locus-tag	class	description
CELL2_00010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CELL2_00025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CELL2_00025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CELL2_00030	COG0741	lytic transglycosylase activity
CELL2_00045	COG0840	transmembrane signaling receptor activity
CELL2_00065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CELL2_00070	COG1392	Phosphate transport regulator
CELL2_00090	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CELL2_00095	COG1684	flagellar biosynthetic protein fliR
CELL2_00100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CELL2_00105	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CELL2_00110	COG1419	protein localization to endoplasmic reticulum
CELL2_00115	COG0455	bacterial-type flagellum organization
CELL2_00125	COG1776	CheC inhibitor of MCP methylation
CELL2_00130	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CELL2_00135	COG1191	sigma factor activity
CELL2_00165	COG2359	stage V sporulation protein S
CELL2_00170	COG1085	galactose-1-phosphate uridylyltransferase
CELL2_00175	COG0297	glycogen (starch) synthase activity
CELL2_00185	COG1968	undecaprenyl-diphosphatase activity
CELL2_00190	COG2239	Acts as a magnesium transporter
CELL2_00195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CELL2_00200	COG0750	zinc metalloprotease
CELL2_00205	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CELL2_00215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CELL2_00245	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CELL2_00250	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CELL2_00260	COG0674	pyruvate-flavodoxin oxidoreductase activity
CELL2_00260	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CELL2_00265	COG0148	phosphopyruvate hydratase activity
CELL2_00270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CELL2_00280	COG1214	PFAM Peptidase M22, glycoprotease
CELL2_00285	COG0542	response to heat
CELL2_00290	COG0275	rRNA processing
CELL2_00310	COG0492	ferredoxin-NADP+ reductase activity
CELL2_00335	COG1234	tRNA 3'-trailer cleavage
CELL2_00355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CELL2_00360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CELL2_00365	COG1862	Preprotein translocase
CELL2_00380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CELL2_00385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CELL2_00390	COG1639	'signal transduction protein
CELL2_00395	COG5002	protein histidine kinase activity
CELL2_00425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CELL2_00430	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CELL2_00435	COG0295	cytidine deaminase activity
CELL2_00440	COG4535	Mg2 and Co2 transporter CorC
CELL2_00445	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CELL2_00455	COG2201	protein-glutamate methylesterase activity
CELL2_00470	COG0772	Belongs to the SEDS family
CELL2_00485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CELL2_00490	COG0849	cell division
CELL2_00500	COG0187	DNA topoisomerase II activity
CELL2_00510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CELL2_00515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELL2_00530	COG3842	ATPase activity
CELL2_00550	COG1309	transcriptional regulator
CELL2_00555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELL2_00555	COG0072	phenylalanine-tRNA ligase activity
CELL2_00560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CELL2_00565	COG1979	alcohol dehydrogenase
CELL2_00575	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CELL2_00595	COG0534	Mate efflux family protein
CELL2_00605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CELL2_00610	COG0395	ABC-type sugar transport system, permease component
CELL2_00625	COG1472	Belongs to the glycosyl hydrolase 3 family
CELL2_00630	COG1940	carbohydrate kinase activity
CELL2_00630	COG1846	Transcriptional regulator
CELL2_00635	COG0450	alkyl hydroperoxide reductase
CELL2_00645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CELL2_00650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CELL2_00655	COG0504	CTP synthase activity
CELL2_00660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CELL2_00665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CELL2_00670	COG2070	2-Nitropropane dioxygenase
CELL2_00675	COG1268	BioY protein
CELL2_00680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CELL2_00685	COG2045	Belongs to the ComB family
CELL2_00710	COG1131	(ABC) transporter
CELL2_00715	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CELL2_00720	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CELL2_00725	COG0351	phosphomethylpyrimidine kinase
CELL2_00725	COG1992	Thiamine-phosphate synthase
CELL2_00735	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CELL2_00740	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
CELL2_00750	COG1659	Linocin_M18 bacteriocin protein
CELL2_00800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CELL2_00815	COG1774	PSP1 C-terminal conserved region
CELL2_00835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CELL2_00840	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CELL2_00845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CELL2_00855	COG1131	(ABC) transporter
CELL2_00865	COG0393	Putative heavy-metal-binding
CELL2_00870	COG0052	Belongs to the universal ribosomal protein uS2 family
CELL2_00910	COG0426	domain, Protein
CELL2_00915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELL2_00920	COG2226	methyltransferase
CELL2_00925	COG1486	melibiose metabolic process
CELL2_00930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CELL2_00945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CELL2_00950	COG0793	Belongs to the peptidase S41A family
CELL2_00965	COG0438	transferase activity, transferring glycosyl groups
CELL2_00975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CELL2_00980	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CELL2_00990	COG2199	diguanylate cyclase activity
CELL2_00990	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CELL2_01005	COG1482	cell wall glycoprotein biosynthetic process
CELL2_01030	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CELL2_01040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CELL2_01055	COG0312	modulator of DNA gyrase
CELL2_01060	COG0312	modulator of DNA gyrase
CELL2_01080	COG0557	exoribonuclease II activity
CELL2_01085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CELL2_01095	COG0215	cysteine-tRNA ligase activity
CELL2_01100	COG0835	chemotaxis
CELL2_01105	COG0511	ligase activity, forming carbon-carbon bonds
CELL2_01105	COG5016	pyruvate
CELL2_01115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CELL2_01150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CELL2_01155	COG0095	Lipoate-protein ligase
CELL2_01160	COG0357	Ribosomal RNA small subunit methyltransferase G
