locus-tag	class	description
H9L17_00010	COG0077	Prephenate dehydratase
H9L17_00010	COG1605	Chorismate mutase
H9L17_00015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9L17_00020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9L17_00045	COG1131	(ABC) transporter
H9L17_00050	COG1725	Transcriptional regulator
H9L17_00075	COG2900	Belongs to the SlyX family
H9L17_00085	COG0646	methionine synthase
H9L17_00085	COG1410	methionine synthase
H9L17_00100	COG1960	acyl-CoA dehydrogenase activity
H9L17_00105	COG2902	Dehydrogenase
H9L17_00115	COG5001	Diguanylate cyclase
H9L17_00115	COG5002	protein histidine kinase activity
H9L17_00130	COG2925	Exonuclease
H9L17_00135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L17_00145	COG3844	kynureninase activity
H9L17_00160	COG1420	regulation of RNA biosynthetic process
H9L17_00165	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9L17_00170	COG0443	Heat shock 70 kDa protein
H9L17_00175	COG0484	heat shock protein binding
H9L17_00180	COG0287	Prephenate dehydrogenase
H9L17_00180	COG1605	Chorismate mutase
H9L17_00190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9L17_00195	COG0505	Belongs to the CarA family
H9L17_00200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9L17_00205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L17_00215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9L17_00220	COG0671	phosphoesterase, PA-phosphatase related
H9L17_00245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9L17_00255	COG2205	protein histidine kinase activity
H9L17_00255	COG0784	Response regulator, receiver
H9L17_00255	COG2198	Histidine kinase
H9L17_00260	COG1024	Enoyl-CoA hydratase
H9L17_00265	COG0318	PFAM AMP-dependent synthetase and ligase
H9L17_00280	COG3706	GGDEF domain
H9L17_00300	COG2409	Drug exporters of the RND superfamily
H9L17_00310	COG0745	RESPONSE REGULATOR receiver
H9L17_00320	COG0835	chemotaxis
H9L17_00325	COG1192	Involved in chromosome partitioning
H9L17_00330	COG1360	Flagellar Motor Protein
H9L17_00335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9L17_00340	COG2198	Histidine kinase
H9L17_00340	COG0784	Response regulator, receiver
H9L17_00340	COG0643	Histidine kinase
H9L17_00345	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H9L17_00370	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9L17_00380	COG1684	flagellar biosynthetic protein fliR
H9L17_00385	COG1987	bacterial-type flagellum assembly
H9L17_00445	COG1677	Flagellar hook-basal body complex protein FliE
H9L17_00455	COG2201	protein-glutamate methylesterase activity
H9L17_00460	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H9L17_00490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L17_00560	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H9L17_00565	COG4786	Flagellar basal body rod
H9L17_00570	COG4787	bacterial-type flagellum-dependent cell motility
H9L17_00575	COG1749	Flagellar hook protein flgE
H9L17_00580	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H9L17_00590	COG1815	bacterial-type flagellum-dependent cell motility
H9L17_00595	COG0784	Response regulator, receiver
H9L17_00595	COG0835	chemotaxis
H9L17_00620	COG5001	Diguanylate cyclase
H9L17_00620	COG3300	MHYT domain
H9L17_00695	COG0590	tRNA wobble adenosine to inosine editing
H9L17_00710	COG4974	Belongs to the 'phage' integrase family
H9L17_00725	COG1902	pentaerythritol trinitrate reductase activity
H9L17_00770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9L17_00775	COG2217	Heavy metal translocating P-type atpase
H9L17_00780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9L17_00795	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H9L17_00800	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H9L17_00825	COG0789	Transcriptional regulator
H9L17_00830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L17_00965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L17_01035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9L17_01080	COG2217	Heavy metal translocating P-type atpase
H9L17_01085	COG2608	mercury ion transmembrane transporter activity
H9L17_01090	COG2132	Multicopper oxidase
H9L17_01115	COG0714	Associated with various cellular activities
H9L17_01145	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L17_01150	COG2914	Belongs to the UPF0125 (RnfH) family
H9L17_01155	COG2867	negative regulation of translational initiation
H9L17_01160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9L17_01190	COG0668	transmembrane transport
H9L17_01195	COG2199	diguanylate cyclase activity
H9L17_01200	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H9L17_01215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9L17_01215	COG0519	Catalyzes the synthesis of GMP from XMP
H9L17_01235	COG1160	GTP binding
H9L17_01240	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L17_01260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9L17_01265	COG0105	UTP biosynthetic process
H9L17_01275	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L17_01275	COG1024	Enoyl-CoA hydratase
H9L17_01280	COG0183	Belongs to the thiolase family
H9L17_01285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9L17_01300	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H9L17_01310	COG0776	regulation of translation
H9L17_01320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9L17_01325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9L17_01335	COG2957	Belongs to the agmatine deiminase family
H9L17_01340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L17_01350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9L17_01350	COG1042	CoA-binding domain protein
H9L17_01350	COG0045	succinate-CoA ligase (ADP-forming) activity
H9L17_01375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_01400	COG3243	poly(R)-hydroxyalkanoic acid synthase
H9L17_01410	COG1183	phosphatidylcholine synthase activity
H9L17_01420	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_01430	COG1064	alcohol dehydrogenase
H9L17_01480	COG0583	DNA-binding transcription factor activity
H9L17_01485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9L17_01490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9L17_01515	COG2850	peptidyl-arginine hydroxylation
H9L17_01525	COG0567	Dehydrogenase, E1 component
H9L17_01545	COG0604	alcohol dehydrogenase
H9L17_01560	COG0678	peroxiredoxin activity
H9L17_01565	COG4953	penicillin-binding protein 1C
H9L17_01585	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H9L17_01595	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H9L17_01600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9L17_01605	COG3115	cell septum assembly
H9L17_01620	COG2350	Protein conserved in bacteria
H9L17_01630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H9L17_01635	COG1187	pseudouridine synthase activity
H9L17_01690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L17_01700	COG0436	Aminotransferase
H9L17_01740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9L17_01760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9L17_01775	COG0438	transferase activity, transferring glycosyl groups
H9L17_01780	COG0671	phosphoesterase, PA-phosphatase related
H9L17_01785	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_01805	COG0288	reversible hydration of carbon dioxide
H9L17_01825	COG4774	siderophore transport
H9L17_01830	COG2382	esterase
H9L17_01855	COG1185	polyribonucleotide nucleotidyltransferase activity
H9L17_01860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9L17_01880	COG0195	Participates in both transcription termination and antitermination
H9L17_01885	COG0779	Required for maturation of 30S ribosomal subunits
H9L17_01895	COG1007	ATP synthesis coupled electron transport
H9L17_01935	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H9L17_01940	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H9L17_01945	COG0649	NAD binding
H9L17_01950	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L17_01955	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L17_01960	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L17_01970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9L17_01970	COG0519	Catalyzes the synthesis of GMP from XMP
H9L17_01975	COG2081	HI0933 family
H9L17_01995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9L17_02005	COG0438	transferase activity, transferring glycosyl groups
H9L17_02040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H9L17_02045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H9L17_02080	COG1596	polysaccharide export
H9L17_02090	COG2895	sulfate adenylyltransferase (ATP) activity
H9L17_02090	COG0529	Catalyzes the synthesis of activated sulfate
H9L17_02095	COG0175	sulfate reduction
H9L17_02100	COG0069	glutamate synthase activity
H9L17_02120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9L17_02125	COG0322	excinuclease ABC activity
H9L17_02130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9L17_02135	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H9L17_02140	COG1663	tetraacyldisaccharide 4'-kinase activity
H9L17_02145	COG1132	(ABC) transporter
H9L17_02155	COG0811	peptide transport
H9L17_02160	COG2333	competence protein COMEC
H9L17_02160	COG0658	competence protein
H9L17_02175	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9L17_02195	COG1053	succinate dehydrogenase
H9L17_02200	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H9L17_02230	COG0028	Belongs to the TPP enzyme family
H9L17_02235	COG0022	dehydrogenase e1 component
H9L17_02240	COG0625	glutathione transferase activity
H9L17_02250	COG1960	acyl-CoA dehydrogenase activity
H9L17_02265	COG0084	hydrolase, TatD family'
H9L17_02270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9L17_02275	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
H9L17_02295	COG2133	pyrroloquinoline quinone binding
H9L17_02315	COG0386	Belongs to the glutathione peroxidase family
H9L17_02320	COG0339	signal peptide processing
H9L17_02335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9L17_02345	COG1469	GTP cyclohydrolase I activity
H9L17_02360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9L17_02365	COG0402	S-adenosylhomocysteine deaminase activity
H9L17_02375	COG1509	lysine 2,3-aminomutase activity
H9L17_02380	COG3300	MHYT domain
H9L17_02380	COG5001	Diguanylate cyclase
H9L17_02385	COG0501	Belongs to the peptidase M48B family
H9L17_02395	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_02420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9L17_02435	COG0582	viral genome integration into host DNA
H9L17_02505	COG3237	CsbD-like
H9L17_02510	COG0840	transmembrane signaling receptor activity
H9L17_02555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L17_02560	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
H9L17_02570	COG0019	diaminopimelate decarboxylase activity
H9L17_02585	COG4948	Mandelate Racemase Muconate Lactonizing
H9L17_02590	COG1737	Transcriptional regulator
H9L17_02600	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H9L17_02610	COG0460	homoserine dehydrogenase
H9L17_02610	COG0527	aspartate kinase activity
H9L17_02620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9L17_02625	COG0590	tRNA wobble adenosine to inosine editing
H9L17_02660	COG1012	belongs to the aldehyde dehydrogenase family
H9L17_02675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9L17_02690	COG2815	serine threonine protein kinase
H9L17_02690	COG0515	serine threonine protein kinase
H9L17_02700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H9L17_02705	COG1570	exodeoxyribonuclease VII activity
H9L17_02715	COG1595	DNA-templated transcription, initiation
H9L17_02725	COG1132	(ABC) transporter
H9L17_02755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H9L17_02760	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H9L17_02765	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H9L17_02770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9L17_02775	COG0617	tRNA 3'-terminal CCA addition
H9L17_02785	COG1201	RNA secondary structure unwinding
H9L17_02800	COG1187	pseudouridine synthase activity
H9L17_02810	COG0705	Rhomboid family
H9L17_02815	COG3104	oligopeptide transport
H9L17_02820	COG0625	glutathione transferase activity
H9L17_02850	COG0456	acetyltransferase
H9L17_02860	COG4774	siderophore transport
H9L17_02865	COG3128	pkhd-type hydroxylase
H9L17_02885	COG1477	protein flavinylation
H9L17_02890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9L17_02945	COG4969	Belongs to the N-Me-Phe pilin family
H9L17_02950	COG3275	phosphorelay sensor kinase activity
H9L17_02955	COG1611	Belongs to the LOG family
H9L17_02965	COG2095	MarC family integral membrane protein
H9L17_02970	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_02995	COG2835	tetraacyldisaccharide 4'-kinase activity
H9L17_03020	COG2969	positive regulation of protein catabolic process
H9L17_03025	COG0625	glutathione transferase activity
H9L17_03030	COG2857	Cytochrome c1
H9L17_03035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H9L17_03040	COG0723	plastoquinol--plastocyanin reductase activity
H9L17_03045	COG0741	lytic transglycosylase activity
H9L17_03050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9L17_03060	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H9L17_03065	COG0842	Transport permease protein
H9L17_03070	COG1131	(ABC) transporter
H9L17_03080	COG1309	transcriptional regulator
H9L17_03085	COG1702	phosphate starvation-inducible protein PhoH
H9L17_03090	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9L17_03095	COG4535	Mg2 and Co2 transporter CorC
H9L17_03115	COG1506	peptidase
H9L17_03115	COG0823	Involved in the tonB-independent uptake of proteins
H9L17_03120	COG1297	OPT oligopeptide transporter protein
H9L17_03125	COG3104	oligopeptide transport
H9L17_03150	COG0306	phosphate transporter
H9L17_03160	COG1253	flavin adenine dinucleotide binding
H9L17_03185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L17_03190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L17_03195	COG1862	Preprotein translocase
H9L17_03200	COG0343	queuine tRNA-ribosyltransferase activity
H9L17_03210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9L17_03215	COG1522	sequence-specific DNA binding
H9L17_03220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9L17_03230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L17_03235	COG0405	Gamma-glutamyltransferase
H9L17_03250	COG0742	ribosomal rna small subunit methyltransferase
H9L17_03255	COG0552	protein localization to endoplasmic reticulum
H9L17_03265	COG1194	a g-specific adenine glycosylase
H9L17_03270	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
H9L17_03290	COG4774	siderophore transport
H9L17_03380	COG0582	viral genome integration into host DNA
H9L17_03390	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9L17_03395	COG0149	triose-phosphate isomerase activity
H9L17_03415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9L17_03430	COG0133	tryptophan synthase activity
H9L17_03435	COG0135	phosphoribosylanthranilate isomerase activity
H9L17_03445	COG0101	tRNA pseudouridine synthase activity
H9L17_03455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9L17_03475	COG2890	protein-(glutamine-N5) methyltransferase activity
H9L17_03480	COG1999	signal sequence binding
H9L17_03485	COG0688	phosphatidylethanolamine metabolic process
H9L17_03490	COG3401	FG-GAP repeat protein
H9L17_03505	COG0433	COG0433 Predicted ATPase
H9L17_03515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L17_03540	COG0717	Belongs to the dCTP deaminase family
H9L17_03545	COG0489	protein tyrosine kinase activity
H9L17_03550	COG4771	TonB-dependent receptor
H9L17_03560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L17_03560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L17_03570	COG2878	Part of a membrane complex involved in electron transport
H9L17_03590	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9L17_03595	COG0802	atpase or kinase
H9L17_03600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9L17_03600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H9L17_03605	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9L17_03615	COG3654	unkown
H9L17_03630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9L17_03635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L17_03660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9L17_03665	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H9L17_03675	COG0826	peptidase U32
H9L17_03680	COG0826	peptidase U32
H9L17_03685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H9L17_03695	COG3154	lipid carrier protein
H9L17_03740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L17_03745	COG3278	Belongs to the heme-copper respiratory oxidase family
H9L17_03760	COG2010	Cytochrome c
H9L17_03820	COG3093	addiction module antidote protein HigA
H9L17_03825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9L17_03830	COG1393	Belongs to the ArsC family
H9L17_03845	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H9L17_03850	COG0024	Methionine aminopeptidase
H9L17_03885	COG4771	TonB-dependent receptor
H9L17_03890	COG0052	Belongs to the universal ribosomal protein uS2 family
H9L17_03895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9L17_03900	COG0038	chloride channel
H9L17_03910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9L17_03920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9L17_03935	COG0495	leucyl-tRNA aminoacylation
H9L17_04010	COG3118	belongs to the thioredoxin family
H9L17_04025	COG0840	transmembrane signaling receptor activity
H9L17_04025	COG0840	transmembrane signaling receptor activity
H9L17_04035	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9L17_04065	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H9L17_04080	COG2197	response regulator
H9L17_04085	COG4585	Histidine kinase
H9L17_04095	COG0850	regulation of cytokinetic process
H9L17_04100	COG2894	cell division
H9L17_04105	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H9L17_04125	COG0531	amino acid
H9L17_04130	COG2814	Major facilitator Superfamily
H9L17_04150	COG2815	serine threonine protein kinase
H9L17_04150	COG0515	serine threonine protein kinase
H9L17_04160	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9L17_04160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9L17_04165	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H9L17_04165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L17_04180	COG1725	Transcriptional regulator
H9L17_04185	COG1131	(ABC) transporter
H9L17_04210	COG0330	HflC and HflK could
H9L17_04215	COG0330	HflC and HflK could
H9L17_04220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9L17_04225	COG1923	regulation of RNA biosynthetic process
H9L17_04230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9L17_04235	COG0531	amino acid
H9L17_04240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9L17_04245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9L17_04250	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H9L17_04255	COG1534	Rna-binding protein
H9L17_04265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L17_04275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9L17_04295	COG0481	GTPase activity
H9L17_04300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9L17_04315	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L17_04315	COG1024	Enoyl-CoA hydratase
H9L17_04330	COG1506	peptidase
H9L17_04330	COG0823	Involved in the tonB-independent uptake of proteins
H9L17_04340	COG1131	(ABC) transporter
H9L17_04345	COG1725	Transcriptional regulator
H9L17_04360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9L17_04365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9L17_04375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9L17_04395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9L17_04405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L17_04410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9L17_04415	COG1399	metal-binding, possibly nucleic acid-binding protein
H9L17_04440	COG0714	Associated with various cellular activities
H9L17_04455	COG0537	adenosine 5'-monophosphoramidase activity
H9L17_04470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9L17_04515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9L17_04530	COG2723	6-phospho-beta-galactosidase activity
H9L17_04565	COG3642	lipopolysaccharide core region biosynthetic process
H9L17_04570	COG0859	PFAM glycosyl transferase family 9
H9L17_04590	COG0631	protein serine/threonine phosphatase activity
H9L17_04595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9L17_04610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L17_04645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9L17_04655	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9L17_04690	COG0473	3-isopropylmalate dehydrogenase activity
H9L17_04695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9L17_04705	COG4783	chaperone-mediated protein folding
H9L17_04720	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H9L17_04735	COG4452	Inner membrane protein CreD
H9L17_04740	COG2205	protein histidine kinase activity
H9L17_04745	COG0745	RESPONSE REGULATOR receiver
H9L17_04750	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H9L17_04755	COG2354	Protein conserved in bacteria
H9L17_04765	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9L17_04775	COG1515	deoxyribonuclease V activity
H9L17_05030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H9L17_05040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H9L17_05045	COG1137	ATPase activity
H9L17_05080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9L17_05090	COG2239	Acts as a magnesium transporter
H9L17_05100	COG0393	Putative heavy-metal-binding
H9L17_05105	COG0540	Belongs to the ATCase OTCase family
H9L17_05110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9L17_05115	COG1678	Uncharacterized ACR, COG1678
H9L17_05130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9L17_05150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9L17_05155	COG0259	pyridoxamine-phosphate oxidase activity
H9L17_05175	COG0515	serine threonine protein kinase
H9L17_05200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9L17_05215	COG3038	cytochrome b561
H9L17_05230	COG1760	l-serine dehydratase
H9L17_05235	COG3706	GGDEF domain
H9L17_05240	COG5002	protein histidine kinase activity
H9L17_05240	COG5001	Diguanylate cyclase
H9L17_05245	COG0460	homoserine dehydrogenase
H9L17_05245	COG0527	aspartate kinase activity
H9L17_05250	COG0626	cystathionine gamma-synthase activity
H9L17_05255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9L17_05260	COG0739	heme binding
H9L17_05285	COG0463	Glycosyl transferase, family 2
H9L17_05295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9L17_05340	COG0457	Tetratricopeptide repeat
H9L17_05350	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
H9L17_05355	COG1309	transcriptional regulator
H9L17_05360	COG1960	acyl-CoA dehydrogenase activity
H9L17_05420	COG0210	DNA helicase
H9L17_05425	COG0501	Belongs to the peptidase M48B family
H9L17_05430	COG1704	LemA family
H9L17_05465	COG0330	HflC and HflK could
H9L17_05510	COG2119	membrane
H9L17_05520	COG2211	Major facilitator Superfamily
H9L17_05525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L17_05535	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H9L17_05540	COG0602	queuosine metabolic process
H9L17_05550	COG2885	chlorophyll binding
H9L17_05565	COG0848	biopolymer transport protein
H9L17_05575	COG0824	Thioesterase
H9L17_05580	COG2255	four-way junction helicase activity
H9L17_05585	COG3447	MASE1 domain protein
H9L17_05585	COG5001	Diguanylate cyclase
H9L17_05585	COG5002	protein histidine kinase activity
H9L17_05595	COG0632	four-way junction helicase activity
H9L17_05605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H9L17_05610	COG0217	transcriptional regulatory protein
H9L17_05620	COG4191	Histidine kinase
H9L17_05625	COG5001	Diguanylate cyclase
H9L17_05625	COG3300	MHYT domain
H9L17_05630	COG2267	carboxylic ester hydrolase activity
H9L17_05655	COG0488	(ABC) transporter
H9L17_05660	COG4206	TonB-dependent receptor
H9L17_05665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9L17_05665	COG4651	solute:proton antiporter activity
H9L17_05670	COG5002	protein histidine kinase activity
H9L17_05670	COG5001	Diguanylate cyclase
H9L17_05675	COG0542	response to heat
H9L17_05685	COG2885	chlorophyll binding
H9L17_05720	COG3011	Protein conserved in bacteria
H9L17_05735	COG0564	pseudouridine synthase activity
H9L17_05740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L17_05760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H9L17_05775	COG2207	Transcriptional regulator
H9L17_05775	COG1917	Cupin 2, conserved barrel domain protein
H9L17_05800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9L17_05805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9L17_05815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9L17_05820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9L17_05825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9L17_05835	COG0356	it plays a direct role in the translocation of protons across the membrane
H9L17_05850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L17_05855	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L17_05865	COG1666	GTP binding
H9L17_05880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9L17_05885	COG1187	pseudouridine synthase activity
H9L17_05920	COG4941	Belongs to the sigma-70 factor family
H9L17_05930	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H9L17_05935	COG3795	YCII-related domain
H9L17_05940	COG3795	YCII-related domain
H9L17_05945	COG1793	dna ligase
H9L17_05955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L17_05965	COG2814	Major facilitator Superfamily
H9L17_05970	COG2972	Histidine kinase
H9L17_06000	COG2818	Glycosylase
H9L17_06015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L17_06030	COG3588	fructose-bisphosphate aldolase
H9L17_06035	COG1560	Kdo2-lipid A biosynthetic process
H9L17_06040	COG0469	pyruvate kinase activity
H9L17_06045	COG0126	phosphoglycerate kinase activity
H9L17_06075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9L17_06095	COG3682	Transcriptional regulator
H9L17_06115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H9L17_06170	COG0714	Associated with various cellular activities
H9L17_06215	COG0254	rRNA binding
H9L17_06260	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9L17_06265	COG0640	Transcriptional regulator
H9L17_06275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9L17_06305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9L17_06315	COG0194	GDP metabolic process
H9L17_06320	COG1561	YicC-like family, N-terminal region
H9L17_06325	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H9L17_06335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9L17_06350	COG0006	proline dipeptidase activity
H9L17_06360	COG0006	proline dipeptidase activity
H9L17_06365	COG3079	Belongs to the UPF0149 family
H9L17_06390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9L17_06405	COG0129	dihydroxy-acid dehydratase activity
H9L17_06410	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9L17_06435	COG0473	3-isopropylmalate dehydrogenase activity
H9L17_06445	COG0066	3-isopropylmalate dehydratase activity
H9L17_06450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H9L17_06460	COG5001	Diguanylate cyclase
H9L17_06460	COG3300	MHYT domain
H9L17_06470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_06475	COG1309	transcriptional regulator
H9L17_06480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9L17_06485	COG1538	Outer membrane efflux protein
H9L17_06490	COG1519	Transferase
H9L17_06495	COG1560	Kdo2-lipid A biosynthetic process
H9L17_06505	COG0297	glycogen (starch) synthase activity
H9L17_06515	COG1741	Belongs to the pirin family
H9L17_06520	COG2353	YceI-like domain
H9L17_06525	COG0778	Nitroreductase
H9L17_06535	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H9L17_06540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9L17_06570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9L17_06575	COG1324	tolerance protein
H9L17_06580	COG4232	protein-disulfide reductase activity
H9L17_06585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9L17_06590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9L17_06595	COG0511	ligase activity, forming carbon-carbon bonds
H9L17_06600	COG0439	Biotin carboxylase
H9L17_06610	COG2264	protein methyltransferase activity
H9L17_06620	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H9L17_06625	COG0138	bifunctional purine biosynthesis protein purh
H9L17_06630	COG0456	acetyltransferase
H9L17_06630	COG0454	-acetyltransferase
H9L17_06635	COG0151	Belongs to the GarS family
H9L17_06645	COG4181	ATPase activity
H9L17_06660	COG3384	dioxygenase
H9L17_06730	COG2906	2 iron, 2 sulfur cluster binding
H9L17_06735	COG0720	synthase
H9L17_06750	COG1183	phosphatidylcholine synthase activity
H9L17_06765	COG0442	prolyl-tRNA aminoacylation
H9L17_06780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9L17_06785	COG1127	ABC transporter
H9L17_06815	COG2086	electron transfer activity
H9L17_06830	COG1215	transferase activity, transferring glycosyl groups
H9L17_06850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9L17_06905	COG1459	type II secretion system
H9L17_06910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9L17_06960	COG1450	Type ii and iii secretion system protein
H9L17_06970	COG0617	tRNA 3'-terminal CCA addition
H9L17_06970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9L17_06970	COG3620	sequence-specific DNA binding
H9L17_06980	COG2885	chlorophyll binding
H9L17_06990	COG0625	glutathione transferase activity
H9L17_07010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9L17_07015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9L17_07020	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
H9L17_07035	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H9L17_07040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L17_07060	COG0134	indole-3-glycerol-phosphate synthase activity
H9L17_07070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9L17_07080	COG0642	Histidine kinase
H9L17_07085	COG0745	RESPONSE REGULATOR receiver
H9L17_07135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H9L17_07140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9L17_07150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H9L17_07165	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H9L17_07190	COG0673	inositol 2-dehydrogenase activity
H9L17_07200	COG1501	Belongs to the glycosyl hydrolase 31 family
H9L17_07205	COG2222	sugar isomerase
H9L17_07210	COG1940	carbohydrate kinase activity
H9L17_07220	COG1349	DNA-binding transcription factor activity
H9L17_07225	COG3104	oligopeptide transport
H9L17_07230	COG3483	tryptophan 2,3-dioxygenase activity
H9L17_07270	COG1846	Transcriptional regulator
H9L17_07280	COG0180	Tryptophanyl-tRNA synthetase
H9L17_07300	COG2323	membrane
H9L17_07310	COG1132	(ABC) transporter
H9L17_07320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L17_07325	COG0210	DNA helicase
H9L17_07350	COG1609	Transcriptional regulator
H9L17_07355	COG1472	Belongs to the glycosyl hydrolase 3 family
H9L17_07365	COG0625	glutathione transferase activity
H9L17_07370	COG0662	Cupin 2, conserved barrel domain protein
H9L17_07375	COG1506	peptidase
H9L17_07375	COG0823	Involved in the tonB-independent uptake of proteins
H9L17_07410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9L17_07445	COG0357	Ribosomal RNA small subunit methyltransferase G
H9L17_07450	COG1192	Involved in chromosome partitioning
H9L17_07460	COG0463	Glycosyl transferase, family 2
H9L17_07485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9L17_07495	COG1968	undecaprenyl-diphosphatase activity
H9L17_07500	COG0174	glutamine synthetase
H9L17_07510	COG0347	Belongs to the P(II) protein family
H9L17_07515	COG0004	ammonium transporteR
H9L17_07525	COG3023	N-Acetylmuramoyl-L-alanine amidase
H9L17_07530	COG4206	TonB-dependent receptor
H9L17_07535	COG4774	siderophore transport
H9L17_07585	COG3291	Pkd domain containing protein
H9L17_07595	COG0006	proline dipeptidase activity
H9L17_07610	COG3938	Belongs to the proline racemase family
H9L17_07615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9L17_07660	COG1051	belongs to the nudix hydrolase family
H9L17_07660	COG1056	cytidyltransferase-related domain
H9L17_07675	COG3852	Histidine kinase
H9L17_07680	COG2204	response regulator
H9L17_07685	COG2032	superoxide dismutase activity
H9L17_07710	COG0515	serine threonine protein kinase
H9L17_07740	COG0183	Belongs to the thiolase family
H9L17_07775	COG1271	oxidase subunit
H9L17_07785	COG1294	oxidase, subunit
H9L17_07790	COG3100	YcgL domain-containing protein
H9L17_07800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9L17_07800	COG0475	glutathione-regulated potassium exporter activity
H9L17_07815	COG0493	'glutamate synthase
H9L17_07820	COG0070	glutamate synthase
H9L17_07820	COG0069	glutamate synthase activity
H9L17_07820	COG0067	glutamate synthase
H9L17_07845	COG2922	Belongs to the Smg family
H9L17_07850	COG0758	DNA mediated transformation
H9L17_07860	COG0242	peptide deformylase activity
H9L17_07870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9L17_07870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9L17_07875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H9L17_07880	COG0438	transferase activity, transferring glycosyl groups
H9L17_07885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9L17_07900	COG0210	DNA helicase
H9L17_07915	COG3300	MHYT domain
H9L17_07915	COG5001	Diguanylate cyclase
H9L17_07920	COG2937	Belongs to the GPAT DAPAT family
H9L17_07925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9L17_07935	COG0037	tRNA processing
H9L17_07940	COG2974	May be involved in recombination
H9L17_07955	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9L17_07970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9L17_07990	COG0519	Catalyzes the synthesis of GMP from XMP
H9L17_07990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9L17_08000	COG0625	glutathione transferase activity
H9L17_08010	COG0729	surface antigen
H9L17_08030	COG0445	tRNA wobble uridine modification
H9L17_08035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9L17_08040	COG5002	protein histidine kinase activity
H9L17_08050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9L17_08055	COG3437	response regulator, receiver
H9L17_08055	COG4999	Histidine kinase
H9L17_08055	COG3850	Histidine kinase
H9L17_08055	COG2205	protein histidine kinase activity
H9L17_08065	COG2267	carboxylic ester hydrolase activity
H9L17_08075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9L17_08080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L17_08090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L17_08095	COG4771	TonB-dependent receptor
H9L17_08100	COG0457	Tetratricopeptide repeat
H9L17_08115	COG0156	8-amino-7-oxononanoate synthase activity
H9L17_08120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9L17_08125	COG1040	competence protein
H9L17_08175	COG2945	thiolester hydrolase activity
H9L17_08180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H9L17_08185	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9L17_08185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9L17_08190	COG1652	LysM domain
H9L17_08210	COG1187	pseudouridine synthase activity
H9L17_08225	COG1643	Atp-dependent helicase
H9L17_08230	COG0084	hydrolase, TatD family'
H9L17_08245	COG0842	Transport permease protein
H9L17_08250	COG1131	(ABC) transporter
H9L17_08300	COG4964	Belongs to the GSP D family
H9L17_08360	COG2267	carboxylic ester hydrolase activity
H9L17_08365	COG4555	ABC transporter
H9L17_08385	COG0706	membrane insertase activity
H9L17_08410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9L17_08415	COG0187	DNA topoisomerase II activity
H9L17_08460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L17_08475	COG1741	Belongs to the pirin family
H9L17_08480	COG3273	potassium ion transport
H9L17_08480	COG0471	metal ion transport
H9L17_08485	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H9L17_08495	COG5487	UPF0391 membrane protein
H9L17_08500	COG3186	Phenylalanine-4-hydroxylase
H9L17_08510	COG1595	DNA-templated transcription, initiation
H9L17_08525	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9L17_08530	COG3647	Membrane
H9L17_08545	COG0861	Integral membrane protein TerC family
H9L17_08550	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9L17_08565	COG2853	Lipoprotein
H9L17_08575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9L17_08580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9L17_08585	COG1127	ABC transporter
H9L17_08590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H9L17_08595	COG1074	ATP-dependent DNA helicase activity
H9L17_08615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L17_08620	COG2226	methyltransferase
H9L17_08625	COG0534	Mate efflux family protein
H9L17_08635	COG0346	lactoylglutathione lyase activity
H9L17_08640	COG3122	Protein conserved in bacteria
H9L17_08645	COG1451	nucleotide metabolic process
H9L17_08660	COG1960	acyl-CoA dehydrogenase activity
H9L17_08670	COG3408	Glycogen debranching enzyme
H9L17_08670	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
H9L17_08685	COG0302	gtp cyclohydrolase
H9L17_08720	COG3550	peptidyl-serine autophosphorylation
H9L17_08730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9L17_08740	COG2188	Transcriptional regulator
H9L17_08745	COG1609	Transcriptional regulator
H9L17_08750	COG0738	Major facilitator superfamily
H9L17_08755	COG0837	glucose binding
H9L17_08765	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9L17_08780	COG2062	phosphohistidine phosphatase, SixA
H9L17_08785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L17_08795	COG2050	protein possibly involved in aromatic compounds catabolism
H9L17_08810	COG1881	PFAM PEBP family protein
H9L17_08845	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9L17_08890	COG1505	serine-type exopeptidase activity
H9L17_08915	COG0612	Peptidase, M16
H9L17_08925	COG2932	Transcriptional regulator
H9L17_08935	COG2378	regulation of single-species biofilm formation
H9L17_08960	COG0181	hydroxymethylbilane synthase activity
H9L17_08980	COG1368	sulfuric ester hydrolase activity
H9L17_08985	COG0745	RESPONSE REGULATOR receiver
H9L17_08990	COG2205	protein histidine kinase activity
H9L17_09000	COG3537	Alpha-1,2-mannosidase
H9L17_09005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9L17_09010	COG1490	D-aminoacyl-tRNA deacylase activity
H9L17_09025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H9L17_09035	COG0515	serine threonine protein kinase
H9L17_09040	COG3590	peptidase
H9L17_09045	COG0477	Major facilitator Superfamily
H9L17_09080	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_09090	COG0616	signal peptide processing
H9L17_09095	COG0534	Mate efflux family protein
H9L17_09115	COG4585	Histidine kinase
H9L17_09130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9L17_09140	COG3250	beta-galactosidase activity
H9L17_09150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L17_09160	COG1609	Transcriptional regulator
H9L17_09165	COG3537	Alpha-1,2-mannosidase
H9L17_09180	COG1252	NADH dehydrogenase
H9L17_09185	COG2860	membrane
H9L17_09200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9L17_09205	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H9L17_09220	COG2022	thiamine diphosphate biosynthetic process
H9L17_09235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9L17_09260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9L17_09265	COG3118	belongs to the thioredoxin family
H9L17_09275	COG2884	Cell division ATP-binding protein ftsE
H9L17_09280	COG2177	Part of the ABC transporter FtsEX involved in
H9L17_09285	COG2201	protein-glutamate methylesterase activity
H9L17_09295	COG0308	aminopeptidase N
H9L17_09300	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L17_09300	COG0596	Alpha beta hydrolase
H9L17_09325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L17_09330	COG1077	Cell shape determining protein MreB Mrl
H9L17_09340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H9L17_09345	COG0768	penicillin binding
H9L17_09350	COG0772	Belongs to the SEDS family
H9L17_09355	COG2951	lytic endotransglycosylase activity
H9L17_09365	COG1686	Belongs to the peptidase S11 family
H9L17_09370	COG2921	Belongs to the UPF0250 family
H9L17_09375	COG0321	lipoyl(octanoyl) transferase activity
H9L17_09385	COG0697	spore germination
H9L17_09400	COG0577	efflux transmembrane transporter activity
H9L17_09405	COG0577	efflux transmembrane transporter activity
H9L17_09410	COG1136	(ABC) transporter
H9L17_09415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_09420	COG1131	(ABC) transporter
H9L17_09430	COG4585	Histidine kinase
H9L17_09435	COG2197	response regulator
H9L17_09450	COG0753	catalase activity
H9L17_09465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9L17_09475	COG0628	permease
H9L17_09495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9L17_09570	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H9L17_09625	COG2234	aminopeptidase activity
H9L17_09645	COG2824	Alkylphosphonate utilization operon protein PhnA
H9L17_09660	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_09675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9L17_09700	COG3228	Belongs to the MtfA family
H9L17_09715	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9L17_09730	COG0010	Belongs to the arginase family
H9L17_09740	COG0408	coproporphyrinogen oxidase activity
H9L17_09745	COG0697	spore germination
H9L17_09775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L17_09780	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H9L17_09785	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9L17_09795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H9L17_09805	COG0612	Peptidase, M16
H9L17_09815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L17_09820	COG1573	uracil-dna glycosylase
H9L17_09830	COG0596	Alpha beta hydrolase
H9L17_09850	COG2852	Protein conserved in bacteria
H9L17_09855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L17_09875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L17_09910	COG0564	pseudouridine synthase activity
H9L17_09935	COG1216	Glycosyl transferase, family 2
H9L17_09975	COG0583	DNA-binding transcription factor activity
H9L17_09980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H9L17_09985	COG2224	Isocitrate lyase
H9L17_10010	COG0606	chelatase, subunit chli
H9L17_10015	COG2960	long-chain fatty acid transporting porin activity
H9L17_10020	COG0347	Belongs to the P(II) protein family
H9L17_10030	COG1166	arginine decarboxylase activity
H9L17_10055	COG3275	phosphorelay sensor kinase activity
H9L17_10060	COG3279	Response regulator of the LytR AlgR family
H9L17_10065	COG2755	lipolytic protein G-D-S-L family
H9L17_10065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H9L17_10085	COG3596	GTP binding
H9L17_10090	COG4735	regulation of single-species biofilm formation
H9L17_10115	COG5001	Diguanylate cyclase
H9L17_10120	COG5002	protein histidine kinase activity
H9L17_10120	COG5001	Diguanylate cyclase
H9L17_10120	COG3447	MASE1 domain protein
H9L17_10125	COG4221	oxidoreductase activity
H9L17_10150	COG0018	arginyl-trna synthetase
H9L17_10160	COG2003	Belongs to the UPF0758 family
H9L17_10175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9L17_10185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9L17_10200	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H9L17_10205	COG0739	heme binding
H9L17_10210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9L17_10245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H9L17_10260	COG0577	efflux transmembrane transporter activity
H9L17_10265	COG0577	efflux transmembrane transporter activity
H9L17_10265	COG1136	(ABC) transporter
H9L17_10265	COG0577	efflux transmembrane transporter activity
H9L17_10265	COG1136	(ABC) transporter
H9L17_10270	COG0577	efflux transmembrane transporter activity
H9L17_10280	COG0577	efflux transmembrane transporter activity
H9L17_10285	COG0577	efflux transmembrane transporter activity
H9L17_10285	COG1136	(ABC) transporter
H9L17_10290	COG1136	(ABC) transporter
H9L17_10290	COG0577	efflux transmembrane transporter activity
H9L17_10305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9L17_10325	COG3781	membrane
H9L17_10335	COG0243	molybdopterin cofactor binding
H9L17_10350	COG2823	Periplasmic or secreted lipoprotein
H9L17_10365	COG1956	GAF domain-containing protein
H9L17_10375	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H9L17_10380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L17_10385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_10420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9L17_10440	COG4974	Belongs to the 'phage' integrase family
H9L17_10445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9L17_10450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9L17_10450	COG0047	phosphoribosylformylglycinamidine synthase activity
H9L17_10455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9L17_10460	COG1459	type II secretion system
H9L17_10465	COG2165	general secretion pathway protein
H9L17_10475	COG2165	general secretion pathway protein
H9L17_10480	COG4795	General secretion pathway protein
H9L17_10485	COG3156	type II secretion system protein K
H9L17_10490	COG3166	PFAM Fimbrial assembly family protein
H9L17_10505	COG1450	Type ii and iii secretion system protein
H9L17_10520	COG0284	orotidine-5'-phosphate decarboxylase activity
H9L17_10545	COG0488	(ABC) transporter
H9L17_10565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9L17_10595	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H9L17_10600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9L17_10615	COG0277	FAD linked oxidase domain protein
H9L17_10620	COG0792	nuclease activity
H9L17_10665	COG2001	Belongs to the MraZ family
H9L17_10670	COG0275	rRNA processing
H9L17_10675	COG3116	cell division
H9L17_10690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9L17_10695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9L17_10710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9L17_10715	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9L17_10720	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H9L17_10745	COG0739	heme binding
H9L17_10750	COG0653	protein targeting
H9L17_10755	COG0494	nUDIX hydrolase
H9L17_10765	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H9L17_10780	COG0463	Glycosyl transferase, family 2
H9L17_10785	COG0438	transferase activity, transferring glycosyl groups
H9L17_10790	COG1215	transferase activity, transferring glycosyl groups
H9L17_10795	COG1442	glycosyl transferase family 8
H9L17_10830	COG2755	lipolytic protein G-D-S-L family
H9L17_10830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H9L17_10865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9L17_10870	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H9L17_10880	COG1872	DUF167
H9L17_10905	COG0563	adenylate kinase activity
H9L17_10910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9L17_10915	COG0671	phosphoesterase, PA-phosphatase related
H9L17_10920	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_10925	COG0346	lactoylglutathione lyase activity
H9L17_10930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9L17_10935	COG4771	TonB-dependent receptor
H9L17_10945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L17_10950	COG1940	carbohydrate kinase activity
H9L17_10950	COG1846	Transcriptional regulator
H9L17_10970	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9L17_10975	COG1773	rubredoxin
H9L17_11015	COG2234	aminopeptidase activity
H9L17_11025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9L17_11030	COG4942	peptidase
H9L17_11035	COG0793	Belongs to the peptidase S41A family
H9L17_11055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9L17_11060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9L17_11070	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H9L17_11100	COG0109	protoheme IX farnesyltransferase activity
H9L17_11105	COG3145	DNA-N1-methyladenine dioxygenase activity
H9L17_11110	COG2169	Transcriptional regulator
H9L17_11110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9L17_11115	COG0038	chloride channel
H9L17_11130	COG0358	DNA primase activity
H9L17_11135	COG1295	ribonuclease BN
H9L17_11155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9L17_11160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9L17_11165	COG0300	oxidoreductase activity
H9L17_11190	COG0617	tRNA 3'-terminal CCA addition
H9L17_11200	COG0730	response to heat
H9L17_11220	COG2863	cytochrome
H9L17_11235	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H9L17_11240	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H9L17_11265	COG1307	EDD domain protein, DegV family
H9L17_11275	COG1228	amidohydrolase
H9L17_11295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H9L17_11315	COG3038	cytochrome b561
H9L17_11325	COG0436	Aminotransferase
H9L17_11330	COG1162	GTPase activity
H9L17_11340	COG0281	malic enzyme
H9L17_11340	COG0280	phosphate acetyltransferase
H9L17_11350	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H9L17_11360	COG1970	mechanosensitive ion channel activity
H9L17_11385	COG0471	metal ion transport
H9L17_11385	COG3273	potassium ion transport
H9L17_11410	COG0745	RESPONSE REGULATOR receiver
H9L17_11415	COG0642	Histidine kinase
H9L17_11420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9L17_11430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9L17_11445	COG3275	phosphorelay sensor kinase activity
H9L17_11450	COG3279	Response regulator of the LytR AlgR family
H9L17_11455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H9L17_11460	COG0488	(ABC) transporter
H9L17_11485	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L17_11495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9L17_11515	COG0514	ATP-dependent DNA helicase (RecQ)
H9L17_11520	COG0783	Belongs to the Dps family
H9L17_11525	COG1643	Atp-dependent helicase
H9L17_11530	COG1643	Atp-dependent helicase
H9L17_11535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9L17_11545	COG0438	transferase activity, transferring glycosyl groups
H9L17_11545	COG1216	Glycosyl transferase, family 2
H9L17_11550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9L17_11555	COG1199	ATP-dependent helicase activity
H9L17_11580	COG0189	ligase activity
H9L17_11600	COG0840	transmembrane signaling receptor activity
H9L17_11605	COG0643	Histidine kinase
H9L17_11605	COG0784	Response regulator, receiver
H9L17_11605	COG2198	Histidine kinase
H9L17_11610	COG2201	protein-glutamate methylesterase activity
H9L17_11625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9L17_11635	COG0494	nUDIX hydrolase
H9L17_11640	COG1218	3'(2'),5'-bisphosphate nucleotidase
H9L17_11645	COG3956	TIGRFAM MazG family protein
H9L17_11665	COG0642	Histidine kinase
H9L17_11670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_11675	COG1136	(ABC) transporter
H9L17_11675	COG0577	efflux transmembrane transporter activity
H9L17_11680	COG0577	efflux transmembrane transporter activity
H9L17_11680	COG1136	(ABC) transporter
H9L17_11685	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9L17_11690	COG0861	Integral membrane protein TerC family
H9L17_11695	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9L17_11710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9L17_11715	COG2967	ApaG domain
H9L17_11725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L17_11730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H9L17_11735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L17_11740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H9L17_11745	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9L17_11750	COG2096	Adenosyltransferase
H9L17_11760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L17_11765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L17_11785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9L17_11805	COG0583	DNA-binding transcription factor activity
H9L17_11845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L17_11845	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L17_11885	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H9L17_11895	COG2151	metal-sulfur cluster biosynthetic enzyme
H9L17_11900	COG3227	Zinc metalloprotease (Elastase)
H9L17_11910	COG0457	Tetratricopeptide repeat
H9L17_11925	COG1295	ribonuclease BN
H9L17_11930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9L17_11935	COG1254	Belongs to the acylphosphatase family
H9L17_11950	COG0456	acetyltransferase
H9L17_11955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9L17_11960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9L17_11975	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9L17_11985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9L17_11995	COG0193	aminoacyl-tRNA hydrolase activity
H9L17_12000	COG0012	GTP binding
H9L17_12020	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9L17_12030	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9L17_12035	COG0250	Participates in transcription elongation, termination and antitermination
H9L17_12040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9L17_12050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9L17_12055	COG0222	ribosome binding
H9L17_12065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9L17_12070	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9L17_12075	COG0049	tRNA binding
H9L17_12080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9L17_12085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9L17_12090	COG0051	transcription antitermination factor activity, RNA binding
H9L17_12095	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9L17_12100	COG0088	Forms part of the polypeptide exit tunnel
H9L17_12105	COG0089	rRNA binding
H9L17_12110	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9L17_12120	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9L17_12125	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9L17_12130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9L17_12140	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9L17_12150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9L17_12155	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9L17_12170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9L17_12175	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9L17_12180	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9L17_12185	COG1841	ribosomal large subunit assembly
H9L17_12190	COG0200	Binds to the 23S rRNA
H9L17_12195	COG0201	protein transport
H9L17_12200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9L17_12205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9L17_12210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9L17_12220	COG0203	ribosomal protein L17
H9L17_12230	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
H9L17_12240	COG0154	amidase activity
H9L17_12250	COG1217	gtp-binding protein TYPA
H9L17_12255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9L17_12270	COG0039	L-malate dehydrogenase activity
H9L17_12275	COG3706	GGDEF domain
H9L17_12290	COG0625	glutathione transferase activity
H9L17_12300	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9L17_12300	COG1902	pentaerythritol trinitrate reductase activity
H9L17_12315	COG1187	pseudouridine synthase activity
H9L17_12320	COG0156	8-amino-7-oxononanoate synthase activity
H9L17_12330	COG1063	alcohol dehydrogenase
H9L17_12345	COG0406	alpha-ribazole phosphatase activity
H9L17_12350	COG4989	oxidoreductase activity
H9L17_12355	COG0285	dihydrofolate synthase activity
H9L17_12370	COG2833	Protein of unknown function (DUF455)
H9L17_12385	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L17_12390	COG0515	serine threonine protein kinase
H9L17_12420	COG0735	belongs to the Fur family
H9L17_12445	COG1228	amidohydrolase
H9L17_12450	COG0010	Belongs to the arginase family
H9L17_12455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9L17_12465	COG1309	transcriptional regulator
H9L17_12485	COG0488	(ABC) transporter
H9L17_12500	COG2837	iron assimilation
H9L17_12520	COG1073	alpha beta
H9L17_12525	COG1506	peptidase
H9L17_12525	COG0823	Involved in the tonB-independent uptake of proteins
H9L17_12540	COG0513	Belongs to the DEAD box helicase family
H9L17_12555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H9L17_12580	COG3267	Type II secretory pathway component ExeA
H9L17_12580	COG3409	Peptidoglycan-binding domain 1 protein
H9L17_12595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L17_12610	COG0384	phenazine biosynthesis protein PhzF
H9L17_12615	COG0527	aspartate kinase activity
H9L17_12625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9L17_12635	COG0142	geranyltranstransferase activity
H9L17_12640	COG0629	single-stranded DNA binding
H9L17_12650	COG0791	NLP P60 protein
H9L17_12655	COG0791	NLP P60 protein
H9L17_12665	COG2311	Membrane
H9L17_12670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L17_12690	COG1446	asparaginase
H9L17_12695	COG3142	Participates in the control of copper homeostasis
H9L17_12705	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H9L17_12710	COG0148	phosphopyruvate hydratase activity
H9L17_12715	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H9L17_12725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9L17_12755	COG1238	metal cluster binding
H9L17_12775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9L17_12790	COG0628	permease
H9L17_12800	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H9L17_12805	COG3178	'Phosphotransferase
H9L17_12830	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_12865	COG1648	precorrin-2 dehydrogenase activity
H9L17_12865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9L17_12870	COG0583	DNA-binding transcription factor activity
H9L17_12880	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9L17_12890	COG1959	2 iron, 2 sulfur cluster binding
H9L17_12905	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H9L17_12915	COG4208	sulfate ABC transporter
H9L17_12920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H9L17_12960	COG0424	maF-like protein
H9L17_12975	COG0312	modulator of DNA gyrase
H9L17_12985	COG0312	modulator of DNA gyrase
H9L17_13000	COG0142	geranyltranstransferase activity
H9L17_13005	COG1722	exodeoxyribonuclease VII activity
H9L17_13010	COG0037	tRNA processing
H9L17_13015	COG0825	malonyl-CoA metabolic process
H9L17_13030	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L17_13035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L17_13040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9L17_13055	COG0750	zinc metalloprotease
H9L17_13060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9L17_13065	COG0575	Belongs to the CDS family
H9L17_13070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9L17_13085	COG3706	GGDEF domain
H9L17_13095	COG4970	Tfp pilus assembly protein FimT
H9L17_13110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9L17_13115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H9L17_13130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9L17_13200	COG1073	alpha beta
H9L17_13230	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H9L17_13250	COG1946	Acyl-CoA thioesterase
H9L17_13270	COG0116	Belongs to the methyltransferase superfamily
H9L17_13270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9L17_13275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9L17_13285	COG1177	transmembrane transport
H9L17_13290	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9L17_13295	COG3842	ATPase activity
H9L17_13300	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H9L17_13315	COG1960	acyl-CoA dehydrogenase activity
H9L17_13330	COG3590	peptidase
H9L17_13335	COG3590	peptidase
H9L17_13345	COG0612	Peptidase, M16
H9L17_13365	COG3275	phosphorelay sensor kinase activity
H9L17_13375	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H9L17_13395	COG0513	Belongs to the DEAD box helicase family
H9L17_13400	COG2194	sulfuric ester hydrolase activity
H9L17_13405	COG0840	transmembrane signaling receptor activity
H9L17_13420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9L17_13425	COG0719	Fe-S assembly protein
H9L17_13430	COG0396	ATPase activity
H9L17_13435	COG0719	Fe-S assembly protein
H9L17_13440	COG1959	2 iron, 2 sulfur cluster binding
H9L17_13510	COG0457	Tetratricopeptide repeat
H9L17_13515	COG4771	TonB-dependent receptor
H9L17_13525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9L17_13545	COG1981	membrane
H9L17_13550	COG1785	Belongs to the alkaline phosphatase family
H9L17_13555	COG1301	dicarboxylic acid transport
H9L17_13575	COG3387	PFAM Glycoside hydrolase 15-related
H9L17_13580	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H9L17_13625	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9L17_13675	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_13720	COG0557	exoribonuclease II activity
H9L17_13730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9L17_13745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9L17_13765	COG0704	Plays a role in the regulation of phosphate uptake
H9L17_13780	COG0573	inorganic phosphate transmembrane transporter activity
H9L17_13800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9L17_13810	COG1024	Enoyl-CoA hydratase
H9L17_13830	COG1393	Belongs to the ArsC family
H9L17_13850	COG0824	Thioesterase
H9L17_13855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9L17_13860	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9L17_13865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9L17_13870	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9L17_13875	COG0268	Binds directly to 16S ribosomal RNA
H9L17_13880	COG0728	peptidoglycan biosynthetic process
H9L17_13885	COG0196	riboflavin kinase activity
H9L17_13900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9L17_13920	COG2814	Major facilitator Superfamily
H9L17_13925	COG1566	PFAM secretion protein HlyD family protein
H9L17_13940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9L17_13960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9L17_13965	COG0315	cyclic pyranopterin monophosphate synthase activity
H9L17_13965	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9L17_13970	COG0303	'Molybdopterin
H9L17_13980	COG0314	molybdopterin synthase activity
H9L17_13985	COG0746	molybdenum cofactor guanylyltransferase activity
H9L17_14000	COG2223	nitrite transmembrane transporter activity
H9L17_14005	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H9L17_14010	COG1140	nitrate reductase beta subunit
H9L17_14015	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H9L17_14020	COG2181	nitrate reductase activity
H9L17_14025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L17_14035	COG4771	TonB-dependent receptor
H9L17_14045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9L17_14070	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H9L17_14075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9L17_14080	COG4772	TonB-dependent receptor
H9L17_14095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H9L17_14110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9L17_14120	COG5002	protein histidine kinase activity
H9L17_14120	COG3447	MASE1 domain protein
H9L17_14120	COG5001	Diguanylate cyclase
H9L17_14125	COG0228	four-way junction DNA binding
H9L17_14130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9L17_14135	COG0336	Belongs to the RNA methyltransferase TrmD family
H9L17_14160	COG1522	sequence-specific DNA binding
H9L17_14165	COG0626	cystathionine gamma-synthase activity
H9L17_14180	COG0753	catalase activity
H9L17_14185	COG2258	MOSC domain
H9L17_14200	COG1546	Belongs to the CinA family
H9L17_14210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9L17_14215	COG2137	regulation of response to DNA damage stimulus
H9L17_14230	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H9L17_14310	COG4791	protein targeting
H9L17_14320	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9L17_14325	COG4786	Flagellar basal body rod
H9L17_14330	COG4786	Flagellar basal body rod
H9L17_14345	COG1706	bacterial-type flagellum-dependent cell motility
H9L17_14360	COG1677	Flagellar hook-basal body complex protein FliE
H9L17_14380	COG1157	protein secretion by the type III secretion system
H9L17_14395	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H9L17_14430	COG1191	sigma factor activity
H9L17_14460	COG0366	Alpha amylase catalytic
H9L17_14465	COG1082	Xylose isomerase domain protein TIM barrel
H9L17_14480	COG1695	Transcriptional regulator
H9L17_14500	COG3620	sequence-specific DNA binding
H9L17_14505	COG1073	alpha beta
H9L17_14510	COG0800	Aldolase
H9L17_14530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9L17_14550	COG0659	secondary active sulfate transmembrane transporter activity
H9L17_14565	COG2944	sequence-specific DNA binding
H9L17_14575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9L17_14580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9L17_14590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9L17_14600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H9L17_14610	COG2166	iron-sulfur cluster assembly
H9L17_14625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9L17_14630	COG0137	argininosuccinate synthase activity
H9L17_14635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9L17_14640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9L17_14645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9L17_14650	COG0165	Argininosuccinate lyase
H9L17_14660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9L17_14675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9L17_14685	COG0124	histidyl-tRNA synthetase
H9L17_14690	COG2986	histidine ammonia-lyase
H9L17_14700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H9L17_14705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9L17_14710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9L17_14720	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H9L17_14725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9L17_14735	COG0140	phosphoribosyl-ATP diphosphatase activity
H9L17_14735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9L17_14740	COG5001	Diguanylate cyclase
H9L17_14740	COG2203	Gaf domain
H9L17_14740	COG3706	GGDEF domain
H9L17_14740	COG4251	negative regulation of phosphorylation
H9L17_14755	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
H9L17_14760	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H9L17_14765	COG0235	Class ii aldolase
H9L17_14770	COG0235	Class ii aldolase
H9L17_14775	COG0531	amino acid
H9L17_14780	COG0531	amino acid
H9L17_14790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9L17_14795	COG0277	FAD linked oxidase domain protein
H9L17_14815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9L17_14855	COG1024	Enoyl-CoA hydratase
H9L17_14855	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L17_14865	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9L17_14865	COG1918	ferrous iron import across plasma membrane
H9L17_14900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9L17_14905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9L17_14910	COG2954	triphosphatase activity
H9L17_14915	COG1472	Belongs to the glycosyl hydrolase 3 family
H9L17_14920	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H9L17_14925	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H9L17_14930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L17_14935	COG1278	Cold shock
H9L17_14950	COG0183	Belongs to the thiolase family
H9L17_14955	COG1404	Belongs to the peptidase S8 family
H9L17_14960	COG2915	High frequency lysogenization protein hflD homolog
H9L17_14965	COG0482	sulfurtransferase activity
H9L17_14980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H9L17_14985	COG0542	response to heat
H9L17_15005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9L17_15035	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9L17_15045	COG1024	Enoyl-CoA hydratase
H9L17_15050	COG1024	Enoyl-CoA hydratase
H9L17_15055	COG1960	acyl-CoA dehydrogenase activity
H9L17_15080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9L17_15110	COG2183	response to ionizing radiation
H9L17_15120	COG0477	Major facilitator Superfamily
H9L17_15130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9L17_15140	COG0025	NhaP-type Na H and K H
H9L17_15145	COG2610	gluconate transmembrane transporter activity
H9L17_15150	COG4771	TonB-dependent receptor
H9L17_15155	COG2205	protein histidine kinase activity
H9L17_15160	COG2197	response regulator
H9L17_15165	COG1530	ribonuclease E activity
H9L17_15175	COG2154	pterin-4-alpha-carbinolamine dehydratase
H9L17_15180	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H9L17_15180	COG0316	Belongs to the HesB IscA family
H9L17_15190	COG1742	UPF0060 membrane protein
H9L17_15205	COG0017	Asparaginyl-tRNA synthetase
H9L17_15210	COG0316	Belongs to the HesB IscA family
H9L17_15215	COG0360	Binds together with S18 to 16S ribosomal RNA
H9L17_15220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9L17_15225	COG0359	binds to the 23S rRNA
H9L17_15230	COG0305	Participates in initiation and elongation during chromosome replication
H9L17_15235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9L17_15280	COG0745	RESPONSE REGULATOR receiver
H9L17_15325	COG0492	ferredoxin-NADP+ reductase activity
H9L17_15330	COG0686	Belongs to the AlaDH PNT family
H9L17_15335	COG1674	ftsk spoiiie
H9L17_15345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9L17_15350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H9L17_15375	COG5001	Diguanylate cyclase
H9L17_15375	COG3300	MHYT domain
H9L17_15390	COG0840	transmembrane signaling receptor activity
H9L17_15400	COG0840	transmembrane signaling receptor activity
H9L17_15405	COG0835	chemotaxis
H9L17_15410	COG1960	acyl-CoA dehydrogenase activity
H9L17_15425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9L17_15425	COG1703	isobutyryl-CoA mutase activity
H9L17_15425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9L17_15485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9L17_15500	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_15570	COG3706	GGDEF domain
H9L17_15580	COG1131	(ABC) transporter
H9L17_15600	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H9L17_15690	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H9L17_15695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H9L17_15700	COG0813	purine-nucleoside phosphorylase activity
H9L17_15725	COG0204	Acyl-transferase
H9L17_15730	COG3038	cytochrome b561
H9L17_15745	COG0251	oxidation-reduction process
H9L17_15770	COG3590	peptidase
H9L17_15815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9L17_15830	COG4221	oxidoreductase activity