locus-tag	class	description
G7079_00020	COG0321	lipoyl(octanoyl) transferase activity
G7079_00025	COG2921	Belongs to the UPF0250 family
G7079_00030	COG2203	Gaf domain
G7079_00030	COG2199	diguanylate cyclase activity
G7079_00030	COG2200	EAL domain
G7079_00035	COG1686	Belongs to the peptidase S11 family
G7079_00040	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G7079_00045	COG2951	lytic endotransglycosylase activity
G7079_00050	COG0772	Belongs to the SEDS family
G7079_00055	COG0768	penicillin binding
G7079_00065	COG1792	Involved in formation and maintenance of cell shape
G7079_00070	COG1077	Cell shape determining protein MreB Mrl
G7079_00075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7079_00100	COG0308	aminopeptidase N
G7079_00115	COG2226	methyltransferase
G7079_00120	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G7079_00130	COG1215	transferase activity, transferring glycosyl groups
G7079_00155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G7079_00175	COG1505	serine-type exopeptidase activity
G7079_00195	COG0243	molybdopterin cofactor binding
G7079_00205	COG0437	4 iron, 4 sulfur cluster binding
G7079_00210	COG0393	Putative heavy-metal-binding
G7079_00215	COG3302	dmso reductase anchor subunit
G7079_00225	COG0181	hydroxymethylbilane synthase activity
G7079_00275	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G7079_00285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G7079_00290	COG1490	D-aminoacyl-tRNA deacylase activity
G7079_00315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7079_00320	COG0438	transferase activity, transferring glycosyl groups
G7079_00335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7079_00335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7079_00345	COG0242	peptide deformylase activity
G7079_00350	COG1652	LysM domain
G7079_00360	COG2922	Belongs to the Smg family
G7079_00365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G7079_00365	COG1754	DNA topoisomerase type I activity
G7079_00370	COG1764	response to oxidative stress
G7079_00375	COG0009	L-threonylcarbamoyladenylate synthase
G7079_00390	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_00400	COG2755	lipolytic protein G-D-S-L family
G7079_00405	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_00415	COG1609	Transcriptional regulator
G7079_00435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G7079_00450	COG2272	Belongs to the type-B carboxylesterase lipase family
G7079_00465	COG0616	signal peptide processing
G7079_00470	COG0534	Mate efflux family protein
G7079_00490	COG4585	Histidine kinase
G7079_00510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G7079_00525	COG1902	pentaerythritol trinitrate reductase activity
G7079_00550	COG2860	membrane
G7079_00570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G7079_00580	COG2177	Part of the ABC transporter FtsEX involved in
G7079_00585	COG2884	Cell division ATP-binding protein ftsE
G7079_00590	COG0513	Belongs to the DEAD box helicase family
G7079_00595	COG3118	belongs to the thioredoxin family
G7079_00600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G7079_00620	COG3100	YcgL domain-containing protein
G7079_00625	COG1294	oxidase, subunit
G7079_00630	COG1271	oxidase subunit
G7079_00640	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
G7079_00645	COG0183	Belongs to the thiolase family
G7079_00665	COG0515	serine threonine protein kinase
G7079_00685	COG2032	superoxide dismutase activity
G7079_00690	COG2204	response regulator
G7079_00695	COG3852	Histidine kinase
G7079_00735	COG1376	ErfK ybiS ycfS ynhG family protein
G7079_00745	COG3023	N-Acetylmuramoyl-L-alanine amidase
G7079_00750	COG0070	glutamate synthase
G7079_00750	COG0067	glutamate synthase
G7079_00750	COG0069	glutamate synthase activity
G7079_00755	COG0493	'glutamate synthase
G7079_00770	COG0667	Aldo Keto reductase
G7079_00775	COG0656	L-ascorbic acid biosynthetic process
G7079_00785	COG0667	Aldo Keto reductase
G7079_00805	COG0789	Transcriptional regulator
G7079_00820	COG0004	ammonium transporteR
G7079_00825	COG0347	Belongs to the P(II) protein family
G7079_00835	COG0174	glutamine synthetase
G7079_00840	COG1968	undecaprenyl-diphosphatase activity
G7079_00855	COG2267	carboxylic ester hydrolase activity
G7079_00875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7079_00890	COG4999	Histidine kinase
G7079_00890	COG3850	Histidine kinase
G7079_00890	COG3437	response regulator, receiver
G7079_00890	COG2205	protein histidine kinase activity
G7079_00930	COG0302	gtp cyclohydrolase
G7079_00975	COG1451	nucleotide metabolic process
G7079_00980	COG3122	Protein conserved in bacteria
G7079_00995	COG0640	Transcriptional regulator
G7079_01025	COG1074	ATP-dependent DNA helicase activity
G7079_01030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G7079_01035	COG1127	ABC transporter
G7079_01040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7079_01045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G7079_01060	COG2853	Lipoprotein
G7079_01075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7079_01080	COG0861	Integral membrane protein TerC family
G7079_01090	COG3647	Membrane
G7079_01095	COG1752	Esterase of the alpha-beta hydrolase superfamily
G7079_01100	COG3186	Phenylalanine-4-hydroxylase
G7079_01105	COG4772	TonB-dependent receptor
G7079_01115	COG4585	Histidine kinase
G7079_01140	COG0784	Response regulator, receiver
G7079_01150	COG0471	metal ion transport
G7079_01150	COG3273	potassium ion transport
G7079_01155	COG1741	Belongs to the pirin family
G7079_01165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7079_01215	COG0187	DNA topoisomerase II activity
G7079_01220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G7079_01240	COG0594	ribonuclease P activity
G7079_01245	COG0706	membrane insertase activity
G7079_01265	COG4555	ABC transporter
G7079_01295	COG1131	(ABC) transporter
G7079_01300	COG0842	Transport permease protein
G7079_01305	COG0084	hydrolase, TatD family'
G7079_01310	COG1643	Atp-dependent helicase
G7079_01325	COG1187	pseudouridine synthase activity
G7079_01345	COG1652	LysM domain
G7079_01350	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7079_01350	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7079_01355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G7079_01360	COG2945	thiolester hydrolase activity
G7079_01370	COG3468	outer membrane autotransporter barrel domain protein
G7079_01410	COG1040	competence protein
G7079_01415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G7079_01420	COG0156	8-amino-7-oxononanoate synthase activity
G7079_01435	COG0697	spore germination
G7079_01475	COG0729	surface antigen
G7079_01490	COG0519	Catalyzes the synthesis of GMP from XMP
G7079_01490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7079_01525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G7079_01555	COG0037	tRNA processing
G7079_01565	COG2937	Belongs to the GPAT DAPAT family
G7079_01575	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
G7079_01580	COG0210	DNA helicase
G7079_01590	COG0515	serine threonine protein kinase
G7079_01590	COG2815	serine threonine protein kinase
G7079_01600	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G7079_01615	COG2826	transposase and inactivated derivatives, IS30 family
G7079_01620	COG3590	peptidase
G7079_01625	COG0477	Major facilitator Superfamily
G7079_01650	COG1538	Outer membrane efflux protein
G7079_01655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7079_01670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G7079_01675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G7079_01690	COG0463	Glycosyl transferase, family 2
G7079_01695	COG1475	DNA binding
G7079_01700	COG1192	Involved in chromosome partitioning
G7079_01705	COG0357	Ribosomal RNA small subunit methyltransferase G
G7079_01710	COG2091	lysine biosynthetic process via aminoadipic acid
G7079_01730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G7079_01755	COG0463	Glycosyl transferase, family 2
G7079_01760	COG1506	peptidase
G7079_01760	COG0823	Involved in the tonB-independent uptake of proteins
G7079_01765	COG0625	glutathione transferase activity
G7079_01775	COG0210	DNA helicase
G7079_01780	COG4807	Protein conserved in bacteria
G7079_01800	COG1132	(ABC) transporter
G7079_01810	COG2323	membrane
G7079_01815	COG0408	coproporphyrinogen oxidase activity
G7079_01845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7079_01850	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G7079_01855	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G7079_01870	COG2205	protein histidine kinase activity
G7079_01875	COG0745	RESPONSE REGULATOR receiver
G7079_01880	COG1368	sulfuric ester hydrolase activity
G7079_01895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G7079_01905	COG0612	Peptidase, M16
G7079_01920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7079_01925	COG0596	Alpha beta hydrolase
G7079_01935	COG0727	PFAM Uncharacterised protein family (UPF0153)
G7079_01940	COG0318	PFAM AMP-dependent synthetase and ligase
G7079_01945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7079_01960	COG1064	alcohol dehydrogenase
G7079_01965	COG0612	Peptidase, M16
G7079_01970	COG0564	pseudouridine synthase activity
G7079_01995	COG1216	Glycosyl transferase, family 2
G7079_02035	COG0583	DNA-binding transcription factor activity
G7079_02040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G7079_02045	COG2224	Isocitrate lyase
G7079_02050	COG3706	GGDEF domain
G7079_02070	COG0606	chelatase, subunit chli
G7079_02095	COG1166	arginine decarboxylase activity
G7079_02105	COG4221	oxidoreductase activity
G7079_02140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7079_02160	COG2807	transmembrane transport
G7079_02170	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G7079_02175	COG0739	heme binding
G7079_02185	COG0187	DNA topoisomerase II activity
G7079_02270	COG0776	regulation of translation
G7079_02290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G7079_02295	COG4942	peptidase
G7079_02300	COG0793	Belongs to the peptidase S41A family
G7079_02320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G7079_02325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G7079_02335	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G7079_02360	COG1612	heme a metabolic process
G7079_02365	COG0109	protoheme IX farnesyltransferase activity
G7079_02370	COG3145	DNA-N1-methyladenine dioxygenase activity
G7079_02375	COG2169	Transcriptional regulator
G7079_02375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G7079_02380	COG0823	Involved in the tonB-independent uptake of proteins
G7079_02380	COG4946	Tricorn protease homolog
G7079_02380	COG1506	peptidase
G7079_02385	COG0358	DNA primase activity
G7079_02405	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G7079_02410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G7079_02415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G7079_02440	COG0617	tRNA 3'-terminal CCA addition
G7079_02445	COG0741	lytic transglycosylase activity
G7079_02450	COG0730	response to heat
G7079_02470	COG2863	cytochrome
G7079_02480	COG0366	Alpha amylase catalytic
G7079_02485	COG3572	ergothioneine biosynthetic process
G7079_02495	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G7079_02515	COG1307	EDD domain protein, DegV family
G7079_02525	COG0804	urea catabolic process
G7079_02545	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G7079_02560	COG0436	Aminotransferase
G7079_02565	COG1162	GTPase activity
G7079_02575	COG0280	phosphate acetyltransferase
G7079_02575	COG0281	malic enzyme
G7079_02605	COG2818	Glycosylase
G7079_02615	COG2814	Major facilitator Superfamily
G7079_02635	COG2972	Histidine kinase
G7079_02650	COG3795	YCII-related domain
G7079_02655	COG3795	YCII-related domain
G7079_02670	COG4941	Belongs to the sigma-70 factor family
G7079_02700	COG2813	Specifically methylates the guanine in position
G7079_02705	COG1187	pseudouridine synthase activity
G7079_02710	COG2885	chlorophyll binding
G7079_02710	COG3047	cAMP biosynthetic process
G7079_02720	COG1666	GTP binding
G7079_02725	COG0697	spore germination
G7079_02745	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7079_02750	COG3264	Mechanosensitive ion channel
G7079_02750	COG1196	nuclear chromosome segregation
G7079_02755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7079_02765	COG0356	it plays a direct role in the translocation of protons across the membrane
G7079_02775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G7079_02795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G7079_02800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G7079_02815	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G7079_02820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G7079_02900	COG0577	efflux transmembrane transporter activity
G7079_02900	COG1136	(ABC) transporter
G7079_02990	COG4206	TonB-dependent receptor
G7079_03000	COG1956	GAF domain-containing protein
G7079_03010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G7079_03015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7079_03020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7079_03040	COG0720	synthase
G7079_03095	COG1002	Type II restriction enzyme, methylase subunits
G7079_03105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G7079_03115	COG1278	Cold shock
G7079_03120	COG0564	pseudouridine synthase activity
G7079_03125	COG3654	unkown
G7079_03140	COG3384	dioxygenase
G7079_03150	COG4181	ATPase activity
G7079_03160	COG0151	Belongs to the GarS family
G7079_03170	COG0138	bifunctional purine biosynthesis protein purh
G7079_03175	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G7079_03185	COG2264	protein methyltransferase activity
G7079_03195	COG0439	Biotin carboxylase
G7079_03200	COG0511	ligase activity, forming carbon-carbon bonds
G7079_03205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G7079_03210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7079_03215	COG4232	protein-disulfide reductase activity
G7079_03220	COG1324	tolerance protein
G7079_03245	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G7079_03255	COG0778	Nitroreductase
G7079_03260	COG2353	YceI-like domain
G7079_03265	COG1741	Belongs to the pirin family
G7079_03290	COG1560	Kdo2-lipid A biosynthetic process
G7079_03295	COG1519	Transferase
G7079_03300	COG1538	Outer membrane efflux protein
G7079_03305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G7079_03310	COG1309	transcriptional regulator
G7079_03325	COG0473	3-isopropylmalate dehydrogenase activity
G7079_03340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7079_03365	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G7079_03375	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G7079_03390	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G7079_03395	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G7079_03405	COG1872	DUF167
G7079_03425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7079_03435	COG0671	phosphoesterase, PA-phosphatase related
G7079_03440	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_03445	COG1595	DNA-templated transcription, initiation
G7079_03460	COG0346	lactoylglutathione lyase activity
G7079_03465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G7079_03475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7079_03480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G7079_03490	COG1773	rubredoxin
G7079_03525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7079_03545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G7079_03575	COG0006	proline dipeptidase activity
G7079_03580	COG0006	proline dipeptidase activity
G7079_03595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G7079_03600	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G7079_03605	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G7079_03610	COG1561	YicC-like family, N-terminal region
G7079_03625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7079_03635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G7079_03650	COG0372	Belongs to the citrate synthase family
G7079_03665	COG0745	RESPONSE REGULATOR receiver
G7079_03670	COG2205	protein histidine kinase activity
G7079_03680	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G7079_03710	COG0714	Associated with various cellular activities
G7079_03740	COG1301	dicarboxylic acid transport
G7079_03745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G7079_03750	COG0427	acetyl-CoA hydrolase
G7079_03755	COG3682	Transcriptional regulator
G7079_03795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G7079_03805	COG4251	negative regulation of phosphorylation
G7079_03805	COG3706	GGDEF domain
G7079_03805	COG5001	Diguanylate cyclase
G7079_03805	COG2203	Gaf domain
G7079_03825	COG0469	pyruvate kinase activity
G7079_03830	COG3588	fructose-bisphosphate aldolase
G7079_03845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7079_03860	COG1970	mechanosensitive ion channel activity
G7079_03880	COG3273	potassium ion transport
G7079_03880	COG0471	metal ion transport
G7079_03890	COG2022	thiamine diphosphate biosynthetic process
G7079_03910	COG0189	ligase activity
G7079_03910	COG4067	protein conserved in archaea
G7079_03915	COG0189	ligase activity
G7079_03920	COG0745	RESPONSE REGULATOR receiver
G7079_03925	COG0642	Histidine kinase
G7079_03930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G7079_03940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G7079_03945	COG3706	GGDEF domain
G7079_03945	COG4251	negative regulation of phosphorylation
G7079_03945	COG5001	Diguanylate cyclase
G7079_03945	COG2203	Gaf domain
G7079_03950	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G7079_03970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G7079_03975	COG3422	double-strand break repair
G7079_03980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7079_03985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G7079_03995	COG2119	membrane
G7079_04000	COG0667	Aldo Keto reductase
G7079_04020	COG1595	DNA-templated transcription, initiation
G7079_04025	COG0330	HflC and HflK could
G7079_04040	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G7079_04045	COG0509	glycine decarboxylation via glycine cleavage system
G7079_04065	COG1704	LemA family
G7079_04070	COG0501	Belongs to the peptidase M48B family
G7079_04105	COG3759	membrane
G7079_04115	COG1960	acyl-CoA dehydrogenase activity
G7079_04125	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G7079_04165	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G7079_04170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7079_04175	COG0463	Glycosyl transferase, family 2
G7079_04180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G7079_04180	COG0617	tRNA 3'-terminal CCA addition
G7079_04180	COG3620	sequence-specific DNA binding
G7079_04185	COG1272	protein, Hemolysin III
G7079_04190	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G7079_04200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G7079_04205	COG0626	cystathionine gamma-synthase activity
G7079_04210	COG0527	aspartate kinase activity
G7079_04210	COG0460	homoserine dehydrogenase
G7079_04215	COG5001	Diguanylate cyclase
G7079_04215	COG5002	protein histidine kinase activity
G7079_04220	COG1760	l-serine dehydratase
G7079_04235	COG3038	cytochrome b561
G7079_04240	COG2353	YceI-like domain
G7079_04250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G7079_04275	COG0259	pyridoxamine-phosphate oxidase activity
G7079_04280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G7079_04315	COG1678	Uncharacterized ACR, COG1678
G7079_04320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G7079_04330	COG2239	Acts as a magnesium transporter
G7079_04335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G7079_04340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7079_04350	COG1660	Displays ATPase and GTPase activities
G7079_04370	COG1137	ATPase activity
G7079_04385	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G7079_04395	COG0271	Belongs to the BolA IbaG family
G7079_04415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G7079_04420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G7079_04430	COG0628	permease
G7079_04440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G7079_04445	COG3178	'Phosphotransferase
G7079_04460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G7079_04460	COG1648	precorrin-2 dehydrogenase activity
G7079_04465	COG0583	DNA-binding transcription factor activity
G7079_04470	COG0175	sulfate reduction
G7079_04475	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7079_04480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G7079_04485	COG2261	transglycosylase associated protein
G7079_04510	COG4774	siderophore transport
G7079_04515	COG2146	nitrite reductase [NAD(P)H] activity
G7079_04520	COG0456	acetyltransferase
G7079_04525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G7079_04530	COG0719	Fe-S assembly protein
G7079_04535	COG0396	ATPase activity
G7079_04540	COG0719	Fe-S assembly protein
G7079_04545	COG1959	2 iron, 2 sulfur cluster binding
G7079_04580	COG0739	heme binding
G7079_04590	COG1764	response to oxidative stress
G7079_04600	COG0384	phenazine biosynthesis protein PhzF
G7079_04610	COG0527	aspartate kinase activity
G7079_04620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G7079_04630	COG0142	geranyltranstransferase activity
G7079_04675	COG1073	alpha beta
G7079_04710	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G7079_04725	COG1946	Acyl-CoA thioesterase
G7079_04740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7079_04740	COG0116	Belongs to the methyltransferase superfamily
G7079_04745	COG3963	phosphatidate phosphatase activity
G7079_04750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7079_04765	COG1960	acyl-CoA dehydrogenase activity
G7079_04790	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G7079_04795	COG1194	a g-specific adenine glycosylase
G7079_04805	COG0552	protein localization to endoplasmic reticulum
G7079_04810	COG0742	ribosomal rna small subunit methyltransferase
G7079_04825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7079_04835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7079_04840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G7079_04855	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G7079_04860	COG0343	queuine tRNA-ribosyltransferase activity
G7079_04865	COG1862	Preprotein translocase
G7079_04870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7079_04875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7079_04905	COG1253	flavin adenine dinucleotide binding
G7079_04915	COG0306	phosphate transporter
G7079_04940	COG3104	oligopeptide transport
G7079_04945	COG1297	OPT oligopeptide transporter protein
G7079_04950	COG0823	Involved in the tonB-independent uptake of proteins
G7079_04950	COG1506	peptidase
G7079_04970	COG4535	Mg2 and Co2 transporter CorC
G7079_04975	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G7079_04980	COG1702	phosphate starvation-inducible protein PhoH
G7079_04985	COG1309	transcriptional regulator
G7079_04995	COG1131	(ABC) transporter
G7079_05000	COG0842	Transport permease protein
G7079_05015	COG0741	lytic transglycosylase activity
G7079_05020	COG0723	plastoquinol--plastocyanin reductase activity
G7079_05025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G7079_05030	COG2857	Cytochrome c1
G7079_05035	COG0625	glutathione transferase activity
G7079_05040	COG2969	positive regulation of protein catabolic process
G7079_05060	COG2835	tetraacyldisaccharide 4'-kinase activity
G7079_05085	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G7079_05095	COG2095	MarC family integral membrane protein
G7079_05105	COG1611	Belongs to the LOG family
G7079_05110	COG3275	phosphorelay sensor kinase activity
G7079_05115	COG4969	Belongs to the N-Me-Phe pilin family
G7079_05180	COG2207	Transcriptional regulator
G7079_05190	COG1741	Belongs to the pirin family
G7079_05200	COG0243	molybdopterin cofactor binding
G7079_05205	COG3781	membrane
G7079_05220	COG2837	iron assimilation
G7079_05225	COG0484	heat shock protein binding
G7079_05250	COG2826	transposase and inactivated derivatives, IS30 family
G7079_05295	COG2826	transposase and inactivated derivatives, IS30 family
G7079_05325	COG0582	viral genome integration into host DNA
G7079_05340	COG0556	nucleotide-excision repair
G7079_05345	COG1652	LysM domain
G7079_05375	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G7079_05385	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G7079_05390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G7079_05420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G7079_05425	COG3590	peptidase
G7079_05435	COG0612	Peptidase, M16
G7079_05440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G7079_05460	COG0513	Belongs to the DEAD box helicase family
G7079_05465	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G7079_05485	COG3118	belongs to the thioredoxin family
G7079_05525	COG0495	leucyl-tRNA aminoacylation
G7079_05540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G7079_05560	COG2968	Membrane
G7079_05565	COG0424	maF-like protein
G7079_05570	COG1530	ribonuclease E activity
G7079_05580	COG0312	modulator of DNA gyrase
G7079_05590	COG0312	modulator of DNA gyrase
G7079_05605	COG0142	geranyltranstransferase activity
G7079_05615	COG0037	tRNA processing
G7079_05640	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7079_05645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7079_05650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G7079_05655	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7079_05665	COG0750	zinc metalloprotease
G7079_05670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G7079_05675	COG0575	Belongs to the CDS family
G7079_05680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G7079_05705	COG0052	Belongs to the universal ribosomal protein uS2 family
G7079_05710	COG0024	Methionine aminopeptidase
G7079_05725	COG1393	Belongs to the ArsC family
G7079_05730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7079_05735	COG0367	asparagine synthase
G7079_05740	COG0500	methyltransferase
G7079_05785	COG2010	Cytochrome c
G7079_05800	COG3278	Belongs to the heme-copper respiratory oxidase family
G7079_05835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G7079_05885	COG4772	TonB-dependent receptor
G7079_05895	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G7079_05910	COG0288	reversible hydration of carbon dioxide
G7079_05925	COG0277	FAD linked oxidase domain protein
G7079_05930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7079_05935	COG2181	nitrate reductase activity
G7079_05940	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G7079_05945	COG1140	nitrate reductase beta subunit
G7079_05950	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G7079_05960	COG0314	molybdopterin synthase activity
G7079_05970	COG0303	'Molybdopterin
G7079_05975	COG0315	cyclic pyranopterin monophosphate synthase activity
G7079_05975	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7079_05980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G7079_05995	COG0557	exoribonuclease II activity
G7079_06000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7079_06015	COG3220	belongs to the UPF0276 family
G7079_06025	COG0704	Plays a role in the regulation of phosphate uptake
G7079_06035	COG0581	inorganic phosphate transmembrane transporter activity
G7079_06040	COG0573	inorganic phosphate transmembrane transporter activity
G7079_06045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G7079_06060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G7079_06070	COG1024	Enoyl-CoA hydratase
G7079_06105	COG0824	Thioesterase
G7079_06110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G7079_06120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G7079_06125	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7079_06140	COG0196	riboflavin kinase activity
G7079_06155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G7079_06185	COG2814	Major facilitator Superfamily
G7079_06190	COG1566	PFAM secretion protein HlyD family protein
G7079_06195	COG1538	Outer membrane efflux protein
G7079_06200	COG1846	Transcriptional regulator
G7079_06210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G7079_06215	COG0228	four-way junction DNA binding
G7079_06220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G7079_06225	COG0336	Belongs to the RNA methyltransferase TrmD family
G7079_06245	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G7079_06255	COG2378	regulation of single-species biofilm formation
G7079_06275	COG4771	TonB-dependent receptor
G7079_06280	COG1546	Belongs to the CinA family
G7079_06285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G7079_06290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G7079_06295	COG2137	regulation of response to DNA damage stimulus
G7079_06300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G7079_06305	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G7079_06335	COG0366	Alpha amylase catalytic
G7079_06345	COG1082	Xylose isomerase domain protein TIM barrel
G7079_06350	COG2382	esterase
G7079_06360	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G7079_06365	COG0800	Aldolase
G7079_06370	COG0837	glucose binding
G7079_06385	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G7079_06405	COG0351	phosphomethylpyrimidine kinase
G7079_06405	COG0352	thiamine-phosphate diphosphorylase activity
G7079_06415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G7079_06420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7079_06430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G7079_06440	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G7079_06450	COG0617	tRNA 3'-terminal CCA addition
G7079_06460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G7079_06465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G7079_06470	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G7079_06475	COG0166	Belongs to the GPI family
G7079_06480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G7079_06485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G7079_06485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G7079_06490	COG0802	atpase or kinase
G7079_06495	COG0860	N-Acetylmuramoyl-L-alanine amidase
G7079_06500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G7079_06515	COG2878	Part of a membrane complex involved in electron transport
G7079_06520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7079_06520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7079_06535	COG0489	protein tyrosine kinase activity
G7079_06540	COG0717	Belongs to the dCTP deaminase family
G7079_06585	COG0412	Dienelactone hydrolase
G7079_06590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G7079_06595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7079_06600	COG3015	lipoprotein NlpE involved in copper resistance
G7079_06605	COG0433	COG0433 Predicted ATPase
G7079_06615	COG0688	phosphatidylethanolamine metabolic process
G7079_06620	COG1999	signal sequence binding
G7079_06625	COG2890	protein-(glutamine-N5) methyltransferase activity
G7079_06635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G7079_06645	COG0101	tRNA pseudouridine synthase activity
G7079_06655	COG0133	tryptophan synthase activity
G7079_06670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G7079_06675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7079_06690	COG0149	triose-phosphate isomerase activity
G7079_06730	COG0625	glutathione transferase activity
G7079_06735	COG3104	oligopeptide transport
G7079_06750	COG1187	pseudouridine synthase activity
G7079_06765	COG1201	RNA secondary structure unwinding
G7079_06770	COG0339	signal peptide processing
G7079_06775	COG0386	Belongs to the glutathione peroxidase family
G7079_06800	COG2133	pyrroloquinoline quinone binding
G7079_06830	COG4104	PAAR repeat-containing protein
G7079_06840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G7079_06845	COG0084	hydrolase, TatD family'
G7079_06860	COG1960	acyl-CoA dehydrogenase activity
G7079_06865	COG0625	glutathione transferase activity
G7079_06870	COG0022	dehydrogenase e1 component
G7079_06880	COG0354	folic acid binding
G7079_06895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G7079_06920	COG4591	ABC-type transport system involved in lipoprotein release permease component
G7079_06935	COG0811	peptide transport
G7079_06945	COG1132	(ABC) transporter
G7079_06950	COG1663	tetraacyldisaccharide 4'-kinase activity
G7079_06960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G7079_06965	COG0322	excinuclease ABC activity
G7079_06970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G7079_06990	COG0069	glutamate synthase activity
G7079_07000	COG0529	Catalyzes the synthesis of activated sulfate
G7079_07000	COG2895	sulfate adenylyltransferase (ATP) activity
G7079_07015	COG0489	protein tyrosine kinase activity
G7079_07020	COG0484	heat shock protein binding
G7079_07045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G7079_07050	COG2244	polysaccharide biosynthetic process
G7079_07070	COG0438	transferase activity, transferring glycosyl groups
G7079_07080	COG0438	transferase activity, transferring glycosyl groups
G7079_07085	COG0438	transferase activity, transferring glycosyl groups
G7079_07095	COG1086	Polysaccharide biosynthesis protein
G7079_07100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7079_07130	COG0535	radical SAM domain protein
G7079_07165	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G7079_07190	COG1132	(ABC) transporter
G7079_07195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7079_07220	COG4221	oxidoreductase activity
G7079_07255	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G7079_07260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G7079_07270	COG0077	Prephenate dehydratase
G7079_07270	COG1605	Chorismate mutase
G7079_07275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G7079_07280	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G7079_07310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7079_07335	COG1595	DNA-templated transcription, initiation
G7079_07350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G7079_07370	COG2197	response regulator
G7079_07375	COG1530	ribonuclease E activity
G7079_07390	COG2154	pterin-4-alpha-carbinolamine dehydratase
G7079_07395	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G7079_07395	COG0316	Belongs to the HesB IscA family
G7079_07425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7079_07455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7079_07460	COG2957	Belongs to the agmatine deiminase family
G7079_07470	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G7079_07475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G7079_07485	COG0776	regulation of translation
G7079_07495	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G7079_07510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G7079_07515	COG0183	Belongs to the thiolase family
G7079_07520	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7079_07520	COG1024	Enoyl-CoA hydratase
G7079_07530	COG0105	UTP biosynthetic process
G7079_07535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G7079_07545	COG1426	Protein conserved in bacteria
G7079_07555	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7079_07560	COG1160	GTP binding
G7079_07565	COG0746	molybdenum cofactor guanylyltransferase activity
G7079_07570	COG0303	'Molybdopterin
G7079_07575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G7079_07595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G7079_07605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7079_07605	COG0519	Catalyzes the synthesis of GMP from XMP
G7079_07610	COG1309	transcriptional regulator
G7079_07615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7079_07645	COG3706	GGDEF domain
G7079_07650	COG0668	transmembrane transport
G7079_07665	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G7079_07710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G7079_07715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G7079_07730	COG1674	ftsk spoiiie
G7079_07735	COG0492	ferredoxin-NADP+ reductase activity
G7079_07745	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G7079_07755	COG0542	response to heat
G7079_07760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G7079_07770	COG0482	sulfurtransferase activity
G7079_07775	COG2915	High frequency lysogenization protein hflD homolog
G7079_07780	COG2409	Drug exporters of the RND superfamily
G7079_07785	COG2826	transposase and inactivated derivatives, IS30 family
G7079_07805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G7079_07820	COG1024	Enoyl-CoA hydratase
G7079_07825	COG0784	Response regulator, receiver
G7079_07825	COG2198	Histidine kinase
G7079_07825	COG2205	protein histidine kinase activity
G7079_07850	COG4676	Protein conserved in bacteria
G7079_07855	COG3279	Response regulator of the LytR AlgR family
G7079_07865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G7079_07875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7079_07880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G7079_07885	COG0505	Belongs to the CarA family
G7079_07890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G7079_07905	COG0443	Heat shock 70 kDa protein
G7079_07910	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7079_07915	COG1420	regulation of RNA biosynthetic process
G7079_07925	COG0735	belongs to the Fur family
G7079_07930	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7079_07935	COG2914	Belongs to the UPF0125 (RnfH) family
G7079_07940	COG2867	negative regulation of translational initiation
G7079_07950	COG2205	protein histidine kinase activity
G7079_07950	COG2202	Pas domain
G7079_07980	COG0305	Participates in initiation and elongation during chromosome replication
G7079_07990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G7079_07995	COG0360	Binds together with S18 to 16S ribosomal RNA
G7079_08005	COG0017	Asparaginyl-tRNA synthetase
G7079_08020	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_08030	COG0288	reversible hydration of carbon dioxide
G7079_08055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7079_08060	COG2925	Exonuclease
G7079_08080	COG2902	Dehydrogenase
G7079_08085	COG1960	acyl-CoA dehydrogenase activity
G7079_08100	COG0646	methionine synthase
G7079_08100	COG1410	methionine synthase
G7079_08105	COG2814	Major facilitator Superfamily
G7079_08115	COG2900	Belongs to the SlyX family
G7079_08135	COG0386	Belongs to the glutathione peroxidase family
G7079_08145	COG1725	Transcriptional regulator
G7079_08150	COG1131	(ABC) transporter
G7079_08190	COG2850	peptidyl-arginine hydroxylation
G7079_08195	COG2153	protein acetylation
G7079_08200	COG0567	Dehydrogenase, E1 component
G7079_08215	COG0387	Pfam Sodium calcium exchanger
G7079_08225	COG0604	alcohol dehydrogenase
G7079_08240	COG0678	peroxiredoxin activity
G7079_08265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G7079_08270	COG3115	cell septum assembly
G7079_08285	COG2350	Protein conserved in bacteria
G7079_08300	COG1187	pseudouridine synthase activity
G7079_08335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7079_08340	COG0436	Aminotransferase
G7079_08345	COG4133	protoheme IX ABC transporter activity
G7079_08355	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
G7079_08385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7079_08410	COG3088	subunit of a heme lyase
G7079_08410	COG4235	cytochrome complex assembly
G7079_08420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G7079_08440	COG3243	poly(R)-hydroxyalkanoic acid synthase
G7079_08450	COG1183	phosphatidylcholine synthase activity
G7079_08460	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_08470	COG2205	protein histidine kinase activity
G7079_08470	COG0784	Response regulator, receiver
G7079_08480	COG2610	gluconate transmembrane transporter activity
G7079_08490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7079_08500	COG0477	Major facilitator Superfamily
G7079_08505	COG2183	response to ionizing radiation
G7079_08510	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7079_08510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7079_08525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7079_08535	COG1185	polyribonucleotide nucleotidyltransferase activity
G7079_08540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G7079_08560	COG0195	Participates in both transcription termination and antitermination
G7079_08565	COG0779	Required for maturation of 30S ribosomal subunits
G7079_08575	COG1007	ATP synthesis coupled electron transport
G7079_08605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G7079_08610	COG1034	ATP synthesis coupled electron transport
G7079_08620	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
G7079_08625	COG0649	NAD binding
G7079_08635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7079_08640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7079_08650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G7079_08665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7079_08665	COG0519	Catalyzes the synthesis of GMP from XMP
G7079_08670	COG2081	HI0933 family
G7079_08710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G7079_08715	COG3706	GGDEF domain
G7079_08720	COG2203	Gaf domain
G7079_08720	COG2199	diguanylate cyclase activity
G7079_08765	COG0251	oxidation-reduction process
G7079_08780	COG3038	cytochrome b561
G7079_08800	COG0204	Acyl-transferase
G7079_08805	COG3706	GGDEF domain
G7079_08815	COG3706	GGDEF domain
G7079_08820	COG1619	proteins homologs of microcin C7 resistance protein MccF
G7079_08830	COG2203	Gaf domain
G7079_08830	COG4251	negative regulation of phosphorylation
G7079_08830	COG5001	Diguanylate cyclase
G7079_08830	COG3706	GGDEF domain
G7079_08855	COG0625	glutathione transferase activity
G7079_08865	COG1901	pseudouridine methyltransferase
G7079_08895	COG3220	belongs to the UPF0276 family
G7079_08925	COG2944	sequence-specific DNA binding
G7079_08935	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7079_08935	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7079_08935	COG1703	isobutyryl-CoA mutase activity
G7079_08940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7079_08960	COG1960	acyl-CoA dehydrogenase activity
G7079_08970	COG0183	Belongs to the thiolase family
G7079_08985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7079_09020	COG1024	Enoyl-CoA hydratase
G7079_09025	COG2957	Belongs to the agmatine deiminase family
G7079_09065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G7079_09075	COG0277	FAD linked oxidase domain protein
G7079_09080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7079_09090	COG0531	amino acid
G7079_09095	COG0235	Class ii aldolase
G7079_09100	COG0235	Class ii aldolase
G7079_09110	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
G7079_09120	COG3300	MHYT domain
G7079_09120	COG5001	Diguanylate cyclase
G7079_09125	COG2986	histidine ammonia-lyase
G7079_09130	COG0124	histidyl-tRNA synthetase
G7079_09140	COG0784	Response regulator, receiver
G7079_09140	COG5002	protein histidine kinase activity
G7079_09140	COG2198	Histidine kinase
G7079_09145	COG4797	methyltransferase
G7079_09145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7079_09235	COG3501	Rhs element vgr protein
G7079_09260	COG2885	chlorophyll binding
G7079_09270	COG3210	domain, Protein
G7079_09285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G7079_09290	COG0165	Argininosuccinate lyase
G7079_09295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G7079_09300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7079_09305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7079_09310	COG0137	argininosuccinate synthase activity
G7079_09315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G7079_09350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G7079_09360	COG1469	GTP cyclohydrolase I activity
G7079_09380	COG0402	S-adenosylhomocysteine deaminase activity
G7079_09390	COG1509	lysine 2,3-aminomutase activity
G7079_09395	COG5001	Diguanylate cyclase
G7079_09410	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_09415	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
G7079_09420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G7079_09420	COG0140	phosphoribosyl-ATP diphosphatase activity
G7079_09425	COG0107	imidazoleglycerol-phosphate synthase activity
G7079_09430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G7079_09440	COG0131	Imidazoleglycerol-phosphate dehydratase
G7079_09440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G7079_09445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G7079_09450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G7079_09455	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G7079_09485	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
G7079_09500	COG4948	Mandelate Racemase Muconate Lactonizing
G7079_09510	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G7079_09515	COG0527	aspartate kinase activity
G7079_09515	COG0460	homoserine dehydrogenase
G7079_09540	COG1012	belongs to the aldehyde dehydrogenase family
G7079_09555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G7079_09560	COG0697	spore germination
G7079_09565	COG0671	phosphoesterase, PA-phosphatase related
G7079_09570	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G7079_09580	COG1012	belongs to the aldehyde dehydrogenase family
G7079_09585	COG5001	Diguanylate cyclase
G7079_09590	COG1595	DNA-templated transcription, initiation
G7079_09600	COG1132	(ABC) transporter
G7079_09605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7079_09615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7079_09620	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G7079_09630	COG1472	Belongs to the glycosyl hydrolase 3 family
G7079_09635	COG2954	triphosphatase activity
G7079_09640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7079_09660	COG1381	Involved in DNA repair and RecF pathway recombination
G7079_09680	COG0681	Belongs to the peptidase S26 family
G7079_09690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7079_09705	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7079_09705	COG1024	Enoyl-CoA hydratase
G7079_09720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G7079_09725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G7079_09730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G7079_09735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G7079_09740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7079_09750	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_09755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G7079_09760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7079_09765	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G7079_09770	COG1399	metal-binding, possibly nucleic acid-binding protein
G7079_09790	COG0714	Associated with various cellular activities
G7079_09810	COG0537	adenosine 5'-monophosphoramidase activity
G7079_09820	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G7079_09825	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G7079_09860	COG0314	molybdopterin synthase activity
G7079_09885	COG3642	lipopolysaccharide core region biosynthetic process
G7079_09890	COG0859	PFAM glycosyl transferase family 9
G7079_09910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G7079_09965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G7079_09970	COG0740	serine-type endopeptidase activity
G7079_09975	COG0544	peptidyl-prolyl cis-trans isomerase activity
G7079_10015	COG0473	3-isopropylmalate dehydrogenase activity
G7079_10030	COG4783	chaperone-mediated protein folding
G7079_10035	COG0745	RESPONSE REGULATOR receiver
G7079_10045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G7079_10070	COG1131	(ABC) transporter
G7079_10075	COG1725	Transcriptional regulator
G7079_10080	COG0438	transferase activity, transferring glycosyl groups
G7079_10085	COG0671	phosphoesterase, PA-phosphatase related
G7079_10105	COG4452	Inner membrane protein CreD
G7079_10110	COG2205	protein histidine kinase activity
G7079_10115	COG0745	RESPONSE REGULATOR receiver
G7079_10120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G7079_10130	COG2354	Protein conserved in bacteria
G7079_10140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G7079_10145	COG1515	deoxyribonuclease V activity
G7079_10200	COG0431	NADPH-dependent FMN reductase
G7079_10210	COG0431	NADPH-dependent FMN reductase
G7079_10355	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G7079_10365	COG2197	response regulator
G7079_10370	COG4585	Histidine kinase
G7079_10385	COG2894	cell division
G7079_10390	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G7079_10400	COG3511	phospholipase C
G7079_10415	COG0531	amino acid
G7079_10435	COG2815	serine threonine protein kinase
G7079_10435	COG0515	serine threonine protein kinase
G7079_10440	COG3850	Histidine kinase
G7079_10445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7079_10445	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7079_10455	COG0308	aminopeptidase N
G7079_10475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G7079_10485	COG0330	HflC and HflK could
G7079_10490	COG0330	HflC and HflK could
G7079_10495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G7079_10500	COG1923	regulation of RNA biosynthetic process
G7079_10505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G7079_10510	COG0531	amino acid
G7079_10525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G7079_10530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G7079_10535	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G7079_10540	COG1534	Rna-binding protein
G7079_10555	COG1238	metal cluster binding
G7079_10565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G7079_10580	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G7079_10590	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G7079_10595	COG0148	phosphopyruvate hydratase activity
G7079_10600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G7079_10635	COG0791	NLP P60 protein
G7079_10640	COG0791	NLP P60 protein
G7079_10660	COG1301	dicarboxylic acid transport
G7079_10665	COG1785	Belongs to the alkaline phosphatase family
G7079_10735	COG4771	TonB-dependent receptor
G7079_10740	COG0457	Tetratricopeptide repeat
G7079_10780	COG3070	regulator of competence-specific genes
G7079_10790	COG3409	Peptidoglycan-binding domain 1 protein
G7079_10790	COG3267	Type II secretory pathway component ExeA
G7079_10845	COG5507	3-demethylubiquinone-9 3-methyltransferase
G7079_10855	COG0513	Belongs to the DEAD box helicase family
G7079_10875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7079_10900	COG0243	molybdopterin cofactor binding
G7079_10920	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G7079_10940	COG1228	amidohydrolase
G7079_10970	COG3746	phosphate-selective porin O and P
G7079_10980	COG0735	belongs to the Fur family
G7079_10985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7079_10990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7079_11000	COG2833	Protein of unknown function (DUF455)
G7079_11015	COG0285	dihydrofolate synthase activity
G7079_11020	COG0406	alpha-ribazole phosphatase activity
G7079_11045	COG0156	8-amino-7-oxononanoate synthase activity
G7079_11065	COG1902	pentaerythritol trinitrate reductase activity
G7079_11065	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7079_11075	COG0625	glutathione transferase activity
G7079_11095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7079_11105	COG0039	L-malate dehydrogenase activity
G7079_11140	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G7079_11160	COG0154	amidase activity
G7079_11165	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G7079_11170	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G7079_11175	COG0203	ribosomal protein L17
G7079_11185	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G7079_11200	COG0201	protein transport
G7079_11210	COG1841	ribosomal large subunit assembly
G7079_11215	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G7079_11220	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G7079_11230	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G7079_11240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7079_11245	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G7079_11250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G7079_11255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G7079_11260	COG0255	Belongs to the universal ribosomal protein uL29 family
G7079_11265	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G7079_11270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G7079_11275	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G7079_11280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G7079_11285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7079_11290	COG0089	rRNA binding
G7079_11295	COG0088	Forms part of the polypeptide exit tunnel
G7079_11300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G7079_11305	COG0051	transcription antitermination factor activity, RNA binding
G7079_11310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7079_11320	COG0049	tRNA binding
G7079_11325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G7079_11330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G7079_11340	COG0222	ribosome binding
G7079_11355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G7079_11360	COG0250	Participates in transcription elongation, termination and antitermination
G7079_11365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G7079_11375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7079_11395	COG0012	GTP binding
G7079_11400	COG0193	aminoacyl-tRNA hydrolase activity
G7079_11410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G7079_11435	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G7079_11440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G7079_11445	COG0456	acetyltransferase
G7079_11450	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7079_11470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7079_11475	COG1295	ribonuclease BN
G7079_11490	COG0457	Tetratricopeptide repeat
G7079_11495	COG0252	asparaginase activity
G7079_11500	COG3227	Zinc metalloprotease (Elastase)
G7079_11555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7079_11555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7079_11585	COG3634	alkyl hydroperoxide reductase activity
G7079_11590	COG0583	DNA-binding transcription factor activity
G7079_11615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7079_11630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7079_11635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7079_11645	COG2096	Adenosyltransferase
G7079_11650	COG0123	including yeast histone deacetylase and acetoin utilization protein
G7079_11655	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G7079_11660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7079_11665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G7079_11670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7079_11680	COG2967	ApaG domain
G7079_11685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G7079_11690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7079_11705	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G7079_11715	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G7079_11720	COG1704	LemA family
G7079_11725	COG0861	Integral membrane protein TerC family
G7079_11730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G7079_11735	COG1136	(ABC) transporter
G7079_11735	COG0577	efflux transmembrane transporter activity
G7079_11740	COG0577	efflux transmembrane transporter activity
G7079_11740	COG1136	(ABC) transporter
G7079_11745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7079_11750	COG0642	Histidine kinase
G7079_11770	COG3956	TIGRFAM MazG family protein
G7079_11775	COG1218	3'(2'),5'-bisphosphate nucleotidase
G7079_11780	COG0494	nUDIX hydrolase
G7079_11790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G7079_11805	COG0643	Histidine kinase
G7079_11805	COG2198	Histidine kinase
G7079_11810	COG0840	transmembrane signaling receptor activity
G7079_11830	COG0189	ligase activity
G7079_11855	COG1199	ATP-dependent helicase activity
G7079_11860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7079_11865	COG1216	Glycosyl transferase, family 2
G7079_11865	COG0438	transferase activity, transferring glycosyl groups
G7079_11870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7079_11875	COG1643	Atp-dependent helicase
G7079_11880	COG0783	Belongs to the Dps family
G7079_11900	COG0514	ATP-dependent DNA helicase (RecQ)
G7079_11910	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G7079_11915	COG0602	queuosine metabolic process
G7079_11925	COG2885	chlorophyll binding
G7079_11950	COG0824	Thioesterase
G7079_11955	COG2255	four-way junction helicase activity
G7079_11965	COG0632	four-way junction helicase activity
G7079_11970	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G7079_12000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G7079_12005	COG3706	GGDEF domain
G7079_12020	COG0488	(ABC) transporter
G7079_12025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G7079_12025	COG4651	solute:proton antiporter activity
G7079_12030	COG0542	response to heat
G7079_12055	COG0564	pseudouridine synthase activity
G7079_12060	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7079_12070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7079_12070	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G7079_12080	COG0045	succinate-CoA ligase (ADP-forming) activity
G7079_12110	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G7079_12115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7079_12120	COG2244	polysaccharide biosynthetic process
G7079_12125	COG2226	methyltransferase
G7079_12135	COG1216	Glycosyl transferase, family 2
G7079_12150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G7079_12155	COG2226	methyltransferase
G7079_12165	COG1215	transferase activity, transferring glycosyl groups
G7079_12180	COG0438	transferase activity, transferring glycosyl groups
G7079_12185	COG0463	Glycosyl transferase, family 2
G7079_12200	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G7079_12210	COG0494	nUDIX hydrolase
G7079_12215	COG0653	protein targeting
G7079_12220	COG0739	heme binding
G7079_12230	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G7079_12245	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G7079_12250	COG1181	Belongs to the D-alanine--D-alanine ligase family
G7079_12255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7079_12275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G7079_12290	COG3116	cell division
G7079_12295	COG0275	rRNA processing
G7079_12300	COG2001	Belongs to the MraZ family
G7079_12315	COG1446	asparaginase
G7079_12330	COG0792	nuclease activity
G7079_12340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7079_12345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G7079_12360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7079_12360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7079_12365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G7079_12370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G7079_12375	COG0583	DNA-binding transcription factor activity
G7079_12385	COG0488	(ABC) transporter
G7079_12390	COG0284	orotidine-5'-phosphate decarboxylase activity
G7079_12405	COG1450	Type ii and iii secretion system protein
G7079_12420	COG3166	PFAM Fimbrial assembly family protein
G7079_12425	COG3156	type II secretion system protein K
G7079_12430	COG4795	General secretion pathway protein
G7079_12435	COG2165	general secretion pathway protein
G7079_12440	COG4970	Tfp pilus assembly protein FimT
G7079_12445	COG2165	general secretion pathway protein
G7079_12450	COG1459	type II secretion system
G7079_12455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7079_12460	COG0047	phosphoribosylformylglycinamidine synthase activity
G7079_12460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G7079_12465	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7079_12470	COG4974	Belongs to the 'phage' integrase family
G7079_12480	COG0795	lipopolysaccharide-transporting ATPase activity
G7079_12490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7079_12515	COG1183	phosphatidylcholine synthase activity
G7079_12530	COG0442	prolyl-tRNA aminoacylation
G7079_12545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7079_12550	COG1127	ABC transporter
G7079_12585	COG2086	electron transfer activity
G7079_12595	COG0463	Glycosyl transferase, family 2
G7079_12610	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_12615	COG0318	PFAM AMP-dependent synthetase and ligase
G7079_12630	COG2076	Multidrug Resistance protein
G7079_12635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G7079_12650	COG0438	transferase activity, transferring glycosyl groups
G7079_12650	COG1216	Glycosyl transferase, family 2
G7079_12670	COG0626	cystathionine gamma-synthase activity
G7079_12685	COG2885	chlorophyll binding
G7079_12695	COG0625	glutathione transferase activity
G7079_12720	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G7079_12740	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G7079_12745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7079_12765	COG0134	indole-3-glycerol-phosphate synthase activity
G7079_12770	COG2329	Antibiotic biosynthesis monooxygenase
G7079_12775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7079_12775	COG0189	ligase activity
G7079_12780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7079_12780	COG0189	ligase activity
G7079_12790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G7079_12795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7079_12810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G7079_12815	COG1597	lipid kinase activity
G7079_12830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G7079_12845	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7079_12860	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G7079_12875	COG0673	inositol 2-dehydrogenase activity
G7079_12880	COG0457	Tetratricopeptide repeat
G7079_12890	COG1501	Belongs to the glycosyl hydrolase 31 family
G7079_12895	COG2222	sugar isomerase
G7079_12900	COG1940	carbohydrate kinase activity
G7079_12910	COG1349	DNA-binding transcription factor activity
G7079_12920	COG2814	Major facilitator Superfamily
G7079_12925	COG3104	oligopeptide transport
G7079_12930	COG3483	tryptophan 2,3-dioxygenase activity
G7079_12975	COG0180	Tryptophanyl-tRNA synthetase
G7079_13015	COG4208	sulfate ABC transporter
G7079_13020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G7079_13030	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G7079_13035	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G7079_13035	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G7079_13040	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G7079_13045	COG1461	Dihydroxyacetone kinase
G7079_13055	COG3228	Belongs to the MtfA family
G7079_13060	COG2205	protein histidine kinase activity
G7079_13065	COG0745	RESPONSE REGULATOR receiver
G7079_13080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G7079_13095	COG0454	-acetyltransferase
G7079_13095	COG0456	acetyltransferase
G7079_13130	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G7079_13135	COG1522	sequence-specific DNA binding
G7079_13140	COG0686	Belongs to the AlaDH PNT family
G7079_13145	COG2267	carboxylic ester hydrolase activity
G7079_13150	COG2824	Alkylphosphonate utilization operon protein PhnA
G7079_13160	COG3189	MarR family transcriptional regulator
G7079_13165	COG0702	epimerase
G7079_13190	COG1741	Belongs to the pirin family
G7079_13225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7079_13245	COG0628	permease
G7079_13250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G7079_13255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7079_13265	COG2197	response regulator
G7079_13270	COG4585	Histidine kinase
G7079_13280	COG1131	(ABC) transporter
G7079_13285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7079_13290	COG1136	(ABC) transporter
G7079_13295	COG0577	efflux transmembrane transporter activity
G7079_13300	COG0577	efflux transmembrane transporter activity
G7079_13310	COG0697	spore germination
G7079_13315	COG1522	sequence-specific DNA binding