locus-tag	class	description
TOPB45_0002	PF02913	FAD linked oxidases, C-terminal domain
TOPB45_0002	PF01565	FAD binding domain 
TOPB45_0003	PF01171	PP-loop family
TOPB45_0004	PF01464	Transglycosylase SLT domain
TOPB45_0005	PF00924	Mechanosensitive ion channel
TOPB45_0005	PF05552	Conserved TM helix
TOPB45_0010	PF06750	Bacterial Peptidase A24 N-terminal domain
TOPB45_0010	PF01478	Type IV leader peptidase family
TOPB45_0012	PF03853	YjeF-related protein N-terminus
TOPB45_0012	PF01256	Carbohydrate kinase
TOPB45_0013	PF01648	4'-phosphopantetheinyl transferase superfamily
TOPB45_0014	PF02502	Ribose/Galactose Isomerase
TOPB45_0015	PF00109	Beta-ketoacyl synthase, N-terminal domain
TOPB45_0015	PF02801	Beta-ketoacyl synthase, C-terminal domain
TOPB45_0016	PF00550	Phosphopantetheine attachment site
TOPB45_0019	PF06969	HemN C-terminal domain
TOPB45_0019	PF04055	Radical SAM superfamily
TOPB45_0020	PF05175	Methyltransferase small domain
TOPB45_0022	PF04055	Radical SAM superfamily
TOPB45_0023	PF01842	ACT domain
TOPB45_0023	PF02826	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
TOPB45_0023	PF00389	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
TOPB45_0024	PF00266	Aminotransferase class-V
TOPB45_0025	PF03449	Transcription elongation factor, N-terminal
TOPB45_0025	PF01272	Transcription elongation factor, GreA/GreB, C-term
TOPB45_0026	PF02142	MGS-like domain
TOPB45_0026	PF01808	AICARFT/IMPCHase bienzyme
TOPB45_0027	PF02684	Lipid-A-disaccharide synthetase
TOPB45_0030	PF00132	Bacterial transferase hexapeptide (six repeats)
TOPB45_0030	PF13720	Udp N-acetylglucosamine O-acyltransferase; Domain 2
TOPB45_0031	PF07977	FabA-like domain
TOPB45_0034	PF00005	ABC transporter
TOPB45_0035	PF02405	Permease MlaE
TOPB45_0036	PF00920	Dehydratase family
TOPB45_0037	PF01106	NifU-like domain
TOPB45_0038	PF01192	RNA polymerase Rpb6 
TOPB45_0039	PF00226	DnaJ domain
TOPB45_0039	PF01556	DnaJ C terminal domain
TOPB45_0039	PF00684	DnaJ central domain
TOPB45_0040	PF01967	MoaC family
TOPB45_0042	PF17755	UvrA DNA-binding domain
TOPB45_0042	PF00005	ABC transporter
TOPB45_0042	PF17760	UvrA interaction domain
TOPB45_0043	PF00571	CBS domain
TOPB45_0043	PF00478	IMP dehydrogenase / GMP reductase domain
TOPB45_0046	PF13288	DXP reductoisomerase C-terminal domain
TOPB45_0046	PF02670	1-deoxy-D-xylulose 5-phosphate reductoisomerase
TOPB45_0046	PF08436	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain
TOPB45_0047	PF17820	PDZ domain
TOPB45_0047	PF02163	Peptidase family M50
TOPB45_0048	PF00814	Glycoprotease family
TOPB45_0049	PF00528	Binding-protein-dependent transport system inner membrane component
TOPB45_0050	PF12911	N-terminal TM domain of oligopeptide transport permease C
TOPB45_0050	PF00528	Binding-protein-dependent transport system inner membrane component
TOPB45_0054	PF00158	Sigma-54 interaction domain
TOPB45_0054	PF02954	Bacterial regulatory protein, Fis family
TOPB45_0054	PF13185	GAF domain
TOPB45_0056	PF02954	Bacterial regulatory protein, Fis family
TOPB45_0056	PF00072	Response regulator receiver domain
TOPB45_0056	PF00158	Sigma-54 interaction domain
TOPB45_0057	PF00460	Flagella basal body rod protein
TOPB45_0058	PF00460	Flagella basal body rod protein
TOPB45_0058	PF06429	Flagellar basal body rod FlgEFG protein C-terminal
TOPB45_0059	PF02049	Flagellar hook-basal body complex protein FliE
TOPB45_0060	PF01514	Secretory protein of YscJ/FliF family
TOPB45_0060	PF08345	Flagellar M-ring protein C-terminal
TOPB45_0061	PF14841	FliG middle domain
TOPB45_0061	PF01706	FliG C-terminal domain
TOPB45_0061	PF14842	FliG N-terminal domain
TOPB45_0063	PF18269	T3SS EscN ATPase C-terminal domain
TOPB45_0063	PF02874	ATP synthase alpha/beta family, beta-barrel domain
TOPB45_0063	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain
TOPB45_0066	PF00902	Sec-independent protein translocase protein (TatC)
TOPB45_0069	PF00216	Bacterial DNA-binding protein
TOPB45_0070	PF06827	Zinc finger found in FPG and IleRS
TOPB45_0070	PF01149	Formamidopyrimidine-DNA glycosylase N-terminal domain
TOPB45_0070	PF06831	Formamidopyrimidine-DNA glycosylase H2TH domain
TOPB45_0071	PF01594	AI-2E family transporter
TOPB45_0074	PF08544	GHMP kinases C terminal 
TOPB45_0074	PF00288	GHMP kinases N terminal domain
TOPB45_0075	PF14572	Phosphoribosyl synthetase-associated domain
TOPB45_0075	PF13793	N-terminal domain of ribose phosphate pyrophosphokinase
TOPB45_0076	PF01386	Ribosomal L25p family
TOPB45_0076	PF14693	Ribosomal protein TL5, C-terminal domain
TOPB45_0077	PF01195	Peptidyl-tRNA hydrolase
TOPB45_0079	PF02540	NAD synthase
TOPB45_0079	PF00117	Glutamine amidotransferase class-I
TOPB45_0079	PF00958	GMP synthase C terminal domain
TOPB45_0083	PF01783	Ribosomal L32p protein family
TOPB45_0084	PF02504	Fatty acid synthesis protein
TOPB45_0085	PF08541	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal  
TOPB45_0085	PF08545	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
TOPB45_0086	PF07559	Flagellar basal body protein FlaE
TOPB45_0086	PF00460	Flagella basal body rod protein
TOPB45_0086	PF06429	Flagellar basal body rod FlgEFG protein C-terminal
TOPB45_0087	PF06429	Flagellar basal body rod FlgEFG protein C-terminal
TOPB45_0087	PF00460	Flagella basal body rod protein
TOPB45_0087	PF07559	Flagellar basal body protein FlaE
TOPB45_0088	PF03963	Flagellar hook capping protein - N-terminal region
TOPB45_0090	PF00361	Proton-conducting membrane transporter
TOPB45_0091	PF01059	NADH-ubiquinone oxidoreductase chain 4, amino terminus
TOPB45_0091	PF00361	Proton-conducting membrane transporter
TOPB45_0092	PF00662	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
TOPB45_0092	PF00361	Proton-conducting membrane transporter
TOPB45_0093	PF00420	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
TOPB45_0094	PF00499	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
TOPB45_0095	PF12838	4Fe-4S dicluster domain
TOPB45_0096	PF00146	NADH dehydrogenase
TOPB45_0097	PF00346	Respiratory-chain NADH dehydrogenase, 49 Kd subunit
TOPB45_0098	PF00329	Respiratory-chain NADH dehydrogenase, 30 Kd subunit
TOPB45_0099	PF01058	NADH ubiquinone oxidoreductase, 20 Kd subunit
TOPB45_0100	PF00507	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
TOPB45_0101	PF13247	4Fe-4S dicluster domain
TOPB45_0101	PF12800	4Fe-4S binding domain
TOPB45_0103	PF13380	CoA binding domain
TOPB45_0104	PF00121	Triosephosphate isomerase
TOPB45_0105	PF00162	Phosphoglycerate kinase
TOPB45_0106	PF00885	6,7-dimethyl-8-ribityllumazine synthase
TOPB45_0109	PF01326	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
TOPB45_0109	PF00391	PEP-utilising enzyme, mobile domain
TOPB45_0109	PF02896	PEP-utilising enzyme, TIM barrel domain
TOPB45_0110	PF01668	SmpB protein
TOPB45_0111	PF13476	AAA domain
TOPB45_0112	PF12804	MobA-like NTP transferase domain
TOPB45_0113	PF01966	HD domain
TOPB45_0113	PF00072	Response regulator receiver domain
TOPB45_0117	PF02621	Menaquinone biosynthesis
TOPB45_0118	PF01618	MotA/TolQ/ExbB proton channel family
TOPB45_0119	PF00085	Thioredoxin
TOPB45_0120	PF13525	Outer membrane lipoprotein
TOPB45_0122	PF07517	SecA DEAD-like domain
TOPB45_0122	PF01043	SecA preprotein cross-linking domain
TOPB45_0122	PF02810	SEC-C motif
TOPB45_0122	PF07516	SecA Wing and Scaffold domain
TOPB45_0123	PF01142	tRNA pseudouridine synthase D (TruD)
TOPB45_0124	PF01075	Glycosyltransferase family 9 (heptosyltransferase)
TOPB45_0126	PF00591	Glycosyl transferase family, a/b domain
TOPB45_0126	PF02885	Glycosyl transferase family, helical bundle domain
TOPB45_0127	PF01523	Putative modulator of DNA gyrase
TOPB45_0128	PF00113	Enolase, C-terminal TIM barrel domain
TOPB45_0128	PF03952	Enolase, N-terminal domain
TOPB45_0129	PF00294	pfkB family carbohydrate kinase
TOPB45_0129	PF01467	Cytidylyltransferase-like
TOPB45_0130	PF00154	recA bacterial DNA recombination protein
TOPB45_0132	PF12320	Type 5 capsule protein repressor C-terminal domain
TOPB45_0132	PF00149	Calcineurin-like phosphoesterase
TOPB45_0133	PF01113	Dihydrodipicolinate reductase, N-terminus
TOPB45_0133	PF05173	Dihydrodipicolinate reductase, C-terminus
TOPB45_0134	PF10609	NUBPL iron-transfer P-loop NTPase
TOPB45_0137	PF01177	Asp/Glu/Hydantoin racemase
TOPB45_0138	PF00202	Aminotransferase class-III
TOPB45_0139	PF04055	Radical SAM superfamily
TOPB45_0139	PF18693	TRAM domain
TOPB45_0139	PF00919	Uncharacterized protein family UPF0004
TOPB45_0142	PF00753	Metallo-beta-lactamase superfamily
TOPB45_0144	PF04493	Endonuclease V
TOPB45_0145	PF02384	N-6 DNA Methylase
TOPB45_0148	PF01420	Type I restriction modification DNA specificity domain
TOPB45_0151	PF11867	Domain of unknown function (DUF3387)
TOPB45_0151	PF04313	Type I restriction enzyme R protein N terminus (HSDR_N)
TOPB45_0151	PF18766	SWI2/SNF2 ATPase
TOPB45_0152	PF01741	Large-conductance mechanosensitive channel, MscL
TOPB45_0154	PF00258	Flavodoxin
TOPB45_0154	PF01613	Flavin reductase like domain
TOPB45_0156	PF09350	Domain of unknown function (DUF1992)
TOPB45_0157	PF01872	RibD C-terminal domain
TOPB45_0157	PF00383	Cytidine and deoxycytidylate deaminase zinc-binding region
TOPB45_0158	PF01121	Dephospho-CoA kinase
TOPB45_0159	PF00849	RNA pseudouridylate synthase
TOPB45_0159	PF01479	S4 domain
TOPB45_0161	PF08525	Opacity-associated protein A N-terminal motif
TOPB45_0161	PF01476	LysM domain
TOPB45_0161	PF01551	Peptidase family M23
TOPB45_0162	PF00312	Ribosomal protein S15
TOPB45_0163	PF04997	RNA polymerase Rpb1, domain 1
TOPB45_0163	PF04983	RNA polymerase Rpb1, domain 3
TOPB45_0163	PF04998	RNA polymerase Rpb1, domain 5
TOPB45_0163	PF05000	RNA polymerase Rpb1, domain 4
TOPB45_0163	PF00623	RNA polymerase Rpb1, domain 2
TOPB45_0164	PF10385	RNA polymerase beta subunit external 1 domain
TOPB45_0164	PF00562	RNA polymerase Rpb2, domain 6
TOPB45_0164	PF04565	RNA polymerase Rpb2, domain 3
TOPB45_0164	PF04561	RNA polymerase Rpb2, domain 2
TOPB45_0164	PF04563	RNA polymerase beta subunit
TOPB45_0164	PF04560	RNA polymerase Rpb2, domain 7
TOPB45_0165	PF00542	Ribosomal protein L7/L12 C-terminal domain
TOPB45_0165	PF16320	Ribosomal protein L7/L12 dimerisation domain
TOPB45_0166	PF00466	Ribosomal protein L10
TOPB45_0167	PF00687	Ribosomal protein L1p/L10e family
TOPB45_0168	PF00298	Ribosomal protein L11, RNA binding domain
TOPB45_0168	PF03946	Ribosomal protein L11, N-terminal domain
TOPB45_0169	PF02357	Transcription termination factor nusG
TOPB45_0169	PF00467	KOW motif
TOPB45_0170	PF00584	SecE/Sec61-gamma subunits of protein translocation complex
TOPB45_0171	PF00471	Ribosomal protein L33
TOPB45_0172	PF03143	Elongation factor Tu C-terminal domain
TOPB45_0172	PF03144	Elongation factor Tu domain 2
TOPB45_0172	PF00009	Elongation factor Tu GTP binding domain
TOPB45_0174	PF01593	Flavin containing amine oxidoreductase
TOPB45_0175	PF14537	Cytochrome c3
TOPB45_0175	PF00890	FAD binding domain
TOPB45_0176	PF00890	FAD binding domain
TOPB45_0177	PF12139	Adenosine-5'-phosphosulfate reductase beta subunit
TOPB45_0177	PF13187	4Fe-4S dicluster domain
TOPB45_0179	PF01747	ATP-sulfurylase
TOPB45_0179	PF14306	PUA-like domain
TOPB45_0180	PF00348	Polyprenyl synthetase
TOPB45_0182	PF00580	UvrD/REP helicase N-terminal domain
TOPB45_0182	PF13361	UvrD-like helicase C-terminal domain
TOPB45_0183	PF04452	RNA methyltransferase
TOPB45_0186	PF00582	Universal stress protein family
TOPB45_0187	PF03796	DnaB-like helicase C terminal domain
TOPB45_0187	PF00772	DnaB-like helicase N terminal domain
TOPB45_0188	PF01281	Ribosomal protein L9, N-terminal domain
TOPB45_0188	PF03948	Ribosomal protein L9, C-terminal domain
TOPB45_0189	PF01084	Ribosomal protein S18
TOPB45_0190	PF01250	Ribosomal protein S6
TOPB45_0191	PF00293	NUDIX domain
TOPB45_0192	PF00206	Lyase
TOPB45_0192	PF10397	Adenylosuccinate lyase C-terminus
TOPB45_0193	PF00877	NlpC/P60 family
TOPB45_0193	PF01476	LysM domain
TOPB45_0194	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_0194	PF07694	5TMR of 5TMR-LYT
TOPB45_0196	PF01380	SIS domain
TOPB45_0196	PF00571	CBS domain
TOPB45_0197	PF02223	Thymidylate kinase
TOPB45_0200	PF01139	tRNA-splicing ligase RtcB
TOPB45_0201	PF00227	Proteasome subunit
TOPB45_0202	PF07724	AAA domain (Cdc48 subfamily)
TOPB45_0202	PF10431	C-terminal, D2-small domain, of ClpB protein 
TOPB45_0203	PF00919	Uncharacterized protein family UPF0004
TOPB45_0203	PF04055	Radical SAM superfamily
TOPB45_0203	PF18693	TRAM domain
TOPB45_0204	PF02261	Aspartate decarboxylase
TOPB45_0205	PF02569	Pantoate-beta-alanine ligase
TOPB45_0207	PF01894	Uncharacterised protein family UPF0047
TOPB45_0209	PF08502	LeuA allosteric (dimerisation) domain
TOPB45_0209	PF00682	HMGL-like
TOPB45_0210	PF18152	DAHP synthase ferredoxin-like domain
TOPB45_0210	PF00793	DAHP synthetase I family
TOPB45_0214	PF02878	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
TOPB45_0214	PF02879	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
TOPB45_0214	PF00408	Phosphoglucomutase/phosphomannomutase, C-terminal domain
TOPB45_0214	PF02880	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
TOPB45_0217	PF00056	lactate/malate dehydrogenase, NAD binding domain
TOPB45_0217	PF02866	lactate/malate dehydrogenase, alpha/beta C-terminal domain
TOPB45_0218	PF01119	DNA mismatch repair protein, C-terminal domain
TOPB45_0218	PF08676	MutL C terminal dimerisation domain
TOPB45_0221	PF01040	UbiA prenyltransferase family
TOPB45_0222	PF13614	AAA domain
TOPB45_0225	PF00440	Bacterial regulatory proteins, tetR family
TOPB45_0226	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
TOPB45_0227	PF00873	AcrB/AcrD/AcrF family
TOPB45_0228	PF02321	Outer membrane efflux protein
TOPB45_0230	PF02675	S-adenosylmethionine decarboxylase 
TOPB45_0231	PF17284	Spermidine synthase tetramerisation domain
TOPB45_0234	PF05681	Fumarate hydratase (Fumerase)
TOPB45_0235	PF00933	Glycosyl hydrolase family 3 N terminal domain
TOPB45_0236	PF00266	Aminotransferase class-V
TOPB45_0237	PF17915	Reverse gyrase zinc finger
TOPB45_0237	PF01751	Toprim domain
TOPB45_0237	PF00270	DEAD/DEAH box helicase
TOPB45_0237	PF01131	DNA topoisomerase
TOPB45_0238	PF01578	Cytochrome C assembly protein
TOPB45_0239	PF00905	Penicillin binding protein transpeptidase domain
TOPB45_0239	PF00912	Transglycosylase
TOPB45_0240	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_0240	PF08448	PAS fold
TOPB45_0240	PF00563	EAL domain
TOPB45_0241	PF02080	TrkA-C domain
TOPB45_0241	PF02254	TrkA-N domain
TOPB45_0241	PF00999	Sodium/hydrogen exchanger family
TOPB45_0242	PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase
TOPB45_0242	PF01346	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
TOPB45_0243	PF02542	YgbB family
TOPB45_0244	PF08240	Alcohol dehydrogenase GroES-like domain
TOPB45_0244	PF00107	Zinc-binding dehydrogenase
TOPB45_0245	PF00436	Single-strand binding protein family
TOPB45_0246	PF01488	Shikimate / quinate 5-dehydrogenase
TOPB45_0246	PF05201	Glutamyl-tRNAGlu reductase, N-terminal domain
TOPB45_0246	PF00745	Glutamyl-tRNAGlu reductase, dimerisation domain
TOPB45_0247	PF01578	Cytochrome C assembly protein
TOPB45_0249	PF04055	Radical SAM superfamily
TOPB45_0252	PF00472	RF-1 domain
TOPB45_0252	PF03462	PCRF domain
TOPB45_0253	PF01197	Ribosomal protein L31
TOPB45_0254	PF12804	MobA-like NTP transferase domain
TOPB45_0254	PF00132	Bacterial transferase hexapeptide (six repeats)
TOPB45_0255	PF05698	Bacterial trigger factor protein (TF) C-terminus
TOPB45_0257	PF13180	PDZ domain
TOPB45_0257	PF17820	PDZ domain
TOPB45_0259	PF02565	Recombination protein O C terminal
TOPB45_0259	PF11967	Recombination protein O N terminal
TOPB45_0260	PF03641	Possible lysine decarboxylase
TOPB45_0261	PF00185	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
TOPB45_0261	PF02729	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
TOPB45_0263	PF03331	UDP-3-O-acyl N-acetylglycosamine deacetylase
TOPB45_0264	PF03734	L,D-transpeptidase catalytic domain
TOPB45_0264	PF17969	L,D-transpeptidase C-terminal domain
TOPB45_0265	PF00291	Pyridoxal-phosphate dependent enzyme
TOPB45_0268	PF02572	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP
TOPB45_0269	PF04055	Radical SAM superfamily
TOPB45_0270	PF01979	Amidohydrolase family
TOPB45_0272	PF01209	ubiE/COQ5 methyltransferase family
TOPB45_0273	PF00072	Response regulator receiver domain
TOPB45_0273	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_0275	PF16123	Hydroxyacylglutathione hydrolase C-terminus
TOPB45_0275	PF00753	Metallo-beta-lactamase superfamily
TOPB45_0276	PF01513	ATP-NAD kinase
TOPB45_0279	PF00343	Carbohydrate phosphorylase
TOPB45_0279	PF11897	Protein of unknown function (DUF3417)
TOPB45_0281	PF00534	Glycosyl transferases group 1
TOPB45_0281	PF13439	Glycosyltransferase Family 4
TOPB45_0283	PF06071	Protein of unknown function (DUF933)
TOPB45_0283	PF01926	50S ribosome-binding GTPase
TOPB45_0285	PF00156	Phosphoribosyl transferase domain
TOPB45_0286	PF01964	Radical SAM ThiC family
TOPB45_0288	PF07690	Major Facilitator Superfamily
TOPB45_0294	PF00342	Phosphoglucose isomerase
TOPB45_0295	PF00490	Delta-aminolevulinic acid dehydratase
TOPB45_0296	PF05036	Sporulation related domain
TOPB45_0296	PF03330	Lytic transglycolase
TOPB45_0297	PF14622	Ribonuclease-III-like
TOPB45_0297	PF00035	Double-stranded RNA binding motif
TOPB45_0298	PF01926	50S ribosome-binding GTPase
TOPB45_0298	PF07650	KH domain
TOPB45_0299	PF04316	Anti-sigma-28 factor, FlgM
TOPB45_0300	PF00294	pfkB family carbohydrate kinase
TOPB45_0300	PF01467	Cytidylyltransferase-like
TOPB45_0301	PF00156	Phosphoribosyl transferase domain
TOPB45_0302	PF07687	Peptidase dimerisation domain
TOPB45_0302	PF01546	Peptidase family M20/M25/M40
TOPB45_0303	PF00708	Acylphosphatase
TOPB45_0307	PF02374	Anion-transporting ATPase
TOPB45_0307	PF17886	HSP20-like domain found in ArsA
TOPB45_0308	PF01189	16S rRNA methyltransferase RsmB/F
TOPB45_0308	PF17125	N-terminal domain of 16S rRNA methyltransferase RsmF
TOPB45_0308	PF01029	NusB family
TOPB45_0309	PF17757	UvrB interaction domain
TOPB45_0309	PF00271	Helicase conserved C-terminal domain
TOPB45_0309	PF12344	Ultra-violet resistance protein B
TOPB45_0309	PF02151	UvrB/uvrC motif
TOPB45_0309	PF04851	Type III restriction enzyme, res subunit
TOPB45_0312	PF04055	Radical SAM superfamily
TOPB45_0313	PF02581	Thiamine monophosphate synthase
TOPB45_0317	PF12706	Beta-lactamase superfamily domain
TOPB45_0319	PF00072	Response regulator receiver domain
TOPB45_0319	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_0321	PF00483	Nucleotidyl transferase
TOPB45_0321	PF01050	Mannose-6-phosphate isomerase
TOPB45_0336	PF01943	Polysaccharide biosynthesis protein
TOPB45_0338	PF03275	UDP-galactopyranose mutase
TOPB45_0341	PF00535	Glycosyl transferase family 2
TOPB45_0343	PF00483	Nucleotidyl transferase
TOPB45_0346	PF13439	Glycosyltransferase Family 4
TOPB45_0346	PF00534	Glycosyl transferases group 1
TOPB45_0350	PF13439	Glycosyltransferase Family 4
TOPB45_0350	PF00534	Glycosyl transferases group 1
TOPB45_0351	PF00483	Nucleotidyl transferase
TOPB45_0352	PF15919	HicB_like antitoxin of bacterial toxin-antitoxin system
TOPB45_0354	PF00908	dTDP-4-dehydrorhamnose 3,5-epimerase
TOPB45_0355	PF16363	GDP-mannose 4,6 dehydratase
TOPB45_0356	PF04321	RmlD substrate binding domain
TOPB45_0361	PF02397	Bacterial sugar transferase
TOPB45_0362	PF07992	Pyridine nucleotide-disulphide oxidoreductase
TOPB45_0365	PF10531	SLBB domain
TOPB45_0365	PF02563	Polysaccharide biosynthesis/export protein
TOPB45_0369	PF02152	Dihydroneopterin aldolase
TOPB45_0369	PF01288	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
TOPB45_0370	PF00155	Aminotransferase class I and II
TOPB45_0371	PF01658	Myo-inositol-1-phosphate synthase
TOPB45_0372	PF00521	DNA gyrase/topoisomerase IV, subunit A
TOPB45_0372	PF03989	DNA gyrase C-terminal domain, beta-propeller
TOPB45_0374	PF00591	Glycosyl transferase family, a/b domain
TOPB45_0374	PF02885	Glycosyl transferase family, helical bundle domain
TOPB45_0374	PF00117	Glutamine amidotransferase class-I
TOPB45_0376	PF03129	Anticodon binding domain
TOPB45_0376	PF13393	Histidyl-tRNA synthetase
TOPB45_0377	PF02852	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
TOPB45_0377	PF07992	Pyridine nucleotide-disulphide oxidoreductase
TOPB45_0378	PF02421	Ferrous iron transport protein B
TOPB45_0378	PF07670	Nucleoside recognition
TOPB45_0378	PF07664	Ferrous iron transport protein B C terminus
TOPB45_0379	PF00557	Metallopeptidase family M24
TOPB45_0379	PF01321	Creatinase/Prolidase N-terminal domain
TOPB45_0380	PF00148	Nitrogenase component 1 type Oxidoreductase
TOPB45_0380	PF08369	Proto-chlorophyllide reductase 57 kD subunit
TOPB45_0383	PF01814	Hemerythrin HHE cation binding domain
TOPB45_0383	PF04405	Domain of Unknown function (DUF542)  
TOPB45_0387	PF04551	GcpE protein
TOPB45_0388	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
TOPB45_0389	PF00593	TonB dependent receptor
TOPB45_0389	PF07715	TonB-dependent Receptor Plug Domain
TOPB45_0392	PF07992	Pyridine nucleotide-disulphide oxidoreductase
TOPB45_0393	PF03599	CO dehydrogenase/acetyl-CoA synthase delta subunit
TOPB45_0393	PF04060	Putative Fe-S cluster
TOPB45_0394	PF03598	CO dehydrogenase/acetyl-CoA synthase complex beta subunit
TOPB45_0394	PF18537	Carbon monoxide dehydrogenase subunit alpha N-terminal domain
TOPB45_0395	PF03599	CO dehydrogenase/acetyl-CoA synthase delta subunit
TOPB45_0396	PF02574	Homocysteine S-methyltransferase
TOPB45_0396	PF02219	Methylenetetrahydrofolate reductase
TOPB45_0398	PF03063	Prismane/CO dehydrogenase family
TOPB45_0399	PF00763	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
TOPB45_0399	PF02882	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
TOPB45_0400	PF01268	Formate--tetrahydrofolate ligase
TOPB45_0401	PF01370	NAD dependent epimerase/dehydratase family
TOPB45_0402	PF02272	DHHA1 domain
TOPB45_0402	PF01368	DHH family
TOPB45_0402	PF10141	Single-strand DNA-specific exonuclease, C terminal domain
TOPB45_0402	PF17768	RecJ OB domain
TOPB45_0403	PF13286	Phosphohydrolase-associated domain
TOPB45_0403	PF01966	HD domain
TOPB45_0406	PF00582	Universal stress protein family
TOPB45_0407	PF00857	Isochorismatase family
TOPB45_0408	PF17956	Nicotinate phosphoribosyltransferase C-terminal domain
TOPB45_0408	PF17767	Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain
TOPB45_0408	PF04095	Nicotinate phosphoribosyltransferase (NAPRTase) family
TOPB45_0409	PF00675	Insulinase (Peptidase family M16)
TOPB45_0409	PF05193	Peptidase M16 inactive domain
TOPB45_0410	PF02367	Threonylcarbamoyl adenosine biosynthesis protein TsaE
TOPB45_0411	PF02685	Glucokinase
TOPB45_0413	PF00691	OmpA family
TOPB45_0416	PF00448	SRP54-type protein, GTPase domain
TOPB45_0416	PF02881	SRP54-type protein, helical bundle domain
TOPB45_0418	PF00708	Acylphosphatase
TOPB45_0418	PF07503	HypF finger
TOPB45_0418	PF01300	Telomere recombination
TOPB45_0418	PF17788	HypF Kae1-like domain
TOPB45_0419	PF00149	Calcineurin-like phosphoesterase
TOPB45_0420	PF01557	Fumarylacetoacetate (FAA) hydrolase family
TOPB45_0421	PF06463	Molybdenum Cofactor Synthesis C
TOPB45_0421	PF04055	Radical SAM superfamily
TOPB45_0422	PF02441	Flavoprotein
TOPB45_0422	PF04127	DNA / pantothenate metabolism flavoprotein
TOPB45_0424	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_0424	PF17158	Membrane-associated sensor, integral membrane domain
TOPB45_0425	PF00171	Aldehyde dehydrogenase family
TOPB45_0426	PF01467	Cytidylyltransferase-like
TOPB45_0428	PF11741	AMIN domain
TOPB45_0428	PF01520	N-acetylmuramoyl-L-alanine amidase
TOPB45_0429	PF07075	Protein of unknown function (DUF1343)
TOPB45_0431	PF01018	GTP1/OBG
TOPB45_0431	PF01926	50S ribosome-binding GTPase
TOPB45_0432	PF01472	PUA domain
TOPB45_0432	PF00696	Amino acid kinase family
TOPB45_0433	PF07733	Bacterial DNA polymerase III alpha NTPase domain
TOPB45_0433	PF02811	PHP domain
TOPB45_0433	PF14579	Helix-hairpin-helix motif
TOPB45_0433	PF17657	Bacterial DNA polymerase III alpha subunit finger domain
TOPB45_0435	PF03968	OstA-like protein
TOPB45_0435	PF04453	LPS transport system D
TOPB45_0436	PF02590	Predicted SPOUT methyltransferase
TOPB45_0437	PF00850	Histone deacetylase domain
TOPB45_0438	PF13533	Biotin-lipoyl like
TOPB45_0439	PF00005	ABC transporter
TOPB45_0440	PF00005	ABC transporter
TOPB45_0445	PF01435	Peptidase family M48
TOPB45_0445	PF07720	Tetratricopeptide repeat
TOPB45_0449	PF00291	Pyridoxal-phosphate dependent enzyme
TOPB45_0450	PF00290	Tryptophan synthase alpha chain
TOPB45_0451	PF01761	3-dehydroquinate synthase
TOPB45_0452	PF01678	Diaminopimelate epimerase
TOPB45_0453	PF00701	Dihydrodipicolinate synthetase family
TOPB45_0454	PF00465	Iron-containing alcohol dehydrogenase 
TOPB45_0458	PF00486	Transcriptional regulatory protein, C terminal
TOPB45_0458	PF00072	Response regulator receiver domain
TOPB45_0459	PF00512	His Kinase A (phospho-acceptor) domain
TOPB45_0459	PF00672	HAMP domain
TOPB45_0459	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
TOPB45_0459	PF18698	Histidine kinase sensor domain
TOPB45_0459	PF00989	PAS fold
TOPB45_0460	PF03707	Bacterial signalling protein N terminal repeat
TOPB45_0460	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_0460	PF00563	EAL domain
TOPB45_0461	PF02649	Type I GTP cyclohydrolase folE2
TOPB45_0463	PF02492	CobW/HypB/UreG, nucleotide-binding domain
TOPB45_0464	PF00586	AIR synthase related protein, N-terminal domain
TOPB45_0464	PF02769	AIR synthase related protein, C-terminal domain
TOPB45_0465	PF01155	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
TOPB45_0466	PF01750	Hydrogenase maturation protease
TOPB45_0467	PF00582	Universal stress protein family
TOPB45_0470	PF03099	Biotin/lipoate A/B protein ligase family
TOPB45_0470	PF08279	HTH domain
TOPB45_0470	PF02237	Biotin protein ligase C terminal domain
TOPB45_0471	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_0472	PF14437	MafB19-like deaminase
TOPB45_0473	PF02401	LytB protein
TOPB45_0474	PF04002	RadC-like JAB domain
TOPB45_0477	PF00793	DAHP synthetase I family
TOPB45_0482	PF00534	Glycosyl transferases group 1
TOPB45_0484	PF00982	Glycosyltransferase family 20
TOPB45_0486	PF00764	Arginosuccinate synthase
TOPB45_0487	PF00923	Transaldolase/Fructose-6-phosphate aldolase
TOPB45_0488	PF01569	PAP2 superfamily
TOPB45_0490	PF18073	Rubredoxin metal binding domain
TOPB45_0494	PF02146	Sir2 family
TOPB45_0495	PF03091	CutA1 divalent ion tolerance protein
TOPB45_0496	PF00994	Probable molybdopterin binding domain
TOPB45_0496	PF03454	MoeA C-terminal region (domain IV)
TOPB45_0496	PF03453	MoeA N-terminal region (domain I and II)
TOPB45_0498	PF13247	4Fe-4S dicluster domain
TOPB45_0500	PF12728	Helix-turn-helix domain
TOPB45_0500	PF12727	PBP superfamily domain
TOPB45_0501	PF03631	Virulence factor BrkB
TOPB45_0503	PF01063	Amino-transferase class IV
TOPB45_0506	PF04055	Radical SAM superfamily
TOPB45_0507	PF18674	TarS beta-glycosyltransferase C-terminal domain 1
TOPB45_0507	PF00535	Glycosyl transferase family 2
TOPB45_0510	PF00534	Glycosyl transferases group 1
TOPB45_0510	PF13439	Glycosyltransferase Family 4
TOPB45_0512	PF00534	Glycosyl transferases group 1
TOPB45_0512	PF13439	Glycosyltransferase Family 4
TOPB45_0515	PF11146	Protein of unknown function (DUF2905)
TOPB45_0517	PF04055	Radical SAM superfamily
TOPB45_0517	PF00919	Uncharacterized protein family UPF0004
TOPB45_0518	PF01066	CDP-alcohol phosphatidyltransferase
TOPB45_0519	PF02677	Epoxyqueuosine reductase QueH
TOPB45_0522	PF01475	Ferric uptake regulator family
TOPB45_0524	PF00156	Phosphoribosyl transferase domain
TOPB45_0525	PF12849	PBP superfamily domain
TOPB45_0526	PF00528	Binding-protein-dependent transport system inner membrane component
TOPB45_0527	PF00528	Binding-protein-dependent transport system inner membrane component
TOPB45_0528	PF00005	ABC transporter
TOPB45_0529	PF01960	ArgJ family
TOPB45_0530	PF01975	Survival protein SurE
TOPB45_0532	PF01687	Riboflavin kinase
TOPB45_0532	PF06574	FAD synthetase
TOPB45_0533	PF00117	Glutamine amidotransferase class-I
TOPB45_0533	PF00988	Carbamoyl-phosphate synthase small chain, CPSase domain
TOPB45_0536	PF00258	Flavodoxin
TOPB45_0536	PF00753	Metallo-beta-lactamase superfamily
TOPB45_0538	PF00301	Rubredoxin
TOPB45_0539	PF00301	Rubredoxin
TOPB45_0540	PF00301	Rubredoxin
TOPB45_0541	PF01880	Desulfoferrodoxin
TOPB45_0541	PF06397	Desulfoferrodoxin, N-terminal domain
TOPB45_0543	PF00216	Bacterial DNA-binding protein
TOPB45_0544	PF03147	Ferredoxin-fold anticodon binding domain
TOPB45_0544	PF01588	Putative tRNA binding domain
TOPB45_0544	PF17759	Phenylalanyl tRNA synthetase beta chain CLM domain
TOPB45_0544	PF03484	tRNA synthetase B5 domain
TOPB45_0544	PF03483	B3/4 domain
TOPB45_0545	PF02912	Aminoacyl tRNA synthetase class II, N-terminal domain
TOPB45_0545	PF01409	tRNA synthetases class II core domain (F)
TOPB45_0546	PF00453	Ribosomal protein L20
TOPB45_0547	PF01632	Ribosomal protein L35
TOPB45_0548	PF02548	Ketopantoate hydroxymethyltransferase
TOPB45_0549	PF05491	RuvB C-terminal winged helix domain
TOPB45_0549	PF17864	RuvB AAA lid domain
TOPB45_0549	PF05496	Holliday junction DNA helicase RuvB P-loop domain
TOPB45_0550	PF00672	HAMP domain
TOPB45_0550	PF00015	Methyl-accepting chemotaxis protein (MCP) signalling domain
TOPB45_0550	PF12729	Four helix bundle sensory module for signal transduction
TOPB45_0554	PF01926	50S ribosome-binding GTPase
TOPB45_0556	PF00578	AhpC/TSA family
TOPB45_0556	PF10417	C-terminal domain of 1-Cys peroxiredoxin
TOPB45_0558	PF00294	pfkB family carbohydrate kinase
TOPB45_0559	PF01523	Putative modulator of DNA gyrase
TOPB45_0560	PF00156	Phosphoribosyl transferase domain
TOPB45_0561	PF01977	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TOPB45_0563	PF04073	Aminoacyl-tRNA editing domain
TOPB45_0563	PF00587	tRNA synthetase class II core domain (G, H, P, S and T)
TOPB45_0563	PF03129	Anticodon binding domain
TOPB45_0564	PF04613	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD  
TOPB45_0564	PF00132	Bacterial transferase hexapeptide (six repeats)
TOPB45_0567	PF00350	Dynamin family
TOPB45_0569	PF01814	Hemerythrin HHE cation binding domain
TOPB45_0574	PF07690	Major Facilitator Superfamily
TOPB45_0576	PF07499	RuvA, C-terminal domain
TOPB45_0576	PF01330	RuvA N terminal domain
TOPB45_0577	PF02075	Crossover junction endodeoxyribonuclease RuvC
TOPB45_0578	PF01709	Transcriptional regulator
TOPB45_0580	PF03446	NAD binding domain of 6-phosphogluconate dehydrogenase
TOPB45_0580	PF14833	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
TOPB45_0584	PF08029	HisG, C-terminal domain
TOPB45_0584	PF01634	ATP phosphoribosyltransferase
TOPB45_0585	PF01502	Phosphoribosyl-AMP cyclohydrolase
TOPB45_0586	PF00218	Indole-3-glycerol phosphate synthase
TOPB45_0587	PF00468	Ribosomal protein L34
TOPB45_0588	PF00825	Ribonuclease P
TOPB45_0589	PF01809	Putative membrane protein insertion efficiency factor
TOPB45_0590	PF02096	60Kd inner membrane protein
TOPB45_0590	PF14849	YidC periplasmic domain
TOPB45_0592	PF12631	MnmE helical domain
TOPB45_0592	PF10396	GTP-binding protein TrmE N-terminus
TOPB45_0592	PF01926	50S ribosome-binding GTPase
TOPB45_0593	PF01968	Hydantoinase/oxoprolinase
TOPB45_0593	PF05378	Hydantoinase/oxoprolinase N-terminal region
TOPB45_0595	PF08543	Phosphomethylpyrimidine kinase
TOPB45_0596	PF02686	Glu-tRNAGln amidotransferase C subunit
TOPB45_0597	PF01425	Amidase
TOPB45_0598	PF02195	ParB-like nuclease domain
TOPB45_0598	PF17762	HTH domain found in ParB protein
TOPB45_0599	PF00862	Sucrose synthase
TOPB45_0599	PF00534	Glycosyl transferases group 1
TOPB45_0602	PF01210	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
TOPB45_0602	PF07479	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
TOPB45_0603	PF00496	Bacterial extracellular solute-binding proteins, family 5 Middle
TOPB45_0605	PF02834	LigT like Phosphoesterase
TOPB45_0606	PF00994	Probable molybdopterin binding domain
TOPB45_0606	PF02464	Competence-damaged protein
TOPB45_0606	PF18146	Damage-inducible protein CinA KH domain
TOPB45_0607	PF04608	Phosphatidylglycerophosphatase A
TOPB45_0609	PF01370	NAD dependent epimerase/dehydratase family
TOPB45_0609	PF08338	Domain of unknown function (DUF1731)
TOPB45_0610	PF07885	Ion channel
TOPB45_0610	PF02254	TrkA-N domain
TOPB45_0611	PF00582	Universal stress protein family
TOPB45_0612	PF03600	Citrate transporter
TOPB45_0613	PF00535	Glycosyl transferase family 2
TOPB45_0614	PF17191	RecG wedge domain
TOPB45_0614	PF00270	DEAD/DEAH box helicase
TOPB45_0614	PF00271	Helicase conserved C-terminal domain
TOPB45_0616	PF01790	Prolipoprotein diacylglyceryl transferase
TOPB45_0617	PF00633	Helix-hairpin-helix motif
TOPB45_0617	PF00730	HhH-GPD superfamily base excision DNA repair protein
TOPB45_0619	PF07973	Threonyl and Alanyl tRNA synthetase second additional domain
TOPB45_0619	PF01411	tRNA synthetases class II (A)
TOPB45_0619	PF02272	DHHA1 domain
TOPB45_0620	PF00438	S-adenosylmethionine synthetase, N-terminal domain
TOPB45_0620	PF02772	S-adenosylmethionine synthetase, central domain
TOPB45_0620	PF02773	S-adenosylmethionine synthetase, C-terminal domain
TOPB45_0621	PF05221	S-adenosyl-L-homocysteine hydrolase
TOPB45_0621	PF00670	S-adenosyl-L-homocysteine hydrolase, NAD binding domain
TOPB45_0622	PF00677	Lumazine binding domain
TOPB45_0624	PF03807	NADP oxidoreductase coenzyme F420-dependent
TOPB45_0624	PF14748	Pyrroline-5-carboxylate reductase dimerisation
TOPB45_0625	PF01384	Phosphate transporter family
TOPB45_0628	PF00459	Inositol monophosphatase family
TOPB45_0629	PF00072	Response regulator receiver domain
TOPB45_0629	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_0630	PF00575	S1 RNA binding domain
TOPB45_0630	PF00773	RNB domain
TOPB45_0631	PF00977	Histidine biosynthesis protein
TOPB45_0633	PF13607	Succinyl-CoA ligase like flavodoxin domain
TOPB45_0633	PF00583	Acetyltransferase (GNAT) family
TOPB45_0633	PF13380	CoA binding domain
TOPB45_0635	PF01979	Amidohydrolase family
TOPB45_0636	PF00501	AMP-binding enzyme
TOPB45_0636	PF13193	AMP-binding enzyme C-terminal domain
TOPB45_0636	PF16177	Acetyl-coenzyme A synthetase N-terminus
TOPB45_0637	PF00465	Iron-containing alcohol dehydrogenase 
TOPB45_0638	PF00389	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
TOPB45_0638	PF02826	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
TOPB45_0639	PF01872	RibD C-terminal domain
TOPB45_0642	PF00440	Bacterial regulatory proteins, tetR family
TOPB45_0645	PF00501	AMP-binding enzyme
TOPB45_0645	PF14535	AMP-binding enzyme C-terminal domain
TOPB45_0647	PF14535	AMP-binding enzyme C-terminal domain
TOPB45_0647	PF00501	AMP-binding enzyme
TOPB45_0649	PF02652	L-lactate permease
TOPB45_0654	PF02618	YceG-like family
TOPB45_0655	PF00398	Ribosomal RNA adenine dimethylase
TOPB45_0656	PF18693	TRAM domain
TOPB45_0656	PF04055	Radical SAM superfamily
TOPB45_0656	PF00919	Uncharacterized protein family UPF0004
TOPB45_0657	PF00083	Sugar (and other) transporter
TOPB45_0660	PF16363	GDP-mannose 4,6 dehydratase
TOPB45_0662	PF00202	Aminotransferase class-III
TOPB45_0663	PF01450	Acetohydroxy acid isomeroreductase, catalytic domain
TOPB45_0663	PF07991	Acetohydroxy acid isomeroreductase, NADPH-binding domain
TOPB45_0665	PF00158	Sigma-54 interaction domain
TOPB45_0665	PF00072	Response regulator receiver domain
TOPB45_0665	PF02954	Bacterial regulatory protein, Fis family
TOPB45_0666	PF13426	PAS domain
TOPB45_0666	PF13188	PAS domain
TOPB45_0666	PF00989	PAS fold
TOPB45_0666	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
TOPB45_0666	PF00512	His Kinase A (phospho-acceptor) domain
TOPB45_0667	PF01569	PAP2 superfamily
TOPB45_0669	PF02580	D-Tyr-tRNA(Tyr) deacylase
TOPB45_0674	PF00698	Acyl transferase domain
TOPB45_0675	PF01597	Glycine cleavage H-protein
TOPB45_0676	PF01312	FlhB HrpN YscU SpaS Family
TOPB45_0677	PF01950	Fructose-1,6-bisphosphatase
TOPB45_0679	PF02472	Biopolymer transport protein ExbD/TolR
TOPB45_0684	PF03548	Outer membrane lipoprotein carrier protein LolA
TOPB45_0685	PF17854	FtsK alpha domain
TOPB45_0685	PF13491	4TM region of DNA translocase FtsK/SpoIIIE
TOPB45_0685	PF01580	FtsK/SpoIIIE family
TOPB45_0685	PF09397	Ftsk gamma domain
TOPB45_0687	PF03797	Autotransporter beta-domain
TOPB45_0688	PF03129	Anticodon binding domain
TOPB45_0688	PF00587	tRNA synthetase class II core domain (G, H, P, S and T)
TOPB45_0688	PF07973	Threonyl and Alanyl tRNA synthetase second additional domain
TOPB45_0689	PF05198	Translation initiation factor IF-3, N-terminal domain
TOPB45_0689	PF00707	Translation initiation factor IF-3, C-terminal domain
TOPB45_0690	PF00117	Glutamine amidotransferase class-I
TOPB45_0692	PF04079	Segregation and condensation complex subunit ScpB
TOPB45_0693	PF01018	GTP1/OBG
TOPB45_0693	PF01926	50S ribosome-binding GTPase
TOPB45_0693	PF04055	Radical SAM superfamily
TOPB45_0694	PF01066	CDP-alcohol phosphatidyltransferase
TOPB45_0695	PF00834	Ribulose-phosphate 3 epimerase family
TOPB45_0697	PF00278	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
TOPB45_0697	PF02784	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
TOPB45_0698	PF02547	Queuosine biosynthesis protein
TOPB45_0699	PF07690	Major Facilitator Superfamily
TOPB45_0701	PF03372	Endonuclease/Exonuclease/phosphatase family
TOPB45_0704	PF03477	ATP cone domain
TOPB45_0704	PF02867	Ribonucleotide reductase, barrel domain
TOPB45_0704	PF00317	Ribonucleotide reductase, all-alpha domain
TOPB45_0705	PF02978	Signal peptide binding domain
TOPB45_0705	PF00448	SRP54-type protein, GTPase domain
TOPB45_0705	PF02881	SRP54-type protein, helical bundle domain
TOPB45_0708	PF01782	RimM N-terminal domain
TOPB45_0708	PF05239	PRC-barrel domain
TOPB45_0709	PF01746	tRNA (Guanine-1)-methyltransferase
TOPB45_0709	PF09936	SAM-dependent RNA methyltransferase
TOPB45_0710	PF00403	Heavy-metal-associated domain
TOPB45_0711	PF00403	Heavy-metal-associated domain
TOPB45_0712	PF02786	Carbamoyl-phosphate synthase L chain, ATP binding domain
TOPB45_0712	PF02785	Biotin carboxylase C-terminal domain
TOPB45_0712	PF00289	Biotin carboxylase, N-terminal domain
TOPB45_0713	PF00364	Biotin-requiring enzyme
TOPB45_0715	PF00572	Ribosomal protein L13
TOPB45_0716	PF00380	Ribosomal protein S9/S16
TOPB45_0717	PF01118	Semialdehyde dehydrogenase, NAD binding domain
TOPB45_0717	PF02774	Semialdehyde dehydrogenase, dimerisation domain
TOPB45_0718	PF01416	tRNA pseudouridine synthase
TOPB45_0719	PF00475	Imidazoleglycerol-phosphate dehydratase
TOPB45_0721	PF01406	tRNA synthetases class I (C) catalytic domain
TOPB45_0721	PF09190	DALR domain
TOPB45_0722	PF01656	CobQ/CobB/MinD/ParA nucleotide binding domain
TOPB45_0723	PF08502	LeuA allosteric (dimerisation) domain
TOPB45_0723	PF00682	HMGL-like
TOPB45_0724	PF01842	ACT domain
TOPB45_0724	PF13840	ACT domain 
TOPB45_0724	PF00696	Amino acid kinase family
TOPB45_0728	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
TOPB45_0729	PF13520	Amino acid permease
TOPB45_0734	PF00005	ABC transporter
TOPB45_0736	PF01871	AMMECR1
TOPB45_0738	PF00881	Nitroreductase family
TOPB45_0740	PF17284	Spermidine synthase tetramerisation domain
TOPB45_0741	PF00226	DnaJ domain
TOPB45_0741	PF01556	DnaJ C terminal domain
TOPB45_0742	PF00383	Cytidine and deoxycytidylate deaminase zinc-binding region
TOPB45_0743	PF00464	Serine hydroxymethyltransferase
TOPB45_0744	PF00535	Glycosyl transferase family 2
TOPB45_0748	PF00164	Ribosomal protein S12/S23
TOPB45_0749	PF00177	Ribosomal protein S7p/S5e
TOPB45_0750	PF00009	Elongation factor Tu GTP binding domain
TOPB45_0750	PF03764	Elongation factor G, domain IV
TOPB45_0750	PF00679	Elongation factor G C-terminus
TOPB45_0750	PF03144	Elongation factor Tu domain 2
TOPB45_0750	PF14492	Elongation Factor G, domain II
TOPB45_0751	PF03143	Elongation factor Tu C-terminal domain
TOPB45_0751	PF03144	Elongation factor Tu domain 2
TOPB45_0751	PF00009	Elongation factor Tu GTP binding domain
TOPB45_0752	PF00338	Ribosomal protein S10p/S20e
TOPB45_0753	PF00297	Ribosomal protein L3
TOPB45_0754	PF00573	Ribosomal protein L4/L1 family
TOPB45_0755	PF00276	Ribosomal protein L23
TOPB45_0756	PF00181	Ribosomal Proteins L2, RNA binding domain
TOPB45_0756	PF03947	Ribosomal Proteins L2, C-terminal domain
TOPB45_0757	PF00203	Ribosomal protein S19
TOPB45_0758	PF00237	Ribosomal protein L22p/L17e
TOPB45_0759	PF07650	KH domain
TOPB45_0759	PF00189	Ribosomal protein S3, C-terminal domain
TOPB45_0760	PF00252	Ribosomal protein L16p/L10e
TOPB45_0761	PF00831	Ribosomal L29 protein
TOPB45_0762	PF00366	Ribosomal protein S17
TOPB45_0763	PF00238	Ribosomal protein L14p/L23e
TOPB45_0764	PF17136	Ribosomal proteins 50S L24/mitochondrial 39S L24
TOPB45_0764	PF00467	KOW motif
TOPB45_0765	PF00673	ribosomal L5P family C-terminus
TOPB45_0765	PF00281	Ribosomal protein L5
TOPB45_0766	PF00253	Ribosomal protein S14p/S29e
TOPB45_0767	PF00410	Ribosomal protein S8
TOPB45_0768	PF00347	Ribosomal protein L6
TOPB45_0769	PF00861	Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
TOPB45_0770	PF00333	Ribosomal protein S5, N-terminal domain
TOPB45_0770	PF03719	Ribosomal protein S5, C-terminal domain
TOPB45_0771	PF00327	Ribosomal protein L30p/L7e
TOPB45_0772	PF00828	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
TOPB45_0773	PF00344	SecY translocase
TOPB45_0774	PF05191	Adenylate kinase, active site lid
TOPB45_0775	PF00557	Metallopeptidase family M24
TOPB45_0776	PF01176	Translation initiation factor 1A / IF-1
TOPB45_0777	PF00444	Ribosomal protein L36
TOPB45_0778	PF00416	Ribosomal protein S13/S18
TOPB45_0779	PF00411	Ribosomal protein S11
TOPB45_0780	PF01479	S4 domain
TOPB45_0780	PF00163	Ribosomal protein S4/S9 N-terminal domain
TOPB45_0781	PF01000	RNA polymerase Rpb3/RpoA insert domain
TOPB45_0781	PF03118	Bacterial RNA polymerase, alpha chain C terminal domain
TOPB45_0781	PF01193	RNA polymerase Rpb3/Rpb11 dimerisation domain
TOPB45_0782	PF01196	Ribosomal protein L17
TOPB45_0783	PF01966	HD domain
TOPB45_0783	PF01743	Poly A polymerase head domain
TOPB45_0783	PF12627	Probable RNA and SrmB- binding site of polymerase A
TOPB45_0784	PF05698	Bacterial trigger factor protein (TF) C-terminus
TOPB45_0784	PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase
TOPB45_0784	PF05697	Bacterial trigger factor protein (TF)
TOPB45_0785	PF00574	Clp protease
TOPB45_0786	PF06689	ClpX C4-type zinc finger
TOPB45_0786	PF10431	C-terminal, D2-small domain, of ClpB protein 
TOPB45_0786	PF07724	AAA domain (Cdc48 subfamily)
TOPB45_0787	PF02190	ATP-dependent protease La (LON) substrate-binding domain 
TOPB45_0787	PF05362	Lon protease (S16) C-terminal proteolytic domain
TOPB45_0787	PF00004	ATPase family associated with various cellular activities (AAA)
TOPB45_0788	PF07497	Rho termination factor, RNA-binding domain
TOPB45_0788	PF07498	Rho termination factor, N-terminal domain
TOPB45_0788	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain
TOPB45_0789	PF17805	AsnC-like ligand binding domain
TOPB45_0790	PF13231	Dolichyl-phosphate-mannose-protein mannosyltransferase
TOPB45_0792	PF00672	HAMP domain
TOPB45_0792	PF00512	His Kinase A (phospho-acceptor) domain
TOPB45_0792	PF00989	PAS fold
TOPB45_0792	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
TOPB45_0793	PF01367	5'-3' exonuclease, C-terminal SAM fold
TOPB45_0793	PF02739	5'-3' exonuclease, N-terminal resolvase-like domain
TOPB45_0793	PF00476	DNA polymerase family A
TOPB45_0794	PF01165	Ribosomal protein S21
TOPB45_0795	PF01713	Smr domain
TOPB45_0795	PF00488	MutS domain V
TOPB45_0796	PF01807	CHC2 zinc finger
TOPB45_0796	PF10410	DnaB-helicase binding domain of primase
TOPB45_0796	PF08275	DNA primase catalytic core, N-terminal domain
TOPB45_0797	PF04545	Sigma-70, region 4
TOPB45_0797	PF04539	Sigma-70 region 3
TOPB45_0797	PF04542	Sigma-70 region 2 
TOPB45_0797	PF00140	Sigma-70 factor, region 1.2
TOPB45_0797	PF03979	Sigma-70 factor, region 1.1
TOPB45_0797	PF04546	Sigma-70, non-essential region
TOPB45_0799	PF01925	Sulfite exporter TauE/SafE
TOPB45_0800	PF01435	Peptidase family M48
TOPB45_0817	PF17820	PDZ domain
TOPB45_0817	PF13180	PDZ domain
TOPB45_0821	PF02698	DUF218 domain
TOPB45_0822	PF13580	SIS domain
TOPB45_0823	PF00814	Glycoprotease family
TOPB45_0824	PF00158	Sigma-54 interaction domain
TOPB45_0824	PF02954	Bacterial regulatory protein, Fis family
TOPB45_0824	PF00072	Response regulator receiver domain
TOPB45_0825	PF02632	BioY family
TOPB45_0826	PF02675	S-adenosylmethionine decarboxylase 
TOPB45_0827	PF00491	Arginase family
TOPB45_0831	PF00149	Calcineurin-like phosphoesterase
TOPB45_0833	PF00589	Phage integrase family
TOPB45_0833	PF02899	Phage integrase, N-terminal SAM-like domain
TOPB45_0834	PF01743	Poly A polymerase head domain
TOPB45_0834	PF12627	Probable RNA and SrmB- binding site of polymerase A
TOPB45_0834	PF13735	tRNA nucleotidyltransferase domain 2 putative
TOPB45_0835	PF00575	S1 RNA binding domain
TOPB45_0836	PF01343	Peptidase family S49
TOPB45_0837	PF00216	Bacterial DNA-binding protein
TOPB45_0838	PF00478	IMP dehydrogenase / GMP reductase domain
TOPB45_0838	PF00571	CBS domain
TOPB45_0839	PF00482	Type II secretion system (T2SS), protein F
TOPB45_0841	PF02673	Bacitracin resistance protein BacA
TOPB45_0843	PF17827	PrmC N-terminal domain
TOPB45_0843	PF05175	Methyltransferase small domain
TOPB45_0844	PF00275	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
TOPB45_0845	PF09115	DNA polymerase III, delta subunit, C terminal
TOPB45_0850	PF10143	2,3-bisphosphoglycerate-independent phosphoglycerate mutase
TOPB45_0850	PF01676	Metalloenzyme superfamily
TOPB45_0851	PF01618	MotA/TolQ/ExbB proton channel family
TOPB45_0852	PF02472	Biopolymer transport protein ExbD/TolR
TOPB45_0857	PF00912	Transglycosylase
TOPB45_0859	PF01068	ATP dependent DNA ligase domain
TOPB45_0859	PF04679	ATP dependent DNA ligase C terminal region        
TOPB45_0859	PF04675	DNA ligase N terminus
TOPB45_0869	PF07726	ATPase family associated with various cellular activities (AAA)
TOPB45_0869	PF17863	AAA lid domain
TOPB45_0872	PF02163	Peptidase family M50
TOPB45_0872	PF17820	PDZ domain
TOPB45_0874	PF00588	SpoU rRNA Methylase family
TOPB45_0875	PF05958	tRNA (Uracil-5-)-methyltransferase
TOPB45_0876	PF01869	BadF/BadG/BcrA/BcrD ATPase family
TOPB45_0879	PF00119	ATP synthase A chain
TOPB45_0880	PF00137	ATP synthase subunit C
TOPB45_0881	PF01078	Magnesium chelatase, subunit ChlI
TOPB45_0881	PF13335	Magnesium chelatase, subunit ChlI C-terminal
TOPB45_0882	PF01066	CDP-alcohol phosphatidyltransferase
TOPB45_0882	PF00483	Nucleotidyl transferase
TOPB45_0883	PF01455	HupF/HypC family
TOPB45_0884	PF01924	Hydrogenase formation hypA family
TOPB45_0885	PF00374	Nickel-dependent hydrogenase
TOPB45_0886	PF01058	NADH ubiquinone oxidoreductase, 20 Kd subunit
TOPB45_0886	PF14720	NiFe/NiFeSe hydrogenase small subunit C-terminal
TOPB45_0888	PF01022	Bacterial regulatory protein, arsR family
TOPB45_0894	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
TOPB45_0894	PF00512	His Kinase A (phospho-acceptor) domain
TOPB45_0894	PF00989	PAS fold
TOPB45_0895	PF00158	Sigma-54 interaction domain
TOPB45_0895	PF02954	Bacterial regulatory protein, Fis family
TOPB45_0895	PF00072	Response regulator receiver domain
TOPB45_0896	PF13247	4Fe-4S dicluster domain
TOPB45_0896	PF12800	4Fe-4S binding domain
TOPB45_0897	PF01568	Molydopterin dinucleotide binding domain
TOPB45_0897	PF00384	Molybdopterin oxidoreductase
TOPB45_0897	PF04879	Molybdopterin oxidoreductase Fe4S4 domain
TOPB45_0902	PF06827	Zinc finger found in FPG and IleRS
TOPB45_0902	PF00133	tRNA synthetases class I (I, L, M and V)
TOPB45_0902	PF08264	Anticodon-binding domain of tRNA
TOPB45_0903	PF01252	Signal peptidase (SPase) II
TOPB45_0906	PF00180	Isocitrate/isopropylmalate dehydrogenase
TOPB45_0907	PF01541	GIY-YIG catalytic domain
TOPB45_0907	PF02151	UvrB/uvrC motif
TOPB45_0907	PF08459	UvrC Helix-hairpin-helix N-terminal
TOPB45_0908	PF00196	Bacterial regulatory proteins, luxR family
TOPB45_0908	PF00072	Response regulator receiver domain
TOPB45_0914	PF03783	Curli production assembly/transport component CsgG
TOPB45_0916	PF00437	Type II/IV secretion system protein
TOPB45_0917	PF00482	Type II secretion system (T2SS), protein F
TOPB45_0919	PF13401	AAA domain
TOPB45_0919	PF01471	Putative peptidoglycan binding domain
TOPB45_0926	PF00114	Pilin (bacterial filament)
TOPB45_0926	PF07963	Prokaryotic N-terminal methylation motif
TOPB45_0927	PF02875	Mur ligase family, glutamate ligase domain
TOPB45_0927	PF01225	Mur ligase family, catalytic domain
TOPB45_0927	PF08245	Mur ligase middle domain
TOPB45_0930	PF13476	AAA domain
TOPB45_0931	PF00005	ABC transporter
TOPB45_0931	PF08402	TOBE domain
TOPB45_0932	PF00528	Binding-protein-dependent transport system inner membrane component
TOPB45_0935	PF02381	MraZ protein, putative antitoxin-like
TOPB45_0936	PF01795	MraW methylase family
TOPB45_0939	PF08245	Mur ligase middle domain
TOPB45_0939	PF02875	Mur ligase family, glutamate ligase domain
TOPB45_0939	PF01225	Mur ligase family, catalytic domain
TOPB45_0940	PF01225	Mur ligase family, catalytic domain
TOPB45_0940	PF02875	Mur ligase family, glutamate ligase domain
TOPB45_0940	PF08245	Mur ligase middle domain
TOPB45_0942	PF08245	Mur ligase middle domain
TOPB45_0942	PF02875	Mur ligase family, glutamate ligase domain
TOPB45_0943	PF04101	Glycosyltransferase family 28 C-terminal domain
TOPB45_0943	PF03033	Glycosyltransferase family 28 N-terminal domain
TOPB45_0944	PF08245	Mur ligase middle domain
TOPB45_0944	PF01225	Mur ligase family, catalytic domain
TOPB45_0944	PF02875	Mur ligase family, glutamate ligase domain
TOPB45_0945	PF02873	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
TOPB45_0945	PF01565	FAD binding domain 
TOPB45_0947	PF02491	SHS2 domain inserted in FTSA
TOPB45_0948	PF12327	FtsZ family, C-terminal domain
TOPB45_0948	PF00091	Tubulin/FtsZ family, GTPase domain
TOPB45_0951	PF00697	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
TOPB45_0955	PF01430	Hsp33 protein
TOPB45_0956	PF01180	Dihydroorotate dehydrogenase
TOPB45_0957	PF10418	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
TOPB45_0959	PF03023	Lipid II flippase MurJ
TOPB45_0960	PF00926	3,4-dihydroxy-2-butanone 4-phosphate synthase
TOPB45_0960	PF00925	GTP cyclohydrolase II
TOPB45_0962	PF00535	Glycosyl transferase family 2
TOPB45_0969	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
TOPB45_0969	PF00989	PAS fold
TOPB45_0969	PF13188	PAS domain
TOPB45_0969	PF00512	His Kinase A (phospho-acceptor) domain
TOPB45_0969	PF13426	PAS domain
TOPB45_0970	PF02954	Bacterial regulatory protein, Fis family
TOPB45_0970	PF00072	Response regulator receiver domain
TOPB45_0970	PF00158	Sigma-54 interaction domain
TOPB45_0973	PF01938	TRAM domain
TOPB45_0973	PF04055	Radical SAM superfamily
TOPB45_0973	PF00919	Uncharacterized protein family UPF0004
TOPB45_0974	PF02633	Creatinine amidohydrolase
TOPB45_0978	PF10414	Sirohaem synthase dimerisation region
TOPB45_0978	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases
TOPB45_0978	PF14824	Sirohaem biosynthesis protein central
TOPB45_0979	PF00293	NUDIX domain
TOPB45_0980	PF02190	ATP-dependent protease La (LON) substrate-binding domain 
TOPB45_0980	PF05362	Lon protease (S16) C-terminal proteolytic domain
TOPB45_0980	PF00004	ATPase family associated with various cellular activities (AAA)
TOPB45_0981	PF01245	Ribosomal protein L19
TOPB45_0982	PF01351	Ribonuclease HII
TOPB45_0983	PF02021	Uncharacterised protein family UPF0102
TOPB45_0985	PF03477	ATP cone domain
TOPB45_0985	PF02867	Ribonucleotide reductase, barrel domain
TOPB45_0985	PF00317	Ribonucleotide reductase, all-alpha domain
TOPB45_0986	PF00742	Homoserine dehydrogenase
TOPB45_0986	PF01842	ACT domain
TOPB45_0986	PF03447	Homoserine dehydrogenase, NAD binding domain
TOPB45_0992	PF12169	DNA polymerase III subunits gamma and tau domain III
TOPB45_0993	PF02575	YbaB/EbfC DNA-binding family
TOPB45_0996	PF02481	DNA recombination-mediator protein A
TOPB45_0996	PF17782	DprA winged helix domain
TOPB45_0997	PF07690	Major Facilitator Superfamily
TOPB45_0998	PF02843	Phosphoribosylglycinamide synthetase, C domain
TOPB45_0998	PF01071	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
TOPB45_0998	PF02844	Phosphoribosylglycinamide synthetase, N domain
TOPB45_0999	PF00731	AIR carboxylase
TOPB45_1000	PF01206	Sulfurtransferase TusA
TOPB45_1000	PF00581	Rhodanese-like domain
TOPB45_1002	PF01041	DegT/DnrJ/EryC1/StrS aminotransferase family
TOPB45_1006	PF02355	Protein export membrane protein
TOPB45_1006	PF07549	SecD/SecF GG Motif
TOPB45_1007	PF02911	Formyl transferase, C-terminal domain
TOPB45_1007	PF00551	Formyl transferase
TOPB45_1008	PF00004	ATPase family associated with various cellular activities (AAA)
TOPB45_1008	PF10431	C-terminal, D2-small domain, of ClpB protein 
TOPB45_1008	PF07724	AAA domain (Cdc48 subfamily)
TOPB45_1008	PF17871	AAA lid domain
TOPB45_1008	PF02861	Clp amino terminal domain, pathogenicity island component
TOPB45_1009	PF00011	Hsp20/alpha crystallin family
TOPB45_1010	PF02769	AIR synthase related protein, C-terminal domain
TOPB45_1010	PF00586	AIR synthase related protein, N-terminal domain
TOPB45_1011	PF00334	Nucleoside diphosphate kinase
TOPB45_1013	PF02163	Peptidase family M50
TOPB45_1014	PF13180	PDZ domain
TOPB45_1014	PF03572	Peptidase family S41
TOPB45_1015	PF00318	Ribosomal protein S2
TOPB45_1016	PF00889	Elongation factor TS
TOPB45_1017	PF00696	Amino acid kinase family
TOPB45_1018	PF01765	Ribosome recycling factor
TOPB45_1019	PF01255	Putative undecaprenyl diphosphate synthase
TOPB45_1022	PF07478	D-ala D-ala ligase C-terminus
TOPB45_1022	PF01820	D-ala D-ala ligase N-terminus
TOPB45_1024	PF04972	BON domain
TOPB45_1025	PF16199	Radical_SAM C-terminal domain
TOPB45_1025	PF04055	Radical SAM superfamily
TOPB45_1027	PF00689	Cation transporting ATPase, C-terminus
TOPB45_1027	PF00690	Cation transporter/ATPase, N-terminus
TOPB45_1029	PF13932	GidA associated domain
TOPB45_1029	PF01134	Glucose inhibited division protein A
TOPB45_1032	PF04546	Sigma-70, non-essential region
TOPB45_1032	PF00140	Sigma-70 factor, region 1.2
TOPB45_1032	PF04542	Sigma-70 region 2 
TOPB45_1032	PF04539	Sigma-70 region 3
TOPB45_1032	PF03979	Sigma-70 factor, region 1.1
TOPB45_1032	PF04545	Sigma-70, region 4
TOPB45_1033	PF13361	UvrD-like helicase C-terminal domain
TOPB45_1033	PF00580	UvrD/REP helicase N-terminal domain
TOPB45_1036	PF00696	Amino acid kinase family
TOPB45_1037	PF00133	tRNA synthetases class I (I, L, M and V)
TOPB45_1037	PF08264	Anticodon-binding domain of tRNA
TOPB45_1037	PF10458	Valyl tRNA synthetase tRNA binding arm
TOPB45_1039	PF02463	RecF/RecN/SMC N terminal domain
TOPB45_1039	PF06470	SMC proteins Flexible Hinge Domain
TOPB45_1042	PF00391	PEP-utilising enzyme, mobile domain
TOPB45_1042	PF00224	Pyruvate kinase, barrel domain
TOPB45_1042	PF02887	Pyruvate kinase, alpha/beta domain
TOPB45_1045	PF01259	SAICAR synthetase
TOPB45_1048	PF00176	SNF2 family N-terminal domain
TOPB45_1048	PF00271	Helicase conserved C-terminal domain
TOPB45_1062	PF01131	DNA topoisomerase
TOPB45_1062	PF01751	Toprim domain
TOPB45_1063	PF08245	Mur ligase middle domain
TOPB45_1063	PF02875	Mur ligase family, glutamate ligase domain
TOPB45_1068	PF02687	FtsX-like permease family
TOPB45_1068	PF00005	ABC transporter
TOPB45_1068	PF12704	MacB-like periplasmic core domain
TOPB45_1069	PF02687	FtsX-like permease family
TOPB45_1069	PF00005	ABC transporter
TOPB45_1069	PF12704	MacB-like periplasmic core domain
TOPB45_1070	PF16576	Barrel-sandwich domain of CusB or HlyD membrane-fusion
TOPB45_1072	PF13520	Amino acid permease
TOPB45_1073	PF01914	MarC family integral membrane protein
TOPB45_1075	PF16198	tRNA pseudouridylate synthase B C-terminal domain
TOPB45_1075	PF01509	TruB family pseudouridylate synthase (N terminal domain)
TOPB45_1077	PF02033	Ribosome-binding factor A
TOPB45_1079	PF04760	Translation initiation factor IF-2, N-terminal region
TOPB45_1079	PF00009	Elongation factor Tu GTP binding domain
TOPB45_1079	PF11987	Translation-initiation factor 2
TOPB45_1080	PF02348	Cytidylyltransferase
TOPB45_1081	PF01875	Memo-like protein
TOPB45_1082	PF00749	tRNA synthetases class I (E and Q), catalytic domain
TOPB45_1083	PF08448	PAS fold
TOPB45_1083	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_1083	PF00563	EAL domain
TOPB45_1108	PF05362	Lon protease (S16) C-terminal proteolytic domain
TOPB45_1108	PF02190	ATP-dependent protease La (LON) substrate-binding domain 
TOPB45_1108	PF00004	ATPase family associated with various cellular activities (AAA)
TOPB45_1109	PF18211	Csm1 subunit domain B
TOPB45_1111	PF03787	RAMP superfamily
TOPB45_1113	PF03787	RAMP superfamily
TOPB45_1117	PF09827	CRISPR associated protein Cas2
TOPB45_1118	PF01867	CRISPR associated protein Cas1
TOPB45_1122	PF02656	Domain of unknown function (DUF202)
TOPB45_1123	PF00849	RNA pseudouridylate synthase
TOPB45_1123	PF01479	S4 domain
TOPB45_1124	PF02705	K+ potassium transporter
TOPB45_1125	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_1125	PF00072	Response regulator receiver domain
TOPB45_1128	PF01292	Prokaryotic cytochrome b561
TOPB45_1131	PF00579	tRNA synthetases class I (W and Y)
TOPB45_1132	PF12826	Helix-hairpin-helix motif
TOPB45_1132	PF03119	NAD-dependent DNA ligase C4 zinc finger domain
TOPB45_1132	PF03120	NAD-dependent DNA ligase OB-fold domain
TOPB45_1132	PF01653	NAD-dependent DNA ligase adenylation domain
TOPB45_1132	PF00533	BRCA1 C Terminus (BRCT) domain
TOPB45_1133	PF05140	ResB-like family 
TOPB45_1135	PF00005	ABC transporter
TOPB45_1137	PF03144	Elongation factor Tu domain 2
TOPB45_1137	PF00009	Elongation factor Tu GTP binding domain
TOPB45_1137	PF06421	GTP-binding protein LepA C-terminus
TOPB45_1137	PF00679	Elongation factor G C-terminus
TOPB45_1138	PF10502	Signal peptidase, peptidase S26 
TOPB45_1140	PF01895	PhoU domain
TOPB45_1141	PF01171	PP-loop family
TOPB45_1145	PF01479	S4 domain
TOPB45_1145	PF00849	RNA pseudouridylate synthase
TOPB45_1146	PF01545	Cation efflux family
TOPB45_1146	PF16916	Dimerisation domain of Zinc Transporter
TOPB45_1147	PF02390	Putative methyltransferase 
TOPB45_1147	PF04413	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
TOPB45_1149	PF01725	Ham1 family
TOPB45_1150	PF03725	3' exoribonuclease family, domain 2
TOPB45_1150	PF01138	3' exoribonuclease family, domain 1
TOPB45_1152	PF02774	Semialdehyde dehydrogenase, dimerisation domain
TOPB45_1152	PF01118	Semialdehyde dehydrogenase, NAD binding domain
TOPB45_1153	PF01402	Ribbon-helix-helix protein, copG family
TOPB45_1153	PF08753	NikR C terminal nickel binding domain
TOPB45_1154	PF00575	S1 RNA binding domain
TOPB45_1154	PF17876	Cold shock domain
TOPB45_1154	PF00773	RNB domain
TOPB45_1154	PF08206	Ribonuclease B OB domain
TOPB45_1156	PF00155	Aminotransferase class I and II
TOPB45_1157	PF01458	Uncharacterized protein family (UPF0051)
TOPB45_1158	PF00005	ABC transporter
TOPB45_1159	PF01555	DNA methylase
TOPB45_1161	PF00575	S1 RNA binding domain
TOPB45_1161	PF03725	3' exoribonuclease family, domain 2
TOPB45_1161	PF01138	3' exoribonuclease family, domain 1
TOPB45_1161	PF00013	KH domain
TOPB45_1161	PF03726	Polyribonucleotide nucleotidyltransferase, RNA binding domain
TOPB45_1162	PF01048	Phosphorylase superfamily
TOPB45_1163	PF00575	S1 RNA binding domain
TOPB45_1163	PF10150	Ribonuclease E/G family
TOPB45_1164	PF08645	Polynucleotide kinase 3 phosphatase
TOPB45_1165	PF01075	Glycosyltransferase family 9 (heptosyltransferase)
TOPB45_1166	PF00005	ABC transporter
TOPB45_1166	PF00664	ABC transporter transmembrane region
TOPB45_1167	PF01435	Peptidase family M48
TOPB45_1169	PF02666	Phosphatidylserine decarboxylase
TOPB45_1170	PF01066	CDP-alcohol phosphatidyltransferase
TOPB45_1171	PF04025	Domain of unknown function (DUF370)
TOPB45_1172	PF00625	Guanylate kinase
TOPB45_1173	PF00588	SpoU rRNA Methylase family
TOPB45_1173	PF08032	RNA 2'-O ribose methyltransferase substrate binding
TOPB45_1176	PF02577	Bifunctional nuclease
TOPB45_1180	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_1181	PF00072	Response regulator receiver domain
TOPB45_1181	PF01966	HD domain
TOPB45_1182	PF04023	FeoA domain
TOPB45_1183	PF07670	Nucleoside recognition
TOPB45_1183	PF04023	FeoA domain
TOPB45_1183	PF07664	Ferrous iron transport protein B C terminus
TOPB45_1183	PF17910	FeoB cytosolic helical domain
TOPB45_1183	PF02421	Ferrous iron transport protein B
TOPB45_1185	PF01230	HIT domain
TOPB45_1186	PF00133	tRNA synthetases class I (I, L, M and V)
TOPB45_1186	PF09334	tRNA synthetases class I (M)
TOPB45_1186	PF01588	Putative tRNA binding domain
TOPB45_1187	PF04468	PSP1 C-terminal conserved region
TOPB45_1188	PF04055	Radical SAM superfamily
TOPB45_1188	PF06463	Molybdenum Cofactor Synthesis C
TOPB45_1190	PF03966	Trm112p-like protein
TOPB45_1192	PF08207	Elongation factor P (EF-P) KOW-like domain
TOPB45_1192	PF09285	Elongation factor P, C-terminal
TOPB45_1192	PF01132	Elongation factor P (EF-P) OB domain
TOPB45_1193	PF01861	Branched-chain polyamine synthase A C-terminal domain
TOPB45_1195	PF00563	EAL domain
TOPB45_1195	PF03707	Bacterial signalling protein N terminal repeat
TOPB45_1195	PF00990	Diguanylate cyclase, GGDEF domain
TOPB45_1196	PF03477	ATP cone domain
TOPB45_1197	PF00215	Orotidine 5'-phosphate decarboxylase / HUMPS family
TOPB45_1203	PF13247	4Fe-4S dicluster domain
TOPB45_1205	PF07685	CobB/CobQ-like glutamine amidotransferase domain
TOPB45_1205	PF01656	CobQ/CobB/MinD/ParA nucleotide binding domain
TOPB45_1212	PF07660	Secretin and TonB N terminus short domain
TOPB45_1212	PF03958	Bacterial type II/III secretion system short domain
TOPB45_1212	PF00263	Bacterial type II and III secretion system protein
TOPB45_1212	PF11741	AMIN domain
TOPB45_1213	PF01134	Glucose inhibited division protein A
TOPB45_1214	PF02699	Preprotein translocase subunit
TOPB45_1215	PF01702	Queuine tRNA-ribosyltransferase
TOPB45_1216	PF00155	Aminotransferase class I and II
TOPB45_1219	PF00583	Acetyltransferase (GNAT) family
TOPB45_1219	PF01047	MarR family
TOPB45_1224	PF18395	Cas3 C-terminal domain
TOPB45_1224	PF18019	HD domain
TOPB45_1224	PF00270	DEAD/DEAH box helicase
TOPB45_1226	PF01867	CRISPR associated protein Cas1
TOPB45_1227	PF09827	CRISPR associated protein Cas2
TOPB45_1234	PF02417	Chromate transporter
TOPB45_1236	PF02894	Oxidoreductase family, C-terminal alpha/beta domain
TOPB45_1236	PF01408	Oxidoreductase family, NAD-binding Rossmann fold
TOPB45_1237	PF01041	DegT/DnrJ/EryC1/StrS aminotransferase family
TOPB45_1240	PF01206	Sulfurtransferase TusA
TOPB45_1242	PF00582	Universal stress protein family
TOPB45_1247	PF00512	His Kinase A (phospho-acceptor) domain
TOPB45_1247	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
TOPB45_1247	PF08448	PAS fold
TOPB45_1247	PF00072	Response regulator receiver domain
TOPB45_1247	PF13188	PAS domain
TOPB45_1248	PF00072	Response regulator receiver domain
TOPB45_1248	PF00158	Sigma-54 interaction domain
TOPB45_1248	PF02954	Bacterial regulatory protein, Fis family
TOPB45_1249	PF01980	tRNA-methyltransferase O
TOPB45_1251	PF00291	Pyridoxal-phosphate dependent enzyme
TOPB45_1252	PF02535	ZIP Zinc transporter
TOPB45_1255	PF01645	Conserved region in glutamate synthase
TOPB45_1255	PF04898	Glutamate synthase central domain
TOPB45_1255	PF00310	Glutamine amidotransferases class-II
TOPB45_1255	PF01493	GXGXG motif
TOPB45_1256	PF02540	NAD synthase
TOPB45_1257	PF03951	Glutamine synthetase, beta-Grasp domain
TOPB45_1257	PF00120	Glutamine synthetase, catalytic domain
TOPB45_1258	PF00158	Sigma-54 interaction domain
TOPB45_1258	PF01590	GAF domain
TOPB45_1258	PF02954	Bacterial regulatory protein, Fis family
TOPB45_1259	PF00117	Glutamine amidotransferase class-I
TOPB45_1259	PF00958	GMP synthase C terminal domain
TOPB45_1259	PF02540	NAD synthase
TOPB45_1260	PF00543	Nitrogen regulatory protein P-II
TOPB45_1262	PF03349	Outer membrane protein transport protein (OMPP1/FadL/TodX)
TOPB45_1263	PF13193	AMP-binding enzyme C-terminal domain
TOPB45_1263	PF01553	Acyltransferase
TOPB45_1263	PF00501	AMP-binding enzyme
TOPB45_1266	PF10609	NUBPL iron-transfer P-loop NTPase
TOPB45_1267	PF02562	PhoH-like protein
TOPB45_1268	PF02325	YGGT family
TOPB45_1269	PF02594	Uncharacterised ACR, YggU family COG1872
TOPB45_1270	PF01189	16S rRNA methyltransferase RsmB/F
TOPB45_1270	PF17125	N-terminal domain of 16S rRNA methyltransferase RsmF
TOPB45_1270	PF13636	RNA-binding PUA-like domain of methyltransferase RsmF
TOPB45_1271	PF00709	Adenylosuccinate synthetase
TOPB45_1272	PF02786	Carbamoyl-phosphate synthase L chain, ATP binding domain
TOPB45_1272	PF00289	Biotin carboxylase, N-terminal domain
TOPB45_1272	PF02785	Biotin carboxylase C-terminal domain
TOPB45_1273	PF17848	Acetyl-coA carboxylase zinc finger domain
TOPB45_1273	PF01039	Carboxyl transferase domain
TOPB45_1275	PF02237	Biotin protein ligase C terminal domain
TOPB45_1275	PF03099	Biotin/lipoate A/B protein ligase family
TOPB45_1276	PF02142	MGS-like domain
TOPB45_1276	PF02787	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
TOPB45_1276	PF02786	Carbamoyl-phosphate synthase L chain, ATP binding domain
TOPB45_1278	PF00005	ABC transporter
TOPB45_1282	PF00586	AIR synthase related protein, N-terminal domain
TOPB45_1282	PF02769	AIR synthase related protein, C-terminal domain
TOPB45_1283	PF02091	Glycyl-tRNA synthetase alpha subunit
TOPB45_1284	PF02092	Glycyl-tRNA synthetase beta subunit
TOPB45_1284	PF05746	DALR anticodon binding domain
TOPB45_1285	PF00009	Elongation factor Tu GTP binding domain
TOPB45_1285	PF09107	Elongation factor SelB, winged helix 
TOPB45_1285	PF09106	Elongation factor SelB, winged helix 
TOPB45_1285	PF09105	Elongation factor SelB, winged helix 
TOPB45_1285	PF03144	Elongation factor Tu domain 2
TOPB45_1286	PF05362	Lon protease (S16) C-terminal proteolytic domain
TOPB45_1286	PF13654	AAA domain
TOPB45_1287	PF00330	Aconitase family (aconitate hydratase)
TOPB45_1288	PF00694	Aconitase C-terminal domain
TOPB45_1289	PF03819	MazG nucleotide pyrophosphohydrolase domain
TOPB45_1290	PF00005	ABC transporter
TOPB45_1291	PF00950	ABC 3 transport family
TOPB45_1292	PF01026	TatD related DNase
TOPB45_1293	PF00152	tRNA synthetases class II (D, K and N) 
TOPB45_1293	PF02938	GAD domain
TOPB45_1293	PF01336	OB-fold nucleic acid binding domain
TOPB45_1295	PF03167	Uracil DNA glycosylase superfamily
TOPB45_1296	PF01012	Electron transfer flavoprotein domain
TOPB45_1296	PF00766	Electron transfer flavoprotein FAD-binding domain
TOPB45_1297	PF01012	Electron transfer flavoprotein domain
TOPB45_1298	PF00441	Acyl-CoA dehydrogenase, C-terminal domain
TOPB45_1298	PF02771	Acyl-CoA dehydrogenase, N-terminal domain
TOPB45_1298	PF02770	Acyl-CoA dehydrogenase, middle domain
TOPB45_1299	PF00109	Beta-ketoacyl synthase, N-terminal domain
TOPB45_1299	PF02801	Beta-ketoacyl synthase, C-terminal domain
TOPB45_1300	PF00501	AMP-binding enzyme
TOPB45_1300	PF13193	AMP-binding enzyme C-terminal domain
TOPB45_1303	PF00586	AIR synthase related protein, N-terminal domain
TOPB45_1303	PF02769	AIR synthase related protein, C-terminal domain
TOPB45_1303	PF18072	Formylglycinamide ribonucleotide amidotransferase linker domain
TOPB45_1305	PF00365	Phosphofructokinase
TOPB45_1307	PF14489	QueF-like protein
TOPB45_1309	PF00210	Ferritin-like domain
TOPB45_1310	PF00005	ABC transporter
TOPB45_1311	PF02361	Cobalt transport protein
TOPB45_1313	PF01891	Cobalt uptake substrate-specific transmembrane region
TOPB45_1318	PF00684	DnaJ central domain
TOPB45_1318	PF01556	DnaJ C terminal domain
TOPB45_1318	PF00226	DnaJ domain
TOPB45_1319	PF01739	CheR methyltransferase, SAM binding domain
TOPB45_1319	PF03705	CheR methyltransferase, all-alpha domain
TOPB45_1320	PF01339	CheB methylesterase
TOPB45_1320	PF00072	Response regulator receiver domain
TOPB45_1325	PF00072	Response regulator receiver domain
TOPB45_1326	PF04542	Sigma-70 region 2 
TOPB45_1326	PF04545	Sigma-70, region 4
TOPB45_1326	PF04539	Sigma-70 region 3
TOPB45_1327	PF10609	NUBPL iron-transfer P-loop NTPase
TOPB45_1328	PF02881	SRP54-type protein, helical bundle domain
TOPB45_1328	PF00448	SRP54-type protein, GTPase domain
TOPB45_1328	PF02978	Signal peptide binding domain
TOPB45_1329	PF00771	FHIPEP family
TOPB45_1330	PF01312	FlhB HrpN YscU SpaS Family
TOPB45_1332	PF01313	Bacterial export proteins, family 3
TOPB45_1333	PF00813	FliP family
TOPB45_1335	PF01052	Type III flagellar switch regulator (C-ring) FliN C-term
TOPB45_1336	PF01052	Type III flagellar switch regulator (C-ring) FliN C-term
TOPB45_1336	PF02154	Flagellar motor switch protein FliM
TOPB45_1339	PF01661	Macro domain
TOPB45_1345	PF00700	Bacterial flagellin C-terminal helical region
TOPB45_1345	PF00669	Bacterial flagellin N-terminal helical region
TOPB45_1347	PF04055	Radical SAM superfamily
TOPB45_1348	PF04545	Sigma-70, region 4
TOPB45_1348	PF04542	Sigma-70 region 2 
TOPB45_1348	PF00140	Sigma-70 factor, region 1.2
TOPB45_1351	PF03471	Transporter associated domain
TOPB45_1351	PF01595	Cyclin M transmembrane N-terminal domain
TOPB45_1351	PF00571	CBS domain
TOPB45_1352	PF00571	CBS domain
TOPB45_1352	PF03471	Transporter associated domain
TOPB45_1352	PF01595	Cyclin M transmembrane N-terminal domain
TOPB45_1355	PF13361	UvrD-like helicase C-terminal domain
TOPB45_1355	PF00580	UvrD/REP helicase N-terminal domain
TOPB45_1357	PF00270	DEAD/DEAH box helicase
TOPB45_1357	PF00271	Helicase conserved C-terminal domain
TOPB45_1357	PF03461	TRCF domain
TOPB45_1357	PF17757	UvrB interaction domain
TOPB45_1357	PF02559	CarD-like/TRCF domain
TOPB45_1359	PF01016	Ribosomal L27 protein
TOPB45_1360	PF02660	Glycerol-3-phosphate acyltransferase
TOPB45_1364	PF01434	Peptidase family M41
TOPB45_1364	PF06480	FtsH Extracellular
TOPB45_1364	PF17862	AAA+ lid domain
TOPB45_1364	PF00004	ATPase family associated with various cellular activities (AAA)
TOPB45_1365	PF00809	Pterin binding enzyme
TOPB45_1366	PF02457	DisA bacterial checkpoint controller nucleotide-binding
TOPB45_1368	PF02880	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
TOPB45_1368	PF02879	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
TOPB45_1368	PF02878	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
TOPB45_1368	PF00408	Phosphoglucomutase/phosphomannomutase, C-terminal domain
TOPB45_1371	PF10672	S-adenosylmethionine-dependent methyltransferase
TOPB45_1371	PF17785	PUA-like domain
TOPB45_1375	PF03749	Sugar fermentation stimulation protein RE domain
TOPB45_1375	PF17746	SfsA N-terminal OB domain
TOPB45_1376	PF08032	RNA 2'-O ribose methyltransferase substrate binding
TOPB45_1376	PF00588	SpoU rRNA Methylase family
TOPB45_1377	PF16360	GTP-binding GTPase Middle Region
TOPB45_1377	PF13167	GTP-binding GTPase N-terminal
TOPB45_1377	PF01926	50S ribosome-binding GTPase
TOPB45_1380	PF01380	SIS domain
TOPB45_1382	PF02224	Cytidylate kinase
TOPB45_1383	PF01029	NusB family
TOPB45_1384	PF02800	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
TOPB45_1384	PF00044	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
TOPB45_1385	PF01326	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
TOPB45_1385	PF02896	PEP-utilising enzyme, TIM barrel domain
TOPB45_1385	PF00391	PEP-utilising enzyme, mobile domain
TOPB45_1386	PF02800	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
TOPB45_1386	PF00044	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
TOPB45_1387	PF00583	Acetyltransferase (GNAT) family
TOPB45_1388	PF03668	P-loop ATPase protein family
TOPB45_1389	PF02482	Sigma 54 modulation protein / S30EA ribosomal protein
TOPB45_1390	PF04552	Sigma-54, DNA binding domain
TOPB45_1390	PF04963	Sigma-54 factor, core binding domain
TOPB45_1390	PF00309	Sigma-54 factor, Activator interacting domain (AID) 
TOPB45_1391	PF00005	ABC transporter
TOPB45_1391	PF12399	Branched-chain amino acid ATP-binding cassette transporter
TOPB45_1393	PF00118	TCP-1/cpn60 chaperonin family
TOPB45_1394	PF00166	Chaperonin 10 Kd subunit
TOPB45_1396	PF16200	C-terminal region of band_7
TOPB45_1396	PF01145	SPFH domain / Band 7 family
TOPB45_1398	PF00205	Thiamine pyrophosphate enzyme, central domain
TOPB45_1398	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
TOPB45_1398	PF02776	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
TOPB45_1399	PF01842	ACT domain
TOPB45_1399	PF10369	Small subunit of acetolactate synthase
TOPB45_1400	PF00456	Transketolase, thiamine diphosphate binding domain
TOPB45_1401	PF00902	Sec-independent protein translocase protein (TatC)
TOPB45_1402	PF02416	mttA/Hcf106 family
TOPB45_1403	PF00483	Nucleotidyl transferase
TOPB45_1405	PF08679	Dissimilatory sulfite reductase D (DsrD)
TOPB45_1406	PF03460	Nitrite/Sulfite reductase ferredoxin-like half domain
TOPB45_1406	PF01077	Nitrite and sulphite reductase 4Fe-4S domain
TOPB45_1407	PF03460	Nitrite/Sulfite reductase ferredoxin-like half domain
TOPB45_1407	PF01077	Nitrite and sulphite reductase 4Fe-4S domain
TOPB45_1409	PF02634	FdhD/NarQ family
TOPB45_1410	PF10996	Beta-Casp domain
TOPB45_1410	PF00753	Metallo-beta-lactamase superfamily
TOPB45_1410	PF07521	Zn-dependent metallo-hydrolase RNA specificity domain
TOPB45_1412	PF00830	Ribosomal L28 family
TOPB45_1413	PF02824	TGS domain
TOPB45_1413	PF04607	Region found in RelA / SpoT proteins
TOPB45_1413	PF13291	ACT domain
TOPB45_1414	PF02780	Transketolase, C-terminal domain
TOPB45_1414	PF02779	Transketolase, pyrimidine binding domain
TOPB45_1414	PF13292	1-deoxy-D-xylulose-5-phosphate synthase
TOPB45_1415	PF00348	Polyprenyl synthetase
TOPB45_1416	PF02609	Exonuclease VII small subunit
TOPB45_1417	PF02601	Exonuclease VII, large subunit
TOPB45_1417	PF13742	OB-fold nucleic acid binding domain
TOPB45_1422	PF10609	NUBPL iron-transfer P-loop NTPase
TOPB45_1422	PF01883	Iron-sulfur cluster assembly protein
TOPB45_1426	PF02082	Transcriptional regulator
TOPB45_1427	PF02322	Cytochrome bd terminal oxidase subunit II
TOPB45_1428	PF01654	Cytochrome bd terminal oxidase subunit I
TOPB45_1433	PF13603	Leucyl-tRNA synthetase, Domain 2
TOPB45_1433	PF00133	tRNA synthetases class I (I, L, M and V)
TOPB45_1433	PF08264	Anticodon-binding domain of tRNA
TOPB45_1433	PF09334	tRNA synthetases class I (M)
TOPB45_1434	PF00180	Isocitrate/isopropylmalate dehydrogenase
TOPB45_1435	PF03167	Uracil DNA glycosylase superfamily
TOPB45_1436	PF01957	NfeD-like C-terminal, partner-binding
TOPB45_1436	PF01972	Serine dehydrogenase proteinase
TOPB45_1438	PF03740	Pyridoxal phosphate biosynthesis protein PdxJ
TOPB45_1440	PF02127	Aminopeptidase I zinc metalloprotease (M18)
TOPB45_1442	PF01649	Ribosomal protein S20
TOPB45_1443	PF00679	Elongation factor G C-terminus
TOPB45_1443	PF03144	Elongation factor Tu domain 2
TOPB45_1443	PF00009	Elongation factor Tu GTP binding domain
TOPB45_1443	PF03764	Elongation factor G, domain IV
TOPB45_1443	PF14492	Elongation Factor G, domain II
TOPB45_1444	PF00994	Probable molybdopterin binding domain
TOPB45_1446	PF06050	2-hydroxyglutaryl-CoA dehydratase, D-component 
TOPB45_1447	PF01869	BadF/BadG/BcrA/BcrD ATPase family
TOPB45_1448	PF00126	Bacterial regulatory helix-turn-helix protein, lysR family
TOPB45_1448	PF03466	LysR substrate binding domain
TOPB45_1449	PF04879	Molybdopterin oxidoreductase Fe4S4 domain
TOPB45_1449	PF00384	Molybdopterin oxidoreductase
TOPB45_1449	PF01568	Molydopterin dinucleotide binding domain
TOPB45_1450	PF13247	4Fe-4S dicluster domain
TOPB45_1452	PF02606	Tetraacyldisaccharide-1-P 4'-kinase
TOPB45_1454	PF01230	HIT domain
TOPB45_1455	PF01479	S4 domain
TOPB45_1455	PF00579	tRNA synthetases class I (W and Y)
TOPB45_1457	PF03900	Porphobilinogen deaminase, C-terminal domain
TOPB45_1457	PF01379	Porphobilinogen deaminase, dipyromethane cofactor binding domain
TOPB45_1459	PF02754	Cysteine-rich domain
TOPB45_1460	PF01370	NAD dependent epimerase/dehydratase family
TOPB45_1461	PF03471	Transporter associated domain
TOPB45_1461	PF03741	Integral membrane protein TerC family
TOPB45_1461	PF00571	CBS domain
TOPB45_1462	PF00795	Carbon-nitrogen hydrolase
TOPB45_1463	PF02441	Flavoprotein
TOPB45_1464	PF00075	RNase H
TOPB45_1467	PF00015	Methyl-accepting chemotaxis protein (MCP) signalling domain
TOPB45_1467	PF00672	HAMP domain
TOPB45_1468	PF01584	CheW-like domain
TOPB45_1469	PF02895	Signal transducing histidine kinase, homodimeric domain
TOPB45_1469	PF07194	P2 response regulator binding domain
TOPB45_1469	PF01627	Hpt domain
TOPB45_1469	PF01584	CheW-like domain
TOPB45_1469	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
TOPB45_1470	PF02016	LD-carboxypeptidase N-terminal domain
TOPB45_1470	PF17676	LD-carboxypeptidase C-terminal domain
TOPB45_1471	PF03309	Type III pantothenate kinase
TOPB45_1476	PF01842	ACT domain
TOPB45_1476	PF01817	Chorismate mutase type II
TOPB45_1476	PF00800	Prephenate dehydratase
TOPB45_1478	PF13184	NusA-like KH domain
TOPB45_1478	PF00575	S1 RNA binding domain
TOPB45_1478	PF08529	NusA N-terminal domain
TOPB45_1479	PF02576	RimP N-terminal domain
TOPB45_1479	PF17384	RimP C-terminal SH3 domain
TOPB45_1481	PF00083	Sugar (and other) transporter
TOPB45_1482	PF00689	Cation transporting ATPase, C-terminus
TOPB45_1482	PF00690	Cation transporter/ATPase, N-terminus
TOPB45_1485	PF00712	DNA polymerase III beta subunit, N-terminal domain
TOPB45_1485	PF02767	DNA polymerase III beta subunit, central domain
TOPB45_1485	PF02768	DNA polymerase III beta subunit, C-terminal domain
TOPB45_1486	PF00204	DNA gyrase B
TOPB45_1486	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
TOPB45_1486	PF01751	Toprim domain
TOPB45_1486	PF00986	DNA gyrase B subunit, carboxyl terminus
TOPB45_1489	PF03916	Polysulphide reductase, NrfD
TOPB45_1490	PF13247	4Fe-4S dicluster domain
TOPB45_1492	PF02085	Class III cytochrome C family
TOPB45_1496	PF17760	UvrA interaction domain
TOPB45_1496	PF17755	UvrA DNA-binding domain
TOPB45_1496	PF00005	ABC transporter
TOPB45_1497	PF14716	Helix-hairpin-helix domain
TOPB45_1497	PF14791	DNA polymerase beta thumb 
TOPB45_1497	PF02811	PHP domain
TOPB45_1498	PF00768	D-alanyl-D-alanine carboxypeptidase
TOPB45_1498	PF07943	Penicillin-binding protein 5, C-terminal domain
TOPB45_1499	PF03721	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain
TOPB45_1499	PF03720	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain
TOPB45_1499	PF00984	UDP-glucose/GDP-mannose dehydrogenase family, central domain
TOPB45_1500	PF00753	Metallo-beta-lactamase superfamily
TOPB45_1501	PF01202	Shikimate kinase
TOPB45_1503	PF01488	Shikimate / quinate 5-dehydrogenase
TOPB45_1503	PF18317	Shikimate 5'-dehydrogenase C-terminal domain
TOPB45_1503	PF08501	Shikimate dehydrogenase substrate binding domain
TOPB45_1504	PF01487	Type I 3-dehydroquinase
TOPB45_1505	PF01808	AICARFT/IMPCHase bienzyme
TOPB45_1505	PF02142	MGS-like domain
TOPB45_1506	PF13186	Iron-sulfur cluster-binding domain
TOPB45_1506	PF04055	Radical SAM superfamily
TOPB45_1507	PF00072	Response regulator receiver domain
TOPB45_1507	PF00486	Transcriptional regulatory protein, C terminal
TOPB45_1508	PF06689	ClpX C4-type zinc finger
TOPB45_1508	PF07724	AAA domain (Cdc48 subfamily)
TOPB45_1508	PF10431	C-terminal, D2-small domain, of ClpB protein 
TOPB45_1509	PF17764	3′ DNA-binding domain (3′BD)
TOPB45_1509	PF18074	Primosomal protein N C-terminal domain
TOPB45_1509	PF18319	PriA DNA helicase Cys-rich region (CRR) domain
TOPB45_1509	PF04851	Type III restriction enzyme, res subunit
TOPB45_1509	PF00271	Helicase conserved C-terminal domain
TOPB45_1510	PF00483	Nucleotidyl transferase
TOPB45_1512	PF00437	Type II/IV secretion system protein
TOPB45_1513	PF00437	Type II/IV secretion system protein
TOPB45_1517	PF02637	GatB domain
TOPB45_1517	PF02934	GatB/GatE catalytic domain
TOPB45_1518	PF01008	Initiation factor 2 subunit family
TOPB45_1519	PF02629	CoA binding domain
TOPB45_1519	PF06971	Putative DNA-binding protein N-terminus
TOPB45_1520	PF00692	dUTPase
TOPB45_1521	PF02777	Iron/manganese superoxide dismutases, C-terminal domain
TOPB45_1521	PF00081	Iron/manganese superoxide dismutases, alpha-hairpin domain
TOPB45_1524	PF10531	SLBB domain
TOPB45_1525	PF04358	DsrC like protein
TOPB45_1526	PF14698	Argininosuccinate lyase C-terminal
TOPB45_1526	PF00206	Lyase
TOPB45_1526	PF00583	Acetyltransferase (GNAT) family
TOPB45_1528	PF03485	Arginyl tRNA synthetase N terminal domain
TOPB45_1528	PF05746	DALR anticodon binding domain
TOPB45_1528	PF00750	tRNA synthetases class I (R)
TOPB45_1530	PF00849	RNA pseudouridylate synthase
TOPB45_1530	PF01479	S4 domain
TOPB45_1532	PF04166	Pyridoxal phosphate biosynthetic protein PdxA
TOPB45_1533	PF00012	Hsp70 protein
TOPB45_1534	PF01025	GrpE
TOPB45_1535	PF01729	Quinolinate phosphoribosyl transferase, C-terminal domain
TOPB45_1535	PF02749	Quinolinate phosphoribosyl transferase, N-terminal domain
TOPB45_1536	PF01368	DHH family
TOPB45_1536	PF02833	DHHA2 domain
TOPB45_1538	PF01618	MotA/TolQ/ExbB proton channel family
TOPB45_1539	PF13677	Membrane MotB of proton-channel complex MotA/MotB 
TOPB45_1539	PF00691	OmpA family
TOPB45_1540	PF01926	50S ribosome-binding GTPase
TOPB45_1540	PF14714	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
TOPB45_1543	PF01168	Alanine racemase, N-terminal domain
TOPB45_1545	PF00401	ATP synthase, Delta/Epsilon chain, long alpha-helix domain
TOPB45_1545	PF02823	ATP synthase, Delta/Epsilon chain, beta-sandwich domain
TOPB45_1546	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain
TOPB45_1546	PF02874	ATP synthase alpha/beta family, beta-barrel domain
TOPB45_1547	PF00231	ATP synthase
TOPB45_1548	PF02874	ATP synthase alpha/beta family, beta-barrel domain
TOPB45_1548	PF00306	ATP synthase alpha/beta chain, C terminal domain
TOPB45_1548	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain
TOPB45_1549	PF00213	ATP synthase delta (OSCP) subunit
TOPB45_1552	PF01098	Cell cycle protein
TOPB45_1553	PF00905	Penicillin binding protein transpeptidase domain
TOPB45_1553	PF03717	Penicillin-binding Protein dimerisation domain
TOPB45_1555	PF04085	rod shape-determining protein MreC
TOPB45_1556	PF14821	Threonine synthase N terminus
TOPB45_1556	PF00291	Pyridoxal-phosphate dependent enzyme
TOPB45_1558	PF12706	Beta-lactamase superfamily domain
TOPB45_1560	PF03841	L-seryl-tRNA selenium transferase
TOPB45_1560	PF12390	Selenocysteine synthase N terminal
TOPB45_1561	PF00155	Aminotransferase class I and II
TOPB45_1562	PF00682	HMGL-like
TOPB45_1565	PF07196	Flagellin hook IN motif
TOPB45_1565	PF06429	Flagellar basal body rod FlgEFG protein C-terminal
TOPB45_1568	PF02119	Flagellar P-ring protein
TOPB45_1569	PF02107	Flagellar L-ring protein
TOPB45_1571	PF00460	Flagella basal body rod protein
TOPB45_1571	PF06429	Flagellar basal body rod FlgEFG protein C-terminal
TOPB45_1572	PF06429	Flagellar basal body rod FlgEFG protein C-terminal
TOPB45_1572	PF00460	Flagella basal body rod protein
TOPB45_1573	PF01103	Surface antigen
TOPB45_1573	PF07244	Surface antigen variable number repeat
TOPB45_1574	PF00005	ABC transporter
TOPB45_1576	PF00152	tRNA synthetases class II (D, K and N) 
TOPB45_1576	PF01336	OB-fold nucleic acid binding domain
TOPB45_1577	PF02899	Phage integrase, N-terminal SAM-like domain
TOPB45_1577	PF00589	Phage integrase family
TOPB45_1578	PF13188	PAS domain
TOPB45_1578	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
TOPB45_1578	PF08448	PAS fold
TOPB45_1578	PF00512	His Kinase A (phospho-acceptor) domain
TOPB45_1578	PF00072	Response regulator receiver domain
TOPB45_1580	PF00313	'Cold-shock' DNA-binding domain
TOPB45_1582	PF14010	Phosphoenolpyruvate carboxylase
TOPB45_1583	PF01264	Chorismate synthase
TOPB45_1584	PF01128	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
TOPB45_1586	PF00330	Aconitase family (aconitate hydratase)
TOPB45_1589	PF00117	Glutamine amidotransferase class-I
TOPB45_1589	PF06418	CTP synthase N-terminus
TOPB45_1591	PF02445	Quinolinate synthetase A protein
TOPB45_1594	PF12072	Domain of unknown function (DUF3552)
TOPB45_1594	PF00013	KH domain
TOPB45_1594	PF01966	HD domain
TOPB45_1595	PF13277	YmdB-like protein
TOPB45_1596	PF01327	Polypeptide deformylase
TOPB45_1598	PF01558	Pyruvate ferredoxin/flavodoxin oxidoreductase
TOPB45_1600	PF17147	Pyruvate:ferredoxin oxidoreductase core domain II
TOPB45_1600	PF01855	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg
TOPB45_1601	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
TOPB45_1604	PF06508	Queuosine biosynthesis protein QueC
TOPB45_1606	PF01475	Ferric uptake regulator family
TOPB45_1607	PF01784	NIF3 (NGG1p interacting factor 3)
TOPB45_1609	PF01300	Telomere recombination
TOPB45_1610	PF07992	Pyridine nucleotide-disulphide oxidoreductase
TOPB45_1612	PF02910	Fumarate reductase flavoprotein C-term
TOPB45_1612	PF00890	FAD binding domain
TOPB45_1613	PF10143	2,3-bisphosphoglycerate-independent phosphoglycerate mutase
TOPB45_1613	PF01676	Metalloenzyme superfamily
TOPB45_1614	PF00902	Sec-independent protein translocase protein (TatC)
TOPB45_1615	PF02416	mttA/Hcf106 family
TOPB45_1616	PF01168	Alanine racemase, N-terminal domain
TOPB45_1616	PF00842	Alanine racemase, C-terminal domain
TOPB45_1617	PF07992	Pyridine nucleotide-disulphide oxidoreductase
TOPB45_1618	PF03884	DNA gyrase inhibitor YacG
TOPB45_1620	PF00206	Lyase
TOPB45_1620	PF14698	Argininosuccinate lyase C-terminal
TOPB45_1625	PF02082	Transcriptional regulator
TOPB45_1626	PF02403	Seryl-tRNA synthetase N-terminal domain
TOPB45_1626	PF00587	tRNA synthetase class II core domain (G, H, P, S and T)
TOPB45_1627	PF00565	Staphylococcal nuclease homologue
TOPB45_1629	PF02561	Flagellar protein FliS
TOPB45_1632	PF00185	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
TOPB45_1632	PF02729	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
TOPB45_1634	PF08352	Oligopeptide/dipeptide transporter, C-terminal region
TOPB45_1634	PF00005	ABC transporter
TOPB45_1635	PF00005	ABC transporter
TOPB45_1635	PF08352	Oligopeptide/dipeptide transporter, C-terminal region
