locus-tag	class	description
CELL2_00010	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CELL2_00025	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CELL2_00030	ENOG4105E4C	Lytic transglycosylase catalytic
CELL2_00045	ENOG4105C8Q	Methyl-accepting chemotaxis
CELL2_00065	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CELL2_00070	ENOG41080JC	Protein of unknown function DUF47
CELL2_00090	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CELL2_00095	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CELL2_00100	ENOG4105D00	flagellar biosynthetic protein flhB
CELL2_00105	ENOG4105D7B	Flagellar biosynthesis protein flha
CELL2_00110	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CELL2_00125	ENOG4107PHP	CheC --inhibitor of MCP methylation
CELL2_00130	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
CELL2_00135	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CELL2_00165	ENOG4105MCT	stage V sporulation protein S
CELL2_00170	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
CELL2_00175	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CELL2_00185	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CELL2_00190	ENOG4105CJW	magnesium transporter
CELL2_00195	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CELL2_00200	ENOG4105DZP	Membrane-associated zinc metalloprotease
CELL2_00205	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CELL2_00215	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CELL2_00220	ENOG4108JQC	penicillin-binding protein 1A
CELL2_00245	ENOG4105CVG	Homoserine O-transsuccinylase
CELL2_00250	ENOG4105D9Q	decarboxylase (Beta subunit)
CELL2_00260	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
CELL2_00265	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CELL2_00285	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CELL2_00290	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CELL2_00310	ENOG4105C3M	thioredoxin reductase
CELL2_00315	ENOG4108JU3	Alkyl hydroperoxide reductase
CELL2_00335	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CELL2_00350	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
CELL2_00355	ENOG4107VRQ	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CELL2_00360	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CELL2_00365	ENOG4107Z7W	Preprotein translocase YajC subunit
CELL2_00380	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CELL2_00385	ENOG41084NJ	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CELL2_00390	ENOG4108HU6	Metal dependent phosphohydrolase
CELL2_00395	ENOG4105BZU	Histidine kinase
CELL2_00425	ENOG4105CQW	ribosome biogenesis GTPase YqeH
CELL2_00430	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CELL2_00435	ENOG4105KG3	cytidine deaminase
CELL2_00440	ENOG4108JU5	Magnesium and cobalt efflux protein
CELL2_00445	ENOG41082VF	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CELL2_00450	ENOG4105CCS	Glutamate formiminotransferase
CELL2_00455	ENOG4107YTP	response regulator receiver protein
CELL2_00470	ENOG4105CNI	cell division protein FtsW
CELL2_00480	ENOG4107QHF	type ii secretion system protein e
CELL2_00485	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CELL2_00490	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CELL2_00500	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CELL2_00510	ENOG4107Z5F	Aminotransferase class IV
CELL2_00515	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CELL2_00525	ENOG4105DE4	1-phosphofructokinase
CELL2_00530	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CELL2_00550	ENOG4108IG5	Transcriptional regulator
CELL2_00555	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CELL2_00560	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CELL2_00565	ENOG4107QW4	alcohol dehydrogenase
CELL2_00575	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
CELL2_00595	ENOG4105UQX	Mate efflux family protein
CELL2_00600	ENOG4105CE4	GlcNAc 6-P deacetylase
CELL2_00605	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CELL2_00610	ENOG4105DRS	transport system, permease
CELL2_00625	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CELL2_00630	ENOG4105E2R	ROK family
CELL2_00635	ENOG4105D3R	alkyl hydroperoxide reductase
CELL2_00645	ENOG4105ESV	Glycosyl transferase, family 4
CELL2_00650	ENOG4107RU2	Histidinol phosphate phosphatase, HisJ family
CELL2_00655	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CELL2_00660	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CELL2_00665	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CELL2_00670	ENOG4105EA8	2-Nitropropane dioxygenase
CELL2_00675	ENOG4105VKD	bioY protein
CELL2_00685	ENOG4108N5B	2-phosphosulfolactate phosphatase
CELL2_00710	ENOG4105CJ1	ABC, transporter
CELL2_00720	ENOG410816Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CELL2_00725	ENOG4107ZCS	Phosphomethylpyrimidine kinase
CELL2_00735	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CELL2_00740	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
CELL2_00750	ENOG41074CX	linocin_m18 bacteriocin protein
CELL2_00800	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CELL2_00810	ENOG41061AI	Protein of unknown function (DUF2905)
CELL2_00815	ENOG4105MA4	psp1 domain protein
CELL2_00820	ENOG4107QRG	dna polymerase iii
CELL2_00840	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CELL2_00845	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CELL2_00855	ENOG4105CJ1	ABC, transporter
CELL2_00865	ENOG4105K8R	UPF0145 protein
CELL2_00870	ENOG4105CE9	30S ribosomal protein S2
CELL2_00910	ENOG4105CNW	domain protein
CELL2_00915	ENOG4108IFG	nitrite reductase, (NAD(P)H)
CELL2_00920	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
CELL2_00925	ENOG4107V4V	glycoside hydrolase family 4
CELL2_00930	ENOG4105C22	threonyL-tRNA synthetase
CELL2_00945	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CELL2_00950	ENOG4105CN1	protease
CELL2_00965	ENOG4105BZF	Glycosyl transferase (Group 1
CELL2_00975	ENOG4107S1Q	Phosphatase
CELL2_00980	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CELL2_00990	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CELL2_01005	ENOG4105DG6	mannose-6-phosphate isomerase
CELL2_01030	ENOG4105WPN	DNA integration recombination invertion protein
CELL2_01040	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CELL2_01055	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CELL2_01060	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CELL2_01080	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CELL2_01085	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CELL2_01095	ENOG4105C8N	cysteinyl-tRNA synthetase
CELL2_01100	ENOG4105YFD	chemotaxis, protein
CELL2_01105	ENOG4107QSA	Oxaloacetate decarboxylase
CELL2_01115	ENOG4105D8K	carboxyl transferase
