locus-tag	class	description
D3A95_00005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D3A95_00005	COG0758	DNA mediated transformation
D3A95_00030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D3A95_00035	COG1132	(ABC) transporter
D3A95_00040	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D3A95_00045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D3A95_00050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D3A95_00060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3A95_00060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D3A95_00070	COG0625	glutathione transferase activity
D3A95_00075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D3A95_00085	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3A95_00085	COG0022	dehydrogenase e1 component
D3A95_00090	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3A95_00095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3A95_00130	COG2205	protein histidine kinase activity
D3A95_00145	COG0735	belongs to the Fur family
D3A95_00155	COG0285	dihydrofolate synthase activity
D3A95_00165	COG0004	ammonium transporteR
D3A95_00170	COG0395	ABC-type sugar transport system, permease component
D3A95_00175	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D3A95_00180	COG0459	protein refolding
D3A95_00185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D3A95_00190	COG0788	formyltetrahydrofolate deformylase activity
D3A95_00200	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D3A95_00210	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
D3A95_00215	COG1012	belongs to the aldehyde dehydrogenase family
D3A95_00220	COG4178	(ABC) transporter
D3A95_00235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D3A95_00240	COG1454	alcohol dehydrogenase
D3A95_00240	COG1012	belongs to the aldehyde dehydrogenase family
D3A95_00245	COG0095	Lipoate-protein ligase
D3A95_00260	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D3A95_00270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D3A95_00270	COG0140	phosphoribosyl-ATP diphosphatase activity
D3A95_00290	COG0842	Transport permease protein
D3A95_00290	COG1131	(ABC) transporter
D3A95_00290	COG1716	ATPase activity
D3A95_00295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3A95_00295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3A95_00300	COG0612	Peptidase, M16
D3A95_00305	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D3A95_00335	COG0156	8-amino-7-oxononanoate synthase activity
D3A95_00340	COG0745	RESPONSE REGULATOR receiver
D3A95_00345	COG0842	Transport permease protein
D3A95_00345	COG1716	ATPase activity
D3A95_00345	COG1131	(ABC) transporter
D3A95_00350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3A95_00355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3A95_00365	COG1357	PFAM Pentapeptide repeats (8 copies)
D3A95_00365	COG0515	serine threonine protein kinase
D3A95_00385	COG0704	Plays a role in the regulation of phosphate uptake
D3A95_00440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D3A95_00475	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D3A95_00480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D3A95_00485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3A95_00495	COG1472	Belongs to the glycosyl hydrolase 3 family
D3A95_00500	COG2046	Belongs to the sulfate adenylyltransferase family
D3A95_00515	COG0438	transferase activity, transferring glycosyl groups
D3A95_00520	COG0745	RESPONSE REGULATOR receiver
D3A95_00560	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D3A95_00570	COG1528	Iron-storage protein
D3A95_00575	COG0742	ribosomal rna small subunit methyltransferase
D3A95_00580	COG0667	Aldo Keto reductase
D3A95_00590	COG2099	Precorrin-6x reductase
D3A95_00595	COG0129	dihydroxy-acid dehydratase activity
D3A95_00615	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D3A95_00635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D3A95_00655	COG0612	Peptidase, M16
D3A95_00660	COG1716	ATPase activity
D3A95_00660	COG5001	Diguanylate cyclase
D3A95_00665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D3A95_00680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D3A95_00740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D3A95_00745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D3A95_00750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3A95_00760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D3A95_00795	COG4991	sh3 domain protein
D3A95_00795	COG3064	Membrane
D3A95_00795	COG0515	serine threonine protein kinase
D3A95_00840	COG0426	domain, Protein
D3A95_00840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3A95_00845	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D3A95_00885	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D3A95_00900	COG0363	glucosamine-6-phosphate deaminase activity
D3A95_00925	COG0740	serine-type endopeptidase activity
D3A95_00930	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
D3A95_00935	COG0765	amino acid transport
D3A95_00945	COG0484	heat shock protein binding
D3A95_00950	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D3A95_00955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D3A95_00960	COG0434	BtpA family
D3A95_00965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D3A95_00980	COG0217	transcriptional regulatory protein
D3A95_00985	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D3A95_00985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3A95_00995	COG4948	Mandelate Racemase Muconate Lactonizing
D3A95_01005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D3A95_01015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3A95_01015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D3A95_01020	COG0457	Tetratricopeptide repeat
D3A95_01020	COG0463	Glycosyl transferase, family 2
D3A95_01025	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D3A95_01030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D3A95_01080	COG2119	membrane
D3A95_01095	COG2385	sporulation resulting in formation of a cellular spore
D3A95_01135	COG2247	cell wall binding repeat
D3A95_01135	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3A95_01190	COG0339	signal peptide processing
D3A95_01195	COG0741	lytic transglycosylase activity
D3A95_01195	COG0739	heme binding
D3A95_01195	COG1196	nuclear chromosome segregation
D3A95_01200	COG0768	penicillin binding
D3A95_01210	COG0107	imidazoleglycerol-phosphate synthase activity
D3A95_01215	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
D3A95_01220	COG0084	hydrolase, TatD family'
D3A95_01225	COG0268	Binds directly to 16S ribosomal RNA
D3A95_01230	COG1691	(AIR) carboxylase
D3A95_01245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3A95_01275	COG1131	(ABC) transporter
D3A95_01285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D3A95_01285	COG0512	Glutamine amidotransferase of anthranilate synthase
D3A95_01310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3A95_01315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3A95_01335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3A95_01345	COG0515	serine threonine protein kinase
D3A95_01345	COG3266	domain, Protein
D3A95_01375	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D3A95_01380	COG0765	amino acid transport
D3A95_01385	COG0450	alkyl hydroperoxide reductase
D3A95_01400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3A95_01415	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D3A95_01430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D3A95_01440	COG0724	RNA recognition motif
D3A95_01470	COG1063	alcohol dehydrogenase
D3A95_01485	COG1494	fructose-1,6-bisphosphatase
D3A95_01490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D3A95_01500	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D3A95_01525	COG3631	Ketosteroid isomerase-related protein
D3A95_01540	COG2062	phosphohistidine phosphatase, SixA
D3A95_01555	COG0745	RESPONSE REGULATOR receiver
D3A95_01570	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D3A95_01595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3A95_01600	COG0671	phosphoesterase, PA-phosphatase related
D3A95_01610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D3A95_01625	COG2082	Precorrin-8x methylmutase
D3A95_01645	COG1959	2 iron, 2 sulfur cluster binding
D3A95_01655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D3A95_01660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D3A95_01680	COG3842	ATPase activity
D3A95_01690	COG3411	Ferredoxin
D3A95_01705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3A95_01720	COG1049	propionate catabolic process, 2-methylcitrate cycle
D3A95_01725	COG1192	Involved in chromosome partitioning
D3A95_01730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D3A95_01755	COG0408	coproporphyrinogen oxidase activity
D3A95_01760	COG1333	cytochrome c biogenesis protein
D3A95_01770	COG2217	Heavy metal translocating P-type atpase
D3A95_01820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3A95_01825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3A95_01830	COG0713	ATP synthesis coupled electron transport
D3A95_01835	COG0839	Belongs to the complex I subunit 6 family
D3A95_01840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_01845	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
D3A95_01850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3A95_01855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3A95_01860	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3A95_01865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D3A95_01875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3A95_01875	COG0072	phenylalanine-tRNA ligase activity
D3A95_01880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D3A95_01890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D3A95_01895	COG0148	phosphopyruvate hydratase activity
D3A95_01900	COG2217	Heavy metal translocating P-type atpase
D3A95_01905	COG1187	pseudouridine synthase activity
D3A95_01910	COG1132	(ABC) transporter
D3A95_01925	COG0557	exoribonuclease II activity
D3A95_01940	COG0519	Catalyzes the synthesis of GMP from XMP
D3A95_01940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D3A95_01955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D3A95_01960	COG1372	Participates in initiation and elongation during chromosome replication
D3A95_01960	COG0187	DNA topoisomerase II activity
D3A95_01970	COG1187	pseudouridine synthase activity
D3A95_01975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3A95_01985	COG0577	efflux transmembrane transporter activity
D3A95_01985	COG1136	(ABC) transporter
D3A95_01990	COG0085	RNA polymerase activity
D3A95_01995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D3A95_02000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D3A95_02005	COG0501	Belongs to the peptidase M48B family
D3A95_02035	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D3A95_02080	COG0515	serine threonine protein kinase
D3A95_02085	COG1716	ATPase activity
D3A95_02090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3A95_02095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3A95_02120	COG0523	cobalamin synthesis protein
D3A95_02125	COG3659	wide pore channel activity
D3A95_02130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3A95_02130	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D3A95_02140	COG1606	tRNA processing
D3A95_02150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D3A95_02160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D3A95_02170	COG0601	transmembrane transport
D3A95_02185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D3A95_02200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D3A95_02210	COG0842	Transport permease protein
D3A95_02210	COG1131	(ABC) transporter
D3A95_02210	COG1716	ATPase activity
D3A95_02230	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D3A95_02240	COG0745	RESPONSE REGULATOR receiver
D3A95_02245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3A95_02255	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D3A95_02265	COG2081	HI0933 family
D3A95_02270	COG0668	transmembrane transport
D3A95_02280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D3A95_02305	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
D3A95_02310	COG1252	NADH dehydrogenase
D3A95_02315	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
D3A95_02330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D3A95_02350	COG0515	serine threonine protein kinase
D3A95_02350	COG1357	PFAM Pentapeptide repeats (8 copies)
D3A95_02360	COG0515	serine threonine protein kinase
D3A95_02375	COG0287	Prephenate dehydrogenase
D3A95_02380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3A95_02395	COG1122	ATPase activity
D3A95_02405	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
D3A95_02410	COG0310	cobalt ion transport
D3A95_02415	COG1799	cell septum assembly
D3A95_02425	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D3A95_02440	COG1473	amidohydrolase
D3A95_02455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D3A95_02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D3A95_02475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3A95_02485	COG0384	phenazine biosynthesis protein PhzF
D3A95_02490	COG0105	UTP biosynthetic process
D3A95_02495	COG0861	Integral membrane protein TerC family
D3A95_02510	COG1122	ATPase activity
D3A95_02515	COG1429	ligase activity, forming nitrogen-metal bonds
D3A95_02525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D3A95_02530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D3A95_02535	COG4208	sulfate ABC transporter
D3A95_02540	COG0460	homoserine dehydrogenase
D3A95_02550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D3A95_02555	COG0484	heat shock protein binding
D3A95_02560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3A95_02570	COG1842	Phage shock protein A
D3A95_02575	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D3A95_02580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3A95_02595	COG0446	pyridine nucleotide-disulphide oxidoreductase
D3A95_02600	COG0629	single-stranded DNA binding
D3A95_02615	COG4636	protein conserved in cyanobacteria
D3A95_02630	COG0730	response to heat
D3A95_02635	COG0492	ferredoxin-NADP+ reductase activity
D3A95_02650	COG1196	nuclear chromosome segregation
D3A95_02660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D3A95_02665	COG0800	Aldolase
D3A95_02690	COG2045	Belongs to the ComB family
D3A95_02695	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D3A95_02700	COG0598	Magnesium transport protein CorA
D3A95_02715	COG0857	belongs to the CobB CobQ family
D3A95_02745	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D3A95_02755	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
D3A95_02760	COG2894	cell division
D3A95_02765	COG0850	regulation of cytokinetic process
D3A95_02775	COG0515	serine threonine protein kinase
D3A95_02845	COG0180	Tryptophanyl-tRNA synthetase
D3A95_02855	COG1872	DUF167
D3A95_02890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D3A95_02900	COG0004	ammonium transporteR
D3A95_02905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D3A95_02915	COG1234	tRNA 3'-trailer cleavage
D3A95_02945	COG0420	3'-5' exonuclease activity
D3A95_02950	COG0033	Phosphoglucomutase
D3A95_02960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3A95_02965	COG0750	zinc metalloprotease
D3A95_02970	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D3A95_02985	COG0181	hydroxymethylbilane synthase activity
D3A95_03005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3A95_03040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3A95_03045	COG0483	inositol monophosphate 1-phosphatase activity
D3A95_03055	COG5002	protein histidine kinase activity
D3A95_03060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D3A95_03075	COG0247	lactate metabolic process
D3A95_03080	COG0277	FAD linked oxidase domain protein
D3A95_03095	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D3A95_03125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3A95_03130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3A95_03150	COG0242	peptide deformylase activity
D3A95_03160	COG0509	glycine decarboxylation via glycine cleavage system
D3A95_03165	COG0559	Belongs to the binding-protein-dependent transport system permease family
D3A95_03170	COG0248	Ppx GppA phosphatase
D3A95_03180	COG0454	-acetyltransferase
D3A95_03185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3A95_03190	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D3A95_03200	COG0307	riboflavin synthase, alpha
D3A95_03205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D3A95_03210	COG0052	Belongs to the universal ribosomal protein uS2 family
D3A95_03215	COG1192	Involved in chromosome partitioning
D3A95_03225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D3A95_03245	COG1842	Phage shock protein A
D3A95_03250	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D3A95_03260	COG4447	cellulose binding
D3A95_03265	COG1773	rubredoxin
D3A95_03270	COG1489	DNA binding
D3A95_03290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D3A95_03305	COG0357	Ribosomal RNA small subunit methyltransferase G
D3A95_03315	COG3659	wide pore channel activity
D3A95_03320	COG2003	Belongs to the UPF0758 family
D3A95_03325	COG2326	polyphosphate kinase activity
D3A95_03335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D3A95_03345	COG1178	ABC-type Fe3 transport system permease component
D3A95_03350	COG0157	Belongs to the NadC ModD family
D3A95_03355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D3A95_03365	COG1492	cobalamin metabolic process
D3A95_03380	COG0588	phosphoglycerate mutase activity
D3A95_03385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D3A95_03395	COG5002	protein histidine kinase activity
D3A95_03400	COG0745	RESPONSE REGULATOR receiver
D3A95_03405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D3A95_03420	COG0799	negative regulation of ribosome biogenesis
D3A95_03425	COG0318	PFAM AMP-dependent synthetase and ligase
D3A95_03430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D3A95_03435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3A95_03445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3A95_03450	COG1799	cell septum assembly
D3A95_03455	COG5002	protein histidine kinase activity
D3A95_03460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3A95_03475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3A95_03480	COG3706	GGDEF domain
D3A95_03495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D3A95_03500	COG0583	DNA-binding transcription factor activity
D3A95_03505	COG0515	serine threonine protein kinase
D3A95_03505	COG1357	PFAM Pentapeptide repeats (8 copies)
D3A95_03515	COG0504	CTP synthase activity
D3A95_03530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3A95_03535	COG0697	spore germination
D3A95_03550	COG0442	prolyl-tRNA aminoacylation
D3A95_03565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D3A95_03575	COG0058	SHG alpha-glucan phosphorylase activity
D3A95_03580	COG2223	nitrite transmembrane transporter activity
D3A95_03585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D3A95_03600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3A95_03615	COG0484	heat shock protein binding
D3A95_03620	COG0443	Heat shock 70 kDa protein
D3A95_03630	COG1666	GTP binding
D3A95_03665	COG0514	ATP-dependent DNA helicase (RecQ)
D3A95_03680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3A95_03705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D3A95_03710	COG3956	TIGRFAM MazG family protein
D3A95_03715	COG0747	negative chemotaxis
D3A95_03725	COG3118	belongs to the thioredoxin family
D3A95_03740	COG0668	transmembrane transport
D3A95_03745	COG0678	peroxiredoxin activity
D3A95_03745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D3A95_03750	COG2217	Heavy metal translocating P-type atpase
D3A95_03760	COG1899	peptidyl-lysine modification to peptidyl-hypusine
D3A95_03765	COG1121	(ABC) transporter
D3A95_03775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D3A95_03785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D3A95_03790	COG0717	Belongs to the dCTP deaminase family
D3A95_03800	COG0018	arginyl-trna synthetase
D3A95_03820	COG3264	Mechanosensitive ion channel
D3A95_03820	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D3A95_03830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3A95_03835	COG0321	lipoyl(octanoyl) transferase activity
D3A95_03840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3A95_03865	COG0772	Belongs to the SEDS family
D3A95_03870	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D3A95_03895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3A95_03900	COG0416	fatty acid biosynthetic process
D3A95_03905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3A95_03930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D3A95_03935	COG1045	serine acetyltransferase
D3A95_03965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D3A95_03970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3A95_03985	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
D3A95_04010	COG0316	Belongs to the HesB IscA family
D3A95_04015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3A95_04020	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3A95_04040	COG0071	Belongs to the small heat shock protein (HSP20) family
D3A95_04050	COG5002	protein histidine kinase activity
D3A95_04050	COG0784	Response regulator, receiver
D3A95_04050	COG2205	protein histidine kinase activity
D3A95_04060	COG1160	GTP binding
D3A95_04075	COG0440	acetolactate synthase activity
D3A95_04085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D3A95_04100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3A95_04110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3A95_04125	COG1116	anion transmembrane transporter activity
D3A95_04155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D3A95_04160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3A95_04165	COG1836	PFAM Integral membrane protein DUF92
D3A95_04170	COG0463	Glycosyl transferase, family 2
D3A95_04175	COG3385	transposase activity
D3A95_04190	COG1216	Glycosyl transferase, family 2
D3A95_04200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3A95_04205	COG1882	Formate acetyltransferase
D3A95_04220	COG1162	GTPase activity
D3A95_04235	COG1253	flavin adenine dinucleotide binding
D3A95_04255	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D3A95_04260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D3A95_04265	COG0831	urea catabolic process
D3A95_04270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D3A95_04275	COG2048	Heterodisulfide reductase, subunit B
D3A95_04280	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D3A95_04295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3A95_04300	COG1063	alcohol dehydrogenase
D3A95_04305	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D3A95_04320	COG0149	triose-phosphate isomerase activity
D3A95_04330	COG1192	Involved in chromosome partitioning
D3A95_04335	COG1132	(ABC) transporter
D3A95_04380	COG0805	protein transport
D3A95_04385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D3A95_04390	COG1091	dTDP-4-dehydrorhamnose reductase activity
D3A95_04395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D3A95_04415	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D3A95_04420	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
D3A95_04425	COG4451	ribulose bisphosphate carboxylase, small
D3A95_04425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3A95_04435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3A95_04455	COG1077	Cell shape determining protein MreB Mrl
D3A95_04470	COG0741	lytic transglycosylase activity
D3A95_04480	COG1028	Short-chain dehydrogenase reductase Sdr
D3A95_04485	COG0436	Aminotransferase
D3A95_04490	COG0552	protein localization to endoplasmic reticulum
D3A95_04495	COG1218	3'(2'),5'-bisphosphate nucleotidase
D3A95_04505	COG5002	protein histidine kinase activity
D3A95_04510	COG5001	Diguanylate cyclase
D3A95_04510	COG3706	GGDEF domain
D3A95_04510	COG4251	negative regulation of phosphorylation
D3A95_04510	COG2203	Gaf domain
D3A95_04520	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D3A95_04540	COG0596	Alpha beta hydrolase
D3A95_04555	COG1555	photosystem II stabilization
D3A95_04555	COG1234	tRNA 3'-trailer cleavage
D3A95_04565	COG1104	cysteine desulfurase activity
D3A95_04590	COG2239	Acts as a magnesium transporter
D3A95_04595	COG1285	pathogenesis
D3A95_04600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D3A95_04610	COG2189	Belongs to the N(4) N(6)-methyltransferase family
D3A95_04615	COG0189	ligase activity
D3A95_04620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D3A95_04630	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_04635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3A95_04660	COG2205	protein histidine kinase activity
D3A95_04665	COG0237	dephospho-CoA kinase activity
D3A95_04680	COG0602	queuosine metabolic process
D3A95_04695	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D3A95_04700	COG1840	ABC-type Fe3 transport system, periplasmic component
D3A95_04715	COG0469	pyruvate kinase activity
D3A95_04725	COG0470	DNA polymerase III
D3A95_04730	COG0617	tRNA 3'-terminal CCA addition
D3A95_04730	COG0517	IMP dehydrogenase activity
D3A95_04730	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D3A95_04745	COG1181	Belongs to the D-alanine--D-alanine ligase family
D3A95_04755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D3A95_04770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3A95_04775	COG0312	modulator of DNA gyrase
D3A95_04780	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D3A95_04785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D3A95_04795	COG0632	four-way junction helicase activity
D3A95_04815	COG0445	tRNA wobble uridine modification
D3A95_04820	COG0829	nickel cation binding
D3A95_04830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3A95_04830	COG0475	glutathione-regulated potassium exporter activity
D3A95_04835	COG3409	Peptidoglycan-binding domain 1 protein
D3A95_04835	COG3429	Glucose-6-phosphate dehydrogenase subunit
D3A95_04840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D3A95_04845	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D3A95_04890	COG4251	negative regulation of phosphorylation
D3A95_04910	COG1132	(ABC) transporter
D3A95_04925	COG0693	protein deglycase activity
D3A95_04935	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D3A95_04950	COG1086	Polysaccharide biosynthesis protein
D3A95_04965	COG0297	glycogen (starch) synthase activity
D3A95_04970	COG0123	including yeast histone deacetylase and acetoin utilization protein
D3A95_04980	COG1083	cytidylyl-transferase
D3A95_04985	COG3980	spore coat polysaccharide biosynthesis protein
D3A95_04995	COG1598	PFAM Uncharacterised protein family UPF0150
D3A95_05010	COG2089	acid synthase
D3A95_05025	COG0643	Histidine kinase
D3A95_05025	COG0784	Response regulator, receiver
D3A95_05025	COG2198	Histidine kinase
D3A95_05030	COG2203	Gaf domain
D3A95_05030	COG0840	transmembrane signaling receptor activity
D3A95_05045	COG0784	Response regulator, receiver
D3A95_05055	COG3659	wide pore channel activity
D3A95_05070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D3A95_05075	COG1028	Short-chain dehydrogenase reductase Sdr
D3A95_05080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3A95_05085	COG1132	(ABC) transporter
D3A95_05090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D3A95_05095	COG0167	dihydroorotate dehydrogenase activity
D3A95_05105	COG1122	ATPase activity
D3A95_05110	COG0438	transferase activity, transferring glycosyl groups
D3A95_05130	COG0574	Belongs to the PEP-utilizing enzyme family
D3A95_05130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3A95_05135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3A95_05145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D3A95_05150	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3A95_05155	COG4243	Vitamin k epoxide reductase
D3A95_05160	COG0745	RESPONSE REGULATOR receiver
D3A95_05165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D3A95_05175	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D3A95_05200	COG1530	ribonuclease E activity
D3A95_05205	COG2066	Belongs to the glutaminase family
D3A95_05215	COG0706	membrane insertase activity
D3A95_05220	COG0594	ribonuclease P activity
D3A95_05225	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D3A95_05230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D3A95_05235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D3A95_05260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D3A95_05265	COG0701	Predicted permease
D3A95_05270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D3A95_05275	COG0783	Belongs to the Dps family
D3A95_05285	COG2133	pyrroloquinoline quinone binding
D3A95_05295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3A95_05305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3A95_05310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3A95_05320	COG0581	inorganic phosphate transmembrane transporter activity
D3A95_05325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3A95_05330	COG0154	amidase activity
D3A95_05340	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D3A95_05360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3A95_05380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_05395	COG1215	transferase activity, transferring glycosyl groups
D3A95_05405	COG0640	Transcriptional regulator
D3A95_05425	COG0840	transmembrane signaling receptor activity
D3A95_05425	COG2203	Gaf domain
D3A95_05470	COG0559	Belongs to the binding-protein-dependent transport system permease family
D3A95_05480	COG0537	adenosine 5'-monophosphoramidase activity
D3A95_05485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D3A95_05500	COG3706	GGDEF domain
D3A95_05510	COG0165	Argininosuccinate lyase
D3A95_05515	COG5398	heme oxygenase
D3A95_05535	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D3A95_05550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3A95_05585	COG4581	dead DEAH box helicase
D3A95_05590	COG2198	Histidine kinase
D3A95_05590	COG0643	Histidine kinase
D3A95_05590	COG0784	Response regulator, receiver
D3A95_05590	COG2198	Histidine kinase
D3A95_05590	COG0643	Histidine kinase
D3A95_05590	COG0784	Response regulator, receiver
D3A95_05595	COG0840	transmembrane signaling receptor activity
D3A95_05620	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D3A95_05635	COG0429	hydrolase of the alpha beta-hydrolase fold
D3A95_05645	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3A95_05655	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
D3A95_05670	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D3A95_05675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D3A95_05685	COG0259	pyridoxamine-phosphate oxidase activity
D3A95_05690	COG0832	Belongs to the urease beta subunit family
D3A95_05705	COG0438	transferase activity, transferring glycosyl groups
D3A95_05710	COG2264	protein methyltransferase activity
D3A95_05715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3A95_05755	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
D3A95_05760	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3A95_05775	COG1595	DNA-templated transcription, initiation
D3A95_05780	COG0811	peptide transport
D3A95_05790	COG0457	Tetratricopeptide repeat
D3A95_05790	COG0463	Glycosyl transferase, family 2
D3A95_05800	COG1074	ATP-dependent DNA helicase activity
D3A95_05810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3A95_05815	COG0542	response to heat
D3A95_05830	COG0481	GTPase activity
D3A95_05840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3A95_05865	COG0328	RNA-DNA hybrid ribonuclease activity
D3A95_05870	COG0222	ribosome binding
D3A95_05875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D3A95_05880	COG0081	regulation of translation
D3A95_05885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D3A95_05890	COG0250	Participates in transcription elongation, termination and antitermination
D3A95_05915	COG0675	Transposase, IS605 OrfB family
D3A95_05930	COG2217	Heavy metal translocating P-type atpase
D3A95_05955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D3A95_05960	COG0572	uridine kinase
D3A95_05970	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D3A95_05975	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D3A95_05980	COG0716	FMN binding
D3A95_05990	COG0719	Fe-S assembly protein
D3A95_05995	COG0396	ATPase activity
D3A95_06005	COG3693	PFAM glycoside hydrolase, family 10
D3A95_06010	COG1131	(ABC) transporter
D3A95_06020	COG0497	DNA recombination
D3A95_06030	COG0124	histidyl-tRNA synthetase
D3A95_06050	COG1612	heme a metabolic process
D3A95_06055	COG0109	protoheme IX farnesyltransferase activity
D3A95_06065	COG4221	oxidoreductase activity
D3A95_06075	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D3A95_06090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3A95_06090	COG1754	DNA topoisomerase type I activity
D3A95_06105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3A95_06115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D3A95_06120	COG0557	exoribonuclease II activity
D3A95_06125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3A95_06130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3A95_06135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D3A95_06150	COG3906	Belongs to the UPF0473 family
D3A95_06155	COG1982	Orn Lys Arg decarboxylase major
D3A95_06180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D3A95_06190	COG0675	Transposase, IS605 OrfB family
D3A95_06205	COG0473	3-isopropylmalate dehydrogenase activity
D3A95_06220	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
D3A95_06235	COG0515	serine threonine protein kinase
D3A95_06250	COG0438	transferase activity, transferring glycosyl groups
D3A95_06255	COG0438	transferase activity, transferring glycosyl groups
D3A95_06265	COG0174	glutamine synthetase
D3A95_06270	COG0012	GTP binding
D3A95_06275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D3A95_06280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D3A95_06290	COG0772	Belongs to the SEDS family
D3A95_06310	COG1218	3'(2'),5'-bisphosphate nucleotidase
D3A95_06330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3A95_06340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3A95_06345	COG1543	Belongs to the glycosyl hydrolase 57 family
D3A95_06350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D3A95_06360	COG2308	Evidence 4 Homologs of previously reported genes of
D3A95_06365	COG0525	valine-tRNA ligase activity
D3A95_06370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D3A95_06370	COG0519	Catalyzes the synthesis of GMP from XMP
D3A95_06375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3A95_06385	COG0739	heme binding
D3A95_06390	COG0237	dephospho-CoA kinase activity
D3A95_06395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D3A95_06400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D3A95_06405	COG1413	lyase activity
D3A95_06410	COG1413	lyase activity
D3A95_06415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3A95_06420	COG0237	dephospho-CoA kinase activity
D3A95_06435	COG1573	uracil-dna glycosylase
D3A95_06450	COG2226	methyltransferase
D3A95_06460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D3A95_06470	COG0354	folic acid binding
D3A95_06475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3A95_06480	COG0352	thiamine-phosphate diphosphorylase activity
D3A95_06500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3A95_06515	COG0779	Required for maturation of 30S ribosomal subunits
D3A95_06520	COG0195	Participates in both transcription termination and antitermination
D3A95_06540	COG0681	Belongs to the peptidase S26 family
D3A95_06575	COG0569	domain protein
D3A95_06590	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3A95_06600	COG1012	belongs to the aldehyde dehydrogenase family
D3A95_06610	COG0438	transferase activity, transferring glycosyl groups
D3A95_06610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3A95_06625	COG0431	NADPH-dependent FMN reductase
D3A95_06630	COG0113	porphobilinogen synthase activity
D3A95_06640	COG0024	Methionine aminopeptidase
D3A95_06645	COG0415	Belongs to the DNA photolyase family
D3A95_06655	COG1366	Belongs to the anti-sigma-factor antagonist family
D3A95_06660	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D3A95_06685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D3A95_06690	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3A95_06695	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D3A95_06700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D3A95_06705	COG5002	protein histidine kinase activity
D3A95_06715	COG0159	tryptophan synthase activity
D3A95_06720	COG0772	Belongs to the SEDS family
D3A95_06730	COG4172	Belongs to the ABC transporter superfamily
D3A95_06745	COG0515	serine threonine protein kinase
D3A95_06750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D3A95_06765	COG5002	protein histidine kinase activity
D3A95_06770	COG0475	glutathione-regulated potassium exporter activity
D3A95_06775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D3A95_06780	COG0802	atpase or kinase
D3A95_06785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3A95_06805	COG2884	Cell division ATP-binding protein ftsE
D3A95_06840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3A95_06845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D3A95_06855	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D3A95_06860	COG0316	Belongs to the HesB IscA family
D3A95_06865	COG1090	epimerase
D3A95_06875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D3A95_06890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3A95_06905	COG0077	Prephenate dehydratase
D3A95_06910	COG0686	Belongs to the AlaDH PNT family
D3A95_06915	COG0575	Belongs to the CDS family
D3A95_06930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D3A95_06945	COG0411	ABC transporter
D3A95_06955	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
D3A95_06965	COG1725	Transcriptional regulator
D3A95_06970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D3A95_06975	COG0483	inositol monophosphate 1-phosphatase activity
D3A95_06995	COG0405	Gamma-glutamyltransferase
D3A95_07000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3A95_07005	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_07015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D3A95_07020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3A95_07025	COG1546	Belongs to the CinA family
D3A95_07025	COG1058	Belongs to the CinA family
D3A95_07040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D3A95_07100	COG0659	secondary active sulfate transmembrane transporter activity
D3A95_07105	COG2094	Belongs to the DNA glycosylase MPG family
D3A95_07115	COG0484	heat shock protein binding
D3A95_07120	COG0443	Heat shock 70 kDa protein
D3A95_07130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3A95_07130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3A95_07140	COG0739	heme binding
D3A95_07145	COG1587	Uroporphyrinogen-III synthase
D3A95_07155	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D3A95_07160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D3A95_07165	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D3A95_07175	COG2302	S4 RNA-binding domain
D3A95_07190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3A95_07195	COG0573	inorganic phosphate transmembrane transporter activity
D3A95_07200	COG0581	inorganic phosphate transmembrane transporter activity
D3A95_07205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3A95_07235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D3A95_07235	COG0189	ligase activity
D3A95_07265	COG0419	ATPase involved in DNA repair
D3A95_07270	COG2304	oxidoreductase activity
D3A95_07280	COG4221	oxidoreductase activity
D3A95_07295	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D3A95_07295	COG0546	phosphoglycolate phosphatase activity
D3A95_07305	COG2205	protein histidine kinase activity
D3A95_07325	COG0330	HflC and HflK could
D3A95_07330	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3A95_07340	COG0047	phosphoribosylformylglycinamidine synthase activity
D3A95_07355	COG0791	NLP P60 protein
D3A95_07355	COG0741	lytic transglycosylase activity
D3A95_07360	COG0516	GMP reductase activity
D3A95_07370	COG0751	glycine-tRNA ligase activity
D3A95_07375	COG1185	polyribonucleotide nucleotidyltransferase activity
D3A95_07390	COG1575	Belongs to the MenA family. Type 1 subfamily
D3A95_07400	COG0456	acetyltransferase
D3A95_07405	COG0778	Nitroreductase
D3A95_07410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D3A95_07415	COG0745	RESPONSE REGULATOR receiver
D3A95_07420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D3A95_07425	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D3A95_07430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D3A95_07445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D3A95_07450	COG3781	membrane
D3A95_07460	COG0582	viral genome integration into host DNA
D3A95_07475	COG0443	Heat shock 70 kDa protein
D3A95_07480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D3A95_07495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D3A95_07510	COG2815	serine threonine protein kinase
D3A95_07510	COG0515	serine threonine protein kinase
D3A95_07520	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3A95_07525	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D3A95_07535	COG1381	Involved in DNA repair and RecF pathway recombination
D3A95_07545	COG2208	phosphoserine phosphatase activity
D3A95_07555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D3A95_07565	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D3A95_07570	COG0631	protein serine/threonine phosphatase activity
D3A95_07580	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
D3A95_07590	COG0793	Belongs to the peptidase S41A family
D3A95_07640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D3A95_07655	COG2255	four-way junction helicase activity
D3A95_07660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D3A95_07665	COG0724	RNA recognition motif
D3A95_07670	COG0482	sulfurtransferase activity
D3A95_07685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3A95_07690	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
D3A95_07695	COG0450	alkyl hydroperoxide reductase
D3A95_07705	COG0628	permease
D3A95_07725	COG0006	proline dipeptidase activity
D3A95_07730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3A95_07735	COG0776	regulation of translation
D3A95_07740	COG0126	phosphoglycerate kinase activity
D3A95_07745	COG0589	response to stress
D3A95_07765	COG0135	phosphoribosylanthranilate isomerase activity
D3A95_07780	COG0469	pyruvate kinase activity
D3A95_07785	COG0523	cobalamin synthesis protein
D3A95_07860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D3A95_07865	COG3118	belongs to the thioredoxin family
D3A95_07870	COG4399	Belongs to the UPF0754 family
D3A95_07880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3A95_07885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3A95_07890	COG5505	Protein of unknown function (DUF819)
D3A95_07905	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D3A95_07915	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
D3A95_07960	COG4279	zinc finger
D3A95_07965	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D3A95_07990	COG1657	PFAM Prenyltransferase squalene oxidase
D3A95_07995	COG4783	chaperone-mediated protein folding
D3A95_08015	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D3A95_08025	COG0556	nucleotide-excision repair
D3A95_08035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D3A95_08045	COG0583	DNA-binding transcription factor activity
D3A95_08055	COG0170	dolichyl monophosphate biosynthetic process
D3A95_08060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D3A95_08075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D3A95_08080	COG0436	Aminotransferase
D3A95_08110	COG0495	leucyl-tRNA aminoacylation
D3A95_08120	COG0489	protein tyrosine kinase activity
D3A95_08135	COG0438	transferase activity, transferring glycosyl groups
D3A95_08140	COG0438	transferase activity, transferring glycosyl groups
D3A95_08150	COG1216	Glycosyl transferase, family 2
D3A95_08170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_08195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D3A95_08205	COG3118	belongs to the thioredoxin family
D3A95_08235	COG0714	Associated with various cellular activities
D3A95_08245	COG0058	SHG alpha-glucan phosphorylase activity
D3A95_08255	COG3932	Exopolysaccharide synthesis, ExoD
D3A95_08275	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D3A95_08280	COG0539	negative regulation of cytoplasmic translation
D3A95_08285	COG1970	mechanosensitive ion channel activity
D3A95_08320	COG3158	transport of potassium into the cell
D3A95_08325	COG0436	Aminotransferase
D3A95_08330	COG0371	Dehydrogenase
D3A95_08340	COG2022	thiamine diphosphate biosynthetic process
D3A95_08340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3A95_08350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3A95_08355	COG0587	DNA-directed DNA polymerase activity
D3A95_08375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3A95_08380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D3A95_08385	COG3443	Belongs to the bacterial solute-binding protein 9 family
D3A95_08385	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3A95_08390	COG1121	(ABC) transporter
D3A95_08410	COG0596	Alpha beta hydrolase
D3A95_08420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3A95_08425	COG0587	DNA-directed DNA polymerase activity
D3A95_08450	COG0275	rRNA processing
D3A95_08460	COG0768	penicillin binding
D3A95_08475	COG0582	viral genome integration into host DNA
D3A95_08500	COG3385	transposase activity
D3A95_08505	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D3A95_08515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D3A95_08540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3A95_08545	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D3A95_08560	COG0824	Thioesterase
D3A95_08570	COG0719	Fe-S assembly protein
D3A95_08590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D3A95_08595	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D3A95_08605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3A95_08615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3A95_08620	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D3A95_08625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3A95_08630	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D3A95_08635	COG1959	2 iron, 2 sulfur cluster binding
D3A95_08640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3A95_08660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D3A95_08665	COG1834	amidinotransferase
D3A95_08670	COG0544	peptidyl-prolyl cis-trans isomerase activity
D3A95_08675	COG0740	serine-type endopeptidase activity
D3A95_08680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D3A95_08685	COG4221	oxidoreductase activity
D3A95_08700	COG2226	methyltransferase
D3A95_08705	COG0589	response to stress
D3A95_08720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D3A95_08725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3A95_08725	COG2022	thiamine diphosphate biosynthetic process
D3A95_08735	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D3A95_08740	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D3A95_08740	COG0237	dephospho-CoA kinase activity
D3A95_08745	COG0745	RESPONSE REGULATOR receiver
D3A95_08770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D3A95_08775	COG0463	Glycosyl transferase, family 2
D3A95_08785	COG0436	Aminotransferase
D3A95_08795	COG1940	carbohydrate kinase activity
D3A95_08800	COG1316	TRANSCRIPTIONal
D3A95_08805	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D3A95_08815	COG5002	protein histidine kinase activity
D3A95_08820	COG0728	peptidoglycan biosynthetic process
D3A95_08825	COG0592	DNA-directed DNA polymerase activity
D3A95_08835	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
D3A95_08845	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D3A95_08870	COG1376	ErfK ybiS ycfS ynhG family protein
D3A95_08880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3A95_08890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3A95_08895	COG2252	PERMEase
D3A95_08920	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D3A95_08925	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D3A95_08935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3A95_08940	COG2052	Domain of unknown function (DUF370)
D3A95_08970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D3A95_08975	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D3A95_09005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D3A95_09010	COG0793	Belongs to the peptidase S41A family
D3A95_09015	COG3659	wide pore channel activity
D3A95_09020	COG2197	response regulator
D3A95_09025	COG4636	protein conserved in cyanobacteria
D3A95_09050	COG0284	orotidine-5'-phosphate decarboxylase activity
D3A95_09065	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D3A95_09075	COG2385	sporulation resulting in formation of a cellular spore
D3A95_09085	COG0233	cytoplasmic translational termination
D3A95_09090	COG0528	UMP kinase activity
D3A95_09100	COG0745	RESPONSE REGULATOR receiver
D3A95_09120	COG1192	Involved in chromosome partitioning
D3A95_09125	COG0542	response to heat
D3A95_09140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3A95_09190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D3A95_09195	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
D3A95_09205	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
D3A95_09210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D3A95_09215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3A95_09220	COG3536	Protein conserved in bacteria
D3A95_09230	COG5001	Diguanylate cyclase
D3A95_09250	COG1193	negative regulation of DNA recombination
D3A95_09255	COG0017	Asparaginyl-tRNA synthetase
D3A95_09260	COG0475	glutathione-regulated potassium exporter activity
D3A95_09260	COG0589	response to stress
D3A95_09265	COG0133	tryptophan synthase activity
D3A95_09285	COG0612	Peptidase, M16
D3A95_09295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D3A95_09300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D3A95_09305	COG0735	belongs to the Fur family
D3A95_09315	COG1619	proteins homologs of microcin C7 resistance protein MccF
D3A95_09320	COG0675	Transposase, IS605 OrfB family
D3A95_09335	COG1007	ATP synthesis coupled electron transport
D3A95_09340	COG0425	Belongs to the sulfur carrier protein TusA family
D3A95_09340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3A95_09345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3A95_09350	COG0318	PFAM AMP-dependent synthetase and ligase
D3A95_09350	COG0204	Acyl-transferase
D3A95_09355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3A95_09360	COG0228	four-way junction DNA binding
D3A95_09370	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D3A95_09375	COG1702	phosphate starvation-inducible protein PhoH
D3A95_09395	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3A95_09405	COG2205	protein histidine kinase activity
D3A95_09435	COG2832	Protein of unknown function (DUF454)
D3A95_09445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D3A95_09455	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D3A95_09470	COG2211	Major facilitator Superfamily
D3A95_09475	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
D3A95_09480	COG2954	triphosphatase activity
D3A95_09485	COG1473	amidohydrolase
D3A95_09510	COG4956	integral membrane protein (PIN domain superfamily)
D3A95_09530	COG0804	urea catabolic process
D3A95_09540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3A95_09560	COG0194	GDP metabolic process
D3A95_09565	COG0848	biopolymer transport protein
D3A95_09570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D3A95_09575	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D3A95_09580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3A95_09590	COG0420	3'-5' exonuclease activity
D3A95_09615	COG2022	thiamine diphosphate biosynthetic process
D3A95_09625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D3A95_09650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3A95_09655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3A95_09695	COG0628	permease
D3A95_09700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D3A95_09715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3A95_09740	COG0343	queuine tRNA-ribosyltransferase activity
D3A95_09745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D3A95_09750	COG0088	Forms part of the polypeptide exit tunnel
D3A95_09755	COG0089	rRNA binding
D3A95_09760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D3A95_09765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D3A95_09770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D3A95_09775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D3A95_09780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D3A95_09785	COG0255	Belongs to the universal ribosomal protein uL29 family
D3A95_09790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D3A95_09795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D3A95_09800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D3A95_09805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D3A95_09810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D3A95_09815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D3A95_09820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D3A95_09825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D3A95_09830	COG0200	Binds to the 23S rRNA
D3A95_09835	COG0201	protein transport
D3A95_09840	COG0563	adenylate kinase activity
D3A95_09845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D3A95_09850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D3A95_09855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D3A95_09860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D3A95_09865	COG0202	RNA polymerase activity
D3A95_09870	COG0203	ribosomal protein L17
D3A95_09875	COG0101	tRNA pseudouridine synthase activity
D3A95_09880	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D3A95_09885	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D3A95_09890	COG0254	rRNA binding
D3A95_09915	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
D3A95_09925	COG1104	cysteine desulfurase activity
D3A95_09940	COG0484	heat shock protein binding
D3A95_09955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D3A95_09985	COG0066	3-isopropylmalate dehydratase activity
D3A95_09990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D3A95_10010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D3A95_10015	COG1468	defense response to virus
D3A95_10015	COG1518	maintenance of DNA repeat elements
D3A95_10020	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
D3A95_10030	COG1203	CRISPR-associated helicase, Cas3
D3A95_10040	COG1857	crispr-associated protein
D3A95_10070	COG5398	heme oxygenase
D3A95_10075	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D3A95_10105	COG3150	esterase
D3A95_10110	COG2226	methyltransferase
D3A95_10115	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3A95_10115	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3A95_10135	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D3A95_10140	COG0443	Heat shock 70 kDa protein
D3A95_10155	COG3264	Mechanosensitive ion channel
D3A95_10155	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D3A95_10160	COG0792	nuclease activity
D3A95_10165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D3A95_10175	COG3977	Valine--pyruvate aminotransferase
D3A95_10180	COG0675	Transposase, IS605 OrfB family
D3A95_10190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3A95_10200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D3A95_10205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D3A95_10210	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D3A95_10215	COG0049	tRNA binding
D3A95_10220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D3A95_10225	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D3A95_10230	COG0051	transcription antitermination factor activity, RNA binding
D3A95_10240	COG0322	excinuclease ABC activity
D3A95_10250	COG0347	Belongs to the P(II) protein family
D3A95_10260	COG1742	UPF0060 membrane protein
D3A95_10265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D3A95_10270	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D3A95_10275	COG3842	ATPase activity
D3A95_10280	COG0142	geranyltranstransferase activity
D3A95_10290	COG0740	serine-type endopeptidase activity
D3A95_10300	COG0019	diaminopimelate decarboxylase activity
D3A95_10310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D3A95_10315	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D3A95_10320	COG0083	homoserine kinase activity
D3A95_10330	COG0489	protein tyrosine kinase activity
D3A95_10340	COG1136	(ABC) transporter
D3A95_10355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3A95_10360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D3A95_10360	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D3A95_10380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3A95_10415	COG4372	Transposase
D3A95_10425	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D3A95_10445	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D3A95_10450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3A95_10455	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3A95_10460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D3A95_10475	COG1215	transferase activity, transferring glycosyl groups
D3A95_10480	COG1215	transferase activity, transferring glycosyl groups
D3A95_10490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D3A95_10500	COG4636	protein conserved in cyanobacteria
D3A95_10505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D3A95_10510	COG2843	Capsule synthesis protein
D3A95_10515	COG0517	IMP dehydrogenase activity
D3A95_10515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D3A95_10515	COG0617	tRNA 3'-terminal CCA addition
D3A95_10525	COG0616	signal peptide processing
D3A95_10540	COG1166	arginine decarboxylase activity
D3A95_10545	COG0439	Biotin carboxylase
D3A95_10550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3A95_10555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3A95_10560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D3A95_10575	COG4783	chaperone-mediated protein folding
D3A95_10580	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D3A95_10600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D3A95_10605	COG0730	response to heat
D3A95_10610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3A95_10620	COG0277	FAD linked oxidase domain protein
D3A95_10645	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D3A95_10645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3A95_10655	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D3A95_10660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3A95_10670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3A95_10675	COG0037	tRNA processing
D3A95_10680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3A95_10690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3A95_10695	COG5001	Diguanylate cyclase
D3A95_10700	COG0336	Belongs to the RNA methyltransferase TrmD family
D3A95_10715	COG0789	Transcriptional regulator
D3A95_10730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3A95_10735	COG0793	Belongs to the peptidase S41A family
D3A95_10740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D3A95_10750	COG2226	methyltransferase
D3A95_10755	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3A95_10755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3A95_10760	COG1271	oxidase subunit
D3A95_10765	COG1294	oxidase, subunit
D3A95_10780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3A95_10785	COG1215	transferase activity, transferring glycosyl groups
D3A95_10800	COG0653	protein targeting
D3A95_10810	COG0739	heme binding
D3A95_10815	COG1797	cobyrinic acid a,c-diamide synthase activity
D3A95_10825	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
D3A95_10840	COG0675	Transposase, IS605 OrfB family
D3A95_10850	COG0003	Pfam Anion-transporting ATPase
D3A95_10855	COG4181	ATPase activity
D3A95_10865	COG0151	Belongs to the GarS family
D3A95_10885	COG2890	protein-(glutamine-N5) methyltransferase activity
D3A95_10895	COG0697	spore germination
D3A95_10905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3A95_10910	COG5002	protein histidine kinase activity
D3A95_10920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D3A95_10925	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D3A95_10930	COG0215	cysteine-tRNA ligase activity
D3A95_10935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D3A95_10940	COG2154	pterin-4-alpha-carbinolamine dehydratase
D3A95_10955	COG0681	Belongs to the peptidase S26 family
D3A95_10960	COG3001	Fructosamine kinase
D3A95_10970	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_10980	COG0651	ATP synthesis coupled electron transport
D3A95_11010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D3A95_11020	COG0114	fumarate hydratase activity
D3A95_11025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3A95_11060	COG0589	response to stress
D3A95_11065	COG0457	Tetratricopeptide repeat
D3A95_11070	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D3A95_11090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D3A95_11095	COG2211	Major facilitator Superfamily
D3A95_11100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3A95_11105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3A95_11125	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
D3A95_11130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D3A95_11145	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
D3A95_11170	COG1850	ribulose-bisphosphate carboxylase activity
D3A95_11185	COG0525	valine-tRNA ligase activity
D3A95_11190	COG1028	Short-chain dehydrogenase reductase Sdr
D3A95_11205	COG2319	Wd-40 repeat
D3A95_11205	COG1672	PFAM Archaeal ATPase
D3A95_11215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D3A95_11220	COG0837	glucose binding
D3A95_11235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D3A95_11245	COG0629	single-stranded DNA binding
D3A95_11275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D3A95_11285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3A95_11290	COG0484	heat shock protein binding
D3A95_11295	COG0131	Imidazoleglycerol-phosphate dehydratase
D3A95_11310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D3A95_11325	COG2814	Major facilitator Superfamily
D3A95_11330	COG1672	PFAM Archaeal ATPase
D3A95_11335	COG4243	Vitamin k epoxide reductase
D3A95_11345	COG0009	L-threonylcarbamoyladenylate synthase
D3A95_11350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3A95_11355	COG0038	chloride channel
D3A95_11365	COG0628	permease
D3A95_11370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D3A95_11375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D3A95_11385	COG0644	oxidoreductase
D3A95_11390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D3A95_11395	COG1132	(ABC) transporter
D3A95_11405	COG0589	response to stress
D3A95_11415	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D3A95_11425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3A95_11430	COG0134	indole-3-glycerol-phosphate synthase activity
D3A95_11435	COG3046	protein related to deoxyribodipyrimidine photolyase
D3A95_11445	COG1446	asparaginase
D3A95_11450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_11465	COG1640	4-alpha-glucanotransferase
D3A95_11480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3A95_11485	COG0137	argininosuccinate synthase activity
D3A95_11500	COG0617	tRNA 3'-terminal CCA addition
D3A95_11510	COG0166	Belongs to the GPI family
D3A95_11515	COG1073	alpha beta
D3A95_11520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_11525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3A95_11535	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D3A95_11570	COG0251	oxidation-reduction process
D3A95_11575	COG2885	chlorophyll binding
D3A95_11580	COG2885	chlorophyll binding
D3A95_11585	COG0668	transmembrane transport
D3A95_11615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3A95_11620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3A95_11630	COG1968	undecaprenyl-diphosphatase activity
D3A95_11645	COG3854	ATPases associated with a variety of cellular activities
D3A95_11655	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D3A95_11675	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D3A95_11720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3A95_11750	COG0484	heat shock protein binding
D3A95_11755	COG1175	transmembrane transport
D3A95_11760	COG0505	Belongs to the CarA family
D3A95_11765	COG1420	regulation of RNA biosynthetic process
D3A95_11775	COG0297	glycogen (starch) synthase activity
D3A95_11780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D3A95_11785	COG0574	Belongs to the PEP-utilizing enzyme family
D3A95_11785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3A95_11795	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
D3A95_11810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3A95_11825	COG0457	Tetratricopeptide repeat
D3A95_11830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3A95_11835	COG1615	UPF0182 protein
D3A95_11850	COG1126	abc transporter atp-binding protein
D3A95_11875	COG0762	integral membrane protein
D3A95_11910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D3A95_11915	COG1366	Belongs to the anti-sigma-factor antagonist family
D3A95_11925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D3A95_11930	COG2205	protein histidine kinase activity
D3A95_11935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3A95_11950	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
D3A95_11950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3A95_11955	COG1562	ergosterol biosynthetic process
D3A95_11960	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
D3A95_11965	COG0540	Belongs to the ATCase OTCase family
D3A95_11975	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3A95_11980	COG0196	riboflavin kinase activity
D3A95_11985	COG0714	Associated with various cellular activities
D3A95_12000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D3A95_12005	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D3A95_12030	COG0138	bifunctional purine biosynthesis protein purh
D3A95_12035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D3A95_12040	COG1175	transmembrane transport
D3A95_12065	COG1357	PFAM Pentapeptide repeats (8 copies)
D3A95_12065	COG0515	serine threonine protein kinase
D3A95_12070	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D3A95_12075	COG0564	pseudouridine synthase activity
D3A95_12100	COG0358	DNA primase activity
D3A95_12105	COG0205	6-phosphofructokinase activity
D3A95_12110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3A95_12115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D3A95_12120	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D3A95_12125	COG5322	oxidoreductase activity
D3A95_12130	COG0825	malonyl-CoA metabolic process
D3A95_12135	COG0300	oxidoreductase activity
D3A95_12140	COG0302	gtp cyclohydrolase
D3A95_12165	COG1994	Peptidase M50
D3A95_12165	COG0517	IMP dehydrogenase activity
D3A95_12190	COG0335	large ribosomal subunit rRNA binding
D3A95_12195	COG0424	maF-like protein
D3A95_12200	COG1022	Amp-dependent synthetase and ligase
D3A95_12210	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3A95_12215	COG1122	ATPase activity
D3A95_12225	COG0028	Belongs to the TPP enzyme family
D3A95_12230	COG0511	ligase activity, forming carbon-carbon bonds
D3A95_12235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D3A95_12240	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D3A95_12250	COG1070	Carbohydrate kinase
D3A95_12255	COG1160	GTP binding
D3A95_12270	COG0649	NAD binding
D3A95_12275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D3A95_12285	COG2010	Cytochrome c
D3A95_12290	COG2010	Cytochrome c
D3A95_12305	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D3A95_12315	COG0360	Binds together with S18 to 16S ribosomal RNA
D3A95_12320	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3A95_12325	COG0175	sulfate reduction
D3A95_12330	COG0752	glycyl-tRNA synthetase alpha subunit
D3A95_12335	COG0726	polysaccharide deacetylase
D3A95_12345	COG0163	prenyltransferase activity
D3A95_12355	COG0702	epimerase
D3A95_12365	COG1410	methionine synthase
D3A95_12365	COG0646	methionine synthase
D3A95_12385	COG2010	Cytochrome c
D3A95_12395	COG0463	Glycosyl transferase, family 2
D3A95_12395	COG0457	Tetratricopeptide repeat
D3A95_12400	COG2205	protein histidine kinase activity
D3A95_12405	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D3A95_12415	COG0745	RESPONSE REGULATOR receiver
D3A95_12425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D3A95_12430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D3A95_12435	COG0489	protein tyrosine kinase activity
D3A95_12440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D3A95_12440	COG0519	Catalyzes the synthesis of GMP from XMP
D3A95_12450	COG4572	Cation transport regulator
D3A95_12455	COG0305	Participates in initiation and elongation during chromosome replication
D3A95_12455	COG1372	Participates in initiation and elongation during chromosome replication
D3A95_12455	COG0305	Participates in initiation and elongation during chromosome replication
D3A95_12455	COG1372	Participates in initiation and elongation during chromosome replication
D3A95_12460	COG0359	binds to the 23S rRNA
D3A95_12480	COG1555	photosystem II stabilization
D3A95_12485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D3A95_12555	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D3A95_12560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D3A95_12560	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D3A95_12565	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D3A95_12570	COG0372	Belongs to the citrate synthase family
D3A95_12575	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D3A95_12585	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D3A95_12595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3A95_12600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3A95_12605	COG1116	anion transmembrane transporter activity
D3A95_12605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3A95_12610	COG1116	anion transmembrane transporter activity
D3A95_12615	COG0243	molybdopterin cofactor binding
D3A95_12630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D3A95_12635	COG0583	DNA-binding transcription factor activity
D3A95_12640	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
D3A95_12645	COG0314	molybdopterin synthase activity
D3A95_12655	COG0746	molybdenum cofactor guanylyltransferase activity
D3A95_12655	COG0315	cyclic pyranopterin monophosphate synthase activity
D3A95_12660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D3A95_12665	COG0303	'Molybdopterin
D3A95_12670	COG0830	nickel cation binding
D3A95_12675	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
D3A95_12680	COG0784	Response regulator, receiver
D3A95_12680	COG2205	protein histidine kinase activity
D3A95_12685	COG0067	glutamate synthase
D3A95_12685	COG0069	glutamate synthase activity
D3A95_12685	COG0070	glutamate synthase
D3A95_12700	COG0863	Belongs to the N(4) N(6)-methyltransferase family
D3A95_12715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3A95_12720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3A95_12735	COG0426	domain, Protein
D3A95_12735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3A95_12745	COG0419	ATPase involved in DNA repair
D3A95_12750	COG2027	D-alanyl-D-alanine carboxypeptidase
D3A95_12770	COG0395	ABC-type sugar transport system, permease component
D3A95_12775	COG1136	(ABC) transporter
D3A95_12775	COG0577	efflux transmembrane transporter activity
D3A95_12780	COG0193	aminoacyl-tRNA hydrolase activity
D3A95_12785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3A95_12805	COG0542	response to heat
D3A95_12825	COG0745	RESPONSE REGULATOR receiver
D3A95_12855	COG0438	transferase activity, transferring glycosyl groups
D3A95_12885	COG0367	asparagine synthase
D3A95_12900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D3A95_12910	COG0489	protein tyrosine kinase activity
D3A95_12920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D3A95_12925	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D3A95_12945	COG0121	glutamine amidotransferase
D3A95_12955	COG1304	FMN binding
D3A95_12960	COG0644	oxidoreductase
D3A95_12965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3A95_12970	COG0793	Belongs to the peptidase S41A family
D3A95_12980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D3A95_12995	COG2340	Cysteine-rich secretory protein family
D3A95_13000	COG0459	protein refolding
D3A95_13005	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
D3A95_13005	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
D3A95_13025	COG0310	cobalt ion transport
D3A95_13040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3A95_13050	COG0412	Dienelactone hydrolase
D3A95_13055	COG3063	Type IV pilus biogenesis stability protein PilW
D3A95_13065	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D3A95_13080	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_13085	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3A95_13100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D3A95_13115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3A95_13120	COG1376	ErfK ybiS ycfS ynhG family protein
D3A95_13135	COG2268	Band 7 protein
D3A95_13160	COG3596	GTP binding
D3A95_13180	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D3A95_13185	COG0271	Belongs to the BolA IbaG family
D3A95_13210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3A95_13315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3A95_13345	COG0842	Transport permease protein
D3A95_13345	COG1716	ATPase activity
D3A95_13345	COG1131	(ABC) transporter
D3A95_13350	COG1331	Highly conserved protein containing a thioredoxin domain
D3A95_13355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D3A95_13395	COG0469	pyruvate kinase activity