CELL2_01170	COG1136	(ABC) transporter
CELL2_01175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CELL2_01180	COG1058	Belongs to the CinA family
CELL2_01180	COG1546	Belongs to the CinA family
CELL2_01185	COG2198	Histidine kinase
CELL2_01185	COG0643	Histidine kinase
CELL2_01190	COG0835	chemotaxis
CELL2_01195	COG2201	protein-glutamate methylesterase activity
CELL2_01205	COG1338	Plays a role in the flagellum-specific transport system
CELL2_01220	COG0740	serine-type endopeptidase activity
CELL2_01225	COG0544	peptidyl-prolyl cis-trans isomerase activity
CELL2_01235	COG0736	holo-[acyl-carrier-protein] synthase activity
CELL2_01250	COG0149	triose-phosphate isomerase activity
CELL2_01250	COG0126	phosphoglycerate kinase activity
CELL2_01255	COG0126	phosphoglycerate kinase activity
CELL2_01260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CELL2_01265	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CELL2_01270	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CELL2_01325	COG1360	Flagellar Motor Protein
CELL2_01335	COG1582	Flagellar protein (FlbD)
CELL2_01340	COG1749	Flagellar hook protein flgE
CELL2_01375	COG0084	hydrolase, TatD family'
CELL2_01380	COG1045	serine acetyltransferase
CELL2_01385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CELL2_01400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CELL2_01410	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CELL2_01415	COG1773	rubredoxin
CELL2_01420	COG2033	superoxide reductase activity
CELL2_01425	COG1592	Rubrerythrin
CELL2_01430	COG1476	TRANSCRIPTIONal
CELL2_01435	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CELL2_01440	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CELL2_01445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELL2_01455	COG0561	phosphatase activity
CELL2_01470	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CELL2_01480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CELL2_01545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CELL2_01555	COG0438	transferase activity, transferring glycosyl groups
CELL2_01595	COG0438	transferase activity, transferring glycosyl groups
CELL2_01595	COG0297	glycogen (starch) synthase activity
CELL2_01605	COG1216	Glycosyl transferase, family 2
CELL2_01605	COG1442	glycosyl transferase family 8
CELL2_01625	COG0297	glycogen (starch) synthase activity
CELL2_01625	COG0438	transferase activity, transferring glycosyl groups
CELL2_01630	COG1216	Glycosyl transferase, family 2
CELL2_01705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELL2_01715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CELL2_01720	COG0629	single-stranded DNA binding
CELL2_01725	COG0360	Binds together with S18 to 16S ribosomal RNA
CELL2_01755	COG0395	ABC-type sugar transport system, permease component
CELL2_01760	COG1175	transmembrane transport
CELL2_01770	COG2252	PERMEase
CELL2_01790	COG0768	penicillin binding
CELL2_01805	COG1077	Cell shape determining protein MreB Mrl
CELL2_01810	COG0517	IMP dehydrogenase activity
CELL2_01810	COG1227	inorganic diphosphatase activity
CELL2_01815	COG0697	spore germination
CELL2_01820	COG0673	inositol 2-dehydrogenase activity
CELL2_01845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CELL2_01850	COG0037	tRNA processing
CELL2_01855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CELL2_01860	COG0456	acetyltransferase
CELL2_01865	COG2176	DNA-directed DNA polymerase activity
CELL2_01870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CELL2_01875	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CELL2_01880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CELL2_01885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CELL2_01890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CELL2_01895	COG0552	protein localization to endoplasmic reticulum
CELL2_01915	COG1959	2 iron, 2 sulfur cluster binding
CELL2_01925	COG1489	DNA binding
CELL2_01950	COG0598	Magnesium transport protein CorA
CELL2_01970	COG0505	Belongs to the CarA family
CELL2_01975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CELL2_01980	COG0473	3-isopropylmalate dehydrogenase activity
CELL2_01985	COG0066	3-isopropylmalate dehydratase activity
CELL2_01990	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CELL2_01995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CELL2_02000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CELL2_02010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CELL2_02015	COG0440	acetolactate synthase activity
CELL2_02020	COG0028	Belongs to the TPP enzyme family
CELL2_02025	COG0527	aspartate kinase activity
CELL2_02030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CELL2_02035	COG0083	homoserine kinase activity
CELL2_02040	COG1131	(ABC) transporter
CELL2_02060	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CELL2_02060	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CELL2_02070	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CELL2_02080	COG4717	serine-type aminopeptidase activity
CELL2_02095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CELL2_02100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_02105	COG0601	transmembrane transport
CELL2_02110	COG0747	negative chemotaxis
CELL2_02115	COG4608	Belongs to the ABC transporter superfamily
CELL2_02120	COG2608	mercury ion transmembrane transporter activity
CELL2_02135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CELL2_02140	COG1923	regulation of RNA biosynthetic process
CELL2_02145	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CELL2_02170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CELL2_02175	COG0482	sulfurtransferase activity
CELL2_02200	COG1242	4 iron, 4 sulfur cluster binding
CELL2_02205	COG0442	prolyl-tRNA aminoacylation
CELL2_02210	COG0606	chelatase, subunit chli
CELL2_02220	COG1573	uracil-dna glycosylase
CELL2_02235	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CELL2_02235	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CELL2_02240	COG0459	protein refolding
CELL2_02245	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CELL2_02250	COG0601	transmembrane transport
CELL2_02255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_02270	COG4608	Belongs to the ABC transporter superfamily
CELL2_02280	COG0444	Belongs to the ABC transporter superfamily
CELL2_02295	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CELL2_02300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CELL2_02305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CELL2_02310	COG0180	Tryptophanyl-tRNA synthetase
CELL2_02320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CELL2_02325	COG1595	DNA-templated transcription, initiation
CELL2_02330	COG2890	protein-(glutamine-N5) methyltransferase activity
CELL2_02335	COG2151	metal-sulfur cluster biosynthetic enzyme
