locus-tag	class	description
HPC62_00130	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_00160	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HPC62_00165	ENOG4108JJA	ABC, transporter
HPC62_00175	ENOG4105BZ1	(ABC) transporter
HPC62_00250	ENOG4108R0D	protein with myosin-like
HPC62_00255	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
HPC62_00260	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HPC62_00310	ENOG4105D1H	recombination factor protein RarA
HPC62_00340	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HPC62_00365	ENOG4105VMP	Transcriptional regulator
HPC62_00390	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HPC62_00430	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HPC62_00450	ENOG41063JG	Transcriptional regulator
HPC62_00460	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPC62_00465	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HPC62_00475	ENOG4105C9B	Cysteine desulfurase
HPC62_00490	ENOG4105VFU	Rna-binding protein
HPC62_00495	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HPC62_00505	ENOG4105K6T	rare lipoprotein A
HPC62_00515	ENOG4105DZP	Membrane-associated zinc metalloprotease
HPC62_00520	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HPC62_00525	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HPC62_00540	ENOG4105C89	phosphohexose isomerase
HPC62_00560	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
HPC62_00590	ENOG4107QI6	Cysteine desulfurase
HPC62_00595	ENOG4108HMN	Caspase domain
HPC62_00600	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HPC62_00620	ENOG4106E83	A core subunit of photosystem II (PSII) (By similarity)
HPC62_00625	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HPC62_00630	ENOG4107YU2	histidine triad (hIT) protein
HPC62_00670	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HPC62_00690	ENOG4105ETX	regulatoR
HPC62_00710	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HPC62_00720	ENOG4105BZU	Histidine kinase
HPC62_00790	ENOG41066KU	photosystem I subunit X
HPC62_00810	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HPC62_00825	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HPC62_00830	ENOG41084GG	50S ribosomal protein L33
HPC62_00835	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HPC62_00840	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_00850	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPC62_00880	ENOG4105CS2	ec 3.2.1.21
HPC62_00885	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HPC62_00900	ENOG4108VX5	3-methyladenine DNA glycosylase
HPC62_00945	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HPC62_00975	ENOG4105BZU	Histidine kinase
HPC62_01020	ENOG4108SGF	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_01055	ENOG4108K7V	UPF0284 protein
HPC62_01075	ENOG4105BZM	domain protein
HPC62_01085	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HPC62_01125	ENOG4105D7Z	glutathione synthase
HPC62_01140	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
HPC62_01150	ENOG4107TTD	cytosine deaminase
HPC62_01160	ENOG4105C7K	acetolactate synthase
HPC62_01205	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HPC62_01210	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HPC62_01220	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HPC62_01235	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
HPC62_01240	ENOG41090A1	ferritin
HPC62_01250	ENOG4105CEY	Amp-dependent synthetase and ligase
HPC62_01310	ENOG4105CSV	Glutaminase
HPC62_01315	ENOG4105D1F	ATP-binding protein
HPC62_01330	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HPC62_01345	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HPC62_01350	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HPC62_01365	ENOG4105C12	Phosphoribosylglycinamide synthetase
HPC62_01380	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HPC62_01395	ENOG4105KRS	Proteinase inhibitor
HPC62_01410	ENOG4105DZC	cytosine deaminase
HPC62_01440	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
HPC62_01445	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HPC62_01460	ENOG4108YRB	methyltransferase
HPC62_01465	ENOG4107YFT	Nadph-dependent fmn reductase
HPC62_01470	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPC62_01495	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HPC62_01505	ENOG4105CHH	sulfate transporter
HPC62_01510	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HPC62_01525	ENOG4107R73	Mate efflux family protein
HPC62_01550	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HPC62_01555	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HPC62_01560	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HPC62_01570	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HPC62_01600	ENOG4105E4C	Lytic transglycosylase catalytic
HPC62_01605	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HPC62_01615	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HPC62_01620	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HPC62_01630	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HPC62_01640	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_01650	ENOG4108IPT	Naphthoate synthase
HPC62_01665	ENOG4108J4B	Beta-lactamase
HPC62_01675	ENOG4105DR5	peptidase
HPC62_01720	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HPC62_01755	ENOG4105BZ1	(ABC) transporter
HPC62_01770	ENOG41060PQ	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
HPC62_01780	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HPC62_01795	ENOG4105BZU	Histidine kinase
HPC62_01805	ENOG4105BZU	Histidine kinase
HPC62_01825	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HPC62_01830	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HPC62_01855	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HPC62_01865	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HPC62_01875	ENOG4108HM4	ABC transporter
HPC62_01885	ENOG41080UQ	Transcriptional regulator
HPC62_01925	ENOG4105DGW	oligopeptidase A
HPC62_01945	ENOG4108SHN	Glycosyl transferase, family 2
HPC62_01960	ENOG4107YJ4	chain length determinant protein
HPC62_01985	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HPC62_02000	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HPC62_02050	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HPC62_02075	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HPC62_02190	ENOG41086B8	CoB-CoM heterodisulfide reductase
HPC62_02230	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
HPC62_02240	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_02290	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
HPC62_02295	ENOG4107T5V	SNARE associated Golgi
HPC62_02300	ENOG4107XR4	alpha beta
HPC62_02315	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HPC62_02320	ENOG4105CPC	Aldo Keto reductase
HPC62_02325	ENOG4105CAK	Cell division ATP-binding protein ftsE
HPC62_02355	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HPC62_02380	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HPC62_02425	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HPC62_02430	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HPC62_02445	ENOG4105C5F	glutamine synthetase
HPC62_02450	ENOG4105BZU	Histidine kinase
HPC62_02470	ENOG4105E1F	short-chain dehydrogenase reductase
HPC62_02480	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HPC62_02525	ENOG4105C26	Dehydrogenase
HPC62_02545	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
HPC62_02570	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HPC62_02580	ENOG4107VAM	peptidase, m28
HPC62_02585	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HPC62_02595	ENOG4105BZU	Histidine kinase
HPC62_02600	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_02605	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HPC62_02610	ENOG4105CVN	desaturase
HPC62_02640	ENOG4105C3M	thioredoxin reductase
HPC62_02650	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
HPC62_02655	ENOG4105ERH	Fumarylacetoacetate hydrolase
HPC62_02670	ENOG4105DRR	Transcriptional regulator, GntR family
HPC62_02675	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HPC62_02690	ENOG4105KC4	UPF0296 protein
HPC62_02710	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPC62_02715	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HPC62_02725	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HPC62_02730	ENOG4105I4A	GCN5-related N-acetyltransferase
HPC62_02765	ENOG41080UQ	Transcriptional regulator
HPC62_02775	ENOG4105D64	Mechanosensitive ion channel
HPC62_02795	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HPC62_02805	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HPC62_02820	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HPC62_02830	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HPC62_02840	ENOG4105D3R	alkyl hydroperoxide reductase
HPC62_02850	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HPC62_02855	ENOG4107RNI	Glucose 6-phosphate dehydrogenase effector OpcA
HPC62_02865	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
HPC62_02875	ENOG4108TCG	allophycocyanin beta subunit
HPC62_02885	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_02905	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
HPC62_02910	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HPC62_02925	ENOG4105CTK	cobaltochelatase, cobn subunit
HPC62_02935	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HPC62_02940	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HPC62_02945	ENOG4108MAQ	allophycocyanin alpha
HPC62_02955	ENOG4105W5K	Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity)
HPC62_03040	ENOG4106WTF	Glycosyl transferase, family 2
HPC62_03050	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HPC62_03065	ENOG4105PGM	cation diffusion facilitator family transporter
HPC62_03075	ENOG4105VN1	Heat shock protein
HPC62_03080	ENOG4105C9X	ppx gppa phosphatase
HPC62_03090	ENOG4106HWW	Acyltransferase family
HPC62_03100	ENOG4105CAS	nag kinase
HPC62_03115	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HPC62_03130	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
HPC62_03145	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HPC62_03155	ENOG4107RIQ	Sulfate adenylate transferase
HPC62_03165	ENOG4107FCW	Abortive infection protein
HPC62_03190	ENOG4105D6V	phycocyanin beta subunit
HPC62_03205	ENOG4108MZQ	phycobilisome linker polypeptide
HPC62_03210	ENOG4106DMB	CpcD phycobilisome linker domain protein
HPC62_03215	ENOG41078GB	pbs lyase
HPC62_03220	ENOG4108V9J	phycocyanobilin lyase
HPC62_03225	ENOG4106BTU	phycobilisome rod-core linker polypeptide
HPC62_03230	ENOG4106BTU	phycobilisome rod-core linker polypeptide
HPC62_03240	ENOG4106Q05	Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes (By similarity)
HPC62_03245	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HPC62_03260	ENOG4108UXN	response regulator
HPC62_03265	ENOG4105BZU	Histidine kinase
HPC62_03270	ENOG4105BZU	Histidine kinase
HPC62_03275	ENOG4105BZU	Histidine kinase
HPC62_03285	ENOG4107VRP	DNA repair exonuclease
HPC62_03300	ENOG4105C6X	Major Facilitator
HPC62_03325	ENOG4108PJD	permease
HPC62_03365	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPC62_03370	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HPC62_03385	ENOG4105J0U	photosystem II
HPC62_03400	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HPC62_03420	ENOG4105VGQ	Photosystem I subunit X
HPC62_03455	ENOG4105DX0	Hemolysin A
HPC62_03465	ENOG4105PFC	Transcriptional regulator
HPC62_03470	ENOG4108JGH	Tetr family transcriptional regulator
HPC62_03480	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HPC62_03500	ENOG4105DRP	amino acid AbC transporter
HPC62_03505	ENOG4105EZ7	amino acid ABC transporter
HPC62_03510	ENOG4107QXX	ABC transporter
HPC62_03545	ENOG4105C0H	protease
HPC62_03565	ENOG4107RH8	nuclease SbcCD subunit D
HPC62_03600	ENOG4105D3Q	Sugar transferase
HPC62_03640	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HPC62_03645	ENOG4108MRH	transcriptional regulatory protein
HPC62_03650	ENOG41083EU	50s ribosomal protein l28
HPC62_03730	ENOG41082AN	stage II sporulation protein
HPC62_03745	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HPC62_03750	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HPC62_03755	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HPC62_03775	ENOG4105D7N	magnesium and cobalt transport protein CorA
HPC62_03780	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HPC62_03800	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HPC62_03810	ENOG4107WDG	serine threonine protein kinase
HPC62_03820	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HPC62_03825	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HPC62_03830	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HPC62_03880	ENOG4108KMV	Glycosyl transferase (Group 1
HPC62_03905	ENOG4107Z3D	50S ribosomal protein l10
HPC62_03910	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HPC62_03915	ENOG4105JKW	Valine--pyruvate aminotransferase
HPC62_03930	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HPC62_03950	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HPC62_03960	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HPC62_03970	ENOG4105DFU	Cell wall formation (By similarity)
HPC62_03975	ENOG4105D4A	Cell wall formation (By similarity)
HPC62_04020	ENOG4105CDH	Citrulline--aspartate ligase
HPC62_04025	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_04035	ENOG4105EN6	Membrane
HPC62_04045	ENOG4107TS3	membrane protein, TerC
HPC62_04050	ENOG4105CFP	Peptidase U32
HPC62_04060	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HPC62_04065	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HPC62_04080	ENOG4107RFW	hydrolase family 57
HPC62_04120	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HPC62_04130	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HPC62_04135	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HPC62_04140	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HPC62_04150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPC62_04215	ENOG4108KS2	transglutaminase domain protein
HPC62_04220	ENOG4105CJN	penicillin-binding protein
HPC62_04225	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HPC62_04230	ENOG4105IJJ	transcriptional regulator, crp fnr family
HPC62_04245	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HPC62_04255	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HPC62_04270	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HPC62_04275	ENOG4105EET	magnesium chelatase
HPC62_04290	ENOG4105KVH	Transcriptional regulator
HPC62_04300	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
HPC62_04305	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPC62_04325	ENOG4105BZA	Phosphoglycerate kinase
HPC62_04330	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HPC62_04350	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HPC62_04385	ENOG4105WIA	photosystem II reaction center protein H
HPC62_04390	ENOG410686T	photosystem II reaction center protein N
HPC62_04410	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
HPC62_04420	ENOG4105DAA	L-lactate
HPC62_04440	ENOG4108R6K	riboflavin synthase, subunit alpha
HPC62_04445	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HPC62_04480	ENOG4107QHF	type ii secretion system protein e
HPC62_04485	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_04490	ENOG41088CC	tellurite resistance protein tehB
HPC62_04500	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HPC62_04515	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HPC62_04560	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HPC62_04565	ENOG4105D3G	Pseudouridine synthase
HPC62_04580	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HPC62_04595	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPC62_04600	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPC62_04615	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
HPC62_04630	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HPC62_04645	ENOG41084GC	stage II sporulation protein
HPC62_04650	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HPC62_04660	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HPC62_04670	ENOG4105CQC	Prephenate dehydratase
HPC62_04675	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HPC62_04680	ENOG4105VF7	tolerance protein
HPC62_04690	ENOG4108KXV	response regulator
HPC62_04700	ENOG4105D0C	transport protein
HPC62_04715	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HPC62_04720	ENOG41067HS	methyltransferase
HPC62_04730	ENOG4105C59	p-type ATPase
HPC62_04740	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HPC62_04750	ENOG4105CPQ	Dehydrogenase
HPC62_04755	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
HPC62_04760	ENOG4105DRS	transport system, permease
HPC62_04765	ENOG4105CPC	Aldo Keto reductase
HPC62_04775	ENOG4105E66	phosphoriboisomerase A
HPC62_04790	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HPC62_04800	ENOG4105DCI	Phosphohydrolase
HPC62_04805	ENOG4105CMI	transporter
HPC62_04810	ENOG4105CJ1	ABC, transporter
HPC62_04815	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPC62_04820	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
HPC62_04830	ENOG4105CXI	aluminum resistance protein
HPC62_04840	ENOG4105BZU	Histidine kinase
HPC62_04850	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPC62_04870	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HPC62_04905	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HPC62_04950	ENOG4105CVJ	phosphoglycerate mutase
HPC62_04960	ENOG4108JQC	penicillin-binding protein 1A
HPC62_04965	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HPC62_05040	ENOG4107RCV	ABC transporter, permease
HPC62_05055	ENOG4105C6K	Malic enzyme
HPC62_05060	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HPC62_05100	ENOG4105FDK	ABC transporter
HPC62_05105	ENOG4105FAV	ABC, transporter
HPC62_05150	ENOG41081FY	multiple antibiotic resistance (MarC)-related
HPC62_05175	ENOG4105D85	methylase
HPC62_05295	ENOG4105CNI	cell division protein FtsW
HPC62_05315	ENOG4107XWI	flavin reductase domain protein, FMN-binding
HPC62_05350	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_05360	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPC62_05365	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPC62_05375	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HPC62_05390	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HPC62_05415	ENOG4108S59	
HPC62_05425	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HPC62_05440	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPC62_05445	ENOG4107QZ7	Cellulose synthase catalytic subunit
HPC62_05460	ENOG4105E4F	Isochorismate synthase
HPC62_05475	ENOG4105W5Q	DNA repair protein (RadC
HPC62_05490	ENOG4105EWK	phytoene
HPC62_05495	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HPC62_05500	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HPC62_05530	ENOG4105DDQ	anthranilate synthase
HPC62_05550	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_05560	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
HPC62_05570	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HPC62_05595	ENOG4105CDA	abc transporter atp-binding protein
HPC62_05600	ENOG4105E5Q	amino acid AbC transporter
HPC62_05645	ENOG4105HHA	aminodeoxychorismate lyase
HPC62_05650	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HPC62_05660	ENOG41060PK	NIL
HPC62_05670	ENOG4107Z6A	sulfate abc transporter permease
HPC62_05675	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HPC62_05680	ENOG4105CKI	cobalamin synthesis protein
HPC62_05690	ENOG4105CFH	Aspartokinase
HPC62_05695	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HPC62_05715	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
HPC62_05750	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HPC62_05755	ENOG4105DFF	Rod shape-determining protein mreb
HPC62_05760	ENOG41080E3	single-stranded DNA-binding protein
HPC62_05770	ENOG4105C1Q	protoporphyrinogen oxidase
HPC62_05775	ENOG4105CJN	penicillin-binding protein
HPC62_05780	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_05785	ENOG4107RUE	extracellular solute-binding protein family 1
HPC62_05790	ENOG4105F38	ABC transporter, permease
HPC62_05795	ENOG4105D38	putrescine abc transporter
HPC62_05800	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HPC62_05835	ENOG4105CGZ	zinc metallopeptidase
HPC62_05850	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HPC62_05855	ENOG4108HW3	(ABC) transporter
HPC62_05865	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
HPC62_05880	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HPC62_05885	ENOG4105Q36	FHA domain containing protein
HPC62_05910	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPC62_05920	ENOG4105CPJ	photosystem II manganese-stabilizing
HPC62_05935	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_05960	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HPC62_06050	ENOG4105CVB	Vitamin K epoxide reductase
HPC62_06055	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HPC62_06070	ENOG4105E54	alpha-amylase
HPC62_06080	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPC62_06090	ENOG4105DWV	Homoserine O-trans-acetylase
HPC62_06095	ENOG4105CHR	reductase
HPC62_06140	ENOG4107WDG	serine threonine protein kinase
HPC62_06160	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HPC62_06185	ENOG4105C8M	UPF0272 protein
HPC62_06205	ENOG4105CHH	sulfate transporter
HPC62_06210	ENOG41082SX	arsR family transcriptional regulator
HPC62_06235	ENOG4107S17	Phosphate-binding protein
HPC62_06265	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
HPC62_06290	ENOG4107JDS	UPF0102 protein
HPC62_06330	ENOG4108Z66	YbaK ebsC protein
HPC62_06350	ENOG4105DXN	mazG family
HPC62_06360	ENOG4105E2K	Glycosyl transferase (Group 1
HPC62_06365	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HPC62_06380	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPC62_06420	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HPC62_06455	ENOG4105C3Q	Glycosyl transferase, family 2
HPC62_06495	ENOG4105CQB	FAD linked oxidase domain protein
HPC62_06555	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HPC62_06585	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_06590	ENOG4105GR3	Histidine kinase
HPC62_06635	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HPC62_06720	ENOG4108IJ8	ABC transporter
HPC62_06725	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HPC62_06750	ENOG4108JYK	Dehydrogenase
HPC62_06755	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_06780	ENOG4105BZU	Histidine kinase
HPC62_06845	ENOG4108TJN	glycosyl transferase group 1
HPC62_06860	ENOG4108RVA	ribokinase
HPC62_06865	ENOG4107QUY	Guanine deaminase
HPC62_06875	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
HPC62_06895	ENOG4105C2W	permease
HPC62_06900	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_06925	ENOG4107U9T	Pfam:Ribonuclease_BN
HPC62_06950	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HPC62_06990	ENOG4105CJN	penicillin-binding protein
HPC62_07010	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HPC62_07030	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HPC62_07035	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HPC62_07090	ENOG4105XEV	csbD-like
HPC62_07145	ENOG4105M08	Membrane
HPC62_07155	ENOG4105C8N	cysteinyl-tRNA synthetase
HPC62_07180	ENOG4105C0B	DNA polymerase III (alpha subunit)
HPC62_07190	ENOG4105CEY	Amp-dependent synthetase and ligase
HPC62_07200	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HPC62_07210	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HPC62_07225	ENOG4108HM4	ABC transporter
HPC62_07285	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HPC62_07295	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HPC62_07305	ENOG4105CMR	udp-glucose 4-epimerase
HPC62_07310	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_07315	ENOG4105D64	Mechanosensitive ion channel
HPC62_07350	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HPC62_07360	ENOG41086VY	Fic/DOC family
HPC62_07365	ENOG4105E1F	short-chain dehydrogenase reductase
HPC62_07375	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HPC62_07385	ENOG4107XFE	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HPC62_07410	ENOG4105JFG	SpoIID LytB domain protein
HPC62_07415	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
HPC62_07455	ENOG4105DB7	PHP domain protein
HPC62_07460	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HPC62_07470	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HPC62_07525	ENOG4105H3G	oxidoreductase
HPC62_07530	ENOG4105C26	Dehydrogenase
HPC62_07550	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HPC62_07555	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HPC62_07560	ENOG4105CDU	Replicative dna helicase
HPC62_07585	ENOG4105C5H	ABC transporter
HPC62_07625	ENOG4106ASF	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex (By similarity)
HPC62_07635	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HPC62_07645	ENOG4105ECY	inositol monophosphatase
HPC62_07705	ENOG410801B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HPC62_07750	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HPC62_07765	ENOG4108ZF3	Phosphatase
HPC62_07775	ENOG4105BZU	Histidine kinase
HPC62_07805	ENOG4105C8Q	Methyl-accepting chemotaxis
HPC62_07820	ENOG4108UNF	response regulator
HPC62_07835	ENOG4105C01	Dihydroxy-acid dehydratase
HPC62_07880	ENOG410848W	30S ribosomal protein S21
HPC62_07885	ENOG4105VFU	Rna-binding protein
HPC62_07890	ENOG4105CNG	UPF0061 protein
HPC62_07895	ENOG4105C7K	acetolactate synthase
HPC62_07905	ENOG4108E2B	had-superfamily hydrolase, subfamily iib
HPC62_07925	ENOG4105CBX	hi0933 family
HPC62_07935	ENOG4105E2K	Glycosyl transferase (Group 1
HPC62_07940	ENOG4105D3Q	Sugar transferase
HPC62_07990	ENOG4108TNP	
HPC62_07995	ENOG4105C9B	Cysteine desulfurase
HPC62_08015	ENOG4105PWN	phosphate abc transporter
HPC62_08045	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HPC62_08055	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HPC62_08060	ENOG4107ZYR	domain protein
HPC62_08065	ENOG4105CZN	Potassium uptake protein
HPC62_08095	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HPC62_08120	ENOG4105CXN	decarboxylase
HPC62_08125	ENOG4105ES5	Histidine kinase
HPC62_08135	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HPC62_08140	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HPC62_08165	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
HPC62_08210	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HPC62_08215	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HPC62_08225	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HPC62_08230	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_08240	ENOG4105CQB	FAD linked oxidase domain protein
HPC62_08245	ENOG4105BZU	Histidine kinase
HPC62_08250	ENOG4105CD8	aminopeptidase N
HPC62_08265	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPC62_08275	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HPC62_08295	ENOG4107XWB	Zinc finger, swim domain protein
HPC62_08360	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HPC62_08365	ENOG4105CMQ	Chloride channel
HPC62_08370	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_08405	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HPC62_08415	ENOG4105BZU	Histidine kinase
HPC62_08455	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
HPC62_08460	ENOG4105CBT	Fructose-1,6-bisphosphatase
HPC62_08485	ENOG4105BZU	Histidine kinase
HPC62_08490	ENOG4105DFK	Polyphosphate glucokinase
HPC62_08495	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HPC62_08505	ENOG4105BZ1	(ABC) transporter
HPC62_08525	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
HPC62_08555	ENOG4107RSS	Hydrogenase accessory protein HypB
HPC62_08585	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HPC62_08590	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HPC62_08595	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPC62_08600	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPC62_08610	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPC62_08620	ENOG4105PA3	atp synthase
HPC62_08625	ENOG4107SWE	Methyltransferase
HPC62_08635	ENOG4105EQK	-acetyltransferase
HPC62_08640	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HPC62_08660	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HPC62_08790	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HPC62_08845	ENOG4105CHM	Aminotransferase
HPC62_08855	ENOG4105CQM	Urea amidohydrolase subunit alpha
HPC62_08875	ENOG4105BZU	Histidine kinase
HPC62_08880	ENOG4105BZU	Histidine kinase
HPC62_08885	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPC62_08910	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HPC62_08920	ENOG4108IUZ	ABC transporter
HPC62_08965	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HPC62_08975	ENOG4105DBI	uridine monophosphokinase
HPC62_08985	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HPC62_09005	ENOG4105D3Q	Sugar transferase
HPC62_09130	ENOG41082AN	stage II sporulation protein
HPC62_09145	ENOG4105EMN	RNA polymerase sigma factor
HPC62_09150	ENOG4105C72	UPF0176 protein
HPC62_09160	ENOG4105CNF	WD-40 repeat protein
HPC62_09165	ENOG4105DIH	basic membrane
HPC62_09170	ENOG4105UIB	(ABC) transporter
HPC62_09185	ENOG4108JQ9	ABC transporter
HPC62_09195	ENOG4105C5S	asparaginyl-tRNA synthetase
HPC62_09250	ENOG4105KME	endoribonuclease L-psp
HPC62_09255	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HPC62_09260	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HPC62_09285	ENOG4106TD9	Diguanylate cyclase
HPC62_09335	ENOG4105CJW	magnesium transporter
HPC62_09340	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HPC62_09345	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HPC62_09425	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HPC62_09430	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HPC62_09445	ENOG4105CHH	sulfate transporter
HPC62_09500	ENOG4105D5K	Hemolysin activator protein
HPC62_09515	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
HPC62_09530	ENOG4105BZU	Histidine kinase
HPC62_09550	ENOG4105CUT	histidyl-tRNA synthetase
HPC62_09560	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPC62_09575	ENOG4106PMH	Extracellular solute-binding protein family 3
HPC62_09580	ENOG4105E5Q	amino acid AbC transporter
HPC62_09625	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HPC62_09650	ENOG4105CRK	lysyL-tRNA synthetase
HPC62_09655	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HPC62_09735	ENOG4105GVR	general secretion pathway protein D
HPC62_09740	ENOG4105K70	DNA-binding protein
HPC62_09745	ENOG4107QZB	decarboxylase
HPC62_09750	ENOG4105C7Z	Conserved Protein
HPC62_09765	ENOG4106PMH	Extracellular solute-binding protein family 3
HPC62_09780	ENOG4105BZU	Histidine kinase
HPC62_09785	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HPC62_09795	ENOG4105C75	arginyL-tRNA synthetase
HPC62_09810	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HPC62_09830	ENOG4105BZU	Histidine kinase
HPC62_09835	ENOG4105CTK	cobaltochelatase, cobn subunit
HPC62_09865	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
HPC62_09890	ENOG4105BZU	Histidine kinase
HPC62_09895	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HPC62_09920	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HPC62_09950	ENOG4105E6M	Sulphatase-modifying factor protein
HPC62_09970	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HPC62_10000	ENOG41061MV	Arylsulfatase
HPC62_10030	ENOG4105D74	hydrolase
HPC62_10035	ENOG4105E6M	Sulphatase-modifying factor protein
HPC62_10055	ENOG4108JQC	penicillin-binding protein 1A
HPC62_10075	ENOG4105K8N	protein family UPF0079, ATPase
HPC62_10080	ENOG4105C6E	dna polymerase iii
HPC62_10115	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HPC62_10125	ENOG4105DHP	deoxycytidine triphosphate deaminase
HPC62_10160	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HPC62_10165	ENOG4105C6E	dna polymerase iii
HPC62_10170	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HPC62_10220	ENOG4105DA5	(ABC) transporter
HPC62_10235	ENOG4105DGU	Histone deacetylase
HPC62_10260	ENOG4107XZ0	Peptidase M50
HPC62_10270	ENOG4105BZU	Histidine kinase
HPC62_10275	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_10295	ENOG4107WJM	-acetyltransferase
HPC62_10305	ENOG4105CSR	polyphosphate kinase 2
HPC62_10315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_10320	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HPC62_10325	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HPC62_10335	ENOG4105CEY	Amp-dependent synthetase and ligase
HPC62_10350	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HPC62_10360	ENOG4105DVK	Precorrin-2 c20-methyltransferase
HPC62_10365	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HPC62_10390	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HPC62_10400	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HPC62_10415	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_10435	ENOG4105C8B	TIGR00159 family
HPC62_10445	ENOG410801F	ribosomal-protein-alanine acetyltransferase
HPC62_10460	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HPC62_10485	ENOG41072GX	Peptidase M22 Glycoprotease
HPC62_10540	ENOG4105E0C	molybdate abc transporter
HPC62_10545	ENOG4108IJ6	ABC transporter
HPC62_10550	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HPC62_10570	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HPC62_10575	ENOG4107XM9	(LipO)protein
HPC62_10595	ENOG4105BZF	Glycosyl transferase (Group 1
HPC62_10630	ENOG4107S73	homocitrate synthase
HPC62_10635	ENOG4108JA1	polyketide synthase
HPC62_10650	ENOG4105CHR	reductase
HPC62_10685	ENOG41063NY	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HPC62_10690	ENOG4108062	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HPC62_10695	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HPC62_10705	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HPC62_10710	ENOG4105C0Z	ABC transporter
HPC62_10750	ENOG4105C31	Tryptophanyl-tRNA synthetase
HPC62_10760	ENOG4105E0X	reductase
HPC62_10765	ENOG4105EB3	Histidine kinase
HPC62_10770	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_10795	ENOG4105D4Y	metalloprotease
HPC62_10800	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HPC62_10810	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HPC62_10820	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HPC62_10825	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HPC62_10885	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HPC62_10905	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HPC62_10955	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPC62_11030	ENOG4105CQR	helicase
HPC62_11040	ENOG4105C8T	Leucyl-tRNA synthetase
HPC62_11055	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HPC62_11065	ENOG41085FC	arsR family transcriptional regulator
HPC62_11070	ENOG4105C1J	atp-dependent rna helicase
HPC62_11075	ENOG41063SB	peptidase
HPC62_11085	ENOG4108YXU	transcriptional regulator AsnC family
HPC62_11090	ENOG4105D0M	Protease HtpX homolog
HPC62_11095	ENOG4105C8Y	Acetylornithine aminotransferase
HPC62_11130	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HPC62_11220	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HPC62_11225	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
HPC62_11250	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HPC62_11295	ENOG4105MPN	Membrane
HPC62_11310	ENOG4105BZU	Histidine kinase
HPC62_11360	ENOG4105DCF	alanine dehydrogenase
HPC62_11370	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HPC62_11380	ENOG4105BZU	Histidine kinase
HPC62_11390	ENOG4107E2E	PKHD-type hydroxylase
HPC62_11440	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HPC62_11520	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HPC62_11530	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HPC62_11535	ENOG4108VCT	Sulfite exporter TauE/SafE
HPC62_11555	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
HPC62_11580	ENOG41088CC	tellurite resistance protein tehB
HPC62_11585	ENOG4105ND9	Nitrogenase-associated protein
HPC62_11590	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HPC62_11630	ENOG4105D7W	serine acetyltransferase
HPC62_11655	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
HPC62_11685	ENOG4108UR2	Nitrogen fixation protein NifX
HPC62_11690	ENOG4108VQE	nitrogen fixation protein
HPC62_11695	ENOG4108NWW	ferritin dps family protein
HPC62_11700	ENOG4107S73	homocitrate synthase
HPC62_11775	ENOG4105C0D	helicase
HPC62_11860	ENOG4105BZU	Histidine kinase
HPC62_11870	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HPC62_11880	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HPC62_11885	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HPC62_11890	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
HPC62_11905	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HPC62_11910	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
HPC62_11920	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HPC62_11945	ENOG4107R0E	Glycosyl transferase, family 2
HPC62_11965	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HPC62_11975	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HPC62_11980	ENOG4105CJ1	ABC, transporter
HPC62_11985	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
HPC62_11990	ENOG4105F32	YngK protein
HPC62_12000	ENOG4105CSR	polyphosphate kinase 2
HPC62_12005	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
HPC62_12030	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HPC62_12040	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HPC62_12045	ENOG4105EUJ	GTP cyclohydrolase i
HPC62_12070	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_12075	ENOG41076QQ	Glycosyl transferase, family 2
HPC62_12095	ENOG4108JJA	ABC, transporter
HPC62_12145	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HPC62_12195	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HPC62_12205	ENOG4108SKZ	Patatin-like phospholipase
HPC62_12215	ENOG4107WZZ	SMC domain protein
HPC62_12230	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HPC62_12240	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HPC62_12265	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HPC62_12270	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPC62_12275	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HPC62_12295	ENOG4106F1P	AAA ATPase, central domain protein
HPC62_12305	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
HPC62_12335	ENOG4108E1C	hydrolase
HPC62_12340	ENOG4105CNW	domain protein
HPC62_12355	ENOG4105CNW	domain protein
HPC62_12365	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_12420	ENOG4105E6M	Sulphatase-modifying factor protein
HPC62_12445	ENOG4107QPR	SAICAR synthetase
HPC62_12495	ENOG4105MSA	Photosystem II reaction center W protein
HPC62_12500	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
HPC62_12555	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HPC62_12575	ENOG4105DAY	polysaccharide export protein
HPC62_12615	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HPC62_12625	ENOG4105N6Y	Thioredoxin
HPC62_12645	ENOG4105C5I	Dehydrogenase
HPC62_12655	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
HPC62_12660	ENOG4105D5U	fad dependent oxidoreductase
HPC62_12665	ENOG4105CMR	udp-glucose 4-epimerase
HPC62_12670	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HPC62_12680	ENOG4105DAY	polysaccharide export protein
HPC62_12715	ENOG4105U3E	Transcriptional regulator
HPC62_12725	ENOG4105D2N	Aldolase
HPC62_12730	ENOG4108JJB	ABC transporter
HPC62_12735	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HPC62_12745	ENOG4108IJ9	(ABC) transporter
HPC62_12755	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HPC62_12765	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_12770	ENOG4105NZG	Ferredoxin
HPC62_12785	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HPC62_12790	ENOG4105D0M	Protease HtpX homolog
HPC62_12795	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HPC62_12830	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPC62_12835	ENOG4107QHF	type ii secretion system protein e
HPC62_12840	ENOG4105CZX	twitching motility protein
HPC62_12910	ENOG4105Y3U	Transglycosylase-associated protein
HPC62_12940	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HPC62_12960	ENOG4108IYU	L-aspartate oxidase
HPC62_12980	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HPC62_13030	ENOG4108IUW	ABC transporter
HPC62_13040	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HPC62_13050	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HPC62_13075	ENOG4105BZ1	(ABC) transporter
HPC62_13080	ENOG4105K64	Glycosyl transferase, family 2
HPC62_13085	ENOG4105K64	Glycosyl transferase, family 2
HPC62_13090	ENOG4105CPK	Glycosyl transferase (Group 1
HPC62_13115	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HPC62_13135	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HPC62_13145	ENOG4106CD9	glycosyl transferase group 1
HPC62_13150	ENOG4108WF2	Metal Dependent Phosphohydrolase
HPC62_13175	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HPC62_13185	ENOG4105BZ1	(ABC) transporter
HPC62_13195	ENOG4105H63	Glycosyl transferase, family 2
HPC62_13220	ENOG4107T8Q	Glycosyl transferase (Group 1
HPC62_13225	ENOG4105DAY	polysaccharide export protein
HPC62_13230	ENOG4107YJ4	chain length determinant protein
HPC62_13255	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HPC62_13265	ENOG4107VAM	peptidase, m28
HPC62_13270	ENOG4105CPC	Aldo Keto reductase
HPC62_13280	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HPC62_13330	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_13335	ENOG4107T8Q	Glycosyl transferase (Group 1
HPC62_13340	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_13345	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_13355	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_13375	ENOG4105BZ1	(ABC) transporter
HPC62_13380	ENOG4107YJ4	chain length determinant protein
HPC62_13420	ENOG4108JQ6	ABC transporter
HPC62_13430	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HPC62_13435	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HPC62_13455	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
HPC62_13460	ENOG4105DR5	peptidase
HPC62_13495	ENOG4107R21	site-determining protein
HPC62_13505	ENOG4105BZU	Histidine kinase
HPC62_13515	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
HPC62_13520	ENOG4105EHU	Circadian clock protein KaiC
HPC62_13540	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HPC62_13545	ENOG4105BZU	Histidine kinase
HPC62_13590	ENOG4105CD3	dihydroorotase
HPC62_13605	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HPC62_13610	ENOG4105CIK	Amidinotransferase
HPC62_13660	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HPC62_13670	ENOG4105E2K	Glycosyl transferase (Group 1
HPC62_13675	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_13705	ENOG4105EYW	Ion transport protein
HPC62_13765	ENOG4105CVJ	phosphoglycerate mutase
HPC62_13780	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HPC62_13815	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HPC62_13820	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HPC62_13835	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HPC62_13880	ENOG4105D0M	Protease HtpX homolog
HPC62_13895	ENOG4105BZU	Histidine kinase
HPC62_13950	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
HPC62_14000	ENOG41065W4	chlorophyll a b binding light harvesting protein
HPC62_14005	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HPC62_14020	ENOG4105DSE	periplasmic solute binding protein
HPC62_14075	ENOG4105F32	YngK protein
HPC62_14090	ENOG4105D9R	oxidoreductase
HPC62_14095	ENOG4105ETX	regulatoR
HPC62_14110	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HPC62_14130	ENOG4105K63	Thioredoxin
HPC62_14135	ENOG4105D49	3-dehydroquinate synthase
HPC62_14155	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPC62_14160	ENOG4105CJW	magnesium transporter
HPC62_14170	ENOG4107ZYJ	bioY protein
HPC62_14175	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HPC62_14180	ENOG410828V	rubredoxin
HPC62_14195	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
HPC62_14265	ENOG4105BZU	Histidine kinase
HPC62_14275	ENOG4105D9N	nucleoside
HPC62_14280	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_14290	ENOG4105BZU	Histidine kinase
HPC62_14295	ENOG4108Z6B	deaminase
HPC62_14300	ENOG4105C3M	thioredoxin reductase
HPC62_14340	ENOG4105BZU	Histidine kinase
HPC62_14365	ENOG4107E2E	PKHD-type hydroxylase
HPC62_14370	ENOG4108Z0R	Transferase
HPC62_14385	ENOG4108HMN	Caspase domain
HPC62_14390	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HPC62_14395	ENOG4105CMR	udp-glucose 4-epimerase
HPC62_14440	ENOG4108SHN	Glycosyl transferase, family 2
HPC62_14450	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HPC62_14470	ENOG4108SHN	Glycosyl transferase, family 2
HPC62_14475	ENOG41064K2	Hepn domain protein
HPC62_14510	ENOG41082AN	stage II sporulation protein
HPC62_14545	ENOG4105D52	delta-aminolevulinic acid dehydratase
HPC62_14555	ENOG4105EMU	Dehydrogenase
HPC62_14615	ENOG4105D5K	Hemolysin activator protein
HPC62_14630	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HPC62_14635	ENOG4108MNP	Glycoprotein polysaccharide metabolism
HPC62_14640	ENOG4108VHT	MarR family transcriptional regulator
HPC62_14665	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HPC62_14710	ENOG4105D9R	oxidoreductase
HPC62_14725	ENOG4108UNF	response regulator
HPC62_14750	ENOG4107RCI	amp-dependent synthetase and ligase
HPC62_14755	ENOG4107T9Q	phosphonate abc transporter
HPC62_14760	ENOG4105D5T	phosphonate abc transporter
HPC62_14770	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
HPC62_14775	ENOG4105CZX	twitching motility protein
HPC62_14780	ENOG4107S5T	Carbohydrate kinase
HPC62_14800	ENOG4105EMU	Dehydrogenase
HPC62_14810	ENOG4105FE1	phytoene synthase
HPC62_14820	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HPC62_14825	ENOG4105C5F	glutamine synthetase
HPC62_14945	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
HPC62_14950	ENOG4108RCM	Nitroreductase
HPC62_15010	ENOG4105CP9	extracellular ligand-binding receptor
HPC62_15080	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HPC62_15095	ENOG4105C5H	ABC transporter
HPC62_15115	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
HPC62_15120	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HPC62_15160	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HPC62_15165	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HPC62_15195	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
HPC62_15200	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_15215	ENOG4105BZU	Histidine kinase
HPC62_15280	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HPC62_15330	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HPC62_15395	ENOG4105BZU	Histidine kinase
HPC62_15430	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HPC62_15450	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
HPC62_15460	ENOG4105BZ1	(ABC) transporter
HPC62_15510	ENOG41088PD	hydrolase
HPC62_15520	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HPC62_15555	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HPC62_15630	ENOG4105WH1	Two component transcriptional regulator luxr family
HPC62_15635	ENOG4105BZU	Histidine kinase
HPC62_15660	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HPC62_15665	ENOG4105C5I	Dehydrogenase
HPC62_15670	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HPC62_15690	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HPC62_15720	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_15725	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HPC62_15740	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HPC62_15800	ENOG4105C8U	phosphate abc transporter
HPC62_15805	ENOG4105E2Z	phosphate ABC transporter (Permease
HPC62_15810	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HPC62_15835	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HPC62_15865	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HPC62_15905	ENOG4105X25	
HPC62_15920	ENOG4105BZU	Histidine kinase
HPC62_15925	ENOG4105WH1	Two component transcriptional regulator luxr family
HPC62_15945	ENOG41086BQ	Protein CrcB homolog
HPC62_15960	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HPC62_15975	ENOG4105C2I	pirin domain protein
HPC62_15985	ENOG4105KVH	Transcriptional regulator
HPC62_16045	ENOG4105CJ1	ABC, transporter
HPC62_16050	ENOG4108JUA	Transcriptional regulator
HPC62_16055	ENOG4107YCR	Transcriptional regulator, ARSR family
HPC62_16070	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HPC62_16090	ENOG4105C26	Dehydrogenase
HPC62_16095	ENOG4105C5F	glutamine synthetase
HPC62_16100	ENOG4105NVB	glycoside hydrolase, family 19
HPC62_16110	ENOG4107QRT	dEAD DEAH box helicase
HPC62_16240	ENOG4105CDA	abc transporter atp-binding protein
HPC62_16265	ENOG4105DR4	Methyltransferase
HPC62_16290	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HPC62_16315	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HPC62_16330	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HPC62_16355	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HPC62_16360	ENOG4105PGM	cation diffusion facilitator family transporter
HPC62_16385	ENOG4107T3P	ABC, transporter
HPC62_16455	ENOG4107QRP	cobalamin biosynthesis protein CobW
HPC62_16485	ENOG4105D8X	mechanosensitive ion channel
HPC62_16510	ENOG4108V5V	Serine Threonine protein kinase
HPC62_16540	ENOG4107QN2	dihydrolipoyl dehydrogenase
HPC62_16585	ENOG4105VN1	Heat shock protein
HPC62_16630	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HPC62_16640	ENOG4108Q5Y	Membrane
HPC62_16645	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HPC62_16675	ENOG4107VC8	ATP cone domain protein
HPC62_16740	ENOG4107Y9U	Membrane
HPC62_16750	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HPC62_16760	ENOG4105ETX	regulatoR
HPC62_16790	ENOG4105KI2	Urea amidohydrolase subunit beta
HPC62_16795	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HPC62_16800	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HPC62_16810	ENOG4105CRE	cytochrome C
HPC62_16825	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
HPC62_16880	ENOG4108JQ6	ABC transporter
HPC62_16885	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPC62_16900	ENOG4107RAQ	aminopeptidase
HPC62_16915	ENOG4105CD2	stage iii sporulation protein aa
HPC62_16930	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
HPC62_16935	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HPC62_16940	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HPC62_16960	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
HPC62_16970	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HPC62_17050	ENOG4105BZU	Histidine kinase
HPC62_17055	ENOG4105VFU	Rna-binding protein
HPC62_17070	ENOG4107QZ7	Cellulose synthase catalytic subunit
HPC62_17080	ENOG4105M3Z	response regulator
HPC62_17150	ENOG4105DRS	transport system, permease
HPC62_17180	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HPC62_17190	ENOG4105YVZ	photosystem II
HPC62_17200	ENOG4106DDF	Photosystem II reaction center protein M
HPC62_17205	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HPC62_17210	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HPC62_17215	ENOG4105C19	ABC transporter
HPC62_17220	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HPC62_17235	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_17250	ENOG4105M0M	Tetracycline resistance protein
HPC62_17260	ENOG4107EPV	Aminotransferase class V
HPC62_17285	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HPC62_17320	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HPC62_17345	ENOG41083MR	nifu domain-containing protein
HPC62_17360	ENOG4107R7Y	intracellular protease Pfpi family
HPC62_17405	ENOG4105BZU	Histidine kinase
HPC62_17415	ENOG4105BZU	Histidine kinase
HPC62_17430	ENOG4107QKW	extracellular solute-binding protein family 1
HPC62_17450	ENOG4105WH1	Two component transcriptional regulator luxr family
HPC62_17470	ENOG4105C85	amino acid
HPC62_17505	ENOG4107VUB	phosphate binding protein
HPC62_17515	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
HPC62_17520	ENOG4105CHV	Transcription elongation factor NusA
HPC62_17545	ENOG4105EYH	Exonuclease
HPC62_17560	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HPC62_17580	ENOG4106R7G	Glycoside hydrolase family 5
HPC62_17595	ENOG4107SM8	Adenylate Guanylate cyclase
HPC62_17620	ENOG4105JNK	Glycosyl transferase (Group 1
HPC62_17625	ENOG4105CPK	Glycosyl transferase (Group 1
HPC62_17650	ENOG4105CEV	competence damage-inducible protein
HPC62_17655	ENOG4105ESV	Glycosyl transferase, family 4
HPC62_17675	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPC62_17710	ENOG4105C0D	helicase
HPC62_17715	ENOG4107TCE	N-acetyltransferase
HPC62_17735	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HPC62_17740	ENOG4105D0M	Protease HtpX homolog
HPC62_17755	ENOG4105VXP	Protein of unknown function DUF86
HPC62_17760	ENOG4108Y85	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_17765	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HPC62_17810	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HPC62_17815	ENOG4107QN2	dihydrolipoyl dehydrogenase
HPC62_17820	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HPC62_17830	ENOG4105BZ1	(ABC) transporter
HPC62_17850	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
HPC62_17855	ENOG4105E9X	Photosystem II 44 kDa subunit reaction center protein
HPC62_17860	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HPC62_17885	ENOG4105C8Y	Acetylornithine aminotransferase
HPC62_17890	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HPC62_17895	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HPC62_17920	ENOG4107TVC	Glycosyl transferase, family 2
HPC62_17945	ENOG4107RIX	inner membrane protein translocase component YidC
HPC62_17960	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPC62_17985	ENOG4108R85	Short chain dehydrogenase
HPC62_18050	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HPC62_18055	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HPC62_18060	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_18065	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HPC62_18085	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_18105	ENOG4107RAQ	aminopeptidase
HPC62_18115	ENOG4107KHP	This protein is a component of the reaction center of photosystem II (By similarity)
HPC62_18140	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HPC62_18145	ENOG4105BZU	Histidine kinase
HPC62_18155	ENOG4105BZU	Histidine kinase
HPC62_18160	ENOG4105WH1	Two component transcriptional regulator luxr family
HPC62_18165	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HPC62_18175	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HPC62_18190	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HPC62_18195	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HPC62_18225	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HPC62_18230	ENOG4108IUK	alpha amylase, catalytic
HPC62_18245	ENOG4105E09	nadh pyrophosphatase
HPC62_18275	ENOG4105FR1	rard protein
HPC62_18305	ENOG4105BZU	Histidine kinase
HPC62_18310	ENOG4105E4C	Lytic transglycosylase catalytic
HPC62_18315	ENOG4105BZU	Histidine kinase
HPC62_18370	ENOG4105CVA	phosphate
HPC62_18420	ENOG4105CPQ	Dehydrogenase
HPC62_18425	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HPC62_18440	ENOG4105C37	(CBS) domain
HPC62_18450	ENOG4108ZCU	PPIases accelerate the folding of proteins
HPC62_18455	ENOG4105D65	subunit l
HPC62_18460	ENOG4105C8S	subunit m
HPC62_18480	ENOG4105BZ8	glutamate synthase
HPC62_18495	ENOG4105D8X	mechanosensitive ion channel
HPC62_18510	ENOG4106WTF	Glycosyl transferase, family 2
HPC62_18515	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HPC62_18545	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
HPC62_18550	ENOG4105M3Z	response regulator
HPC62_18570	ENOG4105CEN	a g-specific adenine glycosylase
HPC62_18585	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_18590	ENOG4107R0W	ABC transporter
HPC62_18595	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HPC62_18610	ENOG4106UY4	Inherit from COG: Scp-like extracellular
HPC62_18635	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPC62_18665	ENOG4105D0M	Protease HtpX homolog
HPC62_18685	ENOG4105ETX	regulatoR
HPC62_18695	ENOG41061H0	Monooxygenase
HPC62_18700	ENOG4105VT2	5-hydroxyisourate hydrolase
HPC62_18710	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HPC62_18715	ENOG4105F1A	Pyruvate formate-lyase
HPC62_18730	ENOG4105C0A	alcohol dehydrogenase
HPC62_18765	ENOG4105CHM	Aminotransferase
HPC62_18805	ENOG4105CE4	GlcNAc 6-P deacetylase
HPC62_18810	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HPC62_18815	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HPC62_18840	ENOG4105BZU	Histidine kinase
HPC62_18850	ENOG4108NWW	ferritin dps family protein
HPC62_18855	ENOG4105FFC	UPF0187 protein
HPC62_18860	ENOG4107RSM	transcriptional regulator
HPC62_18900	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HPC62_18925	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HPC62_18930	ENOG4105D0M	Protease HtpX homolog
HPC62_18970	ENOG4105C8S	subunit m
HPC62_18980	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
HPC62_18985	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HPC62_18990	ENOG4105MXK	Carbon dioxide concentrating mechanism protein
HPC62_19005	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_19015	ENOG4108ZF3	Phosphatase
HPC62_19045	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HPC62_19095	ENOG4105D0M	Protease HtpX homolog
HPC62_19125	ENOG4105DTQ	mandelate racemase muconate lactonizing
HPC62_19130	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HPC62_19135	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HPC62_19140	ENOG4105DKP	glycosyl transferase, family 9
HPC62_19145	ENOG4105CYM	Glutathione S-transferase
HPC62_19150	ENOG4108Z6Z	Transcriptional regulator
HPC62_19185	ENOG4105DFE	Dna adenine methylase
HPC62_19235	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HPC62_19245	ENOG4105F95	Monooxygenase
HPC62_19250	ENOG4105C5F	glutamine synthetase
HPC62_19275	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HPC62_19315	ENOG4105MSA	Photosystem II reaction center W protein
HPC62_19320	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HPC62_19365	ENOG4108W6I	photosystem I reaction center protein subunit XI
HPC62_19385	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPC62_19395	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HPC62_19415	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HPC62_19440	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HPC62_19445	ENOG4105C3M	thioredoxin reductase
HPC62_19450	ENOG4105BZU	Histidine kinase
HPC62_19455	ENOG4105CJP	fad dependent oxidoreductase
HPC62_19460	ENOG4105KZX	Pterin carbinolamine dehydratase
HPC62_19470	ENOG4105D81	ABC transporter, permease
HPC62_19480	ENOG4105D7T	ABC transporter
HPC62_19485	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HPC62_19500	ENOG4105DJZ	UPF0182 protein
HPC62_19515	ENOG4106855	Competence protein
HPC62_19520	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HPC62_19580	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HPC62_19590	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HPC62_19600	ENOG4106AST	May help in the organization of the PsaE and PsaF subunits (By similarity)
HPC62_19610	ENOG4105CI1	PTS System
HPC62_19615	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HPC62_19620	ENOG4108ZFD	Antibiotic biosynthesis monooxygenase
HPC62_19630	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPC62_19640	ENOG4108KGH	TRANSCRIPTIONal
HPC62_19715	ENOG4107SGM	protein serine threonine phosphatase
HPC62_19740	ENOG4108KQJ	Type 11 methyltransferase
HPC62_19750	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HPC62_19760	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
HPC62_19770	ENOG4106MP8	UPF0754 membrane protein
HPC62_19800	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HPC62_19820	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HPC62_19845	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
HPC62_19850	ENOG4107T0X	DNA ligase
HPC62_19855	ENOG4105BZU	Histidine kinase
HPC62_19860	ENOG4108Z86	Glutamine amidotransferase
HPC62_19865	ENOG4105CHR	reductase
HPC62_19880	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HPC62_19885	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HPC62_19890	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HPC62_19895	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HPC62_19905	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HPC62_19940	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HPC62_19955	ENOG4107QJE	Chromosome Partitioning Protein
HPC62_19980	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
HPC62_19995	ENOG4105C0P	Mg chelatase subunit ChlI
HPC62_20010	ENOG4108WPJ	Ferritin-like domain
HPC62_20035	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HPC62_20040	ENOG4105D44	asparaginase
HPC62_20065	ENOG41081UC	Inherit from COG: Competence protein
HPC62_20075	ENOG4106855	Competence protein
HPC62_20085	ENOG4105E4R	Precorrin-3B C17-methyltransferase
HPC62_20095	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HPC62_20125	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HPC62_20135	ENOG4105BZU	Histidine kinase
HPC62_20145	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
HPC62_20175	ENOG4108KXV	response regulator
HPC62_20205	ENOG4108IJ6	ABC transporter
HPC62_20210	ENOG4105CHW	UPF0052 protein
HPC62_20215	ENOG4105D7K	pfkb domain protein
HPC62_20245	ENOG4105CRQ	synthase (Component I)
HPC62_20295	ENOG4108VPT	UPF0234 protein
HPC62_20315	ENOG4105BZF	Glycosyl transferase (Group 1
HPC62_20325	ENOG41080UQ	Transcriptional regulator
HPC62_20340	ENOG4105DAY	polysaccharide export protein
HPC62_20345	ENOG4107YJ4	chain length determinant protein
HPC62_20360	ENOG4107T8Q	Glycosyl transferase (Group 1
HPC62_20370	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HPC62_20375	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HPC62_20380	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
HPC62_20385	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HPC62_20405	ENOG4105BZ1	(ABC) transporter
HPC62_20415	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HPC62_20440	ENOG4107UQD	Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity)
HPC62_20460	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HPC62_20475	ENOG4105BZU	Histidine kinase
HPC62_20505	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
HPC62_20520	ENOG4105E0R	Deoxyhypusine synthase
HPC62_20535	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HPC62_20540	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPC62_20560	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPC62_20570	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_20580	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HPC62_20600	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HPC62_20620	ENOG4105K64	Glycosyl transferase, family 2
HPC62_20625	ENOG4105DXI	Major Facilitator superfamily
HPC62_20650	ENOG4107QJE	Chromosome Partitioning Protein
HPC62_20690	ENOG4108UHU	Aldolase
HPC62_20725	ENOG4105CFG	Acts as a chaperone (By similarity)
HPC62_20735	ENOG4105EUB	pirin domain protein
HPC62_20850	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HPC62_20865	ENOG4105D9N	nucleoside
HPC62_20875	ENOG4105CJ3	phosphate transporter
HPC62_20910	ENOG41061MD	high-affinity nickel-transporter
HPC62_20925	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_20950	ENOG4107Z8V	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HPC62_20960	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HPC62_20965	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HPC62_20970	ENOG4105XCI	PucC protein
HPC62_20985	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HPC62_20990	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPC62_21015	ENOG4105CMG	Carbohydrate kinase
HPC62_21035	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HPC62_21045	ENOG4105EEK	Polypeptide
HPC62_21075	ENOG4105CKK	Glycosyl transferase, family 2
HPC62_21090	ENOG4108DN8	FAD dependent oxidoreductase
HPC62_21095	ENOG4108Z2U	ureidoglycolate hydrolase
HPC62_21100	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HPC62_21115	ENOG4105KHC	sulfurtransferase
HPC62_21120	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HPC62_21175	ENOG4105C8S	subunit m
HPC62_21180	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HPC62_21245	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HPC62_21280	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HPC62_21310	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HPC62_21340	ENOG41082HT	Binds the 23S rRNA (By similarity)
HPC62_21355	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HPC62_21360	ENOG4108ZT0	50S ribosomal protein l17
HPC62_21365	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPC62_21370	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HPC62_21395	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HPC62_21400	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HPC62_21405	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HPC62_21410	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HPC62_21420	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HPC62_21425	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPC62_21450	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HPC62_21455	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HPC62_21460	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HPC62_21470	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPC62_21480	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HPC62_21485	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HPC62_21495	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HPC62_21500	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_21505	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HPC62_21510	ENOG4105DR5	peptidase
HPC62_21525	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HPC62_21530	ENOG4105W8H	transhydrogenase (subunit alpha
HPC62_21535	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HPC62_21555	ENOG4105CC5	ABC transporter
HPC62_21560	ENOG4105DIK	(ABC) transporter
HPC62_21565	ENOG4105DSE	periplasmic solute binding protein
HPC62_21575	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
HPC62_21590	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
HPC62_21605	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_21625	ENOG4105BZU	Histidine kinase
HPC62_21630	ENOG4105ETU	transcriptional activator (TenA
HPC62_21670	ENOG4105BZU	Histidine kinase
HPC62_21690	ENOG4108JQC	penicillin-binding protein 1A
HPC62_21700	ENOG4105DWF	phosphomethylpyrimidine kinase
HPC62_21735	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HPC62_21740	ENOG4105CT1	(ABC) transporter
HPC62_21745	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HPC62_21770	ENOG4108Z61	cytochrome c-550
HPC62_21780	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HPC62_21795	ENOG4107RA4	Glycosyl transferase (Group 1
HPC62_21810	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
HPC62_21820	ENOG4105K8R	UPF0145 protein
HPC62_21825	ENOG4108IV0	ABC, transporter
HPC62_21830	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPC62_21835	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HPC62_21840	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_21935	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HPC62_22005	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPC62_22020	ENOG4108IV0	ABC, transporter
HPC62_22025	ENOG4105C0Z	ABC transporter
HPC62_22035	ENOG4105C32	Amino acid ABC transporter (Permease)
HPC62_22040	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HPC62_22065	ENOG4105BZU	Histidine kinase
HPC62_22070	ENOG4108ZAF	Molybdopterin
HPC62_22075	ENOG4105CGH	5'-nucleotidase
HPC62_22090	ENOG4105C8S	subunit m
HPC62_22095	ENOG4107XWZ	ferric uptake regulator
HPC62_22110	ENOG41067XK	integral membrane protein
HPC62_22120	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HPC62_22130	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HPC62_22160	ENOG4108IJ6	ABC transporter
HPC62_22170	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPC62_22190	ENOG410902C	phosphohistidine phosphatase, SixA
HPC62_22200	ENOG4108IJ0	Aspartate ammonia-lyase
HPC62_22220	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HPC62_22245	ENOG4108IQE	Amp-dependent synthetase and ligase
HPC62_22300	ENOG41060D5	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HPC62_22310	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HPC62_22315	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HPC62_22375	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_22415	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HPC62_22420	ENOG4105CE9	30S ribosomal protein S2
HPC62_22430	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HPC62_22450	ENOG4105K63	Thioredoxin
HPC62_22465	ENOG4105Q84	sucrose synthase
HPC62_22470	ENOG4108JJB	ABC transporter
HPC62_22475	ENOG4105VUV	UPF0367 protein
HPC62_22480	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
HPC62_22490	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_22505	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_22515	ENOG4107U45	Cobalt transport protein
HPC62_22520	ENOG41081XD	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HPC62_22535	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HPC62_22540	ENOG4105E0X	reductase
HPC62_22555	ENOG4105C7N	Xanthine uracil vitamin C permease
HPC62_22560	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
HPC62_22600	ENOG4105D38	putrescine abc transporter
HPC62_22615	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_22635	ENOG4105K64	Glycosyl transferase, family 2
HPC62_22640	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
HPC62_22645	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_22650	ENOG4105BZU	Histidine kinase
HPC62_22665	ENOG4105E2K	Glycosyl transferase (Group 1
HPC62_22695	ENOG410667J	hydrolase
HPC62_22720	ENOG4105C3G	gtp-binding protein
HPC62_22745	ENOG4107EEX	Cellulose synthase regulator protein
HPC62_22750	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HPC62_22795	ENOG4105E2X	shikimate dehydrogenase
HPC62_22800	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HPC62_22810	ENOG4105EWN	Heme oxygenase
HPC62_22825	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_22830	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HPC62_22855	ENOG4105RRH	
HPC62_22865	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HPC62_22900	ENOG4105C59	p-type ATPase
HPC62_22905	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HPC62_22910	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
HPC62_22935	ENOG4105E33	succinate dehydrogenase
HPC62_22945	ENOG4105C0H	protease