locus-tag	class	description
TCARB_0003	COG0585	pseudouridine synthase activity
TCARB_0004	COG1444	tRNA N-acetyltransferase activity
TCARB_0006	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TCARB_0021	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TCARB_0023	COG0175	sulfate reduction
TCARB_0035	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TCARB_0040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TCARB_0044	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TCARB_0045	COG1122	ATPase activity
TCARB_0046	COG1122	ATPase activity
TCARB_0047	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TCARB_0050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TCARB_0058	COG1192	Involved in chromosome partitioning
TCARB_0071	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
TCARB_0085	COG2078	PFAM AMMECR1 domain protein
TCARB_0087	COG1793	dna ligase
TCARB_0091	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TCARB_0096	COG0517	IMP dehydrogenase activity
TCARB_0096	COG0516	GMP reductase activity
TCARB_0098	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TCARB_0098	COG0519	Catalyzes the synthesis of GMP from XMP
TCARB_0102	COG1254	Belongs to the acylphosphatase family
TCARB_0104	COG0303	'Molybdopterin
TCARB_0105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TCARB_0108	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TCARB_0112	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TCARB_0115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TCARB_0116	COG2814	Major facilitator Superfamily
TCARB_0120	COG0310	cobalt ion transport
TCARB_0123	COG0109	protoheme IX farnesyltransferase activity
TCARB_0131	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TCARB_0132	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TCARB_0134	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TCARB_0137	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TCARB_0143	COG0126	phosphoglycerate kinase activity
TCARB_0149	COG1574	metal-dependent hydrolase with the TIM-barrel fold
TCARB_0164	COG1573	uracil-dna glycosylase
TCARB_0172	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TCARB_0177	COG2835	tetraacyldisaccharide 4'-kinase activity
TCARB_0178	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TCARB_0184	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TCARB_0186	COG0438	transferase activity, transferring glycosyl groups
TCARB_0187	COG1449	Belongs to the glycosyl hydrolase 57 family
TCARB_0188	COG0442	prolyl-tRNA aminoacylation
TCARB_0189	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
TCARB_0190	COG1234	tRNA 3'-trailer cleavage
TCARB_0191	COG1082	Xylose isomerase domain protein TIM barrel
TCARB_0192	COG1063	alcohol dehydrogenase
TCARB_0193	COG1402	creatininase
TCARB_0194	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TCARB_0195	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TCARB_0197	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TCARB_0198	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TCARB_0203	COG0330	HflC and HflK could
TCARB_0208	COG1830	Aldolase
TCARB_0213	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TCARB_0215	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TCARB_0218	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TCARB_0220	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TCARB_0224	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TCARB_0224	COG0551	DNA topoisomerase type I activity
TCARB_0229	COG0149	triose-phosphate isomerase activity
TCARB_0239	COG2151	metal-sulfur cluster biosynthetic enzyme
TCARB_0242	COG2255	four-way junction helicase activity
TCARB_0248	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TCARB_0250	COG0513	Belongs to the DEAD box helicase family
TCARB_0251	COG2264	protein methyltransferase activity
TCARB_0252	COG0017	Asparaginyl-tRNA synthetase
TCARB_0256	COG2814	Major facilitator Superfamily
TCARB_0258	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
TCARB_0262	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TCARB_0262	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCARB_0270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TCARB_0273	COG1940	carbohydrate kinase activity
TCARB_0276	COG0215	cysteine-tRNA ligase activity
TCARB_0277	COG1454	alcohol dehydrogenase
TCARB_0278	COG1126	abc transporter atp-binding protein
TCARB_0282	COG0489	protein tyrosine kinase activity
TCARB_0284	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TCARB_0285	COG1177	transmembrane transport
TCARB_0286	COG1176	ABC-type spermidine putrescine transport system, permease component I
TCARB_0287	COG3842	ATPase activity
TCARB_0290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TCARB_0298	COG0037	tRNA processing
TCARB_0306	COG1201	RNA secondary structure unwinding
TCARB_0322	COG1918	ferrous iron import across plasma membrane
TCARB_0322	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TCARB_0328	COG0656	L-ascorbic acid biosynthetic process