CELL2_02345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CELL2_02350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CELL2_02355	COG1116	anion transmembrane transporter activity
CELL2_02380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CELL2_02385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CELL2_02390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CELL2_02395	COG1196	nuclear chromosome segregation
CELL2_02400	COG1335	isochorismatase
CELL2_02410	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CELL2_02435	COG0745	RESPONSE REGULATOR receiver
CELL2_02455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CELL2_02460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CELL2_02465	COG0564	pseudouridine synthase activity
CELL2_02470	COG0587	DNA-directed DNA polymerase activity
CELL2_02480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CELL2_02485	COG0085	RNA polymerase activity
CELL2_02490	COG0222	ribosome binding
CELL2_02495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CELL2_02500	COG0081	regulation of translation
CELL2_02505	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CELL2_02510	COG0250	Participates in transcription elongation, termination and antitermination
CELL2_02515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CELL2_02520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CELL2_02530	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CELL2_02535	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CELL2_02550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CELL2_02560	COG1027	Aspartate ammonia-lyase
CELL2_02565	COG1070	Carbohydrate kinase
CELL2_02590	COG1802	Transcriptional regulator
CELL2_02595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CELL2_02630	COG1172	Belongs to the binding-protein-dependent transport system permease family
CELL2_02640	COG1082	Xylose isomerase domain protein TIM barrel
CELL2_02645	COG3842	ATPase activity
CELL2_02650	COG3833	ABC-type maltose transport systems, permease component
CELL2_02655	COG1175	transmembrane transport
CELL2_02665	COG1082	Xylose isomerase domain protein TIM barrel
CELL2_02675	COG0673	inositol 2-dehydrogenase activity
CELL2_02680	COG1402	creatininase
CELL2_02685	COG1063	alcohol dehydrogenase
CELL2_02690	COG1940	carbohydrate kinase activity
CELL2_02700	COG0739	heme binding
CELL2_02705	COG2201	protein-glutamate methylesterase activity
CELL2_02720	COG1013	pyruvate-flavodoxin oxidoreductase activity
CELL2_02730	COG0347	Belongs to the P(II) protein family
CELL2_02735	COG0004	ammonium transporteR
CELL2_02740	COG1435	thymidine kinase activity
CELL2_02745	COG3850	Histidine kinase
CELL2_02745	COG5002	protein histidine kinase activity
CELL2_02755	COG0067	glutamate synthase
CELL2_02760	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CELL2_02760	COG0069	glutamate synthase activity
CELL2_02765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CELL2_02765	COG0493	'glutamate synthase
CELL2_02785	COG0438	transferase activity, transferring glycosyl groups
CELL2_02795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CELL2_02800	COG0446	pyridine nucleotide-disulphide oxidoreductase
CELL2_02815	COG1194	a g-specific adenine glycosylase
CELL2_02820	COG0778	Nitroreductase
CELL2_02835	COG0778	Nitroreductase
CELL2_02850	COG1131	(ABC) transporter
CELL2_02860	COG0730	response to heat
CELL2_02865	COG4869	propanediol catabolic process
CELL2_02870	COG0071	Belongs to the small heat shock protein (HSP20) family
CELL2_02875	COG0443	Heat shock 70 kDa protein
CELL2_02880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CELL2_02885	COG1438	arginine binding
CELL2_02890	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CELL2_02905	COG0840	transmembrane signaling receptor activity
CELL2_02920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CELL2_02925	COG1362	aminopeptidase activity
CELL2_02965	COG3956	TIGRFAM MazG family protein
CELL2_02985	COG1597	lipid kinase activity
CELL2_03000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CELL2_03015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CELL2_03020	COG1136	(ABC) transporter
CELL2_03025	COG1136	(ABC) transporter
CELL2_03025	COG0577	efflux transmembrane transporter activity
CELL2_03040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CELL2_03045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CELL2_03045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CELL2_03055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CELL2_03060	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CELL2_03070	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CELL2_03095	COG1032	radical SAM domain protein
CELL2_03100	COG1073	alpha beta
CELL2_03105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CELL2_03110	COG0543	2 iron, 2 sulfur cluster binding
CELL2_03115	COG0167	dihydroorotate dehydrogenase activity
CELL2_03120	COG0284	orotidine-5'-phosphate decarboxylase activity
CELL2_03125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CELL2_03130	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CELL2_03145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELL2_03150	COG1737	Transcriptional regulator
CELL2_03155	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_03160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CELL2_03170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CELL2_03210	COG0667	Aldo Keto reductase
CELL2_03230	COG0747	negative chemotaxis
CELL2_03235	COG1501	Belongs to the glycosyl hydrolase 31 family
CELL2_03250	COG1830	Aldolase
CELL2_03255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CELL2_03260	COG1063	alcohol dehydrogenase
CELL2_03265	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_03270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CELL2_03295	COG0066	3-isopropylmalate dehydratase activity
CELL2_03300	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CELL2_03305	COG0372	Belongs to the citrate synthase family
CELL2_03310	COG0205	6-phosphofructokinase activity
CELL2_03315	COG1132	(ABC) transporter
CELL2_03320	COG1132	(ABC) transporter
CELL2_03330	COG0371	Dehydrogenase
CELL2_03340	COG0235	Class ii aldolase
CELL2_03360	COG0395	ABC-type sugar transport system, permease component
CELL2_03365	COG1175	transmembrane transport
CELL2_03385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CELL2_03390	COG0191	fructose-bisphosphate aldolase activity
CELL2_03395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CELL2_03395	COG0574	Belongs to the PEP-utilizing enzyme family
CELL2_03405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CELL2_03405	COG0646	methionine synthase
CELL2_03415	COG0646	methionine synthase
CELL2_03415	COG1410	methionine synthase
CELL2_03420	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CELL2_03425	COG0776	regulation of translation
CELL2_03430	COG0322	excinuclease ABC activity
CELL2_03435	COG1187	pseudouridine synthase activity
CELL2_03445	COG0592	DNA-directed DNA polymerase activity
CELL2_03450	COG0306	phosphate transporter
CELL2_03460	COG1181	Belongs to the D-alanine--D-alanine ligase family
CELL2_03465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CELL2_03480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CELL2_03485	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CELL2_03490	COG0792	nuclease activity
CELL2_03495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CELL2_03500	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CELL2_03505	COG0758	DNA mediated transformation
CELL2_03510	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
CELL2_03510	COG2878	Part of a membrane complex involved in electron transport
CELL2_03520	COG4660	Part of a membrane complex involved in electron transport
CELL2_03530	COG4658	electron transport chain
CELL2_03535	COG4656	Part of a membrane complex involved in electron transport
CELL2_03560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CELL2_03570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CELL2_03585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CELL2_03590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CELL2_03595	COG0772	Belongs to the SEDS family
CELL2_03600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CELL2_03605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CELL2_03635	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CELL2_03640	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CELL2_03640	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CELL2_03650	COG1122	ATPase activity
CELL2_03655	COG1766	The M ring may be actively involved in energy transduction
CELL2_03660	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CELL2_03670	COG1157	protein secretion by the type III secretion system
CELL2_03680	COG0752	glycyl-tRNA synthetase alpha subunit
CELL2_03685	COG0251	oxidation-reduction process
CELL2_03690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CELL2_03700	COG0509	glycine decarboxylation via glycine cleavage system
CELL2_03705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CELL2_03715	COG0205	6-phosphofructokinase activity
CELL2_03720	COG0469	pyruvate kinase activity
CELL2_03725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CELL2_03735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CELL2_03760	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CELL2_03765	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CELL2_03770	COG0542	response to heat
CELL2_03775	COG0037	tRNA processing
CELL2_03785	COG0248	Ppx GppA phosphatase
CELL2_03790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CELL2_03795	COG0390	transport system, permease component
CELL2_03805	COG2359	stage V sporulation protein S
CELL2_03810	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CELL2_03815	COG4139	cobalamin transport
CELL2_03845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CELL2_03845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CELL2_03850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELL2_03870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CELL2_03875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CELL2_03885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CELL2_03890	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CELL2_03895	COG1110	DNA topoisomerase II activity
CELL2_03900	COG1110	DNA topoisomerase II activity
CELL2_03905	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CELL2_03910	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CELL2_03920	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CELL2_03925	COG0495	leucyl-tRNA aminoacylation
CELL2_03930	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CELL2_03935	COG0285	dihydrofolate synthase activity
CELL2_03940	COG0632	four-way junction helicase activity
CELL2_03970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CELL2_03975	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CELL2_03990	COG1785	Belongs to the alkaline phosphatase family
CELL2_04015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CELL2_04020	COG0416	fatty acid biosynthetic process
CELL2_04025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CELL2_04030	COG0799	negative regulation of ribosome biogenesis
CELL2_04035	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CELL2_04040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CELL2_04050	COG0745	RESPONSE REGULATOR receiver
CELL2_04050	COG3706	GGDEF domain
CELL2_04055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CELL2_04060	COG0512	Glutamine amidotransferase of anthranilate synthase
CELL2_04060	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CELL2_04065	COG0134	indole-3-glycerol-phosphate synthase activity
CELL2_04070	COG0135	phosphoribosylanthranilate isomerase activity
CELL2_04075	COG0133	tryptophan synthase activity
CELL2_04080	COG0159	tryptophan synthase activity
CELL2_04085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CELL2_04095	COG0492	ferredoxin-NADP+ reductase activity
CELL2_04100	COG1335	isochorismatase
CELL2_04105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CELL2_04135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CELL2_04140	COG1121	(ABC) transporter
CELL2_04160	COG1509	lysine 2,3-aminomutase activity
CELL2_04165	COG0778	Nitroreductase
CELL2_04185	COG1070	Carbohydrate kinase
CELL2_04190	COG1129	ABC transporter
CELL2_04205	COG1172	Belongs to the binding-protein-dependent transport system permease family
CELL2_04220	COG1940	carbohydrate kinase activity
CELL2_04230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CELL2_04275	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CELL2_04295	COG3116	cell division
CELL2_04295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CELL2_04300	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CELL2_04345	COG0728	peptidoglycan biosynthetic process
CELL2_04365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CELL2_04370	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CELL2_04375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CELL2_04380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CELL2_04385	COG1120	ATPase activity
CELL2_04390	COG3458	cephalosporin-C deacetylase activity
CELL2_04400	COG4608	Belongs to the ABC transporter superfamily
CELL2_04405	COG0444	Belongs to the ABC transporter superfamily
CELL2_04410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_04415	COG0601	transmembrane transport
CELL2_04435	COG1312	Catalyzes the dehydration of D-mannonate
CELL2_04440	COG0246	Mannitol dehydrogenase
CELL2_04450	COG0800	Aldolase
CELL2_04455	COG1414	Transcriptional regulator
CELL2_04460	COG1904	glucuronate isomerase
CELL2_04475	COG3693	PFAM glycoside hydrolase, family 10
CELL2_04480	COG0601	transmembrane transport
CELL2_04485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_04490	COG0444	Belongs to the ABC transporter superfamily
