locus-tag	class	description
TALC_00005	ENOG4105EBX	v-type atpase
TALC_00010	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TALC_00011	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
TALC_00012	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TALC_00022	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TALC_00024	ENOG4105CJ1	ABC, transporter
TALC_00026	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TALC_00033	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TALC_00034	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TALC_00035	ENOG4105K56	Transcriptional regulator
TALC_00041	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TALC_00047	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
TALC_00056	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TALC_00057	ENOG4105C6K	Malic enzyme
TALC_00063	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
TALC_00066	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TALC_00068	ENOG4105K64	Glycosyl transferase, family 2
TALC_00076	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TALC_00080	ENOG4105KPE	licD family
TALC_00081	ENOG4107STF	Involved in phosphonate degradation (By similarity)
TALC_00082	ENOG4105DTI	Phosphonopyruvate decarboxylase
TALC_00083	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
TALC_00085	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
TALC_00086	ENOG4108IJ1	Dehydrogenase
TALC_00094	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
TALC_00095	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
TALC_00096	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TALC_00097	ENOG4105C7K	acetolactate synthase
TALC_00099	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TALC_00100	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
TALC_00101	ENOG4105CKK	Glycosyl transferase, family 2
TALC_00103	ENOG4108SMP	Nad-dependent epimerase dehydratase
TALC_00107	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
TALC_00115	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TALC_00116	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TALC_00119	ENOG4105EM7	Selenocysteine-specific translation elongation factor
TALC_00122	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
TALC_00125	ENOG4105EVN	Prephenate dehydrogenase
TALC_00128	ENOG41079KZ	Major Facilitator Superfamily
TALC_00141	ENOG41063C6	UPF0235 protein
TALC_00143	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TALC_00147	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TALC_00148	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TALC_00151	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
TALC_00152	ENOG4108DGI	Phosphoribosylformylglycinamidine synthase I
TALC_00162	ENOG4105E0A	ABC, transporter
TALC_00164	ENOG4105EHG	Permease protein
TALC_00170	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
TALC_00175	ENOG4105CHM	Aminotransferase
TALC_00179	ENOG4105DVT	helicase
TALC_00185	ENOG4105DC1	bifunctional purine biosynthesis protein purh
TALC_00188	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TALC_00194	ENOG4108IUS	Transketolase
TALC_00195	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
TALC_00197	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TALC_00199	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TALC_00200	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
TALC_00201	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
TALC_00203	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TALC_00206	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TALC_00208	ENOG4105II7	pyrroline-5-carboxylate reductase
TALC_00209	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TALC_00210	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TALC_00211	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TALC_00212	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TALC_00214	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TALC_00215	ENOG4107UFS	subunit j
TALC_00217	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TALC_00218	ENOG4105D65	subunit l
TALC_00219	ENOG4105C8S	subunit m
TALC_00220	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TALC_00222	ENOG4105EAH	synthase
TALC_00226	ENOG4107YIW	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TALC_00227	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TALC_00228	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
TALC_00233	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TALC_00236	ENOG4108I5D	sulfate abc transporter
TALC_00237	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TALC_00239	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TALC_00241	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TALC_00243	ENOG4105CYW	agmatinase
TALC_00246	ENOG4105FB2	class II Aldolase
TALC_00247	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TALC_00248	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TALC_00249	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
TALC_00252	ENOG4105D7A	ATP-binding protein
TALC_00254	ENOG4105C26	Dehydrogenase
TALC_00265	ENOG4105C8M	UPF0272 protein
TALC_00266	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
TALC_00273	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
TALC_00274	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
TALC_00280	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TALC_00283	ENOG4105CE1	Ferrous iron transport protein b
TALC_00290	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
TALC_00295	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TALC_00300	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TALC_00307	ENOG4105E66	phosphoriboisomerase A
TALC_00309	ENOG4105C59	p-type ATPase
TALC_00315	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TALC_00316	ENOG4105C57	major facilitator superfamily
TALC_00317	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TALC_00319	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TALC_00320	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TALC_00326	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TALC_00328	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TALC_00334	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TALC_00337	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TALC_00345	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
TALC_00348	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
TALC_00349	ENOG4105CEY	Amp-dependent synthetase and ligase
TALC_00351	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TALC_00384	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TALC_00388	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TALC_00389	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TALC_00390	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TALC_00391	ENOG4105C01	Dihydroxy-acid dehydratase
TALC_00394	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TALC_00413	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TALC_00416	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TALC_00418	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
TALC_00421	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TALC_00423	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TALC_00426	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TALC_00427	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TALC_00428	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TALC_00431	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TALC_00438	ENOG4105CHM	Aminotransferase
TALC_00441	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TALC_00442	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TALC_00449	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
TALC_00450	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TALC_00452	ENOG4105D1F	ATP-binding protein
TALC_00456	ENOG4105EHG	Permease protein
TALC_00460	ENOG4105DCI	Phosphohydrolase
TALC_00466	ENOG4105DBV	ornithine carbamoyltransferase
TALC_00478	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
TALC_00483	ENOG4105CIZ	coA-substrate-specific enzyme activase
TALC_00487	ENOG4105CQB	FAD linked oxidase domain protein
TALC_00492	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TALC_00497	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
TALC_00498	ENOG410814C	multidrug resistance protein
TALC_00500	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
TALC_00501	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TALC_00503	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TALC_00513	ENOG4105F8V	Hydrolase, tatD family
TALC_00514	ENOG4105D06	uba thif-type nad fad binding protein
TALC_00515	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TALC_00521	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TALC_00523	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
TALC_00531	ENOG4108K7V	UPF0284 protein
TALC_00532	ENOG4108K7V	UPF0284 protein
TALC_00534	ENOG4105C8H	hydrogenase maturation protein Hypf
TALC_00535	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
TALC_00541	ENOG4108JB8	alcohol dehydrogenase
TALC_00543	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TALC_00544	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TALC_00545	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TALC_00548	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
TALC_00549	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TALC_00550	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TALC_00551	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TALC_00552	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TALC_00553	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TALC_00554	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TALC_00555	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TALC_00557	ENOG4107SDT	Homocitrate synthase
TALC_00558	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
TALC_00560	ENOG41061GT	Aldolase
TALC_00561	ENOG4106M32	3-dehydroquinate synthase
TALC_00562	ENOG4105E2X	shikimate dehydrogenase
TALC_00563	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TALC_00564	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TALC_00565	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TALC_00567	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
TALC_00568	ENOG4105D06	uba thif-type nad fad binding protein
TALC_00572	ENOG4105C5H	ABC transporter
TALC_00573	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TALC_00577	ENOG4108WS4	fmn reductase
TALC_00584	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
TALC_00586	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
TALC_00587	ENOG4105KJF	protein tyrosine phosphatase
TALC_00589	ENOG4107QM5	aconitate hydratase
TALC_00591	ENOG4105CSR	polyphosphate kinase 2
TALC_00592	ENOG4105CSR	polyphosphate kinase 2
TALC_00595	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TALC_00598	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TALC_00601	ENOG4105CQR	helicase
TALC_00603	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TALC_00604	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TALC_00605	ENOG4105CEV	competence damage-inducible protein
TALC_00606	ENOG4105C8V	SAICAR synthetase
TALC_00609	ENOG4105DCT	glycerol dehydrogenase
TALC_00613	ENOG4105MAX	Superoxide reductase
TALC_00615	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TALC_00621	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TALC_00622	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
TALC_00624	ENOG4105DWF	phosphomethylpyrimidine kinase
TALC_00626	ENOG4108IQK	o-acetylhomoserine
TALC_00627	ENOG4105CH7	arginosuccinase
TALC_00628	ENOG4105CDH	Citrulline--aspartate ligase
TALC_00629	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TALC_00630	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
TALC_00631	ENOG4105CAS	nag kinase
TALC_00632	ENOG4105C8Y	Acetylornithine aminotransferase
TALC_00634	ENOG4105C1J	atp-dependent rna helicase
TALC_00639	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TALC_00648	ENOG4105C4X	radical SAM domain protein
TALC_00649	ENOG4105KME	endoribonuclease L-psp
TALC_00650	ENOG4105CVG	Homoserine O-transsuccinylase
TALC_00651	ENOG4105C6T	cysteine synthase
TALC_00655	ENOG4105EGD	dinuclear metal center protein, YbgI family
TALC_00658	ENOG4105C5H	ABC transporter
TALC_00660	ENOG4105C3S	Mate efflux family protein
TALC_00661	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TALC_00662	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TALC_00665	ENOG4105E4P	ATPase (AAA
TALC_00670	ENOG41061GT	Aldolase
TALC_00676	ENOG4105C0P	Mg chelatase subunit ChlI
TALC_00677	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TALC_00678	ENOG4106D4I	domain protein
TALC_00679	ENOG4107VRP	DNA repair exonuclease
TALC_00681	ENOG4107NFR	Fructose-1,6-bisphosphatase
TALC_00682	ENOG4105C5S	asparaginyl-tRNA synthetase
TALC_00684	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
TALC_00686	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
TALC_00687	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TALC_00689	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TALC_00691	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
TALC_00692	ENOG41062JF	Transcriptional regulator
TALC_00693	ENOG4105EYF	MMPL domain protein
TALC_00694	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TALC_00697	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TALC_00701	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TALC_00702	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
TALC_00704	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TALC_00706	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
TALC_00708	ENOG4105D8X	mechanosensitive ion channel
TALC_00711	ENOG4105CHM	Aminotransferase
TALC_00713	ENOG4105D7W	serine acetyltransferase
TALC_00714	ENOG4105C8N	cysteinyl-tRNA synthetase
TALC_00715	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TALC_00718	ENOG4105C6E	dna polymerase iii
TALC_00719	ENOG4105DZS	Phenylacetate-CoA ligase
TALC_00725	ENOG4105CKU	formyltetrahydrofolate synthetase
TALC_00727	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TALC_00729	ENOG4107YCR	Transcriptional regulator, ARSR family
TALC_00730	ENOG4105C59	p-type ATPase
TALC_00731	ENOG4105CFG	Acts as a chaperone (By similarity)
TALC_00735	ENOG4105CFG	Acts as a chaperone (By similarity)
TALC_00736	ENOG4105FE9	pseudouridine synthase
TALC_00737	ENOG4105EUB	pirin domain protein
TALC_00738	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TALC_00740	ENOG4105KVH	Transcriptional regulator
TALC_00750	ENOG4105C7N	Xanthine uracil vitamin C permease
TALC_00752	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
TALC_00753	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
TALC_00754	ENOG4107R33	ppx gppa phosphatase
TALC_00757	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TALC_00761	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TALC_00763	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TALC_00766	ENOG4107Y5K	Resolvase
TALC_00767	ENOG4107Y5K	Resolvase
TALC_00771	ENOG4105CZM	Major Facilitator
TALC_00772	ENOG4107YUH	hydrolase
TALC_00774	ENOG4107WAP	fad NAD(P)-binding domain
TALC_00781	ENOG4107SET	aldo keto reductase
TALC_00782	ENOG4105CCT	upf0313 protein
TALC_00787	ENOG4105DVT	helicase
TALC_00796	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
TALC_00821	ENOG4105DZR	Type I site-specific deoxyribonuclease
TALC_00829	ENOG4105EHG	Permease protein
TALC_00830	ENOG4105E0A	ABC, transporter
TALC_00889	ENOG4105DKW	ABC transporter
TALC_00892	ENOG4105CNW	domain protein
TALC_00894	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
TALC_00896	ENOG4105D5T	phosphonate abc transporter
TALC_00897	ENOG4105EHG	Permease protein
TALC_00911	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
TALC_00912	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TALC_00918	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TALC_00921	ENOG4105C83	adenylosuccinate lyase
TALC_00925	ENOG4105F0N	pyrophosphate phospho-hydrolase
TALC_00927	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
TALC_00929	ENOG4105BZ1	(ABC) transporter
TALC_00930	ENOG4105BZ1	(ABC) transporter
TALC_00932	ENOG4105KWI	UPF0339 protein
TALC_00943	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TALC_00944	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TALC_00947	ENOG4105E0X	reductase
TALC_00955	ENOG4105CKI	cobalamin synthesis protein
TALC_00957	ENOG41060PX	YqaJ-like viral recombinase domain
TALC_00958	ENOG4108IXY	short-chain dehydrogenase reductase
TALC_00960	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
TALC_00962	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
TALC_00964	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TALC_00966	ENOG4105C8T	Leucyl-tRNA synthetase
TALC_00969	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TALC_00970	ENOG4105CY0	Metallo-Beta-Lactamase
TALC_00971	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
TALC_00977	ENOG4105CFP	Peptidase U32
TALC_00983	ENOG4105DZS	Phenylacetate-CoA ligase
TALC_00986	ENOG4105DZS	Phenylacetate-CoA ligase
TALC_00993	ENOG41081HM	2'-5' rna ligase
TALC_00995	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
TALC_00998	ENOG4105BZU	Histidine kinase
TALC_01007	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
TALC_01016	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TALC_01017	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
TALC_01019	ENOG4105C1A	potassium transporter peripheral membrane
TALC_01020	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
TALC_01030	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TALC_01031	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TALC_01039	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
TALC_01042	ENOG4105CJ1	ABC, transporter
TALC_01045	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
TALC_01048	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TALC_01058	ENOG4105VEM	Conserved domain protein
TALC_01069	ENOG4105CAY	ferredoxin--nadp reductase
TALC_01074	ENOG4105Q9Y	Universal stress protein
TALC_01075	ENOG4105Q9Y	Universal stress protein
TALC_01076	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TALC_01077	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TALC_01079	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TALC_01080	ENOG4105VCQ	rubredoxin
TALC_01083	ENOG4108Z66	YbaK ebsC protein
TALC_01095	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TALC_01097	ENOG4105KPY	Small multidrug resistance protein
TALC_01101	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TALC_01104	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TALC_01105	ENOG4105DFM	M18 family aminopeptidase
TALC_01110	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
TALC_01114	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
TALC_01115	ENOG4105CSM	endonuclease III
TALC_01116	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TALC_01118	ENOG4105MRR	Transcriptional regulator (By similarity)
TALC_01120	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TALC_01122	ENOG410813T	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TALC_01124	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TALC_01125	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TALC_01127	ENOG4105DHP	deoxycytidine triphosphate deaminase
TALC_01130	ENOG4105CD5	CoA-binding domain protein
TALC_01136	ENOG4105EHG	Permease protein
TALC_01137	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
TALC_01138	ENOG4105BZ1	(ABC) transporter
TALC_01139	ENOG4105BZ1	(ABC) transporter
TALC_01141	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
TALC_01142	ENOG4105CTK	cobaltochelatase, cobn subunit
TALC_01146	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
TALC_01148	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
TALC_01150	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
TALC_01152	ENOG4105EET	magnesium chelatase
TALC_01157	ENOG4105CXT	aspartate transcarbamylase
TALC_01158	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
TALC_01165	ENOG4105DDK	oxidoreductase, beta subunit
TALC_01166	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TALC_01167	ENOG4105WGB	oxidoreductase, delta subunit
TALC_01168	ENOG4105EJ5	oxidoreductase gamma subunit
TALC_01172	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TALC_01173	ENOG4105EHG	Permease protein
TALC_01174	ENOG4105EHG	Permease protein
TALC_01177	ENOG4105EHG	Permease protein
TALC_01178	ENOG4105E0A	ABC, transporter
TALC_01182	ENOG4105EHG	Permease protein
TALC_01183	ENOG4105E0A	ABC, transporter
TALC_01184	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TALC_01185	ENOG4105CVJ	phosphoglycerate mutase
TALC_01189	ENOG41081F0	Precorrin-8x methylmutase
TALC_01190	ENOG4105E4R	Precorrin-3B C17-methyltransferase
TALC_01191	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
TALC_01192	ENOG4105DVK	Precorrin-2 c20-methyltransferase
TALC_01193	ENOG4105E0A	ABC, transporter
TALC_01194	ENOG4105CJ1	ABC, transporter
TALC_01196	ENOG4105CTK	cobaltochelatase, cobn subunit
TALC_01197	ENOG4105CTK	cobaltochelatase, cobn subunit
TALC_01198	ENOG4105CTK	cobaltochelatase, cobn subunit
TALC_01204	ENOG4105C22	threonyL-tRNA synthetase
TALC_01206	ENOG4105CUT	histidyl-tRNA synthetase
TALC_01207	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TALC_01208	ENOG4105D52	delta-aminolevulinic acid dehydratase
TALC_01209	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TALC_01213	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TALC_01218	ENOG4105DK7	lysyl-tRNA synthetase
TALC_01220	ENOG4108JJB	ABC transporter
TALC_01223	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
TALC_01229	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
TALC_01230	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TALC_01232	ENOG4108P62	biosynthesis protein (CbiG)
TALC_01233	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
TALC_01235	ENOG4105C4K	Nad synthetase
TALC_01240	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TALC_01249	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TALC_01250	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TALC_01254	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
TALC_01256	ENOG4107YZX	Universal stress protein
TALC_01258	ENOG4105D6E	homoserine dehydrogenase
TALC_01259	ENOG4105VUC	UPF0237 protein
TALC_01260	ENOG4105CAG	UPF0210 protein
TALC_01262	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
TALC_01269	ENOG4105CD3	dihydroorotase
TALC_01272	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
TALC_01276	ENOG41086B8	CoB-CoM heterodisulfide reductase
TALC_01287	ENOG4108Z4T	Peptidase M50
TALC_01288	ENOG4105CQB	FAD linked oxidase domain protein
TALC_01289	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TALC_01291	ENOG4105WMR	Protein CrcB homolog
TALC_01299	ENOG4105C75	arginyL-tRNA synthetase
TALC_01301	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TALC_01304	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TALC_01309	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TALC_01312	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TALC_01313	ENOG41084HQ	50S ribosomal protein L30
TALC_01314	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TALC_01318	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TALC_01319	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TALC_01320	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TALC_01324	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TALC_01325	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TALC_01328	ENOG41082SA	50s ribosomal protein l29
TALC_01329	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TALC_01332	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TALC_01333	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TALC_01335	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TALC_01339	ENOG4107QN2	dihydrolipoyl dehydrogenase
TALC_01341	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
TALC_01342	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TALC_01348	ENOG41084XV	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TALC_01349	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TALC_01350	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TALC_01351	ENOG4105C9M	aspartyl-trna synthetase
TALC_01352	ENOG4105EW9	transcriptional regulator AsnC family
TALC_01353	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TALC_01355	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
TALC_01357	ENOG4105CK7	Sodium proline symporter
TALC_01358	ENOG4105CK7	Sodium proline symporter
TALC_01360	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
TALC_01361	ENOG4105EAH	synthase
TALC_01363	ENOG4105G0J	serine threonine protein kinase
TALC_01364	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TALC_01370	ENOG4108I5C	dEAD DEAH box helicase
TALC_01377	ENOG41088T4	Helicase IV
TALC_01380	ENOG4108UJD	30S ribosomal protein S9
TALC_01381	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TALC_01382	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TALC_01384	ENOG41080HJ	6-phospho 3-hexuloisomerase
TALC_01391	ENOG4105DF6	Fe-S oxidoreductase
TALC_01392	ENOG4105QUH	Domain of unknown function (DUF2088)
TALC_01393	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TALC_01394	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TALC_01396	ENOG4105EGS	Mechanosensitive ion channel
TALC_01398	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TALC_01399	ENOG4105CFH	Aspartokinase
TALC_01400	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
TALC_01401	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
TALC_01402	ENOG4105CHM	Aminotransferase
TALC_01405	ENOG4105BZA	Phosphoglycerate kinase
TALC_01406	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TALC_01407	ENOG4105C7K	acetolactate synthase
TALC_01409	ENOG4105C7K	acetolactate synthase
TALC_01410	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
TALC_01411	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
TALC_01413	ENOG4105DC7	peptidase M24
TALC_01422	ENOG4107R37	Glutamate dehydrogenase
TALC_01425	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TALC_01430	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TALC_01431	ENOG4105C3G	gtp-binding protein
TALC_01432	ENOG4105CQ2	DNA polymerase
TALC_01433	ENOG4105CBC	glutamate synthase
TALC_01434	ENOG4105CRQ	synthase (Component I)
TALC_01435	ENOG4105DDQ	anthranilate synthase
TALC_01437	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TALC_01438	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
TALC_01440	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
TALC_01443	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TALC_01446	ENOG4105D1H	recombination factor protein RarA
TALC_01449	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TALC_01451	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TALC_01456	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TALC_01461	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
TALC_01462	ENOG4105C6T	cysteine synthase
TALC_01465	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
TALC_01467	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TALC_01468	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TALC_01470	ENOG4105E4P	ATPase (AAA
TALC_01473	ENOG4105C2C	drug resistance transporter, Bcr CflA
TALC_01476	ENOG4105DU1	integral membrane protein, terc
TALC_01478	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TALC_01479	ENOG4105CFG	Acts as a chaperone (By similarity)
TALC_01480	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TALC_01481	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TALC_01489	ENOG4105ECY	inositol monophosphatase
TALC_01498	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TALC_01503	ENOG4107U32	Beta-lactamase domain protein
TALC_01504	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
TALC_01505	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
TALC_01506	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TALC_01507	ENOG4105HDK	L-asparaginase
TALC_01508	ENOG4105HDK	L-asparaginase
TALC_01510	ENOG4105C12	Phosphoribosylglycinamide synthetase
TALC_01511	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TALC_01515	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
TALC_01521	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TALC_01524	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TALC_01525	ENOG4105N5T	Radical SAM Protein
TALC_01528	ENOG4105C3M	thioredoxin reductase
TALC_01529	ENOG4105K63	Thioredoxin
TALC_01537	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TALC_01538	ENOG4107QRT	dEAD DEAH box helicase
TALC_01539	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
TALC_01540	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TALC_01544	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TALC_01551	ENOG4107QRT	dEAD DEAH box helicase
TALC_01564	ENOG4105KPE	licD family
TALC_01566	ENOG4105D0M	Protease HtpX homolog
TALC_01572	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TALC_01574	ENOG4105CHU	acetyl-coa acetyltransferase