locus-tag	class	description
THTE_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
THTE_0004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THTE_0006	ENOG4107MVR	Transcriptional regulator
THTE_0008	ENOG4105CJ1	ABC, transporter
THTE_0009	ENOG4107QWP	ABC-2 type transporter
THTE_0010	ENOG4107QWP	ABC-2 type transporter
THTE_0011	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
THTE_0020	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THTE_0023	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
THTE_0030	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
THTE_0040	ENOG4108KS2	transglutaminase domain protein
THTE_0041	ENOG4105CN1	protease
THTE_0046	ENOG4105CP7	Triose-phosphate isomerase
THTE_0048	ENOG4105DSJ	YicC domain protein
THTE_0049	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
THTE_0050	ENOG41063B5	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
THTE_0051	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
THTE_0052	ENOG41062ES	Transcriptional regulator
THTE_0053	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
THTE_0055	ENOG4105DQU	oxidoreductase, subunit beta
THTE_0056	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
THTE_0057	ENOG4105CJW	magnesium transporter
THTE_0064	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
THTE_0068	ENOG4105CUT	histidyl-tRNA synthetase
THTE_0073	ENOG4105C01	Dihydroxy-acid dehydratase
THTE_0078	ENOG4105GYT	Protein of unknown function (DUF1009)
THTE_0079	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THTE_0082	ENOG4107XCC	Catalyzes the synthesis of activated sulfate (By similarity)
THTE_0084	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
THTE_0087	ENOG41061MV	Arylsulfatase
THTE_0088	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
THTE_0095	ENOG4105DKQ	ROK family
THTE_0096	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
THTE_0106	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
THTE_0110	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
THTE_0115	ENOG4105DC1	bifunctional purine biosynthesis protein purh
THTE_0128	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
THTE_0129	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
THTE_0130	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
THTE_0131	ENOG4105CE9	30S ribosomal protein S2
THTE_0144	ENOG4105CEY	Amp-dependent synthetase and ligase
THTE_0150	ENOG4105BZU	Histidine kinase
THTE_0153	ENOG4105CQ7	ATP-dependent helicase
THTE_0163	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
THTE_0171	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
THTE_0172	ENOG4107QR9	Iron-sulfur cluster binding protein
THTE_0173	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
THTE_0177	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
THTE_0182	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
THTE_0183	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
THTE_0187	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
THTE_0188	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
THTE_0193	ENOG4105K5M	30s ribosomal protein S16
THTE_0194	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
THTE_0195	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
THTE_0197	ENOG4105VFF	UPF0102 protein
THTE_0203	ENOG4105ENH	Sulfatase
THTE_0204	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
THTE_0205	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
THTE_0206	ENOG4105BZS	acriflavin resistance protein
THTE_0219	ENOG4107QW8	radical SAM domain protein
THTE_0223	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
THTE_0228	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
THTE_0242	ENOG4105DA5	(ABC) transporter
THTE_0245	ENOG4105CHV	Transcription elongation factor NusA
THTE_0247	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
THTE_0249	ENOG41082KD	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
THTE_0255	ENOG4105BZU	Histidine kinase
THTE_0256	ENOG4105C09	Bile acid
THTE_0258	ENOG4108JUA	Transcriptional regulator
THTE_0259	ENOG4107YR5	Diacylglycerol kinase
THTE_0262	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
THTE_0264	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
THTE_0265	ENOG4105PSV	Polysaccharide Biosynthesis Protein
THTE_0268	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THTE_0272	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
THTE_0273	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THTE_0274	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THTE_0275	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
THTE_0289	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
THTE_0295	ENOG4108ZP8	Acetolactate synthase small subunit
THTE_0296	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
THTE_0302	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THTE_0306	ENOG4105CE1	Ferrous iron transport protein b
THTE_0315	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
THTE_0321	ENOG4106855	Competence protein
THTE_0324	ENOG4107QHF	type ii secretion system protein e
THTE_0325	ENOG4105CZX	twitching motility protein
THTE_0326	ENOG4107QHF	type ii secretion system protein e
THTE_0330	ENOG410639E	50S ribosomal protein L33
THTE_0331	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
THTE_0337	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
THTE_0339	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
THTE_0345	ENOG4105CPF	Cell wall formation (By similarity)
THTE_0352	ENOG4105C5S	asparaginyl-tRNA synthetase
THTE_0353	ENOG4105C3M	thioredoxin reductase
THTE_0356	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
THTE_0359	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
THTE_0366	ENOG4105BZU	Histidine kinase
THTE_0368	ENOG4108V3W	Chemotaxis protein, CheW
THTE_0370	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
THTE_0374	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
THTE_0379	ENOG4105C0B	DNA polymerase III (alpha subunit)
THTE_0382	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
THTE_0387	ENOG4105QUH	Domain of unknown function (DUF2088)
THTE_0390	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
THTE_0405	ENOG4105G6Z	alkaline phosphatase
THTE_0424	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
THTE_0426	ENOG4105C01	Dihydroxy-acid dehydratase
THTE_0432	ENOG4105HEE	Binding Domain protein
THTE_0437	ENOG4105C1Q	protoporphyrinogen oxidase
THTE_0447	ENOG410855V	Acylphosphatase
THTE_0454	ENOG4105BZU	Histidine kinase
THTE_0455	ENOG4105CTX	dehydratase
THTE_0460	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
THTE_0465	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
THTE_0468	ENOG4105CFH	Aspartokinase
THTE_0470	ENOG4105E3H	phosphoglycerate mutase
THTE_0471	ENOG4105D6E	homoserine dehydrogenase
THTE_0476	ENOG4105D9P	serine threonine protein kinase
THTE_0482	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THTE_0484	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
THTE_0485	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
THTE_0491	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
THTE_0492	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
THTE_0498	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THTE_0500	ENOG4105CM2	brancheD-chain amino acid aminotransferase
THTE_0503	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
THTE_0507	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THTE_0521	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
THTE_0523	ENOG4105C0H	protease
THTE_0526	ENOG4105FDK	ABC transporter
THTE_0542	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
THTE_0544	ENOG4105C0H	protease
THTE_0555	ENOG41081EM	Involved in DNA repair and RecF pathway recombination (By similarity)
THTE_0556	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
THTE_0557	ENOG4105C3F	Signal peptidase i
THTE_0561	ENOG4107QHQ	amino acid
THTE_0564	ENOG4105D9P	serine threonine protein kinase
THTE_0572	ENOG4108UM1	dedA family
THTE_0574	ENOG4107QYG	anthranilate phosphoribosyltransferase
THTE_0579	ENOG4105BZU	Histidine kinase
THTE_0580	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
THTE_0582	ENOG4105MAX	Superoxide reductase
THTE_0588	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
THTE_0596	ENOG4105E6M	Sulphatase-modifying factor protein
THTE_0598	ENOG4105CMG	Carbohydrate kinase
THTE_0601	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
THTE_0612	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
THTE_0615	ENOG4108YXG	UPF0502 protein