CELL2_04495	COG4608	Belongs to the ABC transporter superfamily
CELL2_04500	COG0747	negative chemotaxis
CELL2_04505	COG3661	Belongs to the glycosyl hydrolase 67 family
CELL2_04525	COG1918	ferrous iron import across plasma membrane
CELL2_04525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CELL2_04535	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CELL2_04560	COG1132	(ABC) transporter
CELL2_04565	COG0006	proline dipeptidase activity
CELL2_04570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CELL2_04570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CELL2_04575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CELL2_04580	COG1469	GTP cyclohydrolase I activity
CELL2_04585	COG0720	synthase
CELL2_04590	COG2199	diguanylate cyclase activity
CELL2_04590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CELL2_04630	COG0601	transmembrane transport
CELL2_04640	COG0444	Belongs to the ABC transporter superfamily
CELL2_04645	COG4608	Belongs to the ABC transporter superfamily
CELL2_04680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CELL2_04685	COG1993	acr, cog1993
CELL2_04690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CELL2_04695	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_04700	COG1013	pyruvate-flavodoxin oxidoreductase activity
CELL2_04705	COG0674	pyruvate-flavodoxin oxidoreductase activity
CELL2_04710	COG1144	Oxidoreductase
CELL2_04715	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CELL2_04720	COG0840	transmembrane signaling receptor activity
CELL2_04750	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CELL2_04760	COG4948	Mandelate Racemase Muconate Lactonizing
CELL2_04770	COG0737	Belongs to the 5'-nucleotidase family
CELL2_04780	COG0622	Phosphoesterase
CELL2_04785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CELL2_04790	COG1278	Cold shock
CELL2_04800	COG0432	Pfam Uncharacterised protein family UPF0047
CELL2_04810	COG2894	cell division
CELL2_04815	COG1067	ATP-dependent peptidase activity
CELL2_04820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CELL2_04825	COG0039	L-malate dehydrogenase activity
CELL2_04855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CELL2_04860	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CELL2_04865	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CELL2_04870	COG2137	regulation of response to DNA damage stimulus
CELL2_04875	COG1418	mRNA catabolic process
CELL2_04900	COG1175	transmembrane transport
CELL2_04905	COG0395	ABC-type sugar transport system, permease component
CELL2_04930	COG3459	Glycosyltransferase 36 associated
CELL2_04935	COG2723	6-phospho-beta-galactosidase activity
CELL2_04940	COG1653	transport
CELL2_04955	COG1940	carbohydrate kinase activity
CELL2_04965	COG1523	belongs to the glycosyl hydrolase 13 family
CELL2_04970	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CELL2_04990	COG0366	Alpha amylase catalytic
CELL2_04995	COG2182	Extracellular solute-binding protein
CELL2_05000	COG1175	transmembrane transport
CELL2_05010	COG0366	Alpha amylase catalytic
CELL2_05025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_05030	COG4608	Belongs to the ABC transporter superfamily
CELL2_05040	COG1486	melibiose metabolic process
CELL2_05045	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CELL2_05060	COG3706	GGDEF domain
CELL2_05065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CELL2_05065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CELL2_05075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CELL2_05075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CELL2_05080	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CELL2_05090	COG0330	HflC and HflK could
CELL2_05095	COG0330	HflC and HflK could
CELL2_05100	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
CELL2_05105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CELL2_05105	COG0519	Catalyzes the synthesis of GMP from XMP
CELL2_05115	COG2059	Chromate
CELL2_05120	COG0525	valine-tRNA ligase activity
CELL2_05145	COG1353	crispr-associated protein
CELL2_05155	COG1337	RAMP superfamily
CELL2_05180	COG0484	heat shock protein binding
CELL2_05225	COG1518	maintenance of DNA repeat elements
CELL2_05230	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CELL2_05275	COG0640	Transcriptional regulator
CELL2_05290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CELL2_05295	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CELL2_05305	COG0165	Argininosuccinate lyase
CELL2_05325	COG0195	Participates in both transcription termination and antitermination
CELL2_05330	COG0735	belongs to the Fur family
CELL2_05355	COG1461	Dihydroxyacetone kinase
CELL2_05370	COG1722	exodeoxyribonuclease VII activity
CELL2_05390	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CELL2_05405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CELL2_05410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CELL2_05415	COG0556	nucleotide-excision repair
CELL2_05445	COG3426	butyrate kinase activity
CELL2_05450	COG0280	phosphate acetyltransferase
CELL2_05455	COG3426	butyrate kinase activity
CELL2_05465	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CELL2_05470	COG0667	Aldo Keto reductase
CELL2_05475	COG0647	UMP catabolic process
CELL2_05480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CELL2_05485	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CELL2_05500	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CELL2_05505	COG0305	Participates in initiation and elongation during chromosome replication
CELL2_05515	COG0704	Plays a role in the regulation of phosphate uptake
CELL2_05530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CELL2_05535	COG2255	four-way junction helicase activity
CELL2_05560	COG1394	ATPase activity, coupled to movement of substances
CELL2_05565	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CELL2_05570	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CELL2_05595	COG1269	ATP hydrolysis coupled proton transport
CELL2_05620	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_05625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CELL2_05640	COG2153	protein acetylation
CELL2_05655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CELL2_05660	COG1162	GTPase activity
CELL2_05680	COG1739	Uncharacterized protein family UPF0029
CELL2_05700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CELL2_05710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CELL2_05720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CELL2_05735	COG1368	sulfuric ester hydrolase activity
CELL2_05755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CELL2_05765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CELL2_05785	COG0301	tRNA thio-modification
CELL2_05810	COG0194	GDP metabolic process
CELL2_05815	COG1758	RNA polymerase activity
CELL2_05820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CELL2_05825	COG1376	ErfK ybiS ycfS ynhG family protein
CELL2_05830	COG1185	polyribonucleotide nucleotidyltransferase activity
CELL2_05840	COG1278	Cold shock
CELL2_05845	COG3437	response regulator, receiver
CELL2_05905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CELL2_05925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CELL2_05935	COG2813	Specifically methylates the guanine in position
CELL2_05940	COG1122	ATPase activity
CELL2_05945	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CELL2_05950	COG0242	peptide deformylase activity
CELL2_05965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CELL2_05970	COG0268	Binds directly to 16S ribosomal RNA
CELL2_05980	COG0745	RESPONSE REGULATOR receiver
CELL2_05985	COG5002	protein histidine kinase activity
CELL2_06000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CELL2_06015	COG1713	HD superfamily hydrolase involved in NAD metabolism
CELL2_06035	COG0157	Belongs to the NadC ModD family
CELL2_06050	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CELL2_06050	COG0540	Belongs to the ATCase OTCase family
CELL2_06055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CELL2_06065	COG0543	2 iron, 2 sulfur cluster binding
CELL2_06070	COG4555	ABC transporter
CELL2_06090	COG0420	3'-5' exonuclease activity
CELL2_06100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CELL2_06105	COG0802	atpase or kinase
CELL2_06120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CELL2_06125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CELL2_06155	COG0481	GTPase activity
CELL2_06165	COG0584	glycerophosphoryl diester phosphodiesterase
CELL2_06175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CELL2_06175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CELL2_06180	COG1406	Chemotaxis phosphatase CheX
CELL2_06195	COG0356	it plays a direct role in the translocation of protons across the membrane
CELL2_06200	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CELL2_06205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CELL2_06210	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CELL2_06215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CELL2_06220	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CELL2_06225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CELL2_06230	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CELL2_06235	COG1307	EDD domain protein, DegV family
CELL2_06240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CELL2_06245	COG1530	ribonuclease E activity
CELL2_06250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CELL2_06255	COG0528	UMP kinase activity
CELL2_06260	COG0477	Major facilitator Superfamily
CELL2_06265	COG1827	regulation of RNA biosynthetic process
CELL2_06270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELL2_06285	COG1595	DNA-templated transcription, initiation
CELL2_06290	COG3457	Alanine racemase
CELL2_06295	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CELL2_06300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CELL2_06305	COG3706	GGDEF domain
CELL2_06310	COG0489	protein tyrosine kinase activity
CELL2_06315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CELL2_06320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CELL2_06325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CELL2_06350	COG2379	hydroxypyruvate reductase
CELL2_06355	COG1040	competence protein
CELL2_06385	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CELL2_06390	COG0653	protein targeting
CELL2_06400	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CELL2_06410	COG0101	tRNA pseudouridine synthase activity
CELL2_06420	COG0681	Belongs to the peptidase S26 family
CELL2_06425	COG0335	large ribosomal subunit rRNA binding
CELL2_06430	COG4752	Belongs to the RNA methyltransferase TrmD family
CELL2_06435	COG0336	Belongs to the RNA methyltransferase TrmD family
CELL2_06440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CELL2_06445	COG1837	Belongs to the UPF0109 family
CELL2_06450	COG0228	four-way junction DNA binding
CELL2_06455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CELL2_06460	COG1254	Belongs to the acylphosphatase family
CELL2_06485	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CELL2_06495	COG2003	Belongs to the UPF0758 family
CELL2_06500	COG0424	maF-like protein
CELL2_06515	COG1477	protein flavinylation
CELL2_06525	COG2078	PFAM AMMECR1 domain protein
CELL2_06530	COG3872	metal-dependent enzyme
CELL2_06535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CELL2_06540	COG1086	Polysaccharide biosynthesis protein
CELL2_06545	COG1078	dGTPase activity
CELL2_06550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CELL2_06550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CELL2_06555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CELL2_06565	COG4786	Flagellar basal body rod
CELL2_06580	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CELL2_06585	COG1706	bacterial-type flagellum-dependent cell motility
CELL2_06595	COG1032	radical SAM domain protein
CELL2_06615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CELL2_06620	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CELL2_06625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CELL2_06635	COG2171	N-acyltransferase activity
CELL2_06645	COG0019	diaminopimelate decarboxylase activity
CELL2_06650	COG1473	amidohydrolase
CELL2_06665	COG1323	Belongs to the UPF0348 family
CELL2_06670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CELL2_06670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CELL2_06675	COG2738	Putative neutral zinc metallopeptidase
CELL2_06690	COG1480	7TM receptor with intracellular HD hydrolase
CELL2_06695	COG1702	phosphate starvation-inducible protein PhoH
CELL2_06705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CELL2_06710	COG0049	tRNA binding
CELL2_06715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CELL2_06720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CELL2_06725	COG0051	transcription antitermination factor activity, RNA binding
CELL2_06730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CELL2_06735	COG0088	Forms part of the polypeptide exit tunnel
CELL2_06740	COG0089	rRNA binding
CELL2_06745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CELL2_06750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CELL2_06755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CELL2_06760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CELL2_06765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CELL2_06770	COG0255	Belongs to the universal ribosomal protein uL29 family