CELL2_01150	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CELL2_01155	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
CELL2_01160	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CELL2_01170	ENOG4105C19	ABC transporter
CELL2_01175	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CELL2_01180	ENOG4105CEV	competence damage-inducible protein
CELL2_01185	ENOG4105CBS	Chea signal transduction histidine kinase
CELL2_01190	ENOG4105YVF	chew protein
CELL2_01195	ENOG4107YTP	response regulator receiver protein
CELL2_01205	ENOG4105CN7	Flagellar biosynthetic protein FliP
CELL2_01220	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CELL2_01225	ENOG4107XYV	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
CELL2_01235	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CELL2_01250	ENOG4105BZA	Phosphoglycerate kinase
CELL2_01255	ENOG4105BZA	Phosphoglycerate kinase
CELL2_01260	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CELL2_01265	ENOG41085TI	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CELL2_01270	ENOG4105C6E	dna polymerase iii
CELL2_01325	ENOG4105ER2	Ompa motb domain protein
CELL2_01330	ENOG4105E14	MotA TolQ exbB proton channel
CELL2_01335	ENOG41068WV	flagellar FlbD family protein
CELL2_01340	ENOG4105BZE	flagellar hook protein, FlgE
CELL2_01375	ENOG4105F8V	Hydrolase, tatD family
CELL2_01380	ENOG4105D7W	serine acetyltransferase
CELL2_01385	ENOG4105C6T	cysteine synthase
CELL2_01400	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CELL2_01410	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
CELL2_01415	ENOG4105VCQ	rubredoxin
CELL2_01420	ENOG4108YZ8	Superoxide reductase
CELL2_01425	ENOG4108RAC	Rubrerythrin
CELL2_01430	ENOG4106A7E	Transcriptional regulator
CELL2_01435	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
CELL2_01440	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CELL2_01445	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CELL2_01455	ENOG410667J	hydrolase
CELL2_01470	ENOG41082Q0	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CELL2_01480	ENOG4107S7H	nh(3)-dependent nad( ) synthetase
CELL2_01515	ENOG4105DAY	polysaccharide export protein
CELL2_01540	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CELL2_01555	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CELL2_01590	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CELL2_01595	ENOG4107RA4	Glycosyl transferase (Group 1
CELL2_01625	ENOG4107RA4	Glycosyl transferase (Group 1
CELL2_01630	ENOG4108RJ9	Glycosyl transferase, family 2
CELL2_01685	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CELL2_01705	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CELL2_01715	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CELL2_01720	ENOG4108UUM	single-stranded DNA-binding protein
CELL2_01725	ENOG41083EQ	Binds together with S18 to 16S ribosomal RNA (By similarity)
CELL2_01755	ENOG4105DRS	transport system, permease
CELL2_01770	ENOG4105C7N	Xanthine uracil vitamin C permease
CELL2_01775	ENOG4105EAB	amino acid AbC transporter
CELL2_01780	ENOG4105E5Q	amino acid AbC transporter
CELL2_01790	ENOG4105CJN	penicillin-binding protein
CELL2_01805	ENOG4105DFF	Rod shape-determining protein mreb
CELL2_01810	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
CELL2_01815	ENOG410631K	Membrane
CELL2_01830	ENOG4107QQG	Dehydrogenase
CELL2_01845	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CELL2_01850	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CELL2_01855	ENOG4105II7	pyrroline-5-carboxylate reductase
CELL2_01860	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
CELL2_01865	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CELL2_01870	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CELL2_01875	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CELL2_01880	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CELL2_01885	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CELL2_01890	ENOG4105C0H	protease
CELL2_01895	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CELL2_01915	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
CELL2_01925	ENOG4107ZMQ	sugar fermentation stimulation protein
CELL2_01950	ENOG4105D7N	magnesium and cobalt transport protein CorA
CELL2_01970	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CELL2_01975	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CELL2_01980	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CELL2_01985	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CELL2_01990	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CELL2_01995	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CELL2_02000	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CELL2_02010	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CELL2_02020	ENOG4105C7K	acetolactate synthase
CELL2_02025	ENOG4105CFH	Aspartokinase
CELL2_02030	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
CELL2_02035	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CELL2_02040	ENOG4105CJ1	ABC, transporter
CELL2_02060	ENOG4107GFK	fumarate
CELL2_02070	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CELL2_02075	ENOG4105PGM	cation diffusion facilitator family transporter
CELL2_02080	ENOG4106D4I	domain protein
CELL2_02095	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CELL2_02100	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CELL2_02115	ENOG4108JQ7	(ABC) transporter
CELL2_02120	ENOG410681U	heavy metal transport detoxification protein
CELL2_02135	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CELL2_02140	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CELL2_02145	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CELL2_02170	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CELL2_02175	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CELL2_02200	ENOG4105N5T	Radical SAM Protein
CELL2_02205	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CELL2_02210	ENOG4105C0P	Mg chelatase subunit ChlI
CELL2_02220	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CELL2_02235	ENOG4105D1H	recombination factor protein RarA
CELL2_02240	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CELL2_02245	ENOG41083C3	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CELL2_02255	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CELL2_02270	ENOG4108JQ7	(ABC) transporter
CELL2_02290	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CELL2_02295	ENOG4108IAB	Phoh family
CELL2_02300	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CELL2_02305	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CELL2_02310	ENOG4105C31	Tryptophanyl-tRNA synthetase
CELL2_02320	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CELL2_02330	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CELL2_02335	ENOG4105VG1	fes assembly suf system protein
