locus-tag	class	description
THA_100	COG1530	ribonuclease E activity
THA_1000	COG1595	DNA-templated transcription, initiation
THA_1003	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THA_1004	COG5002	protein histidine kinase activity
THA_1004	COG5001	Diguanylate cyclase
THA_1004	COG3447	MASE1 domain protein
THA_1007	COG0366	Alpha amylase catalytic
THA_1008	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
THA_1009	COG3290	protein histidine kinase activity
THA_1009	COG0840	transmembrane signaling receptor activity
THA_101	COG0572	uridine kinase
THA_1014	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
THA_1016	COG0840	transmembrane signaling receptor activity
THA_1017	COG4608	Belongs to the ABC transporter superfamily
THA_1018	COG0444	Belongs to the ABC transporter superfamily
THA_1019	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THA_1021	COG0747	negative chemotaxis
THA_1024	COG0384	phenazine biosynthesis protein PhzF
THA_1025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THA_1027	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THA_104	COG1923	regulation of RNA biosynthetic process
THA_1040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THA_1042	COG1492	cobalamin metabolic process
THA_1043	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
THA_1046	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
THA_1049	COG2199	diguanylate cyclase activity
THA_105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
THA_1053	COG3345	alpha-galactosidase
THA_1054	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
THA_1059	COG1472	Belongs to the glycosyl hydrolase 3 family
THA_1061	COG1175	transmembrane transport
THA_1062	COG0395	ABC-type sugar transport system, permease component
THA_1065	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
THA_1068	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
THA_1069	COG2241	protein methyltransferase activity
THA_1070	COG2264	protein methyltransferase activity
THA_1076	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
THA_1077	COG0181	hydroxymethylbilane synthase activity
THA_1079	COG0113	porphobilinogen synthase activity
THA_108	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
THA_1081	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
THA_1082	COG0310	cobalt ion transport
THA_109	COG0268	Binds directly to 16S ribosomal RNA
THA_1090	COG0519	Catalyzes the synthesis of GMP from XMP
THA_1090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
THA_1091	COG1704	LemA family
THA_1093	COG0778	Nitroreductase
THA_1094	COG0646	methionine synthase
THA_1094	COG1410	methionine synthase
THA_1096	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
THA_1099	COG0460	homoserine dehydrogenase
THA_1099	COG0527	aspartate kinase activity
THA_1105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
THA_1106	COG2235	arginine
THA_1109	COG5001	Diguanylate cyclase
THA_1110	COG0840	transmembrane signaling receptor activity
THA_1114	COG0561	phosphatase activity
THA_1116	COG0124	histidyl-tRNA synthetase
THA_1118	COG1757	Na H antiporter
THA_1121	COG1131	(ABC) transporter
THA_1124	COG1187	pseudouridine synthase activity
THA_1125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
THA_1127	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
THA_1128	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
THA_1133	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
THA_1136	COG2819	hydrolase of the alpha beta superfamily
THA_114	COG1110	DNA topoisomerase II activity
THA_1141	COG0628	permease
THA_1147	COG1196	nuclear chromosome segregation
THA_1148	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
THA_1149	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
THA_115	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
THA_1150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THA_1164	COG5012	cobalamin binding
THA_1165	COG0084	hydrolase, TatD family'
THA_1166	COG0632	four-way junction helicase activity
THA_1171	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
THA_1173	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
THA_1175	COG0154	amidase activity
THA_1176	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THA_1178	COG0635	Involved in the biosynthesis of porphyrin-containing compound
THA_1179	COG0772	Belongs to the SEDS family
THA_118	COG5002	protein histidine kinase activity
THA_1181	COG0714	Associated with various cellular activities
THA_1184	COG1164	Oligoendopeptidase f
THA_1186	COG0101	tRNA pseudouridine synthase activity
THA_1188	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
THA_119	COG0745	RESPONSE REGULATOR receiver
THA_1190	COG2198	Histidine kinase
THA_1190	COG0643	Histidine kinase
THA_1191	COG0835	chemotaxis
THA_1192	COG2201	protein-glutamate methylesterase activity
THA_1194	COG1338	Plays a role in the flagellum-specific transport system
THA_1195	COG1987	bacterial-type flagellum assembly
THA_1196	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
THA_1197	COG0052	Belongs to the universal ribosomal protein uS2 family
THA_1198	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
THA_1199	COG0291	Belongs to the bacterial ribosomal protein bL35 family
THA_120	COG0704	Plays a role in the regulation of phosphate uptake
THA_1200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
THA_1204	COG0469	pyruvate kinase activity
THA_1207	COG0564	pseudouridine synthase activity
THA_121	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
THA_1210	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
THA_1211	COG0049	tRNA binding
THA_1212	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THA_1213	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
THA_1214	COG0051	transcription antitermination factor activity, RNA binding
THA_1215	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
THA_1216	COG0088	Forms part of the polypeptide exit tunnel
THA_1217	COG0089	rRNA binding
THA_1218	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THA_1219	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
THA_122	COG0573	inorganic phosphate transmembrane transporter activity
THA_1220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
THA_1221	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
THA_1222	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
THA_1223	COG0255	Belongs to the universal ribosomal protein uL29 family
THA_1224	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
THA_1225	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
THA_1226	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
THA_1227	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
THA_1228	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
THA_1229	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
THA_123	COG0581	inorganic phosphate transmembrane transporter activity
THA_1230	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
THA_1231	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
THA_1232	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
THA_1233	COG1841	ribosomal large subunit assembly
THA_1234	COG0200	Binds to the 23S rRNA
THA_1235	COG0201	protein transport
THA_1236	COG0563	adenylate kinase activity
THA_1238	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
THA_1239	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THA_1240	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
THA_1241	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
THA_1242	COG0202	RNA polymerase activity
THA_1243	COG0203	ribosomal protein L17
THA_1244	COG0544	peptidyl-prolyl cis-trans isomerase activity
THA_1245	COG0740	serine-type endopeptidase activity
THA_1246	COG0217	transcriptional regulatory protein
THA_1248	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
THA_1249	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
THA_125	COG1012	belongs to the aldehyde dehydrogenase family
THA_1250	COG0564	pseudouridine synthase activity
THA_1251	COG0174	glutamine synthetase
THA_1252	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THA_1253	COG1518	maintenance of DNA repeat elements
THA_1262	COG2342	PFAM TM1410 hypothetical-related protein
THA_1266	COG0438	transferase activity, transferring glycosyl groups
THA_127	COG1846	Transcriptional regulator
THA_1274	COG1214	PFAM Peptidase M22, glycoprotease
THA_1275	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
THA_1280	COG2078	PFAM AMMECR1 domain protein
THA_1285	COG0037	tRNA processing
THA_1286	COG3681	Belongs to the UPF0597 family
THA_1288	COG1070	Carbohydrate kinase
THA_1289	COG1509	lysine 2,3-aminomutase activity
THA_129	COG1105	Belongs to the carbohydrate kinase PfkB family
THA_1291	COG1609	Transcriptional regulator
THA_1292	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
THA_1293	COG0395	ABC-type sugar transport system, permease component
THA_1294	COG1175	transmembrane transport
THA_130	COG1028	Short-chain dehydrogenase reductase Sdr
THA_1304	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
THA_1305	COG3481	metal-dependent phosphohydrolase, HD sub domain
THA_1306	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
THA_1307	COG0227	Belongs to the bacterial ribosomal protein bL28 family
THA_1309	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
THA_1310	COG0358	DNA primase activity
THA_1311	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
THA_1312	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
THA_1313	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
THA_1314	COG0211	Belongs to the bacterial ribosomal protein bL27 family
THA_1316	COG0261	This protein binds to 23S rRNA in the presence of protein L20
THA_1318	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
THA_1319	COG2176	DNA-directed DNA polymerase activity
THA_132	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
THA_1320	COG2359	stage V sporulation protein S
THA_1322	COG3872	metal-dependent enzyme
THA_1323	COG1131	(ABC) transporter
THA_1324	COG0784	Response regulator, receiver
THA_1324	COG3437	response regulator, receiver
THA_1325	COG0019	diaminopimelate decarboxylase activity
THA_1326	COG1473	amidohydrolase
THA_1327	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
THA_1328	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
THA_1329	COG0012	GTP binding
THA_1330	COG2052	Domain of unknown function (DUF370)
THA_1331	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THA_1332	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THA_1335	COG0546	phosphoglycolate phosphatase activity
THA_1337	COG0784	Response regulator, receiver
THA_1337	COG3437	response regulator, receiver
THA_1338	COG5002	protein histidine kinase activity
THA_134	COG0745	RESPONSE REGULATOR receiver
THA_1340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
THA_1341	COG0438	transferase activity, transferring glycosyl groups
THA_1342	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THA_1344	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
THA_1345	COG0085	RNA polymerase activity
THA_1346	COG0222	ribosome binding
THA_1347	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
THA_135	COG5002	protein histidine kinase activity
THA_1351	COG0463	Glycosyl transferase, family 2
THA_1351	COG0457	Tetratricopeptide repeat
THA_1352	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
THA_1353	COG0305	Participates in initiation and elongation during chromosome replication
THA_1355	COG0251	oxidation-reduction process
THA_1357	COG2211	Major facilitator Superfamily
THA_1359	COG0561	phosphatase activity
THA_1362	COG0017	Asparaginyl-tRNA synthetase
THA_1363	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
THA_1366	COG1469	GTP cyclohydrolase I activity
THA_1370	COG1131	(ABC) transporter
THA_1374	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
THA_1378	COG1376	ErfK ybiS ycfS ynhG family protein
THA_138	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
THA_1382	COG0785	Cytochrome C biogenesis protein
THA_139	COG0166	Belongs to the GPI family
THA_1390	COG1516	flagellar protein fliS
THA_1393	COG4608	Belongs to the ABC transporter superfamily
THA_1394	COG0444	Belongs to the ABC transporter superfamily
THA_1396	COG0601	transmembrane transport
THA_1398	COG0742	ribosomal rna small subunit methyltransferase
THA_1399	COG1177	transmembrane transport
THA_14	COG2801	Transposase and inactivated derivatives
THA_1400	COG1176	ABC-type spermidine putrescine transport system, permease component I
THA_1401	COG3842	ATPase activity
THA_1402	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
THA_1403	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THA_1404	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
THA_1406	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THA_1408	COG1811	Na channel or pump
THA_1410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
THA_1411	COG1480	7TM receptor with intracellular HD hydrolase
THA_1412	COG1702	phosphate starvation-inducible protein PhoH
THA_1414	COG1703	isobutyryl-CoA mutase activity
THA_1415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THA_1416	COG4770	biotin carboxylase activity
THA_142	COG2199	diguanylate cyclase activity
THA_1422	COG0653	protein targeting
THA_1423	COG0850	regulation of cytokinetic process
THA_1427	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
THA_1429	COG1815	bacterial-type flagellum-dependent cell motility
THA_143	COG0556	nucleotide-excision repair
THA_1431	COG1677	Flagellar hook-basal body complex protein FliE
THA_1433	COG0443	Heat shock 70 kDa protein
THA_1434	COG0393	Putative heavy-metal-binding
THA_1435	COG1073	alpha beta
THA_1439	COG1725	Transcriptional regulator
THA_1440	COG0183	Belongs to the thiolase family
THA_1442	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
THA_1443	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
THA_1443	COG0493	'glutamate synthase
THA_1444	COG0543	2 iron, 2 sulfur cluster binding
THA_1445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THA_1446	COG1940	carbohydrate kinase activity
THA_1451	COG2201	protein-glutamate methylesterase activity
THA_1459	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THA_1460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
THA_1461	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
THA_1462	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
THA_1464	COG1418	mRNA catabolic process
THA_1466	COG1739	Uncharacterized protein family UPF0029
THA_1467	COG0622	Phosphoesterase
THA_1468	COG2313	pseudouridylate synthase activity
THA_1470	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
THA_1471	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
THA_1472	COG0047	phosphoribosylformylglycinamidine synthase activity
THA_1473	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
THA_1474	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
THA_1475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
THA_1476	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
THA_1477	COG1045	serine acetyltransferase
THA_1478	COG0039	L-malate dehydrogenase activity
THA_1488	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
THA_1489	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
THA_149	COG1323	Belongs to the UPF0348 family
THA_1490	COG1073	alpha beta
THA_1492	COG2203	Gaf domain
THA_1492	COG2199	diguanylate cyclase activity
THA_1493	COG0584	glycerophosphoryl diester phosphodiesterase
THA_1494	COG0156	8-amino-7-oxononanoate synthase activity
THA_1495	COG1063	alcohol dehydrogenase
THA_1499	COG0534	Mate efflux family protein
THA_150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
THA_1505	COG1027	Aspartate ammonia-lyase
THA_1510	COG0572	uridine kinase
THA_1511	COG1078	dGTPase activity
THA_1512	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
THA_1517	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
THA_1518	COG1660	Displays ATPase and GTPase activities
THA_1519	COG0391	Required for morphogenesis under gluconeogenic growth conditions
THA_152	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
THA_1521	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
THA_1522	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
THA_1523	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
THA_1525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
THA_1527	COG1132	(ABC) transporter
THA_1529	COG0444	Belongs to the ABC transporter superfamily
THA_153	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
THA_1530	COG4608	Belongs to the ABC transporter superfamily
THA_1531	COG0747	negative chemotaxis
THA_1532	COG0601	transmembrane transport
THA_1533	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THA_154	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
THA_1546	COG0640	Transcriptional regulator
THA_1547	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
THA_1548	COG3842	ATPase activity
THA_155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THA_155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THA_1551	COG1309	transcriptional regulator
THA_1552	COG0254	rRNA binding
THA_1555	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
THA_156	COG0235	Class ii aldolase
THA_1561	COG0483	inositol monophosphate 1-phosphatase activity
THA_1563	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THA_1565	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
THA_1567	COG1610	YqeY-like protein
THA_1568	COG0698	ribose 5-phosphate isomerase
THA_1569	COG1366	Belongs to the anti-sigma-factor antagonist family
THA_1570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
THA_1572	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
THA_1573	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THA_1573	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THA_1578	COG3250	beta-galactosidase activity
THA_158	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
THA_1580	COG1085	galactose-1-phosphate uridylyltransferase
THA_1581	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
THA_1582	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
THA_1582	COG0540	Belongs to the ATCase OTCase family
THA_1584	COG0735	belongs to the Fur family
THA_1585	COG0450	alkyl hydroperoxide reductase
THA_1586	COG1773	rubredoxin
THA_1590	COG2033	superoxide reductase activity
THA_1592	COG4964	Belongs to the GSP D family
THA_160	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
THA_1600	COG0720	synthase
THA_1604	COG0745	RESPONSE REGULATOR receiver
THA_1605	COG0126	phosphoglycerate kinase activity
THA_1605	COG0149	triose-phosphate isomerase activity
THA_1606	COG0126	phosphoglycerate kinase activity
THA_1607	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
THA_1610	COG1157	protein secretion by the type III secretion system
THA_1612	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
THA_1613	COG0191	fructose-bisphosphate aldolase activity
THA_1616	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
THA_1619	COG0233	cytoplasmic translational termination
THA_162	COG0840	transmembrane signaling receptor activity
THA_1620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
THA_1621	COG0575	Belongs to the CDS family
THA_1622	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
THA_1623	COG1077	Cell shape determining protein MreB Mrl
THA_1626	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
THA_1630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THA_1633	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
THA_1634	COG1749	Flagellar hook protein flgE
THA_1635	COG1582	Flagellar protein (FlbD)
THA_1637	COG1360	Flagellar Motor Protein
THA_1639	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THA_1640	COG1776	CheC inhibitor of MCP methylation
THA_1640	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THA_1642	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
THA_1644	COG2239	Acts as a magnesium transporter
THA_1646	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
THA_1647	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
THA_1648	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
THA_1650	COG1120	ATPase activity
THA_1653	COG2172	sigma factor antagonist activity
THA_1654	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
THA_1655	COG1490	D-aminoacyl-tRNA deacylase activity
THA_1656	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
THA_1660	COG2080	2 iron, 2 sulfur cluster binding
THA_1660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
THA_1661	COG2080	2 iron, 2 sulfur cluster binding
THA_1665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
THA_1668	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
THA_1673	COG3314	Sporulation integral membrane protein YlbJ
THA_1674	COG0019	diaminopimelate decarboxylase activity
THA_1677	COG0357	Ribosomal RNA small subunit methyltransferase G
THA_1678	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
THA_1683	COG0493	'glutamate synthase
THA_1684	COG0649	NAD binding
THA_1685	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THA_1686	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THA_1687	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
THA_1689	COG0651	ATP synthesis coupled electron transport
THA_169	COG0569	domain protein
THA_169	COG2985	domain, Protein
THA_1691	COG1006	Multisubunit Na H antiporter MnhC subunit
THA_1692	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
THA_1692	COG2111	Na H antiporter
THA_1695	COG2212	antiporter activity
THA_1696	COG1863	multisubunit Na H antiporter MnhE subunit
THA_1697	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
THA_1699	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
THA_170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
THA_1701	COG0737	Belongs to the 5'-nucleotidase family
THA_1702	COG1435	thymidine kinase activity
THA_1703	COG2770	Histidine kinase
THA_1703	COG3437	response regulator, receiver
THA_1709	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
THA_171	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
THA_1710	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
THA_1711	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
THA_1713	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
THA_1714	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
THA_1717	COG1752	Esterase of the alpha-beta hydrolase superfamily
THA_1718	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
THA_172	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
THA_1720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THA_1720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THA_1724	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
THA_1725	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
THA_1726	COG0658	competence protein
THA_1727	COG0195	Participates in both transcription termination and antitermination
THA_1728	COG0779	Required for maturation of 30S ribosomal subunits
THA_173	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
THA_1733	COG0343	queuine tRNA-ribosyltransferase activity
THA_1736	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THA_1737	COG2151	metal-sulfur cluster biosynthetic enzyme
THA_1738	COG2890	protein-(glutamine-N5) methyltransferase activity
THA_1739	COG0359	binds to the 23S rRNA
THA_174	COG2171	N-acyltransferase activity
THA_1742	COG0617	tRNA 3'-terminal CCA addition
THA_1749	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
THA_1750	COG1776	CheC inhibitor of MCP methylation
THA_1753	COG0455	bacterial-type flagellum organization
THA_1754	COG1419	protein localization to endoplasmic reticulum
THA_1755	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THA_176	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
THA_1764	COG0628	permease
THA_1765	COG3956	TIGRFAM MazG family protein
THA_1766	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
THA_1768	COG2738	Putative neutral zinc metallopeptidase
THA_1770	COG0557	exoribonuclease II activity
THA_1772	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THA_1774	COG0497	DNA recombination
THA_1775	COG0295	cytidine deaminase activity
THA_1777	COG1032	radical SAM domain protein
THA_1778	COG1162	GTPase activity
THA_178	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
THA_1780	COG0820	rRNA (adenine-C2-)-methyltransferase activity
THA_1781	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
THA_1783	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
THA_1784	COG1639	'signal transduction protein
THA_1785	COG5002	protein histidine kinase activity
THA_1787	COG0218	Necessary for normal cell division and for the maintenance of normal septation
THA_1788	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
THA_1789	COG0802	atpase or kinase
THA_179	COG0815	Transfers the fatty acyl group on membrane lipoproteins
THA_1791	COG1774	PSP1 C-terminal conserved region
THA_1792	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
THA_1793	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
THA_1795	COG1268	BioY protein
THA_1796	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
THA_1798	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
THA_1799	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
THA_1801	COG0351	phosphomethylpyrimidine kinase
THA_1801	COG1992	Thiamine-phosphate synthase
THA_1802	COG0205	6-phosphofructokinase activity
THA_1803	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
THA_1804	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
THA_181	COG0404	The glycine cleavage system catalyzes the degradation of glycine
THA_1811	COG0571	ribonuclease III activity
THA_1812	COG0519	Catalyzes the synthesis of GMP from XMP
THA_1812	COG0518	GMP synthase (glutamine-hydrolyzing) activity
THA_1813	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
THA_1813	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
THA_1814	COG0728	peptidoglycan biosynthetic process
THA_1816	COG0758	DNA mediated transformation
THA_1817	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
THA_1819	COG1185	polyribonucleotide nucleotidyltransferase activity
THA_182	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THA_1820	COG0612	Peptidase, M16
THA_1822	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
THA_1823	COG1175	transmembrane transport
THA_1824	COG0395	ABC-type sugar transport system, permease component
THA_1825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
THA_1826	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
THA_1827	COG1366	Belongs to the anti-sigma-factor antagonist family
THA_1828	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
THA_1829	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
THA_1829	COG0539	negative regulation of cytoplasmic translation
THA_183	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THA_1830	COG1160	GTP binding
THA_1831	COG1744	ABC transporter substrate-binding protein PnrA-like
THA_1834	COG0230	Belongs to the bacterial ribosomal protein bL34 family
THA_1835	COG0594	ribonuclease P activity
THA_1836	COG0706	membrane insertase activity
THA_184	COG1454	alcohol dehydrogenase
THA_1841	COG0174	glutamine synthetase
THA_1842	COG2199	diguanylate cyclase activity
THA_1842	COG2203	Gaf domain
THA_1844	COG0514	ATP-dependent DNA helicase (RecQ)
THA_1847	COG1132	(ABC) transporter
THA_185	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
THA_1857	COG0587	DNA-directed DNA polymerase activity
THA_1858	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
THA_1859	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
THA_1860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THA_1861	COG3706	GGDEF domain
THA_1862	COG0812	UDP-N-acetylmuramate dehydrogenase activity
THA_1863	COG1362	aminopeptidase activity
THA_1868	COG1482	cell wall glycoprotein biosynthetic process
THA_187	COG0494	nUDIX hydrolase
THA_1870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
THA_1871	COG2255	four-way junction helicase activity
THA_1872	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
THA_1874	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
THA_1875	COG0704	Plays a role in the regulation of phosphate uptake
THA_1877	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
THA_1878	COG0138	bifunctional purine biosynthesis protein purh
THA_188	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
THA_1882	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
THA_1883	COG2894	cell division
THA_1888	COG0552	protein localization to endoplasmic reticulum
THA_189	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
THA_1890	COG1388	LysM domain
THA_1890	COG3584	3D domain protein
THA_1892	COG0482	sulfurtransferase activity
THA_1893	COG0037	tRNA processing
THA_1893	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
THA_1894	COG1316	TRANSCRIPTIONal
THA_1895	COG1515	deoxyribonuclease V activity
THA_1897	COG1242	4 iron, 4 sulfur cluster binding
THA_1898	COG0402	S-adenosylhomocysteine deaminase activity
THA_1899	COG0799	negative regulation of ribosome biogenesis
THA_190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THA_190	COG0674	pyruvate-flavodoxin oxidoreductase activity
THA_1900	COG0285	dihydrofolate synthase activity
THA_1901	COG0525	valine-tRNA ligase activity
THA_1903	COG4656	Part of a membrane complex involved in electron transport
THA_1904	COG4658	electron transport chain
THA_1906	COG4660	Part of a membrane complex involved in electron transport
THA_1907	COG4657	Part of a membrane complex involved in electron transport
THA_1912	COG0517	IMP dehydrogenase activity
THA_1912	COG0516	GMP reductase activity
THA_1914	COG1028	Short-chain dehydrogenase reductase Sdr
THA_1915	COG0366	Alpha amylase catalytic
THA_1916	COG2226	methyltransferase
THA_1918	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
THA_1919	COG1151	hydroxylamine reductase activity
THA_192	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
THA_1921	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
THA_1922	COG0157	Belongs to the NadC ModD family
THA_1924	COG3706	GGDEF domain
THA_1926	COG2723	6-phospho-beta-galactosidase activity
THA_1927	COG0730	response to heat
THA_1929	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
THA_1932	COG1175	transmembrane transport
THA_1937	COG0395	ABC-type sugar transport system, permease component
THA_194	COG1122	ATPase activity
THA_1940	COG4989	oxidoreductase activity
THA_1944	COG4948	Mandelate Racemase Muconate Lactonizing
THA_1946	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THA_1947	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
THA_1948	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
THA_1954	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THA_1955	COG1518	maintenance of DNA repeat elements
THA_196	COG0205	6-phosphofructokinase activity
THA_1962	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
THA_1966	COG1609	Transcriptional regulator
THA_1967	COG1175	transmembrane transport
THA_1968	COG0395	ABC-type sugar transport system, permease component
THA_1970	COG1486	melibiose metabolic process
THA_1972	COG1028	Short-chain dehydrogenase reductase Sdr
THA_1974	COG0798	PFAM Bile acid sodium symporter
THA_1976	COG0300	oxidoreductase activity
THA_1978	COG1013	pyruvate-flavodoxin oxidoreductase activity
THA_198	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THA_1988	COG3842	ATPase activity
THA_1989	COG0438	transferase activity, transferring glycosyl groups
THA_199	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THA_1990	COG1737	Transcriptional regulator
THA_1994	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
THA_20	COG0730	response to heat
THA_200	COG1862	Preprotein translocase
THA_2000	COG2189	Belongs to the N(4) N(6)-methyltransferase family
THA_2001	COG3547	Transposase (IS116 IS110 IS902 family)
THA_2007	COG2801	Transposase and inactivated derivatives
THA_201	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
THA_2012	COG2801	Transposase and inactivated derivatives
THA_2016	COG2801	Transposase and inactivated derivatives
THA_2017	COG3547	Transposase (IS116 IS110 IS902 family)
THA_2018	COG2801	Transposase and inactivated derivatives
THA_2019	COG3547	Transposase (IS116 IS110 IS902 family)
THA_2022	COG2801	Transposase and inactivated derivatives
THA_2024	COG3547	Transposase (IS116 IS110 IS902 family)
THA_203	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
THA_2031	COG2801	Transposase and inactivated derivatives
THA_2033	COG2801	Transposase and inactivated derivatives
THA_2038	COG3547	Transposase (IS116 IS110 IS902 family)
THA_204	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
THA_2040	COG2801	Transposase and inactivated derivatives
THA_2041	COG3547	Transposase (IS116 IS110 IS902 family)
THA_2042	COG3547	Transposase (IS116 IS110 IS902 family)
THA_207	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
THA_211	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THA_211	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THA_214	COG1193	negative regulation of DNA recombination
THA_216	COG0306	phosphate transporter
THA_22	COG0768	penicillin binding
THA_220	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
THA_222	COG0280	phosphate acetyltransferase
THA_224	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
THA_225	COG1141	Ferredoxin
THA_227	COG1744	ABC transporter substrate-binding protein PnrA-like
THA_234	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
THA_235	COG1307	EDD domain protein, DegV family
THA_236	COG1307	EDD domain protein, DegV family
THA_237	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
THA_238	COG0542	response to heat
THA_24	COG0275	rRNA processing
THA_247	COG0492	ferredoxin-NADP+ reductase activity
THA_248	COG1335	isochorismatase
THA_249	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
THA_250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
THA_252	COG1564	THIamine pyrophosphokinase
THA_253	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
THA_254	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
THA_255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
THA_256	COG0546	phosphoglycolate phosphatase activity
THA_257	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
THA_259	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
THA_260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
THA_260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
THA_261	COG0307	riboflavin synthase, alpha
THA_262	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THA_262	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THA_264	COG0822	iron-sulfur transferase activity
THA_265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
THA_266	COG0719	Fe-S assembly protein
THA_267	COG0719	Fe-S assembly protein
THA_269	COG0459	protein refolding
THA_270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
THA_272	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
THA_274	COG0312	modulator of DNA gyrase
THA_275	COG0312	modulator of DNA gyrase
THA_276	COG3457	Alanine racemase
THA_278	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
THA_279	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
THA_28	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
THA_280	COG0442	prolyl-tRNA aminoacylation
THA_281	COG0215	cysteine-tRNA ligase activity
THA_282	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THA_283	COG2233	PERMEase
THA_288	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THA_289	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
THA_290	COG1335	isochorismatase
THA_291	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
THA_294	COG0297	glycogen (starch) synthase activity
THA_296	COG3829	transcription factor binding
THA_296	COG3290	protein histidine kinase activity
THA_297	COG0432	Pfam Uncharacterised protein family UPF0047
THA_298	COG1181	Belongs to the D-alanine--D-alanine ligase family
THA_30	COG4608	Belongs to the ABC transporter superfamily
THA_301	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THA_302	COG2379	hydroxypyruvate reductase
THA_303	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THA_304	COG0484	heat shock protein binding
THA_305	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THA_307	COG0477	Major facilitator Superfamily
THA_308	COG1827	regulation of RNA biosynthetic process
THA_31	COG0444	Belongs to the ABC transporter superfamily
THA_321	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THA_322	COG1518	maintenance of DNA repeat elements
THA_323	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THA_325	COG1047	Peptidyl-prolyl cis-trans
THA_328	COG1363	Peptidase, m42
THA_33	COG0601	transmembrane transport
THA_330	COG1758	RNA polymerase activity
THA_331	COG0194	GDP metabolic process
THA_332	COG2052	Domain of unknown function (DUF370)
THA_337	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THA_339	COG3426	butyrate kinase activity
THA_34	COG0322	excinuclease ABC activity
THA_340	COG0280	phosphate acetyltransferase
THA_341	COG3426	butyrate kinase activity
THA_342	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
THA_344	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
THA_345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THA_347	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
THA_348	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
THA_351	COG0167	dihydroorotate dehydrogenase activity
THA_357	COG2359	stage V sporulation protein S
THA_358	COG0737	Belongs to the 5'-nucleotidase family
THA_359	COG1132	(ABC) transporter
THA_36	COG0509	glycine decarboxylation via glycine cleavage system
THA_365	COG0301	tRNA thio-modification
THA_366	COG0672	)-iron permease
THA_369	COG2217	Heavy metal translocating P-type atpase
THA_370	COG1937	Protein conserved in bacteria
THA_371	COG1132	(ABC) transporter
THA_38	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
THA_38	COG1918	ferrous iron import across plasma membrane
THA_380	COG1164	Oligoendopeptidase f
THA_381	COG0534	Mate efflux family protein
THA_383	COG0667	Aldo Keto reductase
THA_386	COG1131	(ABC) transporter
THA_388	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
THA_388	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
THA_389	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
THA_389	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
THA_392	COG1573	uracil-dna glycosylase
THA_393	COG0574	Belongs to the PEP-utilizing enzyme family
THA_393	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
THA_395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
THA_396	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
THA_397	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
THA_398	COG0193	aminoacyl-tRNA hydrolase activity
THA_4	COG0513	Belongs to the DEAD box helicase family
THA_402	COG0529	Catalyzes the synthesis of activated sulfate
THA_403	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
THA_404	COG4974	Belongs to the 'phage' integrase family
THA_405	COG0148	phosphopyruvate hydratase activity
THA_407	COG0497	DNA recombination
THA_408	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
THA_41	COG1555	photosystem II stabilization
THA_41	COG1596	polysaccharide export
THA_410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THA_411	COG0116	Belongs to the methyltransferase superfamily
THA_412	COG1993	acr, cog1993
THA_413	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
THA_415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
THA_416	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
THA_418	COG2264	protein methyltransferase activity
THA_419	COG0739	heme binding
THA_42	COG1355	regulation of microtubule-based process
THA_421	COG1607	acyl-coa hydrolase
THA_422	COG3246	L-lysine catabolic process to acetate
THA_423	COG0604	alcohol dehydrogenase
THA_424	COG1509	lysine 2,3-aminomutase activity
THA_425	COG2030	dehydratase
THA_428	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
THA_429	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THA_43	COG1450	Type ii and iii secretion system protein
THA_432	COG1136	(ABC) transporter
THA_438	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THA_440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
THA_441	COG0037	tRNA processing
THA_444	COG1968	undecaprenyl-diphosphatase activity
THA_445	COG1228	amidohydrolase
THA_448	COG0424	maF-like protein
THA_449	COG2003	Belongs to the UPF0758 family
THA_452	COG1215	transferase activity, transferring glycosyl groups
THA_453	COG1216	Glycosyl transferase, family 2
THA_458	COG0793	Belongs to the peptidase S41A family
THA_459	COG2226	methyltransferase
THA_462	COG1713	HD superfamily hydrolase involved in NAD metabolism
THA_464	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
THA_465	COG0009	L-threonylcarbamoyladenylate synthase
THA_467	COG0481	GTPase activity
THA_468	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
THA_469	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
THA_470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
THA_473	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
THA_475	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
THA_476	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
THA_477	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
THA_478	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
THA_479	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THA_480	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
THA_481	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
THA_484	COG1461	Dihydroxyacetone kinase
THA_486	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
THA_487	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
THA_488	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
THA_489	COG1785	Belongs to the alkaline phosphatase family
THA_491	COG0495	leucyl-tRNA aminoacylation
THA_497	COG0714	Associated with various cellular activities
THA_50	COG1122	ATPase activity
THA_501	COG0750	zinc metalloprotease
THA_502	COG3706	GGDEF domain
THA_502	COG0745	RESPONSE REGULATOR receiver
THA_504	COG3437	response regulator, receiver
THA_506	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
THA_508	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
THA_509	COG0543	2 iron, 2 sulfur cluster binding
THA_51	COG2813	Specifically methylates the guanine in position
THA_510	COG0167	dihydroorotate dehydrogenase activity
THA_511	COG0284	orotidine-5'-phosphate decarboxylase activity
THA_512	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
THA_514	COG2183	response to ionizing radiation
THA_515	COG0835	chemotaxis
THA_516	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
THA_518	COG1013	pyruvate-flavodoxin oxidoreductase activity
THA_519	COG0674	pyruvate-flavodoxin oxidoreductase activity
THA_520	COG1144	Oxidoreductase
THA_521	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THA_522	COG1543	Belongs to the glycosyl hydrolase 57 family
THA_524	COG1760	l-serine dehydratase
THA_53	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
THA_530	COG0784	Response regulator, receiver
THA_530	COG3437	response regulator, receiver
THA_534	COG4786	Flagellar basal body rod
THA_534	COG1256	bacterial-type flagellum assembly
THA_534	COG1256	bacterial-type flagellum assembly
THA_534	COG4786	Flagellar basal body rod
THA_537	COG0840	transmembrane signaling receptor activity
THA_538	COG0668	transmembrane transport
THA_539	COG0180	Tryptophanyl-tRNA synthetase
THA_540	COG1067	ATP-dependent peptidase activity
THA_541	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
THA_544	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
THA_546	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
THA_547	COG0537	adenosine 5'-monophosphoramidase activity
THA_549	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
THA_550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
THA_555	COG2759	Belongs to the formate--tetrahydrofolate ligase family
THA_556	COG5002	protein histidine kinase activity
THA_557	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
THA_559	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
THA_559	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
THA_56	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
THA_560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
THA_562	COG0006	proline dipeptidase activity
THA_566	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THA_567	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
THA_568	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THA_569	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
THA_571	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
THA_572	COG0355	proton-transporting ATP synthase activity, rotational mechanism
THA_573	COG1307	EDD domain protein, DegV family
THA_575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
THA_576	COG5002	protein histidine kinase activity
THA_577	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
THA_58	COG0681	Belongs to the peptidase S26 family
THA_580	COG0095	Lipoate-protein ligase
THA_581	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
THA_582	COG1278	Cold shock
THA_584	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THA_588	COG0196	riboflavin kinase activity
THA_589	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
THA_59	COG0335	large ribosomal subunit rRNA binding
THA_592	COG2252	PERMEase
THA_6	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
THA_60	COG4752	Belongs to the RNA methyltransferase TrmD family
THA_61	COG0336	Belongs to the RNA methyltransferase TrmD family
THA_610	COG1609	Transcriptional regulator
THA_611	COG1966	Carbon starvation protein
THA_612	COG3279	Response regulator of the LytR AlgR family
THA_613	COG3275	phosphorelay sensor kinase activity
THA_615	COG0395	ABC-type sugar transport system, permease component
THA_618	COG2373	Large extracellular alpha-helical protein
THA_62	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
THA_620	COG3234	Protein of unknown function (DUF1175)
THA_621	COG4946	Tricorn protease homolog
THA_621	COG1506	peptidase
THA_621	COG0823	Involved in the tonB-independent uptake of proteins
THA_622	COG0733	neurotransmitter:sodium symporter activity
THA_623	COG3706	GGDEF domain
THA_624	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
THA_626	COG5001	Diguanylate cyclase
THA_63	COG1837	Belongs to the UPF0109 family
THA_630	COG0081	regulation of translation
THA_631	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
THA_632	COG0250	Participates in transcription elongation, termination and antitermination
THA_633	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
THA_637	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
THA_638	COG0629	single-stranded DNA binding
THA_639	COG0360	Binds together with S18 to 16S ribosomal RNA
THA_64	COG0228	four-way junction DNA binding
THA_642	COG0772	Belongs to the SEDS family
THA_644	COG0752	glycyl-tRNA synthetase alpha subunit
THA_645	COG0751	glycine-tRNA ligase activity
THA_646	COG1592	Rubrerythrin
THA_647	COG0330	HflC and HflK could
THA_648	COG0330	HflC and HflK could
THA_649	COG0517	IMP dehydrogenase activity
THA_649	COG0516	GMP reductase activity
THA_65	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THA_650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
THA_651	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
THA_655	COG1122	ATPase activity
THA_658	COG2199	diguanylate cyclase activity
THA_663	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
THA_666	COG1525	nuclease
THA_669	COG1869	D-ribose catabolic process
THA_670	COG1129	ABC transporter
THA_671	COG1172	Belongs to the binding-protein-dependent transport system permease family
THA_672	COG1879	ABC-type sugar transport system periplasmic component
THA_674	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THA_676	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
THA_677	COG1328	CTP reductase activity
THA_68	COG1178	ABC-type Fe3 transport system permease component
THA_682	COG0719	Fe-S assembly protein
THA_685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
THA_688	COG1175	transmembrane transport
THA_689	COG3833	ABC-type maltose transport systems, permease component
THA_698	COG1805	sodium ion transport
THA_70	COG0058	SHG alpha-glucan phosphorylase activity
THA_701	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
THA_702	COG0463	Glycosyl transferase, family 2
THA_703	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THA_706	COG1233	COG1233 Phytoene dehydrogenase and related
THA_71	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THA_710	COG3706	GGDEF domain
THA_711	COG0542	response to heat
THA_712	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THA_715	COG1187	pseudouridine synthase activity
THA_717	COG1074	ATP-dependent DNA helicase activity
THA_722	COG0776	regulation of translation
THA_723	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
THA_724	COG0432	Pfam Uncharacterised protein family UPF0047
THA_726	COG0803	Belongs to the bacterial solute-binding protein 9 family
THA_727	COG1121	(ABC) transporter
THA_728	COG1108	ABC-type Mn2 Zn2 transport systems permease components
THA_73	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
THA_730	COG1960	acyl-CoA dehydrogenase activity
THA_731	COG2086	electron transfer activity
THA_736	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
THA_737	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
THA_738	COG0138	bifunctional purine biosynthesis protein purh
THA_739	COG0151	Belongs to the GarS family
THA_742	COG0438	transferase activity, transferring glycosyl groups
THA_742	COG0297	glycogen (starch) synthase activity
THA_746	COG0438	transferase activity, transferring glycosyl groups
THA_746	COG0297	glycogen (starch) synthase activity
THA_75	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
THA_75	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
THA_752	COG1131	(ABC) transporter
THA_757	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THA_758	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
THA_761	COG0436	Aminotransferase
THA_762	COG2045	Belongs to the ComB family
THA_765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
THA_77	COG0220	tRNA (guanine-N7-)-methyltransferase activity
THA_770	COG0601	transmembrane transport
THA_772	COG0444	Belongs to the ABC transporter superfamily
THA_773	COG4608	Belongs to the ABC transporter superfamily
THA_774	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
THA_775	COG2723	6-phospho-beta-galactosidase activity
THA_776	COG1609	Transcriptional regulator
THA_778	COG0105	UTP biosynthetic process
THA_78	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
THA_780	COG3864	Putative metallopeptidase domain
THA_782	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
THA_788	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
THA_790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
THA_792	COG1181	Belongs to the D-alanine--D-alanine ligase family
THA_793	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
THA_794	COG1406	Chemotaxis phosphatase CheX
THA_795	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
THA_796	COG0528	UMP kinase activity
THA_799	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
THA_800	COG2176	DNA-directed DNA polymerase activity
THA_801	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THA_802	COG1766	The M ring may be actively involved in energy transduction
THA_805	COG0333	Belongs to the bacterial ribosomal protein bL32 family
THA_806	COG0416	fatty acid biosynthetic process
THA_807	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
THA_808	COG0612	Peptidase, M16
THA_809	COG0612	Peptidase, M16
THA_811	COG4786	Flagellar basal body rod
THA_812	COG1077	Cell shape determining protein MreB Mrl
THA_822	COG1132	(ABC) transporter
THA_824	COG1151	hydroxylamine reductase activity
THA_825	COG1785	Belongs to the alkaline phosphatase family
THA_826	COG0305	Participates in initiation and elongation during chromosome replication
THA_827	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
THA_83	COG1363	Peptidase, m42
THA_830	COG0697	spore germination
THA_832	COG2211	Major facilitator Superfamily
THA_833	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
THA_834	COG0745	RESPONSE REGULATOR receiver
THA_835	COG1523	belongs to the glycosyl hydrolase 13 family
THA_843	COG0438	transferase activity, transferring glycosyl groups
THA_844	COG1653	transport
THA_847	COG0154	amidase activity
THA_856	COG1337	RAMP superfamily
THA_867	COG1088	dTDP-glucose 4,6-dehydratase activity
THA_870	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
THA_879	COG1215	transferase activity, transferring glycosyl groups
THA_881	COG0438	transferase activity, transferring glycosyl groups
THA_886	COG0438	transferase activity, transferring glycosyl groups
THA_889	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
THA_899	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
THA_90	COG2096	Adenosyltransferase
THA_901	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THA_902	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THA_908	COG1706	bacterial-type flagellum-dependent cell motility
THA_909	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
THA_91	COG2986	histidine ammonia-lyase
THA_911	COG0187	DNA topoisomerase II activity
THA_913	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
THA_914	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THA_915	COG0516	GMP reductase activity
THA_915	COG0517	IMP dehydrogenase activity
THA_916	COG1105	Belongs to the carbohydrate kinase PfkB family
THA_917	COG1131	(ABC) transporter
THA_92	COG0840	transmembrane signaling receptor activity
THA_926	COG1007	ATP synthesis coupled electron transport
THA_927	COG0205	6-phosphofructokinase activity
THA_928	COG1979	alcohol dehydrogenase
THA_93	COG0497	DNA recombination
THA_930	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
THA_931	COG0072	phenylalanine-tRNA ligase activity
THA_931	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THA_935	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THA_937	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
THA_94	COG2201	protein-glutamate methylesterase activity
THA_940	COG1175	transmembrane transport
THA_941	COG0395	ABC-type sugar transport system, permease component
THA_944	COG3706	GGDEF domain
THA_945	COG0445	tRNA wobble uridine modification
THA_946	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
THA_948	COG1392	Phosphate transport regulator
THA_949	COG0366	Alpha amylase catalytic
THA_950	COG0306	phosphate transporter
THA_951	COG0306	phosphate transporter
THA_955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THA_956	COG4869	propanediol catabolic process
THA_957	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
THA_958	COG0840	transmembrane signaling receptor activity
THA_959	COG1684	flagellar biosynthetic protein fliR
THA_960	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THA_962	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
THA_964	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
THA_965	COG2208	phosphoserine phosphatase activity
THA_965	COG2770	Histidine kinase
THA_966	COG0745	RESPONSE REGULATOR receiver
THA_969	COG1137	ATPase activity
THA_97	COG1013	pyruvate-flavodoxin oxidoreductase activity
THA_971	COG0513	Belongs to the DEAD box helicase family
THA_972	COG0242	peptide deformylase activity
THA_973	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
THA_975	COG0489	protein tyrosine kinase activity
THA_977	COG0488	(ABC) transporter
THA_978	COG0534	Mate efflux family protein
THA_98	COG2131	deaminase
THA_982	COG0446	pyridine nucleotide-disulphide oxidoreductase
THA_989	COG0840	transmembrane signaling receptor activity
THA_99	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
THA_991	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
THA_992	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
THA_993	COG0504	CTP synthase activity
THA_994	COG1546	Belongs to the CinA family
THA_994	COG1058	Belongs to the CinA family
THA_995	COG1609	Transcriptional regulator
THA_998	COG0210	DNA helicase