CELL2_06775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CELL2_06780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CELL2_06785	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CELL2_06795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CELL2_06800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CELL2_06805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CELL2_06810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CELL2_06815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CELL2_06820	COG1841	ribosomal large subunit assembly
CELL2_06825	COG0200	Binds to the 23S rRNA
CELL2_06830	COG0201	protein transport
CELL2_06835	COG0563	adenylate kinase activity
CELL2_06845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CELL2_06850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CELL2_06855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CELL2_06860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CELL2_06865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CELL2_06870	COG0202	RNA polymerase activity
CELL2_06875	COG0203	ribosomal protein L17
CELL2_06880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CELL2_06885	COG1940	carbohydrate kinase activity
CELL2_06890	COG1307	EDD domain protein, DegV family
CELL2_06900	COG3437	response regulator, receiver
CELL2_06905	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CELL2_06910	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CELL2_06920	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CELL2_06930	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CELL2_06935	COG0706	membrane insertase activity
CELL2_06960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CELL2_06965	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CELL2_06970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CELL2_06980	COG0358	DNA primase activity
CELL2_06985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CELL2_06990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CELL2_07005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CELL2_07015	COG0539	negative regulation of cytoplasmic translation
CELL2_07020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CELL2_07030	COG1366	Belongs to the anti-sigma-factor antagonist family
CELL2_07040	COG2050	protein possibly involved in aromatic compounds catabolism
CELL2_07040	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CELL2_07050	COG1543	Belongs to the glycosyl hydrolase 57 family
CELL2_07085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CELL2_07095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CELL2_07100	COG0840	transmembrane signaling receptor activity
CELL2_07105	COG0840	transmembrane signaling receptor activity
CELL2_07110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CELL2_07125	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CELL2_07140	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CELL2_07150	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CELL2_07155	COG1213	nucleotidyl transferase
CELL2_07155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CELL2_07165	COG0719	Fe-S assembly protein
CELL2_07170	COG0483	inositol monophosphate 1-phosphatase activity
CELL2_07175	COG1621	beta-fructofuranosidase activity
CELL2_07200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELL2_07205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CELL2_07210	COG0233	cytoplasmic translational termination
CELL2_07225	COG0575	Belongs to the CDS family
CELL2_07240	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CELL2_07245	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CELL2_07275	COG0742	ribosomal rna small subunit methyltransferase
CELL2_07280	COG0237	dephospho-CoA kinase activity
CELL2_07290	COG0166	Belongs to the GPI family
CELL2_07295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CELL2_07300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CELL2_07320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CELL2_07325	COG1177	transmembrane transport
CELL2_07330	COG1176	ABC-type spermidine putrescine transport system, permease component I
CELL2_07335	COG3842	ATPase activity
CELL2_07340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CELL2_07345	COG0406	alpha-ribazole phosphatase activity
CELL2_07355	COG0822	iron-sulfur transferase activity
CELL2_07360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CELL2_07365	COG0719	Fe-S assembly protein
CELL2_07365	COG1372	Participates in initiation and elongation during chromosome replication
CELL2_07370	COG0719	Fe-S assembly protein
CELL2_07375	COG0396	ATPase activity
CELL2_07385	COG1677	Flagellar hook-basal body complex protein FliE
CELL2_07395	COG1815	bacterial-type flagellum-dependent cell motility
CELL2_07400	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CELL2_07410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CELL2_07415	COG0745	RESPONSE REGULATOR receiver
CELL2_07420	COG3852	Histidine kinase
CELL2_07445	COG0517	IMP dehydrogenase activity
CELL2_07445	COG0516	GMP reductase activity
CELL2_07460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CELL2_07465	COG2267	carboxylic ester hydrolase activity
CELL2_07470	COG0628	permease
CELL2_07480	COG0516	GMP reductase activity
CELL2_07480	COG0517	IMP dehydrogenase activity
CELL2_07485	COG0612	Peptidase, M16
CELL2_07490	COG1185	polyribonucleotide nucleotidyltransferase activity
CELL2_07495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CELL2_07570	COG1598	PFAM Uncharacterised protein family UPF0150
CELL2_07580	COG1598	PFAM Uncharacterised protein family UPF0150
CELL2_07615	COG4555	ABC transporter
CELL2_07635	COG0667	Aldo Keto reductase
CELL2_07645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELL2_07660	COG0662	Cupin 2, conserved barrel domain protein
CELL2_07665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CELL2_07690	COG1193	negative regulation of DNA recombination
CELL2_07700	COG3842	ATPase activity
CELL2_07720	COG0154	amidase activity
CELL2_07735	COG0626	cystathionine gamma-synthase activity
CELL2_07740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CELL2_07770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CELL2_07785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CELL2_07790	COG0704	Plays a role in the regulation of phosphate uptake
CELL2_07795	COG0745	RESPONSE REGULATOR receiver
CELL2_07810	COG1132	(ABC) transporter
CELL2_07815	COG0436	Aminotransferase
CELL2_07820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CELL2_07825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CELL2_07825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CELL2_07840	COG0151	Belongs to the GarS family
CELL2_07845	COG0138	bifunctional purine biosynthesis protein purh
CELL2_07850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CELL2_07855	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CELL2_07860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CELL2_07865	COG0047	phosphoribosylformylglycinamidine synthase activity
CELL2_07870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CELL2_07905	COG0210	DNA helicase