CELL2_02345	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CELL2_02350	ENOG4107XKF	NMT1 THI5 Like Domain Protein
CELL2_02355	ENOG4105D7T	ABC transporter
CELL2_02380	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CELL2_02390	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CELL2_02395	ENOG4105QZY	s-layer domain protein
CELL2_02400	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
CELL2_02410	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
CELL2_02435	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CELL2_02455	ENOG4105BZU	Histidine kinase
CELL2_02460	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CELL2_02465	ENOG4105C34	Pseudouridine synthase
CELL2_02470	ENOG4105C0B	DNA polymerase III (alpha subunit)
CELL2_02475	ENOG4108J59	Extracellular solute-binding protein, family 5
CELL2_02480	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CELL2_02485	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CELL2_02490	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CELL2_02495	ENOG41081WB	50s ribosomal protein L10
CELL2_02500	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CELL2_02505	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CELL2_02510	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CELL2_02515	ENOG410683Z	Preprotein translocase SecE subunit
CELL2_02520	ENOG41086IP	50S ribosomal protein L33
CELL2_02530	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
CELL2_02535	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CELL2_02550	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CELL2_02555	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CELL2_02560	ENOG4108IJ0	Aspartate ammonia-lyase
CELL2_02565	ENOG4105CMG	Carbohydrate kinase
CELL2_02590	ENOG4108WYP	Transcriptional regulator
CELL2_02595	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CELL2_02625	ENOG4105C2J	ABC transporter
CELL2_02630	ENOG4105CNN	ABC, transporter
CELL2_02640	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
CELL2_02650	ENOG4105EG2	ABC transporter, permease
CELL2_02655	ENOG4105D56	permease protein
CELL2_02665	ENOG4107S8A	protein TIM barrel
CELL2_02675	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CELL2_02680	ENOG4107W9I	Creatinine amidohydrolase
CELL2_02685	ENOG4105CPQ	Dehydrogenase
CELL2_02690	ENOG4105E2R	ROK family
CELL2_02700	ENOG4105DR5	peptidase
CELL2_02705	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CELL2_02720	ENOG4105DQU	oxidoreductase, subunit beta
CELL2_02730	ENOG4108YZA	Nitrogen regulatory protein pii
CELL2_02740	ENOG4107104	thymidine kinase
CELL2_02745	ENOG41062D9	Histidine kinase
CELL2_02755	ENOG4105EYU	Glutamine amido-transferase
CELL2_02760	ENOG4105CBC	glutamate synthase
CELL2_02765	ENOG4105BZ8	glutamate synthase
CELL2_02785	ENOG41088YS	Glycosyl transferase (Group 1
CELL2_02795	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CELL2_02800	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CELL2_02815	ENOG4105CEN	a g-specific adenine glycosylase
CELL2_02820	ENOG4108TVJ	Nitroreductase
CELL2_02830	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CELL2_02835	ENOG4108RCM	Nitroreductase
CELL2_02850	ENOG4105CJ1	ABC, transporter
CELL2_02860	ENOG4105EJ9	Membrane
CELL2_02865	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
CELL2_02870	ENOG4105VN1	Heat shock protein
CELL2_02875	ENOG4105CFG	Acts as a chaperone (By similarity)
CELL2_02880	ENOG4105BZS	acriflavin resistance protein
CELL2_02885	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
CELL2_02890	ENOG4105EHU	Circadian clock protein KaiC
CELL2_02905	ENOG4105C8Q	Methyl-accepting chemotaxis
CELL2_02920	ENOG4105CSM	endonuclease III
CELL2_02925	ENOG4105DFM	M18 family aminopeptidase
CELL2_02965	ENOG4105DXN	mazG family
CELL2_02985	ENOG4105CBD	Diacylglycerol kinase
CELL2_03000	ENOG4105C7B	Threonine dehydratase
CELL2_03015	ENOG410624X	efflux transporter, rnd family, mfp subunit
CELL2_03020	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CELL2_03025	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CELL2_03040	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CELL2_03045	ENOG4105D49	3-dehydroquinate synthase
CELL2_03055	ENOG4108237	shikimate dehydrogenase
CELL2_03060	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CELL2_03070	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
CELL2_03095	ENOG4105CCT	upf0313 protein
CELL2_03100	ENOG4105F6J	Alpha beta hydrolase fold
CELL2_03105	ENOG4107VJ5	dihydroorotase
CELL2_03110	ENOG4105I47	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
CELL2_03115	ENOG4107W93	Dihydroorotate dehydrogenase
CELL2_03120	ENOG4107YPM	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CELL2_03125	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CELL2_03130	ENOG4105EFZ	amidohydrolase
CELL2_03145	ENOG4108JQ1	Dehydrogenase
CELL2_03150	ENOG4106KNT	transcriptional regulator
CELL2_03155	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
CELL2_03160	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CELL2_03170	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CELL2_03210	ENOG4105CPC	Aldo Keto reductase
CELL2_03235	ENOG4105CJQ	hydrolase, family 31
CELL2_03250	ENOG41061GT	Aldolase
CELL2_03260	ENOG4105CPQ	Dehydrogenase
CELL2_03265	ENOG4105CHR	reductase
CELL2_03270	ENOG4105D7K	pfkb domain protein
CELL2_03295	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CELL2_03300	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CELL2_03305	ENOG4105BZN	citrate synthase
CELL2_03310	ENOG4107UUY	ec 2.7.1.11
CELL2_03315	ENOG4105BZ1	(ABC) transporter
CELL2_03320	ENOG4105BZ1	(ABC) transporter
CELL2_03330	ENOG4108MDK	Dehydrogenase
CELL2_03335	ENOG4105CMG	Carbohydrate kinase
CELL2_03340	ENOG4105CR5	Class II aldolase adducin family protein
CELL2_03345	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CELL2_03360	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
CELL2_03385	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CELL2_03390	ENOG4105D2N	Aldolase
CELL2_03395	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CELL2_03415	ENOG4105C3R	Methionine synthase
CELL2_03420	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CELL2_03425	ENOG4105K70	DNA-binding protein
CELL2_03430	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CELL2_03435	ENOG4105I08	Pseudouridine synthase
CELL2_03445	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CELL2_03450	ENOG4105CJ3	phosphate transporter
CELL2_03460	ENOG4105CPF	Cell wall formation (By similarity)
CELL2_03465	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CELL2_03470	ENOG4105EQI	Metal Dependent Phosphohydrolase
CELL2_03480	ENOG4105VB9	50S ribosomal protein l28
CELL2_03485	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CELL2_03490	ENOG41085R6	UPF0102 protein
CELL2_03495	ENOG41084A9	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CELL2_03500	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CELL2_03505	ENOG4105C79	DNA protecting protein DprA
CELL2_03510	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
CELL2_03520	ENOG4105DZB	Electron transport complex
CELL2_03530	ENOG4105D6A	Electron transport complex
CELL2_03535	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CELL2_03560	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CELL2_03570	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CELL2_03585	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CELL2_03590	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CELL2_03595	ENOG4105CNI	cell division protein FtsW
CELL2_03600	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CELL2_03605	ENOG4105DFU	Cell wall formation (By similarity)
CELL2_03620	ENOG4107QIZ	NADH dehydrogenase
CELL2_03625	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
CELL2_03635	ENOG4105K6H	D-cysteine desulfhydrase
CELL2_03640	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CELL2_03650	ENOG4108JJB	ABC transporter
CELL2_03655	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CELL2_03660	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CELL2_03665	ENOG4105W2B	Flagellar assembly protein
CELL2_03680	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CELL2_03685	ENOG4105KME	endoribonuclease L-psp
CELL2_03690	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CELL2_03700	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CELL2_03705	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CELL2_03715	ENOG4105CTQ	phosphohexokinase
CELL2_03720	ENOG4105CA9	Pyruvate kinase
CELL2_03725	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
CELL2_03730	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CELL2_03755	ENOG4107QHI	-hydrogenase
CELL2_03760	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
CELL2_03765	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CELL2_03770	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CELL2_03775	ENOG4107R56	PP-loop domain protein
CELL2_03785	ENOG4107R33	ppx gppa phosphatase
CELL2_03790	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CELL2_03795	ENOG4105C4B	ABC transporter, permease
CELL2_03805	ENOG4105MCT	stage V sporulation protein S
CELL2_03810	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CELL2_03815	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
CELL2_03820	ENOG4105S10	periplasmic binding protein
CELL2_03830	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CELL2_03845	ENOG4105C4K	Nad synthetase
CELL2_03850	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CELL2_03870	ENOG4105C25	Primosomal protein n'
CELL2_03885	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CELL2_03890	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CELL2_03895	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
CELL2_03900	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
CELL2_03905	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CELL2_03910	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
CELL2_03920	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
CELL2_03925	ENOG4105C8T	Leucyl-tRNA synthetase
CELL2_03930	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CELL2_03935	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CELL2_03940	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CELL2_03970	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CELL2_03975	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CELL2_03990	ENOG4105G6Z	alkaline phosphatase
CELL2_03995	ENOG4105CQC	Prephenate dehydratase
CELL2_04015	ENOG41085U1	50S ribosomal protein L32
CELL2_04020	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CELL2_04025	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CELL2_04030	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CELL2_04035	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CELL2_04040	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CELL2_04050	ENOG4105BZU	Histidine kinase
CELL2_04055	ENOG4105CRQ	synthase (Component I)
CELL2_04060	ENOG4105DDQ	anthranilate synthase
CELL2_04065	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CELL2_04070	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CELL2_04075	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CELL2_04080	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CELL2_04085	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CELL2_04095	ENOG4105C3M	thioredoxin reductase
CELL2_04100	ENOG4108W2Y	isochorismatase
CELL2_04105	ENOG4105I03	Flagellin
CELL2_04120	ENOG4107QSA	Oxaloacetate decarboxylase
CELL2_04130	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
CELL2_04135	ENOG41080V6	ABC-3 protein
CELL2_04140	ENOG4105FDK	ABC transporter
CELL2_04160	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CELL2_04165	ENOG4108TVJ	Nitroreductase
CELL2_04185	ENOG4105CMG	Carbohydrate kinase
CELL2_04190	ENOG4105C2J	ABC transporter
CELL2_04205	ENOG4105CNN	ABC, transporter
CELL2_04220	ENOG4105E2R	ROK family
CELL2_04230	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CELL2_04255	ENOG4105UIB	(ABC) transporter
CELL2_04260	ENOG4108JQ9	ABC transporter
CELL2_04265	ENOG4105DIH	basic membrane
CELL2_04275	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CELL2_04295	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CELL2_04300	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
CELL2_04345	ENOG4105CJR	Integral membrane protein (MviN
CELL2_04365	ENOG4105DTJ	flagellar hook-associated protein
CELL2_04370	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
CELL2_04375	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CELL2_04380	ENOG4105EHG	Permease protein
CELL2_04385	ENOG4105E0A	ABC, transporter
CELL2_04390	ENOG4105I82	acetyl xylan esterase
CELL2_04395	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
CELL2_04400	ENOG4108JQ7	(ABC) transporter
CELL2_04405	ENOG4105C3U	ABC transporter
CELL2_04410	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CELL2_04415	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CELL2_04435	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
CELL2_04440	ENOG4105DEI	Mannitol dehydrogenase
CELL2_04450	ENOG4108UHU	Aldolase
CELL2_04455	ENOG4107258	Transcriptional regulator
CELL2_04460	ENOG4105D2H	Uronic isomerase
CELL2_04475	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
CELL2_04480	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CELL2_04485	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CELL2_04490	ENOG4105C3U	ABC transporter
CELL2_04495	ENOG4108JQ7	(ABC) transporter
CELL2_04505	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
CELL2_04525	ENOG4105CE1	Ferrous iron transport protein b
CELL2_04560	ENOG4105BZ1	(ABC) transporter
CELL2_04565	ENOG4105DC7	peptidase M24
CELL2_04570	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CELL2_04580	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
CELL2_04585	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
CELL2_04590	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CELL2_04645	ENOG4108JQ7	(ABC) transporter
CELL2_04680	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CELL2_04685	ENOG4105KJJ	Uncharacterized ACR, COG1993
CELL2_04690	ENOG4105WMR	Protein CrcB homolog
CELL2_04695	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CELL2_04700	ENOG4105DDK	oxidoreductase, beta subunit
CELL2_04705	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CELL2_04710	ENOG4105WGB	oxidoreductase, delta subunit
CELL2_04715	ENOG4105EJ5	oxidoreductase gamma subunit
CELL2_04720	ENOG4105C8Q	Methyl-accepting chemotaxis
CELL2_04730	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
CELL2_04740	ENOG4107QIZ	NADH dehydrogenase
CELL2_04750	ENOG4106IPI	cyclase, family
CELL2_04760	ENOG4105DTQ	mandelate racemase muconate lactonizing
CELL2_04770	ENOG4105CGH	5'-nucleotidase
CELL2_04780	ENOG4108RE9	Phosphodiesterase
CELL2_04785	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CELL2_04790	ENOG4105VEQ	Cold shock protein
CELL2_04800	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
CELL2_04810	ENOG4107U53	septum site-determining protein minD
CELL2_04815	ENOG4105DAN	ATP-dependent protease
CELL2_04820	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
CELL2_04825	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CELL2_04855	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CELL2_04860	ENOG41081HM	2'-5' rna ligase
CELL2_04865	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CELL2_04870	ENOG4108489	Modulates RecA activity (By similarity)
CELL2_04875	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
CELL2_04880	ENOG4105ETE	Transcriptional regulator (LacI family
CELL2_04900	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
CELL2_04905	ENOG4105DRS	transport system, permease
CELL2_04930	ENOG4105E2V	Glycosyltransferase 36
CELL2_04940	ENOG4107T3P	ABC, transporter
CELL2_04955	ENOG4105E2R	ROK family
CELL2_04965	ENOG4108IUM	Glycogen debranching enzyme
CELL2_04990	ENOG4105CG3	alpha amylase, catalytic region
CELL2_04995	ENOG4107FKK	extracellular solute-binding protein family 1
CELL2_05000	ENOG4105D56	permease protein
CELL2_05005	ENOG4105EG2	ABC transporter, permease
CELL2_05010	ENOG4108IUK	alpha amylase, catalytic
CELL2_05025	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CELL2_05030	ENOG4108JQ7	(ABC) transporter
CELL2_05040	ENOG4107V4V	glycoside hydrolase family 4
CELL2_05045	ENOG4108T5G	Adenylate
CELL2_05060	ENOG4105BZU	Histidine kinase
CELL2_05065	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CELL2_05070	ENOG4108R6K	riboflavin synthase, subunit alpha
CELL2_05075	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CELL2_05080	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CELL2_05090	ENOG4105EPW	hflc protein
CELL2_05095	ENOG4107QJR	hflk protein
CELL2_05100	ENOG4105GRF	N-glycosylase DNA lyase
CELL2_05105	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CELL2_05115	ENOG4105FGV	Chromate
CELL2_05120	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CELL2_05145	ENOG410695F	Crispr-associated protein, Csm1 family
CELL2_05155	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
CELL2_05165	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
CELL2_05180	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CELL2_05225	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CELL2_05230	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CELL2_05260	ENOG4105BZU	Histidine kinase
CELL2_05290	ENOG4105C8Y	Acetylornithine aminotransferase
CELL2_05295	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CELL2_05305	ENOG4105CH7	arginosuccinase
CELL2_05325	ENOG4105CHV	Transcription elongation factor NusA
CELL2_05330	ENOG4105I3K	Ferric uptake regulator, Fur family
CELL2_05355	ENOG4105DP4	dak2 domain fusion protein ylov
CELL2_05390	ENOG4105CKU	formyltetrahydrofolate synthetase
CELL2_05405	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CELL2_05410	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CELL2_05415	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CELL2_05445	ENOG4105CKM	Branched-chain carboxylic acid kinase
CELL2_05450	ENOG4107RE7	phosphate butyryltransferase
CELL2_05455	ENOG4105CKM	Branched-chain carboxylic acid kinase
CELL2_05465	ENOG4105C5W	Aldolase
CELL2_05470	ENOG4105CPC	Aldo Keto reductase
CELL2_05475	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
CELL2_05480	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CELL2_05485	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CELL2_05500	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
CELL2_05505	ENOG4105CDU	Replicative dna helicase
CELL2_05515	ENOG4105QGT	Phosphate uptake regulator
CELL2_05530	ENOG4105DFA	alanine racemase domain protein
CELL2_05535	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CELL2_05560	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CELL2_05565	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
CELL2_05570	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
CELL2_05595	ENOG4107WUB	V-type ATPase 116 kDa subunit
CELL2_05620	ENOG4105CHR	reductase
CELL2_05625	ENOG4105CD3	dihydroorotase
CELL2_05640	ENOG41082BV	acetyltransferase
CELL2_05655	ENOG4105DJV	ribulose-phosphate 3-epimerase
CELL2_05660	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CELL2_05680	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CELL2_05700	ENOG4105CHW	UPF0052 protein
CELL2_05705	ENOG4105CIE	May be required for sporulation (By similarity)
CELL2_05710	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CELL2_05720	ENOG4105CRK	lysyL-tRNA synthetase
CELL2_05735	ENOG4105E0M	Sulfatase
CELL2_05755	ENOG4108ESY	Metal dependent phosphohydrolase
CELL2_05760	ENOG4105CHM	Aminotransferase
CELL2_05765	ENOG4105DR4	Methyltransferase
CELL2_05785	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CELL2_05810	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CELL2_05815	ENOG41065EC	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CELL2_05820	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CELL2_05825	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
CELL2_05830	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CELL2_05840	ENOG4105VEQ	Cold shock protein
CELL2_05845	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CELL2_05865	ENOG4105CPI	Metal Dependent Phosphohydrolase
CELL2_05905	ENOG4105D00	flagellar biosynthetic protein flhB
CELL2_05925	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CELL2_05935	ENOG4107Y49	methyltransferase
CELL2_05940	ENOG4108JJB	ABC transporter
CELL2_05945	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CELL2_05950	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CELL2_05965	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CELL2_05970	ENOG410857I	Binds directly to 16S ribosomal RNA (By similarity)
CELL2_05980	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CELL2_05985	ENOG4105BZU	Histidine kinase
CELL2_06000	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CELL2_06015	ENOG4108WF2	Metal Dependent Phosphohydrolase
CELL2_06035	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CELL2_06050	ENOG4105CXT	aspartate transcarbamylase
CELL2_06055	ENOG41084X0	Dihydrofolate reductase
CELL2_06065	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
CELL2_06070	ENOG4108IUW	ABC transporter
CELL2_06090	ENOG4107RH8	nuclease SbcCD subunit D
CELL2_06100	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CELL2_06105	ENOG4105K8N	protein family UPF0079, ATPase
CELL2_06120	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CELL2_06125	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CELL2_06155	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CELL2_06165	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
CELL2_06175	ENOG4105C2M	dna polymerase I
CELL2_06180	ENOG4108W5Z	CheC domain protein
CELL2_06195	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
CELL2_06200	ENOG410855G	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CELL2_06205	ENOG41084Y9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CELL2_06210	ENOG41085KK	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CELL2_06215	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CELL2_06220	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CELL2_06225	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CELL2_06230	ENOG41082J0	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CELL2_06235	ENOG4105EPR	degv family
CELL2_06240	ENOG4105MS2	ribosomal subunit Interface protein
CELL2_06245	ENOG4105C03	ribonuclease
CELL2_06250	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CELL2_06255	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CELL2_06260	ENOG41079KZ	Major Facilitator Superfamily
CELL2_06265	ENOG4108Z3G	3H domain protein
CELL2_06270	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CELL2_06285	ENOG4105EMN	RNA polymerase sigma factor
CELL2_06290	ENOG4106M28	alanine racemase domain protein
CELL2_06295	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
CELL2_06300	ENOG4105SFS	phosphoesterase RecJ domain protein
CELL2_06305	ENOG4105BZU	Histidine kinase
CELL2_06310	ENOG4105D1F	ATP-binding protein
CELL2_06315	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CELL2_06320	ENOG4107N8V	50s ribosomal protein L35
CELL2_06325	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CELL2_06350	ENOG4105D1Z	hydroxypyruvate reductase
CELL2_06355	ENOG4105MJ2	Competence protein
CELL2_06380	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CELL2_06385	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CELL2_06390	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CELL2_06400	ENOG4105DX0	Hemolysin A
CELL2_06410	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CELL2_06420	ENOG4105C3F	Signal peptidase i
CELL2_06425	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CELL2_06430	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
CELL2_06435	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CELL2_06440	ENOG410836E	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CELL2_06445	ENOG41084QK	UPF0109 protein
CELL2_06450	ENOG4105K5M	30s ribosomal protein S16
CELL2_06455	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CELL2_06460	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CELL2_06485	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CELL2_06495	ENOG4105W5Q	DNA repair protein (RadC
CELL2_06500	ENOG4108Z03	MAF-like protein
CELL2_06515	ENOG4105CJ2	(LipO)protein
CELL2_06525	ENOG4105NBF	ammecr1 domain protein
CELL2_06530	ENOG4105CBJ	Metal-dependent enzyme
CELL2_06535	ENOG4107UKG	Glycosyl transferase, family 4
CELL2_06545	ENOG4105DCI	Phosphohydrolase
CELL2_06550	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CELL2_06555	ENOG41084RN	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CELL2_06565	ENOG4105KTQ	flagellar basal-body rod protein
CELL2_06570	ENOG4105CGA	flagellar basal-body rod protein FlgG
CELL2_06580	ENOG4105TZT	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CELL2_06585	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CELL2_06595	ENOG4105EPH	radical SAM domain protein
CELL2_06615	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CELL2_06620	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CELL2_06625	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CELL2_06635	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CELL2_06645	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CELL2_06650	ENOG4105CH2	amidohydrolase
CELL2_06665	ENOG4105CDE	UPF0348 protein
CELL2_06670	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CELL2_06690	ENOG4105CTJ	Metal Dependent Phosphohydrolase
CELL2_06695	ENOG4105C9A	Phoh family
CELL2_06705	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CELL2_06710	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CELL2_06715	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CELL2_06720	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CELL2_06725	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CELL2_06730	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CELL2_06735	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CELL2_06740	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CELL2_06745	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CELL2_06750	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CELL2_06755	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CELL2_06760	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CELL2_06765	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CELL2_06770	ENOG41084ME	50s ribosomal protein l29
CELL2_06775	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CELL2_06780	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CELL2_06785	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CELL2_06795	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CELL2_06800	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CELL2_06805	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CELL2_06810	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CELL2_06815	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CELL2_06820	ENOG4105VPB	50S ribosomal protein L30
