locus-tag	class	description
KDW03_00005	COG1785	Belongs to the alkaline phosphatase family
KDW03_00015	COG0129	dihydroxy-acid dehydratase activity
KDW03_00025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KDW03_00035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KDW03_00050	COG0194	GDP metabolic process
KDW03_00055	COG1561	YicC-like family, N-terminal region
KDW03_00060	COG0571	ribonuclease III activity
KDW03_00065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KDW03_00070	COG1028	Short-chain dehydrogenase reductase Sdr
KDW03_00075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KDW03_00080	COG0416	fatty acid biosynthetic process
KDW03_00085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KDW03_00100	COG0366	Alpha amylase catalytic
KDW03_00100	COG1874	Beta-galactosidase
KDW03_00105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KDW03_00110	COG0473	3-isopropylmalate dehydrogenase activity
KDW03_00205	COG2801	Transposase and inactivated derivatives
KDW03_00230	COG2801	Transposase and inactivated derivatives
KDW03_00250	COG0534	Mate efflux family protein
KDW03_00265	COG0446	pyridine nucleotide-disulphide oxidoreductase
KDW03_00270	COG3850	Histidine kinase
KDW03_00270	COG5002	protein histidine kinase activity
KDW03_00285	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KDW03_00310	COG1408	metallophosphoesterase
KDW03_00320	COG0275	rRNA processing
KDW03_00350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KDW03_00370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KDW03_00390	COG0497	DNA recombination
KDW03_00395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KDW03_00420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KDW03_00425	COG0612	Peptidase, M16
KDW03_00430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KDW03_00465	COG2801	Transposase and inactivated derivatives
KDW03_00475	COG2801	Transposase and inactivated derivatives
KDW03_00480	COG0038	chloride channel
KDW03_00490	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KDW03_00515	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KDW03_00535	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KDW03_00555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KDW03_00640	COG2801	Transposase and inactivated derivatives
KDW03_00645	COG0438	transferase activity, transferring glycosyl groups
KDW03_00650	COG0779	Required for maturation of 30S ribosomal subunits
KDW03_00655	COG0195	Participates in both transcription termination and antitermination
KDW03_00660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KDW03_00665	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KDW03_00670	COG2404	hydrolase activity, acting on ester bonds
KDW03_00700	COG1480	7TM receptor with intracellular HD hydrolase
KDW03_00705	COG1702	phosphate starvation-inducible protein PhoH
KDW03_00725	COG0643	Histidine kinase
KDW03_00725	COG2198	Histidine kinase
KDW03_00730	COG0840	transmembrane signaling receptor activity
KDW03_00740	COG0835	chemotaxis
KDW03_00750	COG2201	protein-glutamate methylesterase activity
KDW03_00755	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KDW03_00760	COG0745	RESPONSE REGULATOR receiver
KDW03_00775	COG0745	RESPONSE REGULATOR receiver
KDW03_00790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KDW03_00795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KDW03_00800	COG1032	radical SAM domain protein
KDW03_00810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KDW03_00815	COG0750	zinc metalloprotease
KDW03_00825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KDW03_00840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KDW03_00845	COG2801	Transposase and inactivated derivatives
KDW03_00870	COG2801	Transposase and inactivated derivatives
KDW03_00885	COG0217	transcriptional regulatory protein
KDW03_00900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KDW03_00910	COG4191	Histidine kinase
KDW03_00920	COG2801	Transposase and inactivated derivatives
KDW03_00935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KDW03_00945	COG0402	S-adenosylhomocysteine deaminase activity
KDW03_00950	COG2208	phosphoserine phosphatase activity
KDW03_01020	COG0312	modulator of DNA gyrase
KDW03_01025	COG2738	Putative neutral zinc metallopeptidase
KDW03_01030	COG0772	Belongs to the SEDS family
KDW03_01035	COG0768	penicillin binding
KDW03_01040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KDW03_01045	COG1573	uracil-dna glycosylase
KDW03_01050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KDW03_01060	COG2957	Belongs to the agmatine deiminase family
KDW03_01065	COG1362	aminopeptidase activity
KDW03_01090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KDW03_01110	COG0527	aspartate kinase activity
KDW03_01115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KDW03_01120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KDW03_01125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KDW03_01140	COG0426	domain, Protein
KDW03_01145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KDW03_01145	COG1773	rubredoxin
KDW03_01150	COG0730	response to heat
KDW03_01195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KDW03_01205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KDW03_01230	COG0280	phosphate acetyltransferase
KDW03_01235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KDW03_01280	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KDW03_01295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KDW03_01300	COG1131	(ABC) transporter
KDW03_01310	COG1725	Transcriptional regulator
KDW03_01315	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KDW03_01325	COG1191	sigma factor activity
KDW03_01370	COG0366	Alpha amylase catalytic
KDW03_01395	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
KDW03_01415	COG0028	Belongs to the TPP enzyme family
KDW03_01420	COG0440	acetolactate synthase activity
KDW03_01425	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KDW03_01480	COG1516	flagellar protein fliS
KDW03_01500	COG0446	pyridine nucleotide-disulphide oxidoreductase
KDW03_01505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KDW03_01505	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KDW03_01510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KDW03_01520	COG0662	Cupin 2, conserved barrel domain protein
KDW03_01520	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KDW03_01540	COG0616	signal peptide processing
KDW03_01550	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KDW03_01555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KDW03_01560	COG3956	TIGRFAM MazG family protein
KDW03_01735	COG2369	cell adhesion
KDW03_01760	COG0395	ABC-type sugar transport system, permease component
KDW03_01765	COG1175	transmembrane transport
KDW03_01770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KDW03_01775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KDW03_01795	COG0312	modulator of DNA gyrase
KDW03_01805	COG2255	four-way junction helicase activity
KDW03_01810	COG0629	single-stranded DNA binding
KDW03_01840	COG0463	Glycosyl transferase, family 2
KDW03_01845	COG0285	dihydrofolate synthase activity
KDW03_01855	COG0835	chemotaxis
KDW03_01860	COG2801	Transposase and inactivated derivatives
KDW03_01865	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KDW03_02055	COG1475	DNA binding
KDW03_02200	COG2801	Transposase and inactivated derivatives
KDW03_02220	COG0840	transmembrane signaling receptor activity
KDW03_02230	COG3328	transposase activity
KDW03_02235	COG0166	Belongs to the GPI family
KDW03_02240	COG1490	D-aminoacyl-tRNA deacylase activity
KDW03_02245	COG0037	tRNA processing
KDW03_02250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KDW03_02255	COG2801	Transposase and inactivated derivatives
KDW03_02265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KDW03_02275	COG1615	UPF0182 protein
KDW03_02285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KDW03_02310	COG1242	4 iron, 4 sulfur cluster binding
KDW03_02315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KDW03_02330	COG0149	triose-phosphate isomerase activity
KDW03_02335	COG0126	phosphoglycerate kinase activity
KDW03_02390	COG0542	response to heat
KDW03_02425	COG0706	membrane insertase activity
KDW03_02435	COG0101	tRNA pseudouridine synthase activity
KDW03_02465	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KDW03_02470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KDW03_02480	COG0288	reversible hydration of carbon dioxide
KDW03_02490	COG2204	response regulator
KDW03_02505	COG0574	Belongs to the PEP-utilizing enzyme family
KDW03_02505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KDW03_02520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KDW03_02540	COG0848	biopolymer transport protein
KDW03_02570	COG0210	DNA helicase
KDW03_02580	COG0072	phenylalanine-tRNA ligase activity
KDW03_02585	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KDW03_02600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KDW03_02615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KDW03_02620	COG0133	tryptophan synthase activity
KDW03_02625	COG0673	inositol 2-dehydrogenase activity
KDW03_02630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KDW03_02635	COG0085	RNA polymerase activity
KDW03_02640	COG0222	ribosome binding
KDW03_02650	COG0081	regulation of translation
KDW03_02660	COG0250	Participates in transcription elongation, termination and antitermination
KDW03_02665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KDW03_02695	COG2843	Capsule synthesis protein
KDW03_02700	COG0165	Argininosuccinate lyase
KDW03_02705	COG0538	isocitrate dehydrogenase activity
KDW03_02745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KDW03_02750	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KDW03_02765	COG0067	glutamate synthase
KDW03_02780	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KDW03_02790	COG0792	nuclease activity
KDW03_02805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KDW03_02810	COG0543	2 iron, 2 sulfur cluster binding
KDW03_02825	COG2801	Transposase and inactivated derivatives
KDW03_02845	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KDW03_02845	COG2199	diguanylate cyclase activity
KDW03_02865	COG2801	Transposase and inactivated derivatives
KDW03_02870	COG2801	Transposase and inactivated derivatives
KDW03_02890	COG0629	single-stranded DNA binding
KDW03_02895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KDW03_02905	COG0359	binds to the 23S rRNA
KDW03_02910	COG0305	Participates in initiation and elongation during chromosome replication
KDW03_02915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KDW03_02920	COG1127	ABC transporter
KDW03_02975	COG0009	L-threonylcarbamoyladenylate synthase
KDW03_02985	COG0534	Mate efflux family protein
KDW03_02990	COG0739	heme binding
KDW03_02990	COG0741	lytic transglycosylase activity
KDW03_02990	COG1196	nuclear chromosome segregation
KDW03_03000	COG0482	sulfurtransferase activity
KDW03_03005	COG0585	pseudouridine synthase activity
KDW03_03010	COG1523	belongs to the glycosyl hydrolase 13 family
KDW03_03015	COG4657	Part of a membrane complex involved in electron transport
KDW03_03020	COG4660	Part of a membrane complex involved in electron transport
KDW03_03025	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KDW03_03030	COG4658	electron transport chain
KDW03_03035	COG4656	Part of a membrane complex involved in electron transport
KDW03_03040	COG3842	ATPase activity
KDW03_03045	COG0237	dephospho-CoA kinase activity
KDW03_03065	COG1597	lipid kinase activity
KDW03_03075	COG1597	lipid kinase activity
KDW03_03110	COG1523	belongs to the glycosyl hydrolase 13 family
KDW03_03170	COG0741	lytic transglycosylase activity
KDW03_03200	COG2197	response regulator
KDW03_03210	COG2211	Major facilitator Superfamily
KDW03_03215	COG1994	Peptidase M50
KDW03_03235	COG0646	methionine synthase
KDW03_03235	COG1410	methionine synthase
KDW03_03240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KDW03_03250	COG1459	type II secretion system
KDW03_03255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KDW03_03260	COG2814	Major facilitator Superfamily
KDW03_03270	COG2246	polysaccharide biosynthetic process
KDW03_03275	COG0463	Glycosyl transferase, family 2
KDW03_03280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KDW03_03305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KDW03_03335	COG0463	Glycosyl transferase, family 2
KDW03_03335	COG1216	Glycosyl transferase, family 2
KDW03_03350	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KDW03_03355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KDW03_03370	COG1216	Glycosyl transferase, family 2
KDW03_03385	COG0438	transferase activity, transferring glycosyl groups
KDW03_03390	COG1215	transferase activity, transferring glycosyl groups
KDW03_03415	COG0297	glycogen (starch) synthase activity
KDW03_03430	COG1233	COG1233 Phytoene dehydrogenase and related
KDW03_03455	COG1321	iron dependent repressor
KDW03_03460	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KDW03_03460	COG1918	ferrous iron import across plasma membrane
KDW03_03465	COG0598	Magnesium transport protein CorA
KDW03_03485	COG0765	amino acid transport
KDW03_03530	COG2801	Transposase and inactivated derivatives
KDW03_03560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KDW03_03585	COG2827	Endonuclease containing a URI domain
KDW03_03590	COG4120	Belongs to the binding-protein-dependent transport system permease family
KDW03_03600	COG0372	Belongs to the citrate synthase family
KDW03_03610	COG1360	Flagellar Motor Protein
KDW03_03625	COG1749	Flagellar hook protein flgE
KDW03_03630	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KDW03_03680	COG2801	Transposase and inactivated derivatives
KDW03_03690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KDW03_03715	COG1125	glycine betaine transport
KDW03_03715	COG0517	IMP dehydrogenase activity
KDW03_03720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KDW03_03720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KDW03_03725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KDW03_03730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KDW03_03740	COG0351	phosphomethylpyrimidine kinase
KDW03_03740	COG0352	thiamine-phosphate diphosphorylase activity
KDW03_03745	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KDW03_03750	COG0826	peptidase U32
KDW03_03800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KDW03_03800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KDW03_03820	COG2022	thiamine diphosphate biosynthetic process
KDW03_03825	COG2252	PERMEase
KDW03_03830	COG1192	Involved in chromosome partitioning
KDW03_03835	COG1475	DNA binding
KDW03_03840	COG0436	Aminotransferase
KDW03_03855	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KDW03_03900	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KDW03_03905	COG0719	Fe-S assembly protein
KDW03_03910	COG0396	ATPase activity
KDW03_03915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KDW03_03920	COG0641	radical SAM
KDW03_03925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KDW03_03940	COG0745	RESPONSE REGULATOR receiver
KDW03_03945	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KDW03_03945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KDW03_03950	COG0540	Belongs to the ATCase OTCase family
KDW03_03960	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KDW03_04010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KDW03_04070	COG0731	radical SAM domain protein
KDW03_04075	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KDW03_04085	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KDW03_04090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KDW03_04095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KDW03_04095	COG0519	Catalyzes the synthesis of GMP from XMP
KDW03_04105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KDW03_04105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KDW03_04115	COG0366	Alpha amylase catalytic
KDW03_04120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KDW03_04125	COG0592	DNA-directed DNA polymerase activity
KDW03_04130	COG2801	Transposase and inactivated derivatives
KDW03_04135	COG1131	(ABC) transporter
KDW03_04155	COG0577	efflux transmembrane transporter activity
KDW03_04155	COG1136	(ABC) transporter
KDW03_04215	COG2801	Transposase and inactivated derivatives
KDW03_04265	COG1595	DNA-templated transcription, initiation
KDW03_04275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KDW03_04285	COG1085	galactose-1-phosphate uridylyltransferase
KDW03_04290	COG1959	2 iron, 2 sulfur cluster binding
KDW03_04325	COG0745	RESPONSE REGULATOR receiver
KDW03_04345	COG0785	Cytochrome C biogenesis protein
KDW03_04370	COG3328	transposase activity
KDW03_04390	COG5000	phosphorelay sensor kinase activity
KDW03_04395	COG2204	response regulator
KDW03_04405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KDW03_04410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KDW03_04410	COG0140	phosphoribosyl-ATP diphosphatase activity
KDW03_04415	COG2204	response regulator
KDW03_04430	COG2801	Transposase and inactivated derivatives
KDW03_04440	COG0525	valine-tRNA ligase activity
KDW03_04465	COG0758	DNA mediated transformation
KDW03_04465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KDW03_04480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KDW03_04480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KDW03_04495	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KDW03_04510	COG2801	Transposase and inactivated derivatives
KDW03_04545	COG2801	Transposase and inactivated derivatives
KDW03_04550	COG0569	domain protein
KDW03_04555	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KDW03_04560	COG2885	chlorophyll binding
KDW03_04585	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KDW03_04595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KDW03_04600	COG0537	adenosine 5'-monophosphoramidase activity
KDW03_04610	COG0511	ligase activity, forming carbon-carbon bonds
KDW03_04615	COG2199	diguanylate cyclase activity
KDW03_04615	COG2200	EAL domain
KDW03_04615	COG3287	FIST C domain
KDW03_04635	COG2801	Transposase and inactivated derivatives
KDW03_04650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KDW03_04660	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KDW03_04665	COG1477	protein flavinylation
KDW03_04670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KDW03_04685	COG3118	belongs to the thioredoxin family
KDW03_04695	COG2072	flavoprotein involved in K transport
KDW03_04700	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KDW03_04715	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KDW03_04730	COG0037	tRNA processing
KDW03_04735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KDW03_04765	COG4786	Flagellar basal body rod
KDW03_04770	COG0513	Belongs to the DEAD box helicase family
KDW03_04795	COG2801	Transposase and inactivated derivatives
KDW03_04805	COG1166	arginine decarboxylase activity
KDW03_04820	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KDW03_04850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KDW03_04860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KDW03_04875	COG0124	histidyl-tRNA synthetase
KDW03_04890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KDW03_04895	COG0515	serine threonine protein kinase
KDW03_04895	COG2815	serine threonine protein kinase
KDW03_04900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KDW03_04905	COG0242	peptide deformylase activity
KDW03_04910	COG2866	Carboxypeptidase
KDW03_04920	COG1937	Protein conserved in bacteria
KDW03_04935	COG2217	Heavy metal translocating P-type atpase
KDW03_04950	COG2199	diguanylate cyclase activity
KDW03_04950	COG2200	EAL domain
KDW03_04950	COG3287	FIST C domain
KDW03_04980	COG2183	response to ionizing radiation
KDW03_04985	COG1968	undecaprenyl-diphosphatase activity
KDW03_05000	COG1047	Peptidyl-prolyl cis-trans
KDW03_05010	COG0047	phosphoribosylformylglycinamidine synthase activity
KDW03_05015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KDW03_05020	COG5002	protein histidine kinase activity
KDW03_05025	COG0300	oxidoreductase activity
KDW03_05120	COG3328	transposase activity
KDW03_05130	COG4213	ABC transporter substrate-binding protein
KDW03_05140	COG4214	carbohydrate transport
KDW03_05145	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KDW03_05150	COG2770	Histidine kinase
KDW03_05150	COG2208	phosphoserine phosphatase activity
KDW03_05155	COG1917	Cupin 2, conserved barrel domain protein
KDW03_05160	COG1129	ABC transporter
KDW03_05180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KDW03_05185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KDW03_05210	COG2801	Transposase and inactivated derivatives
KDW03_05220	COG0539	negative regulation of cytoplasmic translation
KDW03_05230	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KDW03_05235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KDW03_05240	COG0084	hydrolase, TatD family'
KDW03_05245	COG0739	heme binding
KDW03_05260	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KDW03_05265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KDW03_05270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KDW03_05275	COG1609	Transcriptional regulator
KDW03_05285	COG0366	Alpha amylase catalytic
KDW03_05285	COG3103	Sh3 type 3 domain protein
KDW03_05290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KDW03_05315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KDW03_05325	COG2226	methyltransferase
KDW03_05340	COG1609	Transcriptional regulator
KDW03_05345	COG2385	sporulation resulting in formation of a cellular spore
KDW03_05355	COG0488	(ABC) transporter
KDW03_05365	COG1269	ATP hydrolysis coupled proton transport
KDW03_05390	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
KDW03_05395	COG0811	peptide transport
KDW03_05400	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KDW03_05405	COG0154	amidase activity
KDW03_05410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KDW03_05450	COG0347	Belongs to the P(II) protein family
KDW03_05455	COG0004	ammonium transporteR
KDW03_05460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KDW03_05485	COG0778	Nitroreductase
KDW03_05520	COG1136	(ABC) transporter
KDW03_05525	COG1012	belongs to the aldehyde dehydrogenase family
KDW03_05545	COG1418	mRNA catabolic process
KDW03_05560	COG1937	Protein conserved in bacteria
KDW03_05575	COG2217	Heavy metal translocating P-type atpase
KDW03_05590	COG3328	transposase activity
KDW03_05630	COG0436	Aminotransferase
KDW03_05635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KDW03_05665	COG0018	arginyl-trna synthetase
KDW03_05680	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KDW03_05685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KDW03_05700	COG2003	Belongs to the UPF0758 family
KDW03_05705	COG1704	LemA family
KDW03_05780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KDW03_05780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KDW03_05790	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KDW03_05795	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KDW03_05800	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KDW03_05810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KDW03_05815	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KDW03_05835	COG0629	single-stranded DNA binding
KDW03_05870	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KDW03_05875	COG0049	tRNA binding
KDW03_05880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KDW03_05885	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KDW03_05890	COG0051	transcription antitermination factor activity, RNA binding
KDW03_05895	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KDW03_05900	COG0088	Forms part of the polypeptide exit tunnel
KDW03_05905	COG0089	rRNA binding
KDW03_05910	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KDW03_05915	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KDW03_05925	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KDW03_05930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KDW03_05935	COG0255	Belongs to the universal ribosomal protein uL29 family
KDW03_05945	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KDW03_05950	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KDW03_05955	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KDW03_05960	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KDW03_05965	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KDW03_05970	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KDW03_05975	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KDW03_05995	COG0563	adenylate kinase activity
KDW03_06000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KDW03_06005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KDW03_06010	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KDW03_06015	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KDW03_06020	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KDW03_06025	COG0202	RNA polymerase activity
KDW03_06075	COG0438	transferase activity, transferring glycosyl groups
KDW03_06080	COG0135	phosphoribosylanthranilate isomerase activity
KDW03_06090	COG1523	belongs to the glycosyl hydrolase 13 family
KDW03_06105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KDW03_06115	COG4608	Belongs to the ABC transporter superfamily
KDW03_06125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KDW03_06130	COG0601	transmembrane transport
KDW03_06135	COG4166	transmembrane transport
KDW03_06140	COG3328	transposase activity
KDW03_06165	COG3328	transposase activity
KDW03_06170	COG1338	Plays a role in the flagellum-specific transport system
KDW03_06180	COG1684	flagellar biosynthetic protein fliR
KDW03_06185	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KDW03_06190	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KDW03_06205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KDW03_06210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KDW03_06215	COG1692	metallophosphoesterase
KDW03_06230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KDW03_06235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KDW03_06250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KDW03_06255	COG2801	Transposase and inactivated derivatives
KDW03_06280	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KDW03_06280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KDW03_06285	COG1872	DUF167
KDW03_06295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KDW03_06300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KDW03_06305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KDW03_06310	COG4956	integral membrane protein (PIN domain superfamily)
KDW03_06315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KDW03_06345	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KDW03_06350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KDW03_06480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KDW03_06485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KDW03_06495	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KDW03_06525	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KDW03_06530	COG1776	CheC inhibitor of MCP methylation
KDW03_06530	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KDW03_06545	COG0180	Tryptophanyl-tRNA synthetase
KDW03_06560	COG0077	Prephenate dehydratase
KDW03_06560	COG1605	Chorismate mutase
KDW03_06565	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KDW03_06570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KDW03_06580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KDW03_06605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KDW03_06615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KDW03_06615	COG1328	CTP reductase activity
KDW03_06640	COG0714	Associated with various cellular activities
KDW03_06645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KDW03_06650	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KDW03_06670	COG0432	Pfam Uncharacterised protein family UPF0047
KDW03_06675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KDW03_06695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KDW03_06705	COG3328	transposase activity
KDW03_06715	COG2373	Large extracellular alpha-helical protein
KDW03_06735	COG3328	transposase activity
KDW03_06775	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KDW03_06780	COG0516	GMP reductase activity
KDW03_06780	COG0517	IMP dehydrogenase activity
KDW03_06790	COG0514	ATP-dependent DNA helicase (RecQ)
KDW03_06800	COG0826	peptidase U32
KDW03_06830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KDW03_06855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KDW03_06860	COG0113	porphobilinogen synthase activity
KDW03_06865	COG1648	precorrin-2 dehydrogenase activity
KDW03_06865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KDW03_06870	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KDW03_06875	COG1648	precorrin-2 dehydrogenase activity
KDW03_06875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KDW03_06890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KDW03_06905	COG0175	sulfate reduction
KDW03_06910	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KDW03_06930	COG2210	Belongs to the sulfur carrier protein TusA family
KDW03_06935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KDW03_06940	COG2873	o-acetylhomoserine
KDW03_06950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KDW03_06980	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KDW03_06990	COG3421	Type III restriction
KDW03_06995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KDW03_07005	COG0438	transferase activity, transferring glycosyl groups
KDW03_07025	COG0564	pseudouridine synthase activity
KDW03_07030	COG0366	Alpha amylase catalytic
KDW03_07035	COG1355	regulation of microtubule-based process
KDW03_07040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KDW03_07050	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KDW03_07055	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KDW03_07070	COG3328	transposase activity
KDW03_07095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KDW03_07100	COG0564	pseudouridine synthase activity
KDW03_07105	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KDW03_07110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KDW03_07140	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KDW03_07145	COG0594	ribonuclease P activity
KDW03_07150	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KDW03_07170	COG1215	transferase activity, transferring glycosyl groups
KDW03_07175	COG0504	CTP synthase activity
KDW03_07180	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KDW03_07185	COG0756	dUTP diphosphatase activity
KDW03_07190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KDW03_07230	COG0698	ribose 5-phosphate isomerase
KDW03_07235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KDW03_07245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KDW03_07275	COG2165	general secretion pathway protein
KDW03_07335	COG0516	GMP reductase activity
KDW03_07335	COG0517	IMP dehydrogenase activity
KDW03_07350	COG4974	Belongs to the 'phage' integrase family
KDW03_07360	COG0632	four-way junction helicase activity
KDW03_07400	COG0544	peptidyl-prolyl cis-trans isomerase activity
KDW03_07415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KDW03_07415	COG1199	ATP-dependent helicase activity
KDW03_07420	COG0215	cysteine-tRNA ligase activity
KDW03_07425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KDW03_07430	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KDW03_07455	COG0658	competence protein
KDW03_07455	COG2333	competence protein COMEC
KDW03_07480	COG0671	phosphoesterase, PA-phosphatase related
KDW03_07490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KDW03_07525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KDW03_07530	COG0667	Aldo Keto reductase
KDW03_07535	COG1283	sodium-dependent phosphate transmembrane transporter activity
KDW03_07540	COG0745	RESPONSE REGULATOR receiver
KDW03_07550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KDW03_07555	COG4139	cobalamin transport
KDW03_07560	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KDW03_07565	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
KDW03_07570	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KDW03_07580	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KDW03_07600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KDW03_07620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KDW03_07645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KDW03_07650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KDW03_07655	COG2770	Histidine kinase
KDW03_07655	COG2208	phosphoserine phosphatase activity
KDW03_07670	COG0840	transmembrane signaling receptor activity
KDW03_07680	COG0432	Pfam Uncharacterised protein family UPF0047
KDW03_07685	COG0348	domain, Protein
KDW03_07690	COG0741	lytic transglycosylase activity
KDW03_07690	COG1388	LysM domain
KDW03_07695	COG0071	Belongs to the small heat shock protein (HSP20) family
KDW03_07700	COG0071	Belongs to the small heat shock protein (HSP20) family
KDW03_07705	COG0071	Belongs to the small heat shock protein (HSP20) family
KDW03_07710	COG1881	PFAM PEBP family protein
KDW03_07720	COG0165	Argininosuccinate lyase
KDW03_07730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KDW03_07735	COG0823	Involved in the tonB-independent uptake of proteins
KDW03_07750	COG0228	four-way junction DNA binding
KDW03_07755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KDW03_07760	COG0336	Belongs to the RNA methyltransferase TrmD family
KDW03_07770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KDW03_07775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KDW03_07780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KDW03_07785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KDW03_07820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KDW03_07830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KDW03_07835	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KDW03_07845	COG1595	DNA-templated transcription, initiation
KDW03_07865	COG2801	Transposase and inactivated derivatives
KDW03_07940	COG2801	Transposase and inactivated derivatives
KDW03_08020	COG0058	SHG alpha-glucan phosphorylase activity
KDW03_08030	COG0297	glycogen (starch) synthase activity
KDW03_08065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KDW03_08075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KDW03_08100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KDW03_08100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KDW03_08105	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KDW03_08115	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KDW03_08125	COG1640	4-alpha-glucanotransferase
KDW03_08140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KDW03_08145	COG0205	6-phosphofructokinase activity
KDW03_08155	COG3437	response regulator, receiver
KDW03_08155	COG0784	Response regulator, receiver
KDW03_08160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KDW03_08160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KDW03_08170	COG1785	Belongs to the alkaline phosphatase family
KDW03_08175	COG0739	heme binding
KDW03_08180	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KDW03_08195	COG0653	protein targeting
KDW03_08200	COG0557	exoribonuclease II activity
KDW03_08215	COG0352	thiamine-phosphate diphosphorylase activity
KDW03_08235	COG2801	Transposase and inactivated derivatives
KDW03_08250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KDW03_08270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KDW03_08280	COG0137	argininosuccinate synthase activity
KDW03_08285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KDW03_08295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KDW03_08305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KDW03_08310	COG2885	chlorophyll binding
KDW03_08320	COG1454	alcohol dehydrogenase
KDW03_08325	COG0668	transmembrane transport
KDW03_08345	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KDW03_08375	COG1366	Belongs to the anti-sigma-factor antagonist family
KDW03_08380	COG1304	FMN binding
KDW03_08385	COG0483	inositol monophosphate 1-phosphatase activity
KDW03_08400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KDW03_08410	COG0740	serine-type endopeptidase activity
KDW03_08415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KDW03_08460	COG2201	protein-glutamate methylesterase activity
KDW03_08465	COG0643	Histidine kinase
KDW03_08465	COG2198	Histidine kinase
KDW03_08470	COG0835	chemotaxis
KDW03_08480	COG2201	protein-glutamate methylesterase activity
KDW03_08485	COG1940	carbohydrate kinase activity
KDW03_08505	COG0788	formyltetrahydrofolate deformylase activity
KDW03_08510	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KDW03_08520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KDW03_08535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KDW03_08540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KDW03_08550	COG0393	Putative heavy-metal-binding
KDW03_08575	COG2801	Transposase and inactivated derivatives
KDW03_08585	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KDW03_08595	COG0484	heat shock protein binding
KDW03_08600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KDW03_08605	COG0107	imidazoleglycerol-phosphate synthase activity
KDW03_08610	COG0546	phosphoglycolate phosphatase activity
KDW03_08615	COG1132	(ABC) transporter
KDW03_08630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KDW03_08635	COG1027	Aspartate ammonia-lyase
KDW03_08650	COG0745	RESPONSE REGULATOR receiver
KDW03_08655	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KDW03_08655	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KDW03_08675	COG2801	Transposase and inactivated derivatives
KDW03_08705	COG3328	transposase activity
KDW03_08725	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KDW03_08730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KDW03_08740	COG2801	Transposase and inactivated derivatives
KDW03_08760	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KDW03_08780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KDW03_08785	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KDW03_08790	COG0357	Ribosomal RNA small subunit methyltransferase G
KDW03_08795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KDW03_08810	COG1116	anion transmembrane transporter activity
KDW03_08815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KDW03_08830	COG3958	Transketolase
KDW03_08835	COG0731	radical SAM domain protein
KDW03_08835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KDW03_08855	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KDW03_08875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KDW03_08880	COG2078	PFAM AMMECR1 domain protein
KDW03_08895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KDW03_08900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KDW03_08910	COG0751	glycine-tRNA ligase activity
KDW03_08915	COG0784	Response regulator, receiver
KDW03_08915	COG3437	response regulator, receiver
KDW03_08920	COG1119	ATPase activity
KDW03_08930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KDW03_08950	COG0366	Alpha amylase catalytic
KDW03_08960	COG1815	bacterial-type flagellum-dependent cell motility
KDW03_08975	COG1766	The M ring may be actively involved in energy transduction
KDW03_08985	COG1317	bacterial-type flagellum organization
KDW03_08990	COG1157	protein secretion by the type III secretion system
KDW03_09000	COG1546	Belongs to the CinA family
KDW03_09000	COG1058	Belongs to the CinA family
KDW03_09040	COG2033	superoxide reductase activity
KDW03_09055	COG1528	Iron-storage protein
KDW03_09080	COG1396	sequence-specific DNA binding
KDW03_09085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KDW03_09100	COG0704	Plays a role in the regulation of phosphate uptake
KDW03_09105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KDW03_09110	COG0581	inorganic phosphate transmembrane transporter activity
KDW03_09120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KDW03_09130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KDW03_09150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KDW03_09185	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KDW03_09185	COG2199	diguanylate cyclase activity
KDW03_09190	COG1045	serine acetyltransferase
KDW03_09195	COG0564	pseudouridine synthase activity
KDW03_09200	COG0501	Belongs to the peptidase M48B family
KDW03_09230	COG2723	6-phospho-beta-galactosidase activity
KDW03_09265	COG0493	'glutamate synthase
KDW03_09280	COG3328	transposase activity
KDW03_09325	COG2801	Transposase and inactivated derivatives
KDW03_09335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KDW03_09340	COG2890	protein-(glutamine-N5) methyltransferase activity
KDW03_09350	COG2801	Transposase and inactivated derivatives
KDW03_09355	COG3328	transposase activity
KDW03_09400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KDW03_09405	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KDW03_09410	COG0720	synthase
KDW03_09420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KDW03_09430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KDW03_09435	COG1216	Glycosyl transferase, family 2
KDW03_09435	COG1442	glycosyl transferase family 8
KDW03_09440	COG0297	glycogen (starch) synthase activity
KDW03_09445	COG1713	HD superfamily hydrolase involved in NAD metabolism
KDW03_09470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KDW03_09495	COG1570	exodeoxyribonuclease VII activity
KDW03_09515	COG0577	efflux transmembrane transporter activity
KDW03_09515	COG1136	(ABC) transporter
KDW03_09520	COG0577	efflux transmembrane transporter activity
KDW03_09520	COG1136	(ABC) transporter
KDW03_09550	COG1141	Ferredoxin
KDW03_09580	COG1136	(ABC) transporter
KDW03_09600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KDW03_09620	COG1706	bacterial-type flagellum-dependent cell motility
KDW03_09635	COG3328	transposase activity
KDW03_09645	COG2801	Transposase and inactivated derivatives
KDW03_09665	COG2801	Transposase and inactivated derivatives
KDW03_09690	COG0167	dihydroorotate dehydrogenase activity
KDW03_09695	COG2199	diguanylate cyclase activity
KDW03_09705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KDW03_09705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KDW03_09710	COG2860	membrane
KDW03_09745	COG1971	Probably functions as a manganese efflux pump
KDW03_09750	COG0148	phosphopyruvate hydratase activity
KDW03_09755	COG2211	Major facilitator Superfamily
KDW03_09765	COG3328	transposase activity
KDW03_09780	COG2089	acid synthase
KDW03_09815	COG2801	Transposase and inactivated derivatives
KDW03_09860	COG1104	cysteine desulfurase activity
KDW03_09870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KDW03_09875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KDW03_09890	COG0714	Associated with various cellular activities
KDW03_09900	COG1329	Transcriptional regulator
KDW03_09915	COG0105	UTP biosynthetic process
KDW03_09920	COG0693	protein deglycase activity
KDW03_09930	COG0495	leucyl-tRNA aminoacylation
KDW03_09935	COG0187	DNA topoisomerase II activity
KDW03_09945	COG1469	GTP cyclohydrolase I activity
KDW03_09955	COG0802	atpase or kinase
KDW03_09970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KDW03_09990	COG1639	'signal transduction protein
KDW03_09995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KDW03_10005	COG1774	PSP1 C-terminal conserved region
KDW03_10010	COG1254	Belongs to the acylphosphatase family
KDW03_10025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KDW03_10040	COG2409	Drug exporters of the RND superfamily
KDW03_10040	COG1033	growth of symbiont in host cell
KDW03_10060	COG2801	Transposase and inactivated derivatives
KDW03_10070	COG0179	Fumarylacetoacetate (FAA) hydrolase
KDW03_10075	COG3706	GGDEF domain
KDW03_10085	COG1722	exodeoxyribonuclease VII activity
KDW03_10100	COG2020	methyltransferase activity
KDW03_10105	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KDW03_10110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KDW03_10115	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KDW03_10120	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KDW03_10125	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KDW03_10150	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KDW03_10165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KDW03_10180	COG0358	DNA primase activity
KDW03_10185	COG1496	oxidoreductase activity
KDW03_10210	COG0659	secondary active sulfate transmembrane transporter activity
KDW03_10230	COG4536	flavin adenine dinucleotide binding
KDW03_10235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KDW03_10255	COG0776	regulation of translation
KDW03_10265	COG1193	negative regulation of DNA recombination
KDW03_10270	COG0438	transferase activity, transferring glycosyl groups
KDW03_10290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KDW03_10300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KDW03_10300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KDW03_10310	COG2195	Cleaves the N-terminal amino acid of tripeptides
KDW03_10320	COG3328	transposase activity
KDW03_10330	COG4191	Histidine kinase
KDW03_10335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KDW03_10340	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KDW03_10355	COG0617	tRNA 3'-terminal CCA addition
KDW03_10365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KDW03_10375	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KDW03_10400	COG1543	Belongs to the glycosyl hydrolase 57 family
KDW03_10405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KDW03_10410	COG0012	GTP binding
KDW03_10420	COG0460	homoserine dehydrogenase
KDW03_10435	COG4591	ABC-type transport system involved in lipoprotein release permease component
KDW03_10445	COG2177	Part of the ABC transporter FtsEX involved in
KDW03_10450	COG1136	(ABC) transporter
KDW03_10450	COG0577	efflux transmembrane transporter activity
KDW03_10455	COG2801	Transposase and inactivated derivatives
KDW03_10460	COG0322	excinuclease ABC activity
KDW03_10625	COG0602	queuosine metabolic process
KDW03_10640	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KDW03_10660	COG3328	transposase activity
KDW03_10680	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KDW03_10685	COG0793	Belongs to the peptidase S41A family
KDW03_10685	COG3409	Peptidoglycan-binding domain 1 protein
KDW03_10690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KDW03_10695	COG1137	ATPase activity
KDW03_10700	COG0484	heat shock protein binding
KDW03_10705	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KDW03_10745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KDW03_10750	COG2801	Transposase and inactivated derivatives
KDW03_10755	COG0505	Belongs to the CarA family
KDW03_10765	COG0321	lipoyl(octanoyl) transferase activity
KDW03_10765	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KDW03_10805	COG1874	Beta-galactosidase
KDW03_10805	COG0366	Alpha amylase catalytic
KDW03_10820	COG1874	Beta-galactosidase
KDW03_10820	COG0366	Alpha amylase catalytic
KDW03_10825	COG1620	l-lactate permease
KDW03_10830	COG4638	Rieske (2fe-2S)
KDW03_10840	COG5002	protein histidine kinase activity
KDW03_10845	COG0037	tRNA processing
KDW03_10855	COG0326	Molecular chaperone. Has ATPase activity
KDW03_10860	COG0233	cytoplasmic translational termination
KDW03_10865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KDW03_10870	COG4589	Belongs to the CDS family
KDW03_10875	COG0101	tRNA pseudouridine synthase activity
KDW03_10890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KDW03_10920	COG1639	'signal transduction protein
KDW03_10925	COG2801	Transposase and inactivated derivatives
KDW03_10930	COG0131	Imidazoleglycerol-phosphate dehydratase
KDW03_10935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KDW03_10945	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KDW03_10955	COG2382	esterase
KDW03_10980	COG0138	bifunctional purine biosynthesis protein purh
KDW03_10995	COG3833	ABC-type maltose transport systems, permease component
KDW03_11000	COG1175	transmembrane transport
KDW03_11015	COG0151	Belongs to the GarS family
KDW03_11020	COG1160	GTP binding
KDW03_11050	COG0543	2 iron, 2 sulfur cluster binding
KDW03_11075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KDW03_11080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KDW03_11105	COG3706	GGDEF domain
KDW03_11105	COG4251	negative regulation of phosphorylation
KDW03_11105	COG5001	Diguanylate cyclase
KDW03_11105	COG2203	Gaf domain
KDW03_11115	COG1525	nuclease
KDW03_11120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KDW03_11125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KDW03_11160	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KDW03_11175	COG2192	nodulation
KDW03_11210	COG0556	nucleotide-excision repair
KDW03_11215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KDW03_11230	COG0439	Biotin carboxylase
KDW03_11240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KDW03_11245	COG0006	proline dipeptidase activity
KDW03_11255	COG0191	fructose-bisphosphate aldolase activity
KDW03_11260	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KDW03_11265	COG0159	tryptophan synthase activity
KDW03_11290	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KDW03_11295	COG3706	GGDEF domain
KDW03_11295	COG4251	negative regulation of phosphorylation
KDW03_11295	COG5001	Diguanylate cyclase
KDW03_11295	COG2203	Gaf domain
KDW03_11300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KDW03_11310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KDW03_11315	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KDW03_11330	COG0205	6-phosphofructokinase activity
KDW03_11335	COG0825	malonyl-CoA metabolic process
KDW03_11340	COG2801	Transposase and inactivated derivatives
KDW03_11365	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
KDW03_11370	COG1811	Na channel or pump
KDW03_11375	COG0445	tRNA wobble uridine modification
KDW03_11380	COG3706	GGDEF domain
KDW03_11385	COG0366	Alpha amylase catalytic
KDW03_11390	COG2801	Transposase and inactivated derivatives
KDW03_11425	COG0343	queuine tRNA-ribosyltransferase activity
KDW03_11440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KDW03_11445	COG1141	Ferredoxin
KDW03_11455	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KDW03_11465	COG1639	'signal transduction protein
KDW03_11485	COG0442	prolyl-tRNA aminoacylation
KDW03_11490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KDW03_11550	COG0778	Nitroreductase
KDW03_11560	COG0371	Dehydrogenase
KDW03_11585	COG2095	MarC family integral membrane protein
KDW03_11605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KDW03_11610	COG0134	indole-3-glycerol-phosphate synthase activity
KDW03_11615	COG0512	Glutamine amidotransferase of anthranilate synthase
KDW03_11615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KDW03_11620	COG1690	Belongs to the RtcB family
KDW03_11625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KDW03_11630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KDW03_11630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KDW03_11635	COG1269	ATP hydrolysis coupled proton transport
KDW03_11655	COG1394	ATPase activity, coupled to movement of substances
KDW03_11660	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
KDW03_11665	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
KDW03_11760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KDW03_11785	COG1136	(ABC) transporter
KDW03_11800	COG0643	Histidine kinase
KDW03_11800	COG2198	Histidine kinase
KDW03_11810	COG0835	chemotaxis
KDW03_11815	COG0745	RESPONSE REGULATOR receiver
KDW03_11825	COG2201	protein-glutamate methylesterase activity
KDW03_11830	COG0840	transmembrane signaling receptor activity
KDW03_11845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KDW03_11850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KDW03_11855	COG1862	Preprotein translocase
KDW03_11880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KDW03_11885	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KDW03_11915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KDW03_11920	COG0024	Methionine aminopeptidase
KDW03_11935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KDW03_11940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KDW03_11955	COG1040	competence protein
KDW03_11960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KDW03_11965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KDW03_11970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KDW03_11980	COG0436	Aminotransferase
KDW03_11985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KDW03_11990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KDW03_12000	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KDW03_12005	COG0546	phosphoglycolate phosphatase activity
KDW03_12010	COG0799	negative regulation of ribosome biogenesis
KDW03_12030	COG1185	polyribonucleotide nucleotidyltransferase activity
KDW03_12035	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KDW03_12040	COG0196	riboflavin kinase activity
KDW03_12045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KDW03_12050	COG0728	peptidoglycan biosynthetic process
KDW03_12060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KDW03_12065	COG0318	PFAM AMP-dependent synthetase and ligase
KDW03_12080	COG0052	Belongs to the universal ribosomal protein uS2 family
KDW03_12085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KDW03_12090	COG0528	UMP kinase activity
KDW03_12095	COG0742	ribosomal rna small subunit methyltransferase
KDW03_12105	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
KDW03_12110	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KDW03_12115	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KDW03_12120	COG0287	Prephenate dehydrogenase
KDW03_12125	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KDW03_12145	COG0037	tRNA processing
KDW03_12150	COG0193	aminoacyl-tRNA hydrolase activity
KDW03_12155	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KDW03_12160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KDW03_12170	COG2088	sporulation resulting in formation of a cellular spore
KDW03_12185	COG1136	(ABC) transporter
KDW03_12190	COG4591	ABC-type transport system involved in lipoprotein release permease component