locus-tag	class	description
Tmel_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Tmel_0002	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
Tmel_0008	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Tmel_0014	ENOG4105C26	Dehydrogenase
Tmel_0016	ENOG4105DIH	basic membrane
Tmel_0017	ENOG4108JQ9	ABC transporter
Tmel_0018	ENOG4105UIB	(ABC) transporter
Tmel_0022	ENOG4105EPR	degv family
Tmel_0023	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Tmel_0024	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Tmel_0031	ENOG4105C3M	thioredoxin reductase
Tmel_0032	ENOG4108W2Y	isochorismatase
Tmel_0033	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Tmel_0036	ENOG4105FJ0	thiamine
Tmel_0037	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Tmel_0038	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Tmel_0039	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
Tmel_0041	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tmel_0042	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Tmel_0043	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Tmel_0044	ENOG4108R6K	riboflavin synthase, subunit alpha
Tmel_0045	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Tmel_0046	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Tmel_0047	ENOG4107YH3	SUF system FeS assembly protein, NifU family
Tmel_0048	ENOG4105C9B	Cysteine desulfurase
Tmel_0050	ENOG4105DIW	FeS assembly protein SUFB
Tmel_0052	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Tmel_0053	ENOG41083C3	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Tmel_0054	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Tmel_0056	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Tmel_0057	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Tmel_0058	ENOG4106M28	alanine racemase domain protein
Tmel_0060	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Tmel_0061	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Tmel_0063	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Tmel_0064	ENOG4105C8N	cysteinyl-tRNA synthetase
Tmel_0065	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Tmel_0066	ENOG4105C2W	permease
Tmel_0071	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Tmel_0072	ENOG4108JYZ	YitT family
Tmel_0073	ENOG4105GTG	Isochorismatase
Tmel_0074	ENOG4105PGM	cation diffusion facilitator family transporter
Tmel_0077	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Tmel_0079	ENOG4108JUB	Transcriptional regulator
Tmel_0080	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Tmel_0081	ENOG4105CPF	Cell wall formation (By similarity)
Tmel_0084	ENOG4105C5I	Dehydrogenase
Tmel_0085	ENOG4105D1Z	hydroxypyruvate reductase
Tmel_0086	ENOG4107S7H	nh(3)-dependent nad( ) synthetase
Tmel_0087	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Tmel_0088	ENOG41085Z1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Tmel_0090	ENOG41079KZ	Major Facilitator Superfamily
Tmel_0091	ENOG4108Z3G	3H domain protein
Tmel_0092	ENOG4108UT2	hemolysin iii
Tmel_0093	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Tmel_0095	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Tmel_0096	ENOG4105CN9	Peptidase m42 family protein
Tmel_0097	ENOG4105CN9	Peptidase m42 family protein
Tmel_0098	ENOG41065EC	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Tmel_0099	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Tmel_0100	ENOG4105KC4	UPF0296 protein
Tmel_0107	ENOG4105CKM	Branched-chain carboxylic acid kinase
Tmel_0108	ENOG4107RE7	phosphate butyryltransferase
Tmel_0109	ENOG4105CKM	Branched-chain carboxylic acid kinase
Tmel_0110	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Tmel_0111	ENOG4105C5R	Aminotransferase
Tmel_0112	ENOG4108JQ1	Dehydrogenase
Tmel_0113	ENOG4105D22	carbon starvation protein
Tmel_0114	ENOG4105DY9	regulatoR
Tmel_0115	ENOG4108HRK	Histidine kinase
Tmel_0117	ENOG4107S4Y	M20 DapE family protein YgeY
Tmel_0118	ENOG4105DBV	ornithine carbamoyltransferase
Tmel_0119	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
Tmel_0120	ENOG4107UUR	Chlorohydrolase aminohydrolase
Tmel_0121	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Tmel_0122	ENOG4105MCT	stage V sporulation protein S
Tmel_0123	ENOG4105CGH	5'-nucleotidase
Tmel_0124	ENOG4105BZ1	(ABC) transporter
Tmel_0130	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Tmel_0133	ENOG4105BZ1	(ABC) transporter
Tmel_0136	ENOG4107S85	alpha-2-macroglobulin domain protein
Tmel_0138	ENOG4108QJJ	Protein of unknown function (DUF1175)
Tmel_0141	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Tmel_0144	ENOG4105C8Q	Methyl-accepting chemotaxis
Tmel_0147	ENOG4105C3S	Mate efflux family protein
Tmel_0148	ENOG4105CPC	Aldo Keto reductase
Tmel_0151	ENOG4105CJ1	ABC, transporter
Tmel_0153	ENOG4105D1H	recombination factor protein RarA
Tmel_0154	ENOG4105D1H	recombination factor protein RarA
Tmel_0155	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Tmel_0157	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Tmel_0158	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Tmel_0160	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Tmel_0161	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Tmel_0162	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Tmel_0163	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Tmel_0167	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
Tmel_0168	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Tmel_0169	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Tmel_0174	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Tmel_0176	ENOG4105ZU5	s-layer protein
Tmel_0177	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Tmel_0179	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Tmel_0180	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Tmel_0181	ENOG4105KJJ	Uncharacterized ACR, COG1993
Tmel_0182	ENOG4105WMR	Protein CrcB homolog
Tmel_0184	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Tmel_0185	ENOG41082VF	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Tmel_0187	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Tmel_0188	ENOG4105DR5	peptidase
Tmel_0189	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
Tmel_0190	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
Tmel_0191	ENOG4105FRY	Dehydrogenase
Tmel_0192	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Tmel_0193	ENOG4108F01	MaoC domain protein
Tmel_0196	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
Tmel_0197	ENOG4107CHF	5,6-aminomutase beta subunit
Tmel_0200	ENOG410816Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Tmel_0206	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Tmel_0207	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Tmel_0208	ENOG4105CN9	Peptidase m42 family protein
Tmel_0210	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Tmel_0211	ENOG4105CI2	imidazolone-5-propionate hydrolase
Tmel_0214	ENOG4108Z03	MAF-like protein
Tmel_0215	ENOG4105W5Q	DNA repair protein (RadC
Tmel_0218	ENOG4105CND	Glycosyl transferase, family 2
