locus-tag	class	description
ICG51_000004	COG0590	tRNA wobble adenosine to inosine editing
ICG51_000015	COG0789	Transcriptional regulator
ICG51_000028	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICG51_000029	COG2217	Heavy metal translocating P-type atpase
ICG51_000030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ICG51_000032	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ICG51_000036	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICG51_000053	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICG51_000056	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ICG51_000059	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ICG51_000063	COG3621	Patatin-like phospholipase
ICG51_000067	COG0415	Belongs to the DNA photolyase family
ICG51_000068	COG3706	GGDEF domain
ICG51_000069	COG5001	Diguanylate cyclase
ICG51_000069	COG3300	MHYT domain
ICG51_000070	COG0702	epimerase
ICG51_000072	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_000075	COG3046	protein related to deoxyribodipyrimidine photolyase
ICG51_000080	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ICG51_000082	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICG51_000089	COG2217	Heavy metal translocating P-type atpase
ICG51_000097	COG0714	Associated with various cellular activities
ICG51_000103	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICG51_000104	COG2914	Belongs to the UPF0125 (RnfH) family
ICG51_000105	COG2867	negative regulation of translational initiation
ICG51_000106	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ICG51_000110	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ICG51_000113	COG0668	transmembrane transport
ICG51_000114	COG2199	diguanylate cyclase activity
ICG51_000115	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ICG51_000118	COG0519	Catalyzes the synthesis of GMP from XMP
ICG51_000118	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ICG51_000122	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ICG51_000123	COG0746	molybdenum cofactor guanylyltransferase activity
ICG51_000125	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICG51_000129	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ICG51_000130	COG0105	UTP biosynthetic process
ICG51_000132	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICG51_000132	COG1024	Enoyl-CoA hydratase
ICG51_000133	COG0183	Belongs to the thiolase family
ICG51_000134	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ICG51_000136	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICG51_000137	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ICG51_000139	COG0776	regulation of translation
ICG51_000141	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ICG51_000142	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ICG51_000144	COG2957	Belongs to the agmatine deiminase family
ICG51_000145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICG51_000154	COG1007	ATP synthesis coupled electron transport
ICG51_000160	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ICG51_000161	COG1034	ATP synthesis coupled electron transport
ICG51_000163	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ICG51_000164	COG0649	NAD binding
ICG51_000165	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICG51_000166	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICG51_000167	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICG51_000169	COG2081	HI0933 family
ICG51_000171	COG1054	Belongs to the UPF0176 family
ICG51_000173	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICG51_000175	COG3706	GGDEF domain
ICG51_000177	COG3279	Response regulator of the LytR AlgR family
ICG51_000181	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICG51_000182	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ICG51_000183	COG0505	Belongs to the CarA family
ICG51_000184	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ICG51_000187	COG0484	heat shock protein binding
ICG51_000188	COG0443	Heat shock 70 kDa protein
ICG51_000189	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICG51_000190	COG1420	regulation of RNA biosynthetic process
ICG51_000194	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICG51_000195	COG2925	Exonuclease
ICG51_000200	COG0484	heat shock protein binding
ICG51_000202	COG1596	polysaccharide export
ICG51_000204	COG3706	GGDEF domain
ICG51_000204	COG4251	negative regulation of phosphorylation
ICG51_000204	COG5001	Diguanylate cyclase
ICG51_000204	COG2203	Gaf domain
ICG51_000205	COG2895	sulfate adenylyltransferase (ATP) activity
ICG51_000205	COG0529	Catalyzes the synthesis of activated sulfate
ICG51_000206	COG0175	sulfate reduction
ICG51_000207	COG0069	glutamate synthase activity
ICG51_000213	COG4221	oxidoreductase activity
ICG51_000216	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ICG51_000217	COG3706	GGDEF domain
ICG51_000221	COG3590	peptidase
ICG51_000222	COG0251	oxidation-reduction process
ICG51_000223	COG3655	Transcriptional regulator
ICG51_000230	COG3038	cytochrome b561
ICG51_000231	COG0204	Acyl-transferase
ICG51_000237	COG0813	purine-nucleoside phosphorylase activity
ICG51_000238	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICG51_000239	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICG51_000248	COG3706	GGDEF domain
ICG51_000252	COG1136	(ABC) transporter
ICG51_000253	COG2119	membrane
ICG51_000257	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ICG51_000264	COG1187	pseudouridine synthase activity
ICG51_000270	COG1619	proteins homologs of microcin C7 resistance protein MccF
ICG51_000271	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ICG51_000275	COG0531	amino acid
ICG51_000277	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICG51_000278	COG0418	dihydroorotase activity
ICG51_000279	COG2199	diguanylate cyclase activity
ICG51_000279	COG2203	Gaf domain
ICG51_000290	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ICG51_000290	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ICG51_000290	COG1703	isobutyryl-CoA mutase activity
ICG51_000293	COG1960	acyl-CoA dehydrogenase activity
ICG51_000295	COG3706	GGDEF domain
ICG51_000297	COG2197	response regulator
ICG51_000299	COG0840	transmembrane signaling receptor activity
ICG51_000300	COG0835	chemotaxis
ICG51_000301	COG0840	transmembrane signaling receptor activity
ICG51_000303	COG0840	transmembrane signaling receptor activity
ICG51_000305	COG0840	transmembrane signaling receptor activity
ICG51_000306	COG5001	Diguanylate cyclase
ICG51_000308	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ICG51_000312	COG3243	poly(R)-hydroxyalkanoic acid synthase
ICG51_000314	COG1183	phosphatidylcholine synthase activity
ICG51_000316	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_000318	COG1064	alcohol dehydrogenase
ICG51_000323	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICG51_000324	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICG51_000329	COG2850	peptidyl-arginine hydroxylation
ICG51_000331	COG0567	Dehydrogenase, E1 component
ICG51_000336	COG0604	alcohol dehydrogenase
ICG51_000339	COG0678	peroxiredoxin activity
ICG51_000340	COG4953	penicillin-binding protein 1C
ICG51_000344	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ICG51_000352	COG2350	Protein conserved in bacteria
ICG51_000354	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICG51_000355	COG1187	pseudouridine synthase activity
ICG51_000362	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICG51_000363	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICG51_000364	COG0436	Aminotransferase
ICG51_000365	COG4133	protoheme IX ABC transporter activity
ICG51_000367	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ICG51_000373	COG3088	subunit of a heme lyase
ICG51_000375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICG51_000379	COG0438	transferase activity, transferring glycosyl groups
ICG51_000380	COG0671	phosphoesterase, PA-phosphatase related
ICG51_000381	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_000384	COG0288	reversible hydration of carbon dioxide
ICG51_000387	COG1185	polyribonucleotide nucleotidyltransferase activity
ICG51_000388	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICG51_000392	COG0195	Participates in both transcription termination and antitermination
ICG51_000393	COG0779	Required for maturation of 30S ribosomal subunits
ICG51_000395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICG51_000396	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ICG51_000398	COG1674	ftsk spoiiie
ICG51_000399	COG0686	Belongs to the AlaDH PNT family
ICG51_000400	COG0492	ferredoxin-NADP+ reductase activity
ICG51_000402	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ICG51_000405	COG5001	Diguanylate cyclase
ICG51_000405	COG5002	protein histidine kinase activity
ICG51_000420	COG0582	viral genome integration into host DNA
ICG51_000422	COG0840	transmembrane signaling receptor activity
ICG51_000423	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ICG51_000425	COG0019	diaminopimelate decarboxylase activity
ICG51_000428	COG4948	Mandelate Racemase Muconate Lactonizing
ICG51_000429	COG1737	Transcriptional regulator
ICG51_000431	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ICG51_000432	COG0460	homoserine dehydrogenase
ICG51_000432	COG0527	aspartate kinase activity
ICG51_000436	COG1012	belongs to the aldehyde dehydrogenase family
ICG51_000439	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ICG51_000445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ICG51_000446	COG1570	exodeoxyribonuclease VII activity
ICG51_000447	COG5001	Diguanylate cyclase
ICG51_000448	COG1595	DNA-templated transcription, initiation
ICG51_000450	COG1132	(ABC) transporter
ICG51_000454	COG0166	Belongs to the GPI family
ICG51_000455	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ICG51_000458	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ICG51_000459	COG0617	tRNA 3'-terminal CCA addition
ICG51_000461	COG1201	RNA secondary structure unwinding
ICG51_000462	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICG51_000465	COG1187	pseudouridine synthase activity
ICG51_000467	COG0705	Rhomboid family
ICG51_000469	COG0625	glutathione transferase activity
ICG51_000476	COG4774	siderophore transport
ICG51_000487	COG3275	phosphorelay sensor kinase activity
ICG51_000488	COG1611	Belongs to the LOG family
ICG51_000490	COG2095	MarC family integral membrane protein
ICG51_000491	COG0300	oxidoreductase activity
ICG51_000492	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ICG51_000501	COG2969	positive regulation of protein catabolic process
ICG51_000502	COG0625	glutathione transferase activity
ICG51_000503	COG2857	Cytochrome c1
ICG51_000504	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ICG51_000505	COG0723	plastoquinol--plastocyanin reductase activity
ICG51_000506	COG0741	lytic transglycosylase activity
ICG51_000509	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ICG51_000510	COG1702	phosphate starvation-inducible protein PhoH
ICG51_000511	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICG51_000512	COG4535	Mg2 and Co2 transporter CorC
ICG51_000516	COG1506	peptidase
ICG51_000516	COG0823	Involved in the tonB-independent uptake of proteins
ICG51_000517	COG1297	OPT oligopeptide transporter protein
ICG51_000522	COG0306	phosphate transporter
ICG51_000524	COG1253	flavin adenine dinucleotide binding
ICG51_000525	COG3300	MHYT domain
ICG51_000525	COG5001	Diguanylate cyclase
ICG51_000529	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICG51_000530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICG51_000531	COG1862	Preprotein translocase
ICG51_000532	COG0343	queuine tRNA-ribosyltransferase activity
ICG51_000533	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICG51_000534	COG1522	sequence-specific DNA binding
ICG51_000535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ICG51_000536	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ICG51_000542	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICG51_000543	COG0405	Gamma-glutamyltransferase
ICG51_000544	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICG51_000547	COG0742	ribosomal rna small subunit methyltransferase
ICG51_000548	COG0552	protein localization to endoplasmic reticulum
ICG51_000550	COG1194	a g-specific adenine glycosylase
ICG51_000551	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ICG51_000554	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ICG51_000555	COG4774	siderophore transport
ICG51_000560	COG0149	triose-phosphate isomerase activity
ICG51_000563	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICG51_000566	COG0133	tryptophan synthase activity
ICG51_000567	COG0135	phosphoribosylanthranilate isomerase activity
ICG51_000568	COG0101	tRNA pseudouridine synthase activity
ICG51_000570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICG51_000571	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ICG51_000572	COG2890	protein-(glutamine-N5) methyltransferase activity
ICG51_000573	COG1999	signal sequence binding
ICG51_000574	COG0688	phosphatidylethanolamine metabolic process
ICG51_000576	COG0753	catalase activity
ICG51_000591	COG3189	MarR family transcriptional regulator
ICG51_000594	COG0433	COG0433 Predicted ATPase
ICG51_000595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICG51_000597	COG0513	Belongs to the DEAD box helicase family
ICG51_000600	COG1960	acyl-CoA dehydrogenase activity
ICG51_000603	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ICG51_000604	COG3842	ATPase activity
ICG51_000605	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICG51_000606	COG1177	transmembrane transport
ICG51_000608	COG0116	Belongs to the methyltransferase superfamily
ICG51_000608	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICG51_000612	COG1946	Acyl-CoA thioesterase
ICG51_000615	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ICG51_000621	COG1073	alpha beta
ICG51_000630	COG0776	regulation of translation
ICG51_000633	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICG51_000635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICG51_000645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICG51_000646	COG0575	Belongs to the CDS family
ICG51_000647	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ICG51_000648	COG0750	zinc metalloprotease
ICG51_000652	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICG51_000653	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICG51_000657	COG0825	malonyl-CoA metabolic process
ICG51_000659	COG1722	exodeoxyribonuclease VII activity
ICG51_000660	COG0142	geranyltranstransferase activity
ICG51_000664	COG0312	modulator of DNA gyrase
ICG51_000666	COG0312	modulator of DNA gyrase
ICG51_000669	COG0424	maF-like protein
ICG51_000672	COG2261	transglycosylase associated protein
ICG51_000674	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICG51_000675	COG0175	sulfate reduction
ICG51_000677	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ICG51_000677	COG1648	precorrin-2 dehydrogenase activity
ICG51_000681	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ICG51_000682	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICG51_000683	COG0628	permease
ICG51_000686	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICG51_000689	COG3932	Exopolysaccharide synthesis, ExoD
ICG51_000691	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ICG51_000694	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ICG51_000697	COG0148	phosphopyruvate hydratase activity
ICG51_000698	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ICG51_000706	COG0791	NLP P60 protein
ICG51_000707	COG0791	NLP P60 protein
ICG51_000709	COG4948	Mandelate Racemase Muconate Lactonizing
ICG51_000711	COG2197	response regulator
ICG51_000714	COG0142	geranyltranstransferase activity
ICG51_000716	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICG51_000718	COG0527	aspartate kinase activity
ICG51_000720	COG0384	phenazine biosynthesis protein PhzF
ICG51_000727	COG1704	LemA family
ICG51_000731	COG1285	pathogenesis
ICG51_000732	COG0513	Belongs to the DEAD box helicase family
ICG51_000734	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ICG51_000736	COG0701	Predicted permease
ICG51_000739	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ICG51_000742	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ICG51_000743	COG1309	transcriptional regulator
ICG51_000746	COG0010	Belongs to the arginase family
ICG51_000747	COG1228	amidohydrolase
ICG51_000752	COG0735	belongs to the Fur family
ICG51_000754	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICG51_000756	COG2833	Protein of unknown function (DUF455)
ICG51_000759	COG0285	dihydrofolate synthase activity
ICG51_000766	COG0156	8-amino-7-oxononanoate synthase activity
ICG51_000767	COG1187	pseudouridine synthase activity
ICG51_000770	COG1902	pentaerythritol trinitrate reductase activity
ICG51_000770	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICG51_000772	COG0625	glutathione transferase activity
ICG51_000775	COG0039	L-malate dehydrogenase activity
ICG51_000778	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICG51_000779	COG1217	gtp-binding protein TYPA
ICG51_000782	COG0154	amidase activity
ICG51_000783	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ICG51_000784	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ICG51_000785	COG0203	ribosomal protein L17
ICG51_000787	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICG51_000790	COG0201	protein transport
ICG51_000791	COG0200	Binds to the 23S rRNA
ICG51_000792	COG1841	ribosomal large subunit assembly
ICG51_000794	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICG51_000795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICG51_000797	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICG51_000798	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICG51_000800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICG51_000801	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICG51_000803	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICG51_000804	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICG51_000805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICG51_000807	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICG51_000808	COG0089	rRNA binding
ICG51_000809	COG0088	Forms part of the polypeptide exit tunnel
ICG51_000810	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICG51_000811	COG0051	transcription antitermination factor activity, RNA binding
ICG51_000812	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICG51_000813	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICG51_000814	COG0049	tRNA binding
ICG51_000815	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICG51_000816	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICG51_000818	COG0222	ribosome binding
ICG51_000821	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICG51_000822	COG0250	Participates in transcription elongation, termination and antitermination
ICG51_000825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICG51_000830	COG0193	aminoacyl-tRNA hydrolase activity
ICG51_000832	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICG51_000834	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICG51_000835	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ICG51_000837	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ICG51_000838	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICG51_000843	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICG51_000844	COG1295	ribonuclease BN
ICG51_000847	COG0457	Tetratricopeptide repeat
ICG51_000849	COG3227	Zinc metalloprotease (Elastase)
ICG51_000850	COG2151	metal-sulfur cluster biosynthetic enzyme
ICG51_000852	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ICG51_000859	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICG51_000859	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICG51_000866	COG0583	DNA-binding transcription factor activity
ICG51_000868	COG2843	Capsule synthesis protein
ICG51_000872	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICG51_000875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICG51_000876	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICG51_000878	COG2096	Adenosyltransferase
ICG51_000879	COG0123	including yeast histone deacetylase and acetoin utilization protein
ICG51_000880	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ICG51_000881	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICG51_000882	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ICG51_000883	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICG51_000885	COG2967	ApaG domain
ICG51_000886	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ICG51_000889	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICG51_000890	COG0861	Integral membrane protein TerC family
ICG51_000891	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ICG51_000892	COG0577	efflux transmembrane transporter activity
ICG51_000892	COG1136	(ABC) transporter
ICG51_000893	COG1136	(ABC) transporter
ICG51_000894	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICG51_000895	COG0642	Histidine kinase
ICG51_000899	COG3956	TIGRFAM MazG family protein
ICG51_000900	COG1218	3'(2'),5'-bisphosphate nucleotidase
ICG51_000901	COG0494	nUDIX hydrolase
ICG51_000903	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ICG51_000906	COG0784	Response regulator, receiver
ICG51_000906	COG2198	Histidine kinase
ICG51_000906	COG0643	Histidine kinase
ICG51_000907	COG0840	transmembrane signaling receptor activity
ICG51_000911	COG0189	ligase activity
ICG51_000915	COG1199	ATP-dependent helicase activity
ICG51_000916	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ICG51_000920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICG51_000921	COG1643	Atp-dependent helicase
ICG51_000922	COG0783	Belongs to the Dps family
ICG51_000924	COG0514	ATP-dependent DNA helicase (RecQ)
ICG51_000925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICG51_000930	COG0488	(ABC) transporter
ICG51_000933	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ICG51_000935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ICG51_000937	COG0745	RESPONSE REGULATOR receiver
ICG51_000942	COG0471	metal ion transport
ICG51_000942	COG3273	potassium ion transport
ICG51_000946	COG1970	mechanosensitive ion channel activity
ICG51_000948	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ICG51_000949	COG0280	phosphate acetyltransferase
ICG51_000949	COG0281	malic enzyme
ICG51_000950	COG0786	glutamate:sodium symporter activity
ICG51_000951	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICG51_000953	COG1162	GTPase activity
ICG51_000954	COG0436	Aminotransferase
ICG51_000956	COG3038	cytochrome b561
ICG51_000960	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ICG51_000963	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ICG51_000966	COG1307	EDD domain protein, DegV family
ICG51_000970	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ICG51_000972	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ICG51_000975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ICG51_000976	COG2863	cytochrome
ICG51_000980	COG0730	response to heat
ICG51_000981	COG0741	lytic transglycosylase activity
ICG51_000982	COG0617	tRNA 3'-terminal CCA addition
ICG51_000986	COG0300	oxidoreductase activity
ICG51_000987	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICG51_000988	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICG51_000992	COG0358	DNA primase activity
ICG51_000993	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICG51_000993	COG2169	Transcriptional regulator
ICG51_000994	COG3145	DNA-N1-methyladenine dioxygenase activity
ICG51_000995	COG0109	protoheme IX farnesyltransferase activity
ICG51_000996	COG1612	heme a metabolic process
ICG51_001001	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ICG51_001004	COG1565	acr, cog1565
ICG51_001004	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ICG51_001008	COG0793	Belongs to the peptidase S41A family
ICG51_001009	COG4942	peptidase
ICG51_001010	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICG51_001012	COG2234	aminopeptidase activity
ICG51_001020	COG1773	rubredoxin
ICG51_001021	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ICG51_001022	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICG51_001024	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ICG51_001025	COG0346	lactoylglutathione lyase activity
ICG51_001026	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_001027	COG0671	phosphoesterase, PA-phosphatase related
ICG51_001028	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICG51_001029	COG0563	adenylate kinase activity
ICG51_001032	COG1872	DUF167
ICG51_001034	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ICG51_001035	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICG51_001042	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ICG51_001042	COG2755	lipolytic protein G-D-S-L family
ICG51_001047	COG0438	transferase activity, transferring glycosyl groups
ICG51_001051	COG0438	transferase activity, transferring glycosyl groups
ICG51_001055	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ICG51_001056	COG0237	dephospho-CoA kinase activity
ICG51_001057	COG0494	nUDIX hydrolase
ICG51_001059	COG0739	heme binding
ICG51_001064	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ICG51_001065	COG1181	Belongs to the D-alanine--D-alanine ligase family
ICG51_001066	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICG51_001069	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICG51_001070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ICG51_001071	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICG51_001073	COG3116	cell division
ICG51_001074	COG0275	rRNA processing
ICG51_001075	COG2001	Belongs to the MraZ family
ICG51_001079	COG3107	peptidoglycan biosynthetic process
ICG51_001080	COG0792	nuclease activity
ICG51_001081	COG0277	FAD linked oxidase domain protein
ICG51_001084	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICG51_001085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ICG51_001089	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICG51_001089	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICG51_001091	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICG51_001092	COG0488	(ABC) transporter
ICG51_001093	COG0284	orotidine-5'-phosphate decarboxylase activity
ICG51_001096	COG1450	Type ii and iii secretion system protein
ICG51_001099	COG3166	PFAM Fimbrial assembly family protein
ICG51_001100	COG3156	type II secretion system protein K
ICG51_001101	COG4795	General secretion pathway protein
ICG51_001102	COG2165	general secretion pathway protein
ICG51_001103	COG4970	Tfp pilus assembly protein FimT
ICG51_001104	COG2165	general secretion pathway protein
ICG51_001105	COG1459	type II secretion system
ICG51_001106	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICG51_001107	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICG51_001107	COG0047	phosphoribosylformylglycinamidine synthase activity
ICG51_001108	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ICG51_001109	COG4974	Belongs to the 'phage' integrase family
ICG51_001112	COG0795	lipopolysaccharide-transporting ATPase activity
ICG51_001114	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICG51_001119	COG2132	Multicopper oxidase
ICG51_001125	COG1752	Esterase of the alpha-beta hydrolase superfamily
ICG51_001126	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICG51_001127	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICG51_001128	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ICG51_001130	COG1956	GAF domain-containing protein
ICG51_001132	COG4206	TonB-dependent receptor
ICG51_001133	COG1309	transcriptional regulator
ICG51_001136	COG1136	(ABC) transporter
ICG51_001138	COG0295	cytidine deaminase activity
ICG51_001139	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ICG51_001140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ICG51_001143	COG1136	(ABC) transporter
ICG51_001143	COG0577	efflux transmembrane transporter activity
ICG51_001145	COG0577	efflux transmembrane transporter activity
ICG51_001145	COG1136	(ABC) transporter
ICG51_001148	COG4191	Histidine kinase
ICG51_001148	COG2205	protein histidine kinase activity
ICG51_001148	COG0745	RESPONSE REGULATOR receiver
ICG51_001150	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICG51_001158	COG0739	heme binding
ICG51_001159	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ICG51_001160	COG2807	transmembrane transport
ICG51_001162	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICG51_001164	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICG51_001167	COG2003	Belongs to the UPF0758 family
ICG51_001168	COG0018	arginyl-trna synthetase
ICG51_001170	COG4221	oxidoreductase activity
ICG51_001171	COG2755	lipolytic protein G-D-S-L family
ICG51_001171	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ICG51_001172	COG1166	arginine decarboxylase activity
ICG51_001174	COG3706	GGDEF domain
ICG51_001175	COG0347	Belongs to the P(II) protein family
ICG51_001177	COG0606	chelatase, subunit chli
ICG51_001181	COG3706	GGDEF domain
ICG51_001182	COG2224	Isocitrate lyase
ICG51_001183	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ICG51_001184	COG0583	DNA-binding transcription factor activity
ICG51_001189	COG4771	TonB-dependent receptor
ICG51_001193	COG1215	transferase activity, transferring glycosyl groups
ICG51_001199	COG0564	pseudouridine synthase activity
ICG51_001202	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICG51_001207	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICG51_001208	COG0318	PFAM AMP-dependent synthetase and ligase
ICG51_001211	COG0596	Alpha beta hydrolase
ICG51_001215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICG51_001217	COG0612	Peptidase, M16
ICG51_001222	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ICG51_001223	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICG51_001229	COG0697	spore germination
ICG51_001230	COG0408	coproporphyrinogen oxidase activity
ICG51_001234	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ICG51_001235	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ICG51_001235	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ICG51_001236	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ICG51_001237	COG1461	Dihydroxyacetone kinase
ICG51_001241	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ICG51_001247	COG3104	oligopeptide transport
ICG51_001248	COG3483	tryptophan 2,3-dioxygenase activity
ICG51_001251	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICG51_001255	COG0180	Tryptophanyl-tRNA synthetase
ICG51_001259	COG2323	membrane
ICG51_001261	COG1132	(ABC) transporter
ICG51_001263	COG0210	DNA helicase
ICG51_001266	COG0625	glutathione transferase activity
ICG51_001267	COG0823	Involved in the tonB-independent uptake of proteins
ICG51_001267	COG1506	peptidase
ICG51_001272	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ICG51_001279	COG0357	Ribosomal RNA small subunit methyltransferase G
ICG51_001280	COG1192	Involved in chromosome partitioning
ICG51_001281	COG1475	DNA binding
ICG51_001282	COG0463	Glycosyl transferase, family 2
ICG51_001286	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ICG51_001288	COG1968	undecaprenyl-diphosphatase activity
ICG51_001289	COG0174	glutamine synthetase
ICG51_001291	COG0347	Belongs to the P(II) protein family
ICG51_001292	COG0004	ammonium transporteR
ICG51_001294	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICG51_001295	COG0739	heme binding
ICG51_001297	COG3852	Histidine kinase
ICG51_001298	COG2204	response regulator
ICG51_001299	COG2032	superoxide dismutase activity
ICG51_001301	COG0183	Belongs to the thiolase family
ICG51_001302	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ICG51_001309	COG0493	'glutamate synthase
ICG51_001310	COG0070	glutamate synthase
ICG51_001310	COG0067	glutamate synthase
ICG51_001310	COG0069	glutamate synthase activity
ICG51_001313	COG2922	Belongs to the Smg family
ICG51_001314	COG0758	DNA mediated transformation
ICG51_001316	COG0242	peptide deformylase activity
ICG51_001318	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICG51_001318	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICG51_001319	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICG51_001324	COG1490	D-aminoacyl-tRNA deacylase activity
ICG51_001325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICG51_001326	COG0582	viral genome integration into host DNA
ICG51_001335	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ICG51_001336	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ICG51_001338	COG2205	protein histidine kinase activity
ICG51_001340	COG0210	DNA helicase
ICG51_001343	COG5377	YqaJ viral recombinase family
ICG51_001350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ICG51_001352	COG4983	Phage plasmid primase, P4 family domain protein
ICG51_001356	COG2205	protein histidine kinase activity
ICG51_001357	COG0745	RESPONSE REGULATOR receiver
ICG51_001358	COG1368	sulfuric ester hydrolase activity
ICG51_001366	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ICG51_001367	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICG51_001368	COG1127	ABC transporter
ICG51_001369	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ICG51_001370	COG1074	ATP-dependent DNA helicase activity
ICG51_001376	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICG51_001377	COG3122	Protein conserved in bacteria
ICG51_001378	COG0534	Mate efflux family protein
ICG51_001382	COG1960	acyl-CoA dehydrogenase activity
ICG51_001386	COG0302	gtp cyclohydrolase
ICG51_001396	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICG51_001402	COG1505	serine-type exopeptidase activity
ICG51_001405	COG2378	regulation of single-species biofilm formation
ICG51_001407	COG0181	hydroxymethylbilane synthase activity
ICG51_001415	COG0745	RESPONSE REGULATOR receiver
ICG51_001417	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICG51_001418	COG0861	Integral membrane protein TerC family
ICG51_001420	COG3647	Membrane
ICG51_001421	COG1752	Esterase of the alpha-beta hydrolase superfamily
ICG51_001424	COG1595	DNA-templated transcription, initiation
ICG51_001425	COG0302	gtp cyclohydrolase
ICG51_001426	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICG51_001428	COG3186	Phenylalanine-4-hydroxylase
ICG51_001429	COG5487	UPF0391 membrane protein
ICG51_001430	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ICG51_001431	COG0471	metal ion transport
ICG51_001431	COG3273	potassium ion transport
ICG51_001432	COG1741	Belongs to the pirin family
ICG51_001435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICG51_001445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICG51_001446	COG0592	DNA-directed DNA polymerase activity
ICG51_001450	COG0706	membrane insertase activity
ICG51_001454	COG4555	ABC transporter
ICG51_001463	COG1131	(ABC) transporter
ICG51_001464	COG0842	Transport permease protein
ICG51_001467	COG0084	hydrolase, TatD family'
ICG51_001468	COG1643	Atp-dependent helicase
ICG51_001470	COG2205	protein histidine kinase activity
ICG51_001471	COG1187	pseudouridine synthase activity
ICG51_001475	COG1652	LysM domain
ICG51_001476	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICG51_001476	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICG51_001477	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ICG51_001478	COG2945	thiolester hydrolase activity
ICG51_001487	COG1040	competence protein
ICG51_001488	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ICG51_001489	COG0156	8-amino-7-oxononanoate synthase activity
ICG51_001491	COG2267	carboxylic ester hydrolase activity
ICG51_001493	COG0697	spore germination
ICG51_001494	COG3437	response regulator, receiver
ICG51_001494	COG3850	Histidine kinase
ICG51_001494	COG4999	Histidine kinase
ICG51_001494	COG2205	protein histidine kinase activity
ICG51_001495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ICG51_001496	COG2201	protein-glutamate methylesterase activity
ICG51_001497	COG5002	protein histidine kinase activity
ICG51_001498	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICG51_001501	COG2911	Protein conserved in bacteria
ICG51_001502	COG0729	surface antigen
ICG51_001503	COG2703	oxygen carrier activity
ICG51_001506	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ICG51_001506	COG0519	Catalyzes the synthesis of GMP from XMP
ICG51_001512	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ICG51_001513	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICG51_001513	COG0596	Alpha beta hydrolase
ICG51_001517	COG0037	tRNA processing
ICG51_001519	COG2937	Belongs to the GPAT DAPAT family
ICG51_001520	COG3300	MHYT domain
ICG51_001520	COG5001	Diguanylate cyclase
ICG51_001523	COG0210	DNA helicase
ICG51_001527	COG1215	transferase activity, transferring glycosyl groups
ICG51_001532	COG2205	protein histidine kinase activity
ICG51_001532	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICG51_001534	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICG51_001539	COG1881	PFAM PEBP family protein
ICG51_001540	COG0515	serine threonine protein kinase
ICG51_001540	COG2815	serine threonine protein kinase
ICG51_001542	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ICG51_001545	COG1278	Cold shock
ICG51_001546	COG3590	peptidase
ICG51_001550	COG1238	metal cluster binding
ICG51_001551	COG2814	Major facilitator Superfamily
ICG51_001596	COG3162	membrane
ICG51_001598	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICG51_001600	COG2205	protein histidine kinase activity
ICG51_001602	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_001604	COG0616	signal peptide processing
ICG51_001605	COG0534	Mate efflux family protein
ICG51_001609	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICG51_001611	COG2860	membrane
ICG51_001614	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ICG51_001617	COG2022	thiamine diphosphate biosynthetic process
ICG51_001620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICG51_001622	COG2226	methyltransferase
ICG51_001623	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICG51_001625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ICG51_001626	COG3118	belongs to the thioredoxin family
ICG51_001628	COG2884	Cell division ATP-binding protein ftsE
ICG51_001629	COG2177	Part of the ABC transporter FtsEX involved in
ICG51_001630	COG2201	protein-glutamate methylesterase activity
ICG51_001632	COG0308	aminopeptidase N
ICG51_001633	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICG51_001633	COG0596	Alpha beta hydrolase
ICG51_001636	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICG51_001637	COG1077	Cell shape determining protein MreB Mrl
ICG51_001638	COG1792	Involved in formation and maintenance of cell shape
ICG51_001640	COG0768	penicillin binding
ICG51_001641	COG0772	Belongs to the SEDS family
ICG51_001642	COG2951	lytic endotransglycosylase activity
ICG51_001643	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICG51_001644	COG1686	Belongs to the peptidase S11 family
ICG51_001645	COG2921	Belongs to the UPF0250 family
ICG51_001646	COG0321	lipoyl(octanoyl) transferase activity
ICG51_001649	COG0697	spore germination
ICG51_001651	COG0577	efflux transmembrane transporter activity
ICG51_001652	COG0577	efflux transmembrane transporter activity
ICG51_001653	COG1136	(ABC) transporter
ICG51_001654	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICG51_001655	COG1131	(ABC) transporter
ICG51_001657	COG4585	Histidine kinase
ICG51_001658	COG2197	response regulator
ICG51_001664	COG0628	permease
ICG51_001677	COG0693	protein deglycase activity
ICG51_001687	COG3040	lipid binding
ICG51_001689	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ICG51_001692	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ICG51_001694	COG2824	Alkylphosphonate utilization operon protein PhnA
ICG51_001698	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_001701	COG2079	MmgE PrpD family protein
ICG51_001703	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICG51_001708	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ICG51_001709	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ICG51_001713	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICG51_001714	COG0134	indole-3-glycerol-phosphate synthase activity
ICG51_001718	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ICG51_001721	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ICG51_001722	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICG51_001723	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ICG51_001727	COG0625	glutathione transferase activity
ICG51_001733	COG1450	Type ii and iii secretion system protein
ICG51_001743	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICG51_001744	COG1459	type II secretion system
ICG51_001750	COG0438	transferase activity, transferring glycosyl groups
ICG51_001751	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ICG51_001754	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICG51_001759	COG2086	electron transfer activity
ICG51_001764	COG3218	ABC-type transport auxiliary lipoprotein component
ICG51_001764	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ICG51_001765	COG1127	ABC transporter
ICG51_001766	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICG51_001769	COG0442	prolyl-tRNA aminoacylation
ICG51_001772	COG1183	phosphatidylcholine synthase activity
ICG51_001775	COG0720	synthase
ICG51_001776	COG2906	2 iron, 2 sulfur cluster binding
ICG51_001791	COG1902	pentaerythritol trinitrate reductase activity
ICG51_001792	COG3384	dioxygenase
ICG51_001794	COG4181	ATPase activity
ICG51_001796	COG0151	Belongs to the GarS family
ICG51_001797	COG0138	bifunctional purine biosynthesis protein purh
ICG51_001798	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ICG51_001800	COG2264	protein methyltransferase activity
ICG51_001802	COG0439	Biotin carboxylase
ICG51_001803	COG0511	ligase activity, forming carbon-carbon bonds
ICG51_001804	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ICG51_001805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICG51_001807	COG1324	tolerance protein
ICG51_001812	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICG51_001813	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ICG51_001815	COG0778	Nitroreductase
ICG51_001816	COG2353	YceI-like domain
ICG51_001817	COG1741	Belongs to the pirin family
ICG51_001819	COG0297	glycogen (starch) synthase activity
ICG51_001821	COG1560	Kdo2-lipid A biosynthetic process
ICG51_001822	COG1519	Transferase
ICG51_001823	COG1538	Outer membrane efflux protein
ICG51_001824	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ICG51_001828	COG3300	MHYT domain
ICG51_001828	COG5001	Diguanylate cyclase
ICG51_001830	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICG51_001831	COG0066	3-isopropylmalate dehydratase activity
ICG51_001832	COG0473	3-isopropylmalate dehydrogenase activity
ICG51_001833	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ICG51_001837	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ICG51_001838	COG0129	dihydroxy-acid dehydratase activity
ICG51_001841	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICG51_001846	COG3079	Belongs to the UPF0149 family
ICG51_001847	COG0006	proline dipeptidase activity
ICG51_001848	COG0006	proline dipeptidase activity
ICG51_001851	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ICG51_001852	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICG51_001853	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ICG51_001854	COG1561	YicC-like family, N-terminal region
ICG51_001855	COG0194	GDP metabolic process
ICG51_001856	COG1758	RNA polymerase activity
ICG51_001857	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICG51_001859	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICG51_001863	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICG51_001867	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICG51_001869	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ICG51_001869	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICG51_001881	COG0789	Transcriptional regulator
ICG51_001888	COG0640	Transcriptional regulator
ICG51_001889	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICG51_001890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICG51_001899	COG0254	rRNA binding
ICG51_001900	COG0372	Belongs to the citrate synthase family
ICG51_001902	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ICG51_001908	COG0714	Associated with various cellular activities
ICG51_001914	COG1301	dicarboxylic acid transport
ICG51_001915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICG51_001919	COG3682	Transcriptional regulator
ICG51_001923	COG3047	cAMP biosynthetic process
ICG51_001924	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ICG51_001925	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ICG51_001931	COG0126	phosphoglycerate kinase activity
ICG51_001933	COG0469	pyruvate kinase activity
ICG51_001935	COG3588	fructose-bisphosphate aldolase
ICG51_001938	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICG51_001946	COG3275	phosphorelay sensor kinase activity
ICG51_001947	COG1793	dna ligase
ICG51_001948	COG3795	YCII-related domain
ICG51_001949	COG3795	YCII-related domain
ICG51_001950	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ICG51_001952	COG4941	Belongs to the sigma-70 factor family
ICG51_001958	COG2813	Specifically methylates the guanine in position
ICG51_001959	COG1187	pseudouridine synthase activity
ICG51_001961	COG1666	GTP binding
ICG51_001962	COG0697	spore germination
ICG51_001963	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICG51_001964	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICG51_001967	COG0356	it plays a direct role in the translocation of protons across the membrane
ICG51_001969	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICG51_001970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICG51_001971	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICG51_001972	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICG51_001973	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICG51_001974	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ICG51_001977	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ICG51_001979	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICG51_001980	COG0564	pseudouridine synthase activity
ICG51_001985	COG0542	response to heat
ICG51_001986	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICG51_001986	COG4651	solute:proton antiporter activity
ICG51_001988	COG0488	(ABC) transporter
ICG51_001991	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ICG51_001995	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ICG51_001996	COG0632	four-way junction helicase activity
ICG51_001998	COG5001	Diguanylate cyclase
ICG51_001999	COG2255	four-way junction helicase activity
ICG51_002000	COG0824	Thioesterase
ICG51_002002	COG0848	biopolymer transport protein
ICG51_002005	COG2885	chlorophyll binding
ICG51_002007	COG0602	queuosine metabolic process
ICG51_002008	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ICG51_002010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICG51_002011	COG2211	Major facilitator Superfamily
ICG51_002013	COG0330	HflC and HflK could
ICG51_002019	COG1704	LemA family
ICG51_002020	COG0501	Belongs to the peptidase M48B family
ICG51_002024	COG1960	acyl-CoA dehydrogenase activity
ICG51_002025	COG1309	transcriptional regulator
ICG51_002026	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ICG51_002028	COG0457	Tetratricopeptide repeat
ICG51_002035	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICG51_002037	COG0463	Glycosyl transferase, family 2
ICG51_002038	COG0617	tRNA 3'-terminal CCA addition
ICG51_002038	COG3620	sequence-specific DNA binding
ICG51_002038	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ICG51_002041	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICG51_002043	COG0739	heme binding
ICG51_002044	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICG51_002045	COG0626	cystathionine gamma-synthase activity
ICG51_002046	COG0460	homoserine dehydrogenase
ICG51_002046	COG0527	aspartate kinase activity
ICG51_002047	COG5002	protein histidine kinase activity
ICG51_002047	COG5001	Diguanylate cyclase
ICG51_002048	COG3706	GGDEF domain
ICG51_002049	COG1760	l-serine dehydratase
ICG51_002052	COG3038	cytochrome b561
ICG51_002054	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ICG51_002059	COG0259	pyridoxamine-phosphate oxidase activity
ICG51_002060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ICG51_002063	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ICG51_002066	COG1678	Uncharacterized ACR, COG1678
ICG51_002067	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICG51_002068	COG0540	Belongs to the ATCase OTCase family
ICG51_002070	COG2239	Acts as a magnesium transporter
ICG51_002071	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICG51_002078	COG1137	ATPase activity
ICG51_002079	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ICG51_002081	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ICG51_002083	COG0271	Belongs to the BolA IbaG family
ICG51_002084	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICG51_002095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICG51_002097	COG2354	Protein conserved in bacteria
ICG51_002098	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ICG51_002099	COG0745	RESPONSE REGULATOR receiver
ICG51_002100	COG2205	protein histidine kinase activity
ICG51_002101	COG4452	Inner membrane protein CreD
ICG51_002104	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ICG51_002109	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICG51_002110	COG0473	3-isopropylmalate dehydrogenase activity
ICG51_002117	COG0544	peptidyl-prolyl cis-trans isomerase activity
ICG51_002119	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICG51_002124	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICG51_002126	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICG51_002129	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICG51_002130	COG0631	protein serine/threonine phosphatase activity
ICG51_002133	COG0859	PFAM glycosyl transferase family 9
ICG51_002134	COG3642	lipopolysaccharide core region biosynthetic process
ICG51_002140	COG0537	adenosine 5'-monophosphoramidase activity
ICG51_002144	COG0714	Associated with various cellular activities
ICG51_002149	COG1399	metal-binding, possibly nucleic acid-binding protein
ICG51_002150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ICG51_002151	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICG51_002152	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ICG51_002156	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICG51_002157	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ICG51_002158	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICG51_002159	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICG51_002162	COG1725	Transcriptional regulator
ICG51_002163	COG1131	(ABC) transporter
ICG51_002167	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICG51_002167	COG1024	Enoyl-CoA hydratase
ICG51_002170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICG51_002171	COG0481	GTPase activity
ICG51_002172	COG0681	Belongs to the peptidase S26 family
ICG51_002175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICG51_002176	COG1381	Involved in DNA repair and RecF pathway recombination
ICG51_002177	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICG51_002179	COG1534	Rna-binding protein
ICG51_002180	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ICG51_002181	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICG51_002182	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ICG51_002183	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICG51_002184	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICG51_002185	COG1923	regulation of RNA biosynthetic process
ICG51_002186	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICG51_002187	COG0330	HflC and HflK could
ICG51_002188	COG0330	HflC and HflK could
ICG51_002192	COG1272	protein, Hemolysin III
ICG51_002193	COG0308	aminopeptidase N
ICG51_002196	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ICG51_002197	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICG51_002198	COG4206	TonB-dependent receptor
ICG51_002199	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICG51_002199	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICG51_002200	COG2814	Major facilitator Superfamily
ICG51_002201	COG0531	amino acid
ICG51_002206	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ICG51_002207	COG2894	cell division
ICG51_002208	COG0850	regulation of cytokinetic process
ICG51_002210	COG4585	Histidine kinase
ICG51_002211	COG2197	response regulator
ICG51_002214	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ICG51_002219	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ICG51_002221	COG4974	Belongs to the 'phage' integrase family
ICG51_002241	COG0515	serine threonine protein kinase
ICG51_002241	COG2815	serine threonine protein kinase
ICG51_002243	COG3118	belongs to the thioredoxin family
ICG51_002248	COG4095	Psort location CytoplasmicMembrane, score
ICG51_002256	COG0495	leucyl-tRNA aminoacylation
ICG51_002259	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICG51_002264	COG0052	Belongs to the universal ribosomal protein uS2 family
ICG51_002265	COG0024	Methionine aminopeptidase
ICG51_002269	COG1393	Belongs to the ArsC family
ICG51_002270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ICG51_002271	COG0367	asparagine synthase
ICG51_002279	COG2010	Cytochrome c
ICG51_002282	COG3278	Belongs to the heme-copper respiratory oxidase family
ICG51_002283	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICG51_002286	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ICG51_002292	COG3154	lipid carrier protein
ICG51_002294	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ICG51_002295	COG0826	peptidase U32
ICG51_002296	COG0826	peptidase U32
ICG51_002298	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ICG51_002299	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ICG51_002304	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICG51_002305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ICG51_002306	COG0500	methyltransferase
ICG51_002309	COG2885	chlorophyll binding
ICG51_002311	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ICG51_002312	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICG51_002312	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ICG51_002313	COG0802	atpase or kinase
ICG51_002318	COG2878	Part of a membrane complex involved in electron transport
ICG51_002320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICG51_002320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICG51_002324	COG4771	TonB-dependent receptor
ICG51_002326	COG4771	TonB-dependent receptor
ICG51_002327	COG0489	protein tyrosine kinase activity
ICG51_002328	COG0717	Belongs to the dCTP deaminase family
ICG51_002330	COG0412	Dienelactone hydrolase
ICG51_002333	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ICG51_002334	COG0612	Peptidase, M16
ICG51_002342	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICG51_002343	COG0719	Fe-S assembly protein
ICG51_002344	COG0396	ATPase activity
ICG51_002345	COG0719	Fe-S assembly protein
ICG51_002360	COG0457	Tetratricopeptide repeat
ICG51_002361	COG4771	TonB-dependent receptor
ICG51_002367	COG1981	membrane
ICG51_002369	COG1301	dicarboxylic acid transport
ICG51_002372	COG1877	trehalose-phosphatase activity
ICG51_002373	COG3387	PFAM Glycoside hydrolase 15-related
ICG51_002374	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ICG51_002377	COG0516	GMP reductase activity
ICG51_002377	COG0517	IMP dehydrogenase activity
ICG51_002387	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_002391	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICG51_002394	COG0587	DNA-directed DNA polymerase activity
ICG51_002396	COG0557	exoribonuclease II activity
ICG51_002397	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICG51_002399	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICG51_002403	COG0704	Plays a role in the regulation of phosphate uptake
ICG51_002407	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ICG51_002410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICG51_002412	COG1024	Enoyl-CoA hydratase
ICG51_002415	COG0494	nUDIX hydrolase
ICG51_002419	COG0824	Thioesterase
ICG51_002420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ICG51_002423	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ICG51_002424	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICG51_002427	COG0196	riboflavin kinase activity
ICG51_002430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ICG51_002432	COG0582	viral genome integration into host DNA
ICG51_002445	COG2814	Major facilitator Superfamily
ICG51_002446	COG1566	PFAM secretion protein HlyD family protein
ICG51_002448	COG1846	Transcriptional regulator
ICG51_002449	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ICG51_002452	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ICG51_002453	COG0315	cyclic pyranopterin monophosphate synthase activity
ICG51_002453	COG0521	Mo-molybdopterin cofactor biosynthetic process
ICG51_002454	COG0303	'Molybdopterin
ICG51_002456	COG0314	molybdopterin synthase activity
ICG51_002458	COG2223	nitrite transmembrane transporter activity
ICG51_002459	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICG51_002460	COG1140	nitrate reductase beta subunit
ICG51_002461	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ICG51_002462	COG2181	nitrate reductase activity
ICG51_002463	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICG51_002466	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ICG51_002469	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICG51_002470	COG4269	membrane
ICG51_002472	COG0228	four-way junction DNA binding
ICG51_002473	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICG51_002474	COG0336	Belongs to the RNA methyltransferase TrmD family
ICG51_002478	COG0625	glutathione transferase activity
ICG51_002479	COG3773	Cell wall hydrolase
ICG51_002479	COG3409	Peptidoglycan-binding domain 1 protein
ICG51_002481	COG1522	sequence-specific DNA binding
ICG51_002482	COG0626	cystathionine gamma-synthase activity
ICG51_002485	COG0753	catalase activity
ICG51_002486	COG2258	MOSC domain
ICG51_002491	COG1546	Belongs to the CinA family
ICG51_002493	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICG51_002494	COG2137	regulation of response to DNA damage stimulus
ICG51_002495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICG51_002496	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICG51_002502	COG0784	Response regulator, receiver
ICG51_002502	COG2205	protein histidine kinase activity
ICG51_002502	COG5002	protein histidine kinase activity
ICG51_002513	COG0366	Alpha amylase catalytic
ICG51_002514	COG1082	Xylose isomerase domain protein TIM barrel
ICG51_002516	COG0800	Aldolase
ICG51_002520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICG51_002524	COG0659	secondary active sulfate transmembrane transporter activity
ICG51_002525	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ICG51_002526	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ICG51_002528	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICG51_002530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ICG51_002532	COG2166	iron-sulfur cluster assembly
ICG51_002535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICG51_002536	COG0137	argininosuccinate synthase activity
ICG51_002537	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ICG51_002538	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ICG51_002539	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ICG51_002540	COG0165	Argininosuccinate lyase
ICG51_002542	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICG51_002549	COG1360	Flagellar Motor Protein
ICG51_002569	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICG51_002569	COG4797	methyltransferase
ICG51_002570	COG2205	protein histidine kinase activity
ICG51_002572	COG0124	histidyl-tRNA synthetase
ICG51_002573	COG2986	histidine ammonia-lyase
ICG51_002577	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ICG51_002578	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICG51_002579	COG0131	Imidazoleglycerol-phosphate dehydratase
ICG51_002579	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ICG51_002580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICG51_002583	COG0140	phosphoribosyl-ATP diphosphatase activity
ICG51_002583	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICG51_002587	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ICG51_002588	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ICG51_002589	COG0235	Class ii aldolase
ICG51_002590	COG0235	Class ii aldolase
ICG51_002591	COG0531	amino acid
ICG51_002593	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICG51_002594	COG0277	FAD linked oxidase domain protein
ICG51_002601	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICG51_002608	COG1024	Enoyl-CoA hydratase
ICG51_002615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ICG51_002616	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICG51_002617	COG2954	triphosphatase activity
ICG51_002618	COG1472	Belongs to the glycosyl hydrolase 3 family
ICG51_002620	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ICG51_002624	COG0183	Belongs to the thiolase family
ICG51_002626	COG2915	High frequency lysogenization protein hflD homolog
ICG51_002627	COG0482	sulfurtransferase activity
ICG51_002630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ICG51_002631	COG0542	response to heat
ICG51_002635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICG51_002646	COG0477	Major facilitator Superfamily
ICG51_002648	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICG51_002650	COG2610	gluconate transmembrane transporter activity
ICG51_002652	COG0784	Response regulator, receiver
ICG51_002652	COG2205	protein histidine kinase activity
ICG51_002652	COG2198	Histidine kinase
ICG51_002653	COG2197	response regulator
ICG51_002654	COG1530	ribonuclease E activity
ICG51_002656	COG2154	pterin-4-alpha-carbinolamine dehydratase
ICG51_002657	COG0316	Belongs to the HesB IscA family
ICG51_002657	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ICG51_002661	COG0017	Asparaginyl-tRNA synthetase
ICG51_002662	COG0316	Belongs to the HesB IscA family
ICG51_002663	COG0360	Binds together with S18 to 16S ribosomal RNA
ICG51_002664	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICG51_002665	COG0359	binds to the 23S rRNA
ICG51_002666	COG0305	Participates in initiation and elongation during chromosome replication
ICG51_002667	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICG51_002669	COG2885	chlorophyll binding
ICG51_002672	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ICG51_002677	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_002679	COG0501	Belongs to the peptidase M48B family
ICG51_002680	COG5001	Diguanylate cyclase
ICG51_002680	COG5002	protein histidine kinase activity
ICG51_002681	COG1509	lysine 2,3-aminomutase activity
ICG51_002683	COG0402	S-adenosylhomocysteine deaminase activity
ICG51_002687	COG1469	GTP cyclohydrolase I activity
ICG51_002689	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ICG51_002692	COG0339	signal peptide processing
ICG51_002693	COG0386	Belongs to the glutathione peroxidase family
ICG51_002698	COG2133	pyrroloquinoline quinone binding
ICG51_002703	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ICG51_002704	COG0084	hydrolase, TatD family'
ICG51_002706	COG3134	Outer membrane lipoprotein
ICG51_002707	COG1960	acyl-CoA dehydrogenase activity
ICG51_002709	COG0625	glutathione transferase activity
ICG51_002710	COG0022	dehydrogenase e1 component
ICG51_002711	COG0028	Belongs to the TPP enzyme family
ICG51_002716	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ICG51_002717	COG1053	succinate dehydrogenase
ICG51_002721	COG4591	ABC-type transport system involved in lipoprotein release permease component
ICG51_002723	COG2333	competence protein COMEC
ICG51_002723	COG0658	competence protein
ICG51_002724	COG0811	peptide transport
ICG51_002727	COG1663	tetraacyldisaccharide 4'-kinase activity
ICG51_002728	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ICG51_002729	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICG51_002730	COG0322	excinuclease ABC activity
ICG51_002731	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICG51_002740	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICG51_002742	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICG51_002743	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ICG51_002747	COG1131	(ABC) transporter
ICG51_002748	COG1725	Transcriptional regulator
ICG51_002750	COG0545	Peptidyl-prolyl cis-trans isomerase
ICG51_002753	COG2900	Belongs to the SlyX family
ICG51_002755	COG1410	methionine synthase
ICG51_002755	COG0646	methionine synthase
ICG51_002758	COG1960	acyl-CoA dehydrogenase activity
ICG51_002759	COG2902	Dehydrogenase
ICG51_002761	COG5001	Diguanylate cyclase
ICG51_002761	COG5002	protein histidine kinase activity
ICG51_002764	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ICG51_002765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ICG51_002768	COG0438	transferase activity, transferring glycosyl groups
ICG51_002771	COG0438	transferase activity, transferring glycosyl groups
ICG51_002774	COG0438	transferase activity, transferring glycosyl groups
ICG51_002775	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ICG51_002781	COG0318	PFAM AMP-dependent synthetase and ligase
ICG51_002784	COG3706	GGDEF domain
ICG51_002788	COG2409	Drug exporters of the RND superfamily
ICG51_002790	COG0745	RESPONSE REGULATOR receiver
ICG51_002792	COG0835	chemotaxis
ICG51_002793	COG1192	Involved in chromosome partitioning
ICG51_002794	COG1360	Flagellar Motor Protein
ICG51_002795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ICG51_002796	COG2198	Histidine kinase
ICG51_002796	COG0784	Response regulator, receiver
ICG51_002796	COG0643	Histidine kinase
ICG51_002797	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ICG51_002805	COG1987	bacterial-type flagellum assembly
ICG51_002811	COG3144	bacterial-type flagellum assembly
ICG51_002817	COG1677	Flagellar hook-basal body complex protein FliE
ICG51_002819	COG2201	protein-glutamate methylesterase activity
ICG51_002834	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ICG51_002835	COG4786	Flagellar basal body rod
ICG51_002836	COG4787	bacterial-type flagellum-dependent cell motility
ICG51_002837	COG1749	Flagellar hook protein flgE
ICG51_002839	COG1558	bacterial-type flagellum-dependent cell motility
ICG51_002840	COG1815	bacterial-type flagellum-dependent cell motility
ICG51_002841	COG0835	chemotaxis
ICG51_002841	COG0784	Response regulator, receiver
ICG51_002849	COG3384	dioxygenase