locus-tag	class	description
T2812B_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
T2812B_00010	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
T2812B_00025	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
T2812B_00045	ENOG4105C8Q	Methyl-accepting chemotaxis
T2812B_00065	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
T2812B_00070	ENOG41080JC	Protein of unknown function DUF47
T2812B_00075	ENOG4105DXN	mazG family
T2812B_00085	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
T2812B_00090	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
T2812B_00095	ENOG4105D00	flagellar biosynthetic protein flhB
T2812B_00100	ENOG4105D7B	Flagellar biosynthesis protein flha
T2812B_00105	ENOG4105FZW	flagellar biosynthesis regulator FlhF
T2812B_00120	ENOG4107PHP	CheC --inhibitor of MCP methylation
T2812B_00125	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
T2812B_00130	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
T2812B_00155	ENOG4105MCT	stage V sporulation protein S
T2812B_00160	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
T2812B_00165	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
T2812B_00175	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
T2812B_00180	ENOG4105CJW	magnesium transporter
T2812B_00185	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
T2812B_00190	ENOG4105DZP	Membrane-associated zinc metalloprotease
T2812B_00195	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
T2812B_00205	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
T2812B_00210	ENOG4105BZ4	penicillin-binding protein
T2812B_00225	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
T2812B_00235	ENOG4105CVG	Homoserine O-transsuccinylase
T2812B_00240	ENOG4105D9Q	decarboxylase (Beta subunit)
T2812B_00250	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
T2812B_00275	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
T2812B_00280	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
T2812B_00290	ENOG4105CJN	penicillin-binding protein
T2812B_00300	ENOG4108JU3	Alkyl hydroperoxide reductase
T2812B_00320	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
T2812B_00325	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
T2812B_00330	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
T2812B_00335	ENOG4107VRQ	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
T2812B_00340	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
T2812B_00345	ENOG4107Z7W	Preprotein translocase YajC subunit
T2812B_00355	ENOG4105DTN	riboflavin biosynthesis protein ribF
T2812B_00360	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
T2812B_00365	ENOG41084NJ	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
T2812B_00370	ENOG4108HU6	Metal dependent phosphohydrolase
T2812B_00375	ENOG4105BZU	Histidine kinase
T2812B_00380	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
T2812B_00385	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
T2812B_00390	ENOG41085Z1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
T2812B_00395	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
T2812B_00400	ENOG4105CQW	ribosome biogenesis GTPase YqeH
T2812B_00405	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
T2812B_00410	ENOG4105KG3	cytidine deaminase
T2812B_00415	ENOG4108JU5	Magnesium and cobalt efflux protein
T2812B_00420	ENOG41082VF	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
T2812B_00425	ENOG4105CCS	Glutamate formiminotransferase
T2812B_00430	ENOG4107YTP	response regulator receiver protein
T2812B_00445	ENOG4105CNI	cell division protein FtsW
T2812B_00455	ENOG4107QHF	type ii secretion system protein e
T2812B_00460	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
T2812B_00465	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
T2812B_00475	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
T2812B_00485	ENOG4107Z5F	Aminotransferase class IV
T2812B_00490	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
T2812B_00500	ENOG4105DE4	1-phosphofructokinase
T2812B_00505	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
T2812B_00515	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
T2812B_00525	ENOG4108IG5	Transcriptional regulator
T2812B_00530	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
T2812B_00535	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
T2812B_00540	ENOG4107QW4	alcohol dehydrogenase
T2812B_00550	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
T2812B_00565	ENOG4105UQX	Mate efflux family protein
T2812B_00575	ENOG4105CNW	domain protein
T2812B_00580	ENOG4105CE4	GlcNAc 6-P deacetylase
T2812B_00585	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
T2812B_00590	ENOG4105DRS	transport system, permease
T2812B_00610	ENOG4105E2R	ROK family
T2812B_00615	ENOG4105D3R	alkyl hydroperoxide reductase
T2812B_00625	ENOG4105ESV	Glycosyl transferase, family 4
T2812B_00630	ENOG4107RU2	Histidinol phosphate phosphatase, HisJ family
T2812B_00635	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
T2812B_00640	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
T2812B_00645	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
T2812B_00650	ENOG4105EA8	2-Nitropropane dioxygenase
T2812B_00655	ENOG4105VKD	bioY protein
T2812B_00665	ENOG4108N5B	2-phosphosulfolactate phosphatase
T2812B_00685	ENOG4105CJ1	ABC, transporter
T2812B_00695	ENOG410816Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
T2812B_00700	ENOG4107ZCS	Phosphomethylpyrimidine kinase
T2812B_00710	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
T2812B_00715	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
T2812B_00725	ENOG41074CX	linocin_m18 bacteriocin protein
T2812B_00780	ENOG4105MA4	psp1 domain protein
T2812B_00785	ENOG4107QRG	dna polymerase iii
T2812B_00790	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
T2812B_00800	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
T2812B_00805	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
T2812B_00815	ENOG4105CZV	ABC transporter
T2812B_00825	ENOG4105K8R	UPF0145 protein
T2812B_00830	ENOG4105CE9	30S ribosomal protein S2
T2812B_00860	ENOG4107TVC	Glycosyl transferase, family 2
T2812B_00865	ENOG4105K64	Glycosyl transferase, family 2
T2812B_00870	ENOG4105CNW	domain protein
T2812B_00875	ENOG4108IFG	nitrite reductase, (NAD(P)H)
T2812B_00880	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
T2812B_00885	ENOG4107V4V	glycoside hydrolase family 4
T2812B_00890	ENOG4105BZU	Histidine kinase
T2812B_00900	ENOG4105DBI	uridine monophosphokinase
T2812B_00915	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
T2812B_00920	ENOG4105CN1	protease
T2812B_00935	ENOG4105BZF	Glycosyl transferase (Group 1
T2812B_00945	ENOG4107S1Q	Phosphatase
T2812B_00950	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
T2812B_00955	ENOG4105C22	threonyL-tRNA synthetase
T2812B_00960	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
T2812B_00975	ENOG4105DG6	mannose-6-phosphate isomerase
T2812B_00985	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
T2812B_01000	ENOG4105WPN	DNA integration recombination invertion protein
T2812B_01005	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
T2812B_01010	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
T2812B_01020	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
T2812B_01025	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
T2812B_01045	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
T2812B_01050	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
T2812B_01055	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
T2812B_01060	ENOG4105C8N	cysteinyl-tRNA synthetase
T2812B_01065	ENOG4105YFD	chemotaxis, protein