CELL2_07930	COG3842	ATPase activity
CELL2_07935	COG0383	alpha-mannosidase activity
CELL2_07940	COG0438	transferase activity, transferring glycosyl groups
CELL2_07945	COG0463	Glycosyl transferase, family 2
CELL2_07965	COG0747	negative chemotaxis
CELL2_07970	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CELL2_07975	COG1940	carbohydrate kinase activity
CELL2_07980	COG4166	transmembrane transport
CELL2_07995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_08000	COG0444	Belongs to the ABC transporter superfamily
CELL2_08005	COG4608	Belongs to the ABC transporter superfamily
CELL2_08010	COG1609	Transcriptional regulator
CELL2_08020	COG0649	NAD binding
CELL2_08025	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CELL2_08025	COG0649	NAD binding
CELL2_08030	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CELL2_08040	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CELL2_08045	COG0651	ATP synthesis coupled electron transport
CELL2_08055	COG2111	Na H antiporter
CELL2_08055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CELL2_08070	COG2212	antiporter activity
CELL2_08075	COG1863	multisubunit Na H antiporter MnhE subunit
CELL2_08095	COG0395	ABC-type sugar transport system, permease component
CELL2_08110	COG0444	Belongs to the ABC transporter superfamily
CELL2_08115	COG3250	beta-galactosidase activity
CELL2_08120	COG3345	alpha-galactosidase
CELL2_08125	COG1085	galactose-1-phosphate uridylyltransferase
CELL2_08130	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CELL2_08145	COG2203	Gaf domain
CELL2_08145	COG2199	diguanylate cyclase activity
CELL2_08155	COG0628	permease
CELL2_08165	COG1803	Methylglyoxal synthase
CELL2_08175	COG0667	Aldo Keto reductase
CELL2_08180	COG1196	nuclear chromosome segregation
CELL2_08185	COG0494	nUDIX hydrolase
CELL2_08195	COG1516	flagellar protein fliS
CELL2_08200	COG0456	acetyltransferase
CELL2_08205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CELL2_08210	COG1151	hydroxylamine reductase activity
CELL2_08225	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_08230	COG0058	SHG alpha-glucan phosphorylase activity
CELL2_08240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CELL2_08245	COG1013	pyruvate-flavodoxin oxidoreductase activity
CELL2_08260	COG2199	diguanylate cyclase activity
CELL2_08265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CELL2_08270	COG2239	Acts as a magnesium transporter
CELL2_08285	COG0010	Belongs to the arginase family
CELL2_08300	COG1983	PspC domain protein
CELL2_08305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CELL2_08310	COG0363	glucosamine-6-phosphate deaminase activity
CELL2_08315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_08320	COG0444	Belongs to the ABC transporter superfamily
CELL2_08325	COG4608	Belongs to the ABC transporter superfamily
CELL2_08330	COG0747	negative chemotaxis
CELL2_08350	COG0785	Cytochrome C biogenesis protein
CELL2_08360	COG0410	ABC transporter
CELL2_08365	COG0411	ABC transporter
CELL2_08375	COG0559	Belongs to the binding-protein-dependent transport system permease family
CELL2_08400	COG0714	Associated with various cellular activities
CELL2_08405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CELL2_08410	COG0280	phosphate acetyltransferase
CELL2_08415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CELL2_08445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CELL2_08455	COG1175	transmembrane transport
CELL2_08460	COG1653	transport
CELL2_08550	COG0622	Phosphoesterase
CELL2_08570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CELL2_08575	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CELL2_08580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CELL2_08585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CELL2_08610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CELL2_08620	COG0569	domain protein
CELL2_08635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELL2_08635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELL2_08640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CELL2_08645	COG1371	PFAM Archease protein family (DUF101 UPF0211)
CELL2_08655	COG1366	Belongs to the anti-sigma-factor antagonist family
CELL2_08660	COG0698	ribose 5-phosphate isomerase
CELL2_08700	COG1070	Carbohydrate kinase
CELL2_08710	COG4952	isomerase
CELL2_08720	COG1349	DNA-binding transcription factor activity
CELL2_08725	COG1486	melibiose metabolic process
CELL2_08750	COG3250	beta-galactosidase activity
CELL2_08770	COG2359	stage V sporulation protein S
CELL2_08780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CELL2_08785	COG1324	tolerance protein
CELL2_08795	COG1137	ATPase activity
CELL2_08805	COG1555	photosystem II stabilization
CELL2_08805	COG1596	polysaccharide export
CELL2_08840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CELL2_08845	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CELL2_08850	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CELL2_08855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CELL2_08865	COG0131	Imidazoleglycerol-phosphate dehydratase
CELL2_08870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CELL2_08875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CELL2_08880	COG0107	imidazoleglycerol-phosphate synthase activity
CELL2_08885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CELL2_08885	COG0140	phosphoribosyl-ATP diphosphatase activity
CELL2_08890	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CELL2_08895	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CELL2_08895	COG0662	Cupin 2, conserved barrel domain protein
CELL2_08925	COG1131	(ABC) transporter
CELL2_08950	COG2814	Major facilitator Superfamily
CELL2_08975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CELL2_09015	COG0656	L-ascorbic acid biosynthetic process
CELL2_09025	COG0667	Aldo Keto reductase
CELL2_09030	COG2207	Transcriptional regulator
CELL2_09040	COG0640	Transcriptional regulator
CELL2_09045	COG1691	(AIR) carboxylase
CELL2_09060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CELL2_09065	COG1193	negative regulation of DNA recombination
CELL2_09070	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CELL2_09075	COG1704	LemA family
CELL2_09080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CELL2_09095	COG1869	D-ribose catabolic process
CELL2_09100	COG1129	ABC transporter
CELL2_09115	COG1879	ABC-type sugar transport system periplasmic component
CELL2_09150	COG0174	glutamine synthetase
CELL2_09170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CELL2_09185	COG0402	S-adenosylhomocysteine deaminase activity
CELL2_09190	COG0517	IMP dehydrogenase activity
CELL2_09190	COG0516	GMP reductase activity
CELL2_09195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CELL2_09215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CELL2_09220	COG3864	Putative metallopeptidase domain
CELL2_09230	COG1141	Ferredoxin