THTE_0623	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
THTE_0624	ENOG4105C8N	cysteinyl-tRNA synthetase
THTE_0625	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
THTE_0628	ENOG4105K78	MarR family Transcriptional regulator
THTE_0633	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
THTE_0637	ENOG4107QHF	type ii secretion system protein e
THTE_0638	ENOG4105CZX	twitching motility protein
THTE_0639	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
THTE_0640	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
THTE_0647	ENOG4108UJU	UPF0301 protein
THTE_0650	ENOG4105CY3	ABC transporter, permease
THTE_0664	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
THTE_0672	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
THTE_0673	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
THTE_0678	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
THTE_0679	ENOG4107RIQ	Sulfate adenylate transferase
THTE_0683	ENOG4108IAJ	Nad-dependent epimerase dehydratase
THTE_0685	ENOG4105BZU	Histidine kinase
THTE_0689	ENOG4105EYW	Ion transport protein
THTE_0696	ENOG4108HKT	sucrose-6-phosphate hydrolase
THTE_0697	ENOG4107RA4	Glycosyl transferase (Group 1
THTE_0704	ENOG4105BZU	Histidine kinase
THTE_0705	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
THTE_0707	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
THTE_0708	ENOG410820W	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
THTE_0711	ENOG4105F8J	Adenylate Guanylate cyclase
THTE_0722	ENOG41076HS	cation diffusion facilitator family transporter
THTE_0726	ENOG4105C0H	protease
THTE_0728	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
THTE_0729	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
THTE_0730	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
THTE_0734	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
THTE_0738	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
THTE_0740	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
THTE_0756	ENOG4105M6F	mutator MutT protein
THTE_0759	ENOG4105BZU	Histidine kinase
THTE_0765	ENOG4105C9Q	fumarate hydratase class II
THTE_0767	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
THTE_0768	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THTE_0769	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
THTE_0770	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THTE_0771	ENOG4105GKE	subunit e
THTE_0776	ENOG41081XG	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THTE_0777	ENOG4105DF2	NADH dehydrogenase subunit j
THTE_0778	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THTE_0779	ENOG4105D65	subunit l
THTE_0781	ENOG4105C8S	subunit m
THTE_0782	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THTE_0783	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
THTE_0788	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
THTE_0793	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
THTE_0803	ENOG4108V5V	Serine Threonine protein kinase
THTE_0805	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
THTE_0806	ENOG4105CDA	abc transporter atp-binding protein
THTE_0807	ENOG4105E5Q	amino acid AbC transporter
THTE_0816	ENOG4105CJ1	ABC, transporter
THTE_0818	ENOG4105CBG	Sulfatase
THTE_0822	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
THTE_0825	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
THTE_0829	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
THTE_0830	ENOG4105DZP	Membrane-associated zinc metalloprotease
THTE_0831	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
THTE_0837	ENOG4105D3Q	Sugar transferase
THTE_0839	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
THTE_0843	ENOG4105K63	Thioredoxin
THTE_0844	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
THTE_0849	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
THTE_0850	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
THTE_0853	ENOG4105BZU	Histidine kinase
THTE_0854	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THTE_0855	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
THTE_0860	ENOG4105D9P	serine threonine protein kinase
THTE_0864	ENOG4108Q52	Methyltransferase cognate corrinoid protein
THTE_0865	ENOG4105CHR	reductase
THTE_0866	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
THTE_0868	ENOG4108JQ7	(ABC) transporter
THTE_0869	ENOG4105C3U	ABC transporter
THTE_0870	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
THTE_0873	ENOG4105D07	Signal peptide peptidase, SppA
THTE_0874	ENOG4108IJ6	ABC transporter
THTE_0875	ENOG4105ECW	sulfate abc transporter
THTE_0876	ENOG4107Z6A	sulfate abc transporter permease
THTE_0877	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
THTE_0878	ENOG4108JUA	Transcriptional regulator
THTE_0881	ENOG41061MV	Arylsulfatase
THTE_0883	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
THTE_0885	ENOG4108IUW	ABC transporter
THTE_0886	ENOG4105EGS	Mechanosensitive ion channel
THTE_0900	ENOG41061MV	Arylsulfatase
THTE_0901	ENOG4107QI1	Mate efflux family protein
THTE_0903	ENOG4105CAS	nag kinase
THTE_0905	ENOG4105C8Y	Acetylornithine aminotransferase
THTE_0906	ENOG4105DBV	ornithine carbamoyltransferase
THTE_0907	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
THTE_0909	ENOG4105D22	carbon starvation protein
THTE_0918	ENOG4105C3R	Methionine synthase
THTE_0926	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
THTE_0927	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
THTE_0928	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
THTE_0930	ENOG4105DJV	ribulose-phosphate 3-epimerase
THTE_0937	ENOG4105WMR	Protein CrcB homolog
THTE_0938	ENOG4105KJJ	Uncharacterized ACR, COG1993
THTE_0939	ENOG4108USZ	hydrogenase
THTE_0940	ENOG4107TPY	serine threonine protein kinase
THTE_0944	ENOG4108A51	
THTE_0945	ENOG4108V4M	Cobalt abc transporter
THTE_0946	ENOG4108JJB	ABC transporter
THTE_0957	ENOG4108V3W	Chemotaxis protein, CheW
THTE_0958	ENOG4105C8Q	Methyl-accepting chemotaxis
THTE_0959	ENOG4108ZXC	Two component transcriptional regulator, luxr family
THTE_0961	ENOG4105BZU	Histidine kinase
THTE_1026	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
THTE_1027	ENOG4107RSS	Hydrogenase accessory protein HypB
THTE_1028	ENOG4108UXE	Protein tyrosine phosphatase
THTE_1029	ENOG4106H78	methyltransferase
THTE_1032	ENOG4105BZU	Histidine kinase
THTE_1039	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
THTE_1040	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
THTE_1048	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THTE_1051	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
THTE_1053	ENOG4105DC7	peptidase M24
THTE_1055	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
THTE_1056	ENOG4105CTQ	phosphohexokinase
THTE_1063	ENOG4105MRR	Transcriptional regulator (By similarity)
THTE_1064	ENOG4105CDY	transcriptional regulatory protein
THTE_1067	ENOG41082YX	Transcriptional regulator, arsr family
THTE_1075	ENOG4105CIG	ABC transporter
THTE_1076	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
THTE_1077	ENOG4105QNJ	serralysin (EC 3.4.24.40)
THTE_1078	ENOG4105D8V	Glucose sorbosone dehydrogenase
THTE_1087	ENOG41083AB	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
THTE_1090	ENOG4105BZU	Histidine kinase
THTE_1091	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THTE_1092	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
THTE_1093	ENOG4108ZC9	flagellar basal-body rod protein flgc
THTE_1094	ENOG4108844	flagellar hook-basal body complex protein fliE
THTE_1096	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
THTE_1102	ENOG4105W00	Flagellar hook capping protein
THTE_1103	ENOG4105BZE	flagellar hook protein, FlgE
THTE_1104	ENOG41068WV	flagellar FlbD family protein
THTE_1105	ENOG4105E14	MotA TolQ exbB proton channel
THTE_1106	ENOG4105ER2	Ompa motb domain protein
THTE_1108	ENOG4105DD5	Flagellar motor switch protein
THTE_1110	ENOG4105CN7	Flagellar biosynthetic protein FliP
THTE_1111	ENOG4105VS8	Flagellar biosynthetic protein fliq
THTE_1113	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
THTE_1114	ENOG4105D00	flagellar biosynthetic protein flhB
THTE_1117	ENOG4105D7B	Flagellar biosynthesis protein flha
THTE_1119	ENOG4105FZW	flagellar biosynthesis regulator FlhF
THTE_1123	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THTE_1133	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
THTE_1136	ENOG4105SFS	phosphoesterase RecJ domain protein
THTE_1139	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
THTE_1142	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
THTE_1144	ENOG4107ZPS	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