TCARB_0332	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TCARB_0334	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TCARB_0338	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TCARB_0344	COG1487	ribonuclease activity
TCARB_0351	COG0673	inositol 2-dehydrogenase activity
TCARB_0352	COG1201	RNA secondary structure unwinding
TCARB_0363	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TCARB_0364	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TCARB_0379	COG0456	acetyltransferase
TCARB_0381	COG3260	NADH ubiquinone oxidoreductase 20
TCARB_0382	COG3261	NADH dehydrogenase
TCARB_0382	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TCARB_0384	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TCARB_0387	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TCARB_0388	COG0651	ATP synthesis coupled electron transport
TCARB_0390	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_0391	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_0392	COG0649	NAD binding
TCARB_0393	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TCARB_0394	COG4656	Part of a membrane complex involved in electron transport
TCARB_0396	COG0713	ATP synthesis coupled electron transport
TCARB_0397	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_0398	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TCARB_0399	COG1007	ATP synthesis coupled electron transport
TCARB_0400	COG0174	glutamine synthetase
TCARB_0401	COG0693	protein deglycase activity
TCARB_0402	COG4821	SIS domain
TCARB_0403	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TCARB_0407	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TCARB_0411	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
TCARB_0413	COG3716	PTS system mannose fructose sorbose family IID component
TCARB_0414	COG0561	phosphatase activity
TCARB_0415	COG3037	sugar-specific permease SgaT UlaA
TCARB_0417	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TCARB_0418	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TCARB_0421	COG1122	ATPase activity
TCARB_0424	COG2723	6-phospho-beta-galactosidase activity
TCARB_0426	COG1085	galactose-1-phosphate uridylyltransferase
TCARB_0433	COG0437	4 iron, 4 sulfur cluster binding
TCARB_0440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TCARB_0445	COG0395	ABC-type sugar transport system, permease component
TCARB_0446	COG3842	ATPase activity
TCARB_0448	COG2431	L-lysine efflux transmembrane transporter activity
TCARB_0457	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TCARB_0458	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TCARB_0459	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
TCARB_0460	COG3836	Belongs to the HpcH HpaI aldolase family
TCARB_0461	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TCARB_0462	COG1070	Carbohydrate kinase
TCARB_0466	COG1175	transmembrane transport
TCARB_0467	COG0395	ABC-type sugar transport system, permease component
TCARB_0468	COG1070	Carbohydrate kinase
TCARB_0471	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TCARB_0472	COG0540	Belongs to the ATCase OTCase family
TCARB_0473	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TCARB_0474	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TCARB_0475	COG0543	2 iron, 2 sulfur cluster binding
TCARB_0476	COG0167	dihydroorotate dehydrogenase activity
TCARB_0477	COG1418	mRNA catabolic process
TCARB_0480	COG3842	ATPase activity
TCARB_0484	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TCARB_0487	COG1131	(ABC) transporter
TCARB_0492	COG3833	ABC-type maltose transport systems, permease component
TCARB_0493	COG3842	ATPase activity
TCARB_0495	COG2095	MarC family integral membrane protein
TCARB_0498	COG0543	2 iron, 2 sulfur cluster binding
TCARB_0499	COG0493	'glutamate synthase
TCARB_0499	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TCARB_0505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TCARB_0517	COG0396	ATPase activity
TCARB_0521	COG4214	carbohydrate transport
TCARB_0532	COG0501	Belongs to the peptidase M48B family
TCARB_0536	COG1131	(ABC) transporter
TCARB_0542	COG0667	Aldo Keto reductase
TCARB_0543	COG1850	ribulose-bisphosphate carboxylase activity
TCARB_0545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCARB_0547	COG0371	Dehydrogenase
TCARB_0557	COG0864	Transcriptional regulator
TCARB_0560	COG0277	FAD linked oxidase domain protein
TCARB_0563	COG0446	pyridine nucleotide-disulphide oxidoreductase
TCARB_0563	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TCARB_0565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TCARB_0572	COG1175	transmembrane transport
TCARB_0573	COG3833	ABC-type maltose transport systems, permease component
TCARB_0574	COG3842	ATPase activity
TCARB_0575	COG1378	Sugar-specific transcriptional regulator TrmB
TCARB_0581	COG0778	Nitroreductase
TCARB_0584	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TCARB_0585	COG1830	Aldolase
TCARB_0586	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TCARB_0586	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TCARB_0587	COG0805	protein transport
TCARB_0589	COG0805	protein transport
TCARB_0590	COG0454	-acetyltransferase
TCARB_0592	COG2095	MarC family integral membrane protein
TCARB_0598	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TCARB_0599	COG0747	negative chemotaxis
TCARB_0600	COG0601	transmembrane transport
TCARB_0601	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TCARB_0602	COG0444	Belongs to the ABC transporter superfamily
TCARB_0603	COG4608	Belongs to the ABC transporter superfamily
TCARB_0606	COG0243	molybdopterin cofactor binding
TCARB_0614	COG0309	Hydrogenase expression formation protein (HypE)
TCARB_0618	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TCARB_0620	COG1342	Belongs to the UPF0251 family
TCARB_0628	COG2211	Major facilitator Superfamily
TCARB_0631	COG0586	Pfam SNARE associated Golgi protein
TCARB_0635	COG0668	transmembrane transport
TCARB_0642	COG0395	ABC-type sugar transport system, permease component
TCARB_0651	COG1598	PFAM Uncharacterised protein family UPF0150
TCARB_0653	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TCARB_0658	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TCARB_0673	COG1088	dTDP-glucose 4,6-dehydratase activity
TCARB_0674	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TCARB_0686	COG0438	transferase activity, transferring glycosyl groups
TCARB_0689	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TCARB_0690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TCARB_0697	COG1598	PFAM Uncharacterised protein family UPF0150
TCARB_0723	COG0438	transferase activity, transferring glycosyl groups
TCARB_0725	COG0489	protein tyrosine kinase activity
TCARB_0737	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TCARB_0749	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TCARB_0753	COG0395	ABC-type sugar transport system, permease component
TCARB_0766	COG5012	cobalamin binding
TCARB_0770	COG0243	molybdopterin cofactor binding
TCARB_0775	COG2267	carboxylic ester hydrolase activity
TCARB_0783	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TCARB_0786	COG1136	(ABC) transporter
TCARB_0787	COG1136	(ABC) transporter
TCARB_0787	COG0577	efflux transmembrane transporter activity
TCARB_0792	COG1131	(ABC) transporter
TCARB_0795	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TCARB_0809	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TCARB_0837	COG0438	transferase activity, transferring glycosyl groups
TCARB_0838	COG1378	Sugar-specific transcriptional regulator TrmB
TCARB_0839	COG1131	(ABC) transporter
TCARB_0840	COG0842	Transport permease protein
TCARB_0844	COG1063	alcohol dehydrogenase
TCARB_0847	COG0531	amino acid
TCARB_0849	COG1486	melibiose metabolic process
TCARB_0860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TCARB_0864	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
TCARB_0869	COG0437	4 iron, 4 sulfur cluster binding
TCARB_0870	COG1151	hydroxylamine reductase activity
TCARB_0873	COG2111	Na H antiporter
TCARB_0873	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TCARB_0874	COG0649	NAD binding
TCARB_0874	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_0875	COG0649	NAD binding
TCARB_0877	COG3260	NADH ubiquinone oxidoreductase 20
TCARB_0878	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TCARB_0879	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_0881	COG0534	Mate efflux family protein
TCARB_0886	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TCARB_0888	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TCARB_0891	COG4555	ABC transporter
TCARB_0893	COG4690	dipeptidase activity
TCARB_0902	COG2814	Major facilitator Superfamily
TCARB_0903	COG0402	S-adenosylhomocysteine deaminase activity
TCARB_0904	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
TCARB_0907	COG1122	ATPase activity
TCARB_0908	COG1122	ATPase activity
TCARB_0920	COG1028	Short-chain dehydrogenase reductase Sdr
TCARB_0927	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TCARB_0962	COG0471	metal ion transport
TCARB_0964	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TCARB_0978	COG1872	DUF167
TCARB_0979	COG4608	Belongs to the ABC transporter superfamily
TCARB_0980	COG0444	Belongs to the ABC transporter superfamily
TCARB_0982	COG0601	transmembrane transport
TCARB_0988	COG0698	ribose 5-phosphate isomerase
TCARB_0989	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TCARB_0993	COG1435	thymidine kinase activity
TCARB_0999	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
TCARB_1005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TCARB_1008	COG1575	Belongs to the MenA family. Type 1 subfamily
TCARB_1009	COG0535	radical SAM domain protein
TCARB_1011	COG1214	PFAM Peptidase M22, glycoprotease
TCARB_1011	COG0456	acetyltransferase
TCARB_1012	COG1058	Belongs to the CinA family
TCARB_1012	COG1546	Belongs to the CinA family
TCARB_1013	COG1309	transcriptional regulator
TCARB_1031	COG0450	alkyl hydroperoxide reductase
TCARB_1038	COG0419	ATPase involved in DNA repair
TCARB_1041	COG0730	response to heat
TCARB_1043	COG0411	ABC transporter
TCARB_1047	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TCARB_1049	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TCARB_1052	COG0410	ABC transporter
TCARB_1053	COG0411	ABC transporter
TCARB_1056	COG0318	PFAM AMP-dependent synthetase and ligase
TCARB_1058	COG1028	Short-chain dehydrogenase reductase Sdr
TCARB_1059	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TCARB_1062	COG0045	succinate-CoA ligase (ADP-forming) activity
TCARB_1062	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TCARB_1062	COG1042	CoA-binding domain protein
TCARB_1063	COG1042	CoA-binding domain protein
TCARB_1063	COG0045	succinate-CoA ligase (ADP-forming) activity
TCARB_1063	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TCARB_1064	COG3285	dna ligase
TCARB_1064	COG1793	dna ligase
TCARB_1071	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TCARB_1071	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCARB_1072	COG1013	pyruvate-flavodoxin oxidoreductase activity
TCARB_1074	COG0493	'glutamate synthase
TCARB_1082	COG0417	DNA replication proofreading
TCARB_1089	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TCARB_1089	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TCARB_1090	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TCARB_1092	COG1213	nucleotidyl transferase
TCARB_1092	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TCARB_1095	COG0235	Class ii aldolase
TCARB_1116	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TCARB_1121	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TCARB_1124	COG0301	tRNA thio-modification
TCARB_1124	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TCARB_1131	COG0494	nUDIX hydrolase
TCARB_1135	COG4221	oxidoreductase activity
TCARB_1144	COG1260	myo-inositol-1-phosphate synthase
TCARB_1145	COG4608	Belongs to the ABC transporter superfamily
TCARB_1148	COG0601	transmembrane transport
TCARB_1149	COG4166	transmembrane transport
TCARB_1168	COG4591	ABC-type transport system involved in lipoprotein release permease component
TCARB_1169	COG1136	(ABC) transporter
TCARB_1173	COG1063	alcohol dehydrogenase
TCARB_1174	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TCARB_1175	COG1840	ABC-type Fe3 transport system, periplasmic component
TCARB_1177	COG1177	transmembrane transport
TCARB_1178	COG3842	ATPase activity
TCARB_1179	COG0584	glycerophosphoryl diester phosphodiesterase
TCARB_1180	COG2094	Belongs to the DNA glycosylase MPG family
TCARB_1182	COG1067	ATP-dependent peptidase activity
TCARB_1182	COG0470	DNA polymerase III
TCARB_1185	COG4150	thiosulfate binding
TCARB_1189	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TCARB_1198	COG0425	Belongs to the sulfur carrier protein TusA family
TCARB_1201	COG3842	ATPase activity
TCARB_1208	COG0009	L-threonylcarbamoyladenylate synthase
TCARB_1211	COG0477	Major facilitator Superfamily
TCARB_1218	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TCARB_1220	COG2217	Heavy metal translocating P-type atpase
TCARB_1225	COG2414	aldehyde ferredoxin oxidoreductase
TCARB_1229	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TCARB_1230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TCARB_1240	COG2033	superoxide reductase activity
TCARB_1244	COG0017	Asparaginyl-tRNA synthetase
TCARB_1247	COG1528	Iron-storage protein
TCARB_1249	COG4948	Mandelate Racemase Muconate Lactonizing
TCARB_1251	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TCARB_1255	COG1363	Peptidase, m42
TCARB_1256	COG1592	Rubrerythrin
TCARB_1257	COG1522	sequence-specific DNA binding
TCARB_1262	COG2814	Major facilitator Superfamily
TCARB_1263	COG1122	ATPase activity
TCARB_1264	COG1122	ATPase activity
TCARB_1265	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TCARB_1268	COG0563	adenylate kinase activity
TCARB_1275	COG3613	nucleoside 2-deoxyribosyltransferase
TCARB_1276	COG1522	sequence-specific DNA binding
TCARB_1284	COG0436	Aminotransferase
TCARB_1300	COG0312	modulator of DNA gyrase
TCARB_1301	COG0312	modulator of DNA gyrase
TCARB_1313	COG0531	amino acid
TCARB_1331	COG0402	S-adenosylhomocysteine deaminase activity
TCARB_1332	COG0813	purine-nucleoside phosphorylase activity
TCARB_1334	COG0813	purine-nucleoside phosphorylase activity
TCARB_1336	COG4720	Psort location CytoplasmicMembrane, score
TCARB_1339	COG1122	ATPase activity
TCARB_1346	COG2084	Dehydrogenase
TCARB_1354	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TCARB_1361	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TCARB_1362	COG2414	aldehyde ferredoxin oxidoreductase
TCARB_1373	COG1535	isochorismatase
TCARB_1373	COG3433	isochorismatase activity
TCARB_1374	COG4974	Belongs to the 'phage' integrase family
TCARB_1378	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TCARB_1380	COG0148	phosphopyruvate hydratase activity
TCARB_1381	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TCARB_1386	COG0084	hydrolase, TatD family'
TCARB_1387	COG0439	Biotin carboxylase
TCARB_1388	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TCARB_1389	COG0803	Belongs to the bacterial solute-binding protein 9 family
TCARB_1394	COG0813	purine-nucleoside phosphorylase activity