T2812B_01070	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
T2812B_01080	ENOG4105D8K	carboxyl transferase
T2812B_01115	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
T2812B_01120	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
T2812B_01125	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
T2812B_01135	ENOG4105C19	ABC transporter
T2812B_01140	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
T2812B_01145	ENOG4105CEV	competence damage-inducible protein
T2812B_01150	ENOG4105CBS	Chea signal transduction histidine kinase
T2812B_01155	ENOG4105YVF	chew protein
T2812B_01160	ENOG4107YTP	response regulator receiver protein
T2812B_01170	ENOG4105CN7	Flagellar biosynthetic protein FliP
T2812B_01185	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
T2812B_01190	ENOG4107XYV	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
T2812B_01200	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
T2812B_01215	ENOG4105BZA	Phosphoglycerate kinase
T2812B_01220	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
T2812B_01225	ENOG41085TI	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
T2812B_01230	ENOG4105C6E	dna polymerase iii
T2812B_01260	ENOG4105DD5	Flagellar motor switch protein
T2812B_01265	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
T2812B_01275	ENOG4105ER2	Ompa motb domain protein
T2812B_01280	ENOG4105E14	MotA TolQ exbB proton channel
T2812B_01285	ENOG41068WV	flagellar FlbD family protein
T2812B_01290	ENOG4105BZE	flagellar hook protein, FlgE
T2812B_01325	ENOG4105F8V	Hydrolase, tatD family
T2812B_01335	ENOG4105C6T	cysteine synthase
T2812B_01350	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
T2812B_01360	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
T2812B_01365	ENOG4105VCQ	rubredoxin
T2812B_01370	ENOG4108YZ8	Superoxide reductase
T2812B_01375	ENOG4108RAC	Rubrerythrin
T2812B_01380	ENOG4106A7E	Transcriptional regulator
T2812B_01385	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
T2812B_01390	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
T2812B_01395	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
T2812B_01405	ENOG4105J7I	hydrolase
T2812B_01420	ENOG41082Q0	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
T2812B_01425	ENOG4107S7H	nh(3)-dependent nad( ) synthetase
T2812B_01455	ENOG4105DAY	polysaccharide export protein
T2812B_01480	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
T2812B_01530	ENOG4107RA4	Glycosyl transferase (Group 1
T2812B_01550	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
T2812B_01560	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
T2812B_01575	ENOG4107RA4	Glycosyl transferase (Group 1
T2812B_01620	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
T2812B_01635	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
T2812B_01645	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
T2812B_01650	ENOG4108UUM	single-stranded DNA-binding protein
T2812B_01655	ENOG41083EQ	Binds together with S18 to 16S ribosomal RNA (By similarity)
T2812B_01680	ENOG4105DRS	transport system, permease
T2812B_01700	ENOG4105C7N	Xanthine uracil vitamin C permease
T2812B_01705	ENOG4105EAB	amino acid AbC transporter
T2812B_01710	ENOG4105E5Q	amino acid AbC transporter
T2812B_01720	ENOG4105CJN	penicillin-binding protein
T2812B_01730	ENOG4105DFF	Rod shape-determining protein mreb
T2812B_01735	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
T2812B_01740	ENOG410631K	Membrane
T2812B_01755	ENOG4107QQG	Dehydrogenase
T2812B_01770	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
T2812B_01775	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
T2812B_01780	ENOG4105II7	pyrroline-5-carboxylate reductase
T2812B_01785	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
T2812B_01790	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
T2812B_01795	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
T2812B_01800	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
T2812B_01805	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
T2812B_01810	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
T2812B_01815	ENOG4105C0H	protease
T2812B_01820	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
T2812B_01835	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
T2812B_01845	ENOG4107ZMQ	sugar fermentation stimulation protein
T2812B_01875	ENOG4105D7N	magnesium and cobalt transport protein CorA
T2812B_01890	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
T2812B_01900	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
T2812B_01905	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
T2812B_01910	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
T2812B_01915	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
T2812B_01920	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
T2812B_01925	ENOG4105C01	Dihydroxy-acid dehydratase
T2812B_01930	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
T2812B_01940	ENOG4105C7K	acetolactate synthase
T2812B_01945	ENOG4105CFH	Aspartokinase
T2812B_01950	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
T2812B_01955	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
T2812B_01960	ENOG4105CJ1	ABC, transporter
T2812B_01975	ENOG4107GFK	fumarate
T2812B_01985	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
T2812B_01990	ENOG4105PGM	cation diffusion facilitator family transporter
T2812B_01995	ENOG4106D4I	domain protein
T2812B_02010	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
T2812B_02015	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
T2812B_02030	ENOG4108JQ7	(ABC) transporter
T2812B_02035	ENOG410681U	heavy metal transport detoxification protein
T2812B_02040	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
T2812B_02045	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
T2812B_02050	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
T2812B_02055	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
T2812B_02075	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
T2812B_02080	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
T2812B_02085	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
T2812B_02120	ENOG4105N5T	Radical SAM Protein
T2812B_02125	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
T2812B_02130	ENOG4105C0P	Mg chelatase subunit ChlI
T2812B_02140	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
T2812B_02155	ENOG4105D1H	recombination factor protein RarA
T2812B_02160	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
T2812B_02165	ENOG41083C3	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
T2812B_02175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
T2812B_02185	ENOG4108JQ7	(ABC) transporter
T2812B_02205	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
T2812B_02210	ENOG4108IAB	Phoh family
T2812B_02215	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
T2812B_02220	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
T2812B_02225	ENOG4105C31	Tryptophanyl-tRNA synthetase
T2812B_02235	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
T2812B_02245	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
T2812B_02250	ENOG4105VG1	fes assembly suf system protein
T2812B_02260	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
T2812B_02265	ENOG4107XKF	NMT1 THI5 Like Domain Protein
T2812B_02270	ENOG4108IY8	ABC, transporter
T2812B_02285	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
T2812B_02295	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
T2812B_02300	ENOG4105QZY	s-layer domain protein
T2812B_02310	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
T2812B_02320	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
T2812B_02325	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
T2812B_02345	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
T2812B_02355	ENOG4105CDY	transcriptional regulatory protein
T2812B_02365	ENOG4105BZU	Histidine kinase
T2812B_02370	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
T2812B_02375	ENOG4105C34	Pseudouridine synthase
T2812B_02380	ENOG4105C0B	DNA polymerase III (alpha subunit)
T2812B_02385	ENOG4105DEF	Extracellular solute-binding protein, family 5
T2812B_02390	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
T2812B_02395	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
T2812B_02400	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
T2812B_02405	ENOG41081WB	50s ribosomal protein L10
T2812B_02410	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
T2812B_02415	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
T2812B_02420	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
T2812B_02425	ENOG410683Z	Preprotein translocase SecE subunit
T2812B_02430	ENOG41086IP	50S ribosomal protein L33
T2812B_02440	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
T2812B_02445	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
T2812B_02450	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
T2812B_02455	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
T2812B_02460	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
T2812B_02465	ENOG4108IJ0	Aspartate ammonia-lyase
T2812B_02470	ENOG4105CMG	Carbohydrate kinase
T2812B_02480	ENOG4105CHR	reductase
T2812B_02490	ENOG4108WYP	Transcriptional regulator
T2812B_02495	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
T2812B_02525	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
T2812B_02530	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
T2812B_02535	ENOG4105C3U	ABC transporter
T2812B_02540	ENOG4108JQ7	(ABC) transporter
T2812B_02545	ENOG4105DBA	pectate lyase
T2812B_02555	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
T2812B_02565	ENOG4105I82	acetyl xylan esterase
T2812B_02570	ENOG4107V4V	glycoside hydrolase family 4
T2812B_02575	ENOG4105DBA	pectate lyase
T2812B_02590	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
T2812B_02595	ENOG4105C8Q	Methyl-accepting chemotaxis
T2812B_02600	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
T2812B_02625	ENOG4105DCT	glycerol dehydrogenase
T2812B_02640	ENOG4105EG2	ABC transporter, permease
T2812B_02645	ENOG4105D56	permease protein
T2812B_02655	ENOG4107S8A	protein TIM barrel
T2812B_02665	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
T2812B_02670	ENOG4107W9I	Creatinine amidohydrolase
T2812B_02675	ENOG4105CPQ	Dehydrogenase
T2812B_02690	ENOG4105DR5	peptidase
T2812B_02695	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
T2812B_02710	ENOG4105DQU	oxidoreductase, subunit beta
T2812B_02720	ENOG4108YZA	Nitrogen regulatory protein pii
T2812B_02730	ENOG4107104	thymidine kinase
T2812B_02745	ENOG4105EYU	Glutamine amido-transferase
T2812B_02750	ENOG4105CBC	glutamate synthase
T2812B_02755	ENOG4105BZ8	glutamate synthase
T2812B_02775	ENOG41088YS	Glycosyl transferase (Group 1
T2812B_02780	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
T2812B_02785	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
T2812B_02800	ENOG4105CEN	a g-specific adenine glycosylase
T2812B_02805	ENOG4108TVJ	Nitroreductase
T2812B_02815	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
T2812B_02820	ENOG4108TVJ	Nitroreductase
T2812B_02835	ENOG4105CJ1	ABC, transporter
T2812B_02840	ENOG4105EJ9	Membrane
T2812B_02845	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
T2812B_02850	ENOG4105VN1	Heat shock protein
T2812B_02855	ENOG4105CFG	Acts as a chaperone (By similarity)
T2812B_02865	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
T2812B_02870	ENOG4105EHU	Circadian clock protein KaiC
T2812B_02890	ENOG4105CSM	endonuclease III
T2812B_02895	ENOG4105DFM	M18 family aminopeptidase
T2812B_02900	ENOG4105CG3	alpha amylase, catalytic region
T2812B_02905	ENOG4105F23	Fibronectin-binding protein
T2812B_02910	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
T2812B_02920	ENOG4105DXN	mazG family
T2812B_02930	ENOG4105CBD	Diacylglycerol kinase
T2812B_02945	ENOG4105C7B	Threonine dehydratase
T2812B_02960	ENOG410624X	efflux transporter, rnd family, mfp subunit
T2812B_02965	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
T2812B_02970	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
T2812B_02985	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
T2812B_02990	ENOG4105D49	3-dehydroquinate synthase
T2812B_03000	ENOG4108237	shikimate dehydrogenase
T2812B_03005	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
T2812B_03015	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
T2812B_03040	ENOG4105CCT	upf0313 protein
T2812B_03045	ENOG4105F6J	Alpha beta hydrolase fold
T2812B_03050	ENOG4107VJ5	dihydroorotase
T2812B_03055	ENOG4105I47	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
T2812B_03060	ENOG4107W93	Dihydroorotate dehydrogenase
T2812B_03065	ENOG4107YPM	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
T2812B_03070	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
T2812B_03075	ENOG4105EFZ	amidohydrolase
T2812B_03090	ENOG4108JQ1	Dehydrogenase
T2812B_03095	ENOG4106KNT	transcriptional regulator
T2812B_03100	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
T2812B_03105	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
T2812B_03115	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
T2812B_03135	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
T2812B_03140	ENOG4105C59	p-type ATPase
T2812B_03160	ENOG4105CPC	Aldo Keto reductase
T2812B_03165	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
T2812B_03185	ENOG4105CJQ	hydrolase, family 31
T2812B_03200	ENOG41061GT	Aldolase
T2812B_03205	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
T2812B_03210	ENOG4105CPQ	Dehydrogenase
T2812B_03215	ENOG4105CHR	reductase
T2812B_03240	ENOG4105CPQ	Dehydrogenase
T2812B_03245	ENOG4105ETE	Transcriptional regulator (LacI family
T2812B_03255	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
T2812B_03260	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
T2812B_03265	ENOG4105KRI	phosphocarrier protein (HPr
T2812B_03270	ENOG4105DM4	PTS System
T2812B_03275	ENOG4105DM4	PTS System
T2812B_03280	ENOG4105DE4	1-phosphofructokinase
T2812B_03285	ENOG4105E98	transcriptional regulator DeoR family
T2812B_03290	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
T2812B_03300	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
T2812B_03305	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
T2812B_03310	ENOG4105BZN	citrate synthase
T2812B_03315	ENOG4107UUY	ec 2.7.1.11
T2812B_03320	ENOG4105BZ1	(ABC) transporter
T2812B_03325	ENOG4105BZ1	(ABC) transporter
T2812B_03335	ENOG4108MDK	Dehydrogenase
T2812B_03340	ENOG4105CMG	Carbohydrate kinase
T2812B_03345	ENOG4105CR5	Class II aldolase adducin family protein
T2812B_03350	ENOG4105C2J	ABC transporter
T2812B_03355	ENOG4105CNN	ABC, transporter
T2812B_03360	ENOG4105D4B	ABC, transporter
T2812B_03365	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
T2812B_03370	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
T2812B_03385	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
T2812B_03390	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
T2812B_03405	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
T2812B_03420	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
T2812B_03430	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
T2812B_03435	ENOG4105D2N	Aldolase
T2812B_03440	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
T2812B_03460	ENOG4105C3R	Methionine synthase
