locus-tag	class	description
TUZN_0004	COG0529	Catalyzes the synthesis of activated sulfate
TUZN_0016	COG0297	glycogen (starch) synthase activity
TUZN_0019	COG0438	transferase activity, transferring glycosyl groups
TUZN_0022	COG1216	Glycosyl transferase, family 2
TUZN_0027	COG0714	Associated with various cellular activities
TUZN_0035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TUZN_0036	COG0531	amino acid
TUZN_0043	COG1234	tRNA 3'-trailer cleavage
TUZN_0044	COG3842	ATPase activity
TUZN_0048	COG0437	4 iron, 4 sulfur cluster binding
TUZN_0050	COG0243	molybdopterin cofactor binding
TUZN_0051	COG3301	Polysulphide reductase, NrfD
TUZN_0064	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_0067	COG0495	leucyl-tRNA aminoacylation
TUZN_0068	COG0805	protein transport
TUZN_0075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TUZN_0078	COG0494	nUDIX hydrolase
TUZN_0079	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
TUZN_0083	COG0674	pyruvate-flavodoxin oxidoreductase activity
TUZN_0083	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TUZN_0084	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_0086	COG1444	tRNA N-acetyltransferase activity
TUZN_0092	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TUZN_0097	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TUZN_0098	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TUZN_0131	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TUZN_0135	COG1802	Transcriptional regulator
TUZN_0136	COG2721	sulfolactate sulfo-lyase activity
TUZN_0137	COG2721	sulfolactate sulfo-lyase activity
TUZN_0139	COG1012	belongs to the aldehyde dehydrogenase family
TUZN_0140	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_0143	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TUZN_0144	COG0601	transmembrane transport
TUZN_0147	COG4608	Belongs to the ABC transporter superfamily
TUZN_0156	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TUZN_0158	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TUZN_0163	COG0559	Belongs to the binding-protein-dependent transport system permease family
TUZN_0165	COG1137	ATPase activity
TUZN_0166	COG0410	ABC transporter
TUZN_0169	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TUZN_0172	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TUZN_0173	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TUZN_0176	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TUZN_0181	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TUZN_0182	COG3830	Belongs to the UPF0237 family
TUZN_0183	COG2848	UPF0210 protein
TUZN_0188	COG1234	tRNA 3'-trailer cleavage
TUZN_0191	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TUZN_0204	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_0207	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TUZN_0208	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_0213	COG1960	acyl-CoA dehydrogenase activity
TUZN_0223	COG0477	Major facilitator Superfamily
TUZN_0239	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TUZN_0248	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TUZN_0250	COG1607	acyl-coa hydrolase
TUZN_0253	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TUZN_0259	COG1132	(ABC) transporter
TUZN_0260	COG2814	Major facilitator Superfamily
TUZN_0263	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TUZN_0265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TUZN_0265	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TUZN_0266	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TUZN_0268	COG0174	glutamine synthetase
TUZN_0269	COG0069	glutamate synthase activity
TUZN_0269	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TUZN_0277	COG2427	Protein of unknown function (DUF1641)
TUZN_0279	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TUZN_0279	COG0069	glutamate synthase activity
TUZN_0281	COG0017	Asparaginyl-tRNA synthetase
TUZN_0282	COG2210	Belongs to the sulfur carrier protein TusA family
TUZN_0283	COG0425	Belongs to the sulfur carrier protein TusA family
TUZN_0287	COG1489	DNA binding
TUZN_0292	COG2226	methyltransferase
TUZN_0293	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TUZN_0296	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TUZN_0297	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TUZN_0298	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TUZN_0299	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TUZN_0299	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TUZN_0316	COG0717	Belongs to the dCTP deaminase family
TUZN_0319	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TUZN_0319	COG2169	Transcriptional regulator
TUZN_0322	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TUZN_0322	COG0574	Belongs to the PEP-utilizing enzyme family
TUZN_0328	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TUZN_0339	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TUZN_0342	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TUZN_0346	COG1640	4-alpha-glucanotransferase
TUZN_0357	COG2860	membrane
TUZN_0378	COG2239	Acts as a magnesium transporter
TUZN_0390	COG1830	Aldolase
TUZN_0394	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TUZN_0399	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TUZN_0403	COG0183	Belongs to the thiolase family
TUZN_0404	COG0107	imidazoleglycerol-phosphate synthase activity
TUZN_0405	COG0131	Imidazoleglycerol-phosphate dehydratase
TUZN_0407	COG0519	Catalyzes the synthesis of GMP from XMP
TUZN_0407	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TUZN_0408	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TUZN_0413	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TUZN_0415	COG0656	L-ascorbic acid biosynthetic process
TUZN_0418	COG0556	nucleotide-excision repair
TUZN_0429	COG0277	FAD linked oxidase domain protein
TUZN_0430	COG0477	Major facilitator Superfamily
TUZN_0431	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_0433	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TUZN_0434	COG0284	orotidine-5'-phosphate decarboxylase activity
TUZN_0435	COG0540	Belongs to the ATCase OTCase family
TUZN_0442	COG0549	Belongs to the carbamate kinase family
TUZN_0443	COG0124	histidyl-tRNA synthetase
TUZN_0446	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TUZN_0450	COG2078	PFAM AMMECR1 domain protein
TUZN_0451	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TUZN_0452	COG1394	ATPase activity, coupled to movement of substances
TUZN_0457	COG0330	HflC and HflK could
TUZN_0463	COG3634	alkyl hydroperoxide reductase activity
TUZN_0465	COG2409	Drug exporters of the RND superfamily
TUZN_0467	COG1136	(ABC) transporter
TUZN_0477	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TUZN_0500	COG0419	ATPase involved in DNA repair
TUZN_0503	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TUZN_0504	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TUZN_0509	COG1620	l-lactate permease
TUZN_0510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TUZN_0511	COG0277	FAD linked oxidase domain protein
TUZN_0518	COG1720	tRNA m6t6A37 methyltransferase activity
TUZN_0524	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TUZN_0526	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TUZN_0526	COG0574	Belongs to the PEP-utilizing enzyme family
TUZN_0534	COG1914	H( )-stimulated, divalent metal cation uptake system
TUZN_0535	COG0045	succinate-CoA ligase (ADP-forming) activity
TUZN_0536	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TUZN_0537	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TUZN_0538	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TUZN_0541	COG0735	belongs to the Fur family
TUZN_0543	COG1201	RNA secondary structure unwinding
TUZN_0546	COG0037	tRNA processing
TUZN_0548	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TUZN_0556	COG0719	Fe-S assembly protein
TUZN_0558	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TUZN_0560	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
TUZN_0568	COG3842	ATPase activity
TUZN_0572	COG0667	Aldo Keto reductase
TUZN_0573	COG1201	RNA secondary structure unwinding
TUZN_0577	COG4962	Type ii secretion system protein e
TUZN_0579	COG2086	electron transfer activity
TUZN_0580	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TUZN_0581	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TUZN_0582	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TUZN_0583	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TUZN_0584	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TUZN_0586	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TUZN_0587	COG0140	phosphoribosyl-ATP diphosphatase activity
TUZN_0588	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TUZN_0597	COG0644	oxidoreductase
TUZN_0599	COG1373	ATPase (AAA superfamily
TUZN_0601	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TUZN_0611	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TUZN_0613	COG0351	phosphomethylpyrimidine kinase
TUZN_0616	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TUZN_0620	COG0017	Asparaginyl-tRNA synthetase
TUZN_0621	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TUZN_0644	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TUZN_0646	COG0308	aminopeptidase N
TUZN_0647	COG1702	phosphate starvation-inducible protein PhoH
TUZN_0648	COG1254	Belongs to the acylphosphatase family
TUZN_0651	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TUZN_0655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TUZN_0661	COG0175	sulfate reduction
TUZN_0663	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TUZN_0666	COG0017	Asparaginyl-tRNA synthetase
TUZN_0669	COG0009	L-threonylcarbamoyladenylate synthase
TUZN_0671	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TUZN_0676	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TUZN_0677	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TUZN_0689	COG0183	Belongs to the thiolase family
TUZN_0690	COG1024	Enoyl-CoA hydratase
TUZN_0692	COG0318	PFAM AMP-dependent synthetase and ligase
TUZN_0693	COG0667	Aldo Keto reductase
TUZN_0694	COG0318	PFAM AMP-dependent synthetase and ligase
TUZN_0695	COG1960	acyl-CoA dehydrogenase activity
TUZN_0696	COG0183	Belongs to the thiolase family
TUZN_0698	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TUZN_0701	COG2095	MarC family integral membrane protein
TUZN_0707	COG1271	oxidase subunit
TUZN_0712	COG2046	Belongs to the sulfate adenylyltransferase family
TUZN_0729	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TUZN_0732	COG0813	purine-nucleoside phosphorylase activity
TUZN_0735	COG0163	prenyltransferase activity
TUZN_0737	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TUZN_0738	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TUZN_0739	COG0372	Belongs to the citrate synthase family
TUZN_0741	COG0644	oxidoreductase
TUZN_0742	COG0577	efflux transmembrane transporter activity
TUZN_0745	COG1085	galactose-1-phosphate uridylyltransferase
TUZN_0746	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TUZN_0747	COG3842	ATPase activity
TUZN_0748	COG4946	Tricorn protease homolog
TUZN_0748	COG0793	Belongs to the peptidase S41A family
TUZN_0749	COG1254	Belongs to the acylphosphatase family
TUZN_0753	COG1063	alcohol dehydrogenase
TUZN_0762	COG2255	four-way junction helicase activity
TUZN_0763	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TUZN_0766	COG0419	ATPase involved in DNA repair
TUZN_0773	COG0656	L-ascorbic acid biosynthetic process
TUZN_0775	COG0393	Putative heavy-metal-binding
TUZN_0778	COG1832	CoA-binding protein
TUZN_0781	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TUZN_0782	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TUZN_0784	COG0303	'Molybdopterin
TUZN_0792	COG0083	homoserine kinase activity
TUZN_0800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TUZN_0802	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TUZN_0804	COG0505	Belongs to the CarA family
TUZN_0806	COG0165	Argininosuccinate lyase
TUZN_0807	COG0189	ligase activity
TUZN_0809	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TUZN_0811	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TUZN_0814	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TUZN_0818	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TUZN_0825	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TUZN_0826	COG0432	Pfam Uncharacterised protein family UPF0047
TUZN_0839	COG1063	alcohol dehydrogenase
TUZN_0840	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
TUZN_0842	COG1024	Enoyl-CoA hydratase
TUZN_0843	COG0154	amidase activity
TUZN_0845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TUZN_0846	COG3511	phospholipase C
TUZN_0850	COG0667	Aldo Keto reductase
TUZN_0854	COG1435	thymidine kinase activity
TUZN_0859	COG2084	Dehydrogenase
TUZN_0866	COG1131	(ABC) transporter
TUZN_0874	COG1592	Rubrerythrin
TUZN_0875	COG0434	BtpA family
TUZN_0880	COG1881	PFAM PEBP family protein
TUZN_0886	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TUZN_0889	COG2814	Major facilitator Superfamily
TUZN_0894	COG0559	Belongs to the binding-protein-dependent transport system permease family
TUZN_0897	COG0517	IMP dehydrogenase activity
TUZN_0897	COG0516	GMP reductase activity
TUZN_0910	COG0004	ammonium transporteR
TUZN_0911	COG0347	Belongs to the P(II) protein family
TUZN_0912	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TUZN_0914	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_0921	COG1716	ATPase activity
TUZN_0931	COG1716	ATPase activity
TUZN_0934	COG0515	serine threonine protein kinase
TUZN_0938	COG1960	acyl-CoA dehydrogenase activity
TUZN_0939	COG1960	acyl-CoA dehydrogenase activity
TUZN_0943	COG0517	IMP dehydrogenase activity
TUZN_0943	COG0516	GMP reductase activity
TUZN_0947	COG1053	succinate dehydrogenase
TUZN_0951	COG1012	belongs to the aldehyde dehydrogenase family
TUZN_0954	COG1968	undecaprenyl-diphosphatase activity
TUZN_0956	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TUZN_0957	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TUZN_0958	COG4948	Mandelate Racemase Muconate Lactonizing
TUZN_0960	COG1522	sequence-specific DNA binding
TUZN_0966	COG4948	Mandelate Racemase Muconate Lactonizing
TUZN_0967	COG0569	domain protein
TUZN_0971	COG0303	'Molybdopterin
TUZN_0976	COG0438	transferase activity, transferring glycosyl groups
TUZN_0983	COG1175	transmembrane transport
TUZN_0984	COG0395	ABC-type sugar transport system, permease component
TUZN_0986	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
TUZN_0988	COG0649	NAD binding
TUZN_0992	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_0993	COG0674	pyruvate-flavodoxin oxidoreductase activity
TUZN_0994	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TUZN_0995	COG1007	ATP synthesis coupled electron transport
TUZN_1001	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TUZN_1004	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TUZN_1006	COG0604	alcohol dehydrogenase