TCARB_1398	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TCARB_1405	COG3276	selenocysteine insertion sequence binding
TCARB_1408	COG0717	Belongs to the dCTP deaminase family
TCARB_1412	COG0446	pyridine nucleotide-disulphide oxidoreductase
TCARB_1414	COG4608	Belongs to the ABC transporter superfamily
TCARB_1415	COG0444	Belongs to the ABC transporter superfamily
TCARB_1418	COG0747	negative chemotaxis
TCARB_1423	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TCARB_1426	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TCARB_1431	COG0003	Pfam Anion-transporting ATPase
TCARB_1434	COG0714	Associated with various cellular activities
TCARB_1437	COG0563	adenylate kinase activity
TCARB_1443	COG0549	Belongs to the carbamate kinase family
TCARB_1446	COG2414	aldehyde ferredoxin oxidoreductase
TCARB_1448	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TCARB_1450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TCARB_1450	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TCARB_1452	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TCARB_1463	COG2379	hydroxypyruvate reductase
TCARB_1467	COG0488	(ABC) transporter
TCARB_1471	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
TCARB_1472	COG0430	RNA-3'-phosphate cyclase activity
TCARB_1473	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TCARB_1475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TCARB_1477	COG0081	regulation of translation
TCARB_1478	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TCARB_1479	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TCARB_1480	COG1252	NADH dehydrogenase
TCARB_1481	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TCARB_1482	COG0089	rRNA binding
TCARB_1484	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TCARB_1493	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TCARB_1497	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TCARB_1499	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TCARB_1501	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TCARB_1503	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TCARB_1505	COG0006	proline dipeptidase activity
TCARB_1512	COG0436	Aminotransferase
TCARB_1516	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TCARB_1517	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TCARB_1518	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TCARB_1520	COG4948	Mandelate Racemase Muconate Lactonizing
TCARB_1523	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TCARB_1523	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TCARB_1524	COG2255	four-way junction helicase activity
TCARB_1525	COG0049	tRNA binding
TCARB_1530	COG1355	regulation of microtubule-based process
TCARB_1531	COG0052	Belongs to the universal ribosomal protein uS2 family
TCARB_1534	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TCARB_1535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TCARB_1540	COG1358	cellular component organization or biogenesis
TCARB_1541	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TCARB_1542	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TCARB_1543	COG0085	RNA polymerase activity
TCARB_1545	COG0423	glycine-tRNA ligase activity
TCARB_1547	COG0864	Transcriptional regulator
TCARB_1550	COG0459	protein refolding
TCARB_1553	COG1247	-acetyltransferase
TCARB_1557	COG0417	DNA replication proofreading
TCARB_1564	COG1598	PFAM Uncharacterised protein family UPF0150
TCARB_1573	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TCARB_1574	COG1047	Peptidyl-prolyl cis-trans
TCARB_1577	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TCARB_1578	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TCARB_1581	COG0521	Mo-molybdopterin cofactor biosynthetic process
TCARB_1585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TCARB_1586	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TCARB_1588	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TCARB_1589	COG2234	aminopeptidase activity
TCARB_1590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TCARB_1590	COG0301	tRNA thio-modification
TCARB_1595	COG0525	valine-tRNA ligase activity
TCARB_1597	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TCARB_1601	COG0469	pyruvate kinase activity
TCARB_1607	COG1328	CTP reductase activity
TCARB_1608	COG0045	succinate-CoA ligase (ADP-forming) activity
TCARB_1608	COG1042	CoA-binding domain protein
TCARB_1608	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TCARB_1609	COG1269	ATP hydrolysis coupled proton transport
TCARB_1614	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TCARB_1618	COG0501	Belongs to the peptidase M48B family
TCARB_1628	COG0343	queuine tRNA-ribosyltransferase activity
TCARB_1641	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TCARB_1644	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
TCARB_1649	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TCARB_1655	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TCARB_1656	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TCARB_1657	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TCARB_1662	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TCARB_1674	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TCARB_1677	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TCARB_1678	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TCARB_1681	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TCARB_1694	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TCARB_1695	COG1793	dna ligase
TCARB_1697	COG3276	selenocysteine insertion sequence binding
TCARB_1698	COG0457	Tetratricopeptide repeat
TCARB_1698	COG0552	protein localization to endoplasmic reticulum
TCARB_1709	COG1144	Oxidoreductase
TCARB_1710	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCARB_1711	COG1013	pyruvate-flavodoxin oxidoreductase activity
TCARB_1712	COG1110	DNA topoisomerase II activity
TCARB_1713	COG1056	cytidyltransferase-related domain
TCARB_1713	COG1051	belongs to the nudix hydrolase family
TCARB_1717	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TCARB_1741	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TCARB_1742	COG1522	sequence-specific DNA binding
TCARB_1743	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TCARB_1744	COG0255	Belongs to the universal ribosomal protein uL29 family
TCARB_1747	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TCARB_1755	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TCARB_1757	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCARB_1758	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TCARB_1761	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TCARB_1766	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TCARB_1768	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TCARB_1769	COG0528	UMP kinase activity
TCARB_1771	COG2264	protein methyltransferase activity
TCARB_1774	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TCARB_1775	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TCARB_1779	COG1192	Involved in chromosome partitioning
TCARB_1789	COG2226	methyltransferase
TCARB_1794	COG1773	rubredoxin
TCARB_1794	COG0426	domain, Protein
TCARB_1795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TCARB_1799	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TCARB_1804	COG1358	cellular component organization or biogenesis
TCARB_1805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TCARB_1805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TCARB_1808	COG1185	polyribonucleotide nucleotidyltransferase activity
TCARB_1810	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TCARB_1816	COG0419	ATPase involved in DNA repair
TCARB_1830	COG4152	abc transporter atp-binding protein
TCARB_1836	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TCARB_1863	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCARB_1864	COG1013	pyruvate-flavodoxin oxidoreductase activity
TCARB_1866	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TCARB_1872	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TCARB_1887	COG0495	leucyl-tRNA aminoacylation
TCARB_1889	COG0180	Tryptophanyl-tRNA synthetase
TCARB_1890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TCARB_1890	COG0574	Belongs to the PEP-utilizing enzyme family
TCARB_1891	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
TCARB_1894	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
TCARB_1897	COG0411	ABC transporter
TCARB_1898	COG0410	ABC transporter
TCARB_1899	COG0559	Belongs to the binding-protein-dependent transport system permease family
TCARB_1901	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TCARB_1901	COG1042	CoA-binding domain protein
TCARB_1901	COG0045	succinate-CoA ligase (ADP-forming) activity
TCARB_1902	COG0432	Pfam Uncharacterised protein family UPF0047
TCARB_1903	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TCARB_1906	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TCARB_1908	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TCARB_1910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TCARB_1912	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TCARB_1913	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCARB_1914	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TCARB_1915	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TCARB_1918	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TCARB_1918	COG1793	dna ligase
TCARB_1925	COG0017	Asparaginyl-tRNA synthetase
TCARB_1929	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TCARB_1938	COG1185	polyribonucleotide nucleotidyltransferase activity
TCARB_1941	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TCARB_1942	COG0051	transcription antitermination factor activity, RNA binding
TCARB_1946	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TCARB_1952	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TCARB_1953	COG0124	histidyl-tRNA synthetase
TCARB_1954	COG2222	sugar isomerase
TCARB_1958	COG1234	tRNA 3'-trailer cleavage
TCARB_1965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TCARB_1965	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TCARB_1966	COG1515	deoxyribonuclease V activity
TCARB_1968	COG0024	Methionine aminopeptidase