locus-tag	class	description
G7079_00010	ENOG4105CN1	protease
G7079_00020	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
G7079_00030	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
G7079_00035	ENOG4105DZ1	carboxypeptidase
G7079_00040	ENOG4105K6T	rare lipoprotein A
G7079_00045	ENOG4105CVE	Lytic murein transglycosylase
G7079_00050	ENOG4105CNI	cell division protein FtsW
G7079_00055	ENOG4105CJN	penicillin-binding protein
G7079_00065	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
G7079_00075	ENOG4107T4Z	adenosine kinase
G7079_00100	ENOG4105CD8	aminopeptidase N
G7079_00115	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G7079_00120	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
G7079_00125	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
G7079_00155	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
G7079_00195	ENOG4105DB1	molybdopterin oxidoreductase
G7079_00205	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G7079_00210	ENOG4105K8R	UPF0145 protein
G7079_00215	ENOG4108KDI	dmso reductase anchor subunit
G7079_00225	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
G7079_00230	ENOG4108NEV	two component transcriptional regulator, LytTR family
G7079_00275	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
G7079_00285	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7079_00290	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
G7079_00315	ENOG4105CMR	udp-glucose 4-epimerase
G7079_00320	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G7079_00335	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G7079_00340	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G7079_00345	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G7079_00350	ENOG4108WZM	domain protein
G7079_00360	ENOG4108RPN	Protein smg homolog
G7079_00365	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
G7079_00370	ENOG4108ZHJ	Organic hydroperoxide resistance protein
G7079_00375	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G7079_00390	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
G7079_00400	ENOG4107TDE	lipolytic protein G-D-S-L family
G7079_00405	ENOG4105CHR	reductase
G7079_00415	ENOG4105ETE	Transcriptional regulator (LacI family
G7079_00425	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G7079_00435	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G7079_00450	ENOG4105EBR	Carboxylesterase
G7079_00465	ENOG4105D07	Signal peptide peptidase, SppA
G7079_00470	ENOG4107QI1	Mate efflux family protein
G7079_00490	ENOG4105ENE	Histidine kinase
G7079_00510	ENOG4105C25	Primosomal protein n'
G7079_00515	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G7079_00525	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G7079_00530	ENOG4108IG5	Transcriptional regulator
G7079_00550	ENOG4105EN6	Membrane
G7079_00555	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7079_00560	ENOG4108FHP	Autotransporter beta-domain
G7079_00570	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
G7079_00580	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
G7079_00585	ENOG4105CAK	Cell division ATP-binding protein ftsE
G7079_00590	ENOG4105C1J	atp-dependent rna helicase
G7079_00595	ENOG4105K63	Thioredoxin
G7079_00600	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
G7079_00610	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G7079_00620	ENOG4105VNG	YcgL domain-containing protein
G7079_00625	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G7079_00630	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G7079_00640	ENOG4105DZ0	fad dependent oxidoreductase
G7079_00645	ENOG4105CHU	acetyl-coa acetyltransferase
G7079_00685	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G7079_00690	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G7079_00695	ENOG4105CUX	Signal transduction histidine kinase
G7079_00720	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G7079_00735	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
G7079_00745	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
G7079_00750	ENOG4105CBC	glutamate synthase
G7079_00755	ENOG4105BZ8	glutamate synthase
G7079_00770	ENOG4107SET	aldo keto reductase
G7079_00780	ENOG4105EQ2	LysR family Transcriptional regulator
G7079_00785	ENOG4105CPC	Aldo Keto reductase
G7079_00820	ENOG4105BZU	Histidine kinase
G7079_00825	ENOG4108YZA	Nitrogen regulatory protein pii
G7079_00835	ENOG4105C5F	glutamine synthetase
G7079_00840	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G7079_00855	ENOG4105E5G	Alpha beta hydrolase fold
G7079_00860	ENOG4108Z20	Acyl-transferase
G7079_00865	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
G7079_00875	ENOG4107RZC	phospholipase d
G7079_00890	ENOG4105BZU	Histidine kinase
G7079_00895	ENOG4105BZU	Histidine kinase
G7079_00930	ENOG4105EUJ	GTP cyclohydrolase i
G7079_00970	ENOG4105CIS	alcohol dehydrogenase
G7079_00975	ENOG4108VKG	metal-dependent hydrolase
G7079_00980	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
G7079_00995	ENOG41082BM	Transcriptional regulator, arsr family
G7079_01025	ENOG4107QKA	exodeoxyribonuclease V beta
G7079_01030	ENOG4105DSY	exodeoxyribonuclease V, gamma
G7079_01035	ENOG4105DHJ	ABC, transporter
G7079_01040	ENOG4105CY3	ABC transporter, permease
G7079_01045	ENOG4107PE3	Mammalian cell entry related domain protein
G7079_01060	ENOG410903C	(LipO)protein
G7079_01065	ENOG4105CGY	Dna recombination protein
G7079_01075	ENOG4105DR4	Methyltransferase
G7079_01080	ENOG4105DU1	integral membrane protein, terc
G7079_01090	ENOG4108R5S	membrane
G7079_01095	ENOG4105D78	K07001 NTE family protein
G7079_01100	ENOG4105MIR	Phenylalanine 4-monooxygenase
G7079_01105	ENOG4105CHB	tonB-dependent Receptor
G7079_01115	ENOG4105BZU	Histidine kinase
G7079_01155	ENOG4105EUB	pirin domain protein
G7079_01165	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
G7079_01180	ENOG4105M8F	Biopolymer transport protein exbD tolR
G7079_01215	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7079_01220	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
G7079_01225	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
G7079_01240	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
G7079_01245	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G7079_01250	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
G7079_01265	ENOG4108IUW	ABC transporter
G7079_01295	ENOG4105DA5	(ABC) transporter
G7079_01300	ENOG4105E3A	(ABC) transporter
G7079_01305	ENOG4105F8V	Hydrolase, tatD family
G7079_01310	ENOG4105CQ7	ATP-dependent helicase
G7079_01320	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G7079_01325	ENOG4108R99	pseudouridine synthase
G7079_01335	ENOG4105E9K	Isocitrate dehydrogenase
G7079_01345	ENOG4109066	lysm domain bon superfamily protein
G7079_01350	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
G7079_01355	ENOG4105D6Z	AFG1 family ATPase
G7079_01360	ENOG4105DHZ	alpha beta
G7079_01370	ENOG4107GHC	outer membrane autotransporter
G7079_01410	ENOG4105MJ2	Competence protein
G7079_01415	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
G7079_01420	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G7079_01475	ENOG4105CFU	surface antigen
G7079_01480	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G7079_01490	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G7079_01525	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
G7079_01555	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G7079_01565	ENOG4105E55	glycerol-3-phosphate acyltransferase
G7079_01575	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
G7079_01580	ENOG4105C4R	Atp-dependent dna helicase
G7079_01585	ENOG4107104	thymidine kinase
G7079_01590	ENOG4105D9P	serine threonine protein kinase
G7079_01600	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
G7079_01615	ENOG4105F9F	transposase
G7079_01620	ENOG4105C9K	Endothelin-converting enzyme 1
G7079_01625	ENOG4105CSH	Transporter
G7079_01635	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G7079_01650	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G7079_01655	ENOG4105BZS	acriflavin resistance protein
G7079_01660	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G7079_01670	ENOG4105W0E	50S ribosomal protein L33
G7079_01675	ENOG4105KDC	50s ribosomal protein l28
G7079_01690	ENOG4105CKK	Glycosyl transferase, family 2
G7079_01695	ENOG4105FA0	parb-like partition protein
G7079_01700	ENOG4107QJE	Chromosome Partitioning Protein
G7079_01705	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
G7079_01725	ENOG4107RGH	Aldehyde dehydrogenase
G7079_01730	ENOG4108Z0R	Transferase
G7079_01740	ENOG4105D52	delta-aminolevulinic acid dehydratase
G7079_01755	ENOG4105CKK	Glycosyl transferase, family 2
G7079_01760	ENOG4105C5Z	peptidase
G7079_01765	ENOG4105CYM	Glutathione S-transferase
G7079_01770	ENOG4108TEB	UPF0114 protein
G7079_01775	ENOG4105C4R	Atp-dependent dna helicase
G7079_01780	ENOG4108W15	Protein of unknown function (DUF1456)
G7079_01800	ENOG4105BZ1	(ABC) transporter
G7079_01805	ENOG4105C2M	dna polymerase I
G7079_01810	ENOG4107VMU	Membrane
G7079_01815	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
G7079_01845	ENOG4107YZP	Rhodanese domain protein
G7079_01855	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
G7079_01870	ENOG4106F60	Histidine kinase
G7079_01880	ENOG4105E0M	Sulfatase
G7079_01895	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
G7079_01900	ENOG4108RU0	short-chain dehydrogenase reductase
G7079_01920	ENOG4105E2T	synthase III
G7079_01925	ENOG4108J2P	Alpha beta hydrolase fold
G7079_01935	ENOG4105PI0	Ferredoxin
G7079_01940	ENOG410680H	amp-dependent synthetase and ligase
G7079_01945	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
G7079_01955	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G7079_01960	ENOG4105DQ4	alcohol dehydrogenase
G7079_01970	ENOG4105DR9	pseudouridine synthase
G7079_01975	ENOG4108YZN	class I peptide chain release factor
G7079_01995	ENOG4105K64	Glycosyl transferase, family 2
G7079_02030	ENOG4105D44	asparaginase
G7079_02040	ENOG4107QP3	malate synthase g
G7079_02050	ENOG4105BZU	Histidine kinase
G7079_02070	ENOG4105C0P	Mg chelatase subunit ChlI
G7079_02075	ENOG4105W0Z	cytoplasmic protein
G7079_02080	ENOG4108YZA	Nitrogen regulatory protein pii
G7079_02095	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
G7079_02125	ENOG4105W5Q	DNA repair protein (RadC
G7079_02140	ENOG4107QKV	phosphomannomutase
G7079_02160	ENOG4108E7F	Transporter
G7079_02170	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
G7079_02175	ENOG4105DR5	peptidase
G7079_02180	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
G7079_02185	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7079_02270	ENOG4108426	dNA-binding protein
G7079_02290	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G7079_02295	ENOG41063SB	peptidase
G7079_02300	ENOG4105CN1	protease
G7079_02315	ENOG4105C26	Dehydrogenase
G7079_02335	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
G7079_02340	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
G7079_02360	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
G7079_02365	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
G7079_02370	ENOG4105CF1	Alkylated DNA repair protein
G7079_02375	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G7079_02380	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
G7079_02385	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
G7079_02405	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G7079_02410	ENOG4107ZVW	dihydroneopterin aldolase
G7079_02420	ENOG4105CHR	reductase
G7079_02440	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
G7079_02445	ENOG4107SC1	transglycosylase
G7079_02450	ENOG4105HF0	Membrane
G7079_02475	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
G7079_02480	ENOG4108IUK	alpha amylase, catalytic
G7079_02485	ENOG4105D1K	glutamate--cysteine ligase
G7079_02515	ENOG4108RMV	DegV Family
G7079_02525	ENOG4105CQM	Urea amidohydrolase subunit alpha
G7079_02560	ENOG4105CHM	Aminotransferase
G7079_02565	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
G7079_02575	ENOG4105C6K	Malic enzyme
G7079_02580	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
G7079_02595	ENOG4107S1E	Beta-lactamase
G7079_02605	ENOG4108R3E	Dna-3-methyladenine glycosylase i
G7079_02615	ENOG4105F27	Major Facilitator
G7079_02630	ENOG4108VAC	response regulator
G7079_02635	ENOG4105C2F	Histidine kinase
G7079_02640	ENOG4105BZU	Histidine kinase
G7079_02650	ENOG4105GRZ	Ycii-related protein
G7079_02655	ENOG4105GRZ	Ycii-related protein
G7079_02670	ENOG4105CHP	RNA polymerase
G7079_02700	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
G7079_02705	ENOG4105I08	Pseudouridine synthase
G7079_02720	ENOG4108VPT	UPF0234 protein
G7079_02725	ENOG4108EHX	EamA-like transporter family
G7079_02745	ENOG4107QSN	dihydrolipoamide acetyltransferase
G7079_02750	ENOG4105EGS	Mechanosensitive ion channel
G7079_02755	ENOG4107QN2	dihydrolipoyl dehydrogenase
G7079_02765	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
G7079_02770	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G7079_02775	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G7079_02795	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G7079_02800	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G7079_02815	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
G7079_02820	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
G7079_02900	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G7079_02990	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G7079_03015	ENOG4105BZS	acriflavin resistance protein
G7079_03020	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
G7079_03040	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
G7079_03050	ENOG4108UQY	Iron-storage protein
G7079_03055	ENOG4105BZU	Histidine kinase
G7079_03090	ENOG4107S74	Lysophospholipid transporter LplT
G7079_03095	ENOG4105D85	methylase
G7079_03120	ENOG4105D3G	Pseudouridine synthase
G7079_03125	ENOG41086VY	Fic/DOC family
G7079_03140	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
G7079_03150	ENOG4108I0Y	(ABC) transporter
G7079_03155	ENOG4108UJV	acyl-CoA thioesterase i
G7079_03160	ENOG4105C12	Phosphoribosylglycinamide synthetase
G7079_03170	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G7079_03175	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
G7079_03185	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G7079_03195	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G7079_03200	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
G7079_03205	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
G7079_03210	ENOG4107ZT5	Thiol disulfide interchange protein
G7079_03215	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
G7079_03220	ENOG4105VF7	tolerance protein
G7079_03225	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G7079_03245	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
G7079_03255	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
G7079_03260	ENOG4108YYC	ycei family
G7079_03285	ENOG4106WTF	Glycosyl transferase, family 2
G7079_03290	ENOG4105D1S	lipid A biosynthesis
G7079_03295	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G7079_03300	ENOG4105DFG	type I secretion outer membrane protein
G7079_03305	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G7079_03310	ENOG4108IG5	Transcriptional regulator
G7079_03325	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G7079_03340	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G7079_03345	ENOG4105C7B	Threonine dehydratase
G7079_03350	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G7079_03365	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
G7079_03390	ENOG4105F0N	pyrophosphate phospho-hydrolase
G7079_03395	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G7079_03405	ENOG41063C6	UPF0235 protein
G7079_03420	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G7079_03425	ENOG4105DFU	Cell wall formation (By similarity)
G7079_03435	ENOG410841Q	phosphoesterase PA-phosphatase related protein
G7079_03440	ENOG4105CHR	reductase
G7079_03445	ENOG4105GFR	rna polymerase sigma factor
G7079_03460	ENOG4108UYE	Lactoylglutathione lyase
G7079_03465	ENOG4105C8Y	Acetylornithine aminotransferase
G7079_03475	ENOG4105EYW	Ion transport protein
G7079_03480	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
G7079_03485	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
G7079_03490	ENOG4105VCQ	rubredoxin
G7079_03525	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G7079_03545	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G7079_03555	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
G7079_03565	ENOG4105BZU	Histidine kinase
G7079_03570	ENOG4105E07	UPF0149 protein
G7079_03575	ENOG4107RAQ	aminopeptidase
G7079_03580	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
G7079_03595	ENOG4105CSA	Coproporphyrinogen iii oxidase
G7079_03600	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
G7079_03605	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
G7079_03610	ENOG4105DSJ	YicC domain protein
G7079_03625	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G7079_03630	ENOG4105KME	endoribonuclease L-psp
G7079_03635	ENOG4105CB5	ATP-dependent DNA helicase recG
G7079_03650	ENOG4105BZN	citrate synthase
G7079_03665	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7079_03670	ENOG41062D9	Histidine kinase
G7079_03680	ENOG4108JQC	penicillin-binding protein 1A
G7079_03705	ENOG4105E4G	Type IV pilus
G7079_03710	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G7079_03750	ENOG4105CYC	Transferase
G7079_03795	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G7079_03825	ENOG4105CA9	Pyruvate kinase
G7079_03830	ENOG4107R1Y	fructose-bisphosphate aldolase
G7079_03845	ENOG4105BZS	acriflavin resistance protein
G7079_03850	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G7079_03860	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G7079_03885	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
G7079_03890	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G7079_03910	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
G7079_03915	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
G7079_03920	ENOG4105ETX	regulatoR
G7079_03925	ENOG4105DHQ	Histidine kinase
G7079_03930	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G7079_03940	ENOG4105SYT	Methylenetetrahydrofolate reductase
G7079_03950	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G7079_03970	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G7079_03980	ENOG4108RVA	ribokinase
G7079_03985	ENOG4105D9N	nucleoside
G7079_04000	ENOG4105CPC	Aldo Keto reductase
G7079_04020	ENOG4105EMN	RNA polymerase sigma factor
G7079_04025	ENOG4107QX8	SPFH domain, Band 7 family protein
G7079_04040	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
G7079_04045	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
G7079_04065	ENOG4108V0P	LemA family
G7079_04070	ENOG4105D0M	Protease HtpX homolog
G7079_04105	ENOG4105KA3	membrAne
G7079_04115	ENOG4107QPN	acyl-Coa dehydrogenase
G7079_04125	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
G7079_04130	ENOG4108KPZ	tonB-dependent Receptor
G7079_04140	ENOG4108KPZ	tonB-dependent Receptor
G7079_04145	ENOG4105EMN	RNA polymerase sigma factor
G7079_04165	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
G7079_04170	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
G7079_04185	ENOG4108UT2	hemolysin iii
G7079_04190	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
G7079_04200	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
G7079_04205	ENOG4105C28	cystathionine
G7079_04210	ENOG4105CFH	Aspartokinase
G7079_04215	ENOG4105BZU	Histidine kinase
G7079_04220	ENOG4105EJQ	L-serine dehydratase
G7079_04235	ENOG4105DS1	cytochrome b561
G7079_04240	ENOG4108YYC	ycei family
G7079_04245	ENOG4105BZU	Histidine kinase
G7079_04250	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
G7079_04260	ENOG4105D49	3-dehydroquinate synthase
G7079_04265	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G7079_04275	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
G7079_04280	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
G7079_04295	ENOG4105II7	pyrroline-5-carboxylate reductase
G7079_04300	ENOG4105DFA	alanine racemase domain protein
G7079_04305	ENOG4105CZX	twitching motility protein
G7079_04310	ENOG4105CZX	twitching motility protein
G7079_04315	ENOG4108UJU	UPF0301 protein
G7079_04320	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G7079_04330	ENOG4105CJW	magnesium transporter
G7079_04335	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G7079_04340	ENOG41080Z8	PHOSPHOCARRIER protein
G7079_04350	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G7079_04360	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
G7079_04365	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7079_04370	ENOG4108IUZ	ABC transporter
G7079_04385	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
G7079_04390	ENOG4105C2X	Arabinose 5-phosphate isomerase
G7079_04405	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
G7079_04415	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G7079_04420	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G7079_04430	ENOG4105C02	permease
G7079_04435	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
G7079_04440	ENOG4108S0S	Nucleotidyl transferase
G7079_04445	ENOG4105EHM	Aminoglycoside phosphotransferase
G7079_04460	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G7079_04465	ENOG4107R11	Transcriptional regulator
G7079_04470	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
G7079_04475	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
G7079_04480	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
G7079_04485	ENOG4105Y3U	Transglycosylase-associated protein
G7079_04510	ENOG4108ESX	Receptor
G7079_04515	ENOG4105VQD	rieske 2fe-2S domain-containing protein
G7079_04520	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
G7079_04525	ENOG4105C9B	Cysteine desulfurase
G7079_04535	ENOG4105C3K	feS assembly ATPase SufC
G7079_04545	ENOG4105UFH	BadM Rrf2 family transcriptional regulator
G7079_04580	ENOG4105FAA	peptidase M23
G7079_04585	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G7079_04590	ENOG4108Z9K	Osmotically inducible protein
G7079_04600	ENOG4105JAB	phenazine biosynthesis protein, phzf family
G7079_04605	ENOG4105JAB	phenazine biosynthesis protein, phzf family
G7079_04610	ENOG4105CFH	Aspartokinase
G7079_04620	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
G7079_04630	ENOG4105EAH	synthase
G7079_04650	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
G7079_04675	ENOG4105F6J	Alpha beta hydrolase fold
G7079_04710	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
G7079_04725	ENOG4105C29	acyl-CoA thioesterase
G7079_04740	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
G7079_04750	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
G7079_04765	ENOG4105CSU	acyl-Coa dehydrogenase
G7079_04790	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
G7079_04795	ENOG4105CEN	a g-specific adenine glycosylase
G7079_04805	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
G7079_04810	ENOG4106H78	methyltransferase
G7079_04825	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
G7079_04835	ENOG4105C8F	Beta-lactamase domain protein
G7079_04840	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
G7079_04855	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G7079_04860	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
G7079_04865	ENOG4105VIE	preprotein translocase, subunit YajC
G7079_04870	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G7079_04875	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G7079_04895	ENOG4105BZU	Histidine kinase
G7079_04915	ENOG4105CJ3	phosphate transporter
G7079_04940	ENOG4105DUX	Transporter
G7079_04945	ENOG4105EPD	Oligopeptide transporter, Opt family
G7079_04950	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
G7079_04970	ENOG4108JU5	Magnesium and cobalt efflux protein
G7079_04975	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
G7079_04980	ENOG4105C9A	Phoh family
G7079_04985	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
G7079_04995	ENOG4105CJ1	ABC, transporter
G7079_05000	ENOG4107QWP	ABC-2 type transporter
G7079_05015	ENOG4105E4C	Lytic transglycosylase catalytic
G7079_05020	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G7079_05025	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G7079_05030	ENOG4105EIX	cytochrome c1
G7079_05035	ENOG4107MKT	Stringent starvation protein a
G7079_05040	ENOG4105KB2	stringent starvation protein b
G7079_05055	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
G7079_05060	ENOG4105W49	UPF0434 protein
G7079_05065	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
G7079_05070	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G7079_05080	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G7079_05085	ENOG4105M2J	Glutaredoxin
G7079_05095	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
G7079_05100	ENOG4108KPZ	tonB-dependent Receptor
G7079_05105	ENOG4105EWT	decarboxylase family
G7079_05110	ENOG4108HRK	Histidine kinase
G7079_05115	ENOG4105KHS	type IV fimbrial pilin protein
G7079_05145	ENOG4105C0H	protease
G7079_05180	ENOG4108K01	transcriptional regulator
G7079_05190	ENOG4105EUB	pirin domain protein
G7079_05200	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
G7079_05205	ENOG4105FFC	UPF0187 protein
G7079_05220	ENOG4105EZR	dyp-type peroxidase family protein
G7079_05225	ENOG4105DVC	DnaJ domain protein
G7079_05250	ENOG4105F9F	transposase
G7079_05295	ENOG4105F9F	transposase
G7079_05320	ENOG4107RRE	RNA-directed DNA polymerase
G7079_05325	ENOG4105DFP	Integrase
G7079_05345	ENOG4109066	lysm domain bon superfamily protein
G7079_05375	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G7079_05390	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
G7079_05395	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G7079_05420	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G7079_05425	ENOG4105C9K	Endothelin-converting enzyme 1
G7079_05440	ENOG4105CY0	Metallo-Beta-Lactamase
G7079_05460	ENOG4105C1J	atp-dependent rna helicase
G7079_05485	ENOG4107QR8	Thioredoxin
G7079_05515	ENOG4105W3H	MtN3 and saliva related transmembrane protein
G7079_05525	ENOG4105C8T	Leucyl-tRNA synthetase
G7079_05540	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
G7079_05560	ENOG4105MPN	Membrane
G7079_05565	ENOG4108Z03	MAF-like protein
G7079_05570	ENOG4105C03	ribonuclease
G7079_05580	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
G7079_05590	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
G7079_05605	ENOG4105CTB	Polyprenyl synthetase
G7079_05615	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G7079_05635	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G7079_05640	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G7079_05645	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G7079_05650	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
G7079_05655	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G7079_05660	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7079_05665	ENOG4105DZP	Membrane-associated zinc metalloprotease
G7079_05670	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
G7079_05675	ENOG4105KNE	Phosphatidate cytidylyltransferase
G7079_05680	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G7079_05705	ENOG4105CE9	30S ribosomal protein S2
G7079_05710	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G7079_05715	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
G7079_05725	ENOG4105KUZ	arsenate reductase
G7079_05730	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G7079_05735	ENOG4105CAQ	asparagine synthetase
G7079_05740	ENOG4105FQ6	thiopurine methyltransferase
G7079_05745	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7079_05785	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
G7079_05800	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
G7079_05805	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
G7079_05820	ENOG4105CEI	nitrite reductase
G7079_05855	ENOG4105DSQ	Nitric oxide reductase
G7079_05860	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
G7079_05865	ENOG4105D4P	Coproporphyrinogen iii oxidase
G7079_05880	ENOG4105F4R	Transcriptional regulator mode
G7079_05885	ENOG4105GAV	receptor
G7079_05895	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
G7079_05900	ENOG4105E0C	molybdate abc transporter
G7079_05910	ENOG4108V9Q	carbonic anhydrase
G7079_05925	ENOG4105CQB	FAD linked oxidase domain protein
G7079_05930	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G7079_05935	ENOG41076YT	nitrate reductase, gamma subunit
G7079_05940	ENOG4105R3A	Nitrate reductase
G7079_05945	ENOG4108IUE	nitrate reductase beta subunit
G7079_05950	ENOG4105CRU	nitrate reductase, alpha subunit
G7079_05960	ENOG4108ZAF	Molybdopterin
G7079_05970	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G7079_05975	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G7079_05980	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G7079_05995	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G7079_06000	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G7079_06015	ENOG4105E18	UPF0276 protein
G7079_06025	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
G7079_06030	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G7079_06035	ENOG4105E2Z	phosphate ABC transporter (Permease
G7079_06040	ENOG4105C8U	phosphate abc transporter
G7079_06045	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
G7079_06060	ENOG4105CSM	endonuclease III
G7079_06070	ENOG4105E39	Enoyl-CoA hydratase
G7079_06105	ENOG4108TGP	Thioesterase superfamily protein
G7079_06110	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G7079_06120	ENOG4105K46	50S ribosomal protein l27
G7079_06125	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7079_06135	ENOG4105CJR	Integral membrane protein (MviN
G7079_06140	ENOG4105DTN	riboflavin biosynthesis protein ribF
G7079_06150	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G7079_06155	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G7079_06175	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G7079_06185	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G7079_06190	ENOG4105CW7	secretion protein, HlyD family
G7079_06195	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
G7079_06200	ENOG41090HR	transcriptional regulator
G7079_06210	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G7079_06215	ENOG4105K5M	30s ribosomal protein S16
G7079_06220	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G7079_06225	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
G7079_06235	ENOG4105VEJ	Heat shock protein
G7079_06245	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
G7079_06255	ENOG4105D29	Helix-turn-helix type 11 domain protein
G7079_06270	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
G7079_06280	ENOG4107TH8	cina domain protein
G7079_06285	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
G7079_06290	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G7079_06295	ENOG4105Y3E	Modulates RecA activity (By similarity)
G7079_06300	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G7079_06305	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
G7079_06320	ENOG4105ETE	Transcriptional regulator (LacI family
G7079_06335	ENOG4105CG3	alpha amylase, catalytic region
G7079_06360	ENOG4107RUZ	Sss sodium solute transporter superfamily
G7079_06365	ENOG4108UHU	Aldolase
G7079_06370	ENOG4105CHC	glucokinase (EC 2.7.1.2)
G7079_06375	ENOG4105C01	Dihydroxy-acid dehydratase
G7079_06405	ENOG4105DWF	phosphomethylpyrimidine kinase
G7079_06415	ENOG4108IAB	Phoh family
G7079_06420	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7079_06430	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G7079_06440	ENOG4108Z4U	Ferredoxin
G7079_06450	ENOG4105DJ0	Poly(A) Polymerase
G7079_06455	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G7079_06460	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
G7079_06465	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
G7079_06470	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
G7079_06475	ENOG4107QP8	phosphohexose isomerase
G7079_06480	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
G7079_06485	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G7079_06490	ENOG4105K8N	protein family UPF0079, ATPase
G7079_06495	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
G7079_06500	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
G7079_06515	ENOG4108R3D	Electron transport complex
G7079_06520	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G7079_06540	ENOG4105DHP	deoxycytidine triphosphate deaminase
G7079_06595	ENOG4108RRZ	Transcription elongation factor GreB
G7079_06605	ENOG4105D7A	ATP-binding protein
G7079_06615	ENOG4105DJ4	phosphatidylserine decarboxylase
G7079_06625	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
G7079_06630	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
G7079_06635	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
G7079_06645	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
G7079_06670	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
G7079_06675	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G7079_06730	ENOG4108TGY	Glutathione S-transferase
G7079_06735	ENOG4105DUX	Transporter
G7079_06750	ENOG4105FE9	pseudouridine synthase
G7079_06755	ENOG4105VEQ	Cold shock protein
G7079_06765	ENOG4107QRT	dEAD DEAH box helicase
G7079_06770	ENOG4105DGW	oligopeptidase A
G7079_06790	ENOG4105DP0	ferredoxin-NADP reductase
G7079_06800	ENOG4105D8V	Glucose sorbosone dehydrogenase
G7079_06840	ENOG4105CUZ	uba thif-type nad fad binding protein
G7079_06845	ENOG4105F8V	Hydrolase, tatD family
G7079_06860	ENOG4105C1G	acyl-Coa dehydrogenase
G7079_06870	ENOG4105CPP	Dehydrogenase, E1 component
G7079_06880	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
G7079_06890	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
G7079_06920	ENOG4105D60	lipoprotein releasing system transmembrane protein
G7079_06925	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G7079_06930	ENOG4108EC8	DNA internalization-related competence protein ComEC
G7079_06940	ENOG4105M8F	Biopolymer transport protein exbD tolR
G7079_06945	ENOG4105BZ1	(ABC) transporter
G7079_06950	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
G7079_06960	ENOG4105KJF	protein tyrosine phosphatase
G7079_06965	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
G7079_06970	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
G7079_06990	ENOG4105CBC	glutamate synthase
G7079_07000	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
G7079_07015	ENOG4107YJ4	chain length determinant protein
G7079_07020	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G7079_07045	ENOG4107QQG	Dehydrogenase
G7079_07070	ENOG4105BZF	Glycosyl transferase (Group 1
G7079_07080	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G7079_07085	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G7079_07095	ENOG4105C5E	polysaccharide biosynthesis protein
G7079_07100	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G7079_07110	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
G7079_07130	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
G7079_07165	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
G7079_07190	ENOG4105BZ1	(ABC) transporter
G7079_07195	ENOG4105ESV	Glycosyl transferase, family 4
G7079_07220	ENOG4105PDP	Short chain dehydrogenase
G7079_07255	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
G7079_07260	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
G7079_07275	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G7079_07280	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G7079_07310	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G7079_07335	ENOG4105DU6	RNA polymerase
G7079_07350	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G7079_07370	ENOG4105WH1	Two component transcriptional regulator luxr family
G7079_07375	ENOG4107QQB	Ribonuclease E
G7079_07380	ENOG4105EI2	Pseudouridine synthase
G7079_07390	ENOG41090A4	Pterin carbinolamine dehydratase
G7079_07395	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
G7079_07420	ENOG4106RE7	Cytochrome
G7079_07425	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
G7079_07460	ENOG4105DWY	Agmatine deiminase
G7079_07470	ENOG4105YK5	50S ribosomal protein L36
G7079_07475	ENOG4105CAT	Cytidine monophosphate kinase
G7079_07480	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G7079_07485	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G7079_07495	ENOG4105CFV	Tetratricopeptide repeat protein
G7079_07510	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G7079_07515	ENOG4105CHU	acetyl-coa acetyltransferase
G7079_07530	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
G7079_07535	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
G7079_07545	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
G7079_07555	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
G7079_07560	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G7079_07565	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
G7079_07570	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G7079_07575	ENOG4105D06	uba thif-type nad fad binding protein
G7079_07595	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G7079_07600	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G7079_07605	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G7079_07610	ENOG4108R86	Transcriptional regulator
G7079_07630	ENOG4108Z6B	deaminase
G7079_07640	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
G7079_07645	ENOG4106TD9	Diguanylate cyclase
G7079_07660	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
G7079_07665	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
G7079_07710	ENOG4105WMR	Protein CrcB homolog
G7079_07715	ENOG4105D1H	recombination factor protein RarA
G7079_07730	ENOG4105CNU	cell division protein FtsK
G7079_07735	ENOG4105C3M	thioredoxin reductase
G7079_07745	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
G7079_07755	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7079_07760	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
G7079_07770	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G7079_07775	ENOG41075W9	High frequency lysogenization protein HflD homolog
G7079_07780	ENOG4105EYF	MMPL domain protein
G7079_07785	ENOG4105F9F	transposase
G7079_07790	ENOG4107QIJ	Aconitate hydratase 2
G7079_07805	ENOG4107QM5	aconitate hydratase
G7079_07815	ENOG4105CEY	Amp-dependent synthetase and ligase
G7079_07820	ENOG4105E39	Enoyl-CoA hydratase
G7079_07825	ENOG4105BZU	Histidine kinase
G7079_07830	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G7079_07850	ENOG4105EDV	vault protein
G7079_07855	ENOG4105DY9	regulatoR
G7079_07865	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G7079_07875	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
G7079_07880	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G7079_07885	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G7079_07890	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
G7079_07905	ENOG4105CFG	Acts as a chaperone (By similarity)
G7079_07915	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
G7079_07925	ENOG41090R7	Ferric uptake
G7079_07930	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
G7079_07935	ENOG4105VDB	UPF0125 protein
G7079_07940	ENOG4108Z1B	Cyclase dehydrase
G7079_07950	ENOG4105BZU	Histidine kinase
G7079_07960	ENOG4105CDV	Ompa motb domain protein
G7079_07980	ENOG4105CDU	Replicative dna helicase
G7079_07990	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G7079_07995	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
G7079_08000	ENOG4108Z4V	iron-sulfur cluster assembly
G7079_08005	ENOG4105C5S	asparaginyl-tRNA synthetase
G7079_08020	ENOG4105CHR	reductase
G7079_08030	ENOG41077A9	carbonic anhydrase
G7079_08040	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
G7079_08055	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
G7079_08060	ENOG4105CJB	Exodeoxyribonuclease I
G7079_08075	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G7079_08080	ENOG4105C7I	Dehydrogenase
G7079_08085	ENOG4105C1G	acyl-Coa dehydrogenase
G7079_08095	ENOG4105C3R	Methionine synthase
G7079_08100	ENOG4105C3R	Methionine synthase
G7079_08105	ENOG4105D8G	Major Facilitator superfamily
G7079_08115	ENOG41069P5	Protein slyX homolog
G7079_08120	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G7079_08125	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G7079_08130	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G7079_08135	ENOG4108V06	Glutathione peroxidase
G7079_08145	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
G7079_08150	ENOG4105CIG	ABC transporter
G7079_08180	ENOG4107QTF	adenylosuccinate lyase
G7079_08190	ENOG4105EZE	Cupin 4 family protein
G7079_08200	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
G7079_08205	ENOG4105C7S	Dehydrogenase
G7079_08220	ENOG4108URH	decarboxylase
G7079_08230	ENOG4105M3Z	response regulator
G7079_08245	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7079_08260	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
G7079_08265	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G7079_08270	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
G7079_08285	ENOG4105K9H	YciI-like protein
G7079_08300	ENOG4105FE9	pseudouridine synthase
G7079_08305	ENOG4105EUB	pirin domain protein
G7079_08320	ENOG4108YYH	Nadph-dependent fmn reductase
G7079_08325	ENOG4105CNM	Receptor
G7079_08335	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
G7079_08340	ENOG4105CHM	Aminotransferase
G7079_08345	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
G7079_08350	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
G7079_08375	ENOG4105N7H	Cytochrome
G7079_08385	ENOG41060IM	Heme exporter protein
G7079_08395	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
G7079_08410	ENOG4105KWW	Biogenesis protein
G7079_08415	ENOG4108M1T	Cytochrome c-type biogenesis protein
G7079_08420	ENOG4105DWV	Homoserine O-trans-acetylase
G7079_08440	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G7079_08450	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G7079_08470	ENOG4105BZU	Histidine kinase
G7079_08480	ENOG4105CY2	Citrate transporter
G7079_08490	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G7079_08500	ENOG4105CSH	Transporter
G7079_08505	ENOG4105BZM	domain protein
G7079_08510	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
G7079_08525	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G7079_08530	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G7079_08535	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G7079_08540	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
G7079_08560	ENOG4105CHV	Transcription elongation factor NusA
G7079_08565	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G7079_08575	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7079_08580	ENOG4105C8S	subunit m
G7079_08585	ENOG4105D65	subunit l
G7079_08595	ENOG4105DF2	NADH dehydrogenase subunit j
G7079_08600	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7079_08605	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
G7079_08610	ENOG4108IEH	NADH dehydrogenase subunit g
G7079_08615	ENOG4107QIZ	NADH dehydrogenase
G7079_08620	ENOG4105GKE	subunit e
G7079_08625	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7079_08635	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7079_08640	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G7079_08645	ENOG4105C5H	ABC transporter
G7079_08650	ENOG4105CNG	UPF0061 protein
G7079_08665	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G7079_08670	ENOG4105CBX	hi0933 family
G7079_08680	ENOG4105C72	UPF0176 protein
G7079_08685	ENOG4106V2I	dimethylaminohydrolase
G7079_08710	ENOG4105KSC	Transcriptional regulator, TraR DksA family
G7079_08715	ENOG4105BZU	Histidine kinase
G7079_08720	ENOG410620I	Diguanylate cyclase
G7079_08765	ENOG4105M4H	endoribonuclease L-psp
G7079_08780	ENOG4105CPW	cytochrome b561
G7079_08800	ENOG4106HNH	Acyl-transferase
G7079_08805	ENOG4105BZU	Histidine kinase
G7079_08815	ENOG4105BZU	Histidine kinase
G7079_08820	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
G7079_08895	ENOG4105E18	UPF0276 protein
G7079_08925	ENOG4105WJ3	XRE family Transcriptional regulator
G7079_08935	ENOG4105D5P	Methylmalonyl-coA mutase
G7079_08940	ENOG4107RZC	phospholipase d
G7079_08960	ENOG4105C1G	acyl-Coa dehydrogenase
G7079_08970	ENOG4105CHU	acetyl-coa acetyltransferase
G7079_08985	ENOG4107QX3	carboxylase
G7079_09010	ENOG4105CE1	Ferrous iron transport protein b
G7079_09020	ENOG41060WC	Enoyl-CoA hydratase
G7079_09025	ENOG4105DWY	Agmatine deiminase
G7079_09040	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
G7079_09045	ENOG4105BZU	Histidine kinase
G7079_09065	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G7079_09075	ENOG4105CQB	FAD linked oxidase domain protein
G7079_09080	ENOG4108JQ1	Dehydrogenase
G7079_09090	ENOG4105CUB	amino acid
G7079_09095	ENOG4107W7X	Aldolase
G7079_09100	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
G7079_09110	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
G7079_09120	ENOG4105BZU	Histidine kinase
G7079_09125	ENOG4105C84	Histidine ammonia-lyase
G7079_09130	ENOG4105CUT	histidyl-tRNA synthetase
G7079_09140	ENOG4105BZU	Histidine kinase
G7079_09145	ENOG4106R49	Methyltransferase
G7079_09225	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7079_09235	ENOG4105CS6	Rhs element vgr protein
G7079_09260	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G7079_09265	ENOG4105BZU	Histidine kinase
G7079_09270	ENOG4105IB0	filamentous hemagglutinin family outer membrane protein
G7079_09285	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G7079_09290	ENOG4105CH7	arginosuccinase
G7079_09295	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
G7079_09300	ENOG4105CAS	nag kinase
G7079_09310	ENOG4105CDH	Citrulline--aspartate ligase
G7079_09315	ENOG4105DBV	ornithine carbamoyltransferase
G7079_09350	ENOG4105CD3	dihydroorotase
G7079_09360	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
G7079_09370	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G7079_09380	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G7079_09390	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
G7079_09395	ENOG4108K0B	C-di-gmp phosphodiesterase
G7079_09405	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
G7079_09410	ENOG4105CHR	reductase
G7079_09415	ENOG4108NVM	synthesis repressor PhaR
G7079_09420	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G7079_09425	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G7079_09430	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
G7079_09440	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
G7079_09445	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G7079_09450	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
G7079_09485	ENOG4108UQS	dipeptidase
G7079_09500	ENOG4105DTQ	mandelate racemase muconate lactonizing
G7079_09510	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
G7079_09515	ENOG4105CFH	Aspartokinase
G7079_09540	ENOG4105C26	Dehydrogenase
G7079_09560	ENOG4108SXK	Transporter Drug Metabolite Exporter family
G7079_09565	ENOG410841Q	phosphoesterase PA-phosphatase related protein
G7079_09570	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
G7079_09575	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G7079_09590	ENOG4108MMM	RNA Polymerase
G7079_09600	ENOG4105BZ1	(ABC) transporter
G7079_09605	ENOG4105CMR	udp-glucose 4-epimerase
G7079_09615	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
G7079_09620	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
G7079_09625	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
G7079_09630	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
G7079_09640	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
G7079_09660	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
G7079_09670	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G7079_09680	ENOG4105C3F	Signal peptidase i
G7079_09690	ENOG4105C0H	protease
G7079_09700	ENOG4105EMN	RNA polymerase sigma factor
G7079_09705	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G7079_09715	ENOG4107QRG	dna polymerase iii
G7079_09720	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
G7079_09725	ENOG4105HHA	aminodeoxychorismate lyase
G7079_09730	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
G7079_09740	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G7079_09750	ENOG4105CHR	reductase
G7079_09755	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G7079_09760	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
G7079_09765	ENOG4105VGS	50s ribosomal protein l32
G7079_09770	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
G7079_09780	ENOG4108UHJ	MAF-like protein
G7079_09790	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G7079_09800	ENOG4105F8C	transglutaminase domain-containing protein
G7079_09810	ENOG4105K59	histidine triad (HIT) protein
G7079_09815	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
G7079_09820	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
G7079_09825	ENOG4107QMP	dna polymerase iii subunits gamma and tau
G7079_09875	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G7079_09885	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
G7079_09890	ENOG4105DKP	glycosyl transferase, family 9
G7079_09910	ENOG4107RZZ	dna polymerase iii epsilon subunit
G7079_09915	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G7079_09935	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G7079_09940	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G7079_09965	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G7079_09970	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G7079_09975	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G7079_10015	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G7079_10025	ENOG4105VW4	glutaredoxin 3
G7079_10030	ENOG4105ERG	peptidase m48, ste24p
G7079_10035	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7079_10040	ENOG4105BZU	Histidine kinase
G7079_10045	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
G7079_10050	ENOG4105C9X	ppx gppa phosphatase
G7079_10070	ENOG4105CZV	ABC transporter
G7079_10075	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
G7079_10080	ENOG4105BZF	Glycosyl transferase (Group 1
G7079_10085	ENOG4105EYK	Phosphatidylglycerophosphatase B
G7079_10105	ENOG4105CT7	inner membrane cred family protein
G7079_10110	ENOG4105EB3	Histidine kinase
G7079_10115	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G7079_10120	ENOG4105D6S	protein involved in catabolism of external DNA
G7079_10130	ENOG4105CKW	Inner membrane protein yedI
G7079_10140	ENOG4108JA2	transcriptioN-repair coupling factor
G7079_10145	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
G7079_10365	ENOG4105WH1	Two component transcriptional regulator luxr family
G7079_10370	ENOG4105BZU	Histidine kinase
G7079_10380	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
G7079_10385	ENOG4107QMS	site-determining protein
G7079_10390	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
G7079_10415	ENOG4105D5Q	Arginine ornithine antiporter
G7079_10435	ENOG4105D9P	serine threonine protein kinase
G7079_10440	ENOG4105BZU	Histidine kinase
G7079_10445	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7079_10455	ENOG4105CD8	aminopeptidase N
G7079_10475	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G7079_10485	ENOG4105EPW	hflc protein
G7079_10490	ENOG4107QJR	hflk protein
G7079_10495	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G7079_10500	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
G7079_10505	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G7079_10510	ENOG4105CUB	amino acid
G7079_10525	ENOG4105EEI	dihydropteroate synthase
G7079_10530	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G7079_10535	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
G7079_10540	ENOG4105HBR	Rna-binding protein
G7079_10550	ENOG4108K5P	(LipO)protein
G7079_10555	ENOG4108UM1	dedA family
G7079_10565	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
G7079_10575	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
G7079_10585	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
G7079_10595	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G7079_10600	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
G7079_10610	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7079_10625	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G7079_10630	ENOG4108YZY	peptidylprolyl cis-trans isomerase
G7079_10635	ENOG4105K4H	Nlp p60 protein
G7079_10640	ENOG4105K4H	Nlp p60 protein
G7079_10665	ENOG4105G6Z	alkaline phosphatase
G7079_10670	ENOG4108JJA	ABC, transporter
G7079_10690	ENOG4108MBX	Secretion Protein
G7079_10700	ENOG4108YXA	Membrane
G7079_10735	ENOG4107ZSV	Receptor
G7079_10740	ENOG4107RDJ	Sulfotransferase
G7079_10760	ENOG4105M3Z	response regulator
G7079_10765	ENOG4105FQP	Beta-lactamase
G7079_10780	ENOG4105HP8	regulator of competence-specific genes
G7079_10845	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
G7079_10850	ENOG4107QS8	(LipO)protein
G7079_10855	ENOG4105C1J	atp-dependent rna helicase
G7079_10875	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
G7079_10900	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
G7079_10920	ENOG4105CGP	Urocanate hydratase
G7079_10940	ENOG4105CI2	imidazolone-5-propionate hydrolase
G7079_10970	ENOG4108P3C	
G7079_10980	ENOG4105MYN	Zinc uptake regulation protein
G7079_10985	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G7079_10990	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
G7079_11000	ENOG4105ED9	Protein of unknown function (DUF455)
G7079_11005	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G7079_11015	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G7079_11020	ENOG4105CVJ	phosphoglycerate mutase
G7079_11045	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G7079_11050	ENOG4108R99	pseudouridine synthase
G7079_11060	ENOG4105UYK	outer membrane protein a
G7079_11065	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G7079_11075	ENOG4108K3A	Glutathione S-transferase
G7079_11080	ENOG4105BZN	citrate synthase
G7079_11085	ENOG4105CR4	methylisocitrate lyase
G7079_11095	ENOG4107RFB	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G7079_11105	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
G7079_11140	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
G7079_11145	ENOG4105CI3	gtp-binding protein typa
G7079_11165	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
G7079_11170	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
G7079_11175	ENOG4108ZT0	50S ribosomal protein l17
G7079_11185	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G7079_11200	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
G7079_11205	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
G7079_11215	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G7079_11220	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
G7079_11230	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G7079_11240	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7079_11255	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
G7079_11260	ENOG41083MP	50s ribosomal protein l29
G7079_11265	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
G7079_11270	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
G7079_11280	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G7079_11285	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7079_11290	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
G7079_11295	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G7079_11300	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G7079_11305	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G7079_11310	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G7079_11320	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
G7079_11325	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G7079_11330	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7079_11340	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G7079_11355	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G7079_11360	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
G7079_11365	ENOG4105PM1	preprotein translocase subunit SecE
G7079_11375	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G7079_11395	ENOG4105C3G	gtp-binding protein
G7079_11400	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
G7079_11410	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G7079_11430	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
G7079_11435	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
G7079_11440	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G7079_11445	ENOG4105KD7	acetyltransferase
G7079_11450	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
G7079_11460	ENOG4105CSR	polyphosphate kinase 2
G7079_11470	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7079_11475	ENOG4107S2Z	UPF0761 membrane protein
G7079_11480	ENOG4105CS1	NAD(P)H quinone oxidoreductase
G7079_11490	ENOG4107RDJ	Sulfotransferase
G7079_11495	ENOG4105HDK	L-asparaginase
G7079_11500	ENOG4105D4Y	metalloprotease
G7079_11515	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G7079_11520	ENOG4105W8H	transhydrogenase (subunit alpha
G7079_11545	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G7079_11555	ENOG4105C2M	dna polymerase I
G7079_11590	ENOG4105C5Q	Transcriptional regulator
G7079_11615	ENOG4105CX6	glutaminyL-tRNA synthetase
G7079_11630	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
G7079_11635	ENOG4105D0A	hydroxylase
G7079_11645	ENOG4108WBT	adenosyltransferase
G7079_11655	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
G7079_11660	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G7079_11665	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G7079_11670	ENOG4108Z7R	Chaperone CsaA
G7079_11680	ENOG4105NWN	ApaG protein
G7079_11685	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
G7079_11690	ENOG4105IJJ	transcriptional regulator, crp fnr family
G7079_11705	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G7079_11715	ENOG4105HA9	of methanol dehydrogenase type
G7079_11720	ENOG4108V0P	LemA family
G7079_11725	ENOG4105EE5	Membrane protein terC
G7079_11730	ENOG41080IJ	Diacylglycerol kinase
G7079_11735	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G7079_11740	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G7079_11745	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
G7079_11750	ENOG4105DHQ	Histidine kinase
G7079_11770	ENOG4105DXN	mazG family
G7079_11775	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
G7079_11780	ENOG4107RK2	ADP-ribose diphosphatase NudE
G7079_11790	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
G7079_11800	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
G7079_11805	ENOG4105CBS	Chea signal transduction histidine kinase
G7079_11810	ENOG4105C8Q	Methyl-accepting chemotaxis
G7079_11815	ENOG4108ZGA	chew protein
G7079_11820	ENOG4105M3Z	response regulator
G7079_11825	ENOG4108UNF	response regulator
G7079_11830	ENOG4105D7Z	glutathione synthase
G7079_11845	ENOG41072GX	Peptidase M22 Glycoprotease
G7079_11855	ENOG4105DVT	helicase
G7079_11860	ENOG4105BZ4	penicillin-binding protein
G7079_11870	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G7079_11875	ENOG4105CQ7	ATP-dependent helicase
G7079_11900	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G7079_11915	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
G7079_11925	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G7079_11940	ENOG4105M8F	Biopolymer transport protein exbD tolR
G7079_11945	ENOG4105E02	MotA TolQ exbB proton channel
G7079_11950	ENOG4107YD3	Thioesterase
G7079_11955	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G7079_11960	ENOG4105DFH	Transport of potassium into the cell (By similarity)
G7079_11965	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
G7079_11970	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
G7079_12000	ENOG4105C9M	aspartyl-trna synthetase
G7079_12005	ENOG4105BZU	Histidine kinase
G7079_12020	ENOG4105C5H	ABC transporter
G7079_12025	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G7079_12030	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7079_12055	ENOG4105C34	Pseudouridine synthase
G7079_12060	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7079_12070	ENOG4105C4K	Nad synthetase
G7079_12075	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
G7079_12080	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
G7079_12085	ENOG4107TUY	Histidine kinase
G7079_12090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G7079_12110	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
G7079_12115	ENOG4105C30	Nad-dependent epimerase dehydratase
G7079_12125	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G7079_12135	ENOG4107XZA	Glycosyl transferase family 2
G7079_12150	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G7079_12165	ENOG4105K64	Glycosyl transferase, family 2
G7079_12175	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G7079_12180	ENOG4105JNK	Glycosyl transferase (Group 1
G7079_12185	ENOG4105CKK	Glycosyl transferase, family 2
G7079_12190	ENOG4107QHF	type ii secretion system protein e
G7079_12200	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
G7079_12210	ENOG4105M6F	mutator MutT protein
G7079_12215	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G7079_12220	ENOG4105DR5	peptidase
G7079_12235	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
G7079_12240	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G7079_12245	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
G7079_12250	ENOG4105CPF	Cell wall formation (By similarity)
G7079_12255	ENOG4105DFU	Cell wall formation (By similarity)
G7079_12260	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
G7079_12275	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
G7079_12280	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G7079_12285	ENOG4105CJN	penicillin-binding protein
G7079_12290	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
G7079_12295	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G7079_12300	ENOG4108V6E	Cell division protein mraZ
G7079_12330	ENOG41082RQ	UPF0102 protein
G7079_12335	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
G7079_12340	ENOG4107YIM	Involved in the transcription termination process (By similarity)
G7079_12345	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
G7079_12350	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G7079_12360	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G7079_12365	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G7079_12370	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
G7079_12380	ENOG4105HMI	Membrane
G7079_12385	ENOG4105C5H	ABC transporter
G7079_12390	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
G7079_12405	ENOG4105GVR	general secretion pathway protein D
G7079_12415	ENOG410678M	general secretion pathway protein M
G7079_12420	ENOG41090VX	general secretion pathway protein L
G7079_12425	ENOG4105UV2	general secretion pathway protein K
G7079_12430	ENOG41069G9	General secretion pathway protein J
G7079_12440	ENOG4105WMT	general secretion pathway protein h
G7079_12450	ENOG4105D7Q	type ii secretion system
G7079_12455	ENOG4107QHF	type ii secretion system protein e
G7079_12460	ENOG4108ETH	Formylglycinamide ribotide synthetase
G7079_12465	ENOG4105T95	Thiol disulfide interChange protein
G7079_12470	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G7079_12480	ENOG4108K5H	permease YjgP YjgQ family protein
G7079_12490	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G7079_12515	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G7079_12530	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
G7079_12550	ENOG4105DHJ	ABC, transporter
G7079_12565	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G7079_12585	ENOG4105BZJ	Electron transfer flavoprotein
G7079_12590	ENOG4105C10	Electron transfer flavoprotein
G7079_12595	ENOG4105CKK	Glycosyl transferase, family 2
G7079_12610	ENOG4105CHR	reductase
G7079_12615	ENOG4105CEY	Amp-dependent synthetase and ligase
G7079_12635	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G7079_12660	ENOG4105EY8	ABC transporter
G7079_12670	ENOG4105C28	cystathionine
G7079_12685	ENOG4108ZG0	Ompa motb domain protein
G7079_12690	ENOG4105CZX	twitching motility protein
G7079_12695	ENOG4108RXX	maleylacetoacetate isomerase
G7079_12720	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G7079_12725	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
G7079_12730	ENOG4108VWS	Yaeq family
G7079_12740	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
G7079_12745	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
G7079_12765	ENOG4105DK0	Indole-3-glycerol phosphate synthase
G7079_12770	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
G7079_12790	ENOG4105DYB	Isoaspartyl dipeptidase
G7079_12795	ENOG4107QYG	anthranilate phosphoribosyltransferase
G7079_12800	ENOG4105DDQ	anthranilate synthase
G7079_12810	ENOG4105CRQ	synthase (Component I)
G7079_12815	ENOG4107TE5	Lipid kinase
G7079_12830	ENOG4105C8V	SAICAR synthetase
G7079_12845	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
G7079_12860	ENOG4105F1J	Homogentisate 1,2-dioxygenase
G7079_12865	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
G7079_12875	ENOG4105EPC	oxidoreductase
G7079_12880	ENOG4107RDJ	Sulfotransferase
G7079_12895	ENOG4105E70	isomerase
G7079_12900	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
G7079_12905	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
G7079_12910	ENOG4105E98	transcriptional regulator DeoR family
G7079_12915	ENOG4105CE4	GlcNAc 6-P deacetylase
G7079_12920	ENOG4107QNK	)-transporter
G7079_12925	ENOG4105DUX	Transporter
G7079_12930	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
G7079_12940	ENOG4107RUY	(E1 component), alpha subunit
G7079_12945	ENOG4105CPP	Dehydrogenase, E1 component
G7079_12950	ENOG4107QSN	dihydrolipoamide acetyltransferase
G7079_12975	ENOG4105C31	Tryptophanyl-tRNA synthetase
G7079_13005	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G7079_13010	ENOG4108I5D	sulfate abc transporter
G7079_13020	ENOG4108IJ6	ABC transporter
G7079_13030	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
G7079_13035	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
G7079_13045	ENOG4105DP4	dak2 domain fusion protein ylov
G7079_13055	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
G7079_13060	ENOG4105E0F	Histidine kinase
G7079_13065	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G7079_13080	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G7079_13085	ENOG4108I0Z	Aconitate hydratase
G7079_13090	ENOG4105C7F	AcnD-accessory protein PrpF
G7079_13095	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
G7079_13130	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
G7079_13140	ENOG4105DCF	alanine dehydrogenase
G7079_13145	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
G7079_13150	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
G7079_13160	ENOG4105K78	MarR family Transcriptional regulator
G7079_13165	ENOG4105K4T	epimerase
G7079_13180	ENOG4105VEQ	Cold shock protein
G7079_13190	ENOG4105EUB	pirin domain protein
G7079_13195	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G7079_13225	ENOG4105C0H	protease
G7079_13245	ENOG4105DSF	transport protein
G7079_13250	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
G7079_13255	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G7079_13265	ENOG4108S01	response regulator
G7079_13270	ENOG4105BZU	Histidine kinase
G7079_13280	ENOG4108M15	ABC transporter
G7079_13285	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
G7079_13290	ENOG4105C19	ABC transporter
G7079_13295	ENOG4107RBB	ABC transporter, permease
G7079_13300	ENOG4107RBB	ABC transporter, permease
G7079_13310	ENOG4105FDR	Membrane
G7079_13315	ENOG4108XM1	transcriptional regulator AsnC family