T2812B_03465	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
T2812B_03470	ENOG4105K70	DNA-binding protein
T2812B_03475	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
T2812B_03480	ENOG4105I08	Pseudouridine synthase
T2812B_03485	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
T2812B_03490	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
T2812B_03495	ENOG4105CJ3	phosphate transporter
T2812B_03505	ENOG4105CPF	Cell wall formation (By similarity)
T2812B_03510	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
T2812B_03515	ENOG4105EQI	Metal Dependent Phosphohydrolase
T2812B_03525	ENOG4105VB9	50S ribosomal protein l28
T2812B_03530	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
T2812B_03535	ENOG41085R6	UPF0102 protein
T2812B_03540	ENOG41084A9	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
T2812B_03545	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
T2812B_03550	ENOG4105C79	DNA protecting protein DprA
T2812B_03555	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
T2812B_03565	ENOG4105DZB	Electron transport complex
T2812B_03575	ENOG4105D6A	Electron transport complex
T2812B_03580	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
T2812B_03585	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
T2812B_03600	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
T2812B_03605	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
T2812B_03615	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
T2812B_03620	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
T2812B_03625	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
T2812B_03635	ENOG4105CNI	cell division protein FtsW
T2812B_03660	ENOG4107QIZ	NADH dehydrogenase
T2812B_03665	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
T2812B_03675	ENOG4105K6H	D-cysteine desulfhydrase
T2812B_03680	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
T2812B_03690	ENOG4108JJB	ABC transporter
T2812B_03695	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
T2812B_03700	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
T2812B_03705	ENOG4105W2B	Flagellar assembly protein
T2812B_03720	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
T2812B_03725	ENOG4105KME	endoribonuclease L-psp
T2812B_03730	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
T2812B_03735	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
T2812B_03740	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
T2812B_03745	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
T2812B_03755	ENOG4105CTQ	phosphohexokinase
T2812B_03760	ENOG4105CA9	Pyruvate kinase
T2812B_03765	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
T2812B_03770	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
T2812B_03795	ENOG4107QHI	-hydrogenase
T2812B_03800	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
T2812B_03805	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
T2812B_03810	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
T2812B_03815	ENOG4107R56	PP-loop domain protein
T2812B_03825	ENOG4107R33	ppx gppa phosphatase
T2812B_03830	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
T2812B_03835	ENOG4105C4B	ABC transporter, permease
T2812B_03840	ENOG4105MCT	stage V sporulation protein S
T2812B_03845	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
T2812B_03850	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
T2812B_03855	ENOG4105S10	periplasmic binding protein
T2812B_03865	ENOG4105BZU	Histidine kinase
T2812B_03870	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
T2812B_03880	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
T2812B_03885	ENOG4105C4K	Nad synthetase
T2812B_03890	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
T2812B_03910	ENOG4105C25	Primosomal protein n'
T2812B_03925	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
T2812B_03930	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
T2812B_03935	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
T2812B_03940	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
T2812B_03945	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
T2812B_03955	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
T2812B_03960	ENOG4105C8T	Leucyl-tRNA synthetase
T2812B_03965	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
T2812B_03970	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
T2812B_03975	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
T2812B_03995	ENOG4105CTB	Polyprenyl synthetase
T2812B_04005	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
T2812B_04010	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
T2812B_04025	ENOG4105G6Z	alkaline phosphatase
T2812B_04030	ENOG4105CQC	Prephenate dehydratase
T2812B_04050	ENOG41085U1	50S ribosomal protein L32
T2812B_04055	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
T2812B_04060	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
T2812B_04065	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
T2812B_04070	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
T2812B_04075	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
T2812B_04085	ENOG4105BZU	Histidine kinase
T2812B_04090	ENOG4105CRQ	synthase (Component I)
T2812B_04095	ENOG4105DDQ	anthranilate synthase
T2812B_04100	ENOG4105DK0	Indole-3-glycerol phosphate synthase
T2812B_04105	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
T2812B_04110	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
T2812B_04115	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
T2812B_04120	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
T2812B_04130	ENOG4105C3M	thioredoxin reductase
T2812B_04135	ENOG4108W2Y	isochorismatase
T2812B_04140	ENOG4105I03	Flagellin
T2812B_04155	ENOG4107QSA	Oxaloacetate decarboxylase
T2812B_04165	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
T2812B_04170	ENOG41080V6	ABC-3 protein
T2812B_04175	ENOG4105FDK	ABC transporter
T2812B_04180	ENOG4107XSR	periplasmic solute binding protein
T2812B_04190	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
T2812B_04195	ENOG4108TVJ	Nitroreductase
T2812B_04215	ENOG4105CMG	Carbohydrate kinase
T2812B_04220	ENOG4105C2J	ABC transporter
T2812B_04235	ENOG4105CNN	ABC, transporter
T2812B_04245	ENOG4105E2R	ROK family
T2812B_04255	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
T2812B_04275	ENOG4105UIB	(ABC) transporter
T2812B_04280	ENOG4108JQ9	ABC transporter
T2812B_04285	ENOG4105DIH	basic membrane
T2812B_04295	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
T2812B_04305	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
T2812B_04310	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
T2812B_04315	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
T2812B_04320	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
T2812B_04325	ENOG4105D7Q	type ii secretion system
T2812B_04360	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
T2812B_04365	ENOG4105CJR	Integral membrane protein (MviN
T2812B_04385	ENOG4105DTJ	flagellar hook-associated protein
T2812B_04390	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
T2812B_04395	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
T2812B_04400	ENOG4105EHG	Permease protein
T2812B_04405	ENOG4105E0A	ABC, transporter
T2812B_04410	ENOG4105I82	acetyl xylan esterase
T2812B_04415	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
T2812B_04430	ENOG4105C3U	ABC transporter
T2812B_04435	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
T2812B_04440	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
T2812B_04450	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
T2812B_04455	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
T2812B_04460	ENOG4105DEI	Mannitol dehydrogenase
T2812B_04470	ENOG4108UHU	Aldolase
T2812B_04475	ENOG4107258	Transcriptional regulator
T2812B_04480	ENOG4105D2H	Uronic isomerase
T2812B_04495	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
T2812B_04500	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
T2812B_04505	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
T2812B_04510	ENOG4105C3U	ABC transporter
T2812B_04515	ENOG4108JQ7	(ABC) transporter
T2812B_04525	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
T2812B_04545	ENOG4105CE1	Ferrous iron transport protein b
T2812B_04570	ENOG4105BZ1	(ABC) transporter
T2812B_04575	ENOG4105DC7	peptidase M24
T2812B_04580	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
T2812B_04590	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
T2812B_04595	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
T2812B_04600	ENOG4105CPI	Metal Dependent Phosphohydrolase
T2812B_04605	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
T2812B_04630	ENOG4108J59	Extracellular solute-binding protein, family 5
T2812B_04650	ENOG4108JQ7	(ABC) transporter
T2812B_04660	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
T2812B_04670	ENOG4105C8Q	Methyl-accepting chemotaxis
T2812B_04675	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
T2812B_04680	ENOG4105KJJ	Uncharacterized ACR, COG1993
T2812B_04685	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
T2812B_04690	ENOG4105DDK	oxidoreductase, beta subunit
T2812B_04695	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
T2812B_04700	ENOG4105WGB	oxidoreductase, delta subunit
T2812B_04705	ENOG4105EJ5	oxidoreductase gamma subunit
T2812B_04710	ENOG4105C8Q	Methyl-accepting chemotaxis
T2812B_04720	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
T2812B_04730	ENOG4107QIZ	NADH dehydrogenase
T2812B_04750	ENOG4105DTQ	mandelate racemase muconate lactonizing
T2812B_04765	ENOG4105CGH	5'-nucleotidase
T2812B_04775	ENOG4108RE9	Phosphodiesterase
T2812B_04785	ENOG4105VEQ	Cold shock protein
T2812B_04795	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
T2812B_04805	ENOG4107U53	septum site-determining protein minD
T2812B_04810	ENOG4105DAN	ATP-dependent protease
T2812B_04815	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
T2812B_04830	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
T2812B_04855	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
T2812B_04860	ENOG41081HM	2'-5' rna ligase
T2812B_04870	ENOG4108489	Modulates RecA activity (By similarity)
T2812B_04875	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
T2812B_04890	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
T2812B_04895	ENOG4105DRS	transport system, permease
T2812B_04920	ENOG4105E2V	Glycosyltransferase 36
T2812B_04930	ENOG4107T3P	ABC, transporter
T2812B_04945	ENOG4105E2R	ROK family
T2812B_04955	ENOG4108IUM	Glycogen debranching enzyme
T2812B_04975	ENOG4107FKK	extracellular solute-binding protein family 1
T2812B_04980	ENOG4105D56	permease protein
T2812B_04985	ENOG4105EG2	ABC transporter, permease
T2812B_04990	ENOG4108IUK	alpha amylase, catalytic
T2812B_04995	ENOG4107V4V	glycoside hydrolase family 4
T2812B_05000	ENOG4108T5G	Adenylate
T2812B_05015	ENOG4105BZU	Histidine kinase
T2812B_05020	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
T2812B_05025	ENOG4108R6K	riboflavin synthase, subunit alpha
T2812B_05030	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
T2812B_05035	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
T2812B_05045	ENOG4105EPW	hflc protein
T2812B_05050	ENOG4107QJR	hflk protein
T2812B_05055	ENOG4105GRF	N-glycosylase DNA lyase
T2812B_05060	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
T2812B_05070	ENOG4105FGV	Chromate
T2812B_05075	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
T2812B_05100	ENOG410695F	Crispr-associated protein, Csm1 family
T2812B_05110	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
T2812B_05120	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
T2812B_05145	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
T2812B_05180	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
T2812B_05185	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
T2812B_05230	ENOG4105BZU	Histidine kinase
T2812B_05250	ENOG4105C8Y	Acetylornithine aminotransferase
T2812B_05255	ENOG4105CAS	nag kinase
T2812B_05260	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
T2812B_05265	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
T2812B_05270	ENOG4105CH7	arginosuccinase
T2812B_05275	ENOG4105CDH	Citrulline--aspartate ligase
T2812B_05285	ENOG4105CHV	Transcription elongation factor NusA
T2812B_05290	ENOG4105I3K	Ferric uptake regulator, Fur family
T2812B_05300	ENOG4105E3H	phosphoglycerate mutase
T2812B_05320	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
T2812B_05330	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
T2812B_05335	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
T2812B_05340	ENOG4105CKU	formyltetrahydrofolate synthetase
T2812B_05345	ENOG4105M7K	Involved in the transcription termination process (By similarity)
T2812B_05355	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
T2812B_05360	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
T2812B_05365	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
T2812B_05395	ENOG4105CKM	Branched-chain carboxylic acid kinase
T2812B_05400	ENOG4107RE7	phosphate butyryltransferase
T2812B_05405	ENOG4105CKM	Branched-chain carboxylic acid kinase
T2812B_05415	ENOG4105C5W	Aldolase
T2812B_05430	ENOG4105CPC	Aldo Keto reductase
T2812B_05435	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
T2812B_05440	ENOG4105C2N	RNA methyltransferase TrmH family group 3
T2812B_05445	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
T2812B_05460	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
T2812B_05465	ENOG4105CDU	Replicative dna helicase
T2812B_05475	ENOG4105QGT	Phosphate uptake regulator
T2812B_05480	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
T2812B_05490	ENOG4105DFA	alanine racemase domain protein
T2812B_05495	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
T2812B_05520	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
T2812B_05530	ENOG4105CHR	reductase
T2812B_05535	ENOG4105CD3	dihydroorotase
T2812B_05550	ENOG41082BV	acetyltransferase
T2812B_05555	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
T2812B_05560	ENOG4105DJV	ribulose-phosphate 3-epimerase
T2812B_05565	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
T2812B_05575	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
T2812B_05585	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
T2812B_05605	ENOG4105CHW	UPF0052 protein
T2812B_05610	ENOG4105CIE	May be required for sporulation (By similarity)
T2812B_05615	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
T2812B_05620	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
T2812B_05625	ENOG4105CRK	lysyL-tRNA synthetase
T2812B_05635	ENOG4105E0M	Sulfatase
T2812B_05645	ENOG4107QJQ	Mate efflux family protein
T2812B_05665	ENOG4105CHM	Aminotransferase
T2812B_05685	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
T2812B_05710	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
T2812B_05715	ENOG41065EC	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
T2812B_05720	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
T2812B_05725	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
T2812B_05730	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
T2812B_05740	ENOG4105VEQ	Cold shock protein
T2812B_05770	ENOG4105CPI	Metal Dependent Phosphohydrolase
T2812B_05790	ENOG4105D00	flagellar biosynthetic protein flhB
T2812B_05810	ENOG4105C93	Xylose Isomerase
T2812B_05815	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
T2812B_05825	ENOG4107Y49	methyltransferase
T2812B_05830	ENOG4108JJB	ABC transporter
T2812B_05855	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
T2812B_05860	ENOG410857I	Binds directly to 16S ribosomal RNA (By similarity)
T2812B_05870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
T2812B_05875	ENOG4105BZU	Histidine kinase
T2812B_05890	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
T2812B_05905	ENOG4108WF2	Metal Dependent Phosphohydrolase
T2812B_05920	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
T2812B_05925	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
T2812B_05930	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
T2812B_05970	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
T2812B_05985	ENOG4105BZJ	Electron transfer flavoprotein
T2812B_05990	ENOG4105C10	Electron transfer flavoprotein
T2812B_05995	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
T2812B_06000	ENOG41090P5	ferredoxin-like protein
T2812B_06020	ENOG4105EPH	radical SAM domain protein
T2812B_06030	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
T2812B_06035	ENOG4105TZT	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
T2812B_06045	ENOG4105CGA	flagellar basal-body rod protein FlgG
T2812B_06050	ENOG4105KTQ	flagellar basal-body rod protein
T2812B_06060	ENOG41084RN	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
T2812B_06065	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
T2812B_06070	ENOG4105DCI	Phosphohydrolase
T2812B_06080	ENOG4107UKG	Glycosyl transferase, family 4
T2812B_06085	ENOG4105CBJ	Metal-dependent enzyme
T2812B_06090	ENOG4105NBF	ammecr1 domain protein
T2812B_06100	ENOG4105CJ2	(LipO)protein
T2812B_06115	ENOG4108Z03	MAF-like protein
T2812B_06120	ENOG4105W5Q	DNA repair protein (RadC
T2812B_06130	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
T2812B_06155	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
T2812B_06160	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
T2812B_06165	ENOG4105K5M	30s ribosomal protein S16
T2812B_06170	ENOG41084QK	UPF0109 protein
T2812B_06175	ENOG410836E	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
T2812B_06180	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
T2812B_06185	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
T2812B_06190	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
T2812B_06195	ENOG4105C3F	Signal peptidase i
T2812B_06215	ENOG4105DX0	Hemolysin A
T2812B_06225	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
T2812B_06230	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
T2812B_06235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
T2812B_06255	ENOG4105MJ2	Competence protein
T2812B_06260	ENOG4105D1Z	hydroxypyruvate reductase
T2812B_06275	ENOG4105BZU	Histidine kinase
T2812B_06285	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
T2812B_06290	ENOG41085B1	50s ribosomal protein L35
T2812B_06295	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
T2812B_06300	ENOG4105D1F	ATP-binding protein
T2812B_06305	ENOG4105BZU	Histidine kinase
T2812B_06310	ENOG4105SFS	phosphoesterase RecJ domain protein
T2812B_06315	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
T2812B_06320	ENOG4106M28	alanine racemase domain protein
T2812B_06325	ENOG4105EMN	RNA polymerase sigma factor
T2812B_06340	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
T2812B_06345	ENOG4108Z3G	3H domain protein
T2812B_06350	ENOG41079KZ	Major Facilitator Superfamily
T2812B_06355	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
T2812B_06360	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
T2812B_06365	ENOG4105C03	ribonuclease
T2812B_06370	ENOG4105MS2	ribosomal subunit Interface protein
T2812B_06375	ENOG4105EPR	degv family
T2812B_06380	ENOG41082J0	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
T2812B_06385	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
T2812B_06390	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
T2812B_06395	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
T2812B_06400	ENOG41085KK	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
T2812B_06405	ENOG41084Y9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
T2812B_06410	ENOG410855G	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
T2812B_06415	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
T2812B_06430	ENOG4108W5Z	CheC domain protein
T2812B_06435	ENOG4105C2M	dna polymerase I
T2812B_06445	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
T2812B_06455	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
T2812B_06460	ENOG4105CNT	hydrolase family 2
T2812B_06475	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
T2812B_06480	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
T2812B_06485	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
T2812B_06500	ENOG4105K8N	protein family UPF0079, ATPase
T2812B_06505	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
T2812B_06515	ENOG4107RH8	nuclease SbcCD subunit D
T2812B_06520	ENOG4107WZZ	SMC domain protein
T2812B_06530	ENOG4105CJ1	ABC, transporter
T2812B_06535	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
T2812B_06540	ENOG4105BZ8	glutamate synthase
T2812B_06545	ENOG41084X0	Dihydrofolate reductase
T2812B_06550	ENOG4105CXT	aspartate transcarbamylase
T2812B_06565	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
T2812B_06570	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
T2812B_06575	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
T2812B_06580	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
T2812B_06585	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
T2812B_06595	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
T2812B_06600	ENOG4105CH2	amidohydrolase
T2812B_06615	ENOG4105CDE	UPF0348 protein
T2812B_06620	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
T2812B_06635	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
T2812B_06640	ENOG4105CTJ	Metal Dependent Phosphohydrolase
T2812B_06645	ENOG4105C9A	Phoh family
T2812B_06655	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
T2812B_06660	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
T2812B_06665	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
T2812B_06670	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
T2812B_06675	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
T2812B_06680	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
T2812B_06685	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
T2812B_06690	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
T2812B_06695	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
T2812B_06700	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
T2812B_06705	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
T2812B_06710	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
T2812B_06715	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
T2812B_06720	ENOG41084ME	50s ribosomal protein l29
T2812B_06725	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
T2812B_06730	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
T2812B_06735	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
T2812B_06745	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
T2812B_06750	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
T2812B_06755	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
T2812B_06760	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
T2812B_06765	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
T2812B_06770	ENOG4105VPB	50S ribosomal protein L30
T2812B_06775	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
T2812B_06780	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
T2812B_06785	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
T2812B_06795	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
T2812B_06800	ENOG41086MH	50S ribosomal protein L36
T2812B_06805	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
T2812B_06810	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
T2812B_06815	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
T2812B_06820	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
T2812B_06825	ENOG4108ZT0	50S ribosomal protein l17
T2812B_06830	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
T2812B_06835	ENOG4105DKQ	ROK family
T2812B_06840	ENOG4105EPR	degv family
T2812B_06850	ENOG4105DHT	Metal Dependent Phosphohydrolase
T2812B_06860	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
T2812B_06870	ENOG41085QA	50S ribosomal protein l34
T2812B_06880	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
T2812B_06885	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
T2812B_06910	ENOG4105K46	50S ribosomal protein l27
T2812B_06915	ENOG41081BK	membrane protein-like protein
T2812B_06920	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
T2812B_06925	ENOG4108UJD	30S ribosomal protein S9
T2812B_06930	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
T2812B_06935	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
T2812B_06940	ENOG4108JA2	transcriptioN-repair coupling factor
T2812B_06955	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
T2812B_06960	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
T2812B_06965	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
T2812B_06970	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
T2812B_06975	ENOG4107RB4	Cytidine monophosphate kinase
T2812B_06980	ENOG41084GC	stage II sporulation protein
T2812B_06985	ENOG4105C9M	aspartyl-trna synthetase
T2812B_06990	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
T2812B_07000	ENOG4107RFW	hydrolase family 57
T2812B_07005	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
T2812B_07030	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
T2812B_07035	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
T2812B_07040	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
T2812B_07045	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
T2812B_07050	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
T2812B_07055	ENOG4107QHI	-hydrogenase
T2812B_07060	ENOG4107QIZ	NADH dehydrogenase
T2812B_07065	ENOG4105GKE	subunit e
T2812B_07080	ENOG4105Y5S	NADH ubiquinone oxidoreductase, 24 kD
T2812B_07095	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
T2812B_07100	ENOG4105C3K	feS assembly ATPase SufC
T2812B_07105	ENOG4105DIW	FeS assembly protein SUFB
T2812B_07110	ENOG4105ECY	inositol monophosphatase
T2812B_07115	ENOG4108HKT	sucrose-6-phosphate hydrolase
T2812B_07140	ENOG4108JQ1	Dehydrogenase
T2812B_07145	ENOG4105C5R	Aminotransferase
T2812B_07150	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
T2812B_07155	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
T2812B_07160	ENOG4105KNE	Phosphatidate cytidylyltransferase
T2812B_07165	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
T2812B_07175	ENOG4107S82	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
T2812B_07180	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
T2812B_07185	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
T2812B_07195	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
T2812B_07200	ENOG4106H78	methyltransferase
T2812B_07205	ENOG41083IT	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
T2812B_07215	ENOG4105C89	phosphohexose isomerase
T2812B_07220	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
T2812B_07240	ENOG4108TSD	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
T2812B_07245	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
T2812B_07250	ENOG4105D38	putrescine abc transporter
T2812B_07255	ENOG4105F38	ABC transporter, permease
T2812B_07260	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
T2812B_07265	ENOG4107RUE	extracellular solute-binding protein family 1
T2812B_07270	ENOG4105CVJ	phosphoglycerate mutase
T2812B_07280	ENOG4107YH3	SUF system FeS assembly protein, NifU family
T2812B_07285	ENOG4105C9B	Cysteine desulfurase
T2812B_07295	ENOG4105DIW	FeS assembly protein SUFB
T2812B_07300	ENOG4105C3K	feS assembly ATPase SufC
T2812B_07310	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
T2812B_07315	ENOG4108ZC9	flagellar basal-body rod protein flgc
T2812B_07320	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
T2812B_07325	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
T2812B_07330	ENOG4105CZX	twitching motility protein
T2812B_07335	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
T2812B_07340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
T2812B_07345	ENOG4105BZU	Histidine kinase
T2812B_07370	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
T2812B_07385	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
T2812B_07390	ENOG4105E5G	Alpha beta hydrolase fold
T2812B_07395	ENOG4107Z0G	Domain of unknown function DUF20
T2812B_07405	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
T2812B_07410	ENOG4105C1V	Peptidase, M16
T2812B_07415	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
T2812B_07420	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
T2812B_07445	ENOG4108FN7	Aldo keto reductase
T2812B_07460	ENOG4105DRS	transport system, permease
T2812B_07485	ENOG4105BZ1	(ABC) transporter
T2812B_07495	ENOG4108IUW	ABC transporter
T2812B_07530	ENOG4106HX1	Uncharacterised protein family (UPF0150)
T2812B_07550	ENOG4105BZ1	(ABC) transporter
T2812B_07580	ENOG4108IUW	ABC transporter
T2812B_07595	ENOG4108FN7	Aldo keto reductase
T2812B_07610	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
T2812B_07625	ENOG4105W06	Cupin 2, conserved barrel domain protein
T2812B_07630	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
T2812B_07635	ENOG4105F8D	glycoside hydrolase family 4
T2812B_07650	ENOG4105C98	muts2 protein
T2812B_07655	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
T2812B_07675	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
T2812B_07680	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
T2812B_07690	ENOG4105C28	cystathionine
T2812B_07695	ENOG4107QW8	radical SAM domain protein
T2812B_07720	ENOG4105CVA	phosphate
T2812B_07735	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
T2812B_07740	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
T2812B_07745	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
T2812B_07760	ENOG4105BZ1	(ABC) transporter
T2812B_07765	ENOG4105CHM	Aminotransferase
T2812B_07770	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
T2812B_07775	ENOG4105C4K	Nad synthetase
T2812B_07785	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
T2812B_07790	ENOG4107QNG	Phosphoribosylglycinamide synthetase
T2812B_07795	ENOG4105DC1	bifunctional purine biosynthesis protein purh
T2812B_07800	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
T2812B_07810	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
T2812B_07815	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
T2812B_07820	ENOG4108A1T	Phosphoribosylformylglycinamidine synthase, purS
T2812B_07825	ENOG4105C8V	SAICAR synthetase
T2812B_07835	ENOG4105C3G	gtp-binding protein
T2812B_07845	ENOG4105C4R	Atp-dependent dna helicase
T2812B_07870	ENOG4108IJ9	(ABC) transporter
T2812B_07880	ENOG4105IRK	Glycosyl transferase (Group 1
T2812B_07885	ENOG4106J7S	Glycosyl transferase, family 2
T2812B_07900	ENOG4107QRA	Extracellular solute-binding protein, family 5
T2812B_07905	ENOG4105CKB	glycosidase
T2812B_07910	ENOG4105E2R	ROK family
T2812B_07915	ENOG4108J59	Extracellular solute-binding protein, family 5
T2812B_07920	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
T2812B_07925	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
T2812B_07935	ENOG4108JQ7	(ABC) transporter
T2812B_07940	ENOG4105ETE	Transcriptional regulator (LacI family
T2812B_07950	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
T2812B_07955	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
T2812B_07960	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
T2812B_07970	ENOG4108JPZ	Monovalent cation H antiporter subunit D
T2812B_07975	ENOG4108JPZ	Monovalent cation H antiporter subunit D
T2812B_07985	ENOG4105D65	subunit l
T2812B_08000	ENOG410684G	monovalent cation H antiporter subunit F
T2812B_08005	ENOG4105SC1	monovalent cation H antiporter subunit E
T2812B_08010	ENOG4107FKK	extracellular solute-binding protein family 1
T2812B_08015	ENOG4105D56	permease protein
T2812B_08020	ENOG4105EG2	ABC transporter, permease
T2812B_08030	ENOG4105ETE	Transcriptional regulator (LacI family
T2812B_08040	ENOG4105CNT	hydrolase family 2
T2812B_08045	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
T2812B_08050	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
T2812B_08055	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
T2812B_08070	ENOG4108KHP	Diguanylate cyclase
T2812B_08080	ENOG4107WSY	Domain of unknown function DUF20
T2812B_08090	ENOG4108Z5K	methylglyoxal synthase
T2812B_08095	ENOG4105BZU	Histidine kinase
T2812B_08100	ENOG4107SET	aldo keto reductase
T2812B_08105	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
T2812B_08110	ENOG4108YZ4	nudix hydrolase
T2812B_08120	ENOG4105MQ3	flagellar protein FliS
T2812B_08125	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
T2812B_08135	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
T2812B_08145	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
T2812B_08150	ENOG4105CHR	reductase
T2812B_08155	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
T2812B_08165	ENOG4105CSA	Coproporphyrinogen iii oxidase
T2812B_08170	ENOG4105DQU	oxidoreductase, subunit beta
T2812B_08180	ENOG4108KHP	Diguanylate cyclase
T2812B_08190	ENOG4105CJW	magnesium transporter
T2812B_08220	ENOG41067S9	phage shock protein C, PspC
T2812B_08225	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
T2812B_08230	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
T2812B_08235	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
T2812B_08245	ENOG4108JQ7	(ABC) transporter
T2812B_08250	ENOG4105DEF	Extracellular solute-binding protein, family 5
T2812B_08255	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
T2812B_08265	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
T2812B_08285	ENOG4107QIV	Cytochrome c biogenesis protein
T2812B_08290	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
T2812B_08295	ENOG4108IV0	ABC, transporter
T2812B_08300	ENOG4105C0Z	ABC transporter
T2812B_08305	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
T2812B_08310	ENOG4105C32	Amino acid ABC transporter (Permease)
T2812B_08335	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
T2812B_08340	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
T2812B_08345	ENOG4107RE7	phosphate butyryltransferase
T2812B_08350	ENOG41083B7	nucleosidase (EC 3.2.2.9)
T2812B_08385	ENOG4107V1F	Flagellar hook-associated 2 domain-containing protein
T2812B_08460	ENOG4108JPZ	Monovalent cation H antiporter subunit D
T2812B_08475	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
T2812B_08480	ENOG4108RE9	Phosphodiesterase
T2812B_08490	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
T2812B_08500	ENOG4105DBV	ornithine carbamoyltransferase
T2812B_08505	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
T2812B_08510	ENOG4105C83	adenylosuccinate lyase
T2812B_08515	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
T2812B_08520	ENOG4105C75	arginyL-tRNA synthetase
T2812B_08540	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
T2812B_08550	ENOG4107VEG	TrkA-N domain protein
T2812B_08565	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
T2812B_08570	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
T2812B_08575	ENOG4106FU4	Archease protein family (MTH1598/TM1083)
T2812B_08580	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
T2812B_08585	ENOG410682B	stage II sporulation protein
T2812B_08590	ENOG4108YZG	isomerase
T2812B_08595	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
T2812B_08605	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
T2812B_08625	ENOG4105DET	Rhamnulokinase
T2812B_08635	ENOG4105C9F	isomerase
T2812B_08645	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
T2812B_08650	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
T2812B_08655	ENOG4105C3U	ABC transporter
T2812B_08660	ENOG4108JQ7	(ABC) transporter
T2812B_08710	ENOG4105CNT	hydrolase family 2
T2812B_08725	ENOG4105MVE	transcriptional regulator
T2812B_08735	ENOG4105CNT	hydrolase family 2
T2812B_08745	ENOG4105MCT	stage V sporulation protein S
T2812B_08755	ENOG4107SVH	Potassium channel protein
T2812B_08760	ENOG4108531	cuta1 divalent ion tolerance protein
T2812B_08770	ENOG4108IUZ	ABC transporter
T2812B_08780	ENOG4105KQC	Competence protein
T2812B_08790	ENOG4105CN9	Peptidase m42 family protein
T2812B_08795	ENOG4105CN9	Peptidase m42 family protein
T2812B_08800	ENOG4105CN9	Peptidase m42 family protein
T2812B_08805	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
T2812B_08825	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
T2812B_08830	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
T2812B_08840	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
T2812B_08845	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
T2812B_08850	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
T2812B_08855	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
T2812B_08860	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
T2812B_08865	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
T2812B_08870	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
T2812B_08895	ENOG4105CIG	ABC transporter
T2812B_08935	ENOG4107RCC	Major Facilitator Superfamily
T2812B_08960	ENOG4105D82	Glutamate dehydrogenase
T2812B_08985	ENOG4105CF7	AraC family transcriptional regulator
T2812B_09010	ENOG4108QJJ	Protein of unknown function (DUF1175)
T2812B_09020	ENOG4107S85	alpha-2-macroglobulin domain protein
T2812B_09025	ENOG41084XP	SirA-like domain-containing protein
T2812B_09030	ENOG4105CUC	YeeE YedE family protein
T2812B_09050	ENOG41084XP	SirA-like domain-containing protein
T2812B_09055	ENOG4105DHT	Metal Dependent Phosphohydrolase
T2812B_09060	ENOG4105C8Q	Methyl-accepting chemotaxis
T2812B_09065	ENOG4105BZU	Histidine kinase
T2812B_09085	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
T2812B_09095	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
T2812B_09100	ENOG4108086	Protein of unknown function DUF111
T2812B_09115	ENOG4108V0P	LemA family
T2812B_09120	ENOG4108RVA	ribokinase
T2812B_09125	ENOG4108HHA	Transketolase
T2812B_09130	ENOG4108IUS	Transketolase
T2812B_09135	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
T2812B_09205	ENOG4105C5F	glutamine synthetase
T2812B_09220	ENOG4105EI2	Pseudouridine synthase
T2812B_09225	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
T2812B_09240	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
T2812B_09245	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
T2812B_09250	ENOG4107R3E	Citrate transporter
T2812B_09275	ENOG4105EZM	VWA-like domain (DUF2201)
T2812B_09280	ENOG41063SX	
T2812B_09285	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein