locus-tag	class	description
Y592_00020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Y592_00025	ENOG4105C79	DNA protecting protein DprA
Y592_00030	ENOG4105D78	K07001 NTE family protein
Y592_00060	ENOG4105CJN	penicillin-binding protein
Y592_00070	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Y592_00075	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Y592_00080	ENOG4105C6T	cysteine synthase
Y592_00090	ENOG4105CPN	adenine deaminase
Y592_00095	ENOG4108JQ7	(ABC) transporter
Y592_00105	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Y592_00115	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Y592_00125	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Y592_00130	ENOG4105CE1	Ferrous iron transport protein b
Y592_00135	ENOG4105XFK	Ferrous iron transport protein A
Y592_00150	ENOG4105KQC	Competence protein
Y592_00155	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
Y592_00160	ENOG4105E4G	Type IV pilus
Y592_00195	ENOG4108JJB	ABC transporter
Y592_00200	ENOG4107Y49	methyltransferase
Y592_00205	ENOG4105VCQ	rubredoxin
Y592_00210	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Y592_00220	ENOG410857I	Binds directly to 16S ribosomal RNA (By similarity)
Y592_00225	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Y592_00240	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Y592_00245	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Y592_00260	ENOG4105DBI	uridine monophosphokinase
Y592_00270	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Y592_00275	ENOG4108UK2	deaminase
Y592_00280	ENOG4105DQU	oxidoreductase, subunit beta
Y592_00295	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Y592_00300	ENOG4105ZU5	s-layer protein
Y592_00310	ENOG4105C8Q	Methyl-accepting chemotaxis
Y592_00315	ENOG4105C84	Histidine ammonia-lyase
Y592_00355	ENOG4105DER	m42 family
Y592_00380	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Y592_00385	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Y592_00395	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Y592_00400	ENOG4107SC1	transglycosylase
Y592_00420	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
Y592_00425	ENOG4105C3F	Signal peptidase i
Y592_00430	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Y592_00435	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
Y592_00440	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Y592_00445	ENOG410836E	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Y592_00450	ENOG41084QK	UPF0109 protein
Y592_00455	ENOG4105K5M	30s ribosomal protein S16
Y592_00485	ENOG4105GRF	N-glycosylase DNA lyase
Y592_00500	ENOG4105DBV	ornithine carbamoyltransferase
Y592_00510	ENOG4105C8Q	Methyl-accepting chemotaxis
Y592_00515	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Y592_00530	ENOG4105DY9	regulatoR
Y592_00535	ENOG4105D22	carbon starvation protein
Y592_00555	ENOG4105C7H	Helicase, RecD TraA family
Y592_00575	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
Y592_00585	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
Y592_00595	ENOG410695F	Crispr-associated protein, Csm1 family
Y592_00625	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Y592_00630	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Y592_00635	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Y592_00650	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Y592_00665	ENOG4107T3P	ABC, transporter
Y592_00670	ENOG41088YS	Glycosyl transferase (Group 1
Y592_00680	ENOG4105BZU	Histidine kinase
Y592_00685	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Y592_00690	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Y592_00695	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Y592_00715	ENOG41068WN	
Y592_00730	ENOG4105DE4	1-phosphofructokinase
Y592_00735	ENOG4105CHR	reductase
Y592_00740	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Y592_00745	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Y592_00750	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Y592_00755	ENOG4105BZU	Histidine kinase
Y592_00770	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Y592_00775	ENOG4105C89	phosphohexose isomerase
Y592_00785	ENOG41083IT	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Y592_00790	ENOG4105BZU	Histidine kinase
Y592_00795	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Y592_00800	ENOG4105F23	Fibronectin-binding protein
Y592_00825	ENOG4105CDE	UPF0348 protein
Y592_00830	ENOG4108JA2	transcriptioN-repair coupling factor
Y592_00835	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
Y592_00840	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Y592_00845	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Y592_00855	ENOG4107W7X	Aldolase
Y592_00865	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Y592_00870	ENOG4107QSA	Oxaloacetate decarboxylase
Y592_00875	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Y592_00885	ENOG4105C8Q	Methyl-accepting chemotaxis
Y592_00900	ENOG4105G6Z	alkaline phosphatase
Y592_00910	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Y592_00915	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Y592_00920	ENOG4105D0C	transport protein
Y592_00930	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Y592_00940	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Y592_00945	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Y592_00950	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Y592_00955	ENOG4105CFH	Aspartokinase
Y592_00960	ENOG4105C8Y	Acetylornithine aminotransferase
Y592_00965	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Y592_00970	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Y592_00980	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Y592_00985	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Y592_00990	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Y592_00995	ENOG4105C0A	alcohol dehydrogenase
Y592_01000	ENOG4105DR4	Methyltransferase
Y592_01015	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Y592_01020	ENOG4105CGP	Urocanate hydratase
Y592_01025	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Y592_01035	ENOG4105D9Q	decarboxylase (Beta subunit)
Y592_01045	ENOG4108JJB	ABC transporter
Y592_01050	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
Y592_01055	ENOG4105CTQ	phosphohexokinase
Y592_01060	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Y592_01065	ENOG4107VRQ	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Y592_01070	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Y592_01075	ENOG4107Z7W	Preprotein translocase YajC subunit