Tmel_0224	ENOG4105CN1	protease
Tmel_0225	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Tmel_0228	ENOG4108WF2	Metal Dependent Phosphohydrolase
Tmel_0230	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Tmel_0231	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Tmel_0233	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Tmel_0234	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Tmel_0235	ENOG4108JIF	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Tmel_0236	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Tmel_0237	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Tmel_0239	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Tmel_0241	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Tmel_0242	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Tmel_0243	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Tmel_0244	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Tmel_0245	ENOG41084A9	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Tmel_0246	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
Tmel_0247	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
Tmel_0250	ENOG4105DP4	dak2 domain fusion protein ylov
Tmel_0252	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Tmel_0253	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Tmel_0254	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Tmel_0256	ENOG4105C8T	Leucyl-tRNA synthetase
Tmel_0260	ENOG4105DZP	Membrane-associated zinc metalloprotease
Tmel_0261	ENOG4105BZU	Histidine kinase
Tmel_0262	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_0263	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Tmel_0265	ENOG4107VJ5	dihydroorotase
Tmel_0266	ENOG4105I47	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Tmel_0267	ENOG4107W93	Dihydroorotate dehydrogenase
Tmel_0268	ENOG4107YPM	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Tmel_0269	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Tmel_0275	ENOG4108V3W	Chemotaxis protein, CheW
Tmel_0276	ENOG4105C25	Primosomal protein n'
Tmel_0278	ENOG4105VEQ	Cold shock protein
Tmel_0279	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Tmel_0280	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
Tmel_0284	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Tmel_0285	ENOG4105BZU	Histidine kinase
Tmel_0286	ENOG4105MS2	ribosomal subunit Interface protein
Tmel_0288	ENOG4105EPR	degv family
Tmel_0289	ENOG41082J0	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Tmel_0290	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Tmel_0291	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Tmel_0292	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Tmel_0293	ENOG41085KK	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Tmel_0294	ENOG4108BYY	F-type ATPase subunit b
Tmel_0295	ENOG410855G	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Tmel_0299	ENOG4105DC7	peptidase M24
Tmel_0300	ENOG41084RN	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Tmel_0301	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Tmel_0302	ENOG4107S82	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Tmel_0303	ENOG4105BZU	Histidine kinase
Tmel_0304	ENOG4105CKU	formyltetrahydrofolate synthetase
Tmel_0305	ENOG4105D82	Glutamate dehydrogenase
Tmel_0310	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Tmel_0312	ENOG4107YU2	histidine triad (hIT) protein
Tmel_0313	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Tmel_0315	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Tmel_0317	ENOG4105U6W	MutT NUDIX family protein
Tmel_0318	ENOG4107SJN	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Tmel_0319	ENOG4105DAN	ATP-dependent protease
Tmel_0320	ENOG4105C31	Tryptophanyl-tRNA synthetase
Tmel_0321	ENOG4105D64	Mechanosensitive ion channel
Tmel_0322	ENOG4105C8Q	Methyl-accepting chemotaxis
Tmel_0328	ENOG4105E1Q	flagellar hook-associated protein
Tmel_0328	ENOG4105E1Q	flagellar hook-associated protein
Tmel_0331	ENOG4105F8J	Adenylate Guanylate cyclase
Tmel_0335	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_0337	ENOG4105EJQ	L-serine dehydratase
Tmel_0339	ENOG4107RFW	hydrolase family 57
Tmel_0340	ENOG4105EJ5	oxidoreductase gamma subunit
Tmel_0341	ENOG4105WGB	oxidoreductase, delta subunit
Tmel_0342	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Tmel_0343	ENOG4105DDK	oxidoreductase, beta subunit
Tmel_0344	ENOG4105ESV	Glycosyl transferase, family 4
Tmel_0346	ENOG4105C8Q	Methyl-accepting chemotaxis
Tmel_0347	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Tmel_0348	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Tmel_0359	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
Tmel_0364	ENOG4105CG5	Glycosyl transferase (Group 1
Tmel_0366	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Tmel_0367	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Tmel_0372	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Tmel_0373	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Tmel_0376	ENOG4105CHM	Aminotransferase
Tmel_0377	ENOG4108N5B	2-phosphosulfolactate phosphatase
Tmel_0379	ENOG4105BZ4	penicillin-binding protein
Tmel_0381	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Tmel_0383	ENOG4105EZM	VWA-like domain (DUF2201)
Tmel_0386	ENOG4107QNG	Phosphoribosylglycinamide synthetase
Tmel_0387	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Tmel_0388	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Tmel_0394	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Tmel_0402	ENOG4105DZR	Type I site-specific deoxyribonuclease
Tmel_0406	ENOG4108IUW	ABC transporter
Tmel_0407	ENOG4107QWP	ABC-2 type transporter
Tmel_0408	ENOG4105CN1	protease
Tmel_0410	ENOG4107HP6	Transcriptional regulator
Tmel_0413	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Tmel_0414	ENOG4105VCQ	rubredoxin
Tmel_0419	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Tmel_0423	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
Tmel_0424	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
Tmel_0425	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Tmel_0429	ENOG4105K70	DNA-binding protein
Tmel_0430	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Tmel_0431	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Tmel_0433	ENOG4107XSR	periplasmic solute binding protein
Tmel_0434	ENOG4105FDK	ABC transporter
Tmel_0435	ENOG41080V6	ABC-3 protein
Tmel_0437	ENOG4105DTN	riboflavin biosynthesis protein ribF
Tmel_0438	ENOG4105CSM	endonuclease III
Tmel_0441	ENOG4105C7N	Xanthine uracil vitamin C permease
Tmel_0451	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Tmel_0454	ENOG4105CIG	ABC transporter
Tmel_0457	ENOG41062JF	Transcriptional regulator
Tmel_0458	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Tmel_0459	ENOG4108IUM	Glycogen debranching enzyme
Tmel_0460	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tmel_0461	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Tmel_0463	ENOG410631K	Membrane
Tmel_0464	ENOG4105DFF	Rod shape-determining protein mreb
Tmel_0465	ENOG4105CGA	flagellar basal-body rod protein FlgG
Tmel_0466	ENOG4105CGA	flagellar basal-body rod protein FlgG
Tmel_0469	ENOG4105E5Q	amino acid AbC transporter
Tmel_0470	ENOG4106TNF	Periplasmic binding protein
Tmel_0471	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Tmel_0472	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Tmel_0473	ENOG41085U1	50S ribosomal protein L32
Tmel_0476	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Tmel_0477	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Tmel_0479	ENOG4108IAB	Phoh family
Tmel_0482	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Tmel_0483	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
Tmel_0484	ENOG4108W5Z	CheC domain protein
Tmel_0485	ENOG41083B7	nucleosidase (EC 3.2.2.9)
Tmel_0486	ENOG4105CPF	Cell wall formation (By similarity)
Tmel_0487	ENOG4108MUZ	hydrolase
Tmel_0488	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Tmel_0491	ENOG4107QIZ	NADH dehydrogenase
Tmel_0495	ENOG4105Y5S	NADH ubiquinone oxidoreductase, 24 kD
Tmel_0497	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_0498	ENOG4105BZU	Histidine kinase
Tmel_0500	ENOG4105CD3	dihydroorotase
Tmel_0501	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tmel_0502	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tmel_0503	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Tmel_0504	ENOG41081WB	50s ribosomal protein L10
Tmel_0507	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Tmel_0508	ENOG4105CAQ	asparagine synthetase
Tmel_0509	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Tmel_0510	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Tmel_0511	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
Tmel_0515	ENOG4107TVC	Glycosyl transferase, family 2
Tmel_0516	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Tmel_0517	ENOG4105CDU	Replicative dna helicase
Tmel_0521	ENOG4105KME	endoribonuclease L-psp
Tmel_0524	ENOG4108Z5K	methylglyoxal synthase
Tmel_0527	ENOG4105C5S	asparaginyl-tRNA synthetase
Tmel_0528	ENOG4105CTD	carboxy-peptidase
Tmel_0531	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Tmel_0533	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
Tmel_0534	ENOG4107Y7Q	pfkb domain protein
Tmel_0535	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Tmel_0542	ENOG41085TI	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Tmel_0546	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
Tmel_0547	ENOG4108RU0	short-chain dehydrogenase reductase
Tmel_0550	ENOG4107QIV	Cytochrome c biogenesis protein
Tmel_0554	ENOG4108JU3	Alkyl hydroperoxide reductase
Tmel_0557	ENOG4105MQ3	flagellar protein FliS
Tmel_0560	ENOG4108JQ7	(ABC) transporter
Tmel_0563	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Tmel_0564	ENOG4108J59	Extracellular solute-binding protein, family 5
Tmel_0565	ENOG4106H78	methyltransferase
Tmel_0566	ENOG4105D38	putrescine abc transporter
Tmel_0567	ENOG4105F38	ABC transporter, permease
Tmel_0568	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Tmel_0569	ENOG4107RUE	extracellular solute-binding protein family 1
Tmel_0570	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Tmel_0571	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Tmel_0575	ENOG4108UQV	Membrane
Tmel_0577	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Tmel_0578	ENOG4105CTJ	Metal Dependent Phosphohydrolase
Tmel_0583	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
Tmel_0585	ENOG4107QX3	carboxylase
Tmel_0586	ENOG4108ZVT	methylmalonyl-coA epimerase
Tmel_0589	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Tmel_0594	ENOG4105EG2	ABC transporter, permease
Tmel_0595	ENOG4105D56	permease protein
Tmel_0596	ENOG4107FKK	extracellular solute-binding protein family 1
Tmel_0597	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Tmel_0598	ENOG4105DYB	Isoaspartyl dipeptidase
Tmel_0601	ENOG4105DIW	FeS assembly protein SUFB
Tmel_0604	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Tmel_0616	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
Tmel_0617	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Tmel_0620	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
Tmel_0621	ENOG4105BZU	Histidine kinase
Tmel_0622	ENOG4105I03	Flagellin
Tmel_0623	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Tmel_0626	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Tmel_0627	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Tmel_0628	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Tmel_0630	ENOG4107RIZ	hflk protein
Tmel_0631	ENOG4108RAC	Rubrerythrin
Tmel_0632	ENOG4107RFA	Glycyl-tRNA synthetase beta subunit
Tmel_0633	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
Tmel_0635	ENOG4105CNI	cell division protein FtsW
Tmel_0636	ENOG41083EQ	Binds together with S18 to 16S ribosomal RNA (By similarity)
Tmel_0637	ENOG4108UUM	single-stranded DNA-binding protein
Tmel_0638	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Tmel_0639	ENOG41086IP	50S ribosomal protein L33
Tmel_0640	ENOG410683Z	Preprotein translocase SecE subunit
Tmel_0641	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Tmel_0642	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Tmel_0643	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Tmel_0645	ENOG4105BZU	Histidine kinase
Tmel_0646	ENOG41084X0	Dihydrofolate reductase
Tmel_0649	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
Tmel_0651	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
Tmel_0653	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Tmel_0654	ENOG4105C10	Electron transfer flavoprotein
Tmel_0655	ENOG4105BZJ	Electron transfer flavoprotein
Tmel_0656	ENOG4105C1G	acyl-Coa dehydrogenase
Tmel_0663	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Tmel_0665	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Tmel_0666	ENOG4107UKG	Glycosyl transferase, family 4
Tmel_0668	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Tmel_0669	ENOG4105TZT	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Tmel_0671	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tmel_0673	ENOG4107Z5F	Aminotransferase class IV
Tmel_0674	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Tmel_0675	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Tmel_0677	ENOG4105BZ1	(ABC) transporter
Tmel_0686	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Tmel_0689	ENOG4105D17	glycoside hydrolase, family 3 domain protein
Tmel_0691	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Tmel_0692	ENOG4105DRS	transport system, permease
Tmel_0694	ENOG4105CE4	GlcNAc 6-P deacetylase
Tmel_0695	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Tmel_0697	ENOG41081F0	Precorrin-8x methylmutase
Tmel_0698	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Tmel_0699	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Tmel_0700	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Tmel_0702	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Tmel_0703	ENOG4108P62	biosynthesis protein (CbiG)
Tmel_0704	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Tmel_0705	ENOG4108JTQ	reductase
Tmel_0706	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Tmel_0707	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Tmel_0709	ENOG4105D52	delta-aminolevulinic acid dehydratase
Tmel_0710	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Tmel_0711	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Tmel_0712	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Tmel_0715	ENOG4108JJB	ABC transporter
Tmel_0718	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Tmel_0720	ENOG4108V0P	LemA family
Tmel_0723	ENOG410813F	Putative esterase
Tmel_0725	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Tmel_0726	ENOG4105CJ3	phosphate transporter
Tmel_0729	ENOG4105C3R	Methionine synthase
Tmel_0731	ENOG4105SYT	Methylenetetrahydrofolate reductase
Tmel_0734	ENOG4105CFH	Aspartokinase
Tmel_0736	ENOG4105CG3	alpha amylase, catalytic region
Tmel_0738	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Tmel_0740	ENOG4105CJ1	ABC, transporter
Tmel_0742	ENOG4108MRH	transcriptional regulatory protein
Tmel_0744	ENOG4105CUT	histidyl-tRNA synthetase
Tmel_0747	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
Tmel_0749	ENOG4105C8Q	Methyl-accepting chemotaxis
Tmel_0750	ENOG4105BZU	Histidine kinase
Tmel_0751	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
Tmel_0754	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Tmel_0760	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Tmel_0761	ENOG4105DTQ	mandelate racemase muconate lactonizing
Tmel_0762	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Tmel_0765	ENOG4107V4V	glycoside hydrolase family 4
Tmel_0769	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Tmel_0770	ENOG4105CG3	alpha amylase, catalytic region
Tmel_0772	ENOG4105CPI	Metal Dependent Phosphohydrolase
Tmel_0773	ENOG4105BZU	Histidine kinase
Tmel_0774	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Tmel_0777	ENOG4105EMN	RNA polymerase sigma factor
Tmel_0779	ENOG4105C4R	Atp-dependent dna helicase
Tmel_0782	ENOG4105ETE	Transcriptional regulator (LacI family
Tmel_0783	ENOG4105CEV	competence damage-inducible protein
Tmel_0784	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Tmel_0785	ENOG4107RU2	Histidinol phosphate phosphatase, HisJ family
Tmel_0786	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Tmel_0788	ENOG41080JC	Protein of unknown function DUF47
Tmel_0789	ENOG4105CJ3	phosphate transporter
Tmel_0790	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
Tmel_0797	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Tmel_0798	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
Tmel_0803	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Tmel_0804	ENOG4105MKQ	Monovalent cation H antiporter subunit C
Tmel_0805	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Tmel_0806	ENOG4105CTQ	phosphohexokinase
Tmel_0807	ENOG4107QW4	alcohol dehydrogenase
Tmel_0808	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Tmel_0809	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Tmel_0813	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Tmel_0815	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Tmel_0819	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Tmel_0820	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Tmel_0821	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Tmel_0822	ENOG4105BZU	Histidine kinase
Tmel_0823	ENOG4108UH6	UPF0754 membrane protein
Tmel_0824	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Tmel_0826	ENOG4107ZMQ	sugar fermentation stimulation protein
Tmel_0829	ENOG41080HT	Transcriptional regulator, arsr family
Tmel_0830	ENOG4105UQX	Mate efflux family protein
Tmel_0831	ENOG4105C5H	ABC transporter
Tmel_0834	ENOG4105D1F	ATP-binding protein
Tmel_0836	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Tmel_0837	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Tmel_0838	ENOG4105C1J	atp-dependent rna helicase
Tmel_0840	ENOG4108IUZ	ABC transporter
Tmel_0843	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Tmel_0845	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Tmel_0847	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Tmel_0849	ENOG4105D00	flagellar biosynthetic protein flhB
Tmel_0850	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Tmel_0851	ENOG4105C8Q	Methyl-accepting chemotaxis
Tmel_0852	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Tmel_0853	ENOG4105BZU	Histidine kinase
Tmel_0854	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Tmel_0855	ENOG4108YZT	Adenosylcobinamide kinase
Tmel_0857	ENOG4107Z5K	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Tmel_0858	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Tmel_0859	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Tmel_0860	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Tmel_0861	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Tmel_0867	ENOG4105I08	Pseudouridine synthase
Tmel_0868	ENOG4105EEI	dihydropteroate synthase
Tmel_0870	ENOG4105C5R	Aminotransferase
Tmel_0871	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Tmel_0876	ENOG4105E2Y	ABC, transporter
Tmel_0882	ENOG4107Z0G	Domain of unknown function DUF20
Tmel_0883	ENOG4105HDK	L-asparaginase
Tmel_0889	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Tmel_0890	ENOG4105DFU	Cell wall formation (By similarity)
Tmel_0891	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Tmel_0904	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Tmel_0906	ENOG4105Z5Q	
Tmel_0908	ENOG4105KIJ	D-ornithine aminomutase S component
Tmel_0909	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
Tmel_0910	ENOG4105F8V	Hydrolase, tatD family
Tmel_0911	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Tmel_0915	ENOG4105BZU	Histidine kinase
Tmel_0917	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Tmel_0919	ENOG4105EI2	Pseudouridine synthase
Tmel_0922	ENOG4105CA9	Pyruvate kinase
Tmel_0923	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Tmel_0924	ENOG4107N8V	50s ribosomal protein L35
Tmel_0925	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Tmel_0926	ENOG4105CE9	30S ribosomal protein S2
Tmel_0927	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Tmel_0928	ENOG4105VS8	Flagellar biosynthetic protein fliq
Tmel_0929	ENOG4105CN7	Flagellar biosynthetic protein FliP
Tmel_0931	ENOG4107YTP	response regulator receiver protein
Tmel_0932	ENOG4105YVF	chew protein
Tmel_0933	ENOG4105CBS	Chea signal transduction histidine kinase
Tmel_0935	ENOG4105DX0	Hemolysin A
Tmel_0937	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Tmel_0941	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Tmel_0943	ENOG4105CNI	cell division protein FtsW
Tmel_0944	ENOG4105CSA	Coproporphyrinogen iii oxidase
Tmel_0946	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Tmel_0947	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Tmel_0948	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Tmel_0949	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Tmel_0950	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Tmel_0951	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Tmel_0952	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Tmel_0953	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Tmel_0954	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Tmel_0955	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Tmel_0956	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Tmel_0957	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Tmel_0958	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Tmel_0959	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Tmel_0960	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Tmel_0961	ENOG41084ME	50s ribosomal protein l29
Tmel_0962	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Tmel_0963	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Tmel_0964	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Tmel_0965	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Tmel_0966	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Tmel_0967	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Tmel_0968	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Tmel_0969	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Tmel_0970	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Tmel_0971	ENOG4105VPB	50S ribosomal protein L30
Tmel_0972	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Tmel_0973	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Tmel_0974	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Tmel_0976	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Tmel_0977	ENOG41086MH	50S ribosomal protein L36
Tmel_0978	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Tmel_0979	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Tmel_0980	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Tmel_0981	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tmel_0982	ENOG4108ZT0	50S ribosomal protein l17
Tmel_0983	ENOG4107XYV	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
Tmel_0984	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Tmel_0985	ENOG4105CDY	transcriptional regulatory protein
Tmel_0987	ENOG4105BZU	Histidine kinase
Tmel_0988	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Tmel_0989	ENOG4105C34	Pseudouridine synthase
Tmel_0990	ENOG4105C5F	glutamine synthetase
Tmel_0991	ENOG4105GSQ	TM1410 hypothetical-related protein
Tmel_0998	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_1001	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Tmel_1002	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_1003	ENOG4105NBF	ammecr1 domain protein
Tmel_1006	ENOG4107R56	PP-loop domain protein
Tmel_1007	ENOG4105CEM	UPF0597 protein
Tmel_1009	ENOG4105CMG	Carbohydrate kinase
Tmel_1010	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Tmel_1012	ENOG4105CMD	Transcriptional regulator, GntR family
Tmel_1013	ENOG4105CKB	glycosidase
Tmel_1014	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
Tmel_1015	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Tmel_1017	ENOG4107T3P	ABC, transporter
Tmel_1021	ENOG4108NVM	synthesis repressor PhaR
Tmel_1025	ENOG4105EQI	Metal Dependent Phosphohydrolase
Tmel_1026	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Tmel_1027	ENOG4105VB9	50S ribosomal protein l28
Tmel_1029	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tmel_1030	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Tmel_1031	ENOG4108UJD	30S ribosomal protein S9
Tmel_1032	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Tmel_1033	ENOG41081BK	membrane protein-like protein
Tmel_1034	ENOG4105K46	50S ribosomal protein l27
Tmel_1036	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Tmel_1038	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Tmel_1039	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Tmel_1040	ENOG4105MCT	stage V sporulation protein S
Tmel_1042	ENOG4105CBJ	Metal-dependent enzyme
Tmel_1043	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Tmel_1044	ENOG4107R84	Peptidase dimerisation domain
Tmel_1045	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Tmel_1046	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Tmel_1047	ENOG4105C3G	gtp-binding protein
Tmel_1048	ENOG4105KC4	UPF0296 protein
Tmel_1049	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Tmel_1050	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
Tmel_1053	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Tmel_1055	ENOG4105EA8	2-Nitropropane dioxygenase
Tmel_1064	ENOG4108KMV	Glycosyl transferase (Group 1
Tmel_1070	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Tmel_1075	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
Tmel_1088	ENOG4105MUN	Divergent AAA domain
Tmel_1120	ENOG4105C8Q	Methyl-accepting chemotaxis
Tmel_1121	ENOG4107S1Q	Phosphatase
Tmel_1122	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Tmel_1124	ENOG41083MZ	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Tmel_1125	ENOG4108ZC9	flagellar basal-body rod protein flgc
Tmel_1126	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
Tmel_1128	ENOG4105CFG	Acts as a chaperone (By similarity)
Tmel_1129	ENOG4105K8R	UPF0145 protein
Tmel_1130	ENOG4105F6J	Alpha beta hydrolase fold
Tmel_1132	ENOG4105DA5	(ABC) transporter
Tmel_1133	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
Tmel_1134	ENOG4105CHU	acetyl-coa acetyltransferase
Tmel_1136	ENOG4107QP7	CoA-transferase subunit A
Tmel_1137	ENOG4105G6Z	alkaline phosphatase
Tmel_1138	ENOG4105BZ8	glutamate synthase
Tmel_1139	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Tmel_1140	ENOG4108RVA	ribokinase
Tmel_1141	ENOG4105DKQ	ROK family
Tmel_1145	ENOG4105M3Z	response regulator
Tmel_1146	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Tmel_1147	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Tmel_1148	ENOG4105CBS	Chea signal transduction histidine kinase
Tmel_1152	ENOG4105BZS	acriflavin resistance protein
Tmel_1155	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Tmel_1156	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Tmel_1157	ENOG41081HM	2'-5' rna ligase
Tmel_1158	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Tmel_1159	ENOG4108489	Modulates RecA activity (By similarity)
Tmel_1160	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Tmel_1164	ENOG4108R86	Transcriptional regulator
Tmel_1165	ENOG41084K4	Binds the 23S rRNA (By similarity)
Tmel_1166	ENOG41060GV	RNA binding s1 domain protein
Tmel_1168	ENOG4107QIZ	NADH dehydrogenase
Tmel_1170	ENOG4107QIZ	NADH dehydrogenase
Tmel_1172	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
Tmel_1173	ENOG4105CCS	Glutamate formiminotransferase
Tmel_1174	ENOG4105ECY	inositol monophosphatase
Tmel_1175	ENOG4105CJN	penicillin-binding protein
Tmel_1176	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Tmel_1178	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Tmel_1180	ENOG4105KTH	gatB Yqey
Tmel_1181	ENOG41067B5	Histone deacetylase superfamily protein
Tmel_1182	ENOG4108YZG	isomerase
Tmel_1183	ENOG41082AN	stage II sporulation protein
Tmel_1184	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Tmel_1186	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tmel_1187	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Tmel_1188	ENOG4105DEF	Extracellular solute-binding protein, family 5
Tmel_1189	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Tmel_1190	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Tmel_1192	ENOG4108JQ7	(ABC) transporter
Tmel_1193	ENOG4105CXT	aspartate transcarbamylase
Tmel_1194	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_1195	ENOG4105G5W	regulator Fur family
Tmel_1196	ENOG4105D3R	alkyl hydroperoxide reductase
Tmel_1197	ENOG4105VCQ	rubredoxin
Tmel_1198	ENOG4105CNW	domain protein
Tmel_1199	ENOG41090A1	ferritin
Tmel_1201	ENOG4105MAX	Superoxide reductase
Tmel_1204	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_1206	ENOG4107104	thymidine kinase
Tmel_1207	ENOG4105CGH	5'-nucleotidase
Tmel_1209	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
Tmel_1210	ENOG4105SC1	monovalent cation H antiporter subunit E
Tmel_1211	ENOG410684G	monovalent cation H antiporter subunit F
Tmel_1214	ENOG4105D65	subunit l
Tmel_1215	ENOG4105MKQ	Monovalent cation H antiporter subunit C
Tmel_1216	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Tmel_1217	ENOG4105D65	subunit l
Tmel_1219	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Tmel_1220	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Tmel_1221	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Tmel_1229	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Tmel_1230	ENOG4105D7W	serine acetyltransferase
Tmel_1231	ENOG4105C6T	cysteine synthase
Tmel_1232	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Tmel_1233	ENOG4105C8V	SAICAR synthetase
Tmel_1234	ENOG4108A1T	Phosphoribosylformylglycinamidine synthase, purS
Tmel_1235	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Tmel_1236	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Tmel_1239	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
Tmel_1240	ENOG4108RE9	Phosphodiesterase
Tmel_1241	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Tmel_1242	ENOG4105CHM	Aminotransferase
Tmel_1243	ENOG4105C83	adenylosuccinate lyase
Tmel_1244	ENOG4107YCR	Transcriptional regulator, ARSR family
Tmel_1245	ENOG4105PGM	cation diffusion facilitator family transporter
Tmel_1258	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Tmel_1259	ENOG4105C87	Aminotransferase class I and II
Tmel_1264	ENOG4105BZA	Phosphoglycerate kinase
Tmel_1265	ENOG4105BZA	Phosphoglycerate kinase
Tmel_1266	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Tmel_1271	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Tmel_1272	ENOG4105D2N	Aldolase
Tmel_1275	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Tmel_1276	ENOG4107QHF	type ii secretion system protein e
Tmel_1278	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Tmel_1279	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Tmel_1280	ENOG4105KNE	Phosphatidate cytidylyltransferase
Tmel_1281	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Tmel_1282	ENOG4105DFF	Rod shape-determining protein mreb
Tmel_1285	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Tmel_1289	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Tmel_1292	ENOG4105W00	Flagellar hook capping protein
Tmel_1293	ENOG4105BZE	flagellar hook protein, FlgE
Tmel_1294	ENOG41068WV	flagellar FlbD family protein
Tmel_1295	ENOG4105E14	MotA TolQ exbB proton channel
Tmel_1296	ENOG4107XSU	flagellar motor protein motb
Tmel_1298	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Tmel_1299	ENOG4105DD5	Flagellar motor switch protein
Tmel_1300	ENOG4105C8J	)-transporter
Tmel_1302	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Tmel_1303	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Tmel_1304	ENOG4105CJW	magnesium transporter
Tmel_1306	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Tmel_1307	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Tmel_1310	ENOG4105E0A	ABC, transporter
Tmel_1314	ENOG4105WPN	DNA integration recombination invertion protein
Tmel_1315	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Tmel_1316	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Tmel_1319	ENOG4105C7W	Xanthine dehydrogenase
Tmel_1324	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Tmel_1327	ENOG4105C22	threonyL-tRNA synthetase
Tmel_1328	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_1329	ENOG4105F7J	membrane-bound serine protease
Tmel_1333	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Tmel_1335	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Tmel_1336	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Tmel_1339	ENOG4107QQG	Dehydrogenase
Tmel_1344	ENOG4105BZU	Histidine kinase
Tmel_1345	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Tmel_1346	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Tmel_1347	ENOG4105CPQ	Dehydrogenase
Tmel_1353	ENOG4107QJQ	Mate efflux family protein
Tmel_1355	ENOG4105DA5	(ABC) transporter
Tmel_1360	ENOG4108IJ0	Aspartate ammonia-lyase
Tmel_1361	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Tmel_1363	ENOG4105EAH	synthase
Tmel_1365	ENOG4105DBI	uridine monophosphokinase
Tmel_1366	ENOG4105DCI	Phosphohydrolase
Tmel_1367	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Tmel_1372	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Tmel_1373	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Tmel_1374	ENOG4105CHW	UPF0052 protein
Tmel_1375	ENOG4105CIE	May be required for sporulation (By similarity)
Tmel_1376	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Tmel_1377	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Tmel_1378	ENOG4105CRK	lysyL-tRNA synthetase
Tmel_1380	ENOG41082I2	s4 domain protein
Tmel_1382	ENOG4105BZ1	(ABC) transporter
Tmel_1384	ENOG4105C3U	ABC transporter
Tmel_1385	ENOG4108JQ7	(ABC) transporter
Tmel_1388	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Tmel_1393	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Tmel_1394	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Tmel_1395	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Tmel_1396	ENOG4105CZX	twitching motility protein
Tmel_1397	ENOG4105C6E	dna polymerase iii
Tmel_1398	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Tmel_1401	ENOG4105D78	K07001 NTE family protein
Tmel_1402	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Tmel_1404	ENOG4105C4K	Nad synthetase
Tmel_1408	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Tmel_1409	ENOG4105E3H	phosphoglycerate mutase
Tmel_1411	ENOG4105I3K	Ferric uptake regulator, Fur family
Tmel_1412	ENOG4105CHV	Transcription elongation factor NusA
Tmel_1413	ENOG4108396	Required for maturation of 30S ribosomal subunits (By similarity)
Tmel_1416	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Tmel_1418	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Tmel_1419	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Tmel_1420	ENOG4105VG1	fes assembly suf system protein
Tmel_1421	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Tmel_1422	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Tmel_1423	ENOG4107YM4	Beta-lactamase domain-containing protein
Tmel_1425	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Tmel_1431	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tmel_1432	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Tmel_1433	ENOG4107PHP	CheC --inhibitor of MCP methylation
Tmel_1437	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Tmel_1438	ENOG4105D7B	Flagellar biosynthesis protein flha
Tmel_1472	ENOG4108PNI	recT protein
Tmel_1473	ENOG4108NF7	phage-type endonuclease
Tmel_1479	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Tmel_1481	ENOG4105UHH	
Tmel_1487	ENOG4105EJ9	Membrane
Tmel_1490	ENOG4105MA4	psp1 domain protein
Tmel_1491	ENOG41061AI	Protein of unknown function (DUF2905)
Tmel_1492	ENOG4105K8N	protein family UPF0079, ATPase
Tmel_1493	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Tmel_1494	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Tmel_1496	ENOG4105BZU	Histidine kinase
Tmel_1497	ENOG4108HU6	Metal dependent phosphohydrolase
Tmel_1498	ENOG41084NJ	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Tmel_1500	ENOG4107V1F	Flagellar hook-associated 2 domain-containing protein
Tmel_1503	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Tmel_1505	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Tmel_1506	ENOG4105CCT	upf0313 protein
Tmel_1507	ENOG4105C37	(CBS) domain
Tmel_1508	ENOG4105KG3	cytidine deaminase
Tmel_1511	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Tmel_1513	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Tmel_1514	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Tmel_1516	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tmel_1517	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Tmel_1518	ENOG4105DXN	mazG family
Tmel_1519	ENOG4107WSY	Domain of unknown function DUF20
Tmel_1524	ENOG4105C0B	DNA polymerase III (alpha subunit)
Tmel_1525	ENOG4105DJV	ribulose-phosphate 3-epimerase
Tmel_1526	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Tmel_1527	ENOG4107XI1	DHH family
Tmel_1528	ENOG4105BZU	Histidine kinase
Tmel_1529	ENOG4105D4A	Cell wall formation (By similarity)
Tmel_1530	ENOG4105DFM	M18 family aminopeptidase
Tmel_1535	ENOG4105DG6	mannose-6-phosphate isomerase
Tmel_1537	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Tmel_1538	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Tmel_1539	ENOG4105DFA	alanine racemase domain protein
Tmel_1541	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Tmel_1542	ENOG4105QGT	Phosphate uptake regulator
Tmel_1544	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Tmel_1545	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Tmel_1549	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Tmel_1550	ENOG4107U53	septum site-determining protein minD
Tmel_1555	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Tmel_1557	ENOG41069ER	domain protein
Tmel_1559	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Tmel_1560	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Tmel_1561	ENOG4108KGH	TRANSCRIPTIONal
Tmel_1562	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Tmel_1565	ENOG4105N5T	Radical SAM Protein
Tmel_1566	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Tmel_1567	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Tmel_1568	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Tmel_1569	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Tmel_1571	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
Tmel_1572	ENOG4105D6A	Electron transport complex
Tmel_1574	ENOG4105DZB	Electron transport complex
Tmel_1575	ENOG4105DGN	Electron transport complex
Tmel_1576	ENOG4108J9M	Transporter
Tmel_1578	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Tmel_1579	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
Tmel_1580	ENOG4108IUK	alpha amylase, catalytic
Tmel_1581	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Tmel_1582	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
Tmel_1583	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Tmel_1584	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Tmel_1585	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Tmel_1586	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Tmel_1588	ENOG4105VKD	bioY protein
Tmel_1589	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Tmel_1590	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
Tmel_1592	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Tmel_1594	ENOG4107ZCS	Phosphomethylpyrimidine kinase
Tmel_1595	ENOG4105CTQ	phosphohexokinase
Tmel_1597	ENOG4107QW8	radical SAM domain protein
Tmel_1601	ENOG4107QHI	-hydrogenase
Tmel_1604	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Tmel_1605	ENOG4105C4K	Nad synthetase
Tmel_1606	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Tmel_1607	ENOG4105CJR	Integral membrane protein (MviN
Tmel_1608	ENOG4108R3D	Electron transport complex
Tmel_1609	ENOG4105C79	DNA protecting protein DprA
Tmel_1610	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Tmel_1612	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Tmel_1613	ENOG4105C1V	Peptidase, M16
Tmel_1614	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_1615	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Tmel_1616	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Tmel_1618	ENOG4105DRS	transport system, permease
Tmel_1619	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Tmel_1620	ENOG4105C9M	aspartyl-trna synthetase
Tmel_1621	ENOG41084GC	stage II sporulation protein
Tmel_1622	ENOG4107RB4	Cytidine monophosphate kinase
Tmel_1623	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Tmel_1624	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Tmel_1625	ENOG4105DIH	basic membrane
Tmel_1627	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_1628	ENOG41085QA	50S ribosomal protein l34
Tmel_1629	ENOG41084AH	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Tmel_1630	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Tmel_1631	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Tmel_1634	ENOG4105D0C	transport protein
Tmel_1635	ENOG4105C5F	glutamine synthetase
Tmel_1636	ENOG4105BZU	Histidine kinase
Tmel_1638	ENOG4105CS2	ec 3.2.1.21
Tmel_1643	ENOG4107RSD	Multi-copper polyphenol oxidoreductase laccase
Tmel_1648	ENOG4105BZ1	(ABC) transporter
Tmel_1650	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Tmel_1651	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Tmel_1652	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Tmel_1670	ENOG410695F	Crispr-associated protein, Csm1 family
Tmel_1672	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
Tmel_1674	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
Tmel_1682	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Tmel_1686	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Tmel_1688	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Tmel_1691	ENOG4107QMH	DNA methylase
Tmel_1695	ENOG4105VXP	Protein of unknown function DUF86
Tmel_1699	ENOG4107R3E	Citrate transporter
Tmel_1701	ENOG4105IRK	Glycosyl transferase (Group 1
Tmel_1702	ENOG4108IJ9	(ABC) transporter
Tmel_1716	ENOG4108IJ9	(ABC) transporter
Tmel_1717	ENOG4105IRK	Glycosyl transferase (Group 1
Tmel_1722	ENOG4105EJ9	Membrane
Tmel_1723	ENOG4107QSE	Dipeptidase
Tmel_1726	ENOG4105CJN	penicillin-binding protein
Tmel_1727	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Tmel_1728	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Tmel_1729	ENOG4105C6T	cysteine synthase
Tmel_1731	ENOG4105CPN	adenine deaminase
Tmel_1732	ENOG4108JQ7	(ABC) transporter
Tmel_1734	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Tmel_1736	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Tmel_1738	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Tmel_1739	ENOG4105CE1	Ferrous iron transport protein b
Tmel_1741	ENOG4105KQC	Competence protein
Tmel_1743	ENOG4105E4G	Type IV pilus
Tmel_1750	ENOG4108JJB	ABC transporter
Tmel_1751	ENOG4107Y49	methyltransferase
Tmel_1753	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Tmel_1755	ENOG410857I	Binds directly to 16S ribosomal RNA (By similarity)
Tmel_1756	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Tmel_1759	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Tmel_1760	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Tmel_1763	ENOG4105DBI	uridine monophosphokinase
Tmel_1764	ENOG4107QQB	Ribonuclease E
Tmel_1765	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Tmel_1767	ENOG4105DQU	oxidoreductase, subunit beta
Tmel_1770	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Tmel_1771	ENOG4105ZU5	s-layer protein
Tmel_1776	ENOG4105C8Q	Methyl-accepting chemotaxis
Tmel_1777	ENOG4105C84	Histidine ammonia-lyase
Tmel_1785	ENOG4105DER	m42 family
Tmel_1790	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Tmel_1791	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Tmel_1793	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Tmel_1794	ENOG4107SC1	transglycosylase
Tmel_1795	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
Tmel_1797	ENOG4105C0H	protease
Tmel_1798	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
Tmel_1799	ENOG4105C3F	Signal peptidase i
Tmel_1800	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Tmel_1801	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
Tmel_1802	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Tmel_1803	ENOG410836E	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Tmel_1804	ENOG41084QK	UPF0109 protein
Tmel_1805	ENOG4105K5M	30s ribosomal protein S16
Tmel_1808	ENOG4105F38	ABC transporter, permease
Tmel_1811	ENOG4105GRF	N-glycosylase DNA lyase
Tmel_1814	ENOG4105DBV	ornithine carbamoyltransferase
Tmel_1816	ENOG4105C8Q	Methyl-accepting chemotaxis
Tmel_1817	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tmel_1820	ENOG4107T3P	ABC, transporter
Tmel_1821	ENOG41088YS	Glycosyl transferase (Group 1
Tmel_1823	ENOG4105BZU	Histidine kinase
Tmel_1824	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Tmel_1825	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Tmel_1826	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Tmel_1827	ENOG4105C8U	phosphate abc transporter
Tmel_1830	ENOG4105C26	Dehydrogenase
Tmel_1831	ENOG41068WN	
Tmel_1832	ENOG41067TZ	transcriptional regulator, MarR family
Tmel_1834	ENOG4106VEM	tagatose-6-phosphate kinase
Tmel_1835	ENOG4105CHR	reductase
Tmel_1836	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Tmel_1837	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Tmel_1838	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tmel_1842	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Tmel_1843	ENOG4105C89	phosphohexose isomerase
Tmel_1845	ENOG41083IT	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Tmel_1846	ENOG4108KHP	Diguanylate cyclase
Tmel_1847	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Tmel_1848	ENOG4105F23	Fibronectin-binding protein
Tmel_1854	ENOG4105CDE	UPF0348 protein
Tmel_1855	ENOG4108JA2	transcriptioN-repair coupling factor
Tmel_1857	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
Tmel_1858	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Tmel_1859	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Tmel_1861	ENOG4107W7X	Aldolase
Tmel_1863	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Tmel_1864	ENOG4107QSA	Oxaloacetate decarboxylase
Tmel_1865	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Tmel_1867	ENOG4105C8Q	Methyl-accepting chemotaxis
Tmel_1870	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Tmel_1871	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Tmel_1872	ENOG4105D0C	transport protein
Tmel_1873	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Tmel_1874	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Tmel_1875	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Tmel_1876	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Tmel_1877	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Tmel_1879	ENOG4105C8Y	Acetylornithine aminotransferase
Tmel_1881	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Tmel_1882	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Tmel_1885	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Tmel_1886	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tmel_1887	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tmel_1888	ENOG4105C0A	alcohol dehydrogenase
Tmel_1892	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Tmel_1893	ENOG4105CGP	Urocanate hydratase
Tmel_1896	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Tmel_1897	ENOG4105WGB	oxidoreductase, delta subunit
Tmel_1898	ENOG4105D9Q	decarboxylase (Beta subunit)
Tmel_1899	ENOG4107QRG	dna polymerase iii
Tmel_1900	ENOG4108JJB	ABC transporter
Tmel_1901	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
Tmel_1902	ENOG4105CTQ	phosphohexokinase
Tmel_1903	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Tmel_1904	ENOG4107VRQ	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Tmel_1905	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Tmel_1906	ENOG4107Z7W	Preprotein translocase YajC subunit
Tmel_1907	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Tmel_1909	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Tmel_1910	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Tmel_1913	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Tmel_1916	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Tmel_1917	ENOG4105C2M	dna polymerase I
Tmel_1919	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Tmel_1920	ENOG4105C98	muts2 protein
Tmel_1922	ENOG4107QXV	Phosphate transporter
Tmel_1925	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Tmel_1926	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tmel_1928	ENOG4107RE7	phosphate butyryltransferase