41_01470 a08c4209f40def5e6da8a70eb39b2181 160 Gene3D G3DSA:3.30.1330.200 1 160 1.8E-15 T 14-10-2018 IPR038592 CheD-like superfamily HL41_01470 a08c4209f40def5e6da8a70eb39b2181 160 SUPERFAMILY SSF64438 2 152 1.19E-12 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic HL41_03800 4ee59cb030e33c99ceaa7fbda80a9986 71 Pfam PF11146 Protein of unknown function (DUF2905) 5 68 1.7E-24 T 14-10-2018 IPR021320 Protein of unknown function DUF2905 HL41_05670 9f272195010d0b4936820729695209d6 243 Pfam PF00902 Sec-independent protein translocase protein (TatC) 13 224 2.3E-59 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_05670 9f272195010d0b4936820729695209d6 243 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 6 240 14.326 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_05670 9f272195010d0b4936820729695209d6 243 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 87 105 2.9E-28 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_05670 9f272195010d0b4936820729695209d6 243 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 105 131 2.9E-28 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_05670 9f272195010d0b4936820729695209d6 243 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 10 37 2.9E-28 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_05670 9f272195010d0b4936820729695209d6 243 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 156 184 2.9E-28 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_05670 9f272195010d0b4936820729695209d6 243 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 11 229 6.2E-52 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HL41_02875 864d4caeacc316f3515110c05f879613 384 Pfam PF01458 Uncharacterized protein family (UPF0051) 134 357 4.7E-54 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 HL41_02875 864d4caeacc316f3515110c05f879613 384 SUPERFAMILY SSF101960 49 378 6.41E-76 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily HL41_04180 43120c7519bb174c2a8ab5cd2a6e3bca 309 Pfam PF04055 Radical SAM superfamily 80 214 4.0E-9 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_04180 43120c7519bb174c2a8ab5cd2a6e3bca 309 SUPERFAMILY SSF102114 82 292 1.22E-11 T 14-10-2018 HL41_04180 43120c7519bb174c2a8ab5cd2a6e3bca 309 Gene3D G3DSA:3.20.20.70 72 299 5.1E-14 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_04180 43120c7519bb174c2a8ab5cd2a6e3bca 309 PIRSF PIRSF004869 4 305 1.6E-86 T 14-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted HL41_07065 6a3c3699e531e60228ed7e6364bdad9c 299 TIGRFAM TIGR04387 capsid_maj_N4: major capsid protein, N4-gp56 family 7 297 1.5E-42 T 14-10-2018 HL41_06795 6a8b63031e662a3711972bc5acfdb1df 279 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 11 276 1.8E-100 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 HL41_06795 6a8b63031e662a3711972bc5acfdb1df 279 Pfam PF05681 Fumarate hydratase (Fumerase) 12 276 1.4E-107 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 HL41_00595 51a99686b203e04a4db8ac152e0a2fe7 173 ProSitePatterns PS01265 Tpx family signature. 87 98 - T 14-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 HL41_00595 51a99686b203e04a4db8ac152e0a2fe7 173 Gene3D G3DSA:3.40.30.10 3 169 1.6E-47 T 14-10-2018 HL41_00595 51a99686b203e04a4db8ac152e0a2fe7 173 Pfam PF08534 Redoxin 23 163 5.3E-22 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 HL41_00595 51a99686b203e04a4db8ac152e0a2fe7 173 SUPERFAMILY SSF52833 7 164 9.45E-44 T 14-10-2018 IPR036249 Thioredoxin-like superfamily HL41_00595 51a99686b203e04a4db8ac152e0a2fe7 173 Hamap MF_00269 Thiol peroxidase [tpx]. 6 167 35.193 T 14-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 HL41_08040 26261c4e89bea60cf1b258995536d49d 284 SUPERFAMILY SSF102114 18 190 2.35E-7 T 14-10-2018 HL41_08040 26261c4e89bea60cf1b258995536d49d 284 Pfam PF04055 Radical SAM superfamily 24 184 5.5E-8 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_08040 26261c4e89bea60cf1b258995536d49d 284 Gene3D G3DSA:3.80.30.30 52 263 4.9E-12 T 14-10-2018 HL41_08560 8da445d286be2f10461094bfda52950d 139 Gene3D G3DSA:3.30.2130.10 2 138 3.3E-43 T 14-10-2018 HL41_08560 8da445d286be2f10461094bfda52950d 139 SUPERFAMILY SSF55021 4 68 1.86E-15 T 14-10-2018 HL41_08560 8da445d286be2f10461094bfda52950d 139 SUPERFAMILY SSF55021 73 137 7.25E-13 T 14-10-2018 HL41_08560 8da445d286be2f10461094bfda52950d 139 Pfam PF01842 ACT domain 73 130 1.5E-7 T 14-10-2018 IPR002912 ACT domain HL41_08560 8da445d286be2f10461094bfda52950d 139 Pfam PF01842 ACT domain 6 55 2.5E-7 T 14-10-2018 IPR002912 ACT domain HL41_04520 3567da9b65e4f9fe872bc78b10e57931 174 SUPERFAMILY SSF55469 4 173 9.82E-64 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HL41_04520 3567da9b65e4f9fe872bc78b10e57931 174 Pfam PF00881 Nitroreductase family 65 154 9.9E-20 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HL41_04520 3567da9b65e4f9fe872bc78b10e57931 174 Pfam PF00881 Nitroreductase family 10 64 7.4E-21 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HL41_04520 3567da9b65e4f9fe872bc78b10e57931 174 Gene3D G3DSA:3.40.109.10 3 174 1.9E-67 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HL41_05010 f0376776a7950b59d4d50fff5968a106 73 Pfam PF01106 NifU-like domain 5 71 2.7E-30 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 HL41_05010 f0376776a7950b59d4d50fff5968a106 73 SUPERFAMILY SSF117916 3 73 1.8E-25 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily HL41_05010 f0376776a7950b59d4d50fff5968a106 73 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 11 73 8.0E-23 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 HL41_05010 f0376776a7950b59d4d50fff5968a106 73 Gene3D G3DSA:3.30.300.130 1 73 3.9E-31 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily HL41_09175 b1098ccd35a1a2e3e547fb1be1b524bf 359 SUPERFAMILY SSF56601 3 354 1.07E-42 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like HL41_09175 b1098ccd35a1a2e3e547fb1be1b524bf 359 Gene3D G3DSA:3.40.710.10 2 352 7.8E-45 T 14-10-2018 HL41_09175 b1098ccd35a1a2e3e547fb1be1b524bf 359 Pfam PF00144 Beta-lactamase 11 341 1.0E-31 T 14-10-2018 IPR001466 Beta-lactamase-related HL41_09170 0fb6cb9932e4ba154dd364c9d9ce083e 90 Pfam PF06305 Lipopolysaccharide assembly protein A domain 27 82 2.3E-13 T 14-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 HL41_04990 128a048c3252d1a0fdde249816297b7f 338 Pfam PF02470 MlaD protein 38 115 3.5E-17 T 14-10-2018 IPR003399 Mce/MlaD HL41_02335 7f1357b79b2a54bf9316b8a22e031234 572 SUPERFAMILY SSF53697 53 402 6.02E-67 T 14-10-2018 HL41_02335 7f1357b79b2a54bf9316b8a22e031234 572 Gene3D G3DSA:3.40.50.10490 52 224 1.8E-39 T 14-10-2018 HL41_02335 7f1357b79b2a54bf9316b8a22e031234 572 Gene3D G3DSA:3.40.50.10490 225 306 2.4E-6 T 14-10-2018 HL41_02335 7f1357b79b2a54bf9316b8a22e031234 572 Pfam PF00342 Phosphoglucose isomerase 82 297 1.8E-16 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_02335 7f1357b79b2a54bf9316b8a22e031234 572 PRINTS PR00662 Glucose-6-phosphate isomerase signature 87 106 8.2E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_02335 7f1357b79b2a54bf9316b8a22e031234 572 PRINTS PR00662 Glucose-6-phosphate isomerase signature 271 292 8.2E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_02335 7f1357b79b2a54bf9316b8a22e031234 572 PRINTS PR00662 Glucose-6-phosphate isomerase signature 196 214 8.2E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HL41_04305 b26857dbe9bab220f03b819d51362a47 241 Pfam PF03692 Putative zinc- or iron-chelating domain 21 122 3.5E-11 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein HL41_08315 62e269aecbcb383a038e3262a3390f98 382 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 12 380 2.0E-82 T 14-10-2018 HL41_08315 62e269aecbcb383a038e3262a3390f98 382 Pfam PF01960 ArgJ family 10 382 1.6E-139 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HL41_08315 62e269aecbcb383a038e3262a3390f98 382 Gene3D G3DSA:3.60.70.12 1 255 1.4E-96 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HL41_08315 62e269aecbcb383a038e3262a3390f98 382 SUPERFAMILY SSF56266 4 378 3.27E-132 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HL41_08315 62e269aecbcb383a038e3262a3390f98 382 Gene3D G3DSA:3.10.20.340 256 382 1.5E-42 T 14-10-2018 HL41_08315 62e269aecbcb383a038e3262a3390f98 382 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 382 123.171 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HL41_08315 62e269aecbcb383a038e3262a3390f98 382 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 3 382 2.1E-125 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HL41_07320 5064c7d98e276f10a965992db3495e9b 355 SUPERFAMILY SSF52540 1 216 3.19E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_07320 5064c7d98e276f10a965992db3495e9b 355 SUPERFAMILY SSF75138 209 322 9.55E-28 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HL41_07320 5064c7d98e276f10a965992db3495e9b 355 Gene3D G3DSA:3.40.1390.20 202 340 1.2E-42 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily HL41_07320 5064c7d98e276f10a965992db3495e9b 355 Pfam PF13500 AAA domain 2 209 8.6E-13 T 14-10-2018 HL41_07320 5064c7d98e276f10a965992db3495e9b 355 Pfam PF07085 DRTGG domain 214 318 7.6E-27 T 14-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HL41_01675 bf1634bf602f479dd5643095354e8a4b 551 Gene3D G3DSA:1.10.287.950 211 368 1.2E-10 T 14-10-2018 HL41_01675 bf1634bf602f479dd5643095354e8a4b 551 SUPERFAMILY SSF58104 244 424 3.14E-6 T 14-10-2018 HL41_03530 6d09b5a012c30e8e0b042fff673d6c80 259 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 4.8E-111 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 HL41_03530 6d09b5a012c30e8e0b042fff673d6c80 259 Gene3D G3DSA:3.20.20.70 1 259 2.7E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_03530 6d09b5a012c30e8e0b042fff673d6c80 259 SUPERFAMILY SSF51366 1 256 1.96E-77 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 HL41_03530 6d09b5a012c30e8e0b042fff673d6c80 259 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 45.615 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 HL41_03530 6d09b5a012c30e8e0b042fff673d6c80 259 Pfam PF00977 Histidine biosynthesis protein 5 240 6.3E-82 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 HL41_01950 482bbcb1582e6add9eba2cb31cfddd8e 274 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 267 34.382 T 14-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 HL41_01950 482bbcb1582e6add9eba2cb31cfddd8e 274 Gene3D G3DSA:3.40.50.720 101 232 3.7E-91 T 14-10-2018 HL41_01950 482bbcb1582e6add9eba2cb31cfddd8e 274 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 4.6E-30 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 HL41_01950 482bbcb1582e6add9eba2cb31cfddd8e 274 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 116 186 9.2E-13 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase HL41_01950 482bbcb1582e6add9eba2cb31cfddd8e 274 Gene3D G3DSA:3.40.50.10860 5 249 3.7E-91 T 14-10-2018 HL41_01950 482bbcb1582e6add9eba2cb31cfddd8e 274 SUPERFAMILY SSF53223 2 101 1.04E-32 T 14-10-2018 HL41_01950 482bbcb1582e6add9eba2cb31cfddd8e 274 SUPERFAMILY SSF51735 102 256 1.5E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_01950 482bbcb1582e6add9eba2cb31cfddd8e 274 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 256 1.3E-78 T 14-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 HL41_03360 ed6c098f4f6b0ba8ffc4e7404c8cdf8d 381 Gene3D G3DSA:1.20.1530.20 3 375 5.1E-52 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily HL41_03360 ed6c098f4f6b0ba8ffc4e7404c8cdf8d 381 Pfam PF00999 Sodium/hydrogen exchanger family 9 361 2.5E-37 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HL41_04580 5fea21a34394629dd7da3ec1dd13988b 309 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 305 3.6E-45 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 HL41_04580 5fea21a34394629dd7da3ec1dd13988b 309 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 34 307 1.2E-66 T 14-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 HL41_04580 5fea21a34394629dd7da3ec1dd13988b 309 SUPERFAMILY SSF53335 12 307 7.15E-52 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_04580 5fea21a34394629dd7da3ec1dd13988b 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 229 245 5.1E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HL41_04580 5fea21a34394629dd7da3ec1dd13988b 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 290 307 5.1E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HL41_04580 5fea21a34394629dd7da3ec1dd13988b 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 5.1E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HL41_04580 5fea21a34394629dd7da3ec1dd13988b 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 113 123 5.1E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase HL41_04580 5fea21a34394629dd7da3ec1dd13988b 309 Gene3D G3DSA:3.30.70.3130 1 97 1.1E-8 T 14-10-2018 HL41_04580 5fea21a34394629dd7da3ec1dd13988b 309 Gene3D G3DSA:3.40.50.150 101 308 9.1E-62 T 14-10-2018 HL41_08305 ebcda138ae26071ac510bc996189762b 140 Gene3D G3DSA:3.40.50.2300 4 137 1.5E-8 T 14-10-2018 HL41_08305 ebcda138ae26071ac510bc996189762b 140 Pfam PF00072 Response regulator receiver domain 14 114 4.4E-5 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HL41_08305 ebcda138ae26071ac510bc996189762b 140 SUPERFAMILY SSF52172 4 135 1.71E-9 T 14-10-2018 IPR011006 CheY-like superfamily HL41_01070 0d71b676a8754ec5752db05efd35ad1c 141 Pfam PF00430 ATP synthase B/B' CF(0) 7 137 4.3E-16 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HL41_01070 0d71b676a8754ec5752db05efd35ad1c 141 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 139 10.031 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HL41_08070 6cc7e842dac3853c6839407b0c1781e5 117 SUPERFAMILY SSF64076 1 117 4.58E-20 T 14-10-2018 IPR036748 MTH938-like superfamily HL41_08070 6cc7e842dac3853c6839407b0c1781e5 117 Gene3D G3DSA:3.40.1230.10 1 117 5.5E-29 T 14-10-2018 IPR036748 MTH938-like superfamily HL41_08070 6cc7e842dac3853c6839407b0c1781e5 117 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 2 114 1.6E-19 T 14-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein HL41_07410 978e3a7f596fe3327790c62ca91f972d 408 Gene3D G3DSA:3.20.20.140 69 365 2.8E-68 T 14-10-2018 HL41_07410 978e3a7f596fe3327790c62ca91f972d 408 Gene3D G3DSA:2.30.40.10 29 403 2.8E-68 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HL41_07410 978e3a7f596fe3327790c62ca91f972d 408 SUPERFAMILY SSF51556 67 362 3.48E-59 T 14-10-2018 IPR032466 Metal-dependent hydrolase HL41_07410 978e3a7f596fe3327790c62ca91f972d 408 Pfam PF01979 Amidohydrolase family 64 402 7.7E-39 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 HL41_07410 978e3a7f596fe3327790c62ca91f972d 408 SUPERFAMILY SSF51338 7 80 7.78E-12 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 HL41_07305 0fc3dd454f6514d58fa1d387837f0377 587 Pfam PF02652 L-lactate permease 15 527 2.2E-182 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HL41_07305 0fc3dd454f6514d58fa1d387837f0377 587 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 14 529 1.9E-179 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HL41_00145 bca7b99ae88aee15249299a9b439a2f3 244 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HL41_00145 bca7b99ae88aee15249299a9b439a2f3 244 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 48 77 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 HL41_00145 bca7b99ae88aee15249299a9b439a2f3 244 SUPERFAMILY SSF53335 14 198 2.54E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HL41_00145 bca7b99ae88aee15249299a9b439a2f3 244 Pfam PF05175 Methyltransferase small domain 34 126 7.6E-10 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 HL41_00145 bca7b99ae88aee15249299a9b439a2f3 244 Gene3D G3DSA:3.40.50.150 9 243 1.6E-57 T 14-10-2018 HL41_09120 d8ebdb7d5b279094ce7cfcc2277ff6b6 115 Pfam PF11839 Alanine-zipper, major outer membrane lipoprotein 52 115 6.9E-9 T 14-10-2018 IPR021793 Major outer membrane lipoprotein Oprl HL41_07750 9b17a4f2b59d4710db5e151a631e53b1 164 Pfam PF01930 Domain of unknown function DUF83 5 164 2.0E-55 T 14-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 HL41_07750 9b17a4f2b59d4710db5e151a631e53b1 164 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 6 163 8.0E-29 T 14-10-2018 IPR013343 CRISPR-associated protein Cas4 HL41_07750 9b17a4f2b59d4710db5e151a631e53b1 164 Gene3D G3DSA:3.90.320.10 1 164 3.2E-7 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal HL41_08290 fe7533bdf6369f955b4334d231d9c821 263 SUPERFAMILY SSF52402 1 135 1.53E-22 T 14-10-2018 HL41_08290 fe7533bdf6369f955b4334d231d9c821 263 Gene3D G3DSA:3.40.50.620 136 263 1.7E-31 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_08290 fe7533bdf6369f955b4334d231d9c821 263 SUPERFAMILY SSF52402 142 263 3.63E-29 T 14-10-2018 HL41_08290 fe7533bdf6369f955b4334d231d9c821 263 PRINTS PR01438 Universal stress protein signature 1 19 8.9E-19 T 14-10-2018 IPR006015 Universal stress protein A HL41_08290 fe7533bdf6369f955b4334d231d9c821 263 PRINTS PR01438 Universal stress protein signature 223 235 8.9E-19 T 14-10-2018 IPR006015 Universal stress protein A HL41_08290 fe7533bdf6369f955b4334d231d9c821 263 PRINTS PR01438 Universal stress protein signature 241 263 8.9E-19 T 14-10-2018 IPR006015 Universal stress protein A HL41_08290 fe7533bdf6369f955b4334d231d9c821 263 Pfam PF00582 Universal stress protein family 2 133 2.1E-15 T 14-10-2018 IPR006016 UspA HL41_08290 fe7533bdf6369f955b4334d231d9c821 263 Pfam PF00582 Universal stress protein family 141 263 4.0E-24 T 14-10-2018 IPR006016 UspA HL41_08290 fe7533bdf6369f955b4334d231d9c821 263 Gene3D G3DSA:3.40.50.620 1 134 2.1E-20 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_04285 dfafad8d3e5d8aebf27c1e8cfecf6cd3 132 Pfam PF05433 Glycine zipper 2TM domain 30 70 2.4E-10 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 HL41_03025 8bd7c902bc5e3b31c044c61ab44a4d64 412 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 13 396 7.9E-166 T 14-10-2018 IPR023874 DNA modification/repair radical SAM protein, putative HL41_03025 8bd7c902bc5e3b31c044c61ab44a4d64 412 Pfam PF12836 Helix-hairpin-helix motif 325 356 1.2E-6 T 14-10-2018 HL41_03025 8bd7c902bc5e3b31c044c61ab44a4d64 412 SUPERFAMILY SSF47781 304 382 1.2E-13 T 14-10-2018 IPR010994 RuvA domain 2-like HL41_03025 8bd7c902bc5e3b31c044c61ab44a4d64 412 SMART SM00278 334 353 0.0011 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HL41_03025 8bd7c902bc5e3b31c044c61ab44a4d64 412 Gene3D G3DSA:3.20.20.70 56 204 1.5E-8 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_03025 8bd7c902bc5e3b31c044c61ab44a4d64 412 Gene3D G3DSA:1.10.150.320 317 376 1.2E-6 T 14-10-2018 HL41_03025 8bd7c902bc5e3b31c044c61ab44a4d64 412 SUPERFAMILY SSF102114 50 201 1.24E-13 T 14-10-2018 HL41_05060 274b19a0cd8a4f2f1f889811c0e60b57 199 SUPERFAMILY SSF54631 1 122 2.68E-35 T 14-10-2018 HL41_05060 274b19a0cd8a4f2f1f889811c0e60b57 199 SMART SM00116 10 59 6.9E-11 T 14-10-2018 IPR000644 CBS domain HL41_05060 274b19a0cd8a4f2f1f889811c0e60b57 199 SMART SM00116 74 121 4.6E-13 T 14-10-2018 IPR000644 CBS domain HL41_05060 274b19a0cd8a4f2f1f889811c0e60b57 199 Gene3D G3DSA:3.10.580.10 1 145 1.1E-37 T 14-10-2018 HL41_05060 274b19a0cd8a4f2f1f889811c0e60b57 199 Pfam PF00571 CBS domain 68 118 3.6E-14 T 14-10-2018 IPR000644 CBS domain HL41_05060 274b19a0cd8a4f2f1f889811c0e60b57 199 Pfam PF00571 CBS domain 3 58 2.0E-13 T 14-10-2018 IPR000644 CBS domain HL41_04705 6bc1dbac7203cead536a8bac88ba490a 272 SUPERFAMILY SSF51735 5 143 7.23E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_04705 6bc1dbac7203cead536a8bac88ba490a 272 Pfam PF02153 Prephenate dehydrogenase 37 250 3.3E-31 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 HL41_04705 6bc1dbac7203cead536a8bac88ba490a 272 Gene3D G3DSA:1.10.3660.10 156 271 2.3E-17 T 14-10-2018 HL41_04705 6bc1dbac7203cead536a8bac88ba490a 272 SUPERFAMILY SSF48179 149 250 1.62E-21 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 HL41_04705 6bc1dbac7203cead536a8bac88ba490a 272 Gene3D G3DSA:3.40.50.720 1 154 5.8E-35 T 14-10-2018 HL41_05155 48720a6de7d60e7f6b48a7b34bbb16c8 263 SUPERFAMILY SSF52540 1 258 4.19E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HL41_05155 48720a6de7d60e7f6b48a7b34bbb16c8 263 Pfam PF13614 AAA domain 1 179 7.1E-56 T 14-10-2018 IPR025669 AAA domain HL41_05155 48720a6de7d60e7f6b48a7b34bbb16c8 263 Gene3D G3DSA:3.40.50.300 1 261 5.2E-73 T 14-10-2018 HL41_06230 d717f46d288528385eaf2c5177bb4cb9 229 Pfam PF01618 MotA/TolQ/ExbB proton channel family 111 213 6.9E-36 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel HL41_01065 6448d05ec377c47691063288ec238912 363 Pfam PF01098 Cell cycle protein 18 358 2.7E-67 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HL41_00090 9ed724bdb707e8683fb0524d330f816e 89 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 20 70 4.1E-12 T 14-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter HL41_03365 951ca29c6ec1a5c56fd454e22f62bc0a 269 SUPERFAMILY SSF48239 6 261 6.4E-20 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid HL41_03365 951ca29c6ec1a5c56fd454e22f62bc0a 269 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 229 260 1.6 T 14-10-2018 IPR001330 PFTB repeat GO:0003824 HL41_03365 951ca29c6ec1a5c56fd454e22f62bc0a 269 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 179 214 2.6 T 14-10-2018 IPR001330 PFTB repeat GO:0003824 HL41_03365 951ca29c6ec1a5c56fd454e22f62bc0a 269 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 12 50 5.7E-4 T 14-10-2018 IPR001330 PFTB repeat GO:0003824 HL41_03255 a3ff4a3ead3e5304cdfc7dce52b334ae 693 Gene3D G3DSA:3.40.1380.40 423 547 7.5E-18 T 14-10-2018 HL41_03255 a3ff4a3ead3e5304cdfc7dce52b334ae 693 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 38 474 2.0E-15 T 14-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 HL41_03675 e226b33630ac7f0df6ea7a3c3f1ba676 553 SUPERFAMILY SSF69318 242 418 3.14E-9 T 14-10-2018 HL41_00795 98197e7cd4272b1d2c75f8be24a107b7 361 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 63 234 3.1E-8 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like HL41_06335 e5fbaec3c541287e1b7336be9086f397 432 Pfam PF03023 MviN-like protein 43 429 3.0E-22 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HL41_00045 500cb5ae61bf25fe4ca20791ee13fe62 218 Pfam PF01865 Protein of unknown function DUF47 8 210 8.1E-27 T 14-10-2018 IPR018445 Putative phosphate transport regulator HL41_00045 500cb5ae61bf25fe4ca20791ee13fe62 218 Gene3D G3DSA:1.20.58.220 9 213 3.1E-23 T 14-10-2018 IPR038078 PhoU-like domain superfamily HL41_04460 e56abbe86365c226b6272fc15b7b2f48 328 Pfam PF03916 Polysulphide reductase, NrfD 19 323 9.5E-32 T 14-10-2018 IPR005614 NrfD family HL41_04460 e56abbe86365c226b6272fc15b7b2f48 328 Gene3D G3DSA:1.20.1630.10 13 265 1.2E-19 T 14-10-2018 HL41_04880 b06bb921ef1aee9a30e74a41be449496 122 Gene3D G3DSA:1.10.443.10 5 121 4.1E-27 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 HL41_04880 b06bb921ef1aee9a30e74a41be449496 122 Pfam PF00589 Phage integrase family 16 113 5.3E-27 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HL41_04880 b06bb921ef1aee9a30e74a41be449496 122 SUPERFAMILY SSF56349 18 113 2.94E-26 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HL41_02455 040822ffdd4dcdabe62be23499d7da0c 287 Gene3D G3DSA:3.40.50.620 144 285 2.0E-17 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HL41_02455 040822ffdd4dcdabe62be23499d7da0c 287 SUPERFAMILY SSF52402 4 139 1.17E-7 T 14-10-2018 HL41_02455 040822ffdd4dcdabe62be23499d7da0c 287 Pfam PF00582 Universal stress protein family 146 282 1.0E-13 T 14-10-2018 IPR006016 UspA HL41_02455 040822ffdd4dcdabe62be23499d7da0c 287 SUPERFAMILY SSF52402 150 283 7.7E-15 T 14-10-2018 HL41_04495 bb780001ea4fbdc48d4f06fd5c205c3f 246 PIRSF PIRSF006648 3 246 3.1E-29 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_04495 bb780001ea4fbdc48d4f06fd5c205c3f 246 Pfam PF01061 ABC-2 type transporter 21 211 4.0E-19 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 HL41_04495 bb780001ea4fbdc48d4f06fd5c205c3f 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 135 159 6.1E-13 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_04495 bb780001ea4fbdc48d4f06fd5c205c3f 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 25 46 6.1E-13 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_04495 bb780001ea4fbdc48d4f06fd5c205c3f 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 192 211 6.1E-13 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_04495 bb780001ea4fbdc48d4f06fd5c205c3f 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 6.1E-13 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_04495 bb780001ea4fbdc48d4f06fd5c205c3f 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 6.1E-13 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 HL41_02380 a45fd41bf97de15053e4473e97b963df 73 Gene3D G3DSA:3.10.20.30 1 73 2.7E-13 T 14-10-2018 IPR012675 Beta-grasp domain superfamily HL41_02380 a45fd41bf97de15053e4473e97b963df 73 SUPERFAMILY SSF54285 1 73 2.45E-14 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp HL41_02380 a45fd41bf97de15053e4473e97b963df 73 Pfam PF02597 ThiS family 4 73 1.6E-12 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 HL41_00715 01c4eb3711df98b2e74dc5ee526a2c03 123 Pfam PF09723 Zinc ribbon domain 1 39 1.3E-14 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_00715 01c4eb3711df98b2e74dc5ee526a2c03 123 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 45 3.7E-15 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_00715 01c4eb3711df98b2e74dc5ee526a2c03 123 SMART SM00834 1 41 3.8E-13 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HL41_04420 04eb8e8ae72af533db2127d070898fe1 205 Pfam PF04250 Protein of unknown function (DUF429) 13 125 3.8E-4 T 14-10-2018 IPR007362 Protein of unknown function DUF429 HL41_07000 f7450d02e54b2c057eed42aa9dc7cd59 98 Gene3D G3DSA:1.10.10.10 5 92 5.8E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_00995 ffed51d9524648cf56f2b03c30ba2bd7 1074 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 6.0E-8 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HL41_00995 ffed51d9524648cf56f2b03c30ba2bd7 1074 PRINTS PR01005 Flagellar hook-associated protein signature 219 237 6.0E-8 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HL41_00995 ffed51d9524648cf56f2b03c30ba2bd7 1074 PRINTS PR01005 Flagellar hook-associated protein signature 52 74 6.0E-8 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HL41_00995 ffed51d9524648cf56f2b03c30ba2bd7 1074 PRINTS PR01005 Flagellar hook-associated protein signature 161 185 6.0E-8 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HL41_00995 ffed51d9524648cf56f2b03c30ba2bd7 1074 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 1032 1071 5.0E-12 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HL41_00995 ffed51d9524648cf56f2b03c30ba2bd7 1074 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 290 6.7E-67 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HL41_00995 ffed51d9524648cf56f2b03c30ba2bd7 1074 SUPERFAMILY SSF64518 171 1071 4.05E-18 T 14-10-2018 HL41_01595 a9b102b22bf821595a15c27da71fa041 472 Pfam PF03961 Flagellar Assembly Protein A 19 467 1.5E-76 T 14-10-2018 IPR005646 Flagellar assembly protein A HL41_01430 84edf2c02756330ea896cc7a7f3407b7 287 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 50 72 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HL41_01430 84edf2c02756330ea896cc7a7f3407b7 287 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 7 176 4.6E-37 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 HL41_01430 84edf2c02756330ea896cc7a7f3407b7 287 Gene3D G3DSA:1.20.120.1760 1 177 4.7E-16 T 14-10-2018 HL41_01430 84edf2c02756330ea896cc7a7f3407b7 287 Pfam PF01066 CDP-alcohol phosphatidyltransferase 7 72 1.6E-15 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HL41_02780 cc668f9e8e12afb4fbb4a38e2611da2e 246 Pfam PF01694 Rhomboid family 68 225 2.3E-38 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HL41_02780 cc668f9e8e12afb4fbb4a38e2611da2e 246 SUPERFAMILY SSF144091 9 225 2.75E-44 T 14-10-2018 HL41_02780 cc668f9e8e12afb4fbb4a38e2611da2e 246 Gene3D G3DSA:1.20.1540.10 9 230 5.4E-32 T 14-10-2018 IPR035952 Rhomboid-like superfamily HL41_07005 2f7be579507b1bd06f030cd80514e208 163 Pfam PF11985 Protein of unknown function (DUF3486) 26 162 1.5E-17 T 14-10-2018 IPR021874 Bacteriophage Mu, Gp27 HL41_08380 5d23eafc7eb16f57751867629be6a230 223 SUPERFAMILY SSF81342 3 218 6.51E-33 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 HL41_08380 5d23eafc7eb16f57751867629be6a230 223 Gene3D G3DSA:1.20.950.20 1 223 5.4E-38 T 14-10-2018 HL41_08380 5d23eafc7eb16f57751867629be6a230 223 Pfam PF01292 Prokaryotic cytochrome b561 7 197 7.1E-20 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 HL41_07510 efef05a93dcfd348918d8219cf9786b0 581 Gene3D G3DSA:3.40.50.2000 1 317 9.0E-35 T 14-10-2018 HL41_07510 efef05a93dcfd348918d8219cf9786b0 581 SUPERFAMILY SSF53756 125 349 1.41E-6 T 14-10-2018 HL41_04190 b32cf30ad696adf7f5bccd431ad01871 199 SUPERFAMILY SSF109604 4 183 4.19E-34 T 14-10-2018 HL41_04190 b32cf30ad696adf7f5bccd431ad01871 199 Pfam PF13023 HD domain 18 146 7.1E-28 T 14-10-2018 IPR006674 HD domain HL41_04190 b32cf30ad696adf7f5bccd431ad01871 199 Gene3D G3DSA:1.10.3210.10 1 183 6.1E-45 T 14-10-2018 HL41_04190 b32cf30ad696adf7f5bccd431ad01871 199 SMART SM00471 32 145 6.1E-10 T 14-10-2018 IPR003607 HD/PDEase domain HL41_04490 152ba360cba2ed80329694a3c6840b63 136 SUPERFAMILY SSF103481 41 133 1.03E-13 T 14-10-2018 HL41_04490 152ba360cba2ed80329694a3c6840b63 136 Pfam PF00892 EamA-like transporter family 2 133 1.2E-23 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HL41_01315 752162ddaeb333e1b09777d8cacbdf62 316 Pfam PF04055 Radical SAM superfamily 33 192 4.9E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HL41_01315 752162ddaeb333e1b09777d8cacbdf62 316 SUPERFAMILY SSF102114 33 223 6.41E-24 T 14-10-2018 HL41_01315 752162ddaeb333e1b09777d8cacbdf62 316 Gene3D G3DSA:3.20.20.70 23 273 2.5E-23 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HL41_05000 974e9fdb3c9466f261edd0c58b4a1a43 255 Pfam PF02405 Permease MlaE 43 252 5.6E-77 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 HL41_05000 974e9fdb3c9466f261edd0c58b4a1a43 255 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 15 255 4.3E-74 T 14-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria HL41_05195 c027cdc07244d4a6c15d1f0f55270bf3 431 SUPERFAMILY SSF81665 77 402 1.44E-5 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 HL41_05195 c027cdc07244d4a6c15d1f0f55270bf3 431 PIRSF PIRSF005353 1 430 1.1E-159 T 14-10-2018 IPR026033 Purine permease PbuG-like HL41_05195 c027cdc07244d4a6c15d1f0f55270bf3 431 Pfam PF00860 Permease family 17 391 8.5E-40 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 HL41_06565 90273f2506803545b871257ab96cac72 104 Gene3D G3DSA:3.60.15.10 4 86 1.7E-8 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_06565 90273f2506803545b871257ab96cac72 104 SUPERFAMILY SSF56281 7 58 1.56E-6 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like HL41_02990 7f84aa0dcf3277cf6815d3d7d76a7c31 310 SUPERFAMILY SSF103481 185 287 2.22E-18 T 14-10-2018 HL41_02990 7f84aa0dcf3277cf6815d3d7d76a7c31 310 SUPERFAMILY SSF103481 37 140 4.84E-17 T 14-10-2018 HL41_02990 7f84aa0dcf3277cf6815d3d7d76a7c31 310 Pfam PF00892 EamA-like transporter family 10 138 2.9E-22 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HL41_02990 7f84aa0dcf3277cf6815d3d7d76a7c31 310 Pfam PF00892 EamA-like transporter family 150 283 5.4E-28 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HL41_03290 40b5d2c4d8feb0a010aa59b47ac2e2e8 68 TIGRFAM TIGR04354 amphi-Trp: amphi-Trp domain 6 67 5.1E-13 T 14-10-2018 IPR027598 Amphi-Trp domain HL41_08375 70af2def8f887e7ac677c7d4996894c7 324 Gene3D G3DSA:3.30.70.20 23 300 2.0E-37 T 14-10-2018 HL41_08375 70af2def8f887e7ac677c7d4996894c7 324 SUPERFAMILY SSF54862 30 256 5.86E-48 T 14-10-2018 HL41_08375 70af2def8f887e7ac677c7d4996894c7 324 Pfam PF13247 4Fe-4S dicluster domain 110 218 3.3E-17 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HL41_05775 e4e6e46b036e9e766f1b5bbb304fabef 313 Pfam PF08349 Protein of unknown function (DUF1722) 193 309 1.3E-39 T 14-10-2018 IPR013560 Domain of unknown function DUF1722 HL41_05775 e4e6e46b036e9e766f1b5bbb304fabef 313 Pfam PF04463 Protein of unknown function (DUF523) 11 150 7.6E-32 T 14-10-2018 IPR007553 Domain of unknown function DUF523 HL41_01140 c448ca1156a4e900ccdf1e47a5f1b8c2 170 Pfam PF07238 PilZ domain 82 157 2.8E-11 T 14-10-2018 IPR009875 PilZ domain GO:0035438 HL41_02645 12425620881b57638fbf4762dba17046 165 Pfam PF03748 Flagellar basal body-associated protein FliL 70 164 5.2E-24 T 14-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 HL41_02300 948350abb33d84b2e515636badeba28e 193 SUPERFAMILY SSF53697 7 191 1.62E-51 T 14-10-2018 HL41_02300 948350abb33d84b2e515636badeba28e 193 Gene3D G3DSA:3.40.50.10490 1 192 9.1E-71 T 14-10-2018 HL41_02300 948350abb33d84b2e515636badeba28e 193 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 3 190 35.311 T 14-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 HL41_02300 948350abb33d84b2e515636badeba28e 193 Pfam PF13580 SIS domain 14 147 4.0E-30 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HL41_03275 2cf72387ea7a92a009006346895e0833 264 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 176 247 3.4E-13 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 HL41_03275 2cf72387ea7a92a009006346895e0833 264 Gene3D G3DSA:3.40.50.2000 111 257 6.7E-18 T 14-10-2018 HL41_03275 2cf72387ea7a92a009006346895e0833 264 SUPERFAMILY SSF53756 2 245 2.41E-35 T 14-10-2018 HL41_08490 983b6af37887484d402eddeea7d22063 97 Pfam PF04341 Protein of unknown function, DUF485 6 91 2.4E-30 T 14-10-2018 IPR007436 Protein of unknown function DUF485 HL41_05315 22f001975085f7c3aa91e10a3ca4c9f0 126 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 7 123 1.1E-55 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HL41_05315 22f001975085f7c3aa91e10a3ca4c9f0 126 SUPERFAMILY SSF53137 12 126 4.25E-49 T 14-10-2018 HL41_05315 22f001975085f7c3aa91e10a3ca4c9f0 126 Gene3D G3DSA:3.30.420.80 1 126 3.2E-54 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 HL41_05315 22f001975085f7c3aa91e10a3ca4c9f0 126 Pfam PF00411 Ribosomal protein S11 16 125 5.0E-47 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HL41_05315 22f001975085f7c3aa91e10a3ca4c9f0 126 ProSitePatterns PS00054 Ribosomal protein S11 signature. 94 116 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site HL41_05315 22f001975085f7c3aa91e10a3ca4c9f0 126 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 126 33.149 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HL41_05315 22f001975085f7c3aa91e10a3ca4c9f0 126 PIRSF PIRSF002131 1 126 2.4E-53 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HL41_00335 f5b81747b1b3fd37698c80cab07fe1e0 404 SUPERFAMILY SSF103473 14 398 7.59E-51 T 14-10-2018 IPR036259 MFS transporter superfamily HL41_00335 f5b81747b1b3fd37698c80cab07fe1e0 404 Gene3D G3DSA:1.20.1250.20 12 399 3.0E-46 T 14-10-2018 HL41_00335 f5b81747b1b3fd37698c80cab07fe1e0 404 Pfam PF05977 Transmembrane secretion effector 10 398 5.3E-50 T 14-10-2018 IPR010290 Transmembrane secretion effector HL41_07550 052d2a8012b193d41c739fd4732218db 88 Pfam PF11154 Protein of unknown function (DUF2934) 6 39 1.7E-12 T 14-10-2018 IPR021327 Protein of unknown function DUF2934 HL41_07745 21e575953c2904cdf2bbfd10ee5446f6 97 Pfam PF13635 Domain of unknown function (DUF4143) 3 41 3.6E-10 T 14-10-2018 IPR025420 Domain of unknown function DUF4143 HL41_02220 e9575fa50c1fa169918cf5df0b660d2e 323 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 55 224 5.6E-24 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HL41_02220 e9575fa50c1fa169918cf5df0b660d2e 323 SUPERFAMILY SSF52518 18 312 2.95E-78 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold HL41_02220 e9575fa50c1fa169918cf5df0b660d2e 323 Gene3D G3DSA:3.40.50.970 104 313 1.1E-65 T 14-10-2018 HL41_02220 e9575fa50c1fa169918cf5df0b660d2e 323 Gene3D G3DSA:3.40.50.970 7 103 6.1E-14 T 14-10-2018 HL41_01840 cea6dffe50570cb3640ffb33f7dca815 627 SUPERFAMILY SSF48452 252 355 1.68E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_08145 33b5fbe765843a01e0e250afcf1bd86f 188 Hamap MF_02089 Epoxyqueuosine reductase QueH [queH]. 2 174 30.306 T 14-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 HL41_08145 33b5fbe765843a01e0e250afcf1bd86f 188 Pfam PF02677 Uncharacterized BCR, COG1636 2 173 5.0E-54 T 14-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 HL41_06885 14ae5e687cdc3bdfc9cc196567223d90 127 Pfam PF12978 Domain of Unknown Function with PDB structure (DUF3862) 62 124 2.1E-6 T 14-10-2018 IPR024418 Protein of unknown function DUF3862 HL41_06885 14ae5e687cdc3bdfc9cc196567223d90 127 Gene3D G3DSA:3.30.1450.10 58 126 4.1E-8 T 14-10-2018 IPR037873 BamE-like HL41_08620 55ce5bea2c92002819443d23ad2433f8 218 SUPERFAMILY SSF103501 6 211 7.32E-29 T 14-10-2018 IPR036197 NarG-like superfamily HL41_08620 55ce5bea2c92002819443d23ad2433f8 218 Gene3D G3DSA:1.20.950.20 60 168 6.2E-6 T 14-10-2018 HL41_08620 55ce5bea2c92002819443d23ad2433f8 218 Pfam PF02665 Nitrate reductase gamma subunit 70 164 3.7E-5 T 14-10-2018 IPR023234 NarG-like domain HL41_00930 3e6b0f7fccf9f70e6b483f556dbad8fd 171 SUPERFAMILY SSF103256 2 134 7.45E-46 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 HL41_00930 3e6b0f7fccf9f70e6b483f556dbad8fd 171 Gene3D G3DSA:3.10.690.10 1 142 1.1E-51 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 HL41_00930 3e6b0f7fccf9f70e6b483f556dbad8fd 171 Pfam PF02577 Bifunctional nuclease 8 132 5.1E-47 T 14-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 HL41_09150 efb9ebf8697b6ab53f21e2af9dd3ea64 235 Pfam PF03692 Putative zinc- or iron-chelating domain 19 116 1.9E-7 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein HL41_01035 19c7ace10a23336f5013d13fbfc87003 128 Pfam PF10865 Domain of unknown function (DUF2703) 4 114 3.1E-12 T 14-10-2018 IPR021219 Protein of unknown function DUF2703 HL41_00470 0ef92fcbf3bd0044b46fc3a608b32ae8 326 Gene3D G3DSA:3.90.25.10 180 310 4.5E-99 T 14-10-2018 HL41_00470 0ef92fcbf3bd0044b46fc3a608b32ae8 326 Gene3D G3DSA:3.40.50.720 5 298 4.5E-99 T 14-10-2018 HL41_00470 0ef92fcbf3bd0044b46fc3a608b32ae8 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 243 7.2E-58 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HL41_00470 0ef92fcbf3bd0044b46fc3a608b32ae8 326 PRINTS PR01713 Nucleotide sugar epimerase signature 30 46 1.7E-15 T 14-10-2018 HL41_00470 0ef92fcbf3bd0044b46fc3a608b32ae8 326 PRINTS PR01713 Nucleotide sugar epimerase signature 277 294 1.7E-15 T 14-10-2018 HL41_00470 0ef92fcbf3bd0044b46fc3a608b32ae8 326 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 1.7E-15 T 14-10-2018 HL41_00470 0ef92fcbf3bd0044b46fc3a608b32ae8 326 PRINTS PR01713 Nucleotide sugar epimerase signature 237 252 1.7E-15 T 14-10-2018 HL41_00470 0ef92fcbf3bd0044b46fc3a608b32ae8 326 SUPERFAMILY SSF51735 2 315 1.94E-90 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily HL41_04015 62012f5494df8721497f5a6ea3f357bb 130 Gene3D G3DSA:1.20.120.340 1 125 3.8E-37 T 14-10-2018 HL41_04015 62012f5494df8721497f5a6ea3f357bb 130 TIGRFAM TIGR00208 fliS: flagellar protein FliS 5 121 1.5E-20 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 HL41_04015 62012f5494df8721497f5a6ea3f357bb 130 PIRSF PIRSF039090 2 130 3.7E-28 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 HL41_04015 62012f5494df8721497f5a6ea3f357bb 130 SUPERFAMILY SSF101116 4 121 1.7E-29 T 14-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 HL41_04015 62012f5494df8721497f5a6ea3f357bb 130 Pfam PF02561 Flagellar protein FliS 4 120 2.9E-33 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 HL41_07045 f604f8ca194cdcf975f5058125288b41 365 Pfam PF04865 Baseplate J-like protein 66 323 3.2E-65 T 14-10-2018 IPR006949 Baseplate protein J-like HL41_07045 f604f8ca194cdcf975f5058125288b41 365 PIRSF PIRSF020481 7 364 2.3E-58 T 14-10-2018 IPR014507 Baseplate assembly protein J, predicted HL41_08300 08799e35b13a8e6b43990844c21340e5 419 Pfam PF01925 Sulfite exporter TauE/SafE 79 356 3.6E-38 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HL41_04750 1dc78924ae153c864f5ec0eb0cbfc3c3 184 Pfam PF09918 Uncharacterized protein containing a ferredoxin domain (DUF2148) 115 180 1.1E-31 T 14-10-2018 IPR019224 Protein of unknown function DUF2148 HL41_04750 1dc78924ae153c864f5ec0eb0cbfc3c3 184 SUPERFAMILY SSF55469 11 104 1.41E-5 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HL41_03235 d31e201eb0ba08e5f5ffca758591bc6b 117 Pfam PF07238 PilZ domain 6 104 8.9E-14 T 14-10-2018 IPR009875 PilZ domain GO:0035438 HL41_03235 d31e201eb0ba08e5f5ffca758591bc6b 117 SUPERFAMILY SSF141371 4 106 1.06E-13 T 14-10-2018 HL41_03235 d31e201eb0ba08e5f5ffca758591bc6b 117 Gene3D G3DSA:2.40.10.220 2 115 4.8E-16 T 14-10-2018 HL41_01265 7211e9096f25ced6bcbc109a17a293c7 458 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 22 369 2.2E-104 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HL41_01265 7211e9096f25ced6bcbc109a17a293c7 458 Pfam PF13742 OB-fold nucleic acid binding domain 21 115 8.9E-25 T 14-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 HL41_01265 7211e9096f25ced6bcbc109a17a293c7 458 Pfam PF02601 Exonuclease VII, large subunit 136 450 8.4E-86 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 HL41_01265 7211e9096f25ced6bcbc109a17a293c7 458 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 18 454 22.539 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HL41_06915 7e5f08ba385791b8b43732998f54a690 166 Gene3D G3DSA:1.10.10.10 3 60 3.5E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily HL41_06915 7e5f08ba385791b8b43732998f54a690 166 SUPERFAMILY SSF46955 2 57 3.42E-8 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily HL41_02910 31368ad8718e0f264897cc8b9d39c435 221 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 28 127 2.2E-37 T 14-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative HL41_06755 4ee5a1b902846f7202afb942fbf949c5 206 SUPERFAMILY SSF58104 26 174 5.75E-8 T 14-10-2018 HL41_03940 e43753ad986e91e66d61314e49fdf012 172 Pfam PF07012 Curlin associated repeat 39 70 1.8E-6 T 14-10-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 HL41_01695 c852ddd723bdf585a80e04310da3e3d1 180 Pfam PF05137 Fimbrial assembly protein (PilN) 117 178 4.9E-6 T 14-10-2018 IPR007813 Fimbrial assembly PilN HL41_00400 bba4799b4e186658aae2ec0e6c800c81 177 Pfam PF14385 Domain of unknown function (DUF4416) 10 168 6.4E-53 T 14-10-2018 IPR025529 Protein of unknown function DUF4416 HL41_08270 689a4ec5e6fdd679f43ec8b9fdb9ea21 576 Pfam PF03600 Citrate transporter 151 519 4.8E-46 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 HL41_08270 689a4ec5e6fdd679f43ec8b9fdb9ea21 576 PRINTS PR00758 Arsenical pump membrane protein signature 247 271 4.8E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HL41_08270 689a4ec5e6fdd679f43ec8b9fdb9ea21 576 PRINTS PR00758 Arsenical pump membrane protein signature 320 343 4.8E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HL41_08270 689a4ec5e6fdd679f43ec8b9fdb9ea21 576 PRINTS PR00758 Arsenical pump membrane protein signature 515 540 4.8E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HL41_08270 689a4ec5e6fdd679f43ec8b9fdb9ea21 576 PRINTS PR00758 Arsenical pump membrane protein signature 427 451 4.8E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 HL41_05725 a457974756da62e0d67840c1cdfa7c59 356 SUPERFAMILY SSF48371 172 322 2.3E-10 T 14-10-2018 IPR016024 Armadillo-type fold HL41_02775 f3a97faebc431751469bd4946807e18e 336 Gene3D G3DSA:1.10.3870.10 16 207 5.5E-93 T 14-10-2018 HL41_02775 f3a97faebc431751469bd4946807e18e 336 Gene3D G3DSA:3.40.50.1000 7 284 5.5E-93 T 14-10-2018 IPR023214 HAD superfamily HL41_02775 f3a97faebc431751469bd4946807e18e 336 SUPERFAMILY SSF56784 4 289 4.46E-24 T 14-10-2018 IPR036412 HAD-like superfamily HL41_04295 d571f68689f2a98d89cea8d5f36fdac0 260 Pfam PF13103 TonB C terminal 171 242 4.1E-12 T 14-10-2018 HL41_04295 d571f68689f2a98d89cea8d5f36fdac0 260 SUPERFAMILY SSF74653 158 252 8.5E-11 T 14-10-2018 HL41_04295 d571f68689f2a98d89cea8d5f36fdac0 260 Gene3D G3DSA:3.30.1150.10 162 256 6.3E-11 T 14-10-2018 HL41_03170 e2f6607ff623c9936b01ff16c1c6f994 295 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 271 8.0E-33 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD HL41_03170 e2f6607ff623c9936b01ff16c1c6f994 295 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 15 176 2.2E-12 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD HL41_01700 8d965749c40a1cde811f24e04dc9911c 199 Gene3D G3DSA:3.30.70.60 92 197 1.5E-21 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 HL41_01700 8d965749c40a1cde811f24e04dc9911c 199 Pfam PF04350 Pilus assembly protein, PilO 50 186 1.9E-24 T 14-10-2018 IPR007445 Pilus assembly protein, PilO HL41_07735 e70de195af4c76a9bae93b348898896c 265 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 5 45 7.8E-13 T 14-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal HL41_07735 e70de195af4c76a9bae93b348898896c 265 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 12 84 2.7E-6 T 14-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 HL41_00155 353a4edb973e369741e938583aad9ba6 366 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 349 1.4E-52 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 HL41_00990 1dfc61cddfd715cce83d6825c7e27814 109 SUPERFAMILY SSF140566 6 84 6.41E-5 T 14-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 HL41_04070 240b04a3c68aba3089fde41283ff4737 80 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 72 1.0E-15 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HL41_04070 240b04a3c68aba3089fde41283ff4737 80 SMART SM01234 1 72 1.0E-38 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HL41_04070 240b04a3c68aba3089fde41283ff4737 80 Pfam PF01809 Haemolytic domain 4 72 2.9E-29 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HL41_04070 240b04a3c68aba3089fde41283ff4737 80 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 73 23.928 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HL41_04070 240b04a3c68aba3089fde41283ff4737 80 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 76 6.2E-27 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor HL41_06265 72be7debdbe884520bd4652aeb6ca756 356 Pfam PF00953 Glycosyl transferase family 4 71 227 1.2E-28 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 HL41_01225 09bf1a171799f42812477d3bc9719cbe 150 Pfam PF01927 Mut7-C RNAse domain 3 144 4.7E-25 T 14-10-2018 IPR002782 Mut7-C RNAse domain HL41_07565 32badc36c5480b3ad0faee2c4ba53828 294 Pfam PF02646 RmuC family 23 270 3.0E-14 T 14-10-2018 IPR003798 DNA recombination RmuC HL41_03470 17135c0b3f07bedb52097029c24f108f 239 TIGRFAM TIGR00608 radc: DNA repair protein RadC 15 227 1.4E-63 T 14-10-2018 IPR001405 Uncharacterised protein family UPF0758 HL41_03470 17135c0b3f07bedb52097029c24f108f 239 SUPERFAMILY SSF102712 155 193 5.75E-5 T 14-10-2018 HL41_03470 17135c0b3f07bedb52097029c24f108f 239 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 176 181 - T 14-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site HL41_03470 17135c0b3f07bedb52097029c24f108f 239 Pfam PF04002 RadC-like JAB domain 107 225 1.8E-45 T 14-10-2018 IPR025657 RadC-like JAB domain HL41_03470 17135c0b3f07bedb52097029c24f108f 239 Gene3D G3DSA:3.40.140.10 103 226 5.8E-46 T 14-10-2018 HL41_03470 17135c0b3f07bedb52097029c24f108f 239 SUPERFAMILY SSF47781 46 83 3.51E-5 T 14-10-2018 IPR010994 RuvA domain 2-like HL41_03885 943df09dcf05199226317a881a853037 119 Pfam PF05818 Enterobacterial TraT complement resistance protein 6 119 4.1E-21 T 14-10-2018 IPR008874 Enterobacterial TraT complement resistance GO:0019867|GO:0046999 HL41_00665 41d25041c98672ef15ee009279dea5a5 255 Pfam PF02591 C4-type zinc ribbon domain 198 229 1.1E-11 T 14-10-2018 IPR003743 C4-type zinc ribbon domain HL41_03515 5e491935b32f948bd31a5d790363c517 470 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 51 210 2.2E-29 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like HL41_02715 0f0fc8972dd324e9dd53da1660e0ccae 255 Pfam PF01925 Sulfite exporter TauE/SafE 11 246 1.4E-42 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HL41_00720 c8d01af0600e3481ca70a6a1b158bf3c 90 Pfam PF08899 Domain of unknown function (DUF1844) 13 85 1.6E-29 T 14-10-2018 IPR014995 Protein of unknown function DUF1844 HL41_02535 337bdb1d101ed11a717b62b699475526 273 Pfam PF02596 Uncharacterised ArCR, COG2043 4 255 2.7E-61 T 14-10-2018 IPR003748 Protein of unknown function DUF169 HL41_04215 2c4369f34fd566efc932159a5b1fc71e 326 Gene3D G3DSA:3.30.70.3460 194 325 1.5E-33 T 14-10-2018 HL41_04215 2c4369f34fd566efc932159a5b1fc71e 326 Gene3D G3DSA:3.30.70.3460 63 169 5.2E-21 T 14-10-2018 HL41_07030 fbf72b8f305489cb7201655cb772b0cc 435 Pfam PF04233 Phage Mu protein F like protein 168 275 6.3E-8 T 14-10-2018 IPR006528 Phage head morphogenesis domain HL41_08115 e595e8649857541ec7ad9e39ffee56c8 308 Gene3D G3DSA:1.10.287.110 245 307 1.2E-5 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_08115 e595e8649857541ec7ad9e39ffee56c8 308 SUPERFAMILY SSF46565 255 302 3.01E-6 T 14-10-2018 IPR036869 Chaperone J-domain superfamily HL41_03930 cd8fb7599c2d1b6e4176b78acde8cb36 128 Pfam PF10627 Curli assembly protein CsgE 26 118 4.5E-21 T 14-10-2018 IPR018900 Curli assembly protein CsgE HL41_06350 c3c6ed2aa07cdd761c25591abc10621b 72 Pfam PF10047 Protein of unknown function (DUF2281) 6 64 2.1E-16 T 14-10-2018 IPR018739 Domain of unknown function DUF2281 HL41_02185 b7edc562d19404eaa851166c1da94803 238 Pfam PF10670 Domain of unknown function (DUF4198) 36 201 1.4E-11 T 14-10-2018 IPR019613 Protein of unknown function DUF4198 HL41_06550 95fee1cb20560774b50cb6b2ba8aa0bd 275 Pfam PF01578 Cytochrome C assembly protein 66 271 1.1E-32 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 HL41_07890 adb566b94da2343480ff907decc271d4 519 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 74 219 4.9E-8 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like HL41_00520 a8e6cc14c892d4c38fa432bcff894d55 620 Gene3D G3DSA:1.25.40.10 284 559 4.0E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_00520 a8e6cc14c892d4c38fa432bcff894d55 620 Gene3D G3DSA:1.25.40.10 46 253 6.1E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 HL41_04260 23c1680240cc35536ff3c000dd3725c2 178 Pfam PF04390 Lipopolysaccharide-assembly 36 170 8.6E-11 T 14-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 HL41_03925 4fafcef11c1c879e06d492d67d17ba5e 143 Pfam PF10614 Type VIII secretion system (T8SS), CsgF protein 10 138 8.2E-36 T 14-10-2018 IPR018893 Type VIII secretion system, CsgF HL41_08140 ec710a2a057a7e6c43b2f941960aaef7 404 Pfam PF00999 Sodium/hydrogen exchanger family 13 396 1.7E-74 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HL41_08140 ec710a2a057a7e6c43b2f941960aaef7 404 Gene3D G3DSA:1.20.1530.20 7 400 3.3E-92 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily HL41_02035 033a9f75beeb777c3568df540e15845e 413 Gene3D G3DSA:3.30.2010.10 172 257 2.6E-10 T 14-10-2018 HL41_02035 033a9f75beeb777c3568df540e15845e 413 Pfam PF01435 Peptidase family M48 179 348 7.0E-15 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HL41_01635 610380896b136a175b0199de8d112d9f 128 SUPERFAMILY SSF48695 82 119 1.77E-6 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily HL41_08460 219072fdd6d60ec44d8b1312284bc772 134 Pfam PF01925 Sulfite exporter TauE/SafE 14 127 6.5E-20 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HL41_03900 a219660fffc8ab6d3a9d7ad4168c1004 885 Pfam PF04465 Protein of unknown function (DUF499) 526 748 5.1E-12 T 14-10-2018 IPR007555 Protein of unknown function DUF499 HL41_03900 a219660fffc8ab6d3a9d7ad4168c1004 885 Pfam PF04465 Protein of unknown function (DUF499) 131 512 8.0E-41 T 14-10-2018 IPR007555 Protein of unknown function DUF499 HL41_02285 5d24f624fc5504688951482c3ad23658 258 Pfam PF02535 ZIP Zinc transporter 107 253 5.4E-18 T 14-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 HL41_02685 5db029b443d17bad0201396773b258ed 366 Gene3D G3DSA:3.80.30.30 110 331 2.2E-50 T 14-10-2018 HL41_06175 8eed78136d2cc79ab751862831d3b4d3 109 Pfam PF04977 Septum formation initiator 46 98 7.3E-8 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC HL41_04125 8c3ddddd485311591c8cec2059d90494 163 Pfam PF06146 Phosphate-starvation-inducible E 72 138 4.6E-9 T 14-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like HL41_03935 5e5af4ce7352246a00f2d899547e6274 132 Gene3D G3DSA:2.60.40.2420 34 130 1.2E-10 T 14-10-2018 HL41_07375 e1767120152b199fae1d4f3912c76cb0 309 Pfam PF00146 NADH dehydrogenase 17 303 1.5E-46 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HL41_01610 38f88a532881b943c0d88ab116104d81 471 Pfam PF03961 Flagellar Assembly Protein A 19 463 4.1E-75 T 14-10-2018 IPR005646 Flagellar assembly protein A HL41_02305 ecf3b54826a1dfb6267c2525defa3f35 262 Pfam PF02698 DUF218 domain 90 251 9.6E-16 T 14-10-2018 IPR003848 Domain of unknown function DUF218 HL41_04210 d94590bfef399f42fe1cfb3a480936ad 301 Pfam PF01925 Sulfite exporter TauE/SafE 32 293 9.1E-36 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HL41_06105 af2bc1efee0c3428898bb73f31eaf3cc 100 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 100 18.072 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 HL41_06105 af2bc1efee0c3428898bb73f31eaf3cc 100 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 95 1.3E-21 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like HL41_02630 57633d8ea5c7e3473a0b2bfeb724f12b 83 Pfam PF04347 Flagellar biosynthesis protein, FliO 31 80 7.9E-6 T 14-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 HL41_00790 7d6763dc218160be39dd6924057ddd8b 403 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 60 211 2.7E-10 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like HL41_02510 3c4c1ef4349f967c6ca3fabc38321379 425 Pfam PF03773 Predicted permease 35 421 9.8E-65 T 14-10-2018 IPR005524 Predicted permease DUF318 HL41_00710 c70bd709da3774880433c6e0edd498f5 368 Pfam PF01594 AI-2E family transporter 17 350 4.4E-52 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like HL41_03890 2b7d41a75e1837ddee02f373809eb0bc 145 Gene3D G3DSA:3.30.160.670 32 144 2.2E-5 T 14-10-2018 HL41_03890 2b7d41a75e1837ddee02f373809eb0bc 145 Pfam PF05818 Enterobacterial TraT complement resistance protein 40 127 8.3E-25 T 14-10-2018 IPR008874 Enterobacterial TraT complement resistance GO:0019867|GO:0046999 HL41_07075 d7a62f29055a76147057d7c5939004dc 109 Pfam PF05135 Phage gp6-like head-tail connector protein 1 60 2.2E-4 T 14-10-2018 IPR021146 Phage gp6-like head-tail connector protein HL41_08050 4dca1fb45a9a22091b71ea11c5c8d8cd 117 Pfam PF13701 Transposase DDE domain group 1 53 107 4.2E-8 T 14-10-2018 IPR025668 Transposase DDE domain HL41_03125 eb4f4dae2ba1f8419039056aa86a1903 366 Pfam PF11306 Protein of unknown function (DUF3108) 157 363 3.3E-9 T 14-10-2018 IPR021457 Protein of unknown function DUF3108 HL41_08875 67e572aaa031fcec0ae3122377140c47 278 Pfam PF10670 Domain of unknown function (DUF4198) 123 236 1.0E-11 T 14-10-2018 IPR019613 Protein of unknown function DUF4198 HL41_04565 60a6cfb927e3d7ad23c358f64d77f571 241 Pfam PF07277 SapC 14 228 3.0E-42 T 14-10-2018 IPR010836 SapC HL41_06540 6bd8a3e5ff8c20d612fb431e7e3a7327 371 Pfam PF12698 ABC-2 family transporter protein 20 362 6.0E-33 T 14-10-2018 HL41_07245 b5537675b4ee98dbe427c2361031acce 362 Pfam PF05559 Protein of unknown function (DUF763) 6 321 3.8E-120 T 14-10-2018 IPR008482 Protein of unknown function DUF763 HL41_06970 98640e2cb6fd29b304b70f3d67c97f4d 173 Pfam PF06995 Phage P2 GpU 7 122 1.3E-17 T 14-10-2018 IPR009734 Myoviridae, GpU HL41_00985 ca94d41ab6667de2bd37faf6fa12f4d6 106 Pfam PF10135 Rod binding protein 48 88 6.2E-5 T 14-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal HL41_02975 0f2d805abd81721e935dfdee3dbc3fc1 141 Pfam PF02371 Transposase IS116/IS110/IS902 family 16 86 1.4E-18 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313