Y592_01080	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Y592_01090	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Y592_01095	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Y592_01110	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Y592_01125	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Y592_01130	ENOG4105C2M	dna polymerase I
Y592_01140	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Y592_01145	ENOG4105C98	muts2 protein
Y592_01170	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Y592_01180	ENOG4105C5B	carbamate kinase
Y592_01185	ENOG4107RE7	phosphate butyryltransferase
Y592_01195	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Y592_01200	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
Y592_01210	ENOG4105DIH	basic membrane
Y592_01215	ENOG4108JQ9	ABC transporter
Y592_01220	ENOG4105UIB	(ABC) transporter
Y592_01245	ENOG4105EPR	degv family
Y592_01250	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Y592_01285	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Y592_01290	ENOG4105CAY	ferredoxin--nadp reductase
Y592_01295	ENOG4108W2Y	isochorismatase
Y592_01300	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Y592_01310	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Y592_01320	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Y592_01325	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Y592_01330	ENOG4105EHG	Permease protein
Y592_01340	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Y592_01355	ENOG4105F4P	)-transporter
Y592_01360	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Y592_01365	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Y592_01370	ENOG4108R6K	riboflavin synthase, subunit alpha
Y592_01375	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Y592_01380	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Y592_01385	ENOG4107YH3	SUF system FeS assembly protein, NifU family
Y592_01390	ENOG4105C9B	Cysteine desulfurase
Y592_01395	ENOG4105JRK	feS assembly protein SufD
Y592_01400	ENOG4105DIW	FeS assembly protein SUFB
Y592_01420	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Y592_01425	ENOG41083C3	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Y592_01450	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Y592_01455	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Y592_01460	ENOG4106M28	alanine racemase domain protein
Y592_01470	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Y592_01475	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Y592_01485	ENOG4105D29	Helix-turn-helix type 11 domain protein
Y592_01510	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Y592_01520	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Y592_01525	ENOG4105C8N	cysteinyl-tRNA synthetase
Y592_01530	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Y592_01535	ENOG4105C2W	permease
Y592_01545	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Y592_01550	ENOG4108JYZ	YitT family
Y592_01555	ENOG4105GTG	Isochorismatase
Y592_01575	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Y592_01585	ENOG4108JUB	Transcriptional regulator
Y592_01595	ENOG4105C5I	Dehydrogenase
Y592_01600	ENOG4105D1Z	hydroxypyruvate reductase
Y592_01605	ENOG4107S7H	nh(3)-dependent nad( ) synthetase
Y592_01610	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Y592_01615	ENOG41085Z1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Y592_01620	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Y592_01625	ENOG41079KZ	Major Facilitator Superfamily
Y592_01630	ENOG4108Z3G	3H domain protein
Y592_01635	ENOG4108UT2	hemolysin iii
Y592_01640	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Y592_01655	ENOG4105CN9	Peptidase m42 family protein
Y592_01660	ENOG4105CN9	Peptidase m42 family protein
Y592_01665	ENOG41065EC	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Y592_01670	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Y592_01675	ENOG4105KC4	UPF0296 protein
Y592_01710	ENOG4105CKM	Branched-chain carboxylic acid kinase
Y592_01715	ENOG4107RE7	phosphate butyryltransferase
Y592_01720	ENOG4105CKM	Branched-chain carboxylic acid kinase
Y592_01725	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Y592_01730	ENOG4105C5R	Aminotransferase
Y592_01735	ENOG4108JQ1	Dehydrogenase
Y592_01755	ENOG4107S4Y	M20 DapE family protein YgeY
Y592_01760	ENOG4105DBV	ornithine carbamoyltransferase
Y592_01805	ENOG4105MCT	stage V sporulation protein S
Y592_01815	ENOG4105CGH	5'-nucleotidase
Y592_01820	ENOG4105BZ1	(ABC) transporter
Y592_01850	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Y592_01855	ENOG4105VPX	protein, conserved in bacteria
Y592_01860	ENOG4105BZ1	(ABC) transporter
Y592_01880	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Y592_01895	ENOG4105UQX	Mate efflux family protein
Y592_01900	ENOG4105CPC	Aldo Keto reductase
Y592_01915	ENOG4105CJ1	ABC, transporter
Y592_01925	ENOG4105D1H	recombination factor protein RarA
Y592_01930	ENOG4105D1H	recombination factor protein RarA
Y592_01945	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Y592_01950	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Y592_01960	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Y592_01965	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Y592_01970	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Y592_01975	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Y592_01995	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
Y592_02000	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Y592_02005	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Y592_02010	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Y592_02025	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Y592_02040	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Y592_02045	ENOG4105KJJ	Uncharacterized ACR, COG1993
Y592_02050	ENOG4105WMR	Protein CrcB homolog
Y592_02060	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Y592_02065	ENOG41082VF	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Y592_02075	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Y592_02080	ENOG4105DR5	peptidase
Y592_02085	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
Y592_02090	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
Y592_02095	ENOG4105FRY	Dehydrogenase
Y592_02100	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Y592_02105	ENOG4108F01	MaoC domain protein
Y592_02115	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Y592_02120	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
Y592_02125	ENOG4107CHF	5,6-aminomutase beta subunit
Y592_02160	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Y592_02165	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Y592_02170	ENOG4105CN9	Peptidase m42 family protein
Y592_02180	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Y592_02185	ENOG4105CI2	imidazolone-5-propionate hydrolase
Y592_02200	ENOG4108Z03	MAF-like protein
Y592_02205	ENOG4105W5Q	DNA repair protein (RadC
Y592_02220	ENOG4105CND	Glycosyl transferase, family 2
Y592_02225	ENOG4105CKK	Glycosyl transferase, family 2
Y592_02250	ENOG4105CN1	protease
Y592_02270	ENOG4108WF2	Metal Dependent Phosphohydrolase
Y592_02275	ENOG4105W7A	Protein of unknown function (DUF503)
Y592_02280	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Y592_02285	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Y592_02295	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Y592_02300	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Y592_02305	ENOG4108JIF	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Y592_02310	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Y592_02315	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Y592_02325	ENOG41082Q0	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Y592_02335	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Y592_02340	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Y592_02345	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Y592_02350	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Y592_02355	ENOG41084A9	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Y592_02360	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
Y592_02365	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
Y592_02380	ENOG4105DP4	dak2 domain fusion protein ylov
Y592_02390	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Y592_02395	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Y592_02400	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Y592_02410	ENOG4105C8T	Leucyl-tRNA synthetase
Y592_02425	ENOG4105UA4	acetyltransferase
Y592_02430	ENOG4105DZP	Membrane-associated zinc metalloprotease
Y592_02435	ENOG4105BZU	Histidine kinase
Y592_02440	ENOG4108ESY	Metal dependent phosphohydrolase
Y592_02445	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Y592_02455	ENOG4107VJ5	dihydroorotase
Y592_02460	ENOG4105I47	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Y592_02465	ENOG4107W93	Dihydroorotate dehydrogenase
Y592_02470	ENOG4107YPM	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Y592_02475	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Y592_02505	ENOG4108V3W	Chemotaxis protein, CheW
Y592_02510	ENOG4105C25	Primosomal protein n'
Y592_02520	ENOG4105VEQ	Cold shock protein
Y592_02525	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Y592_02530	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
Y592_02550	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Y592_02555	ENOG4105BZU	Histidine kinase
Y592_02560	ENOG4105MS2	ribosomal subunit Interface protein
Y592_02570	ENOG4105EPR	degv family
Y592_02575	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Y592_02580	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Y592_02585	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Y592_02590	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Y592_02595	ENOG41085KK	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Y592_02600	ENOG4108BYY	F-type ATPase subunit b
Y592_02605	ENOG410855G	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Y592_02625	ENOG4105DC7	peptidase M24
Y592_02635	ENOG41084RN	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Y592_02640	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Y592_02650	ENOG4107S82	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Y592_02655	ENOG4105BZU	Histidine kinase
Y592_02660	ENOG4105CKU	formyltetrahydrofolate synthetase
Y592_02665	ENOG4105D82	Glutamate dehydrogenase
Y592_02670	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Y592_02680	ENOG4107YU2	histidine triad (hIT) protein
Y592_02685	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Y592_02695	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Y592_02705	ENOG4105U6W	MutT NUDIX family protein
Y592_02710	ENOG4107SJN	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Y592_02715	ENOG4105DAN	ATP-dependent protease
Y592_02720	ENOG4105C31	Tryptophanyl-tRNA synthetase
Y592_02725	ENOG4105D64	Mechanosensitive ion channel
Y592_02730	ENOG4105C8Q	Methyl-accepting chemotaxis
Y592_02745	ENOG4105E1Q	flagellar hook-associated protein
Y592_02745	ENOG4105E1Q	flagellar hook-associated protein
Y592_02750	ENOG4105DTJ	flagellar hook-associated protein
Y592_02760	ENOG4105F8J	Adenylate Guanylate cyclase
Y592_02780	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Y592_02795	ENOG4105EJQ	L-serine dehydratase
Y592_02805	ENOG4107RFW	hydrolase family 57
Y592_02810	ENOG4105EJ5	oxidoreductase gamma subunit
Y592_02815	ENOG4105WGB	oxidoreductase, delta subunit
Y592_02820	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Y592_02825	ENOG4105DDK	oxidoreductase, beta subunit
Y592_02835	ENOG4105ESV	Glycosyl transferase, family 4
Y592_02870	ENOG4105BZU	Histidine kinase
Y592_02880	ENOG4105VCQ	rubredoxin
Y592_02900	ENOG4108UH6	UPF0754 membrane protein
Y592_02905	ENOG4105FE9	pseudouridine synthase
Y592_02910	ENOG4105CMR	udp-glucose 4-epimerase
Y592_02915	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Y592_02930	ENOG4105K70	DNA-binding protein
Y592_02935	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Y592_02940	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Y592_02950	ENOG4107XSR	periplasmic solute binding protein
Y592_02955	ENOG4105FDK	ABC transporter
Y592_02960	ENOG41080V6	ABC-3 protein
Y592_02970	ENOG4105DTN	riboflavin biosynthesis protein ribF
Y592_02975	ENOG4105CSM	endonuclease III
Y592_02990	ENOG4105C7N	Xanthine uracil vitamin C permease
Y592_03045	ENOG4105CIG	ABC transporter
Y592_03060	ENOG41062JF	Transcriptional regulator
Y592_03065	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Y592_03070	ENOG4108IUM	Glycogen debranching enzyme
Y592_03075	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Y592_03080	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Y592_03090	ENOG410631K	Membrane
Y592_03095	ENOG4105DFF	Rod shape-determining protein mreb
Y592_03100	ENOG4105CGA	flagellar basal-body rod protein FlgG
Y592_03105	ENOG4105CGA	flagellar basal-body rod protein FlgG
Y592_03115	ENOG4105E5Q	amino acid AbC transporter
Y592_03120	ENOG4105EAB	amino acid AbC transporter
Y592_03125	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Y592_03130	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Y592_03135	ENOG41085U1	50S ribosomal protein L32
Y592_03155	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Y592_03160	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Y592_03165	ENOG4108IAB	Phoh family
Y592_03175	ENOG4106D4I	domain protein
Y592_03180	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Y592_03185	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
Y592_03190	ENOG4108W5Z	CheC domain protein
Y592_03195	ENOG41083B7	nucleosidase (EC 3.2.2.9)
Y592_03200	ENOG4105CPF	Cell wall formation (By similarity)
Y592_03220	ENOG4107QHI	-hydrogenase
Y592_03225	ENOG4107QIZ	NADH dehydrogenase
Y592_03230	ENOG4105GKE	subunit e
Y592_03245	ENOG4105Y5S	NADH ubiquinone oxidoreductase, 24 kD
Y592_03270	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Y592_03275	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Y592_03290	ENOG4105CHM	Aminotransferase
Y592_03295	ENOG4108N5B	2-phosphosulfolactate phosphatase
Y592_03305	ENOG4105BZ4	penicillin-binding protein
Y592_03315	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Y592_03325	ENOG4105EZM	VWA-like domain (DUF2201)
Y592_03335	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Y592_03340	ENOG4107QNG	Phosphoribosylglycinamide synthetase
Y592_03345	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Y592_03350	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Y592_03370	ENOG4105BZ1	(ABC) transporter
Y592_03380	ENOG4105CJA	serine threonine protein kinase
Y592_03415	ENOG4105BZ1	(ABC) transporter
Y592_03445	ENOG4105C8Q	Methyl-accepting chemotaxis
Y592_03460	ENOG4105EG2	ABC transporter, permease
Y592_03465	ENOG4105D56	permease protein
Y592_03470	ENOG4107FKK	extracellular solute-binding protein family 1
Y592_03475	ENOG4105DYB	Isoaspartyl dipeptidase
Y592_03485	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Y592_03490	ENOG4105DIW	FeS assembly protein SUFB
Y592_03495	ENOG4108IUZ	ABC transporter
Y592_03530	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
Y592_03540	ENOG4108RVA	ribokinase
Y592_03550	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Y592_03555	ENOG4105CNN	ABC, transporter
Y592_03560	ENOG4105C2J	ABC transporter
Y592_03565	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
Y592_03590	ENOG4105DTQ	mandelate racemase muconate lactonizing
Y592_03620	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Y592_03690	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Y592_03700	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
Y592_03710	ENOG4105BZU	Histidine kinase
Y592_03715	ENOG4105I03	Flagellin
Y592_03740	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Y592_03745	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Y592_03750	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Y592_03755	ENOG4105EPW	hflc protein
Y592_03760	ENOG4107RIZ	hflk protein
Y592_03765	ENOG4108RAC	Rubrerythrin
Y592_03770	ENOG4107RFA	Glycyl-tRNA synthetase beta subunit
Y592_03775	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
Y592_03785	ENOG4105CNI	cell division protein FtsW
Y592_03800	ENOG41083EQ	Binds together with S18 to 16S ribosomal RNA (By similarity)
Y592_03805	ENOG4108UUM	single-stranded DNA-binding protein
Y592_03810	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Y592_03825	ENOG41086IP	50S ribosomal protein L33
Y592_03835	ENOG410683Z	Preprotein translocase SecE subunit
Y592_03840	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Y592_03845	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Y592_03850	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Y592_03875	ENOG4105BZU	Histidine kinase
Y592_03885	ENOG41084X0	Dihydrofolate reductase
Y592_03905	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
Y592_03910	ENOG4108UQQ	Electron transport complex
Y592_03930	ENOG4105DAY	polysaccharide export protein
Y592_03940	ENOG4105DB7	PHP domain protein
Y592_03945	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Y592_03955	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Y592_03960	ENOG4107UKG	Glycosyl transferase, family 4
Y592_03975	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Y592_03980	ENOG4105TZT	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Y592_03985	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
Y592_03990	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Y592_04000	ENOG4107Z5F	Aminotransferase class IV
Y592_04005	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Y592_04010	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Y592_04060	ENOG4105J5G	Transferase hexapeptide repeat containing protein
Y592_04205	ENOG4105C30	Nad-dependent epimerase dehydratase
Y592_04210	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Y592_04220	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Y592_04235	ENOG4107T8Q	Glycosyl transferase (Group 1
Y592_04245	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Y592_04255	ENOG4105C5E	polysaccharide biosynthesis protein
Y592_04345	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
Y592_04375	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Y592_04385	ENOG4107ZMQ	sugar fermentation stimulation protein
Y592_04400	ENOG41080HT	Transcriptional regulator, arsr family
Y592_04405	ENOG4105UQX	Mate efflux family protein
Y592_04410	ENOG4105C5H	ABC transporter
Y592_04420	ENOG4105D1F	ATP-binding protein
Y592_04430	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Y592_04435	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Y592_04440	ENOG4105C1J	atp-dependent rna helicase
Y592_04450	ENOG4108IUZ	ABC transporter
Y592_04465	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Y592_04475	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Y592_04485	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Y592_04495	ENOG4105D00	flagellar biosynthetic protein flhB
Y592_04500	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Y592_04505	ENOG4106YBV	Methyl-accepting chemotaxis
Y592_04510	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Y592_04515	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
Y592_04520	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Y592_04545	ENOG4105CJ3	phosphate transporter
Y592_04550	ENOG41080JC	Protein of unknown function DUF47
Y592_04570	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Y592_04575	ENOG4107RU2	Histidinol phosphate phosphatase, HisJ family
Y592_04580	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Y592_04585	ENOG4105CEV	competence damage-inducible protein
Y592_04590	ENOG4105ETE	Transcriptional regulator (LacI family
Y592_04605	ENOG4105C4R	Atp-dependent dna helicase
Y592_04615	ENOG4105EMN	RNA polymerase sigma factor
Y592_04630	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Y592_04635	ENOG4105BZU	Histidine kinase
Y592_04650	ENOG4105CG3	alpha amylase, catalytic region
Y592_04655	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Y592_04670	ENOG4105ETE	Transcriptional regulator (LacI family
Y592_04675	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Y592_04690	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Y592_04695	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
Y592_04700	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Y592_04725	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Y592_04735	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Y592_04740	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
Y592_04745	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
Y592_04750	ENOG4105BZU	Histidine kinase
Y592_04755	ENOG4105C8Q	Methyl-accepting chemotaxis
Y592_04765	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
Y592_04780	ENOG4105CUT	histidyl-tRNA synthetase
Y592_04790	ENOG4108MRH	transcriptional regulatory protein
Y592_04800	ENOG4105CJ1	ABC, transporter
Y592_04810	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Y592_04815	ENOG4105CG3	alpha amylase, catalytic region
Y592_04825	ENOG4105C8Q	Methyl-accepting chemotaxis
Y592_04835	ENOG4105VZ8	Transcriptional regulator
Y592_04850	ENOG4105C8Q	Methyl-accepting chemotaxis
Y592_04855	ENOG4105ZXU	NLP P60 protein
Y592_04865	ENOG4108ESY	Metal dependent phosphohydrolase
Y592_04875	ENOG4108V0P	LemA family
Y592_04880	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Y592_04890	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Y592_04895	ENOG4105CE4	GlcNAc 6-P deacetylase
Y592_04905	ENOG4105DRS	transport system, permease
Y592_04910	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Y592_04920	ENOG4105D17	glycoside hydrolase, family 3 domain protein
Y592_04935	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Y592_04990	ENOG4107RA4	Glycosyl transferase (Group 1
Y592_05005	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Y592_05015	ENOG4105BZU	Histidine kinase
Y592_05020	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Y592_05025	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Y592_05040	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Y592_05060	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Y592_05080	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Y592_05085	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Y592_05090	ENOG4107QW4	alcohol dehydrogenase
Y592_05095	ENOG4105CTQ	phosphohexokinase
Y592_05100	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Y592_05105	ENOG4108ZE9	Monovalent cation H antiporter subunit C
Y592_05110	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Y592_05115	ENOG4105BZU	Histidine kinase
Y592_05140	ENOG4107Z5K	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Y592_05145	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Y592_05150	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Y592_05155	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Y592_05175	ENOG4105I08	Pseudouridine synthase
Y592_05180	ENOG4105EEI	dihydropteroate synthase
Y592_05200	ENOG4108SNK	aliphatic sulfonates import ATP-binding protein SsuB
Y592_05240	ENOG4107Z0G	Domain of unknown function DUF20
Y592_05245	ENOG4105HDK	L-asparaginase
Y592_05275	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Y592_05285	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Y592_05360	ENOG4105KIJ	D-ornithine aminomutase S component
Y592_05365	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
Y592_05370	ENOG4105F8V	Hydrolase, tatD family
Y592_05375	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Y592_05405	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Y592_05415	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Y592_05420	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Y592_05430	ENOG4105CSA	Coproporphyrinogen iii oxidase
Y592_05435	ENOG4105CNI	cell division protein FtsW
Y592_05445	ENOG4105BZU	Histidine kinase
Y592_05450	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Y592_05460	ENOG4105DX0	Hemolysin A
Y592_05470	ENOG4105CBS	Chea signal transduction histidine kinase
Y592_05475	ENOG4105YVF	chew protein
Y592_05480	ENOG4107YTP	response regulator receiver protein
Y592_05490	ENOG4105CN7	Flagellar biosynthetic protein FliP
Y592_05495	ENOG4105VS8	Flagellar biosynthetic protein fliq
Y592_05500	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Y592_05505	ENOG4105CE9	30S ribosomal protein S2
Y592_05510	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Y592_05515	ENOG4107N8V	50s ribosomal protein L35
Y592_05520	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Y592_05540	ENOG4105CA9	Pyruvate kinase
Y592_05555	ENOG4105EI2	Pseudouridine synthase
Y592_05570	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Y592_05575	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Y592_05580	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Y592_05585	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Y592_05590	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Y592_05595	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Y592_05600	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Y592_05605	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Y592_05610	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Y592_05615	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Y592_05620	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Y592_05625	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Y592_05630	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Y592_05635	ENOG41084ME	50s ribosomal protein l29
Y592_05640	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Y592_05645	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Y592_05650	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Y592_05655	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Y592_05660	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Y592_05665	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Y592_05670	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Y592_05675	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Y592_05680	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Y592_05685	ENOG4105VPB	50S ribosomal protein L30
Y592_05690	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Y592_05695	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Y592_05700	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Y592_05710	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Y592_05715	ENOG41086MH	50S ribosomal protein L36
Y592_05720	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Y592_05725	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Y592_05730	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Y592_05735	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Y592_05740	ENOG4108ZT0	50S ribosomal protein l17
Y592_05745	ENOG4107XYV	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
Y592_05750	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Y592_05755	ENOG4105CDY	transcriptional regulatory protein
Y592_05765	ENOG4105BZU	Histidine kinase
Y592_05775	ENOG4105C34	Pseudouridine synthase
Y592_05780	ENOG4105C5F	glutamine synthetase
Y592_05785	ENOG4105GSQ	TM1410 hypothetical-related protein
Y592_05825	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Y592_05840	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Y592_05845	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Y592_05850	ENOG4105NBF	ammecr1 domain protein
Y592_05865	ENOG4107R56	PP-loop domain protein
Y592_05870	ENOG4105CEM	UPF0597 protein
Y592_05880	ENOG4105CMG	Carbohydrate kinase
Y592_05885	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Y592_05905	ENOG4108NVM	synthesis repressor PhaR
Y592_05925	ENOG4105EQI	Metal Dependent Phosphohydrolase
Y592_05930	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Y592_05940	ENOG4105VB9	50S ribosomal protein l28
Y592_05950	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Y592_05955	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Y592_05960	ENOG4108UJD	30S ribosomal protein S9
Y592_05965	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Y592_05970	ENOG41081BK	membrane protein-like protein
Y592_05975	ENOG4105K46	50S ribosomal protein l27
Y592_05980	ENOG41087JC	Protein of unknown function (DUF464)
Y592_05985	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Y592_06000	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Y592_06005	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Y592_06010	ENOG4105MCT	stage V sporulation protein S
Y592_06020	ENOG4105CBJ	Metal-dependent enzyme
Y592_06025	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Y592_06030	ENOG4107R84	Peptidase dimerisation domain
Y592_06035	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Y592_06040	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Y592_06045	ENOG4105C3G	gtp-binding protein
Y592_06050	ENOG4105KC4	UPF0296 protein
Y592_06055	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Y592_06060	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
Y592_06080	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Y592_06095	ENOG4105CD3	dihydroorotase
Y592_06100	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Y592_06105	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Y592_06110	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Y592_06115	ENOG41081WB	50s ribosomal protein L10
Y592_06130	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Y592_06135	ENOG4105CDU	Replicative dna helicase
Y592_06160	ENOG4108Z5K	methylglyoxal synthase
Y592_06165	ENOG410667J	hydrolase
Y592_06175	ENOG4105C5S	asparaginyl-tRNA synthetase
Y592_06180	ENOG4105CTD	carboxy-peptidase
Y592_06195	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Y592_06205	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
Y592_06210	ENOG4107Y7Q	pfkb domain protein
Y592_06215	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Y592_06225	ENOG4108IUW	ABC transporter
Y592_06270	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
Y592_06275	ENOG4105CHR	reductase
Y592_06290	ENOG4107QIV	Cytochrome c biogenesis protein
Y592_06315	ENOG4108JU3	Alkyl hydroperoxide reductase
Y592_06335	ENOG4105MQ3	flagellar protein FliS
Y592_06350	ENOG4108JQ7	(ABC) transporter
Y592_06355	ENOG4105C3U	ABC transporter
Y592_06365	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Y592_06370	ENOG4107QSI	ABC, transporter
Y592_06375	ENOG4106H78	methyltransferase
Y592_06380	ENOG4105D38	putrescine abc transporter
Y592_06385	ENOG4105F38	ABC transporter, permease
Y592_06390	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Y592_06395	ENOG4107RUE	extracellular solute-binding protein family 1
Y592_06400	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Y592_06405	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Y592_06425	ENOG4108UQV	Membrane
Y592_06430	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Y592_06435	ENOG4105CTJ	Metal Dependent Phosphohydrolase
Y592_06440	ENOG4105C9A	Phoh family
Y592_06455	ENOG4107QSA	Oxaloacetate decarboxylase
Y592_06465	ENOG4107QX3	carboxylase
Y592_06470	ENOG4108ZVT	methylmalonyl-coA epimerase
Y592_06485	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Y592_06490	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Y592_06515	ENOG4107S1Q	Phosphatase
Y592_06525	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Y592_06530	ENOG4108ZC9	flagellar basal-body rod protein flgc
Y592_06535	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
Y592_06540	ENOG4107Y70	Heat shock protein
Y592_06545	ENOG4105CFG	Acts as a chaperone (By similarity)
Y592_06550	ENOG4105K8R	UPF0145 protein
Y592_06555	ENOG4105F6J	Alpha beta hydrolase fold
Y592_06565	ENOG4105DA5	(ABC) transporter
Y592_06570	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
Y592_06575	ENOG4105CHU	acetyl-coa acetyltransferase
Y592_06585	ENOG4107QP7	CoA-transferase subunit A
Y592_06590	ENOG4105BZ8	glutamate synthase
Y592_06595	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Y592_06605	ENOG4105DKQ	ROK family
Y592_06625	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Y592_06630	ENOG4105CBS	Chea signal transduction histidine kinase
Y592_06665	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Y592_06670	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Y592_06675	ENOG41081HM	2'-5' rna ligase
Y592_06680	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Y592_06685	ENOG410902V	Modulates RecA activity (By similarity)
Y592_06690	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Y592_06710	ENOG4108R86	Transcriptional regulator
Y592_06715	ENOG41084K4	Binds the 23S rRNA (By similarity)
Y592_06720	ENOG41060GV	RNA binding s1 domain protein
Y592_06725	ENOG4107QIZ	NADH dehydrogenase
Y592_06735	ENOG4107QIZ	NADH dehydrogenase
Y592_06745	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
Y592_06750	ENOG4105CCS	Glutamate formiminotransferase
Y592_06755	ENOG4105ECY	inositol monophosphatase
Y592_06760	ENOG4105CJN	penicillin-binding protein
Y592_06765	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Y592_06785	ENOG4105KTH	gatB Yqey
Y592_06790	ENOG41067B5	Histone deacetylase superfamily protein
Y592_06795	ENOG4108YZG	isomerase
Y592_06800	ENOG41082AN	stage II sporulation protein
Y592_06805	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Y592_06810	ENOG4106FU4	Archease protein family (MTH1598/TM1083)
Y592_06815	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Y592_06820	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Y592_06830	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Y592_06835	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Y592_06845	ENOG4108JQ7	(ABC) transporter
Y592_06850	ENOG4105CXT	aspartate transcarbamylase
Y592_06855	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Y592_06860	ENOG4105G5W	regulator Fur family
Y592_06865	ENOG4105D3R	alkyl hydroperoxide reductase
Y592_06870	ENOG4105VCQ	rubredoxin
Y592_06880	ENOG41090A1	ferritin
Y592_06890	ENOG4105MAX	Superoxide reductase
Y592_06895	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Y592_06910	ENOG4107104	thymidine kinase
Y592_06915	ENOG4105CGH	5'-nucleotidase
Y592_06925	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
Y592_06930	ENOG4105SC1	monovalent cation H antiporter subunit E
Y592_06935	ENOG410684G	monovalent cation H antiporter subunit F
Y592_06950	ENOG4105D65	subunit l
Y592_06955	ENOG4105MKQ	Monovalent cation H antiporter subunit C
Y592_06960	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Y592_06965	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Y592_06975	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Y592_06980	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Y592_06985	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Y592_06990	ENOG4105BZ8	glutamate synthase
Y592_07030	ENOG4105D1F	ATP-binding protein
Y592_07035	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Y592_07045	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Y592_07055	ENOG4105D7W	serine acetyltransferase
Y592_07060	ENOG4105C6T	cysteine synthase
Y592_07065	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Y592_07070	ENOG4105C8V	SAICAR synthetase
Y592_07075	ENOG4108A1T	Phosphoribosylformylglycinamidine synthase, purS
Y592_07080	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Y592_07085	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Y592_07100	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
Y592_07105	ENOG4108RE9	Phosphodiesterase
Y592_07110	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Y592_07115	ENOG4105CHM	Aminotransferase
Y592_07120	ENOG4105C83	adenylosuccinate lyase
Y592_07140	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Y592_07145	ENOG4105C87	Aminotransferase class I and II
Y592_07150	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Y592_07170	ENOG4105BZA	Phosphoglycerate kinase
Y592_07175	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Y592_07200	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Y592_07205	ENOG4105D2N	Aldolase
Y592_07225	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Y592_07230	ENOG4107QHF	type ii secretion system protein e
Y592_07240	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Y592_07245	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Y592_07250	ENOG4105KNE	Phosphatidate cytidylyltransferase
Y592_07255	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Y592_07260	ENOG4105DFF	Rod shape-determining protein mreb
Y592_07275	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Y592_07295	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Y592_07310	ENOG4105W00	Flagellar hook capping protein
Y592_07315	ENOG4105BZE	flagellar hook protein, FlgE
Y592_07320	ENOG41068WV	flagellar FlbD family protein
Y592_07325	ENOG4105E14	MotA TolQ exbB proton channel
Y592_07330	ENOG4107XSU	flagellar motor protein motb
Y592_07340	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Y592_07345	ENOG4105DD5	Flagellar motor switch protein
Y592_07355	ENOG4105C8J	)-transporter
Y592_07365	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Y592_07370	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Y592_07375	ENOG4105CJW	magnesium transporter
Y592_07385	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Y592_07390	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Y592_07405	ENOG4105E0A	ABC, transporter
Y592_07410	ENOG4107SC1	transglycosylase
Y592_07425	ENOG4105WPN	DNA integration recombination invertion protein
Y592_07430	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Y592_07435	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Y592_07450	ENOG4105C7W	Xanthine dehydrogenase
Y592_07455	ENOG4107YV9	domain protein
Y592_07475	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Y592_07490	ENOG4105C22	threonyL-tRNA synthetase
Y592_07495	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Y592_07505	ENOG4107QX8	SPFH domain, Band 7 family protein
Y592_07515	ENOG4105H20	Sporulation integral membrane protein YlbJ
Y592_07520	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Y592_07540	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Y592_07545	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Y592_07560	ENOG4107QQG	Dehydrogenase
Y592_07585	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Y592_07590	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Y592_07595	ENOG4105CPQ	Dehydrogenase
Y592_07600	ENOG4107QJQ	Mate efflux family protein
Y592_07610	ENOG4105DA5	(ABC) transporter
Y592_07630	ENOG4108IJ0	Aspartate ammonia-lyase
Y592_07635	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Y592_07655	ENOG4105DBI	uridine monophosphokinase
Y592_07660	ENOG4105DCI	Phosphohydrolase
Y592_07665	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Y592_07675	ENOG4108Z4T	Peptidase M50
Y592_07690	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Y592_07695	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Y592_07700	ENOG4105CHW	UPF0052 protein
Y592_07705	ENOG4105CIE	May be required for sporulation (By similarity)
Y592_07710	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Y592_07715	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Y592_07720	ENOG4105CRK	lysyL-tRNA synthetase
Y592_07730	ENOG41082I2	s4 domain protein
Y592_07740	ENOG4105BZ1	(ABC) transporter
Y592_07750	ENOG4105C3U	ABC transporter
Y592_07755	ENOG4108JQ7	(ABC) transporter
Y592_07770	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Y592_07805	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Y592_07810	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Y592_07815	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Y592_07820	ENOG4105CZX	twitching motility protein
Y592_07825	ENOG4105C6E	dna polymerase iii
Y592_07830	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Y592_07850	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Y592_07855	ENOG4105C4K	Nad synthetase
Y592_07875	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Y592_07880	ENOG4105E3H	phosphoglycerate mutase
Y592_07890	ENOG4105I3K	Ferric uptake regulator, Fur family
Y592_07895	ENOG4105CHV	Transcription elongation factor NusA
Y592_07900	ENOG4108396	Required for maturation of 30S ribosomal subunits (By similarity)
Y592_07925	ENOG4105D7B	Flagellar biosynthesis protein flha
Y592_07930	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Y592_07950	ENOG4107PHP	CheC --inhibitor of MCP methylation
Y592_07955	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Y592_07960	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Y592_07990	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Y592_08000	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Y592_08005	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Y592_08010	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Y592_08015	ENOG4105VG1	fes assembly suf system protein
Y592_08020	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Y592_08025	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Y592_08035	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Y592_08050	ENOG4105EJ9	Membrane
Y592_08055	ENOG4105MA4	psp1 domain protein
Y592_08065	ENOG4105K8N	protein family UPF0079, ATPase
Y592_08070	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Y592_08075	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Y592_08085	ENOG4105BZU	Histidine kinase
Y592_08090	ENOG4108HU6	Metal dependent phosphohydrolase
Y592_08095	ENOG41084NJ	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Y592_08105	ENOG4107V1F	Flagellar hook-associated 2 domain-containing protein
Y592_08125	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Y592_08135	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Y592_08140	ENOG4105CCT	upf0313 protein
Y592_08145	ENOG4105C37	(CBS) domain
Y592_08165	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Y592_08175	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Y592_08180	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Y592_08195	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Y592_08200	ENOG4105DXN	mazG family
Y592_08205	ENOG4107WSY	Domain of unknown function DUF20
Y592_08230	ENOG4105C0B	DNA polymerase III (alpha subunit)
Y592_08235	ENOG4105DJV	ribulose-phosphate 3-epimerase
Y592_08240	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Y592_08245	ENOG4107XI1	DHH family
Y592_08255	ENOG4105D4A	Cell wall formation (By similarity)
Y592_08260	ENOG4105DFM	M18 family aminopeptidase
Y592_08285	ENOG4105DG6	mannose-6-phosphate isomerase
Y592_08295	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Y592_08300	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Y592_08305	ENOG4105DFA	alanine racemase domain protein
Y592_08315	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Y592_08320	ENOG4105QGT	Phosphate uptake regulator
Y592_08330	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Y592_08335	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Y592_08345	ENOG4105D00	flagellar biosynthetic protein flhB
Y592_08355	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Y592_08360	ENOG4107U53	septum site-determining protein minD
Y592_08385	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Y592_08405	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Y592_08410	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Y592_08415	ENOG4108KGH	TRANSCRIPTIONal
Y592_08420	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Y592_08430	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Y592_08445	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Y592_08450	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Y592_08455	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Y592_08460	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Y592_08475	ENOG4108IUK	alpha amylase, catalytic
Y592_08480	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
Y592_08485	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Y592_08495	ENOG4108J9M	Transporter
Y592_08505	ENOG4105DGN	Electron transport complex
Y592_08510	ENOG4105DZB	Electron transport complex
Y592_08520	ENOG4105D6A	Electron transport complex
Y592_08525	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
Y592_08535	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Y592_08540	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Y592_08550	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Y592_08555	ENOG4105N5T	Radical SAM Protein
Y592_08560	ENOG4108IUW	ABC transporter
Y592_08565	ENOG4108KYE	ABC-2 type transporter
Y592_08575	ENOG4105C4X	radical SAM domain protein
Y592_08615	ENOG4105BZ1	(ABC) transporter
Y592_08645	ENOG4105BZ1	(ABC) transporter
Y592_08765	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
Y592_08780	ENOG4107ZCS	Phosphomethylpyrimidine kinase
Y592_08785	ENOG4105CTQ	phosphohexokinase
Y592_08795	ENOG4107QW8	radical SAM domain protein
Y592_08815	ENOG4107QHI	-hydrogenase
Y592_08830	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Y592_08835	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Y592_08840	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Y592_08845	ENOG4105CJR	Integral membrane protein (MviN
Y592_08850	ENOG4108R3D	Electron transport complex
Y592_08855	ENOG4105C79	DNA protecting protein DprA
Y592_08860	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Y592_08870	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Y592_08875	ENOG4105C1V	Peptidase, M16
Y592_08885	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Y592_08890	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Y592_08895	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
Y592_08900	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Y592_08905	ENOG4105C9M	aspartyl-trna synthetase
Y592_08910	ENOG41084GC	stage II sporulation protein
Y592_08915	ENOG4107RB4	Cytidine monophosphate kinase
Y592_08920	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Y592_08925	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Y592_08930	ENOG4105DIH	basic membrane
Y592_08940	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Y592_08945	ENOG41085QA	50S ribosomal protein l34
Y592_08950	ENOG41084AH	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Y592_08955	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Y592_08960	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Y592_08980	ENOG4105C5F	glutamine synthetase
Y592_08985	ENOG4105BZU	Histidine kinase
Y592_08995	ENOG4105CS2	ec 3.2.1.21
Y592_09015	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Y592_09060	ENOG4108EKI	Dehydrogenase
Y592_09085	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Y592_09120	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
Y592_09180	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Y592_09190	ENOG4107S85	alpha-2-macroglobulin domain protein
Y592_09200	ENOG4108QJJ	Protein of unknown function (DUF1175)
Y592_09210	ENOG4105EMU	Dehydrogenase
Y592_09215	ENOG4105EJ9	Membrane
Y592_09220	ENOG4107QSE	Dipeptidase
Y592_09245	ENOG4108IJ9	(ABC) transporter
Y592_09250	ENOG4105IRK	Glycosyl transferase (Group 1