CELL2_06825	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CELL2_06830	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CELL2_06835	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CELL2_06845	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CELL2_06850	ENOG41086MH	50S ribosomal protein L36
CELL2_06855	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CELL2_06860	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CELL2_06865	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CELL2_06870	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CELL2_06875	ENOG4108ZT0	50S ribosomal protein l17
CELL2_06880	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CELL2_06885	ENOG4105DKQ	ROK family
CELL2_06890	ENOG4105EPR	degv family
CELL2_06900	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CELL2_06905	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CELL2_06910	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CELL2_06920	ENOG41085QA	50S ribosomal protein l34
CELL2_06930	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CELL2_06935	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CELL2_06960	ENOG4105K46	50S ribosomal protein l27
CELL2_06965	ENOG41081BK	membrane protein-like protein
CELL2_06970	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CELL2_06980	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CELL2_06985	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CELL2_06990	ENOG4108JA2	transcriptioN-repair coupling factor
CELL2_07005	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CELL2_07015	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CELL2_07020	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CELL2_07030	ENOG41084GC	stage II sporulation protein
CELL2_07040	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CELL2_07050	ENOG4107RFW	hydrolase family 57
CELL2_07080	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
CELL2_07085	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
CELL2_07090	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CELL2_07095	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CELL2_07100	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
CELL2_07105	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
CELL2_07110	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
CELL2_07115	ENOG4107QHI	-hydrogenase
CELL2_07120	ENOG4107QIZ	NADH dehydrogenase
CELL2_07125	ENOG4105GKE	subunit e
CELL2_07140	ENOG4105Y5S	NADH ubiquinone oxidoreductase, 24 kD
CELL2_07150	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CELL2_07155	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CELL2_07165	ENOG4105DIW	FeS assembly protein SUFB
CELL2_07170	ENOG4105ECY	inositol monophosphatase
CELL2_07175	ENOG4108HKT	sucrose-6-phosphate hydrolase
CELL2_07200	ENOG4108JQ1	Dehydrogenase
CELL2_07205	ENOG4105C5R	Aminotransferase
CELL2_07210	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CELL2_07225	ENOG4105KNE	Phosphatidate cytidylyltransferase
CELL2_07240	ENOG4107S82	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CELL2_07245	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CELL2_07270	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CELL2_07275	ENOG4106H78	methyltransferase
CELL2_07280	ENOG41083IT	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CELL2_07290	ENOG4105C89	phosphohexose isomerase
CELL2_07295	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CELL2_07300	ENOG4107SJN	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CELL2_07315	ENOG4108TSD	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CELL2_07320	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CELL2_07325	ENOG4105D38	putrescine abc transporter
CELL2_07330	ENOG4105F38	ABC transporter, permease
CELL2_07335	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CELL2_07340	ENOG4107RUE	extracellular solute-binding protein family 1
CELL2_07345	ENOG4105CVJ	phosphoglycerate mutase
CELL2_07355	ENOG4107YH3	SUF system FeS assembly protein, NifU family
CELL2_07360	ENOG4105C9B	Cysteine desulfurase
CELL2_07370	ENOG4105DIW	FeS assembly protein SUFB
CELL2_07375	ENOG4105C3K	feS assembly ATPase SufC
CELL2_07385	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CELL2_07390	ENOG4108ZC9	flagellar basal-body rod protein flgc
CELL2_07395	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CELL2_07400	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CELL2_07405	ENOG4105CZX	twitching motility protein
CELL2_07410	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CELL2_07415	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CELL2_07420	ENOG4105BZU	Histidine kinase
CELL2_07445	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CELL2_07460	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CELL2_07465	ENOG4105E5G	Alpha beta hydrolase fold
CELL2_07470	ENOG4107Z0G	Domain of unknown function DUF20
CELL2_07480	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CELL2_07485	ENOG4105C1V	Peptidase, M16
CELL2_07490	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CELL2_07495	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CELL2_07570	ENOG4106HX1	Uncharacterised protein family (UPF0150)
CELL2_07580	ENOG4105ZVY	2-oxoisovalerate dehydrogenase, E1 component beta subunit
CELL2_07615	ENOG4108IUW	ABC transporter
CELL2_07635	ENOG4108FN7	Aldo keto reductase
CELL2_07645	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CELL2_07660	ENOG4105W06	Cupin 2, conserved barrel domain protein
CELL2_07665	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CELL2_07690	ENOG4105C98	muts2 protein
CELL2_07695	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CELL2_07720	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CELL2_07735	ENOG4105C28	cystathionine
CELL2_07740	ENOG4107QW8	radical SAM domain protein
CELL2_07770	ENOG4105CVA	phosphate
CELL2_07785	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CELL2_07790	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CELL2_07795	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CELL2_07810	ENOG4105BZ1	(ABC) transporter
CELL2_07815	ENOG4105CHM	Aminotransferase
CELL2_07820	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CELL2_07825	ENOG4105C4K	Nad synthetase
CELL2_07840	ENOG4107QNG	Phosphoribosylglycinamide synthetase
CELL2_07845	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CELL2_07850	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CELL2_07860	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
CELL2_07865	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CELL2_07870	ENOG4108A1T	Phosphoribosylformylglycinamidine synthase, purS
CELL2_07905	ENOG4105C4R	Atp-dependent dna helicase
CELL2_07930	ENOG4108IJ9	(ABC) transporter
CELL2_07935	ENOG4105C8I	hydrolase, family 38
CELL2_07940	ENOG4105IRK	Glycosyl transferase (Group 1
CELL2_07945	ENOG4106J7S	Glycosyl transferase, family 2
CELL2_07965	ENOG4107QRA	Extracellular solute-binding protein, family 5
CELL2_07970	ENOG4105CKB	glycosidase
CELL2_07975	ENOG4105E2R	ROK family
CELL2_07980	ENOG4108J59	Extracellular solute-binding protein, family 5
CELL2_07995	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CELL2_08005	ENOG4108JQ7	(ABC) transporter
CELL2_08010	ENOG4105ETE	Transcriptional regulator (LacI family
CELL2_08020	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CELL2_08025	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CELL2_08030	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CELL2_08045	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CELL2_08055	ENOG4105D65	subunit l
CELL2_08070	ENOG410684G	monovalent cation H antiporter subunit F
CELL2_08075	ENOG4105SC1	monovalent cation H antiporter subunit E
CELL2_08080	ENOG4105ETE	Transcriptional regulator (LacI family
CELL2_08090	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
CELL2_08095	ENOG4105DRS	transport system, permease
CELL2_08110	ENOG4105C3U	ABC transporter
CELL2_08115	ENOG4105CNT	hydrolase family 2
CELL2_08120	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
CELL2_08125	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
CELL2_08130	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CELL2_08140	ENOG4105D7V	transposase
CELL2_08145	ENOG4105BZU	Histidine kinase
CELL2_08155	ENOG4107WSY	Domain of unknown function DUF20
CELL2_08165	ENOG4108Z5K	methylglyoxal synthase
CELL2_08170	ENOG4105BZU	Histidine kinase
CELL2_08175	ENOG4107SET	aldo keto reductase
CELL2_08180	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CELL2_08185	ENOG4108YZ4	nudix hydrolase
CELL2_08195	ENOG4105MQ3	flagellar protein FliS
CELL2_08200	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CELL2_08205	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CELL2_08210	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CELL2_08220	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CELL2_08225	ENOG4105CHR	reductase
CELL2_08230	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CELL2_08240	ENOG4105CSA	Coproporphyrinogen iii oxidase
CELL2_08245	ENOG4105DQU	oxidoreductase, subunit beta
CELL2_08260	ENOG4108KHP	Diguanylate cyclase
CELL2_08265	ENOG4105E8R	UPF0173 metal-dependent hydrolase
CELL2_08270	ENOG4105CJW	magnesium transporter
CELL2_08300	ENOG41067S9	phage shock protein C, PspC
CELL2_08305	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CELL2_08310	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CELL2_08315	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CELL2_08325	ENOG4108JQ7	(ABC) transporter
CELL2_08330	ENOG4105DEF	Extracellular solute-binding protein, family 5
CELL2_08335	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CELL2_08350	ENOG4107QIV	Cytochrome c biogenesis protein
CELL2_08355	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CELL2_08360	ENOG4108IV0	ABC, transporter
CELL2_08365	ENOG4105C0Z	ABC transporter
CELL2_08370	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CELL2_08375	ENOG4105C32	Amino acid ABC transporter (Permease)
CELL2_08400	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CELL2_08405	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CELL2_08410	ENOG4107RE7	phosphate butyryltransferase
CELL2_08415	ENOG41083B7	nucleosidase (EC 3.2.2.9)
CELL2_08445	ENOG4107V1F	Flagellar hook-associated 2 domain-containing protein
CELL2_08460	ENOG4105BZ7	extracellular solute-binding protein family 1
CELL2_08530	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CELL2_08550	ENOG4108RE9	Phosphodiesterase
CELL2_08570	ENOG4105DBV	ornithine carbamoyltransferase
CELL2_08575	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CELL2_08580	ENOG4105C83	adenylosuccinate lyase
CELL2_08585	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CELL2_08610	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CELL2_08620	ENOG4107VEG	TrkA-N domain protein
CELL2_08635	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CELL2_08640	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CELL2_08645	ENOG4106FU4	Archease protein family (MTH1598/TM1083)
CELL2_08655	ENOG410682B	stage II sporulation protein
CELL2_08660	ENOG4108YZG	isomerase
CELL2_08700	ENOG4105DET	Rhamnulokinase
CELL2_08710	ENOG4105C9F	isomerase
CELL2_08720	ENOG4105MVE	transcriptional regulator
CELL2_08725	ENOG4107V4V	glycoside hydrolase family 4
CELL2_08750	ENOG4105CNT	hydrolase family 2
CELL2_08770	ENOG4105MCT	stage V sporulation protein S
CELL2_08780	ENOG4107SVH	Potassium channel protein
CELL2_08785	ENOG4108531	cuta1 divalent ion tolerance protein
CELL2_08795	ENOG4108IUZ	ABC transporter
CELL2_08805	ENOG4105KQC	Competence protein
CELL2_08815	ENOG4105CN9	Peptidase m42 family protein
CELL2_08820	ENOG4105CN9	Peptidase m42 family protein
CELL2_08825	ENOG4105CN9	Peptidase m42 family protein
CELL2_08840	ENOG4108J9M	Transporter
CELL2_08850	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CELL2_08855	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CELL2_08865	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CELL2_08870	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CELL2_08875	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CELL2_08880	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CELL2_08885	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CELL2_08890	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CELL2_08895	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CELL2_08925	ENOG4105CIG	ABC transporter
CELL2_08950	ENOG4107RCC	Major Facilitator Superfamily
CELL2_08975	ENOG4105D82	Glutamate dehydrogenase
CELL2_09025	ENOG4107SET	aldo keto reductase
CELL2_09030	ENOG4105CF7	AraC family transcriptional regulator
CELL2_09040	ENOG41080HT	Transcriptional regulator, arsr family
CELL2_09045	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
CELL2_09060	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CELL2_09065	ENOG4105C98	muts2 protein
CELL2_09070	ENOG4105HA9	of methanol dehydrogenase type
CELL2_09075	ENOG4108V0P	LemA family
CELL2_09080	ENOG4108RVA	ribokinase
CELL2_09095	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
CELL2_09100	ENOG4105C2J	ABC transporter
CELL2_09115	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CELL2_09150	ENOG4105C5F	glutamine synthetase
CELL2_09165	ENOG4105EI2	Pseudouridine synthase
CELL2_09170	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CELL2_09185	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CELL2_09190	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CELL2_09195	ENOG4107R3E	Citrate transporter
CELL2_09215	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CELL2_09220	ENOG4105EZM	VWA-like domain (DUF2201)
CELL2_09225	ENOG41063SX	
CELL2_09230	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein