N186_03280 35b2621330262a73d58b16caebe10571 348 SUPERFAMILY SSF102114 27 211 4.71E-22 T 31-10-2018 N186_03280 35b2621330262a73d58b16caebe10571 348 Pfam PF04055 Radical SAM superfamily 34 143 7.7E-11 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_03280 35b2621330262a73d58b16caebe10571 348 SMART SM00729 27 232 0.0034 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_03280 35b2621330262a73d58b16caebe10571 348 Pfam PF13353 4Fe-4S single cluster domain 25 129 1.0E-6 T 31-10-2018 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 PRINTS PR00315 GTP-binding elongation factor signature 142 151 1.2E-11 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 PRINTS PR00315 GTP-binding elongation factor signature 22 35 1.2E-11 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 PRINTS PR00315 GTP-binding elongation factor signature 106 117 1.2E-11 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 PRINTS PR00315 GTP-binding elongation factor signature 90 100 1.2E-11 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Gene3D G3DSA:2.40.30.10 258 386 3.3E-28 T 31-10-2018 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Gene3D G3DSA:3.30.70.870 391 468 2.6E-25 T 31-10-2018 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Pfam PF00009 Elongation factor Tu GTP binding domain 19 256 4.0E-59 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Hamap MF_00054_A Elongation factor G [fusA]. 1 728 40.766 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Gene3D G3DSA:3.30.230.10 475 724 1.0E-85 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Gene3D G3DSA:3.30.70.240 469 721 1.0E-85 T 31-10-2018 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 SMART SM00889 508 622 8.1E-21 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Pfam PF00679 Elongation factor G C-terminus 625 710 2.5E-23 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Pfam PF14492 Elongation Factor G, domain II 389 462 8.6E-24 T 31-10-2018 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Gene3D G3DSA:3.40.50.300 6 220 4.7E-64 T 31-10-2018 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 SUPERFAMILY SSF54980 627 715 1.19E-22 T 31-10-2018 IPR035647 EF-G domain III/V-like N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 20 153 3.7E-17 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Pfam PF03144 Elongation factor Tu domain 2 305 371 5.5E-15 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 SUPERFAMILY SSF54980 389 464 1.01E-21 T 31-10-2018 IPR035647 EF-G domain III/V-like N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 SMART SM00838 624 711 4.9E-39 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 SUPERFAMILY SSF54211 466 626 1.04E-50 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 SUPERFAMILY SSF52540 8 256 1.15E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 721 8.4E-272 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 Pfam PF03764 Elongation factor G, domain IV 516 620 1.7E-27 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 N186_04420 d7121b34d8f33ccc932347c4b343cae7 734 SUPERFAMILY SSF50447 258 377 5.11E-33 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_03265 1423e7e8d5138409ba83708f45450875 339 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 35 320 47.975 T 31-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 N186_03265 1423e7e8d5138409ba83708f45450875 339 Pfam PF08068 DKCLD (NUC011) domain 12 58 6.9E-16 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 N186_03265 1423e7e8d5138409ba83708f45450875 339 SUPERFAMILY SSF55120 13 244 1.97E-73 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 N186_03265 1423e7e8d5138409ba83708f45450875 339 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 63 113 1.9E-14 T 31-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 N186_03265 1423e7e8d5138409ba83708f45450875 339 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 115 175 4.1E-7 T 31-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 N186_03265 1423e7e8d5138409ba83708f45450875 339 SUPERFAMILY SSF88697 244 327 4.97E-21 T 31-10-2018 IPR015947 PUA-like superfamily N186_03265 1423e7e8d5138409ba83708f45450875 339 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 176 243 2.4E-21 T 31-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 N186_03265 1423e7e8d5138409ba83708f45450875 339 Gene3D G3DSA:3.30.2350.10 35 238 8.5E-135 T 31-10-2018 N186_03265 1423e7e8d5138409ba83708f45450875 339 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 244 321 4.1E-8 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 N186_03265 1423e7e8d5138409ba83708f45450875 339 SMART SM00359 246 320 9.4E-16 T 31-10-2018 IPR002478 PUA domain GO:0003723 N186_03265 1423e7e8d5138409ba83708f45450875 339 Pfam PF01472 PUA domain 246 316 7.0E-18 T 31-10-2018 IPR002478 PUA domain GO:0003723 N186_03265 1423e7e8d5138409ba83708f45450875 339 Gene3D G3DSA:2.30.130.70 19 327 8.5E-135 T 31-10-2018 N186_03265 1423e7e8d5138409ba83708f45450875 339 SMART SM01136 10 58 1.0E-24 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 N186_03265 1423e7e8d5138409ba83708f45450875 339 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 13 330 8.1E-134 T 31-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 N186_07795 34c4314b4ad33c1fb11a51e7817e68b2 345 SUPERFAMILY SSF52540 3 273 7.36E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07795 34c4314b4ad33c1fb11a51e7817e68b2 345 Pfam PF01637 ATPase domain predominantly from Archaea 15 240 2.5E-18 T 31-10-2018 IPR011579 ATPase domain GO:0005524 N186_07795 34c4314b4ad33c1fb11a51e7817e68b2 345 Gene3D G3DSA:1.10.8.60 201 275 1.5E-21 T 31-10-2018 N186_07795 34c4314b4ad33c1fb11a51e7817e68b2 345 Gene3D G3DSA:1.10.10.10 277 343 9.8E-13 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_07795 34c4314b4ad33c1fb11a51e7817e68b2 345 SUPERFAMILY SSF46785 276 341 1.47E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_07795 34c4314b4ad33c1fb11a51e7817e68b2 345 Gene3D G3DSA:3.40.50.300 1 199 9.4E-48 T 31-10-2018 N186_01440 3dbe4ad7fd0838c8a01a5a9cc17f31c1 105 SUPERFAMILY SSF46785 23 95 7.92E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_01440 3dbe4ad7fd0838c8a01a5a9cc17f31c1 105 Pfam PF13463 Winged helix DNA-binding domain 22 81 3.2E-7 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 N186_01440 3dbe4ad7fd0838c8a01a5a9cc17f31c1 105 Gene3D G3DSA:1.10.10.10 15 96 1.1E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_03715 486b183619c0a781010c2df84289f7a7 226 Gene3D G3DSA:1.10.1670.10 21 220 7.6E-58 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 N186_03715 486b183619c0a781010c2df84289f7a7 226 SMART SM00478 50 200 1.3E-33 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 N186_03715 486b183619c0a781010c2df84289f7a7 226 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 50 177 2.4E-14 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 N186_03715 486b183619c0a781010c2df84289f7a7 226 PIRSF PIRSF001435 11 224 3.1E-32 T 31-10-2018 N186_03715 486b183619c0a781010c2df84289f7a7 226 SUPERFAMILY SSF48150 14 220 1.73E-58 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 N186_03715 486b183619c0a781010c2df84289f7a7 226 SMART SM00525 201 220 9.4E-5 T 31-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 N186_03715 486b183619c0a781010c2df84289f7a7 226 Gene3D G3DSA:1.10.340.30 32 144 7.6E-58 T 31-10-2018 N186_03715 486b183619c0a781010c2df84289f7a7 226 Pfam PF00633 Helix-hairpin-helix motif 111 138 6.7E-7 T 31-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 N186_02715 6e09c24fb0f66e41e6b5f6045923c050 471 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 143 361 8.7E-65 T 31-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 N186_02715 6e09c24fb0f66e41e6b5f6045923c050 471 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 352 361 - T 31-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 N186_02715 6e09c24fb0f66e41e6b5f6045923c050 471 Gene3D G3DSA:3.40.50.12240 14 470 1.1E-165 T 31-10-2018 N186_02715 6e09c24fb0f66e41e6b5f6045923c050 471 SUPERFAMILY SSF52540 89 366 1.3E-79 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02715 6e09c24fb0f66e41e6b5f6045923c050 471 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 15 470 55.581 T 31-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_09660 8c6658e5012b11e656db4be287f56f48 242 SUPERFAMILY SSF52540 7 235 7.67E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09660 8c6658e5012b11e656db4be287f56f48 242 Pfam PF00005 ABC transporter 24 167 5.1E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09660 8c6658e5012b11e656db4be287f56f48 242 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_09660 8c6658e5012b11e656db4be287f56f48 242 Gene3D G3DSA:3.40.50.300 4 241 2.5E-53 T 31-10-2018 N186_09660 8c6658e5012b11e656db4be287f56f48 242 SMART SM00382 33 217 1.5E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 9 99 5.7E-16 T 31-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 Gene3D G3DSA:3.40.50.720 2 161 9.2E-35 T 31-10-2018 N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 7 264 23.174 T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 SUPERFAMILY SSF51735 8 157 1.22E-23 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 SUPERFAMILY SSF48179 158 268 1.39E-29 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 Gene3D G3DSA:1.10.3730.10 162 266 9.8E-32 T 31-10-2018 N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 159 263 1.7E-32 T 31-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 9 264 2.2E-73 T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 N186_00815 0d04d5810de5c7a7a09ad89d4ab866c7 279 PIRSF PIRSF000193 6 267 4.6E-65 T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 N186_06960 36ededa69b17893a3910cd1d647911dd 292 SUPERFAMILY SSF161098 8 291 3.18E-59 T 31-10-2018 IPR035906 MetI-like superfamily N186_06960 36ededa69b17893a3910cd1d647911dd 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 281 2.0E-20 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_06960 36ededa69b17893a3910cd1d647911dd 292 Gene3D G3DSA:1.10.3720.10 4 279 1.3E-53 T 31-10-2018 IPR035906 MetI-like superfamily N186_04270 807383b61c404527fafd1b8f9785eb35 228 Gene3D G3DSA:3.40.1280.10 3 225 1.3E-67 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal N186_04270 807383b61c404527fafd1b8f9785eb35 228 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 4 223 34.324 T 31-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 N186_04270 807383b61c404527fafd1b8f9785eb35 228 Pfam PF03587 EMG1/NEP1 methyltransferase 6 218 4.4E-44 T 31-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 N186_04270 807383b61c404527fafd1b8f9785eb35 228 SUPERFAMILY SSF75217 3 225 7.19E-56 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases N186_07595 1156370f104a59d4925b124a264d8ede 328 Pfam PF00005 ABC transporter 34 187 1.6E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_07595 1156370f104a59d4925b124a264d8ede 328 Gene3D G3DSA:3.40.50.300 1 328 5.2E-98 T 31-10-2018 N186_07595 1156370f104a59d4925b124a264d8ede 328 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_07595 1156370f104a59d4925b124a264d8ede 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 324 1.6E-27 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_07595 1156370f104a59d4925b124a264d8ede 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 304 1.1E-19 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_07595 1156370f104a59d4925b124a264d8ede 328 SUPERFAMILY SSF52540 4 259 1.26E-73 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07595 1156370f104a59d4925b124a264d8ede 328 SMART SM00382 43 237 8.8E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_09245 98b27512d2fa76003622ae6ed34f6aa3 128 Pfam PF01850 PIN domain 36 111 8.8E-10 T 31-10-2018 IPR002716 PIN domain N186_09245 98b27512d2fa76003622ae6ed34f6aa3 128 Gene3D G3DSA:3.40.50.1010 3 126 1.0E-8 T 31-10-2018 N186_09245 98b27512d2fa76003622ae6ed34f6aa3 128 SUPERFAMILY SSF88723 11 121 4.25E-14 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_04885 ea65694d9b917424c99ec7ecf923cfc2 164 Pfam PF01472 PUA domain 88 160 3.8E-9 T 31-10-2018 IPR002478 PUA domain GO:0003723 N186_04885 ea65694d9b917424c99ec7ecf923cfc2 164 SMART SM00359 86 163 5.8E-4 T 31-10-2018 IPR002478 PUA domain GO:0003723 N186_04885 ea65694d9b917424c99ec7ecf923cfc2 164 SUPERFAMILY SSF88802 7 81 2.09E-10 T 31-10-2018 N186_04885 ea65694d9b917424c99ec7ecf923cfc2 164 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 68 160 3.7E-7 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 N186_04885 ea65694d9b917424c99ec7ecf923cfc2 164 Gene3D G3DSA:2.30.130.10 85 162 3.5E-18 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 N186_04885 ea65694d9b917424c99ec7ecf923cfc2 164 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 17 80 1.8E-8 T 31-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 N186_04885 ea65694d9b917424c99ec7ecf923cfc2 164 Gene3D G3DSA:3.10.450.90 10 82 3.2E-8 T 31-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 N186_04885 ea65694d9b917424c99ec7ecf923cfc2 164 SUPERFAMILY SSF88697 85 161 1.77E-11 T 31-10-2018 IPR015947 PUA-like superfamily N186_06435 e97ba57fb305d814a928f44a9f83f94d 357 Gene3D G3DSA:1.10.150.20 48 110 2.1E-13 T 31-10-2018 N186_06435 e97ba57fb305d814a928f44a9f83f94d 357 SUPERFAMILY SSF47794 39 104 2.2E-9 T 31-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 N186_06435 e97ba57fb305d814a928f44a9f83f94d 357 Gene3D G3DSA:3.40.50.300 111 357 1.1E-83 T 31-10-2018 N186_06435 e97ba57fb305d814a928f44a9f83f94d 357 SMART SM00382 142 327 2.8E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_06435 e97ba57fb305d814a928f44a9f83f94d 357 Pfam PF08423 Rad51 108 356 1.2E-96 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 N186_06435 e97ba57fb305d814a928f44a9f83f94d 357 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 49 356 4.6E-136 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 N186_06435 e97ba57fb305d814a928f44a9f83f94d 357 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 46 356 77.137 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 N186_06435 e97ba57fb305d814a928f44a9f83f94d 357 SUPERFAMILY SSF52540 122 356 1.15E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06435 e97ba57fb305d814a928f44a9f83f94d 357 PIRSF PIRSF005856 37 357 1.7E-123 T 31-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 N186_02965 f5ca59ab9954e46be6cf2c855935fabb 183 Pfam PF00827 Ribosomal L15 2 163 1.9E-62 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02965 f5ca59ab9954e46be6cf2c855935fabb 183 SUPERFAMILY SSF54189 1 161 1.06E-60 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02965 f5ca59ab9954e46be6cf2c855935fabb 183 SMART SM01384 2 182 1.6E-87 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02965 f5ca59ab9954e46be6cf2c855935fabb 183 Gene3D G3DSA:3.40.1120.10 1 178 6.3E-62 T 31-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02965 f5ca59ab9954e46be6cf2c855935fabb 183 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 31-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01060 07c68a21d1b61db18a2a094e5d41921d 336 Gene3D G3DSA:1.10.3210.10 149 311 1.7E-9 T 31-10-2018 N186_01060 07c68a21d1b61db18a2a094e5d41921d 336 Pfam PF00782 Dual specificity phosphatase, catalytic domain 11 102 2.6E-6 T 31-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 N186_01060 07c68a21d1b61db18a2a094e5d41921d 336 Pfam PF01966 HD domain 166 279 1.0E-10 T 31-10-2018 IPR006674 HD domain N186_01060 07c68a21d1b61db18a2a094e5d41921d 336 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 87 97 - T 31-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 N186_01060 07c68a21d1b61db18a2a094e5d41921d 336 SUPERFAMILY SSF52799 8 139 1.16E-18 T 31-10-2018 IPR029021 Protein-tyrosine phosphatase-like N186_01060 07c68a21d1b61db18a2a094e5d41921d 336 SUPERFAMILY SSF109604 166 328 4.36E-15 T 31-10-2018 N186_01060 07c68a21d1b61db18a2a094e5d41921d 336 Gene3D G3DSA:3.90.190.10 2 138 3.5E-14 T 31-10-2018 IPR029021 Protein-tyrosine phosphatase-like N186_01840 39bbd34f406fcaa898e56767b9555d91 890 SUPERFAMILY SSF81660 336 532 5.23E-56 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 Pfam PF00689 Cation transporting ATPase, C-terminus 714 887 3.7E-39 T 31-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 601 720 3.3E-36 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 349 5.4E-42 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 330 336 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 550 560 3.5E-42 T 31-10-2018 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 654 666 3.5E-42 T 31-10-2018 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 3.5E-42 T 31-10-2018 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 630 649 3.5E-42 T 31-10-2018 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 3.5E-42 T 31-10-2018 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 539 3.5E-42 T 31-10-2018 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 487 505 1.8E-21 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 602 618 1.8E-21 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 662 687 1.8E-21 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 630 646 1.8E-21 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 SUPERFAMILY SSF56784 326 735 3.91E-67 T 31-10-2018 IPR036412 HAD-like superfamily N186_01840 39bbd34f406fcaa898e56767b9555d91 890 Gene3D G3DSA:3.40.1110.10 338 535 0.0 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 Pfam PF00702 haloacid dehalogenase-like hydrolase 327 644 2.7E-25 T 31-10-2018 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 Gene3D G3DSA:3.40.50.1000 325 675 0.0 T 31-10-2018 IPR023214 HAD superfamily N186_01840 39bbd34f406fcaa898e56767b9555d91 890 SUPERFAMILY SSF81653 117 226 1.44E-29 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 SMART SM00831 7 80 3.5E-29 T 31-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 Pfam PF00122 E1-E2 ATPase 115 308 3.8E-52 T 31-10-2018 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 Pfam PF00690 Cation transporter/ATPase, N-terminus 8 75 9.4E-19 T 31-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 SUPERFAMILY SSF81665 7 888 8.5E-123 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 Gene3D G3DSA:1.20.1110.10 58 885 0.0 T 31-10-2018 N186_01840 39bbd34f406fcaa898e56767b9555d91 890 Gene3D G3DSA:2.70.150.10 23 230 0.0 T 31-10-2018 N186_08185 e5c89bd43911e070ab00aa07b554ba21 652 Pfam PF11329 Protein of unknown function (DUF3131) 46 383 4.5E-44 T 31-10-2018 IPR021478 Protein of unknown function DUF3131 N186_05400 30e2ca68b8a6ea8c4c6d8111845fdb8d 251 PIRSF PIRSF037724 4 251 2.2E-83 T 31-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted N186_05400 30e2ca68b8a6ea8c4c6d8111845fdb8d 251 SMART SM00530 35 91 1.8E-10 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 N186_05400 30e2ca68b8a6ea8c4c6d8111845fdb8d 251 Gene3D G3DSA:1.10.260.40 31 91 1.3E-11 T 31-10-2018 N186_05400 30e2ca68b8a6ea8c4c6d8111845fdb8d 251 Pfam PF01381 Helix-turn-helix 36 82 4.4E-10 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 N186_05400 30e2ca68b8a6ea8c4c6d8111845fdb8d 251 SUPERFAMILY SSF47413 30 82 3.07E-11 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 N186_04465 8a67515365a65a61338e80a7f3da3f8d 339 Hamap MF_00700 DNA primase small subunit PriS [priS]. 1 330 21.391 T 31-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 N186_04465 8a67515365a65a61338e80a7f3da3f8d 339 SUPERFAMILY SSF56747 1 333 3.92E-72 T 31-10-2018 N186_04465 8a67515365a65a61338e80a7f3da3f8d 339 Pfam PF01896 DNA primase small subunit 99 265 4.5E-19 T 31-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 N186_02010 5d03905d4286bd5e9cc501af254e66bb 551 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 163 173 0.0026 T 31-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site N186_02010 5d03905d4286bd5e9cc501af254e66bb 551 SUPERFAMILY SSF160980 6 206 8.63E-34 T 31-10-2018 N186_02010 5d03905d4286bd5e9cc501af254e66bb 551 Gene3D G3DSA:3.40.50.10640 4 252 5.7E-31 T 31-10-2018 N186_02010 5d03905d4286bd5e9cc501af254e66bb 551 SUPERFAMILY SSF160980 413 532 4.05E-5 T 31-10-2018 N186_02010 5d03905d4286bd5e9cc501af254e66bb 551 TIGRFAM TIGR01897 cas_MJ1666: CRISPR-associated protein, MJ1666 family 6 204 3.5E-33 T 31-10-2018 IPR010171 CRISPR-associated protein, MJ1666 N186_02010 5d03905d4286bd5e9cc501af254e66bb 551 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 9 512 1.2E-19 T 31-10-2018 IPR019016 CRISPR-associated DxTHG protein N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 SUPERFAMILY SSF63737 23 203 2.09E-34 T 31-10-2018 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 Pfam PF01433 Peptidase family M1 domain 215 439 2.6E-52 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 Pfam PF13646 HEAT repeats 700 783 2.7E-8 T 31-10-2018 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 Pfam PF13646 HEAT repeats 600 682 5.2E-13 T 31-10-2018 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 Gene3D G3DSA:1.25.10.10 642 814 1.6E-17 T 31-10-2018 IPR011989 Armadillo-like helical N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 SMART SM00567 E-Z type HEAT repeats 612 641 0.032 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 SMART SM00567 E-Z type HEAT repeats 547 576 1200.0 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 SMART SM00567 E-Z type HEAT repeats 580 609 0.029 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 SMART SM00567 E-Z type HEAT repeats 710 740 99.0 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 SMART SM00567 E-Z type HEAT repeats 645 674 1.4E-4 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 SMART SM00567 E-Z type HEAT repeats 742 771 290.0 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 Gene3D G3DSA:1.25.10.110 553 637 1.5E-6 T 31-10-2018 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 SUPERFAMILY SSF48371 566 790 4.68E-20 T 31-10-2018 IPR016024 Armadillo-type fold N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 Gene3D G3DSA:1.10.390.60 205 444 3.4E-65 T 31-10-2018 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 SUPERFAMILY SSF55486 210 450 1.61E-70 T 31-10-2018 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 Gene3D G3DSA:2.60.40.1730 26 202 3.5E-31 T 31-10-2018 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 139 154 2.4E-16 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 186 201 2.4E-16 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 295 310 2.4E-16 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 263 273 2.4E-16 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 N186_07295 883b770a1cfad2d25e56e144a26f12b1 823 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 314 326 2.4E-16 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 N186_07305 9e13e4da33397fbf0a73189989c3125a 323 SUPERFAMILY SSF51430 1 311 6.68E-87 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily N186_07305 9e13e4da33397fbf0a73189989c3125a 323 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 134 151 - T 31-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 N186_07305 9e13e4da33397fbf0a73189989c3125a 323 PRINTS PR00069 Aldo-keto reductase signature 42 66 5.6E-11 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 N186_07305 9e13e4da33397fbf0a73189989c3125a 323 PRINTS PR00069 Aldo-keto reductase signature 134 151 5.6E-11 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 N186_07305 9e13e4da33397fbf0a73189989c3125a 323 PRINTS PR00069 Aldo-keto reductase signature 101 119 5.6E-11 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 N186_07305 9e13e4da33397fbf0a73189989c3125a 323 Gene3D G3DSA:3.20.20.100 1 317 6.7E-90 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily N186_07305 9e13e4da33397fbf0a73189989c3125a 323 Pfam PF00248 Aldo/keto reductase family 15 305 1.9E-62 T 31-10-2018 IPR023210 NADP-dependent oxidoreductase domain N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 SUPERFAMILY SSF64153 2 245 1.57E-68 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 Pfam PF01256 Carbohydrate kinase 248 501 7.5E-53 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 224 509 22.577 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 Gene3D G3DSA:3.40.1190.20 230 519 2.3E-82 T 31-10-2018 IPR029056 Ribokinase-like N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 213 27.853 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 3 213 2.6E-55 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 Pfam PF03853 YjeF-related protein N-terminus 25 192 1.9E-52 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 231 505 9.9E-64 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 Gene3D G3DSA:3.40.50.10260 1 220 2.9E-72 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 PIRSF PIRSF017184 1 511 7.7E-141 T 31-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 N186_07520 4d1f5bd21838051dacd2d21d3fc89ab7 524 SUPERFAMILY SSF53613 229 507 1.03E-73 T 31-10-2018 IPR029056 Ribokinase-like N186_05585 4813c36e140e1e39c4275086e7833dd5 251 SUPERFAMILY SSF52540 4 238 2.03E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05585 4813c36e140e1e39c4275086e7833dd5 251 Gene3D G3DSA:3.40.50.300 3 248 1.1E-72 T 31-10-2018 N186_05585 4813c36e140e1e39c4275086e7833dd5 251 PRINTS PR01874 DNA repair protein radA signature 16 44 8.3E-6 T 31-10-2018 N186_05585 4813c36e140e1e39c4275086e7833dd5 251 PRINTS PR01874 DNA repair protein radA signature 169 197 8.3E-6 T 31-10-2018 N186_05585 4813c36e140e1e39c4275086e7833dd5 251 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 4 241 5.2E-137 T 31-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like N186_05585 4813c36e140e1e39c4275086e7833dd5 251 Hamap MF_01076 UPF0273 protein . 4 246 57.486 T 31-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like N186_05585 4813c36e140e1e39c4275086e7833dd5 251 Pfam PF06745 KaiC 7 238 1.4E-86 T 31-10-2018 IPR014774 KaiC-like domain N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 534 540 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Pfam PF04945 YHS domain 5 50 3.2E-18 T 31-10-2018 IPR007029 YHS domain N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Gene3D G3DSA:2.70.150.20 323 436 2.5E-31 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Gene3D G3DSA:3.40.1110.10 543 663 1.6E-81 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 303 808 9.6E-78 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Pfam PF00122 E1-E2 ATPase 331 510 1.6E-49 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 SUPERFAMILY SSF56784 530 837 1.87E-48 T 31-10-2018 IPR036412 HAD-like superfamily N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Pfam PF00702 haloacid dehalogenase-like hydrolase 528 744 1.1E-34 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 SUPERFAMILY SSF55008 63 124 6.41E-10 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 SUPERFAMILY SSF55008 139 190 2.75E-6 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 267 839 4.9E-160 T 31-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 SUPERFAMILY SSF81653 334 430 8.24E-26 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 ProSitePatterns PS01229 Hypothetical cof family signature 2. 731 753 - T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 SUPERFAMILY SSF47240 7 50 3.24E-9 T 31-10-2018 IPR009078 Ferritin-like superfamily N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Gene3D G3DSA:3.30.70.100 137 204 3.4E-6 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 SMART SM00746 6 44 2.4E-12 T 31-10-2018 IPR011017 TRASH domain N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 254 839 1.3E-132 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Gene3D G3DSA:1.10.620.20 2 66 7.8E-11 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 731 750 1.4E-21 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 678 688 1.4E-21 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 546 1.4E-21 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 754 766 1.4E-21 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 379 393 1.4E-21 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Pfam PF00403 Heavy-metal-associated domain 64 122 2.9E-8 T 31-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Gene3D G3DSA:3.40.50.1000 513 781 1.6E-81 T 31-10-2018 IPR023214 HAD superfamily N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 Gene3D G3DSA:3.30.70.100 67 126 8.4E-10 T 31-10-2018 N186_00695 6739d84e8397d36165fc70b0fb302a5b 848 SUPERFAMILY SSF81665 301 523 1.44E-8 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 N186_05840 76b142ce8a2073ac4403b77d4d9aa4c3 229 SUPERFAMILY SSF51351 6 220 5.37E-45 T 31-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05840 76b142ce8a2073ac4403b77d4d9aa4c3 229 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 10 214 2.1E-62 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05840 76b142ce8a2073ac4403b77d4d9aa4c3 229 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 8 227 42.406 T 31-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 N186_05840 76b142ce8a2073ac4403b77d4d9aa4c3 229 Pfam PF00121 Triosephosphate isomerase 10 126 1.7E-11 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05840 76b142ce8a2073ac4403b77d4d9aa4c3 229 Gene3D G3DSA:3.20.20.70 3 227 5.1E-87 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_02865 dcf59fd4e1f3a56624a5a6bcdccbcfb4 187 SUPERFAMILY SSF55144 5 186 7.32E-42 T 31-10-2018 IPR009097 Cyclic phosphodiesterase N186_02865 dcf59fd4e1f3a56624a5a6bcdccbcfb4 187 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 5 186 2.6E-47 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 N186_02865 dcf59fd4e1f3a56624a5a6bcdccbcfb4 187 Pfam PF02834 LigT like Phosphoesterase 96 178 4.0E-10 T 31-10-2018 IPR014051 Phosphoesterase, HXTX N186_02865 dcf59fd4e1f3a56624a5a6bcdccbcfb4 187 Pfam PF02834 LigT like Phosphoesterase 17 94 1.1E-16 T 31-10-2018 IPR014051 Phosphoesterase, HXTX N186_02865 dcf59fd4e1f3a56624a5a6bcdccbcfb4 187 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 5 186 25.91 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 N186_02865 dcf59fd4e1f3a56624a5a6bcdccbcfb4 187 Gene3D G3DSA:3.90.1140.10 5 187 2.9E-49 T 31-10-2018 N186_04380 756b8bcdcf71b4fdfe62be57c4d43925 255 Gene3D G3DSA:3.40.1160.10 2 253 5.1E-59 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily N186_04380 756b8bcdcf71b4fdfe62be57c4d43925 255 SUPERFAMILY SSF53633 2 243 8.25E-35 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily N186_04380 756b8bcdcf71b4fdfe62be57c4d43925 255 Pfam PF00696 Amino acid kinase family 1 233 7.1E-46 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 N186_04380 756b8bcdcf71b4fdfe62be57c4d43925 255 PRINTS PR00474 Glutamate 5-kinase family signature 209 229 3.9E-7 T 31-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 N186_04380 756b8bcdcf71b4fdfe62be57c4d43925 255 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 3.9E-7 T 31-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 N186_04380 756b8bcdcf71b4fdfe62be57c4d43925 255 PRINTS PR00474 Glutamate 5-kinase family signature 97 111 3.9E-7 T 31-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 N186_04380 756b8bcdcf71b4fdfe62be57c4d43925 255 PIRSF PIRSF016496 1 253 3.0E-72 T 31-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 N186_04125 a3f4f7beeab329d9e51f0249ed51c3a8 237 Pfam PF01061 ABC-2 type transporter 11 201 8.8E-10 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 N186_04125 a3f4f7beeab329d9e51f0249ed51c3a8 237 PIRSF PIRSF006648 16 234 7.2E-14 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_06245 c80f2e1deed59bdd13f47ea48f80b82f 376 Gene3D G3DSA:3.50.50.60 4 348 3.6E-97 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_06245 c80f2e1deed59bdd13f47ea48f80b82f 376 SUPERFAMILY SSF54373 237 305 4.51E-5 T 31-10-2018 N186_06245 c80f2e1deed59bdd13f47ea48f80b82f 376 SUPERFAMILY SSF51905 1 364 3.11E-52 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_06245 c80f2e1deed59bdd13f47ea48f80b82f 376 Pfam PF01266 FAD dependent oxidoreductase 3 344 2.4E-55 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 N186_06245 c80f2e1deed59bdd13f47ea48f80b82f 376 Gene3D G3DSA:3.30.9.10 81 304 3.6E-97 T 31-10-2018 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 61 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 Gene3D G3DSA:1.10.730.10 647 831 1.3E-47 T 31-10-2018 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 Gene3D G3DSA:1.10.30.30 885 946 3.1E-8 T 31-10-2018 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 641 7.3E-186 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 SUPERFAMILY SSF47323 652 877 4.67E-50 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 Pfam PF08264 Anticodon-binding domain of tRNA 689 838 3.0E-32 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 Gene3D G3DSA:3.90.740.10 198 400 1.1E-224 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 2.1E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 394 409 2.1E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 520 533 2.1E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 559 568 2.1E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 222 245 2.1E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 6 852 6.9E-285 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1055 12.885 T 31-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 SUPERFAMILY SSF52374 5 649 1.38E-128 T 31-10-2018 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 SUPERFAMILY SSF50677 201 396 1.99E-56 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 N186_01575 a24a784bbc010845af0b651ecaa297dd 1061 Gene3D G3DSA:3.40.50.620 15 628 1.1E-224 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_01090 6910844d88cbbb9ee00c863c3c9513fd 138 Gene3D G3DSA:3.30.460.10 9 101 2.2E-13 T 31-10-2018 N186_01090 6910844d88cbbb9ee00c863c3c9513fd 138 Pfam PF01909 Nucleotidyltransferase domain 21 96 1.2E-5 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_01090 6910844d88cbbb9ee00c863c3c9513fd 138 SUPERFAMILY SSF81301 7 113 5.72E-17 T 31-10-2018 N186_06635 a23a2e125ea33af56beb17c9b8286b53 691 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 8.8E-31 T 31-10-2018 N186_06635 a23a2e125ea33af56beb17c9b8286b53 691 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 262 288 8.8E-31 T 31-10-2018 N186_06635 a23a2e125ea33af56beb17c9b8286b53 691 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 452 471 8.8E-31 T 31-10-2018 N186_06635 a23a2e125ea33af56beb17c9b8286b53 691 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 261 8.8E-31 T 31-10-2018 N186_06635 a23a2e125ea33af56beb17c9b8286b53 691 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 4 631 1.4E-122 T 31-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06635 a23a2e125ea33af56beb17c9b8286b53 691 Pfam PF00361 Proton-conducting membrane transporter 177 459 6.2E-55 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06635 a23a2e125ea33af56beb17c9b8286b53 691 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 64 115 1.7E-11 T 31-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_01175 b7c2701a7f606c8944c05a719f114248 184 Pfam PF11563 Protoglobin 11 143 6.8E-12 T 31-10-2018 N186_01175 b7c2701a7f606c8944c05a719f114248 184 SUPERFAMILY SSF46458 9 126 2.88E-6 T 31-10-2018 IPR009050 Globin-like superfamily N186_01175 b7c2701a7f606c8944c05a719f114248 184 Gene3D G3DSA:1.10.490.10 9 159 4.8E-15 T 31-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 Pfam PF13180 PDZ domain 231 301 2.3E-10 T 31-10-2018 IPR001478 PDZ domain GO:0005515 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 Gene3D G3DSA:2.40.10.120 2 207 1.7E-67 T 31-10-2018 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 Gene3D G3DSA:2.30.42.10 210 307 1.2E-22 T 31-10-2018 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 SUPERFAMILY SSF50156 211 305 8.54E-20 T 31-10-2018 IPR036034 PDZ superfamily GO:0005515 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 SMART SM00228 212 294 4.5E-8 T 31-10-2018 IPR001478 PDZ domain GO:0005515 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 Pfam PF13365 Trypsin-like peptidase domain 38 176 5.8E-33 T 31-10-2018 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 SUPERFAMILY SSF50494 5 208 1.4E-60 T 31-10-2018 IPR009003 Peptidase S1, PA clan N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 PRINTS PR00834 HtrA/DegQ protease family signature 68 88 2.9E-31 T 31-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 PRINTS PR00834 HtrA/DegQ protease family signature 47 59 2.9E-31 T 31-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 PRINTS PR00834 HtrA/DegQ protease family signature 147 164 2.9E-31 T 31-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 PRINTS PR00834 HtrA/DegQ protease family signature 169 186 2.9E-31 T 31-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 PRINTS PR00834 HtrA/DegQ protease family signature 252 264 2.9E-31 T 31-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 N186_08905 a2e8d34be3a30b1b438ed5b2c3d31100 307 PRINTS PR00834 HtrA/DegQ protease family signature 108 132 2.9E-31 T 31-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 N186_01710 0d8f3a61e302ad73cb847b87d11580ed 513 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 91 105 4.3E-7 T 31-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 N186_01710 0d8f3a61e302ad73cb847b87d11580ed 513 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 189 200 4.3E-7 T 31-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 N186_01710 0d8f3a61e302ad73cb847b87d11580ed 513 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 125 143 4.3E-7 T 31-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 N186_01710 0d8f3a61e302ad73cb847b87d11580ed 513 Pfam PF01039 Carboxyl transferase domain 26 509 1.5E-184 T 31-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 N186_01710 0d8f3a61e302ad73cb847b87d11580ed 513 SUPERFAMILY SSF52096 213 491 5.12E-91 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily N186_01710 0d8f3a61e302ad73cb847b87d11580ed 513 Gene3D G3DSA:3.90.226.10 253 508 9.9E-93 T 31-10-2018 N186_01710 0d8f3a61e302ad73cb847b87d11580ed 513 Gene3D G3DSA:3.90.226.10 9 252 5.6E-88 T 31-10-2018 N186_01710 0d8f3a61e302ad73cb847b87d11580ed 513 SUPERFAMILY SSF52096 17 251 1.01E-74 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily N186_05220 81eabbb0c4d22540fc2e4735c684ea5f 261 Pfam PF00005 ABC transporter 22 177 8.0E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_05220 81eabbb0c4d22540fc2e4735c684ea5f 261 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_05220 81eabbb0c4d22540fc2e4735c684ea5f 261 SMART SM00382 30 224 1.1E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_05220 81eabbb0c4d22540fc2e4735c684ea5f 261 Gene3D G3DSA:3.40.50.300 5 254 1.3E-67 T 31-10-2018 N186_05220 81eabbb0c4d22540fc2e4735c684ea5f 261 SUPERFAMILY SSF52540 4 236 6.63E-62 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03070 c28c34c9123a0f38078731ccd65e4927 449 PIRSF PIRSF001529 1 444 9.8E-132 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 241 419 2.3E-33 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 TIGRFAM TIGR00414 serS: serine--tRNA ligase 4 436 2.6E-147 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 SUPERFAMILY SSF55681 151 437 6.44E-80 T 31-10-2018 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 SUPERFAMILY SSF46589 4 109 2.41E-20 T 31-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 441 36.659 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 5.9E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 PRINTS PR00981 Seryl-tRNA synthetase signature 282 294 5.9E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 PRINTS PR00981 Seryl-tRNA synthetase signature 334 347 5.9E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 PRINTS PR00981 Seryl-tRNA synthetase signature 369 385 5.9E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 PRINTS PR00981 Seryl-tRNA synthetase signature 294 307 5.9E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 Gene3D G3DSA:1.10.287.40 2 101 4.6E-18 T 31-10-2018 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 Gene3D G3DSA:3.30.930.10 102 446 5.1E-120 T 31-10-2018 N186_03070 c28c34c9123a0f38078731ccd65e4927 449 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 3 103 3.0E-17 T 31-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 N186_00610 19587aa50354942ebe10ece3bbafe0e0 734 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 240 425 8.4E-10 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_00610 19587aa50354942ebe10ece3bbafe0e0 734 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 532 728 6.9E-16 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_00610 19587aa50354942ebe10ece3bbafe0e0 734 SUPERFAMILY SSF161098 454 725 4.95E-41 T 31-10-2018 IPR035906 MetI-like superfamily N186_00610 19587aa50354942ebe10ece3bbafe0e0 734 Gene3D G3DSA:1.10.3720.10 202 435 7.1E-48 T 31-10-2018 IPR035906 MetI-like superfamily N186_00610 19587aa50354942ebe10ece3bbafe0e0 734 SUPERFAMILY SSF161098 142 431 6.32E-37 T 31-10-2018 IPR035906 MetI-like superfamily N186_00610 19587aa50354942ebe10ece3bbafe0e0 734 Gene3D G3DSA:1.10.3720.10 455 730 1.1E-41 T 31-10-2018 IPR035906 MetI-like superfamily N186_02945 22f55574ef72bc19f60fa5fb08da04b7 301 SUPERFAMILY SSF53271 3 162 3.88E-36 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_02945 22f55574ef72bc19f60fa5fb08da04b7 301 Pfam PF00156 Phosphoribosyl transferase domain 154 249 3.4E-15 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 N186_02945 22f55574ef72bc19f60fa5fb08da04b7 301 SMART SM01400 4 120 2.4E-33 T 31-10-2018 N186_02945 22f55574ef72bc19f60fa5fb08da04b7 301 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 5 295 5.7E-75 T 31-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 N186_02945 22f55574ef72bc19f60fa5fb08da04b7 301 SUPERFAMILY SSF53271 87 289 6.56E-35 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_02945 22f55574ef72bc19f60fa5fb08da04b7 301 Gene3D G3DSA:3.40.50.2020 150 280 1.1E-79 T 31-10-2018 N186_02945 22f55574ef72bc19f60fa5fb08da04b7 301 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 120 1.5E-25 T 31-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 N186_02945 22f55574ef72bc19f60fa5fb08da04b7 301 Gene3D G3DSA:3.40.50.2020 10 293 1.1E-79 T 31-10-2018 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Pfam PF04563 RNA polymerase beta subunit 26 397 3.5E-52 T 31-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Pfam PF04560 RNA polymerase Rpb2, domain 7 1032 1123 5.7E-30 T 31-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Pfam PF04561 RNA polymerase Rpb2, domain 2 188 350 2.1E-33 T 31-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Gene3D G3DSA:3.90.1800.10 1017 1125 3.6E-40 T 31-10-2018 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Pfam PF04565 RNA polymerase Rpb2, domain 3 418 482 1.1E-26 T 31-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 517 1127 3.6E-302 T 31-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Gene3D G3DSA:3.90.1100.10 19 175 3.4E-15 T 31-10-2018 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Gene3D G3DSA:3.90.1100.10 338 503 5.3E-45 T 31-10-2018 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Pfam PF00562 RNA polymerase Rpb2, domain 6 657 1030 1.5E-125 T 31-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Gene3D G3DSA:2.40.50.150 687 879 1.2E-137 T 31-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Pfam PF04567 RNA polymerase Rpb2, domain 5 609 647 6.4E-11 T 31-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 SUPERFAMILY SSF64484 12 1125 0.0 T 31-10-2018 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Gene3D G3DSA:2.40.270.10 658 1015 1.2E-137 T 31-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 ProSitePatterns PS01166 RNA polymerases beta chain signature. 883 895 - T 31-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Gene3D G3DSA:3.90.1110.10 176 337 3.5E-53 T 31-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02340 d8e248c9b2df997adc64f9740c9548f5 1129 Pfam PF04566 RNA polymerase Rpb2, domain 4 517 588 1.8E-21 T 31-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_04130 f1bd9533d7b786fb1e8b954d8c9a7327 445 SUPERFAMILY SSF52540 26 230 4.09E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04130 f1bd9533d7b786fb1e8b954d8c9a7327 445 Pfam PF13635 Domain of unknown function (DUF4143) 251 381 1.9E-13 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 N186_04130 f1bd9533d7b786fb1e8b954d8c9a7327 445 Pfam PF13173 AAA domain 35 167 2.1E-36 T 31-10-2018 N186_03840 1f3a4384c23e930bed831610e4db064b 134 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 79 96 - T 31-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 N186_03840 1f3a4384c23e930bed831610e4db064b 134 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 27 119 2.1E-31 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 N186_03840 1f3a4384c23e930bed831610e4db064b 134 PRINTS PR00884 Ribosomal protein HS6 signature 15 26 2.9E-28 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03840 1f3a4384c23e930bed831610e4db064b 134 PRINTS PR00884 Ribosomal protein HS6 signature 59 70 2.9E-28 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03840 1f3a4384c23e930bed831610e4db064b 134 PRINTS PR00884 Ribosomal protein HS6 signature 100 116 2.9E-28 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03840 1f3a4384c23e930bed831610e4db064b 134 PRINTS PR00884 Ribosomal protein HS6 signature 49 59 2.9E-28 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03840 1f3a4384c23e930bed831610e4db064b 134 PRINTS PR00884 Ribosomal protein HS6 signature 86 96 2.9E-28 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03840 1f3a4384c23e930bed831610e4db064b 134 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 86 100 1.8E-22 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family N186_03840 1f3a4384c23e930bed831610e4db064b 134 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 41 55 1.8E-22 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family N186_03840 1f3a4384c23e930bed831610e4db064b 134 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 60 73 1.8E-22 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family N186_03840 1f3a4384c23e930bed831610e4db064b 134 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 76 86 1.8E-22 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family N186_03840 1f3a4384c23e930bed831610e4db064b 134 SUPERFAMILY SSF55315 15 129 1.57E-39 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like N186_03840 1f3a4384c23e930bed831610e4db064b 134 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 12 131 33.291 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03840 1f3a4384c23e930bed831610e4db064b 134 Gene3D G3DSA:3.30.1330.30 7 134 2.9E-43 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like N186_03840 1f3a4384c23e930bed831610e4db064b 134 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 15 131 1.3E-53 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_04615 b4275246b616296b76243265d8e57845 336 SUPERFAMILY SSF102114 21 211 3.92E-30 T 31-10-2018 N186_04615 b4275246b616296b76243265d8e57845 336 Pfam PF04055 Radical SAM superfamily 34 202 3.4E-19 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_04615 b4275246b616296b76243265d8e57845 336 SMART SM00729 28 246 2.1E-7 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_04615 b4275246b616296b76243265d8e57845 336 Gene3D G3DSA:3.20.20.70 23 272 1.2E-26 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_07390 abfb10dee8c5b841334c8519d6e385bc 480 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 244 421 1.1E-20 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 N186_07390 abfb10dee8c5b841334c8519d6e385bc 480 Gene3D G3DSA:3.30.420.40 235 474 6.3E-42 T 31-10-2018 N186_07390 abfb10dee8c5b841334c8519d6e385bc 480 SUPERFAMILY SSF53067 236 462 4.96E-34 T 31-10-2018 N186_07390 abfb10dee8c5b841334c8519d6e385bc 480 PIRSF PIRSF000538 1 474 7.0E-56 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 N186_07390 abfb10dee8c5b841334c8519d6e385bc 480 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 214 8.9E-23 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 N186_07390 abfb10dee8c5b841334c8519d6e385bc 480 Gene3D G3DSA:3.30.420.40 1 232 6.6E-42 T 31-10-2018 N186_07390 abfb10dee8c5b841334c8519d6e385bc 480 SUPERFAMILY SSF53067 4 229 7.59E-36 T 31-10-2018 N186_01630 667d5402755f9587de91ce0787c85134 217 SMART SM00525 191 211 1.4E-4 T 31-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 N186_01630 667d5402755f9587de91ce0787c85134 217 SUPERFAMILY SSF48150 20 214 3.93E-48 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 N186_01630 667d5402755f9587de91ce0787c85134 217 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 192 208 - T 31-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 N186_01630 667d5402755f9587de91ce0787c85134 217 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 192 208 3.6E-4 T 31-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 N186_01630 667d5402755f9587de91ce0787c85134 217 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 31 174 1.3E-14 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 N186_01630 667d5402755f9587de91ce0787c85134 217 SMART SM00478 35 190 3.0E-27 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 N186_01630 667d5402755f9587de91ce0787c85134 217 Gene3D G3DSA:1.10.1670.10 138 208 2.9E-48 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 N186_01630 667d5402755f9587de91ce0787c85134 217 Gene3D G3DSA:1.10.340.30 22 137 2.9E-48 T 31-10-2018 N186_01630 667d5402755f9587de91ce0787c85134 217 PIRSF PIRSF001435 2 217 2.1E-50 T 31-10-2018 N186_06370 12da3c983d1a467147ad0460f26e70dd 187 SUPERFAMILY SSF52540 8 173 1.06E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06370 12da3c983d1a467147ad0460f26e70dd 187 Hamap MF_00796 Nucleoside-triphosphatase . 7 183 28.981 T 31-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 N186_06370 12da3c983d1a467147ad0460f26e70dd 187 Gene3D G3DSA:3.40.50.300 6 182 2.7E-51 T 31-10-2018 N186_06370 12da3c983d1a467147ad0460f26e70dd 187 Pfam PF03266 NTPase 9 175 5.6E-57 T 31-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 N186_06370 12da3c983d1a467147ad0460f26e70dd 187 SMART SM00382 5 166 9.5E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 148 246 5.6E-20 T 31-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 1.2E-6 T 31-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 166 185 1.7E-13 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 87 101 1.7E-13 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 200 213 1.7E-13 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 228 243 1.7E-13 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 88 97 - T 31-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 SUPERFAMILY SSF55957 351 454 5.23E-18 T 31-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 SUPERFAMILY SSF53738 256 356 3.34E-8 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 SUPERFAMILY SSF53738 148 248 1.33E-19 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 385 449 3.1E-12 T 31-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 Gene3D G3DSA:3.30.310.50 370 457 1.3E-17 T 31-10-2018 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 Gene3D G3DSA:3.40.120.10 249 354 4.3E-34 T 31-10-2018 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 Gene3D G3DSA:3.40.120.10 1 144 1.0E-32 T 31-10-2018 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 126 1.8E-26 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 Gene3D G3DSA:3.40.120.10 169 349 4.3E-34 T 31-10-2018 N186_09365 a6bb61faa8bb3f1d5f919eea1269cfb5 466 SUPERFAMILY SSF53738 2 162 2.47E-28 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_04900 61e7f21136153463fd7e0e4baa0d5c13 184 PIRSF PIRSF016123 7 184 7.1E-78 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 N186_04900 61e7f21136153463fd7e0e4baa0d5c13 184 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 9 183 41.689 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 N186_04900 61e7f21136153463fd7e0e4baa0d5c13 184 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 62 184 8.0E-38 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 N186_04900 61e7f21136153463fd7e0e4baa0d5c13 184 Gene3D G3DSA:3.40.1280.10 9 184 3.2E-70 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal N186_04900 61e7f21136153463fd7e0e4baa0d5c13 184 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 62 181 8.1E-50 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 N186_04900 61e7f21136153463fd7e0e4baa0d5c13 184 SUPERFAMILY SSF75217 9 181 1.12E-65 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases N186_02630 a85556c31faf35b29627f46a3eb0d764 198 SMART SM01022 6 105 4.1E-19 T 31-10-2018 IPR007374 ASCH domain N186_02630 a85556c31faf35b29627f46a3eb0d764 198 SUPERFAMILY SSF88697 3 104 8.2E-19 T 31-10-2018 IPR015947 PUA-like superfamily N186_02630 a85556c31faf35b29627f46a3eb0d764 198 Pfam PF04266 ASCH domain 8 103 2.7E-14 T 31-10-2018 IPR007374 ASCH domain N186_08835 adb39f613e55f9f744cb8d9876d7b8d0 329 SUPERFAMILY SSF50129 2 165 2.28E-42 T 31-10-2018 IPR011032 GroES-like superfamily N186_08835 adb39f613e55f9f744cb8d9876d7b8d0 329 Pfam PF00107 Zinc-binding dehydrogenase 172 290 1.1E-10 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 N186_08835 adb39f613e55f9f744cb8d9876d7b8d0 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 125 1.5E-27 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 N186_08835 adb39f613e55f9f744cb8d9876d7b8d0 329 SUPERFAMILY SSF51735 133 299 2.01E-23 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_08835 adb39f613e55f9f744cb8d9876d7b8d0 329 Gene3D G3DSA:3.40.50.720 144 275 1.2E-67 T 31-10-2018 N186_08835 adb39f613e55f9f744cb8d9876d7b8d0 329 Gene3D G3DSA:3.90.180.10 14 300 1.2E-67 T 31-10-2018 N186_08670 bef47d21fed85fe2abccc4f235c2add6 383 SUPERFAMILY SSF103473 4 379 1.57E-43 T 31-10-2018 IPR036259 MFS transporter superfamily N186_08670 bef47d21fed85fe2abccc4f235c2add6 383 Pfam PF07690 Major Facilitator Superfamily 30 308 2.3E-26 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_08670 bef47d21fed85fe2abccc4f235c2add6 383 Gene3D G3DSA:1.20.1250.20 2 187 1.3E-21 T 31-10-2018 N186_08670 bef47d21fed85fe2abccc4f235c2add6 383 Gene3D G3DSA:1.20.1250.20 224 383 4.0E-12 T 31-10-2018 N186_00190 2356242ff94e3fca134b1ef8abb2f7f7 211 Gene3D G3DSA:3.50.30.50 1 210 5.1E-63 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 N186_00190 2356242ff94e3fca134b1ef8abb2f7f7 211 SUPERFAMILY SSF102198 1 210 6.41E-62 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 N186_00190 2356242ff94e3fca134b1ef8abb2f7f7 211 Pfam PF04199 Putative cyclase 4 156 5.9E-34 T 31-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 N186_01390 cce1a1edc223cc7a1a9c2d35019347c6 614 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 207 8.0E-74 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_01390 cce1a1edc223cc7a1a9c2d35019347c6 614 SUPERFAMILY SSF48310 216 610 3.27E-102 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_01390 cce1a1edc223cc7a1a9c2d35019347c6 614 Gene3D G3DSA:1.10.599.10 240 599 2.1E-109 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 N186_01390 cce1a1edc223cc7a1a9c2d35019347c6 614 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 223 599 2.1E-96 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_01390 cce1a1edc223cc7a1a9c2d35019347c6 614 Gene3D G3DSA:1.10.569.10 242 420 2.1E-109 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 N186_01390 cce1a1edc223cc7a1a9c2d35019347c6 614 SMART SM00790 6 208 2.4E-103 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_01390 cce1a1edc223cc7a1a9c2d35019347c6 614 Gene3D G3DSA:3.60.9.10 3 212 2.1E-79 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily N186_01390 cce1a1edc223cc7a1a9c2d35019347c6 614 SUPERFAMILY SSF56228 4 211 5.36E-69 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily N186_09580 90b51fadef279ea37f3d6d1b9ad0fe99 837 SUPERFAMILY SSF52540 7 825 2.42E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09580 90b51fadef279ea37f3d6d1b9ad0fe99 837 Gene3D G3DSA:3.40.50.300 589 812 1.2E-23 T 31-10-2018 N186_09580 90b51fadef279ea37f3d6d1b9ad0fe99 837 Gene3D G3DSA:3.40.50.300 3 292 1.9E-33 T 31-10-2018 N186_09580 90b51fadef279ea37f3d6d1b9ad0fe99 837 Pfam PF13476 AAA domain 6 232 6.0E-19 T 31-10-2018 IPR038729 Rad50/SbcC-type AAA domain N186_09580 90b51fadef279ea37f3d6d1b9ad0fe99 837 SUPERFAMILY SSF52540 498 809 3.07E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 Gene3D G3DSA:1.20.1110.10 540 785 3.9E-38 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 Gene3D G3DSA:3.40.50.1000 314 326 2.7E-70 T 31-10-2018 IPR023214 HAD superfamily N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 Gene3D G3DSA:3.40.50.1000 467 507 4.5E-11 T 31-10-2018 IPR023214 HAD superfamily N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 Pfam PF00702 haloacid dehalogenase-like hydrolase 313 570 2.0E-25 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 SUPERFAMILY SSF81660 338 469 3.27E-8 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 319 325 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 Pfam PF00122 E1-E2 ATPase 121 297 6.2E-47 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 SUPERFAMILY SSF81665 12 789 1.83E-57 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 SUPERFAMILY SSF56784 316 654 1.86E-39 T 31-10-2018 IPR036412 HAD-like superfamily N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 530 637 2.3E-23 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 91 505 4.8E-56 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 Gene3D G3DSA:1.20.1110.10 62 313 2.7E-70 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 SUPERFAMILY SSF81653 122 218 6.93E-30 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 588 613 8.1E-28 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 719 740 8.1E-28 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 557 573 8.1E-28 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 428 446 8.1E-28 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 529 545 8.1E-28 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 Gene3D G3DSA:2.70.150.10 26 221 2.7E-70 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 317 331 4.6E-34 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 470 4.6E-34 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 580 592 4.6E-34 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 576 4.6E-34 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 491 4.6E-34 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 4.6E-34 T 31-10-2018 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 Pfam PF00690 Cation transporter/ATPase, N-terminus 15 77 8.6E-13 T 31-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 TIGRFAM TIGR01647 ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase 31 763 3.1E-215 T 31-10-2018 IPR006534 P-type ATPase, subfamily IIIA GO:0008553|GO:0016021|GO:0120029 KEGG: 00190+3.6.3.6 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 Gene3D G3DSA:3.40.1110.10 449 466 4.5E-11 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 N186_00545 8bf82fbdb875d798c7d930f8d3173d2a 802 SMART SM00831 12 83 1.4E-13 T 31-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 N186_02390 6e981625576910f1066d7ed7e8c1f7ec 95 Gene3D G3DSA:3.90.940.10 13 93 7.4E-29 T 31-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02390 6e981625576910f1066d7ed7e8c1f7ec 95 Pfam PF01192 RNA polymerase Rpb6 19 71 3.0E-11 T 31-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02390 6e981625576910f1066d7ed7e8c1f7ec 95 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 21 77 18.582 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02390 6e981625576910f1066d7ed7e8c1f7ec 95 SUPERFAMILY SSF63562 15 91 2.3E-24 T 31-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02390 6e981625576910f1066d7ed7e8c1f7ec 95 PIRSF PIRSF000778 3 93 1.1E-28 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02390 6e981625576910f1066d7ed7e8c1f7ec 95 SMART SM01409 17 71 0.0047 T 31-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_08240 079953a10e13a9c12d0bd23a268eb954 359 Gene3D G3DSA:3.40.50.720 129 298 1.3E-116 T 31-10-2018 N186_08240 079953a10e13a9c12d0bd23a268eb954 359 Gene3D G3DSA:3.30.1780.10 20 336 1.3E-116 T 31-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 N186_08240 079953a10e13a9c12d0bd23a268eb954 359 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 16 315 9.8E-98 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 N186_08240 079953a10e13a9c12d0bd23a268eb954 359 PIRSF PIRSF001439 26 326 1.8E-69 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 N186_08240 079953a10e13a9c12d0bd23a268eb954 359 SUPERFAMILY SSF51735 2 339 8.02E-95 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_07515 4eda70210c325d772b95b482393a643e 271 Gene3D G3DSA:3.20.20.70 7 271 1.8E-79 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_07515 4eda70210c325d772b95b482393a643e 271 SMART SM01133 21 242 3.8E-43 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_07515 4eda70210c325d772b95b482393a643e 271 Pfam PF01791 DeoC/LacD family aldolase 22 242 4.4E-35 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_07515 4eda70210c325d772b95b482393a643e 271 PIRSF PIRSF038992 5 271 2.7E-80 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_07515 4eda70210c325d772b95b482393a643e 271 SUPERFAMILY SSF51569 7 258 2.34E-69 T 31-10-2018 N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 Gene3D G3DSA:1.10.10.10 306 406 3.2E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 SUPERFAMILY SSF46785 299 404 1.9E-27 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 Hamap MF_01407 ORC1-type DNA replication protein. 21 397 31.306 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 Pfam PF13401 AAA domain 68 190 1.2E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 Gene3D G3DSA:1.10.8.60 32 297 4.9E-103 T 31-10-2018 N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 Pfam PF09079 CDC6, C terminal winged helix domain 314 395 3.2E-20 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 28 385 2.7E-128 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 SMART SM01074 314 397 1.5E-31 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 SMART SM00382 66 220 1.9E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 Gene3D G3DSA:3.40.50.300 44 218 4.9E-103 T 31-10-2018 N186_04180 2bb48736dbbf78388fc6476c5a1fdaba 410 SUPERFAMILY SSF52540 29 294 1.97E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05160 48e422eded768d2fe2c5c71cae92ddb7 315 SUPERFAMILY SSF89447 13 56 1.01E-6 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_05160 48e422eded768d2fe2c5c71cae92ddb7 315 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 13 52 2.5E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_05160 48e422eded768d2fe2c5c71cae92ddb7 315 SUPERFAMILY SSF109755 131 266 3.01E-12 T 31-10-2018 N186_05160 48e422eded768d2fe2c5c71cae92ddb7 315 SMART SM00966 9 54 6.1E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_05160 48e422eded768d2fe2c5c71cae92ddb7 315 Gene3D G3DSA:1.20.58.220 135 242 2.0E-9 T 31-10-2018 IPR038078 PhoU-like domain superfamily N186_05160 48e422eded768d2fe2c5c71cae92ddb7 315 Pfam PF01895 PhoU domain 141 232 2.1E-9 T 31-10-2018 IPR026022 PhoU domain N186_06840 26b23d8f87e4b46159797932be3d0d04 384 SUPERFAMILY SSF54373 219 308 2.49E-5 T 31-10-2018 N186_06840 26b23d8f87e4b46159797932be3d0d04 384 Gene3D G3DSA:3.50.50.60 5 356 4.1E-69 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_06840 26b23d8f87e4b46159797932be3d0d04 384 Pfam PF01266 FAD dependent oxidoreductase 4 357 1.2E-55 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 N186_06840 26b23d8f87e4b46159797932be3d0d04 384 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 337 349 2.5E-11 T 31-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 N186_06840 26b23d8f87e4b46159797932be3d0d04 384 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 32 44 2.5E-11 T 31-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 N186_06840 26b23d8f87e4b46159797932be3d0d04 384 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 3 15 2.5E-11 T 31-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 N186_06840 26b23d8f87e4b46159797932be3d0d04 384 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 16 26 2.5E-11 T 31-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 N186_06840 26b23d8f87e4b46159797932be3d0d04 384 Gene3D G3DSA:3.30.9.10 79 309 4.1E-69 T 31-10-2018 N186_06840 26b23d8f87e4b46159797932be3d0d04 384 SUPERFAMILY SSF51905 3 364 8.2E-51 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_05550 415b448c53dfe247ad644a3479169754 575 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 108 417 6.2E-80 T 31-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 N186_05550 415b448c53dfe247ad644a3479169754 575 PRINTS PR00987 Glutamyl-tRNA synthetase signature 111 123 1.4E-17 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 N186_05550 415b448c53dfe247ad644a3479169754 575 PRINTS PR00987 Glutamyl-tRNA synthetase signature 141 154 1.4E-17 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 N186_05550 415b448c53dfe247ad644a3479169754 575 PRINTS PR00987 Glutamyl-tRNA synthetase signature 291 301 1.4E-17 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 N186_05550 415b448c53dfe247ad644a3479169754 575 PRINTS PR00987 Glutamyl-tRNA synthetase signature 307 315 1.4E-17 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 N186_05550 415b448c53dfe247ad644a3479169754 575 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 15 573 34.211 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 N186_05550 415b448c53dfe247ad644a3479169754 575 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 420 565 6.2E-22 T 31-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_05550 415b448c53dfe247ad644a3479169754 575 Gene3D G3DSA:2.40.240.100 420 574 6.2E-36 T 31-10-2018 N186_05550 415b448c53dfe247ad644a3479169754 575 SUPERFAMILY SSF52374 108 426 1.66E-88 T 31-10-2018 N186_05550 415b448c53dfe247ad644a3479169754 575 SUPERFAMILY SSF50715 420 566 3.56E-21 T 31-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_05550 415b448c53dfe247ad644a3479169754 575 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 12 574 1.3E-165 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 N186_05550 415b448c53dfe247ad644a3479169754 575 Gene3D G3DSA:2.40.240.10 429 520 6.2E-36 T 31-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_05550 415b448c53dfe247ad644a3479169754 575 Gene3D G3DSA:3.40.50.620 101 419 5.9E-109 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_03215 1ab4c875d35872e1b9feb2d48c67f190 98 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_03215 1ab4c875d35872e1b9feb2d48c67f190 98 Pfam PF14697 4Fe-4S dicluster domain 41 94 1.3E-11 T 31-10-2018 N186_03215 1ab4c875d35872e1b9feb2d48c67f190 98 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 21 98 1.0E-34 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 N186_03215 1ab4c875d35872e1b9feb2d48c67f190 98 SUPERFAMILY SSF54862 24 95 2.46E-22 T 31-10-2018 N186_03215 1ab4c875d35872e1b9feb2d48c67f190 98 Gene3D G3DSA:3.30.70.20 16 65 1.2E-5 T 31-10-2018 N186_03215 1ab4c875d35872e1b9feb2d48c67f190 98 Gene3D G3DSA:3.30.70.20 66 98 4.5E-9 T 31-10-2018 N186_07785 c22952716d9b91a0c106ccf65ba8704c 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 259 6.1E-18 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_07785 c22952716d9b91a0c106ccf65ba8704c 269 Gene3D G3DSA:1.10.3720.10 1 257 1.7E-49 T 31-10-2018 IPR035906 MetI-like superfamily N186_07785 c22952716d9b91a0c106ccf65ba8704c 269 SUPERFAMILY SSF161098 2 260 5.42E-53 T 31-10-2018 IPR035906 MetI-like superfamily N186_03820 615c503995747dfa20d9f89f91c518b6 741 SUPERFAMILY SSF52540 206 407 2.84E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03820 615c503995747dfa20d9f89f91c518b6 741 Pfam PF00271 Helicase conserved C-terminal domain 248 390 2.2E-9 T 31-10-2018 IPR001650 Helicase, C-terminal N186_03820 615c503995747dfa20d9f89f91c518b6 741 Gene3D G3DSA:1.10.3380.30 429 655 2.2E-64 T 31-10-2018 N186_03820 615c503995747dfa20d9f89f91c518b6 741 SUPERFAMILY SSF158702 510 713 1.12E-59 T 31-10-2018 N186_03820 615c503995747dfa20d9f89f91c518b6 741 SMART SM00278 659 678 0.3 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 N186_03820 615c503995747dfa20d9f89f91c518b6 741 SMART SM00278 692 711 12.0 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 N186_03820 615c503995747dfa20d9f89f91c518b6 741 SUPERFAMILY SSF46785 423 509 7.34E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_03820 615c503995747dfa20d9f89f91c518b6 741 Pfam PF14520 Helix-hairpin-helix domain 660 713 2.4E-13 T 31-10-2018 N186_03820 615c503995747dfa20d9f89f91c518b6 741 Gene3D G3DSA:3.40.50.300 12 209 3.3E-63 T 31-10-2018 N186_03820 615c503995747dfa20d9f89f91c518b6 741 Pfam PF00270 DEAD/DEAH box helicase 33 189 2.9E-23 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 N186_03820 615c503995747dfa20d9f89f91c518b6 741 SUPERFAMILY SSF52540 8 199 9.46E-47 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03820 615c503995747dfa20d9f89f91c518b6 741 SMART SM00490 299 391 3.8E-20 T 31-10-2018 IPR001650 Helicase, C-terminal N186_03820 615c503995747dfa20d9f89f91c518b6 741 Gene3D G3DSA:3.40.50.300 210 417 8.6E-56 T 31-10-2018 N186_03820 615c503995747dfa20d9f89f91c518b6 741 SMART SM00487 26 218 4.9E-31 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain N186_03820 615c503995747dfa20d9f89f91c518b6 741 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 15 714 30.402 T 31-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 N186_03820 615c503995747dfa20d9f89f91c518b6 741 Gene3D G3DSA:1.10.150.20 657 712 3.2E-18 T 31-10-2018 N186_06375 aa522b85b2d40c0a05188da95396b86f 381 SUPERFAMILY SSF56796 12 379 1.83E-102 T 31-10-2018 N186_06375 aa522b85b2d40c0a05188da95396b86f 381 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 180 208 - T 31-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 N186_06375 aa522b85b2d40c0a05188da95396b86f 381 Pfam PF00465 Iron-containing alcohol dehydrogenase 17 371 1.2E-101 T 31-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 N186_06375 aa522b85b2d40c0a05188da95396b86f 381 Gene3D G3DSA:3.40.50.1970 2 191 5.0E-55 T 31-10-2018 N186_06375 aa522b85b2d40c0a05188da95396b86f 381 Gene3D G3DSA:1.20.1090.10 193 380 2.5E-48 T 31-10-2018 N186_01730 9a0c61a45b196223dca108552deb764b 156 Gene3D G3DSA:1.10.10.10 70 148 2.5E-25 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_01730 9a0c61a45b196223dca108552deb764b 156 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 72 146 4.7E-23 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 N186_01730 9a0c61a45b196223dca108552deb764b 156 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 72 147 8.1E-22 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 N186_01730 9a0c61a45b196223dca108552deb764b 156 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 118 124 - T 31-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 N186_01730 9a0c61a45b196223dca108552deb764b 156 SUPERFAMILY SSF46767 72 146 1.7E-22 T 31-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 N186_09010 4ce02c36f700ae8c4d3c6d0ac658ecc8 128 Gene3D G3DSA:1.20.120.330 2 127 3.1E-23 T 31-10-2018 N186_09010 4ce02c36f700ae8c4d3c6d0ac658ecc8 128 SMART SM00748 10 120 9.8E-21 T 31-10-2018 IPR007842 HEPN domain N186_09010 4ce02c36f700ae8c4d3c6d0ac658ecc8 128 SUPERFAMILY SSF81593 9 122 9.81E-20 T 31-10-2018 N186_09010 4ce02c36f700ae8c4d3c6d0ac658ecc8 128 Pfam PF05168 HEPN domain 9 123 3.3E-24 T 31-10-2018 IPR007842 HEPN domain N186_09610 d76a3a41f6156e6e6e35f9c6c76936c8 234 SMART SM00382 26 231 1.5E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_09610 d76a3a41f6156e6e6e35f9c6c76936c8 234 Pfam PF00005 ABC transporter 18 163 6.7E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09610 d76a3a41f6156e6e6e35f9c6c76936c8 234 SUPERFAMILY SSF52540 2 222 3.19E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09610 d76a3a41f6156e6e6e35f9c6c76936c8 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_09610 d76a3a41f6156e6e6e35f9c6c76936c8 234 Gene3D G3DSA:3.40.50.300 1 233 1.0E-62 T 31-10-2018 N186_09040 7f52e7ea8de39471b0c205be5bf73621 440 Gene3D G3DSA:2.30.40.10 11 417 1.4E-113 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 N186_09040 7f52e7ea8de39471b0c205be5bf73621 440 SUPERFAMILY SSF51556 61 362 1.11E-76 T 31-10-2018 IPR032466 Metal-dependent hydrolase N186_09040 7f52e7ea8de39471b0c205be5bf73621 440 Pfam PF01979 Amidohydrolase family 59 410 1.5E-57 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 N186_09040 7f52e7ea8de39471b0c205be5bf73621 440 SUPERFAMILY SSF51338 1 430 8.36E-25 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 N186_09040 7f52e7ea8de39471b0c205be5bf73621 440 Gene3D G3DSA:3.20.20.140 63 360 1.4E-113 T 31-10-2018 N186_02075 f8a1b714073c582c9422abe256954c96 70 SUPERFAMILY SSF46785 15 67 6.45E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_02075 f8a1b714073c582c9422abe256954c96 70 Gene3D G3DSA:1.10.10.10 1 69 2.4E-30 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_02075 f8a1b714073c582c9422abe256954c96 70 Pfam PF04703 FaeA-like protein 13 67 3.3E-6 T 31-10-2018 IPR006793 FaeA-like protein GO:0006355|GO:0009289 N186_03905 c8b0ca8b36a313b5e4bdfd4fb6486acd 796 Gene3D G3DSA:3.40.50.300 552 795 2.6E-20 T 31-10-2018 N186_03905 c8b0ca8b36a313b5e4bdfd4fb6486acd 796 Gene3D G3DSA:3.40.50.300 3 309 2.6E-33 T 31-10-2018 N186_03905 c8b0ca8b36a313b5e4bdfd4fb6486acd 796 Pfam PF13476 AAA domain 8 251 5.2E-16 T 31-10-2018 IPR038729 Rad50/SbcC-type AAA domain N186_03905 c8b0ca8b36a313b5e4bdfd4fb6486acd 796 SUPERFAMILY SSF52540 7 781 1.13E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03905 c8b0ca8b36a313b5e4bdfd4fb6486acd 796 SUPERFAMILY SSF75712 373 477 1.44E-7 T 31-10-2018 N186_03905 c8b0ca8b36a313b5e4bdfd4fb6486acd 796 SUPERFAMILY SSF52540 5 279 5.84E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07010 f8eb974e91d68b24e1a8a9d3236e7139 224 TIGRFAM TIGR00277 HDIG: HDIG domain 36 103 2.7E-10 T 31-10-2018 IPR006675 HDIG domain N186_07010 f8eb974e91d68b24e1a8a9d3236e7139 224 Pfam PF01966 HD domain 36 140 1.9E-16 T 31-10-2018 IPR006674 HD domain N186_07010 f8eb974e91d68b24e1a8a9d3236e7139 224 SUPERFAMILY SSF109604 20 222 1.48E-64 T 31-10-2018 N186_07010 f8eb974e91d68b24e1a8a9d3236e7139 224 SMART SM00471 31 150 1.4E-11 T 31-10-2018 IPR003607 HD/PDEase domain N186_07010 f8eb974e91d68b24e1a8a9d3236e7139 224 Gene3D G3DSA:1.10.3210.50 12 223 3.9E-74 T 31-10-2018 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 SMART SM00248 134 163 4.9E-5 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 SMART SM00248 68 97 0.019 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 SMART SM00248 2 31 240.0 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 SMART SM00248 101 130 4.1E-6 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 SMART SM00248 167 197 2.0 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 SMART SM00248 35 64 3.0E-7 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 Gene3D G3DSA:1.25.40.960 139 191 4.3E-14 T 31-10-2018 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 PRINTS PR01415 Ankyrin repeat signature 36 51 6.4E-7 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 PRINTS PR01415 Ankyrin repeat signature 117 131 6.4E-7 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 Pfam PF12796 Ankyrin repeats (3 copies) 101 165 8.6E-14 T 31-10-2018 IPR020683 Ankyrin repeat-containing domain N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 Pfam PF13857 Ankyrin repeats (many copies) 25 75 2.0E-10 T 31-10-2018 N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 SUPERFAMILY SSF48403 7 192 9.73E-62 T 31-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily N186_05570 76c05139bb527738cf8c5eadec85b6fb 290 Gene3D G3DSA:1.25.40.20 1 138 1.7E-49 T 31-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily N186_05775 58f4ac454f21544f90cdadf4f21a526d 535 SUPERFAMILY SSF53067 6 253 1.95E-79 T 31-10-2018 N186_05775 58f4ac454f21544f90cdadf4f21a526d 535 Gene3D G3DSA:3.30.420.40 254 516 3.1E-74 T 31-10-2018 N186_05775 58f4ac454f21544f90cdadf4f21a526d 535 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 251 3.3E-73 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 N186_05775 58f4ac454f21544f90cdadf4f21a526d 535 SUPERFAMILY SSF53067 253 505 6.01E-59 T 31-10-2018 N186_05775 58f4ac454f21544f90cdadf4f21a526d 535 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 454 1.8E-34 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 N186_05775 58f4ac454f21544f90cdadf4f21a526d 535 Gene3D G3DSA:3.30.420.40 2 252 3.8E-87 T 31-10-2018 N186_05775 58f4ac454f21544f90cdadf4f21a526d 535 PIRSF PIRSF000538 3 510 8.5E-150 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 N186_05775 58f4ac454f21544f90cdadf4f21a526d 535 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 369 389 - T 31-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 N186_06660 cd8cc383da81bfd6411a8ba5ae9cfaa9 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 31-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site N186_06660 cd8cc383da81bfd6411a8ba5ae9cfaa9 90 SUPERFAMILY SSF55594 1 82 1.83E-25 T 31-10-2018 IPR035895 HPr-like superfamily N186_06660 cd8cc383da81bfd6411a8ba5ae9cfaa9 90 Gene3D G3DSA:3.30.1340.10 1 85 6.1E-31 T 31-10-2018 IPR035895 HPr-like superfamily N186_06660 cd8cc383da81bfd6411a8ba5ae9cfaa9 90 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.4E-17 T 31-10-2018 IPR000032 Phosphocarrier protein HPr-like N186_06660 cd8cc383da81bfd6411a8ba5ae9cfaa9 90 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.4E-17 T 31-10-2018 IPR000032 Phosphocarrier protein HPr-like N186_06660 cd8cc383da81bfd6411a8ba5ae9cfaa9 90 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.4E-17 T 31-10-2018 IPR000032 Phosphocarrier protein HPr-like N186_06660 cd8cc383da81bfd6411a8ba5ae9cfaa9 90 Pfam PF00381 PTS HPr component phosphorylation site 4 81 1.8E-28 T 31-10-2018 IPR000032 Phosphocarrier protein HPr-like N186_06660 cd8cc383da81bfd6411a8ba5ae9cfaa9 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 8.9E-27 T 31-10-2018 IPR000032 Phosphocarrier protein HPr-like N186_01065 9be3b376fdcfca09196584a4060ee2e9 463 SUPERFAMILY SSF111283 2 462 2.49E-110 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 N186_01065 9be3b376fdcfca09196584a4060ee2e9 463 Pfam PF01523 Putative modulator of DNA gyrase 20 314 8.3E-59 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 N186_01065 9be3b376fdcfca09196584a4060ee2e9 463 Gene3D G3DSA:3.30.2290.10 1 221 3.6E-24 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal N186_01065 9be3b376fdcfca09196584a4060ee2e9 463 PIRSF PIRSF004919 1 463 1.6E-156 T 31-10-2018 IPR025502 TldD N186_04235 2606f0ec00aae31fe8377c87d7f1c5fa 97 Gene3D G3DSA:3.30.1740.20 1 93 7.0E-23 T 31-10-2018 IPR038551 Ribosomal protein S26e superfamily N186_04235 2606f0ec00aae31fe8377c87d7f1c5fa 97 Pfam PF01283 Ribosomal protein S26e 1 92 2.0E-22 T 31-10-2018 IPR000892 Ribosomal protein S26e GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_05215 d3771750ccda2247dd5bf185ea83b49b 279 Gene3D G3DSA:1.10.3720.10 63 278 9.5E-26 T 31-10-2018 IPR035906 MetI-like superfamily N186_05215 d3771750ccda2247dd5bf185ea83b49b 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 270 7.1E-14 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_05215 d3771750ccda2247dd5bf185ea83b49b 279 SUPERFAMILY SSF161098 23 269 3.64E-28 T 31-10-2018 IPR035906 MetI-like superfamily N186_04895 690e7a716e44e0a8491b0a7260139959 432 Hamap MF_00900 GTPase HflX [hflX]. 27 392 38.955 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 N186_04895 690e7a716e44e0a8491b0a7260139959 432 Pfam PF01926 50S ribosome-binding GTPase 199 298 1.5E-15 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_04895 690e7a716e44e0a8491b0a7260139959 432 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 198 359 1.2E-11 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 N186_04895 690e7a716e44e0a8491b0a7260139959 432 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 26 362 5.3E-84 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 N186_04895 690e7a716e44e0a8491b0a7260139959 432 Gene3D G3DSA:3.40.50.11060 24 139 1.2E-29 T 31-10-2018 N186_04895 690e7a716e44e0a8491b0a7260139959 432 Pfam PF13167 GTP-binding GTPase N-terminal 28 112 1.8E-26 T 31-10-2018 IPR025121 GTPase HflX, N-terminal N186_04895 690e7a716e44e0a8491b0a7260139959 432 PIRSF PIRSF006809 2 424 1.8E-100 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 N186_04895 690e7a716e44e0a8491b0a7260139959 432 Pfam PF16360 GTP-binding GTPase Middle Region 114 191 2.1E-11 T 31-10-2018 IPR032305 GTP-binding protein, middle domain N186_04895 690e7a716e44e0a8491b0a7260139959 432 SUPERFAMILY SSF52540 196 365 9.15E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04895 690e7a716e44e0a8491b0a7260139959 432 Gene3D G3DSA:3.40.50.300 197 370 1.9E-35 T 31-10-2018 N186_07790 834c165b28c802e3c16fd32c197f9fe3 363 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_07790 834c165b28c802e3c16fd32c197f9fe3 363 Gene3D G3DSA:2.40.50.100 249 354 2.4E-16 T 31-10-2018 N186_07790 834c165b28c802e3c16fd32c197f9fe3 363 Gene3D G3DSA:2.40.50.140 286 344 2.4E-16 T 31-10-2018 N186_07790 834c165b28c802e3c16fd32c197f9fe3 363 SMART SM00382 37 220 4.2E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_07790 834c165b28c802e3c16fd32c197f9fe3 363 Pfam PF00005 ABC transporter 28 170 2.4E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_07790 834c165b28c802e3c16fd32c197f9fe3 363 SUPERFAMILY SSF50331 245 358 2.92E-19 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal N186_07790 834c165b28c802e3c16fd32c197f9fe3 363 SUPERFAMILY SSF52540 13 251 5.46E-92 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07790 834c165b28c802e3c16fd32c197f9fe3 363 Gene3D G3DSA:3.40.50.300 5 247 2.8E-80 T 31-10-2018 N186_07985 548c7bf12841b7608e51719580dfc25b 380 SUPERFAMILY SSF53448 3 237 2.87E-36 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_07985 548c7bf12841b7608e51719580dfc25b 380 Pfam PF00535 Glycosyl transferase family 2 10 170 1.1E-24 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 N186_07985 548c7bf12841b7608e51719580dfc25b 380 Gene3D G3DSA:3.90.550.10 1 228 3.6E-46 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_08805 5e50c5edb30b28e7f74e728ca60fe429 307 SMART SM00382 29 219 5.0E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_08805 5e50c5edb30b28e7f74e728ca60fe429 307 SUPERFAMILY SSF52540 3 221 1.81E-68 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08805 5e50c5edb30b28e7f74e728ca60fe429 307 Pfam PF00005 ABC transporter 21 164 1.5E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_08805 5e50c5edb30b28e7f74e728ca60fe429 307 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_08805 5e50c5edb30b28e7f74e728ca60fe429 307 Gene3D G3DSA:3.40.50.300 2 226 9.5E-72 T 31-10-2018 N186_07600 17ce84f843ae4ea650aa36d640cb0bdf 229 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 88 9.4E-6 T 31-10-2018 N186_07600 17ce84f843ae4ea650aa36d640cb0bdf 229 Pfam PF08282 haloacid dehalogenase-like hydrolase 143 218 3.3E-15 T 31-10-2018 N186_07600 17ce84f843ae4ea650aa36d640cb0bdf 229 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 5 218 5.5E-38 T 31-10-2018 N186_07600 17ce84f843ae4ea650aa36d640cb0bdf 229 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 193 4.9E-14 T 31-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 N186_07600 17ce84f843ae4ea650aa36d640cb0bdf 229 Gene3D G3DSA:3.40.50.1000 4 222 9.7E-54 T 31-10-2018 IPR023214 HAD superfamily N186_07600 17ce84f843ae4ea650aa36d640cb0bdf 229 Gene3D G3DSA:3.90.1070.10 81 152 9.7E-54 T 31-10-2018 N186_07600 17ce84f843ae4ea650aa36d640cb0bdf 229 SUPERFAMILY SSF56784 1 228 1.49E-39 T 31-10-2018 IPR036412 HAD-like superfamily N186_07600 17ce84f843ae4ea650aa36d640cb0bdf 229 Hamap MF_01419 Phosphoglycolate phosphatase. 2 228 24.277 T 31-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 N186_07600 17ce84f843ae4ea650aa36d640cb0bdf 229 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 4 222 6.0E-49 T 31-10-2018 N186_00300 73315fa8439f853effec19d6a3c0cf25 119 Gene3D G3DSA:3.40.50.1010 1 119 1.1E-5 T 31-10-2018 N186_00300 73315fa8439f853effec19d6a3c0cf25 119 Pfam PF01850 PIN domain 3 110 4.5E-11 T 31-10-2018 IPR002716 PIN domain N186_00300 73315fa8439f853effec19d6a3c0cf25 119 SUPERFAMILY SSF88723 2 118 9.81E-11 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_03395 60e2c2238926bbf8d1b8868e968e0bc7 189 Gene3D G3DSA:3.30.1140.32 72 185 3.1E-38 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03395 60e2c2238926bbf8d1b8868e968e0bc7 189 Pfam PF00189 Ribosomal protein S3, C-terminal domain 84 167 6.3E-24 T 31-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03395 60e2c2238926bbf8d1b8868e968e0bc7 189 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 1 179 1.9E-66 T 31-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03395 60e2c2238926bbf8d1b8868e968e0bc7 189 SMART SM00322 23 89 2.4E-5 T 31-10-2018 IPR004087 K Homology domain GO:0003676 N186_03395 60e2c2238926bbf8d1b8868e968e0bc7 189 SUPERFAMILY SSF54821 72 170 4.05E-26 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03395 60e2c2238926bbf8d1b8868e968e0bc7 189 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 1 181 34.704 T 31-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 N186_03395 60e2c2238926bbf8d1b8868e968e0bc7 189 Gene3D G3DSA:3.30.300.20 1 70 9.9E-20 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta N186_03395 60e2c2238926bbf8d1b8868e968e0bc7 189 Pfam PF07650 KH domain 3 72 1.3E-9 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03395 60e2c2238926bbf8d1b8868e968e0bc7 189 SUPERFAMILY SSF54814 2 80 1.31E-19 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 N186_07450 0e39ffa4a98c9b0a2d0b1d2c02c59fe3 436 Gene3D G3DSA:3.40.190.10 35 433 4.2E-74 T 31-10-2018 N186_07450 0e39ffa4a98c9b0a2d0b1d2c02c59fe3 436 SUPERFAMILY SSF53850 44 430 3.85E-63 T 31-10-2018 N186_07450 0e39ffa4a98c9b0a2d0b1d2c02c59fe3 436 Pfam PF13416 Bacterial extracellular solute-binding protein 62 372 2.0E-34 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein N186_00465 c39b6b1984adfff3ecec8c0192266150 347 Gene3D G3DSA:3.90.180.10 21 333 9.6E-92 T 31-10-2018 N186_00465 c39b6b1984adfff3ecec8c0192266150 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 131 1.5E-32 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 N186_00465 c39b6b1984adfff3ecec8c0192266150 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 N186_00465 c39b6b1984adfff3ecec8c0192266150 347 Gene3D G3DSA:3.40.50.720 156 292 9.6E-92 T 31-10-2018 N186_00465 c39b6b1984adfff3ecec8c0192266150 347 SUPERFAMILY SSF51735 145 311 1.03E-30 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_00465 c39b6b1984adfff3ecec8c0192266150 347 SUPERFAMILY SSF50129 5 177 1.57E-50 T 31-10-2018 IPR011032 GroES-like superfamily N186_00465 c39b6b1984adfff3ecec8c0192266150 347 Pfam PF00107 Zinc-binding dehydrogenase 178 307 6.3E-20 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 N186_00465 c39b6b1984adfff3ecec8c0192266150 347 SMART SM00829 11 264 3.5E-5 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 N186_04560 3789119e5a42d8bf9cb7aba3680e793f 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 2 101 22.664 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04560 3789119e5a42d8bf9cb7aba3680e793f 102 Gene3D G3DSA:3.30.70.600 2 102 1.1E-30 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily N186_04560 3789119e5a42d8bf9cb7aba3680e793f 102 PRINTS PR00971 Ribosomal protein S10 family signature 39 54 1.1E-14 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04560 3789119e5a42d8bf9cb7aba3680e793f 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.1E-14 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04560 3789119e5a42d8bf9cb7aba3680e793f 102 PRINTS PR00971 Ribosomal protein S10 family signature 4 17 1.1E-14 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04560 3789119e5a42d8bf9cb7aba3680e793f 102 SUPERFAMILY SSF54999 4 100 3.66E-26 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily N186_04560 3789119e5a42d8bf9cb7aba3680e793f 102 SMART SM01403 6 100 2.6E-34 T 31-10-2018 IPR027486 Ribosomal protein S10 domain N186_04560 3789119e5a42d8bf9cb7aba3680e793f 102 Pfam PF00338 Ribosomal protein S10p/S20e 6 99 2.4E-24 T 31-10-2018 IPR027486 Ribosomal protein S10 domain N186_04560 3789119e5a42d8bf9cb7aba3680e793f 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 4 100 1.3E-41 T 31-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02205 a4131e35a868515d444f15a8210a01a1 158 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 24.762 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02205 a4131e35a868515d444f15a8210a01a1 158 Gene3D G3DSA:4.10.910.10 89 138 1.3E-19 T 31-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02205 a4131e35a868515d444f15a8210a01a1 158 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 147 4.9E-57 T 31-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02205 a4131e35a868515d444f15a8210a01a1 158 ProSitePatterns PS00646 Ribosomal protein S13 signature. 117 130 - T 31-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02205 a4131e35a868515d444f15a8210a01a1 158 SUPERFAMILY SSF46946 9 148 4.56E-34 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 N186_02205 a4131e35a868515d444f15a8210a01a1 158 Pfam PF00416 Ribosomal protein S13/S18 10 138 1.9E-37 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02205 a4131e35a868515d444f15a8210a01a1 158 PIRSF PIRSF002134 2 153 8.0E-41 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02205 a4131e35a868515d444f15a8210a01a1 158 Gene3D G3DSA:1.10.8.50 1 76 3.5E-19 T 31-10-2018 N186_01960 ba7e41c6ec52fa81cc252da467f3bde8 225 Pfam PF00687 Ribosomal protein L1p/L10e family 25 213 2.8E-40 T 31-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein N186_01960 ba7e41c6ec52fa81cc252da467f3bde8 225 SUPERFAMILY SSF56808 21 218 3.66E-55 T 31-10-2018 IPR023674 Ribosomal protein L1-like N186_01960 ba7e41c6ec52fa81cc252da467f3bde8 225 Gene3D G3DSA:3.30.190.20 24 214 3.5E-68 T 31-10-2018 N186_01960 ba7e41c6ec52fa81cc252da467f3bde8 225 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 8 219 34.824 T 31-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 N186_01960 ba7e41c6ec52fa81cc252da467f3bde8 225 Gene3D G3DSA:3.40.50.790 65 156 3.5E-68 T 31-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich N186_01960 ba7e41c6ec52fa81cc252da467f3bde8 225 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 140 - T 31-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01960 ba7e41c6ec52fa81cc252da467f3bde8 225 PIRSF PIRSF002155 7 221 1.4E-57 T 31-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05810 08572ad676310a2a16bcda3dac0c4fcd 210 Pfam PF04266 ASCH domain 28 120 8.9E-12 T 31-10-2018 IPR007374 ASCH domain N186_05810 08572ad676310a2a16bcda3dac0c4fcd 210 SUPERFAMILY SSF88697 25 121 5.47E-19 T 31-10-2018 IPR015947 PUA-like superfamily N186_05810 08572ad676310a2a16bcda3dac0c4fcd 210 SMART SM01022 28 126 9.1E-23 T 31-10-2018 IPR007374 ASCH domain N186_07425 3d5bf270630e2de8f99efcf41fd6bbe4 378 Gene3D G3DSA:3.40.50.620 8 222 4.1E-51 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_07425 3d5bf270630e2de8f99efcf41fd6bbe4 378 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 8 360 41.509 T 31-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 N186_07425 3d5bf270630e2de8f99efcf41fd6bbe4 378 SUPERFAMILY SSF52374 8 361 9.14E-57 T 31-10-2018 N186_07425 3d5bf270630e2de8f99efcf41fd6bbe4 378 Pfam PF00579 tRNA synthetases class I (W and Y) 36 353 8.3E-37 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_07425 3d5bf270630e2de8f99efcf41fd6bbe4 378 PIRSF PIRSF006588 4 377 1.9E-111 T 31-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 N186_07425 3d5bf270630e2de8f99efcf41fd6bbe4 378 Gene3D G3DSA:1.10.240.10 233 375 4.8E-42 T 31-10-2018 N186_06520 0fe17ecf2abfee068fc11997cdfc0def 332 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 37 1.7E-5 T 31-10-2018 N186_06520 0fe17ecf2abfee068fc11997cdfc0def 332 SUPERFAMILY SSF51905 4 272 1.18E-19 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_06520 0fe17ecf2abfee068fc11997cdfc0def 332 Gene3D G3DSA:3.50.50.60 4 322 1.3E-27 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 19 648 4.0E-263 T 31-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 Gene3D G3DSA:3.40.50.10890 397 582 1.9E-143 T 31-10-2018 N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 SMART SM00849 202 407 3.0E-25 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 Pfam PF10996 Beta-Casp domain 429 551 1.6E-19 T 31-10-2018 IPR022712 Beta-Casp domain N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 SMART SM01027 429 551 3.8E-48 T 31-10-2018 IPR022712 Beta-Casp domain N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 Gene3D G3DSA:3.30.300.20 79 146 1.6E-50 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 Gene3D G3DSA:3.30.300.230 23 180 1.6E-50 T 31-10-2018 N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 571 632 2.0E-14 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 Pfam PF00753 Metallo-beta-lactamase superfamily 201 372 2.0E-14 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 Pfam PF17214 KH domain 18 81 1.2E-21 T 31-10-2018 IPR033769 KH domain, archaeal N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 SUPERFAMILY SSF56281 190 648 3.14E-123 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_02550 e190e5c9f24661fe2a146ea49f97c076 649 Gene3D G3DSA:3.60.15.10 195 619 1.9E-143 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_03140 a3b9013e5202fbaabd65305288f66a05 340 SMART SM00475 21 328 2.8E-4 T 31-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 SMART SM00484 141 222 1.2E-22 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 3.4E-29 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 140 157 3.4E-29 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 76 95 3.4E-29 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 227 242 3.4E-29 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 161 181 3.4E-29 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 SUPERFAMILY SSF47807 222 333 4.78E-27 T 31-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily N186_03140 a3b9013e5202fbaabd65305288f66a05 340 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 340 109.146 T 31-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 SMART SM00485 1 102 3.9E-31 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 Pfam PF00752 XPG N-terminal domain 12 101 1.9E-16 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 339 2.6E-126 T 31-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 Gene3D G3DSA:3.40.50.1010 4 340 1.3E-91 T 31-10-2018 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 SMART SM00279 224 257 1.9E-13 T 31-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 Pfam PF00867 XPG I-region 141 237 1.5E-22 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 N186_03140 a3b9013e5202fbaabd65305288f66a05 340 SUPERFAMILY SSF88723 4 237 6.45E-58 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_00710 f4b58ef13b73acf6d29ab92035a08c96 146 Gene3D G3DSA:3.90.1530.10 5 102 4.0E-23 T 31-10-2018 N186_00710 f4b58ef13b73acf6d29ab92035a08c96 146 Pfam PF02195 ParB-like nuclease domain 12 82 8.6E-11 T 31-10-2018 IPR003115 ParB/Sulfiredoxin N186_00710 f4b58ef13b73acf6d29ab92035a08c96 146 SUPERFAMILY SSF110849 12 123 2.49E-27 T 31-10-2018 IPR036086 ParB/Sulfiredoxin superfamily N186_00710 f4b58ef13b73acf6d29ab92035a08c96 146 SMART SM00470 8 98 6.7E-7 T 31-10-2018 IPR003115 ParB/Sulfiredoxin N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 Pfam PF09261 Alpha mannosidase middle domain 523 600 4.5E-21 T 31-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 SUPERFAMILY SSF88713 259 522 1.16E-66 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 260 516 1.7E-68 T 31-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 SUPERFAMILY SSF88688 523 626 4.58E-23 T 31-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 628 1032 1.9E-52 T 31-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 SUPERFAMILY SSF74650 617 1034 1.57E-61 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 Gene3D G3DSA:3.20.110.10 254 464 3.0E-53 T 31-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 Gene3D G3DSA:1.20.1270.50 526 621 2.6E-22 T 31-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 SMART SM00872 523 600 2.0E-25 T 31-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 N186_07625 1dc27e8f60f2524159e0fd1ea2886904 1035 Gene3D G3DSA:2.70.98.30 757 927 1.0E-10 T 31-10-2018 N186_01810 b62c5357d01bb7a90caca948e9815ad5 339 SUPERFAMILY SSF101821 67 172 3.82E-23 T 31-10-2018 N186_01810 b62c5357d01bb7a90caca948e9815ad5 339 Pfam PF05343 M42 glutamyl aminopeptidase 44 329 7.2E-86 T 31-10-2018 IPR008007 Peptidase M42 N186_01810 b62c5357d01bb7a90caca948e9815ad5 339 PIRSF PIRSF001123 2 337 1.3E-99 T 31-10-2018 IPR008007 Peptidase M42 N186_01810 b62c5357d01bb7a90caca948e9815ad5 339 Gene3D G3DSA:3.40.630.10 6 329 1.4E-109 T 31-10-2018 N186_01810 b62c5357d01bb7a90caca948e9815ad5 339 SUPERFAMILY SSF53187 6 336 6.99E-60 T 31-10-2018 N186_01810 b62c5357d01bb7a90caca948e9815ad5 339 Gene3D G3DSA:2.40.30.40 66 156 1.4E-109 T 31-10-2018 IPR023367 Peptidase M42, domain 2 N186_03935 f325ce150e17f8d2950d66654d0661f4 96 SUPERFAMILY SSF82704 11 94 5.23E-24 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 N186_03935 f325ce150e17f8d2950d66654d0661f4 96 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 13 95 4.0E-24 T 31-10-2018 N186_03935 f325ce150e17f8d2950d66654d0661f4 96 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 9 94 1.2E-32 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 N186_03935 f325ce150e17f8d2950d66654d0661f4 96 Gene3D G3DSA:3.30.110.20 6 94 1.0E-31 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 N186_03935 f325ce150e17f8d2950d66654d0661f4 96 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 4 94 24.143 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 N186_03935 f325ce150e17f8d2950d66654d0661f4 96 Pfam PF01918 Alba 11 72 3.7E-20 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 N186_03935 f325ce150e17f8d2950d66654d0661f4 96 PIRSF PIRSF028732 5 95 3.3E-33 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 N186_02245 c08887acc6981c77771e8987999f2c1a 200 PIRSF PIRSF002122 3 200 1.5E-47 T 31-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 N186_02245 c08887acc6981c77771e8987999f2c1a 200 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 15 200 6.8E-87 T 31-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02245 c08887acc6981c77771e8987999f2c1a 200 SUPERFAMILY SSF47973 17 200 1.44E-63 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily N186_02245 c08887acc6981c77771e8987999f2c1a 200 ProSitePatterns PS00052 Ribosomal protein S7 signature. 66 92 - T 31-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02245 c08887acc6981c77771e8987999f2c1a 200 Gene3D G3DSA:1.10.455.10 5 200 2.7E-86 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily N186_02245 c08887acc6981c77771e8987999f2c1a 200 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 16 200 40.578 T 31-10-2018 IPR026018 Ribosomal protein S7, archaeal N186_02245 c08887acc6981c77771e8987999f2c1a 200 Pfam PF00177 Ribosomal protein S7p/S5e 58 200 4.0E-42 T 31-10-2018 IPR023798 Ribosomal protein S7 domain N186_07340 0d2128876b567faed0dfc7f302994940 85 Gene3D G3DSA:2.10.260.10 6 45 1.1E-7 T 31-10-2018 N186_07340 0d2128876b567faed0dfc7f302994940 85 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 47 3.1E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_07340 0d2128876b567faed0dfc7f302994940 85 SUPERFAMILY SSF89447 5 60 6.15E-10 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_07340 0d2128876b567faed0dfc7f302994940 85 SMART SM00966 9 52 2.1E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_07340 0d2128876b567faed0dfc7f302994940 85 Pfam PF02381 MraZ protein, putative antitoxin-like 9 59 4.2E-7 T 31-10-2018 IPR020603 MraZ domain N186_04735 7a78f46d7699732f0e386c23a2891087 721 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 8 719 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 N186_04735 7a78f46d7699732f0e386c23a2891087 721 ProSitePatterns PS00674 AAA-protein family signature. 594 612 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 N186_04735 7a78f46d7699732f0e386c23a2891087 721 Gene3D G3DSA:1.10.8.60 625 697 9.5E-113 T 31-10-2018 N186_04735 7a78f46d7699732f0e386c23a2891087 721 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 113 172 2.2E-14 T 31-10-2018 IPR004201 CDC48, domain 2 N186_04735 7a78f46d7699732f0e386c23a2891087 721 Gene3D G3DSA:3.40.50.300 451 711 9.5E-113 T 31-10-2018 N186_04735 7a78f46d7699732f0e386c23a2891087 721 Pfam PF09336 Vps4 C terminal oligomerisation domain 681 716 1.3E-6 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal N186_04735 7a78f46d7699732f0e386c23a2891087 721 Gene3D G3DSA:1.10.8.60 351 446 1.3E-35 T 31-10-2018 N186_04735 7a78f46d7699732f0e386c23a2891087 721 SUPERFAMILY SSF54585 94 185 3.6E-19 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily N186_04735 7a78f46d7699732f0e386c23a2891087 721 SMART SM00382 489 626 8.9E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04735 7a78f46d7699732f0e386c23a2891087 721 SMART SM00382 216 352 1.9E-23 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04735 7a78f46d7699732f0e386c23a2891087 721 SMART SM01072 110 173 4.6E-15 T 31-10-2018 IPR004201 CDC48, domain 2 N186_04735 7a78f46d7699732f0e386c23a2891087 721 SMART SM01073 9 93 3.5E-40 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain N186_04735 7a78f46d7699732f0e386c23a2891087 721 Gene3D G3DSA:3.10.330.10 94 174 2.7E-8 T 31-10-2018 N186_04735 7a78f46d7699732f0e386c23a2891087 721 SUPERFAMILY SSF52540 178 443 1.83E-75 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04735 7a78f46d7699732f0e386c23a2891087 721 SUPERFAMILY SSF52540 451 716 3.87E-81 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04735 7a78f46d7699732f0e386c23a2891087 721 ProSitePatterns PS00674 AAA-protein family signature. 320 338 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 N186_04735 7a78f46d7699732f0e386c23a2891087 721 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 220 349 2.7E-49 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 N186_04735 7a78f46d7699732f0e386c23a2891087 721 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 493 623 3.5E-49 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 N186_04735 7a78f46d7699732f0e386c23a2891087 721 Gene3D G3DSA:3.40.50.300 175 350 1.5E-71 T 31-10-2018 N186_04735 7a78f46d7699732f0e386c23a2891087 721 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 10 92 1.0E-35 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain N186_04735 7a78f46d7699732f0e386c23a2891087 721 SUPERFAMILY SSF50692 4 91 4.97E-31 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily N186_04735 7a78f46d7699732f0e386c23a2891087 721 Gene3D G3DSA:2.40.40.20 2 93 2.8E-37 T 31-10-2018 N186_04825 b15cba0901489ad1d8e0b70cbf553d5f 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 1 89 1.0E-20 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 N186_04825 b15cba0901489ad1d8e0b70cbf553d5f 91 SMART SM00888 3 89 1.9E-33 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 N186_04825 b15cba0901489ad1d8e0b70cbf553d5f 91 SUPERFAMILY SSF54984 1 89 1.83E-21 T 31-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 N186_04825 b15cba0901489ad1d8e0b70cbf553d5f 91 Gene3D G3DSA:3.30.70.60 1 90 3.1E-27 T 31-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 N186_04825 b15cba0901489ad1d8e0b70cbf553d5f 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 37.306 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 N186_04825 b15cba0901489ad1d8e0b70cbf553d5f 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 6 89 1.3E-16 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 N186_04825 b15cba0901489ad1d8e0b70cbf553d5f 91 PIRSF PIRSF006521 1 89 4.4E-33 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 N186_04940 8ee0628471a21167ba653a40ee391cc9 341 SUPERFAMILY SSF55347 159 301 3.92E-9 T 31-10-2018 N186_04940 8ee0628471a21167ba653a40ee391cc9 341 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 123 6.3E-22 T 31-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 N186_04940 8ee0628471a21167ba653a40ee391cc9 341 Gene3D G3DSA:3.30.360.10 124 316 1.9E-50 T 31-10-2018 N186_04940 8ee0628471a21167ba653a40ee391cc9 341 Gene3D G3DSA:3.40.50.720 4 305 1.9E-50 T 31-10-2018 N186_04940 8ee0628471a21167ba653a40ee391cc9 341 SUPERFAMILY SSF51735 3 181 2.07E-31 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_04070 ce0d3690338210c24127d1b4b97cbdb2 204 Gene3D G3DSA:3.40.50.300 23 158 1.0E-17 T 31-10-2018 N186_04070 ce0d3690338210c24127d1b4b97cbdb2 204 SUPERFAMILY SSF52540 15 148 2.23E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01735 c56dc07fe979f087336a406a8a299664 296 SUPERFAMILY SSF52540 4 275 1.1E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01735 c56dc07fe979f087336a406a8a299664 296 Pfam PF02374 Anion-transporting ATPase 5 257 7.3E-26 T 31-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 N186_01735 c56dc07fe979f087336a406a8a299664 296 Gene3D G3DSA:3.40.50.300 3 287 3.5E-39 T 31-10-2018 N186_07950 f6fa80f30e49bcbcf902aafd5642e83f 176 Gene3D G3DSA:2.60.120.10 2 153 1.7E-35 T 31-10-2018 IPR014710 RmlC-like jelly roll fold N186_07950 f6fa80f30e49bcbcf902aafd5642e83f 176 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 5 150 5.0E-9 T 31-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 N186_07950 f6fa80f30e49bcbcf902aafd5642e83f 176 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 9 150 1.8E-12 T 31-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 N186_07950 f6fa80f30e49bcbcf902aafd5642e83f 176 SUPERFAMILY SSF51182 6 150 4.68E-31 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily N186_02565 32a91f3b5532ed86dc27b87f1c523220 173 PIRSF PIRSF006443 1 173 1.1E-50 T 31-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 N186_02565 32a91f3b5532ed86dc27b87f1c523220 173 SMART SM00852 15 166 6.8E-24 T 31-10-2018 IPR001453 MoaB/Mog domain N186_02565 32a91f3b5532ed86dc27b87f1c523220 173 Pfam PF00994 Probable molybdopterin binding domain 16 162 4.2E-27 T 31-10-2018 IPR001453 MoaB/Mog domain N186_02565 32a91f3b5532ed86dc27b87f1c523220 173 SUPERFAMILY SSF53218 5 170 1.83E-35 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily N186_02565 32a91f3b5532ed86dc27b87f1c523220 173 Gene3D G3DSA:3.40.980.10 1 172 3.4E-39 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily N186_02565 32a91f3b5532ed86dc27b87f1c523220 173 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 12 161 1.6E-30 T 31-10-2018 IPR001453 MoaB/Mog domain N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 SUPERFAMILY SSF55681 61 254 3.6E-58 T 31-10-2018 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 Gene3D G3DSA:3.10.310.40 809 905 7.0E-9 T 31-10-2018 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 Gene3D G3DSA:3.30.980.10 594 735 1.3E-49 T 31-10-2018 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 7 901 0.0 T 31-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 SUPERFAMILY SSF50447 503 588 1.91E-14 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 SMART SM00863 693 736 1.8E-16 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 SUPERFAMILY SSF55186 594 743 1.96E-46 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 SUPERFAMILY SSF101353 300 492 1.31E-53 T 31-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 Pfam PF01411 tRNA synthetases class II (A) 63 593 2.6E-130 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 Gene3D G3DSA:2.40.30.130 495 590 7.1E-26 T 31-10-2018 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 Gene3D G3DSA:3.30.54.20 662 717 1.3E-49 T 31-10-2018 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 6 901 22.327 T 31-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 63 884 6.4E-208 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 Gene3D G3DSA:3.30.930.10 1 250 3.3E-100 T 31-10-2018 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 Pfam PF02272 DHHA1 domain 774 896 9.7E-7 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 PRINTS PR00980 Alanyl-tRNA synthetase signature 235 248 8.5E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 PRINTS PR00980 Alanyl-tRNA synthetase signature 129 140 8.5E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 PRINTS PR00980 Alanyl-tRNA synthetase signature 350 363 8.5E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 PRINTS PR00980 Alanyl-tRNA synthetase signature 326 342 8.5E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 PRINTS PR00980 Alanyl-tRNA synthetase signature 208 219 8.5E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 N186_01950 17d40c04fd21d4a59ffdb83f6ca19303 908 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 693 735 2.8E-13 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 N186_00285 e2ce7daa81a57b21cefb0b353c04c9d9 285 SUPERFAMILY SSF48150 100 218 1.73E-15 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 N186_00285 e2ce7daa81a57b21cefb0b353c04c9d9 285 SMART SM00478 106 255 0.0044 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 N186_00285 e2ce7daa81a57b21cefb0b353c04c9d9 285 Gene3D G3DSA:1.10.340.30 98 194 7.6E-8 T 31-10-2018 N186_00285 e2ce7daa81a57b21cefb0b353c04c9d9 285 Gene3D G3DSA:1.10.1670.10 195 216 7.6E-8 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 N186_05565 304b1488fdef03f9e51e9e9013f497f5 519 Pfam PF00437 Type II/IV secretion system protein 128 374 1.1E-51 T 31-10-2018 IPR001482 Type II/IV secretion system protein N186_05565 304b1488fdef03f9e51e9e9013f497f5 519 SUPERFAMILY SSF52540 107 421 3.6E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05565 304b1488fdef03f9e51e9e9013f497f5 519 Gene3D G3DSA:3.40.50.300 225 504 2.6E-97 T 31-10-2018 N186_05565 304b1488fdef03f9e51e9e9013f497f5 519 Gene3D G3DSA:3.30.450.380 4 223 2.5E-67 T 31-10-2018 N186_02940 57cb9abd5ca8a06f03a3bd963fc7f171 320 Gene3D G3DSA:3.40.50.10470 97 284 2.6E-60 T 31-10-2018 N186_02940 57cb9abd5ca8a06f03a3bd963fc7f171 320 Gene3D G3DSA:1.20.120.420 43 96 2.6E-60 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 N186_02940 57cb9abd5ca8a06f03a3bd963fc7f171 320 Pfam PF01008 Initiation factor 2 subunit family 18 284 5.9E-60 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 N186_02940 57cb9abd5ca8a06f03a3bd963fc7f171 320 SUPERFAMILY SSF100950 7 296 4.4E-66 T 31-10-2018 IPR037171 NagB/RpiA transferase-like N186_02345 a43212d15bf5d94fecbd85050374d3a8 80 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 11 78 2.0E-16 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02345 a43212d15bf5d94fecbd85050374d3a8 80 SUPERFAMILY SSF55287 5 78 1.28E-25 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02345 a43212d15bf5d94fecbd85050374d3a8 80 Gene3D G3DSA:3.90.940.20 1 79 7.8E-31 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02345 a43212d15bf5d94fecbd85050374d3a8 80 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 5 77 8.9E-31 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02345 a43212d15bf5d94fecbd85050374d3a8 80 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 5 78 23.413 T 31-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02345 a43212d15bf5d94fecbd85050374d3a8 80 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 10 23 - T 31-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_03495 f407b0999e2ca8a1ca675bbdb262e2d1 183 Hamap MF_00039 Putative adenylate kinase. 1 167 22.186 T 31-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_03495 f407b0999e2ca8a1ca675bbdb262e2d1 183 Pfam PF13238 AAA domain 3 122 1.2E-22 T 31-10-2018 N186_03495 f407b0999e2ca8a1ca675bbdb262e2d1 183 Gene3D G3DSA:3.40.50.300 1 181 1.8E-36 T 31-10-2018 N186_03495 f407b0999e2ca8a1ca675bbdb262e2d1 183 SUPERFAMILY SSF52540 3 160 1.39E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02500 2f2f6cc055ed5b647caf87548bbd8faa 315 SUPERFAMILY SSF52540 1 208 1.69E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02500 2f2f6cc055ed5b647caf87548bbd8faa 315 Pfam PF13614 AAA domain 5 192 2.0E-18 T 31-10-2018 IPR025669 AAA domain N186_02500 2f2f6cc055ed5b647caf87548bbd8faa 315 Gene3D G3DSA:3.40.50.300 6 262 8.6E-32 T 31-10-2018 N186_03865 f16f4d43763c3b78f23cea8aec4022a0 244 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 5 241 56.65 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 N186_03865 f16f4d43763c3b78f23cea8aec4022a0 244 SUPERFAMILY SSF54211 10 180 4.76E-45 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_03865 f16f4d43763c3b78f23cea8aec4022a0 244 SUPERFAMILY SSF55666 154 239 5.24E-23 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 N186_03865 f16f4d43763c3b78f23cea8aec4022a0 244 Gene3D G3DSA:3.30.230.70 5 242 1.2E-75 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 N186_03865 f16f4d43763c3b78f23cea8aec4022a0 244 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 237 7.4E-107 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 N186_03865 f16f4d43763c3b78f23cea8aec4022a0 244 Pfam PF03725 3' exoribonuclease family, domain 2 156 221 4.0E-15 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 N186_03865 f16f4d43763c3b78f23cea8aec4022a0 244 Pfam PF01138 3' exoribonuclease family, domain 1 24 152 1.2E-33 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 N186_06045 da97cb006c00c33afb8dc482a071d875 444 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 61 189 5.6E-54 T 31-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 N186_06045 da97cb006c00c33afb8dc482a071d875 444 SUPERFAMILY SSF53223 26 209 1.44E-66 T 31-10-2018 N186_06045 da97cb006c00c33afb8dc482a071d875 444 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 368 379 5.9E-30 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 N186_06045 da97cb006c00c33afb8dc482a071d875 444 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 118 132 5.9E-30 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 N186_06045 da97cb006c00c33afb8dc482a071d875 444 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 198 220 5.9E-30 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 N186_06045 da97cb006c00c33afb8dc482a071d875 444 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 240 260 5.9E-30 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 N186_06045 da97cb006c00c33afb8dc482a071d875 444 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 126 139 - T 31-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 N186_06045 da97cb006c00c33afb8dc482a071d875 444 Gene3D G3DSA:3.40.50.10860 63 206 1.7E-60 T 31-10-2018 N186_06045 da97cb006c00c33afb8dc482a071d875 444 SUPERFAMILY SSF51735 207 443 1.43E-74 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_06045 da97cb006c00c33afb8dc482a071d875 444 SMART SM00839 212 442 2.5E-92 T 31-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 N186_06045 da97cb006c00c33afb8dc482a071d875 444 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 207 442 2.6E-75 T 31-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 N186_06045 da97cb006c00c33afb8dc482a071d875 444 Gene3D G3DSA:3.40.50.720 207 444 1.9E-85 T 31-10-2018 N186_06045 da97cb006c00c33afb8dc482a071d875 444 PIRSF PIRSF000185 28 444 1.8E-166 T 31-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 N186_03790 16fc41b392a029bbec7e4931c6537cf5 402 Pfam PF00753 Metallo-beta-lactamase superfamily 40 172 3.9E-6 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_03790 16fc41b392a029bbec7e4931c6537cf5 402 SMART SM00849 39 230 8.5E-25 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_03790 16fc41b392a029bbec7e4931c6537cf5 402 SUPERFAMILY SSF52218 254 400 3.05E-22 T 31-10-2018 IPR029039 Flavoprotein-like superfamily N186_03790 16fc41b392a029bbec7e4931c6537cf5 402 PIRSF PIRSF005243 7 402 1.5E-97 T 31-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 N186_03790 16fc41b392a029bbec7e4931c6537cf5 402 Gene3D G3DSA:3.60.15.10 1 251 1.3E-83 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_03790 16fc41b392a029bbec7e4931c6537cf5 402 Gene3D G3DSA:3.40.50.360 252 401 1.6E-24 T 31-10-2018 IPR029039 Flavoprotein-like superfamily N186_03790 16fc41b392a029bbec7e4931c6537cf5 402 SUPERFAMILY SSF56281 14 277 1.7E-45 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_05830 92ea5f8e02fc20a47d8e73a723fdf8fc 340 Gene3D G3DSA:3.40.50.11840 23 104 4.6E-70 T 31-10-2018 N186_05830 92ea5f8e02fc20a47d8e73a723fdf8fc 340 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 26 324 1.1E-75 T 31-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 N186_05830 92ea5f8e02fc20a47d8e73a723fdf8fc 340 Pfam PF01866 Putative diphthamide synthesis protein 34 322 2.7E-58 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 N186_05830 92ea5f8e02fc20a47d8e73a723fdf8fc 340 Gene3D G3DSA:3.40.50.11860 216 316 4.6E-70 T 31-10-2018 N186_05830 92ea5f8e02fc20a47d8e73a723fdf8fc 340 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 10 319 4.9E-75 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 N186_05830 92ea5f8e02fc20a47d8e73a723fdf8fc 340 PIRSF PIRSF004967 2 338 6.5E-78 T 31-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 N186_05830 92ea5f8e02fc20a47d8e73a723fdf8fc 340 Gene3D G3DSA:3.40.50.11850 105 215 4.6E-70 T 31-10-2018 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 Pfam PF05191 Adenylate kinase, active site lid 122 157 4.7E-20 T 31-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 PRINTS PR00094 Adenylate kinase signature 4 17 2.0E-31 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 PRINTS PR00094 Adenylate kinase signature 32 46 2.0E-31 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 PRINTS PR00094 Adenylate kinase signature 172 186 2.0E-31 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 PRINTS PR00094 Adenylate kinase signature 155 170 2.0E-31 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 PRINTS PR00094 Adenylate kinase signature 81 97 2.0E-31 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 31-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 TIGRFAM TIGR01351 adk: adenylate kinase 2 205 2.3E-76 T 31-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 Pfam PF00406 Adenylate kinase 6 185 1.4E-47 T 31-10-2018 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 Gene3D G3DSA:3.40.50.300 1 212 2.2E-81 T 31-10-2018 N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 SUPERFAMILY SSF52540 1 210 9.35E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01765 fdfeb248358fbacb8ae80166a2b86cf4 213 Hamap MF_00235 Adenylate kinase [adk]. 1 208 47.042 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_04515 21a21c2485d9b1b338367cfb78eafae4 66 Pfam PF03911 Sec61beta family 24 62 2.8E-13 T 31-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 N186_07005 a94c82e57f8d18a6364828a29172f268 302 PIRSF PIRSF000164 1 302 4.4E-73 T 31-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 N186_07005 a94c82e57f8d18a6364828a29172f268 302 SUPERFAMILY SSF51395 3 301 6.23E-73 T 31-10-2018 N186_07005 a94c82e57f8d18a6364828a29172f268 302 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 7 300 32.577 T 31-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 N186_07005 a94c82e57f8d18a6364828a29172f268 302 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 238 258 - T 31-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 N186_07005 a94c82e57f8d18a6364828a29172f268 302 Gene3D G3DSA:3.20.20.70 1 300 1.2E-83 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_07005 a94c82e57f8d18a6364828a29172f268 302 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 43 62 - T 31-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 N186_07005 a94c82e57f8d18a6364828a29172f268 302 Pfam PF01180 Dihydroorotate dehydrogenase 7 285 3.5E-51 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 N186_07005 a94c82e57f8d18a6364828a29172f268 302 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 7 301 1.6E-90 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 N186_02935 75a2a230d8ddef8170304a7f29dcfe52 329 SUPERFAMILY SSF100950 10 312 1.14E-95 T 31-10-2018 IPR037171 NagB/RpiA transferase-like N186_02935 75a2a230d8ddef8170304a7f29dcfe52 329 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 11 312 2.1E-116 T 31-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 N186_02935 75a2a230d8ddef8170304a7f29dcfe52 329 Gene3D G3DSA:3.40.50.10470 112 300 3.6E-97 T 31-10-2018 N186_02935 75a2a230d8ddef8170304a7f29dcfe52 329 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 12 300 4.0E-88 T 31-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 N186_02935 75a2a230d8ddef8170304a7f29dcfe52 329 Pfam PF01008 Initiation factor 2 subunit family 23 300 3.0E-87 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 N186_02935 75a2a230d8ddef8170304a7f29dcfe52 329 Gene3D G3DSA:1.20.120.420 14 111 3.6E-97 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 N186_01370 509d7cbac0404e00826b65a49e86d4fc 103 Gene3D G3DSA:1.10.10.60 22 59 5.5E-8 T 31-10-2018 N186_01370 509d7cbac0404e00826b65a49e86d4fc 103 SUPERFAMILY SSF47413 24 62 3.56E-6 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 N186_01370 509d7cbac0404e00826b65a49e86d4fc 103 Pfam PF01381 Helix-turn-helix 30 57 4.1E-6 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 N186_08430 dc076c52f91943a38382d9e87d809d0b 208 SUPERFAMILY SSF89155 6 204 5.49E-32 T 31-10-2018 IPR036411 TorD-like superfamily N186_08430 dc076c52f91943a38382d9e87d809d0b 208 Pfam PF02613 Nitrate reductase delta subunit 57 169 1.7E-18 T 31-10-2018 IPR020945 DMSO/Nitrate reductase chaperone N186_08430 dc076c52f91943a38382d9e87d809d0b 208 Gene3D G3DSA:1.10.3480.10 5 205 5.6E-34 T 31-10-2018 N186_06455 edebb093bb04a9d04aa3983929997bb1 315 Gene3D G3DSA:3.40.50.300 74 314 6.6E-64 T 31-10-2018 N186_06455 edebb093bb04a9d04aa3983929997bb1 315 SMART SM00382 102 284 4.6E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_06455 edebb093bb04a9d04aa3983929997bb1 315 SUPERFAMILY SSF52540 83 313 3.25E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06455 edebb093bb04a9d04aa3983929997bb1 315 Gene3D G3DSA:1.10.150.20 12 66 1.7E-13 T 31-10-2018 N186_06455 edebb093bb04a9d04aa3983929997bb1 315 SUPERFAMILY SSF47794 4 63 5.02E-10 T 31-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 N186_06455 edebb093bb04a9d04aa3983929997bb1 315 PIRSF PIRSF005856 3 315 3.7E-91 T 31-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 N186_06455 edebb093bb04a9d04aa3983929997bb1 315 Pfam PF08423 Rad51 84 314 7.2E-66 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 N186_06455 edebb093bb04a9d04aa3983929997bb1 315 Pfam PF14520 Helix-hairpin-helix domain 12 60 2.9E-6 T 31-10-2018 N186_08955 24adfed39971f3fd889609c11d7d25e0 150 Gene3D G3DSA:3.30.460.10 5 102 5.6E-8 T 31-10-2018 N186_08955 24adfed39971f3fd889609c11d7d25e0 150 SUPERFAMILY SSF81301 6 104 5.95E-9 T 31-10-2018 N186_08150 9dc318817306f4563796955714d1adb8 94 Pfam PF14076 Domain of unknown function (DUF4258) 8 72 6.7E-7 T 31-10-2018 IPR025354 Protein of unknown function DUF4258 N186_02640 8955ce07c67b09c1a6bff235a70ffbb1 259 Pfam PF13192 Thioredoxin domain 139 219 1.5E-18 T 31-10-2018 IPR012336 Thioredoxin-like fold N186_02640 8955ce07c67b09c1a6bff235a70ffbb1 259 SUPERFAMILY SSF52833 133 220 9.27E-15 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_02640 8955ce07c67b09c1a6bff235a70ffbb1 259 Gene3D G3DSA:3.40.30.10 3 117 1.5E-28 T 31-10-2018 N186_02640 8955ce07c67b09c1a6bff235a70ffbb1 259 Gene3D G3DSA:3.40.30.10 124 219 8.6E-22 T 31-10-2018 N186_02640 8955ce07c67b09c1a6bff235a70ffbb1 259 SUPERFAMILY SSF52833 10 117 5.9E-15 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_02640 8955ce07c67b09c1a6bff235a70ffbb1 259 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 12 220 5.0E-61 T 31-10-2018 IPR011903 Glutaredoxin-like domain N186_04680 604d8818c4bfa08c9053e635493ba567 322 Gene3D G3DSA:1.10.472.170 22 218 1.7E-56 T 31-10-2018 N186_04680 604d8818c4bfa08c9053e635493ba567 322 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 18 317 39.225 T 31-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea N186_04680 604d8818c4bfa08c9053e635493ba567 322 Pfam PF08271 TFIIB zinc-binding 23 64 3.4E-15 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type N186_04680 604d8818c4bfa08c9053e635493ba567 322 SUPERFAMILY SSF57783 21 67 1.25E-15 T 31-10-2018 N186_04680 604d8818c4bfa08c9053e635493ba567 322 PRINTS PR00685 Transcription initiation factor IIB signature 58 71 2.9E-42 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_04680 604d8818c4bfa08c9053e635493ba567 322 PRINTS PR00685 Transcription initiation factor IIB signature 265 281 2.9E-42 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_04680 604d8818c4bfa08c9053e635493ba567 322 PRINTS PR00685 Transcription initiation factor IIB signature 297 311 2.9E-42 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_04680 604d8818c4bfa08c9053e635493ba567 322 PRINTS PR00685 Transcription initiation factor IIB signature 36 56 2.9E-42 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_04680 604d8818c4bfa08c9053e635493ba567 322 PRINTS PR00685 Transcription initiation factor IIB signature 178 197 2.9E-42 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_04680 604d8818c4bfa08c9053e635493ba567 322 PRINTS PR00685 Transcription initiation factor IIB signature 231 249 2.9E-42 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_04680 604d8818c4bfa08c9053e635493ba567 322 PRINTS PR00685 Transcription initiation factor IIB signature 71 92 2.9E-42 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_04680 604d8818c4bfa08c9053e635493ba567 322 PRINTS PR00685 Transcription initiation factor IIB signature 204 219 2.9E-42 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_04680 604d8818c4bfa08c9053e635493ba567 322 Pfam PF00382 Transcription factor TFIIB repeat 233 302 1.8E-14 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 N186_04680 604d8818c4bfa08c9053e635493ba567 322 Pfam PF00382 Transcription factor TFIIB repeat 139 199 7.4E-17 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 N186_04680 604d8818c4bfa08c9053e635493ba567 322 SUPERFAMILY SSF47954 227 318 1.36E-26 T 31-10-2018 IPR036915 Cyclin-like superfamily N186_04680 604d8818c4bfa08c9053e635493ba567 322 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 264 279 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 N186_04680 604d8818c4bfa08c9053e635493ba567 322 SMART SM00385 136 217 1.6E-9 T 31-10-2018 IPR013763 Cyclin-like N186_04680 604d8818c4bfa08c9053e635493ba567 322 SMART SM00385 230 311 5.6E-8 T 31-10-2018 IPR013763 Cyclin-like N186_04680 604d8818c4bfa08c9053e635493ba567 322 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 170 185 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 N186_04680 604d8818c4bfa08c9053e635493ba567 322 SUPERFAMILY SSF47954 134 224 1.63E-23 T 31-10-2018 IPR036915 Cyclin-like superfamily N186_04680 604d8818c4bfa08c9053e635493ba567 322 Gene3D G3DSA:1.10.472.10 227 320 9.8E-25 T 31-10-2018 N186_05410 d373d44116f46ca9203f557afc615d56 492 Pfam PF07969 Amidohydrolase family 43 448 2.9E-74 T 31-10-2018 IPR013108 Amidohydrolase 3 N186_05410 d373d44116f46ca9203f557afc615d56 492 Gene3D G3DSA:3.10.310.70 73 188 5.6E-29 T 31-10-2018 N186_05410 d373d44116f46ca9203f557afc615d56 492 SUPERFAMILY SSF51338 25 67 1.99E-6 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 N186_05410 d373d44116f46ca9203f557afc615d56 492 Gene3D G3DSA:3.20.20.140 189 454 1.6E-68 T 31-10-2018 N186_05410 d373d44116f46ca9203f557afc615d56 492 Gene3D G3DSA:2.30.40.10 3 69 1.8E-7 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 N186_05410 d373d44116f46ca9203f557afc615d56 492 SUPERFAMILY SSF51556 54 447 1.57E-27 T 31-10-2018 IPR032466 Metal-dependent hydrolase N186_01700 55b64baedd469e468154189460c44bd2 103 SUPERFAMILY SSF51230 28 102 1.22E-20 T 31-10-2018 IPR011053 Single hybrid motif N186_01700 55b64baedd469e468154189460c44bd2 103 Gene3D G3DSA:2.40.50.100 31 102 6.5E-22 T 31-10-2018 N186_01700 55b64baedd469e468154189460c44bd2 103 Pfam PF00364 Biotin-requiring enzyme 39 102 1.7E-16 T 31-10-2018 IPR000089 Biotin/lipoyl attachment N186_01700 55b64baedd469e468154189460c44bd2 103 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 59 76 - T 31-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 N186_00425 c0d154bbf19ee3fa34528a7c3da1c5c7 119 Pfam PF13650 Aspartyl protease 22 86 6.9E-6 T 31-10-2018 N186_00425 c0d154bbf19ee3fa34528a7c3da1c5c7 119 Gene3D G3DSA:2.40.70.10 2 112 1.5E-6 T 31-10-2018 IPR021109 Aspartic peptidase domain superfamily N186_00425 c0d154bbf19ee3fa34528a7c3da1c5c7 119 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 24 35 - T 31-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 N186_00425 c0d154bbf19ee3fa34528a7c3da1c5c7 119 SUPERFAMILY SSF50630 21 102 1.41E-8 T 31-10-2018 IPR021109 Aspartic peptidase domain superfamily N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 Gene3D G3DSA:1.10.8.660 372 422 2.4E-15 T 31-10-2018 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 SUPERFAMILY SSF55035 113 220 3.14E-33 T 31-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 Gene3D G3DSA:3.30.70.420 112 221 3.6E-136 T 31-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 Gene3D G3DSA:3.90.770.10 15 368 3.6E-136 T 31-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 17 382 1.8E-113 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 3 382 8.0E-151 T 31-10-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 367 380 - T 31-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 177 191 - T 31-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 SUPERFAMILY SSF56542 8 423 3.14E-104 T 31-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 175 193 2.5E-6 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 52 73 2.5E-6 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 309 330 2.5E-6 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 79 99 2.5E-6 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06200 74fa62d0193bd8de116e3c07c247d5d2 427 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 321 328 - T 31-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 N186_06470 1375c85bc996ede6ffe7835b3545959f 259 SUPERFAMILY SSF52540 62 257 5.26E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06470 1375c85bc996ede6ffe7835b3545959f 259 Pfam PF02223 Thymidylate kinase 67 241 4.7E-47 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 N186_06470 1375c85bc996ede6ffe7835b3545959f 259 Hamap MF_00165 Thymidylate kinase [tmk]. 63 251 25.407 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 N186_06470 1375c85bc996ede6ffe7835b3545959f 259 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 62 240 5.5E-50 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 N186_06470 1375c85bc996ede6ffe7835b3545959f 259 Gene3D G3DSA:3.40.50.300 61 256 1.6E-58 T 31-10-2018 N186_04275 0d5938cc3d5e60ed8fa72dabc4f8c856 352 SMART SM01194 1 129 5.6E-33 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like N186_04275 0d5938cc3d5e60ed8fa72dabc4f8c856 352 Pfam PF03463 eRF1 domain 1 8 127 6.5E-21 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like N186_04275 0d5938cc3d5e60ed8fa72dabc4f8c856 352 Gene3D G3DSA:3.30.1330.30 254 352 1.1E-19 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like N186_04275 0d5938cc3d5e60ed8fa72dabc4f8c856 352 Gene3D G3DSA:2.30.30.870 1 130 1.5E-35 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain N186_04275 0d5938cc3d5e60ed8fa72dabc4f8c856 352 Gene3D G3DSA:3.30.420.60 132 250 4.2E-12 T 31-10-2018 N186_04275 0d5938cc3d5e60ed8fa72dabc4f8c856 352 SUPERFAMILY SSF55315 247 349 8.83E-18 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like N186_04275 0d5938cc3d5e60ed8fa72dabc4f8c856 352 SUPERFAMILY SSF159065 2 127 3.14E-29 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain N186_04275 0d5938cc3d5e60ed8fa72dabc4f8c856 352 Hamap MF_01853 Protein pelota homolog [pelA]. 2 350 27.62 T 31-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 N186_04275 0d5938cc3d5e60ed8fa72dabc4f8c856 352 Pfam PF03465 eRF1 domain 3 256 348 1.3E-11 T 31-10-2018 IPR005142 eRF1 domain 3 N186_03365 e38342ca0bab2307352201890c697830 596 Pfam PF06733 DEAD_2 73 236 6.0E-20 T 31-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 N186_03365 e38342ca0bab2307352201890c697830 596 Pfam PF13307 Helicase C-terminal domain 433 577 2.2E-21 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 N186_03365 e38342ca0bab2307352201890c697830 596 Gene3D G3DSA:1.10.275.30 228 341 1.7E-61 T 31-10-2018 N186_03365 e38342ca0bab2307352201890c697830 596 Gene3D G3DSA:3.40.50.300 394 587 4.9E-41 T 31-10-2018 N186_03365 e38342ca0bab2307352201890c697830 596 SUPERFAMILY SSF52540 12 248 5.96E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03365 e38342ca0bab2307352201890c697830 596 Gene3D G3DSA:3.40.50.300 25 378 1.7E-61 T 31-10-2018 N186_03365 e38342ca0bab2307352201890c697830 596 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 209 218 - T 31-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site N186_03365 e38342ca0bab2307352201890c697830 596 SMART SM00491 442 576 2.5E-14 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 N186_03365 e38342ca0bab2307352201890c697830 596 SMART SM00488 15 270 1.4E-8 T 31-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 N186_02555 8b0a91e42d6b8c28d1748e3f1be609bd 177 PIRSF PIRSF005067 1 177 5.3E-41 T 31-10-2018 IPR016437 MCT-1/Tma20 N186_02555 8b0a91e42d6b8c28d1748e3f1be609bd 177 Pfam PF09183 Domain of unknown function (DUF1947) 12 85 7.8E-7 T 31-10-2018 IPR015266 Domain of unknown function DUF1947 N186_02555 8b0a91e42d6b8c28d1748e3f1be609bd 177 Gene3D G3DSA:3.10.450.120 16 175 1.1E-27 T 31-10-2018 N186_02555 8b0a91e42d6b8c28d1748e3f1be609bd 177 Pfam PF01472 PUA domain 94 167 1.1E-19 T 31-10-2018 IPR002478 PUA domain GO:0003723 N186_02555 8b0a91e42d6b8c28d1748e3f1be609bd 177 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 13 174 1.3E-39 T 31-10-2018 IPR022430 Conserved hypothetical protein CHP03684 N186_02555 8b0a91e42d6b8c28d1748e3f1be609bd 177 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 73 169 7.4E-23 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 N186_02555 8b0a91e42d6b8c28d1748e3f1be609bd 177 Gene3D G3DSA:2.30.130.10 89 168 1.1E-27 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 N186_02555 8b0a91e42d6b8c28d1748e3f1be609bd 177 SUPERFAMILY SSF88697 92 174 5.52E-22 T 31-10-2018 IPR015947 PUA-like superfamily N186_02555 8b0a91e42d6b8c28d1748e3f1be609bd 177 SMART SM00359 93 168 4.6E-17 T 31-10-2018 IPR002478 PUA domain GO:0003723 N186_07170 a1c78016b98aa3dd8e38df4fe89e9445 240 Gene3D G3DSA:3.40.50.300 4 235 1.1E-53 T 31-10-2018 N186_07170 a1c78016b98aa3dd8e38df4fe89e9445 240 SUPERFAMILY SSF52540 4 225 3.13E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07170 a1c78016b98aa3dd8e38df4fe89e9445 240 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 237 1.1E-66 T 31-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 N186_07170 a1c78016b98aa3dd8e38df4fe89e9445 240 SMART SM00382 30 218 1.1E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_07170 a1c78016b98aa3dd8e38df4fe89e9445 240 Pfam PF00005 ABC transporter 21 166 1.2E-23 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_07170 a1c78016b98aa3dd8e38df4fe89e9445 240 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_07150 6cb721b5822836b8ae5d97319b2e655f 241 Gene3D G3DSA:3.40.50.300 4 160 1.5E-12 T 31-10-2018 N186_07150 6cb721b5822836b8ae5d97319b2e655f 241 Pfam PF05331 Protein of unknown function (DUF742) 174 239 6.5E-5 T 31-10-2018 IPR007995 Protein of unknown function DUF742 N186_07150 6cb721b5822836b8ae5d97319b2e655f 241 SUPERFAMILY SSF52540 6 149 4.73E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07150 6cb721b5822836b8ae5d97319b2e655f 241 SUPERFAMILY SSF46894 175 230 1.22E-5 T 31-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 N186_00595 845c51329f650f3ab58e41d2eabb765d 135 Gene3D G3DSA:3.40.1260.10 1 135 9.1E-31 T 31-10-2018 IPR027396 DsrEFH-like N186_00595 845c51329f650f3ab58e41d2eabb765d 135 Pfam PF13686 DsrE/DsrF/DrsH-like family 61 131 5.8E-7 T 31-10-2018 IPR032836 DsrE2-like family N186_00595 845c51329f650f3ab58e41d2eabb765d 135 SUPERFAMILY SSF75169 3 122 2.16E-13 T 31-10-2018 IPR027396 DsrEFH-like N186_05965 1501295c5e3f29c62991f537da323060 79 Gene3D G3DSA:2.30.30.90 13 74 1.8E-16 T 31-10-2018 IPR038157 Ferrous iron transporter, core domain N186_05965 1501295c5e3f29c62991f537da323060 79 Pfam PF04023 FeoA domain 7 74 3.3E-15 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 N186_05965 1501295c5e3f29c62991f537da323060 79 SMART SM00899 5 75 3.5E-13 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 N186_05965 1501295c5e3f29c62991f537da323060 79 SUPERFAMILY SSF50037 7 75 7.14E-15 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal N186_06130 e990f866a33b28fa5a19b412ecab12d5 362 Pfam PF00005 ABC transporter 25 169 1.4E-37 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_06130 e990f866a33b28fa5a19b412ecab12d5 362 Gene3D G3DSA:2.40.50.940 230 359 1.7E-8 T 31-10-2018 N186_06130 e990f866a33b28fa5a19b412ecab12d5 362 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_06130 e990f866a33b28fa5a19b412ecab12d5 362 Gene3D G3DSA:3.40.50.300 6 229 3.1E-72 T 31-10-2018 N186_06130 e990f866a33b28fa5a19b412ecab12d5 362 SUPERFAMILY SSF50331 245 359 5.67E-11 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal N186_06130 e990f866a33b28fa5a19b412ecab12d5 362 Gene3D G3DSA:2.40.50.140 289 350 1.7E-8 T 31-10-2018 N186_06130 e990f866a33b28fa5a19b412ecab12d5 362 SUPERFAMILY SSF52540 7 250 3.96E-85 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06130 e990f866a33b28fa5a19b412ecab12d5 362 SMART SM00382 34 227 2.5E-20 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00530 6416c8bbcefc524d506c78249e0540c2 234 Gene3D G3DSA:3.40.50.300 3 231 3.9E-61 T 31-10-2018 N186_00530 6416c8bbcefc524d506c78249e0540c2 234 SMART SM00382 29 231 4.4E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00530 6416c8bbcefc524d506c78249e0540c2 234 SUPERFAMILY SSF52540 4 220 1.16E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00530 6416c8bbcefc524d506c78249e0540c2 234 Pfam PF00005 ABC transporter 20 167 7.2E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00530 6416c8bbcefc524d506c78249e0540c2 234 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_03835 12cdcd0f5be5442e0af077b5971693b3 79 ProSitePatterns PS00961 Ribosomal protein S28e signature. 68 76 - T 31-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03835 12cdcd0f5be5442e0af077b5971693b3 79 SUPERFAMILY SSF50249 13 78 1.46E-25 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_03835 12cdcd0f5be5442e0af077b5971693b3 79 Gene3D G3DSA:2.40.50.140 12 79 1.8E-31 T 31-10-2018 N186_03835 12cdcd0f5be5442e0af077b5971693b3 79 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 77 26.092 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03835 12cdcd0f5be5442e0af077b5971693b3 79 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 18 58 1.0E-13 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03835 12cdcd0f5be5442e0af077b5971693b3 79 Pfam PF01200 Ribosomal protein S28e 14 76 8.1E-30 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_06395 d75df547289623e6b80347d3ebc6727b 224 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 5 219 6.7E-70 T 31-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding N186_06395 d75df547289623e6b80347d3ebc6727b 224 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 2 221 1.0E-60 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 N186_06395 d75df547289623e6b80347d3ebc6727b 224 Gene3D G3DSA:3.40.50.620 1 125 2.4E-34 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_06395 d75df547289623e6b80347d3ebc6727b 224 Pfam PF01902 Diphthamide synthase 2 219 1.4E-59 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 N186_06395 d75df547289623e6b80347d3ebc6727b 224 Gene3D G3DSA:3.90.1490.10 126 224 1.3E-24 T 31-10-2018 N186_06395 d75df547289623e6b80347d3ebc6727b 224 SUPERFAMILY SSF52402 2 223 2.07E-59 T 31-10-2018 N186_06395 d75df547289623e6b80347d3ebc6727b 224 PIRSF PIRSF039123 1 224 2.9E-71 T 31-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 N186_03980 7c2994af209843008074f96dfa2c4b3e 252 Gene3D G3DSA:3.40.50.300 1 240 1.1E-65 T 31-10-2018 N186_03980 7c2994af209843008074f96dfa2c4b3e 252 SMART SM00382 26 209 1.0E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_03980 7c2994af209843008074f96dfa2c4b3e 252 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_03980 7c2994af209843008074f96dfa2c4b3e 252 SUPERFAMILY SSF52540 2 222 1.31E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03980 7c2994af209843008074f96dfa2c4b3e 252 Pfam PF00005 ABC transporter 17 161 9.6E-24 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_03025 4afffaaade435135ae95e347217055ae 299 SUPERFAMILY SSF54631 6 66 5.23E-10 T 31-10-2018 N186_03025 4afffaaade435135ae95e347217055ae 299 SUPERFAMILY SSF54631 221 274 4.22E-11 T 31-10-2018 N186_03025 4afffaaade435135ae95e347217055ae 299 Pfam PF00571 CBS domain 13 60 9.0E-7 T 31-10-2018 IPR000644 CBS domain N186_03025 4afffaaade435135ae95e347217055ae 299 Pfam PF00571 CBS domain 148 202 1.4E-12 T 31-10-2018 IPR000644 CBS domain N186_03025 4afffaaade435135ae95e347217055ae 299 Pfam PF00571 CBS domain 87 140 4.8E-11 T 31-10-2018 IPR000644 CBS domain N186_03025 4afffaaade435135ae95e347217055ae 299 Pfam PF00571 CBS domain 226 275 1.4E-10 T 31-10-2018 IPR000644 CBS domain N186_03025 4afffaaade435135ae95e347217055ae 299 Gene3D G3DSA:3.10.580.10 12 144 2.8E-22 T 31-10-2018 N186_03025 4afffaaade435135ae95e347217055ae 299 Gene3D G3DSA:3.10.580.10 145 292 1.6E-32 T 31-10-2018 N186_03025 4afffaaade435135ae95e347217055ae 299 SUPERFAMILY SSF54631 87 204 1.12E-27 T 31-10-2018 N186_03025 4afffaaade435135ae95e347217055ae 299 SMART SM00116 155 202 4.2E-11 T 31-10-2018 IPR000644 CBS domain N186_03025 4afffaaade435135ae95e347217055ae 299 SMART SM00116 92 140 4.8E-10 T 31-10-2018 IPR000644 CBS domain N186_03025 4afffaaade435135ae95e347217055ae 299 SMART SM00116 229 276 1.0E-9 T 31-10-2018 IPR000644 CBS domain N186_03025 4afffaaade435135ae95e347217055ae 299 SMART SM00116 13 61 1.3E-5 T 31-10-2018 IPR000644 CBS domain N186_04510 f5e7bce85ceb35ad2d4e3d26b9711226 248 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 10 233 5.3E-75 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 N186_04510 f5e7bce85ceb35ad2d4e3d26b9711226 248 Gene3D G3DSA:3.20.20.390 1 240 7.2E-91 T 31-10-2018 IPR038597 GGGP/HepGP synthase superfamily N186_04510 f5e7bce85ceb35ad2d4e3d26b9711226 248 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 5 235 34.994 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 N186_04510 f5e7bce85ceb35ad2d4e3d26b9711226 248 SUPERFAMILY SSF51395 6 226 4.03E-43 T 31-10-2018 N186_04510 f5e7bce85ceb35ad2d4e3d26b9711226 248 Pfam PF01884 PcrB family 4 234 1.2E-57 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 N186_04510 f5e7bce85ceb35ad2d4e3d26b9711226 248 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 11 216 1.2E-78 T 31-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 N186_03105 61899f17806f6c32aec6902e903942ba 319 SUPERFAMILY SSF53335 5 316 1.55E-83 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_03105 61899f17806f6c32aec6902e903942ba 319 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 7 174 4.7E-33 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03105 61899f17806f6c32aec6902e903942ba 319 Pfam PF00145 C-5 cytosine-specific DNA methylase 255 316 3.4E-14 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03105 61899f17806f6c32aec6902e903942ba 319 Pfam PF00145 C-5 cytosine-specific DNA methylase 5 174 1.4E-36 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03105 61899f17806f6c32aec6902e903942ba 319 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 119 133 1.3E-13 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03105 61899f17806f6c32aec6902e903942ba 319 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 163 176 1.3E-13 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03105 61899f17806f6c32aec6902e903942ba 319 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 6 22 1.3E-13 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03105 61899f17806f6c32aec6902e903942ba 319 Gene3D G3DSA:3.90.120.10 242 304 4.1E-19 T 31-10-2018 N186_03105 61899f17806f6c32aec6902e903942ba 319 Gene3D G3DSA:3.40.50.150 2 196 3.7E-50 T 31-10-2018 N186_05285 e6e12ba29a8ec361ce084b43543ce8e0 290 Pfam PF01040 UbiA prenyltransferase family 40 279 1.9E-48 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 N186_05285 e6e12ba29a8ec361ce084b43543ce8e0 290 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 66 88 - T 31-10-2018 IPR030470 UbiA prenyltransferase conserved site N186_05285 e6e12ba29a8ec361ce084b43543ce8e0 290 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 8 289 14.75 T 31-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 N186_05285 e6e12ba29a8ec361ce084b43543ce8e0 290 Gene3D G3DSA:1.10.357.140 15 172 3.5E-16 T 31-10-2018 N186_05285 e6e12ba29a8ec361ce084b43543ce8e0 290 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 10 289 3.3E-67 T 31-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 N186_02645 d2936928042a8395c469ed5a37c44882 236 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 59 228 2.5E-45 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 N186_02645 d2936928042a8395c469ed5a37c44882 236 Gene3D G3DSA:3.40.50.1360 19 225 2.4E-61 T 31-10-2018 N186_02645 d2936928042a8395c469ed5a37c44882 236 SUPERFAMILY SSF75445 139 216 5.89E-15 T 31-10-2018 N186_02645 d2936928042a8395c469ed5a37c44882 236 Gene3D G3DSA:3.30.70.260 134 214 2.4E-61 T 31-10-2018 N186_02645 d2936928042a8395c469ed5a37c44882 236 SMART SM01134 8 147 0.0071 T 31-10-2018 N186_02645 d2936928042a8395c469ed5a37c44882 236 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 14 230 1.3E-57 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 N186_02645 d2936928042a8395c469ed5a37c44882 236 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 10 235 27.753 T 31-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 N186_02645 d2936928042a8395c469ed5a37c44882 236 SUPERFAMILY SSF100950 10 188 7.26E-36 T 31-10-2018 IPR037171 NagB/RpiA transferase-like N186_09430 f4ef80f21b5d1f5508740dc94b6f7278 283 SUPERFAMILY SSF46785 224 274 1.15E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_09430 f4ef80f21b5d1f5508740dc94b6f7278 283 Pfam PF13412 Winged helix-turn-helix DNA-binding 240 268 7.4E-6 T 31-10-2018 N186_09430 f4ef80f21b5d1f5508740dc94b6f7278 283 Gene3D G3DSA:1.10.10.10 219 281 4.9E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_06770 4853d4a735e589761db633e2d0481b67 335 PIRSF PIRSF000808 1 318 1.1E-95 T 31-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 N186_06770 4853d4a735e589761db633e2d0481b67 335 Gene3D G3DSA:3.30.428.10 7 313 8.7E-84 T 31-10-2018 IPR036265 HIT-like superfamily N186_06770 4853d4a735e589761db633e2d0481b67 335 SUPERFAMILY SSF54197 158 317 2.67E-39 T 31-10-2018 IPR036265 HIT-like superfamily N186_06770 4853d4a735e589761db633e2d0481b67 335 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 162 280 1.1E-18 T 31-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 N186_06770 4853d4a735e589761db633e2d0481b67 335 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 6 293 7.7E-48 T 31-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 N186_06770 4853d4a735e589761db633e2d0481b67 335 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 6 155 5.1E-19 T 31-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 N186_06770 4853d4a735e589761db633e2d0481b67 335 SUPERFAMILY SSF54197 4 156 8.0E-40 T 31-10-2018 IPR036265 HIT-like superfamily N186_06770 4853d4a735e589761db633e2d0481b67 335 Gene3D G3DSA:3.30.428.10 35 154 8.7E-84 T 31-10-2018 IPR036265 HIT-like superfamily N186_00840 fdd85de1560b7b129258c3058a5ab15e 183 Gene3D G3DSA:2.20.28.10 146 183 5.3E-15 T 31-10-2018 N186_00840 fdd85de1560b7b129258c3058a5ab15e 183 SUPERFAMILY SSF57802 150 181 4.35E-10 T 31-10-2018 N186_00840 fdd85de1560b7b129258c3058a5ab15e 183 SUPERFAMILY SSF47240 1 144 3.94E-39 T 31-10-2018 IPR009078 Ferritin-like superfamily N186_00840 fdd85de1560b7b129258c3058a5ab15e 183 Gene3D G3DSA:1.20.1260.10 1 143 6.4E-46 T 31-10-2018 IPR012347 Ferritin-like N186_00840 fdd85de1560b7b129258c3058a5ab15e 183 Pfam PF02915 Rubrerythrin 7 135 1.0E-30 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 N186_03380 154abb6265f16d202469e7967ecc8ea9 156 ProSitePatterns PS00519 AsnC-type HTH domain signature. 28 54 - T 31-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site N186_03380 154abb6265f16d202469e7967ecc8ea9 156 SUPERFAMILY SSF46785 9 69 8.71E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_03380 154abb6265f16d202469e7967ecc8ea9 156 SUPERFAMILY SSF54909 72 153 3.49E-19 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel N186_03380 154abb6265f16d202469e7967ecc8ea9 156 Pfam PF01037 Lrp/AsnC ligand binding domain 79 145 9.8E-18 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain N186_03380 154abb6265f16d202469e7967ecc8ea9 156 Gene3D G3DSA:3.30.70.920 63 156 2.7E-26 T 31-10-2018 N186_03380 154abb6265f16d202469e7967ecc8ea9 156 Gene3D G3DSA:1.10.10.10 1 62 3.5E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_03380 154abb6265f16d202469e7967ecc8ea9 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 1.3E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_03380 154abb6265f16d202469e7967ecc8ea9 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 1.3E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_03380 154abb6265f16d202469e7967ecc8ea9 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 1.3E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_03380 154abb6265f16d202469e7967ecc8ea9 156 SMART SM00344 10 116 3.8E-47 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 N186_03380 154abb6265f16d202469e7967ecc8ea9 156 Pfam PF13404 AsnC-type helix-turn-helix domain 10 50 4.5E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 484 37.126 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 SUPERFAMILY SSF55681 12 280 4.02E-75 T 31-10-2018 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 Gene3D G3DSA:3.40.50.800 288 407 5.9E-36 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 SUPERFAMILY SSF52954 281 408 3.02E-32 T 31-10-2018 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 PRINTS PR01046 Prolyl-tRNA synthetase signature 66 84 9.2E-7 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 PRINTS PR01046 Prolyl-tRNA synthetase signature 139 147 9.2E-7 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 PRINTS PR01046 Prolyl-tRNA synthetase signature 148 159 9.2E-7 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 Gene3D G3DSA:3.30.110.30 410 483 4.6E-22 T 31-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 104 275 1.6E-30 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 SMART SM00946 416 484 4.5E-22 T 31-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 Pfam PF03129 Anticodon binding domain 293 388 9.1E-19 T 31-10-2018 IPR004154 Anticodon-binding N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 418 484 7.1E-14 T 31-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 8 484 1.8E-159 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 Gene3D G3DSA:3.30.930.10 1 286 2.6E-91 T 31-10-2018 N186_05615 46c373179bac38f1213236f4fb8a5ffe 484 SUPERFAMILY SSF64586 411 484 3.53E-13 T 31-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 PIRSF PIRSF002144 4 122 2.3E-35 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 Gene3D G3DSA:3.30.860.20 1 122 9.2E-44 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 SUPERFAMILY SSF54570 31 106 2.62E-27 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 Pfam PF00203 Ribosomal protein S19 24 105 2.0E-31 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 PRINTS PR00975 Ribosomal protein S19 family signature 87 102 1.3E-16 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 PRINTS PR00975 Ribosomal protein S19 family signature 75 87 1.3E-16 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 PRINTS PR00975 Ribosomal protein S19 family signature 55 74 1.3E-16 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 1 122 3.1E-50 T 31-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 14 111 22.792 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01970 56bee533fd39461266f8f590bea2ec7d 122 ProSitePatterns PS00323 Ribosomal protein S19 signature. 75 99 - T 31-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03785 27ea24484e3a9f01f25d44770ffaf3bb 152 SUPERFAMILY SSF49764 25 151 5.08E-25 T 31-10-2018 IPR008978 HSP20-like chaperone N186_03785 27ea24484e3a9f01f25d44770ffaf3bb 152 Gene3D G3DSA:2.60.40.790 13 151 9.2E-27 T 31-10-2018 IPR008978 HSP20-like chaperone N186_03785 27ea24484e3a9f01f25d44770ffaf3bb 152 Pfam PF00011 Hsp20/alpha crystallin family 51 147 3.8E-16 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain N186_08060 f6a2f631f478722871b58a59ce88f3ad 122 Pfam PF13975 gag-polyprotein putative aspartyl protease 23 100 3.8E-7 T 31-10-2018 N186_08060 f6a2f631f478722871b58a59ce88f3ad 122 SUPERFAMILY SSF50630 22 106 1.73E-8 T 31-10-2018 IPR021109 Aspartic peptidase domain superfamily N186_08060 f6a2f631f478722871b58a59ce88f3ad 122 Gene3D G3DSA:2.40.70.10 3 119 6.3E-11 T 31-10-2018 IPR021109 Aspartic peptidase domain superfamily N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 288 1.1E-119 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 290 41.049 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 SMART SM00881 4 101 4.7E-36 T 31-10-2018 IPR003781 CoA-binding GO:0048037 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 Gene3D G3DSA:3.40.50.720 1 124 6.7E-51 T 31-10-2018 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 PRINTS PR01798 Succinyl-CoA synthase signature 209 222 1.5E-30 T 31-10-2018 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 PRINTS PR01798 Succinyl-CoA synthase signature 83 100 1.5E-30 T 31-10-2018 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 PRINTS PR01798 Succinyl-CoA synthase signature 178 196 1.5E-30 T 31-10-2018 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 PRINTS PR01798 Succinyl-CoA synthase signature 242 259 1.5E-30 T 31-10-2018 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 Gene3D G3DSA:3.40.50.261 125 292 5.4E-61 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 SUPERFAMILY SSF51735 1 123 1.08E-39 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 Pfam PF02629 CoA binding domain 6 100 3.8E-33 T 31-10-2018 IPR003781 CoA-binding GO:0048037 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 286 1.0E-13 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 SUPERFAMILY SSF52210 124 290 2.88E-44 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 PIRSF PIRSF001553 1 293 7.1E-125 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 N186_03545 cc49528097e7c8d28ddbc9b0daac15ff 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 153 182 - T 31-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site N186_06335 58a5741418bb06c7f1c7dafc3c56a282 415 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 10 412 8.5E-158 T 31-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 N186_06335 58a5741418bb06c7f1c7dafc3c56a282 415 Gene3D G3DSA:3.40.640.10 38 302 1.1E-157 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 N186_06335 58a5741418bb06c7f1c7dafc3c56a282 415 Pfam PF00266 Aminotransferase class-V 27 402 1.2E-133 T 31-10-2018 IPR000192 Aminotransferase class V domain N186_06335 58a5741418bb06c7f1c7dafc3c56a282 415 SUPERFAMILY SSF53383 6 410 9.49E-123 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase N186_06335 58a5741418bb06c7f1c7dafc3c56a282 415 Gene3D G3DSA:3.90.1150.10 10 405 1.1E-157 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 N186_06335 58a5741418bb06c7f1c7dafc3c56a282 415 PIRSF PIRSF005572 24 415 1.8E-51 T 31-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 N186_01650 c434584c670fc5cd4753e482f8f2006a 330 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_01650 c434584c670fc5cd4753e482f8f2006a 330 Gene3D G3DSA:3.40.50.300 5 330 1.1E-87 T 31-10-2018 N186_01650 c434584c670fc5cd4753e482f8f2006a 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 304 3.9E-21 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_01650 c434584c670fc5cd4753e482f8f2006a 330 Pfam PF00005 ABC transporter 33 186 3.8E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_01650 c434584c670fc5cd4753e482f8f2006a 330 SMART SM00382 42 251 1.0E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01650 c434584c670fc5cd4753e482f8f2006a 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 324 4.0E-27 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_01650 c434584c670fc5cd4753e482f8f2006a 330 SUPERFAMILY SSF52540 7 258 1.33E-62 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 573 8.5E-144 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 SUPERFAMILY SSF52374 4 583 8.08E-133 T 31-10-2018 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 789 2.3E-262 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 Gene3D G3DSA:1.10.730.10 6 743 1.5E-240 T 31-10-2018 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 Pfam PF08264 Anticodon-binding domain of tRNA 613 755 1.3E-34 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 SUPERFAMILY SSF47323 586 794 6.17E-44 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 SUPERFAMILY SSF50677 195 342 9.81E-50 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 Gene3D G3DSA:3.90.740.10 177 344 1.5E-240 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 Gene3D G3DSA:3.40.50.620 26 534 1.5E-240 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 PRINTS PR00986 Valyl-tRNA synthetase signature 232 249 8.8E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 PRINTS PR00986 Valyl-tRNA synthetase signature 456 477 8.8E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 PRINTS PR00986 Valyl-tRNA synthetase signature 347 360 8.8E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 PRINTS PR00986 Valyl-tRNA synthetase signature 485 503 8.8E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 PRINTS PR00986 Valyl-tRNA synthetase signature 41 52 8.8E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 N186_02635 b88a423cf058d3662cc6f5b9ba8db78c 808 Hamap MF_02005 Valine--tRNA ligase [valS]. 6 786 27.038 T 31-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 Gene3D G3DSA:2.40.30.20 2 75 3.6E-26 T 31-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 Gene3D G3DSA:1.10.1140.10 440 591 2.8E-39 T 31-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 430 439 - T 31-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 216 439 1.8E-85 T 31-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 10 72 3.0E-10 T 31-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 SUPERFAMILY SSF47917 452 546 1.73E-14 T 31-10-2018 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 Gene3D G3DSA:3.40.50.300 78 439 6.0E-172 T 31-10-2018 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 5 589 49.458 T 31-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 SUPERFAMILY SSF50615 5 75 3.14E-11 T 31-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 SUPERFAMILY SSF52540 151 444 6.64E-76 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 88 207 3.9E-48 T 31-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_02720 1ffe8d346ff604d814c40a8bde0dc45c 602 Gene3D G3DSA:2.40.50.100 119 189 6.0E-172 T 31-10-2018 N186_01015 646136aafc7365534bce1f259f4052eb 158 Pfam PF02915 Rubrerythrin 23 127 1.4E-6 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 N186_01015 646136aafc7365534bce1f259f4052eb 158 SUPERFAMILY SSF47240 5 133 2.14E-12 T 31-10-2018 IPR009078 Ferritin-like superfamily N186_01015 646136aafc7365534bce1f259f4052eb 158 Gene3D G3DSA:1.20.1260.10 2 133 2.1E-8 T 31-10-2018 IPR012347 Ferritin-like N186_05340 12f94a099f03559005aef3008180a912 346 Gene3D G3DSA:3.40.47.10 5 340 2.3E-68 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_05340 12f94a099f03559005aef3008180a912 346 SUPERFAMILY SSF53901 5 165 7.93E-30 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_05340 12f94a099f03559005aef3008180a912 346 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 5 342 5.3E-147 T 31-10-2018 IPR004656 Putative condensing enzyme FabH-related N186_05340 12f94a099f03559005aef3008180a912 346 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 301 1.2E-13 T 31-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 N186_05340 12f94a099f03559005aef3008180a912 346 SUPERFAMILY SSF53901 171 344 1.05E-42 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_01505 54633c8da6fd5df8649d775902dc6d8e 292 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 80 94 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site N186_01505 54633c8da6fd5df8649d775902dc6d8e 292 Gene3D G3DSA:1.10.600.10 3 288 4.2E-54 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily N186_01505 54633c8da6fd5df8649d775902dc6d8e 292 SUPERFAMILY SSF48576 17 220 4.73E-43 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily N186_01505 54633c8da6fd5df8649d775902dc6d8e 292 Pfam PF00348 Polyprenyl synthetase 32 216 5.4E-38 T 31-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 N186_01505 54633c8da6fd5df8649d775902dc6d8e 292 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 199 211 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site N186_02585 80d47e0d40a1972ccaf46e53e449dc7e 401 SUPERFAMILY SSF53187 4 400 4.19E-53 T 31-10-2018 N186_02585 80d47e0d40a1972ccaf46e53e449dc7e 401 Gene3D G3DSA:3.30.70.360 187 319 5.7E-66 T 31-10-2018 N186_02585 80d47e0d40a1972ccaf46e53e449dc7e 401 Pfam PF07687 Peptidase dimerisation domain 184 297 6.9E-17 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain N186_02585 80d47e0d40a1972ccaf46e53e449dc7e 401 Gene3D G3DSA:3.40.630.10 11 389 5.7E-66 T 31-10-2018 N186_02585 80d47e0d40a1972ccaf46e53e449dc7e 401 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 76 85 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 N186_02585 80d47e0d40a1972ccaf46e53e449dc7e 401 SUPERFAMILY SSF55031 187 311 7.18E-17 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain N186_02585 80d47e0d40a1972ccaf46e53e449dc7e 401 Pfam PF01546 Peptidase family M20/M25/M40 78 400 3.4E-29 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 N186_06920 66737ca3bfbea730bf82174490f275f1 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 190 5.7E-7 T 31-10-2018 N186_06920 66737ca3bfbea730bf82174490f275f1 213 SUPERFAMILY SSF56784 4 200 4.64E-23 T 31-10-2018 IPR036412 HAD-like superfamily N186_06920 66737ca3bfbea730bf82174490f275f1 213 Gene3D G3DSA:3.40.50.1000 5 198 5.3E-17 T 31-10-2018 IPR023214 HAD superfamily N186_06920 66737ca3bfbea730bf82174490f275f1 213 Gene3D G3DSA:1.10.150.520 18 90 5.3E-17 T 31-10-2018 N186_06920 66737ca3bfbea730bf82174490f275f1 213 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 31-10-2018 N186_06545 3a57389e21062c0a95e951af55722d24 335 SMART SM00966 12 58 1.7E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_06545 3a57389e21062c0a95e951af55722d24 335 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 13 52 5.5E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_06545 3a57389e21062c0a95e951af55722d24 335 Gene3D G3DSA:1.20.58.220 242 335 6.3E-6 T 31-10-2018 IPR038078 PhoU-like domain superfamily N186_06545 3a57389e21062c0a95e951af55722d24 335 Pfam PF01895 PhoU domain 144 233 1.4E-12 T 31-10-2018 IPR026022 PhoU domain N186_06545 3a57389e21062c0a95e951af55722d24 335 SUPERFAMILY SSF109755 133 332 1.05E-25 T 31-10-2018 N186_06545 3a57389e21062c0a95e951af55722d24 335 Gene3D G3DSA:1.20.58.220 140 241 3.6E-13 T 31-10-2018 IPR038078 PhoU-like domain superfamily N186_02915 2771ca587d0b00ce36a11ab033982a3f 384 Gene3D G3DSA:3.40.50.150 5 323 1.5E-83 T 31-10-2018 N186_02915 2771ca587d0b00ce36a11ab033982a3f 384 SUPERFAMILY SSF53335 9 382 2.76E-92 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_02915 2771ca587d0b00ce36a11ab033982a3f 384 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 12 382 1.4E-95 T 31-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 N186_02915 2771ca587d0b00ce36a11ab033982a3f 384 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 30 382 1.9E-96 T 31-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 N186_02915 2771ca587d0b00ce36a11ab033982a3f 384 Gene3D G3DSA:3.30.56.70 325 384 3.7E-15 T 31-10-2018 N186_07830 9b99496e20ae24a44acf3e5a51e44e64 79 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 54 4.3E-12 T 31-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system N186_07830 9b99496e20ae24a44acf3e5a51e44e64 79 Gene3D G3DSA:3.30.160.250 1 63 7.0E-28 T 31-10-2018 N186_07830 9b99496e20ae24a44acf3e5a51e44e64 79 SUPERFAMILY SSF143100 2 53 1.57E-20 T 31-10-2018 IPR035069 TTHA1013/TTHA0281-like N186_04240 16e81e6dd55c9f82664c4e58ec1a0161 201 SUPERFAMILY SSF75217 17 200 7.15E-32 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases N186_04240 16e81e6dd55c9f82664c4e58ec1a0161 201 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 17 200 1.4E-20 T 31-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 N186_04240 16e81e6dd55c9f82664c4e58ec1a0161 201 Gene3D G3DSA:3.40.1280.10 11 201 3.4E-33 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal N186_06430 52ae883ab73d99ad040b3d2f85726614 108 ProDom PD012268 RIBOSOMAL S25 40S RIBONUCLEOPROTEIN S25 MULTIGENE FAMILY TRANSCRIPTION STRAIN DIRECT 46 105 2.0E-5 T 31-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_06430 52ae883ab73d99ad040b3d2f85726614 108 Pfam PF03297 S25 ribosomal protein 14 102 3.6E-15 T 31-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_06430 52ae883ab73d99ad040b3d2f85726614 108 Gene3D G3DSA:1.10.10.10 41 108 3.5E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_06430 52ae883ab73d99ad040b3d2f85726614 108 SUPERFAMILY SSF46785 44 93 2.97E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_06430 52ae883ab73d99ad040b3d2f85726614 108 Pfam PF11955 Plant organelle RNA recognition domain 6 78 1.0E-4 T 31-10-2018 IPR021099 Plant organelle RNA recognition domain N186_06275 8d3ae246b6f55e12dd6fc15c3e2cbe2d 247 SMART SM00849 25 219 9.7E-19 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_06275 8d3ae246b6f55e12dd6fc15c3e2cbe2d 247 Gene3D G3DSA:3.60.15.10 2 239 4.0E-42 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_06275 8d3ae246b6f55e12dd6fc15c3e2cbe2d 247 Pfam PF00753 Metallo-beta-lactamase superfamily 23 219 4.3E-17 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_06275 8d3ae246b6f55e12dd6fc15c3e2cbe2d 247 SUPERFAMILY SSF56281 23 242 1.96E-33 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_06645 561266f08f198390c1851e39ba46d169 429 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 222 237 - T 31-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 N186_06645 561266f08f198390c1851e39ba46d169 429 Pfam PF00120 Glutamine synthetase, catalytic domain 107 426 3.3E-75 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 N186_06645 561266f08f198390c1851e39ba46d169 429 SUPERFAMILY SSF54368 11 103 3.01E-12 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 N186_06645 561266f08f198390c1851e39ba46d169 429 Gene3D G3DSA:3.10.20.70 9 105 2.0E-9 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 N186_06645 561266f08f198390c1851e39ba46d169 429 SMART SM01230 104 340 6.7E-75 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 N186_06645 561266f08f198390c1851e39ba46d169 429 SUPERFAMILY SSF55931 105 427 1.37E-80 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 N186_06645 561266f08f198390c1851e39ba46d169 429 Gene3D G3DSA:3.30.590.10 107 428 5.3E-84 T 31-10-2018 N186_01600 18f8e5efe3fef54918bd9b8d1336aab2 512 Pfam PF03065 Glycosyl hydrolase family 57 2 331 1.6E-65 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 N186_01600 18f8e5efe3fef54918bd9b8d1336aab2 512 Gene3D G3DSA:3.20.110.20 37 335 1.7E-27 T 31-10-2018 N186_01600 18f8e5efe3fef54918bd9b8d1336aab2 512 SUPERFAMILY SSF88713 32 357 2.97E-61 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 N186_06855 90333e8343f6dadd6025c8a219c429dd 434 SUPERFAMILY SSF53850 43 425 8.98E-71 T 31-10-2018 N186_06855 90333e8343f6dadd6025c8a219c429dd 434 Gene3D G3DSA:3.40.190.10 152 422 1.2E-72 T 31-10-2018 N186_06855 90333e8343f6dadd6025c8a219c429dd 434 Pfam PF13416 Bacterial extracellular solute-binding protein 61 370 9.2E-34 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein N186_06855 90333e8343f6dadd6025c8a219c429dd 434 Gene3D G3DSA:3.40.190.10 63 383 1.2E-72 T 31-10-2018 N186_01345 b14d0de580158d39f36f1d1b6c287797 382 SUPERFAMILY SSF51161 225 373 6.99E-16 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily N186_01345 b14d0de580158d39f36f1d1b6c287797 382 Gene3D G3DSA:3.90.550.10 1 209 2.2E-14 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_01345 b14d0de580158d39f36f1d1b6c287797 382 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 242 274 2.9E-5 T 31-10-2018 IPR001451 Hexapeptide repeat N186_01345 b14d0de580158d39f36f1d1b6c287797 382 Gene3D G3DSA:2.160.10.10 210 377 1.1E-21 T 31-10-2018 N186_01345 b14d0de580158d39f36f1d1b6c287797 382 SUPERFAMILY SSF53448 1 298 1.3E-23 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_00470 2a9653096d79c89b5e2bd82ab5511e77 477 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 221 5.6E-34 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 N186_00470 2a9653096d79c89b5e2bd82ab5511e77 477 SUPERFAMILY SSF53067 6 240 9.16E-45 T 31-10-2018 N186_00470 2a9653096d79c89b5e2bd82ab5511e77 477 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 248 416 1.8E-29 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 N186_00470 2a9653096d79c89b5e2bd82ab5511e77 477 Gene3D G3DSA:3.30.420.40 2 233 3.4E-51 T 31-10-2018 N186_00470 2a9653096d79c89b5e2bd82ab5511e77 477 PIRSF PIRSF000538 3 477 6.3E-88 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 N186_00470 2a9653096d79c89b5e2bd82ab5511e77 477 SUPERFAMILY SSF53067 240 476 1.68E-44 T 31-10-2018 N186_00470 2a9653096d79c89b5e2bd82ab5511e77 477 Gene3D G3DSA:3.30.420.40 234 477 2.0E-56 T 31-10-2018 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Pfam PF00571 CBS domain 856 910 1.2E-10 T 31-10-2018 IPR000644 CBS domain N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Pfam PF00571 CBS domain 723 774 7.6E-11 T 31-10-2018 IPR000644 CBS domain N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Pfam PF00571 CBS domain 667 712 8.6E-7 T 31-10-2018 IPR000644 CBS domain N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Pfam PF00571 CBS domain 793 847 3.3E-7 T 31-10-2018 IPR000644 CBS domain N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Gene3D G3DSA:3.10.580.10 660 788 1.8E-25 T 31-10-2018 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 78 3.9E-15 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Gene3D G3DSA:3.10.580.10 789 911 1.9E-30 T 31-10-2018 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 617 2.8E-29 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Gene3D G3DSA:3.40.50.12780 52 524 1.9E-107 T 31-10-2018 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Gene3D G3DSA:3.30.300.30 526 657 3.6E-30 T 31-10-2018 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 SMART SM00116 668 714 1.4 T 31-10-2018 IPR000644 CBS domain N186_05780 453528fe5c70d30e64ccc788619c38f5 911 SMART SM00116 800 847 1.5E-5 T 31-10-2018 IPR000644 CBS domain N186_05780 453528fe5c70d30e64ccc788619c38f5 911 SMART SM00116 730 777 1.5E-6 T 31-10-2018 IPR000644 CBS domain N186_05780 453528fe5c70d30e64ccc788619c38f5 911 SMART SM00116 863 910 1.3E-10 T 31-10-2018 IPR000644 CBS domain N186_05780 453528fe5c70d30e64ccc788619c38f5 911 SUPERFAMILY SSF54631 660 775 3.23E-23 T 31-10-2018 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 31-10-2018 IPR020845 AMP-binding, conserved site N186_05780 453528fe5c70d30e64ccc788619c38f5 911 SUPERFAMILY SSF54631 791 910 7.68E-28 T 31-10-2018 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 Pfam PF00501 AMP-binding enzyme 88 530 9.1E-96 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 21 648 3.9E-281 T 31-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 N186_05780 453528fe5c70d30e64ccc788619c38f5 911 SUPERFAMILY SSF56801 24 642 1.05E-178 T 31-10-2018 N186_07360 07ca9d1345bc1521d6c30056fae76567 80 SMART SM00966 14 57 1.4E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_07360 07ca9d1345bc1521d6c30056fae76567 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 14 53 2.1E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_07360 07ca9d1345bc1521d6c30056fae76567 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 17 54 3.3E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_07360 07ca9d1345bc1521d6c30056fae76567 80 Gene3D G3DSA:2.10.260.10 11 52 3.5E-13 T 31-10-2018 N186_07360 07ca9d1345bc1521d6c30056fae76567 80 SUPERFAMILY SSF89447 7 53 2.27E-12 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_08475 077a68118f542738d0563792d86c7562 273 Gene3D G3DSA:3.40.50.1820 2 273 2.3E-68 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_08475 077a68118f542738d0563792d86c7562 273 PIRSF PIRSF017388 16 273 1.3E-28 T 31-10-2018 IPR012354 Esterase/lipase GO:0052689 N186_08475 077a68118f542738d0563792d86c7562 273 Pfam PF12146 Serine aminopeptidase, S33 24 256 4.4E-71 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 N186_08475 077a68118f542738d0563792d86c7562 273 SUPERFAMILY SSF53474 11 271 6.54E-47 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_08475 077a68118f542738d0563792d86c7562 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 4.0E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_08475 077a68118f542738d0563792d86c7562 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 4.0E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_08475 077a68118f542738d0563792d86c7562 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 212 226 4.0E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_07775 d0cb0fb68ebe518ecea19748d07c4ff0 446 Pfam PF13416 Bacterial extracellular solute-binding protein 73 367 5.3E-34 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein N186_07775 d0cb0fb68ebe518ecea19748d07c4ff0 446 SUPERFAMILY SSF53850 73 439 2.52E-51 T 31-10-2018 N186_07775 d0cb0fb68ebe518ecea19748d07c4ff0 446 Gene3D G3DSA:3.40.190.10 57 441 2.5E-50 T 31-10-2018 N186_03755 e221adcff375126580192467c8cc2a05 676 Gene3D G3DSA:3.40.50.300 248 527 1.5E-92 T 31-10-2018 N186_03755 e221adcff375126580192467c8cc2a05 676 Pfam PF00437 Type II/IV secretion system protein 149 407 5.8E-46 T 31-10-2018 IPR001482 Type II/IV secretion system protein N186_03755 e221adcff375126580192467c8cc2a05 676 Gene3D G3DSA:3.30.450.380 17 246 1.3E-68 T 31-10-2018 N186_03755 e221adcff375126580192467c8cc2a05 676 SUPERFAMILY SSF52540 129 439 3.29E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00990 352f62786f666cc7cdca8d3747f47822 399 Pfam PF00155 Aminotransferase class I and II 33 387 1.6E-62 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 N186_00990 352f62786f666cc7cdca8d3747f47822 399 Gene3D G3DSA:3.90.1150.10 24 393 2.8E-127 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 N186_00990 352f62786f666cc7cdca8d3747f47822 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 N186_00990 352f62786f666cc7cdca8d3747f47822 399 Gene3D G3DSA:3.40.640.10 52 295 2.8E-127 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 N186_00990 352f62786f666cc7cdca8d3747f47822 399 SUPERFAMILY SSF53383 4 396 3.63E-105 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase N186_02120 2ccff35217a1bd8eb5208722ec20ba0c 182 SUPERFAMILY SSF55282 12 176 1.27E-54 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02120 2ccff35217a1bd8eb5208722ec20ba0c 182 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 11 178 40.965 T 31-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02120 2ccff35217a1bd8eb5208722ec20ba0c 182 Pfam PF00281 Ribosomal protein L5 13 65 8.9E-19 T 31-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02120 2ccff35217a1bd8eb5208722ec20ba0c 182 Pfam PF00673 ribosomal L5P family C-terminus 69 168 1.1E-23 T 31-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02120 2ccff35217a1bd8eb5208722ec20ba0c 182 PIRSF PIRSF002161 1 177 6.2E-53 T 31-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02120 2ccff35217a1bd8eb5208722ec20ba0c 182 Gene3D G3DSA:3.30.1440.10 5 180 7.4E-69 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_00735 5ac10d1be955cb255a0f0c5c2808b34a 306 SUPERFAMILY SSF52096 26 243 2.44E-30 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily N186_00735 5ac10d1be955cb255a0f0c5c2808b34a 306 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 43 255 1.8E-48 T 31-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 N186_00735 5ac10d1be955cb255a0f0c5c2808b34a 306 Gene3D G3DSA:3.40.1750.20 150 213 9.9E-20 T 31-10-2018 N186_00735 5ac10d1be955cb255a0f0c5c2808b34a 306 Pfam PF01343 Peptidase family S49 109 256 2.2E-35 T 31-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 N186_00685 1fd7a425b7f83eb2ae6c83b6c408656d 252 SUPERFAMILY SSF69572 10 250 1.23E-94 T 31-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 N186_00685 1fd7a425b7f83eb2ae6c83b6c408656d 252 Pfam PF00899 ThiF family 18 245 3.1E-68 T 31-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 N186_00685 1fd7a425b7f83eb2ae6c83b6c408656d 252 Gene3D G3DSA:3.40.50.720 10 251 7.8E-88 T 31-10-2018 N186_04260 3ae15467d616fad30ab5742084ccadff 488 Gene3D G3DSA:2.40.380.10 325 467 4.6E-7 T 31-10-2018 IPR035930 FomD-like superfamily N186_04260 3ae15467d616fad30ab5742084ccadff 488 Pfam PF04167 Protein of unknown function (DUF402) 365 432 7.0E-9 T 31-10-2018 IPR007295 Domain of unknown function DUF402 N186_04260 3ae15467d616fad30ab5742084ccadff 488 SUPERFAMILY SSF159234 346 460 4.05E-11 T 31-10-2018 IPR035930 FomD-like superfamily N186_07700 571363564d44942aff6b9c167a27bd26 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 1.1E-8 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_07700 571363564d44942aff6b9c167a27bd26 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 176 195 1.1E-8 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_07700 571363564d44942aff6b9c167a27bd26 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 139 163 1.1E-8 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_07700 571363564d44942aff6b9c167a27bd26 255 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 247 1.7E-88 T 31-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein N186_07700 571363564d44942aff6b9c167a27bd26 255 Pfam PF01061 ABC-2 type transporter 4 216 3.8E-38 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 N186_07700 571363564d44942aff6b9c167a27bd26 255 PIRSF PIRSF006648 1 253 5.3E-64 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_09315 ef9ddf69ee26775a1c4df1ef7baf1c8a 323 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_09315 ef9ddf69ee26775a1c4df1ef7baf1c8a 323 Pfam PF00005 ABC transporter 31 181 6.0E-33 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09315 ef9ddf69ee26775a1c4df1ef7baf1c8a 323 SUPERFAMILY SSF52540 7 251 4.21E-75 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09315 ef9ddf69ee26775a1c4df1ef7baf1c8a 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 299 7.9E-22 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_09315 ef9ddf69ee26775a1c4df1ef7baf1c8a 323 SMART SM00382 39 238 6.9E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_09315 ef9ddf69ee26775a1c4df1ef7baf1c8a 323 Gene3D G3DSA:3.40.50.300 4 323 1.7E-101 T 31-10-2018 N186_09315 ef9ddf69ee26775a1c4df1ef7baf1c8a 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 319 4.8E-31 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_05130 7773769528ff4f0f1664be3e95b2fbf9 302 Pfam PF00294 pfkB family carbohydrate kinase 5 278 8.8E-45 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB N186_05130 7773769528ff4f0f1664be3e95b2fbf9 302 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 39 63 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 N186_05130 7773769528ff4f0f1664be3e95b2fbf9 302 Gene3D G3DSA:3.40.1190.20 2 292 3.5E-66 T 31-10-2018 IPR029056 Ribokinase-like N186_05130 7773769528ff4f0f1664be3e95b2fbf9 302 SUPERFAMILY SSF53613 2 288 1.56E-62 T 31-10-2018 IPR029056 Ribokinase-like N186_05130 7773769528ff4f0f1664be3e95b2fbf9 302 PRINTS PR00990 Ribokinase signature 7 28 1.1E-12 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 N186_05130 7773769528ff4f0f1664be3e95b2fbf9 302 PRINTS PR00990 Ribokinase signature 206 217 1.1E-12 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 N186_05130 7773769528ff4f0f1664be3e95b2fbf9 302 PRINTS PR00990 Ribokinase signature 176 191 1.1E-12 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 N186_05130 7773769528ff4f0f1664be3e95b2fbf9 302 PRINTS PR00990 Ribokinase signature 34 53 1.1E-12 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 N186_05130 7773769528ff4f0f1664be3e95b2fbf9 302 PRINTS PR00990 Ribokinase signature 105 118 1.1E-12 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 2.0E-13 T 31-10-2018 N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.0E-13 T 31-10-2018 N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.0E-13 T 31-10-2018 N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 2.0E-13 T 31-10-2018 N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 299 2.2E-49 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.4E-9 T 31-10-2018 N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.4E-9 T 31-10-2018 N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 1.4E-9 T 31-10-2018 N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 SUPERFAMILY SSF51905 3 311 2.73E-35 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_01975 8a3b77cf6b76d56c588e95d56c229427 390 Gene3D G3DSA:3.50.50.100 1 377 1.9E-80 T 31-10-2018 N186_07810 d44e7b5a75d1e4c77725ab9c4503eaf4 440 Gene3D G3DSA:3.40.50.300 25 159 3.4E-5 T 31-10-2018 N186_07810 d44e7b5a75d1e4c77725ab9c4503eaf4 440 SUPERFAMILY SSF52540 37 263 2.06E-15 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07810 d44e7b5a75d1e4c77725ab9c4503eaf4 440 Pfam PF13173 AAA domain 47 178 6.1E-25 T 31-10-2018 N186_04350 ee55849491041546e093ebcec774950f 255 Pfam PF00005 ABC transporter 21 180 1.2E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_04350 ee55849491041546e093ebcec774950f 255 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_04350 ee55849491041546e093ebcec774950f 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 231 252 7.4E-5 T 31-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal N186_04350 ee55849491041546e093ebcec774950f 255 SMART SM00382 30 245 4.1E-6 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04350 ee55849491041546e093ebcec774950f 255 SUPERFAMILY SSF52540 5 251 1.2E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04350 ee55849491041546e093ebcec774950f 255 Gene3D G3DSA:3.40.50.300 2 253 2.8E-66 T 31-10-2018 N186_00385 77069059c607016de3624419208393a3 366 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 141 6.6E-16 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 N186_00385 77069059c607016de3624419208393a3 366 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 N186_00385 77069059c607016de3624419208393a3 366 SMART SM00829 11 364 8.7E-4 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 N186_00385 77069059c607016de3624419208393a3 366 SUPERFAMILY SSF51735 152 324 4.21E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_00385 77069059c607016de3624419208393a3 366 Gene3D G3DSA:3.90.180.10 24 349 4.1E-115 T 31-10-2018 N186_00385 77069059c607016de3624419208393a3 366 Pfam PF00107 Zinc-binding dehydrogenase 189 281 5.4E-20 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 N186_00385 77069059c607016de3624419208393a3 366 SUPERFAMILY SSF50129 5 195 5.78E-47 T 31-10-2018 IPR011032 GroES-like superfamily N186_00385 77069059c607016de3624419208393a3 366 Gene3D G3DSA:3.40.50.720 174 304 4.1E-115 T 31-10-2018 N186_02960 145a818d20b6520ed2e7d85dfd2e2aff 160 SUPERFAMILY SSF55282 12 152 1.94E-35 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02960 145a818d20b6520ed2e7d85dfd2e2aff 160 Pfam PF01877 RNA binding 12 134 8.7E-36 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 N186_02960 145a818d20b6520ed2e7d85dfd2e2aff 160 Gene3D G3DSA:3.30.1440.10 6 152 2.6E-44 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_00305 a350b914baec69204ef32ecfc5bcb1e8 78 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 43 6.2E-19 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_00305 a350b914baec69204ef32ecfc5bcb1e8 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 3 47 1.3E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_00305 a350b914baec69204ef32ecfc5bcb1e8 78 SMART SM00966 3 50 3.4E-13 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_00305 a350b914baec69204ef32ecfc5bcb1e8 78 Gene3D G3DSA:2.10.260.10 2 43 1.0E-16 T 31-10-2018 N186_00305 a350b914baec69204ef32ecfc5bcb1e8 78 SUPERFAMILY SSF89447 3 61 1.12E-11 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_09360 7698a6184540b141d8df0f8f182fecdd 146 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 127 2.4E-33 T 31-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 N186_09360 7698a6184540b141d8df0f8f182fecdd 146 Gene3D G3DSA:3.40.1400.10 1 146 7.3E-40 T 31-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 N186_09360 7698a6184540b141d8df0f8f182fecdd 146 PIRSF PIRSF005384 1 146 4.2E-42 T 31-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 N186_09360 7698a6184540b141d8df0f8f182fecdd 146 Pfam PF02502 Ribose/Galactose Isomerase 3 134 1.8E-37 T 31-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 N186_09360 7698a6184540b141d8df0f8f182fecdd 146 SUPERFAMILY SSF89623 1 144 1.44E-39 T 31-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 N186_07535 cfa4885ab853af850a85057ece85e170 274 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 3 269 12.727 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07535 cfa4885ab853af850a85057ece85e170 274 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 132 158 3.4E-21 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07535 cfa4885ab853af850a85057ece85e170 274 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 184 212 3.4E-21 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07535 cfa4885ab853af850a85057ece85e170 274 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 114 132 3.4E-21 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07535 cfa4885ab853af850a85057ece85e170 274 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 9 36 3.4E-21 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07535 cfa4885ab853af850a85057ece85e170 274 Pfam PF00902 Sec-independent protein translocase protein (TatC) 17 252 2.0E-40 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_00675 14a555bfac3ff8c9d744e42a57faea05 246 SUPERFAMILY SSF47741 156 187 9.94E-5 T 31-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily N186_00675 14a555bfac3ff8c9d744e42a57faea05 246 Gene3D G3DSA:3.20.20.20 159 219 9.6E-8 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 N186_00675 14a555bfac3ff8c9d744e42a57faea05 246 SUPERFAMILY SSF52540 1 157 3.67E-12 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00675 14a555bfac3ff8c9d744e42a57faea05 246 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 127 4.1E-23 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 N186_00675 14a555bfac3ff8c9d744e42a57faea05 246 Gene3D G3DSA:3.40.50.300 1 158 1.3E-32 T 31-10-2018 N186_00675 14a555bfac3ff8c9d744e42a57faea05 246 Pfam PF04060 Putative Fe-S cluster 163 195 1.2E-10 T 31-10-2018 IPR007202 4Fe-4S domain GO:0051536 N186_00675 14a555bfac3ff8c9d744e42a57faea05 246 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 157 3.3E-30 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 N186_07465 d91a79ace82dc6b37d91d910323f5346 358 Gene3D G3DSA:2.40.50.140 279 315 1.6E-20 T 31-10-2018 N186_07465 d91a79ace82dc6b37d91d910323f5346 358 Gene3D G3DSA:3.40.50.300 2 221 4.0E-67 T 31-10-2018 N186_07465 d91a79ace82dc6b37d91d910323f5346 358 Pfam PF00005 ABC transporter 18 160 8.9E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_07465 d91a79ace82dc6b37d91d910323f5346 358 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_07465 d91a79ace82dc6b37d91d910323f5346 358 SUPERFAMILY SSF50331 236 350 1.56E-16 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal N186_07465 d91a79ace82dc6b37d91d910323f5346 358 SMART SM00382 27 211 4.6E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_07465 d91a79ace82dc6b37d91d910323f5346 358 Gene3D G3DSA:2.40.50.940 222 278 1.6E-20 T 31-10-2018 N186_07465 d91a79ace82dc6b37d91d910323f5346 358 SUPERFAMILY SSF52540 3 241 9.52E-85 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02105 aec4edba184d5a6219c972d1aa4cfbce 153 SUPERFAMILY SSF48140 5 142 6.15E-47 T 31-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02105 aec4edba184d5a6219c972d1aa4cfbce 153 SMART SM01416 5 145 2.2E-76 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02105 aec4edba184d5a6219c972d1aa4cfbce 153 Gene3D G3DSA:1.10.1650.10 4 56 1.1E-21 T 31-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02105 aec4edba184d5a6219c972d1aa4cfbce 153 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 5 148 26.204 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02105 aec4edba184d5a6219c972d1aa4cfbce 153 Gene3D G3DSA:1.10.1200.240 60 153 6.4E-22 T 31-10-2018 N186_02105 aec4edba184d5a6219c972d1aa4cfbce 153 Pfam PF01280 Ribosomal protein L19e 6 145 2.6E-50 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02220 eb22220a3d017aa2dde010b0abe641f0 370 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 361 40.493 T 31-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 N186_02220 eb22220a3d017aa2dde010b0abe641f0 370 Pfam PF13378 Enolase C-terminal domain-like 146 355 1.3E-39 T 31-10-2018 IPR029065 Enolase C-terminal domain-like N186_02220 eb22220a3d017aa2dde010b0abe641f0 370 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 125 3.3E-13 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain N186_02220 eb22220a3d017aa2dde010b0abe641f0 370 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 332 1.1E-102 T 31-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 N186_02220 eb22220a3d017aa2dde010b0abe641f0 370 Gene3D G3DSA:3.20.20.120 118 348 2.7E-120 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily N186_02220 eb22220a3d017aa2dde010b0abe641f0 370 SMART SM00922 143 235 1.0E-22 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal N186_02220 eb22220a3d017aa2dde010b0abe641f0 370 SUPERFAMILY SSF51604 115 365 1.11E-58 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily N186_02220 eb22220a3d017aa2dde010b0abe641f0 370 Gene3D G3DSA:3.30.390.10 7 352 2.7E-120 T 31-10-2018 IPR029017 Enolase-like, N-terminal N186_02220 eb22220a3d017aa2dde010b0abe641f0 370 SUPERFAMILY SSF54826 2 126 7.07E-31 T 31-10-2018 N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 Pfam PF00005 ABC transporter 21 173 2.1E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 Gene3D G3DSA:3.40.50.300 2 269 1.7E-67 T 31-10-2018 N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 Gene3D G3DSA:3.40.50.300 290 541 3.3E-70 T 31-10-2018 N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 Pfam PF00005 ABC transporter 309 454 6.2E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 SUPERFAMILY SSF52540 291 517 2.0E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 SUPERFAMILY SSF52540 3 237 6.07E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 SMART SM00382 318 503 7.3E-19 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 SMART SM00382 30 222 1.5E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_06745 8bbe45038ea1c22f7a0a3cb3b1062bba 541 ProSitePatterns PS00211 ABC transporters family signature. 427 441 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_02980 190f1f39551c0814cdf51af865e501fc 796 SUPERFAMILY SSF53098 17 407 6.33E-75 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily N186_02980 190f1f39551c0814cdf51af865e501fc 796 SMART SM00486 179 587 8.5E-104 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02980 190f1f39551c0814cdf51af865e501fc 796 ProSitePatterns PS00116 DNA polymerase family B signature. 575 583 - T 31-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02980 190f1f39551c0814cdf51af865e501fc 796 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 225 774 1.9E-78 T 31-10-2018 N186_02980 190f1f39551c0814cdf51af865e501fc 796 Gene3D G3DSA:3.90.1600.10 417 624 1.5E-58 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02980 190f1f39551c0814cdf51af865e501fc 796 Gene3D G3DSA:1.10.132.60 636 796 2.4E-46 T 31-10-2018 N186_02980 190f1f39551c0814cdf51af865e501fc 796 Pfam PF00136 DNA polymerase family B 373 774 2.4E-70 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02980 190f1f39551c0814cdf51af865e501fc 796 Pfam PF03104 DNA polymerase family B, exonuclease domain 40 306 1.2E-41 T 31-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02980 190f1f39551c0814cdf51af865e501fc 796 Gene3D G3DSA:1.10.287.690 484 537 1.5E-58 T 31-10-2018 N186_02980 190f1f39551c0814cdf51af865e501fc 796 SUPERFAMILY SSF56672 403 786 9.45E-114 T 31-10-2018 N186_02980 190f1f39551c0814cdf51af865e501fc 796 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 573 581 2.1E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02980 190f1f39551c0814cdf51af865e501fc 796 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 433 446 2.1E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02980 190f1f39551c0814cdf51af865e501fc 796 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 521 533 2.1E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_06690 5735064a6cb277dd54f29bb7e36d1b23 167 SUPERFAMILY SSF52728 8 156 5.23E-37 T 31-10-2018 IPR036667 Phosphotransferase system, sorbose subfamily IIB component superfamily GO:0005737|GO:0008982|GO:0009401 N186_06690 5735064a6cb277dd54f29bb7e36d1b23 167 Gene3D G3DSA:3.40.35.10 3 159 2.2E-41 T 31-10-2018 IPR036667 Phosphotransferase system, sorbose subfamily IIB component superfamily GO:0005737|GO:0008982|GO:0009401 N186_06690 5735064a6cb277dd54f29bb7e36d1b23 167 Pfam PF03830 PTS system sorbose subfamily IIB component 8 150 1.0E-39 T 31-10-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 N186_08555 9b18cb9e681cfefcf83f773ce9e52cc6 142 SUPERFAMILY SSF46785 13 111 2.01E-24 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_08555 9b18cb9e681cfefcf83f773ce9e52cc6 142 Pfam PF03551 Transcriptional regulator PadR-like family 17 85 5.6E-19 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal N186_08555 9b18cb9e681cfefcf83f773ce9e52cc6 142 Gene3D G3DSA:1.10.10.10 4 106 7.4E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_07290 32560082e525f73e648c761aba759cbb 348 PIRSF PIRSF004869 1 309 1.3E-58 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted N186_07290 32560082e525f73e648c761aba759cbb 348 SUPERFAMILY SSF102114 74 305 1.14E-24 T 31-10-2018 N186_07290 32560082e525f73e648c761aba759cbb 348 Gene3D G3DSA:3.20.20.70 77 312 1.9E-20 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_07290 32560082e525f73e648c761aba759cbb 348 Pfam PF04055 Radical SAM superfamily 81 225 1.8E-13 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_00885 774a437aad951f2772a4c3be05294e0e 279 SMART SM00382 31 221 2.0E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00885 774a437aad951f2772a4c3be05294e0e 279 Gene3D G3DSA:3.40.50.300 3 268 1.2E-65 T 31-10-2018 N186_00885 774a437aad951f2772a4c3be05294e0e 279 Pfam PF00005 ABC transporter 23 173 2.3E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00885 774a437aad951f2772a4c3be05294e0e 279 SUPERFAMILY SSF52540 5 236 1.39E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00885 774a437aad951f2772a4c3be05294e0e 279 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_07900 cc0612cba09ccb39bb729f6118103b69 338 Pfam PF01637 ATPase domain predominantly from Archaea 15 222 1.2E-52 T 31-10-2018 IPR011579 ATPase domain GO:0005524 N186_07900 cc0612cba09ccb39bb729f6118103b69 338 SUPERFAMILY SSF52540 12 229 5.72E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07900 cc0612cba09ccb39bb729f6118103b69 338 Gene3D G3DSA:3.40.50.300 5 178 5.4E-10 T 31-10-2018 N186_00440 7b17eafd5d271207505cd166390677a1 383 Pfam PF02687 FtsX-like permease family 282 376 1.7E-14 T 31-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 N186_00440 7b17eafd5d271207505cd166390677a1 383 Pfam PF12704 MacB-like periplasmic core domain 23 225 1.9E-14 T 31-10-2018 IPR025857 MacB-like periplasmic core domain N186_03240 7c2b1a5a9a80dda3519736593cb550a8 241 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 137 149 - T 31-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 N186_03240 7c2b1a5a9a80dda3519736593cb550a8 241 SUPERFAMILY SSF56112 20 179 7.82E-25 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily N186_03240 7c2b1a5a9a80dda3519736593cb550a8 241 Gene3D G3DSA:3.30.200.20 29 101 3.4E-18 T 31-10-2018 N186_03240 7c2b1a5a9a80dda3519736593cb550a8 241 Pfam PF00069 Protein kinase domain 21 168 2.9E-12 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 N186_03240 7c2b1a5a9a80dda3519736593cb550a8 241 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 26 228 2.9E-65 T 31-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 N186_03240 7c2b1a5a9a80dda3519736593cb550a8 241 SMART SM00220 18 234 0.0068 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 N186_03240 7c2b1a5a9a80dda3519736593cb550a8 241 SMART SM00090 1 184 0.0086 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 N186_03240 7c2b1a5a9a80dda3519736593cb550a8 241 Gene3D G3DSA:1.10.510.10 110 229 3.4E-31 T 31-10-2018 N186_07330 81dfa3a8881b26db681b30c4d6a2c902 349 PIRSF PIRSF000112 2 346 3.7E-68 T 31-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 N186_07330 81dfa3a8881b26db681b30c4d6a2c902 349 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 4 348 37.03 T 31-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 N186_07330 81dfa3a8881b26db681b30c4d6a2c902 349 Pfam PF13685 Iron-containing alcohol dehydrogenase 13 271 1.0E-66 T 31-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 N186_07330 81dfa3a8881b26db681b30c4d6a2c902 349 Gene3D G3DSA:1.20.1090.10 158 348 8.1E-53 T 31-10-2018 N186_07330 81dfa3a8881b26db681b30c4d6a2c902 349 Gene3D G3DSA:3.40.50.1970 2 156 3.0E-32 T 31-10-2018 N186_07330 81dfa3a8881b26db681b30c4d6a2c902 349 SUPERFAMILY SSF56796 6 344 5.89E-63 T 31-10-2018 N186_09560 1f255fc9b1b159b1b51222d90c54436d 434 Pfam PF09376 NurA domain 53 401 2.7E-16 T 31-10-2018 IPR018977 NurA domain N186_09560 1f255fc9b1b159b1b51222d90c54436d 434 SMART SM00933 52 402 7.7E-28 T 31-10-2018 IPR018977 NurA domain N186_07765 e9a38766005699421ffe6bbf1e84c6a1 695 Gene3D G3DSA:3.20.20.80 34 332 3.8E-7 T 31-10-2018 N186_07765 e9a38766005699421ffe6bbf1e84c6a1 695 SUPERFAMILY SSF52317 350 588 7.17E-14 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like N186_07765 e9a38766005699421ffe6bbf1e84c6a1 695 Pfam PF08532 Beta-galactosidase trimerisation domain 340 450 1.9E-9 T 31-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 N186_07765 e9a38766005699421ffe6bbf1e84c6a1 695 Gene3D G3DSA:3.40.50.880 336 566 8.0E-22 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like N186_07765 e9a38766005699421ffe6bbf1e84c6a1 695 SUPERFAMILY SSF51445 39 245 1.48E-5 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily N186_07765 e9a38766005699421ffe6bbf1e84c6a1 695 Pfam PF14871 Hypothetical glycosyl hydrolase 6 1 133 2.1E-33 T 31-10-2018 IPR028212 Hypothetical glycosyl hydrolase 6 N186_07765 e9a38766005699421ffe6bbf1e84c6a1 695 SUPERFAMILY SSF51445 2 171 4.79E-8 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily N186_07110 f965a144871f6587c471d63f9db673a0 239 Gene3D G3DSA:3.30.980.10 94 238 5.7E-28 T 31-10-2018 N186_07110 f965a144871f6587c471d63f9db673a0 239 Gene3D G3DSA:2.40.30.130 1 93 1.1E-20 T 31-10-2018 N186_07110 f965a144871f6587c471d63f9db673a0 239 SMART SM00863 193 235 1.5E-4 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 N186_07110 f965a144871f6587c471d63f9db673a0 239 SUPERFAMILY SSF50447 2 92 3.88E-17 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_07110 f965a144871f6587c471d63f9db673a0 239 Pfam PF01411 tRNA synthetases class II (A) 22 96 7.9E-15 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 N186_07110 f965a144871f6587c471d63f9db673a0 239 SUPERFAMILY SSF55186 94 227 5.36E-28 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 N186_07110 f965a144871f6587c471d63f9db673a0 239 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 194 225 5.3E-8 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 N186_05280 771121142b5bc19e1cea290ea6a308cb 152 SUPERFAMILY SSF55811 6 150 5.69E-25 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 N186_05280 771121142b5bc19e1cea290ea6a308cb 152 Pfam PF00293 NUDIX domain 6 122 2.5E-13 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 N186_05280 771121142b5bc19e1cea290ea6a308cb 152 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 N186_05280 771121142b5bc19e1cea290ea6a308cb 152 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 18 34 3.6E-17 T 31-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 N186_05280 771121142b5bc19e1cea290ea6a308cb 152 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 118 136 3.6E-17 T 31-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 N186_05280 771121142b5bc19e1cea290ea6a308cb 152 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 99 117 3.6E-17 T 31-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 N186_05280 771121142b5bc19e1cea290ea6a308cb 152 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 79 98 3.6E-17 T 31-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 N186_05280 771121142b5bc19e1cea290ea6a308cb 152 Gene3D G3DSA:3.90.79.10 2 151 2.6E-43 T 31-10-2018 N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 SUPERFAMILY SSF48019 225 318 3.06E-17 T 31-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 Gene3D G3DSA:3.40.50.300 1 160 6.4E-56 T 31-10-2018 N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 PRINTS PR00819 CbxX/CfqX superfamily signature 226 238 4.9E-5 T 31-10-2018 IPR000641 CbxX/CfqX GO:0005524 N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 PRINTS PR00819 CbxX/CfqX superfamily signature 39 54 4.9E-5 T 31-10-2018 IPR000641 CbxX/CfqX GO:0005524 N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 40 157 1.5E-14 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 SMART SM00382 36 164 3.7E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 Gene3D G3DSA:1.20.272.10 225 321 1.3E-26 T 31-10-2018 N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 Gene3D G3DSA:1.10.8.60 161 224 4.5E-20 T 31-10-2018 N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 Hamap MF_01509 Replication factor C small subunit [rfcS]. 2 319 48.925 T 31-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 SUPERFAMILY SSF52540 4 223 7.51E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02240 46a41b1bed88e7e7239550612d7f8d68 325 Pfam PF08542 Replication factor C C-terminal domain 225 314 6.8E-18 T 31-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 Pfam PF01479 S4 domain 55 93 3.5E-12 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 10 249 39.585 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 PIRSF PIRSF002116 4 251 2.6E-82 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 SUPERFAMILY SSF55174 55 112 1.23E-8 T 31-10-2018 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 Gene3D G3DSA:3.10.290.40 5 120 2.9E-41 T 31-10-2018 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 Gene3D G3DSA:2.40.50.740 125 184 9.2E-17 T 31-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 SMART SM00363 45 109 5.0E-6 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 Pfam PF08071 RS4NT (NUC023) domain 10 41 1.7E-14 T 31-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 Pfam PF00900 Ribosomal family S4e 99 178 1.9E-17 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 90 180 8.0E-14 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02125 832f2b14bd39487f343f71ecf0abfb2d 251 Gene3D G3DSA:2.30.30.30 186 251 1.4E-10 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 Gene3D G3DSA:3.40.50.300 96 302 1.4E-76 T 31-10-2018 N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 Gene3D G3DSA:1.20.120.140 5 88 4.1E-7 T 31-10-2018 N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 Pfam PF00448 SRP54-type protein, GTPase domain 109 301 9.3E-72 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 SMART SM00962 107 302 7.6E-98 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 28 301 2.2E-87 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 SMART SM00382 106 292 9.1E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 SUPERFAMILY SSF47364 7 86 1.78E-5 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 25 302 52.864 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 275 288 - T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 N186_03160 8981b17ae3758d0ae53d942cc17ddca2 302 SUPERFAMILY SSF52540 108 301 1.29E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07645 237fc73ad64d9b1b97138cbeb1159d8f 351 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 9 351 8.5E-97 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE N186_07645 237fc73ad64d9b1b97138cbeb1159d8f 351 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 325 2.0E-20 T 31-10-2018 IPR010918 PurM-like, C-terminal domain N186_07645 237fc73ad64d9b1b97138cbeb1159d8f 351 Gene3D G3DSA:3.30.1330.10 4 162 3.4E-39 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily N186_07645 237fc73ad64d9b1b97138cbeb1159d8f 351 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 161 5.8E-15 T 31-10-2018 IPR016188 PurM-like, N-terminal domain N186_07645 237fc73ad64d9b1b97138cbeb1159d8f 351 PIRSF PIRSF005644 4 351 1.3E-94 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE N186_07645 237fc73ad64d9b1b97138cbeb1159d8f 351 SUPERFAMILY SSF55326 11 164 1.24E-29 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily N186_07645 237fc73ad64d9b1b97138cbeb1159d8f 351 SUPERFAMILY SSF56042 168 342 7.18E-32 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily N186_07645 237fc73ad64d9b1b97138cbeb1159d8f 351 Gene3D G3DSA:3.90.650.10 167 351 1.4E-44 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily N186_02600 704a305ad07bfc4285de0a22cfd43146 774 Gene3D G3DSA:3.90.870.50 26 382 2.2E-142 T 31-10-2018 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 SUPERFAMILY SSF54975 19 109 2.4E-25 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 SUPERFAMILY SSF53067 452 770 3.67E-5 T 31-10-2018 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 ProSitePatterns PS00150 Acylphosphatase signature 1. 28 38 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 Pfam PF01300 Telomere recombination 230 403 5.6E-51 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 PIRSF PIRSF006256 19 773 2.7E-250 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 Pfam PF00708 Acylphosphatase 25 107 5.0E-22 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 Pfam PF07503 HypF finger 177 211 3.1E-16 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 Pfam PF07503 HypF finger 127 160 3.1E-14 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 Gene3D G3DSA:3.30.420.360 403 767 1.6E-83 T 31-10-2018 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 26 768 4.4E-234 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 Gene3D G3DSA:3.30.110.120 273 391 2.2E-142 T 31-10-2018 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 Gene3D G3DSA:3.30.420.350 509 756 1.6E-83 T 31-10-2018 N186_02600 704a305ad07bfc4285de0a22cfd43146 774 SUPERFAMILY SSF55821 197 414 4.27E-50 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily N186_08345 22aafe5ce2f283acd65bc073733e951e 481 Gene3D G3DSA:3.40.630.30 326 471 2.2E-10 T 31-10-2018 N186_08345 22aafe5ce2f283acd65bc073733e951e 481 PIRSF PIRSF005669 3 480 3.3E-208 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 N186_08345 22aafe5ce2f283acd65bc073733e951e 481 Gene3D G3DSA:3.80.30.20 31 292 1.0E-15 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe N186_08345 22aafe5ce2f283acd65bc073733e951e 481 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 12 478 8.5E-199 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 N186_08345 22aafe5ce2f283acd65bc073733e951e 481 Pfam PF04055 Radical SAM superfamily 32 228 1.5E-21 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_08345 22aafe5ce2f283acd65bc073733e951e 481 SMART SM00729 23 283 4.3E-49 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_08345 22aafe5ce2f283acd65bc073733e951e 481 SUPERFAMILY SSF55729 340 474 1.53E-11 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase N186_08345 22aafe5ce2f283acd65bc073733e951e 481 Pfam PF16199 Radical_SAM C-terminal domain 244 322 2.2E-28 T 31-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 N186_08345 22aafe5ce2f283acd65bc073733e951e 481 Pfam PF00583 Acetyltransferase (GNAT) family 358 466 1.1E-9 T 31-10-2018 IPR000182 GNAT domain N186_08345 22aafe5ce2f283acd65bc073733e951e 481 SUPERFAMILY SSF102114 32 290 1.44E-37 T 31-10-2018 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 SUPERFAMILY SSF64484 10 870 0.0 T 31-10-2018 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 SMART SM00663 211 516 4.1E-194 T 31-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Gene3D G3DSA:1.20.120.1280 3 124 6.0E-28 T 31-10-2018 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Gene3D G3DSA:1.20.120.1280 234 284 4.5E-11 T 31-10-2018 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Gene3D G3DSA:3.30.1490.180 354 419 1.5E-81 T 31-10-2018 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 488 5.2E-76 T 31-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Gene3D G3DSA:1.10.274.100 495 649 9.6E-95 T 31-10-2018 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Gene3D G3DSA:2.20.25.410 834 886 4.5E-21 T 31-10-2018 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Pfam PF04998 RNA polymerase Rpb1, domain 5 795 860 2.4E-24 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Pfam PF05000 RNA polymerase Rpb1, domain 4 683 788 6.6E-30 T 31-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Pfam PF04997 RNA polymerase Rpb1, domain 1 10 319 6.2E-94 T 31-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 10 878 0.0 T 31-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Gene3D G3DSA:1.10.132.30 650 796 9.6E-95 T 31-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Gene3D G3DSA:2.40.40.20 311 483 1.5E-81 T 31-10-2018 N186_02335 339118d06c5bdb27f7746f6545ff728a 890 Pfam PF04983 RNA polymerase Rpb1, domain 3 491 655 1.8E-38 T 31-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_03350 07fc2d11a7943669f151413873cf47a6 561 Pfam PF04055 Radical SAM superfamily 205 387 5.4E-17 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_03350 07fc2d11a7943669f151413873cf47a6 561 SUPERFAMILY SSF102114 186 424 4.32E-17 T 31-10-2018 N186_03350 07fc2d11a7943669f151413873cf47a6 561 Gene3D G3DSA:3.80.30.20 189 448 3.9E-18 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe N186_03350 07fc2d11a7943669f151413873cf47a6 561 SMART SM00729 189 435 1.1E-13 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_04395 70e345180dc9d753dcabae384d483289 191 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 9 185 2.7E-61 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 N186_04395 70e345180dc9d753dcabae384d483289 191 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 1 188 35.491 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 N186_04395 70e345180dc9d753dcabae384d483289 191 Pfam PF00347 Ribosomal protein L6 97 160 2.8E-9 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04395 70e345180dc9d753dcabae384d483289 191 Pfam PF00347 Ribosomal protein L6 12 85 1.3E-14 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04395 70e345180dc9d753dcabae384d483289 191 SUPERFAMILY SSF56053 86 162 1.44E-21 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04395 70e345180dc9d753dcabae384d483289 191 PIRSF PIRSF002162 1 174 7.3E-36 T 31-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04395 70e345180dc9d753dcabae384d483289 191 Gene3D G3DSA:3.90.930.12 1 85 1.2E-26 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04395 70e345180dc9d753dcabae384d483289 191 Gene3D G3DSA:3.90.930.12 86 189 1.1E-25 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04395 70e345180dc9d753dcabae384d483289 191 SUPERFAMILY SSF56053 4 85 5.04E-22 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02025 1f409799efb0518bca78ef4b8e59e958 584 SUPERFAMILY SSF160980 21 554 3.14E-26 T 31-10-2018 N186_02025 1f409799efb0518bca78ef4b8e59e958 584 Gene3D G3DSA:3.40.50.10640 20 300 2.2E-15 T 31-10-2018 N186_09070 b8d7bf48a4483be5e987d6b45b886195 383 Gene3D G3DSA:3.40.640.10 11 382 6.5E-96 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 N186_09070 b8d7bf48a4483be5e987d6b45b886195 383 Pfam PF00155 Aminotransferase class I and II 48 376 6.1E-55 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 N186_09070 b8d7bf48a4483be5e987d6b45b886195 383 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 222 235 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 N186_09070 b8d7bf48a4483be5e987d6b45b886195 383 SUPERFAMILY SSF53383 7 381 4.4E-92 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase N186_05055 bd8372e277298461d9f014a8d1dce1bd 299 SUPERFAMILY SSF46785 7 92 2.39E-19 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_05055 bd8372e277298461d9f014a8d1dce1bd 299 Pfam PF09202 Rio2, N-terminal 11 91 7.6E-21 T 31-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 N186_05055 bd8372e277298461d9f014a8d1dce1bd 299 Gene3D G3DSA:1.10.10.10 2 93 5.3E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_05055 bd8372e277298461d9f014a8d1dce1bd 299 Gene3D G3DSA:3.30.200.20 100 194 3.0E-32 T 31-10-2018 N186_05055 bd8372e277298461d9f014a8d1dce1bd 299 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 225 236 - T 31-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 N186_05055 bd8372e277298461d9f014a8d1dce1bd 299 Pfam PF01163 RIO1 family 110 286 3.8E-48 T 31-10-2018 N186_05055 bd8372e277298461d9f014a8d1dce1bd 299 Gene3D G3DSA:1.10.510.10 201 293 5.1E-25 T 31-10-2018 N186_05055 bd8372e277298461d9f014a8d1dce1bd 299 SMART SM00090 66 293 2.2E-52 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 N186_05055 bd8372e277298461d9f014a8d1dce1bd 299 SUPERFAMILY SSF56112 101 275 1.52E-28 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily N186_00585 92376a7fa5aebd54e273e360b768ad6d 393 Gene3D G3DSA:3.50.50.60 4 309 6.5E-81 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_00585 92376a7fa5aebd54e273e360b768ad6d 393 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 139 1.1E-11 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 N186_00585 92376a7fa5aebd54e273e360b768ad6d 393 SUPERFAMILY SSF51905 118 246 1.78E-23 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_00585 92376a7fa5aebd54e273e360b768ad6d 393 Gene3D G3DSA:3.50.50.60 107 255 6.5E-81 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_00585 92376a7fa5aebd54e273e360b768ad6d 393 SUPERFAMILY SSF51905 2 314 8.92E-28 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_05625 b3a2dce9349ad9593490ffaf45a76e7e 257 Gene3D G3DSA:3.60.15.10 2 249 2.0E-49 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_05625 b3a2dce9349ad9593490ffaf45a76e7e 257 SMART SM00849 19 190 0.0013 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_05625 b3a2dce9349ad9593490ffaf45a76e7e 257 SUPERFAMILY SSF56281 3 248 2.88E-46 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_05625 b3a2dce9349ad9593490ffaf45a76e7e 257 Pfam PF12706 Beta-lactamase superfamily domain 45 212 6.6E-17 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_05635 f52ce3171ce8c1c845d2af5c65f30edb 401 Gene3D G3DSA:3.40.50.720 200 352 4.0E-135 T 31-10-2018 N186_05635 f52ce3171ce8c1c845d2af5c65f30edb 401 SMART SM00829 39 399 4.9E-6 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 N186_05635 f52ce3171ce8c1c845d2af5c65f30edb 401 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 56 177 1.1E-28 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 N186_05635 f52ce3171ce8c1c845d2af5c65f30edb 401 Pfam PF00107 Zinc-binding dehydrogenase 228 350 6.9E-21 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 N186_05635 f52ce3171ce8c1c845d2af5c65f30edb 401 Gene3D G3DSA:3.90.180.10 5 362 4.0E-135 T 31-10-2018 N186_05635 f52ce3171ce8c1c845d2af5c65f30edb 401 SUPERFAMILY SSF50129 35 227 3.96E-43 T 31-10-2018 IPR011032 GroES-like superfamily N186_05635 f52ce3171ce8c1c845d2af5c65f30edb 401 SUPERFAMILY SSF51735 193 366 1.31E-36 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_05635 f52ce3171ce8c1c845d2af5c65f30edb 401 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 97 111 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 N186_08925 01d4c5609166b172f5f086f57829846d 634 Gene3D G3DSA:3.90.228.20 259 611 1.0E-144 T 31-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 N186_08925 01d4c5609166b172f5f086f57829846d 634 Gene3D G3DSA:2.170.8.10 77 410 1.0E-144 T 31-10-2018 N186_08925 01d4c5609166b172f5f086f57829846d 634 SUPERFAMILY SSF53795 256 616 1.42E-108 T 31-10-2018 N186_08925 01d4c5609166b172f5f086f57829846d 634 Gene3D G3DSA:3.40.449.10 43 258 1.0E-144 T 31-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 N186_08925 01d4c5609166b172f5f086f57829846d 634 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 256 613 1.8E-107 T 31-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 N186_08925 01d4c5609166b172f5f086f57829846d 634 SUPERFAMILY SSF68923 25 254 3.35E-53 T 31-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 N186_08925 01d4c5609166b172f5f086f57829846d 634 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 30 616 32.699 T 31-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 N186_08925 01d4c5609166b172f5f086f57829846d 634 PIRSF PIRSF001348 18 619 2.7E-171 T 31-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 N186_08925 01d4c5609166b172f5f086f57829846d 634 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 43 251 5.4E-57 T 31-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 N186_06975 c465e7e24afeb3e73a98e660d65db075 235 SMART SM00934 18 226 6.8E-26 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06975 c465e7e24afeb3e73a98e660d65db075 235 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 38 226 1.3E-15 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06975 c465e7e24afeb3e73a98e660d65db075 235 Gene3D G3DSA:3.20.20.70 15 234 7.1E-42 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_06975 c465e7e24afeb3e73a98e660d65db075 235 SUPERFAMILY SSF51366 11 233 8.54E-38 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 N186_06825 92b3168310479eb35717f48518d74903 115 SUPERFAMILY SSF81343 9 111 3.6E-15 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 N186_06825 92b3168310479eb35717f48518d74903 115 Gene3D G3DSA:1.20.1300.10 1 115 2.0E-12 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 N186_06825 92b3168310479eb35717f48518d74903 115 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 9 105 6.5E-11 T 31-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 N186_09065 db05ce60a4ec742f527738a6ad0b212b 278 Pfam PF00005 ABC transporter 25 170 4.8E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09065 db05ce60a4ec742f527738a6ad0b212b 278 SUPERFAMILY SSF52540 7 235 1.93E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09065 db05ce60a4ec742f527738a6ad0b212b 278 SMART SM00382 34 219 4.9E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_09065 db05ce60a4ec742f527738a6ad0b212b 278 Gene3D G3DSA:3.40.50.300 4 277 1.9E-67 T 31-10-2018 N186_00760 87a006e294167aaa05504f11d3dcd4d3 125 SUPERFAMILY SSF49367 17 122 1.57E-26 T 31-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 N186_00760 87a006e294167aaa05504f11d3dcd4d3 125 Gene3D G3DSA:2.60.40.730 2 125 1.5E-43 T 31-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 N186_00760 87a006e294167aaa05504f11d3dcd4d3 125 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 22 123 1.9E-18 T 31-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 N186_00760 87a006e294167aaa05504f11d3dcd4d3 125 Pfam PF01880 Desulfoferrodoxin 21 118 1.2E-29 T 31-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 N186_04160 60d550c30d9868db0e7e60747e134b9c 298 Gene3D G3DSA:3.40.50.970 64 298 1.1E-69 T 31-10-2018 N186_04160 60d550c30d9868db0e7e60747e134b9c 298 SUPERFAMILY SSF52518 3 297 1.74E-82 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold N186_04160 60d550c30d9868db0e7e60747e134b9c 298 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 55 201 1.7E-23 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 N186_08860 af226d8c2fada5b7b263d36e8c51757b 134 SUPERFAMILY SSF88723 1 121 2.8E-17 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_08860 af226d8c2fada5b7b263d36e8c51757b 134 Gene3D G3DSA:3.40.50.1010 1 132 1.9E-12 T 31-10-2018 N186_08860 af226d8c2fada5b7b263d36e8c51757b 134 Pfam PF01850 PIN domain 1 122 2.7E-10 T 31-10-2018 IPR002716 PIN domain N186_08860 af226d8c2fada5b7b263d36e8c51757b 134 SMART SM00670 1 120 1.4E-4 T 31-10-2018 IPR002716 PIN domain N186_08635 b0bf65cc6ed5f15741f40c02e5fbdaa5 140 Gene3D G3DSA:3.40.50.1010 6 137 1.7E-7 T 31-10-2018 N186_08635 b0bf65cc6ed5f15741f40c02e5fbdaa5 140 SUPERFAMILY SSF88723 8 132 3.36E-13 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_08635 b0bf65cc6ed5f15741f40c02e5fbdaa5 140 Pfam PF01850 PIN domain 8 131 3.8E-10 T 31-10-2018 IPR002716 PIN domain N186_00445 ec2dd26add0aeec527a57da2aea68db0 298 SUPERFAMILY SSF52540 6 235 2.52E-71 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00445 ec2dd26add0aeec527a57da2aea68db0 298 Pfam PF00005 ABC transporter 25 174 6.6E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00445 ec2dd26add0aeec527a57da2aea68db0 298 Gene3D G3DSA:3.40.50.300 4 286 5.2E-71 T 31-10-2018 N186_00445 ec2dd26add0aeec527a57da2aea68db0 298 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_00445 ec2dd26add0aeec527a57da2aea68db0 298 SMART SM00382 34 230 8.3E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_08440 9e6d006c864809eb5e187187f46c3f9a 200 Pfam PF00037 4Fe-4S binding domain 9 25 1.0E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_08440 9e6d006c864809eb5e187187f46c3f9a 200 Pfam PF13247 4Fe-4S dicluster domain 66 161 2.5E-27 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_08440 9e6d006c864809eb5e187187f46c3f9a 200 SUPERFAMILY SSF54862 3 197 9.42E-71 T 31-10-2018 N186_08440 9e6d006c864809eb5e187187f46c3f9a 200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 106 117 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_08440 9e6d006c864809eb5e187187f46c3f9a 200 Gene3D G3DSA:3.30.70.20 2 40 3.3E-7 T 31-10-2018 N186_08440 9e6d006c864809eb5e187187f46c3f9a 200 Gene3D G3DSA:3.30.70.20 41 200 3.2E-64 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 Gene3D G3DSA:3.40.50.620 205 403 3.2E-61 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 Pfam PF00958 GMP synthase C terminal domain 431 522 4.5E-41 T 31-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 Gene3D G3DSA:3.40.50.880 3 201 6.8E-56 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 SUPERFAMILY SSF54810 403 523 2.48E-49 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 209 523 8.8E-121 T 31-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 PRINTS PR00097 Anthranilate synthase component II signature 173 186 1.6E-7 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 PRINTS PR00097 Anthranilate synthase component II signature 54 63 1.6E-7 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 PRINTS PR00097 Anthranilate synthase component II signature 85 96 1.6E-7 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 3.9E-9 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 3.9E-9 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 PRINTS PR00096 Glutamine amidotransferase superfamily signature 85 96 3.9E-9 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 SUPERFAMILY SSF52402 189 444 9.54E-48 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 3.3E-5 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 85 101 3.3E-5 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 3.3E-5 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 199 2.8E-69 T 31-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 Pfam PF00117 Glutamine amidotransferase class-I 12 195 9.5E-40 T 31-10-2018 IPR017926 Glutamine amidotransferase N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 Gene3D G3DSA:3.30.300.10 404 523 4.2E-52 T 31-10-2018 N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 SUPERFAMILY SSF52317 9 204 2.07E-53 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like N186_05175 e203a7c0b5d4ff13876421dbc9a3982c 523 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 523 45.602 T 31-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 N186_05845 e87424bc278ead37b259c68ce57f07d5 214 Gene3D G3DSA:3.30.1360.160 112 195 1.3E-7 T 31-10-2018 N186_05845 e87424bc278ead37b259c68ce57f07d5 214 Gene3D G3DSA:1.20.120.1220 5 209 1.3E-7 T 31-10-2018 N186_05845 e87424bc278ead37b259c68ce57f07d5 214 Pfam PF01478 Type IV leader peptidase family 1 95 2.4E-6 T 31-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 N186_01850 eaebed1c1c06d68974b8de7a37ea706c 246 PIRSF PIRSF005902 1 246 6.3E-48 T 31-10-2018 IPR001130 TatD family GO:0016788 N186_01850 eaebed1c1c06d68974b8de7a37ea706c 246 Gene3D G3DSA:3.20.20.140 1 246 4.7E-56 T 31-10-2018 N186_01850 eaebed1c1c06d68974b8de7a37ea706c 246 Pfam PF01026 TatD related DNase 4 242 3.1E-49 T 31-10-2018 IPR001130 TatD family GO:0016788 N186_01850 eaebed1c1c06d68974b8de7a37ea706c 246 SUPERFAMILY SSF51556 3 243 3.23E-51 T 31-10-2018 IPR032466 Metal-dependent hydrolase N186_03305 4e1f17e10eb73c8b708f448e4a12119a 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 1.3E-11 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_03305 4e1f17e10eb73c8b708f448e4a12119a 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 1.3E-11 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_03305 4e1f17e10eb73c8b708f448e4a12119a 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 1.3E-11 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_03305 4e1f17e10eb73c8b708f448e4a12119a 107 SMART SM00418 14 92 3.8E-20 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_03305 4e1f17e10eb73c8b708f448e4a12119a 107 Pfam PF01022 Bacterial regulatory protein, arsR family 21 66 1.9E-12 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_03305 4e1f17e10eb73c8b708f448e4a12119a 107 SUPERFAMILY SSF46785 9 105 3.71E-23 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_03305 4e1f17e10eb73c8b708f448e4a12119a 107 Gene3D G3DSA:1.10.10.10 2 103 1.1E-25 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_03795 38d03df0f73a014399473c56f6920592 432 Pfam PF02881 SRP54-type protein, helical bundle domain 5 81 4.2E-14 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 N186_03795 38d03df0f73a014399473c56f6920592 432 SUPERFAMILY SSF47446 306 420 8.37E-29 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 N186_03795 38d03df0f73a014399473c56f6920592 432 Gene3D G3DSA:3.40.50.300 89 283 4.3E-104 T 31-10-2018 N186_03795 38d03df0f73a014399473c56f6920592 432 SUPERFAMILY SSF47364 2 89 6.15E-20 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 N186_03795 38d03df0f73a014399473c56f6920592 432 SUPERFAMILY SSF52540 97 295 1.63E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03795 38d03df0f73a014399473c56f6920592 432 SMART SM00962 99 294 7.7E-90 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 N186_03795 38d03df0f73a014399473c56f6920592 432 Gene3D G3DSA:1.10.260.30 307 428 1.8E-34 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 N186_03795 38d03df0f73a014399473c56f6920592 432 SMART SM00963 4 85 8.7E-14 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 N186_03795 38d03df0f73a014399473c56f6920592 432 Gene3D G3DSA:1.20.120.140 6 302 4.3E-104 T 31-10-2018 N186_03795 38d03df0f73a014399473c56f6920592 432 Pfam PF00448 SRP54-type protein, GTPase domain 101 294 9.5E-68 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 N186_03795 38d03df0f73a014399473c56f6920592 432 Pfam PF02978 Signal peptide binding domain 324 417 1.2E-25 T 31-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 N186_03795 38d03df0f73a014399473c56f6920592 432 SMART SM00382 98 239 6.6E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_03795 38d03df0f73a014399473c56f6920592 432 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 4 432 32.449 T 31-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 N186_00755 f9e8bd3a1112fac9186d36494ad112ef 293 SUPERFAMILY SSF53448 4 277 1.69E-60 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_00755 f9e8bd3a1112fac9186d36494ad112ef 293 Pfam PF00483 Nucleotidyl transferase 4 270 3.4E-33 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 N186_00755 f9e8bd3a1112fac9186d36494ad112ef 293 Gene3D G3DSA:3.90.550.10 1 292 3.3E-76 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_02310 68887150a34580d166c5d49e2c3261b2 290 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 5 277 28.217 T 31-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02310 68887150a34580d166c5d49e2c3261b2 290 Gene3D G3DSA:2.170.120.12 42 165 6.3E-80 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02310 68887150a34580d166c5d49e2c3261b2 290 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 19 267 4.5E-15 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02310 68887150a34580d166c5d49e2c3261b2 290 Gene3D G3DSA:3.30.1360.10 15 271 6.3E-80 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02310 68887150a34580d166c5d49e2c3261b2 290 SUPERFAMILY SSF55257 4 277 6.08E-28 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02310 68887150a34580d166c5d49e2c3261b2 290 Gene3D G3DSA:3.30.70.20 176 238 6.3E-80 T 31-10-2018 N186_02310 68887150a34580d166c5d49e2c3261b2 290 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 48 166 6.9E-23 T 31-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02310 68887150a34580d166c5d49e2c3261b2 290 SUPERFAMILY SSF56553 41 167 1.01E-28 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02310 68887150a34580d166c5d49e2c3261b2 290 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 30 70 - T 31-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 N186_02310 68887150a34580d166c5d49e2c3261b2 290 SMART SM00662 16 274 1.1E-64 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_01670 b586d8747a91efeed1ddb21f786da38f 897 Gene3D G3DSA:3.40.190.10 32 347 8.0E-25 T 31-10-2018 N186_01670 b586d8747a91efeed1ddb21f786da38f 897 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 32 270 2.6E-20 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain N186_01670 b586d8747a91efeed1ddb21f786da38f 897 SUPERFAMILY SSF53850 29 347 1.05E-32 T 31-10-2018 N186_01670 b586d8747a91efeed1ddb21f786da38f 897 Gene3D G3DSA:3.10.105.10 89 336 8.0E-25 T 31-10-2018 N186_08080 881882cec6bf8e47a5c4e5ac5c324151 152 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 132 9.467 T 31-10-2018 IPR022907 VapC family GO:0004540 N186_08080 881882cec6bf8e47a5c4e5ac5c324151 152 SUPERFAMILY SSF88723 6 130 1.09E-18 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_08080 881882cec6bf8e47a5c4e5ac5c324151 152 Gene3D G3DSA:3.40.50.1010 5 132 2.9E-9 T 31-10-2018 N186_08080 881882cec6bf8e47a5c4e5ac5c324151 152 Pfam PF01850 PIN domain 6 121 1.2E-13 T 31-10-2018 IPR002716 PIN domain N186_07175 cae16ba8fe35166820a35375441598fd 470 Pfam PF01458 Uncharacterized protein family (UPF0051) 214 439 5.9E-64 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 N186_07175 cae16ba8fe35166820a35375441598fd 470 SUPERFAMILY SSF101960 36 463 4.18E-118 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily N186_07175 cae16ba8fe35166820a35375441598fd 470 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 23 458 1.7E-184 T 31-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 N186_07575 315c5fe4526d16a7a647fb0c8e58f9ec 530 Gene3D G3DSA:3.10.105.10 284 504 1.0E-118 T 31-10-2018 N186_07575 315c5fe4526d16a7a647fb0c8e58f9ec 530 SUPERFAMILY SSF53850 35 527 4.52E-124 T 31-10-2018 N186_07575 315c5fe4526d16a7a647fb0c8e58f9ec 530 Gene3D G3DSA:3.40.190.10 201 513 1.0E-118 T 31-10-2018 N186_07575 315c5fe4526d16a7a647fb0c8e58f9ec 530 PIRSF PIRSF002741 4 528 1.1E-93 T 31-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 N186_07575 315c5fe4526d16a7a647fb0c8e58f9ec 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 450 1.8E-89 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain N186_07575 315c5fe4526d16a7a647fb0c8e58f9ec 530 Gene3D G3DSA:3.90.76.10 55 200 1.0E-118 T 31-10-2018 N186_06610 8ef75247f2921e033082c58319f5808b 340 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 218 231 - T 31-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06610 8ef75247f2921e033082c58319f5808b 340 Pfam PF00146 NADH dehydrogenase 30 330 3.6E-80 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06610 8ef75247f2921e033082c58319f5808b 340 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 5 338 18.625 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_03580 2ad98b4c3c822338db582ca075eb3652 370 SUPERFAMILY SSF52540 124 363 3.34E-37 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03580 2ad98b4c3c822338db582ca075eb3652 370 Gene3D G3DSA:3.40.50.300 121 358 5.0E-52 T 31-10-2018 N186_03580 2ad98b4c3c822338db582ca075eb3652 370 Pfam PF06745 KaiC 126 359 1.3E-65 T 31-10-2018 IPR014774 KaiC-like domain N186_08330 131d824ccf71ecd4ee9cbd595f61e4a2 491 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 268 487 9.4E-16 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_08330 131d824ccf71ecd4ee9cbd595f61e4a2 491 Gene3D G3DSA:1.10.3720.10 233 487 1.3E-52 T 31-10-2018 IPR035906 MetI-like superfamily N186_08330 131d824ccf71ecd4ee9cbd595f61e4a2 491 SUPERFAMILY SSF161098 237 476 4.06E-43 T 31-10-2018 IPR035906 MetI-like superfamily N186_08330 131d824ccf71ecd4ee9cbd595f61e4a2 491 SUPERFAMILY SSF160964 10 118 8.24E-7 T 31-10-2018 N186_03150 be103ec6142a3dd124922e88be30398c 332 SUPERFAMILY SSF56281 27 257 8.57E-8 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_03150 be103ec6142a3dd124922e88be30398c 332 PIRSF PIRSF004944 11 320 4.9E-82 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase N186_03150 be103ec6142a3dd124922e88be30398c 332 Pfam PF13483 Beta-lactamase superfamily domain 33 226 5.5E-5 T 31-10-2018 N186_03150 be103ec6142a3dd124922e88be30398c 332 Hamap MF_01406 UPF0282 protein . 11 301 34.491 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase N186_03150 be103ec6142a3dd124922e88be30398c 332 Gene3D G3DSA:3.60.15.10 14 270 1.1E-7 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 230 251 1.4E-51 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 57 67 1.4E-51 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 137 1.4E-51 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.4E-51 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 264 282 1.4E-51 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 1.4E-51 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 37 52 1.4E-51 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 164 1.4E-51 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 192 208 1.4E-51 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_01050 4ff01d65a655e823103916b36ceaa304 335 Gene3D G3DSA:3.50.50.60 4 295 9.3E-100 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_01050 4ff01d65a655e823103916b36ceaa304 335 SUPERFAMILY SSF51905 1 304 5.81E-46 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_01050 4ff01d65a655e823103916b36ceaa304 335 Gene3D G3DSA:3.50.50.60 114 236 9.3E-100 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.7E-28 T 31-10-2018 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 4.7E-28 T 31-10-2018 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 4.7E-28 T 31-10-2018 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 4.7E-28 T 31-10-2018 N186_01050 4ff01d65a655e823103916b36ceaa304 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 4.7E-28 T 31-10-2018 N186_01050 4ff01d65a655e823103916b36ceaa304 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 288 4.2E-40 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 N186_06990 d2511cb77bff5dbe751a1981e337ca1b 157 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 101 150 3.4E-18 T 31-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal N186_06990 d2511cb77bff5dbe751a1981e337ca1b 157 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 6 97 1.0E-34 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal N186_06990 d2511cb77bff5dbe751a1981e337ca1b 157 Gene3D G3DSA:3.30.70.140 1 98 4.7E-39 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily N186_06990 d2511cb77bff5dbe751a1981e337ca1b 157 SUPERFAMILY SSF57825 101 154 6.67E-15 T 31-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily N186_06990 d2511cb77bff5dbe751a1981e337ca1b 157 Gene3D G3DSA:2.30.30.20 99 157 7.0E-20 T 31-10-2018 N186_06990 d2511cb77bff5dbe751a1981e337ca1b 157 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 2 152 35.095 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 N186_06990 d2511cb77bff5dbe751a1981e337ca1b 157 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 7 98 2.0E-27 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal N186_06990 d2511cb77bff5dbe751a1981e337ca1b 157 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 3 151 1.0E-57 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 N186_06990 d2511cb77bff5dbe751a1981e337ca1b 157 SUPERFAMILY SSF54893 2 99 2.35E-34 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily N186_00490 66dcea0d1fe37485812dfd2dff33c840 360 SUPERFAMILY SSF50331 265 355 6.8E-12 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal N186_00490 66dcea0d1fe37485812dfd2dff33c840 360 SMART SM00382 30 213 4.9E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00490 66dcea0d1fe37485812dfd2dff33c840 360 Gene3D G3DSA:3.40.50.300 4 223 5.2E-63 T 31-10-2018 N186_00490 66dcea0d1fe37485812dfd2dff33c840 360 Gene3D G3DSA:2.40.50.140 292 349 4.6E-12 T 31-10-2018 N186_00490 66dcea0d1fe37485812dfd2dff33c840 360 SUPERFAMILY SSF52540 5 243 5.32E-84 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00490 66dcea0d1fe37485812dfd2dff33c840 360 Pfam PF00005 ABC transporter 26 163 1.6E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00490 66dcea0d1fe37485812dfd2dff33c840 360 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_00490 66dcea0d1fe37485812dfd2dff33c840 360 Gene3D G3DSA:2.40.50.940 224 354 4.6E-12 T 31-10-2018 N186_00490 66dcea0d1fe37485812dfd2dff33c840 360 Pfam PF08402 TOBE domain 285 355 6.3E-9 T 31-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 N186_00210 489f28e1e7576f5f51b090f70ad38d45 137 SUPERFAMILY SSF88723 3 135 7.85E-17 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_00210 489f28e1e7576f5f51b090f70ad38d45 137 Gene3D G3DSA:3.40.50.1010 2 130 4.2E-27 T 31-10-2018 N186_00210 489f28e1e7576f5f51b090f70ad38d45 137 Pfam PF01850 PIN domain 3 126 1.3E-11 T 31-10-2018 IPR002716 PIN domain N186_02530 b6929ca40a2a4a6ca9191895f230e8c3 269 SUPERFAMILY SSF54534 4 153 3.93E-31 T 31-10-2018 N186_02530 b6929ca40a2a4a6ca9191895f230e8c3 269 Gene3D G3DSA:3.10.50.40 5 149 1.7E-42 T 31-10-2018 N186_02530 b6929ca40a2a4a6ca9191895f230e8c3 269 Gene3D G3DSA:3.30.70.2210 155 239 1.3E-7 T 31-10-2018 N186_02530 b6929ca40a2a4a6ca9191895f230e8c3 269 Gene3D G3DSA:2.40.10.330 93 136 1.7E-42 T 31-10-2018 N186_02530 b6929ca40a2a4a6ca9191895f230e8c3 269 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 100 2.9E-7 T 31-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 178 197 3.1E-31 T 31-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 260 279 3.1E-31 T 31-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 55 76 3.1E-31 T 31-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 307 333 3.1E-31 T 31-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 39 55 3.1E-31 T 31-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 98 111 3.1E-31 T 31-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 82 96 3.1E-31 T 31-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 129 145 3.1E-31 T 31-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 SUPERFAMILY SSF53850 36 340 5.67E-79 T 31-10-2018 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 Pfam PF13416 Bacterial extracellular solute-binding protein 49 325 1.2E-35 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 PIRSF PIRSF019574 1 360 5.7E-113 T 31-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 Gene3D G3DSA:3.40.190.10 138 333 2.1E-101 T 31-10-2018 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 Gene3D G3DSA:3.40.190.10 38 329 2.1E-101 T 31-10-2018 N186_06115 7e885694deb5ad9d1546a02c8a1deb42 360 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 26 7.4E-4 T 31-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal N186_06085 4eb7345386cce9b2fdcb784a0d3247d3 246 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_06085 4eb7345386cce9b2fdcb784a0d3247d3 246 Pfam PF00005 ABC transporter 23 170 5.4E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_06085 4eb7345386cce9b2fdcb784a0d3247d3 246 PIRSF PIRSF039085 3 246 9.7E-87 T 31-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 N186_06085 4eb7345386cce9b2fdcb784a0d3247d3 246 Gene3D G3DSA:3.40.50.300 4 246 6.2E-78 T 31-10-2018 N186_06085 4eb7345386cce9b2fdcb784a0d3247d3 246 SMART SM00382 31 218 1.3E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_06085 4eb7345386cce9b2fdcb784a0d3247d3 246 SUPERFAMILY SSF52540 7 240 6.69E-76 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08195 551c36ff29d4df16c8a54ad65094c646 344 SUPERFAMILY SSF53448 2 259 3.09E-38 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_08195 551c36ff29d4df16c8a54ad65094c646 344 Gene3D G3DSA:3.90.550.10 2 233 8.9E-34 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_08195 551c36ff29d4df16c8a54ad65094c646 344 Pfam PF00535 Glycosyl transferase family 2 8 181 9.4E-22 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 N186_04485 efb556a4b796206a5232273b51b7c8c3 211 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 28 196 8.7E-54 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 N186_04485 efb556a4b796206a5232273b51b7c8c3 211 SUPERFAMILY SSF52540 26 199 4.04E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04485 efb556a4b796206a5232273b51b7c8c3 211 Gene3D G3DSA:3.40.50.300 15 199 4.9E-38 T 31-10-2018 N186_04485 efb556a4b796206a5232273b51b7c8c3 211 Pfam PF13189 Cytidylate kinase-like family 29 180 2.3E-21 T 31-10-2018 N186_04485 efb556a4b796206a5232273b51b7c8c3 211 Hamap MF_00239 Cytidylate kinase [cmk]. 27 200 39.629 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 N186_02975 c0e95d5210623af0530050b7724fc6c0 205 PRINTS PR00141 Proteasome component signature 170 181 7.3E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02975 c0e95d5210623af0530050b7724fc6c0 205 PRINTS PR00141 Proteasome component signature 13 28 7.3E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02975 c0e95d5210623af0530050b7724fc6c0 205 PRINTS PR00141 Proteasome component signature 145 156 7.3E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02975 c0e95d5210623af0530050b7724fc6c0 205 PRINTS PR00141 Proteasome component signature 134 145 7.3E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02975 c0e95d5210623af0530050b7724fc6c0 205 Hamap MF_02113_A Proteasome subunit beta [prcB]. 1 197 34.862 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 N186_02975 c0e95d5210623af0530050b7724fc6c0 205 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 6 188 2.0E-68 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 N186_02975 c0e95d5210623af0530050b7724fc6c0 205 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 9 56 - T 31-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02975 c0e95d5210623af0530050b7724fc6c0 205 Gene3D G3DSA:3.60.20.10 7 204 4.8E-61 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_02975 c0e95d5210623af0530050b7724fc6c0 205 SUPERFAMILY SSF56235 6 195 5.7E-60 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_02975 c0e95d5210623af0530050b7724fc6c0 205 Pfam PF00227 Proteasome subunit 6 184 2.1E-53 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_03775 b4960540b5b7681fc45167e73c758201 57 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 13 47 9.9E-7 T 31-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_03775 b4960540b5b7681fc45167e73c758201 57 SMART SM00659 11 57 6.1E-9 T 31-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_03775 b4960540b5b7681fc45167e73c758201 57 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 13 57 14.724 T 31-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_03775 b4960540b5b7681fc45167e73c758201 57 SUPERFAMILY SSF63393 12 56 1.26E-10 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 N186_03775 b4960540b5b7681fc45167e73c758201 57 Gene3D G3DSA:2.20.28.30 10 57 3.4E-17 T 31-10-2018 N186_00100 7c2b0523bd1230c074bc0349de127d65 374 SUPERFAMILY SSF53448 25 110 5.98E-6 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_00100 7c2b0523bd1230c074bc0349de127d65 374 Pfam PF01066 CDP-alcohol phosphatidyltransferase 193 249 1.7E-7 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 N186_00100 7c2b0523bd1230c074bc0349de127d65 374 Gene3D G3DSA:1.20.120.1760 166 367 1.7E-20 T 31-10-2018 N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 Gene3D G3DSA:3.50.50.60 40 342 2.3E-50 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 38 60 1.4E-9 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 224 240 1.4E-9 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 310 328 1.4E-9 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 Gene3D G3DSA:3.50.50.60 135 280 2.3E-50 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 3.9E-18 T 31-10-2018 N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 288 3.9E-18 T 31-10-2018 N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 39 58 3.9E-18 T 31-10-2018 N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 3.9E-18 T 31-10-2018 N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 37 334 8.6E-30 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 N186_00020 c355186e79d621e3d4fdb6fcdb62bef0 350 SUPERFAMILY SSF51971 36 280 2.88E-51 T 31-10-2018 N186_09605 623f9b6dd8af9b9b5840d86600ff4711 272 Pfam PF01925 Sulfite exporter TauE/SafE 9 266 5.2E-45 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 N186_06790 6d2618c6d72b36fd41e6b8fd27a398e7 360 Pfam PF00149 Calcineurin-like phosphoesterase 25 289 2.9E-11 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 N186_06790 6d2618c6d72b36fd41e6b8fd27a398e7 360 SUPERFAMILY SSF56300 25 311 1.73E-27 T 31-10-2018 N186_06790 6d2618c6d72b36fd41e6b8fd27a398e7 360 Gene3D G3DSA:3.60.21.10 23 162 4.0E-11 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_06790 6d2618c6d72b36fd41e6b8fd27a398e7 360 Gene3D G3DSA:3.60.21.10 250 342 1.3E-7 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_09710 1a6e1e666dd1a8713eb4c5c6f8337541 482 SMART SM00881 8 103 6.2E-35 T 31-10-2018 IPR003781 CoA-binding GO:0048037 N186_09710 1a6e1e666dd1a8713eb4c5c6f8337541 482 SUPERFAMILY SSF52210 297 453 2.88E-38 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_09710 1a6e1e666dd1a8713eb4c5c6f8337541 482 SUPERFAMILY SSF52210 133 289 3.4E-40 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_09710 1a6e1e666dd1a8713eb4c5c6f8337541 482 Gene3D G3DSA:3.40.50.720 3 130 1.1E-46 T 31-10-2018 N186_09710 1a6e1e666dd1a8713eb4c5c6f8337541 482 Gene3D G3DSA:3.40.50.261 131 292 9.3E-56 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_09710 1a6e1e666dd1a8713eb4c5c6f8337541 482 SUPERFAMILY SSF51735 5 138 6.28E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_09710 1a6e1e666dd1a8713eb4c5c6f8337541 482 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 152 289 6.8E-48 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain N186_09710 1a6e1e666dd1a8713eb4c5c6f8337541 482 Gene3D G3DSA:3.40.50.261 295 462 9.1E-53 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_09710 1a6e1e666dd1a8713eb4c5c6f8337541 482 Pfam PF13380 CoA binding domain 13 130 1.0E-25 T 31-10-2018 IPR003781 CoA-binding GO:0048037 N186_01835 e8595c19b4246ab80e8b5ae698800572 368 PIRSF PIRSF015647 1 368 1.1E-182 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 N186_01835 e8595c19b4246ab80e8b5ae698800572 368 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 4 362 4.0E-152 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 N186_01835 e8595c19b4246ab80e8b5ae698800572 368 SUPERFAMILY SSF111249 2 363 1.7E-170 T 31-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 N186_01835 e8595c19b4246ab80e8b5ae698800572 368 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 363 60.406 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 N186_01835 e8595c19b4246ab80e8b5ae698800572 368 Pfam PF01950 Fructose-1,6-bisphosphatase 2 362 1.1E-185 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 N186_06015 b352b8b6d100a2685387b4b97671534d 408 PIRSF PIRSF000484 72 407 5.6E-54 T 31-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 N186_06015 b352b8b6d100a2685387b4b97671534d 408 PIRSF PIRSF000484 13 81 0.13 T 31-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 N186_06015 b352b8b6d100a2685387b4b97671534d 408 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 56 124 2.3E-5 T 31-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 N186_06015 b352b8b6d100a2685387b4b97671534d 408 SUPERFAMILY SSF54675 7 126 6.04E-32 T 31-10-2018 N186_06015 b352b8b6d100a2685387b4b97671534d 408 Gene3D G3DSA:3.90.1170.20 2 117 4.6E-35 T 31-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 N186_06015 b352b8b6d100a2685387b4b97671534d 408 SUPERFAMILY SSF51690 123 405 2.94E-70 T 31-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 N186_06015 b352b8b6d100a2685387b4b97671534d 408 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 126 319 1.0E-23 T 31-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 N186_06015 b352b8b6d100a2685387b4b97671534d 408 Gene3D G3DSA:3.20.20.70 118 313 7.4E-62 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 154 291 5.4E-52 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain N186_04370 177bc3460a02d059f76f141f39bca5d1 709 SUPERFAMILY SSF52210 135 293 9.29E-41 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 Gene3D G3DSA:3.40.50.720 4 132 1.8E-45 T 31-10-2018 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 SMART SM00881 9 105 1.8E-35 T 31-10-2018 IPR003781 CoA-binding GO:0048037 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 SUPERFAMILY SSF51735 8 137 4.53E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_04370 177bc3460a02d059f76f141f39bca5d1 709 SUPERFAMILY SSF52210 297 451 3.79E-35 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 Gene3D G3DSA:3.30.1490.20 506 583 1.4E-79 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 Gene3D G3DSA:3.30.470.20 488 699 1.4E-79 T 31-10-2018 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 Pfam PF13549 ATP-grasp domain 479 701 5.1E-79 T 31-10-2018 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 Gene3D G3DSA:3.40.50.261 133 294 1.8E-57 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 SUPERFAMILY SSF56059 492 702 1.74E-41 T 31-10-2018 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 Gene3D G3DSA:3.40.50.261 295 464 6.0E-53 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_04370 177bc3460a02d059f76f141f39bca5d1 709 Pfam PF13380 CoA binding domain 14 136 1.7E-23 T 31-10-2018 IPR003781 CoA-binding GO:0048037 N186_08280 dd8f6543572b81944ef6c8f81dc47215 533 SUPERFAMILY SSF52540 270 494 6.81E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08280 dd8f6543572b81944ef6c8f81dc47215 533 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_08280 dd8f6543572b81944ef6c8f81dc47215 533 Pfam PF00005 ABC transporter 19 169 1.8E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_08280 dd8f6543572b81944ef6c8f81dc47215 533 Pfam PF00005 ABC transporter 287 433 4.1E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_08280 dd8f6543572b81944ef6c8f81dc47215 533 SMART SM00382 296 480 2.2E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_08280 dd8f6543572b81944ef6c8f81dc47215 533 SMART SM00382 28 220 1.6E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_08280 dd8f6543572b81944ef6c8f81dc47215 533 Gene3D G3DSA:3.40.50.300 268 533 3.0E-66 T 31-10-2018 N186_08280 dd8f6543572b81944ef6c8f81dc47215 533 SUPERFAMILY SSF52540 1 226 6.75E-54 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08280 dd8f6543572b81944ef6c8f81dc47215 533 Gene3D G3DSA:3.40.50.300 1 253 4.1E-61 T 31-10-2018 N186_01100 3a1ace871623a6372b1225492efaa006 154 Pfam PF05942 Archaeal PaREP1/PaREP8 family 31 143 4.3E-27 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_01100 3a1ace871623a6372b1225492efaa006 154 Gene3D G3DSA:1.20.120.330 28 153 7.1E-36 T 31-10-2018 N186_04740 6adb8690939a970094c2226ed26b1b55 364 SUPERFAMILY SSF52540 59 296 8.27E-21 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04740 6adb8690939a970094c2226ed26b1b55 364 Gene3D G3DSA:3.10.20.30 284 364 8.5E-24 T 31-10-2018 IPR012675 Beta-grasp domain superfamily N186_04740 6adb8690939a970094c2226ed26b1b55 364 Pfam PF02824 TGS domain 291 363 1.3E-16 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 N186_04740 6adb8690939a970094c2226ed26b1b55 364 Pfam PF01926 50S ribosome-binding GTPase 68 157 3.9E-8 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_04740 6adb8690939a970094c2226ed26b1b55 364 Pfam PF16897 C-terminal region of MMR_HSR1 domain 179 290 1.6E-15 T 31-10-2018 IPR031662 GTP binding protein, second domain N186_04740 6adb8690939a970094c2226ed26b1b55 364 SUPERFAMILY SSF81271 285 363 5.76E-19 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 N186_04550 a5fea021f4eae44fd8a7cc538c2d2ab5 103 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 9 99 24.256 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04550 a5fea021f4eae44fd8a7cc538c2d2ab5 103 Gene3D G3DSA:3.10.450.80 8 103 1.3E-28 T 31-10-2018 N186_04550 a5fea021f4eae44fd8a7cc538c2d2ab5 103 Pfam PF00935 Ribosomal protein L44 24 98 7.6E-28 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04550 a5fea021f4eae44fd8a7cc538c2d2ab5 103 ProSitePatterns PS01172 Ribosomal protein L44e signature. 68 79 - T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04550 a5fea021f4eae44fd8a7cc538c2d2ab5 103 SUPERFAMILY SSF57829 9 99 3.66E-28 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 N186_04550 a5fea021f4eae44fd8a7cc538c2d2ab5 103 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 17 100 4.0E-30 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03130 e74e22a8974fb343934c069c6ccb6c0e 106 SUPERFAMILY SSF50249 19 100 4.57E-28 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_03130 e74e22a8974fb343934c069c6ccb6c0e 106 SMART SM00652 16 99 7.1E-36 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 N186_03130 e74e22a8974fb343934c069c6ccb6c0e 106 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 5 99 26.183 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 N186_03130 e74e22a8974fb343934c069c6ccb6c0e 106 Pfam PF01176 Translation initiation factor 1A / IF-1 24 83 5.1E-22 T 31-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 N186_03130 e74e22a8974fb343934c069c6ccb6c0e 106 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 30 52 - T 31-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 N186_03130 e74e22a8974fb343934c069c6ccb6c0e 106 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 42 85 1.0E-13 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 N186_03130 e74e22a8974fb343934c069c6ccb6c0e 106 Gene3D G3DSA:2.40.50.140 1 104 7.4E-33 T 31-10-2018 N186_03130 e74e22a8974fb343934c069c6ccb6c0e 106 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 13 100 5.1E-31 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 N186_04355 6f4b738acf55bf4ce0acb5efb9e38458 239 Gene3D G3DSA:3.40.50.300 4 239 4.0E-61 T 31-10-2018 N186_04355 6f4b738acf55bf4ce0acb5efb9e38458 239 SMART SM00382 31 224 5.2E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04355 6f4b738acf55bf4ce0acb5efb9e38458 239 Pfam PF00005 ABC transporter 23 167 2.6E-33 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_04355 6f4b738acf55bf4ce0acb5efb9e38458 239 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_04355 6f4b738acf55bf4ce0acb5efb9e38458 239 SUPERFAMILY SSF52540 6 236 6.39E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06905 eaa90a1719ecec6b047e23aa6dff505f 592 Gene3D G3DSA:3.40.50.1820 27 200 1.2E-30 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_06905 eaa90a1719ecec6b047e23aa6dff505f 592 Pfam PF12146 Serine aminopeptidase, S33 63 180 6.4E-9 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 N186_06905 eaa90a1719ecec6b047e23aa6dff505f 592 SUPERFAMILY SSF53474 15 205 3.32E-31 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_07030 1eba4dec80c00d20a02ed861f0a33426 234 SUPERFAMILY SSF51695 5 229 2.09E-64 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 N186_07030 1eba4dec80c00d20a02ed861f0a33426 234 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 11 222 8.6E-38 T 31-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 N186_07030 1eba4dec80c00d20a02ed861f0a33426 234 Gene3D G3DSA:3.20.20.190 2 233 2.1E-65 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 N186_03220 2ec5e54d207f7d7a37e2b261f1a83a50 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 239 1.4E-73 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 N186_03220 2ec5e54d207f7d7a37e2b261f1a83a50 394 Gene3D G3DSA:3.40.50.970 2 251 2.3E-96 T 31-10-2018 N186_03220 2ec5e54d207f7d7a37e2b261f1a83a50 394 Gene3D G3DSA:3.40.50.920 253 393 3.5E-40 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 N186_03220 2ec5e54d207f7d7a37e2b261f1a83a50 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 366 5.7E-27 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II N186_03220 2ec5e54d207f7d7a37e2b261f1a83a50 394 SUPERFAMILY SSF52518 3 251 1.01E-70 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold N186_03220 2ec5e54d207f7d7a37e2b261f1a83a50 394 SUPERFAMILY SSF52922 255 373 4.06E-32 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 N186_05850 f2115d6fbb5ebdedfce0e1727f90706c 107 Gene3D G3DSA:1.10.10.1410 1 58 8.1E-27 T 31-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05850 f2115d6fbb5ebdedfce0e1727f90706c 107 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 106 13.487 T 31-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05850 f2115d6fbb5ebdedfce0e1727f90706c 107 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 106 6.0E-40 T 31-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 N186_05850 f2115d6fbb5ebdedfce0e1727f90706c 107 Pfam PF00428 60s Acidic ribosomal protein 16 105 2.6E-20 T 31-10-2018 N186_05450 dae9626ebfd1f6a47872055256a27e91 545 Gene3D G3DSA:1.10.10.350 443 534 4.9E-17 T 31-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 N186_05450 dae9626ebfd1f6a47872055256a27e91 545 Pfam PF01921 tRNA synthetases class I (K) 2 363 3.9E-92 T 31-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 N186_05450 dae9626ebfd1f6a47872055256a27e91 545 Gene3D G3DSA:2.30.30.300 175 221 1.5E-69 T 31-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 N186_05450 dae9626ebfd1f6a47872055256a27e91 545 Gene3D G3DSA:1.10.10.770 329 440 2.9E-22 T 31-10-2018 N186_05450 dae9626ebfd1f6a47872055256a27e91 545 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 536 28.345 T 31-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 N186_05450 dae9626ebfd1f6a47872055256a27e91 545 SUPERFAMILY SSF48163 329 534 3.27E-28 T 31-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 N186_05450 dae9626ebfd1f6a47872055256a27e91 545 SUPERFAMILY SSF52374 3 326 5.28E-32 T 31-10-2018 N186_05450 dae9626ebfd1f6a47872055256a27e91 545 Gene3D G3DSA:3.40.50.620 4 276 1.5E-69 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_05450 dae9626ebfd1f6a47872055256a27e91 545 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 3 533 1.9E-91 T 31-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 N186_06475 7fcabde7d73d72c29e3799b4efb52a30 194 SMART SM00155 136 163 1.2E-4 T 31-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 N186_06475 7fcabde7d73d72c29e3799b4efb52a30 194 Gene3D G3DSA:3.30.870.10 24 192 1.5E-38 T 31-10-2018 N186_06475 7fcabde7d73d72c29e3799b4efb52a30 194 Pfam PF13091 PLD-like domain 64 189 2.6E-25 T 31-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 N186_06475 7fcabde7d73d72c29e3799b4efb52a30 194 SUPERFAMILY SSF56024 27 191 9.64E-32 T 31-10-2018 N186_06670 e99df4061d7b93cad40b01abe9848d4b 385 SUPERFAMILY SSF51556 52 344 1.36E-88 T 31-10-2018 IPR032466 Metal-dependent hydrolase N186_06670 e99df4061d7b93cad40b01abe9848d4b 385 SUPERFAMILY SSF51338 3 384 1.34E-13 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 N186_06670 e99df4061d7b93cad40b01abe9848d4b 385 Pfam PF01979 Amidohydrolase family 48 382 1.5E-20 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 N186_06670 e99df4061d7b93cad40b01abe9848d4b 385 Gene3D G3DSA:3.20.20.140 52 353 2.7E-123 T 31-10-2018 N186_06670 e99df4061d7b93cad40b01abe9848d4b 385 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 5 379 9.5E-90 T 31-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 N186_06670 e99df4061d7b93cad40b01abe9848d4b 385 Gene3D G3DSA:2.30.40.10 12 380 2.7E-123 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 N186_06670 e99df4061d7b93cad40b01abe9848d4b 385 PIRSF PIRSF038994 2 385 4.8E-118 T 31-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 N186_02130 7f1dd932b5a504b526ded7fe7110098b 132 Gene3D G3DSA:2.30.30.30 2 131 1.7E-43 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 N186_02130 7f1dd932b5a504b526ded7fe7110098b 132 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 7 122 2.1E-26 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02130 7f1dd932b5a504b526ded7fe7110098b 132 ProSitePatterns PS01108 Ribosomal protein L24 signature. 52 69 - T 31-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02130 7f1dd932b5a504b526ded7fe7110098b 132 Pfam PF00467 KOW motif 51 82 6.3E-8 T 31-10-2018 IPR005824 KOW N186_02130 7f1dd932b5a504b526ded7fe7110098b 132 SMART SM00739 48 75 7.8E-6 T 31-10-2018 IPR005824 KOW N186_02130 7f1dd932b5a504b526ded7fe7110098b 132 SUPERFAMILY SSF50104 7 119 1.68E-31 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily N186_02130 7f1dd932b5a504b526ded7fe7110098b 132 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 7 121 28.862 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02130 7f1dd932b5a504b526ded7fe7110098b 132 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 7 122 8.2E-42 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_00540 0d7c301213379f2050f5b2cfc961a58f 330 Gene3D G3DSA:3.40.190.10 55 285 7.3E-87 T 31-10-2018 N186_00540 0d7c301213379f2050f5b2cfc961a58f 330 Pfam PF12849 PBP superfamily domain 50 243 9.5E-20 T 31-10-2018 IPR024370 PBP domain N186_00540 0d7c301213379f2050f5b2cfc961a58f 330 Gene3D G3DSA:3.40.190.10 131 248 7.3E-87 T 31-10-2018 N186_00540 0d7c301213379f2050f5b2cfc961a58f 330 SUPERFAMILY SSF53850 53 287 1.58E-26 T 31-10-2018 N186_08375 91150900ded63c04300e02c2e65781a0 303 SMART SM00382 28 208 8.3E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_08375 91150900ded63c04300e02c2e65781a0 303 SUPERFAMILY SSF52540 3 221 7.23E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08375 91150900ded63c04300e02c2e65781a0 303 Gene3D G3DSA:3.40.50.300 1 241 2.3E-54 T 31-10-2018 N186_08375 91150900ded63c04300e02c2e65781a0 303 Pfam PF00005 ABC transporter 19 158 1.7E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_01340 3e8647fc01d1381f89d157863ec43b20 605 Gene3D G3DSA:3.40.50.10490 443 590 1.0E-121 T 31-10-2018 N186_01340 3e8647fc01d1381f89d157863ec43b20 605 SUPERFAMILY SSF53697 250 605 3.43E-95 T 31-10-2018 N186_01340 3e8647fc01d1381f89d157863ec43b20 605 SUPERFAMILY SSF56235 2 233 5.06E-70 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_01340 3e8647fc01d1381f89d157863ec43b20 605 Gene3D G3DSA:3.40.50.10490 252 604 1.0E-121 T 31-10-2018 N186_01340 3e8647fc01d1381f89d157863ec43b20 605 Pfam PF13522 Glutamine amidotransferase domain 59 194 4.2E-23 T 31-10-2018 N186_01340 3e8647fc01d1381f89d157863ec43b20 605 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 605 5.0E-217 T 31-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 N186_01340 3e8647fc01d1381f89d157863ec43b20 605 Gene3D G3DSA:3.60.20.10 2 238 2.4E-73 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_01340 3e8647fc01d1381f89d157863ec43b20 605 Pfam PF01380 SIS domain 459 587 8.1E-19 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 N186_01340 3e8647fc01d1381f89d157863ec43b20 605 Pfam PF01380 SIS domain 286 410 5.7E-25 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 N186_01340 3e8647fc01d1381f89d157863ec43b20 605 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 605 37.182 T 31-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 N186_01525 c76763a7a6bbeb3537a85a02050958b4 305 Pfam PF01297 Zinc-uptake complex component A periplasmic 68 276 5.7E-16 T 31-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 N186_01525 c76763a7a6bbeb3537a85a02050958b4 305 SUPERFAMILY SSF53807 42 300 1.67E-29 T 31-10-2018 N186_01525 c76763a7a6bbeb3537a85a02050958b4 305 Gene3D G3DSA:3.40.50.1980 46 195 1.0E-16 T 31-10-2018 N186_04505 c8fe76f2033c8845d69af54a1dbad8d1 105 Pfam PF05129 Transcription elongation factor Elf1 like 2 78 6.4E-19 T 31-10-2018 IPR007808 Transcription elongation factor 1 N186_04505 c8fe76f2033c8845d69af54a1dbad8d1 105 Gene3D G3DSA:2.20.25.190 23 85 2.0E-7 T 31-10-2018 IPR038567 Transcription elongation factor 1 superfamily N186_04505 c8fe76f2033c8845d69af54a1dbad8d1 105 SUPERFAMILY SSF57783 1 82 8.08E-18 T 31-10-2018 N186_01965 a896ccf10a615373e829194971f97a54 171 Pfam PF00298 Ribosomal protein L11, RNA binding domain 75 142 9.9E-24 T 31-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 N186_01965 a896ccf10a615373e829194971f97a54 171 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 144 27.963 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 N186_01965 a896ccf10a615373e829194971f97a54 171 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 31-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01965 a896ccf10a615373e829194971f97a54 171 SMART SM00649 11 143 1.3E-60 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 N186_01965 a896ccf10a615373e829194971f97a54 171 Gene3D G3DSA:1.10.10.250 78 168 2.4E-33 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily N186_01965 a896ccf10a615373e829194971f97a54 171 Pfam PF03946 Ribosomal protein L11, N-terminal domain 14 65 1.9E-21 T 31-10-2018 IPR020784 Ribosomal protein L11, N-terminal N186_01965 a896ccf10a615373e829194971f97a54 171 SUPERFAMILY SSF46906 71 143 8.11E-23 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily N186_01965 a896ccf10a615373e829194971f97a54 171 Gene3D G3DSA:2.10.260.30 8 74 5.1E-26 T 31-10-2018 N186_01965 a896ccf10a615373e829194971f97a54 171 SUPERFAMILY SSF54747 8 87 2.75E-24 T 31-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily N186_06880 dd47b7c3117f54d61b33343126436eaa 289 Pfam PF03956 Lysine exporter LysO 101 284 2.2E-39 T 31-10-2018 IPR005642 Lysine exporter LysO N186_06880 dd47b7c3117f54d61b33343126436eaa 289 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 136 284 1.0E-22 T 31-10-2018 IPR005642 Lysine exporter LysO N186_02140 1fcbde4f284d1df6ab0d1d2515e145dc 347 Gene3D G3DSA:1.20.120.420 1 144 2.7E-48 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 N186_02140 1fcbde4f284d1df6ab0d1d2515e145dc 347 SUPERFAMILY SSF100950 3 340 2.18E-109 T 31-10-2018 IPR037171 NagB/RpiA transferase-like N186_02140 1fcbde4f284d1df6ab0d1d2515e145dc 347 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 6 333 7.7E-112 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 N186_02140 1fcbde4f284d1df6ab0d1d2515e145dc 347 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 34 334 1.5E-110 T 31-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 N186_02140 1fcbde4f284d1df6ab0d1d2515e145dc 347 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 4 344 34.975 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 N186_02140 1fcbde4f284d1df6ab0d1d2515e145dc 347 Gene3D G3DSA:3.40.50.10470 146 347 5.0E-61 T 31-10-2018 N186_02140 1fcbde4f284d1df6ab0d1d2515e145dc 347 Pfam PF01008 Initiation factor 2 subunit family 46 334 8.5E-79 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 N186_02610 ccece1b727bea5fcf457ab0815057428 487 Pfam PF00581 Rhodanese-like domain 401 479 2.4E-14 T 31-10-2018 IPR001763 Rhodanese-like domain N186_02610 ccece1b727bea5fcf457ab0815057428 487 Pfam PF02926 THUMP domain 34 160 4.3E-21 T 31-10-2018 IPR004114 THUMP domain GO:0003723 N186_02610 ccece1b727bea5fcf457ab0815057428 487 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 9 366 1.3E-97 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 N186_02610 ccece1b727bea5fcf457ab0815057428 487 Gene3D G3DSA:3.40.50.620 173 379 8.8E-56 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_02610 ccece1b727bea5fcf457ab0815057428 487 SMART SM00450 390 484 1.4E-18 T 31-10-2018 IPR001763 Rhodanese-like domain N186_02610 ccece1b727bea5fcf457ab0815057428 487 SUPERFAMILY SSF52821 399 481 1.57E-21 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily N186_02610 ccece1b727bea5fcf457ab0815057428 487 SUPERFAMILY SSF52402 173 331 9.26E-41 T 31-10-2018 N186_02610 ccece1b727bea5fcf457ab0815057428 487 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 487 146.342 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 N186_02610 ccece1b727bea5fcf457ab0815057428 487 Gene3D G3DSA:3.40.250.10 383 483 8.8E-21 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily N186_02610 ccece1b727bea5fcf457ab0815057428 487 SMART SM00981 75 163 3.5E-24 T 31-10-2018 IPR004114 THUMP domain GO:0003723 N186_02610 ccece1b727bea5fcf457ab0815057428 487 Gene3D G3DSA:3.30.2130.30 2 172 9.3E-43 T 31-10-2018 N186_02610 ccece1b727bea5fcf457ab0815057428 487 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 173 365 8.3E-60 T 31-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 N186_02610 ccece1b727bea5fcf457ab0815057428 487 SUPERFAMILY SSF143437 7 171 6.28E-44 T 31-10-2018 N186_03415 36d02faffe18f0e7bc8b82ff5d59c9a8 141 Pfam PF00238 Ribosomal protein L14p/L23e 23 140 5.6E-35 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 N186_03415 36d02faffe18f0e7bc8b82ff5d59c9a8 141 SMART SM01374 20 141 4.0E-57 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 N186_03415 36d02faffe18f0e7bc8b82ff5d59c9a8 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 14 141 4.5E-63 T 31-10-2018 IPR019971 Ribosomal protein L14P, archaeal N186_03415 36d02faffe18f0e7bc8b82ff5d59c9a8 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 20.405 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 N186_03415 36d02faffe18f0e7bc8b82ff5d59c9a8 141 SUPERFAMILY SSF50193 14 141 9.16E-42 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 N186_03415 36d02faffe18f0e7bc8b82ff5d59c9a8 141 Gene3D G3DSA:2.40.150.20 2 141 1.9E-47 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 N186_03415 36d02faffe18f0e7bc8b82ff5d59c9a8 141 ProSitePatterns PS00049 Ribosomal protein L14 signature. 80 106 - T 31-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01785 abb6ae5565ca855c827d5b2b1607f50a 327 Pfam PF01841 Transglutaminase-like superfamily 152 276 1.1E-20 T 31-10-2018 IPR002931 Transglutaminase-like N186_01785 abb6ae5565ca855c827d5b2b1607f50a 327 Gene3D G3DSA:3.10.620.30 105 292 1.1E-14 T 31-10-2018 N186_01785 abb6ae5565ca855c827d5b2b1607f50a 327 SMART SM00460 197 278 2.5E-7 T 31-10-2018 IPR002931 Transglutaminase-like N186_01785 abb6ae5565ca855c827d5b2b1607f50a 327 SUPERFAMILY SSF54001 147 287 5.05E-17 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily N186_03655 709c29e8e33e44e9c56e0a6d2dc04230 327 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 5 238 5.4E-28 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR N186_03655 709c29e8e33e44e9c56e0a6d2dc04230 327 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 251 4.0E-62 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR N186_02815 5b5694ed7df0de27214017f7197775ee 101 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 8 90 23.2 T 31-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type N186_02815 5b5694ed7df0de27214017f7197775ee 101 SUPERFAMILY SSF69695 7 97 1.57E-20 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 N186_02815 5b5694ed7df0de27214017f7197775ee 101 Gene3D G3DSA:3.30.56.30 5 101 1.3E-26 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 N186_02815 5b5694ed7df0de27214017f7197775ee 101 Pfam PF01922 SRP19 protein 8 90 1.5E-16 T 31-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 N186_03525 ea74a38ecbda06b47569f86b7a56b366 243 Pfam PF01163 RIO1 family 48 224 7.1E-53 T 31-10-2018 N186_03525 ea74a38ecbda06b47569f86b7a56b366 243 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 171 182 - T 31-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 N186_03525 ea74a38ecbda06b47569f86b7a56b366 243 Gene3D G3DSA:3.30.200.20 33 134 8.1E-11 T 31-10-2018 N186_03525 ea74a38ecbda06b47569f86b7a56b366 243 SMART SM00090 5 240 5.5E-77 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 N186_03525 ea74a38ecbda06b47569f86b7a56b366 243 SUPERFAMILY SSF56112 36 223 1.35E-24 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily N186_03525 ea74a38ecbda06b47569f86b7a56b366 243 Gene3D G3DSA:1.10.510.10 140 241 8.5E-25 T 31-10-2018 N186_09535 58d51b930a202359f4904279e9393a03 346 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 25 343 3.6E-89 T 31-10-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 N186_09535 58d51b930a202359f4904279e9393a03 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 44 147 3.0E-26 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 N186_09535 58d51b930a202359f4904279e9393a03 346 SUPERFAMILY SSF51735 155 313 3.29E-24 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_09535 58d51b930a202359f4904279e9393a03 346 SUPERFAMILY SSF50129 28 173 5.17E-40 T 31-10-2018 IPR011032 GroES-like superfamily N186_09535 58d51b930a202359f4904279e9393a03 346 Gene3D G3DSA:3.40.50.720 162 294 4.8E-80 T 31-10-2018 N186_09535 58d51b930a202359f4904279e9393a03 346 Gene3D G3DSA:3.90.180.10 30 338 4.8E-80 T 31-10-2018 N186_09535 58d51b930a202359f4904279e9393a03 346 Pfam PF00107 Zinc-binding dehydrogenase 192 307 3.2E-9 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 N186_01170 1938690f13b0144ccd60a7437ddd466d 120 Pfam PF03259 Roadblock/LC7 domain 8 96 1.9E-11 T 31-10-2018 IPR004942 Roadblock/LAMTOR2 domain N186_01170 1938690f13b0144ccd60a7437ddd466d 120 Gene3D G3DSA:3.30.450.30 4 119 7.3E-19 T 31-10-2018 N186_01170 1938690f13b0144ccd60a7437ddd466d 120 SMART SM00960 6 96 2.2E-16 T 31-10-2018 IPR004942 Roadblock/LAMTOR2 domain N186_01170 1938690f13b0144ccd60a7437ddd466d 120 SUPERFAMILY SSF103196 3 117 2.09E-15 T 31-10-2018 N186_06850 b90cc3a690428827642e33c7cc573363 136 ProSitePatterns PS00194 Thioredoxin family active site. 51 69 - T 31-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 N186_06850 b90cc3a690428827642e33c7cc573363 136 SUPERFAMILY SSF52833 5 135 1.11E-30 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_06850 b90cc3a690428827642e33c7cc573363 136 TIGRFAM TIGR01068 thioredoxin: thioredoxin 39 129 1.9E-30 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 N186_06850 b90cc3a690428827642e33c7cc573363 136 PIRSF PIRSF000077 33 135 1.4E-30 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 N186_06850 b90cc3a690428827642e33c7cc573363 136 Gene3D G3DSA:3.40.30.10 20 135 1.9E-29 T 31-10-2018 N186_06850 b90cc3a690428827642e33c7cc573363 136 PRINTS PR00421 Thioredoxin family signature 98 109 7.0E-6 T 31-10-2018 N186_06850 b90cc3a690428827642e33c7cc573363 136 PRINTS PR00421 Thioredoxin family signature 58 67 7.0E-6 T 31-10-2018 N186_06850 b90cc3a690428827642e33c7cc573363 136 PRINTS PR00421 Thioredoxin family signature 50 58 7.0E-6 T 31-10-2018 N186_06850 b90cc3a690428827642e33c7cc573363 136 Pfam PF00085 Thioredoxin 39 120 9.4E-24 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 N186_01945 ee2d31ee0d9853e53e9749bd5a7a64cd 117 Gene3D G3DSA:1.10.8.10 74 113 6.2E-18 T 31-10-2018 N186_01945 ee2d31ee0d9853e53e9749bd5a7a64cd 117 SUPERFAMILY SSF46934 74 116 1.0E-7 T 31-10-2018 IPR009060 UBA-like superfamily GO:0005515 N186_01945 ee2d31ee0d9853e53e9749bd5a7a64cd 117 SMART SM01407 5 65 1.3E-12 T 31-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain N186_01945 ee2d31ee0d9853e53e9749bd5a7a64cd 117 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 6 113 18.61 T 31-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 N186_01945 ee2d31ee0d9853e53e9749bd5a7a64cd 117 Pfam PF01849 NAC domain 7 64 4.7E-10 T 31-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain N186_01945 ee2d31ee0d9853e53e9749bd5a7a64cd 117 Gene3D G3DSA:2.20.70.30 10 71 2.2E-13 T 31-10-2018 IPR038187 NAC A/B domain superfamily N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 Gene3D G3DSA:3.90.740.10 219 461 2.0E-274 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 685 7.6E-60 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 24 974 1.0E-300 T 31-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 Gene3D G3DSA:3.30.2320.20 835 974 4.5E-16 T 31-10-2018 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 Gene3D G3DSA:1.10.10.720 865 922 4.5E-16 T 31-10-2018 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 SUPERFAMILY SSF52374 22 703 1.05E-102 T 31-10-2018 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 SUPERFAMILY SSF50677 223 453 3.23E-32 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 Pfam PF08264 Anticodon-binding domain of tRNA 730 862 1.7E-20 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 22 974 15.979 T 31-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 Gene3D G3DSA:1.10.730.10 698 810 1.2E-15 T 31-10-2018 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 Gene3D G3DSA:3.40.50.620 25 688 2.0E-274 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04300 835ba2812f888c20ae5ef0a77f65897c 975 SUPERFAMILY SSF47323 708 889 7.48E-27 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_05345 e5d2497d964aa353d743de88c807d347 389 Pfam PF00108 Thiolase, N-terminal domain 19 223 1.5E-23 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 N186_05345 e5d2497d964aa353d743de88c807d347 389 Pfam PF02803 Thiolase, C-terminal domain 262 370 3.6E-11 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 N186_05345 e5d2497d964aa353d743de88c807d347 389 SUPERFAMILY SSF53901 250 376 4.02E-29 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_05345 e5d2497d964aa353d743de88c807d347 389 Gene3D G3DSA:3.40.47.10 3 387 1.2E-115 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_05345 e5d2497d964aa353d743de88c807d347 389 PIRSF PIRSF000429 1 385 3.2E-57 T 31-10-2018 IPR002155 Thiolase GO:0016747 N186_05345 e5d2497d964aa353d743de88c807d347 389 SUPERFAMILY SSF53901 4 229 3.64E-45 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_07460 eae13ec613dc6f0ad40b4e83bec28587 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 240 7.6E-13 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_07460 eae13ec613dc6f0ad40b4e83bec28587 252 SUPERFAMILY SSF161098 1 252 4.71E-58 T 31-10-2018 IPR035906 MetI-like superfamily N186_07460 eae13ec613dc6f0ad40b4e83bec28587 252 Gene3D G3DSA:1.10.3720.10 1 243 6.2E-55 T 31-10-2018 IPR035906 MetI-like superfamily N186_08720 6968fd5fe99b9ed87eb1a6bafa141280 87 Gene3D G3DSA:2.10.260.10 2 44 1.4E-9 T 31-10-2018 N186_08720 6968fd5fe99b9ed87eb1a6bafa141280 87 SUPERFAMILY SSF89447 5 46 7.33E-10 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_08720 6968fd5fe99b9ed87eb1a6bafa141280 87 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 44 5.0E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08720 6968fd5fe99b9ed87eb1a6bafa141280 87 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 46 2.9E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08720 6968fd5fe99b9ed87eb1a6bafa141280 87 SMART SM00966 6 51 7.2E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_03055 b86259d3371deb596298bb7141081951 159 Gene3D G3DSA:3.30.70.940 11 96 7.5E-25 T 31-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 N186_03055 b86259d3371deb596298bb7141081951 159 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 11 90 1.6E-19 T 31-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 N186_03055 b86259d3371deb596298bb7141081951 159 Gene3D G3DSA:2.30.30.30 97 159 1.3E-23 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 N186_03055 b86259d3371deb596298bb7141081951 159 Pfam PF00467 KOW motif 101 132 9.7E-8 T 31-10-2018 IPR005824 KOW N186_03055 b86259d3371deb596298bb7141081951 159 SMART SM00739 98 125 3.0E-5 T 31-10-2018 IPR005824 KOW N186_03055 b86259d3371deb596298bb7141081951 159 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 11 154 36.972 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 N186_03055 b86259d3371deb596298bb7141081951 159 SUPERFAMILY SSF50104 64 153 9.89E-17 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily N186_03055 b86259d3371deb596298bb7141081951 159 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 13 156 1.4E-42 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 N186_03055 b86259d3371deb596298bb7141081951 159 SMART SM00738 9 93 5.7E-12 T 31-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 N186_04250 65691a42410520df8248eabb125089d9 647 PRINTS PR01038 Arginyl-tRNA synthetase signature 131 146 2.8E-12 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 N186_04250 65691a42410520df8248eabb125089d9 647 PRINTS PR01038 Arginyl-tRNA synthetase signature 170 183 2.8E-12 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 N186_04250 65691a42410520df8248eabb125089d9 647 PRINTS PR01038 Arginyl-tRNA synthetase signature 146 162 2.8E-12 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 N186_04250 65691a42410520df8248eabb125089d9 647 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 43 647 1.9E-127 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 N186_04250 65691a42410520df8248eabb125089d9 647 SUPERFAMILY SSF47323 525 647 2.75E-31 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04250 65691a42410520df8248eabb125089d9 647 Gene3D G3DSA:3.30.1360.70 14 122 9.8E-8 T 31-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 N186_04250 65691a42410520df8248eabb125089d9 647 Gene3D G3DSA:1.10.730.10 530 647 4.6E-31 T 31-10-2018 N186_04250 65691a42410520df8248eabb125089d9 647 Pfam PF05746 DALR anticodon binding domain 530 647 4.4E-32 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 N186_04250 65691a42410520df8248eabb125089d9 647 Hamap MF_00123 Arginine--tRNA ligase [argS]. 22 647 24.77 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 N186_04250 65691a42410520df8248eabb125089d9 647 SMART SM00836 530 647 9.7E-40 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 N186_04250 65691a42410520df8248eabb125089d9 647 Pfam PF00750 tRNA synthetases class I (R) 123 516 5.2E-31 T 31-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 N186_04250 65691a42410520df8248eabb125089d9 647 SUPERFAMILY SSF52374 128 523 4.69E-74 T 31-10-2018 N186_04250 65691a42410520df8248eabb125089d9 647 SUPERFAMILY SSF55190 13 122 6.02E-7 T 31-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 PIRSF PIRSF002158 1 248 1.3E-63 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 239 39.866 T 31-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 SUPERFAMILY SSF50104 96 238 3.85E-44 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 SMART SM01383 11 87 5.0E-26 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 96 223 2.6E-38 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 SUPERFAMILY SSF50249 2 93 4.86E-22 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 SMART SM01382 93 224 2.7E-55 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 86 4.3E-14 T 31-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 Gene3D G3DSA:2.30.30.30 87 164 9.6E-28 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 Gene3D G3DSA:2.40.50.140 1 83 5.5E-25 T 31-10-2018 N186_01985 59d46b70c1f90ee0ae7e307bcd3e1c80 248 Gene3D G3DSA:4.10.950.10 165 242 3.7E-25 T 31-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 Gene3D G3DSA:3.40.980.10 178 311 8.7E-60 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 Pfam PF03454 MoeA C-terminal region (domain IV) 324 394 3.1E-15 T 31-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 Gene3D G3DSA:2.40.340.10 322 397 3.3E-20 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 Pfam PF00994 Probable molybdopterin binding domain 183 310 9.2E-15 T 31-10-2018 IPR001453 MoaB/Mog domain N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 SUPERFAMILY SSF63867 321 396 2.62E-17 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 SUPERFAMILY SSF63882 5 177 6.67E-37 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 SUPERFAMILY SSF53218 181 312 1.96E-20 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 Gene3D G3DSA:2.170.190.11 47 144 8.7E-60 T 31-10-2018 N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 Pfam PF03453 MoeA N-terminal region (domain I and II) 19 166 3.2E-30 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 SMART SM00852 182 312 2.1E-13 T 31-10-2018 IPR001453 MoaB/Mog domain N186_05195 b0dd6073e793ad91c1657a664e4b2042 406 Gene3D G3DSA:3.90.105.10 25 177 8.7E-60 T 31-10-2018 N186_06780 b50142af356cdea338994f0bf24ba156 375 PIRSF PIRSF000530 1 368 1.4E-67 T 31-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 N186_06780 b50142af356cdea338994f0bf24ba156 375 SUPERFAMILY SSF54211 2 171 1.82E-43 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_06780 b50142af356cdea338994f0bf24ba156 375 Pfam PF00288 GHMP kinases N terminal domain 100 167 1.4E-15 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 N186_06780 b50142af356cdea338994f0bf24ba156 375 Gene3D G3DSA:3.30.70.890 183 355 1.2E-70 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily N186_06780 b50142af356cdea338994f0bf24ba156 375 SUPERFAMILY SSF55060 187 369 1.08E-24 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily N186_06780 b50142af356cdea338994f0bf24ba156 375 PRINTS PR00959 Mevalonate kinase family signature 147 166 1.3E-30 T 31-10-2018 N186_06780 b50142af356cdea338994f0bf24ba156 375 PRINTS PR00959 Mevalonate kinase family signature 327 344 1.3E-30 T 31-10-2018 N186_06780 b50142af356cdea338994f0bf24ba156 375 PRINTS PR00959 Mevalonate kinase family signature 6 30 1.3E-30 T 31-10-2018 N186_06780 b50142af356cdea338994f0bf24ba156 375 PRINTS PR00959 Mevalonate kinase family signature 104 126 1.3E-30 T 31-10-2018 N186_06780 b50142af356cdea338994f0bf24ba156 375 Pfam PF10509 Galactokinase galactose-binding signature 2 37 1.8E-9 T 31-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 N186_06780 b50142af356cdea338994f0bf24ba156 375 Pfam PF08544 GHMP kinases C terminal 288 357 1.3E-10 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain N186_06780 b50142af356cdea338994f0bf24ba156 375 Gene3D G3DSA:3.30.230.10 3 182 1.2E-70 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup N186_06780 b50142af356cdea338994f0bf24ba156 375 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 106 117 - T 31-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 N186_06780 b50142af356cdea338994f0bf24ba156 375 PRINTS PR00473 Galactokinase signature 75 86 1.7E-11 T 31-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 N186_06780 b50142af356cdea338994f0bf24ba156 375 PRINTS PR00473 Galactokinase signature 97 115 1.7E-11 T 31-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 N186_06780 b50142af356cdea338994f0bf24ba156 375 PRINTS PR00473 Galactokinase signature 8 26 1.7E-11 T 31-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 N186_02790 431b1c258acfcec6f4ffa7cf70f7c299 432 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 9 428 56.201 T 31-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 N186_02790 431b1c258acfcec6f4ffa7cf70f7c299 432 Gene3D G3DSA:3.30.70.2510 194 318 1.3E-37 T 31-10-2018 N186_02790 431b1c258acfcec6f4ffa7cf70f7c299 432 Pfam PF02926 THUMP domain 29 188 3.6E-7 T 31-10-2018 IPR004114 THUMP domain GO:0003723 N186_02790 431b1c258acfcec6f4ffa7cf70f7c299 432 Gene3D G3DSA:3.30.70.3190 319 427 2.0E-32 T 31-10-2018 N186_02790 431b1c258acfcec6f4ffa7cf70f7c299 432 SUPERFAMILY SSF55120 307 426 1.44E-12 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 N186_02790 431b1c258acfcec6f4ffa7cf70f7c299 432 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 11 428 5.9E-126 T 31-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 N186_02035 6e77112b456ff57cfa41a67d942bdfa6 1101 Pfam PF12469 CRISPR-associated protein 186 323 2.5E-25 T 31-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal N186_02035 6e77112b456ff57cfa41a67d942bdfa6 1101 Gene3D G3DSA:3.30.70.2230 788 952 1.1E-15 T 31-10-2018 N186_02035 6e77112b456ff57cfa41a67d942bdfa6 1101 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 185 921 2.9E-59 T 31-10-2018 IPR013407 CRISPR-associated protein Cmr2 N186_05140 146e941946a532b7faca3141a3c3f95f 608 SUPERFAMILY SSF52954 488 589 4.53E-28 T 31-10-2018 N186_05140 146e941946a532b7faca3141a3c3f95f 608 Gene3D G3DSA:3.30.930.10 202 475 8.1E-49 T 31-10-2018 N186_05140 146e941946a532b7faca3141a3c3f95f 608 SUPERFAMILY SSF55681 191 502 2.38E-41 T 31-10-2018 N186_05140 146e941946a532b7faca3141a3c3f95f 608 PRINTS PR01047 Threonyl-tRNA synthetase signature 281 309 8.0E-25 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 N186_05140 146e941946a532b7faca3141a3c3f95f 608 PRINTS PR01047 Threonyl-tRNA synthetase signature 489 501 8.0E-25 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 N186_05140 146e941946a532b7faca3141a3c3f95f 608 PRINTS PR01047 Threonyl-tRNA synthetase signature 454 467 8.0E-25 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 N186_05140 146e941946a532b7faca3141a3c3f95f 608 PRINTS PR01047 Threonyl-tRNA synthetase signature 411 439 8.0E-25 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 N186_05140 146e941946a532b7faca3141a3c3f95f 608 PRINTS PR01047 Threonyl-tRNA synthetase signature 314 337 8.0E-25 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 N186_05140 146e941946a532b7faca3141a3c3f95f 608 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 270 474 1.2E-19 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_05140 146e941946a532b7faca3141a3c3f95f 608 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 137 1.2E-49 T 31-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 N186_05140 146e941946a532b7faca3141a3c3f95f 608 Gene3D G3DSA:3.40.50.800 487 593 2.6E-29 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily N186_05140 146e941946a532b7faca3141a3c3f95f 608 Pfam PF03129 Anticodon binding domain 496 584 1.3E-21 T 31-10-2018 IPR004154 Anticodon-binding N186_05140 146e941946a532b7faca3141a3c3f95f 608 Gene3D G3DSA:3.50.80.10 1 137 1.2E-47 T 31-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily N186_05140 146e941946a532b7faca3141a3c3f95f 608 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 34 584 26.342 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 N186_05140 146e941946a532b7faca3141a3c3f95f 608 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 3 137 5.0E-28 T 31-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 N186_07770 22529a4e460eccf97cb96ad188ceab58 353 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 21 84 8.5E-14 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal N186_07770 22529a4e460eccf97cb96ad188ceab58 353 SUPERFAMILY SSF46785 11 103 5.3E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_07770 22529a4e460eccf97cb96ad188ceab58 353 Gene3D G3DSA:1.10.10.10 8 111 2.0E-15 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_07770 22529a4e460eccf97cb96ad188ceab58 353 Pfam PF11495 Archaeal transcriptional regulator TrmB 123 350 2.1E-44 T 31-10-2018 IPR021586 Transcription regulator TrmB, C-terminal N186_07770 22529a4e460eccf97cb96ad188ceab58 353 SUPERFAMILY SSF159071 261 349 2.09E-16 T 31-10-2018 N186_01750 6761ac5e65d1db8ad4c5f7c57b9fbc64 319 SUPERFAMILY SSF52540 2 284 1.73E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01750 6761ac5e65d1db8ad4c5f7c57b9fbc64 319 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 39 169 4.7E-66 T 31-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 N186_01750 6761ac5e65d1db8ad4c5f7c57b9fbc64 319 Gene3D G3DSA:3.40.50.300 20 186 6.6E-45 T 31-10-2018 N186_01750 6761ac5e65d1db8ad4c5f7c57b9fbc64 319 PIRSF PIRSF002849 1 314 4.7E-137 T 31-10-2018 N186_01750 6761ac5e65d1db8ad4c5f7c57b9fbc64 319 Gene3D G3DSA:1.10.8.300 201 309 4.6E-35 T 31-10-2018 N186_09095 82cc7ee9abfb06a4caaa31b8c361aa30 99 Pfam PF01909 Nucleotidyltransferase domain 13 80 2.2E-9 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_09095 82cc7ee9abfb06a4caaa31b8c361aa30 99 Gene3D G3DSA:3.30.460.10 13 99 5.4E-14 T 31-10-2018 N186_09095 82cc7ee9abfb06a4caaa31b8c361aa30 99 SUPERFAMILY SSF81301 28 96 1.54E-13 T 31-10-2018 N186_01905 79d897f95e7bde701e65aad53438b994 94 Pfam PF01918 Alba 9 69 4.1E-15 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 N186_01905 79d897f95e7bde701e65aad53438b994 94 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 4 92 21.355 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 N186_01905 79d897f95e7bde701e65aad53438b994 94 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 9 92 2.3E-28 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 N186_01905 79d897f95e7bde701e65aad53438b994 94 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 12 92 5.0E-21 T 31-10-2018 N186_01905 79d897f95e7bde701e65aad53438b994 94 Gene3D G3DSA:3.30.110.20 5 92 1.6E-29 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 N186_01905 79d897f95e7bde701e65aad53438b994 94 SUPERFAMILY SSF82704 4 92 3.79E-20 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 N186_01905 79d897f95e7bde701e65aad53438b994 94 PIRSF PIRSF028732 4 93 1.4E-30 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 N186_03205 0a37c9db1c22e71ab8835c86c817c2e8 348 SUPERFAMILY SSF52768 39 320 7.67E-83 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily N186_03205 0a37c9db1c22e71ab8835c86c817c2e8 348 Gene3D G3DSA:3.40.800.20 29 346 1.3E-84 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 N186_03205 0a37c9db1c22e71ab8835c86c817c2e8 348 PRINTS PR01270 Histone deacetylase superfamily signature 240 250 7.7E-19 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 N186_03205 0a37c9db1c22e71ab8835c86c817c2e8 348 PRINTS PR01270 Histone deacetylase superfamily signature 156 171 7.7E-19 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 N186_03205 0a37c9db1c22e71ab8835c86c817c2e8 348 PRINTS PR01270 Histone deacetylase superfamily signature 123 146 7.7E-19 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 N186_03205 0a37c9db1c22e71ab8835c86c817c2e8 348 Pfam PF00850 Histone deacetylase domain 47 306 3.6E-63 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 N186_02235 11c43fc64b1122fb35b3daf1c9f8a8cb 421 Gene3D G3DSA:3.40.50.300 10 168 6.7E-46 T 31-10-2018 N186_02235 11c43fc64b1122fb35b3daf1c9f8a8cb 421 Hamap MF_01508 Replication factor C large subunit [rfcL]. 10 420 33.322 T 31-10-2018 IPR023935 Replication factor C, large subunit N186_02235 11c43fc64b1122fb35b3daf1c9f8a8cb 421 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 157 3.3E-14 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 N186_02235 11c43fc64b1122fb35b3daf1c9f8a8cb 421 SUPERFAMILY SSF52540 10 230 2.01E-43 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02235 11c43fc64b1122fb35b3daf1c9f8a8cb 421 Pfam PF03215 Rad17 cell cycle checkpoint protein 164 221 9.8E-5 T 31-10-2018 N186_02235 11c43fc64b1122fb35b3daf1c9f8a8cb 421 Gene3D G3DSA:1.10.8.60 171 230 1.2E-15 T 31-10-2018 N186_02235 11c43fc64b1122fb35b3daf1c9f8a8cb 421 SMART SM00382 47 170 2.1E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_05110 470cdea0c4b529c8f1f11d584400921a 213 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 2 207 3.9E-62 T 31-10-2018 IPR023473 AMMECR1 N186_05110 470cdea0c4b529c8f1f11d584400921a 213 Gene3D G3DSA:3.30.1490.150 118 192 4.8E-74 T 31-10-2018 N186_05110 470cdea0c4b529c8f1f11d584400921a 213 SUPERFAMILY SSF143447 2 210 2.62E-66 T 31-10-2018 IPR036071 AMMECR1 domain superfamily N186_05110 470cdea0c4b529c8f1f11d584400921a 213 Gene3D G3DSA:3.30.700.20 4 204 4.8E-74 T 31-10-2018 IPR027485 AMMECR1, N-terminal N186_05110 470cdea0c4b529c8f1f11d584400921a 213 Pfam PF01871 AMMECR1 13 196 5.2E-50 T 31-10-2018 IPR002733 AMMECR1 domain N186_05110 470cdea0c4b529c8f1f11d584400921a 213 Hamap MF_00645 Protein . 5 194 38.129 T 31-10-2018 IPR023472 Uncharacterised protein family MJ0810 N186_05110 470cdea0c4b529c8f1f11d584400921a 213 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 196 2.2E-57 T 31-10-2018 IPR027623 AmmeMemoRadiSam system protein A N186_02590 51bdc04f77e29b467cc805c9d977d791 295 SMART SM01400 1 116 2.5E-27 T 31-10-2018 N186_02590 51bdc04f77e29b467cc805c9d977d791 295 Pfam PF00156 Phosphoribosyl transferase domain 156 253 1.9E-18 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 N186_02590 51bdc04f77e29b467cc805c9d977d791 295 SUPERFAMILY SSF53271 83 271 2.8E-40 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_02590 51bdc04f77e29b467cc805c9d977d791 295 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 116 6.5E-21 T 31-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 N186_02590 51bdc04f77e29b467cc805c9d977d791 295 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 2 290 2.1E-80 T 31-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 N186_02590 51bdc04f77e29b467cc805c9d977d791 295 Gene3D G3DSA:3.40.50.2020 1 152 1.2E-36 T 31-10-2018 N186_02590 51bdc04f77e29b467cc805c9d977d791 295 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 2 285 35.29 T 31-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 N186_02590 51bdc04f77e29b467cc805c9d977d791 295 Gene3D G3DSA:3.40.50.2020 153 280 5.9E-35 T 31-10-2018 N186_09220 7aed9c76cbfa322986e42ee72cd47746 943 SUPERFAMILY SSF52540 102 507 1.93E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09220 7aed9c76cbfa322986e42ee72cd47746 943 Gene3D G3DSA:3.40.50.300 312 501 5.7E-35 T 31-10-2018 N186_09220 7aed9c76cbfa322986e42ee72cd47746 943 Pfam PF13020 Domain of unknown function (DUF3883) 825 904 1.1E-16 T 31-10-2018 IPR024975 Domain of unknown function DUF3883 N186_09220 7aed9c76cbfa322986e42ee72cd47746 943 SMART SM00487 1 179 9.7E-11 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain N186_09220 7aed9c76cbfa322986e42ee72cd47746 943 Gene3D G3DSA:3.40.50.10810 1 250 9.7E-47 T 31-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily N186_09220 7aed9c76cbfa322986e42ee72cd47746 943 Pfam PF00176 SNF2 family N-terminal domain 10 237 3.5E-13 T 31-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 N186_09220 7aed9c76cbfa322986e42ee72cd47746 943 Pfam PF00271 Helicase conserved C-terminal domain 366 470 5.2E-16 T 31-10-2018 IPR001650 Helicase, C-terminal N186_09220 7aed9c76cbfa322986e42ee72cd47746 943 SUPERFAMILY SSF52540 5 177 2.66E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09220 7aed9c76cbfa322986e42ee72cd47746 943 SMART SM00490 389 470 1.5E-15 T 31-10-2018 IPR001650 Helicase, C-terminal N186_07385 6b38ef7f1ca1fe58869b4459dbe895d5 129 Gene3D G3DSA:3.30.70.1150 47 128 2.7E-20 T 31-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal N186_07385 6b38ef7f1ca1fe58869b4459dbe895d5 129 SUPERFAMILY SSF55021 50 128 1.46E-17 T 31-10-2018 N186_07385 6b38ef7f1ca1fe58869b4459dbe895d5 129 Pfam PF08753 NikR C terminal nickel binding domain 51 125 5.6E-20 T 31-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal N186_07385 6b38ef7f1ca1fe58869b4459dbe895d5 129 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 38 1.0E-5 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 N186_07385 6b38ef7f1ca1fe58869b4459dbe895d5 129 SUPERFAMILY SSF47598 1 38 4.0E-5 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 N186_02170 59b8b6179bac07ec6cc4493c5b8b5e0a 138 SUPERFAMILY SSF103196 7 117 2.62E-18 T 31-10-2018 N186_02170 59b8b6179bac07ec6cc4493c5b8b5e0a 138 SMART SM00960 9 99 7.5E-6 T 31-10-2018 IPR004942 Roadblock/LAMTOR2 domain N186_02170 59b8b6179bac07ec6cc4493c5b8b5e0a 138 Gene3D G3DSA:3.30.450.30 1 123 5.4E-10 T 31-10-2018 N186_05795 dff09531ac0d60b905ada1fbfa4c963b 477 Gene3D G3DSA:3.40.50.1100 29 438 1.7E-177 T 31-10-2018 N186_05795 dff09531ac0d60b905ada1fbfa4c963b 477 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 121 135 - T 31-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 N186_05795 dff09531ac0d60b905ada1fbfa4c963b 477 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 432 1.4E-41 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme N186_05795 dff09531ac0d60b905ada1fbfa4c963b 477 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 37 445 42.256 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 N186_05795 dff09531ac0d60b905ada1fbfa4c963b 477 PIRSF PIRSF001413 25 451 2.9E-133 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 N186_05795 dff09531ac0d60b905ada1fbfa4c963b 477 Gene3D G3DSA:3.40.50.1100 30 254 1.7E-177 T 31-10-2018 N186_05795 dff09531ac0d60b905ada1fbfa4c963b 477 PIRSF PIRSF500824 17 454 4.9E-216 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 N186_05795 dff09531ac0d60b905ada1fbfa4c963b 477 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 29 448 8.5E-210 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 N186_05795 dff09531ac0d60b905ada1fbfa4c963b 477 SUPERFAMILY SSF53686 43 444 1.96E-115 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme N186_07210 789488a82197f661133f8900c5cffb7d 220 SUPERFAMILY SSF52242 84 218 5.23E-48 T 31-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 N186_07210 789488a82197f661133f8900c5cffb7d 220 Pfam PF02310 B12 binding domain 98 209 7.1E-28 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 N186_07210 789488a82197f661133f8900c5cffb7d 220 SUPERFAMILY SSF47644 9 80 9.94E-14 T 31-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 N186_07210 789488a82197f661133f8900c5cffb7d 220 Pfam PF02607 B12 binding domain 10 81 3.7E-13 T 31-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 N186_07210 789488a82197f661133f8900c5cffb7d 220 Gene3D G3DSA:3.40.50.280 88 220 9.2E-52 T 31-10-2018 N186_07210 789488a82197f661133f8900c5cffb7d 220 SMART SM01018 7 91 6.0E-16 T 31-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 N186_07210 789488a82197f661133f8900c5cffb7d 220 Gene3D G3DSA:1.10.1240.10 6 87 9.2E-19 T 31-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 SUPERFAMILY SSF53738 5 173 1.73E-29 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 132 6.5E-24 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 368 437 1.4E-12 T 31-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 Gene3D G3DSA:3.40.120.10 4 143 7.6E-32 T 31-10-2018 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 151 248 3.5E-22 T 31-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 SUPERFAMILY SSF53738 257 352 1.41E-17 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 SUPERFAMILY SSF53738 149 250 7.06E-25 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 352 6.5E-16 T 31-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 Gene3D G3DSA:3.40.120.10 249 349 8.5E-52 T 31-10-2018 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 SUPERFAMILY SSF55957 354 443 9.81E-24 T 31-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 Gene3D G3DSA:3.30.310.50 359 446 5.9E-25 T 31-10-2018 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 Gene3D G3DSA:3.40.120.10 162 346 8.5E-52 T 31-10-2018 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 228 243 3.1E-13 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 166 185 3.1E-13 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05520 4b15d7050775c56fbb1250e5b2ec03c2 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 90 104 3.1E-13 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_09435 1f9d8bacdffa314d59ec5752025346ae 97 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 10 89 5.0E-7 T 31-10-2018 N186_09435 1f9d8bacdffa314d59ec5752025346ae 97 Gene3D G3DSA:3.30.110.20 5 90 1.1E-17 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 N186_09435 1f9d8bacdffa314d59ec5752025346ae 97 Pfam PF01918 Alba 7 67 1.8E-8 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 N186_09435 1f9d8bacdffa314d59ec5752025346ae 97 SUPERFAMILY SSF82704 9 89 3.14E-12 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 N186_03100 f8995fce880b7e2997bd0f9d37f67e3d 211 Gene3D G3DSA:3.30.1490.120 17 96 7.7E-26 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 N186_03100 f8995fce880b7e2997bd0f9d37f67e3d 211 SUPERFAMILY SSF50249 97 186 6.94E-16 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_03100 f8995fce880b7e2997bd0f9d37f67e3d 211 Gene3D G3DSA:2.40.50.140 98 199 2.7E-18 T 31-10-2018 N186_03100 f8995fce880b7e2997bd0f9d37f67e3d 211 SMART SM00316 96 184 7.6E-8 T 31-10-2018 IPR022967 RNA-binding domain, S1 N186_03100 f8995fce880b7e2997bd0f9d37f67e3d 211 Pfam PF00575 S1 RNA binding domain 98 179 3.3E-12 T 31-10-2018 IPR003029 S1 domain GO:0003676 N186_03100 f8995fce880b7e2997bd0f9d37f67e3d 211 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 24 93 1.0E-15 T 31-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 N186_03100 f8995fce880b7e2997bd0f9d37f67e3d 211 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 17 196 8.0E-49 T 31-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 N186_03100 f8995fce880b7e2997bd0f9d37f67e3d 211 SUPERFAMILY SSF88798 18 93 1.83E-20 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 16 125 9.2E-21 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 439 512 7.0E-21 T 31-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 268 429 1.3E-48 T 31-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 SUPERFAMILY SSF143243 9 168 3.27E-28 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 Gene3D G3DSA:3.30.460.80 2 102 3.9E-19 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 192 217 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 Gene3D G3DSA:1.10.645.20 154 512 3.6E-130 T 31-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 SUPERFAMILY SSF56762 163 512 7.59E-115 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 Pfam PF00374 Nickel-dependent hydrogenase 192 260 5.0E-12 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 N186_06555 ba9e48e0dce73a751bb471be94807acb 537 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 58 107 6.0E-7 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_04345 3a01e3bb82c17f64f680a801489849ac 337 Pfam PF06463 Molybdenum Cofactor Synthesis C 178 300 2.4E-22 T 31-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_04345 3a01e3bb82c17f64f680a801489849ac 337 Pfam PF13394 4Fe-4S single cluster domain 18 98 8.0E-8 T 31-10-2018 N186_04345 3a01e3bb82c17f64f680a801489849ac 337 Gene3D G3DSA:3.20.20.70 1 306 5.9E-76 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_04345 3a01e3bb82c17f64f680a801489849ac 337 SUPERFAMILY SSF102114 2 279 1.12E-63 T 31-10-2018 N186_04345 3a01e3bb82c17f64f680a801489849ac 337 SMART SM00729 11 210 3.7E-4 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_04345 3a01e3bb82c17f64f680a801489849ac 337 Pfam PF04055 Radical SAM superfamily 15 171 2.9E-25 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_04345 3a01e3bb82c17f64f680a801489849ac 337 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 2 304 2.0E-98 T 31-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 N186_05315 e154904cde189903395c621e4f175fe3 405 SUPERFAMILY SSF49464 18 100 1.06E-12 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily N186_05315 e154904cde189903395c621e4f175fe3 405 Gene3D G3DSA:3.40.30.10 205 330 1.4E-18 T 31-10-2018 N186_05315 e154904cde189903395c621e4f175fe3 405 Pfam PF13620 Carboxypeptidase regulatory-like domain 14 87 1.1E-9 T 31-10-2018 N186_05315 e154904cde189903395c621e4f175fe3 405 Gene3D G3DSA:2.60.40.1120 14 98 5.7E-13 T 31-10-2018 N186_05315 e154904cde189903395c621e4f175fe3 405 SUPERFAMILY SSF52833 212 321 1.26E-16 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_00965 68fa1adb535481d3d95178ae0adfd0b4 203 Gene3D G3DSA:1.10.10.10 12 74 3.0E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_00965 68fa1adb535481d3d95178ae0adfd0b4 203 SUPERFAMILY SSF55261 101 188 7.85E-11 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 N186_00965 68fa1adb535481d3d95178ae0adfd0b4 203 SUPERFAMILY SSF46785 11 72 2.77E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_00965 68fa1adb535481d3d95178ae0adfd0b4 203 Gene3D G3DSA:3.30.1360.30 75 155 3.0E-22 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 N186_00280 f0660a29750645f88ef7d5481705150c 701 SUPERFAMILY SSF51445 272 539 1.96E-19 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily N186_00280 f0660a29750645f88ef7d5481705150c 701 Gene3D G3DSA:3.20.20.80 270 559 2.8E-64 T 31-10-2018 N186_06005 948da705c82ec14df6a3b541b72a7875 572 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 16 177 5.7E-31 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 N186_06005 948da705c82ec14df6a3b541b72a7875 572 Gene3D G3DSA:3.40.50.970 189 386 7.0E-73 T 31-10-2018 N186_06005 948da705c82ec14df6a3b541b72a7875 572 SUPERFAMILY SSF52922 472 570 2.43E-14 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 N186_06005 948da705c82ec14df6a3b541b72a7875 572 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 215 447 3.0E-59 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 N186_06005 948da705c82ec14df6a3b541b72a7875 572 Gene3D G3DSA:3.40.50.920 462 570 1.5E-18 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 N186_06005 948da705c82ec14df6a3b541b72a7875 572 SUPERFAMILY SSF52518 202 455 4.58E-66 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold N186_06005 948da705c82ec14df6a3b541b72a7875 572 Gene3D G3DSA:3.40.920.10 4 188 3.0E-28 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 N186_06005 948da705c82ec14df6a3b541b72a7875 572 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 7 562 2.4E-177 T 31-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 N186_06005 948da705c82ec14df6a3b541b72a7875 572 SUPERFAMILY SSF53323 7 223 2.62E-23 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 N186_08395 77f043a556c8f41ba1f62218ac2dae23 236 Gene3D G3DSA:3.40.50.150 25 234 5.8E-32 T 31-10-2018 N186_08395 77f043a556c8f41ba1f62218ac2dae23 236 SUPERFAMILY SSF53335 25 231 2.81E-31 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_08395 77f043a556c8f41ba1f62218ac2dae23 236 Pfam PF13649 Methyltransferase domain 44 139 1.9E-15 T 31-10-2018 N186_04930 09f1f3317da03053a690b353b902aa72 398 SUPERFAMILY SSF52540 2 317 1.98E-64 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04930 09f1f3317da03053a690b353b902aa72 398 SUPERFAMILY SSF81271 324 397 4.74E-13 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 N186_04930 09f1f3317da03053a690b353b902aa72 398 Pfam PF02824 TGS domain 340 396 1.6E-6 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 N186_04930 09f1f3317da03053a690b353b902aa72 398 Pfam PF08438 GTPase of unknown function C-terminal 222 329 8.6E-37 T 31-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal N186_04930 09f1f3317da03053a690b353b902aa72 398 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 8.8E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_04930 09f1f3317da03053a690b353b902aa72 398 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 76 91 8.8E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_04930 09f1f3317da03053a690b353b902aa72 398 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 8.8E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_04930 09f1f3317da03053a690b353b902aa72 398 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 93 111 8.8E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_04930 09f1f3317da03053a690b353b902aa72 398 Gene3D G3DSA:1.10.8.470 129 217 4.3E-80 T 31-10-2018 N186_04930 09f1f3317da03053a690b353b902aa72 398 Gene3D G3DSA:3.10.20.30 321 398 2.1E-27 T 31-10-2018 IPR012675 Beta-grasp domain superfamily N186_04930 09f1f3317da03053a690b353b902aa72 398 Pfam PF01926 50S ribosome-binding GTPase 3 123 1.2E-16 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_04930 09f1f3317da03053a690b353b902aa72 398 Gene3D G3DSA:3.40.50.300 4 272 4.3E-80 T 31-10-2018 N186_05120 af70a2b92d7498916c5607a35902f657 603 Gene3D G3DSA:3.30.470.30 239 444 6.4E-72 T 31-10-2018 N186_05120 af70a2b92d7498916c5607a35902f657 603 Gene3D G3DSA:2.40.50.140 445 603 2.3E-53 T 31-10-2018 N186_05120 af70a2b92d7498916c5607a35902f657 603 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 265 273 - T 31-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 N186_05120 af70a2b92d7498916c5607a35902f657 603 SUPERFAMILY SSF56091 237 442 3.12E-52 T 31-10-2018 N186_05120 af70a2b92d7498916c5607a35902f657 603 Pfam PF04679 ATP dependent DNA ligase C terminal region 467 577 3.0E-21 T 31-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 N186_05120 af70a2b92d7498916c5607a35902f657 603 SUPERFAMILY SSF50249 451 595 3.14E-43 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_05120 af70a2b92d7498916c5607a35902f657 603 Pfam PF04675 DNA ligase N terminus 9 191 5.0E-39 T 31-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 N186_05120 af70a2b92d7498916c5607a35902f657 603 Gene3D G3DSA:1.10.3260.10 8 238 7.2E-78 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 N186_05120 af70a2b92d7498916c5607a35902f657 603 Hamap MF_00407 DNA ligase [lig]. 8 593 31.66 T 31-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 N186_05120 af70a2b92d7498916c5607a35902f657 603 SUPERFAMILY SSF117018 3 262 2.75E-69 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 N186_05120 af70a2b92d7498916c5607a35902f657 603 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 64 593 2.3E-168 T 31-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 N186_05120 af70a2b92d7498916c5607a35902f657 603 Pfam PF01068 ATP dependent DNA ligase domain 242 442 3.8E-62 T 31-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 N186_02725 7bd8c04da868930b5e10afa35ff984a8 365 Pfam PF01841 Transglutaminase-like superfamily 167 246 7.7E-5 T 31-10-2018 IPR002931 Transglutaminase-like N186_02725 7bd8c04da868930b5e10afa35ff984a8 365 SUPERFAMILY SSF54001 163 288 8.17E-9 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily N186_00045 921dbf73e4f70f7244594fca07157fcf 77 SUPERFAMILY SSF89447 1 43 1.02E-6 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_00045 921dbf73e4f70f7244594fca07157fcf 77 SMART SM00966 4 46 0.0073 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_03345 851dee78af042bb0fb85f739f42b89c5 223 SUPERFAMILY SSF55909 6 221 1.57E-54 T 31-10-2018 N186_03345 851dee78af042bb0fb85f739f42b89c5 223 Pfam PF01912 eIF-6 family 7 203 1.1E-60 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 N186_03345 851dee78af042bb0fb85f739f42b89c5 223 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 223 76.103 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 N186_03345 851dee78af042bb0fb85f739f42b89c5 223 Gene3D G3DSA:3.75.10.10 5 222 1.7E-67 T 31-10-2018 N186_03345 851dee78af042bb0fb85f739f42b89c5 223 SMART SM00654 5 203 2.9E-58 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 N186_03345 851dee78af042bb0fb85f739f42b89c5 223 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 9 222 3.1E-52 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 N186_09105 cd5a9953a0061a94a03d40c3b34a1e41 128 SUPERFAMILY SSF88723 1 124 8.41E-17 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_09105 cd5a9953a0061a94a03d40c3b34a1e41 128 Gene3D G3DSA:3.40.50.1010 1 123 4.9E-17 T 31-10-2018 N186_09105 cd5a9953a0061a94a03d40c3b34a1e41 128 Pfam PF01850 PIN domain 1 119 2.9E-16 T 31-10-2018 IPR002716 PIN domain N186_00090 89e3ca23e3539b004bd31fa0386be8ce 265 Gene3D G3DSA:3.30.930.10 30 215 6.4E-49 T 31-10-2018 N186_00090 89e3ca23e3539b004bd31fa0386be8ce 265 SUPERFAMILY SSF55681 23 216 3.48E-50 T 31-10-2018 N186_00090 89e3ca23e3539b004bd31fa0386be8ce 265 Pfam PF03099 Biotin/lipoate A/B protein ligase family 41 156 5.4E-12 T 31-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 N186_00090 89e3ca23e3539b004bd31fa0386be8ce 265 Gene3D G3DSA:2.30.30.100 217 265 3.7E-12 T 31-10-2018 N186_00090 89e3ca23e3539b004bd31fa0386be8ce 265 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 32 263 1.2E-54 T 31-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 N186_00090 89e3ca23e3539b004bd31fa0386be8ce 265 SUPERFAMILY SSF50037 219 261 5.95E-6 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal N186_00090 89e3ca23e3539b004bd31fa0386be8ce 265 Pfam PF02237 Biotin protein ligase C terminal domain 218 263 3.9E-5 T 31-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 N186_05305 70d4a8becf791e24a38ba53ad039dc43 473 Gene3D G3DSA:3.60.21.10 45 272 1.9E-17 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_05305 70d4a8becf791e24a38ba53ad039dc43 473 SUPERFAMILY SSF56300 49 255 2.89E-27 T 31-10-2018 N186_05305 70d4a8becf791e24a38ba53ad039dc43 473 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 50 254 4.0E-13 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 SMART SM00350 108 604 1.9E-238 T 31-10-2018 IPR031327 Mini-chromosome maintenance protein N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 SUPERFAMILY SSF50249 18 262 6.34E-61 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 ProSitePatterns PS00847 MCM family signature. 402 410 - T 31-10-2018 IPR018525 Mini-chromosome maintenance, conserved site GO:0003677|GO:0005524|GO:0006260 Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 SUPERFAMILY SSF52540 303 601 3.47E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 Gene3D G3DSA:1.10.10.10 609 694 9.0E-25 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 Pfam PF14551 MCM N-terminal domain 14 95 9.7E-17 T 31-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 Pfam PF00493 MCM2/3/5 family 281 601 2.0E-141 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 Gene3D G3DSA:2.40.50.140 115 264 6.0E-44 T 31-10-2018 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 473 481 7.3E-34 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 446 458 7.3E-34 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 422 435 7.3E-34 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 334 349 7.3E-34 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 394 408 7.3E-34 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 Gene3D G3DSA:2.20.28.10 139 192 6.0E-44 T 31-10-2018 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 Gene3D G3DSA:3.30.1640.10 5 106 1.0E-23 T 31-10-2018 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 Gene3D G3DSA:3.40.50.300 277 608 3.1E-139 T 31-10-2018 N186_03825 021e8b90a9c4a53740e7fb774bf6c959 696 Pfam PF17207 MCM OB domain 111 241 2.4E-37 T 31-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 N186_06300 7157709e5425ce68f605f02a2458add0 305 SUPERFAMILY SSF54631 167 293 1.26E-34 T 31-10-2018 N186_06300 7157709e5425ce68f605f02a2458add0 305 SMART SM00116 244 292 5.8E-8 T 31-10-2018 IPR000644 CBS domain N186_06300 7157709e5425ce68f605f02a2458add0 305 SMART SM00116 181 229 3.8E-13 T 31-10-2018 IPR000644 CBS domain N186_06300 7157709e5425ce68f605f02a2458add0 305 SUPERFAMILY SSF46785 6 73 7.43E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_06300 7157709e5425ce68f605f02a2458add0 305 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 5 72 2.1E-23 T 31-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 N186_06300 7157709e5425ce68f605f02a2458add0 305 Gene3D G3DSA:3.10.580.10 168 293 8.8E-35 T 31-10-2018 N186_06300 7157709e5425ce68f605f02a2458add0 305 Pfam PF00571 CBS domain 174 228 2.4E-14 T 31-10-2018 IPR000644 CBS domain N186_06300 7157709e5425ce68f605f02a2458add0 305 Pfam PF00571 CBS domain 237 289 6.7E-14 T 31-10-2018 IPR000644 CBS domain N186_06300 7157709e5425ce68f605f02a2458add0 305 PIRSF PIRSF005063 1 297 8.1E-84 T 31-10-2018 IPR016436 Uncharacterised conserved protein UCP005063, CBS-type N186_06300 7157709e5425ce68f605f02a2458add0 305 Gene3D G3DSA:1.10.10.10 10 79 2.2E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_08220 91e87c845b5e22a45374c4ee19dacd6c 134 PIRSF PIRSF004761 4 133 1.0E-20 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 N186_08220 91e87c845b5e22a45374c4ee19dacd6c 134 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 5 132 1.2E-19 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 N186_08220 91e87c845b5e22a45374c4ee19dacd6c 134 Gene3D G3DSA:3.30.2320.50 4 74 1.1E-10 T 31-10-2018 N186_08220 91e87c845b5e22a45374c4ee19dacd6c 134 Gene3D G3DSA:2.20.28.10 75 126 4.6E-23 T 31-10-2018 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 SMART SM00840 358 417 2.6E-4 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 20 315 5.7E-125 T 31-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 SUPERFAMILY SSF47323 345 474 2.09E-25 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 SUPERFAMILY SSF52374 7 315 5.38E-93 T 31-10-2018 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 223 244 8.3E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 29 40 8.3E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 65 74 8.3E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 192 210 8.3E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 6 473 7.3E-150 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 Pfam PF09190 DALR domain 359 416 1.5E-6 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 Gene3D G3DSA:1.20.120.640 308 475 1.7E-22 T 31-10-2018 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 6 476 35.408 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 N186_06075 5e9f1f75b1f62dc57b2fee08ab8316cc 478 Gene3D G3DSA:3.40.50.620 2 307 4.6E-132 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_01555 a2e6803ad61bf03ef78456f603ca5cbe 240 Gene3D G3DSA:3.60.21.10 27 238 2.6E-5 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_01555 a2e6803ad61bf03ef78456f603ca5cbe 240 SUPERFAMILY SSF56300 29 212 8.39E-9 T 31-10-2018 N186_01555 a2e6803ad61bf03ef78456f603ca5cbe 240 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 29 212 2.6E-6 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 N186_03800 a9d3df23fbeb3638dec6d49316d9df1a 135 Pfam PF05239 PRC-barrel domain 3 67 2.3E-9 T 31-10-2018 IPR027275 PRC-barrel domain N186_03800 a9d3df23fbeb3638dec6d49316d9df1a 135 SUPERFAMILY SSF50346 3 64 2.55E-8 T 31-10-2018 IPR011033 PRC-barrel-like superfamily N186_00040 32d19724cb388f65145ce5da9d8b6c31 380 Gene3D G3DSA:3.20.20.70 143 369 7.8E-21 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_00040 32d19724cb388f65145ce5da9d8b6c31 380 PIRSF PIRSF004869 2 37 14.0 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted N186_00040 32d19724cb388f65145ce5da9d8b6c31 380 PIRSF PIRSF004869 32 380 2.2E-78 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted N186_00040 32d19724cb388f65145ce5da9d8b6c31 380 Pfam PF13353 4Fe-4S single cluster domain 148 237 2.1E-5 T 31-10-2018 N186_00040 32d19724cb388f65145ce5da9d8b6c31 380 SUPERFAMILY SSF102114 138 377 1.18E-17 T 31-10-2018 N186_00040 32d19724cb388f65145ce5da9d8b6c31 380 Pfam PF04055 Radical SAM superfamily 152 312 1.4E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_01615 10ff486baaef1f20845fec34935924d8 385 Pfam PF01904 Protein of unknown function DUF72 27 244 9.3E-53 T 31-10-2018 IPR002763 Protein of unknown function DUF72 N186_01615 10ff486baaef1f20845fec34935924d8 385 SUPERFAMILY SSF117396 5 247 1.31E-70 T 31-10-2018 IPR036520 UPF0759 superfamily N186_01615 10ff486baaef1f20845fec34935924d8 385 Gene3D G3DSA:3.20.20.410 2 250 1.2E-71 T 31-10-2018 IPR036520 UPF0759 superfamily N186_09460 f1ba2c9f27f99f1db95cf412cf06906a 396 Pfam PF04055 Radical SAM superfamily 53 209 1.6E-22 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_09460 f1ba2c9f27f99f1db95cf412cf06906a 396 SUPERFAMILY SSF102114 51 356 7.32E-77 T 31-10-2018 N186_09460 f1ba2c9f27f99f1db95cf412cf06906a 396 SMART SM00729 48 248 9.3E-5 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_09460 f1ba2c9f27f99f1db95cf412cf06906a 396 Pfam PF13186 Iron-sulfur cluster-binding domain 289 349 4.8E-13 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain N186_09460 f1ba2c9f27f99f1db95cf412cf06906a 396 PIRSF PIRSF037420 43 393 3.6E-93 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E N186_09460 f1ba2c9f27f99f1db95cf412cf06906a 396 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 289 375 4.6E-14 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain N186_09460 f1ba2c9f27f99f1db95cf412cf06906a 396 Pfam PF13353 4Fe-4S single cluster domain 56 141 2.2E-7 T 31-10-2018 N186_09460 f1ba2c9f27f99f1db95cf412cf06906a 396 Gene3D G3DSA:3.20.20.70 51 343 2.5E-59 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 101 181 3.7E-31 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 10 89 3.2E-30 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 130 179 - T 31-10-2018 IPR030491 TATA-box binding protein, conserved site N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 Hamap MF_00408 TATA-box-binding protein [tbp]. 6 185 37.573 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 Gene3D G3DSA:3.30.310.10 2 91 7.7E-32 T 31-10-2018 IPR012295 TBP domain superfamily N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 SUPERFAMILY SSF55945 5 97 1.11E-29 T 31-10-2018 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 SUPERFAMILY SSF55945 99 183 1.24E-30 T 31-10-2018 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 PRINTS PR00686 Transcription initiation factor TFIID signature 103 119 1.8E-47 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 PRINTS PR00686 Transcription initiation factor TFIID signature 12 27 1.8E-47 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 PRINTS PR00686 Transcription initiation factor TFIID signature 55 73 1.8E-47 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 PRINTS PR00686 Transcription initiation factor TFIID signature 126 141 1.8E-47 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 PRINTS PR00686 Transcription initiation factor TFIID signature 36 55 1.8E-47 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 PRINTS PR00686 Transcription initiation factor TFIID signature 145 161 1.8E-47 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 N186_02405 d83b26f751a311dbc9a29917bf4eb55a 189 Gene3D G3DSA:3.30.310.10 93 185 1.3E-35 T 31-10-2018 IPR012295 TBP domain superfamily N186_01855 38cba6d1ec59864ab159e2088613986b 286 Gene3D G3DSA:3.30.540.10 1 143 3.2E-29 T 31-10-2018 N186_01855 38cba6d1ec59864ab159e2088613986b 286 Pfam PF00459 Inositol monophosphatase family 8 272 4.3E-38 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 N186_01855 38cba6d1ec59864ab159e2088613986b 286 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 31-10-2018 IPR020583 Inositol monophosphatase, metal-binding site N186_01855 38cba6d1ec59864ab159e2088613986b 286 SUPERFAMILY SSF56655 2 275 2.09E-48 T 31-10-2018 N186_01855 38cba6d1ec59864ab159e2088613986b 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 182 203 5.6E-19 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 N186_01855 38cba6d1ec59864ab159e2088613986b 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 215 239 5.6E-19 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 N186_01855 38cba6d1ec59864ab159e2088613986b 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 5.6E-19 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 N186_01855 38cba6d1ec59864ab159e2088613986b 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 137 160 5.6E-19 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 N186_01855 38cba6d1ec59864ab159e2088613986b 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 5.6E-19 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 N186_01855 38cba6d1ec59864ab159e2088613986b 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 5.6E-19 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 N186_01855 38cba6d1ec59864ab159e2088613986b 286 Gene3D G3DSA:3.40.190.80 144 270 5.1E-18 T 31-10-2018 N186_01855 38cba6d1ec59864ab159e2088613986b 286 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 218 232 - T 31-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 N186_00255 0ade60d4e06bfa19a945435de2749268 174 SUPERFAMILY SSF55811 5 170 5.42E-38 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 N186_00255 0ade60d4e06bfa19a945435de2749268 174 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 N186_00255 0ade60d4e06bfa19a945435de2749268 174 Pfam PF00293 NUDIX domain 42 150 4.6E-17 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 N186_00255 0ade60d4e06bfa19a945435de2749268 174 Gene3D G3DSA:3.90.79.10 4 172 2.5E-39 T 31-10-2018 N186_00255 0ade60d4e06bfa19a945435de2749268 174 PRINTS PR00502 NUDIX hydrolase family signature 84 99 6.3E-5 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 N186_00255 0ade60d4e06bfa19a945435de2749268 174 PRINTS PR00502 NUDIX hydrolase family signature 70 84 6.3E-5 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 N186_04430 f38165637c7d50400039750e0d64d1f5 569 SUPERFAMILY SSF47323 394 564 6.54E-38 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04430 f38165637c7d50400039750e0d64d1f5 569 Pfam PF08264 Anticodon-binding domain of tRNA 426 566 5.5E-13 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 N186_04430 f38165637c7d50400039750e0d64d1f5 569 Pfam PF09334 tRNA synthetases class I (M) 12 404 1.6E-156 T 31-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04430 f38165637c7d50400039750e0d64d1f5 569 SUPERFAMILY SSF52374 9 391 2.34E-99 T 31-10-2018 N186_04430 f38165637c7d50400039750e0d64d1f5 569 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 12 546 3.8E-161 T 31-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 N186_04430 f38165637c7d50400039750e0d64d1f5 569 Gene3D G3DSA:3.40.50.620 12 391 5.5E-151 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_04430 f38165637c7d50400039750e0d64d1f5 569 SUPERFAMILY SSF57770 146 180 4.84E-12 T 31-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_04430 f38165637c7d50400039750e0d64d1f5 569 Gene3D G3DSA:2.20.28.20 146 180 5.5E-151 T 31-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_04430 f38165637c7d50400039750e0d64d1f5 569 Gene3D G3DSA:1.10.730.10 394 545 3.8E-40 T 31-10-2018 N186_04430 f38165637c7d50400039750e0d64d1f5 569 Hamap MF_00098 Methionine--tRNA ligase [metG]. 9 557 39.27 T 31-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_04430 f38165637c7d50400039750e0d64d1f5 569 PRINTS PR01041 Methionyl-tRNA synthetase signature 94 105 3.3E-23 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 N186_04430 f38165637c7d50400039750e0d64d1f5 569 PRINTS PR01041 Methionyl-tRNA synthetase signature 46 60 3.3E-23 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 N186_04430 f38165637c7d50400039750e0d64d1f5 569 PRINTS PR01041 Methionyl-tRNA synthetase signature 13 26 3.3E-23 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 N186_04430 f38165637c7d50400039750e0d64d1f5 569 PRINTS PR01041 Methionyl-tRNA synthetase signature 297 312 3.3E-23 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 N186_04430 f38165637c7d50400039750e0d64d1f5 569 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 268 3.3E-23 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 N186_04430 f38165637c7d50400039750e0d64d1f5 569 PRINTS PR01041 Methionyl-tRNA synthetase signature 391 402 3.3E-23 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 N186_00535 69b88d8e94f86c82e8ab8cc4faaf99c8 218 Gene3D G3DSA:1.10.3720.10 2 217 2.7E-24 T 31-10-2018 IPR035906 MetI-like superfamily N186_00535 69b88d8e94f86c82e8ab8cc4faaf99c8 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 211 1.8E-12 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_00535 69b88d8e94f86c82e8ab8cc4faaf99c8 218 SUPERFAMILY SSF161098 6 205 6.67E-28 T 31-10-2018 IPR035906 MetI-like superfamily N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 Pfam PF00152 tRNA synthetases class II (D, K and N) 108 415 8.7E-87 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 PRINTS PR01042 Aspartyl-tRNA synthetase signature 376 390 1.2E-22 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 PRINTS PR01042 Aspartyl-tRNA synthetase signature 336 352 1.2E-22 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 PRINTS PR01042 Aspartyl-tRNA synthetase signature 174 186 1.2E-22 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 203 1.2E-22 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 Gene3D G3DSA:2.40.50.140 5 89 1.8E-11 T 31-10-2018 N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 421 36.494 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 SUPERFAMILY SSF50249 5 86 7.1E-9 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 7 421 1.1E-130 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 Gene3D G3DSA:3.30.930.10 94 421 2.9E-109 T 31-10-2018 N186_04490 b6e42357c2aed7043ba1f1a6126ff379 421 SUPERFAMILY SSF55681 105 415 9.56E-92 T 31-10-2018 N186_08130 e3d7f1ac732c1d44871f4b1b2a045d15 79 Gene3D G3DSA:2.10.260.10 2 47 5.7E-10 T 31-10-2018 N186_08130 e3d7f1ac732c1d44871f4b1b2a045d15 79 SMART SM00966 6 50 1.0E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08130 e3d7f1ac732c1d44871f4b1b2a045d15 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 48 3.2E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08130 e3d7f1ac732c1d44871f4b1b2a045d15 79 SUPERFAMILY SSF89447 1 51 3.4E-12 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_08130 e3d7f1ac732c1d44871f4b1b2a045d15 79 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 8.8E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_01220 851cdf38a1e7d3ab1cda7bda1d68feb8 448 Pfam PF01979 Amidohydrolase family 60 402 6.1E-45 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 N186_01220 851cdf38a1e7d3ab1cda7bda1d68feb8 448 Gene3D G3DSA:3.20.20.140 64 348 7.0E-118 T 31-10-2018 N186_01220 851cdf38a1e7d3ab1cda7bda1d68feb8 448 SUPERFAMILY SSF51556 63 352 3.11E-75 T 31-10-2018 IPR032466 Metal-dependent hydrolase N186_01220 851cdf38a1e7d3ab1cda7bda1d68feb8 448 Gene3D G3DSA:2.30.40.10 9 420 7.0E-118 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 N186_01220 851cdf38a1e7d3ab1cda7bda1d68feb8 448 SUPERFAMILY SSF51338 12 427 1.32E-27 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 N186_00995 cfc8c8362b26785f928bd42a9910a630 139 SUPERFAMILY SSF88723 6 132 3.08E-22 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_00995 cfc8c8362b26785f928bd42a9910a630 139 Pfam PF01850 PIN domain 8 131 2.7E-13 T 31-10-2018 IPR002716 PIN domain N186_00995 cfc8c8362b26785f928bd42a9910a630 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 137 10.174 T 31-10-2018 IPR022907 VapC family GO:0004540 N186_00995 cfc8c8362b26785f928bd42a9910a630 139 SMART SM00670 5 128 6.1E-4 T 31-10-2018 IPR002716 PIN domain N186_00995 cfc8c8362b26785f928bd42a9910a630 139 Gene3D G3DSA:3.40.50.1010 7 136 8.2E-13 T 31-10-2018 N186_00590 9d2c6ea8391789a4a38098c879a436ec 77 SUPERFAMILY SSF64307 4 72 1.83E-17 T 31-10-2018 IPR036868 TusA-like domain superfamily N186_00590 9d2c6ea8391789a4a38098c879a436ec 77 Gene3D G3DSA:3.30.110.40 1 74 6.9E-24 T 31-10-2018 IPR036868 TusA-like domain superfamily N186_00590 9d2c6ea8391789a4a38098c879a436ec 77 Pfam PF01206 Sulfurtransferase TusA 4 72 2.1E-17 T 31-10-2018 IPR001455 TusA-like domain N186_06380 339a868f5c98fd101aeeffa87f72e828 237 SUPERFAMILY SSF100950 4 216 6.56E-31 T 31-10-2018 IPR037171 NagB/RpiA transferase-like N186_06380 339a868f5c98fd101aeeffa87f72e828 237 Gene3D G3DSA:3.40.50.10420 36 211 2.0E-14 T 31-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily N186_06380 339a868f5c98fd101aeeffa87f72e828 237 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 5 197 7.6E-32 T 31-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase N186_08930 ead62baefb25a693ff14a19eee2bd546 243 Pfam PF00722 Glycosyl hydrolases family 16 159 197 1.8E-4 T 31-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 N186_08930 ead62baefb25a693ff14a19eee2bd546 243 Gene3D G3DSA:2.60.120.200 151 243 5.0E-10 T 31-10-2018 N186_08930 ead62baefb25a693ff14a19eee2bd546 243 SUPERFAMILY SSF49899 165 243 1.98E-7 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily N186_08930 ead62baefb25a693ff14a19eee2bd546 243 SUPERFAMILY SSF49899 9 243 2.38E-5 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily N186_00940 0b283cbec07539defb67404f63a9953c 138 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 103 6.1E-11 T 31-10-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase Reactome: R-HSA-74259 N186_00940 0b283cbec07539defb67404f63a9953c 138 SUPERFAMILY SSF52309 1 102 5.49E-17 T 31-10-2018 N186_00940 0b283cbec07539defb67404f63a9953c 138 Hamap MF_03036 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 [DNPH1]. 2 138 22.316 T 31-10-2018 IPR028607 2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 GO:0009159|GO:0070694 Reactome: R-HSA-74259 N186_00940 0b283cbec07539defb67404f63a9953c 138 Gene3D G3DSA:3.40.50.450 1 138 6.3E-39 T 31-10-2018 N186_08715 cef8f7143d0b84f146dff501d1e57afa 190 SUPERFAMILY SSF52980 6 186 3.22E-10 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_08715 cef8f7143d0b84f146dff501d1e57afa 190 Pfam PF07788 PD-(D/E)XK nuclease superfamily 116 185 1.2E-24 T 31-10-2018 IPR012431 PD-(D/E)XK nuclease N186_08715 cef8f7143d0b84f146dff501d1e57afa 190 Pfam PF12644 Protein of unknown function (DUF3782) 37 115 2.4E-24 T 31-10-2018 IPR024271 Protein of unknown function DUF3782 N186_04170 7503a0801c9ea81b43d62601868ef758 258 Gene3D G3DSA:3.40.1280.10 16 176 3.4E-42 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal N186_04170 7503a0801c9ea81b43d62601868ef758 258 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 19 240 1.8E-50 T 31-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 N186_04170 7503a0801c9ea81b43d62601868ef758 258 SUPERFAMILY SSF75217 18 177 1.64E-28 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases N186_04170 7503a0801c9ea81b43d62601868ef758 258 Pfam PF00588 SpoU rRNA Methylase family 20 168 4.6E-27 T 31-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 N186_04170 7503a0801c9ea81b43d62601868ef758 258 PIRSF PIRSF004808 15 250 3.2E-54 T 31-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 N186_00390 722e67e407a6c04a6bbe89e4cec5ff7c 340 Gene3D G3DSA:3.40.50.300 1 240 2.3E-67 T 31-10-2018 N186_00390 722e67e407a6c04a6bbe89e4cec5ff7c 340 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_00390 722e67e407a6c04a6bbe89e4cec5ff7c 340 Pfam PF13732 Domain of unknown function (DUF4162) 225 313 5.4E-9 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 N186_00390 722e67e407a6c04a6bbe89e4cec5ff7c 340 SUPERFAMILY SSF52540 11 231 2.61E-64 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00390 722e67e407a6c04a6bbe89e4cec5ff7c 340 SMART SM00382 36 220 6.2E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00390 722e67e407a6c04a6bbe89e4cec5ff7c 340 Pfam PF00005 ABC transporter 27 170 3.8E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00390 722e67e407a6c04a6bbe89e4cec5ff7c 340 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 18 314 3.7E-94 T 31-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 N186_00615 7410e6ed562a4ef523f5cd8420a39c2d 520 Gene3D G3DSA:3.40.190.10 108 380 9.9E-31 T 31-10-2018 N186_00615 7410e6ed562a4ef523f5cd8420a39c2d 520 SUPERFAMILY SSF53850 107 386 7.25E-40 T 31-10-2018 N186_00615 7410e6ed562a4ef523f5cd8420a39c2d 520 Pfam PF13416 Bacterial extracellular solute-binding protein 106 386 4.0E-20 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein N186_00615 7410e6ed562a4ef523f5cd8420a39c2d 520 Gene3D G3DSA:3.40.190.10 202 324 9.9E-31 T 31-10-2018 N186_06940 56ce24beed0cfb7632c8c25eed6cd714 232 Pfam PF04967 HTH DNA binding domain 163 214 4.7E-20 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain N186_06180 d0f34f4267e6aacea2f341e45fb7f098 323 PIRSF PIRSF004976 1 309 5.0E-91 T 31-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 N186_06180 d0f34f4267e6aacea2f341e45fb7f098 323 SUPERFAMILY SSF52402 21 250 3.31E-46 T 31-10-2018 N186_06180 d0f34f4267e6aacea2f341e45fb7f098 323 Pfam PF01171 PP-loop family 47 216 4.4E-12 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 N186_06180 d0f34f4267e6aacea2f341e45fb7f098 323 Gene3D G3DSA:3.40.50.620 1 317 1.9E-67 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_06180 d0f34f4267e6aacea2f341e45fb7f098 323 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 199 296 2.7E-22 T 31-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 391 405 1.5E-16 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 433 440 1.5E-16 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 312 1.5E-16 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 169 1.5E-16 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 13 462 2.4E-184 T 31-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 18 127 1.7E-43 T 31-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 167 4.1E-24 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 250 4.1E-24 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 305 4.1E-24 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 418 440 4.1E-24 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 390 406 4.1E-24 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 147 451 1.2E-38 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 Gene3D G3DSA:1.10.1060.10 3 140 2.4E-43 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 SUPERFAMILY SSF51971 146 398 2.71E-68 T 31-10-2018 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 SUPERFAMILY SSF46548 3 156 4.97E-36 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 Gene3D G3DSA:3.50.50.60 144 270 1.9E-36 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 Gene3D G3DSA:3.50.50.60 271 374 1.5E-19 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_07090 57014277e1dabfea37cb5457a57e8b6b 469 Gene3D G3DSA:3.50.50.60 375 468 1.3E-11 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_09640 13f4299fd111a6af070da13f53efe2d6 509 Gene3D G3DSA:3.40.50.2300 174 404 4.8E-67 T 31-10-2018 N186_09640 13f4299fd111a6af070da13f53efe2d6 509 Pfam PF13458 Periplasmic binding protein 34 408 4.4E-49 T 31-10-2018 IPR028081 Leucine-binding protein domain N186_09640 13f4299fd111a6af070da13f53efe2d6 509 Gene3D G3DSA:3.40.50.2300 105 402 4.8E-67 T 31-10-2018 N186_09640 13f4299fd111a6af070da13f53efe2d6 509 SUPERFAMILY SSF53822 33 408 3.4E-53 T 31-10-2018 IPR028082 Periplasmic binding protein-like I N186_09075 778b223e617dd8175c9aa54f47a445a9 246 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_09075 778b223e617dd8175c9aa54f47a445a9 246 Gene3D G3DSA:3.40.50.300 2 238 2.9E-65 T 31-10-2018 N186_09075 778b223e617dd8175c9aa54f47a445a9 246 Pfam PF00005 ABC transporter 22 164 1.2E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09075 778b223e617dd8175c9aa54f47a445a9 246 SMART SM00382 30 220 1.7E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_09075 778b223e617dd8175c9aa54f47a445a9 246 SUPERFAMILY SSF52540 6 227 4.78E-62 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00275 8172e7ce29eee3696135b6c6553c909d 234 Pfam PF00106 short chain dehydrogenase 3 182 1.4E-42 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00275 8172e7ce29eee3696135b6c6553c909d 234 SUPERFAMILY SSF51735 3 231 8.28E-52 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_00275 8172e7ce29eee3696135b6c6553c909d 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 2.7E-5 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00275 8172e7ce29eee3696135b6c6553c909d 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 2.7E-5 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00275 8172e7ce29eee3696135b6c6553c909d 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 2.7E-5 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00275 8172e7ce29eee3696135b6c6553c909d 234 Gene3D G3DSA:3.40.50.720 2 234 1.9E-55 T 31-10-2018 N186_00275 8172e7ce29eee3696135b6c6553c909d 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.5E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00275 8172e7ce29eee3696135b6c6553c909d 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 3.5E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00275 8172e7ce29eee3696135b6c6553c909d 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.5E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00275 8172e7ce29eee3696135b6c6553c909d 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 3.5E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_03670 68853732c2889771aade776c66811ada 610 SMART SM00490 313 391 2.7E-9 T 31-10-2018 IPR001650 Helicase, C-terminal N186_03670 68853732c2889771aade776c66811ada 610 SUPERFAMILY SSF52540 19 392 4.32E-24 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03670 68853732c2889771aade776c66811ada 610 Gene3D G3DSA:3.40.50.300 255 428 6.7E-20 T 31-10-2018 N186_03670 68853732c2889771aade776c66811ada 610 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 24 408 2.7E-42 T 31-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core N186_03670 68853732c2889771aade776c66811ada 610 Pfam PF00271 Helicase conserved C-terminal domain 295 389 9.9E-10 T 31-10-2018 IPR001650 Helicase, C-terminal N186_03690 9c2270e3de6bcc8de09e09cbb7cddca3 269 SUPERFAMILY SSF56024 112 261 1.73E-14 T 31-10-2018 N186_03690 9c2270e3de6bcc8de09e09cbb7cddca3 269 Gene3D G3DSA:3.30.870.10 82 258 8.8E-13 T 31-10-2018 N186_03690 9c2270e3de6bcc8de09e09cbb7cddca3 269 Pfam PF13091 PLD-like domain 121 256 1.3E-10 T 31-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 N186_09335 3a73a901286e1fd515c79dbfa4e2742e 715 Gene3D G3DSA:3.40.190.10 46 107 4.4E-50 T 31-10-2018 N186_09335 3a73a901286e1fd515c79dbfa4e2742e 715 SUPERFAMILY SSF53850 44 425 7.06E-53 T 31-10-2018 N186_09335 3a73a901286e1fd515c79dbfa4e2742e 715 SUPERFAMILY SSF53850 441 705 2.17E-24 T 31-10-2018 N186_09335 3a73a901286e1fd515c79dbfa4e2742e 715 Gene3D G3DSA:3.10.105.10 108 267 4.4E-50 T 31-10-2018 N186_09335 3a73a901286e1fd515c79dbfa4e2742e 715 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 487 703 8.4E-11 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain N186_09335 3a73a901286e1fd515c79dbfa4e2742e 715 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 47 265 1.3E-44 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain N186_07270 b9cec1de5c60c1c7b32330e085e32efa 394 SMART SM00547 281 305 0.0026 T 31-10-2018 IPR001876 Zinc finger, RanBP2-type N186_07270 b9cec1de5c60c1c7b32330e085e32efa 394 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 283 302 - T 31-10-2018 IPR001876 Zinc finger, RanBP2-type N186_07270 b9cec1de5c60c1c7b32330e085e32efa 394 Gene3D G3DSA:4.10.1060.10 272 310 1.0E-5 T 31-10-2018 N186_07270 b9cec1de5c60c1c7b32330e085e32efa 394 SUPERFAMILY SSF90209 275 307 9.42E-5 T 31-10-2018 IPR036443 Zinc finger, RanBP2-type superfamily N186_03600 b626eae7b6bc1e38c9b30564b3f51f95 298 SUPERFAMILY SSF52540 2 292 4.68E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03600 b626eae7b6bc1e38c9b30564b3f51f95 298 Pfam PF13614 AAA domain 2 184 3.3E-26 T 31-10-2018 IPR025669 AAA domain N186_03600 b626eae7b6bc1e38c9b30564b3f51f95 298 Gene3D G3DSA:3.40.50.300 1 294 7.5E-46 T 31-10-2018 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 SUPERFAMILY SSF52540 3 248 3.58E-76 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 SUPERFAMILY SSF50465 324 428 3.6E-37 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 431 7.1E-205 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 SUPERFAMILY SSF50447 225 321 7.28E-29 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 Pfam PF03144 Elongation factor Tu domain 2 247 313 1.6E-16 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 Gene3D G3DSA:2.40.30.10 322 428 6.0E-40 T 31-10-2018 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 PRINTS PR00315 GTP-binding elongation factor signature 9 22 5.0E-22 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 PRINTS PR00315 GTP-binding elongation factor signature 88 98 5.0E-22 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 PRINTS PR00315 GTP-binding elongation factor signature 104 115 5.0E-22 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 PRINTS PR00315 GTP-binding elongation factor signature 68 76 5.0E-22 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 PRINTS PR00315 GTP-binding elongation factor signature 148 157 5.0E-22 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 Gene3D G3DSA:3.40.50.300 1 225 3.1E-90 T 31-10-2018 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 Gene3D G3DSA:2.40.30.10 228 321 5.5E-37 T 31-10-2018 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 Pfam PF00009 Elongation factor Tu GTP binding domain 5 214 7.3E-53 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 61 76 - T 31-10-2018 IPR031157 Tr-type G domain, conserved site N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 Pfam PF03143 Elongation factor Tu C-terminal domain 321 427 1.7E-35 T 31-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal N186_04555 4e67da0fbf1a3e5a763a2ce9d2cc494d 433 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 430 61.756 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 N186_07310 f8aece7ee7e307819718fc8790d3ba61 443 SUPERFAMILY SSF51649 135 439 2.36E-108 T 31-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 N186_07310 f8aece7ee7e307819718fc8790d3ba61 443 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 9 438 51.693 T 31-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 N186_07310 f8aece7ee7e307819718fc8790d3ba61 443 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 11 131 3.5E-44 T 31-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 N186_07310 f8aece7ee7e307819718fc8790d3ba61 443 SUPERFAMILY SSF54966 20 135 2.22E-35 T 31-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 N186_07310 f8aece7ee7e307819718fc8790d3ba61 443 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 437 1.4E-193 T 31-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 N186_07310 f8aece7ee7e307819718fc8790d3ba61 443 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 183 191 - T 31-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 N186_07310 f8aece7ee7e307819718fc8790d3ba61 443 Gene3D G3DSA:3.20.20.110 136 437 5.6E-121 T 31-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 N186_07310 f8aece7ee7e307819718fc8790d3ba61 443 Gene3D G3DSA:3.30.70.150 3 135 3.2E-42 T 31-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 N186_07310 f8aece7ee7e307819718fc8790d3ba61 443 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 141 437 5.4E-96 T 31-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 N186_05000 47154fa6ecafca2c9a25b44b1cb9fa97 469 SUPERFAMILY SSF52540 34 422 6.12E-13 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05000 47154fa6ecafca2c9a25b44b1cb9fa97 469 Gene3D G3DSA:3.40.50.300 313 449 6.9E-8 T 31-10-2018 N186_05000 47154fa6ecafca2c9a25b44b1cb9fa97 469 Pfam PF06733 DEAD_2 98 184 1.6E-4 T 31-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 N186_05000 47154fa6ecafca2c9a25b44b1cb9fa97 469 Gene3D G3DSA:3.40.50.300 12 233 1.5E-16 T 31-10-2018 N186_05000 47154fa6ecafca2c9a25b44b1cb9fa97 469 SMART SM00491 320 436 0.0035 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 N186_02315 5f624146e4122044431f18c514c8925b 138 SUPERFAMILY SSF50249 14 138 3.51E-36 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_02315 5f624146e4122044431f18c514c8925b 138 Pfam PF00164 Ribosomal protein S12/S23 23 136 1.3E-46 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02315 5f624146e4122044431f18c514c8925b 138 PRINTS PR01034 Ribosomal protein S12 signature 70 89 2.8E-5 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02315 5f624146e4122044431f18c514c8925b 138 PRINTS PR01034 Ribosomal protein S12 signature 53 68 2.8E-5 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02315 5f624146e4122044431f18c514c8925b 138 PRINTS PR01034 Ribosomal protein S12 signature 38 53 2.8E-5 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02315 5f624146e4122044431f18c514c8925b 138 PIRSF PIRSF002133 10 138 8.9E-35 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02315 5f624146e4122044431f18c514c8925b 138 ProSitePatterns PS00055 Ribosomal protein S12 signature. 54 61 - T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02315 5f624146e4122044431f18c514c8925b 138 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 1 138 8.0E-75 T 31-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02315 5f624146e4122044431f18c514c8925b 138 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 138 40.131 T 31-10-2018 IPR022863 Ribosomal protein S12, archaea N186_02315 5f624146e4122044431f18c514c8925b 138 Gene3D G3DSA:2.40.50.140 19 138 6.3E-48 T 31-10-2018 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 Pfam PF00118 TCP-1/cpn60 chaperonin family 46 537 1.9E-186 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 19 536 6.3E-238 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 70 88 7.3E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 100 119 7.3E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 384 406 7.3E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 418 430 7.3E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 48 64 7.3E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 Gene3D G3DSA:1.10.560.10 39 533 9.4E-211 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 SUPERFAMILY SSF54849 158 415 6.1E-27 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 51 63 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 Gene3D G3DSA:3.50.7.10 228 379 9.4E-211 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 72 88 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 Gene3D G3DSA:3.30.260.10 157 415 9.4E-211 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 SUPERFAMILY SSF48592 29 536 3.27E-94 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 100 108 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_04640 4b3c90c15cdbba4c6f7b63f40e8a0c83 560 SUPERFAMILY SSF52029 223 389 6.07E-63 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily N186_09130 c45b83785c058dff1c601fcbe5984762 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.3E-43 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09130 c45b83785c058dff1c601fcbe5984762 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.3E-43 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09130 c45b83785c058dff1c601fcbe5984762 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.3E-43 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09130 c45b83785c058dff1c601fcbe5984762 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 7.3E-43 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09130 c45b83785c058dff1c601fcbe5984762 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.3E-43 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09130 c45b83785c058dff1c601fcbe5984762 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.3E-43 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09130 c45b83785c058dff1c601fcbe5984762 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.2E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09130 c45b83785c058dff1c601fcbe5984762 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 9.2E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09130 c45b83785c058dff1c601fcbe5984762 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 9.2E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09130 c45b83785c058dff1c601fcbe5984762 301 SUPERFAMILY SSF51735 6 249 4.93E-82 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_09130 c45b83785c058dff1c601fcbe5984762 301 Gene3D G3DSA:3.40.50.720 1 261 6.0E-83 T 31-10-2018 N186_09130 c45b83785c058dff1c601fcbe5984762 301 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 248 1.4E-69 T 31-10-2018 N186_09130 c45b83785c058dff1c601fcbe5984762 301 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 31-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 N186_03210 e8ef549d61501d72af2201ff842307ac 190 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 184 4.4E-40 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 N186_03210 e8ef549d61501d72af2201ff842307ac 190 Gene3D G3DSA:3.40.920.10 3 189 6.1E-61 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 N186_03210 e8ef549d61501d72af2201ff842307ac 190 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 6 188 2.4E-63 T 31-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 N186_03210 e8ef549d61501d72af2201ff842307ac 190 SUPERFAMILY SSF53323 5 188 5.1E-50 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 N186_03810 96c7d7d0d0f378c0dc6e8f8f1965becc 61 SUPERFAMILY SSF57716 6 55 4.56E-14 T 31-10-2018 N186_03810 96c7d7d0d0f378c0dc6e8f8f1965becc 61 Gene3D G3DSA:2.30.170.20 2 61 2.1E-24 T 31-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily N186_03810 96c7d7d0d0f378c0dc6e8f8f1965becc 61 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 56 25.1 T 31-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03810 96c7d7d0d0f378c0dc6e8f8f1965becc 61 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 31-10-2018 IPR023442 Ribosomal protein L24e, conserved site N186_03810 96c7d7d0d0f378c0dc6e8f8f1965becc 61 Pfam PF01246 Ribosomal protein L24e 3 59 2.2E-20 T 31-10-2018 IPR000988 Ribosomal protein L24e-related N186_03810 96c7d7d0d0f378c0dc6e8f8f1965becc 61 SMART SM00746 7 45 8.7E-8 T 31-10-2018 IPR011017 TRASH domain N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 2 484 5.8E-150 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 Pfam PF09239 Topoisomerase VI B subunit, transducer 307 463 1.6E-56 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 SUPERFAMILY SSF54211 306 465 1.06E-49 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 SUPERFAMILY SSF46946 228 301 8.11E-9 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 Gene3D G3DSA:3.30.230.10 306 511 1.5E-63 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 PIRSF PIRSF006553 1 511 7.7E-189 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 Gene3D G3DSA:3.30.565.10 1 225 2.1E-70 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 SMART SM00387 25 148 1.2E-9 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 130 2.1E-13 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 305 491 9.0E-58 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 2 502 27.326 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 SUPERFAMILY SSF55874 14 218 1.57E-37 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily N186_04800 64f60e9bf2e7e8e2135be5258fb36f53 511 Gene3D G3DSA:1.10.8.50 227 305 3.1E-20 T 31-10-2018 N186_09550 8fa751303b7bcb239548c11b4e5bdbe7 37 Pfam PF05168 HEPN domain 1 33 8.8E-7 T 31-10-2018 IPR007842 HEPN domain N186_09550 8fa751303b7bcb239548c11b4e5bdbe7 37 Gene3D G3DSA:1.20.120.330 1 36 8.1E-6 T 31-10-2018 N186_09550 8fa751303b7bcb239548c11b4e5bdbe7 37 SUPERFAMILY SSF81593 1 33 1.14E-6 T 31-10-2018 N186_02855 1493d246c71f1f023f9ff91b0902958e 246 Pfam PF01163 RIO1 family 79 187 2.3E-4 T 31-10-2018 N186_02855 1493d246c71f1f023f9ff91b0902958e 246 Gene3D G3DSA:1.10.510.10 42 201 1.0E-7 T 31-10-2018 N186_02855 1493d246c71f1f023f9ff91b0902958e 246 SUPERFAMILY SSF56112 47 205 5.57E-17 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily N186_02855 1493d246c71f1f023f9ff91b0902958e 246 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 50 71 - T 31-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 N186_06680 0cb96331046998c7c393ca480dfa9995 391 Pfam PF04734 Neutral/alkaline non-lysosomal ceramidase, N-terminal 1 177 1.4E-19 T 31-10-2018 IPR031329 Neutral/alkaline non-lysosomal ceramidase, N-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119|Reactome: R-HSA-1660662 N186_09675 425d5ea81364e3c90e9d4990ab594356 265 Gene3D G3DSA:3.40.50.1820 2 262 8.1E-60 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_09675 425d5ea81364e3c90e9d4990ab594356 265 SUPERFAMILY SSF53474 4 261 1.29E-58 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_09675 425d5ea81364e3c90e9d4990ab594356 265 PRINTS PR00412 Epoxide hydrolase signature 48 63 7.3E-5 T 31-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 N186_09675 425d5ea81364e3c90e9d4990ab594356 265 PRINTS PR00412 Epoxide hydrolase signature 237 259 7.3E-5 T 31-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 N186_09675 425d5ea81364e3c90e9d4990ab594356 265 PRINTS PR00412 Epoxide hydrolase signature 205 221 7.3E-5 T 31-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 N186_09675 425d5ea81364e3c90e9d4990ab594356 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 5.1E-12 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_09675 425d5ea81364e3c90e9d4990ab594356 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 5.1E-12 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_09675 425d5ea81364e3c90e9d4990ab594356 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 5.1E-12 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_09675 425d5ea81364e3c90e9d4990ab594356 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 5.1E-12 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_09675 425d5ea81364e3c90e9d4990ab594356 265 Pfam PF00561 alpha/beta hydrolase fold 23 125 1.4E-17 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 PRINTS PR01042 Aspartyl-tRNA synthetase signature 392 406 1.5E-15 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 PRINTS PR01042 Aspartyl-tRNA synthetase signature 352 368 1.5E-15 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 1.5E-15 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 PRINTS PR01042 Aspartyl-tRNA synthetase signature 188 200 1.5E-15 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 SUPERFAMILY SSF55681 117 431 1.21E-85 T 31-10-2018 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 Pfam PF01336 OB-fold nucleic acid binding domain 27 102 7.0E-11 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 Pfam PF00152 tRNA synthetases class II (D, K and N) 117 431 9.4E-89 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 SUPERFAMILY SSF50249 16 105 3.21E-19 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 22 435 6.7E-125 T 31-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 Gene3D G3DSA:2.40.50.140 14 109 8.8E-20 T 31-10-2018 N186_05960 49802a8dbd25c98d8ddc5b26a040f816 437 Gene3D G3DSA:3.30.930.10 111 437 5.0E-110 T 31-10-2018 N186_05855 6ad79617008b00a62c2a5bbc58af0ad8 363 SUPERFAMILY SSF53756 21 288 4.92E-8 T 31-10-2018 N186_05855 6ad79617008b00a62c2a5bbc58af0ad8 363 Pfam PF04007 Protein of unknown function (DUF354) 20 310 7.9E-28 T 31-10-2018 IPR007152 Protein of unknown function DUF354 N186_05855 6ad79617008b00a62c2a5bbc58af0ad8 363 PIRSF PIRSF005357 2 352 1.2E-59 T 31-10-2018 IPR007152 Protein of unknown function DUF354 N186_08410 ba04e56d4aece8412e5294e458acf333 417 PRINTS PR00723 Subtilisin serine protease family (S8) signature 130 149 8.9E-19 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related N186_08410 ba04e56d4aece8412e5294e458acf333 417 PRINTS PR00723 Subtilisin serine protease family (S8) signature 170 183 8.9E-19 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related N186_08410 ba04e56d4aece8412e5294e458acf333 417 PRINTS PR00723 Subtilisin serine protease family (S8) signature 342 358 8.9E-19 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related N186_08410 ba04e56d4aece8412e5294e458acf333 417 SUPERFAMILY SSF52743 103 415 2.88E-81 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 N186_08410 ba04e56d4aece8412e5294e458acf333 417 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 343 353 - T 31-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site N186_08410 ba04e56d4aece8412e5294e458acf333 417 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 174 184 - T 31-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site N186_08410 ba04e56d4aece8412e5294e458acf333 417 Gene3D G3DSA:3.40.50.200 97 417 1.5E-98 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 N186_08410 ba04e56d4aece8412e5294e458acf333 417 Pfam PF00082 Subtilase family 132 406 3.2E-42 T 31-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 N186_00120 3c43928520bd2a5d7ca4e7dfd7538c7e 217 Gene3D G3DSA:3.40.225.10 1 210 8.4E-66 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily N186_00120 3c43928520bd2a5d7ca4e7dfd7538c7e 217 SUPERFAMILY SSF53639 2 205 2.75E-59 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily N186_00120 3c43928520bd2a5d7ca4e7dfd7538c7e 217 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 183 4.7E-48 T 31-10-2018 IPR001303 Class II aldolase/adducin N-terminal N186_00120 3c43928520bd2a5d7ca4e7dfd7538c7e 217 SMART SM01007 8 184 4.3E-60 T 31-10-2018 IPR001303 Class II aldolase/adducin N-terminal N186_00660 ba5c83e18945f76c4c96f17a8f9dcddc 588 Gene3D G3DSA:3.60.9.10 2 212 3.3E-60 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily N186_00660 ba5c83e18945f76c4c96f17a8f9dcddc 588 SUPERFAMILY SSF48310 212 581 3.79E-93 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_00660 ba5c83e18945f76c4c96f17a8f9dcddc 588 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 206 9.4E-65 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_00660 ba5c83e18945f76c4c96f17a8f9dcddc 588 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 221 577 6.5E-64 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_00660 ba5c83e18945f76c4c96f17a8f9dcddc 588 Gene3D G3DSA:1.10.599.10 240 579 1.0E-57 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 N186_00660 ba5c83e18945f76c4c96f17a8f9dcddc 588 Gene3D G3DSA:1.10.569.10 242 436 1.0E-57 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 N186_00660 ba5c83e18945f76c4c96f17a8f9dcddc 588 SUPERFAMILY SSF56228 5 210 1.28E-57 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily N186_00660 ba5c83e18945f76c4c96f17a8f9dcddc 588 SMART SM00790 8 208 1.6E-76 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_05250 2d2a94407cc34a4e4ccada5a7409defe 421 SUPERFAMILY SSF103473 16 407 6.41E-52 T 31-10-2018 IPR036259 MFS transporter superfamily N186_05250 2d2a94407cc34a4e4ccada5a7409defe 421 Pfam PF07690 Major Facilitator Superfamily 36 337 3.0E-28 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_05250 2d2a94407cc34a4e4ccada5a7409defe 421 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 89 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 N186_05250 2d2a94407cc34a4e4ccada5a7409defe 421 Gene3D G3DSA:1.20.1250.20 234 417 3.0E-17 T 31-10-2018 N186_05250 2d2a94407cc34a4e4ccada5a7409defe 421 Gene3D G3DSA:1.20.1250.20 19 212 2.0E-25 T 31-10-2018 N186_09445 aa62ced3775de8e89256a5ea273b8b11 246 Gene3D G3DSA:3.40.50.2020 57 236 9.4E-12 T 31-10-2018 N186_09445 aa62ced3775de8e89256a5ea273b8b11 246 SUPERFAMILY SSF53271 86 234 2.21E-10 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_05295 7be3c814340605420be1974cd93fdc65 342 Gene3D G3DSA:3.40.50.720 4 334 8.6E-146 T 31-10-2018 N186_05295 7be3c814340605420be1974cd93fdc65 342 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 154 161 - T 31-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 332 4.2E-135 T 31-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 320 2.9E-64 T 31-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 SMART SM00846 3 156 2.3E-92 T 31-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 SUPERFAMILY SSF55347 156 321 4.17E-68 T 31-10-2018 N186_05295 7be3c814340605420be1974cd93fdc65 342 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 106 4.0E-34 T 31-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 PIRSF PIRSF000149 1 341 6.8E-133 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 SUPERFAMILY SSF51735 1 181 3.85E-62 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_05295 7be3c814340605420be1974cd93fdc65 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 177 193 5.1E-40 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 113 126 5.1E-40 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 234 251 5.1E-40 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 150 168 5.1E-40 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 274 289 5.1E-40 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05295 7be3c814340605420be1974cd93fdc65 342 Gene3D G3DSA:3.30.360.10 155 322 8.6E-146 T 31-10-2018 N186_06345 69b67974452415c5f949c451a3345fdd 557 SMART SM00873 93 251 1.2E-12 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 N186_06345 69b67974452415c5f949c451a3345fdd 557 SUPERFAMILY SSF46955 273 344 3.57E-15 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily N186_06345 69b67974452415c5f949c451a3345fdd 557 SUPERFAMILY SSF46955 4 69 6.59E-5 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily N186_06345 69b67974452415c5f949c451a3345fdd 557 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 543 31.552 T 31-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 N186_06345 69b67974452415c5f949c451a3345fdd 557 SUPERFAMILY SSF55681 338 546 2.98E-41 T 31-10-2018 N186_06345 69b67974452415c5f949c451a3345fdd 557 Pfam PF03484 tRNA synthetase B5 domain 278 340 9.2E-13 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 N186_06345 69b67974452415c5f949c451a3345fdd 557 Pfam PF01409 tRNA synthetases class II core domain (F) 350 502 8.6E-5 T 31-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 N186_06345 69b67974452415c5f949c451a3345fdd 557 Gene3D G3DSA:3.30.56.10 1 75 1.6E-13 T 31-10-2018 N186_06345 69b67974452415c5f949c451a3345fdd 557 Gene3D G3DSA:3.30.930.10 357 545 6.4E-45 T 31-10-2018 N186_06345 69b67974452415c5f949c451a3345fdd 557 Gene3D G3DSA:3.50.40.10 76 269 3.4E-57 T 31-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 N186_06345 69b67974452415c5f949c451a3345fdd 557 Pfam PF03483 B3/4 domain 94 238 8.8E-12 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 N186_06345 69b67974452415c5f949c451a3345fdd 557 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 544 2.3E-151 T 31-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 N186_06345 69b67974452415c5f949c451a3345fdd 557 Gene3D G3DSA:3.30.56.10 270 340 7.2E-19 T 31-10-2018 N186_06345 69b67974452415c5f949c451a3345fdd 557 SMART SM00874 271 340 1.1E-15 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 N186_03325 47afacc86b5e83a25fb97518a5b54042 163 SUPERFAMILY SSF46785 4 150 2.45E-51 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_03325 47afacc86b5e83a25fb97518a5b54042 163 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 36.056 T 31-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 N186_03325 47afacc86b5e83a25fb97518a5b54042 163 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 7 116 3.0E-32 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03325 47afacc86b5e83a25fb97518a5b54042 163 SMART SM01413 3 139 1.8E-79 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03325 47afacc86b5e83a25fb97518a5b54042 163 Pfam PF01090 Ribosomal protein S19e 6 138 3.3E-51 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03325 47afacc86b5e83a25fb97518a5b54042 163 Gene3D G3DSA:1.10.10.2700 1 150 3.3E-54 T 31-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03540 d63f8c279bba39b78754f6c89b67d982 371 Gene3D G3DSA:3.40.50.261 231 371 2.5E-43 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_03540 d63f8c279bba39b78754f6c89b67d982 371 Pfam PF08442 ATP-grasp domain 3 191 3.2E-37 T 31-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 N186_03540 d63f8c279bba39b78754f6c89b67d982 371 Gene3D G3DSA:3.30.1490.20 21 97 4.6E-47 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 N186_03540 d63f8c279bba39b78754f6c89b67d982 371 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 246 271 - T 31-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_03540 d63f8c279bba39b78754f6c89b67d982 371 PIRSF PIRSF001554 1 371 1.0E-109 T 31-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 N186_03540 d63f8c279bba39b78754f6c89b67d982 371 SUPERFAMILY SSF52210 234 369 2.75E-39 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_03540 d63f8c279bba39b78754f6c89b67d982 371 Gene3D G3DSA:3.30.470.20 3 211 4.6E-47 T 31-10-2018 N186_03540 d63f8c279bba39b78754f6c89b67d982 371 SUPERFAMILY SSF56059 1 210 9.77E-39 T 31-10-2018 N186_03540 d63f8c279bba39b78754f6c89b67d982 371 Pfam PF00549 CoA-ligase 253 366 4.0E-13 T 31-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_02510 d283b35eeae486245630711647d0dddc 163 Pfam PF04027 Domain of unknown function (DUF371) 13 144 6.6E-41 T 31-10-2018 IPR007171 Protein of unknown function DUF371 N186_02510 d283b35eeae486245630711647d0dddc 163 Gene3D G3DSA:2.60.120.630 7 152 1.2E-47 T 31-10-2018 IPR023131 Mth639-like domain superfamily N186_02910 eaf2cdea7fc3694e0ab967b2dec219e5 307 SMART SM00530 115 170 4.8E-8 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 N186_02910 eaf2cdea7fc3694e0ab967b2dec219e5 307 Gene3D G3DSA:1.10.260.40 109 216 2.7E-10 T 31-10-2018 N186_02910 eaf2cdea7fc3694e0ab967b2dec219e5 307 SUPERFAMILY SSF47413 112 170 3.75E-10 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 N186_02910 eaf2cdea7fc3694e0ab967b2dec219e5 307 Pfam PF01381 Helix-turn-helix 116 164 8.4E-10 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 N186_02910 eaf2cdea7fc3694e0ab967b2dec219e5 307 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 1 293 15.311 T 31-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 N186_00525 c8b9e351f73d4f2639d1e51ab7c12260 352 Gene3D G3DSA:1.10.10.10 7 119 1.3E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_00525 c8b9e351f73d4f2639d1e51ab7c12260 352 SUPERFAMILY SSF46785 24 133 6.46E-20 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_00525 c8b9e351f73d4f2639d1e51ab7c12260 352 Gene3D G3DSA:3.40.190.10 199 305 3.9E-8 T 31-10-2018 N186_00525 c8b9e351f73d4f2639d1e51ab7c12260 352 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 28 88 1.3E-12 T 31-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 N186_00525 c8b9e351f73d4f2639d1e51ab7c12260 352 Pfam PF12727 PBP superfamily domain 138 327 6.5E-49 T 31-10-2018 IPR024370 PBP domain N186_00525 c8b9e351f73d4f2639d1e51ab7c12260 352 SUPERFAMILY SSF53850 187 340 3.15E-12 T 31-10-2018 N186_02320 540466567faaae4e4c7caec6da1dff1a 149 Pfam PF13184 NusA-like KH domain 52 97 1.5E-7 T 31-10-2018 IPR025249 KH domain, NusA-like GO:0003723 N186_02320 540466567faaae4e4c7caec6da1dff1a 149 Gene3D G3DSA:3.30.300.20 3 76 2.0E-21 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta N186_02320 540466567faaae4e4c7caec6da1dff1a 149 SUPERFAMILY SSF54814 22 76 1.05E-5 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 N186_02320 540466567faaae4e4c7caec6da1dff1a 149 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 5 146 26.39 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal N186_02320 540466567faaae4e4c7caec6da1dff1a 149 Gene3D G3DSA:3.30.300.20 78 146 5.3E-21 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta N186_02320 540466567faaae4e4c7caec6da1dff1a 149 SUPERFAMILY SSF54814 80 142 4.05E-10 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 N186_02320 540466567faaae4e4c7caec6da1dff1a 149 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 8 145 2.1E-34 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal N186_04265 8b3bf526240d13403b4bb9d932e230d8 121 PIRSF PIRSF004878 1 110 2.8E-33 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 N186_04265 8b3bf526240d13403b4bb9d932e230d8 121 Gene3D G3DSA:1.20.5.420 1 57 2.2E-13 T 31-10-2018 N186_04265 8b3bf526240d13403b4bb9d932e230d8 121 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 4 104 21.908 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 N186_04265 8b3bf526240d13403b4bb9d932e230d8 121 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 15 95 8.4E-17 T 31-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 N186_04265 8b3bf526240d13403b4bb9d932e230d8 121 Gene3D G3DSA:2.20.25.200 59 107 1.5E-17 T 31-10-2018 N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 Gene3D G3DSA:2.40.50.140 60 147 3.1E-23 T 31-10-2018 N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 SUPERFAMILY SSF110324 2 60 1.33E-11 T 31-10-2018 N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 Pfam PF00013 KH domain 152 207 1.4E-8 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 SUPERFAMILY SSF54791 149 227 1.2E-18 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 SUPERFAMILY SSF50249 60 152 1.34E-18 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 SMART SM00316 65 139 8.3E-7 T 31-10-2018 IPR022967 RNA-binding domain, S1 N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 Gene3D G3DSA:2.40.50.100 1 59 2.3E-16 T 31-10-2018 N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 6 232 38.593 T 31-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 SMART SM00322 146 211 5.2E-7 T 31-10-2018 IPR004087 K Homology domain GO:0003676 N186_03860 43ee66f8e78db6f26ecc6673d0701c8a 232 Gene3D G3DSA:3.30.1370.10 149 232 9.0E-31 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 N186_09320 a795ddb59d81cbc4af297d20bec53b90 333 SUPERFAMILY SSF52540 40 327 5.11E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09320 a795ddb59d81cbc4af297d20bec53b90 333 Pfam PF00005 ABC transporter 34 193 1.2E-26 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09320 a795ddb59d81cbc4af297d20bec53b90 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 309 5.1E-20 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_09320 a795ddb59d81cbc4af297d20bec53b90 333 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_09320 a795ddb59d81cbc4af297d20bec53b90 333 SMART SM00382 39 243 2.4E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_09320 a795ddb59d81cbc4af297d20bec53b90 333 Gene3D G3DSA:3.40.50.300 8 333 2.5E-92 T 31-10-2018 N186_09320 a795ddb59d81cbc4af297d20bec53b90 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 244 329 1.5E-27 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_02180 6781c0eaacf21d5477929869b87f74ae 123 SMART SM00960 11 101 4.8E-16 T 31-10-2018 IPR004942 Roadblock/LAMTOR2 domain N186_02180 6781c0eaacf21d5477929869b87f74ae 123 Gene3D G3DSA:3.30.450.30 9 123 6.2E-19 T 31-10-2018 N186_02180 6781c0eaacf21d5477929869b87f74ae 123 Pfam PF03259 Roadblock/LC7 domain 13 101 2.4E-11 T 31-10-2018 IPR004942 Roadblock/LAMTOR2 domain N186_02180 6781c0eaacf21d5477929869b87f74ae 123 SUPERFAMILY SSF103196 7 122 6.67E-16 T 31-10-2018 N186_06915 e0327b721f33702cd8035d1d2b6aac1d 304 PRINTS PR01874 DNA repair protein radA signature 206 234 6.8E-7 T 31-10-2018 N186_06915 e0327b721f33702cd8035d1d2b6aac1d 304 PRINTS PR01874 DNA repair protein radA signature 99 116 6.8E-7 T 31-10-2018 N186_06915 e0327b721f33702cd8035d1d2b6aac1d 304 PRINTS PR01874 DNA repair protein radA signature 57 85 6.8E-7 T 31-10-2018 N186_06915 e0327b721f33702cd8035d1d2b6aac1d 304 TIGRFAM TIGR03881 KaiC_arch_4: KaiC domain protein, PAE1156 family 46 275 8.0E-114 T 31-10-2018 IPR022443 KaiC-related N186_06915 e0327b721f33702cd8035d1d2b6aac1d 304 Gene3D G3DSA:3.40.50.300 45 277 1.3E-60 T 31-10-2018 N186_06915 e0327b721f33702cd8035d1d2b6aac1d 304 SUPERFAMILY SSF52540 44 278 1.28E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06915 e0327b721f33702cd8035d1d2b6aac1d 304 Pfam PF06745 KaiC 49 277 3.2E-55 T 31-10-2018 IPR014774 KaiC-like domain N186_02875 d845bd4e827e94510fdbae064f6134db 261 Gene3D G3DSA:3.40.50.300 1 250 2.0E-69 T 31-10-2018 N186_02875 d845bd4e827e94510fdbae064f6134db 261 Pfam PF03029 Conserved hypothetical ATP binding protein 8 247 2.1E-61 T 31-10-2018 IPR004130 GPN-loop GTPase N186_02875 d845bd4e827e94510fdbae064f6134db 261 PRINTS PR00449 Transforming protein P21 ras signature 226 248 3.5E-6 T 31-10-2018 N186_02875 d845bd4e827e94510fdbae064f6134db 261 PRINTS PR00449 Transforming protein P21 ras signature 4 25 3.5E-6 T 31-10-2018 N186_02875 d845bd4e827e94510fdbae064f6134db 261 PRINTS PR00449 Transforming protein P21 ras signature 163 176 3.5E-6 T 31-10-2018 N186_02875 d845bd4e827e94510fdbae064f6134db 261 SUPERFAMILY SSF52540 6 247 3.96E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02785 38201f7f649976d5d2d7e21ff9522b99 208 Gene3D G3DSA:2.40.50.140 16 71 6.7E-6 T 31-10-2018 N186_02785 38201f7f649976d5d2d7e21ff9522b99 208 Pfam PF04919 Protein of unknown function (DUF655) 15 189 2.2E-53 T 31-10-2018 IPR007003 Protein of unknown function DUF655 N186_02785 38201f7f649976d5d2d7e21ff9522b99 208 SUPERFAMILY SSF160975 16 189 9.94E-59 T 31-10-2018 N186_02785 38201f7f649976d5d2d7e21ff9522b99 208 Gene3D G3DSA:1.10.150.280 86 181 1.5E-36 T 31-10-2018 N186_09400 6c45a285491ccd2babade74a27795187 524 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_09400 6c45a285491ccd2babade74a27795187 524 ProSitePatterns PS00211 ABC transporters family signature. 417 431 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_09400 6c45a285491ccd2babade74a27795187 524 SUPERFAMILY SSF52540 271 503 1.0E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09400 6c45a285491ccd2babade74a27795187 524 SMART SM00382 35 229 5.9E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_09400 6c45a285491ccd2babade74a27795187 524 Pfam PF00005 ABC transporter 289 440 4.7E-12 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09400 6c45a285491ccd2babade74a27795187 524 Gene3D G3DSA:3.40.50.300 3 254 3.8E-59 T 31-10-2018 N186_09400 6c45a285491ccd2babade74a27795187 524 Gene3D G3DSA:3.40.50.300 267 509 1.6E-39 T 31-10-2018 N186_09400 6c45a285491ccd2babade74a27795187 524 SUPERFAMILY SSF52540 8 237 6.63E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09400 6c45a285491ccd2babade74a27795187 524 Pfam PF00005 ABC transporter 26 180 1.3E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_07345 77a8c63dc9575ddf82867779742920dd 234 Gene3D G3DSA:1.10.150.400 14 94 9.6E-44 T 31-10-2018 N186_07345 77a8c63dc9575ddf82867779742920dd 234 SUPERFAMILY SSF56784 2 230 1.21E-30 T 31-10-2018 IPR036412 HAD-like superfamily N186_07345 77a8c63dc9575ddf82867779742920dd 234 Gene3D G3DSA:3.40.50.1000 3 207 9.6E-44 T 31-10-2018 IPR023214 HAD superfamily N186_07345 77a8c63dc9575ddf82867779742920dd 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 98 197 6.0E-12 T 31-10-2018 N186_07345 77a8c63dc9575ddf82867779742920dd 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 2.5E-5 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_07345 77a8c63dc9575ddf82867779742920dd 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 2.5E-5 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_07345 77a8c63dc9575ddf82867779742920dd 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 2.5E-5 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_00635 b27321bc194f2b7abefc135d93802956 616 Gene3D G3DSA:1.10.275.40 220 344 5.8E-76 T 31-10-2018 N186_00635 b27321bc194f2b7abefc135d93802956 616 Gene3D G3DSA:1.10.30.20 95 165 5.8E-76 T 31-10-2018 N186_00635 b27321bc194f2b7abefc135d93802956 616 Gene3D G3DSA:3.40.50.300 26 377 5.8E-76 T 31-10-2018 N186_00635 b27321bc194f2b7abefc135d93802956 616 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 202 211 - T 31-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site N186_00635 b27321bc194f2b7abefc135d93802956 616 SMART SM00488 4 256 2.3E-11 T 31-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 N186_00635 b27321bc194f2b7abefc135d93802956 616 SUPERFAMILY SSF52540 27 570 2.47E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00635 b27321bc194f2b7abefc135d93802956 616 SMART SM00491 440 583 3.6E-25 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 N186_00635 b27321bc194f2b7abefc135d93802956 616 Pfam PF06733 DEAD_2 63 214 4.9E-23 T 31-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 N186_00635 b27321bc194f2b7abefc135d93802956 616 Pfam PF13307 Helicase C-terminal domain 424 583 3.8E-32 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 N186_00635 b27321bc194f2b7abefc135d93802956 616 Gene3D G3DSA:3.40.50.300 392 606 3.5E-44 T 31-10-2018 N186_00635 b27321bc194f2b7abefc135d93802956 616 Pfam PF06777 Helical and beta-bridge domain 279 409 2.0E-11 T 31-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 N186_00765 8232bb4877321994419f28afd8458707 429 SUPERFAMILY SSF103473 5 419 1.31E-23 T 31-10-2018 IPR036259 MFS transporter superfamily N186_00765 8232bb4877321994419f28afd8458707 429 Gene3D G3DSA:1.20.1250.20 3 420 1.2E-16 T 31-10-2018 N186_00765 8232bb4877321994419f28afd8458707 429 Pfam PF13347 MFS/sugar transport protein 10 388 1.1E-35 T 31-10-2018 N186_04625 127783924007b5e7396be51a0cb9ea99 380 Gene3D G3DSA:3.40.50.10490 35 187 5.0E-34 T 31-10-2018 N186_04625 127783924007b5e7396be51a0cb9ea99 380 SUPERFAMILY SSF53697 71 357 8.25E-45 T 31-10-2018 N186_04625 127783924007b5e7396be51a0cb9ea99 380 Gene3D G3DSA:3.40.50.10490 213 365 2.7E-26 T 31-10-2018 N186_04625 127783924007b5e7396be51a0cb9ea99 380 TIGRFAM TIGR02128 G6PI_arch: bifunctional phosphoglucose/phosphomannose isomerase 56 364 4.5E-71 T 31-10-2018 IPR011857 Bifunctional phosphoglucose/phosphomannose isomerase GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 N186_04625 127783924007b5e7396be51a0cb9ea99 380 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 215 364 6.2E-33 T 31-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 N186_05180 0890f0c4f84899fde52bd814e3898338 239 Gene3D G3DSA:1.10.1760.20 4 157 1.1E-5 T 31-10-2018 N186_07275 8ba9df4c850a6193b6322c8d73cf00be 324 Gene3D G3DSA:3.40.50.300 6 242 2.8E-57 T 31-10-2018 N186_07275 8ba9df4c850a6193b6322c8d73cf00be 324 Pfam PF13732 Domain of unknown function (DUF4162) 224 309 5.4E-8 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 N186_07275 8ba9df4c850a6193b6322c8d73cf00be 324 Pfam PF00005 ABC transporter 28 171 1.2E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_07275 8ba9df4c850a6193b6322c8d73cf00be 324 SMART SM00382 36 218 2.8E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_07275 8ba9df4c850a6193b6322c8d73cf00be 324 SUPERFAMILY SSF52540 10 230 8.4E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 Gene3D G3DSA:3.90.1820.10 1 456 4.0E-153 T 31-10-2018 N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 SUPERFAMILY SSF51735 3 172 4.2E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 SUPERFAMILY SSF56327 173 455 5.61E-72 T 31-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 PRINTS PR00732 Glycosyl hydrolase family 4 signature 169 180 1.4E-12 T 31-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 1.4E-12 T 31-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 PRINTS PR00732 Glycosyl hydrolase family 4 signature 194 206 1.4E-12 T 31-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 PRINTS PR00732 Glycosyl hydrolase family 4 signature 144 161 1.4E-12 T 31-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 1.4E-12 T 31-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 199 429 3.0E-38 T 31-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 Pfam PF02056 Family 4 glycosyl hydrolase 5 184 2.6E-46 T 31-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 N186_08855 c06db8a2fd2a4ed4c1d88ebd5df858ea 456 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 144 174 - T 31-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 N186_03355 ef5ab4205cfa80594ecadc32212207cf 317 SUPERFAMILY SSF56042 145 297 5.02E-24 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily N186_03355 ef5ab4205cfa80594ecadc32212207cf 317 SUPERFAMILY SSF55326 25 138 5.41E-22 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily N186_03355 ef5ab4205cfa80594ecadc32212207cf 317 Gene3D G3DSA:3.30.1330.10 1 144 8.4E-22 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily N186_03355 ef5ab4205cfa80594ecadc32212207cf 317 Pfam PF00586 AIR synthase related protein, N-terminal domain 28 137 8.7E-12 T 31-10-2018 IPR016188 PurM-like, N-terminal domain N186_03355 ef5ab4205cfa80594ecadc32212207cf 317 Gene3D G3DSA:3.90.650.10 146 309 2.0E-28 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily N186_03355 ef5ab4205cfa80594ecadc32212207cf 317 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 9 310 20.679 T 31-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 N186_03625 8579dd8c5199cf99cfbad532c950088d 325 Gene3D G3DSA:1.20.120.920 83 325 1.9E-54 T 31-10-2018 N186_03625 8579dd8c5199cf99cfbad532c950088d 325 Pfam PF01867 CRISPR associated protein Cas1 4 253 4.8E-65 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 N186_03625 8579dd8c5199cf99cfbad532c950088d 325 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 309 23.881 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 N186_03625 8579dd8c5199cf99cfbad532c950088d 325 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 3 315 1.1E-74 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 N186_03625 8579dd8c5199cf99cfbad532c950088d 325 Gene3D G3DSA:3.100.10.20 2 81 6.9E-20 T 31-10-2018 N186_04585 9a7e1dff05975cd627bbd7a27480a773 606 Gene3D G3DSA:3.40.50.300 239 410 6.6E-35 T 31-10-2018 N186_04585 9a7e1dff05975cd627bbd7a27480a773 606 Gene3D G3DSA:3.40.50.300 411 599 1.4E-31 T 31-10-2018 N186_04585 9a7e1dff05975cd627bbd7a27480a773 606 Pfam PF00271 Helicase conserved C-terminal domain 434 539 4.4E-21 T 31-10-2018 IPR001650 Helicase, C-terminal N186_04585 9a7e1dff05975cd627bbd7a27480a773 606 SMART SM00490 462 543 3.1E-14 T 31-10-2018 IPR001650 Helicase, C-terminal N186_04585 9a7e1dff05975cd627bbd7a27480a773 606 SUPERFAMILY SSF52540 290 554 9.63E-43 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04585 9a7e1dff05975cd627bbd7a27480a773 606 Pfam PF04851 Type III restriction enzyme, res subunit 247 388 5.1E-16 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 N186_04585 9a7e1dff05975cd627bbd7a27480a773 606 SMART SM00487 245 418 1.7E-17 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain N186_01385 d5efb332b431963b20d4766416ccecdd 511 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 3.4E-13 T 31-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 Gene3D G3DSA:2.40.40.20 1 83 8.4E-6 T 31-10-2018 N186_01385 d5efb332b431963b20d4766416ccecdd 511 Pfam PF00591 Glycosyl transferase family, a/b domain 158 380 8.1E-12 T 31-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 Gene3D G3DSA:3.40.1030.10 152 406 1.9E-89 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 PIRSF PIRSF000478 21 86 15.0 T 31-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 PIRSF PIRSF000478 84 500 7.4E-122 T 31-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 SUPERFAMILY SSF52418 156 399 3.53E-63 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 Gene3D G3DSA:3.90.1170.30 407 486 2.7E-21 T 31-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 SUPERFAMILY SSF54680 406 499 3.4E-17 T 31-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 SMART SM00941 418 485 1.6E-21 T 31-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 Gene3D G3DSA:1.20.970.10 85 151 8.7E-20 T 31-10-2018 N186_01385 d5efb332b431963b20d4766416ccecdd 511 Hamap MF_02132 AMP phosphorylase. 1 497 42.63 T 31-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 N186_01385 d5efb332b431963b20d4766416ccecdd 511 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 498 6.0E-181 T 31-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 N186_01385 d5efb332b431963b20d4766416ccecdd 511 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 418 484 2.5E-14 T 31-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 31-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01385 d5efb332b431963b20d4766416ccecdd 511 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 3 485 7.3E-173 T 31-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 N186_01385 d5efb332b431963b20d4766416ccecdd 511 SUPERFAMILY SSF47648 87 153 3.92E-15 T 31-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 N186_01515 f0df487dfd7df651610de9b98c890139 503 SUPERFAMILY SSF52440 7 119 9.35E-48 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily N186_01515 f0df487dfd7df651610de9b98c890139 503 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 122 329 1.3E-67 T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 N186_01515 f0df487dfd7df651610de9b98c890139 503 Gene3D G3DSA:3.30.470.130 3 455 7.5E-177 T 31-10-2018 N186_01515 f0df487dfd7df651610de9b98c890139 503 SUPERFAMILY SSF51246 338 450 1.2E-37 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 N186_01515 f0df487dfd7df651610de9b98c890139 503 Pfam PF02785 Biotin carboxylase C-terminal domain 343 449 1.5E-34 T 31-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 N186_01515 f0df487dfd7df651610de9b98c890139 503 SMART SM00878 343 449 3.0E-51 T 31-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 N186_01515 f0df487dfd7df651610de9b98c890139 503 Pfam PF00289 Biotin carboxylase, N-terminal domain 9 117 2.9E-44 T 31-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 N186_01515 f0df487dfd7df651610de9b98c890139 503 SUPERFAMILY SSF56059 103 355 4.55E-63 T 31-10-2018 N186_01515 f0df487dfd7df651610de9b98c890139 503 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 159 173 - T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 N186_01275 3ef20532d9c6d233008943e053775317 356 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 22 88 1.4E-15 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal N186_01275 3ef20532d9c6d233008943e053775317 356 SUPERFAMILY SSF46785 17 106 1.58E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_01275 3ef20532d9c6d233008943e053775317 356 Pfam PF11495 Archaeal transcriptional regulator TrmB 124 352 1.7E-55 T 31-10-2018 IPR021586 Transcription regulator TrmB, C-terminal N186_01275 3ef20532d9c6d233008943e053775317 356 SUPERFAMILY SSF159071 262 351 4.58E-19 T 31-10-2018 N186_01275 3ef20532d9c6d233008943e053775317 356 Gene3D G3DSA:1.10.10.10 16 113 6.3E-19 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 21 233 40.316 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 Pfam PF01269 Fibrillarin 7 231 4.6E-98 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 SUPERFAMILY SSF53335 8 230 3.94E-45 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 SMART SM01206 7 233 1.2E-136 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 PIRSF PIRSF006540 2 233 2.7E-92 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 Gene3D G3DSA:3.30.200.20 2 55 2.5E-17 T 31-10-2018 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 PRINTS PR00052 Fibrillarin signature 129 158 6.2E-58 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 PRINTS PR00052 Fibrillarin signature 159 188 6.2E-58 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 PRINTS PR00052 Fibrillarin signature 211 232 6.2E-58 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 PRINTS PR00052 Fibrillarin signature 78 99 6.2E-58 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 PRINTS PR00052 Fibrillarin signature 28 47 6.2E-58 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 PRINTS PR00052 Fibrillarin signature 51 70 6.2E-58 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 N186_02905 6f728dff7cb9503ac7f937a41b6264d4 233 Gene3D G3DSA:3.40.50.150 56 233 3.0E-67 T 31-10-2018 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 SUPERFAMILY SSF55979 1 124 3.14E-33 T 31-10-2018 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 231 246 1.7E-12 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 33 51 1.7E-12 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 9 28 1.7E-12 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 55 79 1.7E-12 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 SUPERFAMILY SSF55979 123 245 1.96E-24 T 31-10-2018 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 123 243 5.8E-8 T 31-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 Gene3D G3DSA:3.70.10.10 1 240 4.6E-76 T 31-10-2018 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 7 246 5.0E-32 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 11 90 4.3E-13 T 31-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 N186_04475 3d8dbed3bb0efe618291fc0ac80debce 246 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 1 245 30.481 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 N186_03230 cab923072c5857958a17ed0f72088640 1279 Pfam PF00270 DEAD/DEAH box helicase 115 244 7.6E-12 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 N186_03230 cab923072c5857958a17ed0f72088640 1279 SUPERFAMILY SSF52540 342 636 4.7E-31 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03230 cab923072c5857958a17ed0f72088640 1279 SMART SM00437 968 1220 4.0E-93 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 Hamap MF_01125 Reverse gyrase [rgy]. 5 1268 59.338 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 SUPERFAMILY SSF52540 84 263 3.95E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03230 cab923072c5857958a17ed0f72088640 1279 Gene3D G3DSA:1.10.290.10 978 1102 1.0E-134 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 N186_03230 cab923072c5857958a17ed0f72088640 1279 Gene3D G3DSA:3.40.50.140 772 865 1.7E-23 T 31-10-2018 N186_03230 cab923072c5857958a17ed0f72088640 1279 Gene3D G3DSA:3.40.50.300 85 335 4.9E-84 T 31-10-2018 N186_03230 cab923072c5857958a17ed0f72088640 1279 Gene3D G3DSA:2.60.510.20 917 1166 1.0E-134 T 31-10-2018 N186_03230 cab923072c5857958a17ed0f72088640 1279 Gene3D G3DSA:3.40.50.300 561 646 7.4E-14 T 31-10-2018 N186_03230 cab923072c5857958a17ed0f72088640 1279 Gene3D G3DSA:3.40.50.300 339 520 4.2E-28 T 31-10-2018 N186_03230 cab923072c5857958a17ed0f72088640 1279 SMART SM00493 658 835 6.7E-22 T 31-10-2018 IPR006171 TOPRIM domain N186_03230 cab923072c5857958a17ed0f72088640 1279 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 809 822 1.2E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1091 1107 1.2E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1010 1019 1.2E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 895 913 1.2E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1182 1196 1.2E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 SUPERFAMILY SSF56712 654 1266 1.83E-136 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain N186_03230 cab923072c5857958a17ed0f72088640 1279 Gene3D G3DSA:2.20.20.30 696 761 1.7E-7 T 31-10-2018 N186_03230 cab923072c5857958a17ed0f72088640 1279 SMART SM00436 836 925 6.3E-39 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 Pfam PF01751 Toprim domain 660 845 4.7E-24 T 31-10-2018 IPR006171 TOPRIM domain N186_03230 cab923072c5857958a17ed0f72088640 1279 Pfam PF01131 DNA topoisomerase 859 1257 1.1E-85 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 SMART SM00487 102 351 1.2E-22 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain N186_03230 cab923072c5857958a17ed0f72088640 1279 TIGRFAM TIGR01054 rgy: reverse gyrase 8 1266 0.0 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 N186_03230 cab923072c5857958a17ed0f72088640 1279 Gene3D G3DSA:1.10.460.10 866 1261 1.0E-134 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 N186_07475 387bfc887c0ae4cfc23619760da4f9a8 95 Pfam PF02915 Rubrerythrin 25 90 1.4E-9 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 N186_07475 387bfc887c0ae4cfc23619760da4f9a8 95 Gene3D G3DSA:1.20.1260.10 7 95 2.4E-9 T 31-10-2018 IPR012347 Ferritin-like N186_07475 387bfc887c0ae4cfc23619760da4f9a8 95 SUPERFAMILY SSF47240 6 84 3.11E-20 T 31-10-2018 IPR009078 Ferritin-like superfamily N186_05365 e5f1c17aa1b4de625364917888c4379e 281 SMART SM00418 14 87 0.0065 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_05365 e5f1c17aa1b4de625364917888c4379e 281 Gene3D G3DSA:1.10.10.10 2 83 1.9E-12 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_05365 e5f1c17aa1b4de625364917888c4379e 281 SUPERFAMILY SSF46785 13 91 4.27E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_05365 e5f1c17aa1b4de625364917888c4379e 281 Pfam PF12840 Helix-turn-helix domain 15 67 6.5E-8 T 31-10-2018 N186_07130 7bcec5a40948ae41aa41db590c45eb2f 452 Gene3D G3DSA:1.20.1740.10 6 450 2.8E-77 T 31-10-2018 N186_07130 7bcec5a40948ae41aa41db590c45eb2f 452 PIRSF PIRSF006060 1 451 2.5E-69 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 N186_07130 7bcec5a40948ae41aa41db590c45eb2f 452 Pfam PF13520 Amino acid permease 18 419 2.2E-48 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 N186_08655 3b79d994844b833ed6115f7fbc70e6ee 394 SMART SM00933 33 358 5.7E-16 T 31-10-2018 IPR018977 NurA domain N186_08655 3b79d994844b833ed6115f7fbc70e6ee 394 Pfam PF09376 NurA domain 38 357 4.1E-18 T 31-10-2018 IPR018977 NurA domain N186_02795 3bad45716f73b5a0d92a6669c6281a0b 102 SUPERFAMILY SSF50104 3 95 6.32E-27 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily N186_02795 3bad45716f73b5a0d92a6669c6281a0b 102 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 2 96 24.692 T 31-10-2018 IPR022856 Ribosomal protein L21e, archaeal N186_02795 3bad45716f73b5a0d92a6669c6281a0b 102 Pfam PF01157 Ribosomal protein L21e 3 94 1.4E-26 T 31-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02795 3bad45716f73b5a0d92a6669c6281a0b 102 Gene3D G3DSA:2.30.30.70 1 95 5.8E-31 T 31-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03530 8d236b90a143e5ee5fb4a673a6ca2caa 467 Gene3D G3DSA:3.90.1640.30 4 210 1.7E-11 T 31-10-2018 N186_03530 8d236b90a143e5ee5fb4a673a6ca2caa 467 Pfam PF02272 DHHA1 domain 348 465 8.1E-11 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 N186_03530 8d236b90a143e5ee5fb4a673a6ca2caa 467 SUPERFAMILY SSF64182 15 466 2.79E-48 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 SUPERFAMILY SSF56300 24 291 1.67E-70 T 31-10-2018 N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 PRINTS PR00114 Serine/threonine phosphatase family signature 117 141 3.1E-30 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 PRINTS PR00114 Serine/threonine phosphatase family signature 241 261 3.1E-30 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 PRINTS PR00114 Serine/threonine phosphatase family signature 84 111 3.1E-30 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 PRINTS PR00114 Serine/threonine phosphatase family signature 151 177 3.1E-30 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 PRINTS PR00114 Serine/threonine phosphatase family signature 183 210 3.1E-30 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 Pfam PF00149 Calcineurin-like phosphoesterase 55 252 2.3E-24 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 Gene3D G3DSA:3.60.21.10 2 291 3.6E-74 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 118 123 - T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 N186_02680 8ae47a3922703eaa7faea9cc35e98122 292 SMART SM00156 26 292 3.7E-60 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 N186_01935 24ce1af01ade6dc9666403e6471ca752 370 SUPERFAMILY SSF55205 21 237 2.09E-56 T 31-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 N186_01935 24ce1af01ade6dc9666403e6471ca752 370 Gene3D G3DSA:3.30.360.20 201 299 4.3E-112 T 31-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily N186_01935 24ce1af01ade6dc9666403e6471ca752 370 Gene3D G3DSA:3.65.10.20 23 345 4.3E-112 T 31-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily N186_01935 24ce1af01ade6dc9666403e6471ca752 370 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 206 297 7.8E-19 T 31-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain N186_01935 24ce1af01ade6dc9666403e6471ca752 370 SUPERFAMILY SSF52913 210 300 1.44E-18 T 31-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily N186_01935 24ce1af01ade6dc9666403e6471ca752 370 PIRSF PIRSF005378 19 366 5.8E-107 T 31-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 N186_01935 24ce1af01ade6dc9666403e6471ca752 370 Pfam PF01137 RNA 3'-terminal phosphate cyclase 29 349 2.9E-76 T 31-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain N186_01935 24ce1af01ade6dc9666403e6471ca752 370 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 22 347 1.3E-115 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 N186_01935 24ce1af01ade6dc9666403e6471ca752 370 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 21 363 37.897 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 N186_02605 d1fcb067c74312b711200a0e153dc17c 414 Gene3D G3DSA:3.50.30.30 61 184 4.3E-64 T 31-10-2018 N186_02605 d1fcb067c74312b711200a0e153dc17c 414 SUPERFAMILY SSF53187 3 387 3.24E-54 T 31-10-2018 N186_02605 d1fcb067c74312b711200a0e153dc17c 414 Gene3D G3DSA:3.40.630.10 20 367 4.3E-64 T 31-10-2018 N186_02605 d1fcb067c74312b711200a0e153dc17c 414 Pfam PF04389 Peptidase family M28 194 375 1.4E-35 T 31-10-2018 IPR007484 Peptidase M28 N186_07155 ecf6299234475fc86e8bc2f123631acf 404 Gene3D G3DSA:3.40.50.720 5 379 5.0E-48 T 31-10-2018 N186_07155 ecf6299234475fc86e8bc2f123631acf 404 SUPERFAMILY SSF51735 1 157 2.42E-13 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_07155 ecf6299234475fc86e8bc2f123631acf 404 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 127 2.1E-8 T 31-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 N186_07155 ecf6299234475fc86e8bc2f123631acf 404 Gene3D G3DSA:3.30.360.10 141 343 5.0E-48 T 31-10-2018 N186_03340 083ff4a386e1c64d52d7ed78f402c37d 102 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 7 92 18.785 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03340 083ff4a386e1c64d52d7ed78f402c37d 102 Pfam PF01198 Ribosomal protein L31e 11 85 6.1E-14 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03340 083ff4a386e1c64d52d7ed78f402c37d 102 ProSitePatterns PS01144 Ribosomal protein L31e signature. 51 65 - T 31-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03340 083ff4a386e1c64d52d7ed78f402c37d 102 Gene3D G3DSA:3.10.440.10 7 91 9.8E-25 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03340 083ff4a386e1c64d52d7ed78f402c37d 102 SMART SM01380 7 88 4.0E-22 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03340 083ff4a386e1c64d52d7ed78f402c37d 102 SUPERFAMILY SSF54575 10 82 4.18E-19 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03340 083ff4a386e1c64d52d7ed78f402c37d 102 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 11 58 3.0E-5 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05155 f510be2f9272151b43733695ff31ffe7 157 SMART SM00470 9 91 1.6E-7 T 31-10-2018 IPR003115 ParB/Sulfiredoxin N186_05155 f510be2f9272151b43733695ff31ffe7 157 Pfam PF02195 ParB-like nuclease domain 27 77 8.1E-10 T 31-10-2018 IPR003115 ParB/Sulfiredoxin N186_05155 f510be2f9272151b43733695ff31ffe7 157 SUPERFAMILY SSF110849 8 118 9.03E-28 T 31-10-2018 IPR036086 ParB/Sulfiredoxin superfamily N186_05155 f510be2f9272151b43733695ff31ffe7 157 Gene3D G3DSA:3.90.1530.10 2 98 3.6E-23 T 31-10-2018 N186_09390 973bdc6cc0b9ab59a3b885390af2f6bf 185 SUPERFAMILY SSF52540 2 136 8.5E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09390 973bdc6cc0b9ab59a3b885390af2f6bf 185 SUPERFAMILY SSF57716 137 184 2.78E-16 T 31-10-2018 N186_09390 973bdc6cc0b9ab59a3b885390af2f6bf 185 Gene3D G3DSA:3.40.50.300 2 136 2.1E-42 T 31-10-2018 N186_09390 973bdc6cc0b9ab59a3b885390af2f6bf 185 PIRSF PIRSF035805 1 185 2.9E-63 T 31-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 N186_09390 973bdc6cc0b9ab59a3b885390af2f6bf 185 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 169 182 - T 31-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 N186_09390 973bdc6cc0b9ab59a3b885390af2f6bf 185 Pfam PF00265 Thymidine kinase 3 182 2.2E-50 T 31-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 N186_09390 973bdc6cc0b9ab59a3b885390af2f6bf 185 Hamap MF_00124 Thymidine kinase [tdk]. 2 185 32.523 T 31-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 N186_09390 973bdc6cc0b9ab59a3b885390af2f6bf 185 Gene3D G3DSA:3.30.60.20 137 185 1.0E-24 T 31-10-2018 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 8.4E-58 T 31-10-2018 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 PRINTS PR01469 Bacterial carbamate kinase signature 176 194 8.4E-58 T 31-10-2018 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 PRINTS PR01469 Bacterial carbamate kinase signature 153 172 8.4E-58 T 31-10-2018 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 PRINTS PR01469 Bacterial carbamate kinase signature 74 92 8.4E-58 T 31-10-2018 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 PRINTS PR01469 Bacterial carbamate kinase signature 206 221 8.4E-58 T 31-10-2018 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 PRINTS PR01469 Bacterial carbamate kinase signature 261 276 8.4E-58 T 31-10-2018 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 PRINTS PR01469 Bacterial carbamate kinase signature 105 124 8.4E-58 T 31-10-2018 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 Pfam PF00696 Amino acid kinase family 5 283 8.0E-27 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 ProSitePatterns PS01128 Shikimate kinase signature. 164 189 - T 31-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 TIGRFAM TIGR00746 arcC: carbamate kinase 6 305 3.4E-109 T 31-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 PIRSF PIRSF000723 2 306 2.2E-113 T 31-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 Gene3D G3DSA:3.40.1160.10 1 306 3.0E-112 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily N186_01790 d7f1674325a4d4f2f49f6fe18e905bce 308 SUPERFAMILY SSF53633 4 304 3.8E-75 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily N186_08030 8ad512967f8515e7fb9a953a63d4227f 361 Gene3D G3DSA:3.40.50.2000 3 185 7.1E-110 T 31-10-2018 N186_08030 8ad512967f8515e7fb9a953a63d4227f 361 SUPERFAMILY SSF53756 1 356 1.67E-102 T 31-10-2018 N186_08030 8ad512967f8515e7fb9a953a63d4227f 361 Gene3D G3DSA:3.40.50.2000 186 318 7.1E-110 T 31-10-2018 N186_08030 8ad512967f8515e7fb9a953a63d4227f 361 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 352 3.8E-98 T 31-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 N186_08030 8ad512967f8515e7fb9a953a63d4227f 361 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 328 3.5E-84 T 31-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 N186_08540 fc1d13b922371e42811ee290949e6e9e 247 SMART SM00382 33 230 7.2E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_08540 fc1d13b922371e42811ee290949e6e9e 247 SUPERFAMILY SSF52540 4 232 8.96E-74 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08540 fc1d13b922371e42811ee290949e6e9e 247 Gene3D G3DSA:3.40.50.300 1 247 1.9E-71 T 31-10-2018 N186_08540 fc1d13b922371e42811ee290949e6e9e 247 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_08540 fc1d13b922371e42811ee290949e6e9e 247 Pfam PF00005 ABC transporter 25 173 8.3E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09635 669a438130aeb7f124c6d1ad0067e082 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 49 314 6.3E-18 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 N186_09635 669a438130aeb7f124c6d1ad0067e082 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site N186_09635 669a438130aeb7f124c6d1ad0067e082 320 SUPERFAMILY SSF52283 44 126 5.32E-19 T 31-10-2018 N186_09635 669a438130aeb7f124c6d1ad0067e082 320 Gene3D G3DSA:3.40.50.720 92 282 4.8E-84 T 31-10-2018 N186_09635 669a438130aeb7f124c6d1ad0067e082 320 Gene3D G3DSA:3.40.50.720 44 312 4.8E-84 T 31-10-2018 N186_09635 669a438130aeb7f124c6d1ad0067e082 320 SUPERFAMILY SSF51735 96 284 1.11E-52 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_09635 669a438130aeb7f124c6d1ad0067e082 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 283 1.1E-54 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 N186_04415 bd858211167c024e40984cf91d89a75d 302 Gene3D G3DSA:3.40.1190.20 1 285 3.4E-63 T 31-10-2018 IPR029056 Ribokinase-like N186_04415 bd858211167c024e40984cf91d89a75d 302 SUPERFAMILY SSF53613 2 287 1.28E-49 T 31-10-2018 IPR029056 Ribokinase-like N186_04415 bd858211167c024e40984cf91d89a75d 302 Pfam PF00294 pfkB family carbohydrate kinase 15 278 4.5E-26 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB N186_06930 2ae9aaf717914a50e233d1f584f04ce2 341 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site N186_06930 2ae9aaf717914a50e233d1f584f04ce2 341 Gene3D G3DSA:3.40.50.720 102 291 9.9E-96 T 31-10-2018 N186_06930 2ae9aaf717914a50e233d1f584f04ce2 341 SUPERFAMILY SSF52283 3 138 1.13E-24 T 31-10-2018 N186_06930 2ae9aaf717914a50e233d1f584f04ce2 341 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 291 3.0E-63 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 N186_06930 2ae9aaf717914a50e233d1f584f04ce2 341 Gene3D G3DSA:3.40.50.720 19 319 9.9E-96 T 31-10-2018 N186_06930 2ae9aaf717914a50e233d1f584f04ce2 341 SUPERFAMILY SSF51735 107 292 5.81E-57 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_06930 2ae9aaf717914a50e233d1f584f04ce2 341 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 152 180 - T 31-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 N186_06930 2ae9aaf717914a50e233d1f584f04ce2 341 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 15 318 5.8E-24 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 N186_05645 200cc3a468335a993c65d60a6a77c2fa 338 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site N186_05645 200cc3a468335a993c65d60a6a77c2fa 338 Gene3D G3DSA:3.40.50.720 100 291 2.5E-131 T 31-10-2018 N186_05645 200cc3a468335a993c65d60a6a77c2fa 338 SUPERFAMILY SSF52283 3 134 1.83E-39 T 31-10-2018 N186_05645 200cc3a468335a993c65d60a6a77c2fa 338 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 323 2.5E-38 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 N186_05645 200cc3a468335a993c65d60a6a77c2fa 338 SUPERFAMILY SSF51735 105 292 4.01E-64 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_05645 200cc3a468335a993c65d60a6a77c2fa 338 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 291 4.5E-67 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 N186_05645 200cc3a468335a993c65d60a6a77c2fa 338 Hamap MF_00776 Glyoxylate reductase [gyaR]. 2 332 60.424 T 31-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 N186_05645 200cc3a468335a993c65d60a6a77c2fa 338 Gene3D G3DSA:3.40.50.720 5 318 2.5E-131 T 31-10-2018 N186_05645 200cc3a468335a993c65d60a6a77c2fa 338 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 201 223 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site N186_08935 d6f59fc8c1ec21e98785ca131fd87378 155 SUPERFAMILY SSF102712 16 145 9.55E-25 T 31-10-2018 N186_08935 d6f59fc8c1ec21e98785ca131fd87378 155 SMART SM00232 17 142 5.5E-12 T 31-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 N186_08935 d6f59fc8c1ec21e98785ca131fd87378 155 Pfam PF14464 Prokaryotic homologs of the JAB domain 23 126 2.8E-19 T 31-10-2018 IPR028090 JAB domain, prokaryotic N186_08935 d6f59fc8c1ec21e98785ca131fd87378 155 Gene3D G3DSA:3.40.140.10 17 154 5.1E-33 T 31-10-2018 N186_05690 86c003ad71275a657fdbfe5ecb44787f 304 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 55 75 0.26 T 31-10-2018 IPR001330 PFTB repeat GO:0003824 N186_05690 86c003ad71275a657fdbfe5ecb44787f 304 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 214 253 0.035 T 31-10-2018 IPR001330 PFTB repeat GO:0003824 N186_05690 86c003ad71275a657fdbfe5ecb44787f 304 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 264 278 3.0 T 31-10-2018 IPR001330 PFTB repeat GO:0003824 N186_05690 86c003ad71275a657fdbfe5ecb44787f 304 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 5 23 0.73 T 31-10-2018 IPR001330 PFTB repeat GO:0003824 N186_05690 86c003ad71275a657fdbfe5ecb44787f 304 Gene3D G3DSA:1.50.10.20 1 113 3.9E-8 T 31-10-2018 N186_05690 86c003ad71275a657fdbfe5ecb44787f 304 Gene3D G3DSA:1.50.10.20 187 304 9.5E-15 T 31-10-2018 N186_05690 86c003ad71275a657fdbfe5ecb44787f 304 PIRSF PIRSF016175 1 304 4.1E-39 T 31-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related N186_05690 86c003ad71275a657fdbfe5ecb44787f 304 SUPERFAMILY SSF48239 4 234 1.23E-23 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid N186_06065 9f1d86256633bf0c68cf543ebb1c49a0 386 Gene3D G3DSA:1.20.1250.20 1 380 5.4E-34 T 31-10-2018 N186_06065 9f1d86256633bf0c68cf543ebb1c49a0 386 SUPERFAMILY SSF103473 3 379 2.62E-37 T 31-10-2018 IPR036259 MFS transporter superfamily N186_06065 9f1d86256633bf0c68cf543ebb1c49a0 386 Pfam PF07690 Major Facilitator Superfamily 3 339 3.0E-20 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_05970 d00351c32dab7e87580c0733b401d29b 695 Pfam PF07664 Ferrous iron transport protein B C terminus 484 536 3.4E-11 T 31-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 N186_05970 d00351c32dab7e87580c0733b401d29b 695 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 11 658 3.2E-146 T 31-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 N186_05970 d00351c32dab7e87580c0733b401d29b 695 Gene3D G3DSA:3.40.50.300 4 171 2.5E-47 T 31-10-2018 N186_05970 d00351c32dab7e87580c0733b401d29b 695 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 55 70 7.6E-7 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_05970 d00351c32dab7e87580c0733b401d29b 695 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 7.6E-7 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_05970 d00351c32dab7e87580c0733b401d29b 695 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 159 7.7E-13 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 N186_05970 d00351c32dab7e87580c0733b401d29b 695 Pfam PF07670 Nucleoside recognition 542 663 1.3E-17 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 N186_05970 d00351c32dab7e87580c0733b401d29b 695 Pfam PF07670 Nucleoside recognition 379 468 3.5E-7 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 N186_05970 d00351c32dab7e87580c0733b401d29b 695 SUPERFAMILY SSF52540 6 168 5.4E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05970 d00351c32dab7e87580c0733b401d29b 695 Pfam PF02421 Ferrous iron transport protein B 6 160 1.2E-56 T 31-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 Pfam PF00271 Helicase conserved C-terminal domain 247 341 7.2E-19 T 31-10-2018 IPR001650 Helicase, C-terminal N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 Pfam PF00270 DEAD/DEAH box helicase 32 198 1.5E-28 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 SUPERFAMILY SSF52540 42 355 3.3E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 SMART SM00382 42 284 0.0038 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 PIRSF PIRSF037307 4 934 1.4E-245 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 Pfam PF08494 DEAD/H associated 593 771 1.1E-10 T 31-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 Gene3D G3DSA:3.40.50.300 11 210 9.2E-46 T 31-10-2018 N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 SMART SM00487 25 229 1.4E-35 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 SMART SM00490 262 341 9.2E-20 T 31-10-2018 IPR001650 Helicase, C-terminal N186_06420 93e5f96a21adf85f7c5f35f6157beca5 935 Gene3D G3DSA:3.40.50.300 221 391 4.4E-28 T 31-10-2018 N186_05825 229ed3a3e043ddaaf0d46cccd0a9c2e2 291 Gene3D G3DSA:3.20.20.150 13 283 6.6E-41 T 31-10-2018 N186_05825 229ed3a3e043ddaaf0d46cccd0a9c2e2 291 SMART SM00518 11 276 2.6E-65 T 31-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 N186_05825 229ed3a3e043ddaaf0d46cccd0a9c2e2 291 SUPERFAMILY SSF51658 7 277 3.59E-55 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily N186_05825 229ed3a3e043ddaaf0d46cccd0a9c2e2 291 Pfam PF01261 Xylose isomerase-like TIM barrel 29 237 4.1E-18 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain N186_06705 3a7d8cd4f0ff97c5b4433395865e831d 533 Pfam PF03609 PTS system sorbose-specific iic component 9 246 1.9E-56 T 31-10-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 N186_06705 3a7d8cd4f0ff97c5b4433395865e831d 533 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 275 532 5.0E-79 T 31-10-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PIRSF PIRSF000350 1 426 2.7E-73 T 31-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 N186_00730 a69753f5010c46c18dafb946192be1e2 469 Gene3D G3DSA:3.50.50.60 145 268 1.6E-85 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_00730 a69753f5010c46c18dafb946192be1e2 469 SUPERFAMILY SSF55424 342 458 3.78E-27 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 N186_00730 a69753f5010c46c18dafb946192be1e2 469 Gene3D G3DSA:1.10.287.990 37 106 1.6E-85 T 31-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 N186_00730 a69753f5010c46c18dafb946192be1e2 469 Gene3D G3DSA:3.30.390.30 343 460 1.8E-30 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 1.5E-48 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 1.5E-48 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 1.5E-48 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 1.5E-48 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.5E-48 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 1.5E-48 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.5E-48 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 1.5E-48 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 1.5E-48 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 2.2E-19 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 2.2E-19 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 2.2E-19 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 2.2E-19 T 31-10-2018 N186_00730 a69753f5010c46c18dafb946192be1e2 469 SUPERFAMILY SSF51905 1 365 2.19E-40 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_00730 a69753f5010c46c18dafb946192be1e2 469 Gene3D G3DSA:3.50.50.60 6 327 1.6E-85 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_00730 a69753f5010c46c18dafb946192be1e2 469 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 315 6.9E-48 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 N186_00730 a69753f5010c46c18dafb946192be1e2 469 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 453 1.0E-23 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 N186_00730 a69753f5010c46c18dafb946192be1e2 469 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 31-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 N186_07405 2c6a09045ad46711fa00049f6badd5cf 590 Pfam PF01266 FAD dependent oxidoreductase 96 466 2.3E-64 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 N186_07405 2c6a09045ad46711fa00049f6badd5cf 590 SUPERFAMILY SSF54373 329 427 1.69E-5 T 31-10-2018 N186_07405 2c6a09045ad46711fa00049f6badd5cf 590 SUPERFAMILY SSF51905 95 518 2.23E-51 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_07405 2c6a09045ad46711fa00049f6badd5cf 590 Gene3D G3DSA:1.10.10.1100 500 573 2.3E-23 T 31-10-2018 N186_07405 2c6a09045ad46711fa00049f6badd5cf 590 Pfam PF04324 BFD-like [2Fe-2S] binding domain 512 563 1.6E-13 T 31-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain N186_07405 2c6a09045ad46711fa00049f6badd5cf 590 Gene3D G3DSA:3.30.9.10 179 428 2.0E-106 T 31-10-2018 N186_07405 2c6a09045ad46711fa00049f6badd5cf 590 Pfam PF04972 BON domain 6 66 7.5E-7 T 31-10-2018 IPR007055 BON domain N186_07405 2c6a09045ad46711fa00049f6badd5cf 590 Gene3D G3DSA:3.50.50.60 96 462 2.0E-106 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_05235 3a0ed386bfa9d47eff3023ca4715bb62 424 SUPERFAMILY SSF53649 2 393 9.81E-27 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 N186_05235 3a0ed386bfa9d47eff3023ca4715bb62 424 Gene3D G3DSA:3.30.70.2130 75 247 1.5E-100 T 31-10-2018 N186_05235 3a0ed386bfa9d47eff3023ca4715bb62 424 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 5 415 7.5E-101 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_05235 3a0ed386bfa9d47eff3023ca4715bb62 424 Gene3D G3DSA:3.40.720.10 4 408 1.5E-100 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 N186_05235 3a0ed386bfa9d47eff3023ca4715bb62 424 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 34 224 8.3E-51 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_05235 3a0ed386bfa9d47eff3023ca4715bb62 424 Pfam PF01676 Metalloenzyme superfamily 4 405 6.5E-33 T 31-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 N186_05235 3a0ed386bfa9d47eff3023ca4715bb62 424 PIRSF PIRSF006392 1 423 7.3E-116 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_02985 08ddfa93ce8f673bc2d7e67c486f8026 217 Pfam PF01865 Protein of unknown function DUF47 13 215 4.2E-5 T 31-10-2018 IPR018445 Putative phosphate transport regulator N186_02985 08ddfa93ce8f673bc2d7e67c486f8026 217 Gene3D G3DSA:1.20.58.220 3 214 3.2E-19 T 31-10-2018 IPR038078 PhoU-like domain superfamily N186_02100 d384f79721333f89100ece2ed3c26683 196 SUPERFAMILY SSF53137 3 194 1.31E-58 T 31-10-2018 N186_02100 d384f79721333f89100ece2ed3c26683 196 Pfam PF14204 Ribosomal L18 C-terminal region 140 193 3.8E-12 T 31-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02100 d384f79721333f89100ece2ed3c26683 196 Gene3D G3DSA:3.30.420.100 1 196 2.1E-66 T 31-10-2018 N186_02100 d384f79721333f89100ece2ed3c26683 196 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 191 41.297 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02100 d384f79721333f89100ece2ed3c26683 196 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 97 131 4.2E-8 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02100 d384f79721333f89100ece2ed3c26683 196 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 95 9.6E-18 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 SMART SM00279 225 259 2.7E-4 T 31-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 SMART SM00485 1 103 8.8E-46 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 Pfam PF00752 XPG N-terminal domain 6 102 5.0E-24 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 Pfam PF00867 XPG I-region 143 238 2.0E-26 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 SUPERFAMILY SSF88723 6 238 9.48E-63 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 SMART SM00484 142 223 1.5E-31 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 Gene3D G3DSA:3.40.50.1010 3 346 1.4E-99 T 31-10-2018 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 345 135.193 T 31-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 ProSitePatterns PS00841 XPG protein signature 1. 75 89 - T 31-10-2018 IPR019974 XPG conserved site GO:0016788 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 SUPERFAMILY SSF47807 223 345 8.22E-28 T 31-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 2 344 1.5E-148 T 31-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 77 96 2.0E-30 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 141 158 2.0E-30 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 228 243 2.0E-30 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 23 37 2.0E-30 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_02515 48e6cd7bc0bd98de5e4630d8df58be65 346 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 162 182 2.0E-30 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 N186_06350 b85e89f887bd61d60403f3e6363010ec 243 Gene3D G3DSA:1.10.150.520 21 112 1.0E-28 T 31-10-2018 N186_06350 b85e89f887bd61d60403f3e6363010ec 243 SUPERFAMILY SSF56784 8 239 1.23E-30 T 31-10-2018 IPR036412 HAD-like superfamily N186_06350 b85e89f887bd61d60403f3e6363010ec 243 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 110 211 1.1E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_06350 b85e89f887bd61d60403f3e6363010ec 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 84 211 6.1E-17 T 31-10-2018 N186_06350 b85e89f887bd61d60403f3e6363010ec 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 156 172 1.6E-9 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_06350 b85e89f887bd61d60403f3e6363010ec 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 124 137 1.6E-9 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_06350 b85e89f887bd61d60403f3e6363010ec 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 1.6E-9 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_06350 b85e89f887bd61d60403f3e6363010ec 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 201 214 1.6E-9 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_06350 b85e89f887bd61d60403f3e6363010ec 243 Gene3D G3DSA:3.40.50.1000 10 230 1.0E-28 T 31-10-2018 IPR023214 HAD superfamily N186_06350 b85e89f887bd61d60403f3e6363010ec 243 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 117 206 3.6E-8 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_07280 0b705d179b4a8907a7ed8dbf51ea7efa 269 PIRSF PIRSF006648 3 264 1.2E-18 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_05560 3a951d8023d6a50de3efabc6d272fbc0 308 Gene3D G3DSA:3.30.300.110 24 110 1.7E-22 T 31-10-2018 N186_05560 3a951d8023d6a50de3efabc6d272fbc0 308 Pfam PF02475 Met-10+ like-protein 48 254 1.6E-60 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 N186_05560 3a951d8023d6a50de3efabc6d272fbc0 308 Gene3D G3DSA:3.40.50.150 113 308 3.6E-51 T 31-10-2018 N186_05560 3a951d8023d6a50de3efabc6d272fbc0 308 SUPERFAMILY SSF53335 38 307 4.58E-63 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_06550 41867be1416800800c677c30cb6d36d2 140 SUPERFAMILY SSF56770 11 136 1.44E-54 T 31-10-2018 N186_06550 41867be1416800800c677c30cb6d36d2 140 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 108 124 - T 31-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06550 41867be1416800800c677c30cb6d36d2 140 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 136 1.5E-43 T 31-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06550 41867be1416800800c677c30cb6d36d2 140 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 25 136 5.1E-32 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06550 41867be1416800800c677c30cb6d36d2 140 Gene3D G3DSA:3.40.50.12280 5 138 8.1E-55 T 31-10-2018 N186_05905 07fc270d2d08c18b9f70634be615c67d 441 Gene3D G3DSA:1.10.8.60 351 441 4.4E-29 T 31-10-2018 N186_05905 07fc270d2d08c18b9f70634be615c67d 441 SUPERFAMILY SSF50249 117 201 2.91E-20 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_05905 07fc270d2d08c18b9f70634be615c67d 441 Pfam PF06068 TIP49 C-terminus 7 400 4.9E-160 T 31-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 N186_05905 07fc270d2d08c18b9f70634be615c67d 441 Gene3D G3DSA:3.40.50.300 10 346 1.6E-108 T 31-10-2018 N186_05905 07fc270d2d08c18b9f70634be615c67d 441 Gene3D G3DSA:2.40.50.360 111 237 1.6E-108 T 31-10-2018 N186_05905 07fc270d2d08c18b9f70634be615c67d 441 SMART SM00382 54 363 2.8E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_05905 07fc270d2d08c18b9f70634be615c67d 441 SUPERFAMILY SSF52540 29 423 5.73E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04810 90d09efc6e595415b97f88c8c24eac50 609 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 239 413 3.9E-43 T 31-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 N186_04810 90d09efc6e595415b97f88c8c24eac50 609 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 586 597 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_04810 90d09efc6e595415b97f88c8c24eac50 609 SUPERFAMILY SSF52402 211 402 9.92E-50 T 31-10-2018 N186_04810 90d09efc6e595415b97f88c8c24eac50 609 SUPERFAMILY SSF54862 536 599 5.58E-14 T 31-10-2018 N186_04810 90d09efc6e595415b97f88c8c24eac50 609 Pfam PF12838 4Fe-4S dicluster domain 555 598 3.1E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_04810 90d09efc6e595415b97f88c8c24eac50 609 Gene3D G3DSA:3.40.50.620 208 426 2.9E-52 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_04810 90d09efc6e595415b97f88c8c24eac50 609 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 555 566 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_04810 90d09efc6e595415b97f88c8c24eac50 609 Gene3D G3DSA:3.30.70.20 542 606 1.8E-10 T 31-10-2018 N186_03480 0a6884eacd0df1acdf4cd6c47e322917 424 SMART SM01027 231 341 7.9E-29 T 31-10-2018 IPR022712 Beta-Casp domain N186_03480 0a6884eacd0df1acdf4cd6c47e322917 424 Pfam PF16661 Metallo-beta-lactamase superfamily domain 21 177 5.8E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_03480 0a6884eacd0df1acdf4cd6c47e322917 424 Pfam PF10996 Beta-Casp domain 231 340 3.2E-14 T 31-10-2018 IPR022712 Beta-Casp domain N186_03480 0a6884eacd0df1acdf4cd6c47e322917 424 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 355 414 1.1E-14 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain N186_03480 0a6884eacd0df1acdf4cd6c47e322917 424 Gene3D G3DSA:3.40.50.10890 199 368 1.3E-104 T 31-10-2018 N186_03480 0a6884eacd0df1acdf4cd6c47e322917 424 Gene3D G3DSA:3.60.15.10 9 402 1.3E-104 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_03480 0a6884eacd0df1acdf4cd6c47e322917 424 SUPERFAMILY SSF56281 4 422 1.76E-104 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_03480 0a6884eacd0df1acdf4cd6c47e322917 424 SMART SM00849 16 219 1.3E-17 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_03170 7354ebeb03d122998b2fa72cdd7dce4a 84 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 1 57 14.485 T 31-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03170 7354ebeb03d122998b2fa72cdd7dce4a 84 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 16 56 2.0E-7 T 31-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 N186_03170 7354ebeb03d122998b2fa72cdd7dce4a 84 Gene3D G3DSA:3.10.20.10 1 76 1.7E-24 T 31-10-2018 N186_03170 7354ebeb03d122998b2fa72cdd7dce4a 84 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 56 4.0E-9 T 31-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03170 7354ebeb03d122998b2fa72cdd7dce4a 84 SUPERFAMILY SSF160374 1 73 4.05E-20 T 31-10-2018 N186_02850 05e17f72f7dd9f23ea5cbbe0208e1922 154 Gene3D G3DSA:3.30.70.920 82 149 1.3E-10 T 31-10-2018 N186_02850 05e17f72f7dd9f23ea5cbbe0208e1922 154 Pfam PF01037 Lrp/AsnC ligand binding domain 87 152 9.5E-9 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain N186_02850 05e17f72f7dd9f23ea5cbbe0208e1922 154 Gene3D G3DSA:1.10.10.10 9 72 3.3E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_02850 05e17f72f7dd9f23ea5cbbe0208e1922 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 32 61 2.7E-5 T 31-10-2018 N186_02850 05e17f72f7dd9f23ea5cbbe0208e1922 154 SUPERFAMILY SSF54909 84 154 2.41E-9 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel N186_02850 05e17f72f7dd9f23ea5cbbe0208e1922 154 SUPERFAMILY SSF46785 6 73 2.99E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 Gene3D G3DSA:3.40.50.150 156 331 3.1E-32 T 31-10-2018 N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 250 262 2.4E-5 T 31-10-2018 N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 271 295 2.4E-5 T 31-10-2018 N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 200 2.4E-5 T 31-10-2018 N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 SMART SM00981 60 148 7.0E-8 T 31-10-2018 IPR004114 THUMP domain GO:0003723 N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 Pfam PF02926 THUMP domain 39 136 2.7E-11 T 31-10-2018 IPR004114 THUMP domain GO:0003723 N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 SUPERFAMILY SSF53335 141 294 3.5E-23 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 253 259 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 Gene3D G3DSA:3.30.2130.30 1 151 1.2E-19 T 31-10-2018 N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 Pfam PF01170 Putative RNA methylase family UPF0020 157 316 1.2E-23 T 31-10-2018 IPR000241 Putative RNA methylase domain N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 188 199 - T 31-10-2018 IPR000241 Putative RNA methylase domain N186_04280 62cd8b008be22d23b62d6581f32e78e7 332 SUPERFAMILY SSF143437 32 141 2.62E-14 T 31-10-2018 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 PIRSF PIRSF500175 20 447 3.3E-163 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 PIRSF PIRSF001220 97 438 3.1E-102 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 SUPERFAMILY SSF141300 7 77 9.02E-18 T 31-10-2018 IPR037222 GatD, N-terminal N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 PRINTS PR00139 Asparaginase/glutaminase family signature 180 198 4.0E-15 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 PRINTS PR00139 Asparaginase/glutaminase family signature 364 382 4.0E-15 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 PRINTS PR00139 Asparaginase/glutaminase family signature 102 113 4.0E-15 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 Gene3D G3DSA:2.30.30.520 5 89 8.0E-19 T 31-10-2018 IPR037222 GatD, N-terminal N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 Gene3D G3DSA:3.40.50.40 313 449 9.6E-48 T 31-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 102 437 6.3E-120 T 31-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 181 191 - T 31-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 36 442 8.1E-167 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 26 443 45.682 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 SUPERFAMILY SSF53774 99 445 9.29E-105 T 31-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 Gene3D G3DSA:3.40.50.1170 93 310 1.1E-67 T 31-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 SMART SM00870 101 427 2.3E-134 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 N186_02825 e11d9c1bd0859f97c5fbe28a7337a797 453 Pfam PF00710 Asparaginase, N-terminal 101 289 1.9E-58 T 31-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 N186_00650 b28096f36085eae25106bc83e329efc3 375 Gene3D G3DSA:3.10.580.10 126 254 1.8E-10 T 31-10-2018 N186_00650 b28096f36085eae25106bc83e329efc3 375 Pfam PF00571 CBS domain 135 180 5.2E-7 T 31-10-2018 IPR000644 CBS domain N186_00650 b28096f36085eae25106bc83e329efc3 375 Pfam PF00571 CBS domain 73 118 5.7E-4 T 31-10-2018 IPR000644 CBS domain N186_00650 b28096f36085eae25106bc83e329efc3 375 Gene3D G3DSA:3.10.580.10 17 125 6.8E-12 T 31-10-2018 N186_00650 b28096f36085eae25106bc83e329efc3 375 SMART SM00116 134 181 0.11 T 31-10-2018 IPR000644 CBS domain N186_00650 b28096f36085eae25106bc83e329efc3 375 SMART SM00116 74 121 17.0 T 31-10-2018 IPR000644 CBS domain N186_00650 b28096f36085eae25106bc83e329efc3 375 SUPERFAMILY SSF54631 65 182 7.09E-19 T 31-10-2018 N186_00650 b28096f36085eae25106bc83e329efc3 375 SUPERFAMILY SSF54631 20 64 3.71E-5 T 31-10-2018 N186_09035 815082405c9c889907d0f2493311e6c7 247 SUPERFAMILY SSF103473 6 241 1.57E-21 T 31-10-2018 IPR036259 MFS transporter superfamily N186_09035 815082405c9c889907d0f2493311e6c7 247 Gene3D G3DSA:1.20.1250.20 4 176 2.8E-19 T 31-10-2018 N186_09035 815082405c9c889907d0f2493311e6c7 247 Pfam PF07690 Major Facilitator Superfamily 7 239 3.3E-16 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_04730 8d0b6c56efde17c976488f39edb9f555 345 Gene3D G3DSA:3.20.20.70 38 224 2.3E-5 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_04730 8d0b6c56efde17c976488f39edb9f555 345 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 322 333 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_04730 8d0b6c56efde17c976488f39edb9f555 345 SUPERFAMILY SSF51395 56 191 1.24E-6 T 31-10-2018 N186_04730 8d0b6c56efde17c976488f39edb9f555 345 SUPERFAMILY SSF54862 275 333 3.43E-6 T 31-10-2018 N186_04730 8d0b6c56efde17c976488f39edb9f555 345 Gene3D G3DSA:3.30.70.20 288 344 2.0E-5 T 31-10-2018 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 550 562 3.0E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 465 478 3.0E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 602 610 3.0E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 Gene3D G3DSA:1.10.132.60 648 773 7.4E-15 T 31-10-2018 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 ProSitePatterns PS00116 DNA polymerase family B signature. 604 612 - T 31-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 Gene3D G3DSA:3.30.420.10 181 376 2.3E-153 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 SMART SM00486 178 616 1.2E-85 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 Pfam PF03104 DNA polymerase family B, exonuclease domain 80 318 1.1E-27 T 31-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 Gene3D G3DSA:3.90.1600.10 454 646 2.3E-60 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 SUPERFAMILY SSF56672 407 827 3.23E-101 T 31-10-2018 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 Gene3D G3DSA:3.30.342.10 3 431 2.3E-153 T 31-10-2018 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 SUPERFAMILY SSF53098 22 402 5.49E-60 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 Gene3D G3DSA:1.10.287.690 512 571 2.3E-60 T 31-10-2018 N186_02430 5e679fc2d3e60155565ee88f09466ea9 837 Pfam PF00136 DNA polymerase family B 393 793 2.5E-51 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_08875 1b41f62cf695fd3d63b6b52d9a2e0cd9 292 Pfam PF13412 Winged helix-turn-helix DNA-binding 184 227 7.6E-9 T 31-10-2018 N186_08875 1b41f62cf695fd3d63b6b52d9a2e0cd9 292 Gene3D G3DSA:1.10.10.10 175 245 3.8E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_08875 1b41f62cf695fd3d63b6b52d9a2e0cd9 292 SMART SM00418 177 253 3.4E-5 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_08875 1b41f62cf695fd3d63b6b52d9a2e0cd9 292 SUPERFAMILY SSF46785 182 251 8.79E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 Gene3D G3DSA:1.10.3370.10 4 476 2.3E-151 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 471 18.547 T 31-10-2018 IPR026593 Protein translocase subunit SecY N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 Pfam PF10559 Plug domain of Sec61p 38 74 2.3E-12 T 31-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 SUPERFAMILY SSF103491 6 461 2.48E-99 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 PIRSF PIRSF004557 4 476 1.5E-94 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 PRINTS PR00303 Preprotein translocase SecY subunit signature 357 379 8.4E-6 T 31-10-2018 N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 PRINTS PR00303 Preprotein translocase SecY subunit signature 440 458 8.4E-6 T 31-10-2018 N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 8.4E-6 T 31-10-2018 N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 28 462 5.5E-79 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 N186_02080 5de2dcaba9b131b7b4782923d42852d5 476 Pfam PF00344 SecY translocase 75 455 1.1E-61 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 N186_01080 bff5510a69bdde302018a853b7756393 273 Gene3D G3DSA:1.10.285.20 45 111 8.7E-6 T 31-10-2018 N186_01080 bff5510a69bdde302018a853b7756393 273 SUPERFAMILY SSF111321 3 259 7.72E-61 T 31-10-2018 IPR036075 AF1104-like superfamily N186_01080 bff5510a69bdde302018a853b7756393 273 PIRSF PIRSF006593 3 263 9.1E-57 T 31-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 N186_01080 bff5510a69bdde302018a853b7756393 273 Pfam PF01937 Protein of unknown function DUF89 35 257 1.1E-39 T 31-10-2018 IPR002791 Domain of unknown function DUF89 N186_01080 bff5510a69bdde302018a853b7756393 273 Gene3D G3DSA:3.40.50.10880 115 262 6.2E-43 T 31-10-2018 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 Gene3D G3DSA:3.40.50.300 1 326 1.6E-80 T 31-10-2018 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 PRINTS PR01868 ABC transporter family E signature 47 71 1.9E-58 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 PRINTS PR01868 ABC transporter family E signature 74 94 1.9E-58 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 PRINTS PR01868 ABC transporter family E signature 102 127 1.9E-58 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 PRINTS PR01868 ABC transporter family E signature 19 34 1.9E-58 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 PRINTS PR01868 ABC transporter family E signature 135 151 1.9E-58 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 PRINTS PR01868 ABC transporter family E signature 151 177 1.9E-58 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 ProSitePatterns PS00211 ABC transporters family signature. 457 471 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 Pfam PF00005 ABC transporter 361 485 2.1E-18 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 50 61 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_01910 67c85c9a90752fe632eb8281346cb88b 603 SUPERFAMILY SSF52540 321 532 2.62E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01910 67c85c9a90752fe632eb8281346cb88b 603 ProSitePatterns PS00211 ABC transporters family signature. 211 225 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 Pfam PF00037 4Fe-4S binding domain 45 66 2.6E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_01910 67c85c9a90752fe632eb8281346cb88b 603 Pfam PF00005 ABC transporter 96 238 9.3E-21 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 SMART SM00382 97 287 2.7E-6 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01910 67c85c9a90752fe632eb8281346cb88b 603 SMART SM00382 364 534 1.6E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01910 67c85c9a90752fe632eb8281346cb88b 603 Gene3D G3DSA:3.40.50.300 333 593 1.0E-50 T 31-10-2018 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 SUPERFAMILY SSF54862 2 93 1.71E-16 T 31-10-2018 N186_01910 67c85c9a90752fe632eb8281346cb88b 603 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 31 1.1E-11 T 31-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain N186_01910 67c85c9a90752fe632eb8281346cb88b 603 SUPERFAMILY SSF52540 76 283 4.55E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08795 1c0320cbb1541e952743d8a370097cb3 363 Pfam PF13439 Glycosyltransferase Family 4 15 170 2.7E-19 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 N186_08795 1c0320cbb1541e952743d8a370097cb3 363 Pfam PF00534 Glycosyl transferases group 1 177 333 1.1E-39 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 N186_08795 1c0320cbb1541e952743d8a370097cb3 363 SUPERFAMILY SSF53756 4 357 1.22E-85 T 31-10-2018 N186_08795 1c0320cbb1541e952743d8a370097cb3 363 Gene3D G3DSA:3.40.50.2000 168 339 2.3E-73 T 31-10-2018 N186_08795 1c0320cbb1541e952743d8a370097cb3 363 Gene3D G3DSA:3.40.50.2000 14 352 2.3E-73 T 31-10-2018 N186_08400 b89ef35359a8a8a88fbc0488c2596ad3 288 SUPERFAMILY SSF158997 242 284 5.1E-6 T 31-10-2018 N186_08400 b89ef35359a8a8a88fbc0488c2596ad3 288 Gene3D G3DSA:2.20.25.10 242 285 2.3E-5 T 31-10-2018 N186_02830 0ed509cdf1af1f5b1bc3b66b2858c855 50 Pfam PF04758 Ribosomal protein S30 4 45 2.6E-10 T 31-10-2018 IPR006846 Ribosomal protein S30 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03445 51f0b45710588f586ebe346577f9998d 82 Gene3D G3DSA:3.30.70.920 8 79 8.5E-26 T 31-10-2018 N186_03445 51f0b45710588f586ebe346577f9998d 82 Pfam PF01037 Lrp/AsnC ligand binding domain 12 82 4.4E-15 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain N186_03445 51f0b45710588f586ebe346577f9998d 82 SUPERFAMILY SSF54909 9 81 2.01E-17 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel N186_06185 428db332706c9451b1c07f1ac6477e03 65 Gene3D G3DSA:3.10.20.30 1 65 8.9E-15 T 31-10-2018 IPR012675 Beta-grasp domain superfamily N186_06185 428db332706c9451b1c07f1ac6477e03 65 SUPERFAMILY SSF54285 5 65 3.05E-11 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp N186_06185 428db332706c9451b1c07f1ac6477e03 65 Pfam PF02597 ThiS family 10 65 1.8E-6 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 N186_04910 55b4678cf065957593fbcc727c71fc59 213 Gene3D G3DSA:1.10.10.10 4 60 5.4E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04910 55b4678cf065957593fbcc727c71fc59 213 Pfam PF08281 Sigma-70, region 4 6 54 2.8E-7 T 31-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 N186_04910 55b4678cf065957593fbcc727c71fc59 213 SUPERFAMILY SSF88659 7 54 2.03E-8 T 31-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like N186_05210 f066c5c835c1b0e5f65a2b632ec3761c 296 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 7 284 1.4E-65 T 31-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 N186_05210 f066c5c835c1b0e5f65a2b632ec3761c 296 SUPERFAMILY SSF161098 22 278 1.44E-21 T 31-10-2018 IPR035906 MetI-like superfamily N186_05210 f066c5c835c1b0e5f65a2b632ec3761c 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 288 1.6E-9 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_05210 f066c5c835c1b0e5f65a2b632ec3761c 296 Gene3D G3DSA:1.10.3720.10 60 290 7.2E-20 T 31-10-2018 IPR035906 MetI-like superfamily N186_04685 5501404e3f8e5c80dd7e6045655575c1 280 Gene3D G3DSA:3.40.1010.10 1 113 8.5E-29 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 N186_04685 5501404e3f8e5c80dd7e6045655575c1 280 Gene3D G3DSA:3.30.950.10 114 266 1.5E-40 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 N186_04685 5501404e3f8e5c80dd7e6045655575c1 280 Hamap MF_01084 Diphthine synthase [dphB]. 1 259 28.804 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 N186_04685 5501404e3f8e5c80dd7e6045655575c1 280 SUPERFAMILY SSF53790 1 263 5.5E-48 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 N186_04685 5501404e3f8e5c80dd7e6045655575c1 280 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 228 3.0E-23 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 N186_04685 5501404e3f8e5c80dd7e6045655575c1 280 PIRSF PIRSF036432 1 260 3.1E-75 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 N186_04685 5501404e3f8e5c80dd7e6045655575c1 280 TIGRFAM TIGR00522 dph5: diphthine synthase 1 255 1.7E-72 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 N186_00360 21bedac4c267d6ef7148b281b4cc5a59 159 SUPERFAMILY SSF88723 12 156 3.08E-14 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_00360 21bedac4c267d6ef7148b281b4cc5a59 159 Gene3D G3DSA:3.40.50.1010 8 158 2.6E-24 T 31-10-2018 N186_04065 8a233bf629b2bbd8a3c94948dbe0dc5f 253 Pfam PF00005 ABC transporter 19 166 9.0E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_04065 8a233bf629b2bbd8a3c94948dbe0dc5f 253 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_04065 8a233bf629b2bbd8a3c94948dbe0dc5f 253 SMART SM00382 28 222 1.3E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04065 8a233bf629b2bbd8a3c94948dbe0dc5f 253 SUPERFAMILY SSF52540 4 229 2.66E-64 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04065 8a233bf629b2bbd8a3c94948dbe0dc5f 253 Gene3D G3DSA:3.40.50.300 1 249 2.8E-66 T 31-10-2018 N186_07020 94864c10efdd27daf121e4bf30c358b7 363 SMART SM00382 28 211 1.2E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_07020 94864c10efdd27daf121e4bf30c358b7 363 SUPERFAMILY SSF50331 237 362 1.14E-23 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal N186_07020 94864c10efdd27daf121e4bf30c358b7 363 Pfam PF00005 ABC transporter 20 161 6.0E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_07020 94864c10efdd27daf121e4bf30c358b7 363 Gene3D G3DSA:2.40.50.100 239 361 7.7E-26 T 31-10-2018 N186_07020 94864c10efdd27daf121e4bf30c358b7 363 Gene3D G3DSA:2.40.50.140 286 347 7.7E-26 T 31-10-2018 N186_07020 94864c10efdd27daf121e4bf30c358b7 363 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_07020 94864c10efdd27daf121e4bf30c358b7 363 SUPERFAMILY SSF52540 4 242 7.37E-91 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07020 94864c10efdd27daf121e4bf30c358b7 363 Gene3D G3DSA:3.40.50.300 1 238 3.2E-77 T 31-10-2018 N186_08380 78355851397b03d946165f99c4fef6cb 352 SUPERFAMILY SSF52540 14 315 4.27E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08380 78355851397b03d946165f99c4fef6cb 352 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 191 5.5E-55 T 31-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 N186_08380 78355851397b03d946165f99c4fef6cb 352 SMART SM00382 39 199 1.3E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_08380 78355851397b03d946165f99c4fef6cb 352 Gene3D G3DSA:1.10.8.300 225 338 2.5E-24 T 31-10-2018 N186_08380 78355851397b03d946165f99c4fef6cb 352 PIRSF PIRSF002849 1 329 1.4E-102 T 31-10-2018 N186_08380 78355851397b03d946165f99c4fef6cb 352 Gene3D G3DSA:3.40.50.300 23 207 2.8E-39 T 31-10-2018 N186_08490 78135d257a0744c27719e9f0e2bc9817 625 SUPERFAMILY SSF48310 231 610 2.88E-78 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_08490 78135d257a0744c27719e9f0e2bc9817 625 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 221 5.9E-60 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_08490 78135d257a0744c27719e9f0e2bc9817 625 SMART SM00790 6 223 6.8E-81 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_08490 78135d257a0744c27719e9f0e2bc9817 625 SUPERFAMILY SSF56228 4 225 7.98E-56 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily N186_08490 78135d257a0744c27719e9f0e2bc9817 625 Gene3D G3DSA:3.60.9.10 3 226 3.8E-69 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily N186_08490 78135d257a0744c27719e9f0e2bc9817 625 Gene3D G3DSA:1.10.599.10 253 608 4.5E-70 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 N186_08490 78135d257a0744c27719e9f0e2bc9817 625 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 250 608 1.7E-72 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_08490 78135d257a0744c27719e9f0e2bc9817 625 Gene3D G3DSA:1.10.569.10 255 448 4.5E-70 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 N186_03850 4b58966f7b677458c5fea1c21052d4d1 237 SMART SM00948 10 32 1.9E-11 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_03850 4b58966f7b677458c5fea1c21052d4d1 237 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 1.5E-95 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 N186_03850 4b58966f7b677458c5fea1c21052d4d1 237 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 7.2E-15 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_03850 4b58966f7b677458c5fea1c21052d4d1 237 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_03850 4b58966f7b677458c5fea1c21052d4d1 237 Pfam PF00227 Proteasome subunit 33 215 4.5E-60 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_03850 4b58966f7b677458c5fea1c21052d4d1 237 SUPERFAMILY SSF56235 9 236 5.09E-78 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_03850 4b58966f7b677458c5fea1c21052d4d1 237 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 42.737 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 N186_03850 4b58966f7b677458c5fea1c21052d4d1 237 Gene3D G3DSA:3.60.20.10 5 237 2.0E-83 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_03115 b44690e26d4bcaab3919c86494231955 73 SMART SM00651 7 71 4.0E-23 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type N186_03115 b44690e26d4bcaab3919c86494231955 73 Gene3D G3DSA:2.30.30.100 3 73 2.4E-24 T 31-10-2018 N186_03115 b44690e26d4bcaab3919c86494231955 73 Pfam PF01423 LSM domain 9 71 2.2E-22 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type N186_03115 b44690e26d4bcaab3919c86494231955 73 SUPERFAMILY SSF50182 4 72 8.8E-21 T 31-10-2018 IPR010920 LSM domain superfamily N186_00135 4024ff8b46e43e7ed29b6d6be9a6d4c8 65 Pfam PF01867 CRISPR associated protein Cas1 2 27 1.1E-6 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 N186_00135 4024ff8b46e43e7ed29b6d6be9a6d4c8 65 Gene3D G3DSA:1.20.120.920 1 63 1.8E-7 T 31-10-2018 N186_04050 3659553082ec11854c437c951435bc64 225 PIRSF PIRSF006578 2 205 5.1E-45 T 31-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E N186_04050 3659553082ec11854c437c951435bc64 225 Gene3D G3DSA:3.30.1330.130 1 165 8.6E-39 T 31-10-2018 N186_04050 3659553082ec11854c437c951435bc64 225 SUPERFAMILY SSF143555 3 163 1.7E-40 T 31-10-2018 N186_04050 3659553082ec11854c437c951435bc64 225 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 13 153 5.1E-33 T 31-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain N186_04050 3659553082ec11854c437c951435bc64 225 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 170 203 3.2E-7 T 31-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 N186_03955 68cb077e238b4125022d05c3fa48cc32 131 Gene3D G3DSA:3.40.50.1010 1 131 1.4E-31 T 31-10-2018 N186_03955 68cb077e238b4125022d05c3fa48cc32 131 SUPERFAMILY SSF88723 4 128 1.21E-24 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_03955 68cb077e238b4125022d05c3fa48cc32 131 Pfam PF01850 PIN domain 5 115 1.2E-11 T 31-10-2018 IPR002716 PIN domain N186_02185 2b91c55df7a66bd3691c65ed5e6279c5 401 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 N186_02185 2b91c55df7a66bd3691c65ed5e6279c5 401 Pfam PF00155 Aminotransferase class I and II 31 391 9.1E-51 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 N186_02185 2b91c55df7a66bd3691c65ed5e6279c5 401 Gene3D G3DSA:3.90.1150.10 31 392 5.4E-104 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 N186_02185 2b91c55df7a66bd3691c65ed5e6279c5 401 SUPERFAMILY SSF53383 2 396 8.2E-100 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase N186_02185 2b91c55df7a66bd3691c65ed5e6279c5 401 Gene3D G3DSA:3.40.640.10 65 286 5.4E-104 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 N186_00015 ce8503779aa37b068f68e1d1a00e17a7 175 PIRSF PIRSF024492 2 175 1.4E-51 T 31-10-2018 IPR014519 Uncharacterised conserved protein UCP024492 N186_00015 ce8503779aa37b068f68e1d1a00e17a7 175 Pfam PF04343 Protein of unknown function, DUF488 14 139 4.5E-26 T 31-10-2018 IPR007438 Protein of unknown function DUF488 N186_05185 149ff31a50b30ad915776029368ac813 295 Gene3D G3DSA:3.30.230.10 27 156 8.1E-16 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup N186_05185 149ff31a50b30ad915776029368ac813 295 Pfam PF00288 GHMP kinases N terminal domain 85 135 4.4E-8 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 N186_05185 149ff31a50b30ad915776029368ac813 295 PIRSF PIRSF016896 3 290 1.1E-56 T 31-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 N186_05185 149ff31a50b30ad915776029368ac813 295 SUPERFAMILY SSF54211 8 135 1.59E-17 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_04325 f338bbaadc2898834182fe55e8b35af2 418 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 53 267 2.9E-15 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_04325 f338bbaadc2898834182fe55e8b35af2 418 SUPERFAMILY SSF56770 42 372 5.72E-50 T 31-10-2018 N186_04325 f338bbaadc2898834182fe55e8b35af2 418 Gene3D G3DSA:3.40.50.700 37 289 8.6E-45 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily N186_04325 f338bbaadc2898834182fe55e8b35af2 418 PIRSF PIRSF000310 1 417 2.8E-74 T 31-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 N186_04325 f338bbaadc2898834182fe55e8b35af2 418 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 290 370 1.4E-23 T 31-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal N186_04325 f338bbaadc2898834182fe55e8b35af2 418 Gene3D G3DSA:4.10.480.10 290 372 1.2E-24 T 31-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily N186_04440 eeda13da7199952a0f39736e0bd82866 432 Gene3D G3DSA:3.40.50.720 203 362 4.4E-173 T 31-10-2018 N186_04440 eeda13da7199952a0f39736e0bd82866 432 SMART SM00997 201 362 4.2E-106 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 N186_04440 eeda13da7199952a0f39736e0bd82866 432 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 2 428 4.2E-72 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 N186_04440 eeda13da7199952a0f39736e0bd82866 432 SUPERFAMILY SSF51735 201 363 9.44E-66 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_04440 eeda13da7199952a0f39736e0bd82866 432 Gene3D G3DSA:3.40.50.1480 5 423 4.4E-173 T 31-10-2018 N186_04440 eeda13da7199952a0f39736e0bd82866 432 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 3 431 1.2E-187 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 N186_04440 eeda13da7199952a0f39736e0bd82866 432 PIRSF PIRSF001109 1 432 1.8E-186 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 N186_04440 eeda13da7199952a0f39736e0bd82866 432 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 201 361 3.0E-52 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 N186_04440 eeda13da7199952a0f39736e0bd82866 432 SMART SM00996 2 432 3.0E-152 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 N186_04440 eeda13da7199952a0f39736e0bd82866 432 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 432 47.4 T 31-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 N186_04440 eeda13da7199952a0f39736e0bd82866 432 SUPERFAMILY SSF52283 1 431 2.55E-93 T 31-10-2018 N186_04440 eeda13da7199952a0f39736e0bd82866 432 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 223 239 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 N186_05755 1133c974326f87f27d2149b63a8cb316 113 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 13 33 4.9E-9 T 31-10-2018 N186_05755 1133c974326f87f27d2149b63a8cb316 113 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 33 52 4.9E-9 T 31-10-2018 N186_05755 1133c974326f87f27d2149b63a8cb316 113 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 52 70 4.9E-9 T 31-10-2018 N186_05755 1133c974326f87f27d2149b63a8cb316 113 Gene3D G3DSA:1.20.1270.30 33 111 2.9E-5 T 31-10-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 N186_05755 1133c974326f87f27d2149b63a8cb316 113 Pfam PF02416 mttA/Hcf106 family 16 63 1.3E-15 T 31-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 N186_05755 1133c974326f87f27d2149b63a8cb316 113 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 13 74 15.917 T 31-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 N186_07085 afba7ef7e53b0c451e1dfb3f37e804b6 283 PIRSF PIRSF006816 5 262 5.8E-69 T 31-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 N186_07085 afba7ef7e53b0c451e1dfb3f37e804b6 283 Gene3D G3DSA:2.40.30.10 4 98 3.4E-21 T 31-10-2018 N186_07085 afba7ef7e53b0c451e1dfb3f37e804b6 283 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 220 255 1.6E-13 T 31-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain N186_07085 afba7ef7e53b0c451e1dfb3f37e804b6 283 Gene3D G3DSA:3.40.50.80 106 210 4.8E-39 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain N186_07085 afba7ef7e53b0c451e1dfb3f37e804b6 283 SUPERFAMILY SSF52343 95 256 1.44E-35 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain N186_07085 afba7ef7e53b0c451e1dfb3f37e804b6 283 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 224 232 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 N186_07085 afba7ef7e53b0c451e1dfb3f37e804b6 283 Pfam PF00175 Oxidoreductase NAD-binding domain 111 203 5.2E-7 T 31-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 N186_07085 afba7ef7e53b0c451e1dfb3f37e804b6 283 SUPERFAMILY SSF63380 7 98 3.14E-19 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel N186_09190 e563d9e1adace43853feb170c133e759 160 Gene3D G3DSA:1.20.120.330 4 153 1.3E-7 T 31-10-2018 N186_09190 e563d9e1adace43853feb170c133e759 160 Pfam PF05168 HEPN domain 5 54 1.3E-8 T 31-10-2018 IPR007842 HEPN domain N186_09190 e563d9e1adace43853feb170c133e759 160 SUPERFAMILY SSF81593 7 55 9.42E-6 T 31-10-2018 N186_03185 b23e12e5b9a92a23c9a7bc3500186a08 218 Pfam PF01864 CDP-archaeol synthase 52 218 2.6E-35 T 31-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 N186_03185 b23e12e5b9a92a23c9a7bc3500186a08 218 Hamap MF_01117 CDP-archaeol synthase [carS]. 59 218 24.658 T 31-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 Gene3D G3DSA:3.40.50.300 5 174 3.4E-47 T 31-10-2018 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 SMART SM00174 10 171 4.1E-5 T 31-10-2018 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 SMART SM00175 8 171 5.7E-32 T 31-10-2018 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 PRINTS PR00449 Transforming protein P21 ras signature 110 123 1.6E-25 T 31-10-2018 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 PRINTS PR00449 Transforming protein P21 ras signature 49 71 1.6E-25 T 31-10-2018 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 PRINTS PR00449 Transforming protein P21 ras signature 8 29 1.6E-25 T 31-10-2018 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 PRINTS PR00449 Transforming protein P21 ras signature 31 47 1.6E-25 T 31-10-2018 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 PRINTS PR00449 Transforming protein P21 ras signature 146 168 1.6E-25 T 31-10-2018 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 164 1.2E-22 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 SMART SM00173 9 171 4.4E-10 T 31-10-2018 N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 SUPERFAMILY SSF52540 6 170 7.72E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01315 35e2d6cfa2c5a54f2aca4f8c8de5f8aa 174 Pfam PF00071 Ras family 9 169 1.7E-38 T 31-10-2018 IPR001806 Small GTPase GO:0003924|GO:0005525 N186_08995 8b6f94c147f971b56d0a80b017599b1b 433 Pfam PF03577 Peptidase family C69 82 214 2.1E-13 T 31-10-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 N186_08995 8b6f94c147f971b56d0a80b017599b1b 433 Gene3D G3DSA:3.60.60.10 2 306 1.5E-24 T 31-10-2018 N186_00150 481536584ceaea5981c9cfafe99d82cf 330 SUPERFAMILY SSF55326 15 143 3.31E-23 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily N186_00150 481536584ceaea5981c9cfafe99d82cf 330 Gene3D G3DSA:3.30.1330.10 4 139 4.6E-26 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily N186_00150 481536584ceaea5981c9cfafe99d82cf 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 35 138 1.0E-13 T 31-10-2018 IPR016188 PurM-like, N-terminal domain N186_00150 481536584ceaea5981c9cfafe99d82cf 330 SUPERFAMILY SSF56042 146 314 1.79E-32 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily N186_00150 481536584ceaea5981c9cfafe99d82cf 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 151 305 4.3E-24 T 31-10-2018 IPR010918 PurM-like, C-terminal domain N186_00150 481536584ceaea5981c9cfafe99d82cf 330 PIRSF PIRSF005644 4 330 8.7E-83 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE N186_00150 481536584ceaea5981c9cfafe99d82cf 330 Gene3D G3DSA:3.90.650.10 144 329 1.3E-42 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily N186_03195 4e3818bbb963a494ae8dcf948528633d 105 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 71 100 4.9E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_03195 4e3818bbb963a494ae8dcf948528633d 105 Gene3D G3DSA:2.10.260.10 17 103 2.8E-15 T 31-10-2018 N186_03195 4e3818bbb963a494ae8dcf948528633d 105 SMART SM00966 21 66 5.2 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_03195 4e3818bbb963a494ae8dcf948528633d 105 SMART SM00966 67 104 0.056 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_03195 4e3818bbb963a494ae8dcf948528633d 105 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 70 98 1.8E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_03195 4e3818bbb963a494ae8dcf948528633d 105 SUPERFAMILY SSF89447 66 98 2.09E-6 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_03275 317cdc0e21cee0b9b73f94604382f8d9 86 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 13 85 4.0E-17 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 N186_03275 317cdc0e21cee0b9b73f94604382f8d9 86 SUPERFAMILY SSF158436 6 86 1.44E-30 T 31-10-2018 N186_03275 317cdc0e21cee0b9b73f94604382f8d9 86 Hamap MF_00342 UPF0147 protein . 4 85 29.958 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 N186_03275 317cdc0e21cee0b9b73f94604382f8d9 86 Gene3D G3DSA:1.20.1440.50 5 86 7.3E-30 T 31-10-2018 IPR023130 Ta0600-like superfamily N186_03275 317cdc0e21cee0b9b73f94604382f8d9 86 Pfam PF03685 Uncharacterised protein family (UPF0147) 7 84 1.1E-32 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 Gene3D G3DSA:3.40.1380.20 334 449 1.2E-139 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 Gene3D G3DSA:3.20.20.60 3 333 1.2E-139 T 31-10-2018 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 ProSitePatterns PS00110 Pyruvate kinase active site signature. 210 222 - T 31-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 Pfam PF02887 Pyruvate kinase, alpha/beta domain 349 458 1.4E-21 T 31-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 SUPERFAMILY SSF50800 69 162 7.85E-13 T 31-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 SUPERFAMILY SSF52935 318 461 3.27E-25 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 PRINTS PR01050 Pyruvate kinase family signature 212 238 4.7E-49 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 PRINTS PR01050 Pyruvate kinase family signature 264 288 4.7E-49 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 PRINTS PR01050 Pyruvate kinase family signature 181 195 4.7E-49 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 PRINTS PR01050 Pyruvate kinase family signature 308 324 4.7E-49 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 PRINTS PR01050 Pyruvate kinase family signature 239 263 4.7E-49 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 PRINTS PR01050 Pyruvate kinase family signature 289 307 4.7E-49 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 PRINTS PR01050 Pyruvate kinase family signature 58 74 4.7E-49 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 Pfam PF00224 Pyruvate kinase, barrel domain 1 332 8.3E-95 T 31-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 SUPERFAMILY SSF51621 1 333 1.31E-80 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 Gene3D G3DSA:2.40.33.10 70 162 1.2E-139 T 31-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_02660 5e7bac5976f634dbcdb32d99b35197fd 465 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 460 4.3E-136 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 N186_04950 8cba8a0c16166fc65786584e12cd8039 386 Gene3D G3DSA:3.30.9.10 69 354 2.8E-91 T 31-10-2018 N186_04950 8cba8a0c16166fc65786584e12cd8039 386 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 2 294 8.3E-67 T 31-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 N186_04950 8cba8a0c16166fc65786584e12cd8039 386 Pfam PF01494 FAD binding domain 3 312 5.6E-19 T 31-10-2018 IPR002938 FAD-binding domain GO:0071949 N186_04950 8cba8a0c16166fc65786584e12cd8039 386 SUPERFAMILY SSF51905 1 324 2.4E-35 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_04950 8cba8a0c16166fc65786584e12cd8039 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.2E-11 T 31-10-2018 N186_04950 8cba8a0c16166fc65786584e12cd8039 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 139 154 3.2E-11 T 31-10-2018 N186_04950 8cba8a0c16166fc65786584e12cd8039 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 260 275 3.2E-11 T 31-10-2018 N186_04950 8cba8a0c16166fc65786584e12cd8039 386 Gene3D G3DSA:3.50.50.60 2 334 2.8E-91 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_07380 3b4851c56feb6b9fb3b289453ac0e7da 424 Pfam PF04055 Radical SAM superfamily 9 142 4.2E-9 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_07380 3b4851c56feb6b9fb3b289453ac0e7da 424 SUPERFAMILY SSF102114 6 388 1.26E-44 T 31-10-2018 N186_07380 3b4851c56feb6b9fb3b289453ac0e7da 424 Pfam PF13186 Iron-sulfur cluster-binding domain 307 387 1.7E-14 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain N186_07380 3b4851c56feb6b9fb3b289453ac0e7da 424 Pfam PF13394 4Fe-4S single cluster domain 12 95 4.2E-7 T 31-10-2018 N186_02270 e21c5198571179c18db3ee2c09b548d8 289 Pfam PF01875 Memo-like protein 10 285 6.4E-81 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 N186_02270 e21c5198571179c18db3ee2c09b548d8 289 SUPERFAMILY SSF53213 79 251 2.33E-9 T 31-10-2018 N186_02270 e21c5198571179c18db3ee2c09b548d8 289 Hamap MF_00055 MEMO1 family protein . 6 288 56.362 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 N186_02270 e21c5198571179c18db3ee2c09b548d8 289 Gene3D G3DSA:3.40.830.10 5 288 6.5E-67 T 31-10-2018 N186_02270 e21c5198571179c18db3ee2c09b548d8 289 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 8 287 7.2E-92 T 31-10-2018 N186_03920 b7f11ac603e41c3d79fbfe0f104bef35 424 Gene3D G3DSA:3.30.420.570 169 388 5.5E-210 T 31-10-2018 N186_03920 b7f11ac603e41c3d79fbfe0f104bef35 424 Gene3D G3DSA:3.30.420.40 6 417 5.5E-210 T 31-10-2018 N186_03920 b7f11ac603e41c3d79fbfe0f104bef35 424 SUPERFAMILY SSF53067 170 423 2.33E-26 T 31-10-2018 N186_03920 b7f11ac603e41c3d79fbfe0f104bef35 424 SMART SM00268 28 422 5.7E-7 T 31-10-2018 IPR004000 Actin family N186_03920 b7f11ac603e41c3d79fbfe0f104bef35 424 Pfam PF00022 Actin 146 398 1.8E-15 T 31-10-2018 IPR004000 Actin family N186_06995 ae83e31303e81e6a28f7340502b61b4c 435 SUPERFAMILY SSF51556 58 353 1.79E-73 T 31-10-2018 IPR032466 Metal-dependent hydrolase N186_06995 ae83e31303e81e6a28f7340502b61b4c 435 SUPERFAMILY SSF51338 17 416 1.98E-17 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 N186_06995 ae83e31303e81e6a28f7340502b61b4c 435 ProSitePatterns PS00483 Dihydroorotase signature 2. 293 304 - T 31-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 N186_06995 ae83e31303e81e6a28f7340502b61b4c 435 Pfam PF01979 Amidohydrolase family 54 406 4.6E-22 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 N186_06995 ae83e31303e81e6a28f7340502b61b4c 435 Gene3D G3DSA:3.20.20.140 11 410 7.9E-97 T 31-10-2018 N186_06995 ae83e31303e81e6a28f7340502b61b4c 435 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 19 410 2.1E-93 T 31-10-2018 N186_07690 0569461871ea23e34f693ed3cfb42825 209 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 8.2E-32 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 8.2E-32 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 8.2E-32 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 8.2E-32 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 8.2E-32 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 Gene3D G3DSA:3.40.630.20 1 209 5.8E-65 T 31-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 PIRSF PIRSF015592 1 209 4.5E-63 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 31-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 Pfam PF01470 Pyroglutamyl peptidase 2 203 3.6E-62 T 31-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 204 3.6E-66 T 31-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 N186_07690 0569461871ea23e34f693ed3cfb42825 209 SUPERFAMILY SSF53182 2 207 5.23E-60 T 31-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 N186_04870 fe5d1e7eae239d50d0ae2cd20ac1c960 610 Gene3D G3DSA:3.20.20.70 144 411 5.9E-33 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_04870 fe5d1e7eae239d50d0ae2cd20ac1c960 610 SUPERFAMILY SSF102114 140 433 2.22E-41 T 31-10-2018 N186_04870 fe5d1e7eae239d50d0ae2cd20ac1c960 610 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 156 167 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_04870 fe5d1e7eae239d50d0ae2cd20ac1c960 610 Pfam PF04055 Radical SAM superfamily 154 312 1.5E-16 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_04870 fe5d1e7eae239d50d0ae2cd20ac1c960 610 Pfam PF13394 4Fe-4S single cluster domain 155 238 1.2E-5 T 31-10-2018 N186_07920 4e9eeac0add468844784babc375e4f6c 165 Gene3D G3DSA:1.20.120.330 37 165 3.0E-38 T 31-10-2018 N186_07920 4e9eeac0add468844784babc375e4f6c 165 Pfam PF05942 Archaeal PaREP1/PaREP8 family 43 155 1.3E-29 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_04405 53a148a8494f401922e7aeb490186f0f 125 Pfam PF01042 Endoribonuclease L-PSP 8 124 2.9E-43 T 31-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 N186_04405 53a148a8494f401922e7aeb490186f0f 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 124 2.2E-50 T 31-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 N186_04405 53a148a8494f401922e7aeb490186f0f 125 SUPERFAMILY SSF55298 3 124 9.27E-46 T 31-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 N186_04405 53a148a8494f401922e7aeb490186f0f 125 Gene3D G3DSA:3.30.1330.40 2 125 1.8E-53 T 31-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 N186_06830 6bb692045edaa63d1f4726483d5b73d9 125 SUPERFAMILY SSF81343 15 123 1.05E-15 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 N186_06830 6bb692045edaa63d1f4726483d5b73d9 125 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 18 115 6.8E-9 T 31-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 N186_06830 6bb692045edaa63d1f4726483d5b73d9 125 Gene3D G3DSA:1.20.1300.10 17 124 3.2E-8 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 N186_03235 73493d985a7697ebf3b86f6256b75d10 175 SUPERFAMILY SSF52374 4 160 7.6E-26 T 31-10-2018 N186_03235 73493d985a7697ebf3b86f6256b75d10 175 Gene3D G3DSA:3.40.50.620 2 173 4.4E-42 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_03235 73493d985a7697ebf3b86f6256b75d10 175 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 63 6.7E-14 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 N186_03235 73493d985a7697ebf3b86f6256b75d10 175 Pfam PF01467 Cytidylyltransferase-like 7 67 3.1E-12 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 N186_03235 73493d985a7697ebf3b86f6256b75d10 175 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 175 71.404 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 N186_04385 f7eda02b8100de68e4acad7b11461417 338 Gene3D G3DSA:1.10.600.10 3 338 7.1E-103 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily N186_04385 f7eda02b8100de68e4acad7b11461417 338 SUPERFAMILY SSF48576 20 337 3.96E-77 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily N186_04385 f7eda02b8100de68e4acad7b11461417 338 Pfam PF00348 Polyprenyl synthetase 30 289 9.0E-59 T 31-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 N186_04385 f7eda02b8100de68e4acad7b11461417 338 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 80 94 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site N186_04385 f7eda02b8100de68e4acad7b11461417 338 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 216 228 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site N186_05990 00b001b01da752c305dfa9736eca17c1 247 Pfam PF01939 Endonuclease NucS 15 227 7.6E-53 T 31-10-2018 IPR002793 Endonuclease NucS GO:0004519 N186_05990 00b001b01da752c305dfa9736eca17c1 247 Gene3D G3DSA:2.70.180.20 2 112 1.8E-31 T 31-10-2018 N186_05990 00b001b01da752c305dfa9736eca17c1 247 Gene3D G3DSA:3.40.1350.10 113 228 4.3E-30 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 N186_05990 00b001b01da752c305dfa9736eca17c1 247 Hamap MF_00722 Endonuclease NucS [nucS]. 16 234 31.743 T 31-10-2018 IPR002793 Endonuclease NucS GO:0004519 N186_05330 4dbaea9cbfcdd9dd2a83307a5f50213f 261 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 206 223 - T 31-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 N186_05330 4dbaea9cbfcdd9dd2a83307a5f50213f 261 Gene3D G3DSA:3.40.1180.10 12 261 6.0E-96 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 N186_05330 4dbaea9cbfcdd9dd2a83307a5f50213f 261 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 28 259 4.5E-81 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 N186_05330 4dbaea9cbfcdd9dd2a83307a5f50213f 261 SUPERFAMILY SSF64005 24 255 2.62E-81 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 N186_05330 4dbaea9cbfcdd9dd2a83307a5f50213f 261 Pfam PF01255 Putative undecaprenyl diphosphate synthase 35 260 2.4E-77 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 N186_05330 4dbaea9cbfcdd9dd2a83307a5f50213f 261 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 28 261 39.488 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 N186_01470 ecd9428bf7bb7f97dd48123b0f309de2 406 PIRSF PIRSF000390 13 404 8.9E-114 T 31-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase N186_01470 ecd9428bf7bb7f97dd48123b0f309de2 406 Gene3D G3DSA:3.40.640.10 13 254 1.8E-101 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 N186_01470 ecd9428bf7bb7f97dd48123b0f309de2 406 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 24 397 9.7E-124 T 31-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase N186_01470 ecd9428bf7bb7f97dd48123b0f309de2 406 Gene3D G3DSA:3.90.1150.10 256 404 4.2E-30 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 N186_01470 ecd9428bf7bb7f97dd48123b0f309de2 406 SUPERFAMILY SSF53383 19 401 1.22E-114 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase N186_06935 a484566862c62d803d6a14bc21c1b443 501 Gene3D G3DSA:3.30.420.40 249 501 8.5E-62 T 31-10-2018 N186_06935 a484566862c62d803d6a14bc21c1b443 501 PIRSF PIRSF000538 1 501 2.4E-107 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 N186_06935 a484566862c62d803d6a14bc21c1b443 501 SUPERFAMILY SSF53067 3 246 4.06E-57 T 31-10-2018 N186_06935 a484566862c62d803d6a14bc21c1b443 501 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 245 9.5E-50 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 N186_06935 a484566862c62d803d6a14bc21c1b443 501 SUPERFAMILY SSF53067 250 494 2.72E-46 T 31-10-2018 N186_06935 a484566862c62d803d6a14bc21c1b443 501 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 448 2.0E-30 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 N186_06935 a484566862c62d803d6a14bc21c1b443 501 Gene3D G3DSA:3.30.420.40 2 246 1.8E-60 T 31-10-2018 N186_01540 dfe82273d57c6f3d355d9941e22d9e7c 129 Pfam PF08753 NikR C terminal nickel binding domain 57 113 1.8E-8 T 31-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal N186_01540 dfe82273d57c6f3d355d9941e22d9e7c 129 SUPERFAMILY SSF55021 52 117 5.95E-13 T 31-10-2018 N186_01540 dfe82273d57c6f3d355d9941e22d9e7c 129 Gene3D G3DSA:3.30.70.1150 52 117 6.7E-10 T 31-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal N186_07925 f7188e2f0be67eefb4423091bb6d9d12 216 Pfam PF12644 Protein of unknown function (DUF3782) 58 135 1.3E-12 T 31-10-2018 IPR024271 Protein of unknown function DUF3782 N186_07925 f7188e2f0be67eefb4423091bb6d9d12 216 Pfam PF07788 PD-(D/E)XK nuclease superfamily 141 208 3.4E-7 T 31-10-2018 IPR012431 PD-(D/E)XK nuclease N186_07925 f7188e2f0be67eefb4423091bb6d9d12 216 SUPERFAMILY SSF52980 3 212 5.09E-27 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_06860 29b0ae5915772d94cc0edc9d73995411 287 Gene3D G3DSA:1.10.3720.10 46 283 2.4E-63 T 31-10-2018 IPR035906 MetI-like superfamily N186_06860 29b0ae5915772d94cc0edc9d73995411 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 274 8.5E-17 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_06860 29b0ae5915772d94cc0edc9d73995411 287 SUPERFAMILY SSF161098 50 274 5.36E-56 T 31-10-2018 IPR035906 MetI-like superfamily N186_06415 9ebfbe98117c85d14cc5de4b7e5a9a0c 337 Gene3D G3DSA:3.30.360.10 124 320 2.3E-105 T 31-10-2018 N186_06415 9ebfbe98117c85d14cc5de4b7e5a9a0c 337 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 201 1.8E-9 T 31-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 N186_06415 9ebfbe98117c85d14cc5de4b7e5a9a0c 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 123 2.0E-31 T 31-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 N186_06415 9ebfbe98117c85d14cc5de4b7e5a9a0c 337 Gene3D G3DSA:3.40.50.720 4 306 2.3E-105 T 31-10-2018 N186_06415 9ebfbe98117c85d14cc5de4b7e5a9a0c 337 SUPERFAMILY SSF51735 3 149 1.01E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_06415 9ebfbe98117c85d14cc5de4b7e5a9a0c 337 SUPERFAMILY SSF55347 130 304 1.08E-29 T 31-10-2018 N186_06190 68053bbb4dd186bd579fd201f1904140 87 Gene3D G3DSA:3.30.110.60 7 86 1.0E-14 T 31-10-2018 IPR035920 YhbY-like superfamily N186_06190 68053bbb4dd186bd579fd201f1904140 87 Pfam PF01985 CRS1 / YhbY (CRM) domain 12 80 8.4E-10 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 N186_06190 68053bbb4dd186bd579fd201f1904140 87 SMART SM01103 1 82 2.2E-14 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 N186_06190 68053bbb4dd186bd579fd201f1904140 87 SUPERFAMILY SSF75471 12 80 1.57E-12 T 31-10-2018 IPR035920 YhbY-like superfamily N186_06190 68053bbb4dd186bd579fd201f1904140 87 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 12 80 1.0E-6 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 Gene3D G3DSA:1.10.260.40 6 59 8.8E-17 T 31-10-2018 N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 Gene3D G3DSA:3.10.580.10 60 192 7.6E-27 T 31-10-2018 N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 SMART SM00116 73 122 5.5E-6 T 31-10-2018 IPR000644 CBS domain N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 SMART SM00116 140 186 0.0052 T 31-10-2018 IPR000644 CBS domain N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 SMART SM00530 8 63 2.1E-13 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 PIRSF PIRSF037253 1 189 3.3E-56 T 31-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 Pfam PF13560 Helix-turn-helix domain 8 57 3.3E-14 T 31-10-2018 N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 Pfam PF00571 CBS domain 68 121 4.3E-9 T 31-10-2018 IPR000644 CBS domain N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 Pfam PF00571 CBS domain 134 187 1.1E-9 T 31-10-2018 IPR000644 CBS domain N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 SUPERFAMILY SSF54631 62 186 1.39E-24 T 31-10-2018 N186_04110 77cc5c6a69bd4ae0d9e4e0bedd87f965 192 SUPERFAMILY SSF47413 6 61 4.83E-16 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 N186_03605 769997e4468a88bf3f0957d022d43014 151 Gene3D G3DSA:3.40.1350.10 8 81 1.6E-5 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 N186_03605 769997e4468a88bf3f0957d022d43014 151 SUPERFAMILY SSF52980 16 63 2.07E-5 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_05875 59da2d81947df9505d118ec75a4abcc1 82 SUPERFAMILY SSF54909 8 80 6.57E-15 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel N186_05875 59da2d81947df9505d118ec75a4abcc1 82 Pfam PF01037 Lrp/AsnC ligand binding domain 17 79 2.4E-13 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain N186_05875 59da2d81947df9505d118ec75a4abcc1 82 Gene3D G3DSA:3.30.70.920 8 79 5.6E-20 T 31-10-2018 N186_03675 90ce7ff0943944facec5b4f09a94bcc1 254 SUPERFAMILY SSF109604 13 100 1.66E-7 T 31-10-2018 N186_03675 90ce7ff0943944facec5b4f09a94bcc1 254 Gene3D G3DSA:1.10.3210.30 2 211 1.1E-15 T 31-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily N186_03675 90ce7ff0943944facec5b4f09a94bcc1 254 Pfam PF01966 HD domain 16 98 2.5E-7 T 31-10-2018 IPR006674 HD domain N186_03050 d1c27d759f298ce40b16891dce4f73b1 435 Gene3D G3DSA:3.40.1670.10 303 417 2.4E-38 T 31-10-2018 N186_03050 d1c27d759f298ce40b16891dce4f73b1 435 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 14 392 9.7E-95 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 N186_03050 d1c27d759f298ce40b16891dce4f73b1 435 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 53 417 1.4E-102 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 N186_03050 d1c27d759f298ce40b16891dce4f73b1 435 SUPERFAMILY SSF50475 8 285 2.47E-65 T 31-10-2018 N186_03050 d1c27d759f298ce40b16891dce4f73b1 435 SUPERFAMILY SSF143968 291 424 2.88E-41 T 31-10-2018 N186_09090 205a01781543d108c9653b12829e3d32 86 Gene3D G3DSA:1.20.120.330 3 85 1.2E-16 T 31-10-2018 N186_09090 205a01781543d108c9653b12829e3d32 86 Pfam PF05168 HEPN domain 10 70 2.0E-17 T 31-10-2018 IPR007842 HEPN domain N186_09090 205a01781543d108c9653b12829e3d32 86 SMART SM00748 13 81 5.8E-5 T 31-10-2018 IPR007842 HEPN domain N186_09090 205a01781543d108c9653b12829e3d32 86 SUPERFAMILY SSF81593 13 71 1.26E-15 T 31-10-2018 N186_09735 a721a86f37a44983c0126bdb7b20cefa 291 Gene3D G3DSA:1.20.1740.10 1 291 7.2E-38 T 31-10-2018 N186_09735 a721a86f37a44983c0126bdb7b20cefa 291 Pfam PF13520 Amino acid permease 2 264 1.4E-24 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 N186_03870 cb09c3f030cc8f4e2969bc78b8783223 280 SUPERFAMILY SSF54211 7 213 2.58E-52 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_03870 cb09c3f030cc8f4e2969bc78b8783223 280 Pfam PF03725 3' exoribonuclease family, domain 2 191 255 1.0E-17 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 N186_03870 cb09c3f030cc8f4e2969bc78b8783223 280 Pfam PF01138 3' exoribonuclease family, domain 1 33 168 6.0E-26 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 N186_03870 cb09c3f030cc8f4e2969bc78b8783223 280 Gene3D G3DSA:3.30.230.70 2 269 4.1E-83 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 N186_03870 cb09c3f030cc8f4e2969bc78b8783223 280 SUPERFAMILY SSF55666 186 268 3.93E-24 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 N186_03870 cb09c3f030cc8f4e2969bc78b8783223 280 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 4 267 44.21 T 31-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 N186_09600 b63ae54355777ad7d592e218466ee747 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 42 2.5E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_09600 b63ae54355777ad7d592e218466ee747 84 SMART SM00966 3 46 3.3E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_09600 b63ae54355777ad7d592e218466ee747 84 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 41 1.7E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_09600 b63ae54355777ad7d592e218466ee747 84 SUPERFAMILY SSF89447 3 62 2.62E-10 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_09600 b63ae54355777ad7d592e218466ee747 84 Gene3D G3DSA:2.10.260.10 2 41 5.8E-9 T 31-10-2018 N186_06600 adf7b2dd8039773c4aabecdbd7cb7e62 161 SUPERFAMILY SSF143243 12 152 1.31E-43 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06600 adf7b2dd8039773c4aabecdbd7cb7e62 161 Gene3D G3DSA:3.30.460.80 4 132 7.0E-31 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06600 adf7b2dd8039773c4aabecdbd7cb7e62 161 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 33 152 2.5E-35 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06600 adf7b2dd8039773c4aabecdbd7cb7e62 161 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 81 127 8.0E-6 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_04605 81f30f4a87e634e4461216a9e44e029f 112 Gene3D G3DSA:1.10.287.370 5 110 2.4E-22 T 31-10-2018 IPR009053 Prefoldin N186_04605 81f30f4a87e634e4461216a9e44e029f 112 Pfam PF01920 Prefoldin subunit 5 103 1.5E-14 T 31-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 N186_04605 81f30f4a87e634e4461216a9e44e029f 112 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 112 27.083 T 31-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 N186_04605 81f30f4a87e634e4461216a9e44e029f 112 SUPERFAMILY SSF46579 5 103 3.4E-16 T 31-10-2018 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.4E-19 T 31-10-2018 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 1.4E-19 T 31-10-2018 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 1.4E-19 T 31-10-2018 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 1.4E-19 T 31-10-2018 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 SUPERFAMILY SSF51905 1 325 9.55E-44 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 Gene3D G3DSA:3.50.50.60 7 301 4.3E-50 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 1.2E-17 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 252 273 1.2E-17 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 1.2E-17 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 288 306 1.2E-17 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 1.2E-17 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 1.2E-17 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 208 224 1.2E-17 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 Gene3D G3DSA:3.50.50.60 124 258 4.3E-50 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_07410 18425e6acf9c6a313fff6c38b63c0f64 417 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 300 1.8E-31 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 N186_02860 7880344261665fbc15b622ee454db88b 456 Hamap MF_01264 CCA-adding enzyme [cca]. 1 456 107.64 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 N186_02860 7880344261665fbc15b622ee454db88b 456 Gene3D G3DSA:1.10.1410.30 9 269 7.3E-72 T 31-10-2018 N186_02860 7880344261665fbc15b622ee454db88b 456 Gene3D G3DSA:3.30.460.10 16 156 7.3E-72 T 31-10-2018 N186_02860 7880344261665fbc15b622ee454db88b 456 SUPERFAMILY SSF81301 1 150 1.71E-24 T 31-10-2018 N186_02860 7880344261665fbc15b622ee454db88b 456 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 7 414 7.6E-111 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 N186_02860 7880344261665fbc15b622ee454db88b 456 SUPERFAMILY SSF55003 293 430 1.1E-22 T 31-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 N186_02860 7880344261665fbc15b622ee454db88b 456 SUPERFAMILY SSF81631 160 270 6.02E-25 T 31-10-2018 N186_02860 7880344261665fbc15b622ee454db88b 456 Pfam PF09249 tRNA nucleotidyltransferase, second domain 163 269 1.0E-30 T 31-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 N186_02860 7880344261665fbc15b622ee454db88b 456 PIRSF PIRSF005335 4 445 2.4E-95 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 N186_02860 7880344261665fbc15b622ee454db88b 456 Pfam PF01909 Nucleotidyltransferase domain 47 142 1.9E-6 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_02410 7ff3ff3d13ef48973c7c3b7aaaa29bde 149 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 6 145 1.8E-27 T 31-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 N186_02410 7ff3ff3d13ef48973c7c3b7aaaa29bde 149 SUPERFAMILY SSF55729 2 148 1.6E-33 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase N186_02410 7ff3ff3d13ef48973c7c3b7aaaa29bde 149 Pfam PF00583 Acetyltransferase (GNAT) family 9 126 1.0E-21 T 31-10-2018 IPR000182 GNAT domain N186_02410 7ff3ff3d13ef48973c7c3b7aaaa29bde 149 Gene3D G3DSA:3.40.630.30 1 149 1.9E-46 T 31-10-2018 N186_06795 2058cc0756f38a3f9fca0f5b29e150ff 281 Gene3D G3DSA:3.30.70.1350 197 279 9.5E-20 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 N186_06795 2058cc0756f38a3f9fca0f5b29e150ff 281 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 7 279 2.8E-46 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 N186_06795 2058cc0756f38a3f9fca0f5b29e150ff 281 SUPERFAMILY SSF160240 201 279 2.62E-17 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 N186_06795 2058cc0756f38a3f9fca0f5b29e150ff 281 Pfam PF01545 Cation efflux family 10 197 8.4E-26 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 N186_06795 2058cc0756f38a3f9fca0f5b29e150ff 281 Pfam PF16916 Dimerisation domain of Zinc Transporter 205 278 4.8E-20 T 31-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain N186_06795 2058cc0756f38a3f9fca0f5b29e150ff 281 SUPERFAMILY SSF161111 6 199 1.83E-32 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily N186_06795 2058cc0756f38a3f9fca0f5b29e150ff 281 Gene3D G3DSA:1.20.1510.10 5 196 2.0E-33 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 SUPERFAMILY SSF52343 91 246 1.15E-28 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 Pfam PF00970 Oxidoreductase FAD-binding domain 9 94 2.6E-5 T 31-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 SUPERFAMILY SSF63380 6 96 3.76E-19 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 PRINTS PR00409 Phthalate dioxygenase reductase family signature 184 192 7.2E-5 T 31-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 PRINTS PR00409 Phthalate dioxygenase reductase family signature 69 83 7.2E-5 T 31-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 PRINTS PR00409 Phthalate dioxygenase reductase family signature 104 123 7.2E-5 T 31-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 Gene3D G3DSA:2.40.30.10 6 95 1.0E-15 T 31-10-2018 N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 Gene3D G3DSA:2.10.240.10 213 248 3.2E-6 T 31-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 PIRSF PIRSF006816 4 254 3.4E-67 T 31-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 213 247 7.1E-12 T 31-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain N186_07000 c8e55823106d4436cbe1c1fb7b6b7721 271 Gene3D G3DSA:3.40.50.80 97 204 2.2E-21 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain N186_07440 c88181496bc95d8206c4698c96fb737f 149 SUPERFAMILY SSF55811 5 137 1.35E-30 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 N186_07440 c88181496bc95d8206c4698c96fb737f 149 Gene3D G3DSA:3.90.79.10 4 139 3.9E-32 T 31-10-2018 N186_07440 c88181496bc95d8206c4698c96fb737f 149 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 N186_07440 c88181496bc95d8206c4698c96fb737f 149 Pfam PF00293 NUDIX domain 10 121 2.8E-21 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 N186_07440 c88181496bc95d8206c4698c96fb737f 149 PRINTS PR00502 NUDIX hydrolase family signature 36 50 8.1E-7 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 N186_07440 c88181496bc95d8206c4698c96fb737f 149 PRINTS PR00502 NUDIX hydrolase family signature 50 65 8.1E-7 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 N186_02900 33ca8e68bc76625698cabe0d6107be53 423 Gene3D G3DSA:1.10.150.460 178 229 9.8E-39 T 31-10-2018 N186_02900 33ca8e68bc76625698cabe0d6107be53 423 SMART SM00931 147 199 7.2E-27 T 31-10-2018 IPR012976 NOSIC N186_02900 33ca8e68bc76625698cabe0d6107be53 423 Gene3D G3DSA:1.10.246.90 261 385 6.8E-49 T 31-10-2018 N186_02900 33ca8e68bc76625698cabe0d6107be53 423 Gene3D G3DSA:1.10.287.660 148 260 9.8E-39 T 31-10-2018 IPR029012 Helix hairpin bin domain superfamily N186_02900 33ca8e68bc76625698cabe0d6107be53 423 SUPERFAMILY SSF89124 142 382 2.09E-79 T 31-10-2018 IPR036070 Nop domain superfamily N186_02900 33ca8e68bc76625698cabe0d6107be53 423 Pfam PF01798 snoRNA binding domain, fibrillarin 155 380 4.4E-73 T 31-10-2018 IPR002687 Nop domain N186_02900 33ca8e68bc76625698cabe0d6107be53 423 Gene3D G3DSA:3.30.420.220 3 142 2.4E-12 T 31-10-2018 N186_03060 82ada598eecf68601e6a1147eb346f85 92 Gene3D G3DSA:1.20.5.820 3 60 5.1E-10 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 N186_03060 82ada598eecf68601e6a1147eb346f85 92 SUPERFAMILY SSF103456 10 55 8.89E-9 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 N186_07995 789dc65619664d7c2627a1420eecb30f 374 Gene3D G3DSA:3.90.550.10 3 261 5.7E-48 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_07995 789dc65619664d7c2627a1420eecb30f 374 Pfam PF00535 Glycosyl transferase family 2 16 123 2.0E-26 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 N186_07995 789dc65619664d7c2627a1420eecb30f 374 SUPERFAMILY SSF53448 11 301 4.66E-51 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_04095 b876641094dc033fb36a3def3f36fb2d 283 SUPERFAMILY SSF52540 6 197 1.88E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04095 b876641094dc033fb36a3def3f36fb2d 283 Pfam PF00005 ABC transporter 6 144 2.0E-21 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_04095 b876641094dc033fb36a3def3f36fb2d 283 Gene3D G3DSA:3.40.50.300 2 246 4.8E-51 T 31-10-2018 N186_04095 b876641094dc033fb36a3def3f36fb2d 283 ProSitePatterns PS00211 ABC transporters family signature. 116 130 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_04095 b876641094dc033fb36a3def3f36fb2d 283 SMART SM00382 13 192 2.7E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00945 d1f5d52acb72dac918600bba38d44b98 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.1E-14 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_00945 d1f5d52acb72dac918600bba38d44b98 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.1E-14 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_00945 d1f5d52acb72dac918600bba38d44b98 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.1E-14 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_00945 d1f5d52acb72dac918600bba38d44b98 158 Gene3D G3DSA:3.30.70.920 54 151 3.9E-31 T 31-10-2018 N186_00945 d1f5d52acb72dac918600bba38d44b98 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 1.5E-15 T 31-10-2018 N186_00945 d1f5d52acb72dac918600bba38d44b98 158 SUPERFAMILY SSF54909 62 151 5.5E-21 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel N186_00945 d1f5d52acb72dac918600bba38d44b98 158 SUPERFAMILY SSF46785 1 62 2.31E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_00945 d1f5d52acb72dac918600bba38d44b98 158 Gene3D G3DSA:1.10.10.10 2 53 3.7E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_00945 d1f5d52acb72dac918600bba38d44b98 158 Pfam PF01037 Lrp/AsnC ligand binding domain 69 141 2.1E-21 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain N186_00945 d1f5d52acb72dac918600bba38d44b98 158 SMART SM00344 2 111 2.3E-46 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 Gene3D G3DSA:1.10.10.410 567 626 1.0E-11 T 31-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 174 188 - T 31-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 Pfam PF02934 GatB/GatE catalytic domain 7 444 9.0E-70 T 31-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 Pfam PF02938 GAD domain 296 389 7.4E-18 T 31-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 SUPERFAMILY SSF55931 379 452 1.96E-11 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 Gene3D G3DSA:1.10.150.380 452 547 4.3E-24 T 31-10-2018 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 Gene3D G3DSA:3.30.1360.30 271 403 6.2E-48 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 Pfam PF02637 GatB domain 484 625 5.8E-25 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 SMART SM00845 483 625 1.6E-30 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 4 628 7.8E-235 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 SUPERFAMILY SSF55931 2 291 3.34E-87 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 SUPERFAMILY SSF89095 484 625 1.18E-22 T 31-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 631 307.011 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 SUPERFAMILY SSF55261 275 403 8.34E-44 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 N186_02820 5a9f0cb221800fd7d397e494b7b89618 631 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 279 405 3.0E-28 T 31-10-2018 N186_07825 a8d56edc5c24d310955cff8304d9347a 289 Pfam PF00753 Metallo-beta-lactamase superfamily 36 113 3.3E-11 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_07825 a8d56edc5c24d310955cff8304d9347a 289 Gene3D G3DSA:3.60.15.10 2 282 1.3E-74 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_07825 a8d56edc5c24d310955cff8304d9347a 289 SUPERFAMILY SSF56281 16 259 1.57E-23 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_01885 0ca61e140837c9259e2aee9c459bc0f5 147 Gene3D G3DSA:2.40.50.140 7 124 2.3E-30 T 31-10-2018 N186_01885 0ca61e140837c9259e2aee9c459bc0f5 147 SUPERFAMILY SSF50249 6 127 1.41E-31 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_02115 38e101f509c9d8e9f77e8e287fab32ab 129 Pfam PF00410 Ribosomal protein S8 4 129 5.1E-25 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02115 38e101f509c9d8e9f77e8e287fab32ab 129 ProSitePatterns PS00053 Ribosomal protein S8 signature. 99 116 - T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02115 38e101f509c9d8e9f77e8e287fab32ab 129 Gene3D G3DSA:3.30.1370.30 1 68 6.0E-27 T 31-10-2018 N186_02115 38e101f509c9d8e9f77e8e287fab32ab 129 Gene3D G3DSA:3.30.1490.10 69 127 6.8E-27 T 31-10-2018 N186_02115 38e101f509c9d8e9f77e8e287fab32ab 129 SUPERFAMILY SSF56047 1 129 2.88E-38 T 31-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02115 38e101f509c9d8e9f77e8e287fab32ab 129 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 1 129 36.748 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01565 2c1bb32fad5c178f0fc6dbea406ca32d 291 SUPERFAMILY SSF55486 10 224 6.44E-7 T 31-10-2018 N186_01565 2c1bb32fad5c178f0fc6dbea406ca32d 291 Gene3D G3DSA:1.10.390.60 4 220 1.6E-6 T 31-10-2018 N186_07480 d60e778a2342336477e93dc894476738 697 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 12 231 1.2E-23 T 31-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 N186_07480 d60e778a2342336477e93dc894476738 697 Gene3D G3DSA:1.50.10.10 278 657 8.5E-128 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 N186_07480 d60e778a2342336477e93dc894476738 697 SUPERFAMILY SSF48208 238 675 1.81E-95 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 N186_07480 d60e778a2342336477e93dc894476738 697 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 283 668 8.2E-113 T 31-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 N186_07480 d60e778a2342336477e93dc894476738 697 PIRSF PIRSF036289 1 697 4.9E-162 T 31-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase N186_07480 d60e778a2342336477e93dc894476738 697 Gene3D G3DSA:2.70.98.40 2 236 3.4E-28 T 31-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily N186_07480 d60e778a2342336477e93dc894476738 697 SUPERFAMILY SSF74650 13 231 3.01E-25 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 N186_06885 6e104dcd50bf020cbe929e1e6b01d4c5 333 Pfam PF07690 Major Facilitator Superfamily 4 265 2.5E-9 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_06885 6e104dcd50bf020cbe929e1e6b01d4c5 333 SUPERFAMILY SSF103473 3 328 1.96E-20 T 31-10-2018 IPR036259 MFS transporter superfamily N186_06885 6e104dcd50bf020cbe929e1e6b01d4c5 333 Gene3D G3DSA:1.20.1250.20 158 333 9.1E-7 T 31-10-2018 N186_06885 6e104dcd50bf020cbe929e1e6b01d4c5 333 Gene3D G3DSA:1.20.1250.20 1 148 6.8E-11 T 31-10-2018 N186_08465 324b1366f5b1a5a25af376a3650b2019 463 SMART SM00481 152 215 6.4E-12 T 31-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal N186_08465 324b1366f5b1a5a25af376a3650b2019 463 Gene3D G3DSA:3.20.20.140 136 353 6.1E-55 T 31-10-2018 N186_08465 324b1366f5b1a5a25af376a3650b2019 463 SUPERFAMILY SSF89550 148 352 5.23E-38 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 N186_08465 324b1366f5b1a5a25af376a3650b2019 463 Pfam PF02811 PHP domain 153 357 2.7E-6 T 31-10-2018 IPR004013 PHP domain GO:0003824 N186_02095 04131e7dcd8b125ce984dabf42f4873a 202 SUPERFAMILY SSF54768 40 111 7.85E-19 T 31-10-2018 N186_02095 04131e7dcd8b125ce984dabf42f4873a 202 ProSitePatterns PS00585 Ribosomal protein S5 signature. 63 95 - T 31-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site N186_02095 04131e7dcd8b125ce984dabf42f4873a 202 Pfam PF03719 Ribosomal protein S5, C-terminal domain 131 196 1.1E-24 T 31-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 N186_02095 04131e7dcd8b125ce984dabf42f4873a 202 SUPERFAMILY SSF54211 124 198 3.03E-22 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_02095 04131e7dcd8b125ce984dabf42f4873a 202 Gene3D G3DSA:3.30.230.10 109 202 5.1E-35 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup N186_02095 04131e7dcd8b125ce984dabf42f4873a 202 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 1 198 47.583 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02095 04131e7dcd8b125ce984dabf42f4873a 202 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 3 196 1.6E-95 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02095 04131e7dcd8b125ce984dabf42f4873a 202 Pfam PF00333 Ribosomal protein S5, N-terminal domain 46 110 2.6E-22 T 31-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 N186_02095 04131e7dcd8b125ce984dabf42f4873a 202 Gene3D G3DSA:3.30.160.770 4 108 1.2E-37 T 31-10-2018 N186_07470 0ffee149f15be46e24f022e7564589c1 337 SUPERFAMILY SSF159071 248 335 2.35E-17 T 31-10-2018 N186_07470 0ffee149f15be46e24f022e7564589c1 337 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 9 76 9.6E-21 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal N186_07470 0ffee149f15be46e24f022e7564589c1 337 SUPERFAMILY SSF46785 4 88 2.96E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_07470 0ffee149f15be46e24f022e7564589c1 337 Gene3D G3DSA:1.10.10.10 3 104 2.3E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_07470 0ffee149f15be46e24f022e7564589c1 337 Pfam PF11495 Archaeal transcriptional regulator TrmB 114 336 2.6E-39 T 31-10-2018 IPR021586 Transcription regulator TrmB, C-terminal N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 Pfam PF03465 eRF1 domain 3 273 408 1.7E-35 T 31-10-2018 IPR005142 eRF1 domain 3 N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 SUPERFAMILY SSF55315 270 409 1.71E-38 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 Gene3D G3DSA:3.30.960.10 1 135 7.8E-50 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 Pfam PF03464 eRF1 domain 2 140 270 6.6E-43 T 31-10-2018 IPR005141 eRF1 domain 2 N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 Gene3D G3DSA:3.30.1330.30 271 410 1.3E-43 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 SUPERFAMILY SSF55481 3 135 1.31E-46 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 6 407 1.9E-174 T 31-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 17 409 43.706 T 31-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 SMART SM01194 1 135 3.9E-41 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 Pfam PF03463 eRF1 domain 1 12 133 3.3E-10 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 SUPERFAMILY SSF53137 138 268 1.31E-39 T 31-10-2018 N186_03555 76c5c5e504d98af8e0905e72c73c909c 410 Gene3D G3DSA:3.30.420.60 137 269 2.0E-47 T 31-10-2018 N186_05630 7c951e0e06d10960473a9c9f16eb0aeb 266 SUPERFAMILY SSF51658 16 259 4.98E-59 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily N186_05630 7c951e0e06d10960473a9c9f16eb0aeb 266 Pfam PF01261 Xylose isomerase-like TIM barrel 23 213 7.4E-32 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain N186_05630 7c951e0e06d10960473a9c9f16eb0aeb 266 Gene3D G3DSA:3.20.20.150 4 265 6.1E-62 T 31-10-2018 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 Pfam PF00113 Enolase, C-terminal TIM barrel domain 146 428 1.2E-123 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 Pfam PF03952 Enolase, N-terminal domain 11 140 9.9E-54 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 11 431 7.0E-192 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 SMART SM01192 145 431 1.7E-194 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 SUPERFAMILY SSF51604 144 431 8.3E-120 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 SMART SM01193 11 140 1.1E-85 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 PRINTS PR00148 Enolase signature 167 180 1.3E-44 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 PRINTS PR00148 Enolase signature 369 386 1.3E-44 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 PRINTS PR00148 Enolase signature 340 354 1.3E-44 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 PRINTS PR00148 Enolase signature 317 328 1.3E-44 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 PRINTS PR00148 Enolase signature 44 58 1.3E-44 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 PRINTS PR00148 Enolase signature 113 129 1.3E-44 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 SUPERFAMILY SSF54826 11 145 2.86E-51 T 31-10-2018 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 Gene3D G3DSA:3.20.20.120 134 434 4.9E-130 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 PIRSF PIRSF001400 7 431 3.2E-190 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 Hamap MF_00318 Enolase [eno]. 9 417 45.315 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 ProSitePatterns PS00164 Enolase signature. 340 353 - T 31-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_01480 42f4a3ed4ea9b30f74ad517912244154 434 Gene3D G3DSA:3.30.390.10 10 132 1.1E-52 T 31-10-2018 IPR029017 Enolase-like, N-terminal N186_00110 923a930c5834ad4e2b28293edcefee69 111 Pfam PF03551 Transcriptional regulator PadR-like family 26 92 1.0E-9 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal N186_00110 923a930c5834ad4e2b28293edcefee69 111 SUPERFAMILY SSF46785 20 100 1.16E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_00110 923a930c5834ad4e2b28293edcefee69 111 Gene3D G3DSA:1.10.10.10 5 109 7.3E-16 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 145 2.6E-45 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 304 1.8E-117 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 48 62 9.6E-27 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 9.6E-27 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 121 135 9.6E-27 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 219 229 9.6E-27 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 81 94 9.6E-27 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 2.5E-28 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 2.5E-28 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 2.5E-28 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 2.5E-28 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 SUPERFAMILY SSF53671 2 304 1.7E-98 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 Gene3D G3DSA:3.40.50.1370 4 134 1.2E-111 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 302 4.4E-53 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 305 73.59 T 31-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_03065 b935b1fedc8a1550d15e52affc0b540e 319 Gene3D G3DSA:3.40.50.1370 135 300 1.2E-111 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 N186_02330 239b4b27fc9d59243006a72508e6e2ff 400 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 24 394 4.1E-148 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02330 239b4b27fc9d59243006a72508e6e2ff 400 Gene3D G3DSA:1.10.150.390 343 389 3.2E-21 T 31-10-2018 N186_02330 239b4b27fc9d59243006a72508e6e2ff 400 SUPERFAMILY SSF64484 37 396 1.26E-97 T 31-10-2018 N186_02330 239b4b27fc9d59243006a72508e6e2ff 400 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 9 396 40.316 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02330 239b4b27fc9d59243006a72508e6e2ff 400 Pfam PF04998 RNA polymerase Rpb1, domain 5 45 340 1.3E-55 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_07015 de157ba43fcf94147b08869dd7ba5ef1 552 SUPERFAMILY SSF52317 306 546 1.33E-70 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like N186_07015 de157ba43fcf94147b08869dd7ba5ef1 552 Gene3D G3DSA:3.40.50.880 303 548 3.0E-89 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like N186_07015 de157ba43fcf94147b08869dd7ba5ef1 552 SUPERFAMILY SSF52540 3 282 9.62E-106 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07015 de157ba43fcf94147b08869dd7ba5ef1 552 Pfam PF00117 Glutamine amidotransferase class-I 318 545 6.4E-47 T 31-10-2018 IPR017926 Glutamine amidotransferase N186_07015 de157ba43fcf94147b08869dd7ba5ef1 552 Pfam PF06418 CTP synthase N-terminus 4 281 1.8E-113 T 31-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 N186_07015 de157ba43fcf94147b08869dd7ba5ef1 552 Gene3D G3DSA:3.40.50.300 1 302 6.2E-126 T 31-10-2018 N186_07015 de157ba43fcf94147b08869dd7ba5ef1 552 TIGRFAM TIGR00337 PyrG: CTP synthase 3 545 4.0E-207 T 31-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 N186_07780 0b1f4904fad19eb43f5bca6210458af9 279 SUPERFAMILY SSF161098 47 268 5.89E-38 T 31-10-2018 IPR035906 MetI-like superfamily N186_07780 0b1f4904fad19eb43f5bca6210458af9 279 Gene3D G3DSA:1.10.3720.10 43 276 1.1E-39 T 31-10-2018 IPR035906 MetI-like superfamily N186_07780 0b1f4904fad19eb43f5bca6210458af9 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 269 1.4E-6 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_00835 3875b6398ff175d9516ba7b61942556d 365 SUPERFAMILY SSF101821 76 185 2.29E-31 T 31-10-2018 N186_00835 3875b6398ff175d9516ba7b61942556d 365 SUPERFAMILY SSF53187 11 360 2.54E-65 T 31-10-2018 N186_00835 3875b6398ff175d9516ba7b61942556d 365 Gene3D G3DSA:2.40.30.40 75 167 1.5E-120 T 31-10-2018 IPR023367 Peptidase M42, domain 2 N186_00835 3875b6398ff175d9516ba7b61942556d 365 Pfam PF05343 M42 glutamyl aminopeptidase 51 346 4.2E-98 T 31-10-2018 IPR008007 Peptidase M42 N186_00835 3875b6398ff175d9516ba7b61942556d 365 PIRSF PIRSF001123 7 365 3.0E-125 T 31-10-2018 IPR008007 Peptidase M42 N186_00835 3875b6398ff175d9516ba7b61942556d 365 Gene3D G3DSA:3.40.630.10 14 346 1.5E-120 T 31-10-2018 N186_06515 0961637ea9595bf23321f2fea76233ab 329 SUPERFAMILY SSF117892 79 207 5.1E-10 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily N186_06515 0961637ea9595bf23321f2fea76233ab 329 Pfam PF13240 zinc-ribbon domain 306 328 2.3E-8 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 N186_06515 0961637ea9595bf23321f2fea76233ab 329 Pfam PF10571 Uncharacterised protein family UPF0547 277 302 8.9E-11 T 31-10-2018 IPR018886 Uncharacterised domain UPF0547 N186_06515 0961637ea9595bf23321f2fea76233ab 329 Pfam PF13421 SPFH domain-Band 7 family 16 206 6.7E-32 T 31-10-2018 IPR033880 SPFH domain, YdjI-like N186_08575 a61bea2fd1e13c7242ae0aa5ce96c3fc 282 Pfam PF01061 ABC-2 type transporter 20 227 1.0E-10 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 14 561 5.9E-125 T 31-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 SUPERFAMILY SSF52009 129 248 3.14E-19 T 31-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 450 468 - T 31-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 Pfam PF00391 PEP-utilising enzyme, mobile domain 156 226 1.7E-10 T 31-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 Gene3D G3DSA:3.20.20.60 236 578 4.3E-92 T 31-10-2018 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 SUPERFAMILY SSF47831 41 146 6.02E-14 T 31-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 Gene3D G3DSA:1.10.274.10 31 149 2.3E-41 T 31-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 257 543 4.0E-81 T 31-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 Gene3D G3DSA:3.50.30.10 14 233 2.3E-41 T 31-10-2018 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 467 482 5.2E-19 T 31-10-2018 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 5.2E-19 T 31-10-2018 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 502 514 5.2E-19 T 31-10-2018 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 450 465 5.2E-19 T 31-10-2018 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 PIRSF PIRSF000732 7 577 2.1E-154 T 31-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 SUPERFAMILY SSF51621 255 549 8.64E-80 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 N186_06665 f8d740e324a29b6cca91c34803fcd526 581 Pfam PF05524 PEP-utilising enzyme, N-terminal 13 122 1.3E-15 T 31-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 N186_01430 f349e11285913fb334f281e9d55336ce 85 Gene3D G3DSA:1.10.1220.10 33 69 2.9E-9 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 N186_01430 f349e11285913fb334f281e9d55336ce 85 SUPERFAMILY SSF47598 27 70 1.22E-10 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 N186_01430 f349e11285913fb334f281e9d55336ce 85 Pfam PF01402 Ribbon-helix-helix protein, copG family 29 66 1.5E-8 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 N186_05620 248c5cf3749b56d8b48cdb35d3d084e8 158 SUPERFAMILY SSF55729 6 150 1.36E-33 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase N186_05620 248c5cf3749b56d8b48cdb35d3d084e8 158 Gene3D G3DSA:3.40.630.30 4 155 4.7E-39 T 31-10-2018 N186_05620 248c5cf3749b56d8b48cdb35d3d084e8 158 Pfam PF00583 Acetyltransferase (GNAT) family 38 126 5.4E-20 T 31-10-2018 IPR000182 GNAT domain N186_05620 248c5cf3749b56d8b48cdb35d3d084e8 158 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 19 144 1.4E-28 T 31-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 N186_02620 cc434935d1a5923219b14a68387da2e1 87 Pfam PF01247 Ribosomal protein L35Ae 3 86 2.9E-14 T 31-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02620 cc434935d1a5923219b14a68387da2e1 87 Gene3D G3DSA:2.40.10.190 1 87 5.5E-20 T 31-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02620 cc434935d1a5923219b14a68387da2e1 87 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 5 86 6.0E-13 T 31-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02620 cc434935d1a5923219b14a68387da2e1 87 SUPERFAMILY SSF50447 2 86 5.65E-20 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_02620 cc434935d1a5923219b14a68387da2e1 87 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 3 87 22.357 T 31-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_08675 bcaaac0c5347d3856f4c69f51651581d 456 Gene3D G3DSA:1.10.10.10 232 298 4.4E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_08675 bcaaac0c5347d3856f4c69f51651581d 456 Gene3D G3DSA:3.40.50.300 3 167 1.5E-24 T 31-10-2018 N186_08675 bcaaac0c5347d3856f4c69f51651581d 456 Pfam PF01637 ATPase domain predominantly from Archaea 5 201 3.7E-18 T 31-10-2018 IPR011579 ATPase domain GO:0005524 N186_08675 bcaaac0c5347d3856f4c69f51651581d 456 SUPERFAMILY SSF46785 232 343 1.17E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_08675 bcaaac0c5347d3856f4c69f51651581d 456 Pfam PF03008 Archaea bacterial proteins of unknown function 306 401 1.1E-26 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal N186_08675 bcaaac0c5347d3856f4c69f51651581d 456 SUPERFAMILY SSF52540 4 211 8.51E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07420 210fda759768eaa7f59f9b70cabcb011 180 Pfam PF04073 Aminoacyl-tRNA editing domain 44 159 1.6E-28 T 31-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 N186_07420 210fda759768eaa7f59f9b70cabcb011 180 Gene3D G3DSA:3.90.960.10 22 165 1.7E-37 T 31-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 N186_07420 210fda759768eaa7f59f9b70cabcb011 180 SUPERFAMILY SSF55826 22 164 1.96E-36 T 31-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 N186_04575 901dddc7b1c36197d0e84412153efaad 130 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 12 50 1.1E-12 T 31-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 N186_03845 f5af88b63a337397bde298cbd0796b22 382 Pfam PF01472 PUA domain 88 157 2.3E-10 T 31-10-2018 IPR002478 PUA domain GO:0003723 N186_03845 f5af88b63a337397bde298cbd0796b22 382 SUPERFAMILY SSF53335 135 382 1.88E-52 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_03845 f5af88b63a337397bde298cbd0796b22 382 SUPERFAMILY SSF88697 87 158 9.39E-14 T 31-10-2018 IPR015947 PUA-like superfamily N186_03845 f5af88b63a337397bde298cbd0796b22 382 Gene3D G3DSA:3.30.70.3130 1 86 1.1E-6 T 31-10-2018 N186_03845 f5af88b63a337397bde298cbd0796b22 382 Pfam PF01189 16S rRNA methyltransferase RsmB/F 189 379 6.9E-45 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 N186_03845 f5af88b63a337397bde298cbd0796b22 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 314 330 6.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase N186_03845 f5af88b63a337397bde298cbd0796b22 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 267 279 6.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase N186_03845 f5af88b63a337397bde298cbd0796b22 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 364 381 6.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase N186_03845 f5af88b63a337397bde298cbd0796b22 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 199 209 6.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase N186_03845 f5af88b63a337397bde298cbd0796b22 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 170 184 6.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase N186_03845 f5af88b63a337397bde298cbd0796b22 382 Gene3D G3DSA:3.40.50.150 186 382 3.2E-53 T 31-10-2018 N186_03845 f5af88b63a337397bde298cbd0796b22 382 SMART SM00359 87 160 3.9E-5 T 31-10-2018 IPR002478 PUA domain GO:0003723 N186_03845 f5af88b63a337397bde298cbd0796b22 382 Gene3D G3DSA:2.30.130.10 87 162 9.3E-14 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 N186_04500 c623ce6a6c344f90f261e904676f9164 461 SUPERFAMILY SSF50249 68 167 2.48E-12 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_04500 c623ce6a6c344f90f261e904676f9164 461 Gene3D G3DSA:2.40.50.140 65 169 9.2E-14 T 31-10-2018 N186_04500 c623ce6a6c344f90f261e904676f9164 461 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 5 55 3.9E-5 T 31-10-2018 IPR018716 Protein of unknown function DUF2240 N186_01435 0988967c84b22dbbf12a3a9b87ec0f7b 108 Gene3D G3DSA:2.40.50.140 1 108 1.5E-40 T 31-10-2018 N186_01435 0988967c84b22dbbf12a3a9b87ec0f7b 108 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 2 107 3.2E-43 T 31-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 N186_01435 0988967c84b22dbbf12a3a9b87ec0f7b 108 SUPERFAMILY SSF50249 7 107 1.32E-36 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_01435 0988967c84b22dbbf12a3a9b87ec0f7b 108 Pfam PF01588 Putative tRNA binding domain 14 106 1.6E-31 T 31-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 N186_01830 1969ceb13159c5d5cadb40aa5479ab4e 443 Gene3D G3DSA:3.40.50.300 94 298 1.5E-28 T 31-10-2018 N186_01830 1969ceb13159c5d5cadb40aa5479ab4e 443 SUPERFAMILY SSF52540 107 264 2.1E-13 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01830 1969ceb13159c5d5cadb40aa5479ab4e 443 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 113 291 5.1E-38 T 31-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain N186_09665 c6ff2e392638b6dcfc2173c5d65f9707 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 249 3.6E-6 T 31-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal N186_09665 c6ff2e392638b6dcfc2173c5d65f9707 250 SUPERFAMILY SSF52540 5 248 5.0E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09665 c6ff2e392638b6dcfc2173c5d65f9707 250 SMART SM00382 30 227 3.3E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_09665 c6ff2e392638b6dcfc2173c5d65f9707 250 Pfam PF00005 ABC transporter 22 178 2.5E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09665 c6ff2e392638b6dcfc2173c5d65f9707 250 Gene3D G3DSA:3.40.50.300 2 250 2.2E-59 T 31-10-2018 N186_00720 8e875aeee20120ef13768279aa04f409 205 Pfam PF06168 Protein of unknown function (DUF981) 8 188 1.6E-52 T 31-10-2018 IPR009324 Protein of unknown function DUF981 N186_04185 ceaaf17b59200723edf77037b60ad40c 262 Gene3D G3DSA:3.40.50.300 6 258 1.0E-55 T 31-10-2018 N186_04185 ceaaf17b59200723edf77037b60ad40c 262 SUPERFAMILY SSF52540 13 254 9.1E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04185 ceaaf17b59200723edf77037b60ad40c 262 Pfam PF03029 Conserved hypothetical ATP binding protein 16 256 2.6E-47 T 31-10-2018 IPR004130 GPN-loop GTPase N186_04185 ceaaf17b59200723edf77037b60ad40c 262 SMART SM00382 10 177 0.0016 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01610 ce8458cb9ab5cd052f564c8548eb9bb6 524 Gene3D G3DSA:3.40.50.300 107 335 7.3E-31 T 31-10-2018 N186_01610 ce8458cb9ab5cd052f564c8548eb9bb6 524 SUPERFAMILY SSF50447 341 434 8.44E-19 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_01610 ce8458cb9ab5cd052f564c8548eb9bb6 524 Gene3D G3DSA:2.40.30.10 436 522 1.9E-5 T 31-10-2018 N186_01610 ce8458cb9ab5cd052f564c8548eb9bb6 524 Pfam PF03144 Elongation factor Tu domain 2 360 430 9.7E-9 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 N186_01610 ce8458cb9ab5cd052f564c8548eb9bb6 524 Pfam PF00009 Elongation factor Tu GTP binding domain 115 329 6.4E-20 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_01610 ce8458cb9ab5cd052f564c8548eb9bb6 524 Gene3D G3DSA:2.40.30.10 341 435 3.9E-20 T 31-10-2018 N186_01610 ce8458cb9ab5cd052f564c8548eb9bb6 524 SUPERFAMILY SSF50465 435 523 6.37E-17 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal N186_01610 ce8458cb9ab5cd052f564c8548eb9bb6 524 SUPERFAMILY SSF52540 114 360 1.12E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 Gene3D G3DSA:3.40.50.300 30 214 9.9E-67 T 31-10-2018 N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 Pfam PF13401 AAA domain 61 186 9.0E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 15 392 3.3E-72 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 Gene3D G3DSA:1.10.8.60 19 292 9.9E-67 T 31-10-2018 N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 SUPERFAMILY SSF46785 307 398 2.18E-20 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 Gene3D G3DSA:1.10.10.10 303 424 4.7E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 Pfam PF09079 CDC6, C terminal winged helix domain 320 394 1.4E-10 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 Hamap MF_01407 ORC1-type DNA replication protein. 7 404 24.332 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 SUPERFAMILY SSF52540 14 296 1.65E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02230 093a9ee9685047450cdf00c042c0bbd4 436 SMART SM01074 320 404 2.1E-13 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 N186_05865 64f8b36c6b9cc03bbc108ff98ce166b0 382 Gene3D G3DSA:1.10.8.60 14 276 5.9E-51 T 31-10-2018 N186_05865 64f8b36c6b9cc03bbc108ff98ce166b0 382 SMART SM00382 48 217 9.1E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_05865 64f8b36c6b9cc03bbc108ff98ce166b0 382 SUPERFAMILY SSF46785 291 380 1.52E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_05865 64f8b36c6b9cc03bbc108ff98ce166b0 382 Pfam PF13401 AAA domain 54 178 1.5E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_05865 64f8b36c6b9cc03bbc108ff98ce166b0 382 Gene3D G3DSA:3.40.50.300 25 204 5.9E-51 T 31-10-2018 N186_05865 64f8b36c6b9cc03bbc108ff98ce166b0 382 SUPERFAMILY SSF52540 9 281 3.23E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05865 64f8b36c6b9cc03bbc108ff98ce166b0 382 Hamap MF_01407 ORC1-type DNA replication protein. 2 380 18.747 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea N186_05865 64f8b36c6b9cc03bbc108ff98ce166b0 382 Gene3D G3DSA:1.10.10.10 288 362 1.4E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_00325 e0a8f6c9ec32885b420b42e5a05c07a3 318 Gene3D G3DSA:3.40.50.300 3 318 2.0E-82 T 31-10-2018 N186_00325 e0a8f6c9ec32885b420b42e5a05c07a3 318 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 316 1.8E-17 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_00325 e0a8f6c9ec32885b420b42e5a05c07a3 318 Pfam PF00005 ABC transporter 28 182 8.4E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00325 e0a8f6c9ec32885b420b42e5a05c07a3 318 SMART SM00382 37 232 1.9E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00325 e0a8f6c9ec32885b420b42e5a05c07a3 318 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 297 5.0E-16 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_00325 e0a8f6c9ec32885b420b42e5a05c07a3 318 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_00325 e0a8f6c9ec32885b420b42e5a05c07a3 318 SUPERFAMILY SSF52540 5 244 1.15E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00325 e0a8f6c9ec32885b420b42e5a05c07a3 318 PRINTS PR01868 ABC transporter family E signature 42 67 4.4E-5 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 N186_00325 e0a8f6c9ec32885b420b42e5a05c07a3 318 PRINTS PR01868 ABC transporter family E signature 73 89 4.4E-5 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 N186_06630 72fce5cfd464d91f18d62d2cac779080 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 143 162 4.9E-19 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06630 72fce5cfd464d91f18d62d2cac779080 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 245 269 4.9E-19 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06630 72fce5cfd464d91f18d62d2cac779080 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 386 412 4.9E-19 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06630 72fce5cfd464d91f18d62d2cac779080 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 333 352 4.9E-19 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06630 72fce5cfd464d91f18d62d2cac779080 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 173 197 4.9E-19 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06630 72fce5cfd464d91f18d62d2cac779080 501 Pfam PF00361 Proton-conducting membrane transporter 137 417 9.6E-58 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06565 0f27ed0cdfaea6eab7697ced583c5668 324 Pfam PF00146 NADH dehydrogenase 18 317 4.4E-70 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_00345 7d44e543387f450efdf643c15717aadf 650 Gene3D G3DSA:3.40.190.10 52 579 9.7E-173 T 31-10-2018 N186_00345 7d44e543387f450efdf643c15717aadf 650 SUPERFAMILY SSF53850 45 579 3.53E-98 T 31-10-2018 N186_00345 7d44e543387f450efdf643c15717aadf 650 Gene3D G3DSA:3.90.76.10 59 222 9.7E-173 T 31-10-2018 N186_00345 7d44e543387f450efdf643c15717aadf 650 Gene3D G3DSA:3.10.105.10 315 551 9.7E-173 T 31-10-2018 N186_00345 7d44e543387f450efdf643c15717aadf 650 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 96 492 3.9E-62 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain N186_02890 2b9225b8fd7df2f93aca34f277b39a77 191 Pfam PF00382 Transcription factor TFIIB repeat 132 173 1.8E-4 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 N186_02890 2b9225b8fd7df2f93aca34f277b39a77 191 Pfam PF00382 Transcription factor TFIIB repeat 7 75 1.4E-10 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 N186_02890 2b9225b8fd7df2f93aca34f277b39a77 191 SUPERFAMILY SSF47954 7 84 3.4E-14 T 31-10-2018 IPR036915 Cyclin-like superfamily N186_02890 2b9225b8fd7df2f93aca34f277b39a77 191 PRINTS PR00685 Transcription initiation factor IIB signature 71 86 7.4E-5 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_02890 2b9225b8fd7df2f93aca34f277b39a77 191 PRINTS PR00685 Transcription initiation factor IIB signature 137 153 7.4E-5 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_02890 2b9225b8fd7df2f93aca34f277b39a77 191 PRINTS PR00685 Transcription initiation factor IIB signature 169 183 7.4E-5 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 N186_02890 2b9225b8fd7df2f93aca34f277b39a77 191 Gene3D G3DSA:1.10.472.10 3 86 5.8E-17 T 31-10-2018 N186_02890 2b9225b8fd7df2f93aca34f277b39a77 191 Gene3D G3DSA:1.10.472.10 98 189 1.1E-10 T 31-10-2018 N186_02890 2b9225b8fd7df2f93aca34f277b39a77 191 SUPERFAMILY SSF47954 97 188 5.27E-12 T 31-10-2018 IPR036915 Cyclin-like superfamily N186_01550 0379ab92c67a6a0bc568be2ad9f79346 230 SUPERFAMILY SSF53167 2 226 1.22E-59 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 N186_01550 0379ab92c67a6a0bc568be2ad9f79346 230 Gene3D G3DSA:3.40.50.1580 1 230 9.9E-60 T 31-10-2018 N186_01550 0379ab92c67a6a0bc568be2ad9f79346 230 Pfam PF01048 Phosphorylase superfamily 12 202 4.9E-36 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 N186_04890 15396f0d0114c4ebc4f893b75ba305ec 156 Pfam PF01381 Helix-turn-helix 76 128 5.5E-12 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 N186_04890 15396f0d0114c4ebc4f893b75ba305ec 156 SMART SM00530 75 130 2.6E-9 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 N186_04890 15396f0d0114c4ebc4f893b75ba305ec 156 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 3 155 4.1E-38 T 31-10-2018 IPR004451 Conserved hypothetical protein CHP00270 N186_04890 15396f0d0114c4ebc4f893b75ba305ec 156 SUPERFAMILY SSF47413 69 136 1.18E-12 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 N186_04890 15396f0d0114c4ebc4f893b75ba305ec 156 Gene3D G3DSA:1.10.260.40 63 156 1.4E-18 T 31-10-2018 N186_09285 f5bef30a757a222c52f9eb8a15f31867 291 SUPERFAMILY SSF52096 53 240 4.8E-28 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily N186_09285 f5bef30a757a222c52f9eb8a15f31867 291 Gene3D G3DSA:3.90.226.10 62 254 8.9E-23 T 31-10-2018 N186_09285 f5bef30a757a222c52f9eb8a15f31867 291 Pfam PF01972 Serine dehydrogenase proteinase 5 274 3.4E-120 T 31-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 69 131 2.9E-12 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 Gene3D G3DSA:2.40.50.140 69 132 9.2E-28 T 31-10-2018 N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 PIRSF PIRSF003025 1 132 1.6E-48 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 2 130 3.4E-45 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 SMART SM01376 69 131 2.0E-23 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 Gene3D G3DSA:2.30.30.30 1 68 9.9E-31 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 34 41 - T 31-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 SUPERFAMILY SSF50104 1 77 4.81E-22 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 2 130 32.806 T 31-10-2018 IPR022847 Translation elongation factor IF5A, archaeal N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 8 39 1.2E-6 T 31-10-2018 IPR013185 Translation elongation factor, KOW-like N186_03075 da6b1e9f795238cb6bda6b1c21b4ee74 132 SUPERFAMILY SSF50249 70 130 2.01E-13 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_07135 1f8c427bfd90be4753369e40267a3f5c 216 SUPERFAMILY SSF51735 1 127 2.03E-30 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_07135 1f8c427bfd90be4753369e40267a3f5c 216 SUPERFAMILY SSF116726 135 211 1.57E-13 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 N186_07135 1f8c427bfd90be4753369e40267a3f5c 216 Gene3D G3DSA:3.40.50.720 1 139 2.4E-34 T 31-10-2018 N186_07135 1f8c427bfd90be4753369e40267a3f5c 216 Pfam PF02080 TrkA-C domain 146 210 1.8E-12 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 N186_07135 1f8c427bfd90be4753369e40267a3f5c 216 Pfam PF02254 TrkA-N domain 3 118 7.7E-29 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 N186_07135 1f8c427bfd90be4753369e40267a3f5c 216 Gene3D G3DSA:3.30.70.1450 144 214 1.9E-12 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 N186_04545 9a621603d5604f3c5a9f88355ad52d4c 269 Pfam PF00575 S1 RNA binding domain 13 86 1.7E-11 T 31-10-2018 IPR003029 S1 domain GO:0003676 N186_04545 9a621603d5604f3c5a9f88355ad52d4c 269 Gene3D G3DSA:2.40.50.140 3 87 8.6E-27 T 31-10-2018 N186_04545 9a621603d5604f3c5a9f88355ad52d4c 269 SUPERFAMILY SSF110993 180 259 3.4E-16 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 N186_04545 9a621603d5604f3c5a9f88355ad52d4c 269 SUPERFAMILY SSF50249 12 90 1.17E-17 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_04545 9a621603d5604f3c5a9f88355ad52d4c 269 Gene3D G3DSA:1.10.150.190 88 177 3.9E-31 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 N186_04545 9a621603d5604f3c5a9f88355ad52d4c 269 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 124 234 9.8E-23 T 31-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 N186_04545 9a621603d5604f3c5a9f88355ad52d4c 269 SUPERFAMILY SSF116742 88 178 5.89E-25 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 N186_04545 9a621603d5604f3c5a9f88355ad52d4c 269 Gene3D G3DSA:3.30.70.1130 178 265 4.0E-21 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 N186_04545 9a621603d5604f3c5a9f88355ad52d4c 269 SMART SM00316 13 86 4.1E-14 T 31-10-2018 IPR022967 RNA-binding domain, S1 N186_05670 458d8916098cc229ac6a1ddfd31ad61d 383 Gene3D G3DSA:3.90.550.10 3 266 2.5E-67 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_05670 458d8916098cc229ac6a1ddfd31ad61d 383 Pfam PF00483 Nucleotidyl transferase 5 253 4.8E-39 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 N186_05670 458d8916098cc229ac6a1ddfd31ad61d 383 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 296 324 - T 31-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 N186_05670 458d8916098cc229ac6a1ddfd31ad61d 383 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 306 334 0.001 T 31-10-2018 IPR001451 Hexapeptide repeat N186_05670 458d8916098cc229ac6a1ddfd31ad61d 383 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 344 373 2.3E-5 T 31-10-2018 IPR001451 Hexapeptide repeat N186_05670 458d8916098cc229ac6a1ddfd31ad61d 383 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 273 303 4.0E-5 T 31-10-2018 IPR001451 Hexapeptide repeat N186_05670 458d8916098cc229ac6a1ddfd31ad61d 383 SUPERFAMILY SSF51161 229 379 4.12E-23 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily N186_05670 458d8916098cc229ac6a1ddfd31ad61d 383 SUPERFAMILY SSF53448 2 367 2.28E-63 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_05670 458d8916098cc229ac6a1ddfd31ad61d 383 Gene3D G3DSA:2.160.10.10 267 382 6.7E-19 T 31-10-2018 N186_06100 eab6420cf86538bb12ab33116dad423c 227 PIRSF PIRSF014439 1 227 1.1E-40 T 31-10-2018 IPR016619 Uncharacterised conserved protein UCP014439, ACT N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 Gene3D G3DSA:1.10.1510.30 190 278 1.6E-103 T 31-10-2018 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 PIRSF PIRSF037016 12 54 31.0 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 PIRSF PIRSF037016 48 417 1.0E-51 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 PIRSF PIRSF037016 414 444 0.054 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 Gene3D G3DSA:3.30.2350.20 147 434 1.6E-103 T 31-10-2018 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 15 435 9.1E-124 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 16 440 26.836 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 16 437 1.1E-71 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 Gene3D G3DSA:3.30.70.3160 59 146 1.6E-103 T 31-10-2018 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 97 110 - T 31-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 N186_04720 5f5c0b1e4464e5023e986745a6da1fff 446 SUPERFAMILY SSF55120 15 437 1.87E-72 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 N186_00790 6c8b35d563d14ce1941bf33a231424fb 247 Pfam PF04126 Cyclophilin-like 13 114 8.4E-25 T 31-10-2018 IPR025658 Cyclophilin TM1367-like domain N186_00790 6c8b35d563d14ce1941bf33a231424fb 247 SUPERFAMILY SSF50891 28 116 4.93E-17 T 31-10-2018 IPR029000 Cyclophilin-like domain superfamily N186_00790 6c8b35d563d14ce1941bf33a231424fb 247 Gene3D G3DSA:2.40.100.20 2 118 1.4E-19 T 31-10-2018 N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 4 426 29.571 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 SUPERFAMILY SSF52954 332 425 1.96E-18 T 31-10-2018 N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 Gene3D G3DSA:3.40.50.800 332 428 8.9E-21 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 18 379 24.091 T 31-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 Pfam PF03129 Anticodon binding domain 335 426 7.1E-16 T 31-10-2018 IPR004154 Anticodon-binding N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 Pfam PF13393 Histidyl-tRNA synthetase 11 317 9.1E-61 T 31-10-2018 N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 413 2.5E-122 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 PIRSF PIRSF001549 3 428 2.1E-126 T 31-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 Gene3D G3DSA:3.30.930.10 4 324 6.8E-100 T 31-10-2018 N186_04620 a3af449ef3346eaf8418bc7d0f27080f 429 SUPERFAMILY SSF55681 7 321 1.93E-79 T 31-10-2018 N186_04715 e8df6d83b4a37f69a0b9696940a41fa7 120 Gene3D G3DSA:3.40.1490.10 1 120 3.5E-45 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 N186_04715 e8df6d83b4a37f69a0b9696940a41fa7 120 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 6 120 27.785 T 31-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 N186_04715 e8df6d83b4a37f69a0b9696940a41fa7 120 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 6 120 8.4E-46 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 N186_04715 e8df6d83b4a37f69a0b9696940a41fa7 120 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 6 120 1.6E-43 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 N186_04715 e8df6d83b4a37f69a0b9696940a41fa7 120 SUPERFAMILY SSF102462 5 120 2.09E-42 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 SUPERFAMILY SSF51445 4 319 1.47E-100 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 320 578 3.1E-45 T 31-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 Gene3D G3DSA:2.60.40.10 581 699 2.8E-42 T 31-10-2018 IPR013783 Immunoglobulin-like fold N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 SMART SM01217 611 680 7.7E-25 T 31-10-2018 IPR026891 Fibronectin type III-like domain N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 Gene3D G3DSA:3.20.20.300 4 295 6.6E-123 T 31-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 30 288 4.1E-63 T 31-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 SUPERFAMILY SSF52279 320 581 5.49E-46 T 31-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 222 239 - T 31-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 PRINTS PR00133 Glycosyl hydrolase family 3 signature 48 64 1.1E-37 T 31-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 PRINTS PR00133 Glycosyl hydrolase family 3 signature 222 240 1.1E-37 T 31-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 PRINTS PR00133 Glycosyl hydrolase family 3 signature 121 137 1.1E-37 T 31-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 PRINTS PR00133 Glycosyl hydrolase family 3 signature 75 94 1.1E-37 T 31-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 PRINTS PR00133 Glycosyl hydrolase family 3 signature 152 168 1.1E-37 T 31-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 Pfam PF14310 Fibronectin type III-like domain 611 680 1.1E-21 T 31-10-2018 IPR026891 Fibronectin type III-like domain N186_00235 e43b34756a78be951f72c45bfa0b5e56 699 Gene3D G3DSA:3.40.50.1700 304 580 1.1E-95 T 31-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 N186_07875 5dab9565010c411a2eae53054475be97 176 Gene3D G3DSA:1.20.120.330 41 169 3.9E-37 T 31-10-2018 N186_07875 5dab9565010c411a2eae53054475be97 176 Pfam PF05942 Archaeal PaREP1/PaREP8 family 43 155 2.4E-30 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_03760 2c70e265e71d57d86ea43a4aff87e29c 284 SUPERFAMILY SSF53335 37 273 1.91E-29 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_03760 2c70e265e71d57d86ea43a4aff87e29c 284 Gene3D G3DSA:3.40.50.150 112 279 3.8E-20 T 31-10-2018 N186_03760 2c70e265e71d57d86ea43a4aff87e29c 284 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 178 247 2.6E-7 T 31-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 N186_00500 56e3c1dac14d641a5a0541bfab71877f 197 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 15 191 19.108 T 31-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 N186_00500 56e3c1dac14d641a5a0541bfab71877f 197 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 17 186 3.0E-32 T 31-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 N186_00500 56e3c1dac14d641a5a0541bfab71877f 197 Gene3D G3DSA:3.10.300.10 8 195 2.4E-28 T 31-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 N186_00500 56e3c1dac14d641a5a0541bfab71877f 197 SUPERFAMILY SSF50486 10 186 6.75E-31 T 31-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 N186_04455 62af50ca12b3b8bcabbb5a44b31bc067 223 SUPERFAMILY SSF53271 8 175 4.06E-33 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_04455 62af50ca12b3b8bcabbb5a44b31bc067 223 Gene3D G3DSA:3.40.50.2020 3 178 1.8E-37 T 31-10-2018 N186_04455 62af50ca12b3b8bcabbb5a44b31bc067 223 Pfam PF00156 Phosphoribosyl transferase domain 18 144 1.7E-14 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 N186_08570 9833f5f47cd1eea333b2ee301325a122 335 Gene3D G3DSA:3.40.50.300 3 252 3.1E-61 T 31-10-2018 N186_08570 9833f5f47cd1eea333b2ee301325a122 335 Pfam PF00005 ABC transporter 35 178 4.3E-26 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_08570 9833f5f47cd1eea333b2ee301325a122 335 SUPERFAMILY SSF52540 9 240 6.89E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08570 9833f5f47cd1eea333b2ee301325a122 335 SMART SM00382 43 235 4.1E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_08570 9833f5f47cd1eea333b2ee301325a122 335 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 30 328 5.1E-94 T 31-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 N186_08570 9833f5f47cd1eea333b2ee301325a122 335 Pfam PF13732 Domain of unknown function (DUF4162) 232 326 1.4E-9 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 N186_06845 524161d902132e6fc830090881b361ab 525 SUPERFAMILY SSF53067 272 513 8.55E-82 T 31-10-2018 N186_06845 524161d902132e6fc830090881b361ab 525 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 379 399 - T 31-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 N186_06845 524161d902132e6fc830090881b361ab 525 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 31-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 N186_06845 524161d902132e6fc830090881b361ab 525 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 278 467 2.9E-54 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 N186_06845 524161d902132e6fc830090881b361ab 525 Gene3D G3DSA:3.30.420.40 1 269 5.4E-96 T 31-10-2018 N186_06845 524161d902132e6fc830090881b361ab 525 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 513 5.4E-204 T 31-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 N186_06845 524161d902132e6fc830090881b361ab 525 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 268 2.3E-71 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 N186_06845 524161d902132e6fc830090881b361ab 525 SUPERFAMILY SSF53067 3 269 3.89E-81 T 31-10-2018 N186_06845 524161d902132e6fc830090881b361ab 525 Gene3D G3DSA:3.30.420.40 271 517 2.5E-89 T 31-10-2018 N186_06845 524161d902132e6fc830090881b361ab 525 Hamap MF_00186 Glycerol kinase [glpK]. 2 514 54.417 T 31-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 N186_06845 524161d902132e6fc830090881b361ab 525 PIRSF PIRSF000538 2 518 4.6E-167 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 N186_05885 0f96e7f371d51ac673b54cef84a62613 196 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 92 98 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 N186_05885 0f96e7f371d51ac673b54cef84a62613 196 SUPERFAMILY SSF53335 6 157 6.42E-23 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_05885 0f96e7f371d51ac673b54cef84a62613 196 Gene3D G3DSA:3.40.50.150 7 165 3.6E-24 T 31-10-2018 N186_05885 0f96e7f371d51ac673b54cef84a62613 196 Pfam PF05175 Methyltransferase small domain 9 162 6.1E-14 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 306 322 6.9E-20 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 350 371 6.9E-20 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 215 223 6.9E-20 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 134 6.9E-20 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 254 278 6.9E-20 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 390 408 6.9E-20 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 380 402 6.9E-25 T 31-10-2018 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 132 6.9E-25 T 31-10-2018 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 214 232 6.9E-25 T 31-10-2018 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 276 6.9E-25 T 31-10-2018 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 348 364 6.9E-25 T 31-10-2018 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 112 411 6.2E-35 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 SUPERFAMILY SSF54292 18 91 2.02E-15 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 57 65 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 Gene3D G3DSA:3.10.20.440 6 94 2.0E-18 T 31-10-2018 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 91 5.4E-21 T 31-10-2018 N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 Gene3D G3DSA:3.50.50.60 226 356 1.0E-53 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 SUPERFAMILY SSF51905 102 419 1.06E-47 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_06260 65bda62a86197af2f33d9ffdff6deda1 466 Gene3D G3DSA:3.50.50.60 112 414 1.0E-53 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_02150 c9ef7e6e32fb750daf744f1baac0edef 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 14 139 2.5E-11 T 31-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 N186_02150 c9ef7e6e32fb750daf744f1baac0edef 365 Pfam PF00557 Metallopeptidase family M24 149 349 8.1E-68 T 31-10-2018 IPR000994 Peptidase M24 N186_02150 c9ef7e6e32fb750daf744f1baac0edef 365 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 296 308 - T 31-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site N186_02150 c9ef7e6e32fb750daf744f1baac0edef 365 Gene3D G3DSA:3.90.230.10 143 365 8.2E-79 T 31-10-2018 N186_02150 c9ef7e6e32fb750daf744f1baac0edef 365 SUPERFAMILY SSF53092 12 120 1.38E-9 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal N186_02150 c9ef7e6e32fb750daf744f1baac0edef 365 SUPERFAMILY SSF55920 143 363 6.8E-73 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like N186_02150 c9ef7e6e32fb750daf744f1baac0edef 365 Gene3D G3DSA:3.40.350.10 5 142 3.4E-11 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal N186_04675 ac0a84c9dbc30928b74ace30fd4d2dee 136 SUPERFAMILY SSF88723 7 132 5.05E-19 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_04675 ac0a84c9dbc30928b74ace30fd4d2dee 136 SMART SM00670 7 116 4.8E-7 T 31-10-2018 IPR002716 PIN domain N186_04675 ac0a84c9dbc30928b74ace30fd4d2dee 136 Gene3D G3DSA:3.40.50.1010 6 135 5.3E-25 T 31-10-2018 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 49 103 1.3E-16 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 SMART SM00926 49 103 1.4E-18 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Gene3D G3DSA:3.40.50.740 108 188 8.3E-6 T 31-10-2018 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 SUPERFAMILY SSF53706 46 578 2.62E-138 T 31-10-2018 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 10 30 4.9E-4 T 31-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Pfam PF00384 Molybdopterin oxidoreductase 106 584 3.7E-42 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Gene3D G3DSA:3.40.228.10 359 680 1.4E-50 T 31-10-2018 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Gene3D G3DSA:2.40.40.20 704 841 1.0E-29 T 31-10-2018 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Gene3D G3DSA:2.20.25.90 43 107 7.8E-24 T 31-10-2018 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Gene3D G3DSA:3.40.228.10 189 324 9.6E-29 T 31-10-2018 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 SUPERFAMILY SSF50692 667 841 1.64E-19 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Gene3D G3DSA:3.40.50.740 469 599 1.4E-50 T 31-10-2018 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Gene3D G3DSA:3.30.2070.10 541 653 1.4E-50 T 31-10-2018 N186_08445 9a1c00b49df966a4855cd4a2ed8aa8bf 841 Pfam PF01568 Molydopterin dinucleotide binding domain 716 834 3.0E-11 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 N186_04445 6933759a4a22adf9ccc2e8abd98fa828 262 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 4 262 45.986 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 N186_04445 6933759a4a22adf9ccc2e8abd98fa828 262 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 6 242 7.0E-104 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 N186_04445 6933759a4a22adf9ccc2e8abd98fa828 262 SUPERFAMILY SSF53167 4 261 8.77E-100 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 N186_04445 6933759a4a22adf9ccc2e8abd98fa828 262 Pfam PF01048 Phosphorylase superfamily 5 242 1.3E-53 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 N186_04445 6933759a4a22adf9ccc2e8abd98fa828 262 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 52 92 - T 31-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 N186_04445 6933759a4a22adf9ccc2e8abd98fa828 262 Gene3D G3DSA:3.40.50.1580 1 262 1.2E-108 T 31-10-2018 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 Pfam PF00009 Elongation factor Tu GTP binding domain 26 232 3.6E-30 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 PRINTS PR00315 GTP-binding elongation factor signature 92 102 1.3E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 PRINTS PR00315 GTP-binding elongation factor signature 26 39 1.3E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 PRINTS PR00315 GTP-binding elongation factor signature 144 153 1.3E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 PRINTS PR00315 GTP-binding elongation factor signature 108 119 1.3E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 Gene3D G3DSA:2.40.30.10 250 366 2.6E-36 T 31-10-2018 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 Pfam PF03144 Elongation factor Tu domain 2 264 343 2.0E-12 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 20 612 41.121 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 Gene3D G3DSA:2.40.30.10 483 572 1.0E-29 T 31-10-2018 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 Gene3D G3DSA:3.40.50.10050 367 473 1.8E-32 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 SUPERFAMILY SSF50447 483 601 2.91E-23 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 SUPERFAMILY SSF52540 23 307 1.77E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 Gene3D G3DSA:3.40.50.300 16 246 2.5E-61 T 31-10-2018 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 26 154 1.0E-19 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 22 609 2.8E-228 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 Pfam PF14578 Elongation factor Tu domain 4 484 569 3.7E-32 T 31-10-2018 IPR029459 Elongation factor Tu-type domain N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 Pfam PF11987 Translation-initiation factor 2 359 462 4.4E-18 T 31-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 N186_03815 334f99ca1e4963a05d858ff9ad1e1dbd 613 SUPERFAMILY SSF52156 351 475 8.11E-32 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily N186_01585 a26beb665981436e31db5a7629078564 576 Gene3D G3DSA:2.60.40.1120 33 108 2.2E-10 T 31-10-2018 N186_01585 a26beb665981436e31db5a7629078564 576 Pfam PF13620 Carboxypeptidase regulatory-like domain 35 101 1.3E-11 T 31-10-2018 N186_01585 a26beb665981436e31db5a7629078564 576 SUPERFAMILY SSF49464 34 100 5.49E-12 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily N186_05980 e72a13f6c07a6544d28723a473d1a1f9 613 Pfam PF01865 Protein of unknown function DUF47 401 599 4.8E-19 T 31-10-2018 IPR018445 Putative phosphate transport regulator N186_05980 e72a13f6c07a6544d28723a473d1a1f9 613 Gene3D G3DSA:1.20.58.220 397 599 2.6E-27 T 31-10-2018 IPR038078 PhoU-like domain superfamily N186_05980 e72a13f6c07a6544d28723a473d1a1f9 613 Gene3D G3DSA:1.20.1250.20 3 208 7.9E-13 T 31-10-2018 N186_05980 e72a13f6c07a6544d28723a473d1a1f9 613 Pfam PF07690 Major Facilitator Superfamily 10 258 2.0E-16 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_05980 e72a13f6c07a6544d28723a473d1a1f9 613 SUPERFAMILY SSF103473 5 392 2.49E-44 T 31-10-2018 IPR036259 MFS transporter superfamily N186_05980 e72a13f6c07a6544d28723a473d1a1f9 613 Gene3D G3DSA:1.20.1250.20 209 396 3.0E-22 T 31-10-2018 N186_00220 7d1fc99c8d4832af49b725a4a8d57184 372 SMART SM00981 70 159 6.6E-21 T 31-10-2018 IPR004114 THUMP domain GO:0003723 N186_00220 7d1fc99c8d4832af49b725a4a8d57184 372 SUPERFAMILY SSF143437 14 157 1.66E-24 T 31-10-2018 N186_00220 7d1fc99c8d4832af49b725a4a8d57184 372 Gene3D G3DSA:3.30.2130.30 7 159 1.6E-24 T 31-10-2018 N186_00220 7d1fc99c8d4832af49b725a4a8d57184 372 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 180 355 1.5E-66 T 31-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP N186_00220 7d1fc99c8d4832af49b725a4a8d57184 372 SUPERFAMILY SSF75217 200 335 5.49E-7 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases N186_00220 7d1fc99c8d4832af49b725a4a8d57184 372 Pfam PF02926 THUMP domain 44 159 1.8E-24 T 31-10-2018 IPR004114 THUMP domain GO:0003723 N186_03880 5fa759b97bf6e86f5e58c1911102a802 270 SMART SM00650 29 194 3.1E-40 T 31-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 N186_03880 5fa759b97bf6e86f5e58c1911102a802 270 SUPERFAMILY SSF53335 15 262 2.81E-45 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_03880 5fa759b97bf6e86f5e58c1911102a802 270 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 42 69 - T 31-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 N186_03880 5fa759b97bf6e86f5e58c1911102a802 270 Pfam PF00398 Ribosomal RNA adenine dimethylase 16 257 2.7E-27 T 31-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm N186_03880 5fa759b97bf6e86f5e58c1911102a802 270 Gene3D G3DSA:3.40.50.150 10 196 1.4E-39 T 31-10-2018 N186_03880 5fa759b97bf6e86f5e58c1911102a802 270 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 262 1.6E-61 T 31-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 N186_05320 c3973a1b8b63395f5d5eb3833fcde491 459 Gene3D G3DSA:2.130.10.10 24 375 1.7E-8 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 N186_05320 c3973a1b8b63395f5d5eb3833fcde491 459 Pfam PF13620 Carboxypeptidase regulatory-like domain 391 443 4.3E-8 T 31-10-2018 N186_05320 c3973a1b8b63395f5d5eb3833fcde491 459 SUPERFAMILY SSF82171 34 375 1.53E-14 T 31-10-2018 N186_05320 c3973a1b8b63395f5d5eb3833fcde491 459 Gene3D G3DSA:2.60.40.1120 391 450 4.1E-7 T 31-10-2018 N186_05320 c3973a1b8b63395f5d5eb3833fcde491 459 SUPERFAMILY SSF49464 392 443 2.0E-9 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily N186_06910 dbd9033e3ed67d2a9e8a7be105103e87 182 SMART SM00903 16 155 8.4E-29 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 N186_06910 dbd9033e3ed67d2a9e8a7be105103e87 182 Gene3D G3DSA:2.30.110.10 4 181 5.2E-51 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 N186_06910 dbd9033e3ed67d2a9e8a7be105103e87 182 SUPERFAMILY SSF50475 12 177 1.47E-46 T 31-10-2018 N186_06910 dbd9033e3ed67d2a9e8a7be105103e87 182 Pfam PF01613 Flavin reductase like domain 20 170 4.2E-28 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 N186_08095 10af93d29c7cf65ea386d16b77f9d506 70 Gene3D G3DSA:2.10.260.10 1 39 1.8E-15 T 31-10-2018 N186_08095 10af93d29c7cf65ea386d16b77f9d506 70 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 1 41 3.0E-15 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08095 10af93d29c7cf65ea386d16b77f9d506 70 SUPERFAMILY SSF89447 1 42 5.58E-13 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_08095 10af93d29c7cf65ea386d16b77f9d506 70 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 1 43 2.6E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08095 10af93d29c7cf65ea386d16b77f9d506 70 SMART SM00966 1 46 2.8E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_01635 fa8871422d897c6ebd26703fdbead9e1 253 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 231 1.8E-40 T 31-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 N186_01635 fa8871422d897c6ebd26703fdbead9e1 253 Gene3D G3DSA:3.40.1210.10 1 250 1.2E-48 T 31-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 N186_01635 fa8871422d897c6ebd26703fdbead9e1 253 SUPERFAMILY SSF64167 2 244 5.1E-47 T 31-10-2018 N186_01635 fa8871422d897c6ebd26703fdbead9e1 253 Pfam PF01975 Survival protein SurE 2 177 1.4E-38 T 31-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 N186_02395 ac3559cce3770a2ead194d43833788e1 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 90 98 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_02395 ac3559cce3770a2ead194d43833788e1 545 SUPERFAMILY SSF52029 213 379 3.92E-61 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily N186_02395 ac3559cce3770a2ead194d43833788e1 545 Gene3D G3DSA:3.50.7.10 219 370 1.1E-207 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily N186_02395 ac3559cce3770a2ead194d43833788e1 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 38 54 1.7E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_02395 ac3559cce3770a2ead194d43833788e1 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 60 78 1.7E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_02395 ac3559cce3770a2ead194d43833788e1 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 374 396 1.7E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_02395 ac3559cce3770a2ead194d43833788e1 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 90 109 1.7E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_02395 ac3559cce3770a2ead194d43833788e1 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 408 420 1.7E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 N186_02395 ac3559cce3770a2ead194d43833788e1 545 SUPERFAMILY SSF48592 18 526 1.15E-87 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily N186_02395 ac3559cce3770a2ead194d43833788e1 545 SUPERFAMILY SSF54849 148 405 7.32E-31 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily N186_02395 ac3559cce3770a2ead194d43833788e1 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 9 526 6.8E-236 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 N186_02395 ac3559cce3770a2ead194d43833788e1 545 Gene3D G3DSA:1.10.560.10 29 523 1.1E-207 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily N186_02395 ac3559cce3770a2ead194d43833788e1 545 Gene3D G3DSA:3.30.260.10 148 406 1.1E-207 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily N186_02395 ac3559cce3770a2ead194d43833788e1 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 36 526 5.5E-185 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 N186_05390 e5c96ab926c3c005384443ccadd5af98 253 Gene3D G3DSA:3.40.50.10900 2 246 2.3E-56 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily N186_05390 e5c96ab926c3c005384443ccadd5af98 253 Pfam PF09754 PAC2 family 20 229 3.0E-39 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 N186_05390 e5c96ab926c3c005384443ccadd5af98 253 SUPERFAMILY SSF159659 7 238 8.24E-38 T 31-10-2018 N186_06490 a0ff95a254f6abfdb4153aecca32e65c 240 Gene3D G3DSA:2.40.30.130 1 89 8.7E-18 T 31-10-2018 N186_06490 a0ff95a254f6abfdb4153aecca32e65c 240 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 192 235 1.3E-9 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 N186_06490 a0ff95a254f6abfdb4153aecca32e65c 240 SUPERFAMILY SSF50447 3 87 1.91E-9 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_06490 a0ff95a254f6abfdb4153aecca32e65c 240 Pfam PF01411 tRNA synthetases class II (A) 13 93 5.0E-7 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 N186_06490 a0ff95a254f6abfdb4153aecca32e65c 240 Gene3D G3DSA:3.30.980.10 90 240 8.0E-31 T 31-10-2018 N186_06490 a0ff95a254f6abfdb4153aecca32e65c 240 SUPERFAMILY SSF55186 93 237 2.22E-32 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 N186_06490 a0ff95a254f6abfdb4153aecca32e65c 240 SMART SM00863 192 235 7.6E-12 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 N186_03770 dcf10ea357ca2f310be73706738d4c84 294 TIGRFAM TIGR01230 agmatinase: agmatinase 19 286 4.4E-66 T 31-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 N186_03770 dcf10ea357ca2f310be73706738d4c84 294 Pfam PF00491 Arginase family 26 286 4.4E-64 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 N186_03770 dcf10ea357ca2f310be73706738d4c84 294 PIRSF PIRSF036979 1 291 2.8E-75 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 N186_03770 dcf10ea357ca2f310be73706738d4c84 294 Gene3D G3DSA:3.40.800.10 19 290 6.1E-74 T 31-10-2018 N186_03770 dcf10ea357ca2f310be73706738d4c84 294 SUPERFAMILY SSF52768 7 288 1.46E-69 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily N186_03770 dcf10ea357ca2f310be73706738d4c84 294 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 31-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 N186_07365 ce39ab426d89e52be5175389d0cc6827 118 SUPERFAMILY SSF88723 1 115 2.8E-24 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_07365 ce39ab426d89e52be5175389d0cc6827 118 Gene3D G3DSA:3.40.50.1010 1 118 9.6E-26 T 31-10-2018 N186_07365 ce39ab426d89e52be5175389d0cc6827 118 SMART SM00670 1 106 0.0032 T 31-10-2018 IPR002716 PIN domain N186_07365 ce39ab426d89e52be5175389d0cc6827 118 Pfam PF01850 PIN domain 17 109 1.9E-9 T 31-10-2018 IPR002716 PIN domain N186_03500 b2eb241b1e6b9361c79556a1cc0e592f 145 Gene3D G3DSA:3.30.360.110 12 71 1.9E-20 T 31-10-2018 N186_03500 b2eb241b1e6b9361c79556a1cc0e592f 145 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 13 122 1.0E-44 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 N186_03500 b2eb241b1e6b9361c79556a1cc0e592f 145 Gene3D G3DSA:3.30.160.750 72 130 3.8E-25 T 31-10-2018 N186_03500 b2eb241b1e6b9361c79556a1cc0e592f 145 Pfam PF02675 S-adenosylmethionine decarboxylase 16 122 3.7E-37 T 31-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 N186_03500 b2eb241b1e6b9361c79556a1cc0e592f 145 SUPERFAMILY SSF56276 13 123 1.86E-42 T 31-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 N186_03500 b2eb241b1e6b9361c79556a1cc0e592f 145 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 10 126 31.745 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 N186_02470 df8cb11dd2efb333a0cc86dc256b1047 56 SUPERFAMILY SSF143100 3 49 1.12E-10 T 31-10-2018 IPR035069 TTHA1013/TTHA0281-like N186_02470 df8cb11dd2efb333a0cc86dc256b1047 56 Gene3D G3DSA:3.30.160.250 1 55 4.7E-9 T 31-10-2018 N186_05275 b1c1d4ab97c113fc1947a4a0cfe146d5 300 Pfam PF01040 UbiA prenyltransferase family 22 258 1.5E-35 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 N186_05275 b1c1d4ab97c113fc1947a4a0cfe146d5 300 PIRSF PIRSF005355 1 296 4.5E-63 T 31-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 N186_04660 f7999861237f68a1d0caa1fd2eab8444 361 Pfam PF01170 Putative RNA methylase family UPF0020 182 333 4.4E-15 T 31-10-2018 IPR000241 Putative RNA methylase domain N186_04660 f7999861237f68a1d0caa1fd2eab8444 361 Gene3D G3DSA:3.40.50.150 179 360 5.5E-24 T 31-10-2018 N186_04660 f7999861237f68a1d0caa1fd2eab8444 361 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 286 292 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 N186_04660 f7999861237f68a1d0caa1fd2eab8444 361 SUPERFAMILY SSF53335 182 331 3.44E-21 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_05650 701d630264788212afeda0a3da5377dc 263 Gene3D G3DSA:3.40.50.300 2 159 8.1E-43 T 31-10-2018 N186_05650 701d630264788212afeda0a3da5377dc 263 Gene3D G3DSA:1.10.1580.10 161 247 4.0E-17 T 31-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily N186_05650 701d630264788212afeda0a3da5377dc 263 SUPERFAMILY SSF52540 4 165 5.02E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05650 701d630264788212afeda0a3da5377dc 263 PIRSF PIRSF006230 1 257 5.4E-52 T 31-10-2018 IPR016478 GTPase, MTG1 N186_05650 701d630264788212afeda0a3da5377dc 263 Pfam PF01926 50S ribosome-binding GTPase 105 165 4.7E-14 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_05650 701d630264788212afeda0a3da5377dc 263 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 105 125 5.5E-7 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_05650 701d630264788212afeda0a3da5377dc 263 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 151 166 5.5E-7 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_05770 73573a24a17ddb2814ce886b451e353a 206 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 20 52 5.6E-9 T 31-10-2018 IPR001451 Hexapeptide repeat N186_05770 73573a24a17ddb2814ce886b451e353a 206 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 140 8.7E-8 T 31-10-2018 IPR001451 Hexapeptide repeat N186_05770 73573a24a17ddb2814ce886b451e353a 206 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 55 89 7.1E-8 T 31-10-2018 IPR001451 Hexapeptide repeat N186_05770 73573a24a17ddb2814ce886b451e353a 206 Gene3D G3DSA:2.160.10.10 1 156 9.3E-47 T 31-10-2018 N186_05770 73573a24a17ddb2814ce886b451e353a 206 SUPERFAMILY SSF51161 5 161 2.12E-47 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily N186_05770 73573a24a17ddb2814ce886b451e353a 206 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 114 142 - T 31-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 N186_01195 2f46e1b105c6a7848d5fb9804e48381d 330 Gene3D G3DSA:3.40.50.150 5 145 1.3E-19 T 31-10-2018 N186_01195 2f46e1b105c6a7848d5fb9804e48381d 330 SUPERFAMILY SSF53335 151 315 3.69E-24 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_01195 2f46e1b105c6a7848d5fb9804e48381d 330 SUPERFAMILY SSF53335 35 139 2.46E-21 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_01195 2f46e1b105c6a7848d5fb9804e48381d 330 Pfam PF01555 DNA methylase 36 134 1.8E-13 T 31-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 N186_01195 2f46e1b105c6a7848d5fb9804e48381d 330 Pfam PF01555 DNA methylase 172 317 1.7E-10 T 31-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 N186_01195 2f46e1b105c6a7848d5fb9804e48381d 330 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 96 114 2.8E-7 T 31-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 N186_01195 2f46e1b105c6a7848d5fb9804e48381d 330 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 119 139 2.8E-7 T 31-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 N186_01195 2f46e1b105c6a7848d5fb9804e48381d 330 Gene3D G3DSA:3.40.50.150 155 329 8.9E-28 T 31-10-2018 N186_04335 236b84b35423619f931374256747d3b9 263 SUPERFAMILY SSF103501 6 245 3.01E-12 T 31-10-2018 IPR036197 NarG-like superfamily N186_06710 7f9aab640e9e414f3fe7e57431651d6b 222 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 3 212 3.3E-38 T 31-10-2018 N186_06710 7f9aab640e9e414f3fe7e57431651d6b 222 Gene3D G3DSA:3.40.50.1000 3 212 5.2E-43 T 31-10-2018 IPR023214 HAD superfamily N186_06710 7f9aab640e9e414f3fe7e57431651d6b 222 Gene3D G3DSA:3.90.1070.10 80 143 5.2E-43 T 31-10-2018 N186_06710 7f9aab640e9e414f3fe7e57431651d6b 222 SUPERFAMILY SSF56784 3 218 3.15E-36 T 31-10-2018 IPR036412 HAD-like superfamily N186_06710 7f9aab640e9e414f3fe7e57431651d6b 222 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 59 1.4E-7 T 31-10-2018 N186_06710 7f9aab640e9e414f3fe7e57431651d6b 222 Pfam PF08282 haloacid dehalogenase-like hydrolase 102 212 1.7E-18 T 31-10-2018 N186_06965 f924afd337903142b829d8816629c159 512 Gene3D G3DSA:3.30.420.40 4 244 3.4E-54 T 31-10-2018 N186_06965 f924afd337903142b829d8816629c159 512 PIRSF PIRSF000538 4 502 3.9E-104 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 N186_06965 f924afd337903142b829d8816629c159 512 Gene3D G3DSA:3.30.420.40 245 512 1.9E-63 T 31-10-2018 N186_06965 f924afd337903142b829d8816629c159 512 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 254 442 8.3E-29 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 N186_06965 f924afd337903142b829d8816629c159 512 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 243 3.8E-41 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 N186_06965 f924afd337903142b829d8816629c159 512 SUPERFAMILY SSF53067 7 244 4.45E-42 T 31-10-2018 N186_06965 f924afd337903142b829d8816629c159 512 SUPERFAMILY SSF53067 246 497 4.16E-46 T 31-10-2018 N186_03080 0ff11d3bd502292ef8576f96fe22c668 182 Pfam PF01467 Cytidylyltransferase-like 25 161 2.6E-11 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 N186_03080 0ff11d3bd502292ef8576f96fe22c668 182 Gene3D G3DSA:3.40.50.620 25 169 6.7E-38 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_03080 0ff11d3bd502292ef8576f96fe22c668 182 SUPERFAMILY SSF52374 22 166 2.25E-20 T 31-10-2018 N186_03080 0ff11d3bd502292ef8576f96fe22c668 182 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 23 78 6.1E-13 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 N186_03520 1c76b0b9f56cfa2dc4081a750accf25a 193 Pfam PF00013 KH domain 12 70 1.1E-6 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 N186_03520 1c76b0b9f56cfa2dc4081a750accf25a 193 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 13 184 2.3E-52 T 31-10-2018 IPR019964 KH domain protein, archaea N186_03520 1c76b0b9f56cfa2dc4081a750accf25a 193 Gene3D G3DSA:3.30.1370.10 6 87 4.6E-14 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 N186_03520 1c76b0b9f56cfa2dc4081a750accf25a 193 Gene3D G3DSA:3.30.1370.10 88 191 3.1E-28 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 N186_03520 1c76b0b9f56cfa2dc4081a750accf25a 193 SMART SM00322 4 75 1.0E-5 T 31-10-2018 IPR004087 K Homology domain GO:0003676 N186_03520 1c76b0b9f56cfa2dc4081a750accf25a 193 SMART SM00322 102 161 0.048 T 31-10-2018 IPR004087 K Homology domain GO:0003676 N186_03520 1c76b0b9f56cfa2dc4081a750accf25a 193 SUPERFAMILY SSF54791 14 84 5.78E-8 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 N186_03520 1c76b0b9f56cfa2dc4081a750accf25a 193 SUPERFAMILY SSF54791 94 174 4.25E-13 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 N186_05665 c91ba365d269f2aab89683d1ca56253e 277 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 15 131 6.4E-14 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05665 c91ba365d269f2aab89683d1ca56253e 277 Gene3D G3DSA:3.40.120.10 153 271 1.2E-12 T 31-10-2018 N186_05665 c91ba365d269f2aab89683d1ca56253e 277 SUPERFAMILY SSF53738 155 259 1.18E-5 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05665 c91ba365d269f2aab89683d1ca56253e 277 Gene3D G3DSA:3.40.120.10 10 144 1.9E-20 T 31-10-2018 N186_05665 c91ba365d269f2aab89683d1ca56253e 277 SUPERFAMILY SSF53738 13 137 4.32E-15 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05665 c91ba365d269f2aab89683d1ca56253e 277 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 5.4E-7 T 31-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_07725 28d00e8c127452504351517f5942a859 297 SUPERFAMILY SSF109755 122 241 3.27E-10 T 31-10-2018 N186_07725 28d00e8c127452504351517f5942a859 297 Pfam PF01895 PhoU domain 135 216 7.6E-9 T 31-10-2018 IPR026022 PhoU domain N186_07725 28d00e8c127452504351517f5942a859 297 Gene3D G3DSA:1.20.58.220 124 227 7.0E-8 T 31-10-2018 IPR038078 PhoU-like domain superfamily N186_08325 db9fecc1eb2edbb6a020476ec6a82b25 499 Gene3D G3DSA:3.40.190.10 112 447 2.0E-81 T 31-10-2018 N186_08325 db9fecc1eb2edbb6a020476ec6a82b25 499 Pfam PF01547 Bacterial extracellular solute-binding protein 124 371 1.9E-18 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein N186_08325 db9fecc1eb2edbb6a020476ec6a82b25 499 Gene3D G3DSA:3.40.190.10 226 461 2.0E-81 T 31-10-2018 N186_08325 db9fecc1eb2edbb6a020476ec6a82b25 499 SUPERFAMILY SSF53850 108 484 3.26E-54 T 31-10-2018 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 Gene3D G3DSA:3.30.470.30 195 392 1.5E-57 T 31-10-2018 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 Hamap MF_00407 DNA ligase [lig]. 2 520 27.846 T 31-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 81 516 1.4E-107 T 31-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 Gene3D G3DSA:1.10.3260.10 1 192 1.1E-46 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 SUPERFAMILY SSF50249 395 517 4.97E-36 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 SUPERFAMILY SSF56091 192 393 4.32E-45 T 31-10-2018 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 Pfam PF04675 DNA ligase N terminus 4 149 1.9E-20 T 31-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 Pfam PF01068 ATP dependent DNA ligase domain 198 393 1.4E-50 T 31-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 SUPERFAMILY SSF117018 3 206 9.81E-38 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 Gene3D G3DSA:2.40.50.140 393 528 1.4E-41 T 31-10-2018 N186_03145 7dde6bb0870b7f2afd5facf42508bc32 533 Pfam PF04679 ATP dependent DNA ligase C terminal region 412 504 4.7E-18 T 31-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 N186_03225 994e3bec5cc97a09368b984b2d559f1c 314 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 55 220 4.2E-26 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 N186_03225 994e3bec5cc97a09368b984b2d559f1c 314 SUPERFAMILY SSF52518 18 313 1.93E-84 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold N186_03225 994e3bec5cc97a09368b984b2d559f1c 314 Gene3D G3DSA:3.40.50.970 98 314 6.8E-72 T 31-10-2018 N186_03225 994e3bec5cc97a09368b984b2d559f1c 314 Gene3D G3DSA:3.40.50.970 7 97 5.1E-10 T 31-10-2018 N186_02560 eb7bbae826b8fec41457e2ab98cfbe9b 196 Gene3D G3DSA:3.40.1170.20 16 83 3.7E-19 T 31-10-2018 N186_02560 eb7bbae826b8fec41457e2ab98cfbe9b 196 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 16 79 2.7E-17 T 31-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 N186_02560 eb7bbae826b8fec41457e2ab98cfbe9b 196 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 90 172 6.7E-12 T 31-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 N186_02560 eb7bbae826b8fec41457e2ab98cfbe9b 196 SUPERFAMILY SSF53032 89 176 3.84E-14 T 31-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 N186_02560 eb7bbae826b8fec41457e2ab98cfbe9b 196 Gene3D G3DSA:3.40.1350.10 90 178 2.1E-13 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 N186_02560 eb7bbae826b8fec41457e2ab98cfbe9b 196 SUPERFAMILY SSF55267 16 85 4.9E-15 T 31-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 N186_09645 7a2ea086ed9e1a8a2b5ec9c5969a2ad5 338 SUPERFAMILY SSF53901 8 337 5.47E-47 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_09645 7a2ea086ed9e1a8a2b5ec9c5969a2ad5 338 Gene3D G3DSA:3.40.47.10 7 338 3.0E-85 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_09645 7a2ea086ed9e1a8a2b5ec9c5969a2ad5 338 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 249 337 2.1E-23 T 31-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 N186_09645 7a2ea086ed9e1a8a2b5ec9c5969a2ad5 338 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 120 194 6.9E-15 T 31-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 N186_08270 f753359450fdf9a06e6f07063abda2e4 388 Pfam PF07690 Major Facilitator Superfamily 15 348 4.2E-26 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_08270 f753359450fdf9a06e6f07063abda2e4 388 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 N186_08270 f753359450fdf9a06e6f07063abda2e4 388 Gene3D G3DSA:1.20.1250.20 206 387 4.6E-13 T 31-10-2018 N186_08270 f753359450fdf9a06e6f07063abda2e4 388 Gene3D G3DSA:1.20.1250.20 11 199 4.3E-24 T 31-10-2018 N186_08270 f753359450fdf9a06e6f07063abda2e4 388 SUPERFAMILY SSF103473 10 385 1.7E-47 T 31-10-2018 IPR036259 MFS transporter superfamily N186_05360 dbbeb95da615d1ae77308ee6d6f3d44a 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 376 392 9.0E-15 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase N186_05360 dbbeb95da615d1ae77308ee6d6f3d44a 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 9.0E-15 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase N186_05360 dbbeb95da615d1ae77308ee6d6f3d44a 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 429 446 9.0E-15 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase N186_05360 dbbeb95da615d1ae77308ee6d6f3d44a 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 257 267 9.0E-15 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase N186_05360 dbbeb95da615d1ae77308ee6d6f3d44a 447 Pfam PF01189 16S rRNA methyltransferase RsmB/F 251 444 3.1E-33 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 N186_05360 dbbeb95da615d1ae77308ee6d6f3d44a 447 SUPERFAMILY SSF53335 146 446 7.15E-32 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_05360 dbbeb95da615d1ae77308ee6d6f3d44a 447 Gene3D G3DSA:3.40.50.150 167 446 8.9E-45 T 31-10-2018 N186_06240 4ca5d2103cd980840a713f3eb48a4e16 318 Pfam PF02272 DHHA1 domain 170 290 4.3E-8 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 N186_06240 4ca5d2103cd980840a713f3eb48a4e16 318 SUPERFAMILY SSF64182 21 293 2.62E-16 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily N186_06240 4ca5d2103cd980840a713f3eb48a4e16 318 Gene3D G3DSA:3.10.310.30 228 292 1.9E-6 T 31-10-2018 N186_01280 54d3248ee03f7f52849843fe832dba2c 551 Pfam PF02310 B12 binding domain 38 147 2.1E-11 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 N186_01280 54d3248ee03f7f52849843fe832dba2c 551 Pfam PF04055 Radical SAM superfamily 229 391 5.7E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_01280 54d3248ee03f7f52849843fe832dba2c 551 Gene3D G3DSA:3.80.30.20 222 411 1.6E-9 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe N186_01280 54d3248ee03f7f52849843fe832dba2c 551 SMART SM00729 224 470 5.4E-8 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_01280 54d3248ee03f7f52849843fe832dba2c 551 TIGRFAM TIGR04190 B12_SAM_Ta0216: B12-binding domain/radical SAM domain protein, Ta0216 family 5 531 3.6E-217 T 31-10-2018 IPR026447 B12-binding domain/radical SAM domain protein, Ta0216 family N186_01280 54d3248ee03f7f52849843fe832dba2c 551 SUPERFAMILY SSF102114 214 413 4.32E-22 T 31-10-2018 N186_05425 d0376723885df14129484511ce60b0db 623 SUPERFAMILY SSF52518 363 552 2.03E-33 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold N186_05425 d0376723885df14129484511ce60b0db 623 Gene3D G3DSA:3.40.50.970 375 561 1.6E-23 T 31-10-2018 N186_05425 d0376723885df14129484511ce60b0db 623 Gene3D G3DSA:3.40.50.970 2 192 4.1E-60 T 31-10-2018 N186_05425 d0376723885df14129484511ce60b0db 623 Gene3D G3DSA:3.30.70.20 564 616 4.1E-11 T 31-10-2018 N186_05425 d0376723885df14129484511ce60b0db 623 SUPERFAMILY SSF52922 234 299 6.67E-8 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 N186_05425 d0376723885df14129484511ce60b0db 623 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 600 611 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_05425 d0376723885df14129484511ce60b0db 623 Pfam PF00037 4Fe-4S binding domain 593 616 3.9E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_05425 d0376723885df14129484511ce60b0db 623 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 25 189 3.2E-15 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 N186_05425 d0376723885df14129484511ce60b0db 623 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 541 6.3E-29 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 N186_05425 d0376723885df14129484511ce60b0db 623 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 13 615 4.2E-230 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 N186_05425 d0376723885df14129484511ce60b0db 623 PIRSF PIRSF006439 2 622 3.0E-221 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 N186_05425 d0376723885df14129484511ce60b0db 623 SUPERFAMILY SSF52518 11 224 6.93E-57 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold N186_05425 d0376723885df14129484511ce60b0db 623 SUPERFAMILY SSF54862 551 618 5.45E-14 T 31-10-2018 N186_07935 909c5dd550ba4543c00577249fb48cc1 356 Gene3D G3DSA:3.90.550.10 1 242 1.1E-70 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_07935 909c5dd550ba4543c00577249fb48cc1 356 SUPERFAMILY SSF53448 1 296 1.08E-74 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_07935 909c5dd550ba4543c00577249fb48cc1 356 Pfam PF00483 Nucleotidyl transferase 2 236 1.2E-49 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 N186_07935 909c5dd550ba4543c00577249fb48cc1 356 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 355 3.1E-140 T 31-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form N186_07935 909c5dd550ba4543c00577249fb48cc1 356 Gene3D G3DSA:2.160.10.10 243 355 5.4E-9 T 31-10-2018 N186_07935 909c5dd550ba4543c00577249fb48cc1 356 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 275 300 0.0018 T 31-10-2018 IPR001451 Hexapeptide repeat N186_09205 30c5d8924f5e00ce9a59e0e434d27524 1017 PIRSF PIRSF009427 1 990 1.5E-248 T 31-10-2018 IPR014455 DNA methylase, N-6 adenine-specific, MK1259 type N186_09205 30c5d8924f5e00ce9a59e0e434d27524 1017 Pfam PF06634 Protein of unknown function (DUF1156) 10 57 3.0E-9 T 31-10-2018 IPR009537 Domain of unknown function DUF1156 N186_09205 30c5d8924f5e00ce9a59e0e434d27524 1017 SUPERFAMILY SSF53335 571 750 1.73E-10 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_09205 30c5d8924f5e00ce9a59e0e434d27524 1017 SUPERFAMILY SSF53335 97 143 2.81E-7 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_09205 30c5d8924f5e00ce9a59e0e434d27524 1017 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 585 591 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 Gene3D G3DSA:3.30.70.20 351 417 2.7E-7 T 31-10-2018 N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 Pfam PF13237 4Fe-4S dicluster domain 319 369 4.0E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 Gene3D G3DSA:3.30.70.20 310 348 1.0E-5 T 31-10-2018 N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 Pfam PF00037 4Fe-4S binding domain 160 176 9.2E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 SUPERFAMILY SSF54862 296 379 1.95E-19 T 31-10-2018 N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 358 369 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 163 174 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 SUPERFAMILY SSF54862 125 184 8.79E-12 T 31-10-2018 N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 Gene3D G3DSA:3.30.70.20 126 198 1.4E-8 T 31-10-2018 N186_09725 619c5c4dd8484c843280f22c7e1e1403 458 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 326 337 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_08360 5363bb927a919f613e41cc2b2b0acf40 325 SUPERFAMILY SSF53300 104 272 1.23E-28 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily N186_08360 5363bb927a919f613e41cc2b2b0acf40 325 Gene3D G3DSA:3.40.50.410 102 277 4.9E-31 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily N186_08360 5363bb927a919f613e41cc2b2b0acf40 325 SMART SM00327 102 272 3.0E-15 T 31-10-2018 IPR002035 von Willebrand factor, type A N186_08360 5363bb927a919f613e41cc2b2b0acf40 325 Pfam PF13519 von Willebrand factor type A domain 105 207 2.3E-15 T 31-10-2018 IPR002035 von Willebrand factor, type A N186_03125 a4c5acfc7caee8683157dc37a8be061f 125 SMART SM01405 7 122 7.2E-52 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03125 a4c5acfc7caee8683157dc37a8be061f 125 Pfam PF01092 Ribosomal protein S6e 7 120 2.0E-35 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03125 a4c5acfc7caee8683157dc37a8be061f 125 ProSitePatterns PS00578 Ribosomal protein S6e signature. 55 66 - T 31-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03125 a4c5acfc7caee8683157dc37a8be061f 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 5 117 18.838 T 31-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 N186_04140 f9f5a8dc4a8acbffbc31b695cff602db 443 Gene3D G3DSA:3.40.640.10 69 337 2.7E-171 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 N186_04140 f9f5a8dc4a8acbffbc31b695cff602db 443 PIRSF PIRSF000521 2 140 4.4E-11 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 N186_04140 f9f5a8dc4a8acbffbc31b695cff602db 443 PIRSF PIRSF000521 134 439 2.1E-53 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 N186_04140 f9f5a8dc4a8acbffbc31b695cff602db 443 SUPERFAMILY SSF53383 25 438 9.02E-140 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase N186_04140 f9f5a8dc4a8acbffbc31b695cff602db 443 Gene3D G3DSA:3.90.1150.10 13 434 2.7E-171 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 N186_04140 f9f5a8dc4a8acbffbc31b695cff602db 443 Pfam PF00202 Aminotransferase class-III 34 434 8.9E-135 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 N186_04140 f9f5a8dc4a8acbffbc31b695cff602db 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 N186_01230 0f0370fb5027055c01e86e9bfc41373f 260 Pfam PF05050 Methyltransferase FkbM domain 79 239 1.1E-10 T 31-10-2018 IPR006342 Methyltransferase FkbM N186_01230 0f0370fb5027055c01e86e9bfc41373f 260 Gene3D G3DSA:3.40.50.150 66 255 5.2E-23 T 31-10-2018 N186_01230 0f0370fb5027055c01e86e9bfc41373f 260 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 77 221 3.3E-22 T 31-10-2018 IPR006342 Methyltransferase FkbM N186_01230 0f0370fb5027055c01e86e9bfc41373f 260 SUPERFAMILY SSF53335 31 254 3.32E-36 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_08355 26f925c44b74d1917157c23ce465d7a3 320 SMART SM00327 98 275 1.2E-8 T 31-10-2018 IPR002035 von Willebrand factor, type A N186_08355 26f925c44b74d1917157c23ce465d7a3 320 Pfam PF00092 von Willebrand factor type A domain 101 251 3.2E-13 T 31-10-2018 IPR002035 von Willebrand factor, type A N186_08355 26f925c44b74d1917157c23ce465d7a3 320 Gene3D G3DSA:3.40.50.410 93 284 4.9E-20 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily N186_08355 26f925c44b74d1917157c23ce465d7a3 320 SUPERFAMILY SSF53300 100 251 3.97E-17 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily N186_06650 c56c2a75d29e023541647678c46cbe1d 171 Pfam PF01965 DJ-1/PfpI family 1 159 2.6E-43 T 31-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 N186_06650 c56c2a75d29e023541647678c46cbe1d 171 SUPERFAMILY SSF52317 1 164 2.29E-40 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like N186_06650 c56c2a75d29e023541647678c46cbe1d 171 Gene3D G3DSA:3.40.50.880 1 168 5.9E-45 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like N186_09680 1429be8bb5057c9e7456e8a0922c7d2d 511 SUPERFAMILY SSF56801 12 503 1.96E-137 T 31-10-2018 N186_09680 1429be8bb5057c9e7456e8a0922c7d2d 511 Pfam PF00501 AMP-binding enzyme 25 408 3.3E-92 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 N186_09680 1429be8bb5057c9e7456e8a0922c7d2d 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 492 1.3E-18 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain N186_09680 1429be8bb5057c9e7456e8a0922c7d2d 511 Gene3D G3DSA:3.30.300.310 405 504 8.9E-29 T 31-10-2018 N186_09680 1429be8bb5057c9e7456e8a0922c7d2d 511 Gene3D G3DSA:3.40.50.12780 8 404 2.3E-104 T 31-10-2018 N186_09680 1429be8bb5057c9e7456e8a0922c7d2d 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 165 176 - T 31-10-2018 IPR020845 AMP-binding, conserved site N186_01770 3e2c60d12123dd404fb70bfd5d2e6a68 481 Pfam PF01523 Putative modulator of DNA gyrase 23 332 2.5E-50 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 N186_01770 3e2c60d12123dd404fb70bfd5d2e6a68 481 PIRSF PIRSF004919 4 479 5.0E-142 T 31-10-2018 IPR025502 TldD N186_01770 3e2c60d12123dd404fb70bfd5d2e6a68 481 Gene3D G3DSA:3.30.2290.10 1 205 7.1E-17 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal N186_01770 3e2c60d12123dd404fb70bfd5d2e6a68 481 SUPERFAMILY SSF111283 2 476 3.92E-91 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 N186_06080 5b05027ad2ee80f911b106d671f59914 300 Gene3D G3DSA:3.40.50.1970 4 159 6.9E-7 T 31-10-2018 N186_06080 5b05027ad2ee80f911b106d671f59914 300 SUPERFAMILY SSF56796 46 134 1.01E-6 T 31-10-2018 N186_05265 11090869a280f93d110027a3ba04eb26 97 Pfam PF13190 PDGLE domain 50 92 3.6E-7 T 31-10-2018 IPR025937 PDGLE domain N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 Gene3D G3DSA:3.40.228.10 135 515 2.0E-122 T 31-10-2018 N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 Pfam PF01568 Molydopterin dinucleotide binding domain 542 637 9.3E-17 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 SUPERFAMILY SSF50692 535 643 4.07E-22 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 Gene3D G3DSA:3.40.50.740 74 460 2.0E-122 T 31-10-2018 N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 47 9.3E-6 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 SUPERFAMILY SSF53706 4 523 1.13E-131 T 31-10-2018 N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 Pfam PF00384 Molybdopterin oxidoreductase 58 456 5.6E-52 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 SMART SM00926 1 55 2.0E-7 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 Gene3D G3DSA:3.30.2070.10 415 497 2.0E-122 T 31-10-2018 N186_07610 859c2f24a5a8593971ed7efa24b8678d 648 Gene3D G3DSA:2.40.40.20 533 646 4.7E-20 T 31-10-2018 N186_01150 5490184781d1f8dd2f060162c837053f 157 SUPERFAMILY SSF110087 43 150 7.19E-5 T 31-10-2018 IPR036182 Copper chaperone PCuAC superfamily N186_01150 5490184781d1f8dd2f060162c837053f 157 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 4 27 1.4E-5 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal N186_07855 fac3d60e9bfbb44545c44b2b8b65c546 447 SUPERFAMILY SSF52540 2 233 6.9E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07855 fac3d60e9bfbb44545c44b2b8b65c546 447 SUPERFAMILY SSF46785 234 308 3.75E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_07855 fac3d60e9bfbb44545c44b2b8b65c546 447 Gene3D G3DSA:3.40.50.300 1 161 1.9E-21 T 31-10-2018 N186_07855 fac3d60e9bfbb44545c44b2b8b65c546 447 Pfam PF03008 Archaea bacterial proteins of unknown function 298 381 4.8E-19 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal N186_07855 fac3d60e9bfbb44545c44b2b8b65c546 447 Pfam PF01637 ATPase domain predominantly from Archaea 5 194 9.1E-13 T 31-10-2018 IPR011579 ATPase domain GO:0005524 N186_06060 608aec2deb07acf22249b829546400de 319 Pfam PF00480 ROK family 5 308 1.7E-63 T 31-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 N186_06060 608aec2deb07acf22249b829546400de 319 Gene3D G3DSA:3.30.420.40 5 308 4.2E-84 T 31-10-2018 N186_06060 608aec2deb07acf22249b829546400de 319 SUPERFAMILY SSF53067 1 310 7.21E-58 T 31-10-2018 N186_06060 608aec2deb07acf22249b829546400de 319 Gene3D G3DSA:3.30.420.40 125 295 4.2E-84 T 31-10-2018 N186_01805 bb51cb0d098d798ec1bb4427bf523b94 616 SUPERFAMILY SSF48310 224 615 3.79E-140 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_01805 bb51cb0d098d798ec1bb4427bf523b94 616 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 218 4.7E-77 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_01805 bb51cb0d098d798ec1bb4427bf523b94 616 Gene3D G3DSA:1.10.569.10 255 443 1.7E-142 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 N186_01805 bb51cb0d098d798ec1bb4427bf523b94 616 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 233 614 8.0E-148 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_01805 bb51cb0d098d798ec1bb4427bf523b94 616 SMART SM00790 5 220 1.3E-112 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 N186_01805 bb51cb0d098d798ec1bb4427bf523b94 616 Gene3D G3DSA:3.60.9.10 2 224 8.8E-80 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily N186_01805 bb51cb0d098d798ec1bb4427bf523b94 616 Gene3D G3DSA:1.10.599.10 253 614 1.7E-142 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 N186_01805 bb51cb0d098d798ec1bb4427bf523b94 616 SUPERFAMILY SSF56228 4 221 5.1E-68 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 Gene3D G3DSA:2.40.50.100 255 287 2.7E-6 T 31-10-2018 N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 SUPERFAMILY SSF52540 7 250 6.41E-90 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 SMART SM00382 31 218 2.3E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 Pfam PF08402 TOBE domain 285 350 1.7E-6 T 31-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 Pfam PF00005 ABC transporter 22 168 1.5E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 37 333 1.2E-109 T 31-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 Gene3D G3DSA:2.40.50.140 288 349 2.7E-6 T 31-10-2018 N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 Gene3D G3DSA:3.40.50.300 3 244 7.2E-79 T 31-10-2018 N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 SUPERFAMILY SSF50331 244 357 2.31E-13 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal N186_00605 3410d595e52bfbcd6b3fc19708cc9da5 360 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 Gene3D G3DSA:3.30.420.40 5 300 1.6E-95 T 31-10-2018 N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 2 328 37.043 T 31-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 Pfam PF00814 Glycoprotease family 25 295 1.3E-80 T 31-10-2018 IPR000905 Gcp-like domain N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 95 114 8.7E-34 T 31-10-2018 IPR017861 Kae1/TsaD family N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 127 139 8.7E-34 T 31-10-2018 IPR017861 Kae1/TsaD family N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 5 18 8.7E-34 T 31-10-2018 IPR017861 Kae1/TsaD family N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 74 94 8.7E-34 T 31-10-2018 IPR017861 Kae1/TsaD family N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 251 260 8.7E-34 T 31-10-2018 IPR017861 Kae1/TsaD family N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 149 170 8.7E-34 T 31-10-2018 IPR017861 Kae1/TsaD family N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 Gene3D G3DSA:3.30.420.40 125 281 1.6E-95 T 31-10-2018 N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 5 294 2.6E-85 T 31-10-2018 IPR017861 Kae1/TsaD family N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 327 2.9E-154 T 31-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 N186_03245 f986385d207f2c2136dc6a3be2e50dca 330 SUPERFAMILY SSF53067 3 293 2.04E-31 T 31-10-2018 N186_09100 02c0e814c4d70f6ebdfc0d966036f067 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 49 5.3E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_09100 02c0e814c4d70f6ebdfc0d966036f067 84 Gene3D G3DSA:2.10.260.10 4 47 1.3E-11 T 31-10-2018 N186_09100 02c0e814c4d70f6ebdfc0d966036f067 84 SMART SM00966 7 52 1.9E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_09100 02c0e814c4d70f6ebdfc0d966036f067 84 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 42 1.2E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_09100 02c0e814c4d70f6ebdfc0d966036f067 84 SUPERFAMILY SSF89447 5 45 3.66E-11 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_05730 34ad25a8da31f051cf70b7b56ca56022 259 Pfam PF01791 DeoC/LacD family aldolase 18 228 1.6E-33 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_05730 34ad25a8da31f051cf70b7b56ca56022 259 PIRSF PIRSF038992 1 257 1.9E-81 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_05730 34ad25a8da31f051cf70b7b56ca56022 259 SUPERFAMILY SSF51569 3 243 2.05E-63 T 31-10-2018 N186_05730 34ad25a8da31f051cf70b7b56ca56022 259 SMART SM01133 17 228 1.1E-35 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_05730 34ad25a8da31f051cf70b7b56ca56022 259 Gene3D G3DSA:3.20.20.70 1 256 1.8E-77 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_06945 3f0d803122c1bc107a62f060adcd36e9 298 SUPERFAMILY SSF51569 8 292 1.15E-73 T 31-10-2018 N186_06945 3f0d803122c1bc107a62f060adcd36e9 298 SMART SM01130 5 292 2.3E-76 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_06945 3f0d803122c1bc107a62f060adcd36e9 298 Pfam PF00701 Dihydrodipicolinate synthetase family 6 290 3.9E-56 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_06945 3f0d803122c1bc107a62f060adcd36e9 298 Gene3D G3DSA:3.20.20.70 1 292 5.6E-81 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_06945 3f0d803122c1bc107a62f060adcd36e9 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 5.9E-11 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_06945 3f0d803122c1bc107a62f060adcd36e9 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 5.9E-11 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_06945 3f0d803122c1bc107a62f060adcd36e9 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 5.9E-11 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_06945 3f0d803122c1bc107a62f060adcd36e9 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 5.9E-11 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_06945 3f0d803122c1bc107a62f060adcd36e9 298 PIRSF PIRSF001365 1 297 3.8E-69 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_06585 e5f513b8e49e81addbf7e1ce3f971584 434 Pfam PF00361 Proton-conducting membrane transporter 99 372 1.2E-59 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06585 e5f513b8e49e81addbf7e1ce3f971584 434 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 198 222 1.8E-10 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06585 e5f513b8e49e81addbf7e1ce3f971584 434 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 135 159 1.8E-10 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06585 e5f513b8e49e81addbf7e1ce3f971584 434 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 333 359 1.8E-10 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06585 e5f513b8e49e81addbf7e1ce3f971584 434 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 281 300 1.8E-10 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_04905 10513d76b81b3c2f570fbe968f7542be 171 Gene3D G3DSA:1.10.10.10 1 86 9.2E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04905 10513d76b81b3c2f570fbe968f7542be 171 SUPERFAMILY SSF46785 3 85 2.11E-20 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_04905 10513d76b81b3c2f570fbe968f7542be 171 PIRSF PIRSF006373 1 168 2.4E-47 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 N186_04905 10513d76b81b3c2f570fbe968f7542be 171 SUPERFAMILY SSF57783 110 142 2.38E-5 T 31-10-2018 N186_04905 10513d76b81b3c2f570fbe968f7542be 171 SMART SM00531 17 155 2.4E-26 T 31-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 N186_04905 10513d76b81b3c2f570fbe968f7542be 171 Pfam PF02002 TFIIE alpha subunit 5 108 2.0E-30 T 31-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 N186_04905 10513d76b81b3c2f570fbe968f7542be 171 Hamap MF_01909 Transcription factor E [tfe]. 1 164 23.872 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 N186_04905 10513d76b81b3c2f570fbe968f7542be 171 Pfam PF08271 TFIIB zinc-binding 113 152 1.0E-8 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type N186_03370 6b3749289a9794431bd17ad59102ed65 202 Pfam PF01380 SIS domain 39 141 7.5E-18 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 N186_03370 6b3749289a9794431bd17ad59102ed65 202 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 11 200 1.2E-66 T 31-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 N186_03370 6b3749289a9794431bd17ad59102ed65 202 Gene3D G3DSA:3.40.50.10490 4 200 2.1E-56 T 31-10-2018 N186_03370 6b3749289a9794431bd17ad59102ed65 202 SUPERFAMILY SSF53697 6 200 1.22E-37 T 31-10-2018 N186_05655 f6d50bc35549caf87b92e468091321ac 293 Pfam PF09171 N-glycosylase/DNA lyase 16 253 4.5E-54 T 31-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 N186_05655 f6d50bc35549caf87b92e468091321ac 293 SUPERFAMILY SSF48150 8 254 1.02E-51 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 N186_05655 f6d50bc35549caf87b92e468091321ac 293 Gene3D G3DSA:1.10.340.30 29 164 1.8E-30 T 31-10-2018 N186_05655 f6d50bc35549caf87b92e468091321ac 293 Gene3D G3DSA:1.10.1670.10 165 265 9.2E-15 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 N186_05070 753573c002645ec2667a7dd14f0f897a 240 SUPERFAMILY SSF56300 7 220 5.76E-28 T 31-10-2018 N186_05070 753573c002645ec2667a7dd14f0f897a 240 Gene3D G3DSA:3.60.21.10 5 237 1.0E-16 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_05070 753573c002645ec2667a7dd14f0f897a 240 Pfam PF00149 Calcineurin-like phosphoesterase 7 202 9.0E-14 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 N186_00670 4cc9fb9ccf8241f314dfe21d68a22e8f 320 SUPERFAMILY SSF51726 1 317 8.24E-25 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 N186_00670 4cc9fb9ccf8241f314dfe21d68a22e8f 320 Gene3D G3DSA:3.20.20.210 1 319 1.9E-27 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 N186_01520 7b5bbd88c1528dbde8cbc6adbfa3877c 304 Gene3D G3DSA:3.40.50.150 61 303 2.1E-79 T 31-10-2018 N186_01520 7b5bbd88c1528dbde8cbc6adbfa3877c 304 Gene3D G3DSA:2.30.140.10 8 59 1.6E-10 T 31-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 N186_01520 7b5bbd88c1528dbde8cbc6adbfa3877c 304 SUPERFAMILY SSF53335 9 287 3.75E-81 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_01520 7b5bbd88c1528dbde8cbc6adbfa3877c 304 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 86 99 - T 31-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 N186_01520 7b5bbd88c1528dbde8cbc6adbfa3877c 304 Pfam PF01564 Spermine/spermidine synthase domain 65 243 1.1E-49 T 31-10-2018 N186_01520 7b5bbd88c1528dbde8cbc6adbfa3877c 304 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 10 288 35.945 T 31-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 N186_01520 7b5bbd88c1528dbde8cbc6adbfa3877c 304 Pfam PF17284 Spermidine synthase tetramerisation domain 10 62 9.5E-8 T 31-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 Pfam PF00318 Ribosomal protein S2 126 190 3.0E-14 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 PRINTS PR00395 Ribosomal protein S2 signature 100 117 1.5E-22 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 PRINTS PR00395 Ribosomal protein S2 signature 142 153 1.5E-22 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 PRINTS PR00395 Ribosomal protein S2 signature 22 40 1.5E-22 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 PRINTS PR00395 Ribosomal protein S2 signature 52 61 1.5E-22 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 PRINTS PR00395 Ribosomal protein S2 signature 125 142 1.5E-22 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 PRINTS PR00395 Ribosomal protein S2 signature 163 177 1.5E-22 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 SUPERFAMILY SSF52313 19 203 7.19E-60 T 31-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 Gene3D G3DSA:3.40.50.10490 21 217 3.5E-66 T 31-10-2018 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 18 211 2.3E-86 T 31-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02275 a716c5dfdcbdcd6a2503c3ba471bee33 219 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 14 212 49.368 T 31-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_09005 c95ddc8e7b6d40883d9da8dd220d3aa6 91 Pfam PF14947 Winged helix-turn-helix 4 84 2.0E-18 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain N186_09005 c95ddc8e7b6d40883d9da8dd220d3aa6 91 SUPERFAMILY SSF46785 5 83 3.25E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_09005 c95ddc8e7b6d40883d9da8dd220d3aa6 91 Gene3D G3DSA:1.10.10.10 1 87 2.1E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_09005 c95ddc8e7b6d40883d9da8dd220d3aa6 91 SMART SM00418 6 79 0.0096 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_01990 3abee7c828d6a4c514c8393c372061f4 94 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 12 90 14.132 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 N186_01990 3abee7c828d6a4c514c8393c372061f4 94 Gene3D G3DSA:3.30.70.330 1 94 8.3E-34 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily N186_01990 3abee7c828d6a4c514c8393c372061f4 94 SUPERFAMILY SSF54189 13 86 2.3E-25 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_01990 3abee7c828d6a4c514c8393c372061f4 94 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 18 93 2.9E-36 T 31-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01990 3abee7c828d6a4c514c8393c372061f4 94 ProSitePatterns PS00050 Ribosomal protein L23 signature. 72 87 - T 31-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_01990 3abee7c828d6a4c514c8393c372061f4 94 Pfam PF00276 Ribosomal protein L23 14 80 4.7E-18 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 N186_01990 3abee7c828d6a4c514c8393c372061f4 94 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 14 94 25.818 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 N186_05030 71451ee8a1054f7c4163728214a60717 157 Hamap MF_00499 50S ribosomal protein L13e [rpl13e]. 7 85 18.202 T 31-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05030 71451ee8a1054f7c4163728214a60717 157 Pfam PF01294 Ribosomal protein L13e 29 79 8.5E-10 T 31-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05985 9336a1d513e6f97f8531c701b325c7e5 354 Pfam PF08608 Wyosine base formation 248 307 3.0E-17 T 31-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 N186_05985 9336a1d513e6f97f8531c701b325c7e5 354 Gene3D G3DSA:3.20.20.70 1 323 1.5E-107 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_05985 9336a1d513e6f97f8531c701b325c7e5 354 SUPERFAMILY SSF102114 60 264 9.22E-18 T 31-10-2018 N186_05985 9336a1d513e6f97f8531c701b325c7e5 354 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 12 307 8.6E-114 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 N186_05985 9336a1d513e6f97f8531c701b325c7e5 354 Pfam PF04055 Radical SAM superfamily 59 245 1.4E-13 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_05985 9336a1d513e6f97f8531c701b325c7e5 354 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 8 309 43.943 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 N186_04225 72fb59fc92691f381b8fd14bea4290a4 170 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 170 34.913 T 31-10-2018 IPR022981 Ribosomal protein L10e, archaea N186_04225 72fb59fc92691f381b8fd14bea4290a4 170 SUPERFAMILY SSF54686 4 165 6.8E-57 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 N186_04225 72fb59fc92691f381b8fd14bea4290a4 170 PIRSF PIRSF005590 1 170 1.2E-66 T 31-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04225 72fb59fc92691f381b8fd14bea4290a4 170 Gene3D G3DSA:3.90.1170.10 1 169 1.9E-64 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 N186_04225 72fb59fc92691f381b8fd14bea4290a4 170 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 31-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04225 72fb59fc92691f381b8fd14bea4290a4 170 Pfam PF00252 Ribosomal protein L16p/L10e 15 163 2.4E-30 T 31-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 N186_07840 c9161dc1632effe83eebee7d25d917a5 287 SMART SM00849 73 256 1.0E-6 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_07840 c9161dc1632effe83eebee7d25d917a5 287 SUPERFAMILY SSF56281 58 259 1.83E-30 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_07840 c9161dc1632effe83eebee7d25d917a5 287 Pfam PF00753 Metallo-beta-lactamase superfamily 76 132 2.9E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_07840 c9161dc1632effe83eebee7d25d917a5 287 Gene3D G3DSA:3.60.15.10 180 287 1.0E-26 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_07840 c9161dc1632effe83eebee7d25d917a5 287 Gene3D G3DSA:3.60.15.10 43 177 4.7E-31 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_01930 ecb1bd36c6901ebbbd43f9be4abd9f21 262 PIRSF PIRSF006779 1 262 1.4E-80 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase N186_01930 ecb1bd36c6901ebbbd43f9be4abd9f21 262 Gene3D G3DSA:3.40.50.10790 3 156 1.1E-55 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal N186_01930 ecb1bd36c6901ebbbd43f9be4abd9f21 262 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 6 257 2.2E-82 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase N186_01930 ecb1bd36c6901ebbbd43f9be4abd9f21 262 SUPERFAMILY SSF101852 162 260 3.27E-26 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal N186_01930 ecb1bd36c6901ebbbd43f9be4abd9f21 262 SUPERFAMILY SSF102522 4 152 4.32E-54 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal N186_01930 ecb1bd36c6901ebbbd43f9be4abd9f21 262 Gene3D G3DSA:2.40.30.90 160 260 3.8E-30 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 SUPERFAMILY SSF55424 321 443 3.44E-31 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 6.7E-22 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 385 400 6.7E-22 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.7E-22 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 6.7E-22 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 6.7E-22 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 7.7E-31 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 7.7E-31 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 7.7E-31 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 7.7E-31 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 7.7E-31 T 31-10-2018 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 305 4.8E-61 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 428 3.9E-19 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 SUPERFAMILY SSF51905 1 344 3.89E-47 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 Gene3D G3DSA:3.50.50.60 114 437 1.1E-144 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_01640 762682dd2552cd2e2c6040d5fe7851e8 447 Gene3D G3DSA:3.50.50.60 7 338 1.1E-144 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_05165 642fe3abb3094d5fcb31b0bdfa808dad 349 SMART SM01240 13 342 2.2E-149 T 31-10-2018 N186_05165 642fe3abb3094d5fcb31b0bdfa808dad 349 Gene3D G3DSA:3.20.20.70 5 348 6.4E-127 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_05165 642fe3abb3094d5fcb31b0bdfa808dad 349 SUPERFAMILY SSF51412 3 345 1.7E-106 T 31-10-2018 N186_05165 642fe3abb3094d5fcb31b0bdfa808dad 349 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 341 5.4E-114 T 31-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 N186_05335 0a70ae35ed0bca84b85ebadb2fc3e94d 242 SUPERFAMILY SSF51569 18 234 3.98E-65 T 31-10-2018 N186_05335 0a70ae35ed0bca84b85ebadb2fc3e94d 242 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 20 236 28.445 T 31-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 N186_05335 0a70ae35ed0bca84b85ebadb2fc3e94d 242 PIRSF PIRSF001357 16 239 1.3E-62 T 31-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_05335 0a70ae35ed0bca84b85ebadb2fc3e94d 242 Gene3D G3DSA:3.20.20.70 2 240 4.5E-74 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_05335 0a70ae35ed0bca84b85ebadb2fc3e94d 242 Pfam PF01791 DeoC/LacD family aldolase 30 206 1.1E-15 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_05335 0a70ae35ed0bca84b85ebadb2fc3e94d 242 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 22 232 7.8E-56 T 31-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_05335 0a70ae35ed0bca84b85ebadb2fc3e94d 242 SMART SM01133 21 234 1.3E-66 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_00475 826a06afeb5c78e0125217334f7460e6 453 Gene3D G3DSA:3.40.190.10 301 452 1.1E-10 T 31-10-2018 N186_00475 826a06afeb5c78e0125217334f7460e6 453 SUPERFAMILY SSF53850 79 447 2.08E-45 T 31-10-2018 N186_00475 826a06afeb5c78e0125217334f7460e6 453 Pfam PF13416 Bacterial extracellular solute-binding protein 100 412 5.1E-34 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein N186_00475 826a06afeb5c78e0125217334f7460e6 453 Gene3D G3DSA:3.40.190.10 54 215 3.7E-12 T 31-10-2018 N186_09270 55adcd52d3fa57d29ab4f7e585012593 133 Pfam PF01850 PIN domain 16 113 3.7E-6 T 31-10-2018 IPR002716 PIN domain N186_09270 55adcd52d3fa57d29ab4f7e585012593 133 Gene3D G3DSA:3.40.50.1010 1 131 2.0E-27 T 31-10-2018 N186_09270 55adcd52d3fa57d29ab4f7e585012593 133 SUPERFAMILY SSF88723 1 122 3.64E-11 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_08770 115f3665a1c6239e419e180bd17db997 132 PIRSF PIRSF014972 1 130 1.3E-29 T 31-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase N186_08770 115f3665a1c6239e419e180bd17db997 132 Gene3D G3DSA:3.10.129.10 1 129 1.4E-32 T 31-10-2018 N186_08770 115f3665a1c6239e419e180bd17db997 132 SUPERFAMILY SSF54637 4 125 1.15E-32 T 31-10-2018 IPR029069 HotDog domain superfamily N186_08770 115f3665a1c6239e419e180bd17db997 132 Pfam PF03061 Thioesterase superfamily 28 101 1.8E-5 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 N186_03780 0d87b844e3ad1a3b48a56d850203c521 103 Gene3D G3DSA:3.30.780.10 25 103 1.3E-28 T 31-10-2018 N186_03780 0d87b844e3ad1a3b48a56d850203c521 103 Pfam PF01253 Translation initiation factor SUI1 25 96 1.3E-23 T 31-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 N186_03780 0d87b844e3ad1a3b48a56d850203c521 103 SUPERFAMILY SSF55159 23 101 1.7E-25 T 31-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 N186_03780 0d87b844e3ad1a3b48a56d850203c521 103 PIRSF PIRSF037511 3 102 1.6E-24 T 31-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 N186_05525 9f71b500e914afd7cc7f63acc03adcdc 108 Gene3D G3DSA:3.40.50.10580 1 107 9.0E-6 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_05525 9f71b500e914afd7cc7f63acc03adcdc 108 SUPERFAMILY SSF159468 2 101 5.49E-6 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_01225 a09da18bc01ff59bf729f4bcc8174a2f 239 Gene3D G3DSA:3.40.50.1580 3 238 1.3E-70 T 31-10-2018 N186_01225 a09da18bc01ff59bf729f4bcc8174a2f 239 SUPERFAMILY SSF53167 4 234 5.76E-68 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 N186_01225 a09da18bc01ff59bf729f4bcc8174a2f 239 Pfam PF01048 Phosphorylase superfamily 17 234 6.9E-41 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 N186_01530 43db317dd4d015a2bb347411297b7705 253 Pfam PF00005 ABC transporter 26 171 4.3E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_01530 43db317dd4d015a2bb347411297b7705 253 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_01530 43db317dd4d015a2bb347411297b7705 253 Gene3D G3DSA:3.40.50.300 2 239 1.2E-52 T 31-10-2018 N186_01530 43db317dd4d015a2bb347411297b7705 253 SMART SM00382 34 218 7.4E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01530 43db317dd4d015a2bb347411297b7705 253 SUPERFAMILY SSF52540 5 230 9.12E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08200 6f2da7bd93f847d1b75716ffd2d0c5a2 314 SUPERFAMILY SSF53756 22 308 1.83E-31 T 31-10-2018 N186_08200 6f2da7bd93f847d1b75716ffd2d0c5a2 314 Pfam PF00534 Glycosyl transferases group 1 143 254 4.0E-9 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 N186_08200 6f2da7bd93f847d1b75716ffd2d0c5a2 314 Gene3D G3DSA:3.40.50.2000 11 141 8.2E-11 T 31-10-2018 N186_08200 6f2da7bd93f847d1b75716ffd2d0c5a2 314 Gene3D G3DSA:3.40.50.2000 142 295 1.7E-11 T 31-10-2018 N186_09670 8595d4433d3eb6cedd67ebf9192d380f 259 Gene3D G3DSA:3.40.50.1820 2 258 3.4E-63 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_09670 8595d4433d3eb6cedd67ebf9192d380f 259 Pfam PF12697 Alpha/beta hydrolase family 29 250 1.8E-21 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_09670 8595d4433d3eb6cedd67ebf9192d380f 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 5.8E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_09670 8595d4433d3eb6cedd67ebf9192d380f 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 5.8E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_09670 8595d4433d3eb6cedd67ebf9192d380f 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 5.8E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_09670 8595d4433d3eb6cedd67ebf9192d380f 259 SUPERFAMILY SSF53474 4 257 1.12E-63 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_09670 8595d4433d3eb6cedd67ebf9192d380f 259 PRINTS PR00412 Epoxide hydrolase signature 33 51 3.2E-5 T 31-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 N186_09670 8595d4433d3eb6cedd67ebf9192d380f 259 PRINTS PR00412 Epoxide hydrolase signature 53 68 3.2E-5 T 31-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 N186_09670 8595d4433d3eb6cedd67ebf9192d380f 259 PRINTS PR00412 Epoxide hydrolase signature 97 110 3.2E-5 T 31-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 N186_02970 594268018c22b3412bb16bcd87f970e6 341 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 194 212 7.1E-11 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_02970 594268018c22b3412bb16bcd87f970e6 341 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 173 193 7.1E-11 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_02970 594268018c22b3412bb16bcd87f970e6 341 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 236 7.1E-11 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_02970 594268018c22b3412bb16bcd87f970e6 341 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 172 329 8.4E-16 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 N186_02970 594268018c22b3412bb16bcd87f970e6 341 Gene3D G3DSA:3.40.50.300 164 341 5.9E-45 T 31-10-2018 N186_02970 594268018c22b3412bb16bcd87f970e6 341 Pfam PF01926 50S ribosome-binding GTPase 173 291 7.0E-20 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 N186_02970 594268018c22b3412bb16bcd87f970e6 341 Gene3D G3DSA:1.20.120.1190 12 163 7.7E-33 T 31-10-2018 N186_02970 594268018c22b3412bb16bcd87f970e6 341 SUPERFAMILY SSF52540 170 337 7.91E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00010 2fffc1c8259514efdf8f1e3c4d3421fa 313 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 198 271 2.3E-19 T 31-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal N186_00010 2fffc1c8259514efdf8f1e3c4d3421fa 313 Gene3D G3DSA:3.40.50.970 24 199 8.9E-26 T 31-10-2018 N186_00010 2fffc1c8259514efdf8f1e3c4d3421fa 313 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 12 296 2.8E-132 T 31-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate N186_00010 2fffc1c8259514efdf8f1e3c4d3421fa 313 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 47 194 1.1E-30 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 N186_00010 2fffc1c8259514efdf8f1e3c4d3421fa 313 SUPERFAMILY SSF52518 11 257 2.62E-78 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold N186_08050 7ba961002a03004d0dda63443887c360 127 Gene3D G3DSA:1.20.120.330 8 127 1.1E-39 T 31-10-2018 N186_08050 7ba961002a03004d0dda63443887c360 127 Pfam PF05942 Archaeal PaREP1/PaREP8 family 6 118 2.3E-32 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_09120 1c4a8a35046b12b114ac23ff3698505c 183 Gene3D G3DSA:3.30.460.40 2 147 1.5E-6 T 31-10-2018 N186_09120 1c4a8a35046b12b114ac23ff3698505c 183 SUPERFAMILY SSF81301 6 143 1.31E-11 T 31-10-2018 N186_08950 73badb4fbd0ee1ef8c82d0a05a28ad97 306 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 299 1.5E-69 T 31-10-2018 IPR016040 NAD(P)-binding domain N186_08950 73badb4fbd0ee1ef8c82d0a05a28ad97 306 SUPERFAMILY SSF51735 3 302 1.51E-103 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_08950 73badb4fbd0ee1ef8c82d0a05a28ad97 306 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 3.3E-9 T 31-10-2018 N186_08950 73badb4fbd0ee1ef8c82d0a05a28ad97 306 PRINTS PR01713 Nucleotide sugar epimerase signature 270 287 3.3E-9 T 31-10-2018 N186_08950 73badb4fbd0ee1ef8c82d0a05a28ad97 306 PRINTS PR01713 Nucleotide sugar epimerase signature 208 223 3.3E-9 T 31-10-2018 N186_08950 73badb4fbd0ee1ef8c82d0a05a28ad97 306 Gene3D G3DSA:3.40.50.720 6 291 5.7E-109 T 31-10-2018 N186_08950 73badb4fbd0ee1ef8c82d0a05a28ad97 306 Gene3D G3DSA:3.90.25.10 170 300 5.7E-109 T 31-10-2018 N186_06725 d39e7f96a6abbfbb562a3578e0bc4712 154 Gene3D G3DSA:3.40.930.10 11 152 1.7E-45 T 31-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 N186_06725 d39e7f96a6abbfbb562a3578e0bc4712 154 SUPERFAMILY SSF55804 13 152 1.57E-29 T 31-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 N186_06725 d39e7f96a6abbfbb562a3578e0bc4712 154 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 56 72 - T 31-10-2018 IPR002178 PTS EIIA type-2 domain N186_06725 d39e7f96a6abbfbb562a3578e0bc4712 154 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 13 152 1.3E-26 T 31-10-2018 IPR002178 PTS EIIA type-2 domain N186_07735 f80928db85b996a62431e374a212bec8 228 Pfam PF09335 SNARE associated Golgi protein 40 166 1.1E-25 T 31-10-2018 IPR032816 SNARE associated Golgi protein N186_06950 7727534784eb3220d9d4a4fb30f6240e 467 Gene3D G3DSA:3.40.190.10 46 461 2.4E-50 T 31-10-2018 N186_06950 7727534784eb3220d9d4a4fb30f6240e 467 SUPERFAMILY SSF53850 54 460 5.69E-50 T 31-10-2018 N186_06950 7727534784eb3220d9d4a4fb30f6240e 467 Pfam PF13416 Bacterial extracellular solute-binding protein 77 389 1.5E-25 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein N186_07250 b1e423a810272ec6ed40f62a34f9d163 372 Pfam PF01435 Peptidase family M48 141 365 3.4E-37 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 N186_07250 b1e423a810272ec6ed40f62a34f9d163 372 Hamap MF_00188 Protease HtpX [htpX]. 74 365 24.125 T 31-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 N186_07250 b1e423a810272ec6ed40f62a34f9d163 372 Gene3D G3DSA:3.30.2010.10 139 224 7.4E-16 T 31-10-2018 N186_04695 bf985b94281ecae5ea0c2f710a20aac3 226 Pfam PF04493 Endonuclease V 28 215 2.0E-55 T 31-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 N186_04695 bf985b94281ecae5ea0c2f710a20aac3 226 Gene3D G3DSA:3.30.2170.10 10 226 2.9E-61 T 31-10-2018 N186_04695 bf985b94281ecae5ea0c2f710a20aac3 226 Hamap MF_00801 Endonuclease V [nfi]. 16 225 29.096 T 31-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 N186_06970 dee130cc7e3a21e4532e893c96ff06d7 423 Pfam PF07690 Major Facilitator Superfamily 32 253 7.7E-18 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_06970 dee130cc7e3a21e4532e893c96ff06d7 423 Pfam PF07690 Major Facilitator Superfamily 269 417 1.9E-10 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_06970 dee130cc7e3a21e4532e893c96ff06d7 423 Gene3D G3DSA:1.20.1250.20 3 421 1.2E-44 T 31-10-2018 N186_06970 dee130cc7e3a21e4532e893c96ff06d7 423 SUPERFAMILY SSF103473 16 422 4.71E-43 T 31-10-2018 IPR036259 MFS transporter superfamily N186_08145 7c96a7a9d2290adac5c7e429599cf0b9 165 Pfam PF01909 Nucleotidyltransferase domain 71 154 5.9E-15 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_08145 7c96a7a9d2290adac5c7e429599cf0b9 165 Gene3D G3DSA:3.30.460.10 63 154 5.2E-28 T 31-10-2018 N186_08145 7c96a7a9d2290adac5c7e429599cf0b9 165 SUPERFAMILY SSF81301 67 155 2.4E-23 T 31-10-2018 N186_01425 ff0c1eab12b4cb1de4390ed979dba858 245 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 12 204 4.8E-28 T 31-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase N186_01425 ff0c1eab12b4cb1de4390ed979dba858 245 SUPERFAMILY SSF100950 11 214 1.88E-25 T 31-10-2018 IPR037171 NagB/RpiA transferase-like N186_01425 ff0c1eab12b4cb1de4390ed979dba858 245 Gene3D G3DSA:3.40.50.10420 45 213 9.7E-14 T 31-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily N186_01880 6a710abd7474bfd09cacff03f156aac9 342 SUPERFAMILY SSF53448 3 275 1.03E-47 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_01880 6a710abd7474bfd09cacff03f156aac9 342 Gene3D G3DSA:3.90.550.10 2 227 1.4E-42 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_01880 6a710abd7474bfd09cacff03f156aac9 342 Pfam PF00535 Glycosyl transferase family 2 9 172 1.3E-20 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 N186_02920 b2d5598d7fa7d510986af722bfaa7a13 143 SUPERFAMILY SSF75689 107 142 1.96E-10 T 31-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 N186_02920 b2d5598d7fa7d510986af722bfaa7a13 143 Gene3D G3DSA:3.30.70.3150 42 131 5.8E-24 T 31-10-2018 N186_02920 b2d5598d7fa7d510986af722bfaa7a13 143 SMART SM00653 30 137 1.3E-31 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 N186_02920 b2d5598d7fa7d510986af722bfaa7a13 143 SUPERFAMILY SSF100966 8 110 1.96E-22 T 31-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 N186_02920 b2d5598d7fa7d510986af722bfaa7a13 143 Pfam PF01873 Domain found in IF2B/IF5 26 136 4.8E-29 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 N186_02920 b2d5598d7fa7d510986af722bfaa7a13 143 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 8 143 29.992 T 31-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 N186_00175 9a9aafe635e6ea36b2933c8fa7a7a52d 83 SMART SM00966 8 53 2.5E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_00175 9a9aafe635e6ea36b2933c8fa7a7a52d 83 SUPERFAMILY SSF89447 4 48 7.46E-11 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_00175 9a9aafe635e6ea36b2933c8fa7a7a52d 83 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 9 48 4.9E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_00175 9a9aafe635e6ea36b2933c8fa7a7a52d 83 Gene3D G3DSA:2.10.260.10 7 46 2.4E-11 T 31-10-2018 N186_00175 9a9aafe635e6ea36b2933c8fa7a7a52d 83 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 50 9.1E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_06620 75d2a62391c05b0d1195f42aaa979c40 164 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 22 157 2.2E-10 T 31-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06620 75d2a62391c05b0d1195f42aaa979c40 164 Gene3D G3DSA:1.20.120.1200 7 159 1.8E-8 T 31-10-2018 N186_02160 c44f444fc5c81c528badf5fd6a633373 401 SUPERFAMILY SSF54197 125 238 4.16E-5 T 31-10-2018 IPR036265 HIT-like superfamily N186_02160 c44f444fc5c81c528badf5fd6a633373 401 Gene3D G3DSA:3.30.428.10 209 394 3.5E-30 T 31-10-2018 IPR036265 HIT-like superfamily N186_02160 c44f444fc5c81c528badf5fd6a633373 401 Pfam PF01230 HIT domain 274 359 1.9E-4 T 31-10-2018 IPR001310 Histidine triad (HIT) protein N186_02160 c44f444fc5c81c528badf5fd6a633373 401 SUPERFAMILY SSF54197 259 395 7.11E-23 T 31-10-2018 IPR036265 HIT-like superfamily N186_09060 2b115c8f1f622f58610b740fe7316034 289 Pfam PF00005 ABC transporter 28 181 1.0E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09060 2b115c8f1f622f58610b740fe7316034 289 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_09060 2b115c8f1f622f58610b740fe7316034 289 Gene3D G3DSA:3.40.50.300 7 274 5.1E-67 T 31-10-2018 N186_09060 2b115c8f1f622f58610b740fe7316034 289 SUPERFAMILY SSF52540 9 240 1.27E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09060 2b115c8f1f622f58610b740fe7316034 289 SMART SM00382 37 229 2.4E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01350 3fed54eec8b8793c3550b6978e73cc25 357 Pfam PF13641 Glycosyltransferase like family 2 3 207 7.4E-14 T 31-10-2018 N186_01350 3fed54eec8b8793c3550b6978e73cc25 357 SUPERFAMILY SSF53448 2 220 6.88E-28 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_01350 3fed54eec8b8793c3550b6978e73cc25 357 Gene3D G3DSA:3.90.550.10 1 200 3.1E-23 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_01875 cf5dc38a86f41f99d28f4a15fcd67204 436 SUPERFAMILY SSF51971 7 435 1.41E-38 T 31-10-2018 N186_01875 cf5dc38a86f41f99d28f4a15fcd67204 436 Gene3D G3DSA:3.50.50.60 2 436 6.6E-121 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_01875 cf5dc38a86f41f99d28f4a15fcd67204 436 Pfam PF01593 Flavin containing amine oxidoreductase 16 295 3.0E-16 T 31-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 N186_09510 32de4066598ef9051623811a3e731351 298 SUPERFAMILY SSF53686 5 293 1.11E-58 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme N186_09510 32de4066598ef9051623811a3e731351 298 Gene3D G3DSA:3.40.50.1100 21 118 1.4E-63 T 31-10-2018 N186_09510 32de4066598ef9051623811a3e731351 298 Gene3D G3DSA:3.40.50.1100 5 292 1.4E-63 T 31-10-2018 N186_09510 32de4066598ef9051623811a3e731351 298 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 291 8.9E-55 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme N186_06615 486903a4f5f882ae64f32af50c95bf37 158 SUPERFAMILY SSF54862 32 132 7.74E-25 T 31-10-2018 N186_06615 486903a4f5f882ae64f32af50c95bf37 158 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_06615 486903a4f5f882ae64f32af50c95bf37 158 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_06615 486903a4f5f882ae64f32af50c95bf37 158 Gene3D G3DSA:3.30.70.3270 32 156 1.3E-25 T 31-10-2018 N186_06615 486903a4f5f882ae64f32af50c95bf37 158 Pfam PF13237 4Fe-4S dicluster domain 48 100 3.1E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_02380 514d7f440845638454349e8799281d32 104 SUPERFAMILY SSF47598 28 62 9.23E-7 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 N186_02380 514d7f440845638454349e8799281d32 104 Gene3D G3DSA:1.10.1220.10 30 60 1.5E-5 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 N186_02380 514d7f440845638454349e8799281d32 104 Pfam PF01402 Ribbon-helix-helix protein, copG family 28 62 2.3E-7 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 N186_05945 af91a43737761935860ddaea5259d164 234 SUPERFAMILY SSF56281 27 233 1.86E-8 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_05945 af91a43737761935860ddaea5259d164 234 Gene3D G3DSA:3.60.15.10 120 234 2.7E-5 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_05945 af91a43737761935860ddaea5259d164 234 Gene3D G3DSA:3.60.15.10 3 119 8.0E-10 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_00320 efaf8a2ed09ed2fcfb305097b0c82d2b 374 Gene3D G3DSA:3.30.360.10 209 312 9.9E-104 T 31-10-2018 N186_00320 efaf8a2ed09ed2fcfb305097b0c82d2b 374 Gene3D G3DSA:3.40.50.720 3 347 9.9E-104 T 31-10-2018 N186_00320 efaf8a2ed09ed2fcfb305097b0c82d2b 374 SUPERFAMILY SSF55347 204 309 3.4E-29 T 31-10-2018 N186_00320 efaf8a2ed09ed2fcfb305097b0c82d2b 374 Pfam PF01658 Myo-inositol-1-phosphate synthase 205 310 3.3E-22 T 31-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 N186_00320 efaf8a2ed09ed2fcfb305097b0c82d2b 374 SUPERFAMILY SSF51735 2 368 4.19E-38 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_01815 d5c856a4d57517b235baee9de478bba0 212 Pfam PF12804 MobA-like NTP transferase domain 5 154 2.8E-25 T 31-10-2018 IPR025877 MobA-like NTP transferase N186_01815 d5c856a4d57517b235baee9de478bba0 212 SUPERFAMILY SSF53448 4 197 1.84E-24 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_01815 d5c856a4d57517b235baee9de478bba0 212 Gene3D G3DSA:3.90.550.10 3 210 1.5E-41 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_03460 e24f56c34735dd967ff5a1070360131a 313 SUPERFAMILY SSF52540 77 303 8.52E-28 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03460 e24f56c34735dd967ff5a1070360131a 313 Pfam PF06745 KaiC 77 304 3.6E-55 T 31-10-2018 IPR014774 KaiC-like domain N186_03460 e24f56c34735dd967ff5a1070360131a 313 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 96 109 - T 31-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 N186_03460 e24f56c34735dd967ff5a1070360131a 313 Gene3D G3DSA:3.40.50.300 74 305 3.6E-40 T 31-10-2018 N186_09690 d3acee0e300147fddf26969d0b845ce7 324 SUPERFAMILY SSF51735 76 319 1.57E-79 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_09690 d3acee0e300147fddf26969d0b845ce7 324 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 80 260 5.0E-5 T 31-10-2018 N186_09690 d3acee0e300147fddf26969d0b845ce7 324 Gene3D G3DSA:3.40.50.720 70 321 5.5E-80 T 31-10-2018 N186_09690 d3acee0e300147fddf26969d0b845ce7 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 98 5.2E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09690 d3acee0e300147fddf26969d0b845ce7 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 167 5.2E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09690 d3acee0e300147fddf26969d0b845ce7 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 219 5.2E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09690 d3acee0e300147fddf26969d0b845ce7 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 283 303 5.2E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09690 d3acee0e300147fddf26969d0b845ce7 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 248 5.2E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09690 d3acee0e300147fddf26969d0b845ce7 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 250 267 5.2E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09690 d3acee0e300147fddf26969d0b845ce7 324 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 216 244 - T 31-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 N186_09690 d3acee0e300147fddf26969d0b845ce7 324 Pfam PF00106 short chain dehydrogenase 80 267 3.2E-62 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09690 d3acee0e300147fddf26969d0b845ce7 324 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 229 248 1.2E-16 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09690 d3acee0e300147fddf26969d0b845ce7 324 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 167 1.2E-16 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_09690 d3acee0e300147fddf26969d0b845ce7 324 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 209 217 1.2E-16 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_07945 2ba9bdf906e886627499db10abd88fa2 298 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 291 1.0E-68 T 31-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 N186_07945 2ba9bdf906e886627499db10abd88fa2 298 SUPERFAMILY SSF51735 1 285 2.28E-69 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_07945 2ba9bdf906e886627499db10abd88fa2 298 Pfam PF04321 RmlD substrate binding domain 1 292 1.6E-64 T 31-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 N186_07945 2ba9bdf906e886627499db10abd88fa2 298 Gene3D G3DSA:3.90.25.10 172 264 9.4E-81 T 31-10-2018 N186_07945 2ba9bdf906e886627499db10abd88fa2 298 Gene3D G3DSA:3.40.50.720 4 270 9.4E-81 T 31-10-2018 N186_05725 665cddca849cd38677a5480c2a167514 101 Pfam PF01022 Bacterial regulatory protein, arsR family 19 64 2.1E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_05725 665cddca849cd38677a5480c2a167514 101 Gene3D G3DSA:1.10.10.10 7 95 1.3E-16 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_05725 665cddca849cd38677a5480c2a167514 101 SUPERFAMILY SSF46785 5 93 3.54E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_05725 665cddca849cd38677a5480c2a167514 101 SMART SM00418 12 93 3.7E-12 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_01395 669cfc58f054deba692b8cfc75fc85aa 78 Pfam PF02597 ThiS family 8 78 8.2E-6 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 N186_01395 669cfc58f054deba692b8cfc75fc85aa 78 SUPERFAMILY SSF54285 5 78 4.67E-9 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp N186_01395 669cfc58f054deba692b8cfc75fc85aa 78 Gene3D G3DSA:3.10.20.30 2 78 3.0E-8 T 31-10-2018 IPR012675 Beta-grasp domain superfamily N186_06070 65e764f2196525b5dd7eaf4764cc4dbc 123 Gene3D G3DSA:2.10.260.10 44 85 1.2E-10 T 31-10-2018 N186_06070 65e764f2196525b5dd7eaf4764cc4dbc 123 SUPERFAMILY SSF89447 47 102 9.29E-12 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_06070 65e764f2196525b5dd7eaf4764cc4dbc 123 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 48 88 1.5E-15 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_06070 65e764f2196525b5dd7eaf4764cc4dbc 123 SMART SM00966 47 92 4.9E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_06070 65e764f2196525b5dd7eaf4764cc4dbc 123 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 48 90 1.2E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_06560 fbef47ca64b8cba8fdfd2e1543566bbb 236 Gene3D G3DSA:3.30.70.3270 26 122 1.9E-20 T 31-10-2018 N186_06560 fbef47ca64b8cba8fdfd2e1543566bbb 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_06560 fbef47ca64b8cba8fdfd2e1543566bbb 236 SUPERFAMILY SSF54862 30 109 2.93E-21 T 31-10-2018 N186_06560 fbef47ca64b8cba8fdfd2e1543566bbb 236 Pfam PF13237 4Fe-4S dicluster domain 42 100 1.6E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_06560 fbef47ca64b8cba8fdfd2e1543566bbb 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_07055 f5da83b9012e8466452736a57cb6d6c7 243 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_07055 f5da83b9012e8466452736a57cb6d6c7 243 SMART SM00382 28 209 2.2E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_07055 f5da83b9012e8466452736a57cb6d6c7 243 Gene3D G3DSA:3.40.50.300 1 243 7.3E-63 T 31-10-2018 N186_07055 f5da83b9012e8466452736a57cb6d6c7 243 Pfam PF00005 ABC transporter 19 161 2.3E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_07055 f5da83b9012e8466452736a57cb6d6c7 243 SUPERFAMILY SSF52540 5 224 2.17E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08785 eaba45019a8417a5d3338d36bfea5270 131 Gene3D G3DSA:1.10.10.10 1 126 1.1E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_08785 eaba45019a8417a5d3338d36bfea5270 131 SUPERFAMILY SSF46785 5 77 1.65E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_00450 b3696b12ac35079d81ee32798a141db7 585 SUPERFAMILY SSF58104 261 448 4.84E-7 T 31-10-2018 N186_08660 a37f4a6f4970a410bd4b384015a21998 228 Gene3D G3DSA:3.40.50.2020 11 228 2.2E-56 T 31-10-2018 N186_08660 a37f4a6f4970a410bd4b384015a21998 228 Pfam PF14681 Uracil phosphoribosyltransferase 14 228 1.1E-43 T 31-10-2018 N186_08660 a37f4a6f4970a410bd4b384015a21998 228 SUPERFAMILY SSF53271 13 227 2.13E-50 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_01285 09d1a4db3b34e1201b07a55430681c23 330 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 206 275 2.9E-9 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain N186_01285 09d1a4db3b34e1201b07a55430681c23 330 SUPERFAMILY SSF102114 8 268 2.16E-30 T 31-10-2018 N186_01285 09d1a4db3b34e1201b07a55430681c23 330 TIGRFAM TIGR04084 rSAM_AF0577: putative peptide-modifying radical SAM enzyme, AF0577 family 1 330 5.7E-138 T 31-10-2018 IPR023819 Peptide-modifying radical SAM enzyme putative, AF0577 N186_01285 09d1a4db3b34e1201b07a55430681c23 330 Gene3D G3DSA:3.20.20.70 5 308 3.5E-36 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_08965 b33e60f19c523f226d75e64c3d117d5d 227 Gene3D G3DSA:3.60.15.10 2 227 6.2E-67 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_08965 b33e60f19c523f226d75e64c3d117d5d 227 Pfam PF12706 Beta-lactamase superfamily domain 25 191 5.8E-24 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_08965 b33e60f19c523f226d75e64c3d117d5d 227 SMART SM00849 8 190 4.2E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_08965 b33e60f19c523f226d75e64c3d117d5d 227 SUPERFAMILY SSF56281 4 218 2.17E-34 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_08965 b33e60f19c523f226d75e64c3d117d5d 227 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 227 37.332 T 31-10-2018 IPR022877 Protein of unknown funcion UPF0173 N186_05900 4e59a12ccb9efb71e6dec447bc1bf7b4 136 Gene3D G3DSA:3.40.1350.10 7 132 1.6E-27 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 N186_05900 4e59a12ccb9efb71e6dec447bc1bf7b4 136 SUPERFAMILY SSF52980 13 119 2.68E-14 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_05900 4e59a12ccb9efb71e6dec447bc1bf7b4 136 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 15 111 4.0E-12 T 31-10-2018 IPR002732 Holliday junction resolvase Hjc N186_07670 6b927c7491c41ae0cdd009e7f6844eed 600 Pfam PF00501 AMP-binding enzyme 89 512 8.2E-40 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 N186_07670 6b927c7491c41ae0cdd009e7f6844eed 600 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 76 1.1E-15 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 N186_07670 6b927c7491c41ae0cdd009e7f6844eed 600 SUPERFAMILY SSF56801 13 585 1.7E-91 T 31-10-2018 N186_07670 6b927c7491c41ae0cdd009e7f6844eed 600 Gene3D G3DSA:3.30.300.30 506 585 5.4E-12 T 31-10-2018 N186_07670 6b927c7491c41ae0cdd009e7f6844eed 600 Pfam PF13193 AMP-binding enzyme C-terminal domain 522 586 1.5E-8 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain N186_07670 6b927c7491c41ae0cdd009e7f6844eed 600 Gene3D G3DSA:3.40.50.12780 61 505 2.4E-55 T 31-10-2018 N186_05735 b6394ad0e37b0b5eb49932e8fe545011 127 PIRSF PIRSF006456 1 127 1.0E-41 T 31-10-2018 IPR007256 Protein of unknown function DUF369 N186_05735 b6394ad0e37b0b5eb49932e8fe545011 127 Pfam PF04126 Cyclophilin-like 3 124 1.7E-46 T 31-10-2018 IPR025658 Cyclophilin TM1367-like domain N186_05735 b6394ad0e37b0b5eb49932e8fe545011 127 SUPERFAMILY SSF50891 4 127 2.54E-31 T 31-10-2018 IPR029000 Cyclophilin-like domain superfamily N186_05735 b6394ad0e37b0b5eb49932e8fe545011 127 Gene3D G3DSA:2.40.100.20 1 127 4.0E-45 T 31-10-2018 N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 Pfam PF01145 SPFH domain / Band 7 family 26 195 1.3E-32 T 31-10-2018 IPR001107 Band 7 domain N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 31-10-2018 IPR018080 Band 7/stomatin-like, conserved site N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 Gene3D G3DSA:3.30.479.30 50 181 1.0E-40 T 31-10-2018 N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 SMART SM00244 22 179 1.6E-54 T 31-10-2018 IPR001107 Band 7 domain N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 PRINTS PR00721 Stomatin signature 111 128 7.6E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 PRINTS PR00721 Stomatin signature 155 173 7.6E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 PRINTS PR00721 Stomatin signature 174 195 7.6E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 PRINTS PR00721 Stomatin signature 76 97 7.6E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 PRINTS PR00721 Stomatin signature 29 51 7.6E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 PRINTS PR00721 Stomatin signature 131 154 7.6E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 N186_05705 1a916539f9a9f00cd3141a4090e2acbf 290 SUPERFAMILY SSF117892 53 186 1.7E-37 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily N186_01675 c26fca864423fc375ad122c737d3595f 139 SUPERFAMILY SSF46785 1 61 8.0E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_01675 c26fca864423fc375ad122c737d3595f 139 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 2.6E-10 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_01675 c26fca864423fc375ad122c737d3595f 139 SMART SM00344 1 107 2.4E-38 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 N186_01675 c26fca864423fc375ad122c737d3595f 139 Gene3D G3DSA:1.10.10.10 1 52 1.9E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_01675 c26fca864423fc375ad122c737d3595f 139 Gene3D G3DSA:3.30.70.920 64 139 2.2E-16 T 31-10-2018 N186_01675 c26fca864423fc375ad122c737d3595f 139 SUPERFAMILY SSF54909 61 139 1.61E-13 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel N186_01675 c26fca864423fc375ad122c737d3595f 139 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 9.2E-13 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_01675 c26fca864423fc375ad122c737d3595f 139 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 9.2E-13 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_01675 c26fca864423fc375ad122c737d3595f 139 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 9.2E-13 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_01675 c26fca864423fc375ad122c737d3595f 139 Pfam PF01037 Lrp/AsnC ligand binding domain 67 136 1.4E-12 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain N186_07205 099507e95b567feddc7efeee72eb46cb 447 Gene3D G3DSA:3.20.20.460 6 446 2.0E-121 T 31-10-2018 IPR036655 Monomethylamine methyltransferase MtmB superfamily GO:0008168|GO:0032259 KEGG: 00680+2.1.1.248|MetaCyc: PWY-5247 N186_07205 099507e95b567feddc7efeee72eb46cb 447 Pfam PF05369 Monomethylamine methyltransferase MtmB 10 445 1.0E-68 T 31-10-2018 IPR008031 Monomethylamine methyltransferase MtmB GO:0008168|GO:0032259 KEGG: 00680+2.1.1.248|MetaCyc: PWY-5247 N186_07205 099507e95b567feddc7efeee72eb46cb 447 SUPERFAMILY SSF75098 7 444 2.09E-162 T 31-10-2018 IPR036655 Monomethylamine methyltransferase MtmB superfamily GO:0008168|GO:0032259 KEGG: 00680+2.1.1.248|MetaCyc: PWY-5247 N186_00495 ee59be187f90fd134dc532e5331c9455 237 Gene3D G3DSA:3.20.20.190 1 237 1.4E-67 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 N186_00495 ee59be187f90fd134dc532e5331c9455 237 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 10 228 3.4E-33 T 31-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 N186_00495 ee59be187f90fd134dc532e5331c9455 237 SUPERFAMILY SSF51695 5 233 4.71E-64 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 N186_02780 f71f302e4e422b1dec2d9712010ee1b8 107 SUPERFAMILY SSF47819 2 103 1.22E-24 T 31-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 N186_02780 f71f302e4e422b1dec2d9712010ee1b8 107 PIRSF PIRSF005053 1 107 3.7E-24 T 31-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) N186_02780 f71f302e4e422b1dec2d9712010ee1b8 107 Gene3D G3DSA:1.20.1250.40 1 107 4.8E-14 T 31-10-2018 IPR038324 Rpb4/RPC9 superfamily N186_02780 f71f302e4e422b1dec2d9712010ee1b8 107 Pfam PF03874 RNA polymerase Rpb4 15 106 6.3E-13 T 31-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 N186_08085 18a3d65963609a7603100d1376aa8388 84 SUPERFAMILY SSF89447 6 53 5.58E-10 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_08085 18a3d65963609a7603100d1376aa8388 84 SMART SM00966 4 49 4.1E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08085 18a3d65963609a7603100d1376aa8388 84 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 44 1.5E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08085 18a3d65963609a7603100d1376aa8388 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 14 46 2.1E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08085 18a3d65963609a7603100d1376aa8388 84 Gene3D G3DSA:2.10.260.10 2 42 2.2E-10 T 31-10-2018 N186_06870 0a129076c3930ee11ca2339795b2893d 291 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_06870 0a129076c3930ee11ca2339795b2893d 291 Pfam PF00005 ABC transporter 22 169 5.0E-33 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_06870 0a129076c3930ee11ca2339795b2893d 291 Gene3D G3DSA:3.40.50.300 2 245 2.4E-77 T 31-10-2018 N186_06870 0a129076c3930ee11ca2339795b2893d 291 SUPERFAMILY SSF52540 6 250 6.44E-83 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06870 0a129076c3930ee11ca2339795b2893d 291 SMART SM00382 31 219 1.1E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01260 72a3a0510eca7c9a7bbb2231c737f0e4 493 Pfam PF00005 ABC transporter 1 136 1.6E-16 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_01260 72a3a0510eca7c9a7bbb2231c737f0e4 493 SMART SM00382 260 442 1.9E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01260 72a3a0510eca7c9a7bbb2231c737f0e4 493 SMART SM00382 1 184 0.0024 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01260 72a3a0510eca7c9a7bbb2231c737f0e4 493 SUPERFAMILY SSF52540 226 451 6.14E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01260 72a3a0510eca7c9a7bbb2231c737f0e4 493 Pfam PF00005 ABC transporter 251 386 6.1E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_01260 72a3a0510eca7c9a7bbb2231c737f0e4 493 SUPERFAMILY SSF52540 1 199 3.1E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01260 72a3a0510eca7c9a7bbb2231c737f0e4 493 Gene3D G3DSA:3.40.50.300 220 457 5.7E-54 T 31-10-2018 N186_01260 72a3a0510eca7c9a7bbb2231c737f0e4 493 ProSitePatterns PS00211 ABC transporters family signature. 359 373 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_01260 72a3a0510eca7c9a7bbb2231c737f0e4 493 Gene3D G3DSA:3.40.50.300 1 206 4.1E-45 T 31-10-2018 N186_01625 e835b8018d12801129b59cc35e9e599d 171 SUPERFAMILY SSF51283 1 171 3.66E-41 T 31-10-2018 IPR036157 dUTPase-like superfamily N186_01625 e835b8018d12801129b59cc35e9e599d 171 Pfam PF00692 dUTPase 62 167 2.0E-16 T 31-10-2018 IPR029054 dUTPase-like N186_01625 e835b8018d12801129b59cc35e9e599d 171 Hamap MF_00146 dCTP deaminase [dcd]. 1 171 24.233 T 31-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 N186_01625 e835b8018d12801129b59cc35e9e599d 171 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 171 3.7E-46 T 31-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 N186_01625 e835b8018d12801129b59cc35e9e599d 171 Gene3D G3DSA:2.70.40.10 1 171 3.7E-44 T 31-10-2018 IPR036157 dUTPase-like superfamily N186_05595 a5e9d7cb5f2aa1acab0751f855f84026 547 Gene3D G3DSA:3.40.50.2000 303 489 1.4E-37 T 31-10-2018 N186_05595 a5e9d7cb5f2aa1acab0751f855f84026 547 Gene3D G3DSA:3.40.50.2000 5 268 2.8E-29 T 31-10-2018 N186_05595 a5e9d7cb5f2aa1acab0751f855f84026 547 SUPERFAMILY SSF53756 6 545 7.42E-55 T 31-10-2018 N186_05595 a5e9d7cb5f2aa1acab0751f855f84026 547 Pfam PF00534 Glycosyl transferases group 1 330 480 1.1E-23 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 N186_05595 a5e9d7cb5f2aa1acab0751f855f84026 547 Pfam PF08323 Starch synthase catalytic domain 6 236 1.1E-25 T 31-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 N186_05245 7d564bccd056e11f60731c00e71a671a 265 Gene3D G3DSA:3.40.50.620 5 262 1.1E-72 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_05245 7d564bccd056e11f60731c00e71a671a 265 Pfam PF02540 NAD synthase 15 257 3.3E-68 T 31-10-2018 IPR022310 NAD/GMP synthase N186_05245 7d564bccd056e11f60731c00e71a671a 265 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 8 260 50.08 T 31-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 N186_05245 7d564bccd056e11f60731c00e71a671a 265 TIGRFAM TIGR00552 nadE: NAD+ synthetase 11 260 1.7E-65 T 31-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 N186_05245 7d564bccd056e11f60731c00e71a671a 265 SUPERFAMILY SSF52402 2 259 2.33E-68 T 31-10-2018 N186_00520 a561ab06775992905b9ca610ec1b3b29 98 SUPERFAMILY SSF47598 1 38 4.78E-6 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 N186_00520 a561ab06775992905b9ca610ec1b3b29 98 Gene3D G3DSA:1.10.1220.10 3 39 1.2E-6 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 N186_04390 fc0140e73b97e95dcdf0bab4764e2a19 451 Gene3D G3DSA:3.30.70.2200 5 163 9.9E-42 T 31-10-2018 N186_04390 fc0140e73b97e95dcdf0bab4764e2a19 451 Gene3D G3DSA:3.90.600.20 166 261 9.8E-25 T 31-10-2018 N186_04390 fc0140e73b97e95dcdf0bab4764e2a19 451 Pfam PF08489 Domain of unknown function (DUF1743) 150 263 9.3E-29 T 31-10-2018 IPR013696 Domain of unknown function DUF1743 N186_04390 fc0140e73b97e95dcdf0bab4764e2a19 451 Gene3D G3DSA:2.40.50.1010 262 415 1.8E-46 T 31-10-2018 N186_04390 fc0140e73b97e95dcdf0bab4764e2a19 451 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 6 436 34.592 T 31-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 N186_00205 2c4bc12d4619c6c8be8d5612a1232f70 160 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 4 126 2.5E-22 T 31-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 N186_00205 2c4bc12d4619c6c8be8d5612a1232f70 160 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 4 124 1.8E-14 T 31-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC N186_00205 2c4bc12d4619c6c8be8d5612a1232f70 160 SUPERFAMILY SSF56784 1 144 2.0E-21 T 31-10-2018 IPR036412 HAD-like superfamily N186_00205 2c4bc12d4619c6c8be8d5612a1232f70 160 Gene3D G3DSA:3.40.50.1000 3 160 5.8E-31 T 31-10-2018 IPR023214 HAD superfamily N186_00205 2c4bc12d4619c6c8be8d5612a1232f70 160 Pfam PF12689 Acid Phosphatase 4 124 4.3E-13 T 31-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 N186_07910 a14625dfd220d02dbe68ac4508faed19 290 Pfam PF00261 Tropomyosin 20 167 7.1E-11 T 31-10-2018 IPR000533 Tropomyosin Reactome: R-HSA-390522|Reactome: R-HSA-445355 N186_07910 a14625dfd220d02dbe68ac4508faed19 290 Gene3D G3DSA:1.20.5.1070 114 177 2.1E-8 T 31-10-2018 N186_07910 a14625dfd220d02dbe68ac4508faed19 290 Gene3D G3DSA:1.20.5.340 19 110 4.2E-12 T 31-10-2018 N186_07910 a14625dfd220d02dbe68ac4508faed19 290 SUPERFAMILY SSF57997 25 168 2.39E-20 T 31-10-2018 N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 339 421 5.0E-27 T 31-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 SUPERFAMILY SSF50465 331 423 1.73E-28 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 8 423 58.536 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 Gene3D G3DSA:2.40.30.10 333 423 1.1E-26 T 31-10-2018 N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 SUPERFAMILY SSF50447 217 330 3.74E-37 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 Pfam PF00009 Elongation factor Tu GTP binding domain 14 213 4.5E-31 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 Gene3D G3DSA:2.40.30.10 218 332 1.5E-45 T 31-10-2018 N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 PRINTS PR00315 GTP-binding elongation factor signature 116 127 1.6E-12 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 PRINTS PR00315 GTP-binding elongation factor signature 154 163 1.6E-12 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 PRINTS PR00315 GTP-binding elongation factor signature 17 30 1.6E-12 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 PRINTS PR00315 GTP-binding elongation factor signature 100 110 1.6E-12 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 Gene3D G3DSA:3.40.50.300 8 217 9.0E-59 T 31-10-2018 N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 12 423 6.5E-191 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit N186_02540 5342a295ad784b53a119eac7ff5a01ef 423 SUPERFAMILY SSF52540 10 225 7.89E-47 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01655 a6a1c25eb27ec4f7daaad7582a42b7b9 325 SMART SM00382 36 242 7.1E-20 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_01655 a6a1c25eb27ec4f7daaad7582a42b7b9 325 SUPERFAMILY SSF52540 35 315 2.28E-69 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01655 a6a1c25eb27ec4f7daaad7582a42b7b9 325 Pfam PF00005 ABC transporter 27 185 2.2E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_01655 a6a1c25eb27ec4f7daaad7582a42b7b9 325 Gene3D G3DSA:3.40.50.300 4 325 7.0E-101 T 31-10-2018 N186_01655 a6a1c25eb27ec4f7daaad7582a42b7b9 325 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_01655 a6a1c25eb27ec4f7daaad7582a42b7b9 325 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 2.0E-27 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_01655 a6a1c25eb27ec4f7daaad7582a42b7b9 325 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 299 4.9E-18 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_08055 ec8b056fe288edb3505afadcaa5a6318 173 Pfam PF05942 Archaeal PaREP1/PaREP8 family 51 151 1.1E-15 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_02290 4166c17fc184ad612867b43e070faea1 80 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 31-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02290 4166c17fc184ad612867b43e070faea1 80 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 22.923 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02290 4166c17fc184ad612867b43e070faea1 80 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 59 1.0E-30 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02290 4166c17fc184ad612867b43e070faea1 80 PIRSF PIRSF005653 1 72 6.9E-34 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02290 4166c17fc184ad612867b43e070faea1 80 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 6.0E-14 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02290 4166c17fc184ad612867b43e070faea1 80 Gene3D G3DSA:1.10.10.60 1 65 2.5E-32 T 31-10-2018 N186_02290 4166c17fc184ad612867b43e070faea1 80 SUPERFAMILY SSF46924 1 63 3.4E-28 T 31-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 N186_02250 be3ff077365aa784fc794f48ae9a87f2 482 Gene3D G3DSA:3.90.1860.10 1 482 6.7E-206 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 N186_02250 be3ff077365aa784fc794f48ae9a87f2 482 Pfam PF01139 tRNA-splicing ligase RtcB 47 482 2.7E-166 T 31-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 N186_02250 be3ff077365aa784fc794f48ae9a87f2 482 SUPERFAMILY SSF103365 5 482 3.14E-175 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 N186_02250 be3ff077365aa784fc794f48ae9a87f2 482 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 47 76 - T 31-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 N186_05485 f7c062f87a15f8192e5ef9dc22e0f5be 213 Gene3D G3DSA:3.40.470.10 13 202 1.3E-65 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 N186_05485 f7c062f87a15f8192e5ef9dc22e0f5be 213 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 26 200 2.4E-67 T 31-10-2018 IPR005273 Uracil-DNA glycosylase family 4 N186_05485 f7c062f87a15f8192e5ef9dc22e0f5be 213 Pfam PF03167 Uracil DNA glycosylase superfamily 40 187 1.7E-41 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 N186_05485 f7c062f87a15f8192e5ef9dc22e0f5be 213 SMART SM00987 40 194 9.4E-30 T 31-10-2018 N186_05485 f7c062f87a15f8192e5ef9dc22e0f5be 213 SMART SM00986 40 194 9.4E-30 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 N186_05485 f7c062f87a15f8192e5ef9dc22e0f5be 213 SUPERFAMILY SSF52141 14 199 9.48E-54 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 N186_01500 7a8982251ae6d2652752d349448cdc4e 186 SUPERFAMILY SSF53335 18 127 9.8E-15 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_01500 7a8982251ae6d2652752d349448cdc4e 186 Gene3D G3DSA:3.40.50.150 6 145 2.4E-19 T 31-10-2018 N186_01500 7a8982251ae6d2652752d349448cdc4e 186 Pfam PF08241 Methyltransferase domain 22 109 1.2E-9 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 N186_00925 4852b68d3a67fc84d6f6cf060dafaebf 245 Pfam PF00005 ABC transporter 29 157 8.8E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00925 4852b68d3a67fc84d6f6cf060dafaebf 245 SUPERFAMILY SSF52540 4 235 6.97E-66 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00925 4852b68d3a67fc84d6f6cf060dafaebf 245 SMART SM00382 32 209 1.6E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00925 4852b68d3a67fc84d6f6cf060dafaebf 245 Gene3D G3DSA:3.40.50.300 2 234 1.2E-57 T 31-10-2018 N186_00925 4852b68d3a67fc84d6f6cf060dafaebf 245 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_01895 53682c73269c0bcc772f5a316039db0f 189 Pfam PF01944 Stage II sporulation protein M 12 177 2.7E-24 T 31-10-2018 IPR002798 Stage II sporulation protein M-like N186_05955 9bf51bb6524bd05faa87c1354690fc57 157 Gene3D G3DSA:3.40.50.150 1 129 6.5E-20 T 31-10-2018 N186_05955 9bf51bb6524bd05faa87c1354690fc57 157 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 78 84 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 N186_05955 9bf51bb6524bd05faa87c1354690fc57 157 SUPERFAMILY SSF53335 12 118 2.18E-20 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_05955 9bf51bb6524bd05faa87c1354690fc57 157 Pfam PF05175 Methyltransferase small domain 12 86 4.3E-10 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 N186_04120 6a93ab7a3903bfa08f544bc0e35b340e 327 SUPERFAMILY SSF52540 2 199 8.88E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04120 6a93ab7a3903bfa08f544bc0e35b340e 327 SMART SM00382 10 188 9.5E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04120 6a93ab7a3903bfa08f544bc0e35b340e 327 ProSitePatterns PS00211 ABC transporters family signature. 113 127 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_04120 6a93ab7a3903bfa08f544bc0e35b340e 327 Pfam PF00005 ABC transporter 3 141 2.2E-19 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_04120 6a93ab7a3903bfa08f544bc0e35b340e 327 Gene3D G3DSA:3.40.50.300 1 214 6.8E-40 T 31-10-2018 N186_02465 abe5167e8b415654238e2f8ca58ae3c4 426 SMART SM00382 15 142 1.1E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_02465 abe5167e8b415654238e2f8ca58ae3c4 426 Pfam PF13173 AAA domain 17 157 3.5E-23 T 31-10-2018 N186_02465 abe5167e8b415654238e2f8ca58ae3c4 426 Pfam PF13635 Domain of unknown function (DUF4143) 287 418 7.5E-8 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 N186_02465 abe5167e8b415654238e2f8ca58ae3c4 426 SUPERFAMILY SSF52540 9 249 1.76E-12 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06340 8a830490b80f3be00c8b81fc03940c5b 530 Pfam PF01409 tRNA synthetases class II core domain (F) 234 504 7.8E-79 T 31-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 N186_06340 8a830490b80f3be00c8b81fc03940c5b 530 Gene3D G3DSA:1.10.10.10 15 102 1.8E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_06340 8a830490b80f3be00c8b81fc03940c5b 530 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 15 507 34.466 T 31-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 N186_06340 8a830490b80f3be00c8b81fc03940c5b 530 Gene3D G3DSA:3.30.930.10 207 513 1.1E-94 T 31-10-2018 N186_06340 8a830490b80f3be00c8b81fc03940c5b 530 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 197 506 4.3E-96 T 31-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 N186_06340 8a830490b80f3be00c8b81fc03940c5b 530 SUPERFAMILY SSF55681 244 503 3.83E-60 T 31-10-2018 N186_07485 948e1c8593619d27b3b2fc55d97af2d2 225 Pfam PF00702 haloacid dehalogenase-like hydrolase 4 184 2.2E-6 T 31-10-2018 N186_07485 948e1c8593619d27b3b2fc55d97af2d2 225 Gene3D G3DSA:1.10.150.240 13 88 1.3E-42 T 31-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 N186_07485 948e1c8593619d27b3b2fc55d97af2d2 225 Gene3D G3DSA:3.40.50.1000 4 212 1.3E-42 T 31-10-2018 IPR023214 HAD superfamily N186_07485 948e1c8593619d27b3b2fc55d97af2d2 225 SUPERFAMILY SSF56784 4 212 7.06E-22 T 31-10-2018 IPR036412 HAD-like superfamily N186_03410 f459f2716f7893e1b62f13b7ba6f2a51 109 SUPERFAMILY SSF50249 34 107 1.24E-16 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_03410 f459f2716f7893e1b62f13b7ba6f2a51 109 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 7 108 1.5E-44 T 31-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03410 f459f2716f7893e1b62f13b7ba6f2a51 109 Pfam PF00366 Ribosomal protein S17 40 106 5.0E-18 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03410 f459f2716f7893e1b62f13b7ba6f2a51 109 Gene3D G3DSA:2.40.50.1000 2 109 1.5E-29 T 31-10-2018 N186_03410 f459f2716f7893e1b62f13b7ba6f2a51 109 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 41 106 1.0E-11 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03410 f459f2716f7893e1b62f13b7ba6f2a51 109 PRINTS PR00973 Ribosomal protein S17 family signature 53 76 2.9E-6 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03410 f459f2716f7893e1b62f13b7ba6f2a51 109 PRINTS PR00973 Ribosomal protein S17 family signature 86 96 2.9E-6 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03410 f459f2716f7893e1b62f13b7ba6f2a51 109 PRINTS PR00973 Ribosomal protein S17 family signature 96 103 2.9E-6 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_07510 206d25925e8ae6eb42cd66aab828b01d 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 251 264 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 N186_07510 206d25925e8ae6eb42cd66aab828b01d 311 Pfam PF00294 pfkB family carbohydrate kinase 9 294 8.1E-59 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB N186_07510 206d25925e8ae6eb42cd66aab828b01d 311 SUPERFAMILY SSF53613 7 298 1.14E-73 T 31-10-2018 IPR029056 Ribokinase-like N186_07510 206d25925e8ae6eb42cd66aab828b01d 311 Gene3D G3DSA:3.40.1190.20 4 310 1.7E-80 T 31-10-2018 IPR029056 Ribokinase-like N186_07510 206d25925e8ae6eb42cd66aab828b01d 311 PRINTS PR00990 Ribokinase signature 182 197 4.4E-11 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 N186_07510 206d25925e8ae6eb42cd66aab828b01d 311 PRINTS PR00990 Ribokinase signature 39 58 4.4E-11 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 N186_07510 206d25925e8ae6eb42cd66aab828b01d 311 PRINTS PR00990 Ribokinase signature 12 33 4.4E-11 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 N186_07510 206d25925e8ae6eb42cd66aab828b01d 311 PRINTS PR00990 Ribokinase signature 221 232 4.4E-11 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 N186_07510 206d25925e8ae6eb42cd66aab828b01d 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 44 68 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 N186_08450 6dbc7e7c65e2ebb4999d3bd4176883ef 438 Pfam PF13596 PAS domain 318 422 1.2E-16 T 31-10-2018 N186_08450 6dbc7e7c65e2ebb4999d3bd4176883ef 438 Gene3D G3DSA:3.30.450.20 332 426 1.0E-5 T 31-10-2018 N186_08450 6dbc7e7c65e2ebb4999d3bd4176883ef 438 Pfam PF01814 Hemerythrin HHE cation binding domain 88 225 8.4E-10 T 31-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 N186_08450 6dbc7e7c65e2ebb4999d3bd4176883ef 438 Pfam PF04282 Family of unknown function (DUF438) 11 77 6.7E-22 T 31-10-2018 IPR007380 Domain of unknown function DUF438 N186_04595 de20aca85c786579edc9b1d05f8a7e5e 332 Pfam PF01368 DHH family 21 164 5.7E-9 T 31-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 N186_04595 de20aca85c786579edc9b1d05f8a7e5e 332 SUPERFAMILY SSF64182 21 304 4.84E-33 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily N186_04595 de20aca85c786579edc9b1d05f8a7e5e 332 Gene3D G3DSA:3.90.1640.10 7 207 1.5E-21 T 31-10-2018 N186_04595 de20aca85c786579edc9b1d05f8a7e5e 332 Pfam PF02272 DHHA1 domain 216 305 6.9E-11 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 N186_00805 06d59ccdfb99465ec1dbc804982285e0 359 SUPERFAMILY SSF51604 118 348 2.23E-64 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily N186_00805 06d59ccdfb99465ec1dbc804982285e0 359 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 118 6.8E-10 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain N186_00805 06d59ccdfb99465ec1dbc804982285e0 359 Pfam PF13378 Enolase C-terminal domain-like 138 348 1.1E-46 T 31-10-2018 IPR029065 Enolase C-terminal domain-like N186_00805 06d59ccdfb99465ec1dbc804982285e0 359 SMART SM00922 135 231 3.2E-22 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal N186_00805 06d59ccdfb99465ec1dbc804982285e0 359 Gene3D G3DSA:3.20.20.120 110 344 2.1E-99 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily N186_00805 06d59ccdfb99465ec1dbc804982285e0 359 Gene3D G3DSA:3.30.390.10 3 109 2.1E-99 T 31-10-2018 IPR029017 Enolase-like, N-terminal N186_00805 06d59ccdfb99465ec1dbc804982285e0 359 SUPERFAMILY SSF54826 2 119 8.25E-24 T 31-10-2018 N186_00805 06d59ccdfb99465ec1dbc804982285e0 359 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 181 212 - T 31-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 N186_06695 b507262735cb5a9d705779e6cfc947cb 137 SUPERFAMILY SSF53062 4 126 4.97E-23 T 31-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 N186_06695 b507262735cb5a9d705779e6cfc947cb 137 Gene3D G3DSA:3.40.50.510 4 131 8.5E-26 T 31-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 N186_06695 b507262735cb5a9d705779e6cfc947cb 137 Pfam PF03610 PTS system fructose IIA component 6 116 8.6E-15 T 31-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 N186_07620 46f147a660d82673c8198bf046306a89 229 Gene3D G3DSA:2.30.110.10 127 228 1.8E-7 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 N186_07620 46f147a660d82673c8198bf046306a89 229 SUPERFAMILY SSF50475 143 215 1.08E-6 T 31-10-2018 N186_03470 e3a927ff5603ac91a3553bbaa088ac42 402 Gene3D G3DSA:1.10.3210.10 14 377 6.5E-68 T 31-10-2018 N186_03470 e3a927ff5603ac91a3553bbaa088ac42 402 Pfam PF01966 HD domain 60 146 4.5E-13 T 31-10-2018 IPR006674 HD domain N186_03470 e3a927ff5603ac91a3553bbaa088ac42 402 Gene3D G3DSA:1.20.1250.30 221 388 6.5E-68 T 31-10-2018 N186_03470 e3a927ff5603ac91a3553bbaa088ac42 402 SMART SM00471 56 169 4.3E-14 T 31-10-2018 IPR003607 HD/PDEase domain N186_03470 e3a927ff5603ac91a3553bbaa088ac42 402 SUPERFAMILY SSF109604 6 396 1.19E-72 T 31-10-2018 N186_07605 2380b04976dc447af76032aceed1a897 276 SMART SM00989 204 269 1.0E-10 T 31-10-2018 IPR004096 4-vinyl reductase, 4VR N186_07605 2380b04976dc447af76032aceed1a897 276 SUPERFAMILY SSF111126 134 265 2.25E-14 T 31-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily N186_07605 2380b04976dc447af76032aceed1a897 276 Gene3D G3DSA:3.30.1380.20 147 272 6.3E-14 T 31-10-2018 N186_07895 7a183451350bf920d5aef3b05380cdc4 226 SUPERFAMILY SSF160945 27 175 5.36E-5 T 31-10-2018 N186_04145 3f43c472aa4a4e0dee2440663635e85b 185 Gene3D G3DSA:3.40.920.10 3 183 1.3E-46 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 N186_04145 3f43c472aa4a4e0dee2440663635e85b 185 SUPERFAMILY SSF53323 4 182 5.1E-44 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 N186_04145 3f43c472aa4a4e0dee2440663635e85b 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 5 182 1.0E-51 T 31-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 N186_04145 3f43c472aa4a4e0dee2440663635e85b 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 178 1.1E-34 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 N186_00975 2e83209af4e2552fc1b5fa290d0356b5 180 Pfam PF07155 ECF-type riboflavin transporter, S component 6 122 2.2E-6 T 31-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 N186_06980 02fc284a92076158d69de234c8c81603 173 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 5 167 5.3E-39 T 31-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06980 02fc284a92076158d69de234c8c81603 173 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 173 23.65 T 31-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06980 02fc284a92076158d69de234c8c81603 173 SUPERFAMILY SSF53271 6 167 1.84E-46 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_06980 02fc284a92076158d69de234c8c81603 173 Pfam PF00156 Phosphoribosyl transferase domain 39 151 1.7E-22 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 N186_06980 02fc284a92076158d69de234c8c81603 173 Gene3D G3DSA:3.40.50.2020 1 173 7.8E-60 T 31-10-2018 N186_01690 e4aae6beb82b755b97c2ec934996bad5 353 Gene3D G3DSA:3.40.50.620 64 270 3.0E-20 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_01690 e4aae6beb82b755b97c2ec934996bad5 353 SUPERFAMILY SSF52402 63 260 2.79E-18 T 31-10-2018 N186_01690 e4aae6beb82b755b97c2ec934996bad5 353 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 91 263 2.0E-8 T 31-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 N186_08315 b1368f120ba91b0758a60e9fbfdb2db4 1111 Pfam PF03065 Glycosyl hydrolase family 57 7 484 2.1E-89 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 N186_08315 b1368f120ba91b0758a60e9fbfdb2db4 1111 SUPERFAMILY SSF88713 14 424 6.67E-65 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 N186_08315 b1368f120ba91b0758a60e9fbfdb2db4 1111 Gene3D G3DSA:2.60.40.1190 764 1007 2.4E-55 T 31-10-2018 N186_08315 b1368f120ba91b0758a60e9fbfdb2db4 1111 SUPERFAMILY SSF49344 766 1000 3.49E-59 T 31-10-2018 N186_08315 b1368f120ba91b0758a60e9fbfdb2db4 1111 Gene3D G3DSA:3.20.110.20 164 449 2.0E-29 T 31-10-2018 N186_08315 b1368f120ba91b0758a60e9fbfdb2db4 1111 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 767 1005 4.0E-71 T 31-10-2018 IPR019248 Glucodextranase-like, C-terminal N186_06730 acc5ca23fcbc6a6ace8dcb4f32e65dd0 243 Pfam PF00156 Phosphoribosyl transferase domain 105 219 5.5E-15 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 N186_06730 acc5ca23fcbc6a6ace8dcb4f32e65dd0 243 SUPERFAMILY SSF53271 104 240 1.44E-20 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_06730 acc5ca23fcbc6a6ace8dcb4f32e65dd0 243 Gene3D G3DSA:3.40.50.2020 66 243 8.5E-24 T 31-10-2018 N186_02655 91691c7faab055ce5d8deaa361b33ebf 206 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 2 190 5.2E-33 T 31-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 N186_04690 3c592ac054a453616df43d99c97b740c 227 Gene3D G3DSA:3.40.50.620 93 227 1.2E-31 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_04690 3c592ac054a453616df43d99c97b740c 227 Gene3D G3DSA:1.20.1270.90 4 92 1.6E-25 T 31-10-2018 N186_04690 3c592ac054a453616df43d99c97b740c 227 SUPERFAMILY SSF52374 92 223 6.76E-22 T 31-10-2018 N186_04690 3c592ac054a453616df43d99c97b740c 227 Pfam PF04010 Protein of unknown function (DUF357) 13 78 2.4E-17 T 31-10-2018 IPR023140 Domain of unknown function DUF357 N186_04690 3c592ac054a453616df43d99c97b740c 227 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 93 157 3.4E-15 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 N186_04690 3c592ac054a453616df43d99c97b740c 227 SUPERFAMILY SSF158372 10 80 7.46E-18 T 31-10-2018 IPR036809 AF1782-like superfamily N186_04690 3c592ac054a453616df43d99c97b740c 227 Pfam PF01467 Cytidylyltransferase-like 95 222 7.0E-12 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 N186_01420 3525e0b19202c903a71e4dc702fa8b61 178 PIRSF PIRSF005785 1 170 4.7E-44 T 31-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 N186_01420 3525e0b19202c903a71e4dc702fa8b61 178 SUPERFAMILY SSF55486 73 163 5.31E-11 T 31-10-2018 N186_01420 3525e0b19202c903a71e4dc702fa8b61 178 Gene3D G3DSA:3.40.390.10 1 167 3.8E-41 T 31-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 N186_01420 3525e0b19202c903a71e4dc702fa8b61 178 Pfam PF07998 Peptidase family M54 64 166 4.1E-27 T 31-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 N186_03830 9b3216d14d64870bd970b00d8773791c 185 Gene3D G3DSA:1.20.58.1030 66 174 2.6E-8 T 31-10-2018 N186_03830 9b3216d14d64870bd970b00d8773791c 185 Pfam PF05916 GINS complex protein 43 158 2.0E-5 T 31-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 N186_05880 46eddf22e2095b52bc4803815c2fa9b4 160 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 3 150 1.1E-33 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 N186_05880 46eddf22e2095b52bc4803815c2fa9b4 160 Gene3D G3DSA:3.50.20.10 1 151 2.2E-29 T 31-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 N186_05880 46eddf22e2095b52bc4803815c2fa9b4 160 SUPERFAMILY SSF56271 2 150 8.11E-30 T 31-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 N186_05880 46eddf22e2095b52bc4803815c2fa9b4 160 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 4 115 4.0E-10 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 N186_00985 ef4f92ea27549fd8b5a0ef5be171d4f6 435 SUPERFAMILY SSF52833 261 405 1.82E-13 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_00985 ef4f92ea27549fd8b5a0ef5be171d4f6 435 Gene3D G3DSA:3.40.30.10 253 407 7.4E-14 T 31-10-2018 N186_00985 ef4f92ea27549fd8b5a0ef5be171d4f6 435 Pfam PF13462 Thioredoxin 266 399 2.8E-10 T 31-10-2018 IPR012336 Thioredoxin-like fold N186_06145 1241738a35f0660870d23d2282f4e2f7 189 SUPERFAMILY SSF52972 4 184 1.83E-57 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like N186_06145 1241738a35f0660870d23d2282f4e2f7 189 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 182 6.1E-56 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 N186_06145 1241738a35f0660870d23d2282f4e2f7 189 Hamap MF_01405 dITP/XTP pyrophosphatase. 3 184 38.426 T 31-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 N186_06145 1241738a35f0660870d23d2282f4e2f7 189 Gene3D G3DSA:3.90.950.10 4 186 1.2E-61 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like N186_06145 1241738a35f0660870d23d2282f4e2f7 189 Pfam PF01725 Ham1 family 5 180 9.0E-50 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 N186_01410 3d53f3ef4e2d7cf1aca6af83d128fa3f 226 SUPERFAMILY SSF82114 93 224 1.73E-36 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 N186_01410 3d53f3ef4e2d7cf1aca6af83d128fa3f 226 SUPERFAMILY SSF46785 20 88 9.1E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_01410 3d53f3ef4e2d7cf1aca6af83d128fa3f 226 Pfam PF01982 Domain of unknown function DUF120 99 224 6.4E-36 T 31-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 N186_01410 3d53f3ef4e2d7cf1aca6af83d128fa3f 226 Gene3D G3DSA:2.40.30.30 90 225 1.4E-39 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 N186_01410 3d53f3ef4e2d7cf1aca6af83d128fa3f 226 Gene3D G3DSA:1.10.10.10 1 88 7.4E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_00395 666f0a982eb560a3233c48444c711977 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 8.3E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_00395 666f0a982eb560a3233c48444c711977 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 142 166 8.3E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_00395 666f0a982eb560a3233c48444c711977 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 59 81 8.3E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_00395 666f0a982eb560a3233c48444c711977 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 179 198 8.3E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_00395 666f0a982eb560a3233c48444c711977 256 Pfam PF01061 ABC-2 type transporter 9 221 3.0E-34 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 N186_00395 666f0a982eb560a3233c48444c711977 256 PIRSF PIRSF006648 2 256 3.8E-59 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_09740 89e5f2a33e0917baf6c56b7d4957b13b 82 SUPERFAMILY SSF54862 3 80 3.84E-10 T 31-10-2018 N186_09740 89e5f2a33e0917baf6c56b7d4957b13b 82 Pfam PF13459 4Fe-4S single cluster domain 6 77 1.2E-15 T 31-10-2018 N186_09740 89e5f2a33e0917baf6c56b7d4957b13b 82 Gene3D G3DSA:3.30.70.20 2 79 1.4E-17 T 31-10-2018 N186_05395 0f562a0b8fd4c25a9dbe28542bdd6e8c 143 Gene3D G3DSA:2.60.40.790 4 142 2.6E-20 T 31-10-2018 IPR008978 HSP20-like chaperone N186_05395 0f562a0b8fd4c25a9dbe28542bdd6e8c 143 Pfam PF00011 Hsp20/alpha crystallin family 47 136 8.6E-13 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain N186_05395 0f562a0b8fd4c25a9dbe28542bdd6e8c 143 SUPERFAMILY SSF49764 34 134 9.77E-17 T 31-10-2018 IPR008978 HSP20-like chaperone N186_02145 d2aba8a2239ac64a0bc0695faab2ee12 209 Hamap MF_00582 UPF0215 protein . 8 185 23.317 T 31-10-2018 IPR002802 Protein of unknown function DUF99 N186_02145 d2aba8a2239ac64a0bc0695faab2ee12 209 Pfam PF01949 Protein of unknown function DUF99 7 183 3.5E-62 T 31-10-2018 IPR002802 Protein of unknown function DUF99 N186_02145 d2aba8a2239ac64a0bc0695faab2ee12 209 PIRSF PIRSF006380 1 191 8.8E-46 T 31-10-2018 IPR002802 Protein of unknown function DUF99 N186_02145 d2aba8a2239ac64a0bc0695faab2ee12 209 Gene3D G3DSA:3.30.2170.10 4 187 1.6E-49 T 31-10-2018 N186_02145 d2aba8a2239ac64a0bc0695faab2ee12 209 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 63 181 9.0E-27 T 31-10-2018 IPR002802 Protein of unknown function DUF99 N186_07260 23d2d6e5a9e6b7449df8bda32f152baf 106 Pfam PF01850 PIN domain 13 100 2.4E-8 T 31-10-2018 IPR002716 PIN domain N186_07260 23d2d6e5a9e6b7449df8bda32f152baf 106 SUPERFAMILY SSF88723 4 105 3.01E-12 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_07260 23d2d6e5a9e6b7449df8bda32f152baf 106 Gene3D G3DSA:3.40.50.1010 6 105 1.4E-6 T 31-10-2018 N186_00125 82a2de12bdabbcf512c090ef271d2cc9 286 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 147 264 5.6E-16 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal N186_00125 82a2de12bdabbcf512c090ef271d2cc9 286 Gene3D G3DSA:3.30.70.1890 7 132 4.2E-7 T 31-10-2018 N186_00125 82a2de12bdabbcf512c090ef271d2cc9 286 Gene3D G3DSA:3.30.70.1900 138 266 4.4E-22 T 31-10-2018 N186_07540 e9200d249092d57237341fd084c844af 267 Pfam PF00583 Acetyltransferase (GNAT) family 15 106 4.5E-19 T 31-10-2018 IPR000182 GNAT domain N186_07540 e9200d249092d57237341fd084c844af 267 SUPERFAMILY SSF55729 8 112 5.08E-26 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase N186_07540 e9200d249092d57237341fd084c844af 267 Gene3D G3DSA:3.40.630.30 4 116 9.0E-26 T 31-10-2018 N186_07245 a30385214eaa66d343603fd068d3d29a 251 Gene3D G3DSA:3.20.20.410 2 249 1.4E-42 T 31-10-2018 IPR036520 UPF0759 superfamily N186_07245 a30385214eaa66d343603fd068d3d29a 251 Pfam PF01904 Protein of unknown function DUF72 17 243 3.6E-37 T 31-10-2018 IPR002763 Protein of unknown function DUF72 N186_07245 a30385214eaa66d343603fd068d3d29a 251 SUPERFAMILY SSF117396 4 245 2.35E-46 T 31-10-2018 IPR036520 UPF0759 superfamily N186_08070 c863fd3db9ad7a27c00dcacbdbfd4f2f 136 Pfam PF05942 Archaeal PaREP1/PaREP8 family 12 124 2.9E-32 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_08070 c863fd3db9ad7a27c00dcacbdbfd4f2f 136 Gene3D G3DSA:1.20.120.330 11 135 6.4E-41 T 31-10-2018 N186_02700 7f1660980536061fb378f3041f632399 118 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 66 92 5.7E-6 T 31-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_02700 7f1660980536061fb378f3041f632399 118 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 93 116 5.7E-6 T 31-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_02700 7f1660980536061fb378f3041f632399 118 Gene3D G3DSA:1.20.120.610 2 118 8.3E-9 T 31-10-2018 N186_02700 7f1660980536061fb378f3041f632399 118 SUPERFAMILY SSF81333 49 116 1.57E-8 T 31-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily N186_02700 7f1660980536061fb378f3041f632399 118 Pfam PF00137 ATP synthase subunit C 55 114 1.2E-6 T 31-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 N186_03465 a65e431af2b30820d41fec691ad86f24 518 Pfam PF04055 Radical SAM superfamily 218 378 4.6E-15 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_03465 a65e431af2b30820d41fec691ad86f24 518 SUPERFAMILY SSF102114 210 477 1.16E-33 T 31-10-2018 N186_03465 a65e431af2b30820d41fec691ad86f24 518 Gene3D G3DSA:3.80.30.20 211 429 1.4E-14 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe N186_03465 a65e431af2b30820d41fec691ad86f24 518 SMART SM00729 213 427 2.3E-22 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_00900 f18af88df5312031f018a7b04fdfe992 459 Gene3D G3DSA:3.10.620.30 233 389 6.7E-24 T 31-10-2018 N186_00900 f18af88df5312031f018a7b04fdfe992 459 SMART SM00460 318 379 1.2E-13 T 31-10-2018 IPR002931 Transglutaminase-like N186_00900 f18af88df5312031f018a7b04fdfe992 459 SUPERFAMILY SSF54001 244 391 6.03E-30 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily N186_00900 f18af88df5312031f018a7b04fdfe992 459 Pfam PF01841 Transglutaminase-like superfamily 272 377 5.4E-25 T 31-10-2018 IPR002931 Transglutaminase-like N186_02200 8e3ab7db565015f867582aeaff5c425c 169 SUPERFAMILY SSF55174 9 161 2.62E-29 T 31-10-2018 N186_02200 8e3ab7db565015f867582aeaff5c425c 169 SMART SM01390 5 103 1.9E-16 T 31-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 N186_02200 8e3ab7db565015f867582aeaff5c425c 169 Pfam PF01479 S4 domain 104 150 3.2E-17 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02200 8e3ab7db565015f867582aeaff5c425c 169 ProSitePatterns PS00632 Ribosomal protein S4 signature. 102 126 - T 31-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02200 8e3ab7db565015f867582aeaff5c425c 169 SMART SM00363 104 166 2.9E-13 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02200 8e3ab7db565015f867582aeaff5c425c 169 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 10 61 4.3E-5 T 31-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 N186_02200 8e3ab7db565015f867582aeaff5c425c 169 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 157 34.758 T 31-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 N186_02200 8e3ab7db565015f867582aeaff5c425c 169 Gene3D G3DSA:3.10.290.10 103 167 3.5E-18 T 31-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 N186_02200 8e3ab7db565015f867582aeaff5c425c 169 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 1.0E-68 T 31-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 Gene3D G3DSA:3.20.110.20 1 352 1.4E-118 T 31-10-2018 N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 SUPERFAMILY SSF88713 4 272 1.15E-54 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 Pfam PF09095 Domain of unknown function (DUF1926) 430 636 7.2E-14 T 31-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 Pfam PF09095 Domain of unknown function (DUF1926) 373 426 1.0E-12 T 31-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 SUPERFAMILY SSF74650 369 627 3.77E-23 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 287 353 1.0E-12 T 31-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 Pfam PF03065 Glycosyl hydrolase family 57 7 265 2.6E-37 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 Pfam PF09094 Domain of unknown function (DUF1925) 279 354 8.1E-33 T 31-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 SUPERFAMILY SSF88688 279 353 1.11E-22 T 31-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 Gene3D G3DSA:2.70.98.10 430 634 2.9E-17 T 31-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 N186_05600 4d6c0176d6ed32cb94658bd3e2d373c7 643 Gene3D G3DSA:2.70.98.10 368 429 1.1E-16 T 31-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 N186_04655 c928880509a3c7c4fc89e05d63db61ee 319 Pfam PF00753 Metallo-beta-lactamase superfamily 30 101 2.3E-7 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_04655 c928880509a3c7c4fc89e05d63db61ee 319 Hamap MF_01818 Ribonuclease BN [rbn]. 7 301 22.805 T 31-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 N186_04655 c928880509a3c7c4fc89e05d63db61ee 319 Pfam PF12706 Beta-lactamase superfamily domain 201 269 2.5E-7 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_04655 c928880509a3c7c4fc89e05d63db61ee 319 SUPERFAMILY SSF56281 8 301 1.35E-52 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_04655 c928880509a3c7c4fc89e05d63db61ee 319 Gene3D G3DSA:3.60.15.10 7 301 1.4E-56 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_02665 d2b627a6f0cda2d4e91cc8acb7f14343 1041 Gene3D G3DSA:3.40.50.300 44 250 2.2E-26 T 31-10-2018 N186_02665 d2b627a6f0cda2d4e91cc8acb7f14343 1041 Gene3D G3DSA:3.40.50.300 323 470 8.7E-20 T 31-10-2018 N186_02665 d2b627a6f0cda2d4e91cc8acb7f14343 1041 SMART SM00490 349 435 4.5E-9 T 31-10-2018 IPR001650 Helicase, C-terminal N186_02665 d2b627a6f0cda2d4e91cc8acb7f14343 1041 Pfam PF00270 DEAD/DEAH box helicase 56 227 7.9E-18 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 N186_02665 d2b627a6f0cda2d4e91cc8acb7f14343 1041 SMART SM00487 49 255 1.6E-18 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain N186_02665 d2b627a6f0cda2d4e91cc8acb7f14343 1041 Pfam PF00271 Helicase conserved C-terminal domain 335 433 3.5E-13 T 31-10-2018 IPR001650 Helicase, C-terminal N186_02665 d2b627a6f0cda2d4e91cc8acb7f14343 1041 SUPERFAMILY SSF52540 62 437 2.84E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09185 46f11989f66243d47c48a295b845872d 675 SUPERFAMILY SSF50969 43 372 1.26E-10 T 31-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like N186_02955 32946f8d92e75c2b9db25e8d5ca94822 256 Pfam PF01876 RNase P subunit p30 34 223 5.0E-17 T 31-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 N186_02955 32946f8d92e75c2b9db25e8d5ca94822 256 SUPERFAMILY SSF89550 27 216 6.67E-12 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 N186_02955 32946f8d92e75c2b9db25e8d5ca94822 256 Gene3D G3DSA:3.20.20.140 35 234 5.6E-17 T 31-10-2018 N186_09150 ea97d5b3f04deb118ffcfe851d7e11e5 88 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 46 3.7E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_09150 ea97d5b3f04deb118ffcfe851d7e11e5 88 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 45 2.7E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_09150 ea97d5b3f04deb118ffcfe851d7e11e5 88 SUPERFAMILY SSF89447 5 47 1.03E-9 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_09150 ea97d5b3f04deb118ffcfe851d7e11e5 88 Gene3D G3DSA:2.10.260.10 3 44 4.9E-7 T 31-10-2018 N186_09150 ea97d5b3f04deb118ffcfe851d7e11e5 88 SMART SM00966 6 51 1.4E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_07445 24adc024ab40ad89fbc3a551736ef226 353 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 34 348 3.0E-54 T 31-10-2018 IPR007184 Mannoside phosphorylase N186_07445 24adc024ab40ad89fbc3a551736ef226 353 SUPERFAMILY SSF75005 44 343 2.88E-31 T 31-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily N186_07445 24adc024ab40ad89fbc3a551736ef226 353 Gene3D G3DSA:2.115.10.20 4 353 2.7E-34 T 31-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily N186_01605 b7db94602e3ab86d1ef7179c001a8791 176 SUPERFAMILY SSF50324 5 173 7.46E-67 T 31-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 N186_01605 b7db94602e3ab86d1ef7179c001a8791 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 13 172 37.596 T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 N186_01605 b7db94602e3ab86d1ef7179c001a8791 176 Pfam PF00719 Inorganic pyrophosphatase 17 172 1.4E-57 T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 N186_01605 b7db94602e3ab86d1ef7179c001a8791 176 Gene3D G3DSA:3.90.80.10 2 173 1.1E-69 T 31-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 N186_01605 b7db94602e3ab86d1ef7179c001a8791 176 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 64 70 - T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 N186_03475 ee25f584e71d74dd59d7d36a5917129e 172 SUPERFAMILY SSF49764 76 167 1.96E-21 T 31-10-2018 IPR008978 HSP20-like chaperone N186_03475 ee25f584e71d74dd59d7d36a5917129e 172 Gene3D G3DSA:2.60.40.790 75 160 1.7E-21 T 31-10-2018 IPR008978 HSP20-like chaperone N186_03475 ee25f584e71d74dd59d7d36a5917129e 172 Pfam PF00011 Hsp20/alpha crystallin family 87 169 2.3E-11 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain N186_09195 3e6805572be10770b930e418ea453122 119 SUPERFAMILY SSF88697 1 118 1.16E-14 T 31-10-2018 IPR015947 PUA-like superfamily N186_09195 3e6805572be10770b930e418ea453122 119 Pfam PF01878 EVE domain 2 92 7.1E-7 T 31-10-2018 IPR002740 EVE domain N186_09195 3e6805572be10770b930e418ea453122 119 Gene3D G3DSA:3.10.590.10 1 113 2.3E-22 T 31-10-2018 N186_03855 806f99868aaeb484b7ced648ae3daaf5 235 Gene3D G3DSA:1.10.10.900 87 161 7.9E-32 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily N186_03855 806f99868aaeb484b7ced648ae3daaf5 235 SUPERFAMILY SSF89895 4 85 1.83E-22 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily N186_03855 806f99868aaeb484b7ced648ae3daaf5 235 SUPERFAMILY SSF109728 81 154 4.45E-24 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily N186_03855 806f99868aaeb484b7ced648ae3daaf5 235 Pfam PF09377 SBDS protein C-terminal domain 100 181 1.1E-16 T 31-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 N186_03855 806f99868aaeb484b7ced648ae3daaf5 235 Gene3D G3DSA:3.30.1250.10 8 85 1.1E-25 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily N186_03855 806f99868aaeb484b7ced648ae3daaf5 235 SUPERFAMILY SSF54980 156 228 1.46E-19 T 31-10-2018 IPR035647 EF-G domain III/V-like N186_03855 806f99868aaeb484b7ced648ae3daaf5 235 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 4 231 4.8E-69 T 31-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 N186_03855 806f99868aaeb484b7ced648ae3daaf5 235 Gene3D G3DSA:3.30.70.240 163 231 6.2E-24 T 31-10-2018 N186_03855 806f99868aaeb484b7ced648ae3daaf5 235 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 93 6.8E-24 T 31-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal N186_02690 c278aa15fe44f55f4ac52a9787280b82 498 Gene3D G3DSA:3.40.50.720 4 135 1.1E-41 T 31-10-2018 N186_02690 c278aa15fe44f55f4ac52a9787280b82 498 SUPERFAMILY SSF52210 315 478 6.28E-33 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_02690 c278aa15fe44f55f4ac52a9787280b82 498 SUPERFAMILY SSF51735 3 144 2.8E-36 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_02690 c278aa15fe44f55f4ac52a9787280b82 498 Pfam PF13380 CoA binding domain 14 139 3.9E-22 T 31-10-2018 IPR003781 CoA-binding GO:0048037 N186_02690 c278aa15fe44f55f4ac52a9787280b82 498 Gene3D G3DSA:3.40.50.261 312 482 4.5E-44 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_02690 c278aa15fe44f55f4ac52a9787280b82 498 Gene3D G3DSA:3.40.50.261 161 311 2.5E-60 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_02690 c278aa15fe44f55f4ac52a9787280b82 498 SMART SM00881 9 108 5.6E-33 T 31-10-2018 IPR003781 CoA-binding GO:0048037 N186_02690 c278aa15fe44f55f4ac52a9787280b82 498 SUPERFAMILY SSF52210 164 311 7.98E-45 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 N186_02690 c278aa15fe44f55f4ac52a9787280b82 498 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 172 308 3.9E-58 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain N186_07860 b6dd789dd0ca28a1313e8356b5385952 275 Pfam PF14712 Snapin/Pallidin 56 139 5.7E-7 T 31-10-2018 IPR028119 Snapin/Pallidin/Snn1 Reactome: R-HSA-432722 N186_07860 b6dd789dd0ca28a1313e8356b5385952 275 SUPERFAMILY SSF57997 33 147 3.92E-13 T 31-10-2018 N186_07860 b6dd789dd0ca28a1313e8356b5385952 275 Gene3D G3DSA:1.20.5.340 31 153 1.2E-15 T 31-10-2018 N186_02055 3948d1f308c9b27f0eb6abf91559d4af 385 Pfam PF03787 RAMP superfamily 22 374 2.4E-27 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein N186_02055 3948d1f308c9b27f0eb6abf91559d4af 385 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 19 374 2.3E-57 T 31-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 N186_06405 e8a907404e23f1066ed134eafd60128e 292 Pfam PF04055 Radical SAM superfamily 24 181 1.3E-11 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_06405 e8a907404e23f1066ed134eafd60128e 292 SMART SM00729 20 230 2.3E-4 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_06405 e8a907404e23f1066ed134eafd60128e 292 SUPERFAMILY SSF102114 18 228 1.05E-11 T 31-10-2018 N186_06405 e8a907404e23f1066ed134eafd60128e 292 Gene3D G3DSA:3.80.30.30 54 261 2.3E-12 T 31-10-2018 N186_02840 84a6e9946f828bb8651409efb6c27bdc 99 SUPERFAMILY SSF55257 5 95 1.96E-19 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_02840 84a6e9946f828bb8651409efb6c27bdc 99 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 22 94 9.2E-18 T 31-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 N186_02840 84a6e9946f828bb8651409efb6c27bdc 99 Gene3D G3DSA:3.30.1360.10 10 98 1.8E-21 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 N186_07495 fe1218962ec171ededd73f56e9800941 170 SUPERFAMILY SSF55469 10 170 1.02E-48 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 N186_07495 fe1218962ec171ededd73f56e9800941 170 Gene3D G3DSA:3.40.109.10 9 170 9.6E-48 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 N186_07495 fe1218962ec171ededd73f56e9800941 170 Pfam PF00881 Nitroreductase family 13 70 3.0E-19 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 N186_07495 fe1218962ec171ededd73f56e9800941 170 Pfam PF00881 Nitroreductase family 80 147 2.3E-6 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 SUPERFAMILY SSF52540 454 718 2.95E-79 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 SUPERFAMILY SSF52540 181 448 7.17E-75 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 SUPERFAMILY SSF50692 10 96 1.53E-29 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 ProSitePatterns PS00674 AAA-protein family signature. 598 616 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 SUPERFAMILY SSF54585 98 188 1.08E-18 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 223 352 4.9E-49 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 496 627 5.1E-48 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Gene3D G3DSA:1.10.8.60 629 701 1.7E-108 T 31-10-2018 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 723 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Gene3D G3DSA:2.40.40.20 8 98 3.2E-35 T 31-10-2018 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 SMART SM01073 14 98 1.2E-39 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 SMART SM01072 114 177 8.2E-17 T 31-10-2018 IPR004201 CDC48, domain 2 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Gene3D G3DSA:3.40.50.300 454 716 1.7E-108 T 31-10-2018 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Gene3D G3DSA:3.40.50.300 180 353 2.7E-72 T 31-10-2018 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 98 1.1E-33 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Gene3D G3DSA:3.10.330.10 101 179 8.6E-7 T 31-10-2018 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 ProSitePatterns PS00674 AAA-protein family signature. 323 341 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Gene3D G3DSA:1.10.8.60 354 449 4.4E-35 T 31-10-2018 N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 SMART SM00382 219 355 4.0E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 SMART SM00382 492 630 6.0E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_02525 0f3c1b5532266d2cd059430a6d3102cd 735 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 115 176 8.7E-17 T 31-10-2018 IPR004201 CDC48, domain 2 N186_05080 454c12f0b3421e3cdadad0fb05622d30 1714 SUPERFAMILY SSF49452 1579 1653 8.04E-5 T 31-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 N186_05080 454c12f0b3421e3cdadad0fb05622d30 1714 Gene3D G3DSA:2.60.40.1120 1587 1657 3.9E-7 T 31-10-2018 N186_00270 c2d614b70facc2bb3cb2998b7261af32 167 Gene3D G3DSA:1.20.120.330 41 166 3.2E-36 T 31-10-2018 N186_00270 c2d614b70facc2bb3cb2998b7261af32 167 Pfam PF05942 Archaeal PaREP1/PaREP8 family 40 154 1.8E-32 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_00080 07c53f0187a973f5df9a0222ed561d53 262 SUPERFAMILY SSF56235 14 182 1.7E-5 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_00080 07c53f0187a973f5df9a0222ed561d53 262 Gene3D G3DSA:3.60.20.10 17 243 1.9E-7 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_04305 c9c74957883f7109e8daa3253d4aacec 415 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 41 402 40.68 T 31-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 N186_04305 c9c74957883f7109e8daa3253d4aacec 415 Gene3D G3DSA:3.40.50.620 36 291 1.8E-90 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_04305 c9c74957883f7109e8daa3253d4aacec 415 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 289 299 4.2E-19 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 N186_04305 c9c74957883f7109e8daa3253d4aacec 415 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 174 193 4.2E-19 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 N186_04305 c9c74957883f7109e8daa3253d4aacec 415 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 245 266 4.2E-19 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 N186_04305 c9c74957883f7109e8daa3253d4aacec 415 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 121 137 4.2E-19 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 N186_04305 c9c74957883f7109e8daa3253d4aacec 415 Pfam PF00579 tRNA synthetases class I (W and Y) 108 383 1.5E-31 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_04305 c9c74957883f7109e8daa3253d4aacec 415 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 108 410 9.2E-81 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 N186_04305 c9c74957883f7109e8daa3253d4aacec 415 SUPERFAMILY SSF52374 41 395 2.5E-82 T 31-10-2018 N186_04305 c9c74957883f7109e8daa3253d4aacec 415 Gene3D G3DSA:1.10.240.10 292 401 4.3E-40 T 31-10-2018 N186_02175 41884560dc1a80c4d768012269885f6f 183 SUPERFAMILY SSF52540 7 151 1.83E-20 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02175 41884560dc1a80c4d768012269885f6f 183 Pfam PF00025 ADP-ribosylation factor family 7 146 9.5E-10 T 31-10-2018 IPR006689 Small GTPase superfamily, ARF/SAR type GO:0005525 N186_02175 41884560dc1a80c4d768012269885f6f 183 Gene3D G3DSA:3.40.50.300 3 177 3.6E-23 T 31-10-2018 N186_02295 7fc16549de2f1242fa1ddeadf5818198 132 Pfam PF00380 Ribosomal protein S9/S16 9 132 2.0E-32 T 31-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 N186_02295 7fc16549de2f1242fa1ddeadf5818198 132 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 132 32.795 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02295 7fc16549de2f1242fa1ddeadf5818198 132 SUPERFAMILY SSF54211 3 132 6.45E-35 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_02295 7fc16549de2f1242fa1ddeadf5818198 132 ProSitePatterns PS00360 Ribosomal protein S9 signature. 67 85 - T 31-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 N186_02295 7fc16549de2f1242fa1ddeadf5818198 132 Gene3D G3DSA:3.30.230.10 1 132 2.9E-47 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup N186_02295 7fc16549de2f1242fa1ddeadf5818198 132 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 4 132 3.3E-55 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_00375 b0ecc2fc9cd40e37350a396310fa48bf 469 Pfam PF05893 Acyl-CoA reductase (LuxC) 42 453 3.4E-39 T 31-10-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 N186_00375 b0ecc2fc9cd40e37350a396310fa48bf 469 Gene3D G3DSA:3.40.605.10 16 293 3.3E-7 T 31-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 N186_00375 b0ecc2fc9cd40e37350a396310fa48bf 469 SUPERFAMILY SSF53720 28 284 2.38E-9 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 7 297 1.1E-84 T 31-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 Pfam PF00557 Metallopeptidase family M24 9 291 1.4E-36 T 31-10-2018 IPR000994 Peptidase M24 N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 PRINTS PR00599 Methionine aminopeptidase-1 signature 82 98 9.0E-16 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 PRINTS PR00599 Methionine aminopeptidase-1 signature 149 161 9.0E-16 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 PRINTS PR00599 Methionine aminopeptidase-1 signature 182 194 9.0E-16 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 PRINTS PR00599 Methionine aminopeptidase-1 signature 57 70 9.0E-16 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 SUPERFAMILY SSF55920 5 297 9.42E-58 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 Gene3D G3DSA:1.10.10.10 201 275 4.4E-81 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 Gene3D G3DSA:3.90.230.10 13 289 4.4E-81 T 31-10-2018 N186_04705 a6737177f7ce2dfc6ab60114260415f0 309 SUPERFAMILY SSF46785 201 275 1.5E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_00655 af368324f3d49a34065c3acdf752e0b4 414 ProSitePatterns PS00216 Sugar transport proteins signature 1. 281 296 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 N186_00655 af368324f3d49a34065c3acdf752e0b4 414 SUPERFAMILY SSF103473 4 413 7.72E-84 T 31-10-2018 IPR036259 MFS transporter superfamily N186_00655 af368324f3d49a34065c3acdf752e0b4 414 Pfam PF07690 Major Facilitator Superfamily 15 367 3.4E-47 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_00655 af368324f3d49a34065c3acdf752e0b4 414 Gene3D G3DSA:1.20.1250.20 4 414 7.2E-83 T 31-10-2018 N186_06760 493c09cd82917ece5faa117d3a7db0c5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 452 464 2.2E-18 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_06760 493c09cd82917ece5faa117d3a7db0c5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 402 2.2E-18 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_06760 493c09cd82917ece5faa117d3a7db0c5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 406 417 2.2E-18 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_06760 493c09cd82917ece5faa117d3a7db0c5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 315 329 2.2E-18 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_06760 493c09cd82917ece5faa117d3a7db0c5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 428 445 2.2E-18 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_06760 493c09cd82917ece5faa117d3a7db0c5 501 Pfam PF00232 Glycosyl hydrolase family 1 105 479 4.6E-53 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_06760 493c09cd82917ece5faa117d3a7db0c5 501 Pfam PF00232 Glycosyl hydrolase family 1 21 76 8.9E-9 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_06760 493c09cd82917ece5faa117d3a7db0c5 501 SUPERFAMILY SSF51445 8 487 1.12E-116 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily N186_06760 493c09cd82917ece5faa117d3a7db0c5 501 Gene3D G3DSA:3.20.20.80 2 497 7.9E-134 T 31-10-2018 N186_00640 0c6348d45a20961303ed4e6d5e312693 362 Pfam PF01300 Telomere recombination 31 206 7.7E-59 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 N186_00640 0c6348d45a20961303ed4e6d5e312693 362 Gene3D G3DSA:3.40.50.11030 224 362 8.5E-38 T 31-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily N186_00640 0c6348d45a20961303ed4e6d5e312693 362 PIRSF PIRSF004930 8 362 4.7E-125 T 31-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 N186_00640 0c6348d45a20961303ed4e6d5e312693 362 Gene3D G3DSA:3.90.870.10 9 222 9.7E-87 T 31-10-2018 N186_00640 0c6348d45a20961303ed4e6d5e312693 362 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 16 217 2.6E-67 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 N186_00640 0c6348d45a20961303ed4e6d5e312693 362 SUPERFAMILY SSF55821 10 217 1.34E-68 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily N186_00640 0c6348d45a20961303ed4e6d5e312693 362 Pfam PF03481 Putative GTP-binding controlling metal-binding 210 357 1.9E-23 T 31-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain N186_00460 951065cfa839358be0288f8cf0e08472 254 SMART SM01133 13 226 5.6E-18 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_00460 951065cfa839358be0288f8cf0e08472 254 Pfam PF01791 DeoC/LacD family aldolase 28 226 9.9E-20 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_00460 951065cfa839358be0288f8cf0e08472 254 PIRSF PIRSF038992 1 254 5.1E-59 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 N186_00460 951065cfa839358be0288f8cf0e08472 254 SUPERFAMILY SSF51569 2 241 2.12E-49 T 31-10-2018 N186_00460 951065cfa839358be0288f8cf0e08472 254 Gene3D G3DSA:3.20.20.70 1 253 6.0E-64 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_09475 ccf9e9ac332d26a0f2db8aad91957692 269 SUPERFAMILY SSF53218 6 203 1.7E-40 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily N186_09475 ccf9e9ac332d26a0f2db8aad91957692 269 Gene3D G3DSA:3.40.980.10 5 174 5.6E-57 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily N186_09475 ccf9e9ac332d26a0f2db8aad91957692 269 Pfam PF00994 Probable molybdopterin binding domain 9 173 2.9E-38 T 31-10-2018 IPR001453 MoaB/Mog domain N186_09475 ccf9e9ac332d26a0f2db8aad91957692 269 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 5 169 3.7E-27 T 31-10-2018 IPR001453 MoaB/Mog domain N186_09475 ccf9e9ac332d26a0f2db8aad91957692 269 SMART SM00852 8 174 1.9E-39 T 31-10-2018 IPR001453 MoaB/Mog domain N186_09325 67d53fb94ee2bfff8dab0eb0bca40f1c 368 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 356 2.5E-29 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_09325 67d53fb94ee2bfff8dab0eb0bca40f1c 368 Gene3D G3DSA:1.10.3720.10 110 353 3.0E-28 T 31-10-2018 IPR035906 MetI-like superfamily N186_09325 67d53fb94ee2bfff8dab0eb0bca40f1c 368 SUPERFAMILY SSF161098 122 337 7.06E-30 T 31-10-2018 IPR035906 MetI-like superfamily N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 3 58 2.8E-24 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 79 132 0.006 T 31-10-2018 N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 SMART SM01386 1 58 7.0E-29 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 1 147 36.798 T 31-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 ProSitePatterns PS00362 Ribosomal protein S15 signature. 96 126 - T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 Pfam PF00312 Ribosomal protein S15 72 144 4.5E-18 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 SMART SM01387 69 147 1.4E-19 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 Gene3D G3DSA:1.10.287.10 81 147 4.4E-31 T 31-10-2018 N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 Gene3D G3DSA:1.10.8.1030 33 80 2.6E-21 T 31-10-2018 N186_03535 463ce6956f3bc9db4d590cc8a06219e5 148 SUPERFAMILY SSF47060 64 141 1.65E-23 T 31-10-2018 IPR009068 S15/NS1, RNA-binding N186_06195 9fed95eb07d554ff7d95b894b960a00e 259 SUPERFAMILY SSF56300 31 176 5.45E-18 T 31-10-2018 N186_06195 9fed95eb07d554ff7d95b894b960a00e 259 Gene3D G3DSA:3.60.21.10 26 183 1.2E-8 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_06195 9fed95eb07d554ff7d95b894b960a00e 259 PIRSF PIRSF000887 15 256 1.7E-58 T 31-10-2018 IPR024173 Phosphoesterase, MJ0037 N186_06195 9fed95eb07d554ff7d95b894b960a00e 259 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 28 253 4.7E-47 T 31-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like N186_06195 9fed95eb07d554ff7d95b894b960a00e 259 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 31 173 8.2E-8 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 481 785 1.6E-73 T 31-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 PIRSF PIRSF000854 3 789 4.8E-259 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 345 1.2E-120 T 31-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 SUPERFAMILY SSF52009 353 463 6.8E-33 T 31-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 9 785 0.0 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 Pfam PF00391 PEP-utilising enzyme, mobile domain 383 454 1.1E-24 T 31-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 683 701 - T 31-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 Gene3D G3DSA:3.30.470.20 197 354 5.3E-52 T 31-10-2018 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 Gene3D G3DSA:3.30.1490.20 4 196 4.1E-76 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 Gene3D G3DSA:3.20.20.60 487 785 2.6E-89 T 31-10-2018 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 SUPERFAMILY SSF51621 476 788 5.23E-88 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 Gene3D G3DSA:3.50.30.10 355 464 4.3E-41 T 31-10-2018 N186_04310 2a433a2ecfd0024e85240b98f5803dde 826 SUPERFAMILY SSF56059 5 378 1.65E-107 T 31-10-2018 N186_09310 96d72ca4a3816e60de81e03adf7e337e 77 SMART SM01152 12 72 8.4E-9 T 31-10-2018 IPR003746 Protein of unknown function DUF167 N186_09310 96d72ca4a3816e60de81e03adf7e337e 77 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 15 70 8.0E-17 T 31-10-2018 IPR003746 Protein of unknown function DUF167 N186_09310 96d72ca4a3816e60de81e03adf7e337e 77 SUPERFAMILY SSF69786 15 72 3.66E-16 T 31-10-2018 IPR036591 YggU-like superfamily N186_09310 96d72ca4a3816e60de81e03adf7e337e 77 Gene3D G3DSA:3.30.1200.10 2 77 3.5E-16 T 31-10-2018 IPR036591 YggU-like superfamily N186_01660 4037462b2585cb5488504c30cc59ffa9 479 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 293 477 1.6E-19 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_01660 4037462b2585cb5488504c30cc59ffa9 479 SUPERFAMILY SSF161098 281 460 5.1E-16 T 31-10-2018 IPR035906 MetI-like superfamily N186_01660 4037462b2585cb5488504c30cc59ffa9 479 Gene3D G3DSA:1.10.3720.10 266 478 7.1E-13 T 31-10-2018 IPR035906 MetI-like superfamily N186_03405 ddff01aada067caf4b57595f9b9fd251 94 SUPERFAMILY SSF101744 2 90 2.96E-23 T 31-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 N186_03405 ddff01aada067caf4b57595f9b9fd251 94 SMART SM00538 2 94 8.6E-23 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 N186_03405 ddff01aada067caf4b57595f9b9fd251 94 Gene3D G3DSA:2.30.30.210 1 93 8.0E-30 T 31-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 N186_03405 ddff01aada067caf4b57595f9b9fd251 94 Pfam PF01868 Domain of unknown function UPF0086 7 89 4.3E-19 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 N186_03405 ddff01aada067caf4b57595f9b9fd251 94 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 10 88 18.215 T 31-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 N186_06675 495ca2d0afc7837861bb2c920c788f19 609 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 3 608 6.2E-153 T 31-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 N186_06675 495ca2d0afc7837861bb2c920c788f19 609 Gene3D G3DSA:3.40.50.10490 249 608 1.3E-98 T 31-10-2018 N186_06675 495ca2d0afc7837861bb2c920c788f19 609 Gene3D G3DSA:3.40.50.10490 443 595 1.3E-98 T 31-10-2018 N186_06675 495ca2d0afc7837861bb2c920c788f19 609 Pfam PF13522 Glutamine amidotransferase domain 65 194 1.4E-15 T 31-10-2018 N186_06675 495ca2d0afc7837861bb2c920c788f19 609 SUPERFAMILY SSF56235 3 228 5.66E-46 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_06675 495ca2d0afc7837861bb2c920c788f19 609 Pfam PF01380 SIS domain 462 588 7.9E-12 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 N186_06675 495ca2d0afc7837861bb2c920c788f19 609 Pfam PF01380 SIS domain 287 413 1.3E-24 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 N186_06675 495ca2d0afc7837861bb2c920c788f19 609 Gene3D G3DSA:3.60.20.10 3 238 7.5E-54 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_06675 495ca2d0afc7837861bb2c920c788f19 609 SUPERFAMILY SSF53697 247 608 3.03E-83 T 31-10-2018 N186_09375 f977ca03e4b931e446f547adad765bbb 151 SUPERFAMILY SSF88723 6 145 2.0E-14 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_09375 f977ca03e4b931e446f547adad765bbb 151 Pfam PF01850 PIN domain 6 140 9.5E-10 T 31-10-2018 IPR002716 PIN domain N186_09375 f977ca03e4b931e446f547adad765bbb 151 Gene3D G3DSA:3.40.50.1010 5 141 6.1E-7 T 31-10-2018 N186_06250 03771300aed6efca19a05b6b99fc796b 74 Gene3D G3DSA:1.10.10.1100 1 52 1.1E-14 T 31-10-2018 N186_06250 03771300aed6efca19a05b6b99fc796b 74 Pfam PF04324 BFD-like [2Fe-2S] binding domain 1 40 2.9E-6 T 31-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain N186_07715 e4122b34e7c73413de6dc5942c226b54 158 Gene3D G3DSA:1.20.1260.10 11 156 9.5E-7 T 31-10-2018 IPR012347 Ferritin-like N186_07715 e4122b34e7c73413de6dc5942c226b54 158 SUPERFAMILY SSF47240 10 156 1.89E-7 T 31-10-2018 IPR009078 Ferritin-like superfamily N186_08845 aa7925e44a2a726bffaa76d8911d1e52 425 PIRSF PIRSF006060 2 425 1.3E-82 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 N186_08845 aa7925e44a2a726bffaa76d8911d1e52 425 Pfam PF13520 Amino acid permease 13 392 9.6E-52 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 N186_08845 aa7925e44a2a726bffaa76d8911d1e52 425 Gene3D G3DSA:1.20.1740.10 9 425 1.2E-108 T 31-10-2018 N186_08605 8319daf7e30022480fd88bba7815f409 467 Pfam PF03008 Archaea bacterial proteins of unknown function 320 405 3.2E-21 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal N186_08605 8319daf7e30022480fd88bba7815f409 467 SUPERFAMILY SSF52980 354 443 5.9E-7 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_08605 8319daf7e30022480fd88bba7815f409 467 Gene3D G3DSA:3.40.50.300 84 177 9.7E-17 T 31-10-2018 N186_08605 8319daf7e30022480fd88bba7815f409 467 Gene3D G3DSA:3.40.50.300 7 83 6.0E-11 T 31-10-2018 N186_08605 8319daf7e30022480fd88bba7815f409 467 SUPERFAMILY SSF52540 11 251 1.28E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08605 8319daf7e30022480fd88bba7815f409 467 Pfam PF01637 ATPase domain predominantly from Archaea 92 211 3.2E-12 T 31-10-2018 IPR011579 ATPase domain GO:0005524 N186_08605 8319daf7e30022480fd88bba7815f409 467 Pfam PF01637 ATPase domain predominantly from Archaea 14 59 5.9E-9 T 31-10-2018 IPR011579 ATPase domain GO:0005524 N186_08425 67e7220fc6a68836e4a35a0a83b00387 219 Gene3D G3DSA:1.10.1240.10 2 84 6.4E-26 T 31-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 N186_08425 67e7220fc6a68836e4a35a0a83b00387 219 SUPERFAMILY SSF47644 6 84 3.27E-22 T 31-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 N186_08425 67e7220fc6a68836e4a35a0a83b00387 219 SMART SM01018 2 85 1.8E-29 T 31-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 N186_08425 67e7220fc6a68836e4a35a0a83b00387 219 Pfam PF02310 B12 binding domain 93 204 7.9E-28 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 N186_08425 67e7220fc6a68836e4a35a0a83b00387 219 Gene3D G3DSA:3.40.50.280 85 216 9.5E-46 T 31-10-2018 N186_08425 67e7220fc6a68836e4a35a0a83b00387 219 Pfam PF02607 B12 binding domain 6 77 1.4E-19 T 31-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 N186_08425 67e7220fc6a68836e4a35a0a83b00387 219 SUPERFAMILY SSF52242 72 214 5.63E-44 T 31-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 N186_04570 21039a8d2fecbdd9df2ccfae3aefbe9f 181 Pfam PF03367 ZPR1 zinc-finger domain 17 165 1.3E-29 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 N186_04570 21039a8d2fecbdd9df2ccfae3aefbe9f 181 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 18 166 4.0E-35 T 31-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 N186_04570 21039a8d2fecbdd9df2ccfae3aefbe9f 181 Gene3D G3DSA:2.60.120.1040 63 181 4.5E-15 T 31-10-2018 N186_04570 21039a8d2fecbdd9df2ccfae3aefbe9f 181 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 17 168 9.6E-35 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 N186_04570 21039a8d2fecbdd9df2ccfae3aefbe9f 181 SMART SM00709 16 167 9.3E-24 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 N186_03250 2f7ee32b86355d5feafcbd0e548ff4a0 103 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 4 102 16.187 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03250 2f7ee32b86355d5feafcbd0e548ff4a0 103 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 14 81 7.0E-11 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03250 2f7ee32b86355d5feafcbd0e548ff4a0 103 Gene3D G3DSA:3.30.70.330 2 102 3.6E-24 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily N186_03250 2f7ee32b86355d5feafcbd0e548ff4a0 103 SUPERFAMILY SSF54189 6 101 3.53E-22 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03250 2f7ee32b86355d5feafcbd0e548ff4a0 103 Pfam PF01282 Ribosomal protein S24e 24 99 2.7E-18 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_06365 612edad89de801569eb4963ac9b63c8e 262 Pfam PF01975 Survival protein SurE 3 187 6.9E-46 T 31-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 N186_06365 612edad89de801569eb4963ac9b63c8e 262 SUPERFAMILY SSF64167 2 252 4.05E-63 T 31-10-2018 N186_06365 612edad89de801569eb4963ac9b63c8e 262 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 259 30.011 T 31-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 N186_06365 612edad89de801569eb4963ac9b63c8e 262 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 2 236 1.9E-57 T 31-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 N186_06365 612edad89de801569eb4963ac9b63c8e 262 Gene3D G3DSA:3.40.1210.10 1 261 2.0E-76 T 31-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 N186_08290 55168c3edb4dc838ac01515b24e737ea 265 Pfam PF02361 Cobalt transport protein 12 226 2.5E-31 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 SUPERFAMILY SSF55060 178 318 1.6E-37 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 Hamap MF_00217 Mevalonate kinase [mvk]. 4 317 53.298 T 31-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 PIRSF PIRSF000530 215 318 2.5E-17 T 31-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 PIRSF PIRSF000530 1 197 1.2E-21 T 31-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 8 287 2.2E-85 T 31-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 Pfam PF08544 GHMP kinases C terminal 226 303 6.9E-18 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 Pfam PF00288 GHMP kinases N terminal domain 93 160 5.8E-20 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 Gene3D G3DSA:3.30.230.10 1 177 4.9E-53 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 SUPERFAMILY SSF54211 4 168 2.05E-45 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 100 111 - T 31-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 PRINTS PR00959 Mevalonate kinase family signature 8 32 1.1E-28 T 31-10-2018 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 PRINTS PR00959 Mevalonate kinase family signature 272 289 1.1E-28 T 31-10-2018 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 PRINTS PR00959 Mevalonate kinase family signature 98 120 1.1E-28 T 31-10-2018 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 PRINTS PR00959 Mevalonate kinase family signature 141 160 1.1E-28 T 31-10-2018 N186_05790 20193f75f0471e2d000e23c7701fe6b7 322 Gene3D G3DSA:3.30.70.890 178 314 3.5E-41 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily N186_09225 0219970bec7047f29012b66751c7dbc9 416 SUPERFAMILY SSF56281 3 403 3.33E-29 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_09225 0219970bec7047f29012b66751c7dbc9 416 Gene3D G3DSA:3.60.15.10 1 244 1.3E-28 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_09225 0219970bec7047f29012b66751c7dbc9 416 Pfam PF00753 Metallo-beta-lactamase superfamily 14 205 6.5E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_09225 0219970bec7047f29012b66751c7dbc9 416 SMART SM00849 14 210 2.3E-13 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_06105 06bfa94fae588b14bea1d1922ff778fb 296 Hamap MF_02040 Iron-sulfur cluster carrier protein. 26 277 35.298 T 31-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein N186_06105 06bfa94fae588b14bea1d1922ff778fb 296 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 30 276 4.6E-94 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 N186_06105 06bfa94fae588b14bea1d1922ff778fb 296 Gene3D G3DSA:3.40.50.300 15 275 2.5E-81 T 31-10-2018 N186_06105 06bfa94fae588b14bea1d1922ff778fb 296 ProSitePatterns PS01215 Mrp family signature. 139 155 - T 31-10-2018 IPR000808 Mrp, conserved site GO:0005524 N186_06105 06bfa94fae588b14bea1d1922ff778fb 296 SUPERFAMILY SSF52540 33 282 2.75E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_02535 f503fdfd271d5d26be86ee56a854b37b 163 Pfam PF03684 Uncharacterised protein family (UPF0179) 6 131 2.6E-20 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 N186_02535 f503fdfd271d5d26be86ee56a854b37b 163 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 6 125 3.0E-8 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 N186_03330 563a07845a2b87dfb3af860b10550b23 122 PIRSF PIRSF015730 12 122 7.0E-30 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 N186_03330 563a07845a2b87dfb3af860b10550b23 122 Pfam PF01984 Double-stranded DNA-binding domain 21 121 8.9E-24 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 N186_03330 563a07845a2b87dfb3af860b10550b23 122 SUPERFAMILY SSF46950 21 116 4.32E-25 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 N186_03330 563a07845a2b87dfb3af860b10550b23 122 Gene3D G3DSA:1.10.8.140 42 120 2.2E-25 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 N186_03330 563a07845a2b87dfb3af860b10550b23 122 Hamap MF_00026 DNA-binding protein . 16 120 16.311 T 31-10-2018 IPR022889 DNA-binding protein, archaeal N186_01180 5e6de7d98017e10860554bced9b465c2 194 SUPERFAMILY SSF46458 15 145 2.16E-11 T 31-10-2018 IPR009050 Globin-like superfamily N186_01180 5e6de7d98017e10860554bced9b465c2 194 Pfam PF11563 Protoglobin 16 133 5.8E-13 T 31-10-2018 N186_01180 5e6de7d98017e10860554bced9b465c2 194 Gene3D G3DSA:1.10.490.10 15 164 4.0E-16 T 31-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 N186_02765 1fd7894d3929544bcf21bac2263f6eb0 91 Gene3D G3DSA:1.10.60.20 1 62 2.1E-26 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02765 1fd7894d3929544bcf21bac2263f6eb0 91 SUPERFAMILY SSF116820 1 61 4.97E-21 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02765 1fd7894d3929544bcf21bac2263f6eb0 91 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 19.592 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02765 1fd7894d3929544bcf21bac2263f6eb0 91 Pfam PF00833 Ribosomal S17 1 61 5.5E-15 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_00870 6ae316113e929f5cf95b3d4c457dd8e1 300 SUPERFAMILY SSF53474 9 300 3.51E-53 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_00870 6ae316113e929f5cf95b3d4c457dd8e1 300 Gene3D G3DSA:3.40.50.1820 51 300 1.2E-43 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_00870 6ae316113e929f5cf95b3d4c457dd8e1 300 Pfam PF12146 Serine aminopeptidase, S33 75 194 3.0E-15 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 N186_03165 896d191b0f69fbc5870844d1e62452ff 133 Gene3D G3DSA:1.10.287.370 6 132 5.0E-26 T 31-10-2018 IPR009053 Prefoldin N186_03165 896d191b0f69fbc5870844d1e62452ff 133 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 7 130 8.2E-27 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 N186_03165 896d191b0f69fbc5870844d1e62452ff 133 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 1 133 12.34 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 N186_03165 896d191b0f69fbc5870844d1e62452ff 133 Pfam PF02996 Prefoldin subunit 20 128 3.3E-20 T 31-10-2018 IPR004127 Prefoldin alpha-like N186_03165 896d191b0f69fbc5870844d1e62452ff 133 SUPERFAMILY SSF46579 7 130 5.23E-21 T 31-10-2018 N186_09300 912d59dba88cd2b1badb4e108c241da5 118 Pfam PF01909 Nucleotidyltransferase domain 29 77 1.6E-10 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_09300 912d59dba88cd2b1badb4e108c241da5 118 SUPERFAMILY SSF81301 22 87 2.49E-12 T 31-10-2018 N186_09300 912d59dba88cd2b1badb4e108c241da5 118 Gene3D G3DSA:3.30.460.10 24 91 8.4E-11 T 31-10-2018 N186_03095 dadfbd67dc285f81b8fb6ee4603791a8 69 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 11 69 25.64 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 N186_03095 dadfbd67dc285f81b8fb6ee4603791a8 69 SUPERFAMILY SSF63393 4 68 9.42E-20 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 N186_03095 dadfbd67dc285f81b8fb6ee4603791a8 69 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 23 68 4.0E-7 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 N186_03095 dadfbd67dc285f81b8fb6ee4603791a8 69 SMART SM01389 9 69 2.1E-23 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 N186_03095 dadfbd67dc285f81b8fb6ee4603791a8 69 Gene3D G3DSA:2.20.28.90 9 69 1.6E-23 T 31-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily N186_03095 dadfbd67dc285f81b8fb6ee4603791a8 69 Pfam PF06093 Spt4/RpoE2 zinc finger 9 69 7.0E-14 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 N186_07570 7d71ba0fa1c3944792267567c5c73568 285 SUPERFAMILY SSF161111 8 203 9.55E-40 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily N186_07570 7d71ba0fa1c3944792267567c5c73568 285 Pfam PF16916 Dimerisation domain of Zinc Transporter 209 284 3.0E-23 T 31-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain N186_07570 7d71ba0fa1c3944792267567c5c73568 285 Pfam PF01545 Cation efflux family 11 197 4.7E-31 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 N186_07570 7d71ba0fa1c3944792267567c5c73568 285 Gene3D G3DSA:1.20.1510.10 8 201 2.4E-37 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily N186_07570 7d71ba0fa1c3944792267567c5c73568 285 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 9 284 2.9E-57 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 N186_07570 7d71ba0fa1c3944792267567c5c73568 285 SUPERFAMILY SSF160240 206 284 2.88E-19 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 N186_07570 7d71ba0fa1c3944792267567c5c73568 285 Gene3D G3DSA:3.30.70.1350 202 285 1.5E-23 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 N186_09705 bee5f0a599c41422d4f1ace470f1aba5 589 SUPERFAMILY SSF53474 26 266 1.07E-42 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_09705 bee5f0a599c41422d4f1ace470f1aba5 589 Gene3D G3DSA:3.40.50.1820 29 267 2.2E-41 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_09705 bee5f0a599c41422d4f1ace470f1aba5 589 Pfam PF12146 Serine aminopeptidase, S33 72 184 3.4E-11 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 N186_01680 a01f5608cc6b6a982e50a0cac721d729 476 SUPERFAMILY SSF50952 103 308 7.85E-5 T 31-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 N186_09500 2de62c7afa36ffb124cd970e8618a4f4 487 SUPERFAMILY SSF52402 152 384 5.23E-10 T 31-10-2018 N186_09500 2de62c7afa36ffb124cd970e8618a4f4 487 Gene3D G3DSA:3.40.50.620 150 373 1.6E-10 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold N186_02400 a4557ba5eec816e84248b1e0edef8872 150 SUPERFAMILY SSF51306 35 106 3.53E-10 T 31-10-2018 IPR036286 LexA/Signal peptidase-like superfamily N186_02400 a4557ba5eec816e84248b1e0edef8872 150 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 40 55 6.7E-5 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 N186_02400 a4557ba5eec816e84248b1e0edef8872 150 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 90 101 6.7E-5 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 N186_02400 a4557ba5eec816e84248b1e0edef8872 150 Gene3D G3DSA:2.10.109.10 26 121 1.1E-5 T 31-10-2018 N186_02400 a4557ba5eec816e84248b1e0edef8872 150 Pfam PF00717 Peptidase S24-like 40 103 1.1E-10 T 31-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C N186_02400 a4557ba5eec816e84248b1e0edef8872 150 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 9 127 2.3E-23 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 N186_02265 d1da392e38d8a67dfcd9084ff8513d28 364 Pfam PF01070 FMN-dependent dehydrogenase 179 342 1.3E-14 T 31-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 N186_02265 d1da392e38d8a67dfcd9084ff8513d28 364 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 10 347 1.1E-112 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 N186_02265 d1da392e38d8a67dfcd9084ff8513d28 364 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 7 348 38.699 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 N186_02265 d1da392e38d8a67dfcd9084ff8513d28 364 SUPERFAMILY SSF51395 29 359 1.37E-74 T 31-10-2018 N186_02265 d1da392e38d8a67dfcd9084ff8513d28 364 PIRSF PIRSF003314 4 358 1.6E-118 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 N186_02265 d1da392e38d8a67dfcd9084ff8513d28 364 Gene3D G3DSA:3.20.20.70 6 363 1.6E-120 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_02870 3cf53c2c21077bab0769a8df2b3fa64e 137 SUPERFAMILY SSF46785 17 87 1.35E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_02870 3cf53c2c21077bab0769a8df2b3fa64e 137 Pfam PF04182 B-block binding subunit of TFIIIC 27 91 5.6E-9 T 31-10-2018 IPR007309 B-block binding subunit of TFIIIC Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066 N186_02870 3cf53c2c21077bab0769a8df2b3fa64e 137 Gene3D G3DSA:1.10.10.10 26 88 2.5E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04985 eb6d6160554e0028624959100a71e6c8 239 SUPERFAMILY SSF52540 4 196 3.37E-28 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04985 eb6d6160554e0028624959100a71e6c8 239 Pfam PF13614 AAA domain 10 156 5.4E-12 T 31-10-2018 IPR025669 AAA domain N186_04985 eb6d6160554e0028624959100a71e6c8 239 Gene3D G3DSA:3.40.50.300 1 232 4.6E-31 T 31-10-2018 N186_09250 351eebadc5757117b8ea8ba87f0b92c1 256 Pfam PF03168 Late embryogenesis abundant protein 89 178 1.1E-6 T 31-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup N186_06835 108ac87cd5883ccb797874a73b9db20f 219 SUPERFAMILY SSF54292 7 103 4.33E-24 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 N186_06835 108ac87cd5883ccb797874a73b9db20f 219 SUPERFAMILY SSF46548 107 212 2.09E-16 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 N186_06835 108ac87cd5883ccb797874a73b9db20f 219 Gene3D G3DSA:1.10.1060.10 103 217 1.1E-18 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 N186_06835 108ac87cd5883ccb797874a73b9db20f 219 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 N186_06835 108ac87cd5883ccb797874a73b9db20f 219 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 134 145 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_06835 108ac87cd5883ccb797874a73b9db20f 219 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 208 5.3E-42 T 31-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 N186_06835 108ac87cd5883ccb797874a73b9db20f 219 Pfam PF13183 4Fe-4S dicluster domain 131 197 1.9E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_06835 108ac87cd5883ccb797874a73b9db20f 219 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 108 4.4E-28 T 31-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 N186_06835 108ac87cd5883ccb797874a73b9db20f 219 Gene3D G3DSA:3.10.20.30 1 102 9.4E-28 T 31-10-2018 IPR012675 Beta-grasp domain superfamily N186_05255 2e43f59cd9286c583c1fce8037041a14 243 Gene3D G3DSA:3.40.50.300 1 233 4.5E-59 T 31-10-2018 N186_05255 2e43f59cd9286c583c1fce8037041a14 243 SMART SM00382 27 210 4.9E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_05255 2e43f59cd9286c583c1fce8037041a14 243 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_05255 2e43f59cd9286c583c1fce8037041a14 243 SUPERFAMILY SSF52540 2 217 1.66E-54 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05255 2e43f59cd9286c583c1fce8037041a14 243 Pfam PF00005 ABC transporter 18 163 3.9E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_04155 9d4711aeda42a8c6bfb630e35db49c75 390 SUPERFAMILY SSF52922 258 387 5.37E-29 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 N186_04155 9d4711aeda42a8c6bfb630e35db49c75 390 Gene3D G3DSA:3.40.50.970 7 257 2.2E-85 T 31-10-2018 N186_04155 9d4711aeda42a8c6bfb630e35db49c75 390 Gene3D G3DSA:3.40.50.920 259 390 6.1E-31 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 N186_04155 9d4711aeda42a8c6bfb630e35db49c75 390 SUPERFAMILY SSF52518 7 256 3.14E-58 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold N186_04155 9d4711aeda42a8c6bfb630e35db49c75 390 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 268 371 5.3E-25 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II N186_04155 9d4711aeda42a8c6bfb630e35db49c75 390 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 21 242 4.2E-61 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 N186_00905 b04653d118cb30c5db815895f210e86b 221 Pfam PF00406 Adenylate kinase 8 188 1.5E-42 T 31-10-2018 N186_00905 b04653d118cb30c5db815895f210e86b 221 SUPERFAMILY SSF52540 6 197 8.31E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00905 b04653d118cb30c5db815895f210e86b 221 ProSitePatterns PS00113 Adenylate kinase signature. 84 95 - T 31-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_00905 b04653d118cb30c5db815895f210e86b 221 TIGRFAM TIGR01351 adk: adenylate kinase 6 200 2.0E-67 T 31-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 N186_00905 b04653d118cb30c5db815895f210e86b 221 Hamap MF_00235 Adenylate kinase [adk]. 4 211 41.552 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_00905 b04653d118cb30c5db815895f210e86b 221 PRINTS PR00094 Adenylate kinase signature 84 100 1.9E-28 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_00905 b04653d118cb30c5db815895f210e86b 221 PRINTS PR00094 Adenylate kinase signature 7 20 1.9E-28 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_00905 b04653d118cb30c5db815895f210e86b 221 PRINTS PR00094 Adenylate kinase signature 175 189 1.9E-28 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_00905 b04653d118cb30c5db815895f210e86b 221 PRINTS PR00094 Adenylate kinase signature 35 49 1.9E-28 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_00905 b04653d118cb30c5db815895f210e86b 221 PRINTS PR00094 Adenylate kinase signature 158 173 1.9E-28 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 N186_00905 b04653d118cb30c5db815895f210e86b 221 Pfam PF05191 Adenylate kinase, active site lid 125 160 2.3E-14 T 31-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 N186_00905 b04653d118cb30c5db815895f210e86b 221 Gene3D G3DSA:3.40.50.300 2 218 1.4E-71 T 31-10-2018 N186_05505 3bad09e6c43aaf1d9a0038d495222c65 276 SMART SM00989 204 269 2.5E-13 T 31-10-2018 IPR004096 4-vinyl reductase, 4VR N186_05505 3bad09e6c43aaf1d9a0038d495222c65 276 Gene3D G3DSA:3.30.1380.20 123 272 3.0E-11 T 31-10-2018 N186_05505 3bad09e6c43aaf1d9a0038d495222c65 276 SUPERFAMILY SSF111126 132 265 2.2E-14 T 31-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily N186_05505 3bad09e6c43aaf1d9a0038d495222c65 276 Pfam PF02830 V4R domain 206 266 2.3E-7 T 31-10-2018 IPR004096 4-vinyl reductase, 4VR N186_05505 3bad09e6c43aaf1d9a0038d495222c65 276 SUPERFAMILY SSF55021 23 101 6.62E-5 T 31-10-2018 N186_05505 3bad09e6c43aaf1d9a0038d495222c65 276 Gene3D G3DSA:3.30.70.260 25 103 6.6E-5 T 31-10-2018 N186_05350 548c328bbe70172d189a6e86aedb140f 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 50 113 3.5E-18 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal N186_05350 548c328bbe70172d189a6e86aedb140f 134 Gene3D G3DSA:1.10.12.20 10 52 5.5E-6 T 31-10-2018 N186_05350 548c328bbe70172d189a6e86aedb140f 134 SUPERFAMILY SSF50249 6 118 1.22E-33 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_05350 548c328bbe70172d189a6e86aedb140f 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 18 48 2.2E-9 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal N186_06020 396eb5e8bc9e8f7c009cfd7f0bddad73 100 Gene3D G3DSA:1.10.10.10 11 85 1.9E-15 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_06020 396eb5e8bc9e8f7c009cfd7f0bddad73 100 Pfam PF12840 Helix-turn-helix domain 13 69 5.0E-11 T 31-10-2018 N186_06020 396eb5e8bc9e8f7c009cfd7f0bddad73 100 SUPERFAMILY SSF46785 7 85 2.88E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_06020 396eb5e8bc9e8f7c009cfd7f0bddad73 100 SMART SM00418 10 88 9.4E-4 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_00350 c08ec28ebd9b7063df187c6906245979 518 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 419 1.1E-14 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_00350 c08ec28ebd9b7063df187c6906245979 518 PRINTS PR00131 Glycosyl hydrolase family 1 signature 468 480 1.1E-14 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_00350 c08ec28ebd9b7063df187c6906245979 518 PRINTS PR00131 Glycosyl hydrolase family 1 signature 444 461 1.1E-14 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_00350 c08ec28ebd9b7063df187c6906245979 518 PRINTS PR00131 Glycosyl hydrolase family 1 signature 334 348 1.1E-14 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_00350 c08ec28ebd9b7063df187c6906245979 518 SUPERFAMILY SSF51445 5 501 1.41E-122 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily N186_00350 c08ec28ebd9b7063df187c6906245979 518 Pfam PF00232 Glycosyl hydrolase family 1 129 497 3.7E-48 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_00350 c08ec28ebd9b7063df187c6906245979 518 Pfam PF00232 Glycosyl hydrolase family 1 3 99 4.9E-9 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 N186_00350 c08ec28ebd9b7063df187c6906245979 518 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 31-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site N186_00350 c08ec28ebd9b7063df187c6906245979 518 Gene3D G3DSA:3.20.20.80 4 515 2.2E-134 T 31-10-2018 N186_02810 ca7de7ec42aebdc09a5b954276239b97 128 Pfam PF01201 Ribosomal protein S8e 5 127 1.3E-25 T 31-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 N186_02810 ca7de7ec42aebdc09a5b954276239b97 128 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 128 27.926 T 31-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02810 ca7de7ec42aebdc09a5b954276239b97 128 Gene3D G3DSA:2.40.10.310 62 128 3.3E-30 T 31-10-2018 N186_02810 ca7de7ec42aebdc09a5b954276239b97 128 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 128 1.1E-31 T 31-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_06255 214aa54975ab042cbac455636650d7d6 158 SUPERFAMILY SSF54862 41 89 4.59E-16 T 31-10-2018 N186_06255 214aa54975ab042cbac455636650d7d6 158 Pfam PF00037 4Fe-4S binding domain 62 83 1.1E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_06255 214aa54975ab042cbac455636650d7d6 158 Gene3D G3DSA:3.30.70.20 30 96 9.1E-12 T 31-10-2018 N186_06255 214aa54975ab042cbac455636650d7d6 158 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 69 80 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_03640 762d46ea258e666a3876ae528531d5a5 116 Pfam PF06023 CRISPR-associated exonuclease Csa1 22 110 2.5E-29 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 N186_05045 09b9b539b8abd7c352158e796fcf6742 406 Gene3D G3DSA:3.30.300.10 28 156 1.0E-154 T 31-10-2018 N186_05045 09b9b539b8abd7c352158e796fcf6742 406 Gene3D G3DSA:3.30.300.280 158 398 1.0E-154 T 31-10-2018 N186_05045 09b9b539b8abd7c352158e796fcf6742 406 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 22 406 4.0E-127 T 31-10-2018 N186_05045 09b9b539b8abd7c352158e796fcf6742 406 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 4 402 4.1E-166 T 31-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 N186_05045 09b9b539b8abd7c352158e796fcf6742 406 Gene3D G3DSA:3.30.300.340 19 289 1.0E-154 T 31-10-2018 N186_00315 d852e4dd3132a0685c6153c323e4d7ab 414 SMART SM00093 60 414 1.0E-46 T 31-10-2018 IPR023796 Serpin domain N186_00315 d852e4dd3132a0685c6153c323e4d7ab 414 Gene3D G3DSA:3.30.497.10 66 361 4.1E-83 T 31-10-2018 N186_00315 d852e4dd3132a0685c6153c323e4d7ab 414 Pfam PF00079 Serpin (serine protease inhibitor) 54 414 2.0E-75 T 31-10-2018 IPR023796 Serpin domain N186_00315 d852e4dd3132a0685c6153c323e4d7ab 414 Gene3D G3DSA:2.30.39.10 210 414 4.1E-83 T 31-10-2018 N186_00315 d852e4dd3132a0685c6153c323e4d7ab 414 SUPERFAMILY SSF56574 32 414 3.8E-78 T 31-10-2018 IPR036186 Serpin superfamily N186_01495 89412ba568e1048b3816a277fb84540c 121 SUPERFAMILY SSF46785 25 111 3.14E-22 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_01495 89412ba568e1048b3816a277fb84540c 121 Pfam PF03551 Transcriptional regulator PadR-like family 29 96 5.9E-15 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal N186_01495 89412ba568e1048b3816a277fb84540c 121 Gene3D G3DSA:1.10.10.10 5 117 1.1E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04315 6c06a63ef92968858014e386e431e960 173 SUPERFAMILY SSF53163 1 150 2.22E-22 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily N186_04315 6c06a63ef92968858014e386e431e960 173 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 148 2.8E-17 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 N186_04315 6c06a63ef92968858014e386e431e960 173 Gene3D G3DSA:3.40.50.1450 1 158 3.5E-25 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 Pfam PF01131 DNA topoisomerase 159 570 2.6E-110 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 SUPERFAMILY SSF56712 5 584 1.27E-146 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 SMART SM00493 4 132 3.4E-20 T 31-10-2018 IPR006171 TOPRIM domain N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 Gene3D G3DSA:2.70.20.10 226 480 5.1E-124 T 31-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 Gene3D G3DSA:1.10.460.10 169 581 5.1E-124 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 398 414 2.0E-17 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 106 119 2.0E-17 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 317 326 2.0E-17 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 496 510 2.0E-17 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 202 220 2.0E-17 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 Pfam PF01751 Toprim domain 6 144 6.4E-18 T 31-10-2018 IPR006171 TOPRIM domain N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 SMART SM00436 135 232 1.7E-34 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 Gene3D G3DSA:3.40.50.140 2 159 8.1E-44 T 31-10-2018 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 SMART SM00437 275 533 1.4E-70 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 N186_05815 e81c80a1e725f982fe6a5ab7e606fd46 633 Gene3D G3DSA:1.10.290.10 283 412 5.1E-124 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 N186_02050 76a21b111eda67b4de9c1b1cc461e79b 172 Gene3D G3DSA:1.10.520.30 3 155 1.3E-7 T 31-10-2018 IPR023101 AF1862-like domain superfamily N186_02050 76a21b111eda67b4de9c1b1cc461e79b 172 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 12 94 9.6E-8 T 31-10-2018 IPR010160 CRISPR-associated protein, Cmr5 N186_02050 76a21b111eda67b4de9c1b1cc461e79b 172 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 1 168 1.7E-15 T 31-10-2018 IPR010160 CRISPR-associated protein, Cmr5 N186_02050 76a21b111eda67b4de9c1b1cc461e79b 172 SUPERFAMILY SSF158568 1 94 1.44E-13 T 31-10-2018 IPR023101 AF1862-like domain superfamily N186_02570 f73ab52fcf9a567e5378555976ed10f4 151 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 4 149 37.342 T 31-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 N186_02570 f73ab52fcf9a567e5378555976ed10f4 151 SUPERFAMILY SSF55040 5 149 5.36E-49 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_02570 f73ab52fcf9a567e5378555976ed10f4 151 Pfam PF01967 MoaC family 9 147 7.8E-49 T 31-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_02570 f73ab52fcf9a567e5378555976ed10f4 151 Gene3D G3DSA:3.30.70.640 4 151 1.2E-59 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_02570 f73ab52fcf9a567e5378555976ed10f4 151 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 2 137 6.7E-55 T 31-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_04670 4eff3211f7f7442155f29e25c9dfc21d 446 SUPERFAMILY SSF52540 118 294 2.19E-12 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04670 4eff3211f7f7442155f29e25c9dfc21d 446 Gene3D G3DSA:3.40.50.300 113 319 1.8E-11 T 31-10-2018 N186_00155 9a37b23e2338cfc25a383ee9a15ee037 163 Gene3D G3DSA:1.10.1760.20 5 159 2.8E-47 T 31-10-2018 N186_00155 9a37b23e2338cfc25a383ee9a15ee037 163 Pfam PF07155 ECF-type riboflavin transporter, S component 9 151 4.2E-40 T 31-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 N186_08960 1d626e907fa7d11e9e109f02f49a3d2a 137 Gene3D G3DSA:1.20.120.580 4 133 1.1E-5 T 31-10-2018 IPR037038 Bsu32300-like superfamily N186_08960 1d626e907fa7d11e9e109f02f49a3d2a 137 Pfam PF01934 Protein of unknown function DUF86 21 119 3.0E-16 T 31-10-2018 IPR008201 Protein of unknown function DUF86 N186_05765 172df8c7bfcdf6ec004538ab3015c843 215 Gene3D G3DSA:1.10.10.460 171 215 3.5E-19 T 31-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 N186_05765 172df8c7bfcdf6ec004538ab3015c843 215 Hamap MF_00052_A Ribonuclease HII [rnhB]. 3 214 30.32 T 31-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 N186_05765 172df8c7bfcdf6ec004538ab3015c843 215 Gene3D G3DSA:3.30.420.10 1 170 3.0E-46 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 N186_05765 172df8c7bfcdf6ec004538ab3015c843 215 Pfam PF01351 Ribonuclease HII 5 207 9.6E-47 T 31-10-2018 IPR024567 Ribonuclease HII/HIII domain N186_05765 172df8c7bfcdf6ec004538ab3015c843 215 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 4 213 1.9E-61 T 31-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 N186_05765 172df8c7bfcdf6ec004538ab3015c843 215 SUPERFAMILY SSF53098 3 214 1.0E-49 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily N186_00700 c661f6142c799b0289be8982daece9e2 383 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 109 128 - T 31-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 N186_00700 c661f6142c799b0289be8982daece9e2 383 Gene3D G3DSA:3.40.50.1100 91 368 6.6E-72 T 31-10-2018 N186_00700 c661f6142c799b0289be8982daece9e2 383 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 88 361 5.3E-42 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme N186_00700 c661f6142c799b0289be8982daece9e2 383 Gene3D G3DSA:3.40.50.1100 123 221 6.6E-72 T 31-10-2018 N186_00700 c661f6142c799b0289be8982daece9e2 383 SUPERFAMILY SSF53686 81 375 2.1E-59 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme N186_03645 b59d37775de17589f8e7a0495ba35e18 216 SUPERFAMILY SSF46785 147 208 9.37E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_03645 b59d37775de17589f8e7a0495ba35e18 216 Pfam PF01022 Bacterial regulatory protein, arsR family 150 193 3.7E-7 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_03645 b59d37775de17589f8e7a0495ba35e18 216 Gene3D G3DSA:1.10.10.10 147 206 5.3E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_03645 b59d37775de17589f8e7a0495ba35e18 216 Gene3D G3DSA:3.40.50.11700 2 146 2.0E-52 T 31-10-2018 N186_03645 b59d37775de17589f8e7a0495ba35e18 216 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 9 201 1.0E-27 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 N186_05460 a5c8d6f68cc72250fa5a05effb3db306 530 Gene3D G3DSA:1.10.287.950 177 310 8.4E-6 T 31-10-2018 N186_05460 a5c8d6f68cc72250fa5a05effb3db306 530 SUPERFAMILY SSF58104 45 255 6.67E-8 T 31-10-2018 N186_05460 a5c8d6f68cc72250fa5a05effb3db306 530 Gene3D G3DSA:1.20.5.340 436 523 1.6E-5 T 31-10-2018 N186_05460 a5c8d6f68cc72250fa5a05effb3db306 530 Gene3D G3DSA:1.20.120.20 8 174 3.8E-5 T 31-10-2018 N186_01320 246ea6461f838b3a39613b9a40ad08b4 397 SUPERFAMILY SSF53383 24 396 2.82E-113 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase N186_01320 246ea6461f838b3a39613b9a40ad08b4 397 Gene3D G3DSA:3.90.1150.10 30 392 1.7E-126 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 N186_01320 246ea6461f838b3a39613b9a40ad08b4 397 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 N186_01320 246ea6461f838b3a39613b9a40ad08b4 397 Gene3D G3DSA:3.40.640.10 55 292 1.7E-126 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 N186_01320 246ea6461f838b3a39613b9a40ad08b4 397 Pfam PF00155 Aminotransferase class I and II 36 391 9.0E-74 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 N186_00665 9f0627701719374b12e4ecbb8790e6f0 234 Gene3D G3DSA:3.40.1350.60 80 228 1.5E-33 T 31-10-2018 N186_00665 9f0627701719374b12e4ecbb8790e6f0 234 Gene3D G3DSA:2.40.50.580 1 79 1.3E-26 T 31-10-2018 N186_00665 9f0627701719374b12e4ecbb8790e6f0 234 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 3 228 6.2E-54 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein N186_00665 9f0627701719374b12e4ecbb8790e6f0 234 Pfam PF03749 Sugar fermentation stimulation protein 17 216 6.1E-47 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein N186_02030 706e0d3c9fc65730f6c96265c76b7775 339 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 158 246 5.7E-5 T 31-10-2018 IPR019117 CRISPR-associated protein, Cmr3 N186_07760 ff69f0a844c0ccd6399dac1598814b4d 115 Pfam PF01909 Nucleotidyltransferase domain 37 88 1.4E-8 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_07760 ff69f0a844c0ccd6399dac1598814b4d 115 SUPERFAMILY SSF81301 23 106 5.14E-14 T 31-10-2018 N186_07760 ff69f0a844c0ccd6399dac1598814b4d 115 Gene3D G3DSA:3.30.460.10 1 112 5.9E-19 T 31-10-2018 N186_01485 7c0514ef42261d0f1c0a2df698fd3863 254 Pfam PF00483 Nucleotidyl transferase 9 238 2.3E-27 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 N186_01485 7c0514ef42261d0f1c0a2df698fd3863 254 Gene3D G3DSA:3.90.550.10 1 248 4.8E-51 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_01485 7c0514ef42261d0f1c0a2df698fd3863 254 SUPERFAMILY SSF53448 4 238 3.13E-50 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_00415 32d988bab14c4122c1e32fffbb59b737 103 Gene3D G3DSA:3.40.50.1010 1 74 2.9E-13 T 31-10-2018 N186_00415 32d988bab14c4122c1e32fffbb59b737 103 SUPERFAMILY SSF88723 4 70 2.5E-8 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_07395 61ba4162d763e86107cdc95c66143b26 465 SUPERFAMILY SSF55103 238 464 5.07E-32 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 N186_07395 61ba4162d763e86107cdc95c66143b26 465 Gene3D G3DSA:3.40.462.40 272 419 2.6E-29 T 31-10-2018 N186_07395 61ba4162d763e86107cdc95c66143b26 465 Pfam PF02913 FAD linked oxidases, C-terminal domain 237 462 6.3E-33 T 31-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 N186_07395 61ba4162d763e86107cdc95c66143b26 465 Pfam PF01565 FAD binding domain 54 189 6.1E-38 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 N186_07395 61ba4162d763e86107cdc95c66143b26 465 SUPERFAMILY SSF56176 8 230 4.67E-55 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 N186_07395 61ba4162d763e86107cdc95c66143b26 465 Gene3D G3DSA:3.30.465.40 20 241 9.7E-65 T 31-10-2018 N186_08915 d0fd7664a574c585ee3df59972de5595 253 Gene3D G3DSA:3.40.50.300 12 243 2.8E-45 T 31-10-2018 N186_08915 d0fd7664a574c585ee3df59972de5595 253 Pfam PF00005 ABC transporter 29 172 9.7E-18 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_08915 d0fd7664a574c585ee3df59972de5595 253 SUPERFAMILY SSF52540 12 238 9.41E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01075 f0be453ad6601871711da87a739991ba 276 SUPERFAMILY SSF144020 22 274 2.35E-47 T 31-10-2018 IPR024064 FdhE-like superfamily N186_01075 f0be453ad6601871711da87a739991ba 276 Gene3D G3DSA:3.90.1670.10 8 276 1.1E-29 T 31-10-2018 IPR024064 FdhE-like superfamily N186_01075 f0be453ad6601871711da87a739991ba 276 Pfam PF04216 Protein involved in formate dehydrogenase formation 29 271 1.0E-15 T 31-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 N186_03320 934dcb301dfd9ba16218c6d895d69e9c 276 Gene3D G3DSA:3.10.330.20 25 85 1.1E-16 T 31-10-2018 N186_03320 934dcb301dfd9ba16218c6d895d69e9c 276 Gene3D G3DSA:3.40.50.150 88 276 1.3E-65 T 31-10-2018 N186_03320 934dcb301dfd9ba16218c6d895d69e9c 276 SUPERFAMILY SSF53335 25 275 6.94E-68 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_03320 934dcb301dfd9ba16218c6d895d69e9c 276 PIRSF PIRSF017269 20 276 2.3E-80 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 N186_03320 934dcb301dfd9ba16218c6d895d69e9c 276 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 95 252 2.3E-34 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 N186_06890 0612909f402a2176d1f0d215a325cf39 332 Pfam PF13732 Domain of unknown function (DUF4162) 232 326 3.6E-7 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 N186_06890 0612909f402a2176d1f0d215a325cf39 332 Pfam PF00005 ABC transporter 32 176 6.1E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_06890 0612909f402a2176d1f0d215a325cf39 332 SUPERFAMILY SSF52540 23 241 1.25E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06890 0612909f402a2176d1f0d215a325cf39 332 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_06890 0612909f402a2176d1f0d215a325cf39 332 Gene3D G3DSA:3.40.50.300 2 263 1.5E-62 T 31-10-2018 N186_06890 0612909f402a2176d1f0d215a325cf39 332 SMART SM00382 41 234 1.3E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_03455 04acd54c965a851520f5ac24016160ee 111 Pfam PF04242 Protein of unknown function (DUF424) 17 81 1.4E-9 T 31-10-2018 IPR007355 Protein of unknown function DUF424 N186_03455 04acd54c965a851520f5ac24016160ee 111 Gene3D G3DSA:3.30.1860.10 7 108 1.1E-17 T 31-10-2018 N186_06305 137f3828a5f4916f2d958bead309809d 425 Pfam PF04895 Archaeal Nre, C-terminal 325 423 3.2E-32 T 31-10-2018 IPR006979 Archaeal Nre, C-terminal N186_06305 137f3828a5f4916f2d958bead309809d 425 Pfam PF04894 Archaeal Nre, N-terminal 38 303 3.7E-92 T 31-10-2018 IPR006978 Archaeal Nre, N-terminal N186_06305 137f3828a5f4916f2d958bead309809d 425 Hamap MF_02096 DNA repair protein. 1 423 36.99 T 31-10-2018 IPR033167 Archaeal Nre GO:0006281 N186_09110 78deae3a5159a3338532590eaccaafcb 241 SUPERFAMILY SSF53474 2 241 2.81E-57 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_09110 78deae3a5159a3338532590eaccaafcb 241 Pfam PF05448 Acetyl xylan esterase (AXE1) 79 218 1.9E-12 T 31-10-2018 IPR008391 Acetyl xylan esterase N186_09110 78deae3a5159a3338532590eaccaafcb 241 Gene3D G3DSA:3.40.50.1820 2 241 6.4E-54 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_03700 e0fedc421d03d1b36d4cf6d4fee5418f 851 Pfam PF00271 Helicase conserved C-terminal domain 518 625 2.4E-14 T 31-10-2018 IPR001650 Helicase, C-terminal N186_03700 e0fedc421d03d1b36d4cf6d4fee5418f 851 SUPERFAMILY SSF52540 190 637 2.03E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03700 e0fedc421d03d1b36d4cf6d4fee5418f 851 SMART SM00487 164 493 2.1E-11 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain N186_03700 e0fedc421d03d1b36d4cf6d4fee5418f 851 Gene3D G3DSA:3.40.50.300 503 693 9.0E-23 T 31-10-2018 N186_03700 e0fedc421d03d1b36d4cf6d4fee5418f 851 Pfam PF00270 DEAD/DEAH box helicase 171 253 1.1E-9 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 N186_03700 e0fedc421d03d1b36d4cf6d4fee5418f 851 SMART SM00490 549 626 2.9E-10 T 31-10-2018 IPR001650 Helicase, C-terminal N186_03700 e0fedc421d03d1b36d4cf6d4fee5418f 851 SUPERFAMILY SSF52540 74 253 7.75E-13 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01375 63814c9ac8b8805424dff3d4f03cfc44 470 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 5 412 7.2E-50 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 N186_01375 63814c9ac8b8805424dff3d4f03cfc44 470 SUPERFAMILY SSF50475 5 302 1.1E-37 T 31-10-2018 N186_01375 63814c9ac8b8805424dff3d4f03cfc44 470 SUPERFAMILY SSF143968 317 413 1.24E-6 T 31-10-2018 N186_02930 d3a8a75faf63bb5aebd1f466a2caf665 184 SUPERFAMILY SSF53271 6 157 6.16E-34 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_02930 d3a8a75faf63bb5aebd1f466a2caf665 184 Pfam PF00156 Phosphoribosyl transferase domain 20 148 7.5E-23 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 N186_02930 d3a8a75faf63bb5aebd1f466a2caf665 184 Gene3D G3DSA:3.40.50.2020 4 169 6.5E-45 T 31-10-2018 N186_09615 357272f225d50b37600842f38888a206 258 Gene3D G3DSA:3.40.50.300 1 255 5.4E-60 T 31-10-2018 N186_09615 357272f225d50b37600842f38888a206 258 Pfam PF00005 ABC transporter 20 183 8.8E-24 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_09615 357272f225d50b37600842f38888a206 258 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 254 1.7E-10 T 31-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal N186_09615 357272f225d50b37600842f38888a206 258 SUPERFAMILY SSF52540 4 254 4.83E-54 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06280 0d8e86c81b2e0ab54a833e4b6c28ba03 1040 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 305 321 1.4E-9 T 31-10-2018 N186_06280 0d8e86c81b2e0ab54a833e4b6c28ba03 1040 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 539 551 1.4E-9 T 31-10-2018 N186_06280 0d8e86c81b2e0ab54a833e4b6c28ba03 1040 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 328 342 1.4E-9 T 31-10-2018 N186_06280 0d8e86c81b2e0ab54a833e4b6c28ba03 1040 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 542 548 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 N186_06280 0d8e86c81b2e0ab54a833e4b6c28ba03 1040 Pfam PF02384 N-6 DNA Methylase 284 379 1.1E-10 T 31-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 N186_06280 0d8e86c81b2e0ab54a833e4b6c28ba03 1040 SUPERFAMILY SSF53335 265 683 1.92E-32 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_06580 5d08c846e6dfc82fe23cbc92ca90fc6e 488 Pfam PF00361 Proton-conducting membrane transporter 47 314 2.1E-76 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06580 5d08c846e6dfc82fe23cbc92ca90fc6e 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 70 91 7.4E-42 T 31-10-2018 N186_06580 5d08c846e6dfc82fe23cbc92ca90fc6e 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 23 43 7.4E-42 T 31-10-2018 N186_06580 5d08c846e6dfc82fe23cbc92ca90fc6e 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 182 7.4E-42 T 31-10-2018 N186_06580 5d08c846e6dfc82fe23cbc92ca90fc6e 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 327 346 7.4E-42 T 31-10-2018 N186_06580 5d08c846e6dfc82fe23cbc92ca90fc6e 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 236 7.4E-42 T 31-10-2018 N186_06580 5d08c846e6dfc82fe23cbc92ca90fc6e 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 134 155 7.4E-42 T 31-10-2018 N186_06580 5d08c846e6dfc82fe23cbc92ca90fc6e 488 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 1 33 1.1E-8 T 31-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_04725 35731243a20bf8a7c9b50d3772ca1d33 797 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 23 776 46.634 T 31-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 N186_04725 35731243a20bf8a7c9b50d3772ca1d33 797 Pfam PF13718 GNAT acetyltransferase 2 470 587 1.7E-26 T 31-10-2018 IPR000182 GNAT domain N186_04725 35731243a20bf8a7c9b50d3772ca1d33 797 Gene3D G3DSA:3.40.630.30 431 634 1.0E-51 T 31-10-2018 N186_04725 35731243a20bf8a7c9b50d3772ca1d33 797 SUPERFAMILY SSF55729 505 636 7.27E-9 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase N186_04725 35731243a20bf8a7c9b50d3772ca1d33 797 Pfam PF05127 Helicase 250 430 8.1E-57 T 31-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 N186_04725 35731243a20bf8a7c9b50d3772ca1d33 797 Pfam PF08351 Domain of unknown function (DUF1726) 91 184 1.1E-26 T 31-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 N186_04725 35731243a20bf8a7c9b50d3772ca1d33 797 SUPERFAMILY SSF52540 46 373 1.04E-8 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04725 35731243a20bf8a7c9b50d3772ca1d33 797 Gene3D G3DSA:3.40.50.12320 246 420 2.8E-36 T 31-10-2018 N186_04725 35731243a20bf8a7c9b50d3772ca1d33 797 Gene3D G3DSA:3.40.50.11040 8 215 3.1E-10 T 31-10-2018 N186_09575 ad072e5ddef6d66d30c90fc995463acb 389 Pfam PF00149 Calcineurin-like phosphoesterase 2 206 9.8E-14 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 N186_09575 ad072e5ddef6d66d30c90fc995463acb 389 Gene3D G3DSA:3.60.21.10 1 253 1.2E-46 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_09575 ad072e5ddef6d66d30c90fc995463acb 389 SUPERFAMILY SSF56300 2 308 5.12E-50 T 31-10-2018 N186_05895 b9c335bffc245ebd14ce36cc2b357131 233 Gene3D G3DSA:1.10.150.20 146 218 2.6E-15 T 31-10-2018 N186_05895 b9c335bffc245ebd14ce36cc2b357131 233 SMART SM00891 5 85 6.6E-22 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 N186_05895 b9c335bffc245ebd14ce36cc2b357131 233 SUPERFAMILY SSF52980 3 133 2.41E-27 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_05895 b9c335bffc245ebd14ce36cc2b357131 233 Pfam PF14520 Helix-hairpin-helix domain 163 213 9.4E-9 T 31-10-2018 N186_05895 b9c335bffc245ebd14ce36cc2b357131 233 Pfam PF02732 ERCC4 domain 8 127 9.3E-15 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 N186_05895 b9c335bffc245ebd14ce36cc2b357131 233 SMART SM00278 193 212 0.54 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 N186_05895 b9c335bffc245ebd14ce36cc2b357131 233 SMART SM00278 161 180 17.0 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 N186_05895 b9c335bffc245ebd14ce36cc2b357131 233 Gene3D G3DSA:3.40.50.10130 1 133 5.4E-33 T 31-10-2018 N186_05895 b9c335bffc245ebd14ce36cc2b357131 233 SUPERFAMILY SSF47781 153 215 3.02E-10 T 31-10-2018 IPR010994 RuvA domain 2-like N186_03575 52251dc984e9ab765901a9daffc91ce9 282 SUPERFAMILY SSF111331 5 261 8.11E-43 T 31-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily N186_03575 52251dc984e9ab765901a9daffc91ce9 282 Hamap MF_00361 NAD kinase [nadK]. 4 275 19.65 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 N186_03575 52251dc984e9ab765901a9daffc91ce9 282 Gene3D G3DSA:3.40.50.10330 22 260 2.4E-41 T 31-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 N186_03575 52251dc984e9ab765901a9daffc91ce9 282 Gene3D G3DSA:2.60.200.30 122 250 2.4E-41 T 31-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 N186_03575 52251dc984e9ab765901a9daffc91ce9 282 Pfam PF01513 ATP-NAD kinase 49 254 2.8E-23 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 N186_08650 7e552296eb08164c18653d3f64928bac 559 Pfam PF05872 Bacterial protein of unknown function (DUF853) 396 491 1.8E-5 T 31-10-2018 IPR033186 Helicase HerA-like C-terminal N186_08650 7e552296eb08164c18653d3f64928bac 559 Gene3D G3DSA:3.40.50.300 322 514 3.9E-46 T 31-10-2018 N186_08650 7e552296eb08164c18653d3f64928bac 559 Gene3D G3DSA:3.40.50.300 111 301 9.1E-21 T 31-10-2018 N186_08650 7e552296eb08164c18653d3f64928bac 559 Pfam PF01935 Domain of unknown function DUF87 123 323 1.0E-39 T 31-10-2018 IPR002789 Helicase HerA, central domain N186_08650 7e552296eb08164c18653d3f64928bac 559 SUPERFAMILY SSF52540 114 506 2.33E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07585 d756e4f76476c4a41d89bbf2bbcd8046 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 290 6.0E-25 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_07585 d756e4f76476c4a41d89bbf2bbcd8046 293 SUPERFAMILY SSF161098 84 271 7.59E-25 T 31-10-2018 IPR035906 MetI-like superfamily N186_07585 d756e4f76476c4a41d89bbf2bbcd8046 293 Gene3D G3DSA:1.10.3720.10 80 284 3.6E-19 T 31-10-2018 IPR035906 MetI-like superfamily N186_09695 64890e34b7ed0fcb0347e4c656db44d1 390 Gene3D G3DSA:3.40.47.10 10 390 4.4E-117 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_09695 64890e34b7ed0fcb0347e4c656db44d1 390 Pfam PF00108 Thiolase, N-terminal domain 12 230 7.9E-21 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 N186_09695 64890e34b7ed0fcb0347e4c656db44d1 390 PIRSF PIRSF000429 4 390 8.4E-56 T 31-10-2018 IPR002155 Thiolase GO:0016747 N186_09695 64890e34b7ed0fcb0347e4c656db44d1 390 SUPERFAMILY SSF53901 18 362 6.23E-42 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 N186_09695 64890e34b7ed0fcb0347e4c656db44d1 390 Pfam PF02803 Thiolase, C-terminal domain 265 363 2.1E-10 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 N186_04035 52647646b1f74c4490fb5f37aff41e23 180 Gene3D G3DSA:1.20.5.340 35 158 2.3E-13 T 31-10-2018 N186_04035 52647646b1f74c4490fb5f37aff41e23 180 SUPERFAMILY SSF57997 67 150 1.05E-7 T 31-10-2018 N186_00690 5be0f8d6d7e105fabd60946375072c8d 180 Gene3D G3DSA:1.10.3210.10 7 176 8.8E-29 T 31-10-2018 N186_00690 5be0f8d6d7e105fabd60946375072c8d 180 SUPERFAMILY SSF109604 10 152 4.4E-24 T 31-10-2018 N186_00690 5be0f8d6d7e105fabd60946375072c8d 180 Pfam PF13023 HD domain 21 143 5.8E-16 T 31-10-2018 IPR006674 HD domain N186_00690 5be0f8d6d7e105fabd60946375072c8d 180 SMART SM00471 34 146 7.4E-9 T 31-10-2018 IPR003607 HD/PDEase domain N186_04925 699923964fc5c61814f6c7a9edb174da 295 SUPERFAMILY SSF52540 6 233 7.78E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04925 699923964fc5c61814f6c7a9edb174da 295 Gene3D G3DSA:3.40.50.300 4 280 2.0E-65 T 31-10-2018 N186_04925 699923964fc5c61814f6c7a9edb174da 295 Pfam PF00005 ABC transporter 23 174 1.7E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_04925 699923964fc5c61814f6c7a9edb174da 295 SMART SM00382 32 247 1.4E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04925 699923964fc5c61814f6c7a9edb174da 295 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_03565 ee5ac66df1e5e36b8a1e7801ff95d18b 192 SUPERFAMILY SSF50249 65 181 2.82E-17 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_03565 ee5ac66df1e5e36b8a1e7801ff95d18b 192 Gene3D G3DSA:2.20.70.10 153 186 3.5E-5 T 31-10-2018 N186_03565 ee5ac66df1e5e36b8a1e7801ff95d18b 192 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 9 191 23.776 T 31-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 N186_03565 ee5ac66df1e5e36b8a1e7801ff95d18b 192 SUPERFAMILY SSF110324 9 60 1.23E-5 T 31-10-2018 N186_03565 ee5ac66df1e5e36b8a1e7801ff95d18b 192 Gene3D G3DSA:2.40.50.140 64 152 6.8E-16 T 31-10-2018 N186_03565 ee5ac66df1e5e36b8a1e7801ff95d18b 192 Gene3D G3DSA:2.40.50.100 7 61 4.3E-7 T 31-10-2018 N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 SUPERFAMILY SSF53218 179 324 4.71E-36 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 SUPERFAMILY SSF53850 425 586 3.86E-9 T 31-10-2018 N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 168 1.2E-35 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 254 288 - T 31-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 Pfam PF00994 Probable molybdopterin binding domain 181 317 2.1E-23 T 31-10-2018 IPR001453 MoaB/Mog domain N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 Pfam PF12727 PBP superfamily domain 431 614 3.1E-48 T 31-10-2018 IPR024370 PBP domain N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 Gene3D G3DSA:2.40.340.10 329 401 3.6E-15 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 SUPERFAMILY SSF63867 329 400 1.96E-14 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 Pfam PF03454 MoeA C-terminal region (domain IV) 332 400 1.3E-13 T 31-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 SMART SM00852 181 319 3.4E-32 T 31-10-2018 IPR001453 MoaB/Mog domain N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 SUPERFAMILY SSF63882 1 176 9.94E-47 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 Gene3D G3DSA:3.40.980.10 176 317 5.7E-91 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 Gene3D G3DSA:3.90.105.10 24 175 5.7E-91 T 31-10-2018 N186_05200 8af64e2a8615be0e5a200cf465b56c24 640 Gene3D G3DSA:2.170.190.11 46 142 5.7E-91 T 31-10-2018 N186_03940 93c07708abda12da30c386dae1e5bb5d 529 Pfam PF00437 Type II/IV secretion system protein 186 373 1.9E-10 T 31-10-2018 IPR001482 Type II/IV secretion system protein N186_03940 93c07708abda12da30c386dae1e5bb5d 529 Gene3D G3DSA:3.40.50.300 243 434 8.2E-22 T 31-10-2018 N186_03940 93c07708abda12da30c386dae1e5bb5d 529 Gene3D G3DSA:3.40.50.1010 3 129 3.0E-13 T 31-10-2018 N186_03940 93c07708abda12da30c386dae1e5bb5d 529 SMART SM00382 261 396 0.0021 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_03940 93c07708abda12da30c386dae1e5bb5d 529 SUPERFAMILY SSF88723 5 128 2.55E-5 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_03940 93c07708abda12da30c386dae1e5bb5d 529 SUPERFAMILY SSF52540 143 429 8.11E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04580 4bda78326d5af06ce32dab49526c748d 235 Pfam PF01909 Nucleotidyltransferase domain 44 67 1.8E-5 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_04580 4bda78326d5af06ce32dab49526c748d 235 SUPERFAMILY SSF81301 12 69 2.47E-7 T 31-10-2018 N186_04580 4bda78326d5af06ce32dab49526c748d 235 PIRSF PIRSF005928 7 234 4.8E-62 T 31-10-2018 IPR009185 Predicted nucleotidyltransferase N186_00335 e00d423bdc1bfd268de3e76d77489a2c 277 Gene3D G3DSA:1.10.3720.10 52 269 9.8E-12 T 31-10-2018 IPR035906 MetI-like superfamily N186_00335 e00d423bdc1bfd268de3e76d77489a2c 277 SUPERFAMILY SSF161098 58 256 3.79E-13 T 31-10-2018 IPR035906 MetI-like superfamily N186_00335 e00d423bdc1bfd268de3e76d77489a2c 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 275 5.0E-21 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_01545 3ec06e8e22eb9bb2096388ef7444066e 140 Gene3D G3DSA:3.30.1960.10 1 136 1.5E-34 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 N186_01545 3ec06e8e22eb9bb2096388ef7444066e 140 SUPERFAMILY SSF111278 8 135 2.62E-29 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 N186_01545 3ec06e8e22eb9bb2096388ef7444066e 140 Pfam PF02676 Methyltransferase TYW3 37 135 7.9E-22 T 31-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 144 155 2.2E-21 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 2.2E-21 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 280 303 2.2E-21 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 60 79 2.2E-21 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 Gene3D G3DSA:3.40.50.1370 144 302 1.6E-103 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 60 67 - T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 SUPERFAMILY SSF53671 12 316 7.33E-94 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 313 5.6E-23 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 Gene3D G3DSA:3.40.50.1370 19 312 1.6E-103 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 17 156 2.8E-45 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 296 310 2.5E-34 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 274 279 2.5E-34 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 143 160 2.5E-34 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 235 244 2.5E-34 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 50 72 2.5E-34 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 89 98 2.5E-34 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 16 317 36.024 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_06985 43599d14f9fe13c0c99345b7617a6a7f 317 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 17 315 4.6E-111 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_01870 8795e158f7d9ca8ed0b97f24146446ec 361 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 318 6.9E-13 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD N186_01870 8795e158f7d9ca8ed0b97f24146446ec 361 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 316 4.8E-39 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD N186_09355 290b5425eb844ffef906505fa7db14cd 501 Gene3D G3DSA:3.90.550.10 71 280 5.8E-48 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_09355 290b5425eb844ffef906505fa7db14cd 501 SUPERFAMILY SSF53448 74 339 2.25E-38 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_09355 290b5425eb844ffef906505fa7db14cd 501 Pfam PF13641 Glycosyltransferase like family 2 74 297 7.5E-24 T 31-10-2018 N186_06640 b3572ca388d1ac441f8dc7236020b17b 457 Pfam PF00361 Proton-conducting membrane transporter 115 406 4.9E-38 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06640 b3572ca388d1ac441f8dc7236020b17b 457 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 364 390 1.5E-5 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06640 b3572ca388d1ac441f8dc7236020b17b 457 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 149 173 1.5E-5 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06640 b3572ca388d1ac441f8dc7236020b17b 457 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 311 330 1.5E-5 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_03745 bf61ab40cda822e2156d9410390ed9c8 347 Pfam PF05167 Uncharacterised ACR (DUF711) 172 326 1.1E-29 T 31-10-2018 IPR007841 Uncharacterised protein family UPF0210 N186_03745 bf61ab40cda822e2156d9410390ed9c8 347 Gene3D G3DSA:3.20.70.20 4 346 9.3E-52 T 31-10-2018 N186_03745 bf61ab40cda822e2156d9410390ed9c8 347 SUPERFAMILY SSF51998 4 344 1.1E-63 T 31-10-2018 N186_05750 6d559bb792a4b7616da1b717ef99e04f 312 SUPERFAMILY SSF56235 25 303 3.86E-81 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_05750 6d559bb792a4b7616da1b717ef99e04f 312 Pfam PF01112 Asparaginase 7 301 7.5E-90 T 31-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 N186_05750 6d559bb792a4b7616da1b717ef99e04f 312 Gene3D G3DSA:3.60.20.30 179 308 1.2E-41 T 31-10-2018 N186_01105 5d1dca462281b604603c76dbb77b5a21 177 SUPERFAMILY SSF102405 12 166 3.66E-19 T 31-10-2018 N186_01105 5d1dca462281b604603c76dbb77b5a21 177 Gene3D G3DSA:3.40.50.450 1 169 4.3E-20 T 31-10-2018 N186_08940 7c865bb0123af5901f94a8c8076a939e 465 Pfam PF01554 MatE 30 189 2.3E-16 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 N186_08940 7c865bb0123af5901f94a8c8076a939e 465 Pfam PF01554 MatE 253 414 3.1E-21 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 N186_08940 7c865bb0123af5901f94a8c8076a939e 465 PIRSF PIRSF006603 3 462 7.1E-85 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 N186_00895 f62b0c51b024cf3af17e6959e37b6ead 284 Pfam PF06177 QueT transporter 98 259 9.8E-11 T 31-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 N186_00895 f62b0c51b024cf3af17e6959e37b6ead 284 Gene3D G3DSA:1.10.1760.20 91 273 2.6E-5 T 31-10-2018 N186_01055 36f86f264ba6cb43a492cdf4f92fd82e 370 SMART SM00729 92 300 1.1E-4 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_01055 36f86f264ba6cb43a492cdf4f92fd82e 370 PIRSF PIRSF004869 7 334 1.5E-100 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted N186_01055 36f86f264ba6cb43a492cdf4f92fd82e 370 Gene3D G3DSA:3.20.20.70 86 307 1.6E-35 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_01055 36f86f264ba6cb43a492cdf4f92fd82e 370 Pfam PF04055 Radical SAM superfamily 98 255 8.9E-23 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_01055 36f86f264ba6cb43a492cdf4f92fd82e 370 SUPERFAMILY SSF102114 70 335 3.27E-39 T 31-10-2018 N186_01055 36f86f264ba6cb43a492cdf4f92fd82e 370 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 23 362 1.1E-102 T 31-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme N186_04060 3ef0320b2ecf48171db3fa38b432f192 348 Gene3D G3DSA:1.10.3470.10 10 344 3.4E-79 T 31-10-2018 IPR037294 ABC transporter, BtuC-like N186_04060 3ef0320b2ecf48171db3fa38b432f192 348 SUPERFAMILY SSF81345 9 339 7.85E-63 T 31-10-2018 IPR037294 ABC transporter, BtuC-like N186_04060 3ef0320b2ecf48171db3fa38b432f192 348 Pfam PF01032 FecCD transport family 23 339 2.1E-76 T 31-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 N186_05075 bb23bee61297ed2db97e0364ee1484c8 167 Gene3D G3DSA:3.40.50.150 3 165 1.4E-20 T 31-10-2018 N186_05075 bb23bee61297ed2db97e0364ee1484c8 167 SUPERFAMILY SSF53335 10 133 1.75E-19 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_05075 bb23bee61297ed2db97e0364ee1484c8 167 Pfam PF08241 Methyltransferase domain 43 129 1.7E-11 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 N186_00750 3e3f10459663fed77dc91fa27266446c 443 SUPERFAMILY SSF103473 11 381 2.62E-10 T 31-10-2018 IPR036259 MFS transporter superfamily N186_01820 73ce65b19b14f6aed0545931041209ad 154 Pfam PF06146 Phosphate-starvation-inducible E 70 135 6.5E-10 T 31-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like N186_07400 80f22fd2962598257804dbff230e5d2c 213 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 19 30 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_04995 de7aec78e240192a6eddc955a5d198df 384 Gene3D G3DSA:3.40.50.300 154 332 3.7E-25 T 31-10-2018 N186_04995 de7aec78e240192a6eddc955a5d198df 384 Pfam PF00437 Type II/IV secretion system protein 168 286 1.3E-16 T 31-10-2018 IPR001482 Type II/IV secretion system protein N186_04995 de7aec78e240192a6eddc955a5d198df 384 SUPERFAMILY SSF52540 163 315 6.46E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05545 27a64e47a4d233b36f09a6888395f658 127 Gene3D G3DSA:2.20.25.10 54 110 2.6E-11 T 31-10-2018 N186_05545 27a64e47a4d233b36f09a6888395f658 127 SUPERFAMILY SSF158997 56 100 1.44E-12 T 31-10-2018 N186_05545 27a64e47a4d233b36f09a6888395f658 127 Pfam PF03966 Trm112p-like protein 1 85 7.3E-15 T 31-10-2018 IPR005651 Trm112-like N186_00330 efffb76b684b5d3cf52fe4c6a09f8bde 326 SUPERFAMILY SSF52540 5 262 3.63E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00330 efffb76b684b5d3cf52fe4c6a09f8bde 326 SMART SM00382 34 239 3.7E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00330 efffb76b684b5d3cf52fe4c6a09f8bde 326 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_00330 efffb76b684b5d3cf52fe4c6a09f8bde 326 Pfam PF00005 ABC transporter 26 181 1.2E-22 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00330 efffb76b684b5d3cf52fe4c6a09f8bde 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 299 9.5E-19 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_00330 efffb76b684b5d3cf52fe4c6a09f8bde 326 Gene3D G3DSA:3.40.50.300 3 326 9.3E-79 T 31-10-2018 N186_00330 efffb76b684b5d3cf52fe4c6a09f8bde 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 319 2.1E-24 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_08800 7d82fff86d5b987fd4459f66b7e7a4d1 239 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 11 77 1.5E-22 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal N186_08800 7d82fff86d5b987fd4459f66b7e7a4d1 239 SUPERFAMILY SSF46785 4 92 1.44E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_08800 7d82fff86d5b987fd4459f66b7e7a4d1 239 Gene3D G3DSA:1.10.10.10 5 104 1.9E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_09045 aa23380164d0544b24171c5b2fbeb01a 254 Gene3D G3DSA:3.40.50.1580 3 254 3.0E-78 T 31-10-2018 N186_09045 aa23380164d0544b24171c5b2fbeb01a 254 SUPERFAMILY SSF53167 3 246 9.43E-70 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 N186_09045 aa23380164d0544b24171c5b2fbeb01a 254 Pfam PF01048 Phosphorylase superfamily 16 242 7.0E-34 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 N186_08405 60762dc2d9e7779ad068f18e91cffc9c 273 Gene3D G3DSA:3.40.630.30 3 150 7.8E-10 T 31-10-2018 N186_08405 60762dc2d9e7779ad068f18e91cffc9c 273 Pfam PF00583 Acetyltransferase (GNAT) family 41 123 1.7E-5 T 31-10-2018 IPR000182 GNAT domain N186_08405 60762dc2d9e7779ad068f18e91cffc9c 273 SUPERFAMILY SSF55729 1 152 2.52E-12 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase N186_06485 01719d5f7ac6061fbbcf4a5bb0856289 462 SUPERFAMILY SSF55326 41 126 3.66E-15 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily N186_06485 01719d5f7ac6061fbbcf4a5bb0856289 462 Gene3D G3DSA:3.30.1330.10 28 127 7.4E-15 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily N186_06485 01719d5f7ac6061fbbcf4a5bb0856289 462 Gene3D G3DSA:3.40.225.10 291 458 5.9E-30 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily N186_06485 01719d5f7ac6061fbbcf4a5bb0856289 462 Pfam PF02769 AIR synthase related protein, C-terminal domain 157 267 9.9E-9 T 31-10-2018 IPR010918 PurM-like, C-terminal domain N186_06485 01719d5f7ac6061fbbcf4a5bb0856289 462 SUPERFAMILY SSF53639 297 454 1.45E-28 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily N186_06485 01719d5f7ac6061fbbcf4a5bb0856289 462 Gene3D G3DSA:3.90.650.10 131 282 2.5E-15 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily N186_06485 01719d5f7ac6061fbbcf4a5bb0856289 462 SUPERFAMILY SSF56042 133 273 2.39E-16 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily N186_06485 01719d5f7ac6061fbbcf4a5bb0856289 462 Pfam PF00586 AIR synthase related protein, N-terminal domain 45 125 1.0E-9 T 31-10-2018 IPR016188 PurM-like, N-terminal domain N186_06485 01719d5f7ac6061fbbcf4a5bb0856289 462 Pfam PF10120 Thiamine-phosphate synthase 299 452 7.0E-29 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 N186_02800 8b5752686b362dc2ae57e060bb6ee420 548 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 7 518 40.349 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 N186_02800 8b5752686b362dc2ae57e060bb6ee420 548 Pfam PF01702 Queuine tRNA-ribosyltransferase 109 331 1.6E-44 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 N186_02800 8b5752686b362dc2ae57e060bb6ee420 548 SUPERFAMILY SSF51713 6 355 1.22E-103 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 N186_02800 8b5752686b362dc2ae57e060bb6ee420 548 Gene3D G3DSA:3.40.50.10630 369 529 7.3E-8 T 31-10-2018 N186_02800 8b5752686b362dc2ae57e060bb6ee420 548 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 7 339 4.5E-76 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 N186_02800 8b5752686b362dc2ae57e060bb6ee420 548 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 7 469 1.2E-140 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 N186_02800 8b5752686b362dc2ae57e060bb6ee420 548 SUPERFAMILY SSF52141 382 503 1.57E-12 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 N186_02800 8b5752686b362dc2ae57e060bb6ee420 548 Gene3D G3DSA:3.20.20.105 3 357 5.0E-104 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 N186_00410 d6b87cdafa622998c577284a29eddafc 259 Pfam PF02535 ZIP Zinc transporter 119 255 4.2E-19 T 31-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 N186_06800 6c6bcd365519e88960f64f7c598167ce 112 Pfam PF13247 4Fe-4S dicluster domain 5 76 7.1E-13 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_06800 6c6bcd365519e88960f64f7c598167ce 112 SUPERFAMILY SSF54862 2 109 2.43E-35 T 31-10-2018 N186_06800 6c6bcd365519e88960f64f7c598167ce 112 Gene3D G3DSA:3.30.70.20 1 111 2.1E-34 T 31-10-2018 N186_06800 6c6bcd365519e88960f64f7c598167ce 112 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 19 30 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_08695 c24e579fc77829b4dbb23a0fdd8e71ac 294 Gene3D G3DSA:1.10.10.10 191 278 1.1E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_08695 c24e579fc77829b4dbb23a0fdd8e71ac 294 SUPERFAMILY SSF46785 195 271 7.08E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_00880 ca4c914d5a1574ae22996ccacc637d68 266 Pfam PF00005 ABC transporter 19 163 1.8E-26 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_00880 ca4c914d5a1574ae22996ccacc637d68 266 SMART SM00382 27 212 3.3E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_00880 ca4c914d5a1574ae22996ccacc637d68 266 Gene3D G3DSA:3.40.50.300 1 265 1.8E-66 T 31-10-2018 N186_00880 ca4c914d5a1574ae22996ccacc637d68 266 SUPERFAMILY SSF52540 2 227 7.68E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06755 51afbd90961fd6985602f8ae74625d59 425 SUPERFAMILY SSF103473 3 404 9.68E-69 T 31-10-2018 IPR036259 MFS transporter superfamily N186_06755 51afbd90961fd6985602f8ae74625d59 425 Gene3D G3DSA:1.20.1250.20 1 195 1.2E-37 T 31-10-2018 N186_06755 51afbd90961fd6985602f8ae74625d59 425 Gene3D G3DSA:1.20.1250.20 211 407 4.8E-25 T 31-10-2018 N186_06755 51afbd90961fd6985602f8ae74625d59 425 Pfam PF07690 Major Facilitator Superfamily 14 304 1.9E-40 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_09540 2dbbc03512fd4ae1f79594b5cbadbecf 219 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 159 200 2.6E-10 T 31-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 N186_09540 2dbbc03512fd4ae1f79594b5cbadbecf 219 SUPERFAMILY SSF52833 5 218 2.12E-74 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_09540 2dbbc03512fd4ae1f79594b5cbadbecf 219 Gene3D G3DSA:3.40.30.10 8 148 6.0E-52 T 31-10-2018 N186_09540 2dbbc03512fd4ae1f79594b5cbadbecf 219 Gene3D G3DSA:3.30.1020.10 149 219 3.8E-31 T 31-10-2018 N186_09540 2dbbc03512fd4ae1f79594b5cbadbecf 219 Hamap MF_00401 Peroxiredoxin. 7 219 52.526 T 31-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 N186_09540 2dbbc03512fd4ae1f79594b5cbadbecf 219 PIRSF PIRSF000239 2 213 2.9E-81 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 N186_09540 2dbbc03512fd4ae1f79594b5cbadbecf 219 Pfam PF00578 AhpC/TSA family 10 138 1.3E-36 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 N186_06590 e8efebbcef2439e0c2e41b97bb59cccd 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 21 110 7.3E-10 T 31-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06590 e8efebbcef2439e0c2e41b97bb59cccd 121 Gene3D G3DSA:1.20.58.1610 1 117 3.1E-10 T 31-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_02110 e69c41cf3b44561e8d360f7f2ef4f5f1 165 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 42 165 27.626 T 31-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 N186_02110 e69c41cf3b44561e8d360f7f2ef4f5f1 165 SUPERFAMILY SSF52042 37 164 3.27E-40 T 31-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02110 e69c41cf3b44561e8d360f7f2ef4f5f1 165 SMART SM01393 58 164 2.0E-54 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02110 e69c41cf3b44561e8d360f7f2ef4f5f1 165 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 59 164 8.0E-31 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02110 e69c41cf3b44561e8d360f7f2ef4f5f1 165 Pfam PF01655 Ribosomal protein L32 59 164 3.5E-37 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_07115 600005b2d0d19dba287cd826cc8509ab 255 Pfam PF13649 Methyltransferase domain 42 135 2.6E-22 T 31-10-2018 N186_07115 600005b2d0d19dba287cd826cc8509ab 255 Gene3D G3DSA:2.20.25.110 144 213 4.1E-51 T 31-10-2018 N186_07115 600005b2d0d19dba287cd826cc8509ab 255 SUPERFAMILY SSF53335 6 253 2.11E-48 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_07115 600005b2d0d19dba287cd826cc8509ab 255 Gene3D G3DSA:3.40.50.150 7 252 4.1E-51 T 31-10-2018 N186_02000 bb9ea0c10897b4cfda3a473e95baf3de 334 Gene3D G3DSA:2.40.30.10 38 313 5.1E-117 T 31-10-2018 N186_02000 bb9ea0c10897b4cfda3a473e95baf3de 334 Gene3D G3DSA:3.30.1430.10 77 183 5.1E-117 T 31-10-2018 N186_02000 bb9ea0c10897b4cfda3a473e95baf3de 334 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 328 4.0E-125 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02000 bb9ea0c10897b4cfda3a473e95baf3de 334 Gene3D G3DSA:4.10.960.10 6 251 5.1E-117 T 31-10-2018 N186_02000 bb9ea0c10897b4cfda3a473e95baf3de 334 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 331 44.542 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02000 bb9ea0c10897b4cfda3a473e95baf3de 334 ProSitePatterns PS00474 Ribosomal protein L3 signature. 188 211 - T 31-10-2018 IPR019926 Ribosomal protein L3, conserved site N186_02000 bb9ea0c10897b4cfda3a473e95baf3de 334 Pfam PF00297 Ribosomal protein L3 5 314 7.8E-75 T 31-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_02000 bb9ea0c10897b4cfda3a473e95baf3de 334 SUPERFAMILY SSF50447 3 327 2.83E-81 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_02085 49d259743ec8856177e7f0b7e30254d5 157 Gene3D G3DSA:4.10.990.10 8 57 1.8E-10 T 31-10-2018 IPR027386 50S ribosomal protein L15, N-terminal N186_02085 49d259743ec8856177e7f0b7e30254d5 157 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 149 14.006 T 31-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 N186_02085 49d259743ec8856177e7f0b7e30254d5 157 Gene3D G3DSA:3.100.10.10 64 153 2.0E-19 T 31-10-2018 N186_02085 49d259743ec8856177e7f0b7e30254d5 157 SUPERFAMILY SSF52080 10 149 3.66E-31 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily N186_02085 49d259743ec8856177e7f0b7e30254d5 157 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 33 147 1.3E-18 T 31-10-2018 IPR021131 Ribosomal protein L18e/L15P N186_01450 45989529deb16762cfa0239b69322370 295 Gene3D G3DSA:1.10.443.10 107 294 3.1E-62 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 N186_01450 45989529deb16762cfa0239b69322370 295 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 15 285 46.127 T 31-10-2018 IPR033686 Tyrosine recombinase XerA N186_01450 45989529deb16762cfa0239b69322370 295 Pfam PF00589 Phage integrase family 114 273 1.8E-46 T 31-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 N186_01450 45989529deb16762cfa0239b69322370 295 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 19 94 1.0E-8 T 31-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 N186_01450 45989529deb16762cfa0239b69322370 295 SUPERFAMILY SSF56349 16 280 2.03E-65 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 N186_01450 45989529deb16762cfa0239b69322370 295 Gene3D G3DSA:1.10.150.130 11 102 1.3E-12 T 31-10-2018 IPR010998 Integrase/recombinase, N-terminal N186_08900 576efd21ac8d839170b19a4e16c492ab 288 Gene3D G3DSA:1.20.5.1070 32 107 7.9E-10 T 31-10-2018 N186_08900 576efd21ac8d839170b19a4e16c492ab 288 Gene3D G3DSA:3.90.20.10 108 189 2.5E-6 T 31-10-2018 N186_08900 576efd21ac8d839170b19a4e16c492ab 288 SUPERFAMILY SSF57997 31 181 3.66E-12 T 31-10-2018 N186_00515 69c9976c698b26f112785ae914daae12 116 Gene3D G3DSA:3.40.1230.10 1 116 6.2E-33 T 31-10-2018 IPR036748 MTH938-like superfamily N186_00515 69c9976c698b26f112785ae914daae12 116 SUPERFAMILY SSF64076 2 116 4.45E-23 T 31-10-2018 IPR036748 MTH938-like superfamily N186_00515 69c9976c698b26f112785ae914daae12 116 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 3 113 1.0E-22 T 31-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 150 165 3.2E-35 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 261 277 3.2E-35 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 205 222 3.2E-35 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 229 250 3.2E-35 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 132 149 3.2E-35 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 103 114 3.2E-35 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 Gene3D G3DSA:1.10.10.10 10 158 3.2E-48 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 SUPERFAMILY SSF56726 78 380 6.02E-91 T 31-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 Pfam PF04406 Type IIB DNA topoisomerase 79 155 5.4E-20 T 31-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 13 380 39.917 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 Gene3D G3DSA:3.40.1360.10 159 380 3.0E-80 T 31-10-2018 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 179 197 4.1E-38 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 351 374 4.1E-38 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 45 65 4.1E-38 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 235 255 4.1E-38 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 N186_04795 2abe568f5fd72a109a55972b1063e8f9 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 126 143 4.1E-38 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 N186_09585 3a4e15ef2e65bd1bfa9852562b5c5363 123 SUPERFAMILY SSF103196 7 121 1.7E-14 T 31-10-2018 N186_09585 3a4e15ef2e65bd1bfa9852562b5c5363 123 Gene3D G3DSA:3.30.450.30 8 123 4.4E-17 T 31-10-2018 N186_09585 3a4e15ef2e65bd1bfa9852562b5c5363 123 Pfam PF03259 Roadblock/LC7 domain 12 100 2.4E-10 T 31-10-2018 IPR004942 Roadblock/LAMTOR2 domain N186_09585 3a4e15ef2e65bd1bfa9852562b5c5363 123 SMART SM00960 10 100 5.6E-15 T 31-10-2018 IPR004942 Roadblock/LAMTOR2 domain N186_00165 80cfb20b49074df0564c649f5d97818d 87 Gene3D G3DSA:3.30.70.1340 3 87 1.9E-27 T 31-10-2018 IPR023129 MTH889-like domain superfamily N186_00165 80cfb20b49074df0564c649f5d97818d 87 Pfam PF02680 Uncharacterized ArCR, COG1888 8 85 7.2E-25 T 31-10-2018 IPR003831 Protein of unknown function DUF211 N186_00165 80cfb20b49074df0564c649f5d97818d 87 SUPERFAMILY SSF160363 7 86 3.01E-24 T 31-10-2018 IPR023129 MTH889-like domain superfamily N186_00165 80cfb20b49074df0564c649f5d97818d 87 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 13 86 8.0E-11 T 31-10-2018 IPR003831 Protein of unknown function DUF211 N186_04955 faade97c3b2da828eefe80d99917f358 152 Pfam PF01638 HxlR-like helix-turn-helix 57 131 8.6E-7 T 31-10-2018 IPR002577 Helix-turn-helix, HxlR type N186_04955 faade97c3b2da828eefe80d99917f358 152 Gene3D G3DSA:1.10.10.10 42 145 1.2E-13 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04955 faade97c3b2da828eefe80d99917f358 152 SUPERFAMILY SSF46785 46 141 1.81E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_02895 8ab7c796f86257b218fcbe3494ed8967 94 Gene3D G3DSA:2.40.10.230 1 76 7.5E-20 T 31-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain N186_02895 8ab7c796f86257b218fcbe3494ed8967 94 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 19 73 3.0E-4 T 31-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 N186_02895 8ab7c796f86257b218fcbe3494ed8967 94 SUPERFAMILY SSF50447 1 74 2.15E-13 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_02895 8ab7c796f86257b218fcbe3494ed8967 94 Pfam PF04410 Gar1/Naf1 RNA binding region 14 79 1.9E-7 T 31-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 N186_04340 0b25b7f70601b085635ec16feeb5d7a9 446 Gene3D G3DSA:1.10.1060.10 2 139 1.3E-8 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 N186_04340 0b25b7f70601b085635ec16feeb5d7a9 446 Pfam PF13534 4Fe-4S dicluster domain 32 115 1.1E-4 T 31-10-2018 N186_04340 0b25b7f70601b085635ec16feeb5d7a9 446 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_04340 0b25b7f70601b085635ec16feeb5d7a9 446 SUPERFAMILY SSF46548 27 130 1.17E-15 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 N186_04340 0b25b7f70601b085635ec16feeb5d7a9 446 Pfam PF02754 Cysteine-rich domain 307 356 0.0013 T 31-10-2018 IPR004017 Cysteine-rich domain N186_04340 0b25b7f70601b085635ec16feeb5d7a9 446 Pfam PF02754 Cysteine-rich domain 395 421 0.031 T 31-10-2018 IPR004017 Cysteine-rich domain N186_03805 b587c40dfe656fead58521d5f5888e1c 443 SUPERFAMILY SSF56731 168 303 4.71E-11 T 31-10-2018 N186_03805 b587c40dfe656fead58521d5f5888e1c 443 Hamap MF_00007 DNA primase DnaG [dnaG]. 8 404 31.961 T 31-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 N186_03805 b587c40dfe656fead58521d5f5888e1c 443 Pfam PF13662 Toprim domain 171 235 4.2E-9 T 31-10-2018 IPR006171 TOPRIM domain N186_03805 b587c40dfe656fead58521d5f5888e1c 443 Gene3D G3DSA:3.40.1360.10 165 260 1.9E-14 T 31-10-2018 N186_03805 b587c40dfe656fead58521d5f5888e1c 443 SMART SM00493 171 240 1.2E-14 T 31-10-2018 IPR006171 TOPRIM domain N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 ProSitePatterns PS00116 DNA polymerase family B signature. 434 442 - T 31-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 SUPERFAMILY SSF53098 8 186 2.28E-5 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 SMART SM00486 4 446 0.0043 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 Pfam PF00136 DNA polymerase family B 296 336 1.3E-6 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 Pfam PF00136 DNA polymerase family B 343 586 1.6E-19 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 SUPERFAMILY SSF56672 258 643 8.34E-70 T 31-10-2018 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 432 440 5.0E-6 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 380 392 5.0E-6 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 311 324 5.0E-6 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 Gene3D G3DSA:3.90.1600.10 301 478 1.5E-38 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 Gene3D G3DSA:1.10.287.690 344 401 1.5E-38 T 31-10-2018 N186_00060 add9b23c67d12df86b5f04ffcaad021d 653 Gene3D G3DSA:1.10.132.60 489 603 4.1E-14 T 31-10-2018 N186_00370 745736547781b6edf6a01d308073b1a5 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 226 6.1E-44 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 N186_00370 745736547781b6edf6a01d308073b1a5 331 Gene3D G3DSA:3.40.50.720 1 331 2.1E-94 T 31-10-2018 N186_00370 745736547781b6edf6a01d308073b1a5 331 SUPERFAMILY SSF51735 2 328 2.49E-82 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_08390 3aeae717ac9c05e2e9a81902439c5772 274 Pfam PF01882 Protein of unknown function DUF58 14 79 2.1E-9 T 31-10-2018 IPR002881 Domain of unknown function DUF58 N186_08390 3aeae717ac9c05e2e9a81902439c5772 274 SUPERFAMILY SSF53300 61 196 7.79E-7 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily N186_04790 b6de62e1ee986896486db0a482bc7d3d 75 SUPERFAMILY SSF54909 2 73 4.42E-12 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel N186_04790 b6de62e1ee986896486db0a482bc7d3d 75 Pfam PF01037 Lrp/AsnC ligand binding domain 6 73 3.8E-9 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain N186_04790 b6de62e1ee986896486db0a482bc7d3d 75 Gene3D G3DSA:3.30.70.920 2 72 2.8E-18 T 31-10-2018 N186_04330 4d1f033ffbed3eafb387c0b1a6f49315 596 SUPERFAMILY SSF56762 4 581 3.92E-87 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_04330 4d1f033ffbed3eafb387c0b1a6f49315 596 Pfam PF00374 Nickel-dependent hydrogenase 42 123 9.7E-17 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 N186_04330 4d1f033ffbed3eafb387c0b1a6f49315 596 Pfam PF00374 Nickel-dependent hydrogenase 172 581 1.3E-39 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 N186_04330 4d1f033ffbed3eafb387c0b1a6f49315 596 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 572 581 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 N186_04330 4d1f033ffbed3eafb387c0b1a6f49315 596 Gene3D G3DSA:1.10.645.10 4 581 1.3E-190 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_04330 4d1f033ffbed3eafb387c0b1a6f49315 596 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 42 67 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 N186_05060 f992141d82e95c5c84d315801c8a01d8 151 SUPERFAMILY SSF88723 31 141 7.85E-8 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_05060 f992141d82e95c5c84d315801c8a01d8 151 Gene3D G3DSA:3.40.50.1010 25 147 1.2E-8 T 31-10-2018 N186_02575 3187ae7603c173530ff2911b44d0c4cd 153 Gene3D G3DSA:3.90.1170.40 14 152 2.0E-29 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 N186_02575 3187ae7603c173530ff2911b44d0c4cd 153 SUPERFAMILY SSF54690 28 145 2.48E-30 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 N186_02575 3187ae7603c173530ff2911b44d0c4cd 153 Pfam PF02391 MoaE protein 30 125 1.0E-21 T 31-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 N186_06955 179652650902332f4a4b4164c76dcc52 298 SUPERFAMILY SSF161098 65 289 1.7E-57 T 31-10-2018 IPR035906 MetI-like superfamily N186_06955 179652650902332f4a4b4164c76dcc52 298 Gene3D G3DSA:1.10.3720.10 61 296 3.3E-62 T 31-10-2018 IPR035906 MetI-like superfamily N186_06955 179652650902332f4a4b4164c76dcc52 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 289 1.1E-24 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_08020 7f99d334e0df8f3e170c17685de053ff 246 SUPERFAMILY SSF53335 24 220 2.26E-29 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_08020 7f99d334e0df8f3e170c17685de053ff 246 Pfam PF08241 Methyltransferase domain 47 140 2.2E-19 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 N186_08020 7f99d334e0df8f3e170c17685de053ff 246 Gene3D G3DSA:3.40.50.150 15 194 2.4E-29 T 31-10-2018 N186_09455 2ade56ca26def210f1cfb2357f40d183 310 PIRSF PIRSF005355 1 309 5.2E-66 T 31-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 N186_09455 2ade56ca26def210f1cfb2357f40d183 310 Pfam PF01040 UbiA prenyltransferase family 26 274 9.2E-35 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 N186_04215 efa5c63051dd8218a4af08e1ee86f107 213 Gene3D G3DSA:1.10.10.10 143 213 6.8E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04215 efa5c63051dd8218a4af08e1ee86f107 213 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 6 202 6.0E-23 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 N186_04215 efa5c63051dd8218a4af08e1ee86f107 213 Pfam PF13412 Winged helix-turn-helix DNA-binding 149 190 3.9E-5 T 31-10-2018 N186_04215 efa5c63051dd8218a4af08e1ee86f107 213 Gene3D G3DSA:3.40.50.11700 1 141 2.5E-33 T 31-10-2018 N186_04215 efa5c63051dd8218a4af08e1ee86f107 213 SUPERFAMILY SSF46785 139 210 1.53E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_08310 1ab6b76a0e2a81af6d372bf43f3a5ab0 392 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 33 289 1.7E-55 T 31-10-2018 IPR019248 Glucodextranase-like, C-terminal N186_08310 1ab6b76a0e2a81af6d372bf43f3a5ab0 392 SUPERFAMILY SSF49344 33 287 2.71E-45 T 31-10-2018 N186_08310 1ab6b76a0e2a81af6d372bf43f3a5ab0 392 Gene3D G3DSA:1.20.5.340 293 360 8.6E-8 T 31-10-2018 N186_08310 1ab6b76a0e2a81af6d372bf43f3a5ab0 392 Gene3D G3DSA:2.60.40.1190 31 292 3.4E-43 T 31-10-2018 N186_08310 1ab6b76a0e2a81af6d372bf43f3a5ab0 392 SUPERFAMILY SSF58100 306 378 3.66E-6 T 31-10-2018 N186_08310 1ab6b76a0e2a81af6d372bf43f3a5ab0 392 Pfam PF06810 Phage minor structural protein GP20 293 351 1.3E-8 T 31-10-2018 IPR009636 Capsid assembly scaffolding protein GO:0019069 N186_05190 747a7ac10281de04b92d0e59ab941e66 93 PRINTS PR00112 Acylphosphatase signature 6 21 5.0E-5 T 31-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 N186_05190 747a7ac10281de04b92d0e59ab941e66 93 PRINTS PR00112 Acylphosphatase signature 27 52 5.0E-5 T 31-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 N186_05190 747a7ac10281de04b92d0e59ab941e66 93 SUPERFAMILY SSF54975 3 92 8.94E-32 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 N186_05190 747a7ac10281de04b92d0e59ab941e66 93 Gene3D G3DSA:3.30.70.100 1 91 1.8E-36 T 31-10-2018 N186_05190 747a7ac10281de04b92d0e59ab941e66 93 ProSitePatterns PS00151 Acylphosphatase signature 2. 35 51 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 N186_05190 747a7ac10281de04b92d0e59ab941e66 93 Pfam PF00708 Acylphosphatase 8 91 7.6E-29 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 N186_08665 823e70530d9df0a36ab85a29834bd36a 479 Pfam PF12146 Serine aminopeptidase, S33 57 164 6.6E-16 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 N186_08665 823e70530d9df0a36ab85a29834bd36a 479 Gene3D G3DSA:3.40.50.1820 33 252 8.8E-25 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_08665 823e70530d9df0a36ab85a29834bd36a 479 SUPERFAMILY SSF53474 38 220 5.67E-26 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_04470 90f46aa5f1a6496cb2770e3a1d75dbf4 352 SUPERFAMILY SSF140914 14 247 1.02E-37 T 31-10-2018 N186_04470 90f46aa5f1a6496cb2770e3a1d75dbf4 352 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 144 331 3.7E-34 T 31-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 N186_04470 90f46aa5f1a6496cb2770e3a1d75dbf4 352 Hamap MF_00701 DNA primase large subunit PriL [priL]. 16 346 32.568 T 31-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 N186_08305 8c1e14964069d843342fa0f1ddb3e059 395 Pfam PF07690 Major Facilitator Superfamily 34 354 2.2E-20 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_08305 8c1e14964069d843342fa0f1ddb3e059 395 Gene3D G3DSA:1.20.1250.20 216 395 1.1E-9 T 31-10-2018 N186_08305 8c1e14964069d843342fa0f1ddb3e059 395 Gene3D G3DSA:1.20.1250.20 4 200 5.8E-16 T 31-10-2018 N186_08305 8c1e14964069d843342fa0f1ddb3e059 395 SUPERFAMILY SSF103473 1 386 1.83E-37 T 31-10-2018 IPR036259 MFS transporter superfamily N186_08580 47cab269057561a48051c54fda1bb705 283 Pfam PF12698 ABC-2 family transporter protein 87 264 1.8E-10 T 31-10-2018 N186_01295 6d54bffd06d0536461ab1aa73fcffa8b 283 Gene3D G3DSA:1.10.1040.10 157 283 1.4E-16 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 N186_01295 6d54bffd06d0536461ab1aa73fcffa8b 283 SUPERFAMILY SSF51735 1 158 5.23E-38 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_01295 6d54bffd06d0536461ab1aa73fcffa8b 283 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 154 2.1E-34 T 31-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 N186_01295 6d54bffd06d0536461ab1aa73fcffa8b 283 PIRSF PIRSF000103 1 282 2.9E-62 T 31-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 N186_01295 6d54bffd06d0536461ab1aa73fcffa8b 283 SUPERFAMILY SSF48179 162 281 1.59E-14 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 N186_01295 6d54bffd06d0536461ab1aa73fcffa8b 283 Gene3D G3DSA:3.40.50.720 1 156 2.6E-43 T 31-10-2018 N186_01295 6d54bffd06d0536461ab1aa73fcffa8b 283 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 162 280 8.3E-10 T 31-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 N186_03925 a68602e79a93162ccd33415dd1704daf 132 Gene3D G3DSA:2.40.100.20 3 122 1.8E-6 T 31-10-2018 N186_03400 73eebaf88f8a31735832b31bac109d4a 77 SUPERFAMILY SSF46561 4 64 1.44E-17 T 31-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03400 73eebaf88f8a31735832b31bac109d4a 77 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 31-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03400 73eebaf88f8a31735832b31bac109d4a 77 TIGRFAM TIGR00012 L29: ribosomal protein uL29 6 61 1.9E-20 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03400 73eebaf88f8a31735832b31bac109d4a 77 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 15.483 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03400 73eebaf88f8a31735832b31bac109d4a 77 Gene3D G3DSA:1.20.58.1890 1 64 9.9E-22 T 31-10-2018 N186_03400 73eebaf88f8a31735832b31bac109d4a 77 Pfam PF00831 Ribosomal L29 protein 6 60 4.8E-19 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02255 b1a712c0ec2f01e30309cd310ac69378 129 SUPERFAMILY SSF46785 63 125 3.34E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_02255 b1a712c0ec2f01e30309cd310ac69378 129 Pfam PF09339 IclR helix-turn-helix domain 61 107 4.4E-6 T 31-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 N186_02255 b1a712c0ec2f01e30309cd310ac69378 129 Gene3D G3DSA:1.10.10.10 57 129 1.1E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_05085 2c4d09552ab55ccc94f3a3e708ca44ae 252 SUPERFAMILY SSF52540 29 250 2.63E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05085 2c4d09552ab55ccc94f3a3e708ca44ae 252 SMART SM00382 49 224 6.9E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_05085 2c4d09552ab55ccc94f3a3e708ca44ae 252 Gene3D G3DSA:3.40.50.300 27 252 4.8E-52 T 31-10-2018 N186_05085 2c4d09552ab55ccc94f3a3e708ca44ae 252 Pfam PF08423 Rad51 27 251 1.1E-52 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 N186_05510 68fbcaf337336177d1d7392357fa175d 304 Gene3D G3DSA:1.20.81.30 93 203 1.9E-8 T 31-10-2018 N186_05510 68fbcaf337336177d1d7392357fa175d 304 Pfam PF00482 Type II secretion system (T2SS), protein F 104 225 3.1E-16 T 31-10-2018 IPR018076 Type II secretion system F domain N186_02365 d5de72d72313235b0ab971f7c993edbf 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 450 469 4.4E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 155 167 4.4E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 39 53 4.4E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 223 233 4.4E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 373 385 4.4E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 174 191 4.4E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 206 223 4.4E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 SUPERFAMILY SSF55681 21 416 5.72E-113 T 31-10-2018 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 172 241 6.6E-8 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 SUPERFAMILY SSF52954 400 505 6.19E-30 T 31-10-2018 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 21 366 9.3E-124 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 N186_02365 d5de72d72313235b0ab971f7c993edbf 506 Pfam PF03129 Anticodon binding domain 413 502 1.3E-18 T 31-10-2018 IPR004154 Anticodon-binding N186_02365 d5de72d72313235b0ab971f7c993edbf 506 Gene3D G3DSA:3.40.50.800 408 506 2.6E-31 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily N186_03335 7b2c15ecb830cf525b488fc5bd863285 53 Gene3D G3DSA:1.10.1620.10 6 52 7.3E-12 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily N186_03335 7b2c15ecb830cf525b488fc5bd863285 53 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 4 53 15.797 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03335 7b2c15ecb830cf525b488fc5bd863285 53 Pfam PF00832 Ribosomal L39 protein 12 51 1.2E-13 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03335 7b2c15ecb830cf525b488fc5bd863285 53 SUPERFAMILY SSF48662 7 52 8.89E-11 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily N186_03155 2c591b9901bd50feb275d040c585e878 304 Gene3D G3DSA:2.40.30.10 144 223 1.1E-10 T 31-10-2018 N186_03155 2c591b9901bd50feb275d040c585e878 304 SUPERFAMILY SSF50447 144 224 3.28E-10 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily N186_02835 b4c4cdcbb9124406359a830cc4fa0afd 123 Gene3D G3DSA:1.10.1520.20 9 123 6.9E-19 T 31-10-2018 IPR038133 Ribonuclease III superfamily, archaeal N186_02835 b4c4cdcbb9124406359a830cc4fa0afd 123 SUPERFAMILY SSF69065 15 119 3.53E-19 T 31-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 N186_02835 b4c4cdcbb9124406359a830cc4fa0afd 123 Pfam PF11469 Ribonuclease III 17 118 7.0E-17 T 31-10-2018 IPR021568 Ribonuclease III, archaeal N186_03620 54d7da691ebdbcca89aa32acb14228fa 92 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 2 90 14.883 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 N186_03620 54d7da691ebdbcca89aa32acb14228fa 92 Pfam PF09827 CRISPR associated protein Cas2 3 75 1.1E-13 T 31-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 N186_03620 54d7da691ebdbcca89aa32acb14228fa 92 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 3 92 1.8E-13 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 N186_03620 54d7da691ebdbcca89aa32acb14228fa 92 SUPERFAMILY SSF143430 2 80 4.19E-16 T 31-10-2018 N186_03620 54d7da691ebdbcca89aa32acb14228fa 92 Gene3D G3DSA:3.30.70.240 1 68 4.2E-24 T 31-10-2018 N186_08175 730d651243e9e15e081cc5c95ac1beb7 271 Gene3D G3DSA:1.20.120.580 4 134 6.8E-9 T 31-10-2018 IPR037038 Bsu32300-like superfamily N186_08175 730d651243e9e15e081cc5c95ac1beb7 271 Pfam PF01909 Nucleotidyltransferase domain 149 231 3.2E-10 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_08175 730d651243e9e15e081cc5c95ac1beb7 271 Pfam PF01934 Protein of unknown function DUF86 26 110 4.6E-8 T 31-10-2018 IPR008201 Protein of unknown function DUF86 N186_08175 730d651243e9e15e081cc5c95ac1beb7 271 Gene3D G3DSA:3.30.460.10 138 241 1.6E-19 T 31-10-2018 N186_08175 730d651243e9e15e081cc5c95ac1beb7 271 SUPERFAMILY SSF81301 141 236 9.0E-19 T 31-10-2018 N186_01800 17db4f61b729bc06e54cdd1dc8f45b3b 90 Gene3D G3DSA:3.10.20.30 1 90 9.7E-21 T 31-10-2018 IPR012675 Beta-grasp domain superfamily N186_01800 17db4f61b729bc06e54cdd1dc8f45b3b 90 Pfam PF02597 ThiS family 7 90 2.2E-14 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 N186_01800 17db4f61b729bc06e54cdd1dc8f45b3b 90 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 90 2.2E-18 T 31-10-2018 IPR010038 MoaD, archaeal-type N186_01800 17db4f61b729bc06e54cdd1dc8f45b3b 90 SUPERFAMILY SSF54285 4 90 2.99E-15 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp N186_08105 5768c8968d59420180a17c7e309a0159 162 Pfam PF05942 Archaeal PaREP1/PaREP8 family 45 146 1.2E-19 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_00600 688da1276f8f0181eab39e05812ec4ca 249 Gene3D G3DSA:3.40.50.10310 3 242 3.4E-54 T 31-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 N186_00600 688da1276f8f0181eab39e05812ec4ca 249 Pfam PF02633 Creatinine amidohydrolase 8 204 1.9E-48 T 31-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 N186_00600 688da1276f8f0181eab39e05812ec4ca 249 SUPERFAMILY SSF102215 5 205 2.88E-46 T 31-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 N186_07590 eccf64a2555baa644d8e1807f8962fd6 315 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_07590 eccf64a2555baa644d8e1807f8962fd6 315 SUPERFAMILY SSF52540 3 252 2.39E-67 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07590 eccf64a2555baa644d8e1807f8962fd6 315 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 314 3.5E-26 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_07590 eccf64a2555baa644d8e1807f8962fd6 315 SMART SM00382 32 238 1.7E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_07590 eccf64a2555baa644d8e1807f8962fd6 315 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 295 8.2E-21 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 N186_07590 eccf64a2555baa644d8e1807f8962fd6 315 Gene3D G3DSA:3.40.50.300 1 315 2.1E-102 T 31-10-2018 N186_07590 eccf64a2555baa644d8e1807f8962fd6 315 Pfam PF00005 ABC transporter 23 180 6.0E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_01995 bd27470790fdeea7b10dbe48ac68e033 266 Gene3D G3DSA:3.40.1370.10 6 264 2.5E-90 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 N186_01995 bd27470790fdeea7b10dbe48ac68e033 266 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 9 258 2.2E-111 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 N186_01995 bd27470790fdeea7b10dbe48ac68e033 266 Pfam PF00573 Ribosomal protein L4/L1 family 23 258 6.2E-38 T 31-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 N186_01995 bd27470790fdeea7b10dbe48ac68e033 266 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 9 258 43.647 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 N186_01995 bd27470790fdeea7b10dbe48ac68e033 266 SUPERFAMILY SSF52166 9 258 3.01E-67 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 N186_03450 efe942ae6c0e0fcb481e019c81bb05e2 360 Pfam PF04981 NMD3 family 14 242 1.1E-46 T 31-10-2018 IPR007064 Nmd3, N-terminal N186_03660 e39a7bb89d64f9a2aeed66cf39e944e0 249 Gene3D G3DSA:3.30.70.3120 2 236 4.8E-16 T 31-10-2018 N186_03660 e39a7bb89d64f9a2aeed66cf39e944e0 249 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 27 164 9.6E-10 T 31-10-2018 IPR010153 CRISPR-associated protein, Cas5a type N186_04710 7e3f3dbd7b13aebb066f35506b4929f9 165 Pfam PF04008 Adenosine specific kinase 10 163 1.4E-73 T 31-10-2018 IPR007153 Adenosine specific kinase N186_04710 7e3f3dbd7b13aebb066f35506b4929f9 165 SUPERFAMILY SSF103165 6 163 7.72E-70 T 31-10-2018 IPR036902 Ta1353-like superfamily N186_04710 7e3f3dbd7b13aebb066f35506b4929f9 165 Gene3D G3DSA:3.40.1520.10 3 164 2.2E-74 T 31-10-2018 IPR036902 Ta1353-like superfamily N186_03730 e93a57c1680739e1c00ad623efae52dd 365 SUPERFAMILY SSF54001 224 330 9.94E-9 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily N186_03730 e93a57c1680739e1c00ad623efae52dd 365 SMART SM00460 259 314 2.6E-4 T 31-10-2018 IPR002931 Transglutaminase-like N186_04150 5ce8c3fed945e99dd4d871dd92499dcf 86 Pfam PF14697 4Fe-4S dicluster domain 28 82 2.4E-9 T 31-10-2018 N186_04150 5ce8c3fed945e99dd4d871dd92499dcf 86 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 17 85 2.6E-32 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 N186_04150 5ce8c3fed945e99dd4d871dd92499dcf 86 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_04150 5ce8c3fed945e99dd4d871dd92499dcf 86 Gene3D G3DSA:3.30.70.20 12 54 9.5E-7 T 31-10-2018 N186_04150 5ce8c3fed945e99dd4d871dd92499dcf 86 Gene3D G3DSA:3.30.70.20 55 86 3.3E-9 T 31-10-2018 N186_04150 5ce8c3fed945e99dd4d871dd92499dcf 86 SUPERFAMILY SSF54862 21 84 8.12E-23 T 31-10-2018 N186_03270 8e273a3b4ae71a313004595f9bfb5c9f 98 SUPERFAMILY SSF50104 1 89 6.02E-24 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily N186_03270 8e273a3b4ae71a313004595f9bfb5c9f 98 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 80 28.57 T 31-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 N186_03270 8e273a3b4ae71a313004595f9bfb5c9f 98 Gene3D G3DSA:2.30.30.30 4 87 1.7E-35 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 N186_05170 beea3b0bc06a094231f0f0b5df90d9d1 364 Gene3D G3DSA:3.20.20.140 39 299 1.7E-19 T 31-10-2018 N186_05170 beea3b0bc06a094231f0f0b5df90d9d1 364 Pfam PF01979 Amidohydrolase family 35 299 1.3E-5 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 N186_05170 beea3b0bc06a094231f0f0b5df90d9d1 364 SUPERFAMILY SSF51556 37 298 1.56E-25 T 31-10-2018 IPR032466 Metal-dependent hydrolase N186_00725 299a959a444e23f17d9079e5a8bcc37c 399 SUPERFAMILY SSF103473 7 388 3.92E-48 T 31-10-2018 IPR036259 MFS transporter superfamily N186_00725 299a959a444e23f17d9079e5a8bcc37c 399 Gene3D G3DSA:1.20.1250.20 4 395 9.2E-45 T 31-10-2018 N186_00725 299a959a444e23f17d9079e5a8bcc37c 399 Pfam PF07690 Major Facilitator Superfamily 13 360 3.2E-30 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_00830 366c783e93a5b4a8f051ba2aa2a9ee77 283 Gene3D G3DSA:1.20.144.10 87 178 1.4E-19 T 31-10-2018 N186_00830 366c783e93a5b4a8f051ba2aa2a9ee77 283 Pfam PF01569 PAP2 superfamily 61 167 9.3E-16 T 31-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase N186_00830 366c783e93a5b4a8f051ba2aa2a9ee77 283 SMART SM00014 58 164 5.2E-22 T 31-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase N186_00830 366c783e93a5b4a8f051ba2aa2a9ee77 283 SUPERFAMILY SSF48317 26 172 1.96E-27 T 31-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily N186_07285 c5593ec6601fd937076ff4b863e0214e 258 Pfam PF01061 ABC-2 type transporter 10 221 4.0E-17 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 N186_07285 c5593ec6601fd937076ff4b863e0214e 258 PIRSF PIRSF006648 2 256 9.3E-28 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 N186_05740 c30691d5aa3a1cd482af77652c0edd1d 312 SUPERFAMILY SSF51658 48 294 1.23E-29 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily N186_05740 c30691d5aa3a1cd482af77652c0edd1d 312 Pfam PF01261 Xylose isomerase-like TIM barrel 93 229 1.1E-13 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain N186_05740 c30691d5aa3a1cd482af77652c0edd1d 312 Gene3D G3DSA:3.20.20.150 16 309 8.5E-35 T 31-10-2018 N186_09700 1b67025c851b97388ec2b46c81d74a13 204 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 48 177 2.5E-23 T 31-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family N186_09700 1b67025c851b97388ec2b46c81d74a13 204 SUPERFAMILY SSF54001 48 196 4.32E-27 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily N186_09700 1b67025c851b97388ec2b46c81d74a13 204 Gene3D G3DSA:3.90.1720.10 51 176 9.9E-14 T 31-10-2018 N186_07720 d64669428a6ffcb47007e161235e399e 427 SUPERFAMILY SSF103473 15 423 1.15E-59 T 31-10-2018 IPR036259 MFS transporter superfamily N186_07720 d64669428a6ffcb47007e161235e399e 427 Gene3D G3DSA:1.20.1250.20 227 425 4.4E-23 T 31-10-2018 N186_07720 d64669428a6ffcb47007e161235e399e 427 Pfam PF13347 MFS/sugar transport protein 19 398 2.6E-30 T 31-10-2018 N186_07720 d64669428a6ffcb47007e161235e399e 427 Gene3D G3DSA:1.20.1250.20 11 204 4.9E-27 T 31-10-2018 N186_07045 87c91932b354586e098eb3213f04c615 152 SUPERFAMILY SSF52833 23 132 6.94E-10 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_07045 87c91932b354586e098eb3213f04c615 152 Gene3D G3DSA:3.40.30.10 19 143 4.5E-8 T 31-10-2018 N186_05950 7b966c4809a3c81bb1e2c7a25cc590db 745 SMART SM00487 53 254 1.8E-38 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain N186_05950 7b966c4809a3c81bb1e2c7a25cc590db 745 Pfam PF09369 Domain of unknown function (DUF1998) 630 703 1.6E-14 T 31-10-2018 IPR018973 DEAD/DEAH-box helicase, putative N186_05950 7b966c4809a3c81bb1e2c7a25cc590db 745 SMART SM00490 292 373 2.3E-22 T 31-10-2018 IPR001650 Helicase, C-terminal N186_05950 7b966c4809a3c81bb1e2c7a25cc590db 745 Gene3D G3DSA:3.40.50.300 252 413 4.4E-29 T 31-10-2018 N186_05950 7b966c4809a3c81bb1e2c7a25cc590db 745 Gene3D G3DSA:3.40.50.300 38 241 6.1E-46 T 31-10-2018 N186_05950 7b966c4809a3c81bb1e2c7a25cc590db 745 Pfam PF00271 Helicase conserved C-terminal domain 269 373 1.1E-18 T 31-10-2018 IPR001650 Helicase, C-terminal N186_05950 7b966c4809a3c81bb1e2c7a25cc590db 745 Pfam PF00270 DEAD/DEAH box helicase 59 224 8.8E-29 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 N186_05950 7b966c4809a3c81bb1e2c7a25cc590db 745 SUPERFAMILY SSF52540 65 385 6.46E-54 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09515 74ae0f9d9a3b4dc303287636cc8ef8ff 220 Pfam PF04474 Protein of unknown function (DUF554) 2 217 2.3E-68 T 31-10-2018 IPR007563 Protein of unknown function DUF554 N186_05490 5911568ebbd5e7895a240d39e548c057 136 Pfam PF01989 Protein of unknown function DUF126 26 105 4.9E-30 T 31-10-2018 IPR002840 Aconitase X swivel domain, putative N186_05490 5911568ebbd5e7895a240d39e548c057 136 SUPERFAMILY SSF52016 3 121 5.41E-38 T 31-10-2018 N186_05490 5911568ebbd5e7895a240d39e548c057 136 Gene3D G3DSA:3.50.30.10 2 131 5.7E-38 T 31-10-2018 N186_07120 ed7151e172c928719095901b5eaa1ff1 272 Gene3D G3DSA:3.40.50.10320 18 272 6.6E-79 T 31-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 N186_07120 ed7151e172c928719095901b5eaa1ff1 272 Pfam PF02585 GlcNAc-PI de-N-acetylase 46 172 1.4E-27 T 31-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 N186_07120 ed7151e172c928719095901b5eaa1ff1 272 SUPERFAMILY SSF102588 44 264 1.96E-51 T 31-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 N186_07705 2b48e2370f9bc164a41a5f52739b5568 325 Gene3D G3DSA:3.40.50.300 3 236 5.5E-75 T 31-10-2018 N186_07705 2b48e2370f9bc164a41a5f52739b5568 325 SUPERFAMILY SSF52540 8 228 2.36E-71 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07705 2b48e2370f9bc164a41a5f52739b5568 325 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 15 307 7.4E-117 T 31-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 N186_07705 2b48e2370f9bc164a41a5f52739b5568 325 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_07705 2b48e2370f9bc164a41a5f52739b5568 325 SMART SM00382 32 224 7.0E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_07705 2b48e2370f9bc164a41a5f52739b5568 325 Pfam PF13732 Domain of unknown function (DUF4162) 221 305 3.3E-8 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 N186_07705 2b48e2370f9bc164a41a5f52739b5568 325 Pfam PF00005 ABC transporter 24 166 3.8E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_04480 98194680bff854046e18f5faf339f369 99 TIGRFAM TIGR01384 TFS_arch: transcription factor S 1 98 4.7E-22 T 31-10-2018 IPR006288 Transcription factor S GO:0006355 N186_04480 98194680bff854046e18f5faf339f369 99 SUPERFAMILY SSF57783 37 98 6.8E-20 T 31-10-2018 N186_04480 98194680bff854046e18f5faf339f369 99 Pfam PF01096 Transcription factor S-II (TFIIS) 58 96 6.3E-17 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 N186_04480 98194680bff854046e18f5faf339f369 99 Gene3D G3DSA:2.20.25.10 45 99 1.4E-20 T 31-10-2018 N186_04480 98194680bff854046e18f5faf339f369 99 PIRSF PIRSF005586 1 99 2.6E-24 T 31-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 N186_04480 98194680bff854046e18f5faf339f369 99 SMART SM00440 58 97 9.5E-17 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 N186_08125 d532e49d21fe64f7c08845c9543b0be9 164 Gene3D G3DSA:1.20.120.330 52 163 3.3E-18 T 31-10-2018 N186_08125 d532e49d21fe64f7c08845c9543b0be9 164 Pfam PF05942 Archaeal PaREP1/PaREP8 family 52 155 5.2E-25 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_02040 a2af068463fcc6813a81e892e1573dca 320 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 91 236 1.9E-26 T 31-10-2018 IPR010172 CRISPR-associated protein, TM1791 N186_02040 a2af068463fcc6813a81e892e1573dca 320 Pfam PF03787 RAMP superfamily 111 311 2.5E-11 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein N186_01845 9b67c9ae1db0eab2c5acd0fe6ae4c08f 256 Gene3D G3DSA:3.40.50.10900 1 255 1.8E-52 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily N186_01845 9b67c9ae1db0eab2c5acd0fe6ae4c08f 256 Pfam PF09754 PAC2 family 24 234 8.7E-37 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 N186_01845 9b67c9ae1db0eab2c5acd0fe6ae4c08f 256 SUPERFAMILY SSF159659 9 240 1.7E-29 T 31-10-2018 N186_06215 947a1cab64b384c379dbbbfdf08f5c85 176 Gene3D G3DSA:1.10.1760.20 2 174 4.3E-27 T 31-10-2018 N186_06215 947a1cab64b384c379dbbbfdf08f5c85 176 Pfam PF12822 ECF transporter, substrate-specific component 7 164 1.3E-7 T 31-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 N186_00845 33821559a269d4fb161ee37f7cab0709 193 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 3.9E-13 T 31-10-2018 N186_00845 33821559a269d4fb161ee37f7cab0709 193 SMART SM00746 151 187 1.5E-5 T 31-10-2018 IPR011017 TRASH domain N186_00845 33821559a269d4fb161ee37f7cab0709 193 Pfam PF08394 Archaeal TRASH domain 151 187 1.2E-7 T 31-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal N186_00845 33821559a269d4fb161ee37f7cab0709 193 SMART SM00344 2 103 8.6E-15 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 N186_00845 33821559a269d4fb161ee37f7cab0709 193 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.0E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_00845 33821559a269d4fb161ee37f7cab0709 193 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.0E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_00845 33821559a269d4fb161ee37f7cab0709 193 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.0E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 N186_00845 33821559a269d4fb161ee37f7cab0709 193 SUPERFAMILY SSF46785 1 61 1.24E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_00845 33821559a269d4fb161ee37f7cab0709 193 Gene3D G3DSA:1.10.10.10 2 52 1.0E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_00845 33821559a269d4fb161ee37f7cab0709 193 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 31-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site N186_00860 d6a88c88d7dd1bef731b9fcc54f986cb 78 SUPERFAMILY SSF89447 2 68 1.01E-8 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_00860 d6a88c88d7dd1bef731b9fcc54f986cb 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 48 1.3E-5 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_00860 d6a88c88d7dd1bef731b9fcc54f986cb 78 SMART SM00966 5 50 9.9E-5 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08705 34dd5d8319d58f815bd9784f7cb13ec4 535 SUPERFAMILY SSF52540 133 512 8.01E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08705 34dd5d8319d58f815bd9784f7cb13ec4 535 Pfam PF01935 Domain of unknown function DUF87 141 297 1.2E-13 T 31-10-2018 IPR002789 Helicase HerA, central domain N186_08705 34dd5d8319d58f815bd9784f7cb13ec4 535 Gene3D G3DSA:3.40.50.300 330 520 9.3E-29 T 31-10-2018 N186_08705 34dd5d8319d58f815bd9784f7cb13ec4 535 Gene3D G3DSA:3.40.50.300 114 209 2.8E-11 T 31-10-2018 N186_06000 d6b576a638f956d6193a74e24fcf00c7 280 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 46 194 4.3E-32 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 N186_06000 d6b576a638f956d6193a74e24fcf00c7 280 SUPERFAMILY SSF52518 9 256 7.67E-78 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold N186_06000 d6b576a638f956d6193a74e24fcf00c7 280 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 198 255 4.5E-17 T 31-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal N186_06000 d6b576a638f956d6193a74e24fcf00c7 280 Gene3D G3DSA:3.40.50.970 76 220 2.5E-24 T 31-10-2018 N186_06000 d6b576a638f956d6193a74e24fcf00c7 280 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 13 248 8.0E-104 T 31-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate N186_06875 f384bdb758de7308c2dc449127e0f30a 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 206 6.1E-10 T 31-10-2018 N186_06875 f384bdb758de7308c2dc449127e0f30a 241 Gene3D G3DSA:3.40.50.1000 11 211 2.7E-19 T 31-10-2018 IPR023214 HAD superfamily N186_06875 f384bdb758de7308c2dc449127e0f30a 241 SUPERFAMILY SSF56784 10 236 4.2E-25 T 31-10-2018 IPR036412 HAD-like superfamily N186_07040 6f8685405ace7b031472c444bbec3cec 313 Gene3D G3DSA:3.90.25.10 229 313 3.5E-24 T 31-10-2018 N186_07040 6f8685405ace7b031472c444bbec3cec 313 Gene3D G3DSA:3.90.25.10 176 228 7.1E-12 T 31-10-2018 N186_07040 6f8685405ace7b031472c444bbec3cec 313 Gene3D G3DSA:3.40.50.720 1 175 2.0E-57 T 31-10-2018 N186_07040 6f8685405ace7b031472c444bbec3cec 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 233 1.6E-53 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 N186_07040 6f8685405ace7b031472c444bbec3cec 313 SUPERFAMILY SSF51735 2 303 6.8E-86 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_07820 4918733ad04dcb60e95574ee2a9589f1 280 Gene3D G3DSA:1.10.287.950 31 160 3.1E-5 T 31-10-2018 N186_07820 4918733ad04dcb60e95574ee2a9589f1 280 SUPERFAMILY SSF52980 9 276 1.34E-19 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_07820 4918733ad04dcb60e95574ee2a9589f1 280 Pfam PF12644 Protein of unknown function (DUF3782) 127 201 1.9E-8 T 31-10-2018 IPR024271 Protein of unknown function DUF3782 N186_07820 4918733ad04dcb60e95574ee2a9589f1 280 Pfam PF07788 PD-(D/E)XK nuclease superfamily 204 271 1.3E-9 T 31-10-2018 IPR012431 PD-(D/E)XK nuclease N186_06330 e6b9a47be4e09cc6a19b6e6524845a00 461 SUPERFAMILY SSF55831 152 371 3.4E-33 T 31-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 N186_06330 e6b9a47be4e09cc6a19b6e6524845a00 461 Gene3D G3DSA:3.30.572.10 143 401 3.6E-25 T 31-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 N186_06330 e6b9a47be4e09cc6a19b6e6524845a00 461 Pfam PF00303 Thymidylate synthase 237 377 2.3E-11 T 31-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 N186_09405 5c8952879f184b14d15239faffcb53bc 351 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 336 4.5E-35 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 N186_06095 69dcc16e496f6c57ed07cd9ca9a0fcdf 296 SMART SM00079 70 295 4.3E-4 T 31-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 N186_06095 69dcc16e496f6c57ed07cd9ca9a0fcdf 296 Gene3D G3DSA:3.40.190.10 68 284 3.5E-64 T 31-10-2018 N186_06095 69dcc16e496f6c57ed07cd9ca9a0fcdf 296 SUPERFAMILY SSF53850 33 286 6.34E-62 T 31-10-2018 N186_06095 69dcc16e496f6c57ed07cd9ca9a0fcdf 296 Gene3D G3DSA:3.40.190.10 158 250 3.5E-64 T 31-10-2018 N186_06095 69dcc16e496f6c57ed07cd9ca9a0fcdf 296 SMART SM00062 70 296 3.1E-63 T 31-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF N186_06095 69dcc16e496f6c57ed07cd9ca9a0fcdf 296 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 93 106 - T 31-10-2018 IPR018313 Solute-binding protein family 3, conserved site N186_06095 69dcc16e496f6c57ed07cd9ca9a0fcdf 296 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 71 294 4.6E-57 T 31-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF N186_00310 1e2e408edc8655320141aca551da95ea 713 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 223 401 2.4E-13 T 31-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 N186_00310 1e2e408edc8655320141aca551da95ea 713 SUPERFAMILY SSF51569 219 391 1.22E-14 T 31-10-2018 N186_00310 1e2e408edc8655320141aca551da95ea 713 Gene3D G3DSA:3.20.20.70 214 456 3.5E-19 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_05800 a750b0a1e0d993f6616805851bc41b9c 170 SUPERFAMILY SSF55021 99 167 8.66E-10 T 31-10-2018 N186_05800 a750b0a1e0d993f6616805851bc41b9c 170 PIRSF PIRSF004897 5 170 1.6E-39 T 31-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type N186_05800 a750b0a1e0d993f6616805851bc41b9c 170 Gene3D G3DSA:3.30.70.260 99 170 7.9E-8 T 31-10-2018 N186_08495 e0efd21a4b9b46dfce55071f5a52fb27 169 SUPERFAMILY SSF54862 5 138 1.51E-34 T 31-10-2018 N186_08495 e0efd21a4b9b46dfce55071f5a52fb27 169 Gene3D G3DSA:3.30.70.20 61 114 2.3E-22 T 31-10-2018 N186_08495 e0efd21a4b9b46dfce55071f5a52fb27 169 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site N186_08495 e0efd21a4b9b46dfce55071f5a52fb27 169 Pfam PF13247 4Fe-4S dicluster domain 51 129 3.8E-12 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain N186_08495 e0efd21a4b9b46dfce55071f5a52fb27 169 Gene3D G3DSA:3.30.70.20 9 131 2.3E-22 T 31-10-2018 N186_00575 2c04bb79091e0db561aa3069ecf89297 470 Pfam PF13337 Putative ATP-dependent Lon protease 12 464 3.1E-140 T 31-10-2018 IPR014061 Conserved hypothetical protein CHP02688 N186_00575 2c04bb79091e0db561aa3069ecf89297 470 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 9 456 2.4E-130 T 31-10-2018 IPR014061 Conserved hypothetical protein CHP02688 N186_05975 fde638b8f2dd1d85880070548489f4d1 266 Pfam PF04055 Radical SAM superfamily 35 136 3.4E-14 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_05975 fde638b8f2dd1d85880070548489f4d1 266 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 12 215 2.1E-39 T 31-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein N186_05975 fde638b8f2dd1d85880070548489f4d1 266 Pfam PF13353 4Fe-4S single cluster domain 27 135 2.1E-9 T 31-10-2018 N186_05975 fde638b8f2dd1d85880070548489f4d1 266 SUPERFAMILY SSF102114 34 242 2.88E-18 T 31-10-2018 N186_05975 fde638b8f2dd1d85880070548489f4d1 266 Gene3D G3DSA:3.20.20.70 11 255 1.0E-22 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_00855 b7a400e5f843d86b68ab8ef2142786ff 149 Pfam PF01850 PIN domain 4 118 1.3E-14 T 31-10-2018 IPR002716 PIN domain N186_00855 b7a400e5f843d86b68ab8ef2142786ff 149 SUPERFAMILY SSF88723 1 118 3.36E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_00855 b7a400e5f843d86b68ab8ef2142786ff 149 Gene3D G3DSA:3.40.50.1010 1 129 1.9E-10 T 31-10-2018 N186_08340 d88c98d16cedf13300b92e93c3adbd2e 250 Pfam PF04240 Carotenoid biosynthesis protein 36 222 2.1E-33 T 31-10-2018 IPR007354 Carotene biosynthesis associated membrane protein N186_07320 6c644108795cc7814b89399307ac3a2c 493 SUPERFAMILY SSF102114 171 387 6.77E-17 T 31-10-2018 N186_07320 6c644108795cc7814b89399307ac3a2c 493 Pfam PF04055 Radical SAM superfamily 195 380 1.0E-16 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_07320 6c644108795cc7814b89399307ac3a2c 493 Gene3D G3DSA:3.80.30.20 191 427 4.1E-29 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe N186_07320 6c644108795cc7814b89399307ac3a2c 493 SMART SM00729 191 418 3.9E-17 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_05100 1a46934f2697517baeb68f6dc19cf68e 232 SUPERFAMILY SSF54631 111 167 1.29E-5 T 31-10-2018 N186_08865 c88269907d37d91cd32b34c76c74a110 80 Gene3D G3DSA:2.10.260.10 2 42 3.3E-14 T 31-10-2018 N186_08865 c88269907d37d91cd32b34c76c74a110 80 SMART SM00966 4 50 3.4E-13 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08865 c88269907d37d91cd32b34c76c74a110 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 47 5.3E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08865 c88269907d37d91cd32b34c76c74a110 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 45 4.9E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08865 c88269907d37d91cd32b34c76c74a110 80 SUPERFAMILY SSF89447 4 54 8.55E-12 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_01955 82e2fdc736425e21d3a002d486ba2afa 295 Gene3D G3DSA:3.90.105.20 113 192 5.2E-57 T 31-10-2018 N186_01955 82e2fdc736425e21d3a002d486ba2afa 295 Pfam PF00466 Ribosomal protein L10 14 111 2.8E-21 T 31-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 N186_01955 82e2fdc736425e21d3a002d486ba2afa 295 Gene3D G3DSA:3.30.70.1730 27 214 5.2E-57 T 31-10-2018 N186_01955 82e2fdc736425e21d3a002d486ba2afa 295 SUPERFAMILY SSF160369 14 143 7.59E-20 T 31-10-2018 N186_01955 82e2fdc736425e21d3a002d486ba2afa 295 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 11 289 32.613 T 31-10-2018 IPR022909 50S ribosomal protein L10, archaea N186_01900 21b9d0a04030a7b9ba29c5552c372a84 603 Pfam PF03065 Glycosyl hydrolase family 57 110 442 9.4E-33 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 N186_01900 21b9d0a04030a7b9ba29c5552c372a84 603 Gene3D G3DSA:3.20.110.20 148 464 3.4E-45 T 31-10-2018 N186_01900 21b9d0a04030a7b9ba29c5552c372a84 603 SUPERFAMILY SSF88713 105 436 1.74E-45 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 N186_09470 1f75253e1673d87491eacf1171331234 158 Gene3D G3DSA:3.40.630.30 3 157 6.5E-24 T 31-10-2018 N186_09470 1f75253e1673d87491eacf1171331234 158 SUPERFAMILY SSF55729 4 157 3.27E-25 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase N186_09470 1f75253e1673d87491eacf1171331234 158 Pfam PF00583 Acetyltransferase (GNAT) family 43 127 1.4E-19 T 31-10-2018 IPR000182 GNAT domain N186_08180 8a9bb1628ade6d0b1e3dc15f28bbda57 410 SUPERFAMILY SSF53448 56 300 5.04E-59 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_08180 8a9bb1628ade6d0b1e3dc15f28bbda57 410 Gene3D G3DSA:3.90.550.10 50 265 3.5E-47 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_08180 8a9bb1628ade6d0b1e3dc15f28bbda57 410 Pfam PF13641 Glycosyltransferase like family 2 60 285 3.0E-41 T 31-10-2018 N186_07990 1b1dbbc6a5eb99aaba3be728af18e32f 344 Gene3D G3DSA:3.90.550.10 5 244 1.1E-27 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_07990 1b1dbbc6a5eb99aaba3be728af18e32f 344 Pfam PF00535 Glycosyl transferase family 2 36 197 2.5E-15 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 N186_07990 1b1dbbc6a5eb99aaba3be728af18e32f 344 SUPERFAMILY SSF53448 35 300 8.44E-31 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_03630 cea642675f10e26990ac46aced47eeab 117 Gene3D G3DSA:3.90.320.10 8 117 8.7E-8 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal N186_03630 cea642675f10e26990ac46aced47eeab 117 Pfam PF06023 CRISPR-associated exonuclease Csa1 2 116 9.1E-37 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 N186_03630 cea642675f10e26990ac46aced47eeab 117 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 2 116 6.8E-40 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 N186_09730 23d74e321bda6772b7beb351f66ae030 147 Pfam PF00324 Amino acid permease 29 131 8.8E-10 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 N186_09730 23d74e321bda6772b7beb351f66ae030 147 Gene3D G3DSA:1.20.1740.10 12 147 1.1E-20 T 31-10-2018 N186_09625 49b339fe6e5a1c87ae3971eb91428fb8 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 14 300 3.1E-33 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 N186_04450 b7d33f56fef4bd6a67665c48c62d1275 185 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 93 172 2.7E-27 T 31-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 N186_04450 b7d33f56fef4bd6a67665c48c62d1275 185 Gene3D G3DSA:3.40.1170.20 1 89 9.6E-22 T 31-10-2018 N186_04450 b7d33f56fef4bd6a67665c48c62d1275 185 PIRSF PIRSF005285 9 185 4.3E-47 T 31-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 N186_04450 b7d33f56fef4bd6a67665c48c62d1275 185 TIGRFAM TIGR00324 endA: tRNA-intron lyase 49 183 8.1E-33 T 31-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 N186_04450 b7d33f56fef4bd6a67665c48c62d1275 185 SUPERFAMILY SSF53032 91 176 1.66E-25 T 31-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 N186_04450 b7d33f56fef4bd6a67665c48c62d1275 185 SUPERFAMILY SSF55267 7 87 2.16E-10 T 31-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 N186_04450 b7d33f56fef4bd6a67665c48c62d1275 185 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 7 83 2.0E-12 T 31-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 N186_04450 b7d33f56fef4bd6a67665c48c62d1275 185 Gene3D G3DSA:3.40.1350.10 92 185 3.8E-30 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 N186_08825 f4db72b58f8af83e272cfae8acce0e56 513 Gene3D G3DSA:3.40.50.300 44 230 4.0E-7 T 31-10-2018 N186_08825 f4db72b58f8af83e272cfae8acce0e56 513 SUPERFAMILY SSF52540 37 223 1.25E-7 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_00915 aeae3733caa5b6c2c01046e0a99ea06e 160 Pfam PF09821 C-terminal AAA-associated domain 39 151 4.6E-20 T 31-10-2018 IPR018632 C-terminal AAA-associated domain N186_08560 dfafa22543e658b150e472a61b3fc277 631 SUPERFAMILY SSF54292 2 97 9.4E-21 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 N186_08560 dfafa22543e658b150e472a61b3fc277 631 Gene3D G3DSA:2.40.50.570 115 197 4.2E-13 T 31-10-2018 N186_08560 dfafa22543e658b150e472a61b3fc277 631 Gene3D G3DSA:3.30.420.480 198 377 1.3E-56 T 31-10-2018 N186_08560 dfafa22543e658b150e472a61b3fc277 631 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 83 1.3E-7 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 N186_08560 dfafa22543e658b150e472a61b3fc277 631 Pfam PF14574 Domain of unknown function (DUF4445) 200 609 6.8E-138 T 31-10-2018 IPR027980 Protein of unknown function DUF4445 N186_08560 dfafa22543e658b150e472a61b3fc277 631 Gene3D G3DSA:3.10.20.30 1 103 1.8E-22 T 31-10-2018 IPR012675 Beta-grasp domain superfamily N186_08560 dfafa22543e658b150e472a61b3fc277 631 SUPERFAMILY SSF53067 201 538 4.57E-9 T 31-10-2018 N186_05540 1167986fba9064da959265bf055dbb8f 87 SUPERFAMILY SSF159468 6 83 1.57E-5 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_05540 1167986fba9064da959265bf055dbb8f 87 Gene3D G3DSA:3.40.50.10580 2 87 4.5E-7 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_02305 41415321d387db9fa5e2bed50b669421 120 SUPERFAMILY SSF52080 5 119 1.57E-19 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily N186_02305 41415321d387db9fa5e2bed50b669421 120 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 4 120 24.54 T 31-10-2018 IPR022947 Ribosomal protein L18e, archaea N186_02305 41415321d387db9fa5e2bed50b669421 120 Gene3D G3DSA:3.100.10.10 5 120 5.5E-30 T 31-10-2018 N186_06655 c17381e47d79208bf3434cc304846f7e 250 Pfam PF13580 SIS domain 11 146 4.0E-41 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 N186_06655 c17381e47d79208bf3434cc304846f7e 250 SUPERFAMILY SSF53697 7 213 2.43E-24 T 31-10-2018 N186_06655 c17381e47d79208bf3434cc304846f7e 250 Gene3D G3DSA:3.40.50.10490 5 244 7.1E-85 T 31-10-2018 N186_06220 5c5ca014ef0867af8f93d4cba8cd39b1 886 Gene3D G3DSA:3.40.50.300 266 415 6.6E-23 T 31-10-2018 N186_06220 5c5ca014ef0867af8f93d4cba8cd39b1 886 SMART SM00490 301 391 1.5E-16 T 31-10-2018 IPR001650 Helicase, C-terminal N186_06220 5c5ca014ef0867af8f93d4cba8cd39b1 886 PIRSF PIRSF037307 6 886 4.2E-275 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 N186_06220 5c5ca014ef0867af8f93d4cba8cd39b1 886 Pfam PF08494 DEAD/H associated 658 844 1.7E-57 T 31-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 N186_06220 5c5ca014ef0867af8f93d4cba8cd39b1 886 Gene3D G3DSA:3.40.50.300 13 237 8.1E-53 T 31-10-2018 N186_06220 5c5ca014ef0867af8f93d4cba8cd39b1 886 SMART SM00487 32 256 3.5E-31 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain N186_06220 5c5ca014ef0867af8f93d4cba8cd39b1 886 SUPERFAMILY SSF52540 48 398 4.66E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_06220 5c5ca014ef0867af8f93d4cba8cd39b1 886 Pfam PF00270 DEAD/DEAH box helicase 37 221 1.8E-27 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 N186_06220 5c5ca014ef0867af8f93d4cba8cd39b1 886 Pfam PF00271 Helicase conserved C-terminal domain 278 387 1.0E-15 T 31-10-2018 IPR001650 Helicase, C-terminal N186_04030 547210f20ea76a12b16be169ec8211cb 135 Gene3D G3DSA:3.40.50.1010 1 128 1.5E-6 T 31-10-2018 N186_04030 547210f20ea76a12b16be169ec8211cb 135 Pfam PF01850 PIN domain 10 125 2.3E-8 T 31-10-2018 IPR002716 PIN domain N186_04030 547210f20ea76a12b16be169ec8211cb 135 SUPERFAMILY SSF88723 6 131 1.34E-13 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_07980 8fb6475f38aff1823a15127b91f37b92 192 Pfam PF01850 PIN domain 5 167 1.7E-7 T 31-10-2018 IPR002716 PIN domain N186_07980 8fb6475f38aff1823a15127b91f37b92 192 SUPERFAMILY SSF88723 5 172 2.63E-8 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_03550 a5b757578e705748e0ceb6640bd3d3f5 234 Pfam PF00696 Amino acid kinase family 8 210 3.5E-28 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 N186_03550 a5b757578e705748e0ceb6640bd3d3f5 234 SUPERFAMILY SSF53633 8 225 2.49E-35 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily N186_03550 a5b757578e705748e0ceb6640bd3d3f5 234 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 9 226 1.9E-59 T 31-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 N186_03550 a5b757578e705748e0ceb6640bd3d3f5 234 PIRSF PIRSF005650 1 232 9.6E-44 T 31-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 N186_03550 a5b757578e705748e0ceb6640bd3d3f5 234 Gene3D G3DSA:3.40.1160.10 4 233 8.0E-46 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily N186_09630 5af259ea2e13c15c5ebb53cd87ca0564 450 SUPERFAMILY SSF53822 74 439 3.53E-67 T 31-10-2018 IPR028082 Periplasmic binding protein-like I N186_09630 5af259ea2e13c15c5ebb53cd87ca0564 450 Pfam PF13458 Periplasmic binding protein 79 417 6.6E-43 T 31-10-2018 IPR028081 Leucine-binding protein domain N186_09630 5af259ea2e13c15c5ebb53cd87ca0564 450 Gene3D G3DSA:3.40.50.2300 81 402 8.7E-61 T 31-10-2018 N186_09630 5af259ea2e13c15c5ebb53cd87ca0564 450 Gene3D G3DSA:3.40.50.2300 198 333 8.7E-61 T 31-10-2018 N186_03945 78fd69c28bfb9f2d08bc8666b3edb2d8 300 Pfam PF12679 ABC-2 family transporter protein 5 295 3.4E-43 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 N186_06540 06953eeffb77603b766fd7e07577c413 111 Gene3D G3DSA:3.40.630.30 3 109 3.3E-22 T 31-10-2018 N186_06540 06953eeffb77603b766fd7e07577c413 111 Pfam PF00583 Acetyltransferase (GNAT) family 14 99 1.4E-15 T 31-10-2018 IPR000182 GNAT domain N186_06540 06953eeffb77603b766fd7e07577c413 111 SUPERFAMILY SSF55729 16 104 1.18E-22 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase N186_07525 cc91e361317d063ac29a9c1cb2e61925 277 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 273 13.061 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07525 cc91e361317d063ac29a9c1cb2e61925 277 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 188 216 3.1E-23 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07525 cc91e361317d063ac29a9c1cb2e61925 277 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 13 40 3.1E-23 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07525 cc91e361317d063ac29a9c1cb2e61925 277 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 136 162 3.1E-23 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07525 cc91e361317d063ac29a9c1cb2e61925 277 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 118 136 3.1E-23 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_07525 cc91e361317d063ac29a9c1cb2e61925 277 Pfam PF00902 Sec-independent protein translocase protein (TatC) 23 256 1.5E-41 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 N186_09295 0546ee47beabd4ec526901d578b6c189 137 Gene3D G3DSA:3.40.50.1010 1 134 2.2E-33 T 31-10-2018 N186_09295 0546ee47beabd4ec526901d578b6c189 137 SUPERFAMILY SSF88723 4 125 7.29E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_09295 0546ee47beabd4ec526901d578b6c189 137 Pfam PF01850 PIN domain 4 120 2.3E-7 T 31-10-2018 IPR002716 PIN domain N186_02300 531ec2456bf02fccc9d93b69e45ae71c 152 PIRSF PIRSF002181 1 151 6.8E-37 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 N186_02300 531ec2456bf02fccc9d93b69e45ae71c 152 SUPERFAMILY SSF52161 4 145 2.75E-37 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 N186_02300 531ec2456bf02fccc9d93b69e45ae71c 152 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 8 148 2.9E-46 T 31-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 N186_02300 531ec2456bf02fccc9d93b69e45ae71c 152 ProSitePatterns PS00783 Ribosomal protein L13 signature. 87 110 - T 31-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 N186_02300 531ec2456bf02fccc9d93b69e45ae71c 152 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 7 139 21.693 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 N186_02300 531ec2456bf02fccc9d93b69e45ae71c 152 Gene3D G3DSA:3.90.1180.10 2 148 8.3E-48 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 N186_02300 531ec2456bf02fccc9d93b69e45ae71c 152 Pfam PF00572 Ribosomal protein L13 9 116 2.3E-11 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 N186_08005 7d5babe643833d345e055e22d1216834 375 Pfam PF00534 Glycosyl transferases group 1 169 336 3.3E-13 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 N186_08005 7d5babe643833d345e055e22d1216834 375 SUPERFAMILY SSF53756 30 368 2.56E-33 T 31-10-2018 N186_08005 7d5babe643833d345e055e22d1216834 375 Gene3D G3DSA:3.40.50.2000 154 349 3.6E-22 T 31-10-2018 N186_01890 4af187fce965584d16d3a4ebce802240 453 Gene3D G3DSA:3.40.50.10180 28 279 2.4E-155 T 31-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 N186_01890 4af187fce965584d16d3a4ebce802240 453 Pfam PF13660 Domain of unknown function (DUF4147) 14 252 7.5E-73 T 31-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 N186_01890 4af187fce965584d16d3a4ebce802240 453 SUPERFAMILY SSF82544 9 446 1.7E-137 T 31-10-2018 N186_01890 4af187fce965584d16d3a4ebce802240 453 Pfam PF05161 MOFRL family 336 440 6.6E-40 T 31-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 N186_01890 4af187fce965584d16d3a4ebce802240 453 Gene3D G3DSA:3.40.1480.10 280 443 2.4E-155 T 31-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily N186_00770 c62cd34fe8958ec1e58a86c28d16f8a0 283 SUPERFAMILY SSF103481 39 141 6.93E-11 T 31-10-2018 N186_00770 c62cd34fe8958ec1e58a86c28d16f8a0 283 Pfam PF00892 EamA-like transporter family 149 281 1.2E-16 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 N186_00770 c62cd34fe8958ec1e58a86c28d16f8a0 283 Pfam PF00892 EamA-like transporter family 2 137 1.2E-18 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 N186_00770 c62cd34fe8958ec1e58a86c28d16f8a0 283 SUPERFAMILY SSF103481 200 282 6.28E-9 T 31-10-2018 N186_09555 d13646e0eb53281ff2e1bf4631649cde 87 SUPERFAMILY SSF81593 10 72 1.65E-13 T 31-10-2018 N186_09555 d13646e0eb53281ff2e1bf4631649cde 87 SMART SM00748 11 87 4.9E-4 T 31-10-2018 IPR007842 HEPN domain N186_09555 d13646e0eb53281ff2e1bf4631649cde 87 Pfam PF05168 HEPN domain 8 74 3.8E-16 T 31-10-2018 IPR007842 HEPN domain N186_09555 d13646e0eb53281ff2e1bf4631649cde 87 Gene3D G3DSA:1.20.120.330 4 84 4.6E-15 T 31-10-2018 N186_00095 415a73c470da9019225975a93335c653 284 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 7 274 33.025 T 31-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 N186_00095 415a73c470da9019225975a93335c653 284 Pfam PF17284 Spermidine synthase tetramerisation domain 15 59 9.4E-5 T 31-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 N186_00095 415a73c470da9019225975a93335c653 284 SUPERFAMILY SSF53335 7 271 7.75E-72 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_00095 415a73c470da9019225975a93335c653 284 Gene3D G3DSA:3.40.50.150 58 281 8.4E-69 T 31-10-2018 N186_00095 415a73c470da9019225975a93335c653 284 Gene3D G3DSA:2.30.140.10 6 56 3.1E-8 T 31-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 N186_00095 415a73c470da9019225975a93335c653 284 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 83 96 - T 31-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 N186_00095 415a73c470da9019225975a93335c653 284 Pfam PF01564 Spermine/spermidine synthase domain 62 241 9.9E-50 T 31-10-2018 N186_01125 b56200322f621e594b93aa535ac2f32a 450 PIRSF PIRSF006060 1 448 5.0E-70 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 N186_01125 b56200322f621e594b93aa535ac2f32a 450 Pfam PF13520 Amino acid permease 12 423 1.2E-36 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 N186_01125 b56200322f621e594b93aa535ac2f32a 450 Gene3D G3DSA:1.20.1740.10 1 448 7.0E-80 T 31-10-2018 N186_00875 5a40a5ed5b7e08327908c5d07b076c16 427 Gene3D G3DSA:1.20.1250.20 5 415 2.9E-48 T 31-10-2018 N186_00875 5a40a5ed5b7e08327908c5d07b076c16 427 Pfam PF07690 Major Facilitator Superfamily 16 377 3.2E-41 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_00875 5a40a5ed5b7e08327908c5d07b076c16 427 SUPERFAMILY SSF103473 7 416 4.58E-50 T 31-10-2018 IPR036259 MFS transporter superfamily N186_08140 a97b92fa96b9b5be9bea4fd19550381b 155 Gene3D G3DSA:1.20.120.330 45 155 4.4E-20 T 31-10-2018 N186_08140 a97b92fa96b9b5be9bea4fd19550381b 155 Pfam PF05942 Archaeal PaREP1/PaREP8 family 45 147 7.6E-28 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_00555 d5e8d168a84107c3721849806abc5fac 172 Pfam PF06177 QueT transporter 7 166 4.7E-27 T 31-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 N186_00555 d5e8d168a84107c3721849806abc5fac 172 PIRSF PIRSF031501 1 172 3.1E-24 T 31-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 N186_08320 5adb6c4cb7e495f7d3f9a43bafdd9cce 685 SMART SM00642 237 605 1.1E-69 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 N186_08320 5adb6c4cb7e495f7d3f9a43bafdd9cce 685 Pfam PF00128 Alpha amylase, catalytic domain 262 577 7.5E-56 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 N186_08320 5adb6c4cb7e495f7d3f9a43bafdd9cce 685 Gene3D G3DSA:2.60.40.10 126 221 1.0E-5 T 31-10-2018 IPR013783 Immunoglobulin-like fold N186_08320 5adb6c4cb7e495f7d3f9a43bafdd9cce 685 SUPERFAMILY SSF81296 126 229 7.28E-5 T 31-10-2018 IPR014756 Immunoglobulin E-set N186_08320 5adb6c4cb7e495f7d3f9a43bafdd9cce 685 Gene3D G3DSA:2.60.40.10 1 111 3.3E-16 T 31-10-2018 IPR013783 Immunoglobulin-like fold N186_08320 5adb6c4cb7e495f7d3f9a43bafdd9cce 685 SUPERFAMILY SSF51445 228 608 5.8E-86 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily N186_08320 5adb6c4cb7e495f7d3f9a43bafdd9cce 685 Gene3D G3DSA:3.20.20.80 225 610 1.2E-95 T 31-10-2018 N186_05535 2b72ec5dc6a0b6bcb66a76aed49e3aa9 210 Pfam PF01991 ATP synthase (E/31 kDa) subunit 16 207 4.6E-13 T 31-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_05535 2b72ec5dc6a0b6bcb66a76aed49e3aa9 210 SUPERFAMILY SSF160527 91 207 1.22E-12 T 31-10-2018 N186_05535 2b72ec5dc6a0b6bcb66a76aed49e3aa9 210 Gene3D G3DSA:3.30.2320.30 86 208 7.1E-15 T 31-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_05535 2b72ec5dc6a0b6bcb66a76aed49e3aa9 210 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 6 209 10.91 T 31-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_06120 a5a48804cd488ccbd81310b47f036371 256 SUPERFAMILY SSF161098 4 252 3.08E-49 T 31-10-2018 IPR035906 MetI-like superfamily N186_06120 a5a48804cd488ccbd81310b47f036371 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 245 5.9E-20 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_06120 a5a48804cd488ccbd81310b47f036371 256 Gene3D G3DSA:1.10.3720.10 3 253 9.2E-46 T 31-10-2018 IPR035906 MetI-like superfamily N186_01200 28f21f80ee827af73c2b8140c6fe4857 302 Pfam PF04556 DpnII restriction endonuclease 19 284 5.2E-76 T 31-10-2018 IPR007637 Restriction endonuclease, type II, DpmII-like GO:0003677|GO:0009036|GO:0009307 N186_01200 28f21f80ee827af73c2b8140c6fe4857 302 PIRSF PIRSF016080 13 291 5.5E-59 T 31-10-2018 IPR021191 Restriction endonuclease, type II, DpmII GO:0003677|GO:0009036|GO:0009307 N186_01200 28f21f80ee827af73c2b8140c6fe4857 302 SUPERFAMILY SSF52980 69 178 6.97E-6 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_07630 7b5bb21fc3434ed8c1f408ac335c093c 492 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 43 486 1.1E-64 T 31-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 N186_07630 7b5bb21fc3434ed8c1f408ac335c093c 492 Pfam PF00939 Sodium:sulfate symporter transmembrane region 43 484 7.0E-50 T 31-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 N186_06685 fa97606b43df401e51fe18e8756d1a6e 370 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 143 255 2.8E-7 T 31-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 N186_06685 fa97606b43df401e51fe18e8756d1a6e 370 SUPERFAMILY SSF51735 2 158 1.31E-35 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_06685 fa97606b43df401e51fe18e8756d1a6e 370 Gene3D G3DSA:3.40.50.720 1 138 8.2E-28 T 31-10-2018 N186_06685 fa97606b43df401e51fe18e8756d1a6e 370 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 128 6.8E-20 T 31-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 N186_06685 fa97606b43df401e51fe18e8756d1a6e 370 SUPERFAMILY SSF55347 136 303 2.78E-31 T 31-10-2018 N186_06685 fa97606b43df401e51fe18e8756d1a6e 370 Gene3D G3DSA:3.30.360.10 139 370 5.6E-51 T 31-10-2018 N186_08585 83a3f254afe83bc659a75439a6243a94 299 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 276 2.9E-68 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme N186_08585 83a3f254afe83bc659a75439a6243a94 299 SUPERFAMILY SSF53686 4 296 1.18E-81 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme N186_08585 83a3f254afe83bc659a75439a6243a94 299 Gene3D G3DSA:3.40.50.1100 12 292 1.7E-88 T 31-10-2018 N186_08585 83a3f254afe83bc659a75439a6243a94 299 Gene3D G3DSA:3.40.50.1100 39 150 1.7E-88 T 31-10-2018 N186_00820 74e24fcfca61cf0fd22dce4f0677f8f8 104 SUPERFAMILY SSF88723 29 89 1.01E-8 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_00820 74e24fcfca61cf0fd22dce4f0677f8f8 104 Gene3D G3DSA:3.40.50.1010 29 102 2.2E-9 T 31-10-2018 N186_07865 c91e781b04734b9926090df061df6772 278 Gene3D G3DSA:1.10.357.140 18 165 1.3E-12 T 31-10-2018 N186_07865 c91e781b04734b9926090df061df6772 278 Pfam PF01040 UbiA prenyltransferase family 26 261 2.5E-41 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 N186_01860 26d313b08bac2766f504bc77f16343dc 168 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 160 9.0E-31 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 N186_01860 26d313b08bac2766f504bc77f16343dc 168 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 162 1.4E-31 T 31-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 N186_01860 26d313b08bac2766f504bc77f16343dc 168 SUPERFAMILY SSF56300 3 159 2.58E-31 T 31-10-2018 N186_01860 26d313b08bac2766f504bc77f16343dc 168 Gene3D G3DSA:3.60.21.10 3 167 2.1E-41 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_08025 0a208cd068b563f01dc662b84eaae876 77 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 10 70 3.0E-20 T 31-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 N186_08025 0a208cd068b563f01dc662b84eaae876 77 SUPERFAMILY SSF51735 10 74 1.42E-18 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_08025 0a208cd068b563f01dc662b84eaae876 77 Gene3D G3DSA:3.40.50.720 2 76 8.8E-25 T 31-10-2018 N186_06605 449edba076faed362796c70ef815c136 401 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 135 401 1.5E-90 T 31-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06605 449edba076faed362796c70ef815c136 401 Gene3D G3DSA:1.10.645.20 19 401 6.0E-128 T 31-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06605 449edba076faed362796c70ef815c136 401 SUPERFAMILY SSF56762 32 401 9.55E-105 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_08755 43f1c113cfb5127c2ab112d819483f51 161 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 29 158 6.2E-17 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 N186_08755 43f1c113cfb5127c2ab112d819483f51 161 Pfam PF01750 Hydrogenase maturation protease 68 155 1.6E-6 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 N186_08755 43f1c113cfb5127c2ab112d819483f51 161 SUPERFAMILY SSF53163 25 160 1.2E-17 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily N186_08755 43f1c113cfb5127c2ab112d819483f51 161 Gene3D G3DSA:3.40.50.1450 21 161 4.0E-27 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily N186_04650 c6b466db66c9e5d487eb8af0612a9f9a 148 Pfam PF01877 RNA binding 3 116 1.6E-15 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 N186_04650 c6b466db66c9e5d487eb8af0612a9f9a 148 SUPERFAMILY SSF55282 3 143 2.62E-36 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04650 c6b466db66c9e5d487eb8af0612a9f9a 148 Hamap MF_01112 UPF0201 protein . 1 138 25.43 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 N186_04650 c6b466db66c9e5d487eb8af0612a9f9a 148 Gene3D G3DSA:3.30.1440.10 2 140 4.0E-39 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_08680 ac670638fbba0c0a989885aa4f60ff93 55 SUPERFAMILY SSF81301 7 44 7.94E-8 T 31-10-2018 N186_08680 ac670638fbba0c0a989885aa4f60ff93 55 Gene3D G3DSA:3.30.460.10 3 45 1.3E-7 T 31-10-2018 N186_07185 294ef7180ee353936cf319ac9c123767 355 Gene3D G3DSA:3.40.50.2300 67 315 4.7E-73 T 31-10-2018 N186_07185 294ef7180ee353936cf319ac9c123767 355 SUPERFAMILY SSF53822 66 340 1.05E-51 T 31-10-2018 IPR028082 Periplasmic binding protein-like I N186_07185 294ef7180ee353936cf319ac9c123767 355 Gene3D G3DSA:3.40.50.2300 171 306 4.7E-73 T 31-10-2018 N186_07185 294ef7180ee353936cf319ac9c123767 355 Pfam PF13407 Periplasmic binding protein domain 70 321 6.8E-44 T 31-10-2018 IPR025997 Periplasmic binding protein N186_05890 02a3b8f54c12d72da5268971cf9a2200 101 SUPERFAMILY SSF117916 3 100 4.97E-32 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily N186_05890 02a3b8f54c12d72da5268971cf9a2200 101 Gene3D G3DSA:3.30.300.130 2 101 1.1E-38 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily N186_05890 02a3b8f54c12d72da5268971cf9a2200 101 Pfam PF01883 Iron-sulfur cluster assembly protein 7 79 9.6E-22 T 31-10-2018 IPR002744 MIP18 family-like N186_05640 05f035ec6bb0109687291c5e32fbb4bd 303 Gene3D G3DSA:3.40.50.10310 10 284 5.9E-52 T 31-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 N186_05640 05f035ec6bb0109687291c5e32fbb4bd 303 Pfam PF02633 Creatinine amidohydrolase 24 279 2.2E-45 T 31-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 N186_05640 05f035ec6bb0109687291c5e32fbb4bd 303 SUPERFAMILY SSF102215 20 283 1.7E-49 T 31-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 N186_07195 f771bb58d32e1b70ea09fc9805b11a40 253 Gene3D G3DSA:3.40.50.300 2 246 2.0E-59 T 31-10-2018 N186_07195 f771bb58d32e1b70ea09fc9805b11a40 253 SMART SM00382 31 234 1.1E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_07195 f771bb58d32e1b70ea09fc9805b11a40 253 Pfam PF00005 ABC transporter 22 177 1.8E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_07195 f771bb58d32e1b70ea09fc9805b11a40 253 SUPERFAMILY SSF52540 5 236 1.61E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07060 43af766d2359f64171ce4ad4267fd10e 447 Gene3D G3DSA:3.40.1710.10 42 196 6.8E-12 T 31-10-2018 N186_07060 43af766d2359f64171ce4ad4267fd10e 447 Pfam PF12698 ABC-2 family transporter protein 23 410 3.0E-30 T 31-10-2018 N186_01445 cf4378258fbc90628a509d1023ae511b 191 SUPERFAMILY SSF52499 3 180 1.3E-58 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 N186_01445 cf4378258fbc90628a509d1023ae511b 191 Gene3D G3DSA:3.40.50.850 2 190 4.5E-56 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 N186_01445 cf4378258fbc90628a509d1023ae511b 191 Pfam PF00857 Isochorismatase family 5 171 6.1E-49 T 31-10-2018 IPR000868 Isochorismatase-like GO:0003824 N186_01445 cf4378258fbc90628a509d1023ae511b 191 PRINTS PR01398 Isochorismatase signature 35 52 5.3E-8 T 31-10-2018 IPR016291 Isochorismatase GO:0008908 N186_01445 cf4378258fbc90628a509d1023ae511b 191 PRINTS PR01398 Isochorismatase signature 155 172 5.3E-8 T 31-10-2018 IPR016291 Isochorismatase GO:0008908 N186_01445 cf4378258fbc90628a509d1023ae511b 191 PRINTS PR01398 Isochorismatase signature 81 103 5.3E-8 T 31-10-2018 IPR016291 Isochorismatase GO:0008908 N186_08210 52676089ba08c7422dc379e521bc134a 128 SUPERFAMILY SSF53146 1 123 8.63E-25 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily N186_08210 52676089ba08c7422dc379e521bc134a 128 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 18 92 6.8E-16 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis N186_08210 52676089ba08c7422dc379e521bc134a 128 Gene3D G3DSA:3.30.420.130 1 127 2.0E-26 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily N186_01940 e5e0c6d423ea3b85820d145bf589065b 213 Pfam PF01066 CDP-alcohol phosphatidyltransferase 40 104 3.8E-15 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 N186_01940 e5e0c6d423ea3b85820d145bf589065b 213 Gene3D G3DSA:1.20.120.1760 20 210 4.8E-48 T 31-10-2018 N186_01940 e5e0c6d423ea3b85820d145bf589065b 213 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 82 104 - T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 N186_02260 a0be1bc574bec17ca8af4ba7b2f4acbc 145 Hamap MF_01222 Protein archease. 5 145 32.677 T 31-10-2018 IPR022952 Archease, archaea N186_02260 a0be1bc574bec17ca8af4ba7b2f4acbc 145 Pfam PF01951 Archease protein family (MTH1598/TM1083) 7 145 6.6E-41 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 N186_02260 a0be1bc574bec17ca8af4ba7b2f4acbc 145 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 12 145 8.0E-27 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 N186_02260 a0be1bc574bec17ca8af4ba7b2f4acbc 145 SUPERFAMILY SSF69819 6 145 1.44E-41 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 N186_02260 a0be1bc574bec17ca8af4ba7b2f4acbc 145 Gene3D G3DSA:3.55.10.10 5 145 6.4E-42 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 N186_02885 39bae56ab1a843283624baecdfb24240 314 SUPERFAMILY SSF90257 5 110 9.68E-6 T 31-10-2018 N186_02885 39bae56ab1a843283624baecdfb24240 314 Pfam PF15960 Domain of unknown function (DUF4763) 8 103 1.0E-6 T 31-10-2018 IPR031883 Protein of unknown function DUF4763 N186_03875 e8e5d565e225d7e7a0b5e50e67dc82d8 90 Pfam PF01780 Ribosomal L37ae protein family 4 81 2.0E-31 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03875 e8e5d565e225d7e7a0b5e50e67dc82d8 90 SUPERFAMILY SSF57829 11 80 2.2E-25 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 N186_03875 e8e5d565e225d7e7a0b5e50e67dc82d8 90 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 4 73 24.113 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_03875 e8e5d565e225d7e7a0b5e50e67dc82d8 90 Gene3D G3DSA:2.20.25.30 1 89 7.4E-30 T 31-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 N186_07680 b15fa45bde5d97ba1c43e970deca1ef6 116 SUPERFAMILY SSF88659 48 93 3.92E-5 T 31-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like N186_07680 b15fa45bde5d97ba1c43e970deca1ef6 116 Pfam PF02001 Protein of unknown function DUF134 39 102 7.0E-13 T 31-10-2018 IPR002852 Uncharacterised protein family UPF0251 N186_07835 7074d5b3164a4f864ccd680f087ceb85 73 Gene3D G3DSA:3.30.920.30 2 72 1.3E-24 T 31-10-2018 IPR038570 HicA superfamily N186_07835 7074d5b3164a4f864ccd680f087ceb85 73 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 9 64 6.2E-17 T 31-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 N186_07835 7074d5b3164a4f864ccd680f087ceb85 73 SUPERFAMILY SSF54786 4 72 1.1E-18 T 31-10-2018 N186_07740 1eba28cf09dd47521e0ee1e957cb58a7 208 Pfam PF12705 PD-(D/E)XK nuclease superfamily 70 203 7.2E-5 T 31-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type N186_07740 1eba28cf09dd47521e0ee1e957cb58a7 208 Gene3D G3DSA:3.90.320.10 4 207 2.9E-61 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal N186_05105 91e4192485b3d19ac83d7512668832a6 164 Pfam PF01927 Mut7-C RNAse domain 5 150 7.9E-37 T 31-10-2018 IPR002782 Mut7-C RNAse domain N186_04920 58922fea2b665f41f8704e1672184edc 288 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 N186_04920 58922fea2b665f41f8704e1672184edc 288 SUPERFAMILY SSF52540 7 235 4.35E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04920 58922fea2b665f41f8704e1672184edc 288 Gene3D G3DSA:3.40.50.300 8 277 9.1E-67 T 31-10-2018 N186_04920 58922fea2b665f41f8704e1672184edc 288 SMART SM00382 34 219 2.9E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04920 58922fea2b665f41f8704e1672184edc 288 Pfam PF00005 ABC transporter 26 171 8.5E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 N186_02695 f51185b783bcc280bcdc037cc2031476 945 Pfam PF01496 V-type ATPase 116kDa subunit family 837 933 4.3E-8 T 31-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_02695 f51185b783bcc280bcdc037cc2031476 945 Pfam PF01496 V-type ATPase 116kDa subunit family 505 720 2.9E-16 T 31-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_00625 07be8b7c25e31ebb212e19cab989740b 718 SUPERFAMILY SSF56300 146 372 1.36E-34 T 31-10-2018 N186_00625 07be8b7c25e31ebb212e19cab989740b 718 Pfam PF00149 Calcineurin-like phosphoesterase 148 354 7.9E-16 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 N186_00625 07be8b7c25e31ebb212e19cab989740b 718 Gene3D G3DSA:3.60.21.10 135 379 3.4E-21 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like N186_04495 1ef9418b843ed2eed9ee4a4acc542382 118 Pfam PF04434 SWIM zinc finger 51 78 7.0E-4 T 31-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 N186_05095 e8fab2b2e3448eebbd832320b2f1b7b0 611 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 80 215 1.6E-13 T 31-10-2018 N186_05095 e8fab2b2e3448eebbd832320b2f1b7b0 611 Gene3D G3DSA:2.30.310.10 76 151 4.0E-9 T 31-10-2018 N186_05095 e8fab2b2e3448eebbd832320b2f1b7b0 611 Pfam PF05670 Domain of unknown function (DUF814) 414 513 2.5E-26 T 31-10-2018 IPR008532 Domain of unknown function DUF814 N186_07180 f8407c7782d4324ff7af0d9afd81b4db 364 SUPERFAMILY SSF101960 75 339 3.01E-36 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily N186_07180 f8407c7782d4324ff7af0d9afd81b4db 364 Pfam PF01458 Uncharacterized protein family (UPF0051) 112 330 1.2E-30 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 N186_00775 7051114ce78b3141921c6ee66ee1bba0 94 SUPERFAMILY SSF55008 3 56 7.46E-5 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 N186_01070 817ee886165c8c7dc363b195c5e70fc6 442 SUPERFAMILY SSF111283 3 442 1.16E-78 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 N186_01070 817ee886165c8c7dc363b195c5e70fc6 442 Pfam PF01523 Putative modulator of DNA gyrase 24 312 9.5E-44 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 N186_01070 817ee886165c8c7dc363b195c5e70fc6 442 Gene3D G3DSA:3.30.2290.10 1 218 2.0E-26 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal N186_01465 12243b90b5fbbea1a74dd0e74b261a74 233 Gene3D G3DSA:3.30.470.20 22 229 3.8E-65 T 31-10-2018 N186_01465 12243b90b5fbbea1a74dd0e74b261a74 233 Pfam PF13549 ATP-grasp domain 13 231 5.2E-62 T 31-10-2018 N186_01465 12243b90b5fbbea1a74dd0e74b261a74 233 SUPERFAMILY SSF56059 23 232 3.34E-34 T 31-10-2018 N186_01465 12243b90b5fbbea1a74dd0e74b261a74 233 Gene3D G3DSA:3.30.1490.20 39 115 3.8E-65 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 N186_04435 f21989d746d9c714fdaf9cab6f594b68 433 SMART SM00729 142 361 1.5E-46 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 N186_04435 f21989d746d9c714fdaf9cab6f594b68 433 Gene3D G3DSA:3.80.30.20 141 375 5.8E-65 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe N186_04435 f21989d746d9c714fdaf9cab6f594b68 433 Pfam PF04055 Radical SAM superfamily 146 320 3.2E-25 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_04435 f21989d746d9c714fdaf9cab6f594b68 433 SUPERFAMILY SSF102114 136 371 2.09E-48 T 31-10-2018 N186_04435 f21989d746d9c714fdaf9cab6f594b68 433 Pfam PF01938 TRAM domain 372 431 4.0E-12 T 31-10-2018 IPR002792 TRAM domain N186_04435 f21989d746d9c714fdaf9cab6f594b68 433 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 8 429 2.3E-117 T 31-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 N186_04435 f21989d746d9c714fdaf9cab6f594b68 433 Pfam PF00919 Uncharacterized protein family UPF0004 8 104 2.7E-24 T 31-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 N186_04435 f21989d746d9c714fdaf9cab6f594b68 433 Gene3D G3DSA:3.40.50.12160 7 134 1.2E-27 T 31-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily N186_04435 f21989d746d9c714fdaf9cab6f594b68 433 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 8 432 1.2E-112 T 31-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 N186_03750 e27944bd4fdaa76e4805b76d8c0c2e1a 374 Gene3D G3DSA:3.40.50.450 190 371 3.0E-10 T 31-10-2018 N186_03750 e27944bd4fdaa76e4805b76d8c0c2e1a 374 SUPERFAMILY SSF52309 220 338 2.17E-6 T 31-10-2018 N186_03750 e27944bd4fdaa76e4805b76d8c0c2e1a 374 Gene3D G3DSA:3.40.50.300 5 189 1.6E-18 T 31-10-2018 N186_09545 3edf393ec65d27aee9a96295ccda40a4 74 Pfam PF01909 Nucleotidyltransferase domain 1 46 3.8E-6 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_09545 3edf393ec65d27aee9a96295ccda40a4 74 SUPERFAMILY SSF81301 1 66 7.91E-12 T 31-10-2018 N186_09545 3edf393ec65d27aee9a96295ccda40a4 74 Gene3D G3DSA:3.30.460.10 1 73 1.2E-12 T 31-10-2018 N186_01720 dcf0e628642f3e9710e149bd00787b64 383 Gene3D G3DSA:3.90.550.10 2 226 2.3E-34 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_01720 dcf0e628642f3e9710e149bd00787b64 383 Pfam PF13641 Glycosyltransferase like family 2 18 232 3.3E-26 T 31-10-2018 N186_01720 dcf0e628642f3e9710e149bd00787b64 383 SUPERFAMILY SSF53448 17 246 7.79E-42 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_04365 c7df9cc33f7f5dfec2d2108e0d0c007d 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 318 9.1E-48 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 N186_07140 fef2274815a4164ebc95eed9e5404026 248 SUPERFAMILY SSF50182 93 159 7.85E-15 T 31-10-2018 IPR010920 LSM domain superfamily N186_07140 fef2274815a4164ebc95eed9e5404026 248 Gene3D G3DSA:2.30.30.60 109 157 3.4E-11 T 31-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily N186_07140 fef2274815a4164ebc95eed9e5404026 248 Pfam PF00924 Mechanosensitive ion channel 56 246 5.5E-29 T 31-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 N186_08640 3fe2597d899edb6e6f65af336953543d 172 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 51 160 3.9E-7 T 31-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase N186_04000 e0fc44033f466abb2fe829d758a0525d 108 Gene3D G3DSA:1.10.10.10 13 107 2.8E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04000 e0fc44033f466abb2fe829d758a0525d 108 SUPERFAMILY SSF46785 19 105 4.44E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_04000 e0fc44033f466abb2fe829d758a0525d 108 Pfam PF13601 Winged helix DNA-binding domain 23 100 5.3E-12 T 31-10-2018 IPR027395 Winged helix DNA-binding domain N186_09650 58682d75801abb2d7c90b90bf9761332 409 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 381 1.9E-29 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 N186_03135 56d2d92567afb6e5537725f8bb5fed61 116 Pfam PF00085 Thioredoxin 19 101 1.9E-19 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 N186_03135 56d2d92567afb6e5537725f8bb5fed61 116 PRINTS PR00421 Thioredoxin family signature 34 43 8.8E-5 T 31-10-2018 N186_03135 56d2d92567afb6e5537725f8bb5fed61 116 PRINTS PR00421 Thioredoxin family signature 26 34 8.8E-5 T 31-10-2018 N186_03135 56d2d92567afb6e5537725f8bb5fed61 116 PRINTS PR00421 Thioredoxin family signature 76 87 8.8E-5 T 31-10-2018 N186_03135 56d2d92567afb6e5537725f8bb5fed61 116 ProSitePatterns PS00194 Thioredoxin family active site. 27 45 - T 31-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 N186_03135 56d2d92567afb6e5537725f8bb5fed61 116 Gene3D G3DSA:3.40.30.10 7 115 2.7E-25 T 31-10-2018 N186_03135 56d2d92567afb6e5537725f8bb5fed61 116 SUPERFAMILY SSF52833 7 99 2.5E-27 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_02880 71ee59481dce5f7b1a4ffd9cc8681ab6 230 SUPERFAMILY SSF51366 36 226 1.59E-22 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 N186_02880 71ee59481dce5f7b1a4ffd9cc8681ab6 230 Gene3D G3DSA:3.20.20.70 5 229 2.6E-49 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_02880 71ee59481dce5f7b1a4ffd9cc8681ab6 230 SMART SM00934 6 229 6.9E-25 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_02880 71ee59481dce5f7b1a4ffd9cc8681ab6 230 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 222 7.3E-10 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 N186_05230 d8eeb74bfff01f3a44449eabba8c7710 154 SUPERFAMILY SSF46785 8 112 2.89E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_05230 d8eeb74bfff01f3a44449eabba8c7710 154 Gene3D G3DSA:1.10.10.10 5 83 7.7E-12 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_05230 d8eeb74bfff01f3a44449eabba8c7710 154 Pfam PF08221 RNA polymerase III subunit RPC82 helix-turn-helix domain 13 73 6.7E-7 T 31-10-2018 IPR013197 RNA polymerase III subunit RPC82-related, helix-turn-helix Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 N186_05270 6b0bcf55ed34d521b80ea7d73a52cd37 202 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 197 1.1E-63 T 31-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 N186_05270 6b0bcf55ed34d521b80ea7d73a52cd37 202 Gene3D G3DSA:1.10.1760.20 1 198 1.2E-66 T 31-10-2018 N186_07225 f5a0ea8e3de18573b20d82b724b88cef 278 SUPERFAMILY SSF51735 5 140 4.38E-15 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_07225 f5a0ea8e3de18573b20d82b724b88cef 278 Gene3D G3DSA:3.40.50.720 1 151 2.6E-10 T 31-10-2018 N186_07225 f5a0ea8e3de18573b20d82b724b88cef 278 SUPERFAMILY SSF48179 156 244 3.4E-6 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 N186_00960 626199879153ed290865a7e48ef77b0d 237 SUPERFAMILY SSF56784 5 229 3.4E-33 T 31-10-2018 IPR036412 HAD-like superfamily N186_00960 626199879153ed290865a7e48ef77b0d 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 1.3E-5 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_00960 626199879153ed290865a7e48ef77b0d 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 191 204 1.3E-5 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_00960 626199879153ed290865a7e48ef77b0d 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 1.3E-5 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_00960 626199879153ed290865a7e48ef77b0d 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 1.3E-5 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_00960 626199879153ed290865a7e48ef77b0d 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 91 202 3.0E-19 T 31-10-2018 N186_00960 626199879153ed290865a7e48ef77b0d 237 Gene3D G3DSA:3.40.50.1000 7 223 8.0E-36 T 31-10-2018 IPR023214 HAD superfamily N186_00960 626199879153ed290865a7e48ef77b0d 237 Gene3D G3DSA:1.20.120.710 18 100 8.0E-36 T 31-10-2018 N186_00960 626199879153ed290865a7e48ef77b0d 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 117 196 9.4E-8 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 N186_08985 9dceab97520e16dc954bf6347b72678a 158 Pfam PF13620 Carboxypeptidase regulatory-like domain 30 93 7.4E-15 T 31-10-2018 N186_08985 9dceab97520e16dc954bf6347b72678a 158 SUPERFAMILY SSF49464 29 97 3.18E-14 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily N186_08985 9dceab97520e16dc954bf6347b72678a 158 Gene3D G3DSA:2.60.40.1120 27 108 4.7E-11 T 31-10-2018 N186_08725 043c2ddd3e60af29830415c09fe4ba6e 89 Pfam PF01998 Protein of unknown function DUF131 34 76 1.4E-15 T 31-10-2018 IPR002849 Protein of unknown function DUF131 N186_01270 44ad2f2a6bbd5b2f1ac795d09b1b12ce 325 Gene3D G3DSA:3.40.225.10 137 320 2.4E-38 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily N186_01270 44ad2f2a6bbd5b2f1ac795d09b1b12ce 325 SUPERFAMILY SSF53639 141 306 2.79E-36 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily N186_01270 44ad2f2a6bbd5b2f1ac795d09b1b12ce 325 SUPERFAMILY SSF47413 22 60 8.13E-6 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 N186_01270 44ad2f2a6bbd5b2f1ac795d09b1b12ce 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 40 65 6.8E-5 T 31-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 N186_01270 44ad2f2a6bbd5b2f1ac795d09b1b12ce 325 Pfam PF10120 Thiamine-phosphate synthase 147 305 4.9E-40 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 N186_00290 2bbb4fcb746ad682b3bf4f0fce90449f 243 Pfam PF04055 Radical SAM superfamily 50 211 9.5E-20 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_00290 2bbb4fcb746ad682b3bf4f0fce90449f 243 Gene3D G3DSA:3.20.20.70 50 241 3.4E-27 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_00290 2bbb4fcb746ad682b3bf4f0fce90449f 243 Pfam PF13353 4Fe-4S single cluster domain 42 157 1.2E-5 T 31-10-2018 N186_00290 2bbb4fcb746ad682b3bf4f0fce90449f 243 SUPERFAMILY SSF102114 51 217 1.7E-25 T 31-10-2018 N186_08520 4da8f8be4900c606996950a9be6bbb94 185 Pfam PF02634 FdhD/NarQ family 42 183 3.0E-43 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 N186_08520 4da8f8be4900c606996950a9be6bbb94 185 SUPERFAMILY SSF53927 1 184 9.02E-45 T 31-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 N186_08520 4da8f8be4900c606996950a9be6bbb94 185 Gene3D G3DSA:3.40.140.10 37 185 1.8E-40 T 31-10-2018 N186_03720 22b20639234b3a17abdd7e76efcda78a 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 10 26 6.8E-11 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03720 22b20639234b3a17abdd7e76efcda78a 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 226 239 6.8E-11 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03720 22b20639234b3a17abdd7e76efcda78a 410 Gene3D G3DSA:3.90.120.10 266 387 6.7E-41 T 31-10-2018 N186_03720 22b20639234b3a17abdd7e76efcda78a 410 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 83 95 - T 31-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 N186_03720 22b20639234b3a17abdd7e76efcda78a 410 SUPERFAMILY SSF53335 9 398 5.88E-87 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_03720 22b20639234b3a17abdd7e76efcda78a 410 Gene3D G3DSA:3.40.50.150 169 265 1.4E-15 T 31-10-2018 N186_03720 22b20639234b3a17abdd7e76efcda78a 410 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 12 135 2.8E-32 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03720 22b20639234b3a17abdd7e76efcda78a 410 Gene3D G3DSA:3.40.50.150 7 168 5.6E-42 T 31-10-2018 N186_03720 22b20639234b3a17abdd7e76efcda78a 410 Pfam PF00145 C-5 cytosine-specific DNA methylase 195 398 1.4E-32 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_03720 22b20639234b3a17abdd7e76efcda78a 410 Pfam PF00145 C-5 cytosine-specific DNA methylase 10 136 8.5E-37 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 N186_09350 f195e34e720fab9db83999bab4cc1827 453 SUPERFAMILY SSF52540 1 227 7.68E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09350 f195e34e720fab9db83999bab4cc1827 453 Gene3D G3DSA:3.40.50.300 1 231 4.8E-22 T 31-10-2018 N186_09350 f195e34e720fab9db83999bab4cc1827 453 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 8 221 1.4E-10 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain N186_05500 9aa5a4d7005a354dbcf2fbc018d0a8b4 935 Gene3D G3DSA:2.60.40.1120 388 464 2.7E-6 T 31-10-2018 N186_05500 9aa5a4d7005a354dbcf2fbc018d0a8b4 935 SUPERFAMILY SSF49464 389 454 3.1E-6 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily N186_05500 9aa5a4d7005a354dbcf2fbc018d0a8b4 935 Pfam PF08308 PEGA domain 399 453 3.8E-7 T 31-10-2018 IPR013229 PEGA N186_05500 9aa5a4d7005a354dbcf2fbc018d0a8b4 935 SUPERFAMILY SSF82171 35 373 8.24E-9 T 31-10-2018 N186_05500 9aa5a4d7005a354dbcf2fbc018d0a8b4 935 SUPERFAMILY SSF52833 541 637 5.47E-9 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_05500 9aa5a4d7005a354dbcf2fbc018d0a8b4 935 Gene3D G3DSA:3.40.30.10 537 637 3.5E-7 T 31-10-2018 N186_02995 e47952b4cf30275680c6dcddee9c8dbe 325 Pfam PF01935 Domain of unknown function DUF87 25 67 1.1E-12 T 31-10-2018 IPR002789 Helicase HerA, central domain N186_02995 e47952b4cf30275680c6dcddee9c8dbe 325 Gene3D G3DSA:3.40.50.300 7 128 2.1E-12 T 31-10-2018 N186_02995 e47952b4cf30275680c6dcddee9c8dbe 325 Gene3D G3DSA:3.40.50.300 155 324 1.7E-10 T 31-10-2018 N186_02995 e47952b4cf30275680c6dcddee9c8dbe 325 SUPERFAMILY SSF52540 21 260 2.81E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09495 fa281c668195c041e07ab8664bf5b4b9 223 Gene3D G3DSA:1.20.5.1230 2 148 1.3E-5 T 31-10-2018 N186_04460 7b40cb71e1440851872fc383f6d0065c 319 SUPERFAMILY SSF56281 12 312 1.76E-38 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_04460 7b40cb71e1440851872fc383f6d0065c 319 SMART SM00849 7 156 5.3E-11 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_04460 7b40cb71e1440851872fc383f6d0065c 319 Pfam PF13483 Beta-lactamase superfamily domain 11 117 7.2E-9 T 31-10-2018 N186_04460 7b40cb71e1440851872fc383f6d0065c 319 Gene3D G3DSA:3.60.15.10 3 209 3.0E-28 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_02710 67ca900acd46caba26fecc53dcacbb57 200 Pfam PF01813 ATP synthase subunit D 16 196 1.0E-30 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_06385 bd71b37c1cfb270927495ba629a0639a 276 Gene3D G3DSA:3.30.460.10 1 107 1.5E-5 T 31-10-2018 N186_06385 bd71b37c1cfb270927495ba629a0639a 276 SUPERFAMILY SSF81301 3 106 7.94E-9 T 31-10-2018 N186_01085 83a7b3d4d3f27efaa1b6628e52c0e336 146 Gene3D G3DSA:1.20.120.580 8 146 9.0E-14 T 31-10-2018 IPR037038 Bsu32300-like superfamily N186_01085 83a7b3d4d3f27efaa1b6628e52c0e336 146 SUPERFAMILY SSF81593 71 136 2.59E-7 T 31-10-2018 N186_01085 83a7b3d4d3f27efaa1b6628e52c0e336 146 Pfam PF01934 Protein of unknown function DUF86 26 137 5.0E-20 T 31-10-2018 IPR008201 Protein of unknown function DUF86 N186_00035 ebb22ed9adc8e71dfb2213f9e1bbebc7 412 Hamap MF_02096 DNA repair protein. 1 404 35.647 T 31-10-2018 IPR033167 Archaeal Nre GO:0006281 N186_00035 ebb22ed9adc8e71dfb2213f9e1bbebc7 412 Pfam PF04895 Archaeal Nre, C-terminal 295 404 6.5E-36 T 31-10-2018 IPR006979 Archaeal Nre, C-terminal N186_00035 ebb22ed9adc8e71dfb2213f9e1bbebc7 412 Pfam PF04894 Archaeal Nre, N-terminal 18 283 3.8E-95 T 31-10-2018 IPR006978 Archaeal Nre, N-terminal N186_02460 a61fc75e3ba8d9cd309f3f936de8f0fe 93 Gene3D G3DSA:1.10.1220.10 2 49 1.5E-5 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 N186_02460 a61fc75e3ba8d9cd309f3f936de8f0fe 93 SUPERFAMILY SSF47598 2 43 4.67E-6 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 N186_02460 a61fc75e3ba8d9cd309f3f936de8f0fe 93 Pfam PF16777 Transcriptional regulator, RHH-like, CopG 2 44 1.6E-7 T 31-10-2018 IPR031895 RHH transcriptional regulator CopG N186_03560 ae3e350a4611f6f38ee833495d27d172 209 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 120 126 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 N186_03560 ae3e350a4611f6f38ee833495d27d172 209 Gene3D G3DSA:3.40.50.150 1 207 4.6E-49 T 31-10-2018 N186_03560 ae3e350a4611f6f38ee833495d27d172 209 Pfam PF05175 Methyltransferase small domain 48 131 2.5E-10 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 N186_03560 ae3e350a4611f6f38ee833495d27d172 209 SUPERFAMILY SSF53335 3 154 1.91E-26 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_05835 9050016b5853baf87a35501321ada9b4 373 Pfam PF13353 4Fe-4S single cluster domain 155 243 6.4E-6 T 31-10-2018 N186_05835 9050016b5853baf87a35501321ada9b4 373 PIRSF PIRSF004869 67 370 3.7E-67 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted N186_05835 9050016b5853baf87a35501321ada9b4 373 Gene3D G3DSA:3.20.20.70 153 326 4.2E-21 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_05835 9050016b5853baf87a35501321ada9b4 373 SUPERFAMILY SSF102114 159 345 1.44E-20 T 31-10-2018 N186_05835 9050016b5853baf87a35501321ada9b4 373 Pfam PF04055 Radical SAM superfamily 156 304 8.9E-16 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_05820 eb53692a0fa3e4484d00d1fc8495c750 378 SUPERFAMILY SSF52540 5 162 1.35E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_05820 eb53692a0fa3e4484d00d1fc8495c750 378 Pfam PF02562 PhoH-like protein 6 204 7.0E-36 T 31-10-2018 IPR003714 PhoH-like protein GO:0005524 N186_05820 eb53692a0fa3e4484d00d1fc8495c750 378 Gene3D G3DSA:3.40.50.300 3 206 1.7E-30 T 31-10-2018 N186_05820 eb53692a0fa3e4484d00d1fc8495c750 378 Pfam PF00013 KH domain 270 295 2.5E-4 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 N186_05205 2f3b85daf3f86a743fb9df5d56918908 386 SUPERFAMILY SSF53850 56 381 6.86E-79 T 31-10-2018 N186_05205 2f3b85daf3f86a743fb9df5d56918908 386 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 56 380 3.7E-88 T 31-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 N186_05205 2f3b85daf3f86a743fb9df5d56918908 386 PIRSF PIRSF002756 6 384 3.6E-107 T 31-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 N186_05205 2f3b85daf3f86a743fb9df5d56918908 386 Gene3D G3DSA:3.40.190.10 136 324 1.0E-98 T 31-10-2018 N186_05205 2f3b85daf3f86a743fb9df5d56918908 386 Pfam PF12849 PBP superfamily domain 47 355 2.0E-56 T 31-10-2018 IPR024370 PBP domain N186_05205 2f3b85daf3f86a743fb9df5d56918908 386 Gene3D G3DSA:3.40.190.10 60 372 1.0E-98 T 31-10-2018 N186_03985 cdf0e946d097b7f8338c42dd7c0c82d6 140 SUPERFAMILY SSF88723 4 126 5.33E-19 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_03985 cdf0e946d097b7f8338c42dd7c0c82d6 140 Gene3D G3DSA:3.40.50.1010 2 129 1.5E-29 T 31-10-2018 N186_03985 cdf0e946d097b7f8338c42dd7c0c82d6 140 Pfam PF01850 PIN domain 4 124 1.4E-9 T 31-10-2018 IPR002716 PIN domain N186_06390 54d515d6e4576797a24fc808013c01f3 145 Gene3D G3DSA:3.30.428.10 2 144 3.3E-38 T 31-10-2018 IPR036265 HIT-like superfamily N186_06390 54d515d6e4576797a24fc808013c01f3 145 Pfam PF01230 HIT domain 21 114 1.1E-22 T 31-10-2018 IPR001310 Histidine triad (HIT) protein N186_06390 54d515d6e4576797a24fc808013c01f3 145 PRINTS PR00332 Histidine triad family signature 35 53 4.8E-12 T 31-10-2018 IPR001310 Histidine triad (HIT) protein N186_06390 54d515d6e4576797a24fc808013c01f3 145 PRINTS PR00332 Histidine triad family signature 14 30 4.8E-12 T 31-10-2018 IPR001310 Histidine triad (HIT) protein N186_06390 54d515d6e4576797a24fc808013c01f3 145 PRINTS PR00332 Histidine triad family signature 102 112 4.8E-12 T 31-10-2018 IPR001310 Histidine triad (HIT) protein N186_06390 54d515d6e4576797a24fc808013c01f3 145 SUPERFAMILY SSF54197 10 140 1.41E-36 T 31-10-2018 IPR036265 HIT-like superfamily N186_00050 287be753088a4f5266e6c11127ef497c 142 SUPERFAMILY SSF88723 4 112 8.83E-11 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_00050 287be753088a4f5266e6c11127ef497c 142 Gene3D G3DSA:3.40.50.1010 1 121 3.0E-6 T 31-10-2018 N186_00050 287be753088a4f5266e6c11127ef497c 142 Pfam PF01850 PIN domain 23 110 1.9E-8 T 31-10-2018 IPR002716 PIN domain N186_01665 d002faf62272c64b9c68f2b24e1109ab 354 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 147 350 9.0E-31 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_01665 d002faf62272c64b9c68f2b24e1109ab 354 SUPERFAMILY SSF161098 122 333 6.28E-15 T 31-10-2018 IPR035906 MetI-like superfamily N186_01665 d002faf62272c64b9c68f2b24e1109ab 354 Gene3D G3DSA:1.10.3720.10 118 346 1.1E-15 T 31-10-2018 IPR035906 MetI-like superfamily N186_01865 853f04235c97d77406a7c568ec5e309a 116 Pfam PF04434 SWIM zinc finger 68 86 5.6E-4 T 31-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 N186_06625 8736ca7a8c244b265a37e1814cd19815 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 13.529 T 31-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 N186_06625 8736ca7a8c244b265a37e1814cd19815 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 94 2.0E-11 T 31-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like N186_06595 b8c300efef83bae53e7b535d225db831 174 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 54 161 4.4E-22 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06595 b8c300efef83bae53e7b535d225db831 174 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 30 168 1.7E-51 T 31-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 N186_06595 b8c300efef83bae53e7b535d225db831 174 Gene3D G3DSA:3.40.50.12280 13 174 4.5E-57 T 31-10-2018 N186_06595 b8c300efef83bae53e7b535d225db831 174 SUPERFAMILY SSF56770 31 171 4.19E-56 T 31-10-2018 N186_09505 198bc8f2f504a59f69abda43c44f8e7f 353 PIRSF PIRSF026760 2 351 2.0E-114 T 31-10-2018 IPR011669 Uncharacterised conserved protein UCP026760 N186_09505 198bc8f2f504a59f69abda43c44f8e7f 353 Gene3D G3DSA:3.40.50.300 142 346 1.9E-61 T 31-10-2018 N186_09505 198bc8f2f504a59f69abda43c44f8e7f 353 Gene3D G3DSA:3.40.50.720 1 138 1.4E-50 T 31-10-2018 N186_09505 198bc8f2f504a59f69abda43c44f8e7f 353 Pfam PF17396 Domain of unknown function (DUF1611_N) Rossmann-like domain 41 136 1.3E-30 T 31-10-2018 IPR035402 Domain of unknown function DUF1611-N, Rossmann-like domain N186_09505 198bc8f2f504a59f69abda43c44f8e7f 353 SUPERFAMILY SSF52540 3 345 3.66E-94 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_09505 198bc8f2f504a59f69abda43c44f8e7f 353 Pfam PF07755 Domain of unknown function (DUF1611_C) P-loop domain 144 341 4.3E-62 T 31-10-2018 IPR035086 Domain of unknown function DUF1611, P-loop N186_01490 e78522428aaf6ee0d933a9f4ee7b6988 407 Pfam PF01494 FAD binding domain 151 317 7.5E-9 T 31-10-2018 IPR002938 FAD-binding domain GO:0071949 N186_01490 e78522428aaf6ee0d933a9f4ee7b6988 407 Gene3D G3DSA:3.50.50.60 19 402 5.9E-49 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_01490 e78522428aaf6ee0d933a9f4ee7b6988 407 SUPERFAMILY SSF51905 20 353 5.26E-29 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_01490 e78522428aaf6ee0d933a9f4ee7b6988 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 164 179 7.9E-11 T 31-10-2018 N186_01490 e78522428aaf6ee0d933a9f4ee7b6988 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 7.9E-11 T 31-10-2018 N186_01490 e78522428aaf6ee0d933a9f4ee7b6988 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 26 48 7.9E-11 T 31-10-2018 N186_00245 f51825e9ccfb8bbb5152266e39f541f8 305 SUPERFAMILY SSF46785 239 300 2.77E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_00245 f51825e9ccfb8bbb5152266e39f541f8 305 Pfam PF13412 Winged helix-turn-helix DNA-binding 247 291 5.5E-9 T 31-10-2018 N186_00245 f51825e9ccfb8bbb5152266e39f541f8 305 Gene3D G3DSA:1.10.10.10 243 305 1.3E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_00930 726867276edb577d5c5628d16b9110c5 117 SUPERFAMILY SSF51182 19 106 1.26E-5 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily N186_00930 726867276edb577d5c5628d16b9110c5 117 Gene3D G3DSA:2.60.120.10 4 117 2.2E-13 T 31-10-2018 IPR014710 RmlC-like jelly roll fold N186_07070 44c45a8dd4cbbf8342309b28ec962e0d 199 Pfam PF01914 MarC family integral membrane protein 7 193 9.3E-42 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 N186_07070 44c45a8dd4cbbf8342309b28ec962e0d 199 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 10 190 1.6E-36 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 N186_01580 f8d6d25332746c5ea18e8620f0f2991f 236 SUPERFAMILY SSF117396 3 228 1.83E-61 T 31-10-2018 IPR036520 UPF0759 superfamily N186_01580 f8d6d25332746c5ea18e8620f0f2991f 236 Gene3D G3DSA:3.20.20.410 1 231 3.0E-55 T 31-10-2018 IPR036520 UPF0759 superfamily N186_01580 f8d6d25332746c5ea18e8620f0f2991f 236 Pfam PF01904 Protein of unknown function DUF72 17 216 3.2E-48 T 31-10-2018 IPR002763 Protein of unknown function DUF72 N186_08500 e705c1144772ffe3ad124969a13ddbec 119 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 8 101 4.9E-9 T 31-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system N186_02950 7be7b111128fcef7024d445102ae430b 105 SUPERFAMILY SSF160350 1 96 3.92E-7 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 N186_02950 7be7b111128fcef7024d445102ae430b 105 Gene3D G3DSA:3.30.70.3250 1 98 6.3E-8 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 N186_02195 6fc50418da22753cbc86ea58f723fd7c 162 Gene3D G3DSA:3.30.420.80 10 162 2.4E-51 T 31-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 N186_02195 6fc50418da22753cbc86ea58f723fd7c 162 Pfam PF00411 Ribosomal protein S11 40 158 2.7E-42 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 N186_02195 6fc50418da22753cbc86ea58f723fd7c 162 SUPERFAMILY SSF53137 39 160 7.66E-34 T 31-10-2018 N186_02195 6fc50418da22753cbc86ea58f723fd7c 162 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 20 159 22.096 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 N186_02195 6fc50418da22753cbc86ea58f723fd7c 162 PIRSF PIRSF002131 8 161 3.3E-31 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 N186_02195 6fc50418da22753cbc86ea58f723fd7c 162 ProSitePatterns PS00054 Ribosomal protein S11 signature. 127 149 - T 31-10-2018 IPR018102 Ribosomal S11, conserved site N186_04700 a494c4b777c9f728e53cc9c4ab5896a6 215 SUPERFAMILY SSF74784 14 190 4.45E-28 T 31-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 N186_04700 a494c4b777c9f728e53cc9c4ab5896a6 215 Pfam PF01997 Translin family 25 183 3.2E-9 T 31-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 N186_04700 a494c4b777c9f728e53cc9c4ab5896a6 215 Gene3D G3DSA:1.20.58.2140 8 206 1.1E-63 T 31-10-2018 N186_07635 3a143cf73fcfdded220ddaeed621df50 408 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 31 392 3.8E-101 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 N186_07635 3a143cf73fcfdded220ddaeed621df50 408 Gene3D G3DSA:3.40.50.11750 47 285 3.6E-89 T 31-10-2018 N186_07635 3a143cf73fcfdded220ddaeed621df50 408 Pfam PF01924 Hydrogenase formation hypA family 36 392 1.1E-118 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 N186_07635 3a143cf73fcfdded220ddaeed621df50 408 PIRSF PIRSF005622 22 396 4.2E-116 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 N186_07635 3a143cf73fcfdded220ddaeed621df50 408 Gene3D G3DSA:3.40.50.11740 82 325 3.6E-89 T 31-10-2018 N186_07635 3a143cf73fcfdded220ddaeed621df50 408 Gene3D G3DSA:1.10.10.2140 345 394 6.1E-22 T 31-10-2018 N186_02685 01ffb15b6a70b337d98db3839a07b8db 637 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 29 636 3.7E-127 T 31-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 N186_02685 01ffb15b6a70b337d98db3839a07b8db 637 SUPERFAMILY SSF51998 33 621 6.41E-122 T 31-10-2018 N186_02685 01ffb15b6a70b337d98db3839a07b8db 637 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 30 637 3.5E-149 T 31-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 N186_02685 01ffb15b6a70b337d98db3839a07b8db 637 Gene3D G3DSA:3.20.70.20 38 619 1.2E-72 T 31-10-2018 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 Pfam PF00701 Dihydrodipicolinate synthetase family 4 294 4.2E-69 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 SUPERFAMILY SSF51569 2 299 3.14E-82 T 31-10-2018 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 136 167 - T 31-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 SMART SM01130 4 298 7.0E-99 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 PIRSF PIRSF001365 1 301 6.5E-84 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 1.2E-17 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 1.2E-17 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 1.2E-17 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 1.2E-17 T 31-10-2018 IPR002220 DapA-like GO:0016829 N186_00185 5f2c301e422f69d042ef70fbce904a3a 301 Gene3D G3DSA:3.20.20.70 4 300 8.2E-94 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 Pfam PF00162 Phosphoglycerate kinase 10 393 1.3E-112 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PRINTS PR00477 Phosphoglycerate kinase family signature 203 222 4.6E-58 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PRINTS PR00477 Phosphoglycerate kinase family signature 326 351 4.6E-58 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PRINTS PR00477 Phosphoglycerate kinase family signature 180 202 4.6E-58 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PRINTS PR00477 Phosphoglycerate kinase family signature 359 370 4.6E-58 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PRINTS PR00477 Phosphoglycerate kinase family signature 114 129 4.6E-58 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PRINTS PR00477 Phosphoglycerate kinase family signature 382 399 4.6E-58 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PRINTS PR00477 Phosphoglycerate kinase family signature 149 171 4.6E-58 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PRINTS PR00477 Phosphoglycerate kinase family signature 14 30 4.6E-58 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PRINTS PR00477 Phosphoglycerate kinase family signature 37 59 4.6E-58 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 PIRSF PIRSF000724 3 409 4.8E-132 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 9 406 34.088 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 Gene3D G3DSA:3.40.50.1260 199 396 1.5E-127 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 Gene3D G3DSA:3.40.50.1260 14 402 1.5E-127 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_05385 f9e217e4d45c8573f52d99f7ae53e98b 409 SUPERFAMILY SSF53748 5 406 6.24E-116 T 31-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 N186_02805 7421a2d23b9dacea377ca21ff30d1a45 249 Gene3D G3DSA:3.40.50.10900 14 247 2.4E-44 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily N186_02805 7421a2d23b9dacea377ca21ff30d1a45 249 SUPERFAMILY SSF159659 21 240 7.19E-28 T 31-10-2018 N186_02805 7421a2d23b9dacea377ca21ff30d1a45 249 Pfam PF09754 PAC2 family 25 231 2.1E-32 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 N186_02705 3a1f32ad9473a5eaf13b9761c2d3f775 294 Pfam PF01992 ATP synthase (C/AC39) subunit 8 200 8.2E-7 T 31-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_02705 3a1f32ad9473a5eaf13b9761c2d3f775 294 SUPERFAMILY SSF103486 4 291 9.15E-8 T 31-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 N186_08090 13ac9b2d87c5cf0cc7921658f002e3ce 72 Gene3D G3DSA:3.30.160.250 5 72 4.4E-18 T 31-10-2018 N186_08090 13ac9b2d87c5cf0cc7921658f002e3ce 72 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 7 69 1.6E-10 T 31-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system N186_08090 13ac9b2d87c5cf0cc7921658f002e3ce 72 SUPERFAMILY SSF143100 2 61 6.28E-19 T 31-10-2018 IPR035069 TTHA1013/TTHA0281-like N186_08750 e759104a3742deb3416276b75ed8490e 480 Pfam PF16257 tagaturonate epimerase 129 377 4.6E-26 T 31-10-2018 IPR032586 Tagaturonate epimerase N186_04865 95c0178df7deed3eceddcfda7fe1c5cb 364 Pfam PF07431 Protein of unknown function (DUF1512) 8 363 5.4E-119 T 31-10-2018 IPR009995 Protein of unknown function DUF1512 N186_04865 95c0178df7deed3eceddcfda7fe1c5cb 364 PIRSF PIRSF016495 4 364 5.8E-104 T 31-10-2018 IPR009995 Protein of unknown function DUF1512 N186_07315 023fc37483be9021f93a7f234ab97988 272 Gene3D G3DSA:2.20.28.160 223 269 1.6E-6 T 31-10-2018 N186_07335 09ef532555ec45481d4c70e1df3e079b 265 Pfam PF00795 Carbon-nitrogen hydrolase 3 243 4.0E-32 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 N186_07335 09ef532555ec45481d4c70e1df3e079b 265 Gene3D G3DSA:3.60.110.10 1 265 8.7E-61 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily N186_07335 09ef532555ec45481d4c70e1df3e079b 265 SUPERFAMILY SSF56317 2 261 2.35E-57 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily N186_05710 523d376ad07e24286b5d13dbc0313087 234 Pfam PF04519 Polymer-forming cytoskeletal 20 104 3.4E-8 T 31-10-2018 IPR007607 Bactofilin A/B N186_07455 ae38b6b49f9e92d0a310b96dea9ece06 305 SUPERFAMILY SSF161098 75 291 2.09E-49 T 31-10-2018 IPR035906 MetI-like superfamily N186_07455 ae38b6b49f9e92d0a310b96dea9ece06 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 293 1.4E-15 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_07455 ae38b6b49f9e92d0a310b96dea9ece06 305 Gene3D G3DSA:1.10.3720.10 71 300 6.9E-61 T 31-10-2018 IPR035906 MetI-like superfamily N186_00030 140876fc9017657b725daf122c66a0ef 283 Gene3D G3DSA:3.20.20.70 33 238 4.8E-6 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_00030 140876fc9017657b725daf122c66a0ef 283 SUPERFAMILY SSF102114 33 211 2.22E-6 T 31-10-2018 N186_00030 140876fc9017657b725daf122c66a0ef 283 Pfam PF04055 Radical SAM superfamily 31 202 3.0E-10 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_08000 39b9ecad04a40b16598ff3526e72abfe 354 Pfam PF00535 Glycosyl transferase family 2 20 138 5.8E-23 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 N186_08000 39b9ecad04a40b16598ff3526e72abfe 354 SUPERFAMILY SSF53448 17 294 3.78E-38 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_08000 39b9ecad04a40b16598ff3526e72abfe 354 Gene3D G3DSA:3.90.550.10 3 253 1.2E-38 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_02325 21d2592968d015aa7e6b973197742ec5 103 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 8 93 1.7E-19 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 N186_02325 21d2592968d015aa7e6b973197742ec5 103 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 3 100 26.123 T 31-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_02325 21d2592968d015aa7e6b973197742ec5 103 SUPERFAMILY SSF55315 4 96 8.25E-27 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like N186_02325 21d2592968d015aa7e6b973197742ec5 103 Gene3D G3DSA:3.30.1330.30 2 103 3.3E-35 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like N186_04830 26b5271468fd923835c42abd1bca6d23 198 Pfam PF05239 PRC-barrel domain 16 75 2.7E-5 T 31-10-2018 IPR027275 PRC-barrel domain N186_04830 26b5271468fd923835c42abd1bca6d23 198 SUPERFAMILY SSF50346 15 67 3.53E-5 T 31-10-2018 IPR011033 PRC-barrel-like superfamily N186_08265 e7b58de3a64527f68feac749881e873b 426 Gene3D G3DSA:3.40.50.10640 2 286 3.0E-28 T 31-10-2018 N186_08265 e7b58de3a64527f68feac749881e873b 426 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 119 136 3.9E-6 T 31-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site N186_08265 e7b58de3a64527f68feac749881e873b 426 SUPERFAMILY SSF160980 5 406 1.83E-41 T 31-10-2018 N186_08265 e7b58de3a64527f68feac749881e873b 426 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 5 146 3.5E-7 T 31-10-2018 IPR019016 CRISPR-associated DxTHG protein N186_06230 3a7bfd40eaabedf0e0651010bc42279a 542 Gene3D G3DSA:3.50.30.30 57 194 2.0E-39 T 31-10-2018 N186_06230 3a7bfd40eaabedf0e0651010bc42279a 542 SUPERFAMILY SSF52025 64 187 9.16E-11 T 31-10-2018 N186_06230 3a7bfd40eaabedf0e0651010bc42279a 542 Pfam PF04389 Peptidase family M28 213 376 1.4E-8 T 31-10-2018 IPR007484 Peptidase M28 N186_06230 3a7bfd40eaabedf0e0651010bc42279a 542 Gene3D G3DSA:3.40.630.10 20 375 2.0E-39 T 31-10-2018 N186_06230 3a7bfd40eaabedf0e0651010bc42279a 542 SUPERFAMILY SSF53187 15 384 1.98E-18 T 31-10-2018 N186_06230 3a7bfd40eaabedf0e0651010bc42279a 542 Pfam PF02225 PA domain 95 177 4.6E-5 T 31-10-2018 IPR003137 PA domain N186_07580 52a098eb9324a486754a56832563d74e 340 SUPERFAMILY SSF161098 94 324 4.41E-16 T 31-10-2018 IPR035906 MetI-like superfamily N186_07580 52a098eb9324a486754a56832563d74e 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 340 1.5E-38 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_08035 07824641144f9010c4c43b6cf5a8f213 101 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 97 2.7E-17 T 31-10-2018 IPR023811 Conserved hypothetical protein CHP04076 N186_06720 78e05c0dfefb3cf7a789c041eb28d7d7 106 Gene3D G3DSA:3.40.50.2300 11 98 2.6E-17 T 31-10-2018 N186_06720 78e05c0dfefb3cf7a789c041eb28d7d7 106 SUPERFAMILY SSF52794 11 97 1.41E-14 T 31-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 N186_06720 78e05c0dfefb3cf7a789c041eb28d7d7 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 12 93 3.4E-9 T 31-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 N186_09410 cfd085b3b99333d499ca6d5c156e918e 203 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 197 1.3E-17 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 N186_00480 c67b41188fbfac60ff38fafa5a9fc8e0 290 SUPERFAMILY SSF161098 5 285 7.46E-31 T 31-10-2018 IPR035906 MetI-like superfamily N186_00480 c67b41188fbfac60ff38fafa5a9fc8e0 290 Gene3D G3DSA:1.10.3720.10 7 285 2.9E-29 T 31-10-2018 IPR035906 MetI-like superfamily N186_01825 5730a9deeef583cbe65cec1e5e9c9bf8 189 Gene3D G3DSA:3.40.220.10 2 186 4.8E-60 T 31-10-2018 N186_01825 5730a9deeef583cbe65cec1e5e9c9bf8 189 SMART SM00506 12 143 2.6E-50 T 31-10-2018 IPR002589 Macro domain N186_01825 5730a9deeef583cbe65cec1e5e9c9bf8 189 SUPERFAMILY SSF52949 4 178 1.46E-56 T 31-10-2018 N186_01825 5730a9deeef583cbe65cec1e5e9c9bf8 189 Pfam PF01661 Macro domain 29 143 7.9E-35 T 31-10-2018 IPR002589 Macro domain N186_04520 8ae4918e815d957d76b9ad8db89ec573 284 Gene3D G3DSA:1.10.357.140 14 175 2.2E-18 T 31-10-2018 N186_04520 8ae4918e815d957d76b9ad8db89ec573 284 Pfam PF01040 UbiA prenyltransferase family 40 267 2.1E-36 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 N186_05405 afb3ac3058c754f747b35b9e775489a2 284 Pfam PF00482 Type II secretion system (T2SS), protein F 112 238 7.8E-12 T 31-10-2018 IPR018076 Type II secretion system F domain N186_02090 a124e7e908ad169b4d3944c836048f9d 159 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 9 159 3.1E-49 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 N186_02090 a124e7e908ad169b4d3944c836048f9d 159 Gene3D G3DSA:3.30.1390.20 9 147 6.0E-46 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily N186_02090 a124e7e908ad169b4d3944c836048f9d 159 SUPERFAMILY SSF55129 6 159 4.11E-39 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily N186_02090 a124e7e908ad169b4d3944c836048f9d 159 Gene3D G3DSA:1.10.15.30 64 118 6.0E-46 T 31-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type N186_02090 a124e7e908ad169b4d3944c836048f9d 159 Pfam PF00327 Ribosomal protein L30p/L7e 7 51 9.7E-13 T 31-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain N186_02090 a124e7e908ad169b4d3944c836048f9d 159 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 159 66.515 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 N186_01510 626d87f3d466fa22c5de6ab666928ff4 264 Gene3D G3DSA:3.20.20.140 1 263 2.6E-68 T 31-10-2018 N186_01510 626d87f3d466fa22c5de6ab666928ff4 264 PIRSF PIRSF005902 1 264 2.5E-58 T 31-10-2018 IPR001130 TatD family GO:0016788 N186_01510 626d87f3d466fa22c5de6ab666928ff4 264 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 138 148 - T 31-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 N186_01510 626d87f3d466fa22c5de6ab666928ff4 264 Pfam PF01026 TatD related DNase 2 261 1.2E-58 T 31-10-2018 IPR001130 TatD family GO:0016788 N186_01510 626d87f3d466fa22c5de6ab666928ff4 264 SUPERFAMILY SSF51556 2 262 2.27E-64 T 31-10-2018 IPR032466 Metal-dependent hydrolase N186_00795 a1955bcf96b9555159f980fe0b80a77c 162 SUPERFAMILY SSF47240 7 160 2.71E-50 T 31-10-2018 IPR009078 Ferritin-like superfamily N186_00795 a1955bcf96b9555159f980fe0b80a77c 162 Gene3D G3DSA:1.20.1260.10 2 162 4.3E-47 T 31-10-2018 IPR012347 Ferritin-like N186_00795 a1955bcf96b9555159f980fe0b80a77c 162 Pfam PF00210 Ferritin-like domain 10 142 1.0E-37 T 31-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 N186_07940 74530a066890f5c92126652d49b5add0 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 302 3.3E-76 T 31-10-2018 IPR016040 NAD(P)-binding domain N186_07940 74530a066890f5c92126652d49b5add0 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 317 2.6E-131 T 31-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 N186_07940 74530a066890f5c92126652d49b5add0 333 SUPERFAMILY SSF51735 1 317 1.15E-91 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_07940 74530a066890f5c92126652d49b5add0 333 Gene3D G3DSA:3.90.25.10 190 311 1.4E-116 T 31-10-2018 N186_07940 74530a066890f5c92126652d49b5add0 333 Gene3D G3DSA:3.40.50.720 2 302 1.4E-116 T 31-10-2018 N186_07160 db3cc2e20a4a2b6719a1bd7a0bc19117 473 Pfam PF03600 Citrate transporter 60 407 6.2E-31 T 31-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 N186_06400 f970864457e38c7b64eea397ca46079c 187 Pfam PF03477 ATP cone domain 4 69 6.7E-10 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 N186_05940 96a96052d46230538063f12e8dca69b0 390 Pfam PF02163 Peptidase family M50 130 359 4.9E-19 T 31-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 N186_05940 96a96052d46230538063f12e8dca69b0 390 Gene3D G3DSA:2.30.42.10 221 309 4.0E-18 T 31-10-2018 N186_05940 96a96052d46230538063f12e8dca69b0 390 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 139 153 7.7E-18 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 N186_05940 96a96052d46230538063f12e8dca69b0 390 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 116 135 7.7E-18 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 N186_05940 96a96052d46230538063f12e8dca69b0 390 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 155 170 7.7E-18 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 N186_05940 96a96052d46230538063f12e8dca69b0 390 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 171 183 7.7E-18 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 N186_05940 96a96052d46230538063f12e8dca69b0 390 SMART SM00228 208 281 0.0022 T 31-10-2018 IPR001478 PDZ domain GO:0005515 N186_05940 96a96052d46230538063f12e8dca69b0 390 Pfam PF13180 PDZ domain 223 290 7.3E-11 T 31-10-2018 IPR001478 PDZ domain GO:0005515 N186_05940 96a96052d46230538063f12e8dca69b0 390 SUPERFAMILY SSF50156 222 312 3.46E-18 T 31-10-2018 IPR036034 PDZ superfamily GO:0005515 N186_08065 289655d28d9c97adb323111a55c98cc0 160 Gene3D G3DSA:1.20.120.330 48 159 7.6E-19 T 31-10-2018 N186_08065 289655d28d9c97adb323111a55c98cc0 160 Pfam PF05942 Archaeal PaREP1/PaREP8 family 48 148 8.6E-27 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_08335 8709012d2a72bc8600ed4bd60652b8a3 284 Gene3D G3DSA:1.10.3720.10 6 274 7.0E-45 T 31-10-2018 IPR035906 MetI-like superfamily N186_08335 8709012d2a72bc8600ed4bd60652b8a3 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 268 2.2E-8 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_08335 8709012d2a72bc8600ed4bd60652b8a3 284 SUPERFAMILY SSF161098 9 283 2.15E-49 T 31-10-2018 IPR035906 MetI-like superfamily N186_05590 0a75fbc083c36ad00f92ad5308ac01f9 143 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 29 99 1.5E-22 T 31-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative N186_08040 f00bf920b375f6241a7030ab180513aa 169 Gene3D G3DSA:3.40.50.720 5 164 7.2E-6 T 31-10-2018 N186_08040 f00bf920b375f6241a7030ab180513aa 169 SUPERFAMILY SSF51735 26 161 5.46E-8 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_01405 ceaccff28b4dc425c4b70b7993657c82 107 Pfam PF03692 Putative zinc- or iron-chelating domain 4 79 1.7E-9 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein N186_09020 f88e92a0eba060742fe69fd34ef29b6d 702 Pfam PF09826 Beta propeller domain 114 688 1.8E-109 T 31-10-2018 IPR019198 Beta propeller domain-containing family N186_00620 fd665f8bcd554b9589a2422cbfc02f0c 398 Gene3D G3DSA:1.20.5.340 298 366 1.2E-7 T 31-10-2018 N186_00620 fd665f8bcd554b9589a2422cbfc02f0c 398 SUPERFAMILY SSF58100 308 377 3.66E-5 T 31-10-2018 N186_00620 fd665f8bcd554b9589a2422cbfc02f0c 398 SUPERFAMILY SSF52317 25 126 6.87E-5 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like N186_04360 7616a3cc6c31d4624c5b6d27f916eee7 301 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 287 4.3E-41 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 N186_01265 cb40bea67dd30cc55842f6f7d679c940 193 Pfam PF09819 ABC-type cobalt transport system, permease component 9 126 2.3E-33 T 31-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted N186_05325 48f7fd40862187e96e448a6e680a7cc3 144 SUPERFAMILY SSF46966 12 113 6.4E-5 T 31-10-2018 N186_01920 d46f8c378abb91f4c0fe52becda4211e 197 SMART SM00981 77 162 1.5E-11 T 31-10-2018 IPR004114 THUMP domain GO:0003723 N186_01920 d46f8c378abb91f4c0fe52becda4211e 197 Pfam PF02926 THUMP domain 63 161 3.6E-13 T 31-10-2018 IPR004114 THUMP domain GO:0003723 N186_01920 d46f8c378abb91f4c0fe52becda4211e 197 Gene3D G3DSA:3.30.2300.10 86 162 4.7E-8 T 31-10-2018 N186_01920 d46f8c378abb91f4c0fe52becda4211e 197 SUPERFAMILY SSF143437 61 160 8.2E-12 T 31-10-2018 N186_08810 b3cc141528e51b1208a5f2cdd84884b5 366 Gene3D G3DSA:3.40.1710.10 41 132 1.9E-5 T 31-10-2018 N186_08810 b3cc141528e51b1208a5f2cdd84884b5 366 Pfam PF12698 ABC-2 family transporter protein 21 358 1.5E-46 T 31-10-2018 N186_02065 43283f714ec158bff9d39ea9ff8c4000 277 SUPERFAMILY SSF75217 14 272 3.4E-30 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases N186_02065 43283f714ec158bff9d39ea9ff8c4000 277 Gene3D G3DSA:2.40.50.140 98 164 4.5E-64 T 31-10-2018 N186_02065 43283f714ec158bff9d39ea9ff8c4000 277 Pfam PF02598 Putative RNA methyltransferase 12 268 1.4E-52 T 31-10-2018 IPR003750 Putative RNA methyltransferase N186_02065 43283f714ec158bff9d39ea9ff8c4000 277 Gene3D G3DSA:3.40.1280.10 13 270 4.5E-64 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal N186_02065 43283f714ec158bff9d39ea9ff8c4000 277 SUPERFAMILY SSF50249 96 164 2.57E-7 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold N186_00070 52bd509f666166ff6178938f3c47315d 231 Gene3D G3DSA:3.40.50.300 10 229 5.5E-11 T 31-10-2018 N186_00070 52bd509f666166ff6178938f3c47315d 231 SUPERFAMILY SSF52540 11 225 7.73E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04165 f80621007bdbc7b44f0f6ceeebc2d851 541 Pfam PF09843 Predicted membrane protein (DUF2070) 9 537 1.7E-88 T 31-10-2018 IPR019204 Domain of unknown function DUF2070, membrane N186_01795 0b660c3e07f1e5a0950c488b9a47d3be 98 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 77 9.6E-15 T 31-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 N186_01795 0b660c3e07f1e5a0950c488b9a47d3be 98 SUPERFAMILY SSF46785 2 95 3.12E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_01795 0b660c3e07f1e5a0950c488b9a47d3be 98 Gene3D G3DSA:1.10.10.10 1 98 3.0E-31 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04220 44ddfe3168b9aa9a6d1aa8828a511f21 269 Gene3D G3DSA:3.30.70.2990 1 112 1.5E-5 T 31-10-2018 N186_04220 44ddfe3168b9aa9a6d1aa8828a511f21 269 Gene3D G3DSA:3.30.70.1900 113 269 1.4E-32 T 31-10-2018 N186_04220 44ddfe3168b9aa9a6d1aa8828a511f21 269 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 127 262 1.3E-11 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal N186_07415 d92e0ec9a21b6538f71e98d1b376a45c 107 Gene3D G3DSA:3.10.530.10 32 100 5.3E-24 T 31-10-2018 IPR036593 CPE0013-like superfamily N186_07415 d92e0ec9a21b6538f71e98d1b376a45c 107 SUPERFAMILY SSF160148 32 105 1.57E-25 T 31-10-2018 IPR036593 CPE0013-like superfamily N186_07415 d92e0ec9a21b6538f71e98d1b376a45c 107 Pfam PF07892 Protein of unknown function (DUF1667) 22 99 1.9E-32 T 31-10-2018 IPR012460 Protein of unknown function DUF1667 N186_01775 d98b5e5b2f1cb417e04509b9d351df38 446 Gene3D G3DSA:3.30.2290.10 1 213 8.3E-6 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal N186_01775 d98b5e5b2f1cb417e04509b9d351df38 446 SUPERFAMILY SSF111283 5 439 3.27E-83 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 N186_01775 d98b5e5b2f1cb417e04509b9d351df38 446 Pfam PF01523 Putative modulator of DNA gyrase 27 307 2.1E-40 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 N186_09620 7770bb83bda80f59f2d38156f543eea1 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 317 2.0E-46 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 N186_02670 1c4b4ecb9cb6e689e26d5d91aa665b8f 230 Pfam PF09335 SNARE associated Golgi protein 44 154 5.8E-13 T 31-10-2018 IPR032816 SNARE associated Golgi protein N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 Gene3D G3DSA:3.60.20.10 11 198 2.0E-65 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 PRINTS PR00141 Proteasome component signature 149 160 5.4E-9 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 PRINTS PR00141 Proteasome component signature 174 185 5.4E-9 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 PRINTS PR00141 Proteasome component signature 18 33 5.4E-9 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 PRINTS PR00141 Proteasome component signature 138 149 5.4E-9 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 SUPERFAMILY SSF56235 6 196 5.9E-63 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 Hamap MF_02113_A Proteasome subunit beta [prcB]. 6 195 34.351 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 14 61 - T 31-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 10 193 6.6E-68 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 N186_02545 ee753e3be40b8dea695ca645b6ec7f7a 198 Pfam PF00227 Proteasome subunit 9 188 2.9E-56 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 N186_00680 7852989d2abf038683a73fb95ffedfdb 264 SUPERFAMILY SSF51735 8 259 1.26E-62 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily N186_00680 7852989d2abf038683a73fb95ffedfdb 264 Gene3D G3DSA:3.40.50.720 3 259 2.4E-60 T 31-10-2018 N186_00680 7852989d2abf038683a73fb95ffedfdb 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 258 5.5E-45 T 31-10-2018 N186_00680 7852989d2abf038683a73fb95ffedfdb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00680 7852989d2abf038683a73fb95ffedfdb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00680 7852989d2abf038683a73fb95ffedfdb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00680 7852989d2abf038683a73fb95ffedfdb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 5.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00680 7852989d2abf038683a73fb95ffedfdb 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR N186_00380 a30647fa5b681f46bccec12e78c11a01 430 Gene3D G3DSA:3.40.50.12780 29 264 1.5E-12 T 31-10-2018 N186_07655 e7509c26be9a012ccd126d3a09e73239 59 SUPERFAMILY SSF81301 9 55 2.07E-5 T 31-10-2018 N186_05660 56b8e27a65b8090293ce4146668efbdd 153 SUPERFAMILY SSF53738 10 64 7.65E-6 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 N186_05660 56b8e27a65b8090293ce4146668efbdd 153 Gene3D G3DSA:3.40.120.10 1 68 8.0E-8 T 31-10-2018 N186_06310 e5fc8cbeea76c55434b89201ec8ff0bc 358 SUPERFAMILY SSF53474 20 356 5.76E-39 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_06310 e5fc8cbeea76c55434b89201ec8ff0bc 358 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 3.0E-7 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_06310 e5fc8cbeea76c55434b89201ec8ff0bc 358 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 3.0E-7 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_06310 e5fc8cbeea76c55434b89201ec8ff0bc 358 Gene3D G3DSA:3.40.50.1820 13 358 1.4E-40 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold N186_06310 e5fc8cbeea76c55434b89201ec8ff0bc 358 PRINTS PR00412 Epoxide hydrolase signature 334 356 4.5E-7 T 31-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 N186_06310 e5fc8cbeea76c55434b89201ec8ff0bc 358 PRINTS PR00412 Epoxide hydrolase signature 60 75 4.5E-7 T 31-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 N186_06310 e5fc8cbeea76c55434b89201ec8ff0bc 358 PRINTS PR00412 Epoxide hydrolase signature 106 119 4.5E-7 T 31-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 N186_06310 e5fc8cbeea76c55434b89201ec8ff0bc 358 Pfam PF12697 Alpha/beta hydrolase family 37 349 5.0E-20 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 N186_00740 544d02cb5eac708a1cc551d91c14ee3a 470 SUPERFAMILY SSF53448 58 323 4.02E-20 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_00740 544d02cb5eac708a1cc551d91c14ee3a 470 Gene3D G3DSA:3.90.550.10 45 263 2.5E-16 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_00740 544d02cb5eac708a1cc551d91c14ee3a 470 Pfam PF13632 Glycosyl transferase family group 2 142 351 9.5E-17 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 N186_06090 d406488ae2e4c861f29aa6a23e7bea3f 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 210 3.3E-18 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_06090 d406488ae2e4c861f29aa6a23e7bea3f 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 105 2.4E-25 T 31-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 N186_06090 d406488ae2e4c861f29aa6a23e7bea3f 218 SUPERFAMILY SSF161098 12 202 1.44E-43 T 31-10-2018 IPR035906 MetI-like superfamily N186_06090 d406488ae2e4c861f29aa6a23e7bea3f 218 Gene3D G3DSA:1.10.3720.10 1 211 1.2E-53 T 31-10-2018 IPR035906 MetI-like superfamily N186_04645 04f94f6a35ff440cc0c864b4ec868174 194 Hamap MF_01111 UPF0200 protein . 9 186 30.067 T 31-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related N186_04645 04f94f6a35ff440cc0c864b4ec868174 194 SUPERFAMILY SSF52540 8 186 6.88E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04645 04f94f6a35ff440cc0c864b4ec868174 194 Pfam PF13207 AAA domain 13 135 4.0E-15 T 31-10-2018 N186_04645 04f94f6a35ff440cc0c864b4ec868174 194 Gene3D G3DSA:3.40.50.300 8 186 6.7E-38 T 31-10-2018 N186_05700 26f93ff16239cd3019d94c554a290d74 418 Gene3D G3DSA:3.90.226.10 25 217 1.2E-33 T 31-10-2018 N186_05700 26f93ff16239cd3019d94c554a290d74 418 Pfam PF01957 NfeD-like C-terminal, partner-binding 269 407 1.5E-23 T 31-10-2018 IPR002810 NfeD-like, C-terminal domain N186_05700 26f93ff16239cd3019d94c554a290d74 418 Gene3D G3DSA:2.40.50.140 339 414 1.9E-14 T 31-10-2018 N186_05700 26f93ff16239cd3019d94c554a290d74 418 SUPERFAMILY SSF52096 9 176 2.43E-17 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily N186_05700 26f93ff16239cd3019d94c554a290d74 418 SUPERFAMILY SSF141322 341 408 2.88E-11 T 31-10-2018 N186_00485 4eba3850e1842a134ea449897a8d7701 270 Gene3D G3DSA:1.10.3720.10 2 256 4.1E-46 T 31-10-2018 IPR035906 MetI-like superfamily N186_00485 4eba3850e1842a134ea449897a8d7701 270 SUPERFAMILY SSF161098 6 260 2.9E-53 T 31-10-2018 IPR035906 MetI-like superfamily N186_00485 4eba3850e1842a134ea449897a8d7701 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 254 1.5E-15 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_02415 1f8ff8528326a4eb06745295b3cf8c93 423 Gene3D G3DSA:3.40.50.2300 171 307 1.4E-57 T 31-10-2018 N186_02415 1f8ff8528326a4eb06745295b3cf8c93 423 Pfam PF01094 Receptor family ligand binding region 72 400 4.6E-46 T 31-10-2018 IPR001828 Receptor, ligand binding region N186_02415 1f8ff8528326a4eb06745295b3cf8c93 423 PRINTS PR01176 Metabotropic gamma-aminobutyric acid type B receptor signature 68 84 6.8E-7 T 31-10-2018 N186_02415 1f8ff8528326a4eb06745295b3cf8c93 423 PRINTS PR01176 Metabotropic gamma-aminobutyric acid type B receptor signature 129 157 6.8E-7 T 31-10-2018 N186_02415 1f8ff8528326a4eb06745295b3cf8c93 423 PRINTS PR01176 Metabotropic gamma-aminobutyric acid type B receptor signature 339 351 6.8E-7 T 31-10-2018 N186_02415 1f8ff8528326a4eb06745295b3cf8c93 423 Gene3D G3DSA:3.40.50.2300 54 377 1.4E-57 T 31-10-2018 N186_02415 1f8ff8528326a4eb06745295b3cf8c93 423 SUPERFAMILY SSF53822 51 414 7.07E-65 T 31-10-2018 IPR028082 Periplasmic binding protein-like I N186_06030 6a0e31e98b500bfa93c9d63c66aab540 247 Pfam PF09973 Predicted membrane protein (DUF2208) 8 242 1.3E-56 T 31-10-2018 IPR009198 Uncharacterised conserved protein UCP014484, transmembrane N186_07755 20fd571abbe0157c95f996488c57f3e8 130 SUPERFAMILY SSF81593 6 128 7.46E-34 T 31-10-2018 N186_07755 20fd571abbe0157c95f996488c57f3e8 130 Pfam PF05168 HEPN domain 6 127 1.0E-29 T 31-10-2018 IPR007842 HEPN domain N186_07755 20fd571abbe0157c95f996488c57f3e8 130 Gene3D G3DSA:1.20.120.330 3 130 1.1E-32 T 31-10-2018 N186_07755 20fd571abbe0157c95f996488c57f3e8 130 SMART SM00748 10 121 2.9E-30 T 31-10-2018 IPR007842 HEPN domain N186_05040 25ba2ed445c21d2cfe62ac36afc9f3b7 121 SMART SM00651 26 92 1.9E-18 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type N186_05040 25ba2ed445c21d2cfe62ac36afc9f3b7 121 Pfam PF01423 LSM domain 27 91 8.6E-18 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type N186_05040 25ba2ed445c21d2cfe62ac36afc9f3b7 121 SUPERFAMILY SSF50182 24 111 4.78E-20 T 31-10-2018 IPR010920 LSM domain superfamily N186_05040 25ba2ed445c21d2cfe62ac36afc9f3b7 121 Gene3D G3DSA:2.30.30.100 19 107 3.4E-21 T 31-10-2018 N186_08945 521083a906a94e7481c35569ab56c1f8 433 TIGRFAM TIGR00797 matE: MATE efflux family protein 11 402 6.0E-52 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 N186_08945 521083a906a94e7481c35569ab56c1f8 433 PIRSF PIRSF006603 1 432 2.4E-55 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 N186_08945 521083a906a94e7481c35569ab56c1f8 433 Pfam PF01554 MatE 230 385 1.9E-19 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 N186_08945 521083a906a94e7481c35569ab56c1f8 433 Pfam PF01554 MatE 11 169 1.5E-19 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 N186_05435 5cf93944a0975403900032cda508beac 374 SUPERFAMILY SSF51905 1 286 3.37E-14 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_05435 5cf93944a0975403900032cda508beac 374 Gene3D G3DSA:3.50.50.60 4 312 1.9E-42 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily N186_05435 5cf93944a0975403900032cda508beac 374 Gene3D G3DSA:3.30.9.10 70 329 1.9E-42 T 31-10-2018 N186_07710 8b106302bd11ed57683834e50673a8bc 151 Pfam PF03551 Transcriptional regulator PadR-like family 15 85 3.7E-18 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal N186_07710 8b106302bd11ed57683834e50673a8bc 151 SUPERFAMILY SSF46785 4 97 1.1E-24 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_07710 8b106302bd11ed57683834e50673a8bc 151 Gene3D G3DSA:1.10.10.10 1 109 1.5E-25 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_04055 32372d6269a20da0e677a0458e834195 380 Gene3D G3DSA:3.40.50.1980 38 186 7.4E-39 T 31-10-2018 N186_04055 32372d6269a20da0e677a0458e834195 380 Pfam PF01497 Periplasmic binding protein 62 309 7.8E-27 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain N186_04055 32372d6269a20da0e677a0458e834195 380 Gene3D G3DSA:3.40.50.1980 187 377 4.2E-65 T 31-10-2018 N186_04055 32372d6269a20da0e677a0458e834195 380 SUPERFAMILY SSF53807 41 336 1.49E-47 T 31-10-2018 N186_08120 4e6e6670a25884710e7c67de6ccd473e 411 SUPERFAMILY SSF52540 30 196 1.52E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08120 4e6e6670a25884710e7c67de6ccd473e 411 Gene3D G3DSA:3.40.50.300 6 148 1.0E-5 T 31-10-2018 N186_08120 4e6e6670a25884710e7c67de6ccd473e 411 Pfam PF13635 Domain of unknown function (DUF4143) 208 351 4.4E-13 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 N186_08120 4e6e6670a25884710e7c67de6ccd473e 411 Pfam PF13173 AAA domain 32 156 2.9E-29 T 31-10-2018 N186_09140 04f3677d9745912f7383406f71c288c0 76 SUPERFAMILY SSF89447 3 43 4.06E-5 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_09590 3a3cf5c7d022df84cd4c0a0bd4e1dc81 184 Gene3D G3DSA:1.10.490.10 4 150 4.3E-9 T 31-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 N186_03695 68419e622b79ce67a622e07b4aeeeb99 459 Pfam PF09369 Domain of unknown function (DUF1998) 345 428 5.4E-7 T 31-10-2018 IPR018973 DEAD/DEAH-box helicase, putative N186_01535 fa01f6929da8743706cb54a39573b6fa 274 Pfam PF00950 ABC 3 transport family 24 269 9.2E-26 T 31-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 N186_01535 fa01f6929da8743706cb54a39573b6fa 274 SUPERFAMILY SSF81345 7 270 4.05E-17 T 31-10-2018 IPR037294 ABC transporter, BtuC-like N186_01535 fa01f6929da8743706cb54a39573b6fa 274 Gene3D G3DSA:1.10.3470.10 42 274 2.8E-8 T 31-10-2018 IPR037294 ABC transporter, BtuC-like N186_09425 ad8d792903cae9312855c4539ba2be03 281 Gene3D G3DSA:3.40.50.1580 11 264 5.7E-86 T 31-10-2018 N186_09425 ad8d792903cae9312855c4539ba2be03 281 SUPERFAMILY SSF53167 22 251 3.53E-75 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 N186_09425 ad8d792903cae9312855c4539ba2be03 281 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 22 261 3.1E-102 T 31-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 N186_09425 ad8d792903cae9312855c4539ba2be03 281 Pfam PF01048 Phosphorylase superfamily 35 256 1.1E-43 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 N186_01475 4b32f9231bca7601e140dd897b71082f 266 Gene3D G3DSA:1.10.3210.10 25 204 2.7E-12 T 31-10-2018 N186_01475 4b32f9231bca7601e140dd897b71082f 266 SUPERFAMILY SSF109604 55 194 1.32E-10 T 31-10-2018 N186_01475 4b32f9231bca7601e140dd897b71082f 266 Pfam PF01966 HD domain 94 180 3.4E-5 T 31-10-2018 IPR006674 HD domain N186_01475 4b32f9231bca7601e140dd897b71082f 266 SMART SM00471 52 190 3.1E-5 T 31-10-2018 IPR003607 HD/PDEase domain N186_05355 1e6ee7f1a4c52edca477f549bafab4bb 111 SUPERFAMILY SSF46785 7 108 1.93E-24 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_05355 1e6ee7f1a4c52edca477f549bafab4bb 111 Gene3D G3DSA:2.20.28.10 6 110 9.4E-24 T 31-10-2018 N186_06315 38c574235c7fb4b275cc952d1909da70 285 PRINTS PR00069 Aldo-keto reductase signature 177 206 3.1E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 N186_06315 38c574235c7fb4b275cc952d1909da70 285 PRINTS PR00069 Aldo-keto reductase signature 140 157 3.1E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 N186_06315 38c574235c7fb4b275cc952d1909da70 285 PRINTS PR00069 Aldo-keto reductase signature 53 77 3.1E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 N186_06315 38c574235c7fb4b275cc952d1909da70 285 PRINTS PR00069 Aldo-keto reductase signature 109 127 3.1E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 N186_06315 38c574235c7fb4b275cc952d1909da70 285 PRINTS PR00069 Aldo-keto reductase signature 214 238 3.1E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 N186_06315 38c574235c7fb4b275cc952d1909da70 285 SUPERFAMILY SSF51430 17 281 2.62E-76 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily N186_06315 38c574235c7fb4b275cc952d1909da70 285 Pfam PF00248 Aldo/keto reductase family 24 277 1.5E-54 T 31-10-2018 IPR023210 NADP-dependent oxidoreductase domain N186_06315 38c574235c7fb4b275cc952d1909da70 285 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 140 157 - T 31-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 N186_06315 38c574235c7fb4b275cc952d1909da70 285 Gene3D G3DSA:3.20.20.100 11 279 1.7E-81 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily N186_09420 cc073dde6949ee279da0d5b065e61203 445 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 43 201 6.6E-19 T 31-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 N186_09420 cc073dde6949ee279da0d5b065e61203 445 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 235 335 6.6E-9 T 31-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 N186_09420 cc073dde6949ee279da0d5b065e61203 445 Gene3D G3DSA:3.40.50.2300 155 375 1.9E-60 T 31-10-2018 N186_09420 cc073dde6949ee279da0d5b065e61203 445 Gene3D G3DSA:3.40.50.2300 43 345 1.9E-60 T 31-10-2018 N186_04590 5e7c5beef88c3f66015da0dfc32f2fb6 206 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 3 193 32.326 T 31-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 N186_04590 5e7c5beef88c3f66015da0dfc32f2fb6 206 SMART SM01397 3 193 2.1E-91 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_04590 5e7c5beef88c3f66015da0dfc32f2fb6 206 Pfam PF01015 Ribosomal S3Ae family 5 191 8.2E-64 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05430 a3d9f62a3682cc4bd489d37ad5da5f71 196 SUPERFAMILY SSF53323 4 191 5.36E-36 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 N186_05430 a3d9f62a3682cc4bd489d37ad5da5f71 196 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 188 8.8E-34 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 N186_05430 a3d9f62a3682cc4bd489d37ad5da5f71 196 Gene3D G3DSA:3.40.920.10 4 195 6.6E-39 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 N186_08975 aec43107799ab62b3959ec45b5b9d3fc 148 Pfam PF00578 AhpC/TSA family 7 126 6.0E-39 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 N186_08975 aec43107799ab62b3959ec45b5b9d3fc 148 SUPERFAMILY SSF52833 2 148 6.26E-49 T 31-10-2018 IPR036249 Thioredoxin-like superfamily N186_08975 aec43107799ab62b3959ec45b5b9d3fc 148 PIRSF PIRSF000239 1 143 8.0E-32 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 N186_08975 aec43107799ab62b3959ec45b5b9d3fc 148 Gene3D G3DSA:3.40.30.10 2 148 7.4E-45 T 31-10-2018 N186_04410 e26d87ce56ed91da9a5c2fc359c61833 407 Gene3D G3DSA:3.30.70.260 331 406 2.0E-5 T 31-10-2018 N186_04410 e26d87ce56ed91da9a5c2fc359c61833 407 SUPERFAMILY SSF53686 13 316 7.33E-103 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme N186_04410 e26d87ce56ed91da9a5c2fc359c61833 407 Gene3D G3DSA:3.40.50.1100 57 152 5.7E-121 T 31-10-2018 N186_04410 e26d87ce56ed91da9a5c2fc359c61833 407 SUPERFAMILY SSF55021 332 405 3.15E-6 T 31-10-2018 N186_04410 e26d87ce56ed91da9a5c2fc359c61833 407 Gene3D G3DSA:3.40.50.1100 14 313 5.7E-121 T 31-10-2018 N186_04410 e26d87ce56ed91da9a5c2fc359c61833 407 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 28 406 9.6E-153 T 31-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 N186_04410 e26d87ce56ed91da9a5c2fc359c61833 407 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 308 5.2E-84 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme N186_07880 7461fb8c7fd8a0c8af4b551ea465f525 261 Gene3D G3DSA:1.20.120.580 1 129 1.8E-18 T 31-10-2018 IPR037038 Bsu32300-like superfamily N186_07880 7461fb8c7fd8a0c8af4b551ea465f525 261 Pfam PF01934 Protein of unknown function DUF86 20 107 1.0E-14 T 31-10-2018 IPR008201 Protein of unknown function DUF86 N186_07880 7461fb8c7fd8a0c8af4b551ea465f525 261 SUPERFAMILY SSF81301 137 223 9.81E-7 T 31-10-2018 N186_08615 b3b0d4104720b80f256a4c7a6102b9d3 254 SUPERFAMILY SSF57997 35 142 2.88E-6 T 31-10-2018 N186_08615 b3b0d4104720b80f256a4c7a6102b9d3 254 Gene3D G3DSA:1.20.5.190 87 135 4.5E-7 T 31-10-2018 N186_08615 b3b0d4104720b80f256a4c7a6102b9d3 254 Gene3D G3DSA:1.20.5.190 49 86 3.6E-9 T 31-10-2018 N186_05695 e480384b3fc80c8d1445a3b5c4997759 274 Pfam PF01940 Integral membrane protein DUF92 18 264 6.3E-55 T 31-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 N186_09305 5c58d46e4cc1d94ec51549cd88ff9e73 270 Gene3D G3DSA:3.40.50.10770 10 210 5.3E-47 T 31-10-2018 N186_09305 5c58d46e4cc1d94ec51549cd88ff9e73 270 Pfam PF09651 CRISPR-associated protein (Cas_APE2256) 77 206 5.3E-31 T 31-10-2018 IPR013442 CRISPR-associated protein APE2256 N186_09305 5c58d46e4cc1d94ec51549cd88ff9e73 270 TIGRFAM TIGR02619 TIGR02619: putative CRISPR-associated protein, APE2256 family 73 207 5.3E-25 T 31-10-2018 IPR013442 CRISPR-associated protein APE2256 N186_09305 5c58d46e4cc1d94ec51549cd88ff9e73 270 Gene3D G3DSA:1.10.196.30 15 65 5.3E-47 T 31-10-2018 N186_08745 639c0c57a41b12e7b3aa65d4281a3fdc 541 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 16 529 1.1E-71 T 31-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 N186_09210 024660f9c3d38114e90f20d25409aad2 1066 Pfam PF04465 Protein of unknown function (DUF499) 113 944 2.3E-176 T 31-10-2018 IPR007555 Protein of unknown function DUF499 N186_01695 a1757153ac122389593d0a010b9540c9 214 SMART SM00849 15 187 0.0089 T 31-10-2018 IPR001279 Metallo-beta-lactamase N186_01695 a1757153ac122389593d0a010b9540c9 214 Pfam PF13483 Beta-lactamase superfamily domain 11 187 5.6E-30 T 31-10-2018 N186_01695 a1757153ac122389593d0a010b9540c9 214 SUPERFAMILY SSF56281 10 193 1.3E-24 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_01695 a1757153ac122389593d0a010b9540c9 214 Gene3D G3DSA:3.60.15.10 8 214 2.8E-50 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_03390 f2e007a19cfcf39f2214d211bf128119 151 Gene3D G3DSA:3.90.470.10 3 151 4.4E-47 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 N186_03390 f2e007a19cfcf39f2214d211bf128119 151 Pfam PF00237 Ribosomal protein L22p/L17e 18 146 4.5E-28 T 31-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 N186_03390 f2e007a19cfcf39f2214d211bf128119 151 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 9 149 9.9E-53 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_03390 f2e007a19cfcf39f2214d211bf128119 151 SUPERFAMILY SSF54843 4 147 4.58E-44 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 N186_03390 f2e007a19cfcf39f2214d211bf128119 151 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 2 150 33.403 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 N186_05290 8d1309a3fdd0cae0b2349fe49c678310 89 Pfam PF04457 Protein of unknown function (DUF504) 25 82 2.9E-13 T 31-10-2018 IPR007547 Uncharacterised protein family UPF0248 N186_00170 3102ecca436581f36c993457f2221aca 207 Pfam PF01988 VIT family 92 205 6.3E-8 T 31-10-2018 IPR008217 Ccc1 family N186_04230 007602bc2f13629de0623ae8274f0400 234 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 8 231 1.1E-78 T 31-10-2018 IPR018693 Protein of unknown function DUF2192 N186_02580 4a45f330d0cd71000b8698f921c4decd 84 SUPERFAMILY SSF54285 5 84 9.91E-13 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp N186_02580 4a45f330d0cd71000b8698f921c4decd 84 Pfam PF02597 ThiS family 7 84 1.4E-9 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 N186_02580 4a45f330d0cd71000b8698f921c4decd 84 Gene3D G3DSA:3.10.20.30 2 84 3.7E-13 T 31-10-2018 IPR012675 Beta-grasp domain superfamily N186_09015 2c4d5d8c58ca6b9e45e81024694a3288 105 Pfam PF01909 Nucleotidyltransferase domain 20 61 2.7E-10 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 N186_09015 2c4d5d8c58ca6b9e45e81024694a3288 105 SUPERFAMILY SSF81301 20 94 6.78E-17 T 31-10-2018 N186_09015 2c4d5d8c58ca6b9e45e81024694a3288 105 Gene3D G3DSA:3.30.460.10 17 104 1.4E-25 T 31-10-2018 N186_01255 18c48f82a087589070f2fcf55bfa5c2e 235 Pfam PF02361 Cobalt transport protein 2 202 1.7E-11 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component N186_01740 114fc5f764543d556017c12fcb088aaf 300 Pfam PF13559 Domain of unknown function (DUF4129) 217 286 4.9E-7 T 31-10-2018 IPR025403 Domain of unknown function DUF4129 N186_03260 bab1a3041fe63e8af760ef03e23c2715 175 Gene3D G3DSA:3.40.1280.10 6 173 8.9E-14 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal N186_03260 bab1a3041fe63e8af760ef03e23c2715 175 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 24 105 5.1E-10 T 31-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 N186_03260 bab1a3041fe63e8af760ef03e23c2715 175 SUPERFAMILY SSF75217 11 145 2.22E-10 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases N186_04375 d159d8b767c29382185877c73c7016dd 144 PIRSF PIRSF004681 9 144 1.5E-38 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 N186_04375 d159d8b767c29382185877c73c7016dd 144 SUPERFAMILY SSF111038 9 144 3.01E-45 T 31-10-2018 IPR035917 YjbQ-like superfamily N186_04375 d159d8b767c29382185877c73c7016dd 144 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 105 123 - T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 N186_04375 d159d8b767c29382185877c73c7016dd 144 Gene3D G3DSA:2.60.120.460 2 144 6.8E-53 T 31-10-2018 IPR035917 YjbQ-like superfamily N186_04375 d159d8b767c29382185877c73c7016dd 144 Pfam PF01894 Uncharacterised protein family UPF0047 27 140 7.8E-37 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 N186_04375 d159d8b767c29382185877c73c7016dd 144 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 14 144 1.6E-43 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 N186_02215 1ce389e5644b3267727d081ce1ae7d6e 290 Gene3D G3DSA:3.40.630.30 8 151 1.2E-17 T 31-10-2018 N186_02215 1ce389e5644b3267727d081ce1ae7d6e 290 Pfam PF00583 Acetyltransferase (GNAT) family 42 120 6.1E-9 T 31-10-2018 IPR000182 GNAT domain N186_02215 1ce389e5644b3267727d081ce1ae7d6e 290 SUPERFAMILY SSF55729 8 125 1.22E-17 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase N186_08215 cd27297ad71f66e75d849fe98910edc9 242 SUPERFAMILY SSF52540 3 214 2.52E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_08215 cd27297ad71f66e75d849fe98910edc9 242 Gene3D G3DSA:3.40.50.300 4 216 7.9E-46 T 31-10-2018 N186_08215 cd27297ad71f66e75d849fe98910edc9 242 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 18 190 1.1E-33 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 N186_00055 19eb0c1aa4255ba0c577effcfa70f414 79 Gene3D G3DSA:2.10.260.10 3 44 3.1E-11 T 31-10-2018 N186_00055 19eb0c1aa4255ba0c577effcfa70f414 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 49 1.5E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_00055 19eb0c1aa4255ba0c577effcfa70f414 79 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 46 3.2E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_00055 19eb0c1aa4255ba0c577effcfa70f414 79 SUPERFAMILY SSF89447 3 49 2.27E-12 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_00055 19eb0c1aa4255ba0c577effcfa70f414 79 SMART SM00966 6 51 7.4E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_00890 7dd8edd43f85c4e3342ee2ee39a9ab2c 255 Pfam PF02361 Cobalt transport protein 10 215 1.4E-18 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component N186_06750 28f9e87a00ce9a1cbf881a5f6ffffa97 335 Gene3D G3DSA:3.40.50.2020 74 223 8.0E-9 T 31-10-2018 N186_06750 28f9e87a00ce9a1cbf881a5f6ffffa97 335 SUPERFAMILY SSF53271 86 202 1.15E-5 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_05580 82dfb25acc06c41eb3bb402789fc68f6 381 SUPERFAMILY SSF56112 53 356 1.05E-13 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily N186_05580 82dfb25acc06c41eb3bb402789fc68f6 381 Gene3D G3DSA:3.90.1200.10 126 379 1.4E-31 T 31-10-2018 N186_01115 43bc30fe625f8d6208d6d8b8bc85fb1f 74 Pfam PF02697 Putative antitoxin 2 61 1.4E-11 T 31-10-2018 IPR003847 Putative antitoxin N186_01115 43bc30fe625f8d6208d6d8b8bc85fb1f 74 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 2 63 2.0E-4 T 31-10-2018 IPR003847 Putative antitoxin N186_00430 68c1757a2145c2849df8d71cc89a72e4 217 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 32 211 32.29 T 31-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 N186_00430 68c1757a2145c2849df8d71cc89a72e4 217 SUPERFAMILY SSF56399 35 212 9.21E-48 T 31-10-2018 N186_00430 68c1757a2145c2849df8d71cc89a72e4 217 Gene3D G3DSA:1.10.10.970 32 108 1.0E-23 T 31-10-2018 N186_00430 68c1757a2145c2849df8d71cc89a72e4 217 Gene3D G3DSA:3.20.170.30 130 216 6.2E-29 T 31-10-2018 N186_00430 68c1757a2145c2849df8d71cc89a72e4 217 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 33 202 5.5E-25 T 31-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 N186_00920 74f34142fabeb4898427eda58077c4be 499 SUPERFAMILY SSF161098 6 198 3.79E-18 T 31-10-2018 IPR035906 MetI-like superfamily N186_00920 74f34142fabeb4898427eda58077c4be 499 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 203 5.5E-10 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_00920 74f34142fabeb4898427eda58077c4be 499 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 312 488 1.4E-13 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_00920 74f34142fabeb4898427eda58077c4be 499 SUPERFAMILY SSF161098 291 482 7.06E-14 T 31-10-2018 IPR035906 MetI-like superfamily N186_00920 74f34142fabeb4898427eda58077c4be 499 Pfam PF12805 FUSC-like inner membrane protein yccS 358 404 7.9E-5 T 31-10-2018 IPR032692 Integral membrane protein YccS, N-terminal N186_00920 74f34142fabeb4898427eda58077c4be 499 Gene3D G3DSA:1.10.3720.10 5 205 7.7E-18 T 31-10-2018 IPR035906 MetI-like superfamily N186_00920 74f34142fabeb4898427eda58077c4be 499 Gene3D G3DSA:1.10.3720.10 284 493 1.8E-17 T 31-10-2018 IPR035906 MetI-like superfamily N186_09440 fedc2f39dcf2c8ff4b7f24fc5e82d413 181 Gene3D G3DSA:2.30.110.10 2 177 7.5E-44 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 N186_09440 fedc2f39dcf2c8ff4b7f24fc5e82d413 181 SMART SM00903 8 147 1.4E-20 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 N186_09440 fedc2f39dcf2c8ff4b7f24fc5e82d413 181 Pfam PF01613 Flavin reductase like domain 11 143 5.3E-19 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 N186_09440 fedc2f39dcf2c8ff4b7f24fc5e82d413 181 SUPERFAMILY SSF50475 4 171 1.91E-34 T 31-10-2018 N186_09050 847c84b796c6d9389c48ca33199746bc 197 Gene3D G3DSA:1.10.1760.20 12 196 7.2E-6 T 31-10-2018 N186_07105 73df158528aa23de536f9117c4ce4aae 141 SUPERFAMILY SSF103481 46 140 1.7E-11 T 31-10-2018 N186_07105 73df158528aa23de536f9117c4ce4aae 141 Pfam PF00892 EamA-like transporter family 6 139 5.6E-20 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 N186_02760 f86ec30e8084e485875af4d3b65bffe4 86 SMART SM00803 14 76 0.0059 T 31-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 N186_02760 f86ec30e8084e485875af4d3b65bffe4 86 Gene3D G3DSA:1.10.20.10 10 75 8.6E-21 T 31-10-2018 IPR009072 Histone-fold GO:0046982 N186_02760 f86ec30e8084e485875af4d3b65bffe4 86 SUPERFAMILY SSF47113 7 80 7.45E-20 T 31-10-2018 IPR009072 Histone-fold GO:0046982 N186_02760 f86ec30e8084e485875af4d3b65bffe4 86 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 12 74 3.3E-16 T 31-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain N186_09570 93354da82d89c51cb24efe7379e21f84 533 Gene3D G3DSA:3.40.50.300 281 508 3.5E-52 T 31-10-2018 N186_09570 93354da82d89c51cb24efe7379e21f84 533 Pfam PF01935 Domain of unknown function DUF87 140 366 7.1E-46 T 31-10-2018 IPR002789 Helicase HerA, central domain N186_09570 93354da82d89c51cb24efe7379e21f84 533 SUPERFAMILY SSF52540 131 499 7.54E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01245 546109ea759a3575e1656bd6ce703273 173 Gene3D G3DSA:1.10.1760.20 5 163 6.3E-32 T 31-10-2018 N186_01245 546109ea759a3575e1656bd6ce703273 173 Pfam PF07155 ECF-type riboflavin transporter, S component 11 160 1.1E-26 T 31-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 N186_04960 d0b46c1c6faa3c39c517754244674e3a 350 SMART SM00382 61 296 0.0018 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_04960 d0b46c1c6faa3c39c517754244674e3a 350 Pfam PF01935 Domain of unknown function DUF87 48 101 3.2E-8 T 31-10-2018 IPR002789 Helicase HerA, central domain N186_04960 d0b46c1c6faa3c39c517754244674e3a 350 SUPERFAMILY SSF52540 36 344 7.2E-31 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_04010 382c9aba2c0461c3dc67144606ca0971 278 Gene3D G3DSA:3.20.20.70 3 181 9.1E-13 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_04010 382c9aba2c0461c3dc67144606ca0971 278 Pfam PF04055 Radical SAM superfamily 20 140 1.2E-7 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 N186_04010 382c9aba2c0461c3dc67144606ca0971 278 SUPERFAMILY SSF102114 17 178 8.04E-13 T 31-10-2018 N186_00970 21f6befdbbb4688f8bb3c31846424c63 162 Gene3D G3DSA:3.10.20.490 51 160 1.1E-9 T 31-10-2018 N186_00970 21f6befdbbb4688f8bb3c31846424c63 162 Pfam PF14478 Domain of unknown function (DUF4430) 80 159 2.0E-8 T 31-10-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 N186_03420 c9e54a35184a0bafe42f74853ea23d9b 229 SUPERFAMILY SSF52980 82 144 1.72E-12 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_03420 c9e54a35184a0bafe42f74853ea23d9b 229 Gene3D G3DSA:3.40.1350.10 79 192 6.4E-6 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 N186_09745 e4950ebcf176380155cad312d72219c9 100 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 61 81 - T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 N186_07355 22f9e1d878ba7a334a5cc0d1b27de25e 134 Gene3D G3DSA:3.40.50.150 6 133 1.9E-15 T 31-10-2018 N186_07355 22f9e1d878ba7a334a5cc0d1b27de25e 134 SUPERFAMILY SSF53335 11 107 9.79E-9 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_07750 8d8cd239bfd898426f89bde66f52aa56 201 Gene3D G3DSA:2.30.30.60 148 195 2.4E-10 T 31-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily N186_07750 8d8cd239bfd898426f89bde66f52aa56 201 SUPERFAMILY SSF50182 133 194 1.41E-13 T 31-10-2018 IPR010920 LSM domain superfamily N186_07750 8d8cd239bfd898426f89bde66f52aa56 201 Pfam PF00924 Mechanosensitive ion channel 116 194 2.4E-19 T 31-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 N186_02745 76290b6276c97501f4ab302cb39a4f64 640 Pfam PF13620 Carboxypeptidase regulatory-like domain 518 591 2.9E-10 T 31-10-2018 N186_02745 76290b6276c97501f4ab302cb39a4f64 640 Gene3D G3DSA:2.60.40.10 517 595 4.4E-7 T 31-10-2018 IPR013783 Immunoglobulin-like fold N186_02745 76290b6276c97501f4ab302cb39a4f64 640 SUPERFAMILY SSF49478 524 578 3.84E-8 T 31-10-2018 N186_00780 94ccdb3095cc3d1c854422ba6d1addcb 328 SUPERFAMILY SSF55681 36 324 3.67E-42 T 31-10-2018 N186_00780 94ccdb3095cc3d1c854422ba6d1addcb 328 Pfam PF00152 tRNA synthetases class II (D, K and N) 36 321 2.0E-31 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 N186_00780 94ccdb3095cc3d1c854422ba6d1addcb 328 Gene3D G3DSA:3.30.930.10 29 326 1.4E-54 T 31-10-2018 N186_08255 f493c1c8479d0afef1c3d8826eff5121 426 Pfam PF03600 Citrate transporter 29 363 5.7E-24 T 31-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 N186_01570 4708bd5fc8c83b34cf37878a04837b04 79 Gene3D G3DSA:3.30.70.20 2 77 3.1E-21 T 31-10-2018 N186_01570 4708bd5fc8c83b34cf37878a04837b04 79 SUPERFAMILY SSF54862 4 77 4.4E-10 T 31-10-2018 N186_01570 4708bd5fc8c83b34cf37878a04837b04 79 PRINTS PR00352 3Fe-4S ferredoxin signature 8 19 2.7E-7 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 N186_01570 4708bd5fc8c83b34cf37878a04837b04 79 PRINTS PR00352 3Fe-4S ferredoxin signature 61 73 2.7E-7 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 N186_01570 4708bd5fc8c83b34cf37878a04837b04 79 PRINTS PR00352 3Fe-4S ferredoxin signature 19 29 2.7E-7 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 N186_01570 4708bd5fc8c83b34cf37878a04837b04 79 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 8 75 1.9E-21 T 31-10-2018 N186_08765 aa95a238595ae567cb667b550729d715 195 Pfam PF02517 CAAX protease self-immunity 100 183 1.9E-4 T 31-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 N186_00645 0dd8e0506fab34e785dea845aa9f34e8 210 Gene3D G3DSA:3.40.50.2020 3 203 6.3E-64 T 31-10-2018 N186_00645 0dd8e0506fab34e785dea845aa9f34e8 210 Pfam PF00156 Phosphoribosyl transferase domain 7 194 3.9E-24 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 N186_00645 0dd8e0506fab34e785dea845aa9f34e8 210 Gene3D G3DSA:3.30.1310.20 55 116 6.3E-64 T 31-10-2018 N186_00645 0dd8e0506fab34e785dea845aa9f34e8 210 SUPERFAMILY SSF53271 1 208 4.06E-40 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like N186_08760 e14a742a806109560bed29a287878e57 284 Pfam PF11667 Putative zincin peptidase 54 150 5.2E-15 T 31-10-2018 IPR021683 Putative zincin peptidase N186_07640 5f0f738915600083d096d894e287c561 102 Gene3D G3DSA:2.40.50.970 1 90 1.8E-13 T 31-10-2018 IPR037254 HupF/HypC superfamily N186_07640 5f0f738915600083d096d894e287c561 102 Pfam PF01455 HupF/HypC family 1 67 2.1E-14 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC N186_07640 5f0f738915600083d096d894e287c561 102 SUPERFAMILY SSF159127 1 80 1.24E-13 T 31-10-2018 IPR037254 HupF/HypC superfamily N186_06865 dc430b7896f219718ac9342822c5ee4b 267 SUPERFAMILY SSF161098 7 263 1.12E-50 T 31-10-2018 IPR035906 MetI-like superfamily N186_06865 dc430b7896f219718ac9342822c5ee4b 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 262 1.5E-15 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_06865 dc430b7896f219718ac9342822c5ee4b 267 Gene3D G3DSA:1.10.3720.10 3 258 2.0E-47 T 31-10-2018 IPR035906 MetI-like superfamily N186_06210 e48fafb7495b04aee977cffc0dbf7c6a 196 Pfam PF02517 CAAX protease self-immunity 78 165 5.4E-5 T 31-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 N186_00105 12b312691f5a6260ffdfaed84f933bc0 620 SUPERFAMILY SSF53448 5 235 2.5E-29 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_00105 12b312691f5a6260ffdfaed84f933bc0 620 Pfam PF12804 MobA-like NTP transferase domain 5 123 2.4E-10 T 31-10-2018 IPR025877 MobA-like NTP transferase N186_00105 12b312691f5a6260ffdfaed84f933bc0 620 Gene3D G3DSA:3.90.550.10 4 236 3.7E-41 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases N186_01715 c3758f0207182a74d410c0af2abcfcd2 188 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 21 101 7.7E-9 T 31-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B N186_02495 a40aff8f0ed7dbccff7b0ebee696bcc2 68 Gene3D G3DSA:1.10.10.10 8 68 6.3E-15 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_02495 a40aff8f0ed7dbccff7b0ebee696bcc2 68 Pfam PF04255 Protein of unknown function (DUF433) 9 64 2.8E-22 T 31-10-2018 IPR007367 Protein of unknown function DUF433 N186_02495 a40aff8f0ed7dbccff7b0ebee696bcc2 68 SUPERFAMILY SSF46689 4 67 4.84E-18 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 N186_09685 0d9e799f07f61955ac7d4e9c083bcfde 243 Pfam PF04967 HTH DNA binding domain 173 224 7.1E-14 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain N186_02845 9df38246c4dc88ddd4dc20bebc9c27b7 168 Gene3D G3DSA:3.40.50.150 1 158 5.8E-49 T 31-10-2018 N186_02845 9df38246c4dc88ddd4dc20bebc9c27b7 168 SUPERFAMILY SSF53335 5 140 3.62E-30 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_02845 9df38246c4dc88ddd4dc20bebc9c27b7 168 Pfam PF13847 Methyltransferase domain 28 142 3.7E-8 T 31-10-2018 IPR025714 Methyltransferase domain N186_05035 9d8535ca42fd6dc07ac5b6984600a6e9 67 Pfam PF11781 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 19 48 4.1E-9 T 31-10-2018 IPR021752 Transcription initiation factor Rrn7, Zinc-finger Reactome: R-HSA-427359|Reactome: R-HSA-427413|Reactome: R-HSA-5250924|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73777|Reactome: R-HSA-73863 N186_09465 64d10f68a0b42c6e66548d82afeef283 290 Pfam PF02517 CAAX protease self-immunity 141 242 2.0E-11 T 31-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 N186_00340 a7a2cca47ad0ef4da9691ed4c114ad3e 337 Gene3D G3DSA:1.10.3720.10 100 327 2.2E-6 T 31-10-2018 IPR035906 MetI-like superfamily N186_00340 a7a2cca47ad0ef4da9691ed4c114ad3e 337 SUPERFAMILY SSF161098 109 319 4.9E-7 T 31-10-2018 IPR035906 MetI-like superfamily N186_00340 a7a2cca47ad0ef4da9691ed4c114ad3e 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 331 5.6E-34 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_02740 8662439bfaea1f428fffc1f6d34e94ff 421 Gene3D G3DSA:3.30.2010.10 230 305 3.9E-11 T 31-10-2018 N186_02740 8662439bfaea1f428fffc1f6d34e94ff 421 Pfam PF01435 Peptidase family M48 241 370 3.7E-9 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 N186_06125 859df27fe2b22a788534eaae93712ad3 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 251 9.0E-16 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_06125 859df27fe2b22a788534eaae93712ad3 258 SUPERFAMILY SSF161098 11 252 6.93E-44 T 31-10-2018 IPR035906 MetI-like superfamily N186_06125 859df27fe2b22a788534eaae93712ad3 258 Gene3D G3DSA:1.10.3720.10 10 255 5.1E-40 T 31-10-2018 IPR035906 MetI-like superfamily N186_08435 2ce8b261e70a93e5e9b6f1dd337f3319 281 Pfam PF03916 Polysulphide reductase, NrfD 6 277 2.2E-23 T 31-10-2018 IPR005614 NrfD family N186_08420 cb31ed446fcbf68b22e06e1640b5455b 476 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 3 462 4.2E-76 T 31-10-2018 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250 N186_08420 cb31ed446fcbf68b22e06e1640b5455b 476 Gene3D G3DSA:3.20.20.480 9 466 1.6E-126 T 31-10-2018 IPR038601 MttB-like superfamily KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250 N186_08590 bd8ba6d91859d9f7dd44225f353ca482 56 Pfam PF14471 Domain of unknown function (DUF4428) 5 39 1.4E-6 T 31-10-2018 IPR027872 Domain of unknown function DUF4428 N186_01925 68478648e527f85422b6c3ae7d4d74a8 179 SUPERFAMILY SSF143870 59 132 3.53E-8 T 31-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 N186_09715 884d9a0baba0d5818108334a3e3ab865 239 Gene3D G3DSA:3.30.470.20 20 230 5.2E-79 T 31-10-2018 N186_09715 884d9a0baba0d5818108334a3e3ab865 239 Pfam PF13549 ATP-grasp domain 12 232 3.1E-72 T 31-10-2018 N186_09715 884d9a0baba0d5818108334a3e3ab865 239 Gene3D G3DSA:3.30.1490.20 38 115 5.2E-79 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 N186_09715 884d9a0baba0d5818108334a3e3ab865 239 SUPERFAMILY SSF56059 21 235 1.94E-46 T 31-10-2018 N186_07665 12eb7c1bc01a06add0e84e53477b65a4 171 Gene3D G3DSA:3.60.15.10 10 167 2.6E-11 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_07665 12eb7c1bc01a06add0e84e53477b65a4 171 Pfam PF13483 Beta-lactamase superfamily domain 30 146 1.4E-9 T 31-10-2018 N186_07665 12eb7c1bc01a06add0e84e53477b65a4 171 SUPERFAMILY SSF56281 32 151 5.34E-6 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like N186_05745 1eaa1cf2b661b54bcc3dd1f49a6e876b 289 Pfam PF03547 Membrane transport protein 147 281 6.7E-14 T 31-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 N186_01915 fcc98fe64b24ed815c7da777529211b7 93 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 30 1.0E-8 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 N186_01915 fcc98fe64b24ed815c7da777529211b7 93 SUPERFAMILY SSF57783 1 34 7.48E-5 T 31-10-2018 N186_01915 fcc98fe64b24ed815c7da777529211b7 93 SMART SM00661 2 55 5.7E-10 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 N186_03615 e239ffc027b9dacf26764e91668df3cf 163 Pfam PF01930 Domain of unknown function DUF83 56 160 3.6E-14 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 N186_03615 e239ffc027b9dacf26764e91668df3cf 163 Gene3D G3DSA:3.90.320.10 1 163 3.5E-8 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal N186_03615 e239ffc027b9dacf26764e91668df3cf 163 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 2 161 5.1E-23 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 N186_06765 73f5544b1db906851bbf459baf98be85 281 SUPERFAMILY SSF46785 217 277 1.7E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_06765 73f5544b1db906851bbf459baf98be85 281 Gene3D G3DSA:1.10.10.10 218 280 6.0E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_06765 73f5544b1db906851bbf459baf98be85 281 Pfam PF13412 Winged helix-turn-helix DNA-binding 222 266 2.9E-6 T 31-10-2018 N186_01040 c665541a6594b26fdcfbb84d0a3ee04a 175 Pfam PF01928 CYTH domain 3 153 5.3E-32 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 N186_01040 c665541a6594b26fdcfbb84d0a3ee04a 175 Gene3D G3DSA:2.40.320.10 1 174 2.6E-42 T 31-10-2018 N186_01040 c665541a6594b26fdcfbb84d0a3ee04a 175 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 4 139 2.0E-24 T 31-10-2018 N186_01040 c665541a6594b26fdcfbb84d0a3ee04a 175 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 4 168 1.8E-35 T 31-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 N186_01040 c665541a6594b26fdcfbb84d0a3ee04a 175 SMART SM01118 2 171 7.8E-23 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 N186_01040 c665541a6594b26fdcfbb84d0a3ee04a 175 SUPERFAMILY SSF55154 3 168 1.05E-34 T 31-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 N186_09525 d13d8f4a1fef8d74e5267a70713db679 396 PRINTS PR01217 Proline rich extensin signature 126 143 7.5E-10 T 31-10-2018 N186_09525 d13d8f4a1fef8d74e5267a70713db679 396 PRINTS PR01217 Proline rich extensin signature 80 101 7.5E-10 T 31-10-2018 N186_09525 d13d8f4a1fef8d74e5267a70713db679 396 PRINTS PR01217 Proline rich extensin signature 109 125 7.5E-10 T 31-10-2018 N186_09525 d13d8f4a1fef8d74e5267a70713db679 396 PRINTS PR01217 Proline rich extensin signature 63 75 7.5E-10 T 31-10-2018 N186_09525 d13d8f4a1fef8d74e5267a70713db679 396 PRINTS PR01217 Proline rich extensin signature 43 59 7.5E-10 T 31-10-2018 N186_05415 d12c901e2e5887e2e307c65dd37a50df 293 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 149 155 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 N186_00085 466e01538b5059cf166aa0e32e0a0cda 233 Gene3D G3DSA:2.60.40.1120 108 181 4.6E-6 T 31-10-2018 N186_00085 466e01538b5059cf166aa0e32e0a0cda 233 SUPERFAMILY SSF49464 109 189 1.88E-5 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily N186_07100 da3c0c38dd8882dad72389da42b86e9c 386 Pfam PF05559 Protein of unknown function (DUF763) 4 340 1.3E-121 T 31-10-2018 IPR008482 Protein of unknown function DUF763 N186_06495 3d50193f167ffae46b285a2675ac63ca 228 SUPERFAMILY SSF53335 5 190 1.67E-25 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase N186_06495 3d50193f167ffae46b285a2675ac63ca 228 Gene3D G3DSA:3.40.50.150 2 194 2.0E-34 T 31-10-2018 N186_06495 3d50193f167ffae46b285a2675ac63ca 228 Pfam PF08241 Methyltransferase domain 49 138 4.9E-13 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 N186_04540 07f0ccf1abae6fac9b6318283f2f676b 736 Gene3D G3DSA:3.40.50.12610 508 606 6.1E-22 T 31-10-2018 N186_04540 07f0ccf1abae6fac9b6318283f2f676b 736 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 48 557 1.1E-38 T 31-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 N186_01250 c9a8b872f6df4a3ec12fe2965ae959ea 254 Pfam PF03703 Bacterial PH domain 141 196 1.5E-8 T 31-10-2018 IPR005182 Domain of unknown function DUF304 N186_01590 6759cd64f0bc9cac1b806cc79518626b 407 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 2 208 4.4E-15 T 31-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 N186_08700 1abea99fcbb1394f07e7fe7d24fa2bd0 333 SMART SM00933 74 286 1.1E-23 T 31-10-2018 IPR018977 NurA domain N186_08700 1abea99fcbb1394f07e7fe7d24fa2bd0 333 Pfam PF09376 NurA domain 216 286 2.9E-5 T 31-10-2018 IPR018977 NurA domain N186_04255 9b675426a99403cbf268e231e173e51b 170 SUPERFAMILY SSF54197 1 156 1.25E-38 T 31-10-2018 IPR036265 HIT-like superfamily N186_04255 9b675426a99403cbf268e231e173e51b 170 Gene3D G3DSA:3.30.428.10 1 164 4.6E-52 T 31-10-2018 IPR036265 HIT-like superfamily N186_04255 9b675426a99403cbf268e231e173e51b 170 Pfam PF01230 HIT domain 38 128 2.7E-14 T 31-10-2018 IPR001310 Histidine triad (HIT) protein N186_06715 ebf034b51730ba69d3f219aaa1b818cb 429 Pfam PF03611 PTS system sugar-specific permease component 13 402 3.0E-101 T 31-10-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 N186_04815 ac5acec6328b710f569a498a388bc8de 59 SUPERFAMILY SSF161187 12 52 8.24E-5 T 31-10-2018 N186_03680 55e65a90bbf5cb03b6ee0630fb1ccf9b 586 SUPERFAMILY SSF52540 192 488 4.32E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_03680 55e65a90bbf5cb03b6ee0630fb1ccf9b 586 SMART SM00382 207 466 0.001 T 31-10-2018 IPR003593 AAA+ ATPase domain N186_08775 cbb64d641ac0d4983d243a0a2d829391 310 SUPERFAMILY SSF64182 4 309 4.97E-36 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily N186_08775 cbb64d641ac0d4983d243a0a2d829391 310 Pfam PF02272 DHHA1 domain 199 309 1.0E-16 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 N186_08775 cbb64d641ac0d4983d243a0a2d829391 310 Gene3D G3DSA:3.10.310.30 229 310 8.9E-7 T 31-10-2018 N186_08920 16f2e4239ff8595a03dab22c85eedd8e 403 SUPERFAMILY SSF101960 12 392 1.57E-64 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily N186_08920 16f2e4239ff8595a03dab22c85eedd8e 403 Pfam PF01458 Uncharacterized protein family (UPF0051) 151 374 4.5E-42 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 N186_08135 5e819bcffde1dfc8b2ebb1b49701a7b2 142 Gene3D G3DSA:1.20.120.330 30 142 2.6E-20 T 31-10-2018 N186_08135 5e819bcffde1dfc8b2ebb1b49701a7b2 142 Pfam PF05942 Archaeal PaREP1/PaREP8 family 30 132 1.5E-27 T 31-10-2018 IPR010268 Archaeal PaREP1 N186_09330 642f8966604378d727afde9676d90c69 352 SUPERFAMILY SSF161098 93 337 1.13E-14 T 31-10-2018 IPR035906 MetI-like superfamily N186_09330 642f8966604378d727afde9676d90c69 352 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 352 1.6E-37 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 N186_07430 913d342396910f8d5089dae3f621af11 445 Pfam PF01694 Rhomboid family 60 220 4.8E-37 T 31-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 N186_07430 913d342396910f8d5089dae3f621af11 445 Gene3D G3DSA:1.20.1540.10 10 228 4.1E-33 T 31-10-2018 IPR035952 Rhomboid-like superfamily N186_07430 913d342396910f8d5089dae3f621af11 445 SUPERFAMILY SSF144091 17 217 3.01E-39 T 31-10-2018 N186_08910 ef366c9cf94fe59127400b591cc23f59 381 SUPERFAMILY SSF103473 6 378 2.88E-44 T 31-10-2018 IPR036259 MFS transporter superfamily N186_08910 ef366c9cf94fe59127400b591cc23f59 381 Gene3D G3DSA:1.20.1250.20 5 193 3.3E-23 T 31-10-2018 N186_08910 ef366c9cf94fe59127400b591cc23f59 381 Pfam PF07690 Major Facilitator Superfamily 19 331 1.2E-24 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_08910 ef366c9cf94fe59127400b591cc23f59 381 Gene3D G3DSA:1.20.1250.20 194 381 1.9E-15 T 31-10-2018 N186_01235 90a801929380e5b8eb7a03b6e3526a74 235 Gene3D G3DSA:3.40.50.1580 3 233 1.3E-58 T 31-10-2018 N186_01235 90a801929380e5b8eb7a03b6e3526a74 235 Pfam PF01048 Phosphorylase superfamily 12 199 1.3E-33 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 N186_01235 90a801929380e5b8eb7a03b6e3526a74 235 SUPERFAMILY SSF53167 4 229 1.57E-57 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 N186_07545 73565bd89ce767df0087502027e0657a 500 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 0.0017 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal N186_07805 a29135d4ccfacc2095718372d84b0032 210 SUPERFAMILY SSF51556 3 208 1.84E-35 T 31-10-2018 IPR032466 Metal-dependent hydrolase N186_07805 a29135d4ccfacc2095718372d84b0032 210 Pfam PF04909 Amidohydrolase 3 206 3.3E-31 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 N186_07805 a29135d4ccfacc2095718372d84b0032 210 Gene3D G3DSA:3.20.20.140 1 209 1.3E-40 T 31-10-2018 N186_07660 1486fc0d73c512efee3dc0cd6e2f245f 71 SUPERFAMILY SSF81593 7 66 6.28E-6 T 31-10-2018 N186_07660 1486fc0d73c512efee3dc0cd6e2f245f 71 Pfam PF01934 Protein of unknown function DUF86 20 65 3.7E-8 T 31-10-2018 IPR008201 Protein of unknown function DUF86 N186_07505 ed44af74654bc381d4208c020dc0d99b 291 SUPERFAMILY SSF47240 9 131 2.0E-11 T 31-10-2018 IPR009078 Ferritin-like superfamily N186_07095 f876341ccbc7f1e89e91cc1e2c568d4b 530 Pfam PF01943 Polysaccharide biosynthesis protein 14 289 8.3E-29 T 31-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 N186_07255 a6bad6a1cdfd9719dbfd7524118baa34 80 SUPERFAMILY SSF89447 1 47 5.1E-8 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily N186_07255 a6bad6a1cdfd9719dbfd7524118baa34 80 SMART SM00966 4 46 6.0E-4 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 N186_08685 b8523147d67f835d3f5cc7649673ad6d 138 SUPERFAMILY SSF88723 2 126 9.53E-17 T 31-10-2018 IPR029060 PIN-like domain superfamily N186_08685 b8523147d67f835d3f5cc7649673ad6d 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 131 9.507 T 31-10-2018 IPR022907 VapC family GO:0004540 N186_08685 b8523147d67f835d3f5cc7649673ad6d 138 Pfam PF01850 PIN domain 3 120 3.6E-9 T 31-10-2018 IPR002716 PIN domain N186_08685 b8523147d67f835d3f5cc7649673ad6d 138 Gene3D G3DSA:3.40.50.1010 1 129 2.0E-29 T 31-10-2018 N186_03585 e362f08ce928c5275206bf061e31e1f9 89 Gene3D G3DSA:3.30.310.50 4 85 7.9E-15 T 31-10-2018 N186_01380 496ce462b32f73c953545e4d69c02835 141 Pfam PF09921 Uncharacterized protein conserved in archaea (DUF2153) 15 135 5.1E-50 T 31-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 N186_06810 7dde2b59e46b02ffbcdd6ebe043be811 144 Pfam PF03916 Polysulphide reductase, NrfD 7 138 4.9E-12 T 31-10-2018 IPR005614 NrfD family N186_07550 64bc07aeab45b3091ca67f561421fb20 203 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 193 1.8E-36 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 N186_07550 64bc07aeab45b3091ca67f561421fb20 203 Pfam PF01914 MarC family integral membrane protein 14 198 6.8E-41 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 N186_00510 b351cb4bce5efd4e97af70d1e4028722 633 Gene3D G3DSA:3.30.230.10 33 240 1.0E-25 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup N186_00510 b351cb4bce5efd4e97af70d1e4028722 633 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 100 180 4.1E-14 T 31-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 N186_00510 b351cb4bce5efd4e97af70d1e4028722 633 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 145 164 2.5E-7 T 31-10-2018 N186_00510 b351cb4bce5efd4e97af70d1e4028722 633 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 115 134 2.5E-7 T 31-10-2018 N186_00510 b351cb4bce5efd4e97af70d1e4028722 633 SUPERFAMILY SSF54211 44 238 5.69E-28 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold N186_00435 b04041cdfaec51e55ce24201f4695f43 515 Pfam PF00343 Carbohydrate phosphorylase 282 457 7.8E-16 T 31-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 N186_00435 b04041cdfaec51e55ce24201f4695f43 515 SUPERFAMILY SSF53756 11 512 6.6E-88 T 31-10-2018 N186_00435 b04041cdfaec51e55ce24201f4695f43 515 Gene3D G3DSA:3.40.50.2000 254 510 4.0E-31 T 31-10-2018 N186_03085 679c422b7122fdf16cbfed0bd118fe2e 323 Pfam PF00953 Glycosyl transferase family 4 66 225 1.4E-29 T 31-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 N186_08600 8153f7234d64740d6059eed20f4f2572 408 SUPERFAMILY SSF52540 14 144 1.34E-6 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01685 4663fa72948d2bdce531d776b0dbd669 204 SUPERFAMILY SSF52980 4 112 1.39E-14 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 N186_01685 4663fa72948d2bdce531d776b0dbd669 204 Gene3D G3DSA:3.40.1350.10 8 119 5.3E-5 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 N186_08545 fe6a4d4d3ca1742b6deb8021e5ac5f7c 393 Pfam PF12704 MacB-like periplasmic core domain 24 239 9.6E-16 T 31-10-2018 IPR025857 MacB-like periplasmic core domain N186_08545 fe6a4d4d3ca1742b6deb8021e5ac5f7c 393 Pfam PF02687 FtsX-like permease family 296 385 4.0E-10 T 31-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 N186_04245 ff2830bdf74c4635d34063cc1c268b72 600 SUPERFAMILY SSF46785 1 54 1.46E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_04245 ff2830bdf74c4635d34063cc1c268b72 600 Pfam PF01022 Bacterial regulatory protein, arsR family 1 32 1.6E-4 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 N186_04245 ff2830bdf74c4635d34063cc1c268b72 600 Gene3D G3DSA:1.10.10.10 1 57 1.3E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_05870 b28cec61d2f8c3ab96f2cdd132ec7bb1 305 Gene3D G3DSA:1.10.472.100 211 304 1.7E-10 T 31-10-2018 N186_05870 b28cec61d2f8c3ab96f2cdd132ec7bb1 305 Pfam PF01080 Presenilin 224 300 3.4E-9 T 31-10-2018 IPR001108 Peptidase A22A, presenilin GO:0004190|GO:0016021|GO:0016485 Reactome: R-HSA-1251985|Reactome: R-HSA-193692|Reactome: R-HSA-205043|Reactome: R-HSA-2122948|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3928665|Reactome: R-HSA-9013507|Reactome: R-HSA-9013700|Reactome: R-HSA-9017802 N186_01620 c6bf4994b271297c0aee4feded82ecf7 196 Pfam PF04250 Protein of unknown function (DUF429) 6 161 1.0E-10 T 31-10-2018 IPR007362 Protein of unknown function DUF429 N186_06575 f436749ed29303f9efa380eae8b2addf 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 13 97 9.3E-6 T 31-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like N186_09655 6044f4470428f984adda88905a3349ac 268 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 258 1.8E-28 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 N186_06140 0509389936142c112bebc731dd71fc1b 354 Gene3D G3DSA:3.40.109.10 178 353 2.8E-32 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 N186_06140 0509389936142c112bebc731dd71fc1b 354 Gene3D G3DSA:3.40.109.10 28 149 5.5E-16 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 N186_06140 0509389936142c112bebc731dd71fc1b 354 SUPERFAMILY SSF55469 188 354 2.84E-17 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 N186_06140 0509389936142c112bebc731dd71fc1b 354 Pfam PF00881 Nitroreductase family 300 351 1.3E-6 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 N186_07555 dc0b9133d3e09f9e1090ae65f467de30 490 Pfam PF07690 Major Facilitator Superfamily 17 408 1.5E-44 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 N186_07555 dc0b9133d3e09f9e1090ae65f467de30 490 SUPERFAMILY SSF103473 3 473 8.76E-59 T 31-10-2018 IPR036259 MFS transporter superfamily N186_07555 dc0b9133d3e09f9e1090ae65f467de30 490 Gene3D G3DSA:1.20.1720.10 13 253 7.4E-36 T 31-10-2018 N186_00005 d2cef0ee9c2c1904c30394c56ccf73ac 152 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 2 140 1.1E-20 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 N186_00005 d2cef0ee9c2c1904c30394c56ccf73ac 152 Gene3D G3DSA:3.40.920.10 2 145 1.2E-5 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 N186_09025 e40ed72f8812c2b8b63584c63f61a8cd 133 Gene3D G3DSA:1.10.10.10 8 71 5.0E-13 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily N186_09025 e40ed72f8812c2b8b63584c63f61a8cd 133 SUPERFAMILY SSF46785 9 67 5.39E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily N186_09025 e40ed72f8812c2b8b63584c63f61a8cd 133 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 55 5.8E-11 T 31-10-2018 N186_07220 98baafcd13cecbad16ac0a9a1be7b94e 146 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 8 29 1.4E-4 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal N186_02045 dcd4d9ee2ded98dc15a769ccc4dc89e1 485 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 25 184 2.0E-11 T 31-10-2018 IPR007522 CRISPR-associated protein TM1795 N186_03490 b0e5b7713b48e8b48435c40930542e97 602 Pfam PF00482 Type II secretion system (T2SS), protein F 124 249 1.4E-8 T 31-10-2018 IPR018076 Type II secretion system F domain N186_03490 b0e5b7713b48e8b48435c40930542e97 602 Pfam PF00482 Type II secretion system (T2SS), protein F 398 524 6.7E-13 T 31-10-2018 IPR018076 Type II secretion system F domain N186_03570 5115f1e0df42c033fd03b35beb54b7ee 203 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 9 192 1.2E-33 T 31-10-2018 IPR019202 Protein of unknown function DUF2067 N186_08415 1d55fefe33c130c44f7a333abc8f5e09 79 SUPERFAMILY SSF47598 3 37 2.5E-5 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 N186_05145 26001f06b656517a3a2e2e2eacd1cc13 328 SUPERFAMILY SSF102114 117 256 1.96E-8 T 31-10-2018 N186_05145 26001f06b656517a3a2e2e2eacd1cc13 328 Gene3D G3DSA:3.20.20.70 16 300 1.1E-5 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 N186_08285 ef5bc2c2e67d183fc0d693859d214802 189 Pfam PF07155 ECF-type riboflavin transporter, S component 12 180 1.1E-33 T 31-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 N186_08285 ef5bc2c2e67d183fc0d693859d214802 189 Gene3D G3DSA:1.10.1760.20 2 185 5.0E-21 T 31-10-2018 N186_07890 747b6d71b8e46f21602c1770e2bddab2 372 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 27 320 1.2E-18 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 N186_07890 747b6d71b8e46f21602c1770e2bddab2 372 SUPERFAMILY SSF52540 5 322 1.41E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_07890 747b6d71b8e46f21602c1770e2bddab2 372 Gene3D G3DSA:3.40.50.300 4 329 4.9E-26 T 31-10-2018 N186_06925 fa63e3d05fa7731ce5cfd1a67e46e4bb 254 Gene3D G3DSA:3.20.20.60 4 254 2.6E-75 T 31-10-2018 N186_06925 fa63e3d05fa7731ce5cfd1a67e46e4bb 254 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 17 234 7.5E-39 T 31-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 N186_06925 fa63e3d05fa7731ce5cfd1a67e46e4bb 254 SUPERFAMILY SSF51621 4 247 1.22E-66 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 N186_01455 ccf4c99657f38d38fe77187019a1bcf8 156 Pfam PF02577 Bifunctional nuclease 29 147 1.3E-33 T 31-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 N186_01455 ccf4c99657f38d38fe77187019a1bcf8 156 Gene3D G3DSA:3.10.690.10 4 154 1.2E-37 T 31-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 N186_01455 ccf4c99657f38d38fe77187019a1bcf8 156 SUPERFAMILY SSF103256 34 144 2.22E-31 T 31-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 N186_09490 29c2864c70750c57fabe86774c0413cc 432 SUPERFAMILY SSF52540 14 153 5.73E-9 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase N186_01755 f51d65c6b34d9f3531e971bb62cea4ea 420 Pfam PF01882 Protein of unknown function DUF58 205 275 4.2E-9 T 31-10-2018 IPR002881 Domain of unknown function DUF58 N186_09720 ca2700565ea45497cd5e1ed569f65be0 120 Pfam PF13298 DNA polymerase Ligase (LigD) 9 108 8.3E-28 T 31-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain N186_06010 785bb43e7ff4e26add4f9deb92636826 142 Pfam PF01986 Domain of unknown function DUF123 20 111 3.8E-26 T 31-10-2018 IPR002837 Protein of unknown function DUF123 N186_02770 5e8deebaf4f6d9b07e87a1c53b207795 115 Gene3D G3DSA:2.40.50.140 1 114 4.7E-11 T 31-10-2018 N186_03590 b2edeb81d06cef92f1b11f345cc27b0b 175 Gene3D G3DSA:3.40.50.10480 1 162 1.2E-20 T 31-10-2018 N186_03590 b2edeb81d06cef92f1b11f345cc27b0b 175 SUPERFAMILY SSF52954 2 164 4.22E-15 T 31-10-2018 N186_03090 5f7a4f0472e97368878137dfb98a3f4b 331 Gene3D G3DSA:3.40.910.10 5 330 8.8E-78 T 31-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 N186_03090 5f7a4f0472e97368878137dfb98a3f4b 331 SUPERFAMILY SSF52467 11 327 2.29E-83 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily N186_03090 5f7a4f0472e97368878137dfb98a3f4b 331 Pfam PF01916 Deoxyhypusine synthase 32 322 1.4E-86 T 31-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 N186_05090 f39551ee9d875f9ca88f98a4fe563107 180 Gene3D G3DSA:3.40.50.300 3 174 3.1E-6 T 31-10-2018 N186_06740 f168284d04625d30d591176f1a8dfeed 270 Pfam PF02361 Cobalt transport protein 16 237 2.4E-26 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component N186_09595 3900c182ec1e6f422a9e474e411e41ad 190 Gene3D G3DSA:1.10.490.10 15 150 1.1E-7 T 31-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 N186_09595 3900c182ec1e6f422a9e474e411e41ad 190 Pfam PF11563 Protoglobin 17 139 6.1E-6 T 31-10-2018 N186_05805 d5040cf94134c055fb280aef31fccd9f 309 SUPERFAMILY SSF64182 2 307 1.83E-15 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily N186_00715 6ea5aafe6c09ec7485700b0da76d1196 83 Gene3D G3DSA:1.10.599.10 10 80 6.4E-6 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 N186_03120 d7ac5e3e1fc0eb74f9bb57a2cecc2bf8 56 SUPERFAMILY SSF47598 7 51 8.89E-6 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 N186_00580 1e2979a8ec546b821a4f275da6ce1f66 133 Pfam PF07849 Protein of unknown function (DUF1641) 94 129 4.2E-18 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 N186_04665 ecf8bc9131528b0ed3764d153ce5a464 361 Pfam PF04123 Domain of unknown function (DUF373) 11 348 1.2E-90 T 31-10-2018 IPR007254 Protein of unknown function DUF373 N186_05495 9f3454c697c030afab746bce0827092b 396 Pfam PF04412 Protein of unknown function (DUF521) 1 381 8.0E-129 T 31-10-2018 IPR007506 Aconitase X catalytic domain, putative N186_07500 6151330f5dd7b3258c89237e3d59cefe 145 Pfam PF03692 Putative zinc- or iron-chelating domain 19 104 3.3E-16 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein N186_07190 37bc01f15e90467abe43a34e042d8f13 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 313 1.9E-44 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 N186_03650 3e60d06a6833ef846e5184b8cc611b3a 110 Gene3D G3DSA:1.20.120.1610 3 98 1.2E-6 T 31-10-2018 N186_00550 c410e40077b6af3a4e82549ed089834f 95 Pfam PF03477 ATP cone domain 4 71 1.3E-11 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 N186_07905 8be376a3073aeeab11adaed835136cc1 49 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 1.4E-17 T 31-10-2018 IPR019270 Protein of unknown function DUF2283 N186_08690 24834ab75681b1f69377a3b9bf7e1a98 123 Pfam PF07362 Post-segregation antitoxin CcdA 52 88 8.9E-7 T 31-10-2018 IPR009956 Post-segregation antitoxin CcdA N186_08155 e0a981091a04ec42b62a631d293c4464 80 Pfam PF10049 Protein of unknown function (DUF2283) 2 51 1.9E-17 T 31-10-2018 IPR019270 Protein of unknown function DUF2283 N186_09385 ad0d93413fd2e839533ec79523db85fb 527 Gene3D G3DSA:3.10.620.30 227 328 2.1E-5 T 31-10-2018 N186_08740 ba061477d8da833c3c069529ce8a27ac 394 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 231 6.2E-24 T 31-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 N186_08790 14d9770ded9ccad7b7524dabf15f8f74 266 Pfam PF01040 UbiA prenyltransferase family 24 239 2.5E-16 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 N186_05225 ecba47d8895ac4e600301fef3105f973 202 Pfam PF06197 Protein of unknown function (DUF998) 22 190 2.3E-22 T 31-10-2018 IPR009339 Protein of unknown function DUF998 N186_07530 ad4e8bb66b4957b411b1595d8e8e77da 396 SUPERFAMILY SSF56747 61 244 1.98E-11 T 31-10-2018 N186_03110 9d46fda8b7855af6ad904a9790ed49db 162 Pfam PF09895 RecB-family nuclease (DUF2122) 40 151 9.0E-27 T 31-10-2018 IPR018665 Protein of unknown function DUF2122, RecB-family nuclease-related N186_09395 173758ba9ab3963b072a8cbac8843955 404 SUPERFAMILY SSF53743 40 278 1.57E-26 T 31-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 N186_00560 bd5a93428d7143c95bb7f4ecbe88b285 220 Pfam PF13197 Protein of unknown function (DUF4013) 32 193 7.6E-21 T 31-10-2018 IPR025098 Protein of unknown function DUF4013 N186_06815 06bfc56f1f1712602b203596ee574088 282 Pfam PF01925 Sulfite exporter TauE/SafE 33 271 2.2E-49 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 N186_05050 7326fc36b47888595d99f8b10b519d60 661 Pfam PF04312 Protein of unknown function (DUF460) 221 364 2.0E-44 T 31-10-2018 IPR007408 Protein of unknown function DUF460 N186_09275 c94b5cbbe5ca70acb6e79e1dbe0ef696 109 Pfam PF00939 Sodium:sulfate symporter transmembrane region 11 101 3.9E-23 T 31-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 N186_08990 47b4a0561ea2092ee55c370e39ef4754 103 Pfam PF12679 ABC-2 family transporter protein 1 99 3.7E-8 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 N186_09290 4a38bd1178d6ef6e0d736394110ba69f 74 Pfam PF07362 Post-segregation antitoxin CcdA 7 62 5.9E-5 T 31-10-2018 IPR009956 Post-segregation antitoxin CcdA N186_04915 e400ca6748b1fb62b620ad9c6973f6ec 243 Pfam PF02361 Cobalt transport protein 16 207 9.9E-26 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component N186_07370 5b7e152bcf6dd939bc619be159ec5b0d 75 Pfam PF02697 Putative antitoxin 6 72 5.1E-8 T 31-10-2018 IPR003847 Putative antitoxin N186_09055 316b0d4c855c097639447bc72a5cd3a9 281 Pfam PF02361 Cobalt transport protein 17 230 5.0E-28 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component