THTE_1145	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
THTE_1146	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
THTE_1147	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
THTE_1148	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
THTE_1149	ENOG41082XA	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
THTE_1152	ENOG4105D7W	serine acetyltransferase
THTE_1153	ENOG4105CJ1	ABC, transporter
THTE_1156	ENOG4105CXT	aspartate transcarbamylase
THTE_1157	ENOG4105CD3	dihydroorotase
THTE_1159	ENOG4107QNG	Phosphoribosylglycinamide synthetase
THTE_1168	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
THTE_1172	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THTE_1181	ENOG4105E3H	phosphoglycerate mutase
THTE_1184	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
THTE_1196	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
THTE_1202	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
THTE_1203	ENOG4105D48	metallophosphoesterase
THTE_1211	ENOG4108WZM	domain protein
THTE_1212	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
THTE_1213	ENOG4105VIE	preprotein translocase, subunit YajC
THTE_1227	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
THTE_1228	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
THTE_1240	ENOG41061MV	Arylsulfatase
THTE_1242	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
THTE_1243	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
THTE_1262	ENOG4105D9P	serine threonine protein kinase
THTE_1264	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
THTE_1267	ENOG41082DI	50s ribosomal protein l31
THTE_1268	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
THTE_1269	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
THTE_1276	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
THTE_1282	ENOG4109015	Biopolymer transport protein exbD tolR
THTE_1283	ENOG4109015	Biopolymer transport protein exbD tolR
THTE_1288	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
THTE_1289	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
THTE_1290	ENOG4105CPK	Glycosyl transferase (Group 1
THTE_1292	ENOG4105CAQ	asparagine synthetase
THTE_1294	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
THTE_1296	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
THTE_1299	ENOG4105CH7	arginosuccinase
THTE_1304	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THTE_1306	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
THTE_1308	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
THTE_1314	ENOG4105E98	transcriptional regulator DeoR family
THTE_1315	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
THTE_1316	ENOG4105KNY	Microcompartments protein
THTE_1317	ENOG4105KNY	Microcompartments protein
THTE_1319	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
THTE_1320	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
THTE_1321	ENOG4108EKI	Dehydrogenase
THTE_1330	ENOG4105C0P	Mg chelatase subunit ChlI
THTE_1332	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
THTE_1333	ENOG4108YZG	isomerase
THTE_1337	ENOG4107QHF	type ii secretion system protein e
THTE_1340	ENOG4108JU3	Alkyl hydroperoxide reductase
THTE_1349	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
THTE_1351	ENOG4105C0H	protease
THTE_1354	ENOG4107RJ5	oxidoreductase
THTE_1356	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THTE_1360	ENOG4105C8T	Leucyl-tRNA synthetase
THTE_1365	ENOG4107VG4	Xylose isomerase domain protein TIM barrel
THTE_1366	ENOG4105C8Q	Methyl-accepting chemotaxis
THTE_1368	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
THTE_1370	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
THTE_1371	ENOG4105GVR	general secretion pathway protein D
THTE_1376	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
THTE_1384	ENOG4105DUX	Transporter
THTE_1386	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
THTE_1387	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
THTE_1388	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
THTE_1389	ENOG410855W	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
THTE_1390	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THTE_1391	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
THTE_1392	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
THTE_1393	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
THTE_1394	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
THTE_1395	ENOG4107FF9	50s ribosomal protein l29
THTE_1396	ENOG41084D8	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
THTE_1397	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
THTE_1398	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
THTE_1399	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
THTE_1401	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
THTE_1402	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
THTE_1403	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
THTE_1404	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
THTE_1405	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
THTE_1406	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
THTE_1407	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
THTE_1409	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THTE_1410	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
THTE_1411	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
THTE_1412	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THTE_1413	ENOG4107ZZ0	50S ribosomal protein L17
THTE_1424	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
THTE_1431	ENOG4105CBG	Sulfatase
THTE_1439	ENOG4107QQG	Dehydrogenase
THTE_1441	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
THTE_1448	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
THTE_1450	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
THTE_1451	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
THTE_1464	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
THTE_1465	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THTE_1467	ENOG4105DVT	helicase
THTE_1482	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
THTE_1486	ENOG4105C0H	protease
THTE_1488	ENOG4105CX8	fg-gap repeat protein
THTE_1490	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
THTE_1501	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THTE_1509	ENOG4108JIG	Anaerobic dehydrogenase
THTE_1512	ENOG4108UDB	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
THTE_1513	ENOG4105BZ8	glutamate synthase
THTE_1514	ENOG41062ES	Transcriptional regulator
THTE_1526	ENOG4105DF6	Fe-S oxidoreductase
THTE_1529	ENOG4105DF6	Fe-S oxidoreductase
THTE_1533	ENOG4105DAA	L-lactate
THTE_1543	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
THTE_1546	ENOG4105C1J	atp-dependent rna helicase
THTE_1555	ENOG4107ZVI	PhiRv2 prophage protein
THTE_1559	ENOG4107T0X	DNA ligase
THTE_1564	ENOG4105CBG	Sulfatase
THTE_1570	ENOG4105CJ2	(LipO)protein
THTE_1575	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
THTE_1577	ENOG4106678	morphogenetic protein associated with SpoVID
THTE_1578	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
THTE_1587	ENOG4105ERH	Fumarylacetoacetate hydrolase
THTE_1589	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
THTE_1593	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
THTE_1594	ENOG4107QSI	ABC, transporter
THTE_1597	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_1601	ENOG4105C0H	protease
THTE_1603	ENOG4105EPC	oxidoreductase
THTE_1604	ENOG4105EMN	RNA polymerase sigma factor
THTE_1606	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
THTE_1611	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
THTE_1613	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
THTE_1620	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
THTE_1625	ENOG4105CFG	Acts as a chaperone (By similarity)
THTE_1628	ENOG4105CN1	protease
THTE_1631	ENOG4105DET	Rhamnulokinase
THTE_1635	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
THTE_1646	ENOG4105D7Q	type ii secretion system
THTE_1648	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
THTE_1653	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
THTE_1654	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
THTE_1663	ENOG4105T16	Transcriptional regulator (AraC family)
THTE_1671	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
THTE_1673	ENOG41084AE	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
THTE_1678	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
THTE_1679	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
THTE_1680	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THTE_1681	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
THTE_1682	ENOG4107UFS	subunit j
THTE_1684	ENOG4105D65	subunit l
THTE_1685	ENOG4105C8S	subunit m
THTE_1686	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THTE_1688	ENOG4105F8V	Hydrolase, tatD family
THTE_1690	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
THTE_1697	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
THTE_1698	ENOG4105M7K	Involved in the transcription termination process (By similarity)
THTE_1699	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
THTE_1700	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
THTE_1701	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
THTE_1702	ENOG4105C2M	dna polymerase I
THTE_1706	ENOG4105DAP	Nicotinate phosphoribosyltransferase
THTE_1707	ENOG4105C4K	Nad synthetase
THTE_1708	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
THTE_1709	ENOG4108RWI	nicotinamidase
THTE_1711	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
THTE_1712	ENOG4105C2X	Arabinose 5-phosphate isomerase
THTE_1717	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
THTE_1719	ENOG4107PU6	Membrane
THTE_1724	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
THTE_1741	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
THTE_1759	ENOG4107ZVI	PhiRv2 prophage protein
THTE_1784	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
THTE_1785	ENOG4105EGD	dinuclear metal center protein, YbgI family
THTE_1788	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
THTE_1789	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
THTE_1795	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
THTE_1797	ENOG4105CKU	formyltetrahydrofolate synthetase
THTE_1798	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
THTE_1809	ENOG4108JUA	Transcriptional regulator
THTE_1810	ENOG4108UVJ	appr-1-p processing domain protein
THTE_1811	ENOG4105D7Q	type ii secretion system
THTE_1815	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
THTE_1818	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
THTE_1820	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
THTE_1825	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
THTE_1826	ENOG4105CHM	Aminotransferase
THTE_1831	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
THTE_1833	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
THTE_1836	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
THTE_1839	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
THTE_1840	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
THTE_1843	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
THTE_1846	ENOG410667J	hydrolase
THTE_1850	ENOG4105CNV	Aldolase
THTE_1854	ENOG4105E8R	UPF0173 metal-dependent hydrolase
THTE_1855	ENOG4107QYV	phosphohexose isomerase
THTE_1860	ENOG4105C2N	RNA methyltransferase TrmH family group 3
THTE_1870	ENOG4105BZU	Histidine kinase
THTE_1874	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
THTE_1875	ENOG4105C8U	phosphate abc transporter
THTE_1876	ENOG4105C8U	phosphate abc transporter
THTE_1879	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
THTE_1882	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
THTE_1883	ENOG4105CY0	Metallo-Beta-Lactamase
THTE_1890	ENOG4105F9U	Dehydrogenase
THTE_1892	ENOG4105DG6	mannose-6-phosphate isomerase
THTE_1894	ENOG4108JA2	transcriptioN-repair coupling factor
THTE_1895	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
THTE_1905	ENOG4105ES5	Histidine kinase
THTE_1910	ENOG4105BZU	Histidine kinase
THTE_1912	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THTE_1913	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THTE_1914	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THTE_1916	ENOG4105D9P	serine threonine protein kinase
THTE_1918	ENOG4105C7K	acetolactate synthase
THTE_1925	ENOG4105EPC	oxidoreductase
THTE_1934	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THTE_1936	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_1947	ENOG4105DA5	(ABC) transporter
THTE_1950	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
THTE_1953	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_1956	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
THTE_1957	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
THTE_1961	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THTE_1964	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
THTE_1965	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
THTE_1967	ENOG4105C5H	ABC transporter
THTE_1968	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
THTE_1969	ENOG4105C1G	acyl-Coa dehydrogenase
THTE_1970	ENOG4105C10	Electron transfer flavoprotein
THTE_1971	ENOG4105BZJ	Electron transfer flavoprotein
THTE_1980	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
THTE_1981	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
THTE_1983	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
THTE_1984	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
THTE_1986	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
THTE_1994	ENOG4105CBG	Sulfatase
THTE_1996	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_1998	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
THTE_2002	ENOG410827H	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
THTE_2011	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
THTE_2012	ENOG4105M8K	biopolymer transport protein
THTE_2017	ENOG4105EPC	oxidoreductase
THTE_2018	ENOG4105EUJ	GTP cyclohydrolase i
THTE_2019	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
THTE_2024	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
THTE_2025	ENOG4105C31	Tryptophanyl-tRNA synthetase
THTE_2027	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
THTE_2030	ENOG41066A3	ATP guanido phosphotransferase
THTE_2031	ENOG4105CBG	Sulfatase
THTE_2037	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
THTE_2039	ENOG41088YS	Glycosyl transferase (Group 1
THTE_2041	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
THTE_2044	ENOG4105CBG	Sulfatase
THTE_2052	ENOG4108Q52	Methyltransferase cognate corrinoid protein
THTE_2057	ENOG4105CBG	Sulfatase
THTE_2066	ENOG41061MV	Arylsulfatase
THTE_2069	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
THTE_2071	ENOG4105DB1	molybdopterin oxidoreductase
THTE_2073	ENOG4105DTQ	mandelate racemase muconate lactonizing
THTE_2082	ENOG4105C9X	ppx gppa phosphatase
THTE_2083	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
THTE_2084	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
THTE_2085	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
THTE_2086	ENOG4105WKW	Pfam:DUF1458
THTE_2087	ENOG4105C5X	domain protein
THTE_2103	ENOG4105DKG	l-rhamnose isomerase
THTE_2109	ENOG4105EX0	alpha-galactosidase
THTE_2111	ENOG4105C93	Xylose Isomerase
THTE_2112	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
THTE_2116	ENOG4105IDI	abc transporter atp-binding protein
THTE_2118	ENOG4107QPV	Serine Threonine protein kinase
THTE_2127	ENOG4108YZ4	nudix hydrolase
THTE_2130	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
THTE_2137	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
THTE_2140	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
THTE_2142	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
THTE_2143	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
THTE_2153	ENOG4108NWD	Cytochrome
THTE_2160	ENOG4105C0H	protease
THTE_2163	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
THTE_2169	ENOG4105D6J	arsenicaL-resistance protein
THTE_2175	ENOG4105E2R	ROK family
THTE_2182	ENOG4105CSR	polyphosphate kinase 2
THTE_2183	ENOG4105D9N	nucleoside
THTE_2185	ENOG4105CQB	FAD linked oxidase domain protein
THTE_2186	ENOG4105EU8	FAD linked oxidase domain protein
THTE_2189	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
THTE_2190	ENOG4105CTQ	phosphohexokinase
THTE_2191	ENOG4107Y7Q	pfkb domain protein
THTE_2192	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
THTE_2200	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
THTE_2201	ENOG4105W8H	transhydrogenase (subunit alpha
THTE_2202	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
THTE_2205	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
THTE_2208	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THTE_2211	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
THTE_2212	ENOG4105C26	Dehydrogenase
THTE_2216	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
THTE_2218	ENOG4105CRQ	synthase (Component I)
THTE_2219	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
THTE_2220	ENOG4105D1F	ATP-binding protein
THTE_2232	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
THTE_2237	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
THTE_2238	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THTE_2248	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
THTE_2249	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
THTE_2250	ENOG4108RVA	ribokinase
THTE_2255	ENOG4105C0B	DNA polymerase III (alpha subunit)
THTE_2261	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
THTE_2263	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_2269	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
THTE_2272	ENOG4105C9M	aspartyl-trna synthetase
THTE_2274	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
THTE_2275	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
THTE_2276	ENOG4105CBG	Sulfatase
THTE_2278	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
THTE_2279	ENOG4105FJR	Lmbe family
THTE_2280	ENOG4105C34	Pseudouridine synthase
THTE_2289	ENOG4105D9P	serine threonine protein kinase
THTE_2290	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
THTE_2291	ENOG4108KMV	Glycosyl transferase (Group 1
THTE_2293	ENOG4105C9B	Cysteine desulfurase
THTE_2294	ENOG4108UNV	SUF system FeS assembly protein, NifU family
THTE_2296	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
THTE_2309	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
THTE_2311	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THTE_2312	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THTE_2313	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_2315	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
THTE_2321	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
THTE_2323	ENOG4105ENH	Sulfatase
THTE_2324	ENOG4105CBG	Sulfatase
THTE_2341	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
THTE_2344	ENOG4108IAJ	Nad-dependent epimerase dehydratase
THTE_2345	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
THTE_2348	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THTE_2353	ENOG4105K64	Glycosyl transferase, family 2
THTE_2354	ENOG4107RRD	Dehydrogenase
THTE_2356	ENOG4105JNK	Glycosyl transferase (Group 1
THTE_2358	ENOG4106WTF	Glycosyl transferase, family 2
THTE_2362	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
THTE_2365	ENOG4105E2K	Glycosyl transferase (Group 1
THTE_2368	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
THTE_2371	ENOG4108SHN	Glycosyl transferase, family 2
THTE_2375	ENOG4105EY8	ABC transporter
THTE_2378	ENOG4105ESV	Glycosyl transferase, family 4
THTE_2380	ENOG4108QV3	biosynthesis protein
THTE_2385	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
THTE_2390	ENOG41061MV	Arylsulfatase
THTE_2395	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
THTE_2403	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
THTE_2404	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
THTE_2405	ENOG4105D06	uba thif-type nad fad binding protein
THTE_2409	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
THTE_2410	ENOG4105EYF	MMPL domain protein
THTE_2414	ENOG4107YTP	response regulator receiver protein
THTE_2425	ENOG4107VAM	peptidase, m28
THTE_2427	ENOG4105C2J	ABC transporter
THTE_2428	ENOG4105CNN	ABC, transporter
THTE_2432	ENOG4105C25	Primosomal protein n'
THTE_2433	ENOG4105BZU	Histidine kinase
THTE_2435	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
THTE_2437	ENOG4105DVY	radical SAM domain protein
THTE_2438	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
THTE_2439	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
THTE_2440	ENOG4107Y6J	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
THTE_2442	ENOG4108N5B	2-phosphosulfolactate phosphatase
THTE_2447	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
THTE_2448	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
THTE_2449	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
THTE_2452	ENOG4105EQI	Metal Dependent Phosphohydrolase
THTE_2458	ENOG4108UJD	30S ribosomal protein S9
THTE_2459	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
THTE_2461	ENOG4105D4A	Cell wall formation (By similarity)
THTE_2465	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
THTE_2466	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THTE_2471	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
THTE_2473	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
THTE_2475	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
THTE_2477	ENOG4105DDQ	anthranilate synthase
THTE_2478	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
THTE_2479	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
THTE_2482	ENOG4108FN7	Aldo keto reductase
THTE_2485	ENOG4108UQY	Iron-storage protein
THTE_2494	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
THTE_2496	ENOG4105C0H	protease
THTE_2498	ENOG4105DU1	integral membrane protein, terc
THTE_2499	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
THTE_2507	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
THTE_2508	ENOG4105CFG	Acts as a chaperone (By similarity)
THTE_2510	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
THTE_2511	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
THTE_2514	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
THTE_2522	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
THTE_2526	ENOG41080XP	Cbs domain
THTE_2529	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
THTE_2537	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
THTE_2539	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
THTE_2540	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
THTE_2541	ENOG4105CDH	Citrulline--aspartate ligase
THTE_2543	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
THTE_2545	ENOG4105CSM	endonuclease III
THTE_2550	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
THTE_2551	ENOG4105DDQ	anthranilate synthase
THTE_2553	ENOG4105DD5	Flagellar motor switch protein
THTE_2559	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THTE_2560	ENOG4107HQ7	repeat protein
THTE_2573	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_2575	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
THTE_2577	ENOG41061MV	Arylsulfatase
THTE_2579	ENOG4107Y30	Maf-like protein
THTE_2580	ENOG4105K70	DNA-binding protein
THTE_2582	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
THTE_2591	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
THTE_2592	ENOG4105CHR	reductase
THTE_2593	ENOG41083PU	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
THTE_2594	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
THTE_2598	ENOG4105SCY	DNAK suppressor
THTE_2599	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
THTE_2611	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THTE_2615	ENOG4105D49	3-dehydroquinate synthase
THTE_2616	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
THTE_2617	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
THTE_2618	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
THTE_2620	ENOG4105DI5	UPF0365 protein
THTE_2621	ENOG4105CK5	oxidoreductase
THTE_2626	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
THTE_2628	ENOG4108YZA	Nitrogen regulatory protein pii
THTE_2629	ENOG4105CTQ	phosphohexokinase
THTE_2631	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
THTE_2632	ENOG4105CHR	reductase
THTE_2633	ENOG4105D7Q	type ii secretion system
THTE_2634	ENOG4107QHF	type ii secretion system protein e
THTE_2636	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THTE_2637	ENOG4105BZU	Histidine kinase
THTE_2639	ENOG4105E4G	Type IV pilus
THTE_2650	ENOG4105CJW	magnesium transporter
THTE_2651	ENOG4105C9B	Cysteine desulfurase
THTE_2652	ENOG4105C3J	Cysteine desulfurase
THTE_2653	ENOG4105DPN	Oligoendopeptidase f
THTE_2666	ENOG4105FE9	pseudouridine synthase
THTE_2667	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
THTE_2673	ENOG4107TYG	Oxidoreductase domain-containing protein
THTE_2676	ENOG4107QN2	dihydrolipoyl dehydrogenase
THTE_2679	ENOG41061MV	Arylsulfatase
THTE_2680	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
THTE_2681	ENOG4105C6E	dna polymerase iii
THTE_2688	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
THTE_2689	ENOG4105CIH	Imidazole acetol-phosphate transaminase
THTE_2694	ENOG4105DR9	pseudouridine synthase
THTE_2713	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
THTE_2733	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
THTE_2735	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
THTE_2739	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
THTE_2742	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
THTE_2744	ENOG4105NTD	Inherit from COG: Hydrolase
THTE_2764	ENOG4107R7Y	intracellular protease Pfpi family
THTE_2768	ENOG4105CVJ	phosphoglycerate mutase
THTE_2769	ENOG41061MV	Arylsulfatase
THTE_2773	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
THTE_2774	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
THTE_2780	ENOG4107QJE	Chromosome Partitioning Protein
THTE_2781	ENOG4105FA0	parb-like partition protein
THTE_2784	ENOG4108VYJ	response regulator receiver protein
THTE_2786	ENOG4107TYA	transient receptor potential locus
THTE_2790	ENOG4105C7N	Xanthine uracil vitamin C permease
THTE_2792	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
THTE_2795	ENOG4105EPC	oxidoreductase
THTE_2803	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THTE_2808	ENOG4107XCH	Cyclase family
THTE_2812	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
THTE_2817	ENOG4105C8Q	Methyl-accepting chemotaxis
THTE_2823	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
THTE_2824	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
THTE_2830	ENOG41067D4	cell wall surface anchor family protein
THTE_2837	ENOG4105WH1	Two component transcriptional regulator luxr family
THTE_2844	ENOG4108SET	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
THTE_2845	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
THTE_2846	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THTE_2848	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
THTE_2855	ENOG4105E68	Sulfatase
THTE_2857	ENOG4105BZU	Histidine kinase
THTE_2859	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
THTE_2861	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
THTE_2863	ENOG4105CMR	udp-glucose 4-epimerase
THTE_2866	ENOG4105CE1	Ferrous iron transport protein b
THTE_2871	ENOG4105ENH	Sulfatase
THTE_2875	ENOG4108Z6B	deaminase
THTE_2881	ENOG4107QHI	-hydrogenase
THTE_2882	ENOG4107QIZ	NADH dehydrogenase
THTE_2884	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
THTE_2889	ENOG4105VJV	50s ribosomal protein L35
THTE_2890	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
THTE_2896	ENOG4107SFQ	iron-sulfur binding
THTE_2903	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
THTE_2904	ENOG4105BZ9	Cytochrome C oxidase, subunit I
THTE_2907	ENOG4105CCU	oxidase (Subunit III)
THTE_2912	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
THTE_2913	ENOG4105E5G	Alpha beta hydrolase fold
THTE_2917	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
THTE_2919	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
THTE_2929	ENOG4105Y3U	Transglycosylase-associated protein
THTE_2932	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
THTE_2944	ENOG4105D9P	serine threonine protein kinase
THTE_2949	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
THTE_2952	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
THTE_2953	ENOG4105DVC	DnaJ domain protein
THTE_2963	ENOG4105D9P	serine threonine protein kinase
THTE_2965	ENOG4105CBG	Sulfatase
THTE_2968	ENOG4105KHN	chorismate mutase
THTE_2971	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
THTE_2973	ENOG4105C0H	protease
THTE_2980	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THTE_2989	ENOG4105C0H	protease
THTE_2992	ENOG4105C75	arginyL-tRNA synthetase
THTE_2995	ENOG4105CFG	Acts as a chaperone (By similarity)
THTE_2996	ENOG4105CD5	CoA-binding domain protein
THTE_3001	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
THTE_3002	ENOG4105D9P	serine threonine protein kinase
THTE_3008	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
THTE_3011	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
THTE_3014	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
THTE_3015	ENOG4105CTP	PilT protein domain protein
THTE_3022	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
THTE_3023	ENOG4105C1A	potassium transporter peripheral membrane
THTE_3026	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
THTE_3040	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
THTE_3046	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THTE_3048	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
THTE_3050	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
THTE_3051	ENOG4105E2K	Glycosyl transferase (Group 1
THTE_3055	ENOG4105E6M	Sulphatase-modifying factor protein
THTE_3066	ENOG4105UQX	Mate efflux family protein
THTE_3067	ENOG41061MV	Arylsulfatase
THTE_3074	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
THTE_3086	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
THTE_3087	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
THTE_3088	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
THTE_3089	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THTE_3090	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THTE_3091	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
THTE_3093	ENOG4107QHI	-hydrogenase
THTE_3094	ENOG4107QIZ	NADH dehydrogenase
THTE_3097	ENOG4105HEE	Binding Domain protein
THTE_3106	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
THTE_3107	ENOG4105BZU	Histidine kinase
THTE_3111	ENOG4105C0H	protease
THTE_3112	ENOG4105DK0	Indole-3-glycerol phosphate synthase
THTE_3118	ENOG4105C22	threonyL-tRNA synthetase
THTE_3120	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
THTE_3127	ENOG4107QM5	aconitate hydratase
THTE_3128	ENOG4108YBP	pseudouridine synthase
THTE_3130	ENOG4105CFG	Acts as a chaperone (By similarity)
THTE_3134	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
THTE_3135	ENOG4107VAM	peptidase, m28
THTE_3136	ENOG41085BB	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
THTE_3140	ENOG4105VF7	tolerance protein
THTE_3142	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
THTE_3143	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
THTE_3144	ENOG4105U6W	MutT NUDIX family protein
THTE_3145	ENOG4105C3J	Cysteine desulfurase
THTE_3146	ENOG4105D9P	serine threonine protein kinase
THTE_3147	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THTE_3153	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
THTE_3156	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
THTE_3157	ENOG4108FN7	Aldo keto reductase
THTE_3167	ENOG4108VAU	general secretion pathway protein G
THTE_3168	ENOG4105D7Q	type ii secretion system
THTE_3169	ENOG4107QHF	type ii secretion system protein e
THTE_3172	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
THTE_3174	ENOG4105BZ1	(ABC) transporter
THTE_3177	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
THTE_3179	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
THTE_3182	ENOG4105BZU	Histidine kinase
THTE_3185	ENOG4105E0R	Deoxyhypusine synthase
THTE_3189	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
THTE_3190	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
THTE_3191	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
THTE_3194	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
THTE_3198	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
THTE_3205	ENOG4107JTW	chlorite dismutase
THTE_3206	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
THTE_3207	ENOG4105DKQ	ROK family
THTE_3218	ENOG4105CBG	Sulfatase
THTE_3219	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
THTE_3238	ENOG4105ESV	Glycosyl transferase, family 4
THTE_3243	ENOG4105CRK	lysyL-tRNA synthetase
THTE_3244	ENOG4107VCI	FtsX-like permease family
THTE_3245	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
THTE_3247	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
THTE_3255	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
THTE_3264	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THTE_3266	ENOG4105E2K	Glycosyl transferase (Group 1
THTE_3268	ENOG4105BZU	Histidine kinase
THTE_3271	ENOG4105D05	Receptor
THTE_3273	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
THTE_3274	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
THTE_3275	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
THTE_3277	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
THTE_3284	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
THTE_3285	ENOG4105D9P	serine threonine protein kinase
THTE_3287	ENOG4108IYU	L-aspartate oxidase
THTE_3294	ENOG4105EAH	synthase
THTE_3295	ENOG4107X8Y	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
THTE_3297	ENOG4105D9P	serine threonine protein kinase
THTE_3305	ENOG4108EUP	Glycosyl hydrolase family 62 
THTE_3308	ENOG4105C0H	protease
THTE_3311	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
THTE_3315	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
THTE_3318	ENOG4105C8Q	Methyl-accepting chemotaxis
THTE_3329	ENOG4105EMN	RNA polymerase sigma factor
THTE_3331	ENOG4105CNU	cell division protein FtsK
THTE_3335	ENOG4107QJE	Chromosome Partitioning Protein
THTE_3339	ENOG41083CE	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
THTE_3340	ENOG4105CMQ	Chloride channel
THTE_3348	ENOG4105C5I	Dehydrogenase
THTE_3358	ENOG4105DKP	glycosyl transferase, family 9
THTE_3363	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
THTE_3366	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
THTE_3368	ENOG4105E0A	ABC, transporter
THTE_3370	ENOG4105CPC	Aldo Keto reductase
THTE_3374	ENOG4105BZA	Phosphoglycerate kinase
THTE_3375	ENOG4107S85	alpha-2-macroglobulin domain protein
THTE_3381	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
THTE_3385	ENOG4105EPC	oxidoreductase
THTE_3389	ENOG4107TJ6	metallophosphoesterase
THTE_3391	ENOG4105M08	Membrane
THTE_3394	ENOG4105DR4	Methyltransferase
THTE_3401	ENOG4105DCI	Phosphohydrolase
THTE_3405	ENOG4105E02	MotA TolQ exbB proton channel
THTE_3408	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
THTE_3412	ENOG4108WBT	adenosyltransferase
THTE_3414	ENOG4108YZA	Nitrogen regulatory protein pii
THTE_3416	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
THTE_3421	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
THTE_3422	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
THTE_3423	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
THTE_3430	ENOG4105ENX	hydrolase
THTE_3431	ENOG4105CA0	peroxidase
THTE_3433	ENOG4105CNT	hydrolase family 2
THTE_3437	ENOG4105CEV	competence damage-inducible protein
THTE_3461	ENOG4105CNA	YD repeat protein
THTE_3467	ENOG41090HT	Inherit from COG: transposase
THTE_3475	ENOG4107TFS	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
THTE_3478	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_3479	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_3481	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
THTE_3482	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
THTE_3483	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
THTE_3493	ENOG41061MV	Arylsulfatase
THTE_3495	ENOG4108YZA	Nitrogen regulatory protein pii
THTE_3498	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
THTE_3505	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
THTE_3506	ENOG41072GX	Peptidase M22 Glycoprotease
THTE_3509	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
THTE_3511	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
THTE_3512	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
THTE_3513	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
THTE_3514	ENOG4108VZM	50s ribosomal protein L10
THTE_3516	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
THTE_3517	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THTE_3518	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THTE_3519	ENOG4105CAT	Cytidine monophosphate kinase
THTE_3524	ENOG4105NTD	Inherit from COG: Hydrolase
THTE_3525	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
THTE_3526	ENOG4108FN7	Aldo keto reductase
THTE_3527	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
THTE_3528	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
THTE_3529	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
THTE_3530	ENOG4105CHR	reductase
THTE_3531	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
THTE_3536	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
THTE_3537	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
THTE_3540	ENOG4105D7N	magnesium and cobalt transport protein CorA
THTE_3547	ENOG4107RGD	Major Facilitator superfamily
THTE_3547	ENOG4107RGD	Major Facilitator superfamily
THTE_3554	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
THTE_3560	ENOG4105N5T	Radical SAM Protein
THTE_3562	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
THTE_3563	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
THTE_3564	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
THTE_3571	ENOG4105C4R	Atp-dependent dna helicase
THTE_3572	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
THTE_3574	ENOG4105CBG	Sulfatase
THTE_3576	ENOG4108DMA	Nad-dependent epimerase dehydratase
THTE_3577	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THTE_3585	ENOG4105D2H	Uronic isomerase
THTE_3600	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
THTE_3601	ENOG4105CX8	fg-gap repeat protein
THTE_3602	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
THTE_3603	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
THTE_3604	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
THTE_3605	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THTE_3606	ENOG4105K46	50S ribosomal protein l27
THTE_3608	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
THTE_3614	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
THTE_3622	ENOG4105EMU	Dehydrogenase
THTE_3626	ENOG4107S9R	deoxycytidine triphosphate deaminase
THTE_3633	ENOG4105CDU	Replicative dna helicase
THTE_3634	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
THTE_3641	ENOG4105XA0	heptosyltransferase ii
THTE_3643	ENOG4105D1S	lipid A biosynthesis
THTE_3645	ENOG4105DSQ	Nitric oxide reductase
THTE_3647	ENOG4105KPV	Transcriptional regulator
THTE_3650	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
THTE_3655	ENOG4108IUZ	ABC transporter
THTE_3657	ENOG4105C3F	Signal peptidase i
THTE_3662	ENOG4107QJE	Chromosome Partitioning Protein
THTE_3667	ENOG4105BZS	acriflavin resistance protein
THTE_3674	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
THTE_3675	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
THTE_3676	ENOG4105BZU	Histidine kinase
THTE_3680	ENOG4107R6D	beta-lactam binding protein AmpH
THTE_3681	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
THTE_3692	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
THTE_3693	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
THTE_3695	ENOG41085CY	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
THTE_3696	ENOG4108JU5	Magnesium and cobalt efflux protein
THTE_3700	ENOG4108RAV	Conserved protein
THTE_3706	ENOG4105C0A	alcohol dehydrogenase
THTE_3710	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
THTE_3712	ENOG4105C0H	protease
THTE_3713	ENOG4108HPI	phosphatidate Cytidylyltransferase
THTE_3714	ENOG4108R1E	Serine threonine protein phosphatase 1
THTE_3719	ENOG4105C8V	SAICAR synthetase
THTE_3725	ENOG4105CFP	Peptidase U32
THTE_3726	ENOG4105ENH	Sulfatase
THTE_3732	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
THTE_3733	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
THTE_3735	ENOG4105D1Z	hydroxypyruvate reductase
THTE_3738	ENOG4107QI6	Cysteine desulfurase
THTE_3749	ENOG4107R88	Chemotaxis protein (CheV)
THTE_3752	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
THTE_3757	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
THTE_3760	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
THTE_3763	ENOG4105DI5	UPF0365 protein
THTE_3769	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
THTE_3774	ENOG4108IJF	Heavy metal efflux pump, CzcA
THTE_3780	ENOG4105C0H	protease
THTE_3782	ENOG4108Z86	Glutamine amidotransferase
THTE_3783	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
THTE_3794	ENOG4105CRE	cytochrome C
THTE_3797	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
THTE_3800	ENOG4107QNM	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
THTE_3803	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
THTE_3808	ENOG4105DGU	Histone deacetylase
THTE_3809	ENOG4105C2J	ABC transporter
THTE_3812	ENOG4105C9B	Cysteine desulfurase
THTE_3814	ENOG4105ECY	inositol monophosphatase
THTE_3820	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THTE_3826	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THTE_3827	ENOG4105M7V	2'-5' rna ligase
THTE_3828	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
THTE_3830	ENOG4105CAG	UPF0210 protein
THTE_3838	ENOG4105CBG	Sulfatase
THTE_3840	ENOG4105EPC	oxidoreductase
THTE_3842	ENOG4107QIZ	NADH dehydrogenase
THTE_3843	ENOG4107QHI	-hydrogenase
THTE_3844	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
THTE_3847	ENOG41084AE	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
THTE_3854	ENOG4108Z4U	Ferredoxin
THTE_3857	ENOG4105CCT	upf0313 protein
THTE_3859	ENOG4105CFG	Acts as a chaperone (By similarity)
THTE_3861	ENOG4107QR8	Thioredoxin
THTE_3862	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
THTE_3868	ENOG4105E33	succinate dehydrogenase
THTE_3870	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
THTE_3883	ENOG4105EY8	ABC transporter
THTE_3889	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
THTE_3890	ENOG4105K64	Glycosyl transferase, family 2
THTE_3891	ENOG4105EVB	acetyltransferase
THTE_3894	ENOG4107RA4	Glycosyl transferase (Group 1
THTE_3896	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THTE_3897	ENOG4105DCG	PHP domain protein
THTE_3898	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
THTE_3900	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
THTE_3901	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THTE_3911	ENOG4105CKK	Glycosyl transferase, family 2
THTE_3914	ENOG4105WH1	Two component transcriptional regulator luxr family
THTE_3915	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THTE_3926	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
THTE_3927	ENOG4107QRG	dna polymerase iii
THTE_3936	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THTE_3937	ENOG4105C28	cystathionine
THTE_3938	ENOG4105C28	cystathionine
THTE_3943	ENOG4105EAA	nucleoside
THTE_3946	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THTE_3947	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
THTE_3948	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
THTE_3949	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
THTE_3951	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
THTE_3958	ENOG4105DFA	alanine racemase domain protein
THTE_3959	ENOG4105VZ9	UPF0235 protein
THTE_3960	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
THTE_3964	ENOG4105C6T	cysteine synthase
THTE_3969	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
THTE_3972	ENOG4105CIY	formyltetrahydrofolate deformylase
THTE_3976	ENOG4105CPQ	Dehydrogenase
THTE_3979	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
THTE_3981	ENOG4105FE1	phytoene synthase
THTE_3987	ENOG4105CRQ	synthase (Component I)
THTE_3992	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
THTE_3994	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THTE_3995	ENOG4105CN9	Peptidase m42 family protein
THTE_4000	ENOG4107YTP	response regulator receiver protein
THTE_4005	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
THTE_4010	ENOG4105FDK	ABC transporter
THTE_4013	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
THTE_4015	ENOG4108UUM	single-stranded DNA-binding protein
THTE_4016	ENOG410843B	Binds together with S18 to 16S ribosomal RNA (By similarity)
THTE_4017	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
THTE_4018	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
THTE_4020	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
THTE_4032	ENOG4105CTJ	Metal Dependent Phosphohydrolase
THTE_4033	ENOG4105C9A	Phoh family
THTE_4037	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
THTE_4041	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THTE_4044	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
THTE_4047	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
THTE_4050	ENOG4105C1V	Peptidase, M16
THTE_4053	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
THTE_4054	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
THTE_4058	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
THTE_4061	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THTE_4083	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
THTE_4092	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
THTE_4098	ENOG4105DDI	hemolysin-type calcium-binding region
THTE_4101	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_4104	ENOG4105C03	ribonuclease
THTE_4119	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THTE_4129	ENOG4105CKK	Glycosyl transferase, family 2
THTE_4136	ENOG4105EJG	cellulose synthase
THTE_4138	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
THTE_4139	ENOG4105CEC	DNA methylase N-4 N-6
THTE_4153	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
THTE_4157	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
THTE_4177	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
THTE_4179	ENOG4105BZU	Histidine kinase
THTE_4180	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
THTE_4181	ENOG4105CX6	glutaminyL-tRNA synthetase
THTE_4184	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
THTE_4188	ENOG4105E2X	shikimate dehydrogenase
THTE_4189	ENOG4107ZTF	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
THTE_4190	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
THTE_4192	ENOG4105DCF	alanine dehydrogenase
THTE_4194	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
THTE_4211	ENOG4105CHM	Aminotransferase
THTE_4217	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
THTE_4222	ENOG4105C7Z	Conserved Protein
THTE_4229	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
THTE_4236	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
THTE_4239	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
THTE_4253	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
THTE_4258	ENOG4105CHM	Aminotransferase
THTE_4264	ENOG4105MA4	psp1 domain protein
THTE_4269	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
THTE_4278	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
THTE_4279	ENOG4105CA0	peroxidase
THTE_4280	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
THTE_4282	ENOG4105CBS	Chea signal transduction histidine kinase
THTE_4294	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
THTE_4296	ENOG4105VG1	fes assembly suf system protein
THTE_4298	ENOG4105JRK	feS assembly protein SufD
THTE_4299	ENOG4105DIW	FeS assembly protein SUFB
THTE_4300	ENOG4105C3K	feS assembly ATPase SufC
THTE_4301	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THTE_4304	ENOG4105C8J	)-transporter
THTE_4308	ENOG41086B8	CoB-CoM heterodisulfide reductase
THTE_4310	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
THTE_4317	ENOG4105DTT	CRISPR-associated helicase, cas3
THTE_4319	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
THTE_4320	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
THTE_4326	ENOG410842T	Pterin carbinolamine dehydratase
THTE_4332	ENOG410875G	30S ribosomal protein S21
THTE_4344	ENOG4105K63	Thioredoxin
THTE_4352	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
THTE_4353	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
THTE_4355	ENOG4105CGA	flagellar basal-body rod protein FlgG
THTE_4356	ENOG4105CGA	flagellar basal-body rod protein FlgG
THTE_4360	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
THTE_4363	ENOG4105DM4	PTS System
THTE_4364	ENOG41080Z8	PHOSPHOCARRIER protein
THTE_4365	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
THTE_4366	ENOG4107SET	aldo keto reductase
THTE_4369	ENOG4109015	Biopolymer transport protein exbD tolR
THTE_4372	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
THTE_4377	ENOG4108YZG	isomerase
THTE_4380	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
THTE_4382	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
THTE_4385	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
THTE_4389	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
THTE_4395	ENOG4105DWF	phosphomethylpyrimidine kinase
THTE_4396	ENOG41061AI	Protein of unknown function (DUF2905)
THTE_4397	ENOG4107TAE	Glycosyl transferase (Group 1
THTE_4402	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
THTE_4405	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
THTE_4410	ENOG41087N2	50S ribosomal protein l28
THTE_4411	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
THTE_4446	ENOG4105DQX	Zinc finger domain
THTE_4447	ENOG4107YK1	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
THTE_4452	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
THTE_4453	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
THTE_4456	ENOG4105D52	delta-aminolevulinic acid dehydratase
THTE_4460	ENOG4108V1U	phospholipid-binding protein
THTE_4462	ENOG41080SX	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
THTE_4463	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
THTE_4464	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
THTE_4469	ENOG4105K4W	Could be involved in septation (By similarity)
THTE_4470	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
THTE_4478	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THTE_4485	ENOG4105C3G	gtp-binding protein
THTE_4487	ENOG4105EMN	RNA polymerase sigma factor
THTE_4491	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
THTE_4494	ENOG4108M1T	Cytochrome c-type biogenesis protein