TUZN_1010	COG2217	Heavy metal translocating P-type atpase
TUZN_1015	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_1016	COG0114	fumarate hydratase activity
TUZN_1018	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
TUZN_1025	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
TUZN_1026	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TUZN_1028	COG0022	dehydrogenase e1 component
TUZN_1031	COG0321	lipoyl(octanoyl) transferase activity
TUZN_1033	COG2897	thiosulfate sulfurtransferase activity
TUZN_1037	COG1741	Belongs to the pirin family
TUZN_1042	COG1331	Highly conserved protein containing a thioredoxin domain
TUZN_1046	COG0288	reversible hydration of carbon dioxide
TUZN_1056	COG2154	pterin-4-alpha-carbinolamine dehydratase
TUZN_1060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TUZN_1065	COG0425	Belongs to the sulfur carrier protein TusA family
TUZN_1073	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TUZN_1074	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TUZN_1074	COG1845	cytochrome c oxidase, subunit III
TUZN_1076	COG1999	signal sequence binding
TUZN_1077	COG0109	protoheme IX farnesyltransferase activity
TUZN_1096	COG0778	Nitroreductase
TUZN_1098	COG2391	methyltransferase activity
TUZN_1100	COG0425	Belongs to the sulfur carrier protein TusA family
TUZN_1109	COG0446	pyridine nucleotide-disulphide oxidoreductase
TUZN_1112	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
TUZN_1116	COG0149	triose-phosphate isomerase activity
TUZN_1125	COG0312	modulator of DNA gyrase
TUZN_1127	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TUZN_1129	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TUZN_1132	COG1012	belongs to the aldehyde dehydrogenase family
TUZN_1133	COG1012	belongs to the aldehyde dehydrogenase family
TUZN_1134	COG0425	Belongs to the sulfur carrier protein TusA family
TUZN_1147	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TUZN_1163	COG0235	Class ii aldolase
TUZN_1164	COG0445	tRNA wobble uridine modification
TUZN_1167	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TUZN_1178	COG0417	DNA replication proofreading
TUZN_1180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TUZN_1183	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TUZN_1187	COG0444	Belongs to the ABC transporter superfamily
TUZN_1188	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TUZN_1189	COG0601	transmembrane transport
TUZN_1192	COG0471	metal ion transport
TUZN_1192	COG3273	potassium ion transport
TUZN_1197	COG0667	Aldo Keto reductase
TUZN_1198	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TUZN_1203	COG0411	ABC transporter
TUZN_1207	COG0437	4 iron, 4 sulfur cluster binding
TUZN_1208	COG0243	molybdopterin cofactor binding
TUZN_1211	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TUZN_1212	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TUZN_1219	COG1881	PFAM PEBP family protein
TUZN_1220	COG1122	ATPase activity
TUZN_1222	COG0535	radical SAM domain protein
TUZN_1229	COG3383	formate dehydrogenase (NAD+) activity
TUZN_1229	COG0243	molybdopterin cofactor binding
TUZN_1230	COG0437	4 iron, 4 sulfur cluster binding
TUZN_1233	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TUZN_1238	COG4172	Belongs to the ABC transporter superfamily
TUZN_1243	COG0101	tRNA pseudouridine synthase activity
TUZN_1247	COG0537	adenosine 5'-monophosphoramidase activity
TUZN_1248	COG2030	dehydratase
TUZN_1252	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TUZN_1256	COG0109	protoheme IX farnesyltransferase activity
TUZN_1259	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_1262	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TUZN_1270	COG1966	Carbon starvation protein
TUZN_1272	COG0003	Pfam Anion-transporting ATPase
TUZN_1273	COG0003	Pfam Anion-transporting ATPase
TUZN_1279	COG0477	Major facilitator Superfamily
TUZN_1280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TUZN_1285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TUZN_1286	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TUZN_1289	COG0137	argininosuccinate synthase activity
TUZN_1292	COG0473	3-isopropylmalate dehydrogenase activity
TUZN_1294	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TUZN_1295	COG0066	3-isopropylmalate dehydratase activity
TUZN_1296	COG0028	Belongs to the TPP enzyme family
TUZN_1298	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TUZN_1299	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TUZN_1302	COG2723	6-phospho-beta-galactosidase activity
TUZN_1305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TUZN_1306	COG0444	Belongs to the ABC transporter superfamily
TUZN_1307	COG4608	Belongs to the ABC transporter superfamily
TUZN_1310	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_1311	COG0302	gtp cyclohydrolase
TUZN_1312	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TUZN_1313	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TUZN_1315	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TUZN_1317	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TUZN_1319	COG4670	ketone body catabolic process
TUZN_1321	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TUZN_1323	COG1271	oxidase subunit
TUZN_1326	COG0450	alkyl hydroperoxide reductase
TUZN_1333	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TUZN_1334	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TUZN_1341	COG0251	oxidation-reduction process
TUZN_1343	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TUZN_1344	COG0051	transcription antitermination factor activity, RNA binding
TUZN_1350	COG0154	amidase activity
TUZN_1354	COG0546	phosphoglycolate phosphatase activity
TUZN_1355	COG0589	response to stress
TUZN_1363	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TUZN_1364	COG0006	proline dipeptidase activity
TUZN_1368	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TUZN_1372	COG0626	cystathionine gamma-synthase activity
TUZN_1374	COG0516	GMP reductase activity
TUZN_1374	COG0517	IMP dehydrogenase activity
TUZN_1375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TUZN_1376	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TUZN_1380	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TUZN_1394	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TUZN_1396	COG1136	(ABC) transporter
TUZN_1398	COG0577	efflux transmembrane transporter activity
TUZN_1418	COG1324	tolerance protein
TUZN_1419	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TUZN_1420	COG0456	acetyltransferase
TUZN_1424	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TUZN_1430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TUZN_1437	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TUZN_1443	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TUZN_1445	COG0517	IMP dehydrogenase activity
TUZN_1448	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TUZN_1449	COG1144	Oxidoreductase
TUZN_1450	COG0674	pyruvate-flavodoxin oxidoreductase activity
TUZN_1451	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_1461	COG0477	Major facilitator Superfamily
TUZN_1463	COG0616	signal peptide processing
TUZN_1464	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TUZN_1465	COG0527	aspartate kinase activity
TUZN_1467	COG0475	glutathione-regulated potassium exporter activity
TUZN_1468	COG0460	homoserine dehydrogenase
TUZN_1473	COG0501	Belongs to the peptidase M48B family
TUZN_1474	COG0494	nUDIX hydrolase
TUZN_1480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TUZN_1480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TUZN_1481	COG0612	Peptidase, M16
TUZN_1488	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TUZN_1489	COG0493	'glutamate synthase
TUZN_1490	COG2086	electron transfer activity
TUZN_1492	COG1110	DNA topoisomerase II activity
TUZN_1502	COG0018	arginyl-trna synthetase
TUZN_1506	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TUZN_1510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TUZN_1511	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TUZN_1517	COG1131	(ABC) transporter
TUZN_1521	COG3511	phospholipase C
TUZN_1529	COG3256	nitric oxide reductase
TUZN_1532	COG0668	transmembrane transport
TUZN_1540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TUZN_1541	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TUZN_1542	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TUZN_1552	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TUZN_1553	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TUZN_1556	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TUZN_1563	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TUZN_1566	COG0343	queuine tRNA-ribosyltransferase activity
TUZN_1572	COG0459	protein refolding
TUZN_1574	COG1047	Peptidyl-prolyl cis-trans
TUZN_1575	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TUZN_1576	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TUZN_1580	COG0417	DNA replication proofreading
TUZN_1583	COG1716	ATPase activity
TUZN_1585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TUZN_1587	COG0315	cyclic pyranopterin monophosphate synthase activity
TUZN_1588	COG0295	cytidine deaminase activity
TUZN_1590	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_1592	COG0489	protein tyrosine kinase activity
TUZN_1594	COG0052	Belongs to the universal ribosomal protein uS2 family
TUZN_1595	COG1355	regulation of microtubule-based process
TUZN_1596	COG1304	FMN binding
TUZN_1604	COG0215	cysteine-tRNA ligase activity
TUZN_1605	COG0148	phosphopyruvate hydratase activity
TUZN_1611	COG1793	dna ligase
TUZN_1615	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TUZN_1618	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TUZN_1623	COG0673	inositol 2-dehydrogenase activity
TUZN_1628	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TUZN_1635	COG0049	tRNA binding
TUZN_1636	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TUZN_1637	COG0470	DNA polymerase III
TUZN_1637	COG1067	ATP-dependent peptidase activity
TUZN_1644	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TUZN_1645	COG0512	Glutamine amidotransferase of anthranilate synthase
TUZN_1645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TUZN_1646	COG0134	indole-3-glycerol-phosphate synthase activity
TUZN_1649	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TUZN_1650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TUZN_1651	COG0446	pyridine nucleotide-disulphide oxidoreductase
TUZN_1653	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TUZN_1654	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
TUZN_1655	COG0746	molybdenum cofactor guanylyltransferase activity
TUZN_1656	COG2252	PERMEase
TUZN_1659	COG1058	Belongs to the CinA family
TUZN_1659	COG1546	Belongs to the CinA family
TUZN_1665	COG1252	NADH dehydrogenase
TUZN_1669	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
TUZN_1672	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TUZN_1674	COG0504	CTP synthase activity
TUZN_1678	COG1730	sister chromatid segregation
TUZN_1679	COG0552	protein localization to endoplasmic reticulum
TUZN_1682	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TUZN_1683	COG0081	regulation of translation
TUZN_1687	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
TUZN_1692	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TUZN_1696	COG1744	ABC transporter substrate-binding protein PnrA-like
TUZN_1706	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TUZN_1709	COG2890	protein-(glutamine-N5) methyltransferase activity
TUZN_1712	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TUZN_1720	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_1721	COG0674	pyruvate-flavodoxin oxidoreductase activity
TUZN_1726	COG1175	transmembrane transport
TUZN_1727	COG3833	ABC-type maltose transport systems, permease component
TUZN_1728	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TUZN_1733	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TUZN_1742	COG1980	fructose-bisphosphate aldolase activity
TUZN_1743	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_1744	COG1584	GPR1 FUN34 yaaH family protein
TUZN_1746	COG2095	MarC family integral membrane protein
TUZN_1749	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_1750	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TUZN_1752	COG3959	Transketolase, thiamine diphosphate binding domain
TUZN_1753	COG3958	Transketolase
TUZN_1754	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TUZN_1755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TUZN_1756	COG0436	Aminotransferase
TUZN_1757	COG0823	Involved in the tonB-independent uptake of proteins
TUZN_1757	COG4946	Tricorn protease homolog
TUZN_1757	COG1506	peptidase
TUZN_1758	COG0710	3-dehydroquinate dehydratase activity
TUZN_1759	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TUZN_1760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TUZN_1761	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TUZN_1765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TUZN_1769	COG0089	rRNA binding
TUZN_1781	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TUZN_1785	COG0459	protein refolding
TUZN_1789	COG2151	metal-sulfur cluster biosynthetic enzyme
TUZN_1790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TUZN_1793	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TUZN_1795	COG1064	alcohol dehydrogenase
TUZN_1798	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TUZN_1800	COG0483	inositol monophosphate 1-phosphatase activity
TUZN_1803	COG1078	dGTPase activity
TUZN_1818	COG1573	uracil-dna glycosylase
TUZN_1831	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TUZN_1833	COG0085	RNA polymerase activity
TUZN_1834	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TUZN_1835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TUZN_1841	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TUZN_1842	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TUZN_1845	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
TUZN_1858	COG0430	RNA-3'-phosphate cyclase activity
TUZN_1859	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TUZN_1865	COG0012	GTP binding
TUZN_1867	COG0528	UMP kinase activity
TUZN_1875	COG2271	Major facilitator Superfamily
TUZN_1890	COG0189	ligase activity
TUZN_1891	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TUZN_1903	COG0303	'Molybdopterin
TUZN_1904	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TUZN_1906	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TUZN_1907	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TUZN_1908	COG1234	tRNA 3'-trailer cleavage
TUZN_1915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TUZN_1925	COG0585	pseudouridine synthase activity
TUZN_1927	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TUZN_1928	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TUZN_1938	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TUZN_1941	COG0010	Belongs to the arginase family
TUZN_1942	COG0423	glycine-tRNA ligase activity
TUZN_1945	COG0071	Belongs to the small heat shock protein (HSP20) family
TUZN_1947	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TUZN_1957	COG0456	acetyltransferase
TUZN_1957	COG0454	-acetyltransferase
TUZN_1973	COG1446	asparaginase
TUZN_1974	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TUZN_1977	COG0181	hydroxymethylbilane synthase activity
TUZN_1978	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TUZN_1979	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TUZN_1980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TUZN_1982	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TUZN_1982	COG1648	precorrin-2 dehydrogenase activity
TUZN_1983	COG0113	porphobilinogen synthase activity
TUZN_1984	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TUZN_1985	COG0255	Belongs to the universal ribosomal protein uL29 family
TUZN_1989	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TUZN_1990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TUZN_1992	COG0247	lactate metabolic process
TUZN_1992	COG2181	nitrate reductase activity
TUZN_1993	COG1215	transferase activity, transferring glycosyl groups
TUZN_1994	COG1260	myo-inositol-1-phosphate synthase
TUZN_1996	COG0501	Belongs to the peptidase M48B family
TUZN_1998	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TUZN_1999	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TUZN_2002	COG0126	phosphoglycerate kinase activity
TUZN_2003	COG1748	Saccharopine dehydrogenase
TUZN_2004	COG0589	response to stress
TUZN_2007	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TUZN_2008	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TUZN_2010	COG0072	phenylalanine-tRNA ligase activity
TUZN_2018	COG0371	Dehydrogenase
TUZN_2021	COG0281	malic enzyme
TUZN_2023	COG0372	Belongs to the citrate synthase family
TUZN_2025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TUZN_2039	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
TUZN_2040	COG2079	MmgE PrpD family protein
TUZN_2041	COG0538	isocitrate dehydrogenase activity
TUZN_2046	COG0492	ferredoxin-NADP+ reductase activity
TUZN_2047	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TUZN_2061	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TUZN_2063	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TUZN_2072	COG0477	Major facilitator Superfamily
TUZN_2080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TUZN_2081	COG1024	Enoyl-CoA hydratase
TUZN_2082	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TUZN_2087	COG0730	response to heat
TUZN_2094	COG0297	glycogen (starch) synthase activity
TUZN_2096	COG0159	tryptophan synthase activity
TUZN_2098	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TUZN_2099	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TUZN_2102	COG1335	isochorismatase
TUZN_2103	COG4555	ABC transporter
TUZN_2108	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TUZN_2111	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TUZN_2115	COG0200	Binds to the 23S rRNA
TUZN_2122	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TUZN_2123	COG1201	RNA secondary structure unwinding
TUZN_2126	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TUZN_2127	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TUZN_2130	COG0039	L-malate dehydrogenase activity
TUZN_2139	COG0714	Associated with various cellular activities
TUZN_2143	COG2301	Belongs to the HpcH HpaI aldolase family
TUZN_2145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_2146	COG0477	Major facilitator Superfamily
TUZN_2158	COG2414	aldehyde ferredoxin oxidoreductase
TUZN_2164	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TUZN_2165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TUZN_2167	COG0477	Major facilitator Superfamily
TUZN_2168	COG0477	Major facilitator Superfamily
TUZN_2173	COG1007	ATP synthesis coupled electron transport
TUZN_2175	COG0651	ATP synthesis coupled electron transport
TUZN_2180	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TUZN_2186	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TUZN_2186	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TUZN_2188	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TUZN_2190	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
TUZN_2191	COG0409	Hydrogenase expression formation protein
TUZN_2196	COG0157	Belongs to the NadC ModD family
TUZN_2199	COG0310	cobalt ion transport
TUZN_2202	COG1122	ATPase activity
TUZN_2213	COG0864	Transcriptional regulator
TUZN_2214	COG0375	protein maturation
TUZN_2215	COG0489	protein tyrosine kinase activity
TUZN_2216	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_2218	COG0309	Hydrogenase expression formation protein (HypE)
TUZN_2219	COG2220	Zn-dependent hydrolases of the beta-lactamase fold