locus-tag	class	description
IMZ38_00015	COG0546	phosphoglycolate phosphatase activity
IMZ38_00020	COG0561	phosphatase activity
IMZ38_00025	COG0493	'glutamate synthase
IMZ38_00025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMZ38_00030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMZ38_00035	COG0651	ATP synthesis coupled electron transport
IMZ38_00040	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMZ38_00055	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IMZ38_00055	COG3261	NADH dehydrogenase
IMZ38_00060	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMZ38_00065	COG3260	NADH ubiquinone oxidoreductase 20
IMZ38_00085	COG1185	polyribonucleotide nucleotidyltransferase activity
IMZ38_00135	COG1185	polyribonucleotide nucleotidyltransferase activity
IMZ38_00160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMZ38_00190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMZ38_00195	COG2890	protein-(glutamine-N5) methyltransferase activity
IMZ38_00200	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IMZ38_00210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMZ38_00245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IMZ38_00265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMZ38_00275	COG1162	GTPase activity
IMZ38_00285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMZ38_00290	COG1115	amino acid carrier protein
IMZ38_00315	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IMZ38_00335	COG0668	transmembrane transport
IMZ38_00350	COG0085	RNA polymerase activity
IMZ38_00355	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMZ38_00360	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMZ38_00385	COG0049	tRNA binding
IMZ38_00405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMZ38_00410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMZ38_00415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMZ38_00430	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMZ38_00435	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMZ38_00445	COG0052	Belongs to the universal ribosomal protein uS2 family
IMZ38_00450	COG1355	regulation of microtubule-based process
IMZ38_00455	COG1304	FMN binding
IMZ38_00550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMZ38_00555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMZ38_00605	COG3842	ATPase activity
IMZ38_00675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMZ38_00715	COG0012	GTP binding
IMZ38_00755	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ38_00770	COG1185	polyribonucleotide nucleotidyltransferase activity
IMZ38_00775	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IMZ38_00780	COG1185	polyribonucleotide nucleotidyltransferase activity
IMZ38_00810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMZ38_00825	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IMZ38_00835	COG0417	DNA replication proofreading
IMZ38_00860	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IMZ38_00870	COG0864	Transcriptional regulator
IMZ38_00905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMZ38_00910	COG0719	Fe-S assembly protein
IMZ38_00915	COG0719	Fe-S assembly protein
IMZ38_00920	COG0396	ATPase activity
IMZ38_00925	COG2182	Extracellular solute-binding protein
IMZ38_00930	COG1175	transmembrane transport
IMZ38_00935	COG3833	ABC-type maltose transport systems, permease component
IMZ38_00940	COG3842	ATPase activity
IMZ38_00980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IMZ38_00990	COG0492	ferredoxin-NADP+ reductase activity
IMZ38_00995	COG0667	Aldo Keto reductase
IMZ38_01005	COG0270	DNA (cytosine-5-)-methyltransferase activity
IMZ38_01025	COG0459	protein refolding
IMZ38_01030	COG0433	COG0433 Predicted ATPase
IMZ38_01065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMZ38_01075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMZ38_01140	COG0297	glycogen (starch) synthase activity
IMZ38_01150	COG0438	transferase activity, transferring glycosyl groups
IMZ38_01165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMZ38_01170	COG0438	transferase activity, transferring glycosyl groups
IMZ38_01190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMZ38_01205	COG1013	pyruvate-flavodoxin oxidoreductase activity
IMZ38_01210	COG0674	pyruvate-flavodoxin oxidoreductase activity
IMZ38_01210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IMZ38_01225	COG1592	Rubrerythrin
IMZ38_01230	COG0778	Nitroreductase
IMZ38_01230	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IMZ38_01245	COG2223	nitrite transmembrane transporter activity
IMZ38_01265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMZ38_01270	COG0430	RNA-3'-phosphate cyclase activity
IMZ38_01280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IMZ38_01285	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IMZ38_01295	COG1047	Peptidyl-prolyl cis-trans
IMZ38_01300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMZ38_01335	COG1129	ABC transporter
IMZ38_01340	COG1980	fructose-bisphosphate aldolase activity
IMZ38_01345	COG0149	triose-phosphate isomerase activity
IMZ38_01405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IMZ38_01410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMZ38_01440	COG1110	DNA topoisomerase II activity
IMZ38_01500	COG2267	carboxylic ester hydrolase activity
IMZ38_01510	COG1918	ferrous iron import across plasma membrane
IMZ38_01510	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IMZ38_01540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMZ38_01675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMZ38_01700	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IMZ38_01750	COG0003	Pfam Anion-transporting ATPase
IMZ38_01795	COG0419	ATPase involved in DNA repair
IMZ38_01810	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IMZ38_01820	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IMZ38_01850	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IMZ38_01870	COG0674	pyruvate-flavodoxin oxidoreductase activity
IMZ38_01945	COG1201	RNA secondary structure unwinding
IMZ38_01980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMZ38_01990	COG0089	rRNA binding
IMZ38_01995	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMZ38_02010	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMZ38_02015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMZ38_02020	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMZ38_02025	COG0255	Belongs to the universal ribosomal protein uL29 family
IMZ38_02035	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMZ38_02040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMZ38_02055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMZ38_02065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMZ38_02090	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMZ38_02100	COG0200	Binds to the 23S rRNA
IMZ38_02120	COG0563	adenylate kinase activity
IMZ38_02135	COG2813	Specifically methylates the guanine in position
IMZ38_02170	COG1342	Belongs to the UPF0251 family
IMZ38_02205	COG1850	ribulose-bisphosphate carboxylase activity
IMZ38_02225	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMZ38_02285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMZ38_02290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IMZ38_02295	COG1111	helicase
IMZ38_02295	COG1205	dead DEAH box helicase
IMZ38_02310	COG1489	DNA binding
IMZ38_02320	COG0717	Belongs to the dCTP deaminase family
IMZ38_02325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMZ38_02335	COG0395	ABC-type sugar transport system, permease component
IMZ38_02345	COG1653	transport
IMZ38_02420	COG0552	protein localization to endoplasmic reticulum
IMZ38_02435	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMZ38_02455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMZ38_02465	COG1953	Uracil, thiamine, allantoin
IMZ38_02505	COG0601	transmembrane transport
IMZ38_02510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMZ38_02515	COG0444	Belongs to the ABC transporter superfamily
IMZ38_02520	COG4608	Belongs to the ABC transporter superfamily
IMZ38_02530	COG0471	metal ion transport
IMZ38_02550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMZ38_02630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMZ38_02640	COG1131	(ABC) transporter
IMZ38_02655	COG0585	pseudouridine synthase activity
IMZ38_02680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMZ38_02700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IMZ38_02715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMZ38_02725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMZ38_02725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMZ38_02755	COG1418	mRNA catabolic process
IMZ38_02770	COG0525	valine-tRNA ligase activity
IMZ38_02775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IMZ38_02775	COG1796	DNA polymerase
IMZ38_02795	COG0189	ligase activity
IMZ38_02810	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IMZ38_02815	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IMZ38_02835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMZ38_02875	COG0651	ATP synthesis coupled electron transport
IMZ38_02880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMZ38_02885	COG0649	NAD binding
IMZ38_02920	COG1863	multisubunit Na H antiporter MnhE subunit
IMZ38_02935	COG1899	peptidyl-lysine modification to peptidyl-hypusine
IMZ38_03010	COG0714	Associated with various cellular activities
IMZ38_03045	COG1515	deoxyribonuclease V activity
IMZ38_03130	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMZ38_03150	COG1324	tolerance protein
IMZ38_03165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMZ38_03185	COG0142	geranyltranstransferase activity
IMZ38_03200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMZ38_03215	COG1121	(ABC) transporter
IMZ38_03220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ38_03225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ38_03240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMZ38_03265	COG0215	cysteine-tRNA ligase activity
IMZ38_03270	COG0813	purine-nucleoside phosphorylase activity
IMZ38_03305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMZ38_03310	COG0156	8-amino-7-oxononanoate synthase activity
IMZ38_03325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMZ38_03405	COG1175	transmembrane transport
IMZ38_03410	COG0395	ABC-type sugar transport system, permease component
IMZ38_03415	COG3842	ATPase activity
IMZ38_03420	COG3842	ATPase activity
IMZ38_03440	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMZ38_03445	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMZ38_03450	COG3845	ABC transporter
IMZ38_03455	COG1744	ABC transporter substrate-binding protein PnrA-like
IMZ38_03465	COG5006	permease, DMT superfamily
IMZ38_03500	COG0306	phosphate transporter
IMZ38_03510	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IMZ38_03515	COG0006	proline dipeptidase activity
IMZ38_03530	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IMZ38_03535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMZ38_03580	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMZ38_03645	COG0504	CTP synthase activity
IMZ38_03660	COG0667	Aldo Keto reductase
IMZ38_03680	COG0023	Translation Initiation Factor
IMZ38_03690	COG0010	Belongs to the arginase family
IMZ38_03710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMZ38_03730	COG0163	prenyltransferase activity
IMZ38_03750	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMZ38_03765	COG1110	DNA topoisomerase II activity
IMZ38_03770	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
IMZ38_03775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMZ38_03780	COG1444	tRNA N-acetyltransferase activity
IMZ38_03785	COG1486	melibiose metabolic process
IMZ38_03800	COG2414	aldehyde ferredoxin oxidoreductase
IMZ38_03815	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
IMZ38_03820	COG0009	L-threonylcarbamoyladenylate synthase
IMZ38_03835	COG1404	Belongs to the peptidase S8 family
IMZ38_03840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMZ38_03845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMZ38_03850	COG0534	Mate efflux family protein
IMZ38_03985	COG0432	Pfam Uncharacterised protein family UPF0047
IMZ38_04010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ38_04010	COG1042	CoA-binding domain protein
IMZ38_04010	COG0045	succinate-CoA ligase (ADP-forming) activity
IMZ38_04015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ38_04015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ38_04020	COG0301	tRNA thio-modification
IMZ38_04050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMZ38_04050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMZ38_04065	COG1414	Transcriptional regulator
IMZ38_04100	COG0656	L-ascorbic acid biosynthetic process
IMZ38_04115	COG0563	adenylate kinase activity
IMZ38_04130	COG0017	Asparaginyl-tRNA synthetase
IMZ38_04145	COG0601	transmembrane transport
IMZ38_04155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMZ38_04160	COG0444	Belongs to the ABC transporter superfamily
IMZ38_04165	COG4608	Belongs to the ABC transporter superfamily
IMZ38_04170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMZ38_04190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ38_04220	COG1201	RNA secondary structure unwinding
IMZ38_04230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IMZ38_04250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMZ38_04255	COG2151	metal-sulfur cluster biosynthetic enzyme
IMZ38_04265	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IMZ38_04280	COG1988	membrane-bound metal-dependent
IMZ38_04285	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IMZ38_04290	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IMZ38_04310	COG0436	Aminotransferase
IMZ38_04335	COG1702	phosphate starvation-inducible protein PhoH
IMZ38_04340	COG2264	protein methyltransferase activity
IMZ38_04345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMZ38_04350	COG0017	Asparaginyl-tRNA synthetase
IMZ38_04360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMZ38_04380	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IMZ38_04400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMZ38_04415	COG1131	(ABC) transporter
IMZ38_04430	COG3281	Trehalose synthase
IMZ38_04440	COG1449	Belongs to the glycosyl hydrolase 57 family
IMZ38_04445	COG0297	glycogen (starch) synthase activity
IMZ38_04455	COG2404	hydrolase activity, acting on ester bonds
IMZ38_04470	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IMZ38_04490	COG1006	Multisubunit Na H antiporter MnhC subunit
IMZ38_04520	COG0649	NAD binding
IMZ38_04530	COG3260	NADH ubiquinone oxidoreductase 20
IMZ38_04535	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IMZ38_04565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMZ38_04590	COG3842	ATPase activity
IMZ38_04605	COG1058	Belongs to the CinA family
IMZ38_04605	COG1546	Belongs to the CinA family
IMZ38_04620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMZ38_04625	COG0521	Mo-molybdopterin cofactor biosynthetic process
IMZ38_04630	COG1011	Hydrolase
IMZ38_04655	COG0405	Gamma-glutamyltransferase
IMZ38_04660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMZ38_04665	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
IMZ38_04690	COG1469	GTP cyclohydrolase I activity
IMZ38_04700	COG2033	superoxide reductase activity
IMZ38_04710	COG1522	sequence-specific DNA binding
IMZ38_04720	COG0426	domain, Protein
IMZ38_04725	COG0450	alkyl hydroperoxide reductase
IMZ38_04735	COG1078	dGTPase activity
IMZ38_04745	COG1830	Aldolase
IMZ38_04750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMZ38_04765	COG0295	cytidine deaminase activity
IMZ38_04770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMZ38_04775	COG0463	Glycosyl transferase, family 2
IMZ38_04785	COG3845	ABC transporter
IMZ38_04795	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMZ38_04800	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IMZ38_04810	COG0495	leucyl-tRNA aminoacylation
IMZ38_04815	COG0719	Fe-S assembly protein
IMZ38_04820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMZ38_04825	COG2095	MarC family integral membrane protein
IMZ38_04840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMZ38_04850	COG0439	Biotin carboxylase
IMZ38_04855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMZ38_04855	COG0574	Belongs to the PEP-utilizing enzyme family
IMZ38_04875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMZ38_04880	COG0235	Class ii aldolase
IMZ38_04890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMZ38_04895	COG1085	galactose-1-phosphate uridylyltransferase
IMZ38_04905	COG2814	Major facilitator Superfamily
IMZ38_04940	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IMZ38_04945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMZ38_04950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMZ38_04955	COG1522	sequence-specific DNA binding
IMZ38_04960	COG0174	glutamine synthetase
IMZ38_04970	COG2267	carboxylic ester hydrolase activity
IMZ38_05000	COG4149	molybdate abc transporter
IMZ38_05005	COG3842	ATPase activity
IMZ38_05045	COG0409	Hydrogenase expression formation protein
IMZ38_05050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMZ38_05055	COG1166	arginine decarboxylase activity
IMZ38_05100	COG0864	Transcriptional regulator
IMZ38_05125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMZ38_05130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ38_05130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ38_05135	COG1940	carbohydrate kinase activity
IMZ38_05145	COG1446	asparaginase
IMZ38_05155	COG2059	Chromate
IMZ38_05160	COG0312	modulator of DNA gyrase
IMZ38_05255	COG0037	tRNA processing
IMZ38_05275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMZ38_05280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMZ38_05285	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IMZ38_05290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMZ38_05300	COG0018	arginyl-trna synthetase
IMZ38_05315	COG0330	HflC and HflK could
IMZ38_05335	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMZ38_05355	COG1122	ATPase activity
IMZ38_05390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ38_05420	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IMZ38_05420	COG3608	succinylglutamate desuccinylase aspartoacylase
IMZ38_05435	COG0714	Associated with various cellular activities
IMZ38_05470	COG0511	ligase activity, forming carbon-carbon bonds
IMZ38_05475	COG0733	neurotransmitter:sodium symporter activity
IMZ38_05490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMZ38_05490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMZ38_05495	COG0306	phosphate transporter
IMZ38_05500	COG1363	Peptidase, m42
IMZ38_05510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMZ38_05515	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMZ38_05520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMZ38_05525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMZ38_05530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMZ38_05535	COG0509	glycine decarboxylation via glycine cleavage system
IMZ38_05545	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IMZ38_05555	COG1131	(ABC) transporter
IMZ38_05565	COG1136	(ABC) transporter
IMZ38_05575	COG0577	efflux transmembrane transporter activity
IMZ38_05575	COG1136	(ABC) transporter
IMZ38_05605	COG1013	pyruvate-flavodoxin oxidoreductase activity
IMZ38_05610	COG0674	pyruvate-flavodoxin oxidoreductase activity
IMZ38_05610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IMZ38_05620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IMZ38_05630	COG0674	pyruvate-flavodoxin oxidoreductase activity
IMZ38_05635	COG1013	pyruvate-flavodoxin oxidoreductase activity
IMZ38_05645	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMZ38_05645	COG1902	pentaerythritol trinitrate reductase activity
IMZ38_05650	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IMZ38_05655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMZ38_05665	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IMZ38_05670	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IMZ38_05675	COG0445	tRNA wobble uridine modification
IMZ38_05765	COG1994	Peptidase M50
IMZ38_05785	COG0312	modulator of DNA gyrase
IMZ38_05790	COG0312	modulator of DNA gyrase
IMZ38_05800	COG1122	ATPase activity
IMZ38_05815	COG0534	Mate efflux family protein
IMZ38_05820	COG1131	(ABC) transporter
IMZ38_05835	COG0546	phosphoglycolate phosphatase activity
IMZ38_05840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMZ38_05885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMZ38_05890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMZ38_05915	COG2894	cell division
IMZ38_05920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMZ38_05925	COG4581	dead DEAH box helicase
IMZ38_05930	COG0303	'Molybdopterin
IMZ38_05960	COG4152	abc transporter atp-binding protein
IMZ38_05980	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMZ38_05985	COG0489	protein tyrosine kinase activity
IMZ38_06005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMZ38_06015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMZ38_06020	COG1115	amino acid carrier protein
IMZ38_06055	COG0167	dihydroorotate dehydrogenase activity
IMZ38_06060	COG0126	phosphoglycerate kinase activity
IMZ38_06070	COG0589	response to stress
IMZ38_06075	COG0058	SHG alpha-glucan phosphorylase activity
IMZ38_06085	COG0072	phenylalanine-tRNA ligase activity
IMZ38_06100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMZ38_06100	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IMZ38_06115	COG0444	Belongs to the ABC transporter superfamily
IMZ38_06120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMZ38_06125	COG0601	transmembrane transport
IMZ38_06130	COG0747	negative chemotaxis
IMZ38_06135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMZ38_06145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IMZ38_06155	COG1528	Iron-storage protein
IMZ38_06160	COG2309	aminopeptidase activity
IMZ38_06170	COG1122	ATPase activity
IMZ38_06195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IMZ38_06225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMZ38_06240	COG5183	chlorophyll binding
IMZ38_06240	COG2133	pyrroloquinoline quinone binding
IMZ38_06250	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IMZ38_06270	COG3845	ABC transporter
IMZ38_06275	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMZ38_06280	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMZ38_06285	COG1063	alcohol dehydrogenase
IMZ38_06320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMZ38_06335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IMZ38_06430	COG0501	Belongs to the peptidase M48B family
IMZ38_06460	COG1793	dna ligase
IMZ38_06470	COG1573	uracil-dna glycosylase
IMZ38_06495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IMZ38_06515	COG0516	GMP reductase activity
IMZ38_06550	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
IMZ38_06570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMZ38_06595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMZ38_06610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMZ38_06615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMZ38_06630	COG1222	aaa ATPase
IMZ38_06650	COG0148	phosphopyruvate hydratase activity
IMZ38_06670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMZ38_06670	COG0551	DNA topoisomerase type I activity
IMZ38_06685	COG0459	protein refolding
IMZ38_06720	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMZ38_06730	COG1757	Na H antiporter
IMZ38_06755	COG1618	nucleotide phosphatase activity, acting on free nucleotides
IMZ38_06760	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
IMZ38_06800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMZ38_06840	COG1234	tRNA 3'-trailer cleavage
IMZ38_06855	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IMZ38_06890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IMZ38_06910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IMZ38_06930	COG2414	aldehyde ferredoxin oxidoreductase
IMZ38_06945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMZ38_06955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMZ38_06960	COG1012	belongs to the aldehyde dehydrogenase family
IMZ38_06970	COG2414	aldehyde ferredoxin oxidoreductase
IMZ38_06990	COG0493	'glutamate synthase
IMZ38_06990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMZ38_06995	COG0543	2 iron, 2 sulfur cluster binding
IMZ38_07030	COG2212	antiporter activity
IMZ38_07035	COG1320	monovalent cation:proton antiporter activity
IMZ38_07050	COG1006	Multisubunit Na H antiporter MnhC subunit
IMZ38_07055	COG1863	multisubunit Na H antiporter MnhE subunit
IMZ38_07060	COG0651	ATP synthesis coupled electron transport
IMZ38_07110	COG0494	nUDIX hydrolase
IMZ38_07145	COG0494	nUDIX hydrolase
IMZ38_07155	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IMZ38_07155	COG0517	IMP dehydrogenase activity
IMZ38_07160	COG1394	ATPase activity, coupled to movement of substances
IMZ38_07200	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
IMZ38_07225	COG0442	prolyl-tRNA aminoacylation
IMZ38_07240	COG4974	Belongs to the 'phage' integrase family
IMZ38_07270	COG2222	sugar isomerase
IMZ38_07280	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate