TO73_0868 f9e29e4d7e943fec6ec080ee45187067 230 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 230 36.955 T 11-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TO73_0868 f9e29e4d7e943fec6ec080ee45187067 230 Pfam PF02654 Cobalamin-5-phosphate synthase 7 219 5.3E-44 T 11-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TO73_1592 49e0b957dec8a3bb7f3bbfe3110f4048 221 Pfam PF01813 ATP synthase subunit D 10 197 1.3E-51 T 11-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1592 49e0b957dec8a3bb7f3bbfe3110f4048 221 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 1 203 23.768 T 11-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1592 49e0b957dec8a3bb7f3bbfe3110f4048 221 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 1 202 7.8E-43 T 11-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 196 212 - T 11-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 196 212 2.4E-5 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 TIGRFAM TIGR01083 nth: endonuclease III 13 203 7.3E-81 T 11-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 Hamap MF_00942 Endonuclease III [nth]. 9 217 38.35 T 11-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 SUPERFAMILY SSF48150 12 216 1.26E-74 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 Gene3D G3DSA:1.10.1670.10 20 212 3.9E-78 T 11-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 ProSitePatterns PS01155 Endonuclease III family signature. 111 140 - T 11-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 Gene3D G3DSA:1.10.340.30 30 141 3.9E-78 T 11-10-2018 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 SMART SM00525 195 215 2.2E-6 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 PIRSF PIRSF001435 7 217 4.4E-52 T 11-10-2018 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 SMART SM00478 47 194 1.0E-57 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TO73_1900 68f2e7c8579a77bf8d294ca6335d96f4 217 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 43 177 6.5E-24 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 Pfam PF02817 e3 binding domain 142 177 9.1E-13 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 SUPERFAMILY SSF51230 1 91 1.44E-26 T 11-10-2018 IPR011053 Single hybrid motif TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 SUPERFAMILY SSF52777 211 452 1.38E-83 T 11-10-2018 TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 Gene3D G3DSA:3.30.559.10 213 452 3.5E-85 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 Gene3D G3DSA:2.40.50.100 1 99 1.1E-26 T 11-10-2018 TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 223 452 1.4E-85 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 Pfam PF00364 Biotin-requiring enzyme 3 76 7.2E-17 T 11-10-2018 IPR000089 Biotin/lipoyl attachment TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 Gene3D G3DSA:4.10.320.10 142 182 2.2E-18 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TO73_0137 e4facd45b1c1c0b7f077e59a2e9e5945 454 SUPERFAMILY SSF47005 137 181 1.23E-10 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TO73_0057 e919f907a3a1217b6a3db8dbe788048e 362 SMART SM00382 126 251 0.0042 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0057 e919f907a3a1217b6a3db8dbe788048e 362 Gene3D G3DSA:3.40.50.300 106 359 7.4E-100 T 11-10-2018 TO73_0057 e919f907a3a1217b6a3db8dbe788048e 362 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 197 211 - T 11-10-2018 IPR001482 Type II/IV secretion system protein TO73_0057 e919f907a3a1217b6a3db8dbe788048e 362 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 7 348 7.4E-153 T 11-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 TO73_0057 e919f907a3a1217b6a3db8dbe788048e 362 SUPERFAMILY SSF52540 7 337 1.1E-68 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0057 e919f907a3a1217b6a3db8dbe788048e 362 Gene3D G3DSA:3.30.450.90 3 103 1.4E-35 T 11-10-2018 TO73_0057 e919f907a3a1217b6a3db8dbe788048e 362 Pfam PF00437 Type II/IV secretion system protein 16 272 9.1E-44 T 11-10-2018 IPR001482 Type II/IV secretion system protein TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 Gene3D G3DSA:3.40.50.880 1 187 1.4E-57 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 Pfam PF00117 Glutamine amidotransferase class-I 3 181 4.2E-41 T 11-10-2018 IPR017926 Glutamine amidotransferase TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 184 2.6E-66 T 11-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 195 503 4.2E-130 T 11-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 SUPERFAMILY SSF52317 1 183 2.95E-54 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 2.8E-8 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 160 173 2.8E-8 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 2.8E-8 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 Gene3D G3DSA:3.40.50.620 191 383 2.2E-63 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 5.8E-6 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 2 16 5.8E-6 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 5.8E-6 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 503 49.725 T 11-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 SUPERFAMILY SSF54810 383 503 9.42E-48 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 SUPERFAMILY SSF52402 180 424 1.28E-47 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 Gene3D G3DSA:3.30.300.10 384 503 3.0E-50 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 PRINTS PR00097 Anthranilate synthase component II signature 46 55 3.3E-6 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 PRINTS PR00097 Anthranilate synthase component II signature 73 84 3.3E-6 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 PRINTS PR00097 Anthranilate synthase component II signature 160 173 3.3E-6 T 11-10-2018 TO73_1806 a861a8ca0d5a47ffd15e81b510e5dc4d 503 Pfam PF00958 GMP synthase C terminal domain 413 502 3.2E-38 T 11-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TO73_0083 34e3e210cf0421a8c34d459719add037 184 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 183 8.3E-63 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TO73_0083 34e3e210cf0421a8c34d459719add037 184 Pfam PF00467 KOW motif 133 164 3.7E-10 T 11-10-2018 IPR005824 KOW TO73_0083 34e3e210cf0421a8c34d459719add037 184 SUPERFAMILY SSF82679 4 114 2.35E-40 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TO73_0083 34e3e210cf0421a8c34d459719add037 184 SMART SM00739 130 157 5.7E-8 T 11-10-2018 IPR005824 KOW TO73_0083 34e3e210cf0421a8c34d459719add037 184 SMART SM00738 2 116 1.7E-50 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TO73_0083 34e3e210cf0421a8c34d459719add037 184 PRINTS PR00338 Transcription termination factor NUSG signature 58 70 1.3E-21 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TO73_0083 34e3e210cf0421a8c34d459719add037 184 PRINTS PR00338 Transcription termination factor NUSG signature 160 176 1.3E-21 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TO73_0083 34e3e210cf0421a8c34d459719add037 184 PRINTS PR00338 Transcription termination factor NUSG signature 142 157 1.3E-21 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TO73_0083 34e3e210cf0421a8c34d459719add037 184 Gene3D G3DSA:3.30.70.940 2 120 7.2E-48 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TO73_0083 34e3e210cf0421a8c34d459719add037 184 ProSitePatterns PS01014 Transcription termination factor nusG signature. 167 176 - T 11-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site TO73_0083 34e3e210cf0421a8c34d459719add037 184 SUPERFAMILY SSF50104 113 183 2.24E-20 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily TO73_0083 34e3e210cf0421a8c34d459719add037 184 Pfam PF02357 Transcription termination factor nusG 4 113 1.3E-25 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TO73_0083 34e3e210cf0421a8c34d459719add037 184 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 184 26.218 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TO73_0083 34e3e210cf0421a8c34d459719add037 184 Gene3D G3DSA:2.30.30.30 124 183 4.5E-27 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 TO73_2254 ec242aeb4add223142a1adc35ca4dbd7 240 SUPERFAMILY SSF46626 104 236 5.22E-28 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_2254 ec242aeb4add223142a1adc35ca4dbd7 240 PRINTS PR00605 Class IC cytochrome C signature 166 177 9.2E-8 T 11-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TO73_2254 ec242aeb4add223142a1adc35ca4dbd7 240 PRINTS PR00605 Class IC cytochrome C signature 206 228 9.2E-8 T 11-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TO73_2254 ec242aeb4add223142a1adc35ca4dbd7 240 Gene3D G3DSA:1.10.760.10 124 234 3.0E-23 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_2254 ec242aeb4add223142a1adc35ca4dbd7 240 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 156 228 1.7E-18 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 SUPERFAMILY SSF52440 553 671 7.19E-49 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 Gene3D G3DSA:3.30.470.20 119 407 3.2E-120 T 11-10-2018 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 SUPERFAMILY SSF52440 1 127 3.17E-46 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 SUPERFAMILY SSF48108 402 550 2.35E-46 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 8.8E-68 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 872 7.0E-33 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 SUPERFAMILY SSF56059 669 931 1.06E-89 T 11-10-2018 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.7E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 3.7E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.7E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.7E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 386 404 3.7E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.7E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.7E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 835 842 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 4 956 0.0 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1015 12.32 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 Gene3D G3DSA:3.40.50.20 551 658 3.4E-47 T 11-10-2018 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 Gene3D G3DSA:1.10.1030.10 408 549 1.9E-41 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 Gene3D G3DSA:3.30.470.20 662 933 1.4E-101 T 11-10-2018 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 SUPERFAMILY SSF56059 128 407 9.72E-103 T 11-10-2018 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 SMART SM01096 423 543 3.8E-63 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 Gene3D G3DSA:3.40.50.20 1 116 7.7E-47 T 11-10-2018 TO73_1144 20b19b4fccf85e76e499ba500e9ceb60 1030 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 543 6.8E-39 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_2332 11addcca8f58683293a38d935d5fdc69 385 Gene3D G3DSA:3.20.20.105 1 371 6.8E-155 T 11-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TO73_2332 11addcca8f58683293a38d935d5fdc69 385 SUPERFAMILY SSF51713 3 365 4.58E-146 T 11-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TO73_2332 11addcca8f58683293a38d935d5fdc69 385 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 365 7.1E-145 T 11-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TO73_2332 11addcca8f58683293a38d935d5fdc69 385 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 365 54.051 T 11-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TO73_2332 11addcca8f58683293a38d935d5fdc69 385 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 362 3.6E-82 T 11-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TO73_2332 11addcca8f58683293a38d935d5fdc69 385 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 365 4.6E-139 T 11-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 Pfam PF14520 Helix-hairpin-helix domain 537 589 5.9E-8 T 11-10-2018 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 Gene3D G3DSA:4.10.860.10 191 236 6.6E-9 T 11-10-2018 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 Pfam PF02151 UvrB/uvrC motif 199 231 8.8E-12 T 11-10-2018 IPR001943 UVR domain GO:0005515 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 SUPERFAMILY SSF82771 15 94 4.45E-17 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 Gene3D G3DSA:3.40.1440.10 3 96 5.4E-29 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 Gene3D G3DSA:1.10.150.20 536 589 8.2E-16 T 11-10-2018 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 Pfam PF01541 GIY-YIG catalytic domain 17 87 7.5E-6 T 11-10-2018 IPR000305 GIY-YIG endonuclease TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 SMART SM00465 15 92 1.9E-17 T 11-10-2018 IPR000305 GIY-YIG endonuclease TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 8 568 1.1E-154 T 11-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 586 26.829 T 11-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 SMART SM00278 535 554 47.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 SMART SM00278 567 586 2.3 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 377 519 2.4E-41 T 11-10-2018 IPR001162 UvrC family homology region TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 Gene3D G3DSA:3.30.420.340 371 532 4.8E-46 T 11-10-2018 IPR038476 UvrC homology region 2 superfamily TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 SUPERFAMILY SSF46600 183 233 1.96E-13 T 11-10-2018 IPR036876 UVR domain superfamily TO73_1512 d5e58cfc214f9f94c2cbe32ea164444a 595 SUPERFAMILY SSF47781 501 589 8.26E-16 T 11-10-2018 IPR010994 RuvA domain 2-like TO73_1352 f1c54a40d14fca30b397e6a7a6a15bd6 64 SUPERFAMILY SSF143034 3 64 7.06E-19 T 11-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1352 f1c54a40d14fca30b397e6a7a6a15bd6 64 Gene3D G3DSA:2.40.50.530 1 64 4.2E-27 T 11-10-2018 TO73_1352 f1c54a40d14fca30b397e6a7a6a15bd6 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 15.011 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TO73_1352 f1c54a40d14fca30b397e6a7a6a15bd6 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 9.4E-9 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TO73_1352 f1c54a40d14fca30b397e6a7a6a15bd6 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 9.4E-9 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TO73_1352 f1c54a40d14fca30b397e6a7a6a15bd6 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 9.4E-9 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TO73_1352 f1c54a40d14fca30b397e6a7a6a15bd6 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 11-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1352 f1c54a40d14fca30b397e6a7a6a15bd6 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 3 64 9.0E-21 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TO73_1352 f1c54a40d14fca30b397e6a7a6a15bd6 64 Pfam PF01632 Ribosomal protein L35 2 62 5.0E-20 T 11-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0894 976f334457f612b270d198f2bb5c340f 298 Gene3D G3DSA:3.40.50.2300 123 249 3.1E-53 T 11-10-2018 TO73_0894 976f334457f612b270d198f2bb5c340f 298 Pfam PF13377 Periplasmic binding protein-like domain 131 287 5.0E-30 T 11-10-2018 TO73_0894 976f334457f612b270d198f2bb5c340f 298 SUPERFAMILY SSF53822 46 289 7.79E-52 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_0894 976f334457f612b270d198f2bb5c340f 298 Gene3D G3DSA:1.10.260.40 1 28 1.8E-5 T 11-10-2018 TO73_0894 976f334457f612b270d198f2bb5c340f 298 Gene3D G3DSA:3.40.50.2300 29 263 3.1E-53 T 11-10-2018 TO73_0405 72a48376030e05fcd722b93d778516de 118 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 118 7.1E-41 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0405 72a48376030e05fcd722b93d778516de 118 SUPERFAMILY SSF64263 1 117 1.14E-45 T 11-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0405 72a48376030e05fcd722b93d778516de 118 Gene3D G3DSA:3.90.1030.10 1 118 7.2E-51 T 11-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0405 72a48376030e05fcd722b93d778516de 118 Pfam PF01196 Ribosomal protein L17 20 117 2.8E-35 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0405 72a48376030e05fcd722b93d778516de 118 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 117 26.417 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1519 7a41216079df6bc5c2179b31cdc077e5 441 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 331 354 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 TO73_1519 7a41216079df6bc5c2179b31cdc077e5 441 Pfam PF01134 Glucose inhibited division protein A 1 361 1.2E-106 T 11-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TO73_1519 7a41216079df6bc5c2179b31cdc077e5 441 Gene3D G3DSA:3.50.50.60 284 438 3.8E-52 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1519 7a41216079df6bc5c2179b31cdc077e5 441 Gene3D G3DSA:3.50.50.60 1 180 1.6E-55 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1519 7a41216079df6bc5c2179b31cdc077e5 441 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 1 426 34.71 T 11-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 TO73_1519 7a41216079df6bc5c2179b31cdc077e5 441 SUPERFAMILY SSF51905 3 361 8.21E-22 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1519 7a41216079df6bc5c2179b31cdc077e5 441 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 1 424 2.8E-187 T 11-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 TO73_1865 43ea68fc13d3093c9b5da49e5f2b20b5 582 PIRSF PIRSF002741 1 571 4.9E-71 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TO73_1865 43ea68fc13d3093c9b5da49e5f2b20b5 582 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 478 1.6E-75 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain TO73_1865 43ea68fc13d3093c9b5da49e5f2b20b5 582 Gene3D G3DSA:3.40.190.10 14 321 2.7E-58 T 11-10-2018 TO73_1865 43ea68fc13d3093c9b5da49e5f2b20b5 582 SUPERFAMILY SSF53850 35 568 8.62E-104 T 11-10-2018 TO73_1865 43ea68fc13d3093c9b5da49e5f2b20b5 582 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 89 111 - T 11-10-2018 IPR023765 Solute-binding protein family 5, conserved site TO73_1865 43ea68fc13d3093c9b5da49e5f2b20b5 582 Gene3D G3DSA:3.10.105.10 323 546 1.9E-39 T 11-10-2018 TO73_0757 a080de3633b031e1bfe7471cbfe8df29 176 SUPERFAMILY SSF53335 4 150 7.59E-17 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_0757 a080de3633b031e1bfe7471cbfe8df29 176 Gene3D G3DSA:3.40.50.150 5 150 1.7E-17 T 11-10-2018 TO73_1584 415d086beebb1ae1330d7f8bf948ea5b 182 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 9 136 3.6E-51 T 11-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1584 415d086beebb1ae1330d7f8bf948ea5b 182 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 140 28.061 T 11-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1584 415d086beebb1ae1330d7f8bf948ea5b 182 Gene3D G3DSA:3.30.70.3270 26 182 2.8E-64 T 11-10-2018 TO73_1584 415d086beebb1ae1330d7f8bf948ea5b 182 SUPERFAMILY SSF54862 26 170 2.64E-29 T 11-10-2018 TO73_1584 415d086beebb1ae1330d7f8bf948ea5b 182 Pfam PF12838 4Fe-4S dicluster domain 52 112 4.0E-14 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_1584 415d086beebb1ae1330d7f8bf948ea5b 182 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 Pfam PF00203 Ribosomal protein S19 3 83 4.9E-38 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 PIRSF PIRSF002144 1 93 9.1E-35 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 SUPERFAMILY SSF54570 3 85 4.45E-37 T 11-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 Gene3D G3DSA:3.30.860.10 1 93 4.0E-45 T 11-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.0E-26 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.0E-26 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.0E-26 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 11-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 2.6E-46 T 11-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 TO73_0380 691c35a2d4f10c15230f66222304ab2b 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 26.129 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_1506 38de1015c68e0c9cf9282f8cda382551 598 SUPERFAMILY SSF50249 539 597 2.57E-12 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1506 38de1015c68e0c9cf9282f8cda382551 598 SUPERFAMILY SSF50249 170 537 2.68E-87 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1506 38de1015c68e0c9cf9282f8cda382551 598 SMART SM00955 223 496 3.5E-73 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TO73_1506 38de1015c68e0c9cf9282f8cda382551 598 Pfam PF00773 RNB domain 223 495 8.2E-48 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TO73_1506 38de1015c68e0c9cf9282f8cda382551 598 Gene3D G3DSA:2.40.50.140 539 598 2.3E-6 T 11-10-2018 TO73_1506 38de1015c68e0c9cf9282f8cda382551 598 Gene3D G3DSA:1.10.10.10 147 214 5.2E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2252 025876bde5452595380e9b7db647374f 398 SUPERFAMILY SSF53850 19 395 1.58E-74 T 11-10-2018 TO73_2252 025876bde5452595380e9b7db647374f 398 Pfam PF13416 Bacterial extracellular solute-binding protein 37 330 4.4E-35 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein TO73_2252 025876bde5452595380e9b7db647374f 398 Gene3D G3DSA:3.40.190.10 22 357 6.2E-84 T 11-10-2018 TO73_2252 025876bde5452595380e9b7db647374f 398 Gene3D G3DSA:3.40.190.10 134 393 6.2E-84 T 11-10-2018 TO73_0640 a5048407de8127b5cdf169c2d10df725 317 Gene3D G3DSA:1.10.10.10 262 317 1.9E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0640 a5048407de8127b5cdf169c2d10df725 317 Pfam PF00753 Metallo-beta-lactamase superfamily 21 233 1.8E-26 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_0640 a5048407de8127b5cdf169c2d10df725 317 Gene3D G3DSA:3.60.15.10 1 261 4.2E-83 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_0640 a5048407de8127b5cdf169c2d10df725 317 SMART SM00849 21 233 3.2E-31 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_0640 a5048407de8127b5cdf169c2d10df725 317 SUPERFAMILY SSF56281 2 305 2.3E-62 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_1637 32fe9556134a411208d5163e722ef5ef 171 Pfam PF04264 YceI-like domain 38 168 1.4E-8 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TO73_1637 32fe9556134a411208d5163e722ef5ef 171 SMART SM00867 19 170 0.004 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TO73_1637 32fe9556134a411208d5163e722ef5ef 171 SUPERFAMILY SSF101874 26 170 2.35E-17 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TO73_1637 32fe9556134a411208d5163e722ef5ef 171 Gene3D G3DSA:2.40.128.110 25 171 2.2E-16 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TO73_1389 ba731c933f735f5568fcb8a50553c146 371 Gene3D G3DSA:3.60.21.10 1 260 7.4E-59 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like TO73_1389 ba731c933f735f5568fcb8a50553c146 371 Pfam PF00149 Calcineurin-like phosphoesterase 2 89 1.2E-11 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TO73_1389 ba731c933f735f5568fcb8a50553c146 371 SUPERFAMILY SSF56300 2 310 1.3E-46 T 11-10-2018 TO73_1389 ba731c933f735f5568fcb8a50553c146 371 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 2 235 4.4E-39 T 11-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 TO73_0149 9dbae233fedf3ea166830662ed1c8904 369 SUPERFAMILY SSF50182 193 255 2.13E-13 T 11-10-2018 IPR010920 LSM domain superfamily TO73_0149 9dbae233fedf3ea166830662ed1c8904 369 Gene3D G3DSA:3.30.70.100 260 349 1.7E-31 T 11-10-2018 TO73_0149 9dbae233fedf3ea166830662ed1c8904 369 SUPERFAMILY SSF82861 106 192 8.76E-12 T 11-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TO73_0149 9dbae233fedf3ea166830662ed1c8904 369 Pfam PF00924 Mechanosensitive ion channel 152 351 5.7E-44 T 11-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TO73_0149 9dbae233fedf3ea166830662ed1c8904 369 Gene3D G3DSA:2.30.30.60 209 258 1.2E-16 T 11-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TO73_0149 9dbae233fedf3ea166830662ed1c8904 369 SUPERFAMILY SSF82689 258 362 6.67E-25 T 11-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 Pfam PF04539 Sigma-70 region 3 282 360 5.7E-26 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 Pfam PF00140 Sigma-70 factor, region 1.2 95 128 5.5E-16 T 11-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 199 425 2.3E-39 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 Gene3D G3DSA:1.10.10.10 355 436 1.6E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 SUPERFAMILY SSF88659 276 352 1.57E-19 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 199 438 1.8E-115 T 11-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 SUPERFAMILY SSF88659 335 427 7.85E-29 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 Pfam PF04542 Sigma-70 region 2 203 272 4.4E-20 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 SUPERFAMILY SSF88946 92 273 3.27E-57 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 Gene3D G3DSA:1.20.120.1810 90 272 3.4E-81 T 11-10-2018 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 Pfam PF04545 Sigma-70, region 4 373 425 2.6E-18 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 398 424 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 2 439 33.971 T 11-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 Gene3D G3DSA:1.10.10.10 276 354 7.7E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 PRINTS PR00046 Major sigma-70 factor signature 227 240 2.0E-27 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 PRINTS PR00046 Major sigma-70 factor signature 377 389 2.0E-27 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 PRINTS PR00046 Major sigma-70 factor signature 413 424 2.0E-27 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 PRINTS PR00046 Major sigma-70 factor signature 398 413 2.0E-27 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TO73_1771 5fb834bbb9ad6366007b7083cb098a64 439 PRINTS PR00046 Major sigma-70 factor signature 251 259 2.0E-27 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 SUPERFAMILY SSF55781 24 166 1.35E-18 T 11-10-2018 TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 SUPERFAMILY SSF55073 453 606 8.63E-46 T 11-10-2018 IPR029787 Nucleotide cyclase TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 Gene3D G3DSA:3.20.20.450 615 856 1.4E-76 T 11-10-2018 IPR035919 EAL domain superfamily TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 SUPERFAMILY SSF55781 293 447 1.64E-14 T 11-10-2018 TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 Gene3D G3DSA:3.30.450.40 276 441 2.0E-15 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 Pfam PF00990 Diguanylate cyclase, GGDEF domain 448 600 1.2E-40 T 11-10-2018 IPR000160 GGDEF domain TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 Gene3D G3DSA:3.30.70.270 447 614 5.6E-51 T 11-10-2018 TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 SMART SM00267 437 604 1.9E-63 T 11-10-2018 IPR000160 GGDEF domain TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 SMART SM00065 19 175 1.7E-10 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 SMART SM00065 294 445 0.035 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 Gene3D G3DSA:3.30.450.40 22 176 3.9E-19 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 Pfam PF13185 GAF domain 292 435 7.8E-8 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 SMART SM00052 614 857 1.5E-76 T 11-10-2018 IPR001633 EAL domain TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 Pfam PF00563 EAL domain 620 852 2.7E-58 T 11-10-2018 IPR001633 EAL domain TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 Pfam PF01590 GAF domain 25 164 7.4E-11 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 SUPERFAMILY SSF141868 627 855 9.15E-65 T 11-10-2018 IPR035919 EAL domain superfamily TO73_1713 36365370201ceee41a0bf8c5f0b6cd85 857 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 446 602 1.9E-35 T 11-10-2018 IPR000160 GGDEF domain TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 PIRSF PIRSF000447 1 408 1.8E-197 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 SUPERFAMILY SSF53901 1 249 1.41E-79 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 366 4.5E-42 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 406 7.8E-193 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 Gene3D G3DSA:3.40.47.10 254 397 3.4E-59 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 SUPERFAMILY SSF53901 212 407 8.56E-75 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 1.4E-60 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 SMART SM00825 Beta-ketoacyl synthase 4 399 3.3E-16 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TO73_1551 4852a0a247cacb1b418674ae05aa1a45 408 Gene3D G3DSA:3.40.47.10 1 252 4.0E-93 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1735 1f46c931f450d257e5650e5ae97de61a 378 SMART SM00729 53 279 0.0077 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_1735 1f46c931f450d257e5650e5ae97de61a 378 PIRSF PIRSF004762 2 372 3.8E-93 T 11-10-2018 TO73_1735 1f46c931f450d257e5650e5ae97de61a 378 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 13 363 49.992 T 11-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TO73_1735 1f46c931f450d257e5650e5ae97de61a 378 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 49 360 3.6E-95 T 11-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 TO73_1735 1f46c931f450d257e5650e5ae97de61a 378 Pfam PF04055 Radical SAM superfamily 57 227 2.7E-13 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_1735 1f46c931f450d257e5650e5ae97de61a 378 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 14 360 8.3E-130 T 11-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TO73_1735 1f46c931f450d257e5650e5ae97de61a 378 Gene3D G3DSA:3.20.20.70 2 349 7.3E-45 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1735 1f46c931f450d257e5650e5ae97de61a 378 SUPERFAMILY SSF102114 13 353 7.32E-47 T 11-10-2018 TO73_0309 a676d52eb7ef11a82fad1ddfd2078147 362 SMART SM00922 144 239 3.4E-18 T 11-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TO73_0309 a676d52eb7ef11a82fad1ddfd2078147 362 Gene3D G3DSA:3.20.20.120 119 330 6.4E-67 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TO73_0309 a676d52eb7ef11a82fad1ddfd2078147 362 Pfam PF13378 Enolase C-terminal domain-like 147 310 4.3E-26 T 11-10-2018 IPR029065 Enolase C-terminal domain-like TO73_0309 a676d52eb7ef11a82fad1ddfd2078147 362 SUPERFAMILY SSF51604 131 343 1.44E-38 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TO73_0309 a676d52eb7ef11a82fad1ddfd2078147 362 SUPERFAMILY SSF54826 8 126 1.51E-18 T 11-10-2018 TO73_0309 a676d52eb7ef11a82fad1ddfd2078147 362 Gene3D G3DSA:3.30.390.10 7 118 6.4E-67 T 11-10-2018 IPR029017 Enolase-like, N-terminal TO73_1221 4dc5655c399fb4fee06dfa19528adf07 286 Gene3D G3DSA:1.10.150.170 108 208 1.3E-117 T 11-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TO73_1221 4dc5655c399fb4fee06dfa19528adf07 286 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 284 37.619 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TO73_1221 4dc5655c399fb4fee06dfa19528adf07 286 PIRSF PIRSF004486 1 285 8.2E-105 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TO73_1221 4dc5655c399fb4fee06dfa19528adf07 286 Pfam PF01795 MraW methylase family 5 283 1.2E-98 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TO73_1221 4dc5655c399fb4fee06dfa19528adf07 286 SUPERFAMILY SSF53335 7 283 1.44E-55 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1221 4dc5655c399fb4fee06dfa19528adf07 286 Gene3D G3DSA:3.40.50.150 7 282 1.3E-117 T 11-10-2018 TO73_1221 4dc5655c399fb4fee06dfa19528adf07 286 SUPERFAMILY SSF81799 110 207 3.4E-34 T 11-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TO73_1221 4dc5655c399fb4fee06dfa19528adf07 286 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 4 283 3.5E-96 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Gene3D G3DSA:3.20.20.20 358 650 4.9E-91 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 SUPERFAMILY SSF52242 745 873 9.94E-36 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 SUPERFAMILY SSF51717 369 637 3.53E-73 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 SUPERFAMILY SSF82282 40 411 2.09E-109 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 964 1183 7.9E-37 T 11-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Gene3D G3DSA:3.20.20.330 40 348 1.7E-94 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 PIRSF PIRSF000381 34 1185 0.0 T 11-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Pfam PF02607 B12 binding domain 665 738 2.9E-26 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Gene3D G3DSA:3.40.50.280 747 881 8.3E-42 T 11-10-2018 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Gene3D G3DSA:3.10.196.10 906 1183 1.5E-45 T 11-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 SUPERFAMILY SSF47644 659 743 2.22E-26 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 SMART SM01018 662 745 4.4E-41 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Pfam PF00809 Pterin binding enzyme 372 605 4.7E-47 T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Pfam PF02574 Homocysteine S-methyltransferase 50 337 2.9E-65 T 11-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Gene3D G3DSA:1.10.1240.10 654 742 3.5E-31 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Pfam PF02310 B12 binding domain 750 864 2.6E-19 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 TIGRFAM TIGR02082 metH: methionine synthase 48 1183 0.0 T 11-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 Gene3D G3DSA:1.10.288.10 920 978 1.5E-45 T 11-10-2018 TO73_1134 34aa31ea10e0b743e6faab956080fc39 1185 SUPERFAMILY SSF56507 898 1184 2.35E-79 T 11-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_0117 f628b8c520b34b1d5760d65ec9986b33 126 Gene3D G3DSA:3.40.50.1380 1 126 2.5E-55 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TO73_0117 f628b8c520b34b1d5760d65ec9986b33 126 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 2 121 32.498 T 11-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TO73_0117 f628b8c520b34b1d5760d65ec9986b33 126 PIRSF PIRSF006614 1 126 1.7E-52 T 11-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TO73_0117 f628b8c520b34b1d5760d65ec9986b33 126 Pfam PF02142 MGS-like domain 15 108 3.5E-18 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain TO73_0117 f628b8c520b34b1d5760d65ec9986b33 126 ProSitePatterns PS01335 Methylglyoxal synthase active site. 55 63 - T 11-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TO73_0117 f628b8c520b34b1d5760d65ec9986b33 126 SUPERFAMILY SSF52335 2 120 3.66E-48 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TO73_0117 f628b8c520b34b1d5760d65ec9986b33 126 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 3 120 1.8E-54 T 11-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TO73_0117 f628b8c520b34b1d5760d65ec9986b33 126 SMART SM00851 15 108 2.2E-24 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 Pfam PF17191 RecG wedge domain 103 255 7.8E-19 T 11-10-2018 IPR033454 RecG, wedge domain TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 Pfam PF00270 DEAD/DEAH box helicase 344 501 1.6E-16 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 Gene3D G3DSA:3.40.50.300 527 697 4.8E-56 T 11-10-2018 TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 SUPERFAMILY SSF50249 102 259 4.28E-37 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 SMART SM00487 338 529 1.9E-30 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 SUPERFAMILY SSF52540 522 721 1.25E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 SMART SM00490 573 657 3.3E-23 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 Gene3D G3DSA:2.40.50.140 130 226 7.3E-14 T 11-10-2018 TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 111 730 1.0E-213 T 11-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 SUPERFAMILY SSF52540 273 523 1.72E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 Gene3D G3DSA:3.40.50.300 295 519 1.5E-83 T 11-10-2018 TO73_1374 672f9fbdc65c6de0e4785a3950c5a4ab 767 Pfam PF00271 Helicase conserved C-terminal domain 547 657 3.7E-20 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_1699 2493dfc0cc2114abacb3a986e9b538a3 263 Gene3D G3DSA:3.40.30.10 123 260 5.4E-37 T 11-10-2018 TO73_1699 2493dfc0cc2114abacb3a986e9b538a3 263 SUPERFAMILY SSF52833 103 259 1.08E-37 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1699 2493dfc0cc2114abacb3a986e9b538a3 263 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 124 9.5E-8 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TO73_1699 2493dfc0cc2114abacb3a986e9b538a3 263 Pfam PF08534 Redoxin 130 250 2.3E-18 T 11-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 TO73_1946 6fdece7e38dd587c621aaf2ba2aed328 137 SUPERFAMILY SSF49764 27 134 3.49E-25 T 11-10-2018 IPR008978 HSP20-like chaperone TO73_1946 6fdece7e38dd587c621aaf2ba2aed328 137 Pfam PF00011 Hsp20/alpha crystallin family 39 134 5.1E-20 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TO73_1946 6fdece7e38dd587c621aaf2ba2aed328 137 Gene3D G3DSA:2.60.40.790 2 135 1.9E-26 T 11-10-2018 IPR008978 HSP20-like chaperone TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 Gene3D G3DSA:3.30.70.260 259 334 2.2E-30 T 11-10-2018 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 402 7.4E-123 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 Gene3D G3DSA:3.30.70.260 335 403 2.3E-22 T 11-10-2018 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 401 1.1E-102 T 11-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 SUPERFAMILY SSF55021 333 403 8.78E-19 T 11-10-2018 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 Gene3D G3DSA:3.40.1160.10 1 253 1.6E-85 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 Pfam PF00696 Amino acid kinase family 3 229 1.4E-51 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 PIRSF PIRSF000726 60 405 1.3E-107 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 PIRSF PIRSF000726 1 63 1.8E-19 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 11-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 Pfam PF13840 ACT domain 337 397 1.3E-9 T 11-10-2018 IPR027795 CASTOR, ACT domain TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 SUPERFAMILY SSF55021 249 327 9.16E-16 T 11-10-2018 TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 Pfam PF01842 ACT domain 266 322 1.8E-8 T 11-10-2018 IPR002912 ACT domain TO73_1769 52534b7d25e9c3883321cfcbff4a6b72 405 SUPERFAMILY SSF53633 4 240 5.24E-72 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_1462 430bfa60316756cab781c5b19a016871 359 Pfam PF13377 Periplasmic binding protein-like domain 209 349 5.1E-24 T 11-10-2018 TO73_1462 430bfa60316756cab781c5b19a016871 359 Gene3D G3DSA:3.40.50.2300 176 309 5.8E-73 T 11-10-2018 TO73_1462 430bfa60316756cab781c5b19a016871 359 SUPERFAMILY SSF47413 19 78 7.64E-19 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TO73_1462 430bfa60316756cab781c5b19a016871 359 SUPERFAMILY SSF53822 80 353 1.48E-43 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_1462 430bfa60316756cab781c5b19a016871 359 SMART SM00354 20 90 1.2E-26 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TO73_1462 430bfa60316756cab781c5b19a016871 359 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 67 4.5E-19 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TO73_1462 430bfa60316756cab781c5b19a016871 359 ProSitePatterns PS00356 LacI-type HTH domain signature. 23 41 - T 11-10-2018 TO73_1462 430bfa60316756cab781c5b19a016871 359 Gene3D G3DSA:3.40.50.2300 83 329 5.8E-73 T 11-10-2018 TO73_1462 430bfa60316756cab781c5b19a016871 359 Gene3D G3DSA:1.10.260.40 13 77 6.2E-24 T 11-10-2018 TO73_0135 33e9ba599a6243e758269cad65886cec 289 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 159 280 1.0E-40 T 11-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TO73_0135 33e9ba599a6243e758269cad65886cec 289 Gene3D G3DSA:1.10.1040.10 158 289 5.9E-31 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TO73_0135 33e9ba599a6243e758269cad65886cec 289 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 11-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 TO73_0135 33e9ba599a6243e758269cad65886cec 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 156 2.0E-41 T 11-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TO73_0135 33e9ba599a6243e758269cad65886cec 289 PIRSF PIRSF000103 1 288 4.0E-63 T 11-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TO73_0135 33e9ba599a6243e758269cad65886cec 289 SUPERFAMILY SSF48179 158 287 1.93E-28 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TO73_0135 33e9ba599a6243e758269cad65886cec 289 SUPERFAMILY SSF51735 3 157 4.54E-45 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0135 33e9ba599a6243e758269cad65886cec 289 Gene3D G3DSA:3.40.50.720 2 157 4.3E-57 T 11-10-2018 TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 Pfam PF03764 Elongation factor G, domain IV 445 561 1.1E-37 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 Gene3D G3DSA:3.30.70.240 567 637 3.8E-77 T 11-10-2018 TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 SUPERFAMILY SSF52540 2 267 1.41E-72 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 Gene3D G3DSA:3.30.70.870 371 446 3.1E-23 T 11-10-2018 TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 SMART SM00838 563 650 9.4E-31 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 SUPERFAMILY SSF50447 250 366 1.9E-20 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 Pfam PF00009 Elongation factor Tu GTP binding domain 2 267 1.3E-33 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 Pfam PF00679 Elongation factor G C-terminus 564 648 1.8E-23 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 SMART SM00889 446 561 3.1E-61 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 SUPERFAMILY SSF54980 564 653 7.67E-23 T 11-10-2018 IPR035647 EF-G domain III/V-like TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 SUPERFAMILY SSF54980 372 447 5.4E-19 T 11-10-2018 IPR035647 EF-G domain III/V-like TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 141 5.2E-13 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 SUPERFAMILY SSF54211 448 562 7.84E-41 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 Gene3D G3DSA:3.30.230.10 450 650 3.8E-77 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 Gene3D G3DSA:3.40.50.300 1 273 7.8E-75 T 11-10-2018 TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 Gene3D G3DSA:2.40.30.10 274 370 7.5E-21 T 11-10-2018 TO73_0467 7400599c831c19dbf337d77a5bc45eed 658 Pfam PF14492 Elongation Factor G, domain II 371 442 1.3E-23 T 11-10-2018 TO73_0886 62ff273b4b0f5a56dae50638e6d6f66d 260 SUPERFAMILY SSF110399 2 240 7.98E-73 T 11-10-2018 TO73_0886 62ff273b4b0f5a56dae50638e6d6f66d 260 Gene3D G3DSA:3.20.20.70 1 241 2.0E-107 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0886 62ff273b4b0f5a56dae50638e6d6f66d 260 Hamap MF_00443 Thiazole synthase [thiG]. 3 256 41.324 T 11-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TO73_0886 62ff273b4b0f5a56dae50638e6d6f66d 260 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 250 8.8E-99 T 11-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TO73_1736 f7925437d38f28494b86c470fb0b3248 259 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 46 59 - T 11-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TO73_1736 f7925437d38f28494b86c470fb0b3248 259 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 13 252 34.893 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TO73_1736 f7925437d38f28494b86c470fb0b3248 259 Gene3D G3DSA:3.20.20.70 1 257 1.2E-96 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1736 f7925437d38f28494b86c470fb0b3248 259 SUPERFAMILY SSF51366 4 239 2.64E-76 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TO73_1736 f7925437d38f28494b86c470fb0b3248 259 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 239 4.3E-71 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TO73_1736 f7925437d38f28494b86c470fb0b3248 259 Pfam PF00290 Tryptophan synthase alpha chain 7 238 4.2E-90 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TO73_2502 7d19f7fc1b3761d50c15a5696d5ddf50 78 SUPERFAMILY SSF46689 6 70 1.63E-20 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_2502 7d19f7fc1b3761d50c15a5696d5ddf50 78 Pfam PF04255 Protein of unknown function (DUF433) 10 65 3.9E-24 T 11-10-2018 IPR007367 Protein of unknown function DUF433 TO73_2502 7d19f7fc1b3761d50c15a5696d5ddf50 78 Gene3D G3DSA:1.10.10.10 9 76 3.9E-18 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0067 bdab5311f25e452f312a9d838ea13abd 262 Pfam PF13263 PHP-associated 206 233 1.3E-6 T 11-10-2018 TO73_0067 bdab5311f25e452f312a9d838ea13abd 262 Gene3D G3DSA:3.20.20.140 1 262 1.7E-81 T 11-10-2018 TO73_0067 bdab5311f25e452f312a9d838ea13abd 262 SUPERFAMILY SSF89550 1 250 8.63E-49 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TO73_0067 bdab5311f25e452f312a9d838ea13abd 262 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 1 232 4.2E-51 T 11-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 TO73_0067 bdab5311f25e452f312a9d838ea13abd 262 Pfam PF02811 PHP domain 1 188 1.2E-7 T 11-10-2018 IPR004013 PHP domain GO:0003824 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 SMART SM00926 249 303 1.7E-12 T 11-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 SUPERFAMILY SSF53706 247 661 2.62E-79 T 11-10-2018 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 SUPERFAMILY SSF54292 2 95 3.57E-20 T 11-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Pfam PF00384 Molybdopterin oxidoreductase 305 409 8.5E-6 T 11-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 119 131 - T 11-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 96 1.7E-12 T 11-10-2018 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Gene3D G3DSA:3.30.70.20 160 237 2.0E-7 T 11-10-2018 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Pfam PF01568 Molydopterin dinucleotide binding domain 706 760 4.6E-6 T 11-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 642 6.7E-143 T 11-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 141 1.1E-14 T 11-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Gene3D G3DSA:2.20.25.90 249 303 1.1E-14 T 11-10-2018 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 11-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 SUPERFAMILY SSF54862 97 244 7.11E-32 T 11-10-2018 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Gene3D G3DSA:3.10.20.740 1 144 4.7E-29 T 11-10-2018 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Gene3D G3DSA:3.40.228.10 378 481 1.0E-6 T 11-10-2018 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Gene3D G3DSA:3.40.50.740 571 685 3.8E-9 T 11-10-2018 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Gene3D G3DSA:3.40.50.740 310 377 1.0E-6 T 11-10-2018 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 SMART SM00929 104 144 2.7E-16 T 11-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 249 299 5.2E-9 T 11-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 SUPERFAMILY SSF50692 688 767 9.12E-38 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TO73_1582 28af18c2d69e75cbed588a827cfd1598 783 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 180 190 - T 11-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 140 156 - T 11-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 Gene3D G3DSA:3.30.360.10 143 316 6.0E-113 T 11-10-2018 TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 SUPERFAMILY SSF51735 2 159 3.45E-47 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 136 2.9E-30 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 SUPERFAMILY SSF55347 145 316 1.11E-37 T 11-10-2018 TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 SMART SM00859 3 137 2.1E-52 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 Gene3D G3DSA:3.40.50.720 3 334 6.0E-113 T 11-10-2018 TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 348 2.9E-117 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 154 319 8.0E-13 T 11-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_1325 d0360503fcca486c6c7c4a55d0ccc44e 348 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 342 40.258 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_2134 f0a661c2a7c2c3fce4d5e4583e73c85e 314 SUPERFAMILY SSF51735 104 267 6.08E-42 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_2134 f0a661c2a7c2c3fce4d5e4583e73c85e 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 22 81 2.3E-11 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TO73_2134 f0a661c2a7c2c3fce4d5e4583e73c85e 314 SUPERFAMILY SSF50129 3 134 1.08E-41 T 11-10-2018 IPR011032 GroES-like superfamily TO73_2134 f0a661c2a7c2c3fce4d5e4583e73c85e 314 SMART SM00829 5 312 9.5E-28 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TO73_2134 f0a661c2a7c2c3fce4d5e4583e73c85e 314 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 133 154 - T 11-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TO73_2134 f0a661c2a7c2c3fce4d5e4583e73c85e 314 Pfam PF00107 Zinc-binding dehydrogenase 144 245 2.2E-24 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TO73_2134 f0a661c2a7c2c3fce4d5e4583e73c85e 314 Gene3D G3DSA:3.40.50.720 116 258 1.1E-116 T 11-10-2018 TO73_2134 f0a661c2a7c2c3fce4d5e4583e73c85e 314 Gene3D G3DSA:3.90.180.10 5 311 1.1E-116 T 11-10-2018 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 SMART SM00359 275 358 5.5E-25 T 11-10-2018 IPR002478 PUA domain GO:0003723 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 Gene3D G3DSA:2.30.130.10 264 366 1.0E-34 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 PRINTS PR00474 Glutamate 5-kinase family signature 117 138 7.0E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 PRINTS PR00474 Glutamate 5-kinase family signature 44 58 7.0E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 PRINTS PR00474 Glutamate 5-kinase family signature 149 176 7.0E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 7.0E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 PRINTS PR00474 Glutamate 5-kinase family signature 77 105 7.0E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 Pfam PF01472 PUA domain 275 349 1.1E-23 T 11-10-2018 IPR002478 PUA domain GO:0003723 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 Gene3D G3DSA:3.40.1160.10 5 261 4.7E-83 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 Hamap MF_00456 Glutamate 5-kinase [proB]. 8 258 37.177 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 PIRSF PIRSF000729 5 367 4.2E-129 T 11-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 11-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 SUPERFAMILY SSF88697 274 364 4.03E-23 T 11-10-2018 IPR015947 PUA-like superfamily TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 TIGRFAM TIGR01027 proB: glutamate 5-kinase 8 364 1.2E-133 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 SUPERFAMILY SSF53633 8 255 9.43E-67 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_2358 ab103afc734a0ea313ea20be8dfa080e 369 Pfam PF00696 Amino acid kinase family 8 231 1.6E-40 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TO73_0435 badadec50c84ed1b748dd12675e5be97 82 SUPERFAMILY SSF89447 4 44 1.92E-11 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily TO73_0435 badadec50c84ed1b748dd12675e5be97 82 Gene3D G3DSA:2.10.260.10 5 43 1.7E-13 T 11-10-2018 TO73_0435 badadec50c84ed1b748dd12675e5be97 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 45 5.1E-12 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TO73_0435 badadec50c84ed1b748dd12675e5be97 82 SMART SM00966 5 50 1.2E-12 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TO73_0435 badadec50c84ed1b748dd12675e5be97 82 ProDom PD058861 TRANSCRIPTIONAL ABRB FAMILY REGULATOR AF0476 REGULATOR 5 31 0.005 T 11-10-2018 TO73_0435 badadec50c84ed1b748dd12675e5be97 82 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 45 3.3E-14 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TO73_0720 5bb9a45d635bbcd363a04b4c36b66c33 438 TIGRFAM TIGR00277 HDIG: HDIG domain 220 305 5.6E-17 T 11-10-2018 IPR006675 HDIG domain TO73_0720 5bb9a45d635bbcd363a04b4c36b66c33 438 SUPERFAMILY SSF81891 128 424 7.06E-45 T 11-10-2018 TO73_0720 5bb9a45d635bbcd363a04b4c36b66c33 438 SMART SM00471 225 358 3.8E-7 T 11-10-2018 IPR003607 HD/PDEase domain TO73_0720 5bb9a45d635bbcd363a04b4c36b66c33 438 Pfam PF01966 HD domain 230 348 1.2E-14 T 11-10-2018 IPR006674 HD domain TO73_0720 5bb9a45d635bbcd363a04b4c36b66c33 438 SUPERFAMILY SSF81301 16 121 1.63E-14 T 11-10-2018 TO73_0720 5bb9a45d635bbcd363a04b4c36b66c33 438 Gene3D G3DSA:3.30.460.10 13 106 1.5E-11 T 11-10-2018 TO73_0720 5bb9a45d635bbcd363a04b4c36b66c33 438 Gene3D G3DSA:1.10.3090.10 125 416 3.9E-32 T 11-10-2018 TO73_0720 5bb9a45d635bbcd363a04b4c36b66c33 438 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 152 214 4.5E-9 T 11-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TO73_0013 7e5f4416adfa7a437833bf9ce14140ca 303 Gene3D G3DSA:3.40.50.1100 7 297 1.3E-121 T 11-10-2018 TO73_0013 7e5f4416adfa7a437833bf9ce14140ca 303 Gene3D G3DSA:3.40.50.1100 34 155 1.3E-121 T 11-10-2018 TO73_0013 7e5f4416adfa7a437833bf9ce14140ca 303 SUPERFAMILY SSF53686 3 301 7.6E-98 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TO73_0013 7e5f4416adfa7a437833bf9ce14140ca 303 TIGRFAM TIGR01139 cysK: cysteine synthase A 4 301 1.0E-124 T 11-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 TO73_0013 7e5f4416adfa7a437833bf9ce14140ca 303 TIGRFAM TIGR01136 cysKM: cysteine synthase 4 301 2.4E-124 T 11-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 TO73_0013 7e5f4416adfa7a437833bf9ce14140ca 303 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 4 289 5.8E-69 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TO73_0013 7e5f4416adfa7a437833bf9ce14140ca 303 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 29 47 - T 11-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 TO73_2002 ff2e157af109937072b0367c382087a8 377 SUPERFAMILY SSF48256 4 376 8.64E-131 T 11-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 TO73_2002 ff2e157af109937072b0367c382087a8 377 PRINTS PR00143 Citrate synthase signature 328 342 7.8E-42 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 TO73_2002 ff2e157af109937072b0367c382087a8 377 PRINTS PR00143 Citrate synthase signature 248 268 7.8E-42 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 TO73_2002 ff2e157af109937072b0367c382087a8 377 PRINTS PR00143 Citrate synthase signature 195 223 7.8E-42 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 TO73_2002 ff2e157af109937072b0367c382087a8 377 PRINTS PR00143 Citrate synthase signature 173 188 7.8E-42 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 TO73_2002 ff2e157af109937072b0367c382087a8 377 PRINTS PR00143 Citrate synthase signature 308 324 7.8E-42 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 TO73_2002 ff2e157af109937072b0367c382087a8 377 PRINTS PR00143 Citrate synthase signature 124 137 7.8E-42 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 TO73_2002 ff2e157af109937072b0367c382087a8 377 Gene3D G3DSA:1.10.580.10 20 347 2.2E-142 T 11-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TO73_2002 ff2e157af109937072b0367c382087a8 377 Pfam PF00285 Citrate synthase, C-terminal domain 6 358 6.6E-127 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 TO73_2002 ff2e157af109937072b0367c382087a8 377 Gene3D G3DSA:1.10.230.10 221 322 2.2E-142 T 11-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain TO73_2002 ff2e157af109937072b0367c382087a8 377 PIRSF PIRSF001369 1 377 3.4E-156 T 11-10-2018 IPR024176 Citrate synthase, bacterial-type TO73_2002 ff2e157af109937072b0367c382087a8 377 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 376 2.0E-147 T 11-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 TO73_0756 549f1df551c4575ca20f4215258e0675 661 Gene3D G3DSA:1.10.1060.10 249 379 1.8E-17 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TO73_0756 549f1df551c4575ca20f4215258e0675 661 SUPERFAMILY SSF46548 266 373 8.37E-21 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TO73_0756 549f1df551c4575ca20f4215258e0675 661 Pfam PF02754 Cysteine-rich domain 425 510 5.9E-17 T 11-10-2018 IPR004017 Cysteine-rich domain TO73_0756 549f1df551c4575ca20f4215258e0675 661 Pfam PF02754 Cysteine-rich domain 548 635 5.6E-16 T 11-10-2018 IPR004017 Cysteine-rich domain TO73_0756 549f1df551c4575ca20f4215258e0675 661 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 346 357 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_0756 549f1df551c4575ca20f4215258e0675 661 Pfam PF13183 4Fe-4S dicluster domain 281 360 2.4E-12 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_1445 647898f7be51e838b8501026c2648377 126 Pfam PF08332 Calcium/calmodulin dependent protein kinase II association domain 3 125 1.3E-46 T 11-10-2018 IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain GO:0004683|GO:0005516|GO:0006468 Reactome: R-HSA-3371571|Reactome: R-HSA-399719|Reactome: R-HSA-438066|Reactome: R-HSA-442729|Reactome: R-HSA-442742|Reactome: R-HSA-442982|Reactome: R-HSA-5576892|Reactome: R-HSA-5578775|Reactome: R-HSA-5673001|Reactome: R-HSA-877300|Reactome: R-HSA-936837 TO73_1445 647898f7be51e838b8501026c2648377 126 Gene3D G3DSA:3.10.450.50 1 126 5.3E-27 T 11-10-2018 TO73_1445 647898f7be51e838b8501026c2648377 126 SUPERFAMILY SSF54427 2 124 2.9E-22 T 11-10-2018 IPR032710 NTF2-like domain superfamily TO73_2350 af45b34e4d4403267a8c2b36da707e23 179 SUPERFAMILY SSF52980 5 134 5.36E-26 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_2350 af45b34e4d4403267a8c2b36da707e23 179 Pfam PF05685 Putative restriction endonuclease 12 162 3.2E-28 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_2350 af45b34e4d4403267a8c2b36da707e23 179 Gene3D G3DSA:3.90.1570.10 3 153 4.9E-19 T 11-10-2018 TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 SUPERFAMILY SSF52335 3 184 5.89E-59 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 496 8.7E-185 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 Pfam PF02142 MGS-like domain 12 122 1.8E-21 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 PIRSF PIRSF000414 2 496 1.6E-195 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 496 41.506 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 Gene3D G3DSA:3.40.140.20 371 496 2.3E-53 T 11-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 SMART SM00851 12 123 4.6E-44 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 SMART SM00798 128 431 6.9E-180 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 Gene3D G3DSA:3.40.140.20 192 346 6.4E-60 T 11-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 SUPERFAMILY SSF53927 197 496 2.41E-120 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 Pfam PF01808 AICARFT/IMPCHase bienzyme 128 429 2.0E-112 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0844 6991b8315e33f7409a6d7738f9c6c4ee 496 Gene3D G3DSA:3.40.50.1380 1 189 1.8E-75 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TO73_0167 7a0ae9f3933efbf53e922fe603bef19b 75 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 5 72 1.6E-16 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TO73_0167 7a0ae9f3933efbf53e922fe603bef19b 75 PRINTS PR01651 Protein-export SecG membrane protein signature 54 75 7.8E-7 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TO73_0167 7a0ae9f3933efbf53e922fe603bef19b 75 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 7.8E-7 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TO73_0167 7a0ae9f3933efbf53e922fe603bef19b 75 Pfam PF03840 Preprotein translocase SecG subunit 8 72 2.3E-14 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 60 8.5E-20 T 11-10-2018 IPR013185 Translation elongation factor, KOW-like TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 SMART SM01185 67 120 4.0E-23 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 SMART SM00841 128 183 1.8E-34 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 Gene3D G3DSA:2.40.50.140 64 126 1.0E-26 T 11-10-2018 TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 Pfam PF09285 Elongation factor P, C-terminal 128 183 2.0E-27 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 SUPERFAMILY SSF50249 128 184 2.74E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 TIGRFAM TIGR00038 efp: translation elongation factor P 2 184 4.1E-71 T 11-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 SUPERFAMILY SSF50249 65 126 6.43E-17 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 PIRSF PIRSF005901 1 184 3.4E-70 T 11-10-2018 IPR020599 Translation elongation factor P/YeiP TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 11-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 Hamap MF_00141 Elongation factor P [efp]. 1 184 46.27 T 11-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 Gene3D G3DSA:2.30.30.30 1 63 5.2E-28 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 SUPERFAMILY SSF50104 1 62 6.62E-17 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 Gene3D G3DSA:2.40.50.140 127 184 3.3E-29 T 11-10-2018 TO73_0748 a85b766f10bf928e0942df76ad39b14b 184 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 1.0E-19 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TO73_1980 68ee66cd73893c64e792284e7bfde050 144 Pfam PF00293 NUDIX domain 9 135 2.4E-18 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TO73_1980 68ee66cd73893c64e792284e7bfde050 144 PRINTS PR00502 NUDIX hydrolase family signature 34 48 8.8E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_1980 68ee66cd73893c64e792284e7bfde050 144 PRINTS PR00502 NUDIX hydrolase family signature 48 63 8.8E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_1980 68ee66cd73893c64e792284e7bfde050 144 SUPERFAMILY SSF55811 5 142 4.87E-27 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TO73_1980 68ee66cd73893c64e792284e7bfde050 144 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TO73_1980 68ee66cd73893c64e792284e7bfde050 144 Gene3D G3DSA:3.90.79.10 6 142 2.6E-31 T 11-10-2018 TO73_1419 36015a0bdb926920641929819c03997a 180 SUPERFAMILY SSF52980 5 175 1.72E-28 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1419 36015a0bdb926920641929819c03997a 180 Pfam PF05685 Putative restriction endonuclease 12 166 4.3E-33 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1419 36015a0bdb926920641929819c03997a 180 Gene3D G3DSA:3.90.1570.10 3 176 5.8E-20 T 11-10-2018 TO73_1610 08003496c9db24d1f456e46091cf5192 121 Pfam PF12723 Protein of unknown function (DUF3809) 18 113 2.6E-15 T 11-10-2018 IPR024219 Protein of unknown function DUF3809 TO73_1610 08003496c9db24d1f456e46091cf5192 121 Gene3D G3DSA:3.30.530.70 12 120 2.8E-12 T 11-10-2018 TO73_0389 7c9563c6dfde42ffa042b13f3662702c 61 SUPERFAMILY SSF57716 6 61 1.85E-21 T 11-10-2018 TO73_0389 7c9563c6dfde42ffa042b13f3662702c 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 11-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0389 7c9563c6dfde42ffa042b13f3662702c 61 Pfam PF00253 Ribosomal protein S14p/S29e 10 60 8.2E-24 T 11-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0389 7c9563c6dfde42ffa042b13f3662702c 61 Gene3D G3DSA:4.10.830.10 1 61 4.7E-32 T 11-10-2018 TO73_0389 7c9563c6dfde42ffa042b13f3662702c 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.669 T 11-10-2018 IPR023053 Ribosomal protein S14, type Z TO73_2348 bcf4fcab8822a9080458733f3e87bfbd 223 Gene3D G3DSA:3.10.20.30 3 77 1.0E-20 T 11-10-2018 IPR012675 Beta-grasp domain superfamily TO73_2348 bcf4fcab8822a9080458733f3e87bfbd 223 Pfam PF02597 ThiS family 5 79 4.0E-16 T 11-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TO73_2348 bcf4fcab8822a9080458733f3e87bfbd 223 SUPERFAMILY SSF54690 83 215 7.32E-49 T 11-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TO73_2348 bcf4fcab8822a9080458733f3e87bfbd 223 Pfam PF02391 MoaE protein 85 196 3.1E-41 T 11-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TO73_2348 bcf4fcab8822a9080458733f3e87bfbd 223 SUPERFAMILY SSF54285 1 77 1.87E-17 T 11-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TO73_2348 bcf4fcab8822a9080458733f3e87bfbd 223 Gene3D G3DSA:3.90.1170.40 78 215 7.8E-53 T 11-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 4 125 1.5E-66 T 11-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 Pfam PF00164 Ribosomal protein S12/S23 14 125 9.9E-43 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 ProSitePatterns PS00055 Ribosomal protein S12 signature. 45 52 - T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 SUPERFAMILY SSF50249 4 126 1.88E-52 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 3 125 39.687 T 11-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 PRINTS PR01034 Ribosomal protein S12 signature 44 59 2.1E-57 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 PRINTS PR01034 Ribosomal protein S12 signature 96 112 2.1E-57 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 PRINTS PR01034 Ribosomal protein S12 signature 29 44 2.1E-57 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 PRINTS PR01034 Ribosomal protein S12 signature 112 124 2.1E-57 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 PRINTS PR01034 Ribosomal protein S12 signature 60 79 2.1E-57 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 PRINTS PR01034 Ribosomal protein S12 signature 79 96 2.1E-57 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 Gene3D G3DSA:2.40.50.140 1 134 7.3E-66 T 11-10-2018 TO73_0371 7dabd4ef1deea61263a9d29712267c86 136 PIRSF PIRSF002133 3 126 3.1E-55 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 Gene3D G3DSA:2.30.22.10 116 177 1.5E-24 T 11-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 Hamap MF_01151 Protein GrpE [grpE]. 2 169 18.173 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 Pfam PF01025 GrpE 12 168 1.1E-42 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 PRINTS PR00773 GrpE protein signature 44 60 1.6E-26 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 PRINTS PR00773 GrpE protein signature 72 87 1.6E-26 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 PRINTS PR00773 GrpE protein signature 148 167 1.6E-26 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 PRINTS PR00773 GrpE protein signature 124 139 1.6E-26 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 Gene3D G3DSA:3.90.20.20 2 115 1.9E-36 T 11-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 SUPERFAMILY SSF58014 22 116 9.29E-23 T 11-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 ProSitePatterns PS01071 grpE protein signature. 127 167 - T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TO73_1922 527461a7622f404ac3884eb35efdfc04 179 SUPERFAMILY SSF51064 117 170 5.23E-12 T 11-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TO73_1173 eb2b7d0729478e6fded6a59a31386229 252 Pfam PF09684 Phage tail protein (Tail_P2_I) 29 175 7.5E-8 T 11-10-2018 IPR006521 Tail protein I TO73_0260 04e78681ce36d890bfca662218231559 396 PIRSF PIRSF000521 171 396 1.4E-37 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0260 04e78681ce36d890bfca662218231559 396 PIRSF PIRSF000521 130 158 9.8 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0260 04e78681ce36d890bfca662218231559 396 PIRSF PIRSF000521 14 141 8.8E-8 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0260 04e78681ce36d890bfca662218231559 396 Pfam PF00202 Aminotransferase class-III 29 393 2.7E-116 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0260 04e78681ce36d890bfca662218231559 396 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 23 394 2.2E-138 T 11-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TO73_0260 04e78681ce36d890bfca662218231559 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 222 259 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0260 04e78681ce36d890bfca662218231559 396 SUPERFAMILY SSF53383 23 395 4.57E-131 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_0260 04e78681ce36d890bfca662218231559 396 Gene3D G3DSA:3.90.1150.10 30 388 2.0E-161 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_0260 04e78681ce36d890bfca662218231559 396 Gene3D G3DSA:3.40.640.10 63 304 2.0E-161 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_0260 04e78681ce36d890bfca662218231559 396 Hamap MF_02084 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase [lysJ]. 21 395 50.1 T 11-10-2018 IPR037537 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase GO:0008483 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 Gene3D G3DSA:1.10.10.350 371 468 1.1E-33 T 11-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 SUPERFAMILY SSF48163 306 467 1.57E-50 T 11-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 SUPERFAMILY SSF52374 1 300 3.84E-111 T 11-10-2018 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 Gene3D G3DSA:1.10.1160.10 238 322 1.9E-33 T 11-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 Gene3D G3DSA:3.90.800.10 71 186 2.2E-102 T 11-10-2018 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 Gene3D G3DSA:3.40.50.620 4 235 2.2E-102 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 Gene3D G3DSA:1.10.8.70 323 370 1.9E-22 T 11-10-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 465 5.9E-140 T 11-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 5 17 2.4E-21 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 30 2.4E-21 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 185 195 2.4E-21 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 201 209 2.4E-21 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 34 47 2.4E-21 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 312 9.0E-110 T 11-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 8 19 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_0648 0085c59456ddcb76c7a47e1aa0555421 468 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 1 467 31.476 T 11-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TO73_1790 4d1730199d78c3e3c97ae1a9e0c06f22 307 Gene3D G3DSA:3.30.2350.10 63 281 6.1E-71 T 11-10-2018 TO73_1790 4d1730199d78c3e3c97ae1a9e0c06f22 307 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 128 142 - T 11-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_1790 4d1730199d78c3e3c97ae1a9e0c06f22 307 Pfam PF00849 RNA pseudouridylate synthase 80 235 8.7E-32 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_1790 4d1730199d78c3e3c97ae1a9e0c06f22 307 Gene3D G3DSA:3.10.290.10 1 62 1.5E-14 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TO73_1790 4d1730199d78c3e3c97ae1a9e0c06f22 307 SMART SM00363 9 71 3.7E-12 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_1790 4d1730199d78c3e3c97ae1a9e0c06f22 307 Pfam PF01479 S4 domain 10 55 2.0E-11 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_1790 4d1730199d78c3e3c97ae1a9e0c06f22 307 SUPERFAMILY SSF55174 8 57 2.55E-10 T 11-10-2018 TO73_1790 4d1730199d78c3e3c97ae1a9e0c06f22 307 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 7 291 3.7E-81 T 11-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_1790 4d1730199d78c3e3c97ae1a9e0c06f22 307 SUPERFAMILY SSF55120 66 292 1.65E-71 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_1774 c9675de20f17cafc3d4d63d3c3a2fe74 162 ProSitePatterns PS00893 Nudix box signature. 59 80 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TO73_1774 c9675de20f17cafc3d4d63d3c3a2fe74 162 SUPERFAMILY SSF55811 16 157 9.21E-40 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TO73_1774 c9675de20f17cafc3d4d63d3c3a2fe74 162 PRINTS PR00502 NUDIX hydrolase family signature 54 68 2.9E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_1774 c9675de20f17cafc3d4d63d3c3a2fe74 162 PRINTS PR00502 NUDIX hydrolase family signature 68 83 2.9E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_1774 c9675de20f17cafc3d4d63d3c3a2fe74 162 Pfam PF00293 NUDIX domain 25 138 7.6E-22 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TO73_1774 c9675de20f17cafc3d4d63d3c3a2fe74 162 Gene3D G3DSA:3.90.79.10 1 162 9.0E-57 T 11-10-2018 TO73_1393 7f3b1eb1cbdfe765e281cb6fb5558666 881 SUPERFAMILY SSF46894 691 748 5.78E-6 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TO73_1393 7f3b1eb1cbdfe765e281cb6fb5558666 881 Gene3D G3DSA:1.25.40.10 346 634 5.3E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1393 7f3b1eb1cbdfe765e281cb6fb5558666 881 SUPERFAMILY SSF52540 23 147 3.53E-5 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1393 7f3b1eb1cbdfe765e281cb6fb5558666 881 Gene3D G3DSA:1.10.10.10 669 763 4.4E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1393 7f3b1eb1cbdfe765e281cb6fb5558666 881 SUPERFAMILY SSF48452 405 521 2.66E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1393 7f3b1eb1cbdfe765e281cb6fb5558666 881 SMART SM01043 761 880 0.0072 T 11-10-2018 IPR005158 Bacterial transcriptional activator domain TO73_1393 7f3b1eb1cbdfe765e281cb6fb5558666 881 SUPERFAMILY SSF48452 771 879 1.28E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0907 0e4717cfe1edd47da1e623efdfc81059 214 SMART SM00855 4 152 4.9E-17 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TO73_0907 0e4717cfe1edd47da1e623efdfc81059 214 SUPERFAMILY SSF53254 1 192 3.14E-41 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_0907 0e4717cfe1edd47da1e623efdfc81059 214 Gene3D G3DSA:3.40.50.1240 1 191 5.9E-36 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_0907 0e4717cfe1edd47da1e623efdfc81059 214 PIRSF PIRSF000709 1 165 3.5E-6 T 11-10-2018 TO73_0907 0e4717cfe1edd47da1e623efdfc81059 214 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 190 6.5E-41 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TO73_2331 07e1eedb4467202f9c177a4fb8e8898a 407 Gene3D G3DSA:3.20.20.20 1 288 2.6E-105 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_2331 07e1eedb4467202f9c177a4fb8e8898a 407 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 5 395 7.1E-116 T 11-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TO73_2331 07e1eedb4467202f9c177a4fb8e8898a 407 SUPERFAMILY SSF56014 293 401 1.83E-6 T 11-10-2018 TO73_2331 07e1eedb4467202f9c177a4fb8e8898a 407 Pfam PF04551 GcpE protein 9 395 3.3E-112 T 11-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TO73_2331 07e1eedb4467202f9c177a4fb8e8898a 407 Gene3D G3DSA:3.30.413.10 289 406 1.3E-40 T 11-10-2018 TO73_2331 07e1eedb4467202f9c177a4fb8e8898a 407 PIRSF PIRSF004640 1 405 3.7E-129 T 11-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TO73_2331 07e1eedb4467202f9c177a4fb8e8898a 407 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 3 399 30.906 T 11-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 Gene3D G3DSA:2.130.10.30 459 533 1.1E-11 T 11-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 181 229 3.8E-15 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 232 277 1.0E-8 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 333 391 4.1E-9 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 280 313 4.2E-7 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 500 531 2.5E-9 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 SUPERFAMILY SSF50985 167 452 1.96E-67 T 11-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 Gene3D G3DSA:2.130.10.30 148 358 2.4E-52 T 11-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 281 297 8.4E-18 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 183 199 8.4E-18 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 216 229 8.4E-18 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 235 251 8.4E-18 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 496 517 8.4E-18 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 336 350 8.4E-18 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 219 229 - T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1099 e98ab97fabe8f117e0ec7c1d6e039045 534 Gene3D G3DSA:2.130.10.30 359 458 1.1E-17 T 11-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II TO73_1845 78350a1e32c3fc30fd755d2cfb810c99 351 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 11-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TO73_1845 78350a1e32c3fc30fd755d2cfb810c99 351 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 318 3.5E-75 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TO73_1845 78350a1e32c3fc30fd755d2cfb810c99 351 Gene3D G3DSA:3.40.50.1100 60 156 4.3E-133 T 11-10-2018 TO73_1845 78350a1e32c3fc30fd755d2cfb810c99 351 Gene3D G3DSA:3.40.50.1100 8 324 4.3E-133 T 11-10-2018 TO73_1845 78350a1e32c3fc30fd755d2cfb810c99 351 TIGRFAM TIGR00260 thrC: threonine synthase 6 324 1.4E-92 T 11-10-2018 IPR004450 Threonine synthase-like TO73_1845 78350a1e32c3fc30fd755d2cfb810c99 351 PIRSF PIRSF038945 2 350 6.9E-160 T 11-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TO73_1845 78350a1e32c3fc30fd755d2cfb810c99 351 SUPERFAMILY SSF53686 6 344 1.02E-101 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 419 579 1.1E-7 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 1.1E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 565 575 1.1E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 1.1E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 532 554 1.1E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 493 511 1.1E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 1.1E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 1.1E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 SUPERFAMILY SSF50677 226 417 8.9E-57 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 876 0.0 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Pfam PF09334 tRNA synthetases class I (M) 36 176 5.8E-19 T 11-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Gene3D G3DSA:3.10.20.590 815 878 1.2E-25 T 11-10-2018 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 SUPERFAMILY SSF47323 681 876 1.05E-36 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 SUPERFAMILY SSF52374 3 686 2.35E-155 T 11-10-2018 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Gene3D G3DSA:3.40.50.620 34 646 0.0 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Gene3D G3DSA:1.10.730.10 655 813 2.2E-57 T 11-10-2018 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Pfam PF14795 Leucine-tRNA synthetase-specific domain 580 635 2.6E-29 T 11-10-2018 IPR023356 Leucyl-tRNA synthetase, domain 3 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 876 22.945 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Gene3D G3DSA:3.90.740.10 228 417 0.0 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 406 1.2E-69 T 11-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Pfam PF08264 Anticodon-binding domain of tRNA 718 842 1.7E-23 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 Gene3D G3DSA:2.30.210.10 580 636 0.0 T 11-10-2018 TO73_2354 eb34088b3687639933dbfeaa0d202495 878 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 Gene3D G3DSA:1.20.200.10 114 369 7.2E-91 T 11-10-2018 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 ProSitePatterns PS00163 Fumarate lyases signature. 282 291 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 PRINTS PR00149 Fumarate lyase superfamily signature 154 172 4.9E-22 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 PRINTS PR00149 Fumarate lyase superfamily signature 109 127 4.9E-22 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 4.9E-22 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 PRINTS PR00149 Fumarate lyase superfamily signature 282 298 4.9E-22 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 Pfam PF10397 Adenylosuccinate lyase C-terminus 371 447 1.1E-21 T 11-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 6.4E-6 T 11-10-2018 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 PRINTS PR00145 Argininosuccinate lyase family signature 108 130 6.4E-6 T 11-10-2018 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 PRINTS PR00145 Argininosuccinate lyase family signature 282 298 6.4E-6 T 11-10-2018 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 SUPERFAMILY SSF48557 17 446 4.08E-117 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 Gene3D G3DSA:1.10.275.10 9 113 3.0E-23 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 Pfam PF00206 Lyase 19 302 2.0E-48 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 Gene3D G3DSA:1.10.40.30 370 449 2.8E-25 T 11-10-2018 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 14 447 4.3E-136 T 11-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0447 753cf411e14ae4d046dbe0252f2c3172 449 SMART SM00998 370 448 5.5E-32 T 11-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 Pfam PF01872 RibD C-terminal domain 154 375 2.3E-41 T 11-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 153 380 1.1E-50 T 11-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 SUPERFAMILY SSF53597 152 380 2.62E-52 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 Gene3D G3DSA:3.40.430.10 143 381 2.3E-64 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 16 376 1.5E-104 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 Gene3D G3DSA:3.40.140.10 6 142 9.5E-42 T 11-10-2018 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 96 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 PIRSF PIRSF006769 6 383 2.8E-128 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 SUPERFAMILY SSF53927 11 152 5.35E-46 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TO73_0693 3d160a142f2c9376ec2606cb444eb268 383 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 107 2.0E-19 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 SMART SM00490 454 540 3.9E-17 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 Hamap MF_00204 UvrABC system protein B [uvrB]. 1 646 42.674 T 11-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 Gene3D G3DSA:3.40.50.300 409 583 9.7E-49 T 11-10-2018 TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 9 643 1.0E-304 T 11-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 Pfam PF12344 Ultra-violet resistance protein B 546 587 6.5E-21 T 11-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 Pfam PF02151 UvrB/uvrC motif 612 645 4.9E-8 T 11-10-2018 IPR001943 UVR domain GO:0005515 TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 Pfam PF04851 Type III restriction enzyme, res subunit 13 135 6.1E-11 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 SMART SM00487 6 419 6.1E-27 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 SUPERFAMILY SSF52540 7 409 6.83E-126 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 SUPERFAMILY SSF52540 32 567 4.13E-34 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 Gene3D G3DSA:4.10.860.10 598 648 7.7E-6 T 11-10-2018 TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 Gene3D G3DSA:3.40.50.300 1 230 2.0E-69 T 11-10-2018 TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 Gene3D G3DSA:3.40.50.300 262 408 3.9E-54 T 11-10-2018 TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 SUPERFAMILY SSF46600 608 648 2.48E-9 T 11-10-2018 IPR036876 UVR domain superfamily TO73_2302 1bd6635e864ce4f6fada96e2c8cc4e95 665 Pfam PF00271 Helicase conserved C-terminal domain 433 539 7.7E-17 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_1447 852e7f98be96555f219748b34bf18cc5 844 Gene3D G3DSA:3.30.450.40 77 237 1.1E-27 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1447 852e7f98be96555f219748b34bf18cc5 844 Pfam PF13193 AMP-binding enzyme C-terminal domain 734 813 4.2E-19 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TO73_1447 852e7f98be96555f219748b34bf18cc5 844 Gene3D G3DSA:1.10.10.10 5 69 1.4E-11 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1447 852e7f98be96555f219748b34bf18cc5 844 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 268 317 9.2E-14 T 11-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TO73_1447 852e7f98be96555f219748b34bf18cc5 844 Gene3D G3DSA:3.40.50.12780 309 721 8.8E-94 T 11-10-2018 TO73_1447 852e7f98be96555f219748b34bf18cc5 844 SUPERFAMILY SSF56801 266 825 2.22E-137 T 11-10-2018 TO73_1447 852e7f98be96555f219748b34bf18cc5 844 ProSitePatterns PS00455 Putative AMP-binding domain signature. 481 492 - T 11-10-2018 IPR020845 AMP-binding, conserved site TO73_1447 852e7f98be96555f219748b34bf18cc5 844 Pfam PF09339 IclR helix-turn-helix domain 13 56 4.1E-10 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TO73_1447 852e7f98be96555f219748b34bf18cc5 844 Pfam PF00501 AMP-binding enzyme 325 725 9.4E-76 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_1447 852e7f98be96555f219748b34bf18cc5 844 SUPERFAMILY SSF55781 79 225 5.89E-21 T 11-10-2018 TO73_1447 852e7f98be96555f219748b34bf18cc5 844 Pfam PF01614 Bacterial transcriptional regulator 124 210 2.5E-15 T 11-10-2018 IPR014757 Transcription regulator IclR, C-terminal TO73_1447 852e7f98be96555f219748b34bf18cc5 844 SUPERFAMILY SSF46785 8 65 2.0E-9 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1447 852e7f98be96555f219748b34bf18cc5 844 Gene3D G3DSA:3.30.300.30 722 824 1.8E-20 T 11-10-2018 TO73_0440 812a55034dc889eacbd55d61402d5967 725 Gene3D G3DSA:3.90.650.10 553 725 3.2E-46 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TO73_0440 812a55034dc889eacbd55d61402d5967 725 SUPERFAMILY SSF56042 191 414 1.5E-48 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TO73_0440 812a55034dc889eacbd55d61402d5967 725 SUPERFAMILY SSF56042 556 723 2.09E-36 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TO73_0440 812a55034dc889eacbd55d61402d5967 725 Gene3D G3DSA:3.30.1330.10 370 552 3.9E-58 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TO73_0440 812a55034dc889eacbd55d61402d5967 725 Gene3D G3DSA:3.90.650.10 14 362 1.4E-143 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TO73_0440 812a55034dc889eacbd55d61402d5967 725 Pfam PF00586 AIR synthase related protein, N-terminal domain 430 546 4.7E-18 T 11-10-2018 IPR016188 PurM-like, N-terminal domain TO73_0440 812a55034dc889eacbd55d61402d5967 725 Pfam PF00586 AIR synthase related protein, N-terminal domain 79 180 1.1E-24 T 11-10-2018 IPR016188 PurM-like, N-terminal domain TO73_0440 812a55034dc889eacbd55d61402d5967 725 Gene3D G3DSA:3.30.1330.10 36 185 1.4E-143 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TO73_0440 812a55034dc889eacbd55d61402d5967 725 Pfam PF02769 AIR synthase related protein, C-terminal domain 204 344 3.4E-29 T 11-10-2018 IPR010918 PurM-like, C-terminal domain TO73_0440 812a55034dc889eacbd55d61402d5967 725 Pfam PF02769 AIR synthase related protein, C-terminal domain 559 694 1.3E-16 T 11-10-2018 IPR010918 PurM-like, C-terminal domain TO73_0440 812a55034dc889eacbd55d61402d5967 725 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 12 722 8.3E-263 T 11-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_0440 812a55034dc889eacbd55d61402d5967 725 PIRSF PIRSF001587 1 725 1.6E-291 T 11-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_0440 812a55034dc889eacbd55d61402d5967 725 SUPERFAMILY SSF55326 7 184 2.24E-51 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TO73_0440 812a55034dc889eacbd55d61402d5967 725 SUPERFAMILY SSF55326 384 548 1.06E-43 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TO73_0440 812a55034dc889eacbd55d61402d5967 725 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 725 276.715 T 11-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_1117 4a2145c2f2b3dc39fba169d80e16c88c 239 Gene3D G3DSA:3.40.1280.10 1 170 4.0E-63 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TO73_1117 4a2145c2f2b3dc39fba169d80e16c88c 239 Gene3D G3DSA:1.10.1270.20 171 239 2.6E-25 T 11-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TO73_1117 4a2145c2f2b3dc39fba169d80e16c88c 239 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 239 96.415 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TO73_1117 4a2145c2f2b3dc39fba169d80e16c88c 239 PIRSF PIRSF000386 1 238 1.5E-96 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TO73_1117 4a2145c2f2b3dc39fba169d80e16c88c 239 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 220 5.1E-83 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TO73_1117 4a2145c2f2b3dc39fba169d80e16c88c 239 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 24 216 2.6E-61 T 11-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TO73_1117 4a2145c2f2b3dc39fba169d80e16c88c 239 SUPERFAMILY SSF75217 1 236 1.64E-86 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases TO73_1020 9b5f63263c2857df6041e0957c873209 307 Gene3D G3DSA:3.40.50.10800 172 262 1.6E-108 T 11-10-2018 TO73_1020 9b5f63263c2857df6041e0957c873209 307 Gene3D G3DSA:3.40.50.10800 88 304 1.6E-108 T 11-10-2018 TO73_1020 9b5f63263c2857df6041e0957c873209 307 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 306 41.991 T 11-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TO73_1020 9b5f63263c2857df6041e0957c873209 307 Gene3D G3DSA:3.40.50.10800 9 287 1.6E-108 T 11-10-2018 TO73_1020 9b5f63263c2857df6041e0957c873209 307 SUPERFAMILY SSF142754 6 305 5.1E-104 T 11-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TO73_1020 9b5f63263c2857df6041e0957c873209 307 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 3 306 1.1E-92 T 11-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TO73_1020 9b5f63263c2857df6041e0957c873209 307 Pfam PF02445 Quinolinate synthetase A protein 9 304 5.0E-107 T 11-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 PRINTS PR00992 Alanine racemase signature 124 136 5.8E-41 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 PRINTS PR00992 Alanine racemase signature 332 345 5.8E-41 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 PRINTS PR00992 Alanine racemase signature 63 81 5.8E-41 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 PRINTS PR00992 Alanine racemase signature 242 257 5.8E-41 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 PRINTS PR00992 Alanine racemase signature 259 274 5.8E-41 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 PRINTS PR00992 Alanine racemase signature 27 43 5.8E-41 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 PRINTS PR00992 Alanine racemase signature 157 168 5.8E-41 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 PRINTS PR00992 Alanine racemase signature 279 296 5.8E-41 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 SUPERFAMILY SSF51419 10 227 1.57E-53 T 11-10-2018 IPR029066 PLP-binding barrel TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 SMART SM01005 226 350 4.7E-41 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 Gene3D G3DSA:3.20.20.10 13 220 2.1E-54 T 11-10-2018 IPR029066 PLP-binding barrel TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 Pfam PF01168 Alanine racemase, N-terminal domain 10 219 1.9E-54 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 TIGRFAM TIGR00492 alr: alanine racemase 6 350 1.9E-67 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 SUPERFAMILY SSF50621 215 350 7.32E-35 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 Hamap MF_01201 Alanine racemase. 3 350 27.225 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 Gene3D G3DSA:2.40.37.10 221 357 5.4E-32 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TO73_2374 5a14a3f56fba621e43bff51738e571e2 361 Pfam PF00842 Alanine racemase, C-terminal domain 226 349 4.0E-29 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 Gene3D G3DSA:1.20.120.140 4 303 2.7E-124 T 11-10-2018 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 Pfam PF02978 Signal peptide binding domain 320 413 2.8E-30 T 11-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 SMART SM00963 1 86 2.4E-27 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 428 32.913 T 11-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 Pfam PF00448 SRP54-type protein, GTPase domain 100 293 4.9E-68 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 414 2.8E-160 T 11-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 SUPERFAMILY SSF47446 295 416 1.24E-36 T 11-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 Gene3D G3DSA:3.40.50.300 90 282 2.7E-124 T 11-10-2018 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 Gene3D G3DSA:1.10.260.30 319 425 3.5E-41 T 11-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 SMART SM00962 98 293 1.4E-104 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 SUPERFAMILY SSF52540 94 295 7.14E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 266 279 - T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 SMART SM00382 97 244 2.8E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 6.9E-19 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_1121 9d1d2e74922c7fd4c1b26146ab8efa41 430 SUPERFAMILY SSF47364 1 89 2.49E-23 T 11-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TO73_0654 18f645b57903bea2759b85f0ec834965 79 Pfam PF00825 Ribonuclease P 10 74 1.4E-18 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TO73_0654 18f645b57903bea2759b85f0ec834965 79 Gene3D G3DSA:3.30.230.10 2 79 1.0E-19 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0654 18f645b57903bea2759b85f0ec834965 79 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 1 64 3.0E-17 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TO73_0654 18f645b57903bea2759b85f0ec834965 79 SUPERFAMILY SSF54211 8 77 8.6E-19 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0654 18f645b57903bea2759b85f0ec834965 79 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 10 74 5.3E-12 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TO73_0654 18f645b57903bea2759b85f0ec834965 79 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 21 35 - T 11-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 TO73_0008 707721f982793994899d0d3e5ba43bb7 615 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 608 42.02 T 11-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TO73_0008 707721f982793994899d0d3e5ba43bb7 615 Gene3D G3DSA:3.40.50.920 484 613 5.7E-42 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_0008 707721f982793994899d0d3e5ba43bb7 615 SUPERFAMILY SSF52518 307 493 2.72E-53 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_0008 707721f982793994899d0d3e5ba43bb7 615 SMART SM00861 309 473 7.6E-63 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_0008 707721f982793994899d0d3e5ba43bb7 615 SUPERFAMILY SSF52518 3 371 7.49E-71 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_0008 707721f982793994899d0d3e5ba43bb7 615 Pfam PF02780 Transketolase, C-terminal domain 484 599 4.5E-25 T 11-10-2018 IPR033248 Transketolase, C-terminal domain TO73_0008 707721f982793994899d0d3e5ba43bb7 615 Gene3D G3DSA:3.40.50.970 306 483 9.0E-69 T 11-10-2018 TO73_0008 707721f982793994899d0d3e5ba43bb7 615 ProSitePatterns PS00802 Transketolase signature 2. 415 431 - T 11-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TO73_0008 707721f982793994899d0d3e5ba43bb7 615 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 275 8.0E-114 T 11-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TO73_0008 707721f982793994899d0d3e5ba43bb7 615 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 603 3.4E-220 T 11-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TO73_0008 707721f982793994899d0d3e5ba43bb7 615 Pfam PF02779 Transketolase, pyrimidine binding domain 309 471 1.3E-40 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_0008 707721f982793994899d0d3e5ba43bb7 615 SUPERFAMILY SSF52922 481 605 6.02E-27 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 Gene3D G3DSA:3.40.50.10990 206 378 1.4E-78 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 SUPERFAMILY SSF55821 6 201 1.26E-84 T 11-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TO73_0695 3e698950744c3fa461f841f4f33d2888 399 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 205 399 43.069 T 11-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 9 198 1.2E-86 T 11-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 SUPERFAMILY SSF142695 206 375 8.37E-77 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 203 39.6 T 11-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 7 199 3.1E-72 T 11-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 209 397 1.7E-82 T 11-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 Gene3D G3DSA:3.90.870.10 2 203 9.7E-90 T 11-10-2018 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 PIRSF PIRSF001259 3 399 7.1E-178 T 11-10-2018 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 3 396 54.156 T 11-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TO73_0695 3e698950744c3fa461f841f4f33d2888 399 Pfam PF00925 GTP cyclohydrolase II 209 374 2.7E-77 T 11-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TO73_0463 e5b9cb8d690728ef56564cb3f2227eeb 230 Gene3D G3DSA:1.10.10.10 130 230 2.8E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0463 e5b9cb8d690728ef56564cb3f2227eeb 230 Pfam PF00072 Response regulator receiver domain 12 121 2.2E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_0463 e5b9cb8d690728ef56564cb3f2227eeb 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 4.2E-25 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_0463 e5b9cb8d690728ef56564cb3f2227eeb 230 SMART SM00448 10 120 4.1E-43 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_0463 e5b9cb8d690728ef56564cb3f2227eeb 230 Gene3D G3DSA:3.40.50.2300 5 129 1.0E-39 T 11-10-2018 TO73_0463 e5b9cb8d690728ef56564cb3f2227eeb 230 SMART SM00862 153 227 2.5E-28 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_0463 e5b9cb8d690728ef56564cb3f2227eeb 230 SUPERFAMILY SSF52172 7 176 1.28E-43 T 11-10-2018 IPR011006 CheY-like superfamily TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 Pfam PF00571 CBS domain 95 142 5.3E-13 T 11-10-2018 IPR000644 CBS domain TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 Pfam PF00571 CBS domain 151 206 3.4E-12 T 11-10-2018 IPR000644 CBS domain TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 462 4.3E-187 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 494 85.334 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 SMART SM00116 98 146 3.1E-14 T 11-10-2018 IPR000644 CBS domain TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 SMART SM00116 160 208 1.6E-11 T 11-10-2018 IPR000644 CBS domain TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 SMART SM01240 9 481 0.0 T 11-10-2018 TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 PIRSF PIRSF000130 1 494 4.4E-208 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 SUPERFAMILY SSF51412 5 485 6.02E-129 T 11-10-2018 TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 481 5.5E-162 T 11-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 Gene3D G3DSA:3.20.20.70 1 494 2.4E-220 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 11-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TO73_1961 5f39f94a7d1be61b0496d4c7a546bf2a 494 SUPERFAMILY SSF54631 79 205 1.71E-31 T 11-10-2018 TO73_1528 fa889cf3a9db7cf64e22a5b87657c330 181 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 7 151 3.1E-33 T 11-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 TO73_1528 fa889cf3a9db7cf64e22a5b87657c330 181 SUPERFAMILY SSF53067 5 103 1.62E-19 T 11-10-2018 TO73_1528 fa889cf3a9db7cf64e22a5b87657c330 181 Gene3D G3DSA:3.30.420.40 6 126 9.6E-25 T 11-10-2018 TO73_1528 fa889cf3a9db7cf64e22a5b87657c330 181 Pfam PF00814 Glycoprotease family 33 132 7.2E-17 T 11-10-2018 IPR000905 Gcp-like domain TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 225 240 1.1E-7 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 196 209 1.1E-7 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 160 179 1.1E-7 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 1.1E-7 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 Gene3D G3DSA:3.40.120.10 6 131 1.9E-19 T 11-10-2018 TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 Gene3D G3DSA:3.40.120.10 161 245 3.9E-19 T 11-10-2018 TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 SUPERFAMILY SSF53738 143 241 1.06E-17 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 121 8.7E-15 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 SUPERFAMILY SSF53738 8 125 1.06E-17 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0641 577c700a3e358c42d9433a9f6e12cded 297 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 143 242 1.8E-17 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_1150 15166e90223a5bca828c2e1abb7b31c7 284 Pfam PF01040 UbiA prenyltransferase family 20 263 1.4E-52 T 11-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TO73_1150 15166e90223a5bca828c2e1abb7b31c7 284 Gene3D G3DSA:1.20.120.1780 163 284 1.6E-34 T 11-10-2018 TO73_1150 15166e90223a5bca828c2e1abb7b31c7 284 Gene3D G3DSA:1.10.357.140 10 162 1.2E-50 T 11-10-2018 TO73_1150 15166e90223a5bca828c2e1abb7b31c7 284 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 3 282 4.8E-103 T 11-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related TO73_1829 b8d17bd6adab385da77914e823fcff33 418 Pfam PF02754 Cysteine-rich domain 309 393 3.7E-18 T 11-10-2018 IPR004017 Cysteine-rich domain TO73_1829 b8d17bd6adab385da77914e823fcff33 418 Pfam PF02754 Cysteine-rich domain 184 260 1.7E-14 T 11-10-2018 IPR004017 Cysteine-rich domain TO73_1829 b8d17bd6adab385da77914e823fcff33 418 Pfam PF13183 4Fe-4S dicluster domain 21 88 8.1E-11 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_1829 b8d17bd6adab385da77914e823fcff33 418 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_1829 b8d17bd6adab385da77914e823fcff33 418 PIRSF PIRSF000139 8 416 3.4E-130 T 11-10-2018 TO73_1829 b8d17bd6adab385da77914e823fcff33 418 Gene3D G3DSA:3.30.70.20 1 89 4.4E-7 T 11-10-2018 TO73_1829 b8d17bd6adab385da77914e823fcff33 418 SUPERFAMILY SSF46548 15 98 3.14E-19 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TO73_0364 dad48fa4ec9126a67ea42cba6819e1d3 58 Pfam PF14104 Domain of unknown function (DUF4277) 8 56 1.1E-9 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_1541 e6c5b06ed8cc63bb6153cc2020388ca9 307 SUPERFAMILY SSF52540 3 223 5.87E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1541 e6c5b06ed8cc63bb6153cc2020388ca9 307 Pfam PF00005 ABC transporter 20 162 7.1E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1541 e6c5b06ed8cc63bb6153cc2020388ca9 307 SMART SM00382 28 228 5.0E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1541 e6c5b06ed8cc63bb6153cc2020388ca9 307 Gene3D G3DSA:3.40.50.300 1 226 4.0E-66 T 11-10-2018 TO73_2215 2e87ceea1588a892973cb4483bebf024 64 SUPERFAMILY SSF54786 6 61 8.63E-11 T 11-10-2018 TO73_2215 2e87ceea1588a892973cb4483bebf024 64 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 7 60 8.4E-10 T 11-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TO73_2215 2e87ceea1588a892973cb4483bebf024 64 Gene3D G3DSA:3.30.920.30 5 61 1.9E-8 T 11-10-2018 IPR038570 HicA superfamily TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 SUPERFAMILY SSF50494 40 205 1.17E-32 T 11-10-2018 IPR009003 Peptidase S1, PA clan TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 SUPERFAMILY SSF50156 254 333 1.84E-17 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 Gene3D G3DSA:2.40.10.120 31 212 1.7E-28 T 11-10-2018 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 Pfam PF13365 Trypsin-like peptidase domain 62 195 6.9E-20 T 11-10-2018 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 Gene3D G3DSA:2.30.42.10 231 331 3.1E-23 T 11-10-2018 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 Pfam PF13180 PDZ domain 255 326 2.7E-11 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 PRINTS PR00834 HtrA/DegQ protease family signature 70 82 5.4E-13 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 PRINTS PR00834 HtrA/DegQ protease family signature 132 156 5.4E-13 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 PRINTS PR00834 HtrA/DegQ protease family signature 166 183 5.4E-13 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 PRINTS PR00834 HtrA/DegQ protease family signature 278 290 5.4E-13 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 PRINTS PR00834 HtrA/DegQ protease family signature 91 111 5.4E-13 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 PRINTS PR00834 HtrA/DegQ protease family signature 188 205 5.4E-13 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1715 bc3e4b3f46b47ea0447330b5badecacb 335 SMART SM00228 232 320 9.7E-7 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_1878 e224903370e2009eb80678659733ac4c 952 Gene3D G3DSA:3.40.50.300 617 937 1.6E-145 T 11-10-2018 TO73_1878 e224903370e2009eb80678659733ac4c 952 Gene3D G3DSA:3.30.190.20 130 244 4.7E-246 T 11-10-2018 TO73_1878 e224903370e2009eb80678659733ac4c 952 Pfam PF00005 ABC transporter 626 656 2.5E-5 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1878 e224903370e2009eb80678659733ac4c 952 SUPERFAMILY SSF52540 618 912 1.56E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1878 e224903370e2009eb80678659733ac4c 952 Gene3D G3DSA:1.20.1580.10 695 832 1.6E-145 T 11-10-2018 TO73_1878 e224903370e2009eb80678659733ac4c 952 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1878 e224903370e2009eb80678659733ac4c 952 Gene3D G3DSA:1.20.1580.10 90 496 4.7E-246 T 11-10-2018 TO73_1878 e224903370e2009eb80678659733ac4c 952 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 927 0.0 T 11-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 TO73_1878 e224903370e2009eb80678659733ac4c 952 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 941 23.026 T 11-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 TO73_1878 e224903370e2009eb80678659733ac4c 952 SUPERFAMILY SSF52540 7 573 9.14E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1878 e224903370e2009eb80678659733ac4c 952 ProSitePatterns PS00211 ABC transporters family signature. 832 846 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1878 e224903370e2009eb80678659733ac4c 952 Gene3D G3DSA:3.40.50.300 5 598 4.7E-246 T 11-10-2018 TO73_1878 e224903370e2009eb80678659733ac4c 952 Gene3D G3DSA:1.10.8.280 287 405 4.7E-246 T 11-10-2018 TO73_1878 e224903370e2009eb80678659733ac4c 952 SMART SM00382 635 924 5.2E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1878 e224903370e2009eb80678659733ac4c 952 SMART SM00382 23 231 1.1 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0496 55c7f6df73ea2518871dd03bee486f3b 251 SUPERFAMILY SSF81606 6 250 2.62E-51 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TO73_0496 55c7f6df73ea2518871dd03bee486f3b 251 SMART SM00331 12 250 1.4E-20 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TO73_0496 55c7f6df73ea2518871dd03bee486f3b 251 Pfam PF13672 Protein phosphatase 2C 13 227 3.9E-16 T 11-10-2018 TO73_0496 55c7f6df73ea2518871dd03bee486f3b 251 Gene3D G3DSA:3.60.40.10 1 251 1.6E-53 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TO73_0496 55c7f6df73ea2518871dd03bee486f3b 251 SMART SM00332 1 248 9.5E-13 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TO73_0105 3f096e3e4ee9ed1a8c8707ede7ebebce 333 SMART SM00478 36 178 3.4E-40 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TO73_0105 3f096e3e4ee9ed1a8c8707ede7ebebce 333 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 180 196 - T 11-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TO73_0105 3f096e3e4ee9ed1a8c8707ede7ebebce 333 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 32 157 3.7E-16 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TO73_0105 3f096e3e4ee9ed1a8c8707ede7ebebce 333 SUPERFAMILY SSF48150 3 200 2.98E-67 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TO73_0105 3f096e3e4ee9ed1a8c8707ede7ebebce 333 SMART SM00525 179 199 1.3E-4 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TO73_0105 3f096e3e4ee9ed1a8c8707ede7ebebce 333 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 180 196 3.4E-4 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TO73_0105 3f096e3e4ee9ed1a8c8707ede7ebebce 333 Gene3D G3DSA:1.10.340.30 18 124 5.1E-76 T 11-10-2018 TO73_0105 3f096e3e4ee9ed1a8c8707ede7ebebce 333 Gene3D G3DSA:1.10.1670.10 7 198 5.1E-76 T 11-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TO73_2828 556bd2d883e26b31451cc09baef90f6e 343 SUPERFAMILY SSF81345 7 335 2.35E-78 T 11-10-2018 IPR037294 ABC transporter, BtuC-like TO73_2828 556bd2d883e26b31451cc09baef90f6e 343 Pfam PF01032 FecCD transport family 24 335 7.2E-85 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TO73_2828 556bd2d883e26b31451cc09baef90f6e 343 Gene3D G3DSA:1.10.3470.10 11 340 2.3E-96 T 11-10-2018 IPR037294 ABC transporter, BtuC-like TO73_1827 e88376339cfc292fc66a1bafb46fbc61 458 Gene3D G3DSA:3.30.465.10 91 211 1.1E-34 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TO73_1827 e88376339cfc292fc66a1bafb46fbc61 458 Pfam PF01565 FAD binding domain 37 176 5.6E-43 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TO73_1827 e88376339cfc292fc66a1bafb46fbc61 458 Gene3D G3DSA:3.30.70.2190 212 324 8.4E-6 T 11-10-2018 TO73_1827 e88376339cfc292fc66a1bafb46fbc61 458 Gene3D G3DSA:1.10.45.10 412 452 1.7E-9 T 11-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TO73_1827 e88376339cfc292fc66a1bafb46fbc61 458 Pfam PF02913 FAD linked oxidases, C-terminal domain 212 451 2.3E-67 T 11-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TO73_1827 e88376339cfc292fc66a1bafb46fbc61 458 Gene3D G3DSA:3.30.70.2740 330 411 7.3E-9 T 11-10-2018 TO73_1827 e88376339cfc292fc66a1bafb46fbc61 458 SUPERFAMILY SSF55103 215 454 3.11E-68 T 11-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TO73_1827 e88376339cfc292fc66a1bafb46fbc61 458 SUPERFAMILY SSF56176 3 212 1.96E-68 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TO73_1827 e88376339cfc292fc66a1bafb46fbc61 458 Gene3D G3DSA:3.30.43.10 2 89 2.8E-26 T 11-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Pfam PF02867 Ribonucleotide reductase, barrel domain 274 1109 7.4E-91 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Pfam PF14890 Intein splicing domain 1168 1520 6.6E-13 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1501 1521 1.3E-4 T 11-10-2018 IPR030934 Intein C-terminal splicing region TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 829 851 1.0E-5 T 11-10-2018 IPR030934 Intein C-terminal splicing region TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SUPERFAMILY SSF51998 1509 1576 6.41E-11 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SUPERFAMILY SSF51294 446 850 1.57E-37 T 11-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Gene3D G3DSA:3.20.70.20 2 172 1.1E-22 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Gene3D G3DSA:3.20.70.20 1482 1567 4.1E-17 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Gene3D G3DSA:3.20.70.20 847 1121 4.3E-85 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SUPERFAMILY SSF55608 1331 1398 3.8E-6 T 11-10-2018 IPR027434 Homing endonuclease TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Gene3D G3DSA:2.170.16.10 792 846 2.0E-6 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Gene3D G3DSA:3.20.70.20 204 447 8.0E-52 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Pfam PF02867 Ribonucleotide reductase, barrel domain 1521 1551 1.7E-5 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 447 532 2.1E-8 T 11-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 6 77 3.7E-10 T 11-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SMART SM00305 1481 1526 4.6E-6 T 11-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SMART SM00305 810 856 3.1E-6 T 11-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Gene3D G3DSA:2.170.16.10 448 564 4.9E-17 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Pfam PF14890 Intein splicing domain 497 850 3.3E-18 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SUPERFAMILY SSF51998 206 1109 1.3E-100 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SUPERFAMILY SSF55608 679 803 5.95E-14 T 11-10-2018 IPR027434 Homing endonuclease TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Gene3D G3DSA:2.170.16.10 1122 1241 7.0E-9 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 PRINTS PR00379 Intein signature 519 532 1.0E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 PRINTS PR00379 Intein signature 728 743 1.0E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 PRINTS PR00379 Intein signature 696 708 1.0E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 PRINTS PR00379 Intein signature 827 844 1.0E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 PRINTS PR00379 Intein signature 845 854 1.0E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 PRINTS PR00379 Intein signature 601 613 1.0E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SUPERFAMILY SSF48168 29 76 6.02E-5 T 11-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Gene3D G3DSA:3.10.28.10 599 756 4.3E-27 T 11-10-2018 IPR027434 Homing endonuclease TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Gene3D G3DSA:3.10.28.10 1248 1405 7.3E-22 T 11-10-2018 IPR027434 Homing endonuclease TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SUPERFAMILY SSF51294 1120 1520 6.44E-31 T 11-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Pfam PF02867 Ribonucleotide reductase, barrel domain 206 267 2.5E-6 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SMART SM00306 445 552 1.1E-19 T 11-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SMART SM00306 1119 1216 6.7E-5 T 11-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 SUPERFAMILY SSF51998 79 151 9.61E-8 T 11-10-2018 TO73_0472 f5d3358f8641c49aa511e9d31bcb1cf9 1768 Pfam PF14528 LAGLIDADG-like domain 696 789 1.5E-18 T 11-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TO73_2716 9d4cf9afed13433ddbb9b42fd29a5117 814 SUPERFAMILY SSF52540 107 551 6.37E-35 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2716 9d4cf9afed13433ddbb9b42fd29a5117 814 Gene3D G3DSA:3.40.50.300 343 557 1.3E-24 T 11-10-2018 TO73_2716 9d4cf9afed13433ddbb9b42fd29a5117 814 Pfam PF12696 TraM recognition site of TraD and TraG 411 532 3.1E-20 T 11-10-2018 IPR032689 TraD/TraG, TraM recognition site TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 6 430 44.889 T 11-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 Gene3D G3DSA:3.40.50.620 8 223 1.8E-78 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 Gene3D G3DSA:3.10.290.10 352 430 3.9E-32 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 SUPERFAMILY SSF55174 353 430 3.27E-18 T 11-10-2018 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 11 430 1.4E-96 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 Pfam PF00579 tRNA synthetases class I (W and Y) 35 293 2.9E-63 T 11-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 Gene3D G3DSA:1.10.240.10 224 340 3.0E-36 T 11-10-2018 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 SUPERFAMILY SSF52374 8 300 5.63E-83 T 11-10-2018 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 50 72 1.2E-24 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 1.2E-24 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 167 182 1.2E-24 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TO73_0534 f79f4aa9b33f31944d104c84d571f8db 433 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 184 206 1.2E-24 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 ProSitePatterns PS00450 Aconitase family signature 1. 284 300 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 Gene3D G3DSA:3.30.499.10 265 415 3.4E-59 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 411 47.078 T 11-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 Gene3D G3DSA:3.30.499.20 4 262 1.5E-75 T 11-10-2018 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 ProSitePatterns PS01244 Aconitase family signature 2. 344 357 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 Pfam PF00330 Aconitase family (aconitate hydratase) 29 403 1.0E-83 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 PRINTS PR00415 Aconitase family signature 344 357 2.3E-13 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 PRINTS PR00415 Aconitase family signature 288 299 2.3E-13 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 PRINTS PR00415 Aconitase family signature 124 139 2.3E-13 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 PRINTS PR00415 Aconitase family signature 110 123 2.3E-13 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 409 7.3E-176 T 11-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 410 1.2E-187 T 11-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TO73_0094 f9f313b66be0e07de04bcde2ec23802d 417 SUPERFAMILY SSF53732 1 412 8.76E-129 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TO73_0843 0f3a04bdfc6e960d0d3196ad095ef02f 127 Gene3D G3DSA:1.10.1510.10 1 67 6.8E-6 T 11-10-2018 TO73_0843 0f3a04bdfc6e960d0d3196ad095ef02f 127 Pfam PF09424 Yqey-like protein 4 51 2.0E-5 T 11-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 TO73_0843 0f3a04bdfc6e960d0d3196ad095ef02f 127 Pfam PF09424 Yqey-like protein 61 116 1.1E-5 T 11-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 TO73_0843 0f3a04bdfc6e960d0d3196ad095ef02f 127 SUPERFAMILY SSF89095 2 123 1.1E-15 T 11-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TO73_2025 dc79954d0d5ed9a2dae66e7ec5fd6039 390 SMART SM00788 1 385 5.3E-177 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TO73_2025 dc79954d0d5ed9a2dae66e7ec5fd6039 390 SUPERFAMILY SSF52540 1 384 2.34E-128 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2025 dc79954d0d5ed9a2dae66e7ec5fd6039 390 Gene3D G3DSA:3.40.440.10 1 230 9.6E-77 T 11-10-2018 TO73_2025 dc79954d0d5ed9a2dae66e7ec5fd6039 390 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 1 383 5.7E-125 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TO73_2025 dc79954d0d5ed9a2dae66e7ec5fd6039 390 Gene3D G3DSA:3.90.170.10 237 386 9.1E-52 T 11-10-2018 TO73_2025 dc79954d0d5ed9a2dae66e7ec5fd6039 390 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 390 143.144 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TO73_2025 dc79954d0d5ed9a2dae66e7ec5fd6039 390 Gene3D G3DSA:1.10.300.10 81 171 9.6E-77 T 11-10-2018 TO73_2025 dc79954d0d5ed9a2dae66e7ec5fd6039 390 Pfam PF00709 Adenylosuccinate synthetase 1 383 2.5E-139 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 Gene3D G3DSA:3.30.70.100 4 68 4.9E-18 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 Gene3D G3DSA:3.30.70.100 69 135 2.1E-22 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 SUPERFAMILY SSF55008 70 137 3.4E-21 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 192 781 3.2E-178 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 Pfam PF00702 haloacid dehalogenase-like hydrolase 475 685 5.1E-48 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 SUPERFAMILY SSF56784 476 778 2.04E-60 T 11-10-2018 IPR036412 HAD-like superfamily TO73_0284 107701e49abb4baf813a72f2c51df0de 791 SUPERFAMILY SSF81653 281 378 3.27E-29 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 SUPERFAMILY SSF55008 3 69 1.7E-17 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 Pfam PF00403 Heavy-metal-associated domain 8 65 5.8E-11 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 Pfam PF00403 Heavy-metal-associated domain 73 133 1.5E-17 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 SUPERFAMILY SSF81665 228 767 4.05E-14 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 ProSitePatterns PS01047 Heavy-metal-associated domain. 75 104 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 Gene3D G3DSA:3.40.1110.10 489 603 9.9E-88 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 ProSitePatterns PS01229 Hypothetical cof family signature 2. 671 693 - T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 Pfam PF00122 E1-E2 ATPase 279 457 3.2E-58 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 211 780 3.7E-187 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 Gene3D G3DSA:2.70.150.20 266 382 8.6E-42 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 2.4E-28 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 478 492 2.4E-28 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 596 607 2.4E-28 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 671 690 2.4E-28 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 618 628 2.4E-28 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 694 706 2.4E-28 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 480 486 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00943 Copper-transporting ATPase signature 268 286 3.0E-13 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00943 Copper-transporting ATPase signature 648 665 3.0E-13 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00943 Copper-transporting ATPase signature 248 267 3.0E-13 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00943 Copper-transporting ATPase signature 85 99 3.0E-13 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00943 Copper-transporting ATPase signature 401 415 3.0E-13 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 PRINTS PR00943 Copper-transporting ATPase signature 196 215 3.0E-13 T 11-10-2018 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 Gene3D G3DSA:3.40.50.1000 473 721 9.9E-88 T 11-10-2018 IPR023214 HAD superfamily TO73_0284 107701e49abb4baf813a72f2c51df0de 791 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 5 66 1.8E-9 T 11-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 71 133 5.5E-18 T 11-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TO73_0284 107701e49abb4baf813a72f2c51df0de 791 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 250 764 5.7E-94 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TO73_1593 f6afc16e02a45665b0a46ab8b35cdf24 478 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1593 f6afc16e02a45665b0a46ab8b35cdf24 478 SUPERFAMILY SSF47917 372 426 5.49E-6 T 11-10-2018 TO73_1593 f6afc16e02a45665b0a46ab8b35cdf24 478 SUPERFAMILY SSF52540 82 365 2.87E-83 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1593 f6afc16e02a45665b0a46ab8b35cdf24 478 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 11 68 3.6E-8 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1593 f6afc16e02a45665b0a46ab8b35cdf24 478 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 134 359 3.5E-66 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1593 f6afc16e02a45665b0a46ab8b35cdf24 478 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 5 467 58.979 T 11-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1593 f6afc16e02a45665b0a46ab8b35cdf24 478 PIRSF PIRSF039114 1 472 2.7E-241 T 11-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1593 f6afc16e02a45665b0a46ab8b35cdf24 478 Gene3D G3DSA:3.40.50.12240 1 464 2.3E-189 T 11-10-2018 TO73_1686 7b692c25cd64e806b07e0f29b81efbf5 336 SUPERFAMILY SSF50156 89 182 3.02E-17 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 TO73_1686 7b692c25cd64e806b07e0f29b81efbf5 336 Gene3D G3DSA:2.30.42.10 92 183 7.4E-16 T 11-10-2018 TO73_1686 7b692c25cd64e806b07e0f29b81efbf5 336 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 119 163 4.7E-7 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_1686 7b692c25cd64e806b07e0f29b81efbf5 336 Pfam PF02163 Peptidase family M50 6 321 3.8E-53 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TO73_1686 7b692c25cd64e806b07e0f29b81efbf5 336 SMART SM00228 105 174 2.6E-9 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 SMART SM00382 98 260 2.8E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 Gene3D G3DSA:3.30.50.30 2 46 2.7E-8 T 11-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 1 392 48.387 T 11-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 SMART SM01086 295 386 4.1E-30 T 11-10-2018 IPR019489 Clp ATPase, C-terminal TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 Pfam PF06689 ClpX C4-type zinc finger 7 45 2.0E-11 T 11-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 7 376 9.3E-167 T 11-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 Gene3D G3DSA:1.10.8.60 294 395 1.8E-35 T 11-10-2018 TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 Pfam PF07724 AAA domain (Cdc48 subfamily) 99 288 3.3E-48 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 SMART SM00994 5 46 5.4E-13 T 11-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 SUPERFAMILY SSF57716 6 43 7.98E-6 T 11-10-2018 TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 295 368 1.7E-15 T 11-10-2018 IPR019489 Clp ATPase, C-terminal TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 SUPERFAMILY SSF52540 55 384 1.07E-68 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1136 bffbff2540b3e0b41b77e6bfa76804dd 396 Gene3D G3DSA:3.40.50.300 51 293 3.5E-99 T 11-10-2018 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 344 372 8.0E-53 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 552 564 8.0E-53 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 377 400 8.0E-53 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 482 510 8.0E-53 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 525 538 8.0E-53 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Gene3D G3DSA:3.10.20.30 1 63 2.2E-18 T 11-10-2018 IPR012675 Beta-grasp domain superfamily TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 228 1.4E-12 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 SUPERFAMILY SSF55186 62 250 9.16E-54 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Gene3D G3DSA:3.30.930.10 235 550 1.7E-119 T 11-10-2018 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 336 546 1.5E-41 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 65 652 35.425 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 71 645 1.5E-209 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Gene3D G3DSA:3.40.50.800 551 657 8.0E-32 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Gene3D G3DSA:3.30.54.20 136 195 1.4E-55 T 11-10-2018 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Pfam PF02824 TGS domain 1 60 3.9E-17 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Pfam PF03129 Anticodon binding domain 559 639 5.5E-22 T 11-10-2018 IPR004154 Anticodon-binding TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 SUPERFAMILY SSF81271 2 60 3.71E-14 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 SMART SM00863 174 228 3.7E-22 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 SUPERFAMILY SSF52954 548 649 1.66E-29 T 11-10-2018 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 SUPERFAMILY SSF55681 252 544 1.67E-92 T 11-10-2018 TO73_2249 bb9befbc1fe4db7df0d85138f5b1007e 660 Gene3D G3DSA:3.30.980.10 69 231 1.4E-55 T 11-10-2018 TO73_0740 50c3a16e66e962f08fb0ce01b709db53 34 Pfam PF08113 Cytochrome c oxidase subunit IIa family 2 34 1.7E-16 T 11-10-2018 IPR012538 Cytochrome c oxidase polypeptide 2A KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TO73_0740 50c3a16e66e962f08fb0ce01b709db53 34 SUPERFAMILY SSF81473 2 34 1.96E-11 T 11-10-2018 IPR036246 Cytochrome c oxidase polypeptide 2A, ba3 type KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TO73_1952 f99d8ef8431967fbe43516bd68f5e128 210 SUPERFAMILY SSF144091 11 208 1.02E-47 T 11-10-2018 TO73_1952 f99d8ef8431967fbe43516bd68f5e128 210 Gene3D G3DSA:1.20.1540.10 8 207 1.5E-35 T 11-10-2018 IPR035952 Rhomboid-like superfamily TO73_1952 f99d8ef8431967fbe43516bd68f5e128 210 Pfam PF01694 Rhomboid family 56 207 2.6E-43 T 11-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TO73_0506 4e31f43c3e957f019be8afc4f54deb3f 549 TIGRFAM TIGR00337 PyrG: CTP synthase 12 541 8.3E-232 T 11-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TO73_0506 4e31f43c3e957f019be8afc4f54deb3f 549 Gene3D G3DSA:3.40.50.300 2 295 4.8E-134 T 11-10-2018 TO73_0506 4e31f43c3e957f019be8afc4f54deb3f 549 Pfam PF00117 Glutamine amidotransferase class-I 311 541 5.7E-49 T 11-10-2018 IPR017926 Glutamine amidotransferase TO73_0506 4e31f43c3e957f019be8afc4f54deb3f 549 Gene3D G3DSA:3.40.50.880 296 547 8.2E-105 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0506 4e31f43c3e957f019be8afc4f54deb3f 549 SUPERFAMILY SSF52540 11 278 1.24E-117 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0506 4e31f43c3e957f019be8afc4f54deb3f 549 Hamap MF_01227 CTP synthase [pyrG]. 11 546 51.638 T 11-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TO73_0506 4e31f43c3e957f019be8afc4f54deb3f 549 Pfam PF06418 CTP synthase N-terminus 12 276 8.1E-123 T 11-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TO73_0506 4e31f43c3e957f019be8afc4f54deb3f 549 SUPERFAMILY SSF52317 299 545 1.52E-77 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 7.2E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 514 7.2E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 495 7.2E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 SUPERFAMILY SSF55781 180 322 2.03E-8 T 11-10-2018 TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 427 514 1.6E-9 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 Gene3D G3DSA:3.30.450.40 170 314 2.2E-8 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 SMART SM00387 422 515 2.4E-10 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 SUPERFAMILY SSF55874 389 514 4.45E-22 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 Gene3D G3DSA:3.30.565.10 390 515 2.2E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1306 b84792f71b51d3c0a4e5ff9fdea99fc5 515 Pfam PF07730 Histidine kinase 318 384 4.3E-20 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TO73_2036 de44edf67985ea4856628c35eec58304 421 SUPERFAMILY SSF53335 23 220 7.72E-52 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2036 de44edf67985ea4856628c35eec58304 421 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 102 108 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TO73_2036 de44edf67985ea4856628c35eec58304 421 Pfam PF07669 Eco57I restriction-modification methylase 99 210 1.2E-6 T 11-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 TO73_2036 de44edf67985ea4856628c35eec58304 421 PIRSF PIRSF037236 1 421 2.2E-292 T 11-10-2018 IPR021188 N6 adenine-specific DNA methyltransferase, TaqI class TO73_2036 de44edf67985ea4856628c35eec58304 421 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 141 165 1.5E-20 T 11-10-2018 TO73_2036 de44edf67985ea4856628c35eec58304 421 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 43 57 1.5E-20 T 11-10-2018 TO73_2036 de44edf67985ea4856628c35eec58304 421 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 19 35 1.5E-20 T 11-10-2018 TO73_2036 de44edf67985ea4856628c35eec58304 421 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 99 111 1.5E-20 T 11-10-2018 TO73_2036 de44edf67985ea4856628c35eec58304 421 Gene3D G3DSA:3.40.50.150 22 243 3.9E-62 T 11-10-2018 TO73_2036 de44edf67985ea4856628c35eec58304 421 Gene3D G3DSA:3.90.220.10 244 412 1.2E-91 T 11-10-2018 IPR023135 N6 adenine-specific DNA methyltransferase, TaqI class, C-terminal TO73_2036 de44edf67985ea4856628c35eec58304 421 Pfam PF12950 TaqI-like C-terminal specificity domain 291 405 8.7E-15 T 11-10-2018 IPR025931 TaqI-like C-terminal specificity domain TO73_2036 de44edf67985ea4856628c35eec58304 421 SUPERFAMILY SSF116734 244 412 9.81E-83 T 11-10-2018 TO73_0024 124683553d9c159e1c44fa606783c60f 183 SUPERFAMILY SSF109604 17 154 9.07E-18 T 11-10-2018 TO73_0024 124683553d9c159e1c44fa606783c60f 183 SMART SM00471 16 121 0.0025 T 11-10-2018 IPR003607 HD/PDEase domain TO73_0024 124683553d9c159e1c44fa606783c60f 183 Gene3D G3DSA:1.10.3210.10 13 157 1.1E-8 T 11-10-2018 TO73_0024 124683553d9c159e1c44fa606783c60f 183 Pfam PF01966 HD domain 22 88 5.3E-7 T 11-10-2018 IPR006674 HD domain TO73_0024 124683553d9c159e1c44fa606783c60f 183 TIGRFAM TIGR00277 HDIG: HDIG domain 18 88 3.0E-8 T 11-10-2018 IPR006675 HDIG domain TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 Gene3D G3DSA:2.160.20.10 520 773 1.5E-10 T 11-10-2018 IPR012334 Pectin lyase fold TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 Pfam PF13229 Right handed beta helix region 498 700 7.6E-10 T 11-10-2018 IPR039448 Right handed beta helix domain TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 SUPERFAMILY SSF117074 843 942 6.28E-6 T 11-10-2018 TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 Gene3D G3DSA:2.60.40.10 872 984 9.2E-10 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1265 1294 6.6E-6 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 57 98 2.4E-13 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 Gene3D G3DSA:2.60.40.740 38 202 2.4E-5 T 11-10-2018 TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 SUPERFAMILY SSF117074 204 275 5.23E-6 T 11-10-2018 TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 Pfam PF01345 Domain of unknown function DUF11 45 177 2.3E-13 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 SMART SM00710 963 988 5400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 SMART SM00710 503 531 1200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 SMART SM00710 591 624 3000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 SMART SM00710 723 745 2400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 SMART SM00710 690 718 170.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 SMART SM00710 666 688 0.93 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 Gene3D G3DSA:2.60.40.10 203 363 4.0E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 Gene3D G3DSA:2.60.40.10 985 1106 3.2E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0966 8eafad3386fe4ccbdd2094d592c78870 1356 SUPERFAMILY SSF51126 492 759 3.77E-13 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor TO73_1626 9c80c3125be4822ca6330c41d622ee61 289 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 28 155 1.0E-26 T 11-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TO73_1626 9c80c3125be4822ca6330c41d622ee61 289 SUPERFAMILY SSF53850 22 287 2.09E-43 T 11-10-2018 TO73_1626 9c80c3125be4822ca6330c41d622ee61 289 Pfam PF13531 Bacterial extracellular solute-binding protein 23 284 1.7E-35 T 11-10-2018 TO73_2847 a2bb76c72f03def3abf7f09f49649545 111 Gene3D G3DSA:1.10.10.10 23 86 5.8E-10 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2847 a2bb76c72f03def3abf7f09f49649545 111 Pfam PF04255 Protein of unknown function (DUF433) 26 71 1.1E-9 T 11-10-2018 IPR007367 Protein of unknown function DUF433 TO73_2847 a2bb76c72f03def3abf7f09f49649545 111 SUPERFAMILY SSF46689 22 82 3.76E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_0917 a2bb76c72f03def3abf7f09f49649545 111 Gene3D G3DSA:1.10.10.10 23 86 5.8E-10 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0917 a2bb76c72f03def3abf7f09f49649545 111 Pfam PF04255 Protein of unknown function (DUF433) 26 71 1.1E-9 T 11-10-2018 IPR007367 Protein of unknown function DUF433 TO73_0917 a2bb76c72f03def3abf7f09f49649545 111 SUPERFAMILY SSF46689 22 82 3.76E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_0103 3b09e94e02c8a1c8b5eb1f9f067fffa8 281 SUPERFAMILY SSF52402 10 262 1.87E-67 T 11-10-2018 TO73_0103 3b09e94e02c8a1c8b5eb1f9f067fffa8 281 Gene3D G3DSA:3.40.50.620 15 263 1.6E-70 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0103 3b09e94e02c8a1c8b5eb1f9f067fffa8 281 TIGRFAM TIGR00552 nadE: NAD+ synthetase 24 260 9.2E-60 T 11-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TO73_0103 3b09e94e02c8a1c8b5eb1f9f067fffa8 281 Pfam PF02540 NAD synthase 24 259 4.3E-63 T 11-10-2018 IPR022310 NAD/GMP synthase TO73_0901 838e92574b38570a22b23bd2f62339dc 223 SUPERFAMILY SSF53850 8 158 1.95E-12 T 11-10-2018 TO73_0901 838e92574b38570a22b23bd2f62339dc 223 Pfam PF16868 NMT1-like family 59 156 1.0E-12 T 11-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TO73_0901 838e92574b38570a22b23bd2f62339dc 223 Gene3D G3DSA:3.40.190.10 91 156 8.0E-19 T 11-10-2018 TO73_0901 838e92574b38570a22b23bd2f62339dc 223 Gene3D G3DSA:3.40.190.10 4 90 8.0E-19 T 11-10-2018 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 7 613 35.288 T 11-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 SUPERFAMILY SSF140990 416 608 2.49E-63 T 11-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 ProSitePatterns PS00674 AAA-protein family signature. 304 322 - T 11-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 Gene3D G3DSA:3.40.50.300 151 333 2.0E-69 T 11-10-2018 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 Pfam PF01434 Peptidase family M41 396 602 1.3E-68 T 11-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 114 603 7.9E-216 T 11-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 Gene3D G3DSA:1.20.58.760 416 614 4.9E-70 T 11-10-2018 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 Gene3D G3DSA:1.10.8.60 335 412 4.3E-27 T 11-10-2018 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 SUPERFAMILY SSF52540 157 405 6.63E-76 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1795 53b3d380a909580ad60cd73056a974b9 615 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 201 333 3.6E-45 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_1795 53b3d380a909580ad60cd73056a974b9 615 SMART SM00382 197 336 3.6E-25 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1415 fda596a49be04557cf46ae0333e6d24c 134 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 26 1.1E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1415 fda596a49be04557cf46ae0333e6d24c 134 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 3.8E-10 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1415 fda596a49be04557cf46ae0333e6d24c 134 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1415 fda596a49be04557cf46ae0333e6d24c 134 SUPERFAMILY SSF54523 7 104 2.2E-17 T 11-10-2018 TO73_1415 fda596a49be04557cf46ae0333e6d24c 134 Gene3D G3DSA:3.30.700.10 7 133 3.2E-20 T 11-10-2018 TO73_1643 9790e31a546992671f89186fc43b0b9f 467 SUPERFAMILY SSF51905 2 450 2.0E-43 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1643 9790e31a546992671f89186fc43b0b9f 467 Gene3D G3DSA:3.50.50.60 1 84 5.7E-20 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1643 9790e31a546992671f89186fc43b0b9f 467 Pfam PF01593 Flavin containing amine oxidoreductase 10 287 2.4E-16 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TO73_0470 d972b0e60d356c2688503902693589c5 263 Gene3D G3DSA:3.40.190.80 145 262 2.0E-36 T 11-10-2018 TO73_0470 d972b0e60d356c2688503902693589c5 263 Pfam PF00459 Inositol monophosphatase family 35 260 7.0E-60 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TO73_0470 d972b0e60d356c2688503902693589c5 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 8.3E-49 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TO73_0470 d972b0e60d356c2688503902693589c5 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 8.3E-49 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TO73_0470 d972b0e60d356c2688503902693589c5 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 8.3E-49 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TO73_0470 d972b0e60d356c2688503902693589c5 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 8.3E-49 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TO73_0470 d972b0e60d356c2688503902693589c5 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 8.3E-49 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TO73_0470 d972b0e60d356c2688503902693589c5 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 8.3E-49 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TO73_0470 d972b0e60d356c2688503902693589c5 263 SUPERFAMILY SSF56655 8 260 1.44E-76 T 11-10-2018 TO73_0470 d972b0e60d356c2688503902693589c5 263 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 11-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TO73_0470 d972b0e60d356c2688503902693589c5 263 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 11-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 TO73_0470 d972b0e60d356c2688503902693589c5 263 Gene3D G3DSA:3.30.540.10 7 143 2.7E-38 T 11-10-2018 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 SUPERFAMILY SSF55681 105 575 8.5E-108 T 11-10-2018 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 SUPERFAMILY SSF50249 1 103 1.05E-29 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 Gene3D G3DSA:2.40.50.140 1 106 2.2E-31 T 11-10-2018 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 Pfam PF00152 tRNA synthetases class II (D, K and N) 124 551 5.6E-109 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 SUPERFAMILY SSF55261 295 413 8.72E-32 T 11-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 Gene3D G3DSA:3.30.1360.30 278 415 4.0E-188 T 11-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 Gene3D G3DSA:3.30.930.10 140 573 4.0E-188 T 11-10-2018 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 577 2.9E-216 T 11-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 Pfam PF02938 GAD domain 317 400 6.9E-22 T 11-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 512 526 1.4E-26 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 213 226 1.4E-26 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 468 484 1.4E-26 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 208 1.4E-26 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 578 33.968 T 11-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 TO73_1631 c3517f4633a79e4d48cac0fabd4b3563 581 Pfam PF01336 OB-fold nucleic acid binding domain 19 99 1.0E-13 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TO73_1031 696a138c5a88100df3868aab6db36ffb 438 Gene3D G3DSA:3.90.1150.10 9 429 9.4E-142 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1031 696a138c5a88100df3868aab6db36ffb 438 SUPERFAMILY SSF53383 9 432 4.68E-124 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1031 696a138c5a88100df3868aab6db36ffb 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_1031 696a138c5a88100df3868aab6db36ffb 438 Pfam PF00202 Aminotransferase class-III 25 430 1.4E-95 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_1031 696a138c5a88100df3868aab6db36ffb 438 Gene3D G3DSA:3.40.640.10 58 324 9.4E-142 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1264 815f7069e931538045d76c572eafb7df 219 Gene3D G3DSA:1.10.10.10 5 141 7.3E-54 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1264 815f7069e931538045d76c572eafb7df 219 SUPERFAMILY SSF50037 133 217 2.22E-9 T 11-10-2018 IPR008988 Transcriptional repressor, C-terminal TO73_1264 815f7069e931538045d76c572eafb7df 219 Pfam PF04023 FeoA domain 151 217 8.5E-6 T 11-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TO73_1264 815f7069e931538045d76c572eafb7df 219 SUPERFAMILY SSF47979 68 142 1.57E-26 T 11-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TO73_1264 815f7069e931538045d76c572eafb7df 219 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 6 65 1.8E-19 T 11-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 TO73_1264 815f7069e931538045d76c572eafb7df 219 SUPERFAMILY SSF46785 6 66 1.8E-12 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1264 815f7069e931538045d76c572eafb7df 219 SMART SM00529 29 128 1.1E-45 T 11-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 TO73_1264 815f7069e931538045d76c572eafb7df 219 SMART SM00899 148 217 2.5E-6 T 11-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TO73_1264 815f7069e931538045d76c572eafb7df 219 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 68 136 2.5E-29 T 11-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TO73_1727 a1db781351db3841f611b06026101b46 619 SUPERFAMILY SSF50249 518 616 9.79E-36 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1727 a1db781351db3841f611b06026101b46 619 Gene3D G3DSA:3.40.50.620 5 330 2.2E-148 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1727 a1db781351db3841f611b06026101b46 619 SUPERFAMILY SSF47323 349 499 1.55E-35 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1727 a1db781351db3841f611b06026101b46 619 Gene3D G3DSA:2.40.50.140 509 618 6.9E-39 T 11-10-2018 TO73_1727 a1db781351db3841f611b06026101b46 619 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 3 133 1.4E-10 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1727 a1db781351db3841f611b06026101b46 619 Gene3D G3DSA:1.10.730.10 337 500 6.9E-45 T 11-10-2018 TO73_1727 a1db781351db3841f611b06026101b46 619 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 500 45.961 T 11-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TO73_1727 a1db781351db3841f611b06026101b46 619 SUPERFAMILY SSF52374 2 346 3.49E-112 T 11-10-2018 TO73_1727 a1db781351db3841f611b06026101b46 619 Gene3D G3DSA:2.170.220.10 116 226 2.2E-148 T 11-10-2018 TO73_1727 a1db781351db3841f611b06026101b46 619 Pfam PF09334 tRNA synthetases class I (M) 137 360 1.0E-54 T 11-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1727 a1db781351db3841f611b06026101b46 619 Pfam PF01588 Putative tRNA binding domain 525 616 3.7E-31 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TO73_1727 a1db781351db3841f611b06026101b46 619 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 502 618 1.7E-41 T 11-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TO73_1727 a1db781351db3841f611b06026101b46 619 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 5.3E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TO73_1727 a1db781351db3841f611b06026101b46 619 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 5.3E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TO73_1727 a1db781351db3841f611b06026101b46 619 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 5.3E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TO73_1727 a1db781351db3841f611b06026101b46 619 PRINTS PR01041 Methionyl-tRNA synthetase signature 348 359 5.3E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TO73_1727 a1db781351db3841f611b06026101b46 619 PRINTS PR01041 Methionyl-tRNA synthetase signature 255 270 5.3E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TO73_1727 a1db781351db3841f611b06026101b46 619 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 5.3E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 470 7.1E-204 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 SUPERFAMILY SSF52540 410 725 2.19E-52 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 SMART SM00957 5 396 5.4E-269 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 ProSitePatterns PS01312 SecA family signature. 570 585 - T 11-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 Gene3D G3DSA:3.90.1440.10 229 362 4.7E-177 T 11-10-2018 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 SUPERFAMILY SSF52540 5 409 4.59E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 Gene3D G3DSA:3.40.50.300 21 409 4.7E-177 T 11-10-2018 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 Pfam PF01043 SecA preprotein cross-linking domain 232 352 8.0E-39 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 939 19.919 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 SMART SM00958 228 352 5.6E-71 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 Gene3D G3DSA:1.10.3060.10 728 940 4.0E-67 T 11-10-2018 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 Pfam PF07517 SecA DEAD-like domain 6 396 1.5E-122 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 Pfam PF07516 SecA Wing and Scaffold domain 724 936 2.7E-66 T 11-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 SUPERFAMILY SSF81767 227 362 1.57E-43 T 11-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 SUPERFAMILY SSF81886 727 942 2.62E-71 T 11-10-2018 IPR036266 SecA, Wing/Scaffold superfamily TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 PRINTS PR00906 SecA protein signature 60 84 2.5E-68 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 PRINTS PR00906 SecA protein signature 167 187 2.5E-68 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 PRINTS PR00906 SecA protein signature 407 420 2.5E-68 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 PRINTS PR00906 SecA protein signature 114 124 2.5E-68 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 PRINTS PR00906 SecA protein signature 98 112 2.5E-68 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 PRINTS PR00906 SecA protein signature 370 387 2.5E-68 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TO73_1759 ec3d7a6e5b5f4c777324793ddbdc84a3 997 PRINTS PR00906 SecA protein signature 333 355 2.5E-68 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TO73_2356 70125581c27f693b85abe4ca89f08462 186 SUPERFAMILY SSF48452 6 169 3.61E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2356 70125581c27f693b85abe4ca89f08462 186 Pfam PF13432 Tetratricopeptide repeat 35 96 1.3E-7 T 11-10-2018 TO73_2356 70125581c27f693b85abe4ca89f08462 186 Gene3D G3DSA:1.25.40.10 11 185 4.7E-27 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2300 f40b5e1751ec011c8b804cf683ab0634 354 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 211 230 3.0E-9 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_2300 f40b5e1751ec011c8b804cf683ab0634 354 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 267 287 3.0E-9 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_2300 f40b5e1751ec011c8b804cf683ab0634 354 Pfam PF02073 Thermophilic metalloprotease (M29) 4 336 1.9E-63 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_2300 f40b5e1751ec011c8b804cf683ab0634 354 SUPERFAMILY SSF144052 4 354 1.44E-92 T 11-10-2018 TO73_2092 4e101873393573796144b4963d83c044 310 Gene3D G3DSA:3.40.50.2020 8 297 2.1E-114 T 11-10-2018 TO73_2092 4e101873393573796144b4963d83c044 310 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 5 310 43.491 T 11-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TO73_2092 4e101873393573796144b4963d83c044 310 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 309 5.1E-23 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TO73_2092 4e101873393573796144b4963d83c044 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 310 3.3E-116 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TO73_2092 4e101873393573796144b4963d83c044 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 121 9.9E-43 T 11-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TO73_2092 4e101873393573796144b4963d83c044 310 SMART SM01400 5 121 5.0E-66 T 11-10-2018 TO73_2092 4e101873393573796144b4963d83c044 310 Gene3D G3DSA:3.40.50.2020 148 286 2.1E-114 T 11-10-2018 TO73_2092 4e101873393573796144b4963d83c044 310 SUPERFAMILY SSF53271 70 301 2.32E-57 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_0157 2d4723fb3f3883edf9e673959f069c11 549 SUPERFAMILY SSF52743 145 427 2.23E-64 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_0157 2d4723fb3f3883edf9e673959f069c11 549 Pfam PF00082 Subtilase family 160 416 1.8E-36 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TO73_0157 2d4723fb3f3883edf9e673959f069c11 549 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 216 226 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TO73_0157 2d4723fb3f3883edf9e673959f069c11 549 Gene3D G3DSA:2.60.40.10 473 532 7.3E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0157 2d4723fb3f3883edf9e673959f069c11 549 Gene3D G3DSA:3.40.50.200 131 426 3.2E-65 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_0157 2d4723fb3f3883edf9e673959f069c11 549 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 369 379 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TO73_0157 2d4723fb3f3883edf9e673959f069c11 549 PRINTS PR00723 Subtilisin serine protease family (S8) signature 368 384 6.6E-13 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_0157 2d4723fb3f3883edf9e673959f069c11 549 PRINTS PR00723 Subtilisin serine protease family (S8) signature 212 225 6.6E-13 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_0157 2d4723fb3f3883edf9e673959f069c11 549 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 179 6.6E-13 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_1560 12838aaefd44d1b307c9b32202635b50 517 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 268 346 1.8E-12 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_1560 12838aaefd44d1b307c9b32202635b50 517 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 15 90 9.3E-18 T 11-10-2018 IPR010094 Transposase (putative), N-terminal TO73_1003 b5fe1295cb807be7786c10ec3c39e6dd 517 Gene3D G3DSA:3.40.605.10 40 500 2.0E-188 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TO73_1003 b5fe1295cb807be7786c10ec3c39e6dd 517 Pfam PF00171 Aldehyde dehydrogenase family 35 501 7.3E-169 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TO73_1003 b5fe1295cb807be7786c10ec3c39e6dd 517 Gene3D G3DSA:3.40.309.10 274 474 2.0E-188 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TO73_1003 b5fe1295cb807be7786c10ec3c39e6dd 517 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 298 309 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TO73_1003 b5fe1295cb807be7786c10ec3c39e6dd 517 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 270 277 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TO73_1003 b5fe1295cb807be7786c10ec3c39e6dd 517 SUPERFAMILY SSF53720 28 505 2.49E-162 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TO73_1003 b5fe1295cb807be7786c10ec3c39e6dd 517 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 28 515 3.4E-247 T 11-10-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 TO73_1029 093188ddbdeb0786e99003ca0c29aaa0 136 Pfam PF07905 Purine catabolism regulatory protein-like family 44 103 2.5E-12 T 11-10-2018 IPR012914 Purine catabolism PurC-like domain TO73_0126 8d89243c27a9b7a8979f790e2eece70a 101 Pfam PF01250 Ribosomal protein S6 3 92 3.3E-23 T 11-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0126 8d89243c27a9b7a8979f790e2eece70a 101 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 18.829 T 11-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 TO73_0126 8d89243c27a9b7a8979f790e2eece70a 101 Gene3D G3DSA:3.30.70.60 55 98 2.4E-16 T 11-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TO73_0126 8d89243c27a9b7a8979f790e2eece70a 101 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 11-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 TO73_0126 8d89243c27a9b7a8979f790e2eece70a 101 SUPERFAMILY SSF54995 1 96 1.83E-25 T 11-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0126 8d89243c27a9b7a8979f790e2eece70a 101 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 4.4E-20 T 11-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0126 8d89243c27a9b7a8979f790e2eece70a 101 Gene3D G3DSA:3.30.70.60 1 54 1.2E-18 T 11-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TO73_0274 9e0de013785295b10f03a6e12a302793 259 SMART SM00934 14 248 1.1E-17 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_0274 9e0de013785295b10f03a6e12a302793 259 SUPERFAMILY SSF51366 12 252 5.65E-54 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TO73_0274 9e0de013785295b10f03a6e12a302793 259 Gene3D G3DSA:3.20.20.70 14 257 5.7E-67 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0274 9e0de013785295b10f03a6e12a302793 259 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 14 221 7.8E-21 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_0274 9e0de013785295b10f03a6e12a302793 259 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 84 97 - T 11-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_0274 9e0de013785295b10f03a6e12a302793 259 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 13 228 1.3E-57 T 11-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_2173 7a7a8daec848b87aa9aef076fe80f033 118 TIGRFAM TIGR00526 folB_dom: FolB domain 4 113 6.8E-20 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TO73_2173 7a7a8daec848b87aa9aef076fe80f033 118 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 113 4.8E-32 T 11-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TO73_2173 7a7a8daec848b87aa9aef076fe80f033 118 Pfam PF02152 Dihydroneopterin aldolase 4 112 3.5E-29 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TO73_2173 7a7a8daec848b87aa9aef076fe80f033 118 Gene3D G3DSA:3.30.1130.10 1 118 6.9E-35 T 11-10-2018 TO73_2173 7a7a8daec848b87aa9aef076fe80f033 118 SMART SM00905 4 115 4.1E-40 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TO73_2173 7a7a8daec848b87aa9aef076fe80f033 118 SUPERFAMILY SSF55620 1 116 4.4E-30 T 11-10-2018 TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 SUPERFAMILY SSF53335 279 900 5.55E-58 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 Pfam PF02384 N-6 DNA Methylase 440 564 1.2E-4 T 11-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 756 762 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 Pfam PF07669 Eco57I restriction-modification methylase 753 852 1.5E-4 T 11-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 Gene3D G3DSA:3.40.50.150 415 620 5.8E-24 T 11-10-2018 TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 Gene3D G3DSA:3.40.50.150 661 885 8.7E-18 T 11-10-2018 TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 454 470 2.1E-16 T 11-10-2018 TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 498 512 2.1E-16 T 11-10-2018 TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 753 765 2.1E-16 T 11-10-2018 TO73_2877 45ad83f503f5ca85771b30a1a9c596ae 1309 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 789 813 2.1E-16 T 11-10-2018 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SUPERFAMILY SSF55781 201 346 9.6E-15 T 11-10-2018 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SMART SM00065 471 605 0.03 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SMART SM00065 200 346 9.2E-4 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SMART SM00091 609 677 1.5E-8 T 11-10-2018 IPR000014 PAS domain TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 PRINTS PR00344 Bacterial sensor protein C-terminal signature 937 950 4.3E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 PRINTS PR00344 Bacterial sensor protein C-terminal signature 913 931 4.3E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 PRINTS PR00344 Bacterial sensor protein C-terminal signature 878 892 4.3E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 PRINTS PR00344 Bacterial sensor protein C-terminal signature 896 906 4.3E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SUPERFAMILY SSF55874 785 954 4.32E-51 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 Gene3D G3DSA:3.30.450.40 439 600 2.3E-9 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 842 951 1.6E-27 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 Gene3D G3DSA:1.10.287.130 723 796 2.1E-21 T 11-10-2018 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 Pfam PF00512 His Kinase A (phospho-acceptor) domain 732 796 4.1E-19 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 Gene3D G3DSA:3.30.450.20 602 722 8.7E-20 T 11-10-2018 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SUPERFAMILY SSF55785 594 721 4.51E-21 T 11-10-2018 IPR035965 PAS domain superfamily TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 Gene3D G3DSA:3.30.450.40 174 348 1.6E-18 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SMART SM00387 841 953 1.7E-44 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 Gene3D G3DSA:3.30.565.10 797 955 2.8E-46 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SUPERFAMILY SSF47384 719 797 1.12E-21 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 Pfam PF13185 GAF domain 200 335 3.1E-7 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 Pfam PF08447 PAS fold 633 704 6.2E-12 T 11-10-2018 IPR013655 PAS fold-3 GO:0005515 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SUPERFAMILY SSF55781 437 596 1.61E-8 T 11-10-2018 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 SMART SM00388 731 796 4.8E-22 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_1042 81f85c17ea33370b6ffc25dffdd8683b 958 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 606 730 1.8E-14 T 11-10-2018 IPR000014 PAS domain TO73_1682 09e753ebe21529f8afb733373f526239 250 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 20 250 2.0E-91 T 11-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TO73_1682 09e753ebe21529f8afb733373f526239 250 PIRSF PIRSF005650 15 250 5.8E-93 T 11-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TO73_1682 09e753ebe21529f8afb733373f526239 250 Hamap MF_01220_B Uridylate kinase [pyrH]. 18 250 44.241 T 11-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TO73_1682 09e753ebe21529f8afb733373f526239 250 Gene3D G3DSA:3.40.1160.10 13 250 3.3E-79 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_1682 09e753ebe21529f8afb733373f526239 250 Pfam PF00696 Amino acid kinase family 21 229 5.0E-28 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TO73_1682 09e753ebe21529f8afb733373f526239 250 SUPERFAMILY SSF53633 18 250 1.19E-72 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_0877 81f90eb7ee41ac411ac3084a5f0317e1 253 Gene3D G3DSA:3.40.50.10090 31 159 6.9E-75 T 11-10-2018 TO73_0877 81f90eb7ee41ac411ac3084a5f0317e1 253 Pfam PF02602 Uroporphyrinogen-III synthase HemD 13 242 3.4E-35 T 11-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_0877 81f90eb7ee41ac411ac3084a5f0317e1 253 SUPERFAMILY SSF69618 7 250 1.02E-46 T 11-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_0877 81f90eb7ee41ac411ac3084a5f0317e1 253 Gene3D G3DSA:3.40.50.10090 7 240 6.9E-75 T 11-10-2018 TO73_0332 949b2cde68abb5bb469f42cc9c0c368d 124 Pfam PF03061 Thioesterase superfamily 18 88 1.5E-17 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TO73_0332 949b2cde68abb5bb469f42cc9c0c368d 124 Gene3D G3DSA:3.10.129.10 1 122 1.2E-34 T 11-10-2018 TO73_0332 949b2cde68abb5bb469f42cc9c0c368d 124 SUPERFAMILY SSF54637 4 119 1.15E-34 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_1023 f62e065b2e5638e1fccc1d6d0d4b60f2 279 SUPERFAMILY SSF54675 6 109 6.28E-31 T 11-10-2018 TO73_1023 f62e065b2e5638e1fccc1d6d0d4b60f2 279 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 20 108 1.8E-25 T 11-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TO73_1023 f62e065b2e5638e1fccc1d6d0d4b60f2 279 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 11 274 1.0E-100 T 11-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 TO73_1023 f62e065b2e5638e1fccc1d6d0d4b60f2 279 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 110 274 1.9E-61 T 11-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TO73_1023 f62e065b2e5638e1fccc1d6d0d4b60f2 279 PIRSF PIRSF006250 3 278 8.2E-96 T 11-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 TO73_1023 f62e065b2e5638e1fccc1d6d0d4b60f2 279 Gene3D G3DSA:3.20.20.70 124 266 3.2E-112 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1023 f62e065b2e5638e1fccc1d6d0d4b60f2 279 Gene3D G3DSA:3.90.1170.20 14 274 3.2E-112 T 11-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TO73_1023 f62e065b2e5638e1fccc1d6d0d4b60f2 279 SUPERFAMILY SSF51690 110 274 5.1E-61 T 11-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TO73_2160 f32c1ec5a8b628ed9f36c21682d3b67c 93 Pfam PF02583 Metal-sensitive transcriptional repressor 13 90 9.3E-23 T 11-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 TO73_2160 f32c1ec5a8b628ed9f36c21682d3b67c 93 Gene3D G3DSA:1.20.58.1000 2 93 3.4E-24 T 11-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily TO73_0374 f2003d709b999b8508c6757c2a143488 406 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 406 61.531 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_0374 f2003d709b999b8508c6757c2a143488 406 SUPERFAMILY SSF50465 310 405 2.22E-36 T 11-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TO73_0374 f2003d709b999b8508c6757c2a143488 406 Pfam PF03143 Elongation factor Tu C-terminal domain 310 404 7.2E-35 T 11-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TO73_0374 f2003d709b999b8508c6757c2a143488 406 Gene3D G3DSA:2.40.30.10 217 346 5.1E-59 T 11-10-2018 TO73_0374 f2003d709b999b8508c6757c2a143488 406 Gene3D G3DSA:2.40.30.10 350 405 1.0E-29 T 11-10-2018 TO73_0374 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0374 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0374 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0374 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 132 141 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0374 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 59 67 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0374 f2003d709b999b8508c6757c2a143488 406 SUPERFAMILY SSF52540 6 230 4.8E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0374 f2003d709b999b8508c6757c2a143488 406 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 7.2E-16 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_0374 f2003d709b999b8508c6757c2a143488 406 Pfam PF03144 Elongation factor Tu domain 2 236 305 3.1E-18 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TO73_0374 f2003d709b999b8508c6757c2a143488 406 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 406 1.6E-223 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_0374 f2003d709b999b8508c6757c2a143488 406 Pfam PF00009 Elongation factor Tu GTP binding domain 10 212 4.0E-62 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0374 f2003d709b999b8508c6757c2a143488 406 SUPERFAMILY SSF50447 216 313 3.34E-32 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_0374 f2003d709b999b8508c6757c2a143488 406 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site TO73_0374 f2003d709b999b8508c6757c2a143488 406 Gene3D G3DSA:3.40.50.300 3 214 2.3E-72 T 11-10-2018 TO73_0080 f2003d709b999b8508c6757c2a143488 406 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 406 61.531 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_0080 f2003d709b999b8508c6757c2a143488 406 SUPERFAMILY SSF50465 310 405 2.22E-36 T 11-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TO73_0080 f2003d709b999b8508c6757c2a143488 406 Pfam PF03143 Elongation factor Tu C-terminal domain 310 404 7.2E-35 T 11-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TO73_0080 f2003d709b999b8508c6757c2a143488 406 Gene3D G3DSA:2.40.30.10 217 346 5.1E-59 T 11-10-2018 TO73_0080 f2003d709b999b8508c6757c2a143488 406 Gene3D G3DSA:2.40.30.10 350 405 1.0E-29 T 11-10-2018 TO73_0080 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0080 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0080 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0080 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 132 141 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0080 f2003d709b999b8508c6757c2a143488 406 PRINTS PR00315 GTP-binding elongation factor signature 59 67 6.4E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0080 f2003d709b999b8508c6757c2a143488 406 SUPERFAMILY SSF52540 6 230 4.8E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0080 f2003d709b999b8508c6757c2a143488 406 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 7.2E-16 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_0080 f2003d709b999b8508c6757c2a143488 406 Pfam PF03144 Elongation factor Tu domain 2 236 305 3.1E-18 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TO73_0080 f2003d709b999b8508c6757c2a143488 406 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 406 1.6E-223 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_0080 f2003d709b999b8508c6757c2a143488 406 Pfam PF00009 Elongation factor Tu GTP binding domain 10 212 4.0E-62 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0080 f2003d709b999b8508c6757c2a143488 406 SUPERFAMILY SSF50447 216 313 3.34E-32 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_0080 f2003d709b999b8508c6757c2a143488 406 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site TO73_0080 f2003d709b999b8508c6757c2a143488 406 Gene3D G3DSA:3.40.50.300 3 214 2.3E-72 T 11-10-2018 TO73_0376 6c392292b569ff98bcd322a5918e3487 206 Gene3D G3DSA:2.40.30.10 126 205 6.0E-17 T 11-10-2018 TO73_0376 6c392292b569ff98bcd322a5918e3487 206 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 199 3.4E-85 T 11-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0376 6c392292b569ff98bcd322a5918e3487 206 Pfam PF00297 Ribosomal protein L3 91 175 2.4E-14 T 11-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0376 6c392292b569ff98bcd322a5918e3487 206 Gene3D G3DSA:2.40.50.620 30 88 1.7E-17 T 11-10-2018 TO73_0376 6c392292b569ff98bcd322a5918e3487 206 SUPERFAMILY SSF50447 2 203 3.0E-76 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_0376 6c392292b569ff98bcd322a5918e3487 206 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 202 38.432 T 11-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0376 6c392292b569ff98bcd322a5918e3487 206 ProSitePatterns PS00474 Ribosomal protein L3 signature. 96 119 - T 11-10-2018 IPR019926 Ribosomal protein L3, conserved site TO73_1695 2d8e2d3936fed8411c910d4a662a2d02 182 Pfam PF02517 CAAX protease self-immunity 87 173 1.1E-19 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TO73_2379 838d93e063610a3d0527adddc1164df6 783 SMART SM00874 399 466 4.3E-25 T 11-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TO73_2379 838d93e063610a3d0527adddc1164df6 783 SUPERFAMILY SSF46955 1 178 3.11E-11 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily TO73_2379 838d93e063610a3d0527adddc1164df6 783 SUPERFAMILY SSF56037 194 396 9.15E-64 T 11-10-2018 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Pfam PF03484 tRNA synthetase B5 domain 403 466 7.1E-17 T 11-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Pfam PF01588 Putative tRNA binding domain 45 137 1.4E-6 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Gene3D G3DSA:3.30.70.380 692 783 8.4E-32 T 11-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TO73_2379 838d93e063610a3d0527adddc1164df6 783 SUPERFAMILY SSF54991 685 776 6.8E-27 T 11-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 777 39.727 T 11-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TO73_2379 838d93e063610a3d0527adddc1164df6 783 SMART SM00896 690 782 2.6E-37 T 11-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TO73_2379 838d93e063610a3d0527adddc1164df6 783 SUPERFAMILY SSF50249 42 146 1.17E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_2379 838d93e063610a3d0527adddc1164df6 783 SMART SM00873 207 383 5.5E-74 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Pfam PF03483 B3/4 domain 208 383 2.1E-57 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Gene3D G3DSA:3.30.930.10 486 680 5.2E-53 T 11-10-2018 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Gene3D G3DSA:2.40.50.140 38 151 6.4E-55 T 11-10-2018 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Gene3D G3DSA:3.50.40.10 186 398 5.2E-81 T 11-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 TO73_2379 838d93e063610a3d0527adddc1164df6 783 SUPERFAMILY SSF55681 462 677 4.12E-43 T 11-10-2018 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Gene3D G3DSA:3.30.56.10 399 471 2.3E-25 T 11-10-2018 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Pfam PF03147 Ferredoxin-fold anticodon binding domain 690 777 2.2E-26 T 11-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TO73_2379 838d93e063610a3d0527adddc1164df6 783 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 775 6.4E-186 T 11-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TO73_2379 838d93e063610a3d0527adddc1164df6 783 Gene3D G3DSA:3.30.56.10 1 177 6.4E-55 T 11-10-2018 TO73_2379 838d93e063610a3d0527adddc1164df6 783 SUPERFAMILY SSF46955 400 470 1.01E-15 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily TO73_1562 d5893fbd66d0dc199fd152f9fc2b52b8 313 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 137 1.8E-12 T 11-10-2018 IPR016188 PurM-like, N-terminal domain TO73_1562 d5893fbd66d0dc199fd152f9fc2b52b8 313 Gene3D G3DSA:3.90.650.10 145 311 3.4E-43 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TO73_1562 d5893fbd66d0dc199fd152f9fc2b52b8 313 Gene3D G3DSA:3.30.1330.10 1 142 2.1E-29 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TO73_1562 d5893fbd66d0dc199fd152f9fc2b52b8 313 SUPERFAMILY SSF56042 146 311 1.03E-20 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TO73_1562 d5893fbd66d0dc199fd152f9fc2b52b8 313 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 6 311 20.359 T 11-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TO73_1562 d5893fbd66d0dc199fd152f9fc2b52b8 313 SUPERFAMILY SSF55326 4 137 2.09E-22 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TO73_1562 d5893fbd66d0dc199fd152f9fc2b52b8 313 Pfam PF02769 AIR synthase related protein, C-terminal domain 149 299 2.1E-7 T 11-10-2018 IPR010918 PurM-like, C-terminal domain TO73_1562 d5893fbd66d0dc199fd152f9fc2b52b8 313 PIRSF PIRSF005303 1 311 9.2E-59 T 11-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TO73_2836 57f779f1f7f6fc5701e2a8417668df40 955 SMART SM00248 735 764 2.1E-4 T 11-10-2018 IPR002110 Ankyrin repeat GO:0005515 TO73_2836 57f779f1f7f6fc5701e2a8417668df40 955 Gene3D G3DSA:1.25.40.20 639 799 1.7E-11 T 11-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TO73_2836 57f779f1f7f6fc5701e2a8417668df40 955 SUPERFAMILY SSF48403 727 778 2.8E-11 T 11-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TO73_2836 57f779f1f7f6fc5701e2a8417668df40 955 Gene3D G3DSA:3.40.50.300 397 582 2.0E-6 T 11-10-2018 TO73_2836 57f779f1f7f6fc5701e2a8417668df40 955 Gene3D G3DSA:3.40.50.300 155 382 4.9E-8 T 11-10-2018 TO73_2836 57f779f1f7f6fc5701e2a8417668df40 955 SUPERFAMILY SSF52540 159 564 1.75E-29 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2836 57f779f1f7f6fc5701e2a8417668df40 955 Pfam PF13857 Ankyrin repeats (many copies) 735 776 1.1E-6 T 11-10-2018 TO73_0354 77295a56aa042986bd126efe9ea8d4c2 224 SMART SM00862 145 221 1.6E-28 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_0354 77295a56aa042986bd126efe9ea8d4c2 224 SUPERFAMILY SSF52172 1 173 8.2E-41 T 11-10-2018 IPR011006 CheY-like superfamily TO73_0354 77295a56aa042986bd126efe9ea8d4c2 224 SMART SM00448 2 114 4.9E-40 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_0354 77295a56aa042986bd126efe9ea8d4c2 224 Gene3D G3DSA:1.10.10.10 123 224 4.3E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0354 77295a56aa042986bd126efe9ea8d4c2 224 Gene3D G3DSA:3.40.50.2300 1 122 1.9E-36 T 11-10-2018 TO73_0354 77295a56aa042986bd126efe9ea8d4c2 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 221 3.5E-27 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_0354 77295a56aa042986bd126efe9ea8d4c2 224 Pfam PF00072 Response regulator receiver domain 4 115 9.3E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1704 efd9a3d5cbf198376de4a868a4c724ac 219 SMART SM00450 116 216 6.1E-26 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1704 efd9a3d5cbf198376de4a868a4c724ac 219 SMART SM00450 8 103 8.3E-27 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1704 efd9a3d5cbf198376de4a868a4c724ac 219 Pfam PF00581 Rhodanese-like domain 124 212 2.1E-16 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1704 efd9a3d5cbf198376de4a868a4c724ac 219 Pfam PF00581 Rhodanese-like domain 14 99 8.0E-17 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1704 efd9a3d5cbf198376de4a868a4c724ac 219 Gene3D G3DSA:3.40.250.10 124 219 1.4E-31 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1704 efd9a3d5cbf198376de4a868a4c724ac 219 Gene3D G3DSA:3.40.250.10 12 116 6.5E-31 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1704 efd9a3d5cbf198376de4a868a4c724ac 219 SUPERFAMILY SSF52821 4 106 1.3E-34 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1704 efd9a3d5cbf198376de4a868a4c724ac 219 ProSitePatterns PS00380 Rhodanese signature 1. 144 155 - T 11-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TO73_1704 efd9a3d5cbf198376de4a868a4c724ac 219 SUPERFAMILY SSF52821 113 219 1.3E-35 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1956 aa027776d7f4fa355c71d19e38141852 444 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 6 441 2.6E-171 T 11-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 TO73_1956 aa027776d7f4fa355c71d19e38141852 444 SUPERFAMILY SSF52540 180 432 1.09E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1956 aa027776d7f4fa355c71d19e38141852 444 Gene3D G3DSA:3.40.50.300 164 444 1.1E-109 T 11-10-2018 TO73_1956 aa027776d7f4fa355c71d19e38141852 444 Gene3D G3DSA:1.10.860.10 1 149 1.3E-61 T 11-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal TO73_1956 aa027776d7f4fa355c71d19e38141852 444 Pfam PF00772 DnaB-like helicase N terminal domain 6 108 2.3E-35 T 11-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 TO73_1956 aa027776d7f4fa355c71d19e38141852 444 Pfam PF03796 DnaB-like helicase C terminal domain 182 439 6.6E-110 T 11-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 TO73_1956 aa027776d7f4fa355c71d19e38141852 444 SUPERFAMILY SSF48024 5 116 1.2E-35 T 11-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 SMART SM00028 134 167 37.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 SMART SM00028 284 317 44.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 SMART SM00028 248 281 48.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 SMART SM00028 210 243 1.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 SMART SM00028 320 353 0.44 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 Pfam PF13432 Tetratricopeptide repeat 291 346 2.4E-4 T 11-10-2018 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 SUPERFAMILY SSF48452 140 349 3.57E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 Gene3D G3DSA:1.25.40.10 209 448 2.0E-22 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 212 273 7.2E-7 T 11-10-2018 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 Pfam PF12862 Anaphase-promoting complex subunit 5 5 63 0.43 T 11-10-2018 IPR026000 Anaphase-promoting complex subunit 5 domain Reactome: R-HSA-141430|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-176407|Reactome: R-HSA-176408|Reactome: R-HSA-176409|Reactome: R-HSA-176412|Reactome: R-HSA-179409|Reactome: R-HSA-2467813|Reactome: R-HSA-2559582|Reactome: R-HSA-69017|Reactome: R-HSA-983168 TO73_1794 c4bcff489ed2326ec8e8baff285cd88e 451 SUPERFAMILY SSF48452 99 171 6.3E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0870 0eb63ef94c028053825439ae0a75e3b4 199 Gene3D G3DSA:1.10.490.10 29 170 5.6E-23 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TO73_0870 0eb63ef94c028053825439ae0a75e3b4 199 SUPERFAMILY SSF46458 30 158 1.76E-15 T 11-10-2018 IPR009050 Globin-like superfamily TO73_0870 0eb63ef94c028053825439ae0a75e3b4 199 Pfam PF11563 Protoglobin 30 167 3.7E-17 T 11-10-2018 TO73_0015 1bf9a45949492907eb0d1e01287664fc 68 PIRSF PIRSF002599 1 68 1.8E-23 T 11-10-2018 IPR012156 Cold shock, CspA GO:0003676 TO73_0015 1bf9a45949492907eb0d1e01287664fc 68 Gene3D G3DSA:2.40.50.140 1 68 3.8E-32 T 11-10-2018 TO73_0015 1bf9a45949492907eb0d1e01287664fc 68 PRINTS PR00050 Cold shock protein signature 39 57 2.1E-17 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TO73_0015 1bf9a45949492907eb0d1e01287664fc 68 PRINTS PR00050 Cold shock protein signature 24 33 2.1E-17 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TO73_0015 1bf9a45949492907eb0d1e01287664fc 68 PRINTS PR00050 Cold shock protein signature 4 19 2.1E-17 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TO73_0015 1bf9a45949492907eb0d1e01287664fc 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 11-10-2018 IPR019844 Cold-shock conserved site TO73_0015 1bf9a45949492907eb0d1e01287664fc 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 67 3.6E-28 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TO73_0015 1bf9a45949492907eb0d1e01287664fc 68 SUPERFAMILY SSF50249 1 67 4.93E-22 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0015 1bf9a45949492907eb0d1e01287664fc 68 SMART SM00357 3 68 4.7E-29 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 TO73_2005 caef5d7a2d8289463e042dbeaa9aeb52 134 Pfam PF06271 RDD family 3 124 1.6E-29 T 11-10-2018 IPR010432 RDD TO73_0975 de43a08dfc9b658fd47f7e783770fc66 80 Gene3D G3DSA:3.40.50.1010 1 76 1.2E-13 T 11-10-2018 TO73_0975 de43a08dfc9b658fd47f7e783770fc66 80 SUPERFAMILY SSF88723 2 75 8.97E-12 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_1459 cbd809da00d8283fc686fa4f9b6542aa 298 Gene3D G3DSA:3.60.15.10 2 253 3.4E-56 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_1459 cbd809da00d8283fc686fa4f9b6542aa 298 SMART SM00849 14 208 1.2E-32 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_1459 cbd809da00d8283fc686fa4f9b6542aa 298 SUPERFAMILY SSF56281 15 251 8.39E-50 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_1459 cbd809da00d8283fc686fa4f9b6542aa 298 Pfam PF00753 Metallo-beta-lactamase superfamily 14 208 1.9E-21 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 SUPERFAMILY SSF88697 5 195 4.22E-39 T 11-10-2018 IPR015947 PUA-like superfamily TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 TIGRFAM TIGR00763 lon: endopeptidase La 8 777 1.6E-287 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 358 496 4.7E-23 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 SUPERFAMILY SSF54211 601 776 8.72E-56 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 Gene3D G3DSA:2.30.130.40 1 112 4.0E-29 T 11-10-2018 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 Gene3D G3DSA:3.30.230.10 599 789 9.5E-80 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 SMART SM00464 5 197 8.8E-65 T 11-10-2018 IPR003111 Lon, substrate-binding domain TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 PIRSF PIRSF001174 2 780 0.0 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 576 778 6.4E-92 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 5 195 1.5E-37 T 11-10-2018 IPR003111 Lon, substrate-binding domain TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 SMART SM00382 354 502 3.6E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 Gene3D G3DSA:1.20.58.1480 118 240 2.5E-38 T 11-10-2018 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 Gene3D G3DSA:1.10.8.60 498 590 2.6E-32 T 11-10-2018 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 Gene3D G3DSA:3.40.50.300 307 497 3.0E-66 T 11-10-2018 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 732 750 4.1E-49 T 11-10-2018 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 601 617 4.1E-49 T 11-10-2018 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 362 381 4.1E-49 T 11-10-2018 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 679 698 4.1E-49 T 11-10-2018 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 709 728 4.1E-49 T 11-10-2018 TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 SUPERFAMILY SSF52540 304 590 3.56E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0762 1382d668f3a36a44b7ac38399b03c6f3 804 Hamap MF_01973 Lon protease [lon]. 6 778 70.75 T 11-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 TO73_0978 44f07cc155d3596026ca703536603dc8 86 Pfam PF09827 CRISPR associated protein Cas2 2 68 1.1E-15 T 11-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 TO73_0978 44f07cc155d3596026ca703536603dc8 86 SUPERFAMILY SSF143430 2 80 1.44E-20 T 11-10-2018 TO73_0978 44f07cc155d3596026ca703536603dc8 86 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 2 81 9.3E-9 T 11-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TO73_0978 44f07cc155d3596026ca703536603dc8 86 Gene3D G3DSA:3.30.70.240 1 64 6.2E-24 T 11-10-2018 TO73_0978 44f07cc155d3596026ca703536603dc8 86 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 86 14.342 T 11-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 138 3.0E-27 T 11-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 SUPERFAMILY SSF54747 2 71 1.96E-28 T 11-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 4 140 30.779 T 11-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 ProSitePatterns PS00359 Ribosomal protein L11 signature. 125 140 - T 11-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 SMART SM00649 8 139 7.8E-86 T 11-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 Gene3D G3DSA:1.10.10.2720 72 147 9.3E-34 T 11-10-2018 TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 2 139 1.6E-62 T 11-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 Gene3D G3DSA:3.30.1550.10 1 71 2.1E-34 T 11-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 SUPERFAMILY SSF46906 66 139 5.49E-28 T 11-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 Pfam PF03946 Ribosomal protein L11, N-terminal domain 8 65 2.5E-27 T 11-10-2018 IPR020784 Ribosomal protein L11, N-terminal TO73_0084 c590a8ca69e8c44bcbf6159c75159625 147 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 35 72 4.0E-15 T 11-10-2018 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 Pfam PF00990 Diguanylate cyclase, GGDEF domain 592 742 3.3E-39 T 11-10-2018 IPR000160 GGDEF domain TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 SMART SM00267 581 746 1.2E-47 T 11-10-2018 IPR000160 GGDEF domain TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 SUPERFAMILY SSF55781 429 592 2.09E-12 T 11-10-2018 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 SUPERFAMILY SSF55073 597 742 1.54E-43 T 11-10-2018 IPR029787 Nucleotide cyclase TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 Gene3D G3DSA:3.30.450.40 414 589 9.6E-18 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 Gene3D G3DSA:3.30.450.40 247 413 5.1E-15 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 SUPERFAMILY SSF55781 86 245 3.93E-22 T 11-10-2018 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 Gene3D G3DSA:3.30.450.40 90 246 6.2E-18 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 SMART SM00065 428 589 7.3E-4 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 SMART SM00065 267 415 0.13 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 SMART SM00065 50 253 5.3E-8 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 588 742 3.2E-41 T 11-10-2018 IPR000160 GGDEF domain TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 Pfam PF13185 GAF domain 427 579 3.2E-8 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 Pfam PF13185 GAF domain 266 406 3.5E-7 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 Pfam PF13185 GAF domain 159 243 5.5E-11 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 Gene3D G3DSA:3.30.70.270 590 747 4.1E-50 T 11-10-2018 TO73_1711 33628962771ebb83b3780e38f1e2aa34 747 SUPERFAMILY SSF55781 251 408 3.71E-9 T 11-10-2018 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 ProSitePatterns PS00447 DNA polymerase family A signature. 659 678 - T 11-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 14 171 1.4E-47 T 11-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 SMART SM00279 176 211 2.3E-13 T 11-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Gene3D G3DSA:3.30.420.10 293 446 1.5E-72 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 TIGRFAM TIGR00593 pola: DNA polymerase I 391 831 7.3E-207 T 11-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 SMART SM00278 216 235 1500.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 SMART SM00278 191 210 0.0065 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 SUPERFAMILY SSF56672 424 831 7.12E-157 T 11-10-2018 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 175 261 1.8E-27 T 11-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Gene3D G3DSA:3.30.70.370 567 827 1.1E-121 T 11-10-2018 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Pfam PF09281 Taq polymerase, exonuclease 295 420 3.2E-42 T 11-10-2018 IPR015361 Taq polymerase, thermostable, exonuclease region GO:0001882|GO:0003887|GO:0006260|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 SMART SM00482 591 795 1.6E-126 T 11-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Gene3D G3DSA:1.20.1060.10 447 563 3.7E-46 T 11-10-2018 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Gene3D G3DSA:1.10.150.20 177 249 1.8E-103 T 11-10-2018 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 SUPERFAMILY SSF53098 296 421 1.24E-30 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 SUPERFAMILY SSF47807 174 286 5.23E-34 T 11-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 SUPERFAMILY SSF88723 4 173 2.13E-52 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 SMART SM00475 12 264 5.3E-147 T 11-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 PRINTS PR00868 DNA-polymerase family A (pol I) signature 605 628 3.5E-85 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 PRINTS PR00868 DNA-polymerase family A (pol I) signature 635 648 3.5E-85 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 684 3.5E-85 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 PRINTS PR00868 DNA-polymerase family A (pol I) signature 560 582 3.5E-85 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 PRINTS PR00868 DNA-polymerase family A (pol I) signature 696 707 3.5E-85 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 PRINTS PR00868 DNA-polymerase family A (pol I) signature 718 729 3.5E-85 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 PRINTS PR00868 DNA-polymerase family A (pol I) signature 583 598 3.5E-85 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 PRINTS PR00868 DNA-polymerase family A (pol I) signature 778 791 3.5E-85 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 PRINTS PR00868 DNA-polymerase family A (pol I) signature 750 766 3.5E-85 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Gene3D G3DSA:3.40.50.1010 14 278 1.8E-103 T 11-10-2018 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Gene3D G3DSA:1.10.150.20 614 757 1.1E-121 T 11-10-2018 TO73_0712 73da06422bc5812f68488bf2d5f863e3 832 Pfam PF00476 DNA polymerase family A 455 828 1.1E-150 T 11-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 6 319 9.5E-130 T 11-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 118 147 - T 11-10-2018 IPR018239 NAD-dependent DNA ligase, active site TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Gene3D G3DSA:2.40.50.140 320 406 1.6E-31 T 11-10-2018 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Gene3D G3DSA:3.30.470.90 74 319 6.5E-91 T 11-10-2018 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SUPERFAMILY SSF52113 586 665 1.45E-21 T 11-10-2018 IPR036420 BRCT domain superfamily TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Gene3D G3DSA:1.10.287.610 1 73 1.6E-33 T 11-10-2018 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 591 661 1.7E-13 T 11-10-2018 IPR001357 BRCT domain TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Gene3D G3DSA:3.40.50.10190 585 673 2.2E-28 T 11-10-2018 IPR036420 BRCT domain superfamily TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Pfam PF12826 Helix-hairpin-helix motif 508 571 5.3E-18 T 11-10-2018 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SUPERFAMILY SSF56091 2 317 1.12E-115 T 11-10-2018 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SMART SM00278 542 561 0.016 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SMART SM00278 510 529 100.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SMART SM00278 444 463 1.2 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SMART SM00278 478 497 3.5 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 322 399 3.5E-32 T 11-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 PIRSF PIRSF001604 1 665 3.0E-240 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Gene3D G3DSA:1.10.150.20 430 502 1.2E-31 T 11-10-2018 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Pfam PF14520 Helix-hairpin-helix domain 444 498 1.7E-8 T 11-10-2018 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 332 347 - T 11-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SMART SM00532 5 446 3.8E-286 T 11-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SMART SM00292 588 664 2.3E-16 T 11-10-2018 IPR001357 BRCT domain TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SUPERFAMILY SSF47781 405 581 3.26E-62 T 11-10-2018 IPR010994 RuvA domain 2-like TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Gene3D G3DSA:1.10.150.20 503 584 3.3E-27 T 11-10-2018 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 SUPERFAMILY SSF50249 318 401 7.2E-27 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 Hamap MF_01588 DNA ligase [ligA]. 4 661 50.447 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TO73_1739 ad28cf8b51d675c35a51aa56c9f5bb28 674 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 657 8.7E-258 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TO73_0615 4c2b6e5b9f6571d691df65e07d59e866 714 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 175 618 9.7E-52 T 11-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TO73_0615 4c2b6e5b9f6571d691df65e07d59e866 714 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 134 705 4.1E-113 T 11-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TO73_0239 1f688d5bde5926bb798b74958df6045a 353 SUPERFAMILY SSF53383 2 350 2.69E-88 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_0239 1f688d5bde5926bb798b74958df6045a 353 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 177 197 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TO73_0239 1f688d5bde5926bb798b74958df6045a 353 Gene3D G3DSA:3.40.640.10 12 252 1.0E-126 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_0239 1f688d5bde5926bb798b74958df6045a 353 PIRSF PIRSF000524 1 353 1.8E-97 T 11-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TO73_0239 1f688d5bde5926bb798b74958df6045a 353 Gene3D G3DSA:3.90.1150.10 3 334 1.0E-126 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_0239 1f688d5bde5926bb798b74958df6045a 353 Pfam PF00266 Aminotransferase class-V 52 316 2.5E-29 T 11-10-2018 IPR000192 Aminotransferase class V domain TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 PIRSF PIRSF003101 1 398 4.2E-120 T 11-10-2018 IPR020823 Cell division protein FtsA TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 Gene3D G3DSA:3.30.1490.110 65 148 7.8E-95 T 11-10-2018 TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 Gene3D G3DSA:3.30.420.40 176 331 7.8E-95 T 11-10-2018 TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 SUPERFAMILY SSF53067 7 176 1.25E-44 T 11-10-2018 TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 Pfam PF14450 Cell division protein FtsA 187 353 1.6E-23 T 11-10-2018 TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 SUPERFAMILY SSF53067 178 356 2.2E-39 T 11-10-2018 TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 1 357 3.9E-105 T 11-10-2018 IPR020823 Cell division protein FtsA TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 Pfam PF02491 SHS2 domain inserted in FTSA 63 140 2.4E-25 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 Gene3D G3DSA:3.30.420.40 8 351 7.8E-95 T 11-10-2018 TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 Hamap MF_02033 Cell division protein FtsA [ftsA]. 1 398 25.413 T 11-10-2018 IPR020823 Cell division protein FtsA TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 Gene3D G3DSA:3.90.640.10 214 278 7.8E-95 T 11-10-2018 TO73_1233 521f4239a38e7df2f6c151cb1245d377 398 SMART SM00842 1 175 4.1E-72 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 TO73_0372 7e9ac964f19ef3bac92a8142f94db952 155 PIRSF PIRSF002122 2 155 5.5E-62 T 11-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 TO73_0372 7e9ac964f19ef3bac92a8142f94db952 155 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 155 33.813 T 11-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TO73_0372 7e9ac964f19ef3bac92a8142f94db952 155 Pfam PF00177 Ribosomal protein S7p/S5e 2 148 2.0E-62 T 11-10-2018 IPR023798 Ribosomal protein S7 domain TO73_0372 7e9ac964f19ef3bac92a8142f94db952 155 SUPERFAMILY SSF47973 5 148 4.58E-59 T 11-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TO73_0372 7e9ac964f19ef3bac92a8142f94db952 155 Gene3D G3DSA:1.10.455.10 5 155 4.2E-65 T 11-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TO73_0372 7e9ac964f19ef3bac92a8142f94db952 155 ProSitePatterns PS00052 Ribosomal protein S7 signature. 19 45 - T 11-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0372 7e9ac964f19ef3bac92a8142f94db952 155 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 2 155 9.3E-64 T 11-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 205 470 21.792 T 11-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 3 191 22.373 T 11-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 Gene3D G3DSA:3.40.1190.20 200 467 1.2E-73 T 11-10-2018 IPR029056 Ribokinase-like TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 406 416 - T 11-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 SUPERFAMILY SSF64153 2 227 1.44E-55 T 11-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 Gene3D G3DSA:3.40.50.10260 1 197 1.1E-50 T 11-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 2 192 4.0E-35 T 11-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 Pfam PF01256 Carbohydrate kinase 239 463 3.5E-45 T 11-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 208 464 2.3E-52 T 11-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 Pfam PF03853 YjeF-related protein N-terminus 24 171 8.7E-33 T 11-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 PIRSF PIRSF017184 1 472 2.9E-104 T 11-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 TO73_0541 2f8030e6536d33888d8d8d20fea7aeae 480 SUPERFAMILY SSF53613 205 465 1.01E-62 T 11-10-2018 IPR029056 Ribokinase-like TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 Gene3D G3DSA:1.25.40.10 220 357 1.5E-23 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 Pfam PF13181 Tetratricopeptide repeat 144 174 2.2E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 Pfam PF14559 Tetratricopeptide repeat 41 87 1.1E-10 T 11-10-2018 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 Pfam PF14559 Tetratricopeptide repeat 256 320 2.3E-6 T 11-10-2018 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 Pfam PF14559 Tetratricopeptide repeat 188 246 5.2E-9 T 11-10-2018 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 SUPERFAMILY SSF48452 37 169 4.63E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 SUPERFAMILY SSF48452 127 350 1.77E-34 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 SMART SM00028 178 210 0.39 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 SMART SM00028 314 347 17.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 SMART SM00028 280 313 15.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 SMART SM00028 38 64 94.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 SMART SM00028 144 177 7.2E-5 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 SMART SM00028 245 278 0.29 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 SMART SM00028 65 98 260.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0796 d2d2532a15025a630a0e4bc19f32ad20 357 Gene3D G3DSA:1.25.40.10 28 219 3.2E-57 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0634 6b0c78c252db4b94ae1af042a028711c 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 62 77 - T 11-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0634 6b0c78c252db4b94ae1af042a028711c 235 Gene3D G3DSA:3.40.50.1580 1 235 2.3E-80 T 11-10-2018 TO73_0634 6b0c78c252db4b94ae1af042a028711c 235 SUPERFAMILY SSF53167 4 233 1.96E-78 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TO73_0634 6b0c78c252db4b94ae1af042a028711c 235 Pfam PF01048 Phosphorylase superfamily 16 231 9.0E-46 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TO73_0858 1f3c4e1241c400313de060deaa22593c 639 Gene3D G3DSA:3.40.50.300 478 635 4.1E-48 T 11-10-2018 TO73_0858 1f3c4e1241c400313de060deaa22593c 639 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 457 111.691 T 11-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TO73_0858 1f3c4e1241c400313de060deaa22593c 639 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 247 393 1.2E-23 T 11-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TO73_0858 1f3c4e1241c400313de060deaa22593c 639 Gene3D G3DSA:3.40.50.880 247 397 6.5E-15 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0858 1f3c4e1241c400313de060deaa22593c 639 SUPERFAMILY SSF52540 478 635 6.02E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0858 1f3c4e1241c400313de060deaa22593c 639 Gene3D G3DSA:3.40.50.300 4 231 8.3E-44 T 11-10-2018 TO73_0858 1f3c4e1241c400313de060deaa22593c 639 Pfam PF13500 AAA domain 6 228 2.7E-15 T 11-10-2018 TO73_0858 1f3c4e1241c400313de060deaa22593c 639 SUPERFAMILY SSF52540 5 236 1.21E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0858 1f3c4e1241c400313de060deaa22593c 639 SUPERFAMILY SSF52317 191 402 1.35E-25 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0858 1f3c4e1241c400313de060deaa22593c 639 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 478 635 2.3E-52 T 11-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 TO73_1647 68c0c2f7d7f937305472c93df5c789e2 413 Pfam PF06965 Na+/H+ antiporter 1 9 400 6.5E-139 T 11-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TO73_1647 68c0c2f7d7f937305472c93df5c789e2 413 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 7 409 22.43 T 11-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TO73_1647 68c0c2f7d7f937305472c93df5c789e2 413 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 11 400 9.3E-124 T 11-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TO73_1647 68c0c2f7d7f937305472c93df5c789e2 413 PRINTS PR00173 Glutamate-aspartate symporter signature 298 320 2.7E-6 T 11-10-2018 TO73_1647 68c0c2f7d7f937305472c93df5c789e2 413 PRINTS PR00173 Glutamate-aspartate symporter signature 134 154 2.7E-6 T 11-10-2018 TO73_1647 68c0c2f7d7f937305472c93df5c789e2 413 PRINTS PR00173 Glutamate-aspartate symporter signature 212 237 2.7E-6 T 11-10-2018 TO73_1647 68c0c2f7d7f937305472c93df5c789e2 413 Gene3D G3DSA:1.20.1530.10 4 408 2.0E-137 T 11-10-2018 IPR023171 Na/H antiporter domain superfamily TO73_2195 4a419730ca1e5228209759cf5a0608cc 434 SUPERFAMILY SSF81296 19 93 7.17E-7 T 11-10-2018 IPR014756 Immunoglobulin E-set TO73_2195 4a419730ca1e5228209759cf5a0608cc 434 Pfam PF00082 Subtilase family 191 421 2.8E-29 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TO73_2195 4a419730ca1e5228209759cf5a0608cc 434 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 378 388 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TO73_2195 4a419730ca1e5228209759cf5a0608cc 434 PRINTS PR00723 Subtilisin serine protease family (S8) signature 191 210 7.9E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_2195 4a419730ca1e5228209759cf5a0608cc 434 PRINTS PR00723 Subtilisin serine protease family (S8) signature 226 239 7.9E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_2195 4a419730ca1e5228209759cf5a0608cc 434 PRINTS PR00723 Subtilisin serine protease family (S8) signature 377 393 7.9E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_2195 4a419730ca1e5228209759cf5a0608cc 434 Gene3D G3DSA:3.40.50.200 171 433 7.1E-71 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_2195 4a419730ca1e5228209759cf5a0608cc 434 Gene3D G3DSA:2.60.40.10 20 95 9.9E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_2195 4a419730ca1e5228209759cf5a0608cc 434 SUPERFAMILY SSF52743 173 431 1.57E-69 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 PRINTS PR00691 Adhesin B signature 123 142 3.6E-15 T 11-10-2018 IPR006129 Adhesin B GO:0007155 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 PRINTS PR00691 Adhesin B signature 266 284 3.6E-15 T 11-10-2018 IPR006129 Adhesin B GO:0007155 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 PRINTS PR00691 Adhesin B signature 43 61 3.6E-15 T 11-10-2018 IPR006129 Adhesin B GO:0007155 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 PRINTS PR00691 Adhesin B signature 18 39 3.6E-15 T 11-10-2018 IPR006129 Adhesin B GO:0007155 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 PRINTS PR00691 Adhesin B signature 62 81 3.6E-15 T 11-10-2018 IPR006129 Adhesin B GO:0007155 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 SUPERFAMILY SSF53807 19 288 3.68E-57 T 11-10-2018 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 Pfam PF01297 Zinc-uptake complex component A periplasmic 21 285 1.4E-50 T 11-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 PRINTS PR00690 Adhesin family signature 18 36 1.1E-8 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 PRINTS PR00690 Adhesin family signature 178 199 1.1E-8 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 PRINTS PR00690 Adhesin family signature 49 62 1.1E-8 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 PRINTS PR00690 Adhesin family signature 62 79 1.1E-8 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 Gene3D G3DSA:3.40.50.1980 182 288 4.2E-14 T 11-10-2018 TO73_2243 4746b7af8b329b5c93f41c052caa69ed 290 Gene3D G3DSA:3.40.50.1980 18 180 1.0E-33 T 11-10-2018 TO73_0690 7da3a04b6756628402aec91e19bcbeab 141 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 1 129 14.327 T 11-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 TO73_0690 7da3a04b6756628402aec91e19bcbeab 141 SUPERFAMILY SSF74942 77 120 3.14E-5 T 11-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily TO73_0690 7da3a04b6756628402aec91e19bcbeab 141 Pfam PF17384 RimP C-terminal SH3 domain 79 120 2.3E-7 T 11-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal TO73_0690 7da3a04b6756628402aec91e19bcbeab 141 SUPERFAMILY SSF75420 3 74 1.96E-12 T 11-10-2018 IPR035956 RimP, N-terminal domain superfamily TO73_0690 7da3a04b6756628402aec91e19bcbeab 141 Gene3D G3DSA:3.30.300.70 2 73 1.7E-8 T 11-10-2018 IPR035956 RimP, N-terminal domain superfamily TO73_0690 7da3a04b6756628402aec91e19bcbeab 141 Pfam PF02576 RimP N-terminal domain 6 74 2.7E-13 T 11-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal TO73_0841 6513c2b426ac7d9c92cbf7b624770170 432 Gene3D G3DSA:3.90.1150.10 13 427 9.6E-153 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_0841 6513c2b426ac7d9c92cbf7b624770170 432 SUPERFAMILY SSF53383 28 430 9.68E-129 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_0841 6513c2b426ac7d9c92cbf7b624770170 432 Gene3D G3DSA:3.40.640.10 69 331 9.6E-153 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_0841 6513c2b426ac7d9c92cbf7b624770170 432 PIRSF PIRSF000521 129 432 1.7E-44 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0841 6513c2b426ac7d9c92cbf7b624770170 432 PIRSF PIRSF000521 1 136 4.6E-10 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0841 6513c2b426ac7d9c92cbf7b624770170 432 Pfam PF00202 Aminotransferase class-III 32 429 9.4E-116 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0841 6513c2b426ac7d9c92cbf7b624770170 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 Gene3D G3DSA:2.160.10.10 249 436 5.5E-53 T 11-10-2018 TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 449 1.5E-167 T 11-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 SUPERFAMILY SSF51161 251 434 1.67E-46 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 Gene3D G3DSA:3.90.550.10 3 247 6.6E-71 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 391 425 5.5E-8 T 11-10-2018 IPR001451 Hexapeptide repeat TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 Pfam PF12804 MobA-like NTP transferase domain 5 128 4.1E-21 T 11-10-2018 IPR025877 MobA-like NTP transferase TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 448 39.411 T 11-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 294 0.0011 T 11-10-2018 IPR001451 Hexapeptide repeat TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 399 427 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TO73_2056 cc803d5df4e19369ee5eed0287639a2d 453 SUPERFAMILY SSF53448 5 248 5.41E-60 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1353 ae6a2e85a7594365b1438341186831f2 157 Gene3D G3DSA:3.30.110.10 61 155 2.0E-36 T 11-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TO73_1353 ae6a2e85a7594365b1438341186831f2 157 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 68 152 1.1E-36 T 11-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 TO73_1353 ae6a2e85a7594365b1438341186831f2 157 SUPERFAMILY SSF54364 1 63 2.88E-23 T 11-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TO73_1353 ae6a2e85a7594365b1438341186831f2 157 Gene3D G3DSA:3.10.20.80 1 60 4.1E-26 T 11-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TO73_1353 ae6a2e85a7594365b1438341186831f2 157 SUPERFAMILY SSF55200 69 154 1.44E-31 T 11-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TO73_1353 ae6a2e85a7594365b1438341186831f2 157 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 154 6.8E-55 T 11-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TO73_1353 ae6a2e85a7594365b1438341186831f2 157 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 61 3.9E-25 T 11-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TO73_1353 ae6a2e85a7594365b1438341186831f2 157 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 24.826 T 11-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 Gene3D G3DSA:3.90.1170.30 324 408 1.6E-140 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 SMART SM00941 337 410 2.1E-24 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 SUPERFAMILY SSF52418 76 321 2.49E-80 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 Gene3D G3DSA:1.20.970.10 1 67 9.8E-23 T 11-10-2018 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 SUPERFAMILY SSF54680 329 416 5.36E-22 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 Pfam PF00591 Glycosyl transferase family, a/b domain 77 281 5.0E-34 T 11-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 66 3.3E-17 T 11-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 109 124 - T 11-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 Gene3D G3DSA:3.40.1030.10 78 323 1.6E-140 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 SUPERFAMILY SSF47648 1 69 1.31E-16 T 11-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 337 406 1.9E-20 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 PIRSF PIRSF000478 1 421 1.9E-149 T 11-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_0226 b2678d9bddf0694ce332547eddfa54de 423 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 397 8.3E-160 T 11-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_1118 3838ccb05b15b89b54cd6c78e0e87c64 165 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 6 163 17.376 T 11-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TO73_1118 3838ccb05b15b89b54cd6c78e0e87c64 165 Gene3D G3DSA:2.40.30.60 4 87 1.5E-36 T 11-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 TO73_1118 3838ccb05b15b89b54cd6c78e0e87c64 165 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 7 149 4.6E-27 T 11-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TO73_1118 3838ccb05b15b89b54cd6c78e0e87c64 165 SUPERFAMILY SSF50447 6 86 3.88E-6 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_1118 3838ccb05b15b89b54cd6c78e0e87c64 165 Pfam PF05239 PRC-barrel domain 90 162 2.2E-7 T 11-10-2018 IPR027275 PRC-barrel domain TO73_1118 3838ccb05b15b89b54cd6c78e0e87c64 165 Gene3D G3DSA:2.30.30.240 88 158 3.6E-30 T 11-10-2018 TO73_1118 3838ccb05b15b89b54cd6c78e0e87c64 165 SUPERFAMILY SSF50346 92 162 1.0E-10 T 11-10-2018 IPR011033 PRC-barrel-like superfamily TO73_0732 cfbe55f838508087ce79020c83700754 148 Pfam PF00582 Universal stress protein family 5 142 2.1E-29 T 11-10-2018 IPR006016 UspA TO73_0732 cfbe55f838508087ce79020c83700754 148 SUPERFAMILY SSF52402 4 143 4.1E-35 T 11-10-2018 TO73_0732 cfbe55f838508087ce79020c83700754 148 PRINTS PR01438 Universal stress protein signature 120 142 4.4E-17 T 11-10-2018 IPR006015 Universal stress protein A TO73_0732 cfbe55f838508087ce79020c83700754 148 PRINTS PR01438 Universal stress protein signature 102 114 4.4E-17 T 11-10-2018 IPR006015 Universal stress protein A TO73_0732 cfbe55f838508087ce79020c83700754 148 PRINTS PR01438 Universal stress protein signature 2 20 4.4E-17 T 11-10-2018 IPR006015 Universal stress protein A TO73_0732 cfbe55f838508087ce79020c83700754 148 Gene3D G3DSA:3.40.50.12370 4 148 1.6E-35 T 11-10-2018 TO73_1395 25d381ffbde14fe3aae4643a1db8b74c 330 Pfam PF01008 Initiation factor 2 subunit family 48 317 6.5E-68 T 11-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TO73_1395 25d381ffbde14fe3aae4643a1db8b74c 330 Gene3D G3DSA:3.40.50.10470 133 329 5.0E-66 T 11-10-2018 TO73_1395 25d381ffbde14fe3aae4643a1db8b74c 330 SUPERFAMILY SSF100950 12 319 3.35E-109 T 11-10-2018 IPR037171 NagB/RpiA transferase-like TO73_1395 25d381ffbde14fe3aae4643a1db8b74c 330 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 13 316 1.3E-120 T 11-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TO73_1395 25d381ffbde14fe3aae4643a1db8b74c 330 Gene3D G3DSA:1.20.120.420 6 130 1.0E-32 T 11-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TO73_1395 25d381ffbde14fe3aae4643a1db8b74c 330 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 3 327 39.569 T 11-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TO73_1395 25d381ffbde14fe3aae4643a1db8b74c 330 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 34 317 2.2E-99 T 11-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TO73_1817 83d682c530e5ef5a936c8da345c7b30c 285 SUPERFAMILY SSF51569 3 279 5.68E-42 T 11-10-2018 TO73_1817 83d682c530e5ef5a936c8da345c7b30c 285 Gene3D G3DSA:3.20.20.70 1 283 7.2E-85 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1817 83d682c530e5ef5a936c8da345c7b30c 285 Pfam PF00682 HMGL-like 10 272 6.7E-22 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TO73_1879 42dd82e7f52bfda77dfb12e47028e8d1 197 SUPERFAMILY SSF46689 3 85 2.0E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_1879 42dd82e7f52bfda77dfb12e47028e8d1 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 9.0E-15 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_1879 42dd82e7f52bfda77dfb12e47028e8d1 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 6.7E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_1879 42dd82e7f52bfda77dfb12e47028e8d1 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 6.7E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_1879 42dd82e7f52bfda77dfb12e47028e8d1 197 Gene3D G3DSA:1.10.357.10 2 197 1.4E-67 T 11-10-2018 TO73_1879 42dd82e7f52bfda77dfb12e47028e8d1 197 SUPERFAMILY SSF48498 82 194 1.27E-6 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TO73_1473 ecc3569dc9bae5952669586c2ccbe330 447 SUPERFAMILY SSF55103 210 447 2.13E-64 T 11-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TO73_1473 ecc3569dc9bae5952669586c2ccbe330 447 Gene3D G3DSA:3.30.70.2740 325 405 4.3E-15 T 11-10-2018 TO73_1473 ecc3569dc9bae5952669586c2ccbe330 447 Gene3D G3DSA:1.10.45.10 406 446 7.5E-14 T 11-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TO73_1473 ecc3569dc9bae5952669586c2ccbe330 447 Pfam PF01565 FAD binding domain 38 175 1.1E-41 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TO73_1473 ecc3569dc9bae5952669586c2ccbe330 447 Pfam PF02913 FAD linked oxidases, C-terminal domain 206 445 1.2E-68 T 11-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TO73_1473 ecc3569dc9bae5952669586c2ccbe330 447 SUPERFAMILY SSF56176 6 207 1.68E-61 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TO73_1473 ecc3569dc9bae5952669586c2ccbe330 447 Gene3D G3DSA:3.30.465.40 3 224 3.3E-63 T 11-10-2018 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 SUPERFAMILY SSF54980 402 480 4.32E-26 T 11-10-2018 IPR035647 EF-G domain III/V-like TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 SUPERFAMILY SSF54980 603 689 3.79E-34 T 11-10-2018 IPR035647 EF-G domain III/V-like TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 SMART SM00838 600 687 1.8E-60 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 TIGRFAM TIGR00484 EF-G: translation elongation factor G 6 689 0.0 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 181 6.2E-33 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 SUPERFAMILY SSF54211 479 599 1.31E-49 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Pfam PF14492 Elongation Factor G, domain II 404 478 5.1E-36 T 11-10-2018 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Gene3D G3DSA:3.30.70.240 604 674 3.2E-99 T 11-10-2018 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 SUPERFAMILY SSF52540 7 282 3.56E-110 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Gene3D G3DSA:3.30.70.870 405 483 2.0E-34 T 11-10-2018 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Hamap MF_00054_B Elongation factor G [fusA]. 8 691 114.007 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 SUPERFAMILY SSF50447 265 396 2.59E-36 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Pfam PF03144 Elongation factor Tu domain 2 323 389 1.4E-15 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 PRINTS PR00315 GTP-binding elongation factor signature 132 141 4.5E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.5E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 PRINTS PR00315 GTP-binding elongation factor signature 96 107 4.5E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 PRINTS PR00315 GTP-binding elongation factor signature 60 68 4.5E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 PRINTS PR00315 GTP-binding elongation factor signature 80 90 4.5E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Pfam PF03764 Elongation factor G, domain IV 479 597 3.0E-51 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Gene3D G3DSA:3.40.50.300 1 286 1.6E-111 T 11-10-2018 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Pfam PF00009 Elongation factor Tu GTP binding domain 10 282 2.9E-68 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 SMART SM00889 480 598 2.6E-78 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Pfam PF00679 Elongation factor G C-terminus 600 686 4.9E-34 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Gene3D G3DSA:3.30.230.10 484 687 3.2E-99 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0373 3b1c4ad793b562a36885acb2da0f0daa 691 Gene3D G3DSA:2.40.30.10 288 400 2.2E-43 T 11-10-2018 TO73_1162 099191da75c8ffcc04865a83a34c132a 133 SUPERFAMILY SSF49764 26 127 9.07E-22 T 11-10-2018 IPR008978 HSP20-like chaperone TO73_1162 099191da75c8ffcc04865a83a34c132a 133 Gene3D G3DSA:2.60.40.790 3 130 1.9E-23 T 11-10-2018 IPR008978 HSP20-like chaperone TO73_1162 099191da75c8ffcc04865a83a34c132a 133 Pfam PF00011 Hsp20/alpha crystallin family 42 126 3.1E-11 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 Gene3D G3DSA:3.30.70.890 153 278 5.8E-38 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 TIGRFAM TIGR00191 thrB: homoserine kinase 7 272 2.3E-65 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 Pfam PF08544 GHMP kinases C terminal 201 269 6.2E-10 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 Pfam PF00288 GHMP kinases N terminal domain 79 138 1.5E-10 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 Gene3D G3DSA:3.30.230.10 6 149 3.7E-40 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 84 95 - T 11-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 PRINTS PR00958 Homoserine kinase signature 91 106 2.6E-33 T 11-10-2018 TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 PRINTS PR00958 Homoserine kinase signature 125 138 2.6E-33 T 11-10-2018 TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 PRINTS PR00958 Homoserine kinase signature 12 27 2.6E-33 T 11-10-2018 TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 PRINTS PR00958 Homoserine kinase signature 241 256 2.6E-33 T 11-10-2018 TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 PRINTS PR00958 Homoserine kinase signature 162 179 2.6E-33 T 11-10-2018 TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 SUPERFAMILY SSF55060 158 274 6.04E-31 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 PIRSF PIRSF000676 5 283 1.0E-73 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 SUPERFAMILY SSF54211 6 148 5.54E-27 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0538 7e237b0e2260a0cf7ae0b787daa72265 292 Hamap MF_00384 Homoserine kinase [thrB]. 7 291 27.719 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TO73_1058 b40c9cfd2eb7233578eaf59f75f35127 341 Pfam PF01430 Hsp33 protein 4 287 6.8E-79 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TO73_1058 b40c9cfd2eb7233578eaf59f75f35127 341 PIRSF PIRSF005261 1 300 4.9E-68 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TO73_1058 b40c9cfd2eb7233578eaf59f75f35127 341 SUPERFAMILY SSF118352 240 298 2.62E-19 T 11-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 TO73_1058 b40c9cfd2eb7233578eaf59f75f35127 341 Gene3D G3DSA:3.55.30.10 1 228 1.6E-79 T 11-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 TO73_1058 b40c9cfd2eb7233578eaf59f75f35127 341 Gene3D G3DSA:3.90.1280.10 239 300 9.3E-17 T 11-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 TO73_1058 b40c9cfd2eb7233578eaf59f75f35127 341 SUPERFAMILY SSF64397 4 250 1.83E-62 T 11-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 TO73_1058 b40c9cfd2eb7233578eaf59f75f35127 341 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 299 34.185 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TO73_0711 b375d1e46b2e814709b9ea83382bb742 265 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 261 6.3E-65 T 11-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TO73_0711 b375d1e46b2e814709b9ea83382bb742 265 Gene3D G3DSA:3.40.50.10860 5 245 2.5E-92 T 11-10-2018 TO73_0711 b375d1e46b2e814709b9ea83382bb742 265 SUPERFAMILY SSF53223 2 99 1.04E-26 T 11-10-2018 TO73_0711 b375d1e46b2e814709b9ea83382bb742 265 SUPERFAMILY SSF51735 100 261 3.71E-41 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0711 b375d1e46b2e814709b9ea83382bb742 265 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 119 170 2.8E-6 T 11-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TO73_0711 b375d1e46b2e814709b9ea83382bb742 265 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 259 31.095 T 11-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TO73_0711 b375d1e46b2e814709b9ea83382bb742 265 Gene3D G3DSA:3.40.50.720 100 235 2.5E-92 T 11-10-2018 TO73_0711 b375d1e46b2e814709b9ea83382bb742 265 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 87 2.7E-24 T 11-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 Gene3D G3DSA:3.50.50.60 1 214 1.3E-73 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 Gene3D G3DSA:3.50.50.60 301 451 1.6E-47 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 3 594 4.2E-204 T 11-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 SMART SM01228 519 590 8.4E-36 T 11-10-2018 TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 Gene3D G3DSA:1.10.150.570 542 595 4.0E-19 T 11-10-2018 TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 266 280 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 Gene3D G3DSA:1.10.10.1800 468 541 1.7E-7 T 11-10-2018 TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 361 384 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 Pfam PF01134 Glucose inhibited division protein A 4 390 2.8E-139 T 11-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 SUPERFAMILY SSF51905 1 253 1.49E-35 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 1 596 36.996 T 11-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 TO73_2392 613bdf116b9e0d33227ab8378cd97203 596 Pfam PF13932 GidA associated domain 395 589 1.6E-59 T 11-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 Gene3D G3DSA:1.10.287.130 215 290 3.8E-16 T 11-10-2018 TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 3.1E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 3.1E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 291 2.9E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 SUPERFAMILY SSF47384 215 292 1.84E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 SMART SM00388 230 291 5.4E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 Gene3D G3DSA:3.30.565.10 300 423 2.6E-22 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 320 418 1.6E-11 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 SMART SM00387 319 420 2.3E-19 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_0499 06ca6f1494f3e221c3d762b3d02f257b 433 SUPERFAMILY SSF55874 314 420 4.06E-24 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1505 d2241ba12149d03618b0e71ef9115ae4 496 SMART SM01329 21 351 5.9E-163 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TO73_1505 d2241ba12149d03618b0e71ef9115ae4 496 Gene3D G3DSA:3.30.70.1570 386 496 1.8E-43 T 11-10-2018 TO73_1505 d2241ba12149d03618b0e71ef9115ae4 496 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 351 1.0E-113 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TO73_1505 d2241ba12149d03618b0e71ef9115ae4 496 SUPERFAMILY SSF53659 18 355 1.48E-118 T 11-10-2018 TO73_1505 d2241ba12149d03618b0e71ef9115ae4 496 Gene3D G3DSA:3.40.718.10 1 385 4.0E-169 T 11-10-2018 TO73_1505 d2241ba12149d03618b0e71ef9115ae4 496 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TO73_2277 15172467b9930817cb69232e381fd5fc 264 Gene3D G3DSA:3.40.830.10 2 263 1.7E-53 T 11-10-2018 TO73_2277 15172467b9930817cb69232e381fd5fc 264 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 5 260 1.3E-68 T 11-10-2018 TO73_2277 15172467b9930817cb69232e381fd5fc 264 Hamap MF_00055 MEMO1 family protein . 3 262 45.039 T 11-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TO73_2277 15172467b9930817cb69232e381fd5fc 264 Pfam PF01875 Memo-like protein 7 259 1.3E-44 T 11-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TO73_2344 9988325ff9e6ba8f81a28bf1fe47ad05 512 Gene3D G3DSA:3.30.565.60 214 372 9.4E-44 T 11-10-2018 IPR038475 RecG, C-terminal domain superfamily TO73_2344 9988325ff9e6ba8f81a28bf1fe47ad05 512 Pfam PF04326 Putative DNA-binding domain 28 104 1.7E-6 T 11-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 TO73_2344 9988325ff9e6ba8f81a28bf1fe47ad05 512 SUPERFAMILY SSF46785 379 450 4.92E-8 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_2344 9988325ff9e6ba8f81a28bf1fe47ad05 512 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 288 372 1.2E-21 T 11-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain TO73_2344 9988325ff9e6ba8f81a28bf1fe47ad05 512 Gene3D G3DSA:3.30.950.30 10 120 4.0E-10 T 11-10-2018 IPR038461 Schlafen, AAA domain superfamily TO73_2344 9988325ff9e6ba8f81a28bf1fe47ad05 512 Pfam PF02082 Transcriptional regulator 395 453 4.6E-5 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type TO73_2344 9988325ff9e6ba8f81a28bf1fe47ad05 512 Gene3D G3DSA:1.10.10.10 395 453 2.6E-7 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 SUPERFAMILY SSF52518 122 501 4.97E-72 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 SUPERFAMILY SSF52922 776 863 7.85E-6 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 Gene3D G3DSA:3.40.50.12470 517 774 2.0E-156 T 11-10-2018 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 PIRSF PIRSF000157 2 894 0.0 T 11-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 Gene3D G3DSA:3.40.50.970 133 489 1.3E-129 T 11-10-2018 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 7 892 9.7E-296 T 11-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 Gene3D G3DSA:1.10.287.1150 60 132 6.4E-10 T 11-10-2018 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 SUPERFAMILY SSF52518 541 758 1.77E-47 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 Pfam PF00676 Dehydrogenase E1 component 177 488 1.2E-43 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 757 893 5.5E-38 T 11-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 Pfam PF02779 Transketolase, pyrimidine binding domain 558 753 5.7E-61 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 7 36 3.0E-9 T 11-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 Gene3D G3DSA:3.40.50.11610 695 891 2.0E-156 T 11-10-2018 TO73_0154 4a88389cd8b4e48e6fbadf87f49e7efb 894 SMART SM00861 559 752 1.7E-54 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 SUPERFAMILY SSF89550 338 571 3.01E-49 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 SMART SM00278 53 72 0.0052 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 SMART SM00278 93 112 0.018 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 SMART SM00278 128 147 0.17 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 Pfam PF14520 Helix-hairpin-helix domain 94 148 1.6E-14 T 11-10-2018 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 Gene3D G3DSA:1.10.150.20 88 155 2.2E-21 T 11-10-2018 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 SUPERFAMILY SSF47781 94 147 6.67E-8 T 11-10-2018 IPR010994 RuvA domain 2-like TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 Gene3D G3DSA:3.20.20.140 327 575 5.3E-73 T 11-10-2018 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 Gene3D G3DSA:3.30.210.10 262 326 1.2E-25 T 11-10-2018 IPR037160 DNA polymerase, thumb domain superfamily TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 Pfam PF14791 DNA polymerase beta thumb 256 315 4.9E-17 T 11-10-2018 IPR029398 DNA polymerase beta, thumb domain TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 Pfam PF02811 PHP domain 340 421 5.4E-7 T 11-10-2018 IPR004013 PHP domain GO:0003824 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 Pfam PF14716 Helix-hairpin-helix domain 3 73 2.4E-19 T 11-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 PIRSF PIRSF005047 1 573 4.9E-224 T 11-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 240 248 9.2E-9 T 11-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 297 314 9.2E-9 T 11-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 60 77 9.2E-9 T 11-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 255 262 9.2E-9 T 11-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 SMART SM00481 339 418 2.8E-15 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 Gene3D G3DSA:3.30.460.10 157 261 1.4E-25 T 11-10-2018 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 SUPERFAMILY SSF81301 157 315 9.16E-40 T 11-10-2018 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 SMART SM00483 1 315 4.6E-30 T 11-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 SUPERFAMILY SSF47802 1 85 5.1E-19 T 11-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily TO73_1049 ec54ee4459fbc78ffffce040fb1558c0 575 Gene3D G3DSA:1.10.150.110 1 87 1.7E-24 T 11-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 Pfam PF00571 CBS domain 130 189 3.9E-4 T 11-10-2018 IPR000644 CBS domain TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 Gene3D G3DSA:3.10.580.10 127 252 1.6E-23 T 11-10-2018 TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 Pfam PF03448 MgtE intracellular N domain 28 127 1.7E-21 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 Pfam PF01769 Divalent cation transporter 320 442 7.1E-27 T 11-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 Gene3D G3DSA:1.25.60.10 4 125 2.4E-20 T 11-10-2018 IPR038076 MgtE, N-terminal domain superfamily TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 SUPERFAMILY SSF54631 130 249 1.39E-18 T 11-10-2018 TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 SMART SM00924 27 130 8.5E-25 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 Gene3D G3DSA:1.10.357.20 270 449 9.2E-48 T 11-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 SUPERFAMILY SSF158791 5 127 3.53E-24 T 11-10-2018 TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 TIGRFAM TIGR00400 mgtE: magnesium transporter 4 450 1.8E-92 T 11-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 TO73_1670 3bcf646d6854952878bd0d1fa906fd47 454 SUPERFAMILY SSF161093 279 449 7.19E-41 T 11-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TO73_1022 bb58d74e6ad66097da6327339fc8f149 84 SUPERFAMILY SSF47598 1 42 2.54E-6 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TO73_1022 bb58d74e6ad66097da6327339fc8f149 84 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 40 8.1E-8 T 11-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TO73_0594 981f90b2ad9a36e4e90c961e36309186 394 SUPERFAMILY SSF53244 265 381 2.98E-16 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_0594 981f90b2ad9a36e4e90c961e36309186 394 Gene3D G3DSA:3.40.1190.10 1 264 1.5E-69 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_0594 981f90b2ad9a36e4e90c961e36309186 394 SUPERFAMILY SSF53623 1 262 1.83E-65 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_0594 981f90b2ad9a36e4e90c961e36309186 394 Pfam PF08245 Mur ligase middle domain 115 179 8.2E-6 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TO73_0594 981f90b2ad9a36e4e90c961e36309186 394 Gene3D G3DSA:3.90.190.20 267 383 1.1E-14 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_0594 981f90b2ad9a36e4e90c961e36309186 394 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 380 4.4E-79 T 11-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 74 230 2.1E-33 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Gene3D G3DSA:3.40.50.300 69 240 8.5E-76 T 11-10-2018 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Pfam PF00009 Elongation factor Tu GTP binding domain 76 232 1.3E-35 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 SUPERFAMILY SSF52156 356 480 1.57E-32 T 11-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 SUPERFAMILY SSF50447 244 326 7.46E-20 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 48 4.5E-16 T 11-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Gene3D G3DSA:2.40.30.10 241 363 1.0E-42 T 11-10-2018 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Pfam PF11987 Translation-initiation factor 2 361 462 1.6E-30 T 11-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 571 14.567 T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Gene3D G3DSA:2.40.30.10 475 571 3.6E-35 T 11-10-2018 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Gene3D G3DSA:3.40.50.10050 367 474 4.0E-35 T 11-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Pfam PF03144 Elongation factor Tu domain 2 495 561 4.1E-7 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 3 569 1.2E-205 T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 Gene3D G3DSA:1.10.10.2480 1 68 4.6E-28 T 11-10-2018 TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 SUPERFAMILY SSF50447 474 569 7.28E-31 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 SUPERFAMILY SSF52540 55 243 4.12E-52 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0687 6a1fde5406b4921b788b06360adc8c0d 571 ProSitePatterns PS01176 Initiation factor 2 signature. 524 546 - T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TO73_0644 62bc4e7cadf34aaed896e17e95f0b09e 140 Gene3D G3DSA:1.20.1550.10 3 124 7.3E-8 T 11-10-2018 IPR023380 DsbB-like superfamily TO73_0644 62bc4e7cadf34aaed896e17e95f0b09e 140 PIRSF PIRSF036659 4 138 7.6E-40 T 11-10-2018 IPR012187 Disulphide bond formation protein BdbC TO73_0644 62bc4e7cadf34aaed896e17e95f0b09e 140 SUPERFAMILY SSF158442 13 131 1.57E-24 T 11-10-2018 IPR023380 DsbB-like superfamily TO73_0644 62bc4e7cadf34aaed896e17e95f0b09e 140 Pfam PF02600 Disulfide bond formation protein DsbB 11 111 1.9E-8 T 11-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 TO73_2095 bca60e5485133bb452289efd0bf83374 630 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 78 345 5.6E-42 T 11-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TO73_2095 bca60e5485133bb452289efd0bf83374 630 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 100 118 - T 11-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site TO73_2095 bca60e5485133bb452289efd0bf83374 630 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 5 630 39.952 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 TIGRFAM TIGR01273 speA: arginine decarboxylase 9 629 2.9E-211 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01180 Arginine decarboxylase signature 148 163 2.4E-63 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01180 Arginine decarboxylase signature 462 483 2.4E-63 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01180 Arginine decarboxylase signature 487 512 2.4E-63 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01180 Arginine decarboxylase signature 540 561 2.4E-63 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01180 Arginine decarboxylase signature 198 220 2.4E-63 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01180 Arginine decarboxylase signature 92 106 2.4E-63 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01180 Arginine decarboxylase signature 174 195 2.4E-63 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01180 Arginine decarboxylase signature 68 83 2.4E-63 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01180 Arginine decarboxylase signature 325 342 2.4E-63 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PIRSF PIRSF001336 1 630 3.1E-244 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TO73_2095 bca60e5485133bb452289efd0bf83374 630 Gene3D G3DSA:3.20.20.10 69 350 1.2E-216 T 11-10-2018 IPR029066 PLP-binding barrel TO73_2095 bca60e5485133bb452289efd0bf83374 630 Gene3D G3DSA:2.40.37.10 16 567 1.2E-216 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TO73_2095 bca60e5485133bb452289efd0bf83374 630 SUPERFAMILY SSF51419 68 347 1.16E-64 T 11-10-2018 IPR029066 PLP-binding barrel TO73_2095 bca60e5485133bb452289efd0bf83374 630 SUPERFAMILY SSF50621 458 567 4.71E-10 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TO73_2095 bca60e5485133bb452289efd0bf83374 630 Gene3D G3DSA:1.20.58.930 368 458 1.2E-216 T 11-10-2018 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 241 254 1.1E-18 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 540 553 1.1E-18 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 100 118 1.1E-18 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 335 354 1.1E-18 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TO73_2095 bca60e5485133bb452289efd0bf83374 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 124 136 1.1E-18 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TO73_1710 4eebbc928fdcc04494dc53aa20206ddb 451 Gene3D G3DSA:1.10.3110.10 100 192 1.7E-120 T 11-10-2018 TO73_1710 4eebbc928fdcc04494dc53aa20206ddb 451 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 445 1.3E-77 T 11-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TO73_1710 4eebbc928fdcc04494dc53aa20206ddb 451 Pfam PF01593 Flavin containing amine oxidoreductase 12 441 1.5E-64 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TO73_1710 4eebbc928fdcc04494dc53aa20206ddb 451 SUPERFAMILY SSF54373 293 392 4.32E-20 T 11-10-2018 TO73_1710 4eebbc928fdcc04494dc53aa20206ddb 451 Gene3D G3DSA:3.90.660.20 34 392 1.7E-120 T 11-10-2018 TO73_1710 4eebbc928fdcc04494dc53aa20206ddb 451 SUPERFAMILY SSF51905 4 440 5.7E-58 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1710 4eebbc928fdcc04494dc53aa20206ddb 451 Gene3D G3DSA:3.50.50.60 5 434 1.7E-120 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0268 99192be8d3cf439f2be5b944efe2bc74 326 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 324 1.0E-93 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 TO73_0268 99192be8d3cf439f2be5b944efe2bc74 326 SUPERFAMILY SSF53659 1 324 6.58E-88 T 11-10-2018 TO73_0268 99192be8d3cf439f2be5b944efe2bc74 326 Pfam PF02504 Fatty acid synthesis protein 1 316 3.6E-99 T 11-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 TO73_0268 99192be8d3cf439f2be5b944efe2bc74 326 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 326 126.886 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 TO73_0268 99192be8d3cf439f2be5b944efe2bc74 326 PIRSF PIRSF002465 1 326 9.6E-109 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 TO73_0268 99192be8d3cf439f2be5b944efe2bc74 326 Gene3D G3DSA:3.40.718.10 1 325 4.0E-118 T 11-10-2018 TO73_1342 6447980a340cd80973de4841a3bcc0db 170 Pfam PF13710 ACT domain 12 73 2.3E-15 T 11-10-2018 TO73_1342 6447980a340cd80973de4841a3bcc0db 170 SUPERFAMILY SSF55021 2 76 2.29E-20 T 11-10-2018 TO73_1342 6447980a340cd80973de4841a3bcc0db 170 Gene3D G3DSA:3.30.70.1150 82 163 5.6E-30 T 11-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal TO73_1342 6447980a340cd80973de4841a3bcc0db 170 Gene3D G3DSA:3.30.70.260 1 78 1.5E-33 T 11-10-2018 TO73_1342 6447980a340cd80973de4841a3bcc0db 170 Pfam PF10369 Small subunit of acetolactate synthase 83 157 4.6E-28 T 11-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TO73_1342 6447980a340cd80973de4841a3bcc0db 170 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 75 2.0E-34 T 11-10-2018 TO73_1342 6447980a340cd80973de4841a3bcc0db 170 SUPERFAMILY SSF55021 78 162 8.4E-27 T 11-10-2018 TO73_1342 6447980a340cd80973de4841a3bcc0db 170 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 158 1.4E-60 T 11-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TO73_0578 b99cff5ba28239c70a2ca41e71f6f6bc 225 SUPERFAMILY SSF52172 1 177 1.18E-38 T 11-10-2018 IPR011006 CheY-like superfamily TO73_0578 b99cff5ba28239c70a2ca41e71f6f6bc 225 Gene3D G3DSA:3.40.50.2300 1 121 7.6E-35 T 11-10-2018 TO73_0578 b99cff5ba28239c70a2ca41e71f6f6bc 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 218 3.5E-25 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_0578 b99cff5ba28239c70a2ca41e71f6f6bc 225 SMART SM00862 143 218 1.4E-27 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_0578 b99cff5ba28239c70a2ca41e71f6f6bc 225 Pfam PF00072 Response regulator receiver domain 4 113 1.1E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_0578 b99cff5ba28239c70a2ca41e71f6f6bc 225 SMART SM00448 2 112 6.0E-38 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_0578 b99cff5ba28239c70a2ca41e71f6f6bc 225 Gene3D G3DSA:1.10.10.10 122 221 8.3E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1318 cac5215449c1df4b6d7606652426f04f 576 SUPERFAMILY SSF56519 41 211 8.76E-27 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TO73_1318 cac5215449c1df4b6d7606652426f04f 576 Gene3D G3DSA:3.90.1310.30 41 210 9.3E-21 T 11-10-2018 TO73_1318 cac5215449c1df4b6d7606652426f04f 576 Gene3D G3DSA:3.40.710.10 211 574 1.8E-86 T 11-10-2018 TO73_1318 cac5215449c1df4b6d7606652426f04f 576 SUPERFAMILY SSF56601 163 572 9.68E-81 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TO73_1318 cac5215449c1df4b6d7606652426f04f 576 Pfam PF03717 Penicillin-binding Protein dimerisation domain 98 196 6.2E-12 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TO73_1318 cac5215449c1df4b6d7606652426f04f 576 Pfam PF00905 Penicillin binding protein transpeptidase domain 248 567 1.7E-50 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TO73_0750 55422935db873ac8eab470398cf99fc3 445 Gene3D G3DSA:3.30.470.130 1 445 3.4E-195 T 11-10-2018 TO73_0750 55422935db873ac8eab470398cf99fc3 445 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 442 3.7E-206 T 11-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 TO73_0750 55422935db873ac8eab470398cf99fc3 445 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 317 8.9E-76 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TO73_0750 55422935db873ac8eab470398cf99fc3 445 Pfam PF02785 Biotin carboxylase C-terminal domain 332 440 1.2E-39 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TO73_0750 55422935db873ac8eab470398cf99fc3 445 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 282 289 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TO73_0750 55422935db873ac8eab470398cf99fc3 445 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.0E-42 T 11-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TO73_0750 55422935db873ac8eab470398cf99fc3 445 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 151 165 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TO73_0750 55422935db873ac8eab470398cf99fc3 445 SUPERFAMILY SSF51246 327 444 1.31E-42 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TO73_0750 55422935db873ac8eab470398cf99fc3 445 SMART SM00878 332 440 6.9E-66 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TO73_0750 55422935db873ac8eab470398cf99fc3 445 SUPERFAMILY SSF52440 1 112 2.16E-46 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TO73_0750 55422935db873ac8eab470398cf99fc3 445 SUPERFAMILY SSF56059 82 344 2.47E-74 T 11-10-2018 TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 Pfam PF13522 Glutamine amidotransferase domain 64 182 2.0E-25 T 11-10-2018 TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 Gene3D G3DSA:3.40.50.10490 245 603 2.4E-144 T 11-10-2018 TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 604 4.3E-255 T 11-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 Gene3D G3DSA:3.40.50.10490 442 589 2.4E-144 T 11-10-2018 TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 Gene3D G3DSA:3.60.20.10 2 238 4.9E-77 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 604 42.143 T 11-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 SUPERFAMILY SSF53697 243 604 4.1E-111 T 11-10-2018 TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 Pfam PF01380 SIS domain 457 586 5.2E-23 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 Pfam PF01380 SIS domain 289 412 1.3E-24 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TO73_2304 c5c528e6c07cea91fa013de90c90b2cf 604 SUPERFAMILY SSF56235 2 231 2.83E-71 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_1483 09fb8fe883344642bf0431ca140660ee 385 Gene3D G3DSA:1.20.140.10 237 385 1.1E-37 T 11-10-2018 TO73_1483 09fb8fe883344642bf0431ca140660ee 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 379 1.5E-29 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TO73_1483 09fb8fe883344642bf0431ca140660ee 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 220 4.1E-22 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TO73_1483 09fb8fe883344642bf0431ca140660ee 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_1483 09fb8fe883344642bf0431ca140660ee 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 124 2.7E-34 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TO73_1483 09fb8fe883344642bf0431ca140660ee 385 SUPERFAMILY SSF56645 3 231 5.63E-74 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_1483 09fb8fe883344642bf0431ca140660ee 385 SUPERFAMILY SSF47203 232 382 3.29E-39 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_1483 09fb8fe883344642bf0431ca140660ee 385 Gene3D G3DSA:2.40.110.10 127 231 4.6E-33 T 11-10-2018 TO73_1483 09fb8fe883344642bf0431ca140660ee 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_1483 09fb8fe883344642bf0431ca140660ee 385 Gene3D G3DSA:1.10.540.10 1 125 1.2E-40 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TO73_0454 2f76e5374d0086469864fbdd5916e74c 224 SUPERFAMILY SSF69618 1 223 2.88E-42 T 11-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_0454 2f76e5374d0086469864fbdd5916e74c 224 Pfam PF02602 Uroporphyrinogen-III synthase HemD 11 215 1.2E-42 T 11-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_0454 2f76e5374d0086469864fbdd5916e74c 224 Gene3D G3DSA:3.40.50.10090 1 112 9.2E-15 T 11-10-2018 TO73_0454 2f76e5374d0086469864fbdd5916e74c 224 Gene3D G3DSA:3.40.50.10090 113 220 1.0E-16 T 11-10-2018 TO73_2394 b722a16bce9f7105def002719b7230f3 306 Pfam PF00881 Nitroreductase family 8 161 9.6E-22 T 11-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TO73_2394 b722a16bce9f7105def002719b7230f3 306 SUPERFAMILY SSF55469 1 216 3.27E-55 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TO73_2394 b722a16bce9f7105def002719b7230f3 306 Gene3D G3DSA:3.40.109.10 2 239 1.3E-56 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TO73_0772 f03e5d3e207d105e1ddcbd8268d52ad0 287 Gene3D G3DSA:1.20.5.1230 158 275 4.1E-11 T 11-10-2018 TO73_0772 f03e5d3e207d105e1ddcbd8268d52ad0 287 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 8 268 7.0E-7 T 11-10-2018 TO73_0772 f03e5d3e207d105e1ddcbd8268d52ad0 287 SUPERFAMILY SSF58113 7 173 4.77E-14 T 11-10-2018 TO73_0772 f03e5d3e207d105e1ddcbd8268d52ad0 287 SUPERFAMILY SSF47162 186 260 7.32E-6 T 11-10-2018 TO73_0772 f03e5d3e207d105e1ddcbd8268d52ad0 287 Pfam PF01442 Apolipoprotein A1/A4/E domain 175 260 1.1E-8 T 11-10-2018 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-8963901 TO73_0772 f03e5d3e207d105e1ddcbd8268d52ad0 287 Pfam PF01442 Apolipoprotein A1/A4/E domain 17 198 2.9E-21 T 11-10-2018 IPR000074 Apolipoprotein A/E GO:0005576|GO:0006869|GO:0008289|GO:0042157 Reactome: R-HSA-8963901 TO73_0772 f03e5d3e207d105e1ddcbd8268d52ad0 287 Gene3D G3DSA:1.20.120.20 3 157 5.3E-18 T 11-10-2018 TO73_0401 c1fcd3590fd64a86a107847ae3971361 126 Gene3D G3DSA:4.10.910.10 73 126 3.1E-29 T 11-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0401 c1fcd3590fd64a86a107847ae3971361 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.2E-32 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0401 c1fcd3590fd64a86a107847ae3971361 126 Gene3D G3DSA:1.10.8.50 1 72 1.3E-30 T 11-10-2018 TO73_0401 c1fcd3590fd64a86a107847ae3971361 126 PIRSF PIRSF002134 1 125 1.0E-46 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0401 c1fcd3590fd64a86a107847ae3971361 126 SUPERFAMILY SSF46946 2 123 7.59E-49 T 11-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TO73_0401 c1fcd3590fd64a86a107847ae3971361 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 11-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0401 c1fcd3590fd64a86a107847ae3971361 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.207 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0401 c1fcd3590fd64a86a107847ae3971361 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 4.1E-54 T 11-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 117 201 1.0E-14 T 11-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 SUPERFAMILY SSF141734 4 106 5.62E-45 T 11-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 112 198 19.903 T 11-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 4 203 35.689 T 11-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 Gene3D G3DSA:3.10.20.400 1 92 7.9E-39 T 11-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 2 105 30.356 T 11-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 115 198 4.4E-28 T 11-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 51 105 2.0E-23 T 11-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 SUPERFAMILY SSF101386 115 203 2.06E-24 T 11-10-2018 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 Gene3D G3DSA:1.10.287.1080 113 204 1.2E-27 T 11-10-2018 TO73_1522 b7353ccec764257a7fc16ec6fa6e463a 209 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 101 7.8E-33 T 11-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TO73_1834 a35a191083e62e2759d31d688efd05f3 406 Gene3D G3DSA:3.40.50.10180 33 244 2.0E-112 T 11-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 TO73_1834 a35a191083e62e2759d31d688efd05f3 406 Pfam PF05161 MOFRL family 301 399 9.5E-30 T 11-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 TO73_1834 a35a191083e62e2759d31d688efd05f3 406 Pfam PF13660 Domain of unknown function (DUF4147) 5 211 9.5E-60 T 11-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 TO73_1834 a35a191083e62e2759d31d688efd05f3 406 SUPERFAMILY SSF82544 3 405 3.53E-116 T 11-10-2018 TO73_1834 a35a191083e62e2759d31d688efd05f3 406 Gene3D G3DSA:3.40.1480.10 245 401 2.0E-112 T 11-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily TO73_1836 5de64d0279ff3c37300e131617525c98 129 Pfam PF11497 NADH-quinone oxidoreductase chain 15 5 125 2.1E-60 T 11-10-2018 IPR021093 NADH-quinone oxidoreductase, subunit15 KEGG: 00190+1.6.5.11 TO73_1836 5de64d0279ff3c37300e131617525c98 129 Gene3D G3DSA:3.30.920.80 1 129 1.7E-75 T 11-10-2018 IPR038458 NADH-quinone oxidoreductase, subunit 15 superfamily KEGG: 00190+1.6.5.11 TO73_1836 5de64d0279ff3c37300e131617525c98 129 SUPERFAMILY SSF55387 4 128 1.78E-65 T 11-10-2018 TO73_1282 1345de49f17bd698c217d79cf422419f 350 SUPERFAMILY SSF52540 83 320 2.16E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1282 1345de49f17bd698c217d79cf422419f 350 SUPERFAMILY SSF117916 1 78 2.98E-20 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TO73_1282 1345de49f17bd698c217d79cf422419f 350 Hamap MF_02040 Iron-sulfur cluster carrier protein. 87 336 37.572 T 11-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TO73_1282 1345de49f17bd698c217d79cf422419f 350 ProSitePatterns PS01215 Mrp family signature. 199 215 - T 11-10-2018 IPR000808 Mrp, conserved site GO:0005524 TO73_1282 1345de49f17bd698c217d79cf422419f 350 Gene3D G3DSA:3.30.300.130 1 83 1.4E-18 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TO73_1282 1345de49f17bd698c217d79cf422419f 350 Pfam PF01883 Iron-sulfur cluster assembly protein 5 70 2.0E-19 T 11-10-2018 IPR002744 MIP18 family-like TO73_1282 1345de49f17bd698c217d79cf422419f 350 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 92 335 7.2E-99 T 11-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TO73_1282 1345de49f17bd698c217d79cf422419f 350 Gene3D G3DSA:3.40.50.300 86 334 2.8E-84 T 11-10-2018 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 344 355 2.6E-20 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 221 241 2.6E-20 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 179 201 2.6E-20 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 99 113 2.6E-20 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 Gene3D G3DSA:1.10.8.1210 373 419 2.2E-7 T 11-10-2018 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 SUPERFAMILY SSF53223 13 189 6.72E-65 T 11-10-2018 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 Gene3D G3DSA:1.10.8.1210 6 39 1.0E-92 T 11-10-2018 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 42 170 4.6E-50 T 11-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 SUPERFAMILY SSF51735 188 418 6.93E-53 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 PIRSF PIRSF000185 13 419 5.8E-147 T 11-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 Gene3D G3DSA:3.40.50.720 195 345 2.5E-52 T 11-10-2018 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 Gene3D G3DSA:3.40.50.10860 40 175 1.0E-92 T 11-10-2018 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 SMART SM00839 190 416 1.5E-60 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0415 57ab9cf5508d5e013c68f8f91d858270 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 188 416 6.5E-51 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 Pfam PF01479 S4 domain 4 47 1.1E-13 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 68 221 9.8E-44 T 11-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 11-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 SUPERFAMILY SSF55174 5 80 1.38E-14 T 11-10-2018 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 SUPERFAMILY SSF55120 64 225 9.11E-41 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 Gene3D G3DSA:3.10.290.10 3 64 6.3E-15 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 Gene3D G3DSA:3.30.70.580 65 224 2.7E-51 T 11-10-2018 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 SMART SM00363 4 64 2.1E-11 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 Gene3D G3DSA:3.30.70.1560 128 208 2.7E-51 T 11-10-2018 TO73_2064 bcca87d2a58fcc98cd99df1e1035f611 236 Pfam PF00849 RNA pseudouridylate synthase 64 191 6.1E-19 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2085 17ad27688c42c375d043e881111a94a3 345 SMART SM00382 31 217 1.2E-19 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2085 17ad27688c42c375d043e881111a94a3 345 SUPERFAMILY SSF50331 254 329 1.7E-8 T 11-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TO73_2085 17ad27688c42c375d043e881111a94a3 345 SUPERFAMILY SSF52540 6 239 5.82E-82 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2085 17ad27688c42c375d043e881111a94a3 345 Pfam PF00005 ABC transporter 22 159 5.1E-36 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_2085 17ad27688c42c375d043e881111a94a3 345 Gene3D G3DSA:3.40.50.300 4 245 2.3E-75 T 11-10-2018 TO73_2085 17ad27688c42c375d043e881111a94a3 345 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_2085 17ad27688c42c375d043e881111a94a3 345 Pfam PF08402 TOBE domain 266 329 2.7E-8 T 11-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TO73_0180 8e52503a53c2ded07b447ee7d6024e07 370 Gene3D G3DSA:3.10.150.10 3 248 4.2E-71 T 11-10-2018 TO73_0180 8e52503a53c2ded07b447ee7d6024e07 370 Gene3D G3DSA:3.70.10.10 141 368 4.2E-71 T 11-10-2018 TO73_0180 8e52503a53c2ded07b447ee7d6024e07 370 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 6 369 2.1E-50 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TO73_0180 8e52503a53c2ded07b447ee7d6024e07 370 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 3 84 3.6E-7 T 11-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TO73_0180 8e52503a53c2ded07b447ee7d6024e07 370 SUPERFAMILY SSF55979 251 370 6.6E-24 T 11-10-2018 TO73_0180 8e52503a53c2ded07b447ee7d6024e07 370 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 252 368 4.7E-18 T 11-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TO73_0180 8e52503a53c2ded07b447ee7d6024e07 370 SMART SM00480 15 366 3.7E-50 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TO73_0180 8e52503a53c2ded07b447ee7d6024e07 370 SUPERFAMILY SSF55979 132 250 1.34E-16 T 11-10-2018 TO73_0180 8e52503a53c2ded07b447ee7d6024e07 370 Pfam PF02767 DNA polymerase III beta subunit, central domain 134 249 8.2E-17 T 11-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 TO73_0087 1168573ed0ea600fd389f3b4c7a587c5 125 SUPERFAMILY SSF48300 4 62 1.57E-13 T 11-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0087 1168573ed0ea600fd389f3b4c7a587c5 125 Gene3D G3DSA:1.20.5.710 3 55 2.6E-16 T 11-10-2018 TO73_0087 1168573ed0ea600fd389f3b4c7a587c5 125 Gene3D G3DSA:3.30.1390.10 56 125 6.1E-27 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TO73_0087 1168573ed0ea600fd389f3b4c7a587c5 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 125 23.042 T 11-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0087 1168573ed0ea600fd389f3b4c7a587c5 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 125 8.0E-18 T 11-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0087 1168573ed0ea600fd389f3b4c7a587c5 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 3.1E-40 T 11-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0087 1168573ed0ea600fd389f3b4c7a587c5 125 SUPERFAMILY SSF54736 55 125 2.27E-22 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TO73_0087 1168573ed0ea600fd389f3b4c7a587c5 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 5.0E-16 T 11-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0087 1168573ed0ea600fd389f3b4c7a587c5 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 125 9.4E-26 T 11-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0428 882dd2cf181bef5238e9c07ae0ba6794 248 ProSitePatterns PS00856 Guanylate kinase-like signature. 64 81 - T 11-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TO73_0428 882dd2cf181bef5238e9c07ae0ba6794 248 Gene3D G3DSA:3.30.63.10 61 120 1.1E-63 T 11-10-2018 TO73_0428 882dd2cf181bef5238e9c07ae0ba6794 248 Hamap MF_00328 Guanylate kinase [gmk]. 29 211 35.584 T 11-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TO73_0428 882dd2cf181bef5238e9c07ae0ba6794 248 Pfam PF00625 Guanylate kinase 31 209 3.4E-42 T 11-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TO73_0428 882dd2cf181bef5238e9c07ae0ba6794 248 Gene3D G3DSA:3.40.50.300 35 207 1.1E-63 T 11-10-2018 TO73_0428 882dd2cf181bef5238e9c07ae0ba6794 248 SUPERFAMILY SSF52540 29 213 2.63E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0428 882dd2cf181bef5238e9c07ae0ba6794 248 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 31 208 1.7E-68 T 11-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TO73_0428 882dd2cf181bef5238e9c07ae0ba6794 248 SMART SM00072 30 211 2.0E-68 T 11-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TO73_1472 79f78c6705e6bd902d392031b886c231 318 Pfam PF00990 Diguanylate cyclase, GGDEF domain 165 306 7.8E-41 T 11-10-2018 IPR000160 GGDEF domain TO73_1472 79f78c6705e6bd902d392031b886c231 318 SMART SM00267 155 310 1.8E-50 T 11-10-2018 IPR000160 GGDEF domain TO73_1472 79f78c6705e6bd902d392031b886c231 318 SUPERFAMILY SSF55073 166 310 5.41E-46 T 11-10-2018 IPR029787 Nucleotide cyclase TO73_1472 79f78c6705e6bd902d392031b886c231 318 Gene3D G3DSA:3.30.70.270 157 312 2.2E-52 T 11-10-2018 TO73_1472 79f78c6705e6bd902d392031b886c231 318 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 159 308 8.6E-42 T 11-10-2018 IPR000160 GGDEF domain TO73_1130 d7652df284fc67c5f9fe889a08664828 156 Gene3D G3DSA:1.10.287.180 2 76 1.8E-24 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TO73_1130 d7652df284fc67c5f9fe889a08664828 156 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 119 135 - T 11-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TO73_1130 d7652df284fc67c5f9fe889a08664828 156 Hamap MF_00105 Transcription elongation factor GreA [greA]. 3 154 26.619 T 11-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 TO73_1130 d7652df284fc67c5f9fe889a08664828 156 SUPERFAMILY SSF54534 82 154 4.84E-18 T 11-10-2018 TO73_1130 d7652df284fc67c5f9fe889a08664828 156 Pfam PF03449 Transcription elongation factor, N-terminal 5 75 5.7E-26 T 11-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TO73_1130 d7652df284fc67c5f9fe889a08664828 156 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 154 9.6E-25 T 11-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TO73_1130 d7652df284fc67c5f9fe889a08664828 156 Gene3D G3DSA:3.10.50.30 77 154 6.2E-22 T 11-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TO73_1130 d7652df284fc67c5f9fe889a08664828 156 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 6 154 5.5E-53 T 11-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 TO73_1130 d7652df284fc67c5f9fe889a08664828 156 SUPERFAMILY SSF46557 4 77 4.19E-22 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TO73_1130 d7652df284fc67c5f9fe889a08664828 156 PIRSF PIRSF006092 1 156 6.4E-55 T 11-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 458 519 1.1E-11 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 125 134 - T 11-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 SUPERFAMILY SSF53738 192 300 3.3E-13 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 303 420 4.4E-27 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 Gene3D G3DSA:3.40.120.10 204 301 1.5E-45 T 11-10-2018 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 SUPERFAMILY SSF53738 13 218 5.65E-46 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 SUPERFAMILY SSF53738 288 428 1.1E-31 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 194 300 5.4E-18 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 SUPERFAMILY SSF55957 415 523 1.44E-20 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 Gene3D G3DSA:3.40.120.10 4 203 1.5E-73 T 11-10-2018 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 Gene3D G3DSA:3.40.120.10 302 423 2.6E-35 T 11-10-2018 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 27 164 7.4E-34 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0040 fd5b15f6698dfe377649c06f6ab6138e 524 Gene3D G3DSA:3.30.310.50 424 524 1.5E-29 T 11-10-2018 TO73_2184 9164ba29a6b774a9be60c85b50fd1be8 136 Gene3D G3DSA:3.90.79.10 4 124 8.2E-12 T 11-10-2018 TO73_2184 9164ba29a6b774a9be60c85b50fd1be8 136 SUPERFAMILY SSF55811 4 120 1.76E-12 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 1.2E-97 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 1.2E-97 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 1.2E-97 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 1.2E-97 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 387 406 1.2E-97 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 1.2E-97 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 1.2E-97 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 361 383 1.2E-97 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 Pfam PF02073 Thermophilic metalloprotease (M29) 5 406 3.9E-153 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 Gene3D G3DSA:3.40.1830.10 1 177 9.8E-60 T 11-10-2018 IPR035097 Peptidase M29, N-terminal TO73_1052 8591ce673decd3a6390b93d8049c4e81 408 SUPERFAMILY SSF144052 4 408 8.24E-137 T 11-10-2018 TO73_0118 12622387e37cf761c89883ed0bf5b5da 494 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 491 4.7E-175 T 11-10-2018 IPR004482 Mg chelatase-related protein TO73_0118 12622387e37cf761c89883ed0bf5b5da 494 Pfam PF01078 Magnesium chelatase, subunit ChlI 188 392 2.6E-93 T 11-10-2018 IPR000523 Magnesium chelatase ChlI domain TO73_0118 12622387e37cf761c89883ed0bf5b5da 494 SUPERFAMILY SSF54211 7 169 4.93E-36 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0118 12622387e37cf761c89883ed0bf5b5da 494 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 399 491 6.4E-30 T 11-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain TO73_0118 12622387e37cf761c89883ed0bf5b5da 494 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 141 1.2E-41 T 11-10-2018 TO73_0118 12622387e37cf761c89883ed0bf5b5da 494 SMART SM00382 208 389 7.4E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0118 12622387e37cf761c89883ed0bf5b5da 494 Gene3D G3DSA:3.30.230.10 21 167 2.9E-10 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0118 12622387e37cf761c89883ed0bf5b5da 494 Gene3D G3DSA:3.40.50.300 169 494 1.8E-59 T 11-10-2018 TO73_0118 12622387e37cf761c89883ed0bf5b5da 494 SUPERFAMILY SSF52540 188 491 8.65E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0282 956bbcb560dae4af84edf39ed71536d4 404 Pfam PF00266 Aminotransferase class-V 20 389 1.5E-146 T 11-10-2018 IPR000192 Aminotransferase class V domain TO73_0282 956bbcb560dae4af84edf39ed71536d4 404 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 400 2.6E-171 T 11-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TO73_0282 956bbcb560dae4af84edf39ed71536d4 404 Gene3D G3DSA:3.40.640.10 31 290 3.2E-173 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_0282 956bbcb560dae4af84edf39ed71536d4 404 SUPERFAMILY SSF53383 1 400 1.07E-129 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_0282 956bbcb560dae4af84edf39ed71536d4 404 Gene3D G3DSA:3.90.1150.10 7 393 3.2E-173 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1846 565b3651393e21ce605cf73b6ccc0dba 187 Pfam PF05685 Putative restriction endonuclease 13 177 1.3E-29 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1846 565b3651393e21ce605cf73b6ccc0dba 187 Gene3D G3DSA:3.90.1570.10 2 184 3.2E-55 T 11-10-2018 TO73_1846 565b3651393e21ce605cf73b6ccc0dba 187 SUPERFAMILY SSF52980 3 184 2.9E-39 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_0329 358788517fb56ef46ea8b5ae5532f5ca 502 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 246 6.4E-7 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0329 358788517fb56ef46ea8b5ae5532f5ca 502 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 356 464 1.3E-10 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0329 358788517fb56ef46ea8b5ae5532f5ca 502 Gene3D G3DSA:1.10.3720.10 265 501 3.0E-35 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0329 358788517fb56ef46ea8b5ae5532f5ca 502 Gene3D G3DSA:1.10.3720.10 10 250 3.2E-40 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0329 358788517fb56ef46ea8b5ae5532f5ca 502 SUPERFAMILY SSF161098 9 248 1.02E-34 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0329 358788517fb56ef46ea8b5ae5532f5ca 502 SUPERFAMILY SSF161098 263 496 1.44E-38 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0959 ecddb32e9bd7e9e19f7f96f99221d08c 247 SMART SM00382 27 223 2.0E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0959 ecddb32e9bd7e9e19f7f96f99221d08c 247 SUPERFAMILY SSF52540 2 245 2.36E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0959 ecddb32e9bd7e9e19f7f96f99221d08c 247 Pfam PF00005 ABC transporter 19 174 9.5E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0959 ecddb32e9bd7e9e19f7f96f99221d08c 247 Gene3D G3DSA:3.40.50.300 2 247 9.2E-61 T 11-10-2018 TO73_0959 ecddb32e9bd7e9e19f7f96f99221d08c 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 245 2.0E-5 T 11-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TO73_1901 0aa5fff1a4fce52c5d8e43eb94f127b3 123 Gene3D G3DSA:2.30.130.30 5 104 8.0E-35 T 11-10-2018 TO73_1901 0aa5fff1a4fce52c5d8e43eb94f127b3 123 SUPERFAMILY SSF88697 4 113 5.63E-27 T 11-10-2018 IPR015947 PUA-like superfamily TO73_1901 0aa5fff1a4fce52c5d8e43eb94f127b3 123 SMART SM01022 8 102 1.1E-4 T 11-10-2018 IPR007374 ASCH domain TO73_1901 0aa5fff1a4fce52c5d8e43eb94f127b3 123 Pfam PF04266 ASCH domain 10 99 5.6E-9 T 11-10-2018 IPR007374 ASCH domain TO73_2720 cbe0ed9dabe60c6e258de3ddfa01b355 826 SUPERFAMILY SSF52540 391 733 2.35E-35 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2720 cbe0ed9dabe60c6e258de3ddfa01b355 826 Pfam PF01935 Domain of unknown function DUF87 434 585 4.4E-8 T 11-10-2018 IPR002789 Helicase HerA, central domain TO73_2720 cbe0ed9dabe60c6e258de3ddfa01b355 826 Gene3D G3DSA:1.10.8.730 488 628 4.1E-42 T 11-10-2018 TO73_2720 cbe0ed9dabe60c6e258de3ddfa01b355 826 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 1 187 1.7E-6 T 11-10-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase TO73_2720 cbe0ed9dabe60c6e258de3ddfa01b355 826 Gene3D G3DSA:3.40.50.300 416 748 4.1E-42 T 11-10-2018 TO73_0899 97c2cba228a3d99fd1a93e161dea3d65 69 Gene3D G3DSA:3.90.550.10 5 62 2.3E-15 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0899 97c2cba228a3d99fd1a93e161dea3d65 69 Pfam PF00483 Nucleotidyl transferase 8 52 2.0E-8 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TO73_0899 97c2cba228a3d99fd1a93e161dea3d65 69 SUPERFAMILY SSF53448 7 52 7.8E-15 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 SUPERFAMILY SSF56784 1 208 1.42E-43 T 11-10-2018 IPR036412 HAD-like superfamily TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 Gene3D G3DSA:1.10.150.720 18 94 7.1E-41 T 11-10-2018 TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 67 196 1.6E-20 T 11-10-2018 TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 192 2.7E-11 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 3.6E-13 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 3.6E-13 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 3.6E-13 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 3.6E-13 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 187 200 3.6E-13 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 Gene3D G3DSA:3.40.50.1000 5 207 7.1E-41 T 11-10-2018 IPR023214 HAD superfamily TO73_0452 d0a5b87250194ab319746fc74e68ce9f 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 196 3.3E-14 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_2835 211fca3342194f798edd0436b6ed2158 557 Pfam PF02867 Ribonucleotide reductase, barrel domain 83 205 4.8E-25 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_2835 211fca3342194f798edd0436b6ed2158 557 TIGRFAM TIGR02510 NrdE-prime: ribonucleoside-diphosphate reductase, alpha chain 5 557 4.2E-288 T 11-10-2018 IPR013350 Ribonucleotide reductase alpha chain TO73_2835 211fca3342194f798edd0436b6ed2158 557 PRINTS PR01183 Ribonucleotide reductase large chain signature 323 345 2.2E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_2835 211fca3342194f798edd0436b6ed2158 557 PRINTS PR01183 Ribonucleotide reductase large chain signature 351 374 2.2E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_2835 211fca3342194f798edd0436b6ed2158 557 PRINTS PR01183 Ribonucleotide reductase large chain signature 156 175 2.2E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_2835 211fca3342194f798edd0436b6ed2158 557 PRINTS PR01183 Ribonucleotide reductase large chain signature 387 414 2.2E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_2835 211fca3342194f798edd0436b6ed2158 557 SUPERFAMILY SSF51998 81 538 4.58E-112 T 11-10-2018 TO73_2835 211fca3342194f798edd0436b6ed2158 557 Gene3D G3DSA:3.20.70.20 206 544 1.8E-93 T 11-10-2018 TO73_2835 211fca3342194f798edd0436b6ed2158 557 Gene3D G3DSA:3.20.70.20 29 205 3.3E-37 T 11-10-2018 TO73_2835 211fca3342194f798edd0436b6ed2158 557 Pfam PF02867 Ribonucleotide reductase, barrel domain 386 534 2.6E-34 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_2835 211fca3342194f798edd0436b6ed2158 557 Pfam PF02867 Ribonucleotide reductase, barrel domain 209 368 4.7E-24 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_0430 382beb167eefee8d4bc69c8622a20cbf 396 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 390 1.5E-113 T 11-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 TO73_0430 382beb167eefee8d4bc69c8622a20cbf 396 SUPERFAMILY SSF102645 181 395 4.58E-73 T 11-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TO73_0430 382beb167eefee8d4bc69c8622a20cbf 396 SUPERFAMILY SSF52507 3 177 2.09E-48 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TO73_0430 382beb167eefee8d4bc69c8622a20cbf 396 Gene3D G3DSA:3.40.50.10300 182 395 1.6E-78 T 11-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TO73_0430 382beb167eefee8d4bc69c8622a20cbf 396 Pfam PF02441 Flavoprotein 3 175 4.3E-40 T 11-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TO73_0430 382beb167eefee8d4bc69c8622a20cbf 396 Gene3D G3DSA:3.40.50.1950 2 181 2.4E-46 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TO73_0430 382beb167eefee8d4bc69c8622a20cbf 396 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 365 9.1E-67 T 11-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TO73_1012 548deccb7737faf6f9483d855924154e 247 Gene3D G3DSA:3.30.950.10 113 229 2.6E-27 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TO73_1012 548deccb7737faf6f9483d855924154e 247 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 78 111 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TO73_1012 548deccb7737faf6f9483d855924154e 247 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 210 7.3E-39 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TO73_1012 548deccb7737faf6f9483d855924154e 247 Gene3D G3DSA:3.40.1010.10 3 112 4.8E-26 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TO73_1012 548deccb7737faf6f9483d855924154e 247 SUPERFAMILY SSF53790 1 246 5.76E-59 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TO73_1931 d3ca3d64adbbac32236ca09dce6eb24e 208 TIGRFAM TIGR00017 cmk: cytidylate kinase 3 205 1.8E-56 T 11-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TO73_1931 d3ca3d64adbbac32236ca09dce6eb24e 208 Pfam PF02224 Cytidylate kinase 5 207 6.9E-57 T 11-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TO73_1931 d3ca3d64adbbac32236ca09dce6eb24e 208 Hamap MF_00238 Cytidylate kinase [cmk]. 3 208 26.377 T 11-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TO73_1931 d3ca3d64adbbac32236ca09dce6eb24e 208 SUPERFAMILY SSF52540 4 207 1.89E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1931 d3ca3d64adbbac32236ca09dce6eb24e 208 Gene3D G3DSA:3.40.50.300 1 208 4.3E-71 T 11-10-2018 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 291.556 T 11-10-2018 IPR006297 Elongation factor 4 GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 SUPERFAMILY SSF52540 5 232 3.22E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 SUPERFAMILY SSF54980 297 376 3.27E-19 T 11-10-2018 IPR035647 EF-G domain III/V-like TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 SUPERFAMILY SSF54980 405 502 8.15E-25 T 11-10-2018 IPR035647 EF-G domain III/V-like TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 TIGRFAM TIGR01393 lepA: elongation factor 4 8 603 1.2E-297 T 11-10-2018 IPR006297 Elongation factor 4 GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Gene3D G3DSA:3.30.70.3380 374 487 1.7E-46 T 11-10-2018 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Gene3D G3DSA:2.40.30.10 191 291 2.2E-34 T 11-10-2018 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 181 1.5E-19 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Pfam PF06421 GTP-binding protein LepA C-terminus 496 602 6.8E-50 T 11-10-2018 IPR013842 GTP-binding protein LepA, C-terminal TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 PRINTS PR00315 GTP-binding elongation factor signature 54 62 5.7E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 PRINTS PR00315 GTP-binding elongation factor signature 79 89 5.7E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 PRINTS PR00315 GTP-binding elongation factor signature 95 106 5.7E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 PRINTS PR00315 GTP-binding elongation factor signature 11 24 5.7E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 PRINTS PR00315 GTP-binding elongation factor signature 131 140 5.7E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Pfam PF00679 Elongation factor G C-terminus 404 492 3.5E-22 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Pfam PF00009 Elongation factor Tu GTP binding domain 8 186 3.1E-54 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 SMART SM00838 404 495 8.4E-4 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Gene3D G3DSA:3.40.50.300 5 190 2.7E-79 T 11-10-2018 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Pfam PF03144 Elongation factor Tu domain 2 210 281 7.8E-10 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Gene3D G3DSA:3.30.70.870 292 373 9.4E-36 T 11-10-2018 TO73_0684 7fa5be91ed31064d0be8d570d0e4d17a 610 Gene3D G3DSA:3.30.70.2570 488 562 2.4E-34 T 11-10-2018 IPR038363 LepA, C-terminal domain superfamily TO73_0275 63d4d486cce008674d5d9f66d3d602de 183 Pfam PF00156 Phosphoribosyl transferase domain 33 150 4.0E-11 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TO73_0275 63d4d486cce008674d5d9f66d3d602de 183 Gene3D G3DSA:3.40.50.2020 1 182 2.9E-50 T 11-10-2018 TO73_0275 63d4d486cce008674d5d9f66d3d602de 183 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 183 22.639 T 11-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_0275 63d4d486cce008674d5d9f66d3d602de 183 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 3 182 4.7E-63 T 11-10-2018 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_0275 63d4d486cce008674d5d9f66d3d602de 183 SUPERFAMILY SSF53271 3 177 8.8E-31 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_1277 122f57a78dc4b723d76be650dcc26b0d 280 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 38 274 1.9E-27 T 11-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TO73_1277 122f57a78dc4b723d76be650dcc26b0d 280 SUPERFAMILY SSF51735 11 277 2.07E-52 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1277 122f57a78dc4b723d76be650dcc26b0d 280 Gene3D G3DSA:3.30.1780.10 25 274 2.9E-51 T 11-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 TO73_1277 122f57a78dc4b723d76be650dcc26b0d 280 Gene3D G3DSA:3.40.50.720 106 264 2.9E-51 T 11-10-2018 TO73_2286 93a2a83d9c340fa79df6b19c3bf24319 302 Pfam PF00480 ROK family 4 292 3.3E-70 T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TO73_2286 93a2a83d9c340fa79df6b19c3bf24319 302 SUPERFAMILY SSF53067 1 296 2.22E-65 T 11-10-2018 TO73_2286 93a2a83d9c340fa79df6b19c3bf24319 302 Gene3D G3DSA:3.30.420.40 124 277 2.3E-114 T 11-10-2018 TO73_2286 93a2a83d9c340fa79df6b19c3bf24319 302 Gene3D G3DSA:3.30.420.40 4 290 2.3E-114 T 11-10-2018 TO73_2286 93a2a83d9c340fa79df6b19c3bf24319 302 ProSitePatterns PS01125 ROK family signature. 132 159 - T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TO73_2132 2623ac3b1ff3feb513f20642a7fe2bc0 607 Gene3D G3DSA:3.60.9.10 2 209 6.8E-82 T 11-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TO73_2132 2623ac3b1ff3feb513f20642a7fe2bc0 607 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 204 4.3E-76 T 11-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_2132 2623ac3b1ff3feb513f20642a7fe2bc0 607 SMART SM00790 5 206 3.3E-123 T 11-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_2132 2623ac3b1ff3feb513f20642a7fe2bc0 607 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 238 601 1.7E-120 T 11-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_2132 2623ac3b1ff3feb513f20642a7fe2bc0 607 SUPERFAMILY SSF48310 213 601 1.7E-121 T 11-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_2132 2623ac3b1ff3feb513f20642a7fe2bc0 607 Gene3D G3DSA:1.10.569.10 247 430 3.0E-121 T 11-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TO73_2132 2623ac3b1ff3feb513f20642a7fe2bc0 607 Gene3D G3DSA:1.10.599.10 246 601 3.0E-121 T 11-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TO73_2132 2623ac3b1ff3feb513f20642a7fe2bc0 607 SUPERFAMILY SSF56228 3 207 3.14E-75 T 11-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TO73_2400 11f146aab0379b225084f1a432d19d09 193 SMART SM00028 56 89 14.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_2400 11f146aab0379b225084f1a432d19d09 193 SMART SM00028 90 123 3.4E-7 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_2400 11f146aab0379b225084f1a432d19d09 193 SMART SM00028 124 157 83.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_2400 11f146aab0379b225084f1a432d19d09 193 Pfam PF13414 TPR repeat 97 138 5.8E-13 T 11-10-2018 TO73_2400 11f146aab0379b225084f1a432d19d09 193 Gene3D G3DSA:1.25.40.10 60 165 6.1E-25 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2400 11f146aab0379b225084f1a432d19d09 193 SUPERFAMILY SSF48452 49 153 1.38E-22 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2071 3679835cd7469db172d4a153e7fc76ff 112 SUPERFAMILY SSF52980 5 104 6.65E-17 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_2071 3679835cd7469db172d4a153e7fc76ff 112 Pfam PF02021 Uncharacterised protein family UPF0102 9 96 2.1E-20 T 11-10-2018 IPR003509 Uncharacterised protein family UPF0102 TO73_2071 3679835cd7469db172d4a153e7fc76ff 112 Gene3D G3DSA:3.40.1350.10 8 109 1.1E-20 T 11-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TO73_2071 3679835cd7469db172d4a153e7fc76ff 112 Hamap MF_00048 UPF0102 protein YraN [yraN]. 2 109 18.969 T 11-10-2018 IPR003509 Uncharacterised protein family UPF0102 TO73_2328 989e3c08a70b36ed70e6a82babcd6152 137 Pfam PF01934 Protein of unknown function DUF86 15 131 9.0E-28 T 11-10-2018 IPR008201 Protein of unknown function DUF86 TO73_2328 989e3c08a70b36ed70e6a82babcd6152 137 SUPERFAMILY SSF81593 5 113 9.42E-6 T 11-10-2018 TO73_2328 989e3c08a70b36ed70e6a82babcd6152 137 Gene3D G3DSA:1.20.120.580 4 137 1.6E-15 T 11-10-2018 IPR037038 Bsu32300-like superfamily TO73_0993 ebeeba05c5c9241be202132639c97c1f 153 PIRSF PIRSF014972 1 136 1.3E-36 T 11-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase TO73_0993 ebeeba05c5c9241be202132639c97c1f 153 SUPERFAMILY SSF54637 2 135 4.04E-36 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_0993 ebeeba05c5c9241be202132639c97c1f 153 Gene3D G3DSA:3.10.129.10 1 141 2.4E-36 T 11-10-2018 TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 Pfam PF00226 DnaJ domain 3 64 4.1E-29 T 11-10-2018 IPR001623 DnaJ domain TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 Gene3D G3DSA:2.60.260.20 111 175 8.0E-25 T 11-10-2018 TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 SUPERFAMILY SSF49493 108 183 1.57E-16 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 Gene3D G3DSA:1.10.287.110 1 110 4.8E-47 T 11-10-2018 IPR036869 Chaperone J-domain superfamily TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 SUPERFAMILY SSF46565 1 102 2.22E-35 T 11-10-2018 IPR036869 Chaperone J-domain superfamily TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 SMART SM00271 2 59 1.5E-33 T 11-10-2018 IPR001623 DnaJ domain TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 ProSitePatterns PS00636 Nt-dnaJ domain signature. 44 63 - T 11-10-2018 IPR018253 DnaJ domain, conserved site TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 Pfam PF01556 DnaJ C terminal domain 116 254 4.7E-31 T 11-10-2018 IPR002939 Chaperone DnaJ, C-terminal TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 SUPERFAMILY SSF49493 181 265 3.4E-18 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 PRINTS PR00625 DnaJ domain signature 39 59 1.6E-26 T 11-10-2018 IPR001623 DnaJ domain TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 PRINTS PR00625 DnaJ domain signature 5 23 1.6E-26 T 11-10-2018 IPR001623 DnaJ domain TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 PRINTS PR00625 DnaJ domain signature 23 38 1.6E-26 T 11-10-2018 IPR001623 DnaJ domain TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 PRINTS PR00625 DnaJ domain signature 59 78 1.6E-26 T 11-10-2018 IPR001623 DnaJ domain TO73_1921 94196b514bf52e9c9da1f40d035c2cb9 276 Gene3D G3DSA:2.60.260.20 177 276 4.2E-31 T 11-10-2018 TO73_1484 baa78d2880f0996bf2d55150d42ab160 299 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 62 291 1.0E-37 T 11-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 TO73_1484 baa78d2880f0996bf2d55150d42ab160 299 Gene3D G3DSA:1.10.8.60 107 168 8.5E-7 T 11-10-2018 TO73_1484 baa78d2880f0996bf2d55150d42ab160 299 SUPERFAMILY SSF48019 172 292 2.38E-24 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TO73_1484 baa78d2880f0996bf2d55150d42ab160 299 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 174 292 6.0E-6 T 11-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 TO73_1484 baa78d2880f0996bf2d55150d42ab160 299 Gene3D G3DSA:1.20.272.10 172 296 2.0E-29 T 11-10-2018 TO73_1484 baa78d2880f0996bf2d55150d42ab160 299 SUPERFAMILY SSF52540 43 165 2.5E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1185 b25128f6f1f4f35792cc849e57eab380 425 Pfam PF03237 Terminase-like family 23 222 1.1E-16 T 11-10-2018 IPR004921 Terminase large subunit, T4likevirus-type TO73_1185 b25128f6f1f4f35792cc849e57eab380 425 Pfam PF17289 Terminase RNaseH-like domain 249 400 1.8E-18 T 11-10-2018 IPR035421 Terminase, large subunit gp17-like TO73_1185 b25128f6f1f4f35792cc849e57eab380 425 Gene3D G3DSA:3.30.420.240 222 402 8.1E-30 T 11-10-2018 TO73_1185 b25128f6f1f4f35792cc849e57eab380 425 Gene3D G3DSA:3.40.50.300 1 177 1.7E-42 T 11-10-2018 TO73_0656 400a90f406be70ca0c6ab7b662cbd497 253 SMART SM00382 28 236 9.8E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0656 400a90f406be70ca0c6ab7b662cbd497 253 Pfam PF00005 ABC transporter 19 180 5.4E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0656 400a90f406be70ca0c6ab7b662cbd497 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 2.8E-9 T 11-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TO73_0656 400a90f406be70ca0c6ab7b662cbd497 253 Gene3D G3DSA:3.40.50.300 2 251 1.4E-63 T 11-10-2018 TO73_0656 400a90f406be70ca0c6ab7b662cbd497 253 SUPERFAMILY SSF52540 4 249 1.2E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0110 a37c10e4deebc04f2601ee5a8c20c442 401 Pfam PF09670 CRISPR-associated protein (Cas_Cas02710) 13 391 1.7E-116 T 11-10-2018 TO73_0110 a37c10e4deebc04f2601ee5a8c20c442 401 SUPERFAMILY SSF52980 1 120 8.04E-5 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_0110 a37c10e4deebc04f2601ee5a8c20c442 401 TIGRFAM TIGR02710 TIGR02710: CRISPR-associated protein, TIGR02710 family 13 391 2.9E-142 T 11-10-2018 IPR014082 CRISPR-associated protein, Cas02710 TO73_1129 809164e2351f9018b6d3c9d55a8c7655 221 SUPERFAMILY SSF57863 84 148 2.09E-5 T 11-10-2018 IPR037278 ARFGAP/RecO-like zinc finger TO73_1129 809164e2351f9018b6d3c9d55a8c7655 221 Gene3D G3DSA:2.40.50.140 1 83 1.3E-24 T 11-10-2018 TO73_1129 809164e2351f9018b6d3c9d55a8c7655 221 Pfam PF11967 Recombination protein O N terminal 7 77 3.3E-11 T 11-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal TO73_1129 809164e2351f9018b6d3c9d55a8c7655 221 SUPERFAMILY SSF50249 3 77 7.37E-11 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1129 809164e2351f9018b6d3c9d55a8c7655 221 Gene3D G3DSA:1.20.1440.120 84 151 2.2E-5 T 11-10-2018 TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 993 3.1E-43 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 SMART SM00968 444 560 5.7E-27 T 11-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 PIRSF PIRSF005719 4 308 1.8E-63 T 11-10-2018 IPR024704 Structural maintenance of chromosomes protein TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 PIRSF PIRSF005719 661 1006 1.5E-46 T 11-10-2018 IPR024704 Structural maintenance of chromosomes protein TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 PIRSF PIRSF005719 322 645 3.8E-39 T 11-10-2018 IPR024704 Structural maintenance of chromosomes protein TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 Gene3D G3DSA:3.30.70.1620 503 588 3.8E-34 T 11-10-2018 TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 SUPERFAMILY SSF75553 411 606 3.01E-31 T 11-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 Gene3D G3DSA:3.40.50.300 4 230 1.7E-35 T 11-10-2018 TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 Gene3D G3DSA:3.40.50.300 770 1006 3.4E-28 T 11-10-2018 TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 Gene3D G3DSA:1.20.1060.20 441 598 3.8E-34 T 11-10-2018 TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 Pfam PF06470 SMC proteins Flexible Hinge Domain 444 559 1.1E-18 T 11-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TO73_1108 66fa6ed3735a7e6b479dad1d251b0cfe 1007 SUPERFAMILY SSF52540 4 994 8.18E-41 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 SUPERFAMILY SSF53850 2 206 1.19E-72 T 11-10-2018 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 220 289 9.8E-18 T 11-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 291 8.8E-100 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 224 240 - T 11-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 203 1.2E-70 T 11-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 Gene3D G3DSA:3.30.160.40 214 299 2.2E-23 T 11-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 SUPERFAMILY SSF54782 213 298 7.19E-22 T 11-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 291 35.842 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 PIRSF PIRSF001438 1 302 2.5E-109 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 PRINTS PR00151 Porphobilinogen deaminase signature 117 134 1.1E-30 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 PRINTS PR00151 Porphobilinogen deaminase signature 69 88 1.1E-30 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 PRINTS PR00151 Porphobilinogen deaminase signature 136 153 1.1E-30 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 PRINTS PR00151 Porphobilinogen deaminase signature 223 240 1.1E-30 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 Gene3D G3DSA:3.40.190.10 93 192 8.9E-81 T 11-10-2018 TO73_2199 9594096fbb12da9c494bd3d8ccdb2d6a 303 Gene3D G3DSA:3.40.190.10 5 207 8.9E-81 T 11-10-2018 TO73_1287 0d78fd46ea4dda855318063f448dd446 665 Pfam PF02272 DHHA1 domain 303 415 2.2E-8 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TO73_1287 0d78fd46ea4dda855318063f448dd446 665 Pfam PF01368 DHH family 74 172 1.0E-9 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TO73_1287 0d78fd46ea4dda855318063f448dd446 665 Gene3D G3DSA:3.90.1640.30 46 306 2.3E-248 T 11-10-2018 TO73_1287 0d78fd46ea4dda855318063f448dd446 665 Gene3D G3DSA:1.20.120.1040 535 665 2.4E-59 T 11-10-2018 TO73_1287 0d78fd46ea4dda855318063f448dd446 665 SUPERFAMILY SSF64182 52 427 4.58E-105 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily TO73_1287 0d78fd46ea4dda855318063f448dd446 665 Gene3D G3DSA:3.10.310.30 307 422 2.3E-248 T 11-10-2018 TO73_1287 0d78fd46ea4dda855318063f448dd446 665 Gene3D G3DSA:2.40.50.460 2 534 2.3E-248 T 11-10-2018 TO73_0056 be77e719de8b6059e3c32b1758508d42 469 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 1 467 37.417 T 11-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TO73_0056 be77e719de8b6059e3c32b1758508d42 469 SMART SM00845 319 466 5.6E-51 T 11-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TO73_0056 be77e719de8b6059e3c32b1758508d42 469 Gene3D G3DSA:1.10.150.380 289 393 3.3E-26 T 11-10-2018 TO73_0056 be77e719de8b6059e3c32b1758508d42 469 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 466 1.6E-155 T 11-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TO73_0056 be77e719de8b6059e3c32b1758508d42 469 SUPERFAMILY SSF89095 289 392 1.22E-20 T 11-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TO73_0056 be77e719de8b6059e3c32b1758508d42 469 SUPERFAMILY SSF55931 3 288 9.16E-110 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TO73_0056 be77e719de8b6059e3c32b1758508d42 469 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 137 151 - T 11-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TO73_0056 be77e719de8b6059e3c32b1758508d42 469 Gene3D G3DSA:1.10.10.410 406 467 3.8E-17 T 11-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TO73_0056 be77e719de8b6059e3c32b1758508d42 469 Pfam PF02637 GatB domain 322 466 2.1E-40 T 11-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TO73_0056 be77e719de8b6059e3c32b1758508d42 469 Pfam PF02934 GatB/GatE catalytic domain 4 280 4.8E-106 T 11-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 Pfam PF07729 FCD domain 84 204 9.8E-26 T 11-10-2018 IPR011711 GntR, C-terminal TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 SMART SM00345 16 74 6.2E-20 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 Gene3D G3DSA:1.10.10.10 10 73 4.0E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 SMART SM00895 84 206 1.2E-23 T 11-10-2018 IPR011711 GntR, C-terminal TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 Gene3D G3DSA:1.20.120.530 74 214 4.4E-31 T 11-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 5.2E-20 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-6 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-6 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 SUPERFAMILY SSF46785 6 78 2.29E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_2032 d433e8c03ec9cb598ed43fa3c98285cd 219 SUPERFAMILY SSF48008 79 213 1.91E-27 T 11-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TO73_0342 d1865c2b7825ac92d47022fc6c460def 398 SUPERFAMILY SSF103473 13 384 3.01E-20 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_0342 d1865c2b7825ac92d47022fc6c460def 398 Gene3D G3DSA:1.20.1250.20 9 377 3.4E-19 T 11-10-2018 TO73_0342 d1865c2b7825ac92d47022fc6c460def 398 Pfam PF07690 Major Facilitator Superfamily 15 261 4.2E-9 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_2112 ec199f1f729ea24993b745bc0884cb9b 233 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 12 232 6.6E-79 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TO73_2112 ec199f1f729ea24993b745bc0884cb9b 233 Pfam PF01209 ubiE/COQ5 methyltransferase family 8 231 6.2E-65 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TO73_2112 ec199f1f729ea24993b745bc0884cb9b 233 SUPERFAMILY SSF53335 6 219 1.34E-51 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2112 ec199f1f729ea24993b745bc0884cb9b 233 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 23 38 - T 11-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TO73_2112 ec199f1f729ea24993b745bc0884cb9b 233 Gene3D G3DSA:3.40.50.150 18 232 3.5E-66 T 11-10-2018 TO73_2112 ec199f1f729ea24993b745bc0884cb9b 233 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 3 233 36.742 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TO73_2211 a30ab834f56c9f6ed8bac1a054bac7e6 270 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 24 270 1.1E-116 T 11-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 TO73_2211 a30ab834f56c9f6ed8bac1a054bac7e6 270 Gene3D G3DSA:3.40.50.300 21 268 8.0E-71 T 11-10-2018 TO73_2211 a30ab834f56c9f6ed8bac1a054bac7e6 270 Pfam PF00005 ABC transporter 41 195 4.8E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_2211 a30ab834f56c9f6ed8bac1a054bac7e6 270 SMART SM00382 48 246 2.3E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2211 a30ab834f56c9f6ed8bac1a054bac7e6 270 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_2211 a30ab834f56c9f6ed8bac1a054bac7e6 270 SUPERFAMILY SSF52540 23 264 2.97E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2082 6e80444f70d4e37363ea7568877e3f2b 258 Pfam PF01676 Metalloenzyme superfamily 152 228 5.2E-8 T 11-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TO73_2082 6e80444f70d4e37363ea7568877e3f2b 258 Gene3D G3DSA:3.40.720.10 145 240 2.5E-6 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TO73_2082 6e80444f70d4e37363ea7568877e3f2b 258 SUPERFAMILY SSF53649 1 231 4.25E-14 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TO73_0399 cd65ded905bbdb7171d12524bb10f4e8 72 Pfam PF01176 Translation initiation factor 1A / IF-1 10 71 5.5E-27 T 11-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TO73_0399 cd65ded905bbdb7171d12524bb10f4e8 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 24.32 T 11-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TO73_0399 cd65ded905bbdb7171d12524bb10f4e8 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 6 72 1.5E-33 T 11-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TO73_0399 cd65ded905bbdb7171d12524bb10f4e8 72 SUPERFAMILY SSF50249 4 71 1.69E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0399 cd65ded905bbdb7171d12524bb10f4e8 72 Gene3D G3DSA:2.40.50.140 2 72 3.9E-37 T 11-10-2018 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 SMART SM00382 192 335 1.5E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 SMART SM00382 476 642 1.2E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 641 711 3.3E-13 T 11-10-2018 IPR019489 Clp ATPase, C-terminal TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 SMART SM01086 641 726 2.3E-17 T 11-10-2018 IPR019489 Clp ATPase, C-terminal TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 554 572 6.3E-36 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 525 543 6.3E-36 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 480 498 6.3E-36 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 587 601 6.3E-36 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 286 298 - T 11-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Pfam PF07724 AAA domain (Cdc48 subfamily) 478 635 2.7E-45 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Gene3D G3DSA:1.10.8.60 334 430 3.8E-26 T 11-10-2018 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Gene3D G3DSA:3.40.50.300 145 333 6.5E-71 T 11-10-2018 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Gene3D G3DSA:1.10.1780.10 1 144 1.1E-41 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 SUPERFAMILY SSF52540 434 705 2.8E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Gene3D G3DSA:1.10.8.60 641 731 9.4E-12 T 11-10-2018 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 480 493 - T 11-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 197 330 5.1E-14 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Gene3D G3DSA:3.40.50.300 431 639 2.2E-76 T 11-10-2018 TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 SUPERFAMILY SSF52540 153 398 7.04E-68 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 15 66 2.7E-13 T 11-10-2018 IPR004176 Clp, N-terminal TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 90 140 1.1E-12 T 11-10-2018 IPR004176 Clp, N-terminal TO73_1363 2cdf1f21b2e07cb367d01080f2b30caf 734 SUPERFAMILY SSF81923 2 145 2.49E-23 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TO73_0669 c5373016414232565de6dc77ba4f37d9 387 Pfam PF01609 Transposase DDE domain 160 315 1.3E-14 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_0669 c5373016414232565de6dc77ba4f37d9 387 Gene3D G3DSA:3.90.350.10 58 306 4.5E-26 T 11-10-2018 IPR014736 Transposase, Tn5-like, core TO73_0669 c5373016414232565de6dc77ba4f37d9 387 SUPERFAMILY SSF53098 2 377 5.39E-47 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 Gene3D G3DSA:3.90.190.20 300 445 1.8E-42 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 Pfam PF02875 Mur ligase family, glutamate ligase domain 302 383 1.8E-15 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 SUPERFAMILY SSF51984 1 85 8.63E-19 T 11-10-2018 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 Pfam PF08245 Mur ligase middle domain 103 282 8.0E-15 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 Gene3D G3DSA:3.40.50.720 2 86 3.2E-21 T 11-10-2018 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 SUPERFAMILY SSF53244 301 443 6.41E-34 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 Gene3D G3DSA:3.40.1190.10 87 299 6.1E-50 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 Pfam PF01225 Mur ligase family, catalytic domain 4 98 7.0E-19 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 SUPERFAMILY SSF53623 84 299 2.09E-45 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 442 8.5E-105 T 11-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1230 ea93c50180fd2abb2d9261ec39d52af8 446 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 446 30.975 T 11-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1245 14877e99c5d4c39335a36683039dda34 287 Gene3D G3DSA:3.40.50.720 2 253 8.4E-51 T 11-10-2018 TO73_1245 14877e99c5d4c39335a36683039dda34 287 Pfam PF13460 NAD(P)H-binding 7 140 3.5E-19 T 11-10-2018 IPR016040 NAD(P)-binding domain TO73_1245 14877e99c5d4c39335a36683039dda34 287 SUPERFAMILY SSF51735 1 248 3.82E-55 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0703 d62c5976102ff4da4ace93d001a42e5f 156 SUPERFAMILY SSF54534 81 154 1.83E-16 T 11-10-2018 TO73_0703 d62c5976102ff4da4ace93d001a42e5f 156 SUPERFAMILY SSF46557 4 76 2.22E-13 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TO73_0703 d62c5976102ff4da4ace93d001a42e5f 156 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 155 2.5E-20 T 11-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TO73_0703 d62c5976102ff4da4ace93d001a42e5f 156 PIRSF PIRSF006092 1 156 1.7E-47 T 11-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TO73_0703 d62c5976102ff4da4ace93d001a42e5f 156 Gene3D G3DSA:3.10.50.30 78 151 5.5E-28 T 11-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TO73_0703 d62c5976102ff4da4ace93d001a42e5f 156 Gene3D G3DSA:1.10.287.180 1 77 5.2E-32 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TO73_0703 d62c5976102ff4da4ace93d001a42e5f 156 Pfam PF03449 Transcription elongation factor, N-terminal 6 74 4.1E-16 T 11-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TO73_0703 d62c5976102ff4da4ace93d001a42e5f 156 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 11-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TO73_2872 56d531b393910704052e181d302cfbdd 318 Pfam PF00589 Phage integrase family 149 312 3.9E-5 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TO73_2872 56d531b393910704052e181d302cfbdd 318 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 57 126 1.7E-5 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TO73_2872 56d531b393910704052e181d302cfbdd 318 SUPERFAMILY SSF56349 149 309 7.06E-15 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TO73_2872 56d531b393910704052e181d302cfbdd 318 Gene3D G3DSA:1.10.443.10 141 315 9.2E-9 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TO73_0375 a884c18a300c29039dacf362a50292a6 105 SUPERFAMILY SSF54999 3 99 3.01E-35 T 11-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TO73_0375 a884c18a300c29039dacf362a50292a6 105 Pfam PF00338 Ribosomal protein S10p/S20e 5 99 1.5E-33 T 11-10-2018 IPR027486 Ribosomal protein S10 domain TO73_0375 a884c18a300c29039dacf362a50292a6 105 SMART SM01403 5 99 1.4E-52 T 11-10-2018 IPR027486 Ribosomal protein S10 domain TO73_0375 a884c18a300c29039dacf362a50292a6 105 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 26.007 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0375 a884c18a300c29039dacf362a50292a6 105 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 3 99 2.3E-43 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0375 a884c18a300c29039dacf362a50292a6 105 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 11-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0375 a884c18a300c29039dacf362a50292a6 105 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 5.3E-19 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0375 a884c18a300c29039dacf362a50292a6 105 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 5.3E-19 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0375 a884c18a300c29039dacf362a50292a6 105 PRINTS PR00971 Ribosomal protein S10 family signature 59 73 5.3E-19 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0375 a884c18a300c29039dacf362a50292a6 105 Gene3D G3DSA:3.30.70.600 1 105 1.2E-38 T 11-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TO73_0739 4d396debb1165fe9c7465f57380c8f5a 170 Gene3D G3DSA:2.60.40.420 58 169 1.4E-29 T 11-10-2018 IPR008972 Cupredoxin TO73_0739 4d396debb1165fe9c7465f57380c8f5a 170 Gene3D G3DSA:1.20.1070.10 3 48 2.7E-11 T 11-10-2018 TO73_0739 4d396debb1165fe9c7465f57380c8f5a 170 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 114 162 - T 11-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0739 4d396debb1165fe9c7465f57380c8f5a 170 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 95 168 6.8E-10 T 11-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0739 4d396debb1165fe9c7465f57380c8f5a 170 Pfam PF09125 Cytochrome C oxidase subunit II, transmembrane 9 41 6.6E-10 T 11-10-2018 IPR015209 Cytochrome C oxidase subunit IIa, transmembrane domain KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TO73_0739 4d396debb1165fe9c7465f57380c8f5a 170 SUPERFAMILY SSF81464 6 41 4.84E-8 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0739 4d396debb1165fe9c7465f57380c8f5a 170 SUPERFAMILY SSF49503 45 169 2.38E-33 T 11-10-2018 IPR008972 Cupredoxin TO73_0350 e44ccc48df33cbb80bc61e0cb3063c0f 767 Gene3D G3DSA:3.60.20.10 251 747 2.2E-172 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_0350 e44ccc48df33cbb80bc61e0cb3063c0f 767 Gene3D G3DSA:1.10.439.10 21 182 4.3E-61 T 11-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 TO73_0350 e44ccc48df33cbb80bc61e0cb3063c0f 767 Pfam PF01804 Penicillin amidase 49 755 1.3E-229 T 11-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 TO73_0350 e44ccc48df33cbb80bc61e0cb3063c0f 767 Gene3D G3DSA:2.30.120.10 323 390 2.2E-172 T 11-10-2018 TO73_0350 e44ccc48df33cbb80bc61e0cb3063c0f 767 SUPERFAMILY SSF56235 45 756 2.83E-225 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_0350 e44ccc48df33cbb80bc61e0cb3063c0f 767 Gene3D G3DSA:1.10.1400.10 540 659 2.2E-172 T 11-10-2018 TO73_0350 e44ccc48df33cbb80bc61e0cb3063c0f 767 PIRSF PIRSF001227 8 759 2.4E-196 T 11-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 SUPERFAMILY SSF50129 8 100 1.65E-35 T 11-10-2018 IPR011032 GroES-like superfamily TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 PRINTS PR00297 10kDa chaperonin signature 31 52 6.6E-33 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 PRINTS PR00297 10kDa chaperonin signature 87 100 6.6E-33 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 PRINTS PR00297 10kDa chaperonin signature 9 24 6.6E-33 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 PRINTS PR00297 10kDa chaperonin signature 66 78 6.6E-33 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 Gene3D G3DSA:2.30.33.40 8 101 4.4E-40 T 11-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 ProSitePatterns PS00681 Chaperonins cpn10 signature. 9 33 - T 11-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 SMART SM00883 8 100 4.1E-55 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 Pfam PF00166 Chaperonin 10 Kd subunit 9 99 7.6E-37 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TO73_0030 6e6b2531ae4c1c26d8c93f021c2ae69f 101 Hamap MF_00580 10 kDa chaperonin [groS]. 8 101 27.956 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TO73_0807 d8f906b3a0bffcf3819d4cb9c0834bca 237 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 29 43 2.5E-22 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TO73_0807 d8f906b3a0bffcf3819d4cb9c0834bca 237 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 202 222 2.5E-22 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TO73_0807 d8f906b3a0bffcf3819d4cb9c0834bca 237 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 160 177 2.5E-22 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TO73_0807 d8f906b3a0bffcf3819d4cb9c0834bca 237 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 179 197 2.5E-22 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TO73_0807 d8f906b3a0bffcf3819d4cb9c0834bca 237 SUPERFAMILY SSF53335 6 222 5.28E-35 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_0807 d8f906b3a0bffcf3819d4cb9c0834bca 237 Gene3D G3DSA:3.40.50.150 11 136 1.3E-9 T 11-10-2018 TO73_0807 d8f906b3a0bffcf3819d4cb9c0834bca 237 Gene3D G3DSA:3.40.50.150 137 230 1.6E-21 T 11-10-2018 TO73_0807 d8f906b3a0bffcf3819d4cb9c0834bca 237 Pfam PF01555 DNA methylase 157 218 9.8E-16 T 11-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 TO73_0807 d8f906b3a0bffcf3819d4cb9c0834bca 237 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 33 39 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TO73_2823 805e51b7653ff2a66b7ce2c65b431559 210 SUPERFAMILY SSF47240 42 170 7.15E-17 T 11-10-2018 IPR009078 Ferritin-like superfamily TO73_2823 805e51b7653ff2a66b7ce2c65b431559 210 Pfam PF13668 Ferritin-like domain 43 170 8.8E-33 T 11-10-2018 TO73_1723 ed2794fcc975200bb947ddc70c0d544b 186 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 98 1.4E-25 T 11-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 TO73_1723 ed2794fcc975200bb947ddc70c0d544b 186 Gene3D G3DSA:3.30.160.100 1 105 2.8E-39 T 11-10-2018 IPR036567 Ribosome hibernation promotion factor-like TO73_1723 ed2794fcc975200bb947ddc70c0d544b 186 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 127 182 8.9E-32 T 11-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal TO73_1723 ed2794fcc975200bb947ddc70c0d544b 186 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 186 24.579 T 11-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid TO73_1723 ed2794fcc975200bb947ddc70c0d544b 186 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 5 98 7.6E-24 T 11-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 TO73_1723 ed2794fcc975200bb947ddc70c0d544b 186 SUPERFAMILY SSF69754 5 106 2.09E-27 T 11-10-2018 IPR036567 Ribosome hibernation promotion factor-like TO73_1723 ed2794fcc975200bb947ddc70c0d544b 186 Gene3D G3DSA:3.30.505.50 140 186 7.0E-28 T 11-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily TO73_1433 529c8bdc7e18dc31e2fda541c2c738a7 550 Gene3D G3DSA:3.50.30.80 357 506 4.2E-53 T 11-10-2018 TO73_1433 529c8bdc7e18dc31e2fda541c2c738a7 550 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 535 41.715 T 11-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TO73_1433 529c8bdc7e18dc31e2fda541c2c738a7 550 SUPERFAMILY SSF52016 357 535 4.55E-60 T 11-10-2018 TO73_1433 529c8bdc7e18dc31e2fda541c2c738a7 550 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 443 454 - T 11-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TO73_1433 529c8bdc7e18dc31e2fda541c2c738a7 550 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 102 112 - T 11-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TO73_1433 529c8bdc7e18dc31e2fda541c2c738a7 550 SUPERFAMILY SSF143975 1 356 3.4E-119 T 11-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TO73_1433 529c8bdc7e18dc31e2fda541c2c738a7 550 Pfam PF00920 Dehydratase family 14 532 6.3E-197 T 11-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TO73_1433 529c8bdc7e18dc31e2fda541c2c738a7 550 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 1 535 5.9E-201 T 11-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TO73_0333 e9744e3d01fc7b37555067269f6b57a1 80 SUPERFAMILY SSF55248 2 78 2.09E-28 T 11-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TO73_0333 e9744e3d01fc7b37555067269f6b57a1 80 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 2 76 2.6E-26 T 11-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TO73_0333 e9744e3d01fc7b37555067269f6b57a1 80 Gene3D G3DSA:3.30.1360.20 1 79 1.9E-32 T 11-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 Gene3D G3DSA:1.25.40.10 139 258 1.8E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 257 323 6.7E-12 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 SUPERFAMILY SSF48452 136 240 6.33E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 Pfam PF13432 Tetratricopeptide repeat 141 199 1.4E-7 T 11-10-2018 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 Pfam PF07719 Tetratricopeptide repeat 205 233 1.3E-5 T 11-10-2018 IPR013105 Tetratricopeptide repeat 2 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 SMART SM00028 137 170 3.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 SMART SM00028 171 204 160.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 SMART SM00028 205 238 0.0047 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 SUPERFAMILY SSF46626 210 326 3.55E-19 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0531 1dba2e9f66ebce2fc5acae57f13cd38d 326 Gene3D G3DSA:1.10.760.10 259 326 1.1E-15 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_1228 f7e07b6fdbfe872fd3757b86fb244b09 352 Pfam PF01098 Cell cycle protein 32 341 8.8E-62 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_2284 d1eb6c9cfb3edf4a4acb80ee778fb26b 356 Gene3D G3DSA:3.30.70.360 159 273 1.0E-74 T 11-10-2018 TO73_2284 d1eb6c9cfb3edf4a4acb80ee778fb26b 356 Gene3D G3DSA:3.40.630.10 16 341 1.0E-74 T 11-10-2018 TO73_2284 d1eb6c9cfb3edf4a4acb80ee778fb26b 356 SUPERFAMILY SSF53187 3 354 1.31E-49 T 11-10-2018 TO73_2284 d1eb6c9cfb3edf4a4acb80ee778fb26b 356 SUPERFAMILY SSF55031 163 252 4.49E-11 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TO73_2284 d1eb6c9cfb3edf4a4acb80ee778fb26b 356 Pfam PF07687 Peptidase dimerisation domain 157 247 7.0E-9 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain TO73_2284 d1eb6c9cfb3edf4a4acb80ee778fb26b 356 Pfam PF01546 Peptidase family M20/M25/M40 59 350 1.8E-28 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 TO73_0524 f438e4643aadd5f5ff4e29d53de70edd 189 SUPERFAMILY SSF52540 3 186 1.42E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0524 f438e4643aadd5f5ff4e29d53de70edd 189 Pfam PF00005 ABC transporter 18 141 6.1E-23 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0524 f438e4643aadd5f5ff4e29d53de70edd 189 SMART SM00382 27 189 1.0E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0524 f438e4643aadd5f5ff4e29d53de70edd 189 Gene3D G3DSA:3.40.50.300 1 189 3.2E-50 T 11-10-2018 TO73_0524 f438e4643aadd5f5ff4e29d53de70edd 189 ProSitePatterns PS00211 ABC transporters family signature. 115 129 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 SUPERFAMILY SSF82866 865 1093 2.35E-45 T 11-10-2018 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 SUPERFAMILY SSF82714 185 265 1.44E-9 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 SUPERFAMILY SSF82866 291 487 4.19E-41 T 11-10-2018 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 2.1E-39 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 2.1E-39 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 2.1E-39 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 2.1E-39 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 2.1E-39 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 2.1E-39 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 2.1E-39 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 SUPERFAMILY SSF82693 139 322 4.88E-19 T 11-10-2018 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 Gene3D G3DSA:1.20.1640.10 926 1100 2.7E-55 T 11-10-2018 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 Gene3D G3DSA:3.30.2090.10 184 268 1.1E-12 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 Gene3D G3DSA:3.30.70.1430 43 144 1.8E-25 T 11-10-2018 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 Gene3D G3DSA:1.20.1640.10 287 494 6.4E-44 T 11-10-2018 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 SUPERFAMILY SSF82714 785 867 3.4E-9 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 SUPERFAMILY SSF82693 628 710 1.67E-7 T 11-10-2018 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 SUPERFAMILY SSF82693 43 137 1.91E-26 T 11-10-2018 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 Pfam PF00873 AcrB/AcrD/AcrF family 7 485 6.6E-122 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TO73_0672 2cdb5dc27a3a74e666f733789efe5e3d 1101 Pfam PF00873 AcrB/AcrD/AcrF family 582 1088 8.2E-89 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TO73_0883 8a0259e146f223a6d5fc15d0c56fced9 309 SUPERFAMILY SSF53807 16 289 1.33E-44 T 11-10-2018 TO73_0883 8a0259e146f223a6d5fc15d0c56fced9 309 Gene3D G3DSA:3.40.50.1980 158 297 4.4E-28 T 11-10-2018 TO73_0883 8a0259e146f223a6d5fc15d0c56fced9 309 Pfam PF01497 Periplasmic binding protein 37 271 1.5E-24 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain TO73_0883 8a0259e146f223a6d5fc15d0c56fced9 309 Gene3D G3DSA:3.40.50.1980 34 154 1.3E-36 T 11-10-2018 TO73_0026 08ee4f17a1d1c0fa70e10c96c285520a 186 SUPERFAMILY SSF100950 5 185 5.36E-16 T 11-10-2018 IPR037171 NagB/RpiA transferase-like TO73_0026 08ee4f17a1d1c0fa70e10c96c285520a 186 Gene3D G3DSA:3.40.50.10420 34 185 8.7E-10 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TO73_0026 08ee4f17a1d1c0fa70e10c96c285520a 186 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 5 155 8.0E-13 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TO73_0121 3c76d35d339d77370afa60da9b635c4e 294 SUPERFAMILY SSF103481 49 144 2.09E-14 T 11-10-2018 TO73_0121 3c76d35d339d77370afa60da9b635c4e 294 SUPERFAMILY SSF103481 195 293 2.09E-11 T 11-10-2018 TO73_0121 3c76d35d339d77370afa60da9b635c4e 294 Pfam PF00892 EamA-like transporter family 16 140 8.2E-9 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_0121 3c76d35d339d77370afa60da9b635c4e 294 Pfam PF00892 EamA-like transporter family 154 289 6.1E-15 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_1465 aa6ab5e8c60f16aba1e15e7fc3bf3448 372 PIRSF PIRSF004762 2 372 1.7E-110 T 11-10-2018 TO73_1465 aa6ab5e8c60f16aba1e15e7fc3bf3448 372 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 12 364 3.0E-167 T 11-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TO73_1465 aa6ab5e8c60f16aba1e15e7fc3bf3448 372 Gene3D G3DSA:3.20.20.70 12 346 6.2E-53 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1465 aa6ab5e8c60f16aba1e15e7fc3bf3448 372 Pfam PF04055 Radical SAM superfamily 65 236 8.8E-13 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_1465 aa6ab5e8c60f16aba1e15e7fc3bf3448 372 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 56 363 3.9E-106 T 11-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 TO73_1465 aa6ab5e8c60f16aba1e15e7fc3bf3448 372 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 10 367 52.273 T 11-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TO73_1465 aa6ab5e8c60f16aba1e15e7fc3bf3448 372 SUPERFAMILY SSF102114 19 357 9.81E-55 T 11-10-2018 TO73_1465 aa6ab5e8c60f16aba1e15e7fc3bf3448 372 SMART SM00729 59 268 1.4E-5 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_2705 439345be7f6c8905dc482ad2d1b9a7a6 232 Gene3D G3DSA:1.10.10.10 172 219 2.8E-7 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2705 439345be7f6c8905dc482ad2d1b9a7a6 232 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 172 188 4.7E-6 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TO73_2705 439345be7f6c8905dc482ad2d1b9a7a6 232 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 198 217 4.7E-6 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TO73_2705 439345be7f6c8905dc482ad2d1b9a7a6 232 Pfam PF01022 Bacterial regulatory protein, arsR family 181 219 9.5E-7 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_2705 439345be7f6c8905dc482ad2d1b9a7a6 232 SUPERFAMILY SSF46785 173 228 4.55E-10 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0006 5a0415ce44d7e0991ff44debc812eded 260 SUPERFAMILY SSF102114 4 231 1.01E-37 T 11-10-2018 TO73_0006 5a0415ce44d7e0991ff44debc812eded 260 Pfam PF13186 Iron-sulfur cluster-binding domain 168 223 7.7E-5 T 11-10-2018 IPR023885 4Fe4S-binding SPASM domain TO73_0006 5a0415ce44d7e0991ff44debc812eded 260 Gene3D G3DSA:3.20.20.70 4 257 1.1E-18 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0261 6460a81c4297a38e9269b1e87f0cc908 379 SUPERFAMILY SSF53756 4 370 2.04E-42 T 11-10-2018 TO73_0261 6460a81c4297a38e9269b1e87f0cc908 379 Gene3D G3DSA:3.40.50.2000 100 366 4.6E-31 T 11-10-2018 TO73_0261 6460a81c4297a38e9269b1e87f0cc908 379 Gene3D G3DSA:3.40.50.2000 164 352 4.6E-31 T 11-10-2018 TO73_0261 6460a81c4297a38e9269b1e87f0cc908 379 Pfam PF13692 Glycosyl transferases group 1 187 335 1.5E-12 T 11-10-2018 TO73_0642 750ba1e1092b78d637102d06ec3f3c39 701 SUPERFAMILY SSF52540 10 631 2.82E-170 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0642 750ba1e1092b78d637102d06ec3f3c39 701 Gene3D G3DSA:3.40.50.300 286 622 2.6E-112 T 11-10-2018 TO73_0642 750ba1e1092b78d637102d06ec3f3c39 701 Pfam PF13361 UvrD-like helicase C-terminal domain 283 605 9.1E-68 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TO73_0642 750ba1e1092b78d637102d06ec3f3c39 701 Gene3D G3DSA:1.10.486.10 385 536 2.6E-112 T 11-10-2018 TO73_0642 750ba1e1092b78d637102d06ec3f3c39 701 Gene3D G3DSA:3.40.50.300 15 279 3.1E-100 T 11-10-2018 TO73_0642 750ba1e1092b78d637102d06ec3f3c39 701 Pfam PF00580 UvrD/REP helicase N-terminal domain 137 277 5.0E-36 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TO73_0642 750ba1e1092b78d637102d06ec3f3c39 701 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 132 1.7E-33 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TO73_0642 750ba1e1092b78d637102d06ec3f3c39 701 Gene3D G3DSA:1.10.10.160 115 195 3.1E-100 T 11-10-2018 IPR013986 DExx box DNA helicase domain superfamily TO73_1398 037a79e70e70fe9e84e7b779e2274944 343 SMART SM00829 8 339 1.8E-6 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TO73_1398 037a79e70e70fe9e84e7b779e2274944 343 SUPERFAMILY SSF51735 142 305 6.29E-30 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1398 037a79e70e70fe9e84e7b779e2274944 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TO73_1398 037a79e70e70fe9e84e7b779e2274944 343 Gene3D G3DSA:3.40.50.720 153 286 1.8E-130 T 11-10-2018 TO73_1398 037a79e70e70fe9e84e7b779e2274944 343 Pfam PF00107 Zinc-binding dehydrogenase 175 295 2.5E-15 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TO73_1398 037a79e70e70fe9e84e7b779e2274944 343 Gene3D G3DSA:3.90.180.10 17 333 1.8E-130 T 11-10-2018 TO73_1398 037a79e70e70fe9e84e7b779e2274944 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 132 5.0E-35 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TO73_1398 037a79e70e70fe9e84e7b779e2274944 343 SUPERFAMILY SSF50129 1 174 1.02E-55 T 11-10-2018 IPR011032 GroES-like superfamily TO73_0140 2c6eb8182ec6d1b6b87e90a61486aeee 367 Gene3D G3DSA:3.40.50.970 1 367 1.6E-127 T 11-10-2018 TO73_0140 2c6eb8182ec6d1b6b87e90a61486aeee 367 SUPERFAMILY SSF52518 32 365 8.58E-108 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_0140 2c6eb8182ec6d1b6b87e90a61486aeee 367 Pfam PF00676 Dehydrogenase E1 component 43 338 6.2E-86 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TO73_0002 f693e813273d0315089a935217fbe083 371 Gene3D G3DSA:3.10.150.10 256 371 8.2E-34 T 11-10-2018 TO73_0002 f693e813273d0315089a935217fbe083 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 253 370 4.1E-23 T 11-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TO73_0002 f693e813273d0315089a935217fbe083 371 SUPERFAMILY SSF55979 252 371 2.11E-25 T 11-10-2018 TO73_0002 f693e813273d0315089a935217fbe083 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 116 2.9E-13 T 11-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TO73_0002 f693e813273d0315089a935217fbe083 371 Gene3D G3DSA:3.10.150.10 1 120 3.2E-24 T 11-10-2018 TO73_0002 f693e813273d0315089a935217fbe083 371 SMART SM00480 17 367 3.6E-72 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TO73_0002 f693e813273d0315089a935217fbe083 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 250 2.6E-18 T 11-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 TO73_0002 f693e813273d0315089a935217fbe083 371 PIRSF PIRSF000804 1 371 1.8E-75 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TO73_0002 f693e813273d0315089a935217fbe083 371 SUPERFAMILY SSF55979 137 254 2.43E-15 T 11-10-2018 TO73_0002 f693e813273d0315089a935217fbe083 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 370 1.2E-60 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TO73_0002 f693e813273d0315089a935217fbe083 371 SUPERFAMILY SSF55979 1 115 1.99E-12 T 11-10-2018 TO73_0002 f693e813273d0315089a935217fbe083 371 Gene3D G3DSA:3.10.150.10 129 255 6.2E-27 T 11-10-2018 TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 Gene3D G3DSA:1.10.3730.10 158 259 5.7E-33 T 11-10-2018 TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 SUPERFAMILY SSF51735 1 153 1.24E-26 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 SUPERFAMILY SSF48179 154 259 7.14E-30 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 257 24.594 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 155 257 2.1E-34 T 11-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 PIRSF PIRSF000193 1 260 2.6E-62 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 4.1E-15 T 11-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 213 235 - T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 257 5.0E-75 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TO73_1689 fab5d87b8e195c81c7391ce1d6ff69bb 261 Gene3D G3DSA:3.40.50.720 1 157 1.4E-33 T 11-10-2018 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 Pfam PF02629 CoA binding domain 6 98 5.9E-32 T 11-10-2018 IPR003781 CoA-binding GO:0048037 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 2 287 7.5E-128 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 PIRSF PIRSF001553 1 288 9.8E-131 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 SUPERFAMILY SSF52210 122 284 2.22E-52 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 235 248 - T 11-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site TO73_1368 9e02986a6f9c201c4917482601aec74b 288 Gene3D G3DSA:3.40.50.261 123 288 2.8E-67 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 SMART SM00881 3 99 4.2E-37 T 11-10-2018 IPR003781 CoA-binding GO:0048037 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 Gene3D G3DSA:3.40.50.720 1 122 2.1E-50 T 11-10-2018 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 SUPERFAMILY SSF51735 2 120 2.58E-41 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1368 9e02986a6f9c201c4917482601aec74b 288 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 151 180 - T 11-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site TO73_1368 9e02986a6f9c201c4917482601aec74b 288 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 287 41.393 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 PRINTS PR01798 Succinyl-CoA synthase signature 176 194 7.7E-33 T 11-10-2018 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 PRINTS PR01798 Succinyl-CoA synthase signature 207 220 7.7E-33 T 11-10-2018 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 PRINTS PR01798 Succinyl-CoA synthase signature 81 98 7.7E-33 T 11-10-2018 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 PRINTS PR01798 Succinyl-CoA synthase signature 239 256 7.7E-33 T 11-10-2018 TO73_1368 9e02986a6f9c201c4917482601aec74b 288 Pfam PF00549 CoA-ligase 150 268 1.2E-15 T 11-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_1546 6460412e4f93319650f2e935b30ecbfe 372 Gene3D G3DSA:3.40.640.10 13 250 1.4E-131 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1546 6460412e4f93319650f2e935b30ecbfe 372 PIRSF PIRSF005572 1 372 1.7E-115 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TO73_1546 6460412e4f93319650f2e935b30ecbfe 372 SUPERFAMILY SSF53383 1 370 1.46E-102 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1546 6460412e4f93319650f2e935b30ecbfe 372 Gene3D G3DSA:3.90.1150.10 2 366 1.4E-131 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1546 6460412e4f93319650f2e935b30ecbfe 372 Pfam PF00266 Aminotransferase class-V 2 358 3.4E-72 T 11-10-2018 IPR000192 Aminotransferase class V domain TO73_1552 e5f50975dc0191f1bb5423417055b198 375 Pfam PF13286 Phosphohydrolase-associated domain 288 372 2.8E-25 T 11-10-2018 IPR026875 Phosphohydrolase-associated domain TO73_1552 e5f50975dc0191f1bb5423417055b198 375 SUPERFAMILY SSF109604 27 373 1.55E-83 T 11-10-2018 TO73_1552 e5f50975dc0191f1bb5423417055b198 375 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 16 374 37.499 T 11-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 TO73_1552 e5f50975dc0191f1bb5423417055b198 375 SMART SM00471 72 210 3.8E-13 T 11-10-2018 IPR003607 HD/PDEase domain TO73_1552 e5f50975dc0191f1bb5423417055b198 375 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 39 173 3.4E-60 T 11-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 TO73_1552 e5f50975dc0191f1bb5423417055b198 375 Gene3D G3DSA:1.10.3210.10 1 375 1.5E-152 T 11-10-2018 TO73_1552 e5f50975dc0191f1bb5423417055b198 375 Pfam PF01966 HD domain 76 200 5.6E-18 T 11-10-2018 IPR006674 HD domain TO73_1349 4854add29274a5d7f6d3a01d91e86607 552 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 360 481 3.2E-8 T 11-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TO73_1349 4854add29274a5d7f6d3a01d91e86607 552 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 4 195 13.399 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_1349 4854add29274a5d7f6d3a01d91e86607 552 PIRSF PIRSF026478 1 552 0.0 T 11-10-2018 IPR021194 Uncharacterised protein family, dehydrogenase DR0790 type, predicted TO73_1349 4854add29274a5d7f6d3a01d91e86607 552 SMART SM01207 7 187 1.9E-19 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_1349 4854add29274a5d7f6d3a01d91e86607 552 SUPERFAMILY SSF51735 354 478 4.13E-15 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1349 4854add29274a5d7f6d3a01d91e86607 552 Pfam PF02660 Glycerol-3-phosphate acyltransferase 8 186 2.9E-26 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_1349 4854add29274a5d7f6d3a01d91e86607 552 Gene3D G3DSA:3.40.50.720 346 487 6.1E-16 T 11-10-2018 TO73_1410 8ffe94ff9dd46894c365c9c9541b3249 403 SUPERFAMILY SSF53901 282 402 4.51E-35 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1410 8ffe94ff9dd46894c365c9c9541b3249 403 Pfam PF00108 Thiolase, N-terminal domain 11 273 4.4E-88 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TO73_1410 8ffe94ff9dd46894c365c9c9541b3249 403 Gene3D G3DSA:3.40.47.10 12 286 1.2E-140 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1410 8ffe94ff9dd46894c365c9c9541b3249 403 Pfam PF02803 Thiolase, C-terminal domain 281 402 1.9E-35 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TO73_1410 8ffe94ff9dd46894c365c9c9541b3249 403 PIRSF PIRSF000429 6 403 2.2E-127 T 11-10-2018 IPR002155 Thiolase GO:0016747 TO73_1410 8ffe94ff9dd46894c365c9c9541b3249 403 Gene3D G3DSA:3.40.47.10 133 399 1.2E-140 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1410 8ffe94ff9dd46894c365c9c9541b3249 403 ProSitePatterns PS00737 Thiolases signature 2. 349 365 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TO73_1410 8ffe94ff9dd46894c365c9c9541b3249 403 SUPERFAMILY SSF53901 10 280 1.15E-85 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1410 8ffe94ff9dd46894c365c9c9541b3249 403 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 13 401 2.3E-132 T 11-10-2018 IPR002155 Thiolase GO:0016747 TO73_0908 917c98c694802805b07bbbfc76365296 247 SMART SM00382 26 224 1.2E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0908 917c98c694802805b07bbbfc76365296 247 Gene3D G3DSA:3.40.50.300 1 247 1.4E-59 T 11-10-2018 TO73_0908 917c98c694802805b07bbbfc76365296 247 SUPERFAMILY SSF52540 2 241 3.28E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0908 917c98c694802805b07bbbfc76365296 247 Pfam PF00005 ABC transporter 19 175 2.9E-22 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0908 917c98c694802805b07bbbfc76365296 247 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_2279 b21260a10d1b044f84cf79a8a868ede3 249 SUPERFAMILY SSF56784 3 248 1.68E-40 T 11-10-2018 IPR036412 HAD-like superfamily TO73_2279 b21260a10d1b044f84cf79a8a868ede3 249 Gene3D G3DSA:1.20.120.1600 16 118 3.7E-41 T 11-10-2018 TO73_2279 b21260a10d1b044f84cf79a8a868ede3 249 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 121 221 8.6E-9 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_2279 b21260a10d1b044f84cf79a8a868ede3 249 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 123 215 6.9E-9 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_2279 b21260a10d1b044f84cf79a8a868ede3 249 Gene3D G3DSA:3.40.50.1000 6 241 3.7E-41 T 11-10-2018 IPR023214 HAD superfamily TO73_2279 b21260a10d1b044f84cf79a8a868ede3 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 146 2.4E-5 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_2279 b21260a10d1b044f84cf79a8a868ede3 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 182 202 2.4E-5 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_2279 b21260a10d1b044f84cf79a8a868ede3 249 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 180 2.4E-5 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_2279 b21260a10d1b044f84cf79a8a868ede3 249 Pfam PF13419 Haloacid dehalogenase-like hydrolase 116 221 1.3E-15 T 11-10-2018 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Pfam PF13487 HD domain 863 924 2.0E-22 T 11-10-2018 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Gene3D G3DSA:3.30.450.20 73 195 1.9E-17 T 11-10-2018 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SMART SM00065 471 617 0.011 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SMART SM00065 638 784 9.7E-17 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SUPERFAMILY SSF109604 789 974 6.85E-45 T 11-10-2018 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SUPERFAMILY SSF55785 74 195 2.54E-16 T 11-10-2018 IPR035965 PAS domain superfamily TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SUPERFAMILY SSF55785 325 447 2.09E-22 T 11-10-2018 IPR035965 PAS domain superfamily TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Gene3D G3DSA:3.30.450.20 196 317 1.9E-12 T 11-10-2018 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SUPERFAMILY SSF55785 238 332 1.57E-8 T 11-10-2018 IPR035965 PAS domain superfamily TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SUPERFAMILY SSF55781 604 776 4.36E-27 T 11-10-2018 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SMART SM00086 409 449 0.08 T 11-10-2018 IPR001610 PAC motif TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SMART SM00086 156 197 120.0 T 11-10-2018 IPR001610 PAC motif TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Pfam PF13185 GAF domain 638 775 3.9E-15 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Pfam PF13185 GAF domain 470 607 1.4E-7 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SMART SM00091 329 402 6.1E-10 T 11-10-2018 IPR000014 PAS domain TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SMART SM00091 81 149 1.9E-12 T 11-10-2018 IPR000014 PAS domain TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SMART SM00091 202 278 7.5 T 11-10-2018 IPR000014 PAS domain TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Pfam PF08447 PAS fold 238 307 5.9E-8 T 11-10-2018 IPR013655 PAS fold-3 GO:0005515 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Pfam PF08447 PAS fold 105 181 3.9E-9 T 11-10-2018 IPR013655 PAS fold-3 GO:0005515 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Pfam PF08447 PAS fold 359 429 1.2E-11 T 11-10-2018 IPR013655 PAS fold-3 GO:0005515 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 77 204 3.3E-11 T 11-10-2018 IPR000014 PAS domain TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 326 456 2.9E-23 T 11-10-2018 IPR000014 PAS domain TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Gene3D G3DSA:1.10.3210.10 788 976 8.1E-75 T 11-10-2018 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Gene3D G3DSA:3.30.450.40 617 787 2.8E-30 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Gene3D G3DSA:3.30.450.40 447 616 1.1E-19 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 Gene3D G3DSA:3.30.450.20 321 446 1.1E-22 T 11-10-2018 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 TIGRFAM TIGR00277 HDIG: HDIG domain 809 856 2.9E-7 T 11-10-2018 IPR006675 HDIG domain TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SUPERFAMILY SSF55781 453 631 2.84E-15 T 11-10-2018 TO73_1714 0c2bbac59cb22757a3746e6286996c62 978 SMART SM00471 808 943 5.7E-10 T 11-10-2018 IPR003607 HD/PDEase domain TO73_2155 31f981bef117b5301b1ddca0194550c4 156 ProSitePatterns PS00893 Nudix box signature. 31 52 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TO73_2155 31f981bef117b5301b1ddca0194550c4 156 SUPERFAMILY SSF55811 3 141 4.06E-29 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TO73_2155 31f981bef117b5301b1ddca0194550c4 156 Gene3D G3DSA:3.90.79.10 1 144 4.7E-39 T 11-10-2018 TO73_2155 31f981bef117b5301b1ddca0194550c4 156 Pfam PF00293 NUDIX domain 2 104 5.3E-14 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TO73_1184 ec127af577deec11eca167a50f6de779 502 Pfam PF06074 Protein of unknown function (DUF935) 3 492 2.1E-134 T 11-10-2018 IPR009279 Protein of unknown function DUF935 TO73_2161 ef85f719a4a29b42ccff922c511ec178 154 SUPERFAMILY SSF109604 29 154 2.69E-10 T 11-10-2018 TO73_2161 ef85f719a4a29b42ccff922c511ec178 154 Gene3D G3DSA:1.10.3210.10 21 146 2.4E-5 T 11-10-2018 TO73_1620 a1aaaf066f03838b645b63da0747f130 470 Gene3D G3DSA:3.40.50.200 133 466 9.7E-58 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_1620 a1aaaf066f03838b645b63da0747f130 470 PRINTS PR00723 Subtilisin serine protease family (S8) signature 400 416 1.8E-8 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_1620 a1aaaf066f03838b645b63da0747f130 470 PRINTS PR00723 Subtilisin serine protease family (S8) signature 223 236 1.8E-8 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_1620 a1aaaf066f03838b645b63da0747f130 470 PRINTS PR00723 Subtilisin serine protease family (S8) signature 170 189 1.8E-8 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_1620 a1aaaf066f03838b645b63da0747f130 470 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 401 411 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TO73_1620 a1aaaf066f03838b645b63da0747f130 470 Pfam PF00082 Subtilase family 174 442 2.0E-32 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TO73_1620 a1aaaf066f03838b645b63da0747f130 470 SUPERFAMILY SSF52743 150 463 3.8E-54 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_1955 a8f5118343b0455b6e06a206c372ef81 534 SUPERFAMILY SSF53955 386 532 2.72E-38 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily TO73_1955 a8f5118343b0455b6e06a206c372ef81 534 SUPERFAMILY SSF48452 155 282 4.22E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1955 a8f5118343b0455b6e06a206c372ef81 534 Gene3D G3DSA:1.25.40.10 139 281 1.5E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1955 a8f5118343b0455b6e06a206c372ef81 534 Gene3D G3DSA:1.10.530.10 381 533 2.1E-40 T 11-10-2018 TO73_1955 a8f5118343b0455b6e06a206c372ef81 534 Pfam PF01464 Transglycosylase SLT domain 392 500 2.3E-24 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 TO73_1007 eefc3871bbef89cc3414d10a701ec7f2 234 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 203 1.3E-43 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TO73_1007 eefc3871bbef89cc3414d10a701ec7f2 234 Gene3D G3DSA:3.40.1010.10 1 116 1.3E-44 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TO73_1007 eefc3871bbef89cc3414d10a701ec7f2 234 Gene3D G3DSA:3.30.950.10 117 233 1.5E-33 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TO73_1007 eefc3871bbef89cc3414d10a701ec7f2 234 SUPERFAMILY SSF53790 1 226 3.66E-63 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TO73_1007 eefc3871bbef89cc3414d10a701ec7f2 234 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 224 5.3E-63 T 11-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TO73_1007 eefc3871bbef89cc3414d10a701ec7f2 234 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 81 114 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 SUPERFAMILY SSF56645 3 241 3.53E-83 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 Gene3D G3DSA:1.20.140.10 236 381 8.2E-62 T 11-10-2018 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 Gene3D G3DSA:1.10.540.10 1 121 4.2E-41 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 116 1.1E-30 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 2.8E-26 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 PIRSF PIRSF016578 132 381 2.0E-17 T 11-10-2018 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 PIRSF PIRSF016578 4 85 2.1E-4 T 11-10-2018 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 SUPERFAMILY SSF47203 228 380 1.44E-63 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 Gene3D G3DSA:2.40.110.10 122 235 1.2E-43 T 11-10-2018 TO73_1043 96b1760b987867612bb2add8fbf15eca 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 379 6.8E-55 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TO73_2826 1b2822a7de83bbc34f09c3a0a5a509e4 188 Pfam PF08281 Sigma-70, region 4 129 181 1.5E-13 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TO73_2826 1b2822a7de83bbc34f09c3a0a5a509e4 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 184 2.0E-26 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TO73_2826 1b2822a7de83bbc34f09c3a0a5a509e4 188 Gene3D G3DSA:1.10.10.10 92 187 1.2E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2826 1b2822a7de83bbc34f09c3a0a5a509e4 188 SUPERFAMILY SSF88659 117 186 8.72E-15 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TO73_2826 1b2822a7de83bbc34f09c3a0a5a509e4 188 Pfam PF04542 Sigma-70 region 2 30 97 1.1E-16 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TO73_2826 1b2822a7de83bbc34f09c3a0a5a509e4 188 Gene3D G3DSA:1.10.1740.10 12 91 1.9E-23 T 11-10-2018 TO73_2826 1b2822a7de83bbc34f09c3a0a5a509e4 188 SUPERFAMILY SSF88946 6 116 1.33E-24 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TO73_2006 7dbcb279907d6e6aa255f36b2fb7de78 392 Pfam PF01385 Probable transposase 158 261 5.1E-11 T 11-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TO73_2006 7dbcb279907d6e6aa255f36b2fb7de78 392 Pfam PF07282 Putative transposase DNA-binding domain 284 350 1.7E-17 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_2006 7dbcb279907d6e6aa255f36b2fb7de78 392 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 232 309 4.7E-16 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_0146 6462349e0362884d23f74143ed99a1f2 126 PIRSF PIRSF004681 1 126 5.0E-37 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 TO73_0146 6462349e0362884d23f74143ed99a1f2 126 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 9 125 4.7E-34 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 TO73_0146 6462349e0362884d23f74143ed99a1f2 126 SUPERFAMILY SSF111038 6 125 4.06E-38 T 11-10-2018 IPR035917 YjbQ-like superfamily TO73_0146 6462349e0362884d23f74143ed99a1f2 126 Pfam PF01894 Uncharacterised protein family UPF0047 15 124 1.4E-31 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 TO73_0146 6462349e0362884d23f74143ed99a1f2 126 Gene3D G3DSA:2.60.120.460 1 126 3.9E-47 T 11-10-2018 IPR035917 YjbQ-like superfamily TO73_0773 09778f7bc8d81c0e520c50f3677d37ba 339 SUPERFAMILY SSF51735 1 186 2.94E-40 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0773 09778f7bc8d81c0e520c50f3677d37ba 339 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 263 3.5E-69 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TO73_0773 09778f7bc8d81c0e520c50f3677d37ba 339 SUPERFAMILY SSF51735 269 336 8.52E-14 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0773 09778f7bc8d81c0e520c50f3677d37ba 339 SUPERFAMILY SSF48179 211 263 4.59E-15 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TO73_0773 09778f7bc8d81c0e520c50f3677d37ba 339 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 212 260 2.2E-17 T 11-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TO73_0773 09778f7bc8d81c0e520c50f3677d37ba 339 Gene3D G3DSA:1.10.1040.10 222 264 6.5E-15 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TO73_0773 09778f7bc8d81c0e520c50f3677d37ba 339 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 179 4.7E-50 T 11-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TO73_0773 09778f7bc8d81c0e520c50f3677d37ba 339 Gene3D G3DSA:3.40.50.720 1 221 3.5E-64 T 11-10-2018 TO73_0773 09778f7bc8d81c0e520c50f3677d37ba 339 Gene3D G3DSA:3.40.50.720 265 338 3.7E-18 T 11-10-2018 TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 Gene3D G3DSA:3.90.226.10 1 194 5.4E-86 T 11-10-2018 TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 Pfam PF00574 Clp protease 12 191 9.3E-86 T 11-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 58 78 5.9E-50 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 18 33 5.9E-50 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 89 106 5.9E-50 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 167 186 5.9E-50 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 110 129 5.9E-50 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 111 124 - T 11-10-2018 IPR033135 ClpP, histidine active site TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 SUPERFAMILY SSF52096 10 193 5.41E-74 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 2 191 2.9E-95 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 2 192 43.86 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TO73_1137 121a93117e2ff43f4aee481d3c99e1b8 194 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 89 100 - T 11-10-2018 IPR018215 ClpP, Ser active site TO73_0141 6cadd1d81bdac5c9308a9b4fcb56a039 135 SUPERFAMILY SSF75217 2 133 6.54E-31 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases TO73_0141 6cadd1d81bdac5c9308a9b4fcb56a039 135 PIRSF PIRSF004505 1 134 3.8E-28 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TO73_0141 6cadd1d81bdac5c9308a9b4fcb56a039 135 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 134 21.62 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TO73_0141 6cadd1d81bdac5c9308a9b4fcb56a039 135 Gene3D G3DSA:3.40.1280.10 1 134 9.5E-35 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TO73_0141 6cadd1d81bdac5c9308a9b4fcb56a039 135 Pfam PF02590 Predicted SPOUT methyltransferase 2 133 4.5E-29 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TO73_2129 9cdee716ad6f79d3ffbb4b810d75869e 90 SUPERFAMILY SSF140663 3 89 1.96E-26 T 11-10-2018 IPR023203 TTHA0068-like superfamily TO73_2129 9cdee716ad6f79d3ffbb4b810d75869e 90 Pfam PF03745 Domain of unknown function (DUF309) 4 50 3.9E-19 T 11-10-2018 IPR005500 Protein of unknown function DUF309 TO73_2129 9cdee716ad6f79d3ffbb4b810d75869e 90 Gene3D G3DSA:1.20.58.500 1 90 2.0E-30 T 11-10-2018 TO73_1504 45d8748cb9c7161113a51f20c512fcb5 370 Pfam PF01266 FAD dependent oxidoreductase 4 338 4.8E-60 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TO73_1504 45d8748cb9c7161113a51f20c512fcb5 370 Gene3D G3DSA:3.30.9.10 78 301 2.3E-91 T 11-10-2018 TO73_1504 45d8748cb9c7161113a51f20c512fcb5 370 SUPERFAMILY SSF51905 3 360 3.24E-49 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1504 45d8748cb9c7161113a51f20c512fcb5 370 Gene3D G3DSA:3.50.50.60 3 338 2.3E-91 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0339 c9cea3ab3415802c50783fee551683d9 190 SUPERFAMILY SSF103473 8 172 2.22E-7 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_0339 c9cea3ab3415802c50783fee551683d9 190 Gene3D G3DSA:1.20.1250.20 4 173 1.5E-5 T 11-10-2018 TO73_0420 eeb7656b1486bf22fb29aa35e32770eb 340 Gene3D G3DSA:3.40.910.10 5 326 3.6E-91 T 11-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 TO73_0420 eeb7656b1486bf22fb29aa35e32770eb 340 Pfam PF01916 Deoxyhypusine synthase 24 317 3.3E-92 T 11-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TO73_0420 eeb7656b1486bf22fb29aa35e32770eb 340 Hamap MF_00640 Deoxyhypusine synthase-like protein. 3 340 45.524 T 11-10-2018 IPR023496 Deoxyhypusine synthase-like GO:0016765 TO73_0420 eeb7656b1486bf22fb29aa35e32770eb 340 SUPERFAMILY SSF52467 2 328 7.85E-99 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 PRINTS PR01038 Arginyl-tRNA synthetase signature 143 156 1.7E-19 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 PRINTS PR01038 Arginyl-tRNA synthetase signature 291 312 1.7E-19 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 PRINTS PR01038 Arginyl-tRNA synthetase signature 104 119 1.7E-19 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 135 1.7E-19 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 SMART SM01016 2 82 4.4E-18 T 11-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 SUPERFAMILY SSF52374 98 466 5.91E-73 T 11-10-2018 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 Gene3D G3DSA:1.10.730.10 477 592 4.5E-37 T 11-10-2018 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 Pfam PF00750 tRNA synthetases class I (R) 104 307 8.8E-13 T 11-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 Pfam PF00750 tRNA synthetases class I (R) 345 446 8.1E-10 T 11-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 Hamap MF_00123 Arginine--tRNA ligase [argS]. 4 592 22.446 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 Gene3D G3DSA:3.40.50.620 104 476 4.7E-110 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 114 123 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 Pfam PF05746 DALR anticodon binding domain 473 592 2.3E-30 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 SMART SM00836 473 592 2.7E-30 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 SUPERFAMILY SSF55190 3 91 7.06E-18 T 11-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 SUPERFAMILY SSF47323 467 592 1.63E-30 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 6 82 4.6E-14 T 11-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1514 b8b59a553f1e0dcb607462115fa95db2 592 Gene3D G3DSA:3.30.1360.70 1 98 1.6E-19 T 11-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TO73_2390 0c4d7344acac37f90ef042e36901de91 249 Gene3D G3DSA:3.40.50.300 2 248 4.0E-86 T 11-10-2018 TO73_2390 0c4d7344acac37f90ef042e36901de91 249 SUPERFAMILY SSF52540 7 246 1.55E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2390 0c4d7344acac37f90ef042e36901de91 249 Pfam PF13614 AAA domain 7 170 5.2E-45 T 11-10-2018 IPR025669 AAA domain TO73_2390 0c4d7344acac37f90ef042e36901de91 249 PIRSF PIRSF009320 6 248 1.5E-26 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 Pfam PF00204 DNA gyrase B 225 394 1.0E-52 T 11-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 224 246 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 364 378 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 185 200 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 378 398 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 9 19 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 316 332 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 474 483 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 595 607 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 611 627 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR01159 DNA gyrase subunit B signature 200 213 1.1E-51 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 11-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 SUPERFAMILY SSF54211 225 395 5.5E-50 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR00418 DNA topoisomerase II family signature 574 590 1.7E-69 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR00418 DNA topoisomerase II family signature 38 53 1.7E-69 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR00418 DNA topoisomerase II family signature 116 130 1.7E-69 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR00418 DNA topoisomerase II family signature 513 530 1.7E-69 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR00418 DNA topoisomerase II family signature 424 438 1.7E-69 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR00418 DNA topoisomerase II family signature 73 86 1.7E-69 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR00418 DNA topoisomerase II family signature 533 545 1.7E-69 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR00418 DNA topoisomerase II family signature 495 511 1.7E-69 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 PRINTS PR00418 DNA topoisomerase II family signature 272 285 1.7E-69 T 11-10-2018 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 SUPERFAMILY SSF56719 398 635 7.32E-88 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 Gene3D G3DSA:3.30.230.10 224 396 6.5E-65 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 SMART SM00387 34 180 2.3E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 Gene3D G3DSA:3.40.50.670 402 641 1.1E-106 T 11-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 570 631 1.6E-29 T 11-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 179 4.7E-19 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 Gene3D G3DSA:3.30.565.10 16 223 5.7E-83 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 Pfam PF01751 Toprim domain 423 539 7.5E-19 T 11-10-2018 IPR006171 TOPRIM domain TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 SUPERFAMILY SSF55874 9 218 5.11E-67 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_2038 3f9b41350875d88118538d9e877fe9d3 641 SMART SM00433 38 635 0.0 T 11-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 14 30 - T 11-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 7 497 1.4E-202 T 11-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 201 214 - T 11-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 SUPERFAMILY SSF110921 395 499 7.72E-21 T 11-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 4 511 40.447 T 11-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 Gene3D G3DSA:1.10.238.260 282 392 3.8E-35 T 11-10-2018 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 Pfam PF00682 HMGL-like 7 275 2.0E-91 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 SMART SM00917 372 502 5.0E-32 T 11-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 Gene3D G3DSA:3.20.20.70 3 278 2.3E-106 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 Pfam PF08502 LeuA allosteric (dimerisation) domain 374 500 1.2E-29 T 11-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 SUPERFAMILY SSF51569 4 293 2.75E-95 T 11-10-2018 TO73_1340 393a6cac5e5ccb059adb5ec8c9d626de 520 Gene3D G3DSA:3.30.160.270 396 502 1.6E-6 T 11-10-2018 TO73_0777 780cc6e0bb4c80607c3560ec6791873e 396 Pfam PF13579 Glycosyl transferase 4-like domain 21 197 1.0E-13 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TO73_0777 780cc6e0bb4c80607c3560ec6791873e 396 Gene3D G3DSA:3.40.50.2000 207 363 1.3E-39 T 11-10-2018 TO73_0777 780cc6e0bb4c80607c3560ec6791873e 396 SUPERFAMILY SSF53756 7 385 2.7E-71 T 11-10-2018 TO73_0777 780cc6e0bb4c80607c3560ec6791873e 396 Pfam PF00534 Glycosyl transferases group 1 212 359 5.2E-28 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 SMART SM00306 814 914 2.7E-16 T 11-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1219 1241 5.2E-7 T 11-10-2018 IPR030934 Intein C-terminal splicing region TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Pfam PF14528 LAGLIDADG-like domain 1029 1107 2.1E-11 T 11-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Pfam PF14890 Intein splicing domain 828 1240 2.5E-29 T 11-10-2018 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Gene3D G3DSA:3.20.20.140 1 284 4.5E-108 T 11-10-2018 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 SMART SM00481 8 77 2.0E-26 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Gene3D G3DSA:2.170.16.10 1147 1240 4.2E-16 T 11-10-2018 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Pfam PF14579 Helix-hairpin-helix motif 1290 1376 1.9E-27 T 11-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 SUPERFAMILY SSF89550 6 261 1.29E-28 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 PRINTS PR00379 Intein signature 881 894 6.7E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 PRINTS PR00379 Intein signature 1217 1234 6.7E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 PRINTS PR00379 Intein signature 1235 1244 6.7E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 PRINTS PR00379 Intein signature 1029 1041 6.7E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 PRINTS PR00379 Intein signature 1057 1072 6.7E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 PRINTS PR00379 Intein signature 928 940 6.7E-20 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 816 894 3.3E-8 T 11-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Gene3D G3DSA:2.170.16.10 814 930 2.8E-23 T 11-10-2018 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 357 791 1.7E-166 T 11-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 SUPERFAMILY SSF160975 1316 1363 3.53E-6 T 11-10-2018 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Gene3D G3DSA:3.10.28.10 931 1093 1.4E-23 T 11-10-2018 IPR027434 Homing endonuclease TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Pfam PF02811 PHP domain 9 184 1.2E-48 T 11-10-2018 IPR004013 PHP domain GO:0003824 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 356 819 3.1E-206 T 11-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Gene3D G3DSA:1.10.10.1600 496 571 5.1E-28 T 11-10-2018 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 SUPERFAMILY SSF55608 1016 1116 1.19E-11 T 11-10-2018 IPR027434 Homing endonuclease TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 SUPERFAMILY SSF51294 815 1240 4.12E-43 T 11-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 Gene3D G3DSA:1.10.150.870 1256 1367 6.4E-8 T 11-10-2018 TO73_0028 32ecdc3667778632583b5247a2a0cfe8 1645 SMART SM00305 1201 1246 3.2E-13 T 11-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_2216 13c4a8a4bd51dc3d217a989e903c720c 73 Gene3D G3DSA:3.30.2390.10 1 73 5.2E-32 T 11-10-2018 TO73_2216 13c4a8a4bd51dc3d217a989e903c720c 73 SUPERFAMILY SSF143100 5 64 7.72E-15 T 11-10-2018 IPR035069 TTHA1013/TTHA0281-like TO73_2216 13c4a8a4bd51dc3d217a989e903c720c 73 Pfam PF08972 Domain of unknown function (DUF1902) 3 70 9.8E-28 T 11-10-2018 IPR015066 Domain of unknown function DUF1902 TO73_2016 4f4a60a4ae59825e5bd46dde8b4b840b 521 SMART SM01120 34 194 4.2E-61 T 11-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TO73_2016 4f4a60a4ae59825e5bd46dde8b4b840b 521 SMART SM01121 219 521 4.1E-125 T 11-10-2018 IPR033470 Uncharacterised protein, DhaK domain TO73_2016 4f4a60a4ae59825e5bd46dde8b4b840b 521 Gene3D G3DSA:1.25.40.340 24 186 1.1E-8 T 11-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TO73_2016 4f4a60a4ae59825e5bd46dde8b4b840b 521 Pfam PF13684 Dihydroxyacetone kinase family 219 517 4.5E-81 T 11-10-2018 IPR033470 Uncharacterised protein, DhaK domain TO73_2016 4f4a60a4ae59825e5bd46dde8b4b840b 521 Pfam PF02734 DAK2 domain 34 192 3.1E-40 T 11-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TO73_2016 4f4a60a4ae59825e5bd46dde8b4b840b 521 SUPERFAMILY SSF101473 8 194 1.96E-40 T 11-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TO73_2016 4f4a60a4ae59825e5bd46dde8b4b840b 521 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 10 520 7.3E-165 T 11-10-2018 IPR019986 DAK2 domain-containing protein YloV TO73_1919 ca8c8f988a0b0af0d525a6f31f6986ba 59 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 47 3.0E-10 T 11-10-2018 IPR025161 Putative transposase IS4/IS5 family TO73_1939 ca8c8f988a0b0af0d525a6f31f6986ba 59 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 47 3.0E-10 T 11-10-2018 IPR025161 Putative transposase IS4/IS5 family TO73_2407 785b8b2657704f3252e3d5e59521940a 193 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 191 2.8E-45 T 11-10-2018 TO73_2407 785b8b2657704f3252e3d5e59521940a 193 SUPERFAMILY SSF53335 3 179 1.43E-41 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2407 785b8b2657704f3252e3d5e59521940a 193 Gene3D G3DSA:3.40.50.150 4 193 7.4E-58 T 11-10-2018 TO73_2874 e132b80f0262669993e6a1724d3a3236 323 SUPERFAMILY SSF52540 60 308 1.28E-35 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2874 e132b80f0262669993e6a1724d3a3236 323 Pfam PF12728 Helix-turn-helix domain 10 46 2.3E-6 T 11-10-2018 TO73_2874 e132b80f0262669993e6a1724d3a3236 323 Gene3D G3DSA:3.40.50.300 49 315 1.8E-45 T 11-10-2018 TO73_2874 e132b80f0262669993e6a1724d3a3236 323 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 10 42 7.0E-8 T 11-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TO73_2874 e132b80f0262669993e6a1724d3a3236 323 Gene3D G3DSA:1.10.1660.10 4 45 4.3E-7 T 11-10-2018 TO73_2874 e132b80f0262669993e6a1724d3a3236 323 Pfam PF13614 AAA domain 61 216 7.9E-30 T 11-10-2018 IPR025669 AAA domain TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 102 110 - T 11-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 SUPERFAMILY SSF53448 3 284 1.97E-78 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 200 210 - T 11-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 SUPERFAMILY SSF51161 302 412 4.21E-19 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 Gene3D G3DSA:3.90.550.10 2 295 7.5E-90 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 11-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 414 49.865 T 11-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 Gene3D G3DSA:2.160.10.10 296 412 6.8E-33 T 11-10-2018 TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 387 2.1E-148 T 11-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TO73_0352 ee9da63369ff6480b5f4af652fa5bece 414 Pfam PF00483 Nucleotidyl transferase 8 280 5.4E-66 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TO73_1597 69e6ce118fbbb14f5e835e4b3154881d 188 SUPERFAMILY SSF160527 78 188 3.53E-14 T 11-10-2018 TO73_1597 69e6ce118fbbb14f5e835e4b3154881d 188 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 188 10.699 T 11-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1597 69e6ce118fbbb14f5e835e4b3154881d 188 Gene3D G3DSA:1.20.5.620 2 97 4.8E-24 T 11-10-2018 TO73_1597 69e6ce118fbbb14f5e835e4b3154881d 188 Pfam PF01991 ATP synthase (E/31 kDa) subunit 9 121 1.7E-5 T 11-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1597 69e6ce118fbbb14f5e835e4b3154881d 188 Gene3D G3DSA:3.30.2320.30 98 188 6.4E-21 T 11-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_0296 821c7719945aa1784ed012e943a8f860 443 Gene3D G3DSA:3.50.50.60 115 439 1.5E-159 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0296 821c7719945aa1784ed012e943a8f860 443 SUPERFAMILY SSF51905 2 316 7.45E-50 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0296 821c7719945aa1784ed012e943a8f860 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.9E-20 T 11-10-2018 TO73_0296 821c7719945aa1784ed012e943a8f860 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 2.9E-20 T 11-10-2018 TO73_0296 821c7719945aa1784ed012e943a8f860 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 2.9E-20 T 11-10-2018 TO73_0296 821c7719945aa1784ed012e943a8f860 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 2.9E-20 T 11-10-2018 TO73_0296 821c7719945aa1784ed012e943a8f860 443 SUPERFAMILY SSF55424 322 441 5.33E-27 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TO73_0296 821c7719945aa1784ed012e943a8f860 443 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 291 2.0E-68 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TO73_0296 821c7719945aa1784ed012e943a8f860 443 Gene3D G3DSA:3.50.50.60 4 339 1.5E-159 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0296 821c7719945aa1784ed012e943a8f860 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 8.1E-29 T 11-10-2018 TO73_0296 821c7719945aa1784ed012e943a8f860 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 8.1E-29 T 11-10-2018 TO73_0296 821c7719945aa1784ed012e943a8f860 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 8.1E-29 T 11-10-2018 TO73_0296 821c7719945aa1784ed012e943a8f860 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.1E-29 T 11-10-2018 TO73_0296 821c7719945aa1784ed012e943a8f860 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 8.1E-29 T 11-10-2018 TO73_0296 821c7719945aa1784ed012e943a8f860 443 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 430 5.1E-14 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 604 646 8.3E-10 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 547 596 1.6E-12 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 651 698 1.8E-12 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 751 6.1E-11 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 498 543 1.3E-11 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 756 801 2.7E-13 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 SUPERFAMILY SSF56719 26 479 1.27E-171 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 SUPERFAMILY SSF101904 492 803 4.19E-93 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 803 23.594 T 11-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Gene3D G3DSA:3.30.1360.40 231 326 1.8E-205 T 11-10-2018 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 SMART SM00434 7 458 7.8E-267 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Gene3D G3DSA:2.120.10.90 490 801 2.1E-111 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 5 798 0.0 T 11-10-2018 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 457 3.4E-155 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Gene3D G3DSA:1.10.268.10 363 451 1.8E-205 T 11-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TO73_0585 bd4692e86472258e1a13b98bf02d528f 805 Gene3D G3DSA:3.90.199.10 28 479 1.8E-205 T 11-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TO73_1928 111f95b52ec7e8e7223762c9a8524dff 290 SUPERFAMILY SSF53697 5 283 2.89E-53 T 11-10-2018 TO73_1928 111f95b52ec7e8e7223762c9a8524dff 290 Gene3D G3DSA:3.40.50.10490 142 274 2.5E-60 T 11-10-2018 TO73_1928 111f95b52ec7e8e7223762c9a8524dff 290 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 149 288 2.3E-23 T 11-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TO73_1928 111f95b52ec7e8e7223762c9a8524dff 290 Gene3D G3DSA:3.40.50.10920 16 141 1.4E-59 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 PRINTS PR01874 DNA repair protein radA signature 157 181 4.4E-76 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 PRINTS PR01874 DNA repair protein radA signature 303 326 4.4E-76 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 PRINTS PR01874 DNA repair protein radA signature 8 32 4.4E-76 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 PRINTS PR01874 DNA repair protein radA signature 196 224 4.4E-76 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 PRINTS PR01874 DNA repair protein radA signature 112 129 4.4E-76 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 PRINTS PR01874 DNA repair protein radA signature 229 255 4.4E-76 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 PRINTS PR01874 DNA repair protein radA signature 73 101 4.4E-76 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 SUPERFAMILY SSF52540 60 274 1.09E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 SMART SM00382 81 227 1.2E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 Pfam PF13481 AAA domain 68 205 1.1E-12 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 SUPERFAMILY SSF54211 236 410 9.1E-30 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 Pfam PF13541 Subunit ChlI of Mg-chelatase 327 408 6.0E-7 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 Gene3D G3DSA:3.30.230.10 275 420 7.0E-12 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 Hamap MF_01498 DNA repair protein RadA [radA]. 19 422 40.961 T 11-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 Gene3D G3DSA:3.40.50.300 54 261 9.0E-36 T 11-10-2018 TO73_1364 6d488d210b176995ef04ed0786cf6a95 423 TIGRFAM TIGR00416 sms: DNA repair protein RadA 2 411 5.6E-136 T 11-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 SUPERFAMILY SSF74731 2 116 2.35E-47 T 11-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.0E-51 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 Pfam PF00453 Ribosomal protein L20 3 109 4.2E-48 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 7.0E-17 T 11-10-2018 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 Gene3D G3DSA:1.10.1900.20 56 117 8.2E-32 T 11-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.4E-39 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.4E-39 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.4E-39 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.67 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1351 d30dbabdebb5c4c02218f4c99c4ed469 118 Gene3D G3DSA:1.10.720.90 2 55 2.3E-23 T 11-10-2018 TO73_1676 47f87e2fbedaba603712237d6c51f058 305 Gene3D G3DSA:1.10.443.10 188 303 7.7E-18 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TO73_1676 47f87e2fbedaba603712237d6c51f058 305 Gene3D G3DSA:1.10.150.130 66 185 2.8E-22 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal TO73_1676 47f87e2fbedaba603712237d6c51f058 305 Pfam PF00589 Phage integrase family 187 277 2.9E-5 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TO73_1676 47f87e2fbedaba603712237d6c51f058 305 SUPERFAMILY SSF56349 70 301 1.5E-40 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 6.2E-63 T 11-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 Gene3D G3DSA:1.10.3730.40 182 336 2.8E-67 T 11-10-2018 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 4.6E-77 T 11-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 Gene3D G3DSA:3.40.50.720 1 181 8.3E-79 T 11-10-2018 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 PIRSF PIRSF000116 4 206 7.5E-47 T 11-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 PIRSF PIRSF000116 202 333 4.5E-15 T 11-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 328 3.7E-137 T 11-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 SUPERFAMILY SSF48179 183 330 3.06E-67 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 329 45.671 T 11-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TO73_1341 78cbedaa4b3c6aa96ac90da038b9634a 337 SUPERFAMILY SSF51735 1 182 2.75E-76 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1803 d43b7849cdee26d3ee74833f07a7ba83 205 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 17 87 2.0E-30 T 11-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TO73_1803 d43b7849cdee26d3ee74833f07a7ba83 205 Gene3D G3DSA:2.40.240.10 1 90 1.8E-31 T 11-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1803 d43b7849cdee26d3ee74833f07a7ba83 205 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 177 23.558 T 11-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TO73_1803 d43b7849cdee26d3ee74833f07a7ba83 205 SUPERFAMILY SSF50715 1 181 5.41E-51 T 11-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1803 d43b7849cdee26d3ee74833f07a7ba83 205 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 94 176 8.3E-29 T 11-10-2018 IPR020057 Ribosomal protein L25, beta domain TO73_1803 d43b7849cdee26d3ee74833f07a7ba83 205 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 16 174 2.4E-40 T 11-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TO73_1803 d43b7849cdee26d3ee74833f07a7ba83 205 Gene3D G3DSA:2.170.120.20 91 184 9.7E-35 T 11-10-2018 IPR037121 Ribosomal protein L25, C-terminal TO73_1803 d43b7849cdee26d3ee74833f07a7ba83 205 Pfam PF01386 Ribosomal L25p family 6 87 2.0E-12 T 11-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 245 492 6.1E-63 T 11-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 SUPERFAMILY SSF160467 4 82 3.27E-14 T 11-10-2018 TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 Gene3D G3DSA:2.40.100.10 76 208 8.4E-53 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 SMART SM00796 2 189 6.5E-66 T 11-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 SMART SM00797 244 493 2.2E-57 T 11-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 Gene3D G3DSA:3.30.1360.40 1 72 1.1E-27 T 11-10-2018 TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 Gene3D G3DSA:2.40.100.10 384 493 6.0E-33 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 7 197 1.9E-44 T 11-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 5 189 9.9E-59 T 11-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TO73_1025 4dba08d0fd83b0a211c1daccbee0fa53 494 SUPERFAMILY SSF50891 78 199 2.31E-38 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily TO73_0465 0338f133ec4363d1c32f8cbfa4d3b89f 94 Gene3D G3DSA:3.20.20.60 9 94 1.4E-21 T 11-10-2018 TO73_0465 0338f133ec4363d1c32f8cbfa4d3b89f 94 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 11 90 1.0E-16 T 11-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TO73_0465 0338f133ec4363d1c32f8cbfa4d3b89f 94 SUPERFAMILY SSF51621 10 91 6.28E-21 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TO73_2003 8c0dc0a9102b582a717e6c5dcbef72b1 381 Gene3D G3DSA:3.30.750.80 69 170 2.0E-37 T 11-10-2018 TO73_2003 8c0dc0a9102b582a717e6c5dcbef72b1 381 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 162 349 5.9E-8 T 11-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TO73_2003 8c0dc0a9102b582a717e6c5dcbef72b1 381 Gene3D G3DSA:3.40.50.150 171 380 2.7E-60 T 11-10-2018 TO73_2003 8c0dc0a9102b582a717e6c5dcbef72b1 381 SUPERFAMILY SSF88697 3 66 6.46E-6 T 11-10-2018 IPR015947 PUA-like superfamily TO73_2003 8c0dc0a9102b582a717e6c5dcbef72b1 381 SUPERFAMILY SSF53335 74 375 1.66E-58 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2003 8c0dc0a9102b582a717e6c5dcbef72b1 381 Gene3D G3DSA:2.30.130.10 1 68 8.5E-19 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 TO73_0991 49a1639610a1e1977c815dd5a8b7c886 663 Pfam PF00171 Aldehyde dehydrogenase family 16 442 6.6E-57 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TO73_0991 49a1639610a1e1977c815dd5a8b7c886 663 SUPERFAMILY SSF54637 517 662 2.77E-41 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_0991 49a1639610a1e1977c815dd5a8b7c886 663 Gene3D G3DSA:3.10.129.10 518 663 7.7E-47 T 11-10-2018 TO73_0991 49a1639610a1e1977c815dd5a8b7c886 663 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 4 660 0.0 T 11-10-2018 IPR011966 Phenylacetic acid degradation protein PaaN KEGG: 00360+3.3.2.12+1.2.1.91 TO73_0991 49a1639610a1e1977c815dd5a8b7c886 663 SUPERFAMILY SSF53720 3 486 3.67E-72 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TO73_0991 49a1639610a1e1977c815dd5a8b7c886 663 Gene3D G3DSA:3.40.309.10 257 464 2.6E-128 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TO73_0991 49a1639610a1e1977c815dd5a8b7c886 663 Pfam PF01575 MaoC like domain 528 640 4.2E-27 T 11-10-2018 IPR002539 MaoC-like dehydratase domain TO73_0991 49a1639610a1e1977c815dd5a8b7c886 663 Gene3D G3DSA:3.40.605.10 10 475 2.6E-128 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TO73_0991 49a1639610a1e1977c815dd5a8b7c886 663 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TO73_0745 63ce91dffadf2108dfe52d0a7c9e6dab 295 Pfam PF00326 Prolyl oligopeptidase family 99 294 5.1E-12 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TO73_0745 63ce91dffadf2108dfe52d0a7c9e6dab 295 Gene3D G3DSA:3.40.50.1820 25 295 2.4E-44 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0745 63ce91dffadf2108dfe52d0a7c9e6dab 295 SUPERFAMILY SSF53474 15 294 3.92E-47 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0937 2d71ccb094e365888828b3c9376feeff 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0937 2d71ccb094e365888828b3c9376feeff 234 Gene3D G3DSA:3.40.50.300 1 234 3.2E-57 T 11-10-2018 TO73_0937 2d71ccb094e365888828b3c9376feeff 234 SMART SM00382 27 213 3.5E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0937 2d71ccb094e365888828b3c9376feeff 234 SUPERFAMILY SSF52540 3 232 1.17E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0937 2d71ccb094e365888828b3c9376feeff 234 Pfam PF00005 ABC transporter 20 162 1.3E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0663 f3175542882b7d6d9c5b57ba38603e3c 305 Gene3D G3DSA:3.40.366.10 5 278 1.1E-106 T 11-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TO73_0663 f3175542882b7d6d9c5b57ba38603e3c 305 SUPERFAMILY SSF55048 125 190 8.24E-16 T 11-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TO73_0663 f3175542882b7d6d9c5b57ba38603e3c 305 Pfam PF00698 Acyl transferase domain 5 288 7.1E-43 T 11-10-2018 IPR014043 Acyl transferase TO73_0663 f3175542882b7d6d9c5b57ba38603e3c 305 PIRSF PIRSF000446 1 304 1.0E-89 T 11-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TO73_0663 f3175542882b7d6d9c5b57ba38603e3c 305 Gene3D G3DSA:3.30.70.250 122 190 1.1E-106 T 11-10-2018 TO73_0663 f3175542882b7d6d9c5b57ba38603e3c 305 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 300 4.2E-44 T 11-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TO73_0663 f3175542882b7d6d9c5b57ba38603e3c 305 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 284 1.3E-92 T 11-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TO73_0663 f3175542882b7d6d9c5b57ba38603e3c 305 SUPERFAMILY SSF52151 1 303 6.02E-68 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TO73_0667 fdfc69836605848bd5dbce1e4156af71 288 SUPERFAMILY SSF52768 3 286 5.58E-91 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily TO73_0667 fdfc69836605848bd5dbce1e4156af71 288 TIGRFAM TIGR01229 rocF_arginase: arginase 6 286 2.0E-90 T 11-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 TO73_0667 fdfc69836605848bd5dbce1e4156af71 288 PRINTS PR00116 Arginase signature 210 239 6.2E-33 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 TO73_0667 fdfc69836605848bd5dbce1e4156af71 288 PRINTS PR00116 Arginase signature 163 181 6.2E-33 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 TO73_0667 fdfc69836605848bd5dbce1e4156af71 288 PRINTS PR00116 Arginase signature 91 106 6.2E-33 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 TO73_0667 fdfc69836605848bd5dbce1e4156af71 288 PRINTS PR00116 Arginase signature 245 259 6.2E-33 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 TO73_0667 fdfc69836605848bd5dbce1e4156af71 288 Gene3D G3DSA:3.40.800.10 2 288 6.4E-118 T 11-10-2018 TO73_0667 fdfc69836605848bd5dbce1e4156af71 288 PIRSF PIRSF036979 1 285 2.7E-38 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 TO73_0667 fdfc69836605848bd5dbce1e4156af71 288 Pfam PF00491 Arginase family 3 283 2.2E-78 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 147 1.1E-42 T 11-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 Gene3D G3DSA:3.40.50.1370 137 287 7.7E-109 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 Gene3D G3DSA:3.40.50.1370 20 296 7.7E-109 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 9 301 73.326 T 11-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 217 227 3.7E-23 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 3.7E-23 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 3.7E-23 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 3.7E-23 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 3.7E-23 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 3.3E-22 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 3.3E-22 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 3.3E-22 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 3.3E-22 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 10 300 2.5E-107 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 153 298 2.4E-45 T 11-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TO73_1327 4fc8bce4f8a76b743f308647e75b4caf 301 SUPERFAMILY SSF53671 8 300 2.88E-90 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TO73_1247 bd189e81589eb773f70a3a7bf78bea55 283 Gene3D G3DSA:3.40.50.280 160 283 9.8E-33 T 11-10-2018 TO73_1247 bd189e81589eb773f70a3a7bf78bea55 283 Pfam PF02310 B12 binding domain 167 263 8.6E-7 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TO73_1247 bd189e81589eb773f70a3a7bf78bea55 283 SUPERFAMILY SSF46955 7 75 1.1E-15 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily TO73_1247 bd189e81589eb773f70a3a7bf78bea55 283 Gene3D G3DSA:1.10.1240.10 81 159 2.3E-25 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1247 bd189e81589eb773f70a3a7bf78bea55 283 SUPERFAMILY SSF52242 162 263 2.04E-12 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TO73_1247 bd189e81589eb773f70a3a7bf78bea55 283 Pfam PF13411 MerR HTH family regulatory protein 7 75 3.3E-17 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TO73_1247 bd189e81589eb773f70a3a7bf78bea55 283 SMART SM00422 7 77 8.3E-11 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TO73_1247 bd189e81589eb773f70a3a7bf78bea55 283 Pfam PF02607 B12 binding domain 84 155 6.9E-10 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_1247 bd189e81589eb773f70a3a7bf78bea55 283 Gene3D G3DSA:1.10.1660.10 1 77 3.2E-32 T 11-10-2018 TO73_1934 2293f8edb604ed975dc595e526737701 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.1E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1934 2293f8edb604ed975dc595e526737701 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 3.1E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1934 2293f8edb604ed975dc595e526737701 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 3.1E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1934 2293f8edb604ed975dc595e526737701 229 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 3 228 4.8E-45 T 11-10-2018 TO73_1934 2293f8edb604ed975dc595e526737701 229 Gene3D G3DSA:3.40.50.720 1 228 2.7E-62 T 11-10-2018 TO73_1934 2293f8edb604ed975dc595e526737701 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.1E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1934 2293f8edb604ed975dc595e526737701 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 213 1.1E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1934 2293f8edb604ed975dc595e526737701 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.1E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1934 2293f8edb604ed975dc595e526737701 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.1E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1934 2293f8edb604ed975dc595e526737701 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.1E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1934 2293f8edb604ed975dc595e526737701 229 SUPERFAMILY SSF51735 1 229 4.71E-61 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 Pfam PF00773 RNB domain 226 545 1.6E-110 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 Hamap MF_01895 Ribonuclease R [rnr]. 18 674 51.565 T 11-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 SUPERFAMILY SSF46785 2 53 6.98E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 56 671 5.1E-143 T 11-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 SMART SM00316 595 674 2.2E-5 T 11-10-2018 IPR022967 RNA-binding domain, S1 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 SUPERFAMILY SSF50249 597 672 1.4E-12 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 Pfam PF00575 S1 RNA binding domain 596 669 2.0E-6 T 11-10-2018 IPR003029 S1 domain GO:0003676 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 SMART SM00357 59 116 0.0066 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 SUPERFAMILY SSF50249 186 591 1.09E-131 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 SUPERFAMILY SSF50249 110 203 4.34E-12 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 ProSitePatterns PS01175 Ribonuclease II family signature. 515 539 - T 11-10-2018 IPR022966 Ribonuclease II/R, conserved site TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 Gene3D G3DSA:2.40.50.140 598 695 7.1E-12 T 11-10-2018 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 Gene3D G3DSA:1.10.10.10 4 54 5.8E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 Pfam PF08206 Ribonuclease B OB domain 60 114 1.7E-8 T 11-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 Gene3D G3DSA:2.40.50.140 55 119 2.5E-8 T 11-10-2018 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 671 1.6E-191 T 11-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 SUPERFAMILY SSF50249 56 118 8.08E-10 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 Pfam PF09339 IclR helix-turn-helix domain 5 48 1.8E-5 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TO73_0718 a4e1225945ca7133e54c8e909b8f9d7f 737 SMART SM00955 226 548 5.9E-153 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TO73_1798 45f7497048ddda096a2f014337bdfe54 348 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 40 341 2.5E-33 T 11-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TO73_1798 45f7497048ddda096a2f014337bdfe54 348 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 171 188 - T 11-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TO73_1798 45f7497048ddda096a2f014337bdfe54 348 PIRSF PIRSF000808 33 348 2.7E-93 T 11-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TO73_1798 45f7497048ddda096a2f014337bdfe54 348 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 225 348 1.4E-10 T 11-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TO73_1798 45f7497048ddda096a2f014337bdfe54 348 SUPERFAMILY SSF54197 37 197 5.48E-48 T 11-10-2018 IPR036265 HIT-like superfamily TO73_1798 45f7497048ddda096a2f014337bdfe54 348 Gene3D G3DSA:3.30.428.10 43 345 1.3E-78 T 11-10-2018 IPR036265 HIT-like superfamily TO73_1798 45f7497048ddda096a2f014337bdfe54 348 Gene3D G3DSA:3.30.428.10 71 195 1.3E-78 T 11-10-2018 IPR036265 HIT-like superfamily TO73_1798 45f7497048ddda096a2f014337bdfe54 348 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 40 196 1.4E-26 T 11-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TO73_1798 45f7497048ddda096a2f014337bdfe54 348 SUPERFAMILY SSF54197 222 347 2.47E-28 T 11-10-2018 IPR036265 HIT-like superfamily TO73_0409 aa2f0120a631ac98693d5f7e16376055 178 Pfam PF14279 HNH endonuclease 94 146 4.7E-17 T 11-10-2018 IPR029471 HNH endonuclease 5 TO73_0409 aa2f0120a631ac98693d5f7e16376055 178 SMART SM00507 81 132 9.6E-16 T 11-10-2018 IPR003615 HNH nuclease TO73_0409 aa2f0120a631ac98693d5f7e16376055 178 Gene3D G3DSA:3.30.40.60 67 154 7.5E-24 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 5.0E-39 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 5.0E-39 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.0E-39 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 5.0E-39 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 5.0E-39 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 Gene3D G3DSA:3.30.390.30 335 455 9.4E-48 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 317 4.4E-75 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 SUPERFAMILY SSF55424 333 454 2.58E-41 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 Gene3D G3DSA:3.50.50.60 142 260 2.7E-131 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0156 5be03d077b32692d5847e0dde7af6102 455 Gene3D G3DSA:3.50.50.60 2 320 2.7E-131 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0156 5be03d077b32692d5847e0dde7af6102 455 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 2 454 1.8E-164 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 SUPERFAMILY SSF51905 2 354 8.37E-69 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 332 353 1.8E-74 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 397 412 1.8E-74 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 1.8E-74 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 419 439 1.8E-74 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 1.8E-74 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.8E-74 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 1.8E-74 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 1.8E-74 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 1.8E-74 T 11-10-2018 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 PIRSF PIRSF000350 1 453 8.4E-96 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TO73_0156 5be03d077b32692d5847e0dde7af6102 455 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 336 445 6.2E-37 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 Pfam PF13365 Trypsin-like peptidase domain 56 198 1.2E-20 T 11-10-2018 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 Pfam PF13180 PDZ domain 237 341 3.2E-15 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 PRINTS PR00834 HtrA/DegQ protease family signature 292 304 2.0E-21 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 PRINTS PR00834 HtrA/DegQ protease family signature 85 105 2.0E-21 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 PRINTS PR00834 HtrA/DegQ protease family signature 128 152 2.0E-21 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 PRINTS PR00834 HtrA/DegQ protease family signature 169 186 2.0E-21 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 PRINTS PR00834 HtrA/DegQ protease family signature 191 208 2.0E-21 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 PRINTS PR00834 HtrA/DegQ protease family signature 64 76 2.0E-21 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 SUPERFAMILY SSF50494 8 245 3.07E-41 T 11-10-2018 IPR009003 Peptidase S1, PA clan TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 Gene3D G3DSA:2.40.10.10 24 114 8.1E-21 T 11-10-2018 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 Gene3D G3DSA:2.40.10.10 121 241 2.1E-15 T 11-10-2018 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 SMART SM00228 237 334 1.4E-13 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 SUPERFAMILY SSF50156 221 341 6.31E-18 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 TO73_1515 fa85559b821f76d0bfc1e559d2cd98ef 349 Gene3D G3DSA:2.30.42.10 244 349 1.5E-25 T 11-10-2018 TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 SUPERFAMILY SSF54184 158 219 1.05E-5 T 11-10-2018 TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 SMART SM00740 220 286 2.2E-8 T 11-10-2018 IPR005543 PASTA domain TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 SMART SM00740 290 355 7.8E-8 T 11-10-2018 IPR005543 PASTA domain TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 SMART SM00740 154 219 8.1E-11 T 11-10-2018 IPR005543 PASTA domain TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 Gene3D G3DSA:3.30.10.20 222 289 4.7E-13 T 11-10-2018 TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 Gene3D G3DSA:3.30.10.20 156 221 1.9E-14 T 11-10-2018 TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 Pfam PF03793 PASTA domain 159 219 2.3E-12 T 11-10-2018 IPR005543 PASTA domain TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 Pfam PF03793 PASTA domain 294 353 1.4E-10 T 11-10-2018 IPR005543 PASTA domain TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 Pfam PF03793 PASTA domain 226 285 5.3E-10 T 11-10-2018 IPR005543 PASTA domain TO73_2070 29dc7a553f8e5fc4de188b227a446a80 438 Gene3D G3DSA:3.30.10.20 294 354 5.8E-12 T 11-10-2018 TO73_1724 2e2cba2ac38a45117a1389888122c65f 242 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 1.2E-79 T 11-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 TO73_1724 2e2cba2ac38a45117a1389888122c65f 242 Pfam PF00005 ABC transporter 20 166 1.6E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1724 2e2cba2ac38a45117a1389888122c65f 242 Gene3D G3DSA:3.40.50.300 1 229 2.2E-66 T 11-10-2018 TO73_1724 2e2cba2ac38a45117a1389888122c65f 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1724 2e2cba2ac38a45117a1389888122c65f 242 SMART SM00382 28 215 1.9E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1724 2e2cba2ac38a45117a1389888122c65f 242 SUPERFAMILY SSF52540 2 223 2.6E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0223 c9e148c2f4c9b4440f6deacafd431741 368 SUPERFAMILY SSF52540 14 347 2.47E-74 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0223 c9e148c2f4c9b4440f6deacafd431741 368 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 203 217 - T 11-10-2018 IPR001482 Type II/IV secretion system protein TO73_0223 c9e148c2f4c9b4440f6deacafd431741 368 Gene3D G3DSA:3.40.50.300 110 367 4.5E-94 T 11-10-2018 TO73_0223 c9e148c2f4c9b4440f6deacafd431741 368 SMART SM00382 132 257 0.0029 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0223 c9e148c2f4c9b4440f6deacafd431741 368 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 12 355 3.4E-153 T 11-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 TO73_0223 c9e148c2f4c9b4440f6deacafd431741 368 Pfam PF00437 Type II/IV secretion system protein 17 266 2.5E-43 T 11-10-2018 IPR001482 Type II/IV secretion system protein TO73_0223 c9e148c2f4c9b4440f6deacafd431741 368 Gene3D G3DSA:3.30.450.90 1 109 2.4E-41 T 11-10-2018 TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 SMART SM00100 5 123 4.7E-18 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 73 90 - T 11-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 Gene3D G3DSA:1.10.10.10 139 215 2.3E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 Gene3D G3DSA:2.60.120.10 3 138 9.5E-46 T 11-10-2018 IPR014710 RmlC-like jelly roll fold TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 SUPERFAMILY SSF51206 4 130 2.62E-34 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 SUPERFAMILY SSF46785 141 211 3.26E-13 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 Pfam PF13545 Crp-like helix-turn-helix domain 144 209 1.7E-13 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 PRINTS PR00103 cAMP-dependent protein kinase signature 41 55 6.6E-5 T 11-10-2018 TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 PRINTS PR00103 cAMP-dependent protein kinase signature 71 80 6.6E-5 T 11-10-2018 TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 PRINTS PR00103 cAMP-dependent protein kinase signature 83 94 6.6E-5 T 11-10-2018 TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 PRINTS PR00103 cAMP-dependent protein kinase signature 26 40 6.6E-5 T 11-10-2018 TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 Pfam PF00027 Cyclic nucleotide-binding domain 24 109 3.2E-22 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain TO73_0632 a84b8ceb4772af33ceb3d216e4e02abc 215 SMART SM00419 155 203 4.3E-5 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_0513 06ea644d177ae2788c1a8949804b2415 138 SUPERFAMILY SSF52833 6 132 1.33E-29 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_0513 06ea644d177ae2788c1a8949804b2415 138 SMART SM00594 11 126 6.6E-4 T 11-10-2018 IPR006577 UAS TO73_0513 06ea644d177ae2788c1a8949804b2415 138 Gene3D G3DSA:3.40.30.10 18 136 2.4E-28 T 11-10-2018 TO73_0513 06ea644d177ae2788c1a8949804b2415 138 Pfam PF13098 Thioredoxin-like domain 29 124 5.7E-12 T 11-10-2018 IPR012336 Thioredoxin-like fold TO73_1777 ff2c78f2a65c5e85b1c44dba41ddf2b8 437 Gene3D G3DSA:3.40.640.10 79 340 2.5E-152 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1777 ff2c78f2a65c5e85b1c44dba41ddf2b8 437 Pfam PF02347 Glycine cleavage system P-protein 3 396 9.0E-115 T 11-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TO73_1777 ff2c78f2a65c5e85b1c44dba41ddf2b8 437 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 1 436 42.376 T 11-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TO73_1777 ff2c78f2a65c5e85b1c44dba41ddf2b8 437 SUPERFAMILY SSF53383 1 437 3.88E-110 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1777 ff2c78f2a65c5e85b1c44dba41ddf2b8 437 Gene3D G3DSA:3.90.1150.10 68 433 2.5E-152 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1777 ff2c78f2a65c5e85b1c44dba41ddf2b8 437 PIRSF PIRSF006815 1 437 4.3E-152 T 11-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TO73_1127 c00201e4fa1776b2ad17bfe2f21ec05d 251 Pfam PF13277 YmdB-like protein 4 236 1.5E-86 T 11-10-2018 IPR005235 Metallophosphoesterase, YmdB-like TO73_1127 c00201e4fa1776b2ad17bfe2f21ec05d 251 Gene3D G3DSA:3.60.21.10 1 251 8.9E-102 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like TO73_1127 c00201e4fa1776b2ad17bfe2f21ec05d 251 PIRSF PIRSF004789 1 250 2.2E-78 T 11-10-2018 IPR005235 Metallophosphoesterase, YmdB-like TO73_1127 c00201e4fa1776b2ad17bfe2f21ec05d 251 SUPERFAMILY SSF56300 1 231 3.31E-74 T 11-10-2018 TO73_1127 c00201e4fa1776b2ad17bfe2f21ec05d 251 SMART SM00854 2 178 0.008 T 11-10-2018 IPR019079 Capsule synthesis protein, CapA TO73_2089 b783e1a251b8542816feae1efcc584a4 615 PIRSF PIRSF002741 18 197 1.9E-9 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TO73_2089 b783e1a251b8542816feae1efcc584a4 615 PIRSF PIRSF002741 207 593 2.1E-43 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TO73_2089 b783e1a251b8542816feae1efcc584a4 615 Gene3D G3DSA:3.10.105.10 327 567 9.6E-263 T 11-10-2018 TO73_2089 b783e1a251b8542816feae1efcc584a4 615 Gene3D G3DSA:3.40.190.10 21 603 9.6E-263 T 11-10-2018 TO73_2089 b783e1a251b8542816feae1efcc584a4 615 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 490 8.0E-51 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain TO73_2089 b783e1a251b8542816feae1efcc584a4 615 SUPERFAMILY SSF53850 21 592 8.69E-80 T 11-10-2018 TO73_2089 b783e1a251b8542816feae1efcc584a4 615 Gene3D G3DSA:3.90.76.10 65 181 9.6E-263 T 11-10-2018 TO73_1388 bbd4b6c69525c68735eb8273a2b02f79 962 SUPERFAMILY SSF52540 5 950 1.12E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1388 bbd4b6c69525c68735eb8273a2b02f79 962 Gene3D G3DSA:3.40.50.300 2 279 4.3E-48 T 11-10-2018 TO73_1388 bbd4b6c69525c68735eb8273a2b02f79 962 Gene3D G3DSA:3.40.50.300 717 961 9.6E-30 T 11-10-2018 TO73_1388 bbd4b6c69525c68735eb8273a2b02f79 962 Pfam PF13476 AAA domain 5 255 6.7E-19 T 11-10-2018 IPR038729 Rad50/SbcC-type AAA domain TO73_1388 bbd4b6c69525c68735eb8273a2b02f79 962 Pfam PF13558 Putative exonuclease SbcCD, C subunit 862 922 1.6E-10 T 11-10-2018 TO73_1860 da8092e161d316ee62824c4b9155b01a 208 SMART SM00116 78 125 5.1E-11 T 11-10-2018 IPR000644 CBS domain TO73_1860 da8092e161d316ee62824c4b9155b01a 208 SMART SM00116 10 57 1.6E-12 T 11-10-2018 IPR000644 CBS domain TO73_1860 da8092e161d316ee62824c4b9155b01a 208 Pfam PF00571 CBS domain 3 55 1.3E-16 T 11-10-2018 IPR000644 CBS domain TO73_1860 da8092e161d316ee62824c4b9155b01a 208 Pfam PF00571 CBS domain 71 125 2.4E-13 T 11-10-2018 IPR000644 CBS domain TO73_1860 da8092e161d316ee62824c4b9155b01a 208 Pfam PF01842 ACT domain 136 183 1.0E-8 T 11-10-2018 IPR002912 ACT domain TO73_1860 da8092e161d316ee62824c4b9155b01a 208 SUPERFAMILY SSF55021 137 201 3.88E-8 T 11-10-2018 TO73_1860 da8092e161d316ee62824c4b9155b01a 208 Gene3D G3DSA:3.10.580.10 1 143 1.8E-38 T 11-10-2018 TO73_1860 da8092e161d316ee62824c4b9155b01a 208 SUPERFAMILY SSF54631 1 127 1.77E-34 T 11-10-2018 TO73_1154 29b17f9a502a2bc9b5e2e6349c77d941 124 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 121 7.0E-36 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TO73_1154 29b17f9a502a2bc9b5e2e6349c77d941 124 SUPERFAMILY SSF81330 10 116 7.32E-31 T 11-10-2018 IPR036019 Gated mechanosensitive channel TO73_1154 29b17f9a502a2bc9b5e2e6349c77d941 124 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 122 22.919 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TO73_1154 29b17f9a502a2bc9b5e2e6349c77d941 124 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 120 8.7E-40 T 11-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L TO73_1154 29b17f9a502a2bc9b5e2e6349c77d941 124 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 11-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site TO73_1154 29b17f9a502a2bc9b5e2e6349c77d941 124 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.1E-9 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TO73_1154 29b17f9a502a2bc9b5e2e6349c77d941 124 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 81 90 1.1E-9 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TO73_1154 29b17f9a502a2bc9b5e2e6349c77d941 124 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 71 79 1.1E-9 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TO73_1154 29b17f9a502a2bc9b5e2e6349c77d941 124 Gene3D G3DSA:1.10.1200.120 1 124 2.5E-39 T 11-10-2018 IPR036019 Gated mechanosensitive channel TO73_0557 32a253b4d111846e50baa9da579b892a 207 Gene3D G3DSA:3.30.70.2830 94 207 2.1E-45 T 11-10-2018 TO73_2384 a09fc8c102967898b38bf29894f70b3d 175 SUPERFAMILY SSF50324 4 173 1.15E-61 T 11-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TO73_2384 a09fc8c102967898b38bf29894f70b3d 175 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 11-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TO73_2384 a09fc8c102967898b38bf29894f70b3d 175 Pfam PF00719 Inorganic pyrophosphatase 19 173 6.1E-53 T 11-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TO73_2384 a09fc8c102967898b38bf29894f70b3d 175 Gene3D G3DSA:3.90.80.10 2 174 3.4E-71 T 11-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TO73_2384 a09fc8c102967898b38bf29894f70b3d 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 174 36.288 T 11-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TO73_1953 037f7cf4ec604cc1f684ce111e48281d 144 SUPERFAMILY SSF54631 1 142 8.46E-32 T 11-10-2018 TO73_1953 037f7cf4ec604cc1f684ce111e48281d 144 SMART SM00116 4 52 2.2E-4 T 11-10-2018 IPR000644 CBS domain TO73_1953 037f7cf4ec604cc1f684ce111e48281d 144 SMART SM00116 93 141 8.1E-12 T 11-10-2018 IPR000644 CBS domain TO73_1953 037f7cf4ec604cc1f684ce111e48281d 144 Pfam PF00571 CBS domain 86 141 5.8E-15 T 11-10-2018 IPR000644 CBS domain TO73_1953 037f7cf4ec604cc1f684ce111e48281d 144 Pfam PF00571 CBS domain 1 42 2.6E-9 T 11-10-2018 IPR000644 CBS domain TO73_1953 037f7cf4ec604cc1f684ce111e48281d 144 Gene3D G3DSA:3.10.580.10 1 144 1.9E-32 T 11-10-2018 TO73_0248 a431f53ce1fb077a0d101260dccad756 161 Gene3D G3DSA:3.40.30.10 16 158 2.0E-35 T 11-10-2018 TO73_0248 a431f53ce1fb077a0d101260dccad756 161 SUPERFAMILY SSF52833 19 153 2.67E-28 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_0248 a431f53ce1fb077a0d101260dccad756 161 Pfam PF00578 AhpC/TSA family 22 136 1.2E-15 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TO73_0527 759beca9f25d15390958f875e70529f6 142 Pfam PF03100 CcmE 2 125 3.0E-39 T 11-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 TO73_0527 759beca9f25d15390958f875e70529f6 142 SUPERFAMILY SSF82093 24 126 1.01E-33 T 11-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 TO73_0527 759beca9f25d15390958f875e70529f6 142 Gene3D G3DSA:2.40.50.140 24 129 2.1E-33 T 11-10-2018 TO73_0527 759beca9f25d15390958f875e70529f6 142 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 138 25.409 T 11-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 30 572 4.1E-157 T 11-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 390 431 9.7E-6 T 11-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 PIRSF PIRSF004803 22 575 7.8E-220 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 SMART SM00849 42 244 6.5E-15 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 Pfam PF12706 Beta-lactamase superfamily domain 83 195 8.3E-12 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 Gene3D G3DSA:3.60.15.10 32 472 5.8E-177 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 Gene3D G3DSA:3.40.50.10710 237 386 5.8E-177 T 11-10-2018 TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 Hamap MF_01491 Ribonuclease J [rnj]. 25 575 41.416 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 SUPERFAMILY SSF56281 31 452 1.12E-83 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_0733 d656d458d900f2b66e376cde54cbbdb9 575 Gene3D G3DSA:3.10.20.580 477 574 1.3E-38 T 11-10-2018 TO73_1085 ed6b028042999f88efc98234ed464de2 170 SUPERFAMILY SSF53335 1 167 7.19E-39 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1085 ed6b028042999f88efc98234ed464de2 170 Pfam PF03602 Conserved hypothetical protein 95 1 153 2.8E-30 T 11-10-2018 TO73_1085 ed6b028042999f88efc98234ed464de2 170 PIRSF PIRSF004553 1 170 6.1E-34 T 11-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 TO73_1085 ed6b028042999f88efc98234ed464de2 170 Gene3D G3DSA:3.40.50.150 1 170 4.3E-48 T 11-10-2018 TO73_0414 688d371fb4d6f9978c14839811fb5082 315 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 77 91 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site TO73_0414 688d371fb4d6f9978c14839811fb5082 315 Pfam PF00348 Polyprenyl synthetase 34 255 2.7E-62 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TO73_0414 688d371fb4d6f9978c14839811fb5082 315 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 199 211 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site TO73_0414 688d371fb4d6f9978c14839811fb5082 315 SUPERFAMILY SSF48576 14 313 8.49E-77 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily TO73_0414 688d371fb4d6f9978c14839811fb5082 315 Gene3D G3DSA:1.10.600.10 5 313 2.2E-87 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily TO73_1323 2b893d6495f373f08b738a60db046a98 233 Gene3D G3DSA:2.40.160.70 30 233 7.4E-71 T 11-10-2018 TO73_2378 7e91d8a07a1a7e9df509607e3294b2f2 352 SUPERFAMILY SSF55681 88 349 5.45E-74 T 11-10-2018 TO73_2378 7e91d8a07a1a7e9df509607e3294b2f2 352 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 4 348 45.16 T 11-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 TO73_2378 7e91d8a07a1a7e9df509607e3294b2f2 352 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 35 348 2.3E-91 T 11-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TO73_2378 7e91d8a07a1a7e9df509607e3294b2f2 352 SUPERFAMILY SSF46589 8 94 7.85E-20 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TO73_2378 7e91d8a07a1a7e9df509607e3294b2f2 352 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 15 83 5.8E-20 T 11-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TO73_2378 7e91d8a07a1a7e9df509607e3294b2f2 352 Gene3D G3DSA:3.30.930.10 3 352 4.8E-121 T 11-10-2018 TO73_2378 7e91d8a07a1a7e9df509607e3294b2f2 352 Pfam PF01409 tRNA synthetases class II core domain (F) 88 348 9.2E-96 T 11-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TO73_2791 5172399c4a24fce5a34f70918dab4605 251 Gene3D G3DSA:1.10.10.10 115 181 4.0E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2791 5172399c4a24fce5a34f70918dab4605 251 SUPERFAMILY SSF88659 116 175 2.05E-11 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TO73_2791 5172399c4a24fce5a34f70918dab4605 251 Pfam PF04539 Sigma-70 region 3 119 180 4.2E-13 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TO73_0652 ed8a12d9aec38df6c7e811158c712e8a 195 SMART SM00393 105 184 4.0E-21 T 11-10-2018 IPR001374 R3H domain GO:0003676 TO73_0652 ed8a12d9aec38df6c7e811158c712e8a 195 Gene3D G3DSA:3.30.300.20 33 119 2.5E-16 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_0652 ed8a12d9aec38df6c7e811158c712e8a 195 SUPERFAMILY SSF82708 140 184 1.47E-9 T 11-10-2018 IPR036867 R3H domain superfamily GO:0003676 TO73_0652 ed8a12d9aec38df6c7e811158c712e8a 195 Gene3D G3DSA:3.30.1370.50 120 192 1.6E-23 T 11-10-2018 IPR036867 R3H domain superfamily GO:0003676 TO73_0652 ed8a12d9aec38df6c7e811158c712e8a 195 Pfam PF13083 KH domain 42 110 3.4E-9 T 11-10-2018 TO73_0652 ed8a12d9aec38df6c7e811158c712e8a 195 Pfam PF01424 R3H domain 125 183 3.8E-15 T 11-10-2018 IPR001374 R3H domain GO:0003676 TO73_0571 d825e6d70b2ddcfc14f32d7bf5219900 250 Gene3D G3DSA:3.40.1090.10 1 84 3.5E-26 T 11-10-2018 TO73_0571 d825e6d70b2ddcfc14f32d7bf5219900 250 Gene3D G3DSA:3.40.1090.10 85 215 7.1E-21 T 11-10-2018 TO73_0571 d825e6d70b2ddcfc14f32d7bf5219900 250 Pfam PF01734 Patatin-like phospholipase 4 159 2.6E-25 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 TO73_0571 d825e6d70b2ddcfc14f32d7bf5219900 250 SUPERFAMILY SSF52151 2 245 3.66E-53 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TO73_2815 e43a659a8a32ebe3a564ac585ddd5738 138 Gene3D G3DSA:3.40.50.1010 2 137 1.8E-40 T 11-10-2018 TO73_2815 e43a659a8a32ebe3a564ac585ddd5738 138 SUPERFAMILY SSF88723 3 136 3.92E-31 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_2815 e43a659a8a32ebe3a564ac585ddd5738 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 135 11.799 T 11-10-2018 IPR022907 VapC family GO:0004540 TO73_2815 e43a659a8a32ebe3a564ac585ddd5738 138 Pfam PF01850 PIN domain 3 123 1.4E-15 T 11-10-2018 IPR002716 PIN domain TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 SUPERFAMILY SSF46977 434 569 1.7E-51 T 11-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 1 569 2.1E-282 T 11-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 SUPERFAMILY SSF56425 224 342 4.49E-42 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 PIRSF PIRSF000171 1 562 5.5E-48 T 11-10-2018 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 Pfam PF00890 FAD binding domain 1 389 4.7E-113 T 11-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 Gene3D G3DSA:1.20.58.100 416 530 3.0E-37 T 11-10-2018 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 1 569 7.4E-243 T 11-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 32 41 - T 11-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 Gene3D G3DSA:3.90.700.10 234 337 1.1E-160 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 Pfam PF02910 Fumarate reductase flavoprotein C-term 443 569 1.4E-42 T 11-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 Gene3D G3DSA:3.50.50.60 1 400 1.1E-160 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 Gene3D G3DSA:4.10.80.40 531 565 3.4E-7 T 11-10-2018 TO73_1536 944b2e1e35436cb941a68d3d5fd4ceae 569 SUPERFAMILY SSF51905 1 412 2.46E-74 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 Pfam PF00366 Ribosomal protein S17 8 74 1.1E-32 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 78 24.276 T 11-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 3 74 2.0E-33 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 3 73 4.9E-35 T 11-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 PRINTS PR00973 Ribosomal protein S17 family signature 64 71 5.1E-12 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 PRINTS PR00973 Ribosomal protein S17 family signature 22 45 5.1E-12 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 PRINTS PR00973 Ribosomal protein S17 family signature 54 64 5.1E-12 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 Gene3D G3DSA:2.40.50.140 2 105 1.3E-47 T 11-10-2018 TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 ProSitePatterns PS00056 Ribosomal protein S17 signature. 54 66 - T 11-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0385 ae4578946bcf334ffe71fac5774f4ee1 105 SUPERFAMILY SSF50249 3 100 3.71E-33 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1804 a3e83dffdd556274a0521b8e71dd449c 307 SUPERFAMILY SSF53271 86 279 7.0E-44 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_1804 a3e83dffdd556274a0521b8e71dd449c 307 Gene3D G3DSA:3.40.50.2020 6 295 6.3E-110 T 11-10-2018 TO73_1804 a3e83dffdd556274a0521b8e71dd449c 307 Pfam PF00156 Phosphoribosyl transferase domain 150 247 5.7E-13 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TO73_1804 a3e83dffdd556274a0521b8e71dd449c 307 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 306 3.1E-106 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TO73_1804 a3e83dffdd556274a0521b8e71dd449c 307 SMART SM01400 3 119 7.3E-77 T 11-10-2018 TO73_1804 a3e83dffdd556274a0521b8e71dd449c 307 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 119 2.6E-46 T 11-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TO73_1804 a3e83dffdd556274a0521b8e71dd449c 307 Gene3D G3DSA:3.40.50.2020 146 284 6.3E-110 T 11-10-2018 TO73_1804 a3e83dffdd556274a0521b8e71dd449c 307 SUPERFAMILY SSF53271 4 156 3.15E-54 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_1804 a3e83dffdd556274a0521b8e71dd449c 307 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 127 142 - T 11-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TO73_1899 2a5eeb29cd6318503ad9efeed8fa3f59 377 SUPERFAMILY SSF103473 9 374 2.22E-36 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_1899 2a5eeb29cd6318503ad9efeed8fa3f59 377 Gene3D G3DSA:1.20.1250.20 190 376 8.4E-14 T 11-10-2018 TO73_1899 2a5eeb29cd6318503ad9efeed8fa3f59 377 Gene3D G3DSA:1.20.1250.20 8 189 2.0E-11 T 11-10-2018 TO73_1899 2a5eeb29cd6318503ad9efeed8fa3f59 377 Pfam PF07690 Major Facilitator Superfamily 11 316 2.0E-21 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_0724 9c174cbb61a21005a6f28a04d2530743 179 SMART SM01207 5 177 5.1E-41 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_0724 9c174cbb61a21005a6f28a04d2530743 179 Pfam PF02660 Glycerol-3-phosphate acyltransferase 6 178 4.0E-37 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_0724 9c174cbb61a21005a6f28a04d2530743 179 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 2 168 13.351 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_2162 877579043722a0d59aec1a69694f5904 616 Gene3D G3DSA:3.40.50.920 499 602 9.5E-21 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_2162 877579043722a0d59aec1a69694f5904 616 SUPERFAMILY SSF52922 500 602 1.57E-15 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_2162 877579043722a0d59aec1a69694f5904 616 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 243 474 4.5E-60 T 11-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TO73_2162 877579043722a0d59aec1a69694f5904 616 SUPERFAMILY SSF52518 231 490 2.29E-58 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_2162 877579043722a0d59aec1a69694f5904 616 Gene3D G3DSA:3.40.920.10 2 218 3.1E-16 T 11-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TO73_2162 877579043722a0d59aec1a69694f5904 616 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 508 593 1.0E-6 T 11-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TO73_2162 877579043722a0d59aec1a69694f5904 616 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 3 597 1.8E-174 T 11-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 TO73_2162 877579043722a0d59aec1a69694f5904 616 SUPERFAMILY SSF53323 4 249 3.27E-17 T 11-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TO73_2162 877579043722a0d59aec1a69694f5904 616 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 211 7.8E-40 T 11-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TO73_2162 877579043722a0d59aec1a69694f5904 616 Gene3D G3DSA:3.40.50.970 223 417 3.5E-66 T 11-10-2018 TO73_2375 17d89a65da529bb0db667b29a48a0ed4 706 Gene3D G3DSA:3.40.50.300 247 370 1.7E-5 T 11-10-2018 TO73_2375 17d89a65da529bb0db667b29a48a0ed4 706 Hamap MF_00983 Probable primosomal protein N' [priA]. 5 700 17.218 T 11-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 TO73_2375 17d89a65da529bb0db667b29a48a0ed4 706 Gene3D G3DSA:1.10.8.630 3 108 1.6E-12 T 11-10-2018 TO73_1788 316da0d3b79b43d3e135c44e405ac9d2 368 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 347 42.444 T 11-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TO73_1788 316da0d3b79b43d3e135c44e405ac9d2 368 SUPERFAMILY SSF51246 300 361 1.1E-17 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TO73_1788 316da0d3b79b43d3e135c44e405ac9d2 368 Gene3D G3DSA:3.30.470.20 176 366 2.7E-78 T 11-10-2018 TO73_1788 316da0d3b79b43d3e135c44e405ac9d2 368 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 3 352 3.1E-113 T 11-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TO73_1788 316da0d3b79b43d3e135c44e405ac9d2 368 Pfam PF02222 ATP-grasp domain 108 275 1.4E-53 T 11-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TO73_1788 316da0d3b79b43d3e135c44e405ac9d2 368 Gene3D G3DSA:3.30.1490.20 97 175 1.8E-24 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TO73_1788 316da0d3b79b43d3e135c44e405ac9d2 368 SUPERFAMILY SSF52440 2 94 2.3E-20 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TO73_1788 316da0d3b79b43d3e135c44e405ac9d2 368 Gene3D G3DSA:3.40.50.20 2 96 1.4E-31 T 11-10-2018 TO73_1788 316da0d3b79b43d3e135c44e405ac9d2 368 SUPERFAMILY SSF56059 97 295 3.36E-64 T 11-10-2018 TO73_1787 780139114a696745270fae69256fc37f 156 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 150 8.1E-65 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TO73_1787 780139114a696745270fae69256fc37f 156 Pfam PF00731 AIR carboxylase 1 144 2.0E-62 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TO73_1787 780139114a696745270fae69256fc37f 156 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 150 30.004 T 11-10-2018 IPR033747 Class I PurE TO73_1787 780139114a696745270fae69256fc37f 156 SUPERFAMILY SSF52255 1 154 1.7E-63 T 11-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TO73_1787 780139114a696745270fae69256fc37f 156 PIRSF PIRSF001338 1 155 8.9E-63 T 11-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 TO73_1787 780139114a696745270fae69256fc37f 156 Gene3D G3DSA:3.40.50.7700 1 156 1.0E-70 T 11-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TO73_1787 780139114a696745270fae69256fc37f 156 SMART SM01001 1 146 2.2E-93 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TO73_1004 8fc3ea371fd31c8c0431df92718792ab 246 Gene3D G3DSA:3.90.850.10 41 246 1.1E-76 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TO73_1004 8fc3ea371fd31c8c0431df92718792ab 246 Gene3D G3DSA:2.30.30.370 1 40 1.9E-21 T 11-10-2018 TO73_1004 8fc3ea371fd31c8c0431df92718792ab 246 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 245 7.7E-119 T 11-10-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 TO73_1004 8fc3ea371fd31c8c0431df92718792ab 246 SUPERFAMILY SSF56529 36 244 7.98E-73 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TO73_1004 8fc3ea371fd31c8c0431df92718792ab 246 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 46 242 1.5E-62 T 11-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TO73_1701 9e539a1f08e0341f05da4ab59819b7fd 229 Gene3D G3DSA:3.40.30.10 1 124 8.5E-29 T 11-10-2018 TO73_1701 9e539a1f08e0341f05da4ab59819b7fd 229 Pfam PF13192 Thioredoxin domain 146 221 9.2E-15 T 11-10-2018 IPR012336 Thioredoxin-like fold TO73_1701 9e539a1f08e0341f05da4ab59819b7fd 229 SUPERFAMILY SSF52833 131 223 8.73E-19 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1701 9e539a1f08e0341f05da4ab59819b7fd 229 Gene3D G3DSA:3.40.30.10 130 223 3.4E-26 T 11-10-2018 TO73_1701 9e539a1f08e0341f05da4ab59819b7fd 229 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 5 224 3.5E-89 T 11-10-2018 IPR011903 Glutaredoxin-like domain TO73_1701 9e539a1f08e0341f05da4ab59819b7fd 229 SUPERFAMILY SSF52833 4 125 7.14E-19 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 Pfam PF04898 Glutamate synthase central domain 450 725 3.8E-61 T 11-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 Gene3D G3DSA:2.160.20.60 1204 1492 6.1E-64 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 Pfam PF01493 GXGXG motif 1373 1407 4.3E-5 T 11-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 Pfam PF01493 GXGXG motif 1227 1353 8.3E-18 T 11-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 Pfam PF01645 Conserved region in glutamate synthase 789 1149 4.2E-108 T 11-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 Gene3D G3DSA:3.20.20.70 472 1166 0.0 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 SUPERFAMILY SSF69336 1201 1488 6.8E-45 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 SUPERFAMILY SSF56235 17 385 1.4E-76 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 Gene3D G3DSA:3.20.20.70 414 771 0.0 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 Pfam PF00310 Glutamine amidotransferases class-II 17 384 2.5E-43 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 Gene3D G3DSA:3.60.20.10 17 532 0.0 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_1958 e80cb9bc946a3b90bebf12f33c66a24c 1492 SUPERFAMILY SSF51395 459 1167 1.71E-167 T 11-10-2018 TO73_2503 fbf118fc15891b1c920fb0fbf5e2dbce 120 Pfam PF01927 Mut7-C RNAse domain 6 91 6.5E-7 T 11-10-2018 IPR002782 Mut7-C RNAse domain TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 4.2E-40 T 11-10-2018 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 4.2E-40 T 11-10-2018 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 4.2E-40 T 11-10-2018 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 4.2E-40 T 11-10-2018 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 4.2E-40 T 11-10-2018 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 4.7E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 118 126 4.7E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 207 223 4.7E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 4.7E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 245 266 4.7E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 73 83 4.7E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 297 4.7E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 152 4.7E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 52 67 4.7E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 147 167 - T 11-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 18 305 4.3E-52 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 Gene3D G3DSA:3.50.50.60 18 308 4.6E-124 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 Gene3D G3DSA:3.50.50.60 129 251 4.6E-124 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 316 3.5E-119 T 11-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 TO73_2307 4c151f8ad2237172b7e5e09f4e5537c1 325 SUPERFAMILY SSF51905 15 316 4.94E-59 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 458 2.0E-210 T 11-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 SUPERFAMILY SSF48557 3 458 6.13E-156 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 Pfam PF10415 Fumarase C C-terminus 408 460 9.5E-22 T 11-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 Pfam PF00206 Lyase 11 342 3.7E-110 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 Gene3D G3DSA:1.20.200.10 139 404 7.5E-114 T 11-10-2018 TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 Gene3D G3DSA:1.10.275.10 1 138 4.5E-64 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 462 89.71 T 11-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 Gene3D G3DSA:1.10.40.30 405 466 9.0E-28 T 11-10-2018 TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 2.5E-32 T 11-10-2018 IPR000362 Fumarate lyase family TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 2.5E-32 T 11-10-2018 IPR000362 Fumarate lyase family TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 2.5E-32 T 11-10-2018 IPR000362 Fumarate lyase family TO73_1346 5d8efc92cf97029fca88560c37ba912f 466 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 2.5E-32 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 128 575 1.3E-192 T 11-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 Pfam PF00013 KH domain 268 322 3.6E-6 T 11-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 TIGRFAM TIGR00277 HDIG: HDIG domain 387 462 1.7E-24 T 11-10-2018 IPR006675 HDIG domain TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 SMART SM00322 263 330 8.2E-7 T 11-10-2018 IPR004087 K Homology domain GO:0003676 TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 Hamap MF_00335 Ribonuclease Y [rny]. 1 575 24.773 T 11-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 Pfam PF12072 Domain of unknown function (DUF3552) 135 259 9.8E-18 T 11-10-2018 IPR022711 Ribonuclease Y, N-terminal TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 SUPERFAMILY SSF54791 268 358 3.99E-15 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 Pfam PF01966 HD domain 392 483 1.7E-18 T 11-10-2018 IPR006674 HD domain TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 Gene3D G3DSA:3.30.1370.10 266 357 6.9E-9 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 SMART SM00471 387 493 3.7E-13 T 11-10-2018 IPR003607 HD/PDEase domain TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 SUPERFAMILY SSF109604 380 503 1.71E-28 T 11-10-2018 TO73_0319 2414b7604cf5a2bd1d8693dc420759b2 575 Gene3D G3DSA:1.10.3210.10 366 527 4.8E-25 T 11-10-2018 TO73_1933 4c42c5c30032fd5866170d54fe0f44e5 121 PRINTS PR00502 NUDIX hydrolase family signature 19 33 6.4E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_1933 4c42c5c30032fd5866170d54fe0f44e5 121 PRINTS PR00502 NUDIX hydrolase family signature 33 48 6.4E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_1933 4c42c5c30032fd5866170d54fe0f44e5 121 Gene3D G3DSA:3.90.79.10 1 121 4.8E-25 T 11-10-2018 TO73_1933 4c42c5c30032fd5866170d54fe0f44e5 121 ProSitePatterns PS00893 Nudix box signature. 24 45 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TO73_1933 4c42c5c30032fd5866170d54fe0f44e5 121 Pfam PF00293 NUDIX domain 3 104 1.9E-20 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TO73_1933 4c42c5c30032fd5866170d54fe0f44e5 121 SUPERFAMILY SSF55811 3 120 1.03E-25 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TO73_0129 3c224dd25b854febe4bc39aa938e88bb 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 2.4E-22 T 11-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0129 3c224dd25b854febe4bc39aa938e88bb 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 25.529 T 11-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0129 3c224dd25b854febe4bc39aa938e88bb 148 SUPERFAMILY SSF55658 1 56 6.63E-18 T 11-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal TO73_0129 3c224dd25b854febe4bc39aa938e88bb 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 1.8E-24 T 11-10-2018 IPR020069 Ribosomal protein L9, C-terminal TO73_0129 3c224dd25b854febe4bc39aa938e88bb 148 Gene3D G3DSA:3.40.5.10 1 59 9.7E-26 T 11-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0129 3c224dd25b854febe4bc39aa938e88bb 148 SUPERFAMILY SSF55653 57 145 3.53E-24 T 11-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TO73_0129 3c224dd25b854febe4bc39aa938e88bb 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 11-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0129 3c224dd25b854febe4bc39aa938e88bb 148 Gene3D G3DSA:3.10.430.100 60 148 9.2E-32 T 11-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TO73_0129 3c224dd25b854febe4bc39aa938e88bb 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 3.0E-41 T 11-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1738 4e66a99c75b8fdc3abfe5920d61583c9 267 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 7 220 30.658 T 11-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TO73_1738 4e66a99c75b8fdc3abfe5920d61583c9 267 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 11 211 9.1E-63 T 11-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TO73_1738 4e66a99c75b8fdc3abfe5920d61583c9 267 Gene3D G3DSA:3.30.1360.170 2 227 2.1E-77 T 11-10-2018 TO73_1738 4e66a99c75b8fdc3abfe5920d61583c9 267 Pfam PF02511 Thymidylate synthase complementing protein 13 206 1.8E-56 T 11-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TO73_1738 4e66a99c75b8fdc3abfe5920d61583c9 267 SUPERFAMILY SSF69796 4 220 5.75E-70 T 11-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TO73_1105 bbe3a72b3d91892301a51f737a9753eb 144 Gene3D G3DSA:2.40.280.10 1 125 3.3E-51 T 11-10-2018 IPR023620 Small protein B TO73_1105 bbe3a72b3d91892301a51f737a9753eb 144 Hamap MF_00023 SsrA-binding protein [smpB]. 1 144 63.594 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 TO73_1105 bbe3a72b3d91892301a51f737a9753eb 144 Pfam PF01668 SmpB protein 5 142 6.9E-56 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 TO73_1105 bbe3a72b3d91892301a51f737a9753eb 144 TIGRFAM TIGR00086 smpB: SsrA-binding protein 5 141 1.2E-52 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 TO73_1105 bbe3a72b3d91892301a51f737a9753eb 144 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 4 122 2.0E-47 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 TO73_1105 bbe3a72b3d91892301a51f737a9753eb 144 ProSitePatterns PS01317 SsrA-binding protein. 22 34 - T 11-10-2018 IPR020081 SsrA-binding protein, conserved site TO73_1105 bbe3a72b3d91892301a51f737a9753eb 144 SUPERFAMILY SSF74982 4 128 5.75E-49 T 11-10-2018 IPR023620 Small protein B TO73_0417 9d4bc4fd25a30bf301d5495fbec61ea7 176 SUPERFAMILY SSF55729 18 154 3.92E-27 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_0417 9d4bc4fd25a30bf301d5495fbec61ea7 176 Pfam PF13302 Acetyltransferase (GNAT) domain 18 149 4.7E-22 T 11-10-2018 IPR000182 GNAT domain TO73_0417 9d4bc4fd25a30bf301d5495fbec61ea7 176 Gene3D G3DSA:3.40.630.30 6 175 8.0E-33 T 11-10-2018 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 SUPERFAMILY SSF50104 127 272 1.68E-59 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 SUPERFAMILY SSF50249 2 125 7.54E-55 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 2.5E-34 T 11-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 127 251 4.1E-54 T 11-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 Gene3D G3DSA:4.10.950.10 197 276 2.8E-36 T 11-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 11-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 SMART SM01383 42 119 2.9E-47 T 11-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 SMART SM01382 125 253 8.5E-85 T 11-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 Gene3D G3DSA:2.40.50.140 1 115 1.9E-53 T 11-10-2018 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 Gene3D G3DSA:2.30.30.30 119 196 4.4E-31 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 PIRSF PIRSF002158 3 276 2.9E-104 T 11-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.847 T 11-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TO73_0379 03c4f67355ebd70cd54e1aca1ab04568 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 1.6E-136 T 11-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TO73_1240 7315915b56c87ba0407a973b6b1ebb70 1061 Gene3D G3DSA:2.40.40.20 897 1031 1.6E-22 T 11-10-2018 TO73_1240 7315915b56c87ba0407a973b6b1ebb70 1061 Gene3D G3DSA:3.40.50.740 592 762 8.2E-16 T 11-10-2018 TO73_1240 7315915b56c87ba0407a973b6b1ebb70 1061 SUPERFAMILY SSF50692 900 1061 6.78E-21 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TO73_1240 7315915b56c87ba0407a973b6b1ebb70 1061 Pfam PF01568 Molydopterin dinucleotide binding domain 907 1002 1.2E-9 T 11-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TO73_1240 7315915b56c87ba0407a973b6b1ebb70 1061 SMART SM00926 43 114 5.5E-8 T 11-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1240 7315915b56c87ba0407a973b6b1ebb70 1061 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 45 113 1.3E-5 T 11-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1240 7315915b56c87ba0407a973b6b1ebb70 1061 Gene3D G3DSA:3.40.50.740 35 159 1.7E-16 T 11-10-2018 TO73_1240 7315915b56c87ba0407a973b6b1ebb70 1061 SUPERFAMILY SSF53706 44 802 1.08E-92 T 11-10-2018 TO73_1240 7315915b56c87ba0407a973b6b1ebb70 1061 Pfam PF00384 Molybdopterin oxidoreductase 295 717 4.3E-15 T 11-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_0421 76d3551356ec8d45a99a756c62b97deb 945 Gene3D G3DSA:1.25.40.10 310 569 4.4E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0421 76d3551356ec8d45a99a756c62b97deb 945 SUPERFAMILY SSF53335 83 269 2.46E-13 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_0421 76d3551356ec8d45a99a756c62b97deb 945 SUPERFAMILY SSF48452 687 798 1.52E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0421 76d3551356ec8d45a99a756c62b97deb 945 SUPERFAMILY SSF48452 330 413 4.8E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0421 76d3551356ec8d45a99a756c62b97deb 945 SUPERFAMILY SSF81901 477 684 1.26E-6 T 11-10-2018 TO73_0421 76d3551356ec8d45a99a756c62b97deb 945 Gene3D G3DSA:3.40.50.150 103 273 5.4E-9 T 11-10-2018 TO73_0421 76d3551356ec8d45a99a756c62b97deb 945 SMART SM00028 538 571 17.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0421 76d3551356ec8d45a99a756c62b97deb 945 SMART SM00028 734 767 7.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0421 76d3551356ec8d45a99a756c62b97deb 945 SMART SM00028 330 363 2.4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0549 6edda59ef06bc7de759348dcd1f7f4ee 124 SUPERFAMILY SSF56214 2 116 3.4E-17 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TO73_0549 6edda59ef06bc7de759348dcd1f7f4ee 124 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 69 2.3E-12 T 11-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TO73_0549 6edda59ef06bc7de759348dcd1f7f4ee 124 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 119 18.088 T 11-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TO73_0549 6edda59ef06bc7de759348dcd1f7f4ee 124 Gene3D G3DSA:3.90.470.20 1 118 5.4E-25 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TO73_0549 6edda59ef06bc7de759348dcd1f7f4ee 124 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 61 2.0E-12 T 11-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 6 473 4.4E-137 T 11-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 Pfam PF00890 FAD binding domain 7 359 3.1E-84 T 11-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 Pfam PF02910 Fumarate reductase flavoprotein C-term 439 480 1.1E-7 T 11-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 2.9E-10 T 11-10-2018 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.9E-10 T 11-10-2018 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 322 344 2.9E-10 T 11-10-2018 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 SUPERFAMILY SSF56425 213 319 1.09E-35 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 Gene3D G3DSA:3.90.700.10 223 314 6.3E-127 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 Gene3D G3DSA:3.50.50.60 7 370 6.3E-127 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 SUPERFAMILY SSF51905 2 375 3.98E-57 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 SUPERFAMILY SSF46977 397 479 7.59E-18 T 11-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1019 6d9006ba80612e5d444ff95fa039ba64 494 Gene3D G3DSA:1.20.58.100 394 484 2.4E-16 T 11-10-2018 TO73_2325 5ff8f215c6c61d8aba729c072c15b9b9 88 SUPERFAMILY SSF143120 1 41 7.06E-9 T 11-10-2018 IPR036165 YefM-like superfamily TO73_2325 5ff8f215c6c61d8aba729c072c15b9b9 88 Gene3D G3DSA:3.40.1620.10 1 38 4.7E-7 T 11-10-2018 TO73_2325 5ff8f215c6c61d8aba729c072c15b9b9 88 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 53 4.7E-11 T 11-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TO73_2325 5ff8f215c6c61d8aba729c072c15b9b9 88 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 41 3.0E-8 T 11-10-2018 TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 SMART SM01058 318 415 1.8E-36 T 11-10-2018 IPR003711 CarD-like/TRCF domain TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 313 910 1.2E-251 T 11-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 Pfam PF02559 CarD-like/TRCF domain 319 411 9.5E-23 T 11-10-2018 IPR003711 CarD-like/TRCF domain TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 Pfam PF00270 DEAD/DEAH box helicase 444 603 1.3E-16 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 SMART SM00490 665 749 6.4E-15 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 Gene3D G3DSA:3.40.50.300 319 827 1.8E-208 T 11-10-2018 TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 SUPERFAMILY SSF143517 825 970 1.96E-23 T 11-10-2018 IPR037235 TRCF-like, C-terminal domain TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 SUPERFAMILY SSF52540 621 827 8.06E-39 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 Pfam PF03461 TRCF domain 841 925 4.2E-19 T 11-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 SUPERFAMILY SSF52540 21 141 1.08E-6 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 16 923 24.31 T 11-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 Gene3D G3DSA:3.90.1150.50 836 954 3.0E-19 T 11-10-2018 IPR037235 TRCF-like, C-terminal domain TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 SMART SM00487 439 629 2.4E-36 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 Gene3D G3DSA:3.40.50.300 381 620 1.8E-208 T 11-10-2018 TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 SMART SM00982 840 941 6.0E-23 T 11-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 Gene3D G3DSA:2.30.30.840 322 380 1.8E-208 T 11-10-2018 TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 Pfam PF00271 Helicase conserved C-terminal domain 643 747 1.8E-12 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 SUPERFAMILY SSF141259 314 387 2.22E-18 T 11-10-2018 IPR036101 CarD-like/TRCF domain superfamily TO73_1064 3e691c68b3a6bac7c1ee369d7fd8d9e4 978 SUPERFAMILY SSF52540 377 623 1.2E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0995 7b8a75b2c56fae5893b379dab1d2b800 122 Gene3D G3DSA:3.10.129.10 1 117 1.4E-44 T 11-10-2018 TO73_0995 7b8a75b2c56fae5893b379dab1d2b800 122 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 5 110 1.1E-20 T 11-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TO73_0995 7b8a75b2c56fae5893b379dab1d2b800 122 SUPERFAMILY SSF54637 2 115 7.34E-30 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_0995 7b8a75b2c56fae5893b379dab1d2b800 122 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 8 117 6.2E-42 T 11-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 TO73_0995 7b8a75b2c56fae5893b379dab1d2b800 122 Pfam PF03061 Thioesterase superfamily 35 107 1.1E-15 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Pfam PF00623 RNA polymerase Rpb1, domain 2 620 761 1.2E-35 T 11-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:2.40.50.410 148 211 4.1E-34 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:2.40.50.410 398 455 6.3E-38 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Pfam PF04998 RNA polymerase Rpb1, domain 5 1305 1429 3.2E-13 T 11-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Pfam PF05000 RNA polymerase Rpb1, domain 4 984 1050 6.4E-15 T 11-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 SUPERFAMILY SSF64484 3 1485 0.0 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:3.90.105.30 1115 1189 8.4E-48 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Pfam PF04997 RNA polymerase Rpb1, domain 1 2 159 1.4E-33 T 11-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Pfam PF04997 RNA polymerase Rpb1, domain 1 456 618 2.9E-46 T 11-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:1.10.1790.20 1253 1429 2.4E-71 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:2.40.50.100 1269 1330 2.4E-71 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Pfam PF04998 RNA polymerase Rpb1, domain 5 1064 1268 8.6E-42 T 11-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:2.40.50.100 247 308 9.9E-23 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Pfam PF04983 RNA polymerase Rpb1, domain 3 768 953 1.1E-29 T 11-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:1.10.40.90 650 695 1.4E-23 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:1.20.120.1280 1 115 5.6E-5 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:1.10.274.100 769 950 1.1E-61 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 1 1492 17.977 T 11-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:1.10.150.390 1431 1494 4.5E-31 T 11-10-2018 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 Gene3D G3DSA:1.10.132.30 951 1088 3.9E-62 T 11-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0324 3dc7becc5d0f03650a011cdba8a0e967 1524 SMART SM00663 510 793 2.6E-164 T 11-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 190 1.8E-40 T 11-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 SUPERFAMILY SSF47781 66 133 5.0E-18 T 11-10-2018 IPR010994 RuvA domain 2-like TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 SUPERFAMILY SSF50249 1 62 7.42E-12 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 Gene3D G3DSA:1.10.8.10 139 191 4.0E-17 T 11-10-2018 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 SMART SM00278 72 91 0.028 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 SMART SM00278 107 126 84.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 SUPERFAMILY SSF46929 144 190 4.84E-11 T 11-10-2018 IPR036267 RuvA, C-terminal domain superfamily TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 Pfam PF01330 RuvA N terminal domain 1 61 7.7E-16 T 11-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 Gene3D G3DSA:2.40.50.140 1 63 3.3E-23 T 11-10-2018 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 Pfam PF07499 RuvA, C-terminal domain 146 190 9.8E-10 T 11-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 191 27.343 T 11-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 Gene3D G3DSA:1.10.150.20 64 138 1.5E-23 T 11-10-2018 TO73_0152 82c5c780ce82dab2b7bb14907f53487d 191 Pfam PF14520 Helix-hairpin-helix domain 71 128 7.0E-14 T 11-10-2018 TO73_2053 f204b045fce0bf73ebb2126974abe641 359 SUPERFAMILY SSF51569 68 353 1.47E-97 T 11-10-2018 TO73_2053 f204b045fce0bf73ebb2126974abe641 359 Pfam PF00793 DAHP synthetase I family 114 351 4.8E-81 T 11-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TO73_2053 f204b045fce0bf73ebb2126974abe641 359 Gene3D G3DSA:3.20.20.70 93 353 3.6E-99 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_2053 f204b045fce0bf73ebb2126974abe641 359 Pfam PF01817 Chorismate mutase type II 9 86 1.3E-20 T 11-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TO73_2053 f204b045fce0bf73ebb2126974abe641 359 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 94 349 4.1E-122 T 11-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TO73_2053 f204b045fce0bf73ebb2126974abe641 359 SMART SM00830 9 88 2.7E-27 T 11-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TO73_2053 f204b045fce0bf73ebb2126974abe641 359 TIGRFAM TIGR01801 CM_A: chorismate mutase 3 101 1.4E-35 T 11-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TO73_2053 f204b045fce0bf73ebb2126974abe641 359 Gene3D G3DSA:1.20.59.10 1 90 2.4E-30 T 11-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TO73_2053 f204b045fce0bf73ebb2126974abe641 359 SUPERFAMILY SSF48600 4 87 1.83E-20 T 11-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TO73_1315 b687c79afd779dab65a5a698aaea8721 186 Hamap MF_00528 Septum formation protein Maf [maf]. 7 186 29.771 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 TO73_1315 b687c79afd779dab65a5a698aaea8721 186 TIGRFAM TIGR00172 maf: septum formation protein Maf 7 179 8.2E-45 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 TO73_1315 b687c79afd779dab65a5a698aaea8721 186 Gene3D G3DSA:3.90.950.10 5 185 5.3E-58 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TO73_1315 b687c79afd779dab65a5a698aaea8721 186 PIRSF PIRSF006305 3 185 8.9E-48 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 TO73_1315 b687c79afd779dab65a5a698aaea8721 186 SUPERFAMILY SSF52972 7 181 5.49E-52 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TO73_1315 b687c79afd779dab65a5a698aaea8721 186 Pfam PF02545 Maf-like protein 8 179 5.2E-51 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 TO73_0101 b8cc9a21fb13eb0034a39d8d879efb93 531 Pfam PF09210 Domain of unknown function (DUF1957) 433 515 8.6E-22 T 11-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TO73_0101 b8cc9a21fb13eb0034a39d8d879efb93 531 Pfam PF03065 Glycosyl hydrolase family 57 5 367 1.4E-47 T 11-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TO73_0101 b8cc9a21fb13eb0034a39d8d879efb93 531 SUPERFAMILY SSF88688 413 515 3.6E-30 T 11-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TO73_0101 b8cc9a21fb13eb0034a39d8d879efb93 531 SUPERFAMILY SSF88713 2 413 5.78E-123 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TO73_0101 b8cc9a21fb13eb0034a39d8d879efb93 531 Gene3D G3DSA:1.20.1430.10 414 519 4.2E-35 T 11-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TO73_0101 b8cc9a21fb13eb0034a39d8d879efb93 531 Gene3D G3DSA:3.20.110.10 1 413 4.5E-168 T 11-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily TO73_0155 4b922b7eb5de44185981525be0623932 394 SUPERFAMILY SSF47005 93 137 8.89E-11 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TO73_0155 4b922b7eb5de44185981525be0623932 394 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 394 3.5E-150 T 11-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TO73_0155 4b922b7eb5de44185981525be0623932 394 Gene3D G3DSA:2.40.50.100 1 97 2.2E-22 T 11-10-2018 TO73_0155 4b922b7eb5de44185981525be0623932 394 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TO73_0155 4b922b7eb5de44185981525be0623932 394 Pfam PF02817 e3 binding domain 98 133 3.6E-13 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TO73_0155 4b922b7eb5de44185981525be0623932 394 SUPERFAMILY SSF52777 166 393 9.34E-89 T 11-10-2018 TO73_0155 4b922b7eb5de44185981525be0623932 394 SUPERFAMILY SSF51230 2 93 3.26E-23 T 11-10-2018 IPR011053 Single hybrid motif TO73_0155 4b922b7eb5de44185981525be0623932 394 Gene3D G3DSA:3.30.559.10 163 394 4.2E-96 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TO73_0155 4b922b7eb5de44185981525be0623932 394 Gene3D G3DSA:4.10.320.10 98 142 4.1E-13 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TO73_0155 4b922b7eb5de44185981525be0623932 394 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 165 392 2.4E-82 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TO73_0155 4b922b7eb5de44185981525be0623932 394 Pfam PF00364 Biotin-requiring enzyme 3 74 4.9E-18 T 11-10-2018 IPR000089 Biotin/lipoyl attachment TO73_1436 6e771af67daf6934de4fc7de7e4862e2 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 257 3.8E-17 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1436 6e771af67daf6934de4fc7de7e4862e2 259 Gene3D G3DSA:1.10.3720.10 1 259 2.6E-56 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1436 6e771af67daf6934de4fc7de7e4862e2 259 SUPERFAMILY SSF161098 10 249 8.5E-57 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 SUPERFAMILY SSF57783 5 97 2.89E-31 T 11-10-2018 TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 Gene3D G3DSA:3.40.1360.10 229 351 1.3E-25 T 11-10-2018 TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 Gene3D G3DSA:3.90.580.10 3 98 4.4E-36 T 11-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 Gene3D G3DSA:3.90.980.10 101 228 4.5E-40 T 11-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 SUPERFAMILY SSF56731 107 385 1.31E-78 T 11-10-2018 TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 Hamap MF_00974 DNA primase [dnaG]. 1 565 25.292 T 11-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 Pfam PF08275 DNA primase catalytic core, N-terminal domain 117 240 6.3E-37 T 11-10-2018 IPR013264 DNA primase, catalytic core, N-terminal TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 Pfam PF01807 CHC2 zinc finger 5 97 1.3E-31 T 11-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 SMART SM00493 246 318 8.4E-11 T 11-10-2018 IPR006171 TOPRIM domain TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 TIGRFAM TIGR01391 dnaG: DNA primase 5 382 6.1E-114 T 11-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 SMART SM00400 34 88 1.8E-30 T 11-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TO73_1767 b604f366d96d3cc2b2ec6b9a45888343 577 Pfam PF13662 Toprim domain 247 311 8.1E-16 T 11-10-2018 IPR006171 TOPRIM domain TO73_1513 c2086a01012da07df80417e176780ff7 345 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 115 125 - T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 SUPERFAMILY SSF50985 108 343 6.28E-54 T 11-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II TO73_1513 c2086a01012da07df80417e176780ff7 345 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 264 311 1.4E-12 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 178 223 1.2E-7 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 314 344 2.3E-7 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 81 125 8.3E-9 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 128 174 9.8E-10 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 33 77 1.7E-9 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 Gene3D G3DSA:2.130.10.30 15 236 1.5E-53 T 11-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II TO73_1513 c2086a01012da07df80417e176780ff7 345 Gene3D G3DSA:2.130.10.30 237 345 1.2E-32 T 11-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II TO73_1513 c2086a01012da07df80417e176780ff7 345 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 35 51 4.7E-14 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 115 131 4.7E-14 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 310 331 4.7E-14 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 131 145 4.7E-14 T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 67 77 - T 11-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 TO73_1513 c2086a01012da07df80417e176780ff7 345 SUPERFAMILY SSF50985 20 100 5.23E-16 T 11-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II TO73_1135 f7085834597bfffc7346ff47bf47ca64 507 SUPERFAMILY SSF54675 5 153 8.44E-34 T 11-10-2018 TO73_1135 f7085834597bfffc7346ff47bf47ca64 507 SUPERFAMILY SSF51690 148 505 1.45E-101 T 11-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TO73_1135 f7085834597bfffc7346ff47bf47ca64 507 Gene3D G3DSA:3.20.20.70 160 346 7.6E-164 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1135 f7085834597bfffc7346ff47bf47ca64 507 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 192 383 1.5E-4 T 11-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TO73_1135 f7085834597bfffc7346ff47bf47ca64 507 Gene3D G3DSA:3.20.140.10 7 498 7.6E-164 T 11-10-2018 TO73_1135 f7085834597bfffc7346ff47bf47ca64 507 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 7 494 3.1E-131 T 11-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 TO73_1135 f7085834597bfffc7346ff47bf47ca64 507 PIRSF PIRSF000484 1 507 8.5E-146 T 11-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 SUPERFAMILY SSF53784 1 319 5.36E-118 T 11-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 ProSitePatterns PS00433 Phosphofructokinase signature. 246 264 - T 11-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 Gene3D G3DSA:3.40.50.460 141 258 4.1E-109 T 11-10-2018 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.2E-84 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.2E-84 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 242 264 2.2E-84 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 2.2E-84 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 2.2E-84 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 2.2E-84 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 2.2E-84 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 2.2E-84 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 2.2E-84 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 Pfam PF00365 Phosphofructokinase 3 278 4.5E-108 T 11-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 303 2.7E-125 T 11-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 Gene3D G3DSA:3.40.50.450 4 304 4.1E-109 T 11-10-2018 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 321 47.673 T 11-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TO73_2381 268f992aa2bc5a70cc5ae3791331d8f4 322 PIRSF PIRSF000532 1 320 1.7E-120 T 11-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PRINTS PR00477 Phosphoglycerate kinase family signature 309 334 3.1E-83 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PRINTS PR00477 Phosphoglycerate kinase family signature 134 156 3.1E-83 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PRINTS PR00477 Phosphoglycerate kinase family signature 187 206 3.1E-83 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PRINTS PR00477 Phosphoglycerate kinase family signature 343 354 3.1E-83 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 3.1E-83 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PRINTS PR00477 Phosphoglycerate kinase family signature 366 383 3.1E-83 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PRINTS PR00477 Phosphoglycerate kinase family signature 106 121 3.1E-83 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PRINTS PR00477 Phosphoglycerate kinase family signature 164 186 3.1E-83 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 3.1E-83 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 Pfam PF00162 Phosphoglycerate kinase 5 378 3.0E-142 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 390 40.753 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 Gene3D G3DSA:3.40.50.1260 178 390 3.7E-87 T 11-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 PIRSF PIRSF000724 1 390 1.9E-132 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 Gene3D G3DSA:3.40.50.1260 1 177 3.7E-72 T 11-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 11-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1100 8fb7f041d29682d12e2ab86ac961dca5 390 SUPERFAMILY SSF53748 2 389 1.3E-144 T 11-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1677 adb297751536501c11e67e118825df5f 89 Gene3D G3DSA:1.10.443.10 2 83 7.5E-23 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TO73_1677 adb297751536501c11e67e118825df5f 89 SUPERFAMILY SSF56349 3 73 5.59E-19 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TO73_1677 adb297751536501c11e67e118825df5f 89 Pfam PF00589 Phage integrase family 3 68 1.1E-12 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TO73_0242 e662550869f91f7449f36866d058989b 272 PIRSF PIRSF010376 1 268 3.1E-71 T 11-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TO73_0242 e662550869f91f7449f36866d058989b 272 Gene3D G3DSA:3.30.70.890 149 268 4.0E-30 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TO73_0242 e662550869f91f7449f36866d058989b 272 SUPERFAMILY SSF54211 4 146 7.59E-38 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0242 e662550869f91f7449f36866d058989b 272 SUPERFAMILY SSF55060 149 260 8.39E-25 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TO73_0242 e662550869f91f7449f36866d058989b 272 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 5 252 5.3E-48 T 11-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TO73_0242 e662550869f91f7449f36866d058989b 272 Gene3D G3DSA:3.30.230.10 1 147 2.8E-48 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0242 e662550869f91f7449f36866d058989b 272 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 1 265 29.858 T 11-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TO73_0242 e662550869f91f7449f36866d058989b 272 Pfam PF08544 GHMP kinases C terminal 196 258 1.4E-9 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain TO73_0242 e662550869f91f7449f36866d058989b 272 Pfam PF00288 GHMP kinases N terminal domain 78 133 1.5E-8 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 Gene3D G3DSA:2.60.40.650 281 407 1.0E-46 T 11-10-2018 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 Pfam PF00174 Oxidoreductase molybdopterin binding domain 94 256 2.6E-52 T 11-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 Gene3D G3DSA:3.90.420.10 24 280 1.5E-84 T 11-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 TIGRFAM TIGR04555 sulfite_DH_soxC: sulfite dehydrogenase 3 404 1.6E-175 T 11-10-2018 IPR030835 Sulfite dehydrogenase SoxC TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 SUPERFAMILY SSF56524 68 312 5.62E-73 T 11-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 279 392 3.5E-17 T 11-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 82 98 2.0E-22 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 224 237 2.0E-22 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 134 145 2.0E-22 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 240 253 2.0E-22 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 207 223 2.0E-22 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 317 329 2.0E-22 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0521 1d80d15fe8c71b31f14dff731e4cd78d 427 SUPERFAMILY SSF81296 282 396 1.82E-31 T 11-10-2018 IPR014756 Immunoglobulin E-set TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 Pfam PF02772 S-adenosylmethionine synthetase, central domain 123 240 2.4E-45 T 11-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 390 54.958 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 SUPERFAMILY SSF55973 3 107 1.81E-43 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 Gene3D G3DSA:3.30.300.10 108 384 2.6E-172 T 11-10-2018 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 268 276 - T 11-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 SUPERFAMILY SSF55973 119 241 6.67E-49 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 242 378 4.2E-62 T 11-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 3 99 4.8E-40 T 11-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 PIRSF PIRSF000497 1 391 6.1E-163 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 Gene3D G3DSA:3.30.300.10 9 280 2.6E-172 T 11-10-2018 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 SUPERFAMILY SSF55973 242 390 5.89E-65 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 4 388 3.9E-171 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 Gene3D G3DSA:3.30.300.10 4 243 2.6E-172 T 11-10-2018 TO73_2097 2a1fd8318e07d45993b4258c486ec1b2 392 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 124 134 - T 11-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TO73_1292 f7be9b8bdf64b04ec00c02f92a0fe5ef 244 Gene3D G3DSA:3.40.50.300 1 244 3.4E-89 T 11-10-2018 TO73_1292 f7be9b8bdf64b04ec00c02f92a0fe5ef 244 PIRSF PIRSF039085 1 243 2.1E-118 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TO73_1292 f7be9b8bdf64b04ec00c02f92a0fe5ef 244 SMART SM00382 29 215 4.9E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1292 f7be9b8bdf64b04ec00c02f92a0fe5ef 244 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1292 f7be9b8bdf64b04ec00c02f92a0fe5ef 244 Pfam PF00005 ABC transporter 20 167 1.9E-39 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1292 f7be9b8bdf64b04ec00c02f92a0fe5ef 244 SUPERFAMILY SSF52540 4 237 3.93E-85 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0387 8677d632b34a039a8d83ac4d55696d4a 110 Pfam PF00467 KOW motif 9 39 1.8E-6 T 11-10-2018 IPR005824 KOW TO73_0387 8677d632b34a039a8d83ac4d55696d4a 110 SMART SM00739 6 33 7.9E-6 T 11-10-2018 IPR005824 KOW TO73_0387 8677d632b34a039a8d83ac4d55696d4a 110 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 5 101 18.402 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0387 8677d632b34a039a8d83ac4d55696d4a 110 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 42 103 1.5E-24 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0387 8677d632b34a039a8d83ac4d55696d4a 110 Gene3D G3DSA:2.30.30.30 1 104 1.9E-38 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 TO73_0387 8677d632b34a039a8d83ac4d55696d4a 110 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 4 104 2.0E-36 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0387 8677d632b34a039a8d83ac4d55696d4a 110 SUPERFAMILY SSF50104 4 103 8.6E-35 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily TO73_0387 8677d632b34a039a8d83ac4d55696d4a 110 ProSitePatterns PS01108 Ribosomal protein L24 signature. 10 27 - T 11-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0253 0b5ebdda5217b294d4b1769b51d38ee4 854 SUPERFAMILY SSF53706 159 410 9.42E-8 T 11-10-2018 TO73_0253 0b5ebdda5217b294d4b1769b51d38ee4 854 Pfam PF12838 4Fe-4S dicluster domain 618 686 4.4E-7 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_0253 0b5ebdda5217b294d4b1769b51d38ee4 854 Pfam PF12838 4Fe-4S dicluster domain 701 798 5.0E-9 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_0253 0b5ebdda5217b294d4b1769b51d38ee4 854 Gene3D G3DSA:3.30.70.20 697 846 1.1E-25 T 11-10-2018 TO73_0253 0b5ebdda5217b294d4b1769b51d38ee4 854 Gene3D G3DSA:3.30.70.20 608 696 1.5E-16 T 11-10-2018 TO73_0253 0b5ebdda5217b294d4b1769b51d38ee4 854 SUPERFAMILY SSF54862 610 841 2.83E-48 T 11-10-2018 TO73_1458 a2e01ab642e52cb83ec93cd4eb2d7bad 296 Gene3D G3DSA:3.40.50.170 4 196 6.4E-69 T 11-10-2018 TO73_1458 a2e01ab642e52cb83ec93cd4eb2d7bad 296 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 11 193 31.637 T 11-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TO73_1458 a2e01ab642e52cb83ec93cd4eb2d7bad 296 SUPERFAMILY SSF53328 11 199 5.49E-55 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TO73_1458 a2e01ab642e52cb83ec93cd4eb2d7bad 296 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 10 191 3.4E-59 T 11-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TO73_1458 a2e01ab642e52cb83ec93cd4eb2d7bad 296 Pfam PF00551 Formyl transferase 11 187 7.3E-50 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TO73_0259 494c2830f11980769a658d8cfd4b9d5f 358 Gene3D G3DSA:3.30.70.360 160 266 1.0E-128 T 11-10-2018 TO73_0259 494c2830f11980769a658d8cfd4b9d5f 358 SUPERFAMILY SSF53187 8 353 7.43E-44 T 11-10-2018 TO73_0259 494c2830f11980769a658d8cfd4b9d5f 358 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 6 352 31.359 T 11-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 TO73_0259 494c2830f11980769a658d8cfd4b9d5f 358 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 10 352 1.5E-146 T 11-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 TO73_0259 494c2830f11980769a658d8cfd4b9d5f 358 Pfam PF01546 Peptidase family M20/M25/M40 64 349 3.0E-30 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 TO73_0259 494c2830f11980769a658d8cfd4b9d5f 358 Gene3D G3DSA:3.40.630.10 16 341 1.0E-128 T 11-10-2018 TO73_2710 08061c7db30127430222075367f3a953 471 SUPERFAMILY SSF57997 78 229 4.32E-5 T 11-10-2018 TO73_2710 08061c7db30127430222075367f3a953 471 Pfam PF00395 S-layer homology domain 24 65 2.0E-10 T 11-10-2018 IPR001119 S-layer homology domain TO73_2710 08061c7db30127430222075367f3a953 471 Gene3D G3DSA:1.20.5.340 82 233 5.1E-6 T 11-10-2018 TO73_2710 08061c7db30127430222075367f3a953 471 Pfam PF08317 Spc7 kinetochore protein 53 232 1.2E-10 T 11-10-2018 IPR013253 Spc7 kinetochore protein domain TO73_1013 e71d18cbc05ec6b16bccbee66193ce23 225 Gene3D G3DSA:3.40.1010.10 1 123 7.6E-24 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TO73_1013 e71d18cbc05ec6b16bccbee66193ce23 225 SUPERFAMILY SSF53790 2 203 2.36E-30 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TO73_1013 e71d18cbc05ec6b16bccbee66193ce23 225 PIRSF PIRSF036427 1 220 5.0E-38 T 11-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 TO73_1013 e71d18cbc05ec6b16bccbee66193ce23 225 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 198 2.4E-30 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 SUPERFAMILY SSF55957 405 465 7.33E-18 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 SUPERFAMILY SSF53738 7 170 9.42E-44 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 258 2.8E-16 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 SUPERFAMILY SSF53738 157 263 3.14E-20 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 139 7.9E-38 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 SUPERFAMILY SSF53738 249 379 4.32E-29 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 Gene3D G3DSA:3.40.120.10 262 378 8.0E-43 T 11-10-2018 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 265 371 2.6E-24 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 Gene3D G3DSA:3.40.120.10 177 261 6.6E-20 T 11-10-2018 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 102 111 - T 11-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 Gene3D G3DSA:3.30.310.50 379 463 2.5E-24 T 11-10-2018 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 413 461 1.4E-10 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 Gene3D G3DSA:3.40.120.10 2 153 1.0E-50 T 11-10-2018 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 101 115 5.1E-8 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 212 225 5.1E-8 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0783 4f8b09863f74115edf891ce49b75a661 466 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 241 256 5.1E-8 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0956 efbd3275c77220527d5db67e7d1c7d2b 394 SUPERFAMILY SSF53822 30 385 4.12E-64 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_0956 efbd3275c77220527d5db67e7d1c7d2b 394 Gene3D G3DSA:3.40.50.2300 39 355 1.1E-75 T 11-10-2018 TO73_0956 efbd3275c77220527d5db67e7d1c7d2b 394 Gene3D G3DSA:3.40.50.2300 152 289 1.1E-75 T 11-10-2018 TO73_0956 efbd3275c77220527d5db67e7d1c7d2b 394 Pfam PF13458 Periplasmic binding protein 30 382 8.8E-64 T 11-10-2018 IPR028081 Leucine-binding protein domain TO73_0575 6b878422daf3ab319cb1e85e7dcb2c90 236 Pfam PF02754 Cysteine-rich domain 129 210 5.2E-12 T 11-10-2018 IPR004017 Cysteine-rich domain TO73_0575 6b878422daf3ab319cb1e85e7dcb2c90 236 Pfam PF02754 Cysteine-rich domain 3 84 1.4E-15 T 11-10-2018 IPR004017 Cysteine-rich domain TO73_0804 31a146c0a08f3e6d9a235e8821c11ee1 416 Gene3D G3DSA:1.10.150.130 67 186 2.1E-19 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal TO73_0804 31a146c0a08f3e6d9a235e8821c11ee1 416 Pfam PF14657 Arm DNA-binding domain 20 55 4.6E-5 T 11-10-2018 IPR028259 AP2-like integrase, N-terminal domain TO73_0804 31a146c0a08f3e6d9a235e8821c11ee1 416 SUPERFAMILY SSF56349 71 381 9.71E-66 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TO73_0804 31a146c0a08f3e6d9a235e8821c11ee1 416 Gene3D G3DSA:1.10.443.10 188 385 1.5E-50 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TO73_0804 31a146c0a08f3e6d9a235e8821c11ee1 416 Pfam PF00589 Phage integrase family 191 375 1.9E-28 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 Gene3D G3DSA:1.20.120.80 608 791 1.9E-61 T 11-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 246 300 - T 11-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 SUPERFAMILY SSF81442 15 518 7.98E-170 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 17 42 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 164 182 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 314 335 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 92 116 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 377 396 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 135 147 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 193 212 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 244 265 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 64 87 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 427 448 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 290 305 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 349 367 2.3E-85 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 472 1.1E-141 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 Gene3D G3DSA:1.10.287.70 534 607 1.8E-43 T 11-10-2018 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 Pfam PF00510 Cytochrome c oxidase subunit III 550 791 5.4E-25 T 11-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 Gene3D G3DSA:1.20.210.10 1 533 6.8E-212 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 19 519 8.3E-210 T 11-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TO73_2236 bd3c7b47200e2db49c43925e263a58e9 791 SUPERFAMILY SSF81452 547 791 7.01E-58 T 11-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0630 348ecc15fcfc2b9940a9c284b269f251 436 Pfam PF01546 Peptidase family M20/M25/M40 67 427 6.4E-36 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 TO73_0630 348ecc15fcfc2b9940a9c284b269f251 436 Gene3D G3DSA:3.40.630.10 5 423 3.3E-164 T 11-10-2018 TO73_0630 348ecc15fcfc2b9940a9c284b269f251 436 SUPERFAMILY SSF53187 6 431 4.29E-61 T 11-10-2018 TO73_0630 348ecc15fcfc2b9940a9c284b269f251 436 Gene3D G3DSA:3.30.70.360 176 345 3.3E-164 T 11-10-2018 TO73_0630 348ecc15fcfc2b9940a9c284b269f251 436 Pfam PF07687 Peptidase dimerisation domain 173 331 2.4E-21 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 292 395 7.8E-12 T 11-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 Gene3D G3DSA:2.60.40.650 291 407 3.7E-31 T 11-10-2018 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 Pfam PF00174 Oxidoreductase molybdopterin binding domain 92 250 2.0E-43 T 11-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 289 301 7.7E-14 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 67 83 7.7E-14 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 125 136 7.7E-14 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 199 215 7.7E-14 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 216 229 7.7E-14 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 232 245 7.7E-14 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 PRINTS PR00407 Eukaryotic molybdopterin domain signature 328 340 7.7E-14 T 11-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 SUPERFAMILY SSF81296 293 406 7.7E-29 T 11-10-2018 IPR014756 Immunoglobulin E-set TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 Gene3D G3DSA:3.90.420.10 25 269 2.7E-58 T 11-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TO73_0608 27bb379d458432bc88b9b19ff49a6b9c 407 SUPERFAMILY SSF56524 35 261 8.76E-54 T 11-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TO73_0507 5102729a9b2c4242c9c2491be923113e 341 SUPERFAMILY SSF52540 131 335 1.45E-20 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0507 5102729a9b2c4242c9c2491be923113e 341 Pfam PF05673 Protein of unknown function (DUF815) 112 335 2.3E-60 T 11-10-2018 IPR008533 Domain of unknown function DUF815 TO73_0507 5102729a9b2c4242c9c2491be923113e 341 Gene3D G3DSA:3.40.50.300 125 261 2.5E-10 T 11-10-2018 TO73_2335 a52ff75f9128f879187a17e968341c16 231 SUPERFAMILY SSF51261 97 203 1.62E-15 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_2335 a52ff75f9128f879187a17e968341c16 231 Gene3D G3DSA:2.70.70.10 73 210 7.7E-16 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_2335 a52ff75f9128f879187a17e968341c16 231 Pfam PF01551 Peptidase family M23 96 202 6.3E-11 T 11-10-2018 IPR016047 Peptidase M23 TO73_0760 400b589e3ba1e50efbba21b29196c429 563 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 62 136 3.3E-13 T 11-10-2018 IPR010094 Transposase (putative), N-terminal TO73_0760 400b589e3ba1e50efbba21b29196c429 563 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 314 392 2.7E-13 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_1457 83829a0a471130be84316943ea3e2118 417 Gene3D G3DSA:3.30.1490.20 118 183 2.0E-21 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TO73_1457 83829a0a471130be84316943ea3e2118 417 SUPERFAMILY SSF51246 320 412 2.15E-29 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TO73_1457 83829a0a471130be84316943ea3e2118 417 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 11-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_1457 83829a0a471130be84316943ea3e2118 417 SMART SM01209 100 287 7.1E-109 T 11-10-2018 TO73_1457 83829a0a471130be84316943ea3e2118 417 SUPERFAMILY SSF52440 1 100 1.11E-32 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TO73_1457 83829a0a471130be84316943ea3e2118 417 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 99 1.5E-34 T 11-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_1457 83829a0a471130be84316943ea3e2118 417 SMART SM01210 321 412 9.3E-49 T 11-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_1457 83829a0a471130be84316943ea3e2118 417 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 412 5.5E-153 T 11-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_1457 83829a0a471130be84316943ea3e2118 417 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 322 409 2.0E-26 T 11-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_1457 83829a0a471130be84316943ea3e2118 417 Gene3D G3DSA:3.30.470.20 184 320 1.3E-55 T 11-10-2018 TO73_1457 83829a0a471130be84316943ea3e2118 417 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 100 287 5.3E-68 T 11-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_1457 83829a0a471130be84316943ea3e2118 417 Gene3D G3DSA:3.90.600.10 321 413 3.2E-35 T 11-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_1457 83829a0a471130be84316943ea3e2118 417 SUPERFAMILY SSF56059 101 315 6.89E-57 T 11-10-2018 TO73_1457 83829a0a471130be84316943ea3e2118 417 Gene3D G3DSA:3.40.50.20 1 92 4.7E-36 T 11-10-2018 TO73_1457 83829a0a471130be84316943ea3e2118 417 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 412 41.778 T 11-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_1161 fdaf97369c2c95032a9fc58e3cde93b9 302 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 4 297 28.324 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TO73_1161 fdaf97369c2c95032a9fc58e3cde93b9 302 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 281 4.5E-74 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TO73_1161 fdaf97369c2c95032a9fc58e3cde93b9 302 SUPERFAMILY SSF52540 6 147 2.17E-15 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1161 fdaf97369c2c95032a9fc58e3cde93b9 302 Pfam PF01715 IPP transferase 37 276 1.5E-68 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TO73_1161 fdaf97369c2c95032a9fc58e3cde93b9 302 Gene3D G3DSA:1.10.20.140 111 178 3.4E-84 T 11-10-2018 TO73_1161 fdaf97369c2c95032a9fc58e3cde93b9 302 Gene3D G3DSA:3.40.50.300 8 275 3.4E-84 T 11-10-2018 TO73_1339 69442ea75836b72f64af69ca66f4b3e1 173 SUPERFAMILY SSF55729 2 168 9.61E-34 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_1339 69442ea75836b72f64af69ca66f4b3e1 173 Gene3D G3DSA:3.40.630.30 2 173 1.1E-54 T 11-10-2018 TO73_1339 69442ea75836b72f64af69ca66f4b3e1 173 Pfam PF00583 Acetyltransferase (GNAT) family 57 143 2.7E-14 T 11-10-2018 IPR000182 GNAT domain TO73_0184 46e8b8e847cee593c35ef0da99cec0e0 426 Gene3D G3DSA:3.40.50.300 3 172 2.6E-25 T 11-10-2018 TO73_0184 46e8b8e847cee593c35ef0da99cec0e0 426 Gene3D G3DSA:3.30.420.240 222 403 1.1E-44 T 11-10-2018 TO73_0184 46e8b8e847cee593c35ef0da99cec0e0 426 Pfam PF17289 Terminase RNaseH-like domain 247 401 2.0E-12 T 11-10-2018 IPR035421 Terminase, large subunit gp17-like TO73_0184 46e8b8e847cee593c35ef0da99cec0e0 426 Pfam PF03237 Terminase-like family 32 226 1.3E-10 T 11-10-2018 IPR004921 Terminase large subunit, T4likevirus-type TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 SUPERFAMILY SSF63418 1 97 4.84E-21 T 11-10-2018 IPR035911 MurE/MurF, N-terminal TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 Gene3D G3DSA:3.40.1390.10 2 98 2.6E-22 T 11-10-2018 TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 401 1.5E-18 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 Gene3D G3DSA:3.40.1190.10 99 321 5.8E-61 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 470 28.442 T 11-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 SUPERFAMILY SSF53623 99 317 2.75E-50 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 Gene3D G3DSA:3.90.190.20 322 475 7.3E-47 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 Pfam PF01225 Mur ligase family, catalytic domain 19 96 1.3E-4 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 SUPERFAMILY SSF53244 318 471 4.27E-36 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 Pfam PF08245 Mur ligase middle domain 108 298 3.4E-37 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TO73_1518 4fdb8ab0f51fda502e805cf991d40bb1 486 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 18 470 7.9E-126 T 11-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TO73_1966 8b4261e78f2870dcd3978362f0ca9fe4 220 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 3.0E-67 T 11-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TO73_1966 8b4261e78f2870dcd3978362f0ca9fe4 220 SUPERFAMILY SSF109755 2 214 4.5E-68 T 11-10-2018 TO73_1966 8b4261e78f2870dcd3978362f0ca9fe4 220 PIRSF PIRSF003107 1 217 4.5E-67 T 11-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TO73_1966 8b4261e78f2870dcd3978362f0ca9fe4 220 Pfam PF01895 PhoU domain 119 204 5.1E-22 T 11-10-2018 IPR026022 PhoU domain TO73_1966 8b4261e78f2870dcd3978362f0ca9fe4 220 Pfam PF01895 PhoU domain 18 103 3.1E-21 T 11-10-2018 IPR026022 PhoU domain TO73_1966 8b4261e78f2870dcd3978362f0ca9fe4 220 Gene3D G3DSA:1.20.58.220 112 219 2.2E-37 T 11-10-2018 IPR038078 PhoU-like domain superfamily TO73_1966 8b4261e78f2870dcd3978362f0ca9fe4 220 Gene3D G3DSA:1.20.58.220 1 111 2.4E-34 T 11-10-2018 IPR038078 PhoU-like domain superfamily TO73_0520 af5cfdd342778980c1aa070ec7b2542d 427 Gene3D G3DSA:3.50.50.60 156 286 8.6E-87 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0520 af5cfdd342778980c1aa070ec7b2542d 427 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 366 424 1.8E-10 T 11-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 TO73_0520 af5cfdd342778980c1aa070ec7b2542d 427 SUPERFAMILY SSF55424 364 425 1.43E-9 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TO73_0520 af5cfdd342778980c1aa070ec7b2542d 427 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 2 22 3.9E-6 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TO73_0520 af5cfdd342778980c1aa070ec7b2542d 427 Gene3D G3DSA:3.50.50.60 44 346 8.6E-87 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0520 af5cfdd342778980c1aa070ec7b2542d 427 SUPERFAMILY SSF51905 170 286 1.3E-28 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0520 af5cfdd342778980c1aa070ec7b2542d 427 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 23 9.1E-4 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TO73_0520 af5cfdd342778980c1aa070ec7b2542d 427 SUPERFAMILY SSF51905 43 161 3.84E-24 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0520 af5cfdd342778980c1aa070ec7b2542d 427 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 44 155 1.2E-10 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TO73_0505 67281a2facd27acf3a25e8ab76429b57 141 PIRSF PIRSF002181 1 141 2.5E-53 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TO73_0505 67281a2facd27acf3a25e8ab76429b57 141 Pfam PF00572 Ribosomal protein L13 12 135 3.4E-56 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TO73_0505 67281a2facd27acf3a25e8ab76429b57 141 Gene3D G3DSA:3.90.1180.10 1 140 1.6E-64 T 11-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0505 67281a2facd27acf3a25e8ab76429b57 141 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 13 139 28.853 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TO73_0505 67281a2facd27acf3a25e8ab76429b57 141 SUPERFAMILY SSF52161 6 140 3.66E-56 T 11-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0505 67281a2facd27acf3a25e8ab76429b57 141 ProSitePatterns PS00783 Ribosomal protein L13 signature. 103 125 - T 11-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TO73_0505 67281a2facd27acf3a25e8ab76429b57 141 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 139 2.9E-60 T 11-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_2866 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_2866 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_0637 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_0637 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_1590 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_1590 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_0926 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_0926 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_0668 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_0668 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_0018 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_0018 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_0340 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_0340 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_2194 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_2194 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_2837 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_2837 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_1418 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 11-10-2018 IPR025457 Domain of unknown function DUF4277 TO73_1418 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_0091 56cca6aea110cf2e20846b423ed28850 376 Gene3D G3DSA:3.20.20.70 1 271 1.7E-108 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0091 56cca6aea110cf2e20846b423ed28850 376 Gene3D G3DSA:1.10.238.260 272 376 6.4E-34 T 11-10-2018 TO73_0091 56cca6aea110cf2e20846b423ed28850 376 Pfam PF00682 HMGL-like 5 265 1.7E-67 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TO73_0091 56cca6aea110cf2e20846b423ed28850 376 SUPERFAMILY SSF51569 2 282 3.11E-65 T 11-10-2018 TO73_0091 56cca6aea110cf2e20846b423ed28850 376 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 192 205 - T 11-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_0091 56cca6aea110cf2e20846b423ed28850 376 TIGRFAM TIGR02146 LysS_fung_arch: homocitrate synthase 6 354 4.0E-161 T 11-10-2018 IPR011872 Homocitrate synthase, fungi/archaea GO:0004410|GO:0019752|GO:0019878|GO:0046912 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 TO73_0091 56cca6aea110cf2e20846b423ed28850 376 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 11-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 SUPERFAMILY SSF55681 144 481 3.38E-114 T 11-10-2018 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 7 483 42.205 T 11-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 Pfam PF01336 OB-fold nucleic acid binding domain 53 128 2.0E-16 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 Gene3D G3DSA:2.40.50.140 1 137 4.3E-37 T 11-10-2018 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 Gene3D G3DSA:3.30.930.10 140 492 2.5E-131 T 11-10-2018 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 2 484 4.8E-178 T 11-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 Pfam PF00152 tRNA synthetases class II (D, K and N) 144 480 5.1E-83 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 181 191 1.5E-37 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 365 381 1.5E-37 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 197 213 1.5E-37 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 261 1.5E-37 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 226 239 1.5E-37 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_0702 dfe74b7784799e84489e487f2574bb2a 492 SUPERFAMILY SSF50249 1 137 2.1E-34 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_2258 6b36429621b5da540b22204528d64c84 530 Gene3D G3DSA:2.40.50.140 193 279 3.7E-29 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 PRINTS PR00681 Ribosomal protein S1 signature 101 120 2.7E-57 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 PRINTS PR00681 Ribosomal protein S1 signature 125 141 2.7E-57 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 PRINTS PR00681 Ribosomal protein S1 signature 172 192 2.7E-57 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 PRINTS PR00681 Ribosomal protein S1 signature 51 65 2.7E-57 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 PRINTS PR00681 Ribosomal protein S1 signature 143 160 2.7E-57 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 PRINTS PR00681 Ribosomal protein S1 signature 347 365 2.7E-57 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 PRINTS PR00681 Ribosomal protein S1 signature 307 326 2.7E-57 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 PRINTS PR00681 Ribosomal protein S1 signature 33 51 2.7E-57 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 PRINTS PR00681 Ribosomal protein S1 signature 229 250 2.7E-57 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 SUPERFAMILY SSF50249 364 454 7.38E-27 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_2258 6b36429621b5da540b22204528d64c84 530 SUPERFAMILY SSF50249 119 202 2.5E-16 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_2258 6b36429621b5da540b22204528d64c84 530 Gene3D G3DSA:2.40.50.140 377 459 6.3E-28 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 SUPERFAMILY SSF50249 206 294 6.29E-28 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_2258 6b36429621b5da540b22204528d64c84 530 SMART SM00316 120 188 8.1E-12 T 11-10-2018 IPR022967 RNA-binding domain, S1 TO73_2258 6b36429621b5da540b22204528d64c84 530 SMART SM00316 379 450 1.8E-26 T 11-10-2018 IPR022967 RNA-binding domain, S1 TO73_2258 6b36429621b5da540b22204528d64c84 530 SMART SM00316 31 104 2.8E-18 T 11-10-2018 IPR022967 RNA-binding domain, S1 TO73_2258 6b36429621b5da540b22204528d64c84 530 SMART SM00316 292 364 8.1E-27 T 11-10-2018 IPR022967 RNA-binding domain, S1 TO73_2258 6b36429621b5da540b22204528d64c84 530 SMART SM00316 207 277 3.6E-28 T 11-10-2018 IPR022967 RNA-binding domain, S1 TO73_2258 6b36429621b5da540b22204528d64c84 530 Gene3D G3DSA:2.40.50.140 19 114 5.4E-22 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 Pfam PF00575 S1 RNA binding domain 291 364 2.9E-19 T 11-10-2018 IPR003029 S1 domain GO:0003676 TO73_2258 6b36429621b5da540b22204528d64c84 530 Pfam PF00575 S1 RNA binding domain 31 104 3.9E-12 T 11-10-2018 IPR003029 S1 domain GO:0003676 TO73_2258 6b36429621b5da540b22204528d64c84 530 Pfam PF00575 S1 RNA binding domain 379 450 1.6E-20 T 11-10-2018 IPR003029 S1 domain GO:0003676 TO73_2258 6b36429621b5da540b22204528d64c84 530 Pfam PF00575 S1 RNA binding domain 207 277 1.9E-21 T 11-10-2018 IPR003029 S1 domain GO:0003676 TO73_2258 6b36429621b5da540b22204528d64c84 530 Pfam PF00575 S1 RNA binding domain 120 188 4.7E-10 T 11-10-2018 IPR003029 S1 domain GO:0003676 TO73_2258 6b36429621b5da540b22204528d64c84 530 Gene3D G3DSA:2.40.50.140 284 376 8.8E-31 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 Gene3D G3DSA:2.40.50.140 115 192 1.4E-11 T 11-10-2018 TO73_2258 6b36429621b5da540b22204528d64c84 530 SUPERFAMILY SSF50249 13 129 8.21E-23 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_2258 6b36429621b5da540b22204528d64c84 530 SUPERFAMILY SSF50249 281 377 7.46E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1147 dbc1fd05b1fd6d4f1321fd7fe5318307 257 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 5 42 3.5E-8 T 11-10-2018 TO73_1147 dbc1fd05b1fd6d4f1321fd7fe5318307 257 PIRSF PIRSF017269 4 256 4.3E-58 T 11-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TO73_1147 dbc1fd05b1fd6d4f1321fd7fe5318307 257 SUPERFAMILY SSF53335 5 253 4.14E-62 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1147 dbc1fd05b1fd6d4f1321fd7fe5318307 257 Gene3D G3DSA:3.40.50.150 7 257 1.6E-80 T 11-10-2018 TO73_1147 dbc1fd05b1fd6d4f1321fd7fe5318307 257 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 62 232 1.7E-18 T 11-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TO73_0780 80fda75561af7979d220214fb9468ff1 317 Gene3D G3DSA:3.90.25.10 169 304 7.4E-115 T 11-10-2018 TO73_0780 80fda75561af7979d220214fb9468ff1 317 SUPERFAMILY SSF51735 3 308 2.09E-84 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0780 80fda75561af7979d220214fb9468ff1 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 238 1.5E-82 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TO73_0780 80fda75561af7979d220214fb9468ff1 317 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 4 306 52.343 T 11-10-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00051+1.1.1.271|KEGG: 00520+1.1.1.271|MetaCyc: PWY-66|Reactome: R-HSA-6787639 TO73_0780 80fda75561af7979d220214fb9468ff1 317 Gene3D G3DSA:3.40.50.720 7 295 7.4E-115 T 11-10-2018 TO73_0673 20b903c8139d9332f0d1dbfe7c5cc04a 392 Gene3D G3DSA:1.10.287.470 91 216 7.3E-33 T 11-10-2018 TO73_0673 20b903c8139d9332f0d1dbfe7c5cc04a 392 Gene3D G3DSA:2.40.420.20 46 375 7.3E-33 T 11-10-2018 TO73_0673 20b903c8139d9332f0d1dbfe7c5cc04a 392 Gene3D G3DSA:2.40.30.170 47 319 7.3E-33 T 11-10-2018 TO73_0673 20b903c8139d9332f0d1dbfe7c5cc04a 392 Gene3D G3DSA:2.40.50.100 58 251 7.3E-33 T 11-10-2018 TO73_0673 20b903c8139d9332f0d1dbfe7c5cc04a 392 SUPERFAMILY SSF111369 141 271 1.44E-11 T 11-10-2018 TO73_0673 20b903c8139d9332f0d1dbfe7c5cc04a 392 SUPERFAMILY SSF111369 56 142 1.44E-7 T 11-10-2018 TO73_0673 20b903c8139d9332f0d1dbfe7c5cc04a 392 Pfam PF13437 HlyD family secretion protein 216 306 4.9E-10 T 11-10-2018 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 139 152 6.2E-51 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 519 539 6.2E-51 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 180 196 6.2E-51 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 366 386 6.2E-51 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 561 590 6.2E-51 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 238 253 6.2E-51 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 693 719 6.2E-51 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 521 533 - T 11-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 Pfam PF00311 Phosphoenolpyruvate carboxylase 135 857 4.6E-197 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 857 16.722 T 11-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 140 151 - T 11-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TO73_1126 a0f94e6952febd4eb8c0d1636e37eff7 857 SUPERFAMILY SSF51621 11 857 1.04E-238 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 Gene3D G3DSA:1.10.1750.10 344 441 3.4E-32 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 Pfam PF00308 Bacterial dnaA protein 107 324 1.0E-98 T 11-10-2018 IPR013317 Chromosomal replication initiator protein DnaA TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 SUPERFAMILY SSF52540 106 319 3.32E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 Gene3D G3DSA:3.30.300.180 3 79 3.9E-16 T 11-10-2018 IPR038454 DnaA, N-terminal domain superfamily TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 SUPERFAMILY SSF48295 339 440 4.97E-33 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 9 439 2.9E-170 T 11-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 352 419 2.3E-28 T 11-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 SMART SM00760 350 419 1.8E-38 T 11-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 ProSitePatterns PS01008 DnaA protein signature. 400 419 - T 11-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 SMART SM00382 139 267 4.1E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 Gene3D G3DSA:3.40.50.300 91 271 4.6E-54 T 11-10-2018 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 Pfam PF11638 DnaA N-terminal domain 7 67 2.2E-18 T 11-10-2018 IPR024633 DnaA N-terminal domain TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 6 441 33.536 T 11-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 Gene3D G3DSA:1.10.8.60 273 343 2.9E-25 T 11-10-2018 TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 172 186 1.5E-51 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 238 265 1.5E-51 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 140 160 1.5E-51 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 204 218 1.5E-51 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TO73_0001 2e5cc3d250ad17353227b7d16b334c26 441 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 400 419 1.5E-51 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TO73_1481 52c613a2fe940f601d7b465c06d1502b 357 SUPERFAMILY SSF102588 78 332 8.11E-45 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TO73_1481 52c613a2fe940f601d7b465c06d1502b 357 Pfam PF02585 GlcNAc-PI de-N-acetylase 81 245 2.6E-26 T 11-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TO73_1481 52c613a2fe940f601d7b465c06d1502b 357 Gene3D G3DSA:3.40.50.10320 74 330 5.0E-48 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TO73_1897 94849cf43c45867b6a11726be4428b61 513 Gene3D G3DSA:3.40.50.300 212 364 1.9E-47 T 11-10-2018 TO73_1897 94849cf43c45867b6a11726be4428b61 513 SMART SM00487 20 214 1.1E-64 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_1897 94849cf43c45867b6a11726be4428b61 513 Pfam PF00271 Helicase conserved C-terminal domain 225 332 5.5E-29 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_1897 94849cf43c45867b6a11726be4428b61 513 Gene3D G3DSA:3.40.50.300 1 207 1.5E-85 T 11-10-2018 TO73_1897 94849cf43c45867b6a11726be4428b61 513 Pfam PF00270 DEAD/DEAH box helicase 25 187 5.4E-47 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TO73_1897 94849cf43c45867b6a11726be4428b61 513 SUPERFAMILY SSF52540 72 351 2.55E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1897 94849cf43c45867b6a11726be4428b61 513 Gene3D G3DSA:3.30.70.1800 366 493 1.2E-53 T 11-10-2018 TO73_1897 94849cf43c45867b6a11726be4428b61 513 SMART SM00490 251 332 2.0E-33 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_1897 94849cf43c45867b6a11726be4428b61 513 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 11-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TO73_1984 506d0c3b2602a07242c18d449d6d7172 235 Pfam PF00106 short chain dehydrogenase 12 134 4.1E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1984 506d0c3b2602a07242c18d449d6d7172 235 Gene3D G3DSA:3.40.50.720 1 218 1.9E-26 T 11-10-2018 TO73_1984 506d0c3b2602a07242c18d449d6d7172 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.2E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1984 506d0c3b2602a07242c18d449d6d7172 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.2E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1984 506d0c3b2602a07242c18d449d6d7172 235 SUPERFAMILY SSF51735 6 183 4.13E-28 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1791 bcdc3c15c7dd345c792ce6510c7ec97a 260 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 255 1.6E-105 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TO73_1791 bcdc3c15c7dd345c792ce6510c7ec97a 260 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 260 43.096 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TO73_1791 bcdc3c15c7dd345c792ce6510c7ec97a 260 PIRSF PIRSF000388 1 260 2.1E-105 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TO73_1791 bcdc3c15c7dd345c792ce6510c7ec97a 260 SUPERFAMILY SSF51621 3 260 3.57E-101 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TO73_1791 bcdc3c15c7dd345c792ce6510c7ec97a 260 Gene3D G3DSA:3.20.20.60 1 260 7.8E-111 T 11-10-2018 TO73_1791 bcdc3c15c7dd345c792ce6510c7ec97a 260 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 260 1.8E-102 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TO73_1914 ef773ccf1d778d6b6a0bed6ec324743b 584 Pfam PF12469 CRISPR-associated protein 4 100 2.3E-18 T 11-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal TO73_1914 ef773ccf1d778d6b6a0bed6ec324743b 584 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 4 448 2.2E-91 T 11-10-2018 IPR013407 CRISPR-associated protein Cmr2 TO73_1914 ef773ccf1d778d6b6a0bed6ec324743b 584 Gene3D G3DSA:3.30.70.2220 2 151 2.8E-18 T 11-10-2018 IPR038242 Cmr2, N-terminal domain superfamily TO73_1914 ef773ccf1d778d6b6a0bed6ec324743b 584 Gene3D G3DSA:3.30.70.2230 323 471 1.6E-38 T 11-10-2018 TO73_1203 3af16d662fbbf77cc1382d7b16166061 256 SUPERFAMILY SSF52540 52 227 2.81E-16 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1203 3af16d662fbbf77cc1382d7b16166061 256 Pfam PF13401 AAA domain 53 159 2.6E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1203 3af16d662fbbf77cc1382d7b16166061 256 Gene3D G3DSA:3.40.50.300 35 178 1.0E-8 T 11-10-2018 TO73_1203 3af16d662fbbf77cc1382d7b16166061 256 SMART SM00382 50 184 0.0042 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2030 e26bca2d7225d652db0ffc12f98166a1 516 SUPERFAMILY SSF53720 4 515 1.22E-157 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TO73_2030 e26bca2d7225d652db0ffc12f98166a1 516 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 6 516 7.1E-220 T 11-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 TO73_2030 e26bca2d7225d652db0ffc12f98166a1 516 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 315 326 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TO73_2030 e26bca2d7225d652db0ffc12f98166a1 516 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 287 294 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TO73_2030 e26bca2d7225d652db0ffc12f98166a1 516 Gene3D G3DSA:3.40.605.10 40 503 9.8E-186 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TO73_2030 e26bca2d7225d652db0ffc12f98166a1 516 Gene3D G3DSA:3.40.309.10 290 479 9.8E-186 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TO73_2030 e26bca2d7225d652db0ffc12f98166a1 516 Pfam PF00171 Aldehyde dehydrogenase family 46 512 9.8E-155 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TO73_2201 088c12333a932466baaa2665b472c5b0 905 Gene3D G3DSA:3.40.50.920 727 904 2.4E-59 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_2201 088c12333a932466baaa2665b472c5b0 905 SUPERFAMILY SSF52922 723 902 5.0E-46 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_2201 088c12333a932466baaa2665b472c5b0 905 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 377 445 2.7E-4 T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TO73_2201 088c12333a932466baaa2665b472c5b0 905 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 92 313 6.5E-9 T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TO73_2201 088c12333a932466baaa2665b472c5b0 905 Gene3D G3DSA:3.40.50.970 489 722 6.1E-102 T 11-10-2018 TO73_2201 088c12333a932466baaa2665b472c5b0 905 SUPERFAMILY SSF52518 491 717 4.81E-89 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_2201 088c12333a932466baaa2665b472c5b0 905 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 21 902 0.0 T 11-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TO73_2201 088c12333a932466baaa2665b472c5b0 905 SUPERFAMILY SSF52518 69 483 1.82E-127 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_2201 088c12333a932466baaa2665b472c5b0 905 Gene3D G3DSA:3.40.50.970 68 488 3.4E-126 T 11-10-2018 TO73_2201 088c12333a932466baaa2665b472c5b0 905 PIRSF PIRSF000156 9 905 0.0 T 11-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TO73_2201 088c12333a932466baaa2665b472c5b0 905 SMART SM00861 511 716 0.0099 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_1421 50c9ae19b4fbc1ece2fbafb65f530895 185 SUPERFAMILY SSF52980 11 179 7.51E-27 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1421 50c9ae19b4fbc1ece2fbafb65f530895 185 Pfam PF05685 Putative restriction endonuclease 14 176 2.7E-31 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1421 50c9ae19b4fbc1ece2fbafb65f530895 185 Gene3D G3DSA:3.90.1570.10 4 182 5.4E-18 T 11-10-2018 TO73_1295 d12001a75c694d562665d8a4e18797ad 263 SUPERFAMILY SSF161098 52 244 6.41E-46 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1295 d12001a75c694d562665d8a4e18797ad 263 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 50 153 1.4E-23 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TO73_1295 d12001a75c694d562665d8a4e18797ad 263 Gene3D G3DSA:1.10.3720.10 42 260 3.3E-53 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1295 d12001a75c694d562665d8a4e18797ad 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 259 2.9E-21 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1708 08001ec722cb53c5bb67ef5aa317dd88 387 Gene3D G3DSA:3.20.20.210 43 387 2.9E-141 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TO73_1708 08001ec722cb53c5bb67ef5aa317dd88 387 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 184 200 - T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TO73_1708 08001ec722cb53c5bb67ef5aa317dd88 387 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 67 76 - T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TO73_1708 08001ec722cb53c5bb67ef5aa317dd88 387 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 54 384 1.7E-126 T 11-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TO73_1708 08001ec722cb53c5bb67ef5aa317dd88 387 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 51 384 4.7E-128 T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TO73_1708 08001ec722cb53c5bb67ef5aa317dd88 387 SUPERFAMILY SSF51726 50 385 3.14E-108 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TO73_1708 08001ec722cb53c5bb67ef5aa317dd88 387 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 51 386 46.481 T 11-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TO73_2743 3c16f2aeba684f979d3c6ba9a7042c4b 292 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 33 136 1.6E-29 T 11-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TO73_2743 3c16f2aeba684f979d3c6ba9a7042c4b 292 SUPERFAMILY SSF110849 23 143 1.38E-27 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TO73_2743 3c16f2aeba684f979d3c6ba9a7042c4b 292 Pfam PF02195 ParB-like nuclease domain 24 107 8.2E-22 T 11-10-2018 IPR003115 ParB/Sulfiredoxin TO73_2743 3c16f2aeba684f979d3c6ba9a7042c4b 292 SMART SM00470 21 108 2.8E-30 T 11-10-2018 IPR003115 ParB/Sulfiredoxin TO73_2743 3c16f2aeba684f979d3c6ba9a7042c4b 292 SUPERFAMILY SSF109709 102 241 2.09E-17 T 11-10-2018 TO73_2743 3c16f2aeba684f979d3c6ba9a7042c4b 292 Gene3D G3DSA:3.90.1530.30 33 94 1.3E-23 T 11-10-2018 TO73_2743 3c16f2aeba684f979d3c6ba9a7042c4b 292 Gene3D G3DSA:1.10.10.2830 149 242 1.1E-6 T 11-10-2018 TO73_2743 3c16f2aeba684f979d3c6ba9a7042c4b 292 Gene3D G3DSA:1.10.10.2830 95 147 9.8E-10 T 11-10-2018 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 13 793 22.122 T 11-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 14 798 0.0 T 11-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 PIRSF PIRSF037677 214 772 1.1E-108 T 11-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 PIRSF PIRSF037677 12 190 1.5E-24 T 11-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Pfam PF05190 MutS family domain IV 403 492 1.3E-27 T 11-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 SUPERFAMILY SSF53150 126 265 1.83E-29 T 11-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 657 673 - T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Pfam PF05192 MutS domain III 255 534 5.8E-39 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Gene3D G3DSA:3.40.50.300 542 765 7.4E-98 T 11-10-2018 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Gene3D G3DSA:3.40.1170.10 2 126 3.7E-46 T 11-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Pfam PF01624 MutS domain I 15 124 2.6E-35 T 11-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Pfam PF00488 MutS domain V 580 762 6.3E-78 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 SUPERFAMILY SSF52540 542 760 1.57E-52 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 SUPERFAMILY SSF48334 269 540 1.83E-79 T 11-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Gene3D G3DSA:1.10.1420.10 375 510 2.4E-102 T 11-10-2018 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Gene3D G3DSA:1.10.1420.10 258 537 2.4E-102 T 11-10-2018 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Pfam PF05188 MutS domain II 132 189 7.1E-9 T 11-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 Gene3D G3DSA:3.30.420.110 131 248 2.7E-50 T 11-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 SMART SM00534 576 760 1.0E-111 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 SUPERFAMILY SSF55271 11 120 1.07E-35 T 11-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 TO73_0609 3d316902e9f1ec6658fb5e7c4cca52c9 811 SMART SM00533 267 564 1.3E-102 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TO73_2343 63946c9b9f0f60c894017a06773a6eac 158 PIRSF PIRSF029256 1 151 7.4E-54 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 TO73_2343 63946c9b9f0f60c894017a06773a6eac 158 SUPERFAMILY SSF75217 2 148 1.77E-41 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases TO73_2343 63946c9b9f0f60c894017a06773a6eac 158 Gene3D G3DSA:3.40.1280.10 1 148 9.8E-60 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TO73_2343 63946c9b9f0f60c894017a06773a6eac 158 Pfam PF00588 SpoU rRNA Methylase family 2 140 3.2E-34 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TO73_2343 63946c9b9f0f60c894017a06773a6eac 158 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 149 32.459 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 TO73_0303 30452c8dce4d5a0365ad755f18d61351 128 Gene3D G3DSA:3.30.420.140 1 127 4.1E-28 T 11-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 TO73_0303 30452c8dce4d5a0365ad755f18d61351 128 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 1 124 2.9E-17 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TO73_0303 30452c8dce4d5a0365ad755f18d61351 128 SUPERFAMILY SSF53098 1 125 2.28E-24 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_0303 30452c8dce4d5a0365ad755f18d61351 128 Pfam PF03652 Holliday junction resolvase 1 125 6.7E-28 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TO73_0303 30452c8dce4d5a0365ad755f18d61351 128 SMART SM00732 1 93 8.5E-10 T 11-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 222 8.2E-24 T 11-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 Gene3D G3DSA:2.170.120.12 50 171 1.0E-90 T 11-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 SUPERFAMILY SSF55257 3 227 1.37E-31 T 11-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 SUPERFAMILY SSF56553 50 172 7.06E-41 T 11-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 262 314 8.0E-22 T 11-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 1.4E-98 T 11-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 306 1.8E-16 T 11-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 154 8.3E-26 T 11-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 2 314 33.092 T 11-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 Gene3D G3DSA:1.10.150.20 247 314 7.6E-21 T 11-10-2018 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 SMART SM00662 20 228 2.6E-102 T 11-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 SUPERFAMILY SSF47789 251 313 3.66E-14 T 11-10-2018 TO73_0404 e2844f2c5fca01ba22142e6bea1a138b 314 Gene3D G3DSA:3.30.1360.10 19 222 1.0E-90 T 11-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0676 eaa5498a0c851d5fd16e4d5bf57a310a 144 Gene3D G3DSA:1.10.10.10 7 141 2.3E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0676 eaa5498a0c851d5fd16e4d5bf57a310a 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 8.1E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TO73_0676 eaa5498a0c851d5fd16e4d5bf57a310a 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 8.1E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TO73_0676 eaa5498a0c851d5fd16e4d5bf57a310a 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 8.1E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TO73_0676 eaa5498a0c851d5fd16e4d5bf57a310a 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 8.1E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TO73_0676 eaa5498a0c851d5fd16e4d5bf57a310a 144 Pfam PF13463 Winged helix DNA-binding domain 39 101 2.5E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TO73_0676 eaa5498a0c851d5fd16e4d5bf57a310a 144 SUPERFAMILY SSF46785 7 140 8.65E-31 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0676 eaa5498a0c851d5fd16e4d5bf57a310a 144 SMART SM00347 29 128 2.0E-18 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TO73_0676 eaa5498a0c851d5fd16e4d5bf57a310a 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TO73_0217 932465cfbd3c66d61471f1959f0b31c5 186 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 63 3.7E-12 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TO73_0217 932465cfbd3c66d61471f1959f0b31c5 186 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 186 30.346 T 11-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TO73_0217 932465cfbd3c66d61471f1959f0b31c5 186 Pfam PF01467 Cytidylyltransferase-like 5 160 1.5E-27 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TO73_0217 932465cfbd3c66d61471f1959f0b31c5 186 Gene3D G3DSA:3.40.50.620 1 186 2.8E-56 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0217 932465cfbd3c66d61471f1959f0b31c5 186 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 5 185 1.4E-47 T 11-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TO73_0217 932465cfbd3c66d61471f1959f0b31c5 186 SUPERFAMILY SSF52374 3 186 6.82E-49 T 11-10-2018 TO73_2377 d9989de74c7685dd96ab4eb8bd426f47 219 Gene3D G3DSA:3.30.465.10 1 114 1.3E-34 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TO73_2377 d9989de74c7685dd96ab4eb8bd426f47 219 SUPERFAMILY SSF56176 2 113 6.54E-17 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TO73_2377 d9989de74c7685dd96ab4eb8bd426f47 219 Gene3D G3DSA:3.30.70.2560 115 169 1.3E-29 T 11-10-2018 TO73_2377 d9989de74c7685dd96ab4eb8bd426f47 219 Pfam PF01565 FAD binding domain 3 77 3.7E-5 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TO73_0856 fbf878a0b792bb22cc6f555fcb4784fa 417 Pfam PF07282 Putative transposase DNA-binding domain 297 365 2.2E-18 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_0856 fbf878a0b792bb22cc6f555fcb4784fa 417 Pfam PF12323 Helix-turn-helix domain 2 45 2.7E-13 T 11-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain TO73_0856 fbf878a0b792bb22cc6f555fcb4784fa 417 Pfam PF01385 Probable transposase 170 284 1.7E-23 T 11-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TO73_0856 fbf878a0b792bb22cc6f555fcb4784fa 417 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 252 324 1.6E-11 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_1237 8b445edc8c09a8a3a405008efc98c4c2 559 Gene3D G3DSA:3.30.565.10 425 556 1.6E-32 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1237 8b445edc8c09a8a3a405008efc98c4c2 559 SMART SM00387 464 557 1.5E-8 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1237 8b445edc8c09a8a3a405008efc98c4c2 559 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 554 6.1E-8 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1237 8b445edc8c09a8a3a405008efc98c4c2 559 SUPERFAMILY SSF55781 222 357 2.23E-5 T 11-10-2018 TO73_1237 8b445edc8c09a8a3a405008efc98c4c2 559 Pfam PF07730 Histidine kinase 370 427 1.3E-12 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TO73_1237 8b445edc8c09a8a3a405008efc98c4c2 559 SUPERFAMILY SSF55874 429 555 7.99E-22 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_0661 9946b2b21cf6ec6e8031ce893114688c 277 Gene3D G3DSA:3.40.50.300 14 256 3.7E-54 T 11-10-2018 TO73_0661 9946b2b21cf6ec6e8031ce893114688c 277 Pfam PF00005 ABC transporter 33 182 3.1E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0661 9946b2b21cf6ec6e8031ce893114688c 277 SUPERFAMILY SSF52540 16 254 2.93E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0661 9946b2b21cf6ec6e8031ce893114688c 277 SMART SM00382 42 247 3.3E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0661 9946b2b21cf6ec6e8031ce893114688c 277 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1015 8ab07eb8f342bf6d3fa3f43af9de3c1b 232 SUPERFAMILY SSF63965 21 220 4.45E-68 T 11-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 TO73_1015 8ab07eb8f342bf6d3fa3f43af9de3c1b 232 Pfam PF02570 Precorrin-8X methylmutase 22 216 8.7E-72 T 11-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 TO73_1015 8ab07eb8f342bf6d3fa3f43af9de3c1b 232 Gene3D G3DSA:3.40.50.10230 15 232 1.7E-88 T 11-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 Pfam PF00436 Single-strand binding protein family 5 105 2.3E-25 T 11-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 Pfam PF00436 Single-strand binding protein family 128 228 3.8E-25 T 11-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 SUPERFAMILY SSF50249 128 267 7.43E-31 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 Hamap MF_00984 Single-stranded DNA-binding protein. 128 234 24.09 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 Hamap MF_00984 Single-stranded DNA-binding protein. 5 111 23.391 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 Gene3D G3DSA:2.40.50.140 1 126 7.0E-43 T 11-10-2018 TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 125 227 6.8E-26 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 111 7.1E-27 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 SUPERFAMILY SSF50249 3 121 6.28E-31 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0127 98550f6c9f5f01a14cdedb858c756357 267 Gene3D G3DSA:2.40.50.140 127 238 2.3E-38 T 11-10-2018 TO73_0060 9b18868ceb4b7b411e7ad5f0ae2dd13a 244 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 16 238 6.9E-66 T 11-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase TO73_0060 9b18868ceb4b7b411e7ad5f0ae2dd13a 244 SUPERFAMILY SSF64438 8 239 1.21E-72 T 11-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic TO73_0060 9b18868ceb4b7b411e7ad5f0ae2dd13a 244 Gene3D G3DSA:3.60.140.10 4 241 6.1E-75 T 11-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily TO73_0060 9b18868ceb4b7b411e7ad5f0ae2dd13a 244 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 21 239 1.1E-44 T 11-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase TO73_1186 478618126652fdb078f086fd5fc076fe 179 Pfam PF11985 Protein of unknown function (DUF3486) 9 178 5.1E-17 T 11-10-2018 IPR021874 Bacteriophage Mu, Gp27 TO73_1784 4e3522a9158ff9b82561ef2416ddc05b 231 Pfam PF03741 Integral membrane protein TerC family 12 182 4.6E-49 T 11-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TO73_1784 4e3522a9158ff9b82561ef2416ddc05b 231 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 8 222 3.3E-68 T 11-10-2018 IPR022493 Integral membrane YkoY TO73_1081 a7f5cc25f3ff5102fc8b71206751c83c 122 SUPERFAMILY SSF55298 1 118 1.1E-45 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TO73_1081 a7f5cc25f3ff5102fc8b71206751c83c 122 PIRSF PIRSF005965 1 122 1.1E-47 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TO73_1081 a7f5cc25f3ff5102fc8b71206751c83c 122 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 2 118 4.6E-41 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TO73_1081 a7f5cc25f3ff5102fc8b71206751c83c 122 Gene3D G3DSA:3.30.1330.40 1 122 1.8E-52 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TO73_1081 a7f5cc25f3ff5102fc8b71206751c83c 122 Pfam PF07736 Chorismate mutase type I 2 118 1.3E-44 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TO73_1081 a7f5cc25f3ff5102fc8b71206751c83c 122 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 8 121 3.0E-58 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TO73_2510 fa3cf24d71cdb7bdaaba862088bf3e34 354 SUPERFAMILY SSF53098 182 338 1.09E-26 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2510 fa3cf24d71cdb7bdaaba862088bf3e34 354 SUPERFAMILY SSF46689 42 140 7.17E-14 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_2510 fa3cf24d71cdb7bdaaba862088bf3e34 354 Pfam PF13384 Homeodomain-like domain 31 80 1.2E-12 T 11-10-2018 TO73_2510 fa3cf24d71cdb7bdaaba862088bf3e34 354 Pfam PF13683 Integrase core domain 266 331 1.9E-18 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 TO73_2510 fa3cf24d71cdb7bdaaba862088bf3e34 354 Gene3D G3DSA:3.30.420.10 181 346 6.3E-14 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_1529 15ceef84d0c29e5e44782e23cdae2202 213 Gene3D G3DSA:3.40.50.360 1 201 1.7E-33 T 11-10-2018 IPR029039 Flavoprotein-like superfamily TO73_1529 15ceef84d0c29e5e44782e23cdae2202 213 Pfam PF03358 NADPH-dependent FMN reductase 1 157 2.1E-26 T 11-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TO73_1529 15ceef84d0c29e5e44782e23cdae2202 213 SUPERFAMILY SSF52218 1 188 8.54E-39 T 11-10-2018 IPR029039 Flavoprotein-like superfamily TO73_0655 7256a688800d3a6f42f7b6ad206e5ec3 48 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 11-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0655 7256a688800d3a6f42f7b6ad206e5ec3 48 Pfam PF00468 Ribosomal protein L34 1 43 4.4E-23 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0655 7256a688800d3a6f42f7b6ad206e5ec3 48 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 25 2.0E-7 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0655 7256a688800d3a6f42f7b6ad206e5ec3 48 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 43 1.0E-20 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0655 7256a688800d3a6f42f7b6ad206e5ec3 48 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.628 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_2108 857db423b1161a970c4502e540b0d83f 155 Gene3D G3DSA:1.20.120.20 13 136 8.5E-9 T 11-10-2018 TO73_2108 857db423b1161a970c4502e540b0d83f 155 SUPERFAMILY SSF58113 11 135 2.75E-9 T 11-10-2018 TO73_2108 857db423b1161a970c4502e540b0d83f 155 Pfam PF07798 Protein of unknown function (DUF1640) 29 150 1.8E-7 T 11-10-2018 IPR024461 Coiled-coil domain-containing protein 90-like TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 SUPERFAMILY SSF54211 186 311 1.86E-17 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 SMART SM00853 342 467 1.0E-21 T 11-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 SMART SM01340 196 312 1.4E-24 T 11-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 SUPERFAMILY SSF118116 338 509 1.57E-34 T 11-10-2018 IPR037198 MutL, C-terminal domain superfamily TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 507 20.447 T 11-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 21 113 1.1E-9 T 11-10-2018 TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 Gene3D G3DSA:3.30.565.10 1 189 2.2E-37 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 Gene3D G3DSA:3.30.1370.100 384 464 5.9E-37 T 11-10-2018 TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 Gene3D G3DSA:2.30.42.20 343 509 5.9E-37 T 11-10-2018 TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 Gene3D G3DSA:3.30.230.10 206 319 2.2E-13 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 Pfam PF08676 MutL C terminal dimerisation domain 340 467 2.6E-18 T 11-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 SUPERFAMILY SSF55874 2 189 2.88E-33 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_0610 cfabdf342a5415e40dff0ef76c68b928 532 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 198 309 1.2E-15 T 11-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 Gene3D G3DSA:3.30.450.90 478 612 3.6E-39 T 11-10-2018 TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 SUPERFAMILY SSF160246 166 299 1.18E-23 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 707 721 - T 11-10-2018 IPR001482 Type II/IV secretion system protein TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 SUPERFAMILY SSF160246 8 147 1.28E-33 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 Gene3D G3DSA:3.30.300.160 391 476 2.2E-9 T 11-10-2018 TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 Gene3D G3DSA:3.30.300.160 65 147 1.4E-5 T 11-10-2018 TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 Pfam PF00437 Type II/IV secretion system protein 516 779 2.2E-75 T 11-10-2018 IPR001482 Type II/IV secretion system protein TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 SUPERFAMILY SSF160246 332 476 2.09E-36 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 Gene3D G3DSA:3.40.50.300 614 889 5.3E-126 T 11-10-2018 TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 369 479 3.7E-22 T 11-10-2018 IPR007831 General secretory system II, protein E, N-terminal TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 201 303 6.7E-14 T 11-10-2018 IPR007831 General secretory system II, protein E, N-terminal TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 44 148 4.9E-19 T 11-10-2018 IPR007831 General secretory system II, protein E, N-terminal TO73_0058 5806b6f3f84b77a5b6bd37ee5a4b61ee 889 SUPERFAMILY SSF52540 503 885 2.15E-96 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2119 5d6ce26df6a83103bc7b4eff653cd18a 240 SUPERFAMILY SSF56300 2 239 2.31E-47 T 11-10-2018 TO73_2119 5d6ce26df6a83103bc7b4eff653cd18a 240 Gene3D G3DSA:3.60.21.10 1 240 7.2E-53 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like TO73_2119 5d6ce26df6a83103bc7b4eff653cd18a 240 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 201 2.4E-18 T 11-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TO73_2119 5d6ce26df6a83103bc7b4eff653cd18a 240 PIRSF PIRSF000883 1 240 6.1E-44 T 11-10-2018 IPR011152 Phosphoesterase MJ0912 TO73_1537 0540b2c301223fd1ed4ad923e8a4e2c5 131 Gene3D G3DSA:1.20.1300.10 12 125 1.1E-21 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1537 0540b2c301223fd1ed4ad923e8a4e2c5 131 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 13 114 4.3E-16 T 11-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1537 0540b2c301223fd1ed4ad923e8a4e2c5 131 SUPERFAMILY SSF81343 17 126 1.57E-24 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_2802 7b3fcfd6f7d67a912cda2e43596aefa7 1024 Gene3D G3DSA:3.40.50.300 266 379 1.1E-17 T 11-10-2018 TO73_2802 7b3fcfd6f7d67a912cda2e43596aefa7 1024 SUPERFAMILY SSF52540 288 392 4.81E-20 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2802 7b3fcfd6f7d67a912cda2e43596aefa7 1024 Pfam PF09369 Domain of unknown function (DUF1998) 800 882 3.2E-5 T 11-10-2018 IPR018973 DEAD/DEAH-box helicase, putative TO73_2802 7b3fcfd6f7d67a912cda2e43596aefa7 1024 Pfam PF00271 Helicase conserved C-terminal domain 288 362 2.5E-10 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_2802 7b3fcfd6f7d67a912cda2e43596aefa7 1024 Gene3D G3DSA:3.40.960.10 926 1023 1.4E-8 T 11-10-2018 TO73_2802 7b3fcfd6f7d67a912cda2e43596aefa7 1024 SMART SM00490 276 362 3.7E-15 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_1456 8c855f319c7f27db1aaa29e6ac9dee2f 627 Pfam PF13188 PAS domain 142 191 1.1E-5 T 11-10-2018 IPR000014 PAS domain TO73_1456 8c855f319c7f27db1aaa29e6ac9dee2f 627 SMART SM00479 442 604 2.6E-47 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TO73_1456 8c855f319c7f27db1aaa29e6ac9dee2f 627 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 442 599 3.1E-31 T 11-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TO73_1456 8c855f319c7f27db1aaa29e6ac9dee2f 627 SUPERFAMILY SSF53098 442 611 5.79E-51 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_1456 8c855f319c7f27db1aaa29e6ac9dee2f 627 Pfam PF00929 Exonuclease 445 595 7.4E-30 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TO73_1456 8c855f319c7f27db1aaa29e6ac9dee2f 627 Gene3D G3DSA:3.30.420.10 442 600 3.0E-48 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_1456 8c855f319c7f27db1aaa29e6ac9dee2f 627 SUPERFAMILY SSF55785 130 200 3.29E-6 T 11-10-2018 IPR035965 PAS domain superfamily TO73_1456 8c855f319c7f27db1aaa29e6ac9dee2f 627 SMART SM00091 140 204 0.0019 T 11-10-2018 IPR000014 PAS domain TO73_0142 39960d672a604e2ad45ac9d946f77a24 141 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 4 121 3.5E-33 T 11-10-2018 IPR018699 Protein of unknown function DUF2203 TO73_0142 39960d672a604e2ad45ac9d946f77a24 141 PIRSF PIRSF016498 2 127 4.6E-24 T 11-10-2018 IPR018699 Protein of unknown function DUF2203 TO73_1316 a6e0f814f0595bd2ae9524dacc1d2552 262 Gene3D G3DSA:2.40.10.350 172 247 9.3E-28 T 11-10-2018 TO73_1316 a6e0f814f0595bd2ae9524dacc1d2552 262 Gene3D G3DSA:2.40.10.340 113 258 9.3E-28 T 11-10-2018 TO73_1316 a6e0f814f0595bd2ae9524dacc1d2552 262 PIRSF PIRSF038471 2 262 5.6E-38 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 TO73_1316 a6e0f814f0595bd2ae9524dacc1d2552 262 Pfam PF04085 rod shape-determining protein MreC 115 259 1.3E-29 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 TO73_0475 397b2c59a9504d817fc45608de7de66f 142 Pfam PF02577 Bifunctional nuclease 5 130 5.1E-45 T 11-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 TO73_0475 397b2c59a9504d817fc45608de7de66f 142 SUPERFAMILY SSF103256 6 131 5.49E-42 T 11-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 TO73_0475 397b2c59a9504d817fc45608de7de66f 142 Gene3D G3DSA:3.10.690.10 1 136 4.5E-48 T 11-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 TO73_2110 a424a273b0d87030bfbcca9777463b75 564 Gene3D G3DSA:1.10.1370.20 202 563 3.5E-106 T 11-10-2018 TO73_2110 a424a273b0d87030bfbcca9777463b75 564 Pfam PF08439 Oligopeptidase F 105 159 1.4E-4 T 11-10-2018 IPR013647 Oligopeptidase F, N-terminal domain TO73_2110 a424a273b0d87030bfbcca9777463b75 564 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 5 560 7.4E-185 T 11-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 TO73_2110 a424a273b0d87030bfbcca9777463b75 564 SUPERFAMILY SSF55486 43 561 6.35E-78 T 11-10-2018 TO73_2110 a424a273b0d87030bfbcca9777463b75 564 Pfam PF01432 Peptidase family M3 313 548 3.3E-21 T 11-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 TO73_1857 f74583e105310ba08fd26126eddfac67 321 Pfam PF01171 PP-loop family 50 221 1.1E-9 T 11-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TO73_1857 f74583e105310ba08fd26126eddfac67 321 SUPERFAMILY SSF52402 25 243 2.65E-40 T 11-10-2018 TO73_1857 f74583e105310ba08fd26126eddfac67 321 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 193 293 5.3E-20 T 11-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TO73_1857 f74583e105310ba08fd26126eddfac67 321 Gene3D G3DSA:3.40.50.620 1 310 4.5E-73 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1857 f74583e105310ba08fd26126eddfac67 321 PIRSF PIRSF004976 1 303 7.4E-82 T 11-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TO73_0425 bf349e653743c4f1e7f92f3f39de829e 355 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 100 340 1.1E-74 T 11-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 TO73_0425 bf349e653743c4f1e7f92f3f39de829e 355 Pfam PF08486 Stage II sporulation protein 96 183 1.4E-26 T 11-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 Pfam PF01568 Molydopterin dinucleotide binding domain 547 658 2.4E-25 T 11-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 SMART SM00926 1 53 8.5E-12 T 11-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 Gene3D G3DSA:3.40.50.740 65 475 1.5E-133 T 11-10-2018 TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 SUPERFAMILY SSF50692 543 664 8.91E-34 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 2 51 4.5E-10 T 11-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 Gene3D G3DSA:2.20.25.90 1 54 1.4E-7 T 11-10-2018 TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 Gene3D G3DSA:3.40.228.10 131 520 1.5E-133 T 11-10-2018 TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 Pfam PF00384 Molybdopterin oxidoreductase 54 471 1.1E-62 T 11-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 Gene3D G3DSA:3.30.2070.10 430 518 1.5E-133 T 11-10-2018 TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 Gene3D G3DSA:2.40.40.20 543 666 3.5E-27 T 11-10-2018 TO73_2183 355fb1c24ecb34543fa922a5ce64ac6b 667 SUPERFAMILY SSF53706 2 561 3.4E-154 T 11-10-2018 TO73_0426 7fea3677041ac38db54ac6702584f88a 147 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 70 145 7.5E-22 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TO73_0426 7fea3677041ac38db54ac6702584f88a 147 Gene3D G3DSA:1.10.10.10 66 147 1.6E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0426 7fea3677041ac38db54ac6702584f88a 147 SUPERFAMILY SSF53155 2 65 4.12E-5 T 11-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TO73_0426 7fea3677041ac38db54ac6702584f88a 147 SUPERFAMILY SSF46767 68 145 1.7E-22 T 11-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TO73_0426 7fea3677041ac38db54ac6702584f88a 147 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 69 144 3.4E-19 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TO73_1733 2812c113f3961e17af555c261ef097ac 154 Pfam PF00578 AhpC/TSA family 3 130 1.2E-41 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TO73_1733 2812c113f3961e17af555c261ef097ac 154 SUPERFAMILY SSF52833 2 150 9.73E-55 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1733 2812c113f3961e17af555c261ef097ac 154 PIRSF PIRSF000239 2 153 5.4E-27 T 11-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TO73_1733 2812c113f3961e17af555c261ef097ac 154 Gene3D G3DSA:3.40.30.10 3 152 3.3E-54 T 11-10-2018 TO73_0252 351a55f0b46118d4dbda3d4efda12ca0 196 Pfam PF14522 Cytochrome c7 and related cytochrome c 106 196 3.7E-7 T 11-10-2018 IPR029467 C-type polyheme cytochrome OmcB TO73_0252 351a55f0b46118d4dbda3d4efda12ca0 196 Gene3D G3DSA:3.90.10.10 6 95 1.4E-9 T 11-10-2018 TO73_0252 351a55f0b46118d4dbda3d4efda12ca0 196 SUPERFAMILY SSF48695 24 169 4.4E-43 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily TO73_1833 0b707ad45da312e4d75274ed969bbeb1 130 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 129 12.206 T 11-10-2018 IPR022907 VapC family GO:0004540 TO73_1833 0b707ad45da312e4d75274ed969bbeb1 130 Gene3D G3DSA:3.40.50.1010 1 127 6.3E-40 T 11-10-2018 TO73_1833 0b707ad45da312e4d75274ed969bbeb1 130 Pfam PF01850 PIN domain 1 124 6.3E-16 T 11-10-2018 IPR002716 PIN domain TO73_1833 0b707ad45da312e4d75274ed969bbeb1 130 SUPERFAMILY SSF88723 1 127 2.85E-20 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_2414 e9ce72867d1e9d328874698e3cb88265 272 Pfam PF07136 Protein of unknown function (DUF1385) 37 266 2.1E-74 T 11-10-2018 IPR010787 Protein of unknown function DUF1385 TO73_2414 e9ce72867d1e9d328874698e3cb88265 272 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 37 267 4.0E-85 T 11-10-2018 IPR010787 Protein of unknown function DUF1385 TO73_0041 5ef44452d1d3f8ec7be96a33ba7dad11 603 SUPERFAMILY SSF109998 330 462 6.28E-9 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily TO73_0041 5ef44452d1d3f8ec7be96a33ba7dad11 603 Pfam PF13145 PPIC-type PPIASE domain 160 290 1.1E-21 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 TO73_0041 5ef44452d1d3f8ec7be96a33ba7dad11 603 Pfam PF13145 PPIC-type PPIASE domain 419 543 1.7E-14 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 TO73_0041 5ef44452d1d3f8ec7be96a33ba7dad11 603 Gene3D G3DSA:3.10.50.40 180 278 8.7E-30 T 11-10-2018 TO73_0041 5ef44452d1d3f8ec7be96a33ba7dad11 603 SUPERFAMILY SSF54534 181 276 8.63E-15 T 11-10-2018 TO73_0041 5ef44452d1d3f8ec7be96a33ba7dad11 603 Gene3D G3DSA:1.10.4030.30 76 290 8.7E-30 T 11-10-2018 TO73_0041 5ef44452d1d3f8ec7be96a33ba7dad11 603 SUPERFAMILY SSF109998 39 209 1.84E-20 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily TO73_0041 5ef44452d1d3f8ec7be96a33ba7dad11 603 Pfam PF13624 SurA N-terminal domain 8 149 4.3E-10 T 11-10-2018 TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 Gene3D G3DSA:3.30.420.40 3 302 3.7E-106 T 11-10-2018 TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 293 2.1E-92 T 11-10-2018 IPR017861 Kae1/TsaD family TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 74 94 1.0E-47 T 11-10-2018 IPR017861 Kae1/TsaD family TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 95 114 1.0E-47 T 11-10-2018 IPR017861 Kae1/TsaD family TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 127 139 1.0E-47 T 11-10-2018 IPR017861 Kae1/TsaD family TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 254 263 1.0E-47 T 11-10-2018 IPR017861 Kae1/TsaD family TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.0E-47 T 11-10-2018 IPR017861 Kae1/TsaD family TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 150 171 1.0E-47 T 11-10-2018 IPR017861 Kae1/TsaD family TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 Gene3D G3DSA:3.30.420.40 125 280 3.7E-106 T 11-10-2018 TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 300 2.7E-109 T 11-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 319 61.388 T 11-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 Pfam PF00814 Glycoprotease family 23 293 7.4E-91 T 11-10-2018 IPR000905 Gcp-like domain TO73_1760 8b56d5d1d51f65a34d9de28d4fbd7397 322 SUPERFAMILY SSF53067 1 297 1.92E-34 T 11-10-2018 TO73_1455 debbe186f798d6e5d74d693fb3001812 118 Pfam PF00072 Response regulator receiver domain 3 111 3.2E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1455 debbe186f798d6e5d74d693fb3001812 118 SMART SM00448 1 111 7.4E-36 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1455 debbe186f798d6e5d74d693fb3001812 118 Gene3D G3DSA:3.40.50.12740 1 117 1.1E-35 T 11-10-2018 TO73_1455 debbe186f798d6e5d74d693fb3001812 118 SUPERFAMILY SSF52172 1 115 1.85E-35 T 11-10-2018 IPR011006 CheY-like superfamily TO73_1014 4b4dc1fefc6c660794497bba161cae98 404 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 5 201 9.9E-51 T 11-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 TO73_1014 4b4dc1fefc6c660794497bba161cae98 404 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 181 5.8E-28 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TO73_1014 4b4dc1fefc6c660794497bba161cae98 404 SUPERFAMILY SSF53335 217 368 9.79E-27 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1014 4b4dc1fefc6c660794497bba161cae98 404 SUPERFAMILY SSF53790 3 202 1.19E-38 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TO73_1014 4b4dc1fefc6c660794497bba161cae98 404 Gene3D G3DSA:3.40.50.150 210 404 3.0E-69 T 11-10-2018 TO73_1014 4b4dc1fefc6c660794497bba161cae98 404 Gene3D G3DSA:3.40.1010.10 1 101 1.2E-18 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TO73_1014 4b4dc1fefc6c660794497bba161cae98 404 PIRSF PIRSF036428 1 403 4.2E-107 T 11-10-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00860+2.1.1.132 TO73_1014 4b4dc1fefc6c660794497bba161cae98 404 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 230 351 5.5E-38 T 11-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 Gene3D G3DSA:2.60.120.380 411 505 3.9E-5 T 11-10-2018 TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 Gene3D G3DSA:3.30.70.80 37 115 8.1E-17 T 11-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 SUPERFAMILY SSF52743 123 386 2.49E-79 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 155 166 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 Pfam PF00082 Subtilase family 150 377 1.7E-35 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 340 350 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 190 200 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 Pfam PF05922 Peptidase inhibitor I9 47 118 9.2E-6 T 11-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 SUPERFAMILY SSF54897 44 119 1.13E-12 T 11-10-2018 TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 Gene3D G3DSA:3.40.50.200 121 396 1.2E-101 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 PRINTS PR00723 Subtilisin serine protease family (S8) signature 150 169 2.1E-20 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 199 2.1E-20 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_1716 a964465088e907ec6ffffc8e283ee99c 506 PRINTS PR00723 Subtilisin serine protease family (S8) signature 339 355 2.1E-20 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_1026 345d0dc631aa82b7822dfc24c9adfbcb 514 Gene3D G3DSA:1.20.140.10 261 421 4.7E-33 T 11-10-2018 TO73_1026 345d0dc631aa82b7822dfc24c9adfbcb 514 SUPERFAMILY SSF47203 260 423 5.15E-33 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_1026 345d0dc631aa82b7822dfc24c9adfbcb 514 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_1026 345d0dc631aa82b7822dfc24c9adfbcb 514 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 151 249 2.5E-16 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TO73_1026 345d0dc631aa82b7822dfc24c9adfbcb 514 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 261 419 1.3E-35 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TO73_1026 345d0dc631aa82b7822dfc24c9adfbcb 514 Gene3D G3DSA:2.40.110.20 114 260 5.1E-27 T 11-10-2018 TO73_1026 345d0dc631aa82b7822dfc24c9adfbcb 514 SUPERFAMILY SSF56645 86 270 4.32E-32 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_0504 fdb9a47a21226c7d6c968c06cea51dc8 128 Gene3D G3DSA:3.30.230.10 1 128 6.3E-53 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0504 fdb9a47a21226c7d6c968c06cea51dc8 128 ProSitePatterns PS00360 Ribosomal protein S9 signature. 67 85 - T 11-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TO73_0504 fdb9a47a21226c7d6c968c06cea51dc8 128 SUPERFAMILY SSF54211 3 128 9.36E-46 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0504 fdb9a47a21226c7d6c968c06cea51dc8 128 Pfam PF00380 Ribosomal protein S9/S16 8 128 8.6E-43 T 11-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TO73_0504 fdb9a47a21226c7d6c968c06cea51dc8 128 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 128 31.382 T 11-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 SMART SM00487 1 176 4.3E-15 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 15 753 4.8E-185 T 11-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 Gene3D G3DSA:1.20.120.1080 345 442 4.9E-9 T 11-10-2018 TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 SUPERFAMILY SSF52540 10 321 4.86E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 Gene3D G3DSA:3.40.50.300 2 169 2.3E-43 T 11-10-2018 TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 Gene3D G3DSA:3.40.50.300 170 326 6.8E-45 T 11-10-2018 TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 SMART SM00490 216 310 9.0E-16 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 110 119 - T 11-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 Pfam PF00270 DEAD/DEAH box helicase 5 156 3.9E-9 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 Pfam PF08482 ATP-dependent helicase C-terminal 622 753 2.8E-46 T 11-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 SMART SM00847 365 454 3.4E-8 T 11-10-2018 IPR007502 Helicase-associated domain GO:0004386 TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 Pfam PF00271 Helicase conserved C-terminal domain 200 310 3.4E-13 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_2039 b7c243b6ca1ed3a3da1261fb6d10a798 753 Pfam PF04408 Helicase associated domain (HA2) 366 422 1.3E-11 T 11-10-2018 IPR007502 Helicase-associated domain GO:0004386 TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 Gene3D G3DSA:3.10.580.10 294 358 3.4E-8 T 11-10-2018 TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 SUPERFAMILY SSF54631 238 353 1.11E-23 T 11-10-2018 TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 Pfam PF00571 CBS domain 307 353 3.0E-7 T 11-10-2018 IPR000644 CBS domain TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 Pfam PF00571 CBS domain 243 289 3.4E-10 T 11-10-2018 IPR000644 CBS domain TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 Pfam PF02163 Peptidase family M50 66 135 2.6E-7 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 Pfam PF02163 Peptidase family M50 145 195 1.0E-7 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 PIRSF PIRSF006404 2 361 3.3E-110 T 11-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 SMART SM00116 307 354 8.9E-4 T 11-10-2018 IPR000644 CBS domain TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 SMART SM00116 250 297 0.1 T 11-10-2018 IPR000644 CBS domain TO73_0617 ee6fa09160ebe2d7dc33c7d22439d21e 370 Gene3D G3DSA:3.10.580.10 177 293 6.3E-11 T 11-10-2018 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Pfam PF04851 Type III restriction enzyme, res subunit 250 472 8.6E-6 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Pfam PF00929 Exonuclease 8 169 8.9E-12 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 SUPERFAMILY SSF53098 7 177 3.0E-32 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Gene3D G3DSA:3.40.50.300 248 519 8.0E-35 T 11-10-2018 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 980 1370 3.3E-94 T 11-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 SUPERFAMILY SSF52540 262 881 7.53E-19 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Gene3D G3DSA:3.40.50.300 937 1160 6.1E-60 T 11-10-2018 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Pfam PF00271 Helicase conserved C-terminal domain 1186 1296 1.3E-14 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Gene3D G3DSA:3.40.50.300 726 910 1.0E-13 T 11-10-2018 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 SMART SM00490 1214 1297 4.5E-25 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 SUPERFAMILY SSF52540 1017 1313 4.59E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Gene3D G3DSA:3.40.50.300 1166 1381 1.2E-41 T 11-10-2018 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Gene3D G3DSA:1.10.10.10 1488 1680 2.4E-18 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Gene3D G3DSA:3.30.420.10 3 178 1.6E-30 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 SMART SM00487 974 1175 4.2E-27 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 SMART SM00487 245 512 0.0021 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 SMART SM00479 6 179 3.1E-17 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Pfam PF13307 Helicase C-terminal domain 756 907 5.9E-17 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Pfam PF16124 RecQ zinc-binding 1496 1544 2.5E-9 T 11-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 Pfam PF00270 DEAD/DEAH box helicase 982 1149 4.2E-21 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TO73_2817 e3698ecee75c1429f0e9eefb15667705 1684 SMART SM00491 764 894 0.0012 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TO73_0258 d2dd1328cdf641ac02c17b92861d7d27 536 Pfam PF00990 Diguanylate cyclase, GGDEF domain 375 532 3.7E-40 T 11-10-2018 IPR000160 GGDEF domain TO73_0258 d2dd1328cdf641ac02c17b92861d7d27 536 SMART SM00267 364 536 9.4E-57 T 11-10-2018 IPR000160 GGDEF domain TO73_0258 d2dd1328cdf641ac02c17b92861d7d27 536 SUPERFAMILY SSF55073 380 534 2.75E-42 T 11-10-2018 IPR029787 Nucleotide cyclase TO73_0258 d2dd1328cdf641ac02c17b92861d7d27 536 Gene3D G3DSA:3.30.70.270 370 536 1.1E-50 T 11-10-2018 TO73_0258 d2dd1328cdf641ac02c17b92861d7d27 536 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 374 535 5.4E-44 T 11-10-2018 IPR000160 GGDEF domain TO73_2031 a08b0a096afd238e4e0a086f2bd16833 307 PIRSF PIRSF000196 3 306 2.9E-106 T 11-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 TO73_2031 a08b0a096afd238e4e0a086f2bd16833 307 Gene3D G3DSA:3.20.20.530 19 307 1.6E-90 T 11-10-2018 TO73_2031 a08b0a096afd238e4e0a086f2bd16833 307 Pfam PF01619 Proline dehydrogenase 45 292 1.8E-26 T 11-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 TO73_2031 a08b0a096afd238e4e0a086f2bd16833 307 SUPERFAMILY SSF51730 38 302 5.49E-66 T 11-10-2018 IPR029041 FAD-linked oxidoreductase-like TO73_2294 b1c7e7f0542f69285045fbe554261117 419 Gene3D G3DSA:1.10.8.60 149 216 1.9E-14 T 11-10-2018 TO73_2294 b1c7e7f0542f69285045fbe554261117 419 Gene3D G3DSA:1.10.3710.10 320 416 6.0E-27 T 11-10-2018 TO73_2294 b1c7e7f0542f69285045fbe554261117 419 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 41 141 4.3E-16 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_2294 b1c7e7f0542f69285045fbe554261117 419 Pfam PF12002 MgsA AAA+ ATPase C terminal 241 406 5.5E-61 T 11-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal TO73_2294 b1c7e7f0542f69285045fbe554261117 419 Gene3D G3DSA:3.40.50.300 1 147 8.8E-40 T 11-10-2018 TO73_2294 b1c7e7f0542f69285045fbe554261117 419 Pfam PF16193 AAA C-terminal domain 171 240 4.8E-19 T 11-10-2018 IPR032423 AAA C-terminal domain TO73_2294 b1c7e7f0542f69285045fbe554261117 419 SUPERFAMILY SSF48019 226 409 1.74E-66 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TO73_2294 b1c7e7f0542f69285045fbe554261117 419 Gene3D G3DSA:1.20.272.10 217 319 1.2E-39 T 11-10-2018 TO73_2294 b1c7e7f0542f69285045fbe554261117 419 SUPERFAMILY SSF52540 2 214 5.07E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2294 b1c7e7f0542f69285045fbe554261117 419 SMART SM00382 37 149 2.2E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0437 0b9cbae18d5ca0fe65580534f1f2477c 407 Pfam PF00464 Serine hydroxymethyltransferase 7 381 9.9E-172 T 11-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TO73_0437 0b9cbae18d5ca0fe65580534f1f2477c 407 SUPERFAMILY SSF53383 7 407 1.28E-178 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_0437 0b9cbae18d5ca0fe65580534f1f2477c 407 Gene3D G3DSA:3.40.640.10 33 284 5.3E-187 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_0437 0b9cbae18d5ca0fe65580534f1f2477c 407 PIRSF PIRSF000412 4 404 4.2E-172 T 11-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TO73_0437 0b9cbae18d5ca0fe65580534f1f2477c 407 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 11-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TO73_0437 0b9cbae18d5ca0fe65580534f1f2477c 407 Gene3D G3DSA:3.90.1150.10 8 387 5.3E-187 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_0437 0b9cbae18d5ca0fe65580534f1f2477c 407 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 406 52.557 T 11-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TO73_2338 f5344e5d4eae8749ebf0e4e1c04aa3a9 373 Pfam PF00155 Aminotransferase class I and II 22 368 1.4E-76 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TO73_2338 f5344e5d4eae8749ebf0e4e1c04aa3a9 373 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 221 234 - T 11-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TO73_2338 f5344e5d4eae8749ebf0e4e1c04aa3a9 373 SUPERFAMILY SSF53383 2 372 1.84E-117 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_2338 f5344e5d4eae8749ebf0e4e1c04aa3a9 373 Gene3D G3DSA:3.40.640.10 53 271 2.0E-158 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_2338 f5344e5d4eae8749ebf0e4e1c04aa3a9 373 Gene3D G3DSA:3.90.1150.10 14 367 2.0E-158 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 PIRSF PIRSF006205 1 367 7.4E-127 T 11-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 Gene3D G3DSA:3.40.50.720 1 138 1.7E-36 T 11-10-2018 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 364 1.3E-110 T 11-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 Pfam PF13288 DXP reductoisomerase C-terminal domain 248 361 9.5E-36 T 11-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 134 216 3.6E-34 T 11-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 366 41.513 T 11-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 SUPERFAMILY SSF51735 2 138 3.33E-33 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 SUPERFAMILY SSF69055 280 366 6.28E-25 T 11-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 SUPERFAMILY SSF55347 114 250 1.47E-50 T 11-10-2018 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 120 3.2E-27 T 11-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TO73_1685 eb0c4f9e987bbe17ab95e26d7d7e4c37 367 Gene3D G3DSA:1.10.1740.10 287 367 4.0E-24 T 11-10-2018 TO73_0348 d5456748863747c044e31ce23a4c4147 69 SMART SM00704 21 58 1.2E-8 T 11-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TO73_0348 d5456748863747c044e31ce23a4c4147 69 PIRSF PIRSF037159 1 69 1.7E-43 T 11-10-2018 IPR017123 Uncharacterised conserved protein UCP037159 TO73_0348 d5456748863747c044e31ce23a4c4147 69 Pfam PF09360 Iron-binding zinc finger CDGSH type 8 53 7.7E-16 T 11-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TO73_0348 d5456748863747c044e31ce23a4c4147 69 Gene3D G3DSA:3.40.5.90 1 66 6.4E-19 T 11-10-2018 TO73_1275 5612001a1af767881fa98a597511b6a8 62 SUPERFAMILY SSF161098 3 62 2.94E-11 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1354 744dc3e00daa1e394f443a1755d2d915 253 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TO73_1354 744dc3e00daa1e394f443a1755d2d915 253 SUPERFAMILY SSF52096 4 253 9.39E-81 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_1354 744dc3e00daa1e394f443a1755d2d915 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 253 5.7E-57 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TO73_1354 744dc3e00daa1e394f443a1755d2d915 253 Gene3D G3DSA:3.90.226.10 1 198 1.3E-75 T 11-10-2018 TO73_1354 744dc3e00daa1e394f443a1755d2d915 253 Gene3D G3DSA:1.10.12.10 199 253 1.4E-26 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TO73_0933 ef65fe6110320511e75a4aa62b590054 398 Gene3D G3DSA:3.40.50.2300 34 349 2.4E-67 T 11-10-2018 TO73_0933 ef65fe6110320511e75a4aa62b590054 398 Gene3D G3DSA:3.40.50.2300 146 275 2.4E-67 T 11-10-2018 TO73_0933 ef65fe6110320511e75a4aa62b590054 398 SUPERFAMILY SSF53822 28 353 6.73E-67 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_0933 ef65fe6110320511e75a4aa62b590054 398 Pfam PF13458 Periplasmic binding protein 27 352 1.2E-59 T 11-10-2018 IPR028081 Leucine-binding protein domain TO73_1018 45a3833142f3575aafd526526b02677a 400 Gene3D G3DSA:3.40.47.10 6 281 3.7E-175 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1018 45a3833142f3575aafd526526b02677a 400 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TO73_1018 45a3833142f3575aafd526526b02677a 400 Pfam PF02803 Thiolase, C-terminal domain 276 398 1.2E-48 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TO73_1018 45a3833142f3575aafd526526b02677a 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 4.7E-148 T 11-10-2018 IPR002155 Thiolase GO:0016747 TO73_1018 45a3833142f3575aafd526526b02677a 400 SUPERFAMILY SSF53901 276 398 3.63E-47 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1018 45a3833142f3575aafd526526b02677a 400 PIRSF PIRSF000429 1 400 1.4E-144 T 11-10-2018 IPR002155 Thiolase GO:0016747 TO73_1018 45a3833142f3575aafd526526b02677a 400 Pfam PF00108 Thiolase, N-terminal domain 6 267 7.1E-83 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TO73_1018 45a3833142f3575aafd526526b02677a 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 11-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 TO73_1018 45a3833142f3575aafd526526b02677a 400 Gene3D G3DSA:3.40.47.10 141 397 3.7E-175 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1018 45a3833142f3575aafd526526b02677a 400 SUPERFAMILY SSF53901 3 275 2.28E-89 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1018 45a3833142f3575aafd526526b02677a 400 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 TO73_0598 b0555f90b539dedbec842df54e2ded5f 501 Gene3D G3DSA:3.40.190.10 177 485 9.0E-146 T 11-10-2018 TO73_0598 b0555f90b539dedbec842df54e2ded5f 501 Gene3D G3DSA:3.10.105.10 251 475 9.0E-146 T 11-10-2018 TO73_0598 b0555f90b539dedbec842df54e2ded5f 501 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 61 419 3.8E-94 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain TO73_0598 b0555f90b539dedbec842df54e2ded5f 501 PIRSF PIRSF002741 16 500 1.1E-107 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TO73_0598 b0555f90b539dedbec842df54e2ded5f 501 SUPERFAMILY SSF53850 19 500 1.28E-142 T 11-10-2018 TO73_0598 b0555f90b539dedbec842df54e2ded5f 501 Gene3D G3DSA:3.90.76.10 28 176 9.0E-146 T 11-10-2018 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 Gene3D G3DSA:3.40.50.720 189 424 1.2E-87 T 11-10-2018 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 SMART SM00839 191 421 6.4E-99 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 PIRSF PIRSF000185 15 424 1.2E-160 T 11-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 Gene3D G3DSA:1.10.8.1210 4 47 3.4E-18 T 11-10-2018 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 189 421 1.8E-73 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 SUPERFAMILY SSF53223 14 191 4.48E-69 T 11-10-2018 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 SUPERFAMILY SSF51735 189 423 7.46E-76 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0416 ca7cd0528971884000902d3c748e14d0 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 180 202 1.2E-32 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 349 360 1.2E-32 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 100 114 1.2E-32 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 222 242 1.2E-32 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 108 121 - T 11-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 43 171 9.8E-55 T 11-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TO73_0416 ca7cd0528971884000902d3c748e14d0 424 Gene3D G3DSA:3.40.50.10860 48 188 9.2E-64 T 11-10-2018 TO73_1755 b53cb48081fa8197668e2b46ed88984a 374 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 26 231 1.5E-43 T 11-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TO73_1755 b53cb48081fa8197668e2b46ed88984a 374 SUPERFAMILY SSF53822 32 238 6.6E-11 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_0624 18831714f7926e55f8453b349f607f06 357 SMART SM00729 118 338 1.6E-20 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_0624 18831714f7926e55f8453b349f607f06 357 Pfam PF04055 Radical SAM superfamily 124 284 1.2E-8 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_0624 18831714f7926e55f8453b349f607f06 357 SUPERFAMILY SSF102114 86 340 6.54E-23 T 11-10-2018 TO73_0624 18831714f7926e55f8453b349f607f06 357 Gene3D G3DSA:3.20.20.70 64 346 5.0E-10 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_2355 673832d17d000db3f833d09c86aaca96 260 Pfam PF03631 Virulence factor BrkB 11 258 9.3E-29 T 11-10-2018 IPR017039 Virulence factor BrkB TO73_2355 673832d17d000db3f833d09c86aaca96 260 PIRSF PIRSF035875 1 260 3.9E-32 T 11-10-2018 IPR017039 Virulence factor BrkB TO73_1508 2f69474251cd66bee20ace70af9d16ec 570 SUPERFAMILY SSF55486 38 568 5.63E-92 T 11-10-2018 TO73_1508 2f69474251cd66bee20ace70af9d16ec 570 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 2 569 1.9E-193 T 11-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 TO73_1508 2f69474251cd66bee20ace70af9d16ec 570 Gene3D G3DSA:1.10.1370.30 19 569 6.8E-120 T 11-10-2018 TO73_1508 2f69474251cd66bee20ace70af9d16ec 570 Pfam PF08439 Oligopeptidase F 103 168 3.7E-16 T 11-10-2018 IPR013647 Oligopeptidase F, N-terminal domain TO73_1508 2f69474251cd66bee20ace70af9d16ec 570 Pfam PF01432 Peptidase family M3 183 555 6.7E-34 T 11-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 TO73_1612 d6d50161c559fc956cea6a294eff46eb 274 Gene3D G3DSA:3.30.200.20 1 83 3.6E-12 T 11-10-2018 TO73_1612 d6d50161c559fc956cea6a294eff46eb 274 SUPERFAMILY SSF56112 3 252 1.09E-55 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily TO73_1612 d6d50161c559fc956cea6a294eff46eb 274 Pfam PF00069 Protein kinase domain 8 247 4.7E-37 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TO73_1612 d6d50161c559fc956cea6a294eff46eb 274 SMART SM00220 6 253 3.3E-36 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TO73_1612 d6d50161c559fc956cea6a294eff46eb 274 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 12 38 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TO73_1612 d6d50161c559fc956cea6a294eff46eb 274 Gene3D G3DSA:1.10.510.10 87 264 6.0E-40 T 11-10-2018 TO73_1612 d6d50161c559fc956cea6a294eff46eb 274 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 123 135 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TO73_2326 67ebedeba8f800915295f47af6db68ca 145 Gene3D G3DSA:3.40.50.1010 4 134 1.4E-8 T 11-10-2018 TO73_2326 67ebedeba8f800915295f47af6db68ca 145 SUPERFAMILY SSF88723 3 128 3.69E-11 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_2326 67ebedeba8f800915295f47af6db68ca 145 Pfam PF01850 PIN domain 3 107 5.7E-8 T 11-10-2018 IPR002716 PIN domain TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.7E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.7E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.7E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.7E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.7E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.7E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 251 4.9E-57 T 11-10-2018 TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 183 0.0019 T 11-10-2018 TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 SUPERFAMILY SSF51735 9 252 2.2E-77 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.2E-10 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 5.2E-10 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.2E-10 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0924 27d9809e92efaccfb73c4a70b83339ee 253 Gene3D G3DSA:3.40.50.720 1 253 9.6E-78 T 11-10-2018 TO73_0325 b60a7b5dcad8cbddb31e7575fa0ceb38 192 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 183 1.5E-40 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal TO73_0325 b60a7b5dcad8cbddb31e7575fa0ceb38 192 SMART SM01007 7 184 3.3E-46 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal TO73_0325 b60a7b5dcad8cbddb31e7575fa0ceb38 192 Gene3D G3DSA:3.40.225.10 1 192 8.9E-73 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TO73_0325 b60a7b5dcad8cbddb31e7575fa0ceb38 192 SUPERFAMILY SSF53639 13 187 5.1E-42 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 Gene3D G3DSA:1.20.58.1480 120 244 2.4E-36 T 11-10-2018 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 679 687 - T 11-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 PIRSF PIRSF001174 1 778 1.2E-301 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 Gene3D G3DSA:1.10.8.60 495 587 6.1E-23 T 11-10-2018 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 SUPERFAMILY SSF52540 316 593 8.43E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 199 5.2E-36 T 11-10-2018 IPR003111 Lon, substrate-binding domain TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 598 614 4.9E-51 T 11-10-2018 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 676 695 4.9E-51 T 11-10-2018 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 359 378 4.9E-51 T 11-10-2018 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 729 747 4.9E-51 T 11-10-2018 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 706 725 4.9E-51 T 11-10-2018 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 Gene3D G3DSA:2.30.130.40 1 113 4.2E-31 T 11-10-2018 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 TIGRFAM TIGR00763 lon: endopeptidase La 9 773 4.4E-280 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 Hamap MF_01973 Lon protease [lon]. 8 775 70.087 T 11-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 SUPERFAMILY SSF54211 598 773 2.69E-56 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 Gene3D G3DSA:3.40.50.300 314 494 8.2E-65 T 11-10-2018 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 Gene3D G3DSA:3.30.230.10 596 777 3.9E-78 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 SUPERFAMILY SSF88697 7 199 7.7E-40 T 11-10-2018 IPR015947 PUA-like superfamily TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 355 492 8.3E-21 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 SMART SM00382 351 496 6.4E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 SMART SM00464 7 201 2.0E-56 T 11-10-2018 IPR003111 Lon, substrate-binding domain TO73_1496 f11d74260e6bf51e0a85337611b0bdeb 794 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 573 774 4.6E-93 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 Pfam PF07549 SecD/SecF GG Motif 32 50 0.0039 T 11-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 Pfam PF07549 SecD/SecF GG Motif 466 489 3.9E-7 T 11-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 Gene3D G3DSA:3.30.70.3400 48 258 4.7E-82 T 11-10-2018 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 Gene3D G3DSA:3.30.1360.200 112 252 4.7E-82 T 11-10-2018 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 442 729 26.987 T 11-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 35 422 1.5E-126 T 11-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 184 414 2.1E-65 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 551 715 5.2E-55 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 SUPERFAMILY SSF82866 231 426 1.44E-36 T 11-10-2018 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 Gene3D G3DSA:3.30.70.2040 477 561 2.1E-39 T 11-10-2018 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 470 717 3.9E-74 T 11-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 Pfam PF02355 Protein export membrane protein 551 727 2.0E-64 T 11-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 Pfam PF02355 Protein export membrane protein 255 426 6.5E-16 T 11-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 434 38.592 T 11-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 SUPERFAMILY SSF82866 547 728 1.57E-40 T 11-10-2018 TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 PRINTS PR01755 Bacterial translocase SecF protein signature 634 652 2.3E-28 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 PRINTS PR01755 Bacterial translocase SecF protein signature 666 681 2.3E-28 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 PRINTS PR01755 Bacterial translocase SecF protein signature 469 484 2.3E-28 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TO73_0685 a16c22e104f47ae88fdaf2ac4a81f5a5 736 PRINTS PR01755 Bacterial translocase SecF protein signature 586 600 2.3E-28 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TO73_1358 29763b73d63447fcd78cb1f8227d9849 235 SUPERFAMILY SSF55174 2 64 3.68E-13 T 11-10-2018 TO73_1358 29763b73d63447fcd78cb1f8227d9849 235 Pfam PF01479 S4 domain 1 46 9.5E-15 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_1358 29763b73d63447fcd78cb1f8227d9849 235 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 2 227 2.3E-62 T 11-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 TO73_1358 29763b73d63447fcd78cb1f8227d9849 235 Gene3D G3DSA:3.10.290.10 1 58 2.8E-20 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TO73_1358 29763b73d63447fcd78cb1f8227d9849 235 SMART SM00363 1 63 5.6E-15 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_1358 29763b73d63447fcd78cb1f8227d9849 235 SUPERFAMILY SSF53335 49 233 2.21E-26 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1358 29763b73d63447fcd78cb1f8227d9849 235 Pfam PF01728 FtsJ-like methyltransferase 56 231 2.7E-18 T 11-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 TO73_1358 29763b73d63447fcd78cb1f8227d9849 235 Gene3D G3DSA:3.40.50.150 59 235 7.5E-65 T 11-10-2018 TO73_1358 29763b73d63447fcd78cb1f8227d9849 235 PIRSF PIRSF005578 1 235 1.2E-86 T 11-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 TO73_2212 9db5a8bfb5f92eed7e27d460d1a94201 390 Pfam PF07690 Major Facilitator Superfamily 7 294 1.2E-36 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_2212 9db5a8bfb5f92eed7e27d460d1a94201 390 PRINTS PR01035 Tetracycline resistance protein signature 13 29 1.4E-12 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TO73_2212 9db5a8bfb5f92eed7e27d460d1a94201 390 PRINTS PR01035 Tetracycline resistance protein signature 336 359 1.4E-12 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TO73_2212 9db5a8bfb5f92eed7e27d460d1a94201 390 PRINTS PR01035 Tetracycline resistance protein signature 249 269 1.4E-12 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TO73_2212 9db5a8bfb5f92eed7e27d460d1a94201 390 PRINTS PR01035 Tetracycline resistance protein signature 139 161 1.4E-12 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TO73_2212 9db5a8bfb5f92eed7e27d460d1a94201 390 SUPERFAMILY SSF103473 4 388 5.75E-49 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_2212 9db5a8bfb5f92eed7e27d460d1a94201 390 Gene3D G3DSA:1.20.1250.20 4 382 5.3E-53 T 11-10-2018 TO73_1884 1abac39d7581a9fa4be3636bf41e566d 467 SUPERFAMILY SSF53448 60 371 3.66E-53 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1884 1abac39d7581a9fa4be3636bf41e566d 467 Gene3D G3DSA:3.90.550.10 48 315 1.2E-43 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1884 1abac39d7581a9fa4be3636bf41e566d 467 Pfam PF13641 Glycosyltransferase like family 2 61 325 3.6E-29 T 11-10-2018 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 2.5E-31 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 48 66 2.5E-31 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 72 90 2.5E-31 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 114 133 2.5E-31 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 140 1.0E-51 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 3 145 2.0E-51 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 SUPERFAMILY SSF63411 4 148 4.85E-55 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 152 36.265 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 PIRSF PIRSF006160 1 151 1.0E-58 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_1805 91963f0702d3db3f9b12dc738b451942 152 Gene3D G3DSA:3.30.1360.80 1 152 1.9E-55 T 11-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_0584 a4b688ac8643e48e78b5d1d925767ac5 103 Gene3D G3DSA:3.30.70.120 1 103 3.8E-43 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TO73_0584 a4b688ac8643e48e78b5d1d925767ac5 103 Pfam PF03091 CutA1 divalent ion tolerance protein 4 100 5.6E-39 T 11-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TO73_0584 a4b688ac8643e48e78b5d1d925767ac5 103 SUPERFAMILY SSF54913 4 102 1.33E-38 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TO73_0323 894d8741e336e67a5f356911931dee42 1119 Gene3D G3DSA:2.40.50.150 707 834 0.0 T 11-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 SUPERFAMILY SSF64484 4 1113 0.0 T 11-10-2018 TO73_0323 894d8741e336e67a5f356911931dee42 1119 ProSitePatterns PS01166 RNA polymerases beta chain signature. 836 848 - T 11-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Gene3D G3DSA:2.40.50.100 597 671 0.0 T 11-10-2018 TO73_0323 894d8741e336e67a5f356911931dee42 1119 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 231 808 1.3E-252 T 11-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Gene3D G3DSA:3.90.1100.10 9 596 0.0 T 11-10-2018 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Pfam PF10385 RNA polymerase beta subunit external 1 domain 471 535 7.4E-24 T 11-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Gene3D G3DSA:2.30.150.10 474 539 0.0 T 11-10-2018 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Pfam PF04561 RNA polymerase Rpb2, domain 2 142 334 4.4E-11 T 11-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Gene3D G3DSA:2.40.270.10 7 1004 0.0 T 11-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Gene3D G3DSA:3.90.1110.10 147 328 0.0 T 11-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Pfam PF04560 RNA polymerase Rpb2, domain 7 1028 1102 1.8E-26 T 11-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 4 1104 11.804 T 11-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Pfam PF00562 RNA polymerase Rpb2, domain 6 597 1026 2.0E-148 T 11-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Pfam PF04563 RNA polymerase beta subunit 18 379 8.6E-40 T 11-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Gene3D G3DSA:3.90.1800.10 1014 1067 1.5E-10 T 11-10-2018 TO73_0323 894d8741e336e67a5f356911931dee42 1119 Pfam PF04565 RNA polymerase Rpb2, domain 3 393 461 4.1E-29 T 11-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_2228 04f53fbdd8b814b0c0470ecc8fe30214 391 Pfam PF00589 Phage integrase family 186 368 9.6E-30 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TO73_2228 04f53fbdd8b814b0c0470ecc8fe30214 391 Gene3D G3DSA:1.10.443.10 184 381 1.2E-48 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TO73_2228 04f53fbdd8b814b0c0470ecc8fe30214 391 Gene3D G3DSA:1.10.150.130 64 183 5.8E-17 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal TO73_2228 04f53fbdd8b814b0c0470ecc8fe30214 391 SUPERFAMILY SSF56349 70 373 5.3E-62 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TO73_0357 44f32729c9776f0e18058ca41ce57e31 342 Pfam PF01207 Dihydrouridine synthase (Dus) 8 310 7.5E-72 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TO73_0357 44f32729c9776f0e18058ca41ce57e31 342 Gene3D G3DSA:1.20.120.1460 244 318 2.9E-34 T 11-10-2018 TO73_0357 44f32729c9776f0e18058ca41ce57e31 342 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 87 105 - T 11-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 TO73_0357 44f32729c9776f0e18058ca41ce57e31 342 SUPERFAMILY SSF51395 5 310 2.01E-69 T 11-10-2018 TO73_0357 44f32729c9776f0e18058ca41ce57e31 342 PIRSF PIRSF006621 1 326 9.9E-67 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TO73_0357 44f32729c9776f0e18058ca41ce57e31 342 Gene3D G3DSA:3.20.20.70 3 243 4.0E-79 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0357 44f32729c9776f0e18058ca41ce57e31 342 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 314 43.446 T 11-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 TO73_0343 b039fc0241c2695f1b5e3e38dfcd2851 491 Pfam PF04055 Radical SAM superfamily 168 319 3.8E-16 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_0343 b039fc0241c2695f1b5e3e38dfcd2851 491 SUPERFAMILY SSF102114 157 459 2.35E-45 T 11-10-2018 TO73_0343 b039fc0241c2695f1b5e3e38dfcd2851 491 Gene3D G3DSA:3.20.20.70 156 451 1.6E-41 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 378 29.032 T 11-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 SMART SM00316 143 208 1.3E-13 T 11-10-2018 IPR022967 RNA-binding domain, S1 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 SUPERFAMILY SSF54814 211 287 9.59E-30 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 Pfam PF13184 NusA-like KH domain 240 307 7.5E-29 T 11-10-2018 IPR025249 KH domain, NusA-like GO:0003723 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 Gene3D G3DSA:3.30.300.20 288 384 8.6E-26 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 350 1.2E-124 T 11-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 Gene3D G3DSA:2.40.50.140 145 208 1.7E-23 T 11-10-2018 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 SUPERFAMILY SSF69705 1 136 4.84E-33 T 11-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 SUPERFAMILY SSF50249 141 209 5.06E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 Pfam PF00575 S1 RNA binding domain 141 205 5.5E-12 T 11-10-2018 IPR003029 S1 domain GO:0003676 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 SMART SM00322 311 372 2.2E-4 T 11-10-2018 IPR004087 K Homology domain GO:0003676 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 SMART SM00322 240 303 13.0 T 11-10-2018 IPR004087 K Homology domain GO:0003676 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 Gene3D G3DSA:3.30.1480.10 1 138 5.7E-37 T 11-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 Pfam PF08529 NusA N-terminal domain 4 134 6.0E-32 T 11-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 SUPERFAMILY SSF54814 289 350 3.92E-13 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TO73_0689 2f30e7429f9352cd71a0d6db6be734cb 385 Gene3D G3DSA:3.30.300.20 209 287 1.9E-34 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_1076 7c0efbfa7a06480c2fc5b7647557cb5d 369 SUPERFAMILY SSF51604 113 364 8.12E-66 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TO73_1076 7c0efbfa7a06480c2fc5b7647557cb5d 369 SUPERFAMILY SSF54826 1 125 2.8E-33 T 11-10-2018 TO73_1076 7c0efbfa7a06480c2fc5b7647557cb5d 369 SMART SM00922 142 234 1.5E-20 T 11-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TO73_1076 7c0efbfa7a06480c2fc5b7647557cb5d 369 Pfam PF13378 Enolase C-terminal domain-like 150 352 1.6E-42 T 11-10-2018 IPR029065 Enolase C-terminal domain-like TO73_1076 7c0efbfa7a06480c2fc5b7647557cb5d 369 Gene3D G3DSA:3.30.390.10 7 350 4.1E-142 T 11-10-2018 IPR029017 Enolase-like, N-terminal TO73_1076 7c0efbfa7a06480c2fc5b7647557cb5d 369 Gene3D G3DSA:3.20.20.120 117 346 4.1E-142 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TO73_1076 7c0efbfa7a06480c2fc5b7647557cb5d 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 124 2.2E-10 T 11-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TO73_1076 7c0efbfa7a06480c2fc5b7647557cb5d 369 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 41.659 T 11-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 TO73_1076 7c0efbfa7a06480c2fc5b7647557cb5d 369 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 12 330 1.0E-99 T 11-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 TO73_2048 9dfeaedca78547527314a85631222222 227 Pfam PF00106 short chain dehydrogenase 5 188 6.7E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2048 9dfeaedca78547527314a85631222222 227 SUPERFAMILY SSF51735 2 215 2.94E-39 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_2048 9dfeaedca78547527314a85631222222 227 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 183 0.0018 T 11-10-2018 TO73_2048 9dfeaedca78547527314a85631222222 227 Gene3D G3DSA:3.40.50.720 1 220 2.6E-39 T 11-10-2018 TO73_0178 9088072e7feefcac840154bede2ba59f 542 Pfam PF13245 AAA domain 10 230 6.0E-21 T 11-10-2018 TO73_0178 9088072e7feefcac840154bede2ba59f 542 SUPERFAMILY SSF52540 8 524 3.77E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0178 9088072e7feefcac840154bede2ba59f 542 Gene3D G3DSA:3.40.50.300 4 108 4.2E-13 T 11-10-2018 TO73_0178 9088072e7feefcac840154bede2ba59f 542 Pfam PF13538 UvrD-like helicase C-terminal domain 467 518 6.3E-12 T 11-10-2018 IPR027785 UvrD-like helicase C-terminal domain TO73_0178 9088072e7feefcac840154bede2ba59f 542 Gene3D G3DSA:3.40.50.300 443 535 3.0E-10 T 11-10-2018 TO73_0178 9088072e7feefcac840154bede2ba59f 542 Gene3D G3DSA:3.40.50.300 154 269 1.2E-13 T 11-10-2018 TO73_0321 d328326dce3022ca2eec95d2c6684b72 143 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 137 8.0E-50 T 11-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TO73_0321 d328326dce3022ca2eec95d2c6684b72 143 SUPERFAMILY SSF54637 3 139 8.02E-44 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_0321 d328326dce3022ca2eec95d2c6684b72 143 Pfam PF07977 FabA-like domain 10 128 3.1E-29 T 11-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TO73_0321 d328326dce3022ca2eec95d2c6684b72 143 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 1 140 31.472 T 11-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TO73_0321 d328326dce3022ca2eec95d2c6684b72 143 Gene3D G3DSA:3.10.129.10 1 140 1.3E-51 T 11-10-2018 TO73_2831 2e212038c74312d404b5cf524c734aff 105 SUPERFAMILY SSF54909 2 99 1.64E-28 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel TO73_2831 2e212038c74312d404b5cf524c734aff 105 Pfam PF03992 Antibiotic biosynthesis monooxygenase 2 76 5.7E-19 T 11-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TO73_2831 2e212038c74312d404b5cf524c734aff 105 Gene3D G3DSA:3.30.70.100 1 105 2.7E-36 T 11-10-2018 TO73_0441 44bab3bbda0d1346bda2e961d5b13441 237 Gene3D G3DSA:3.40.50.1000 4 204 2.0E-32 T 11-10-2018 IPR023214 HAD superfamily TO73_0441 44bab3bbda0d1346bda2e961d5b13441 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 122 203 5.7E-9 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0441 44bab3bbda0d1346bda2e961d5b13441 237 Gene3D G3DSA:1.10.150.400 16 106 2.0E-32 T 11-10-2018 TO73_0441 44bab3bbda0d1346bda2e961d5b13441 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 91 204 4.3E-12 T 11-10-2018 TO73_0441 44bab3bbda0d1346bda2e961d5b13441 237 SUPERFAMILY SSF56784 2 236 5.72E-32 T 11-10-2018 IPR036412 HAD-like superfamily TO73_0345 4710d0479dc19c5eeded6d8c4765f742 198 SUPERFAMILY SSF103473 2 181 1.02E-14 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_0345 4710d0479dc19c5eeded6d8c4765f742 198 Gene3D G3DSA:1.20.1250.20 1 191 3.5E-9 T 11-10-2018 TO73_1535 7dc91100f6d6725ef7e78bd89e47134b 232 SUPERFAMILY SSF46548 103 228 8.37E-32 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TO73_1535 7dc91100f6d6725ef7e78bd89e47134b 232 SUPERFAMILY SSF54292 1 102 1.43E-31 T 11-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TO73_1535 7dc91100f6d6725ef7e78bd89e47134b 232 Gene3D G3DSA:1.10.1060.10 103 230 7.7E-46 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TO73_1535 7dc91100f6d6725ef7e78bd89e47134b 232 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 107 1.5E-35 T 11-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1535 7dc91100f6d6725ef7e78bd89e47134b 232 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 224 6.8E-79 T 11-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1535 7dc91100f6d6725ef7e78bd89e47134b 232 Pfam PF13237 4Fe-4S dicluster domain 142 211 4.5E-10 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_1535 7dc91100f6d6725ef7e78bd89e47134b 232 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_1535 7dc91100f6d6725ef7e78bd89e47134b 232 Gene3D G3DSA:3.10.20.30 1 102 1.5E-34 T 11-10-2018 IPR012675 Beta-grasp domain superfamily TO73_0112 62f89c5b39bbed953929fb065db4465f 167 Pfam PF11159 Protein of unknown function (DUF2939) 19 108 4.2E-24 T 11-10-2018 IPR021330 Protein of unknown function DUF2939 TO73_2024 2593efc457bc621b3ec7d091329ab91b 294 SUPERFAMILY SSF51430 6 293 1.44E-77 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TO73_2024 2593efc457bc621b3ec7d091329ab91b 294 Pfam PF00248 Aldo/keto reductase family 8 293 9.1E-61 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain TO73_2024 2593efc457bc621b3ec7d091329ab91b 294 PRINTS PR00069 Aldo-keto reductase signature 98 116 9.9E-8 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TO73_2024 2593efc457bc621b3ec7d091329ab91b 294 PRINTS PR00069 Aldo-keto reductase signature 129 146 9.9E-8 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TO73_2024 2593efc457bc621b3ec7d091329ab91b 294 Gene3D G3DSA:3.20.20.100 4 294 5.7E-80 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TO73_1600 b9b04c006badb8196a929e7c33a5ac09 104 Pfam PF16999 Vacuolar (H+)-ATPase G subunit 1 104 1.1E-30 T 11-10-2018 TO73_2165 6a3f33ba6da61b8a110aa4208ab744c3 112 SUPERFAMILY SSF53146 3 79 4.06E-17 T 11-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TO73_2165 6a3f33ba6da61b8a110aa4208ab744c3 112 Gene3D G3DSA:3.30.420.130 3 110 6.9E-13 T 11-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TO73_2165 6a3f33ba6da61b8a110aa4208ab744c3 112 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 21 72 6.9E-10 T 11-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TO73_0837 f54662f267be693960bfbe435388dc85 489 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0837 f54662f267be693960bfbe435388dc85 489 SMART SM00382 274 465 16.0 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0837 f54662f267be693960bfbe435388dc85 489 SMART SM00382 26 212 2.6E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0837 f54662f267be693960bfbe435388dc85 489 Gene3D G3DSA:3.40.50.300 1 241 2.6E-61 T 11-10-2018 TO73_0837 f54662f267be693960bfbe435388dc85 489 SUPERFAMILY SSF52540 249 475 6.38E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0837 f54662f267be693960bfbe435388dc85 489 Pfam PF00005 ABC transporter 266 412 9.4E-13 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0837 f54662f267be693960bfbe435388dc85 489 Pfam PF00005 ABC transporter 19 164 4.1E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0837 f54662f267be693960bfbe435388dc85 489 SUPERFAMILY SSF52540 2 222 3.66E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0837 f54662f267be693960bfbe435388dc85 489 Gene3D G3DSA:3.40.50.300 263 486 1.7E-33 T 11-10-2018 TO73_2268 0bdde0217501969ad3260ab4d0ee3495 220 Gene3D G3DSA:2.40.50.580 2 71 1.1E-14 T 11-10-2018 TO73_2268 0bdde0217501969ad3260ab4d0ee3495 220 Gene3D G3DSA:3.40.1350.60 73 215 1.3E-32 T 11-10-2018 TO73_2268 0bdde0217501969ad3260ab4d0ee3495 220 Pfam PF03749 Sugar fermentation stimulation protein 14 206 6.9E-45 T 11-10-2018 IPR005224 Sugar fermentation stimulation protein TO73_1160 fa6a87129ee1488c9ebe41518f8e07ed 471 ProSitePatterns PS00571 Amidases signature. 139 170 - T 11-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TO73_1160 fa6a87129ee1488c9ebe41518f8e07ed 471 SUPERFAMILY SSF75304 3 458 4.84E-156 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TO73_1160 fa6a87129ee1488c9ebe41518f8e07ed 471 Gene3D G3DSA:3.90.1300.10 1 471 8.9E-208 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TO73_1160 fa6a87129ee1488c9ebe41518f8e07ed 471 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 6 459 87.243 T 11-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TO73_1160 fa6a87129ee1488c9ebe41518f8e07ed 471 Pfam PF01425 Amidase 19 448 2.6E-141 T 11-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TO73_1160 fa6a87129ee1488c9ebe41518f8e07ed 471 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 7 457 1.5E-159 T 11-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 SUPERFAMILY SSF53738 4 163 2.88E-43 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 364 433 5.0E-15 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 Gene3D G3DSA:3.40.120.10 170 352 4.4E-58 T 11-10-2018 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 250 2.7E-12 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 Gene3D G3DSA:3.40.120.10 4 151 1.2E-47 T 11-10-2018 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 SUPERFAMILY SSF53738 155 252 2.51E-24 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 4 433 43.115 T 11-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 8 431 1.9E-166 T 11-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 Gene3D G3DSA:3.40.120.10 253 330 4.4E-58 T 11-10-2018 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 Gene3D G3DSA:3.30.310.50 361 435 1.6E-24 T 11-10-2018 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 SUPERFAMILY SSF55957 349 433 2.88E-23 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 255 357 1.3E-29 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 230 245 5.9E-10 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 5.9E-10 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 5.9E-10 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 SUPERFAMILY SSF53738 255 356 7.85E-28 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0714 7ea1c53353a3822c0bfb669fcf2cb47e 436 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 138 1.0E-43 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 303 3.6E-32 T 11-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 SUPERFAMILY SSF143548 314 443 1.15E-24 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 Gene3D G3DSA:3.30.70.260 448 521 6.2E-23 T 11-10-2018 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 Gene3D G3DSA:3.40.50.720 22 302 1.1E-111 T 11-10-2018 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 SUPERFAMILY SSF52283 23 123 1.57E-32 T 11-10-2018 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TO73_0953 e7354f4722881c0eea3e13394bb42996 521 Gene3D G3DSA:3.40.50.720 94 276 1.1E-111 T 11-10-2018 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 SUPERFAMILY SSF55021 439 516 1.57E-17 T 11-10-2018 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 188 210 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TO73_0953 e7354f4722881c0eea3e13394bb42996 521 Gene3D G3DSA:3.30.1330.90 315 447 5.6E-27 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 139 166 - T 11-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 Pfam PF01842 ACT domain 448 511 5.5E-14 T 11-10-2018 IPR002912 ACT domain TO73_0953 e7354f4722881c0eea3e13394bb42996 521 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 278 7.6E-61 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TO73_0953 e7354f4722881c0eea3e13394bb42996 521 SUPERFAMILY SSF51735 97 279 5.0E-58 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0953 e7354f4722881c0eea3e13394bb42996 521 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 520 4.7E-181 T 11-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 TO73_0735 ad99c03e1c15d5edac4d939a693fa5e0 105 Gene3D G3DSA:1.10.287.10 17 105 2.2E-38 T 11-10-2018 TO73_0735 ad99c03e1c15d5edac4d939a693fa5e0 105 Pfam PF00312 Ribosomal protein S15 24 104 2.1E-37 T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0735 ad99c03e1c15d5edac4d939a693fa5e0 105 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 26 104 2.0E-17 T 11-10-2018 TO73_0735 ad99c03e1c15d5edac4d939a693fa5e0 105 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 20 105 2.6E-37 T 11-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0735 ad99c03e1c15d5edac4d939a693fa5e0 105 ProSitePatterns PS00362 Ribosomal protein S15 signature. 55 85 - T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0735 ad99c03e1c15d5edac4d939a693fa5e0 105 SUPERFAMILY SSF47060 19 105 3.24E-35 T 11-10-2018 IPR009068 S15/NS1, RNA-binding TO73_0735 ad99c03e1c15d5edac4d939a693fa5e0 105 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 19 105 23.029 T 11-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0735 ad99c03e1c15d5edac4d939a693fa5e0 105 SMART SM01387 24 104 6.7E-51 T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 SMART SM00322 565 629 5.7E-13 T 11-10-2018 IPR004087 K Homology domain GO:0003676 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Gene3D G3DSA:3.30.1370.10 563 633 1.5E-17 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 SUPERFAMILY SSF55666 463 560 7.85E-27 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 10 705 29.911 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 18 702 6.7E-297 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 258 332 3.2E-6 T 11-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 SUPERFAMILY SSF54211 306 500 6.07E-52 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Gene3D G3DSA:3.30.230.70 4 235 2.6E-83 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Pfam PF03725 3' exoribonuclease family, domain 2 153 216 2.2E-18 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Pfam PF03725 3' exoribonuclease family, domain 2 472 541 7.4E-7 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 SMART SM00316 632 702 1.2E-26 T 11-10-2018 IPR022967 RNA-binding domain, S1 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Pfam PF00013 KH domain 570 626 3.4E-11 T 11-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 SUPERFAMILY SSF50249 621 699 5.74E-20 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0734 dda0015f7fdad86269a012df1e587b30 713 SUPERFAMILY SSF55666 151 242 1.06E-29 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Gene3D G3DSA:2.40.50.140 634 704 1.7E-25 T 11-10-2018 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Pfam PF01138 3' exoribonuclease family, domain 1 21 150 3.7E-21 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Pfam PF01138 3' exoribonuclease family, domain 1 336 469 4.1E-25 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 SUPERFAMILY SSF54211 14 150 5.57E-47 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0734 dda0015f7fdad86269a012df1e587b30 713 SUPERFAMILY SSF54791 565 641 1.14E-14 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Gene3D G3DSA:3.30.230.70 246 562 1.4E-113 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 Pfam PF00575 S1 RNA binding domain 631 699 3.4E-17 T 11-10-2018 IPR003029 S1 domain GO:0003676 TO73_0734 dda0015f7fdad86269a012df1e587b30 713 PIRSF PIRSF005499 10 712 2.3E-290 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 11-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 427 2.4E-134 T 11-10-2018 TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 Pfam PF00919 Uncharacterized protein family UPF0004 2 100 4.3E-25 T 11-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 Gene3D G3DSA:3.80.30.20 137 369 4.6E-87 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 423 8.1E-144 T 11-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 Pfam PF04055 Radical SAM superfamily 142 312 5.1E-33 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 SMART SM00729 138 355 2.2E-63 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 427 65.026 T 11-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 Gene3D G3DSA:3.40.50.12160 1 127 3.6E-27 T 11-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TO73_1500 bfe0b93bde5fc5fc8599dcc1d98e8982 440 SUPERFAMILY SSF102114 117 365 1.12E-66 T 11-10-2018 TO73_0595 93a17bb889107d143a5af5085b00466b 347 Pfam PF14343 PrcB C-terminal 272 326 5.3E-14 T 11-10-2018 IPR025748 PrcB C-terminal domain TO73_1776 0140447896491563e021b648a2d38c6d 474 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 4 472 54.63 T 11-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 TO73_1776 0140447896491563e021b648a2d38c6d 474 Gene3D G3DSA:3.90.1150.10 332 457 3.1E-47 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1776 0140447896491563e021b648a2d38c6d 474 SUPERFAMILY SSF53383 3 470 2.7E-121 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1776 0140447896491563e021b648a2d38c6d 474 Pfam PF02347 Glycine cleavage system P-protein 88 363 4.7E-5 T 11-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TO73_1776 0140447896491563e021b648a2d38c6d 474 Gene3D G3DSA:3.40.640.10 83 319 1.9E-56 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 SUPERFAMILY SSF53223 4 119 4.22E-33 T 11-10-2018 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 4 278 37.414 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 Gene3D G3DSA:3.40.50.720 7 254 2.4E-106 T 11-10-2018 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 255 263 - T 11-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 72 99 3.2E-74 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 251 269 3.2E-74 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 31 53 3.2E-74 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 152 172 3.2E-74 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 201 230 3.2E-74 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 107 128 3.2E-74 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 SUPERFAMILY SSF51735 120 274 2.11E-47 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 118 1.7E-32 T 11-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 121 274 3.9E-67 T 11-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TO73_0753 d5fb2f80fc5f9ccd38afdf9ba14da57f 283 Gene3D G3DSA:3.40.50.10860 9 272 2.4E-106 T 11-10-2018 TO73_1002 b183dea8f1cdb2ffb4232f40b19420f1 481 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 271 469 1.6E-71 T 11-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal TO73_1002 b183dea8f1cdb2ffb4232f40b19420f1 481 PIRSF PIRSF000331 1 479 1.4E-187 T 11-10-2018 IPR004925 HpaB/PvcC/4-BUDH TO73_1002 b183dea8f1cdb2ffb4232f40b19420f1 481 Gene3D G3DSA:1.10.3140.10 1 138 4.4E-60 T 11-10-2018 TO73_1002 b183dea8f1cdb2ffb4232f40b19420f1 481 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 264 1.1E-98 T 11-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal TO73_1002 b183dea8f1cdb2ffb4232f40b19420f1 481 TIGRFAM TIGR02309 HpaB-1: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 2 471 2.0E-262 T 11-10-2018 IPR012687 4-HPA 3-monooxygenase large component, Deinococcus-type GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 TO73_1002 b183dea8f1cdb2ffb4232f40b19420f1 481 SUPERFAMILY SSF56645 1 264 5.5E-81 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_1002 b183dea8f1cdb2ffb4232f40b19420f1 481 Gene3D G3DSA:2.40.110.10 139 266 2.0E-49 T 11-10-2018 TO73_1002 b183dea8f1cdb2ffb4232f40b19420f1 481 Gene3D G3DSA:1.20.140.10 267 481 1.3E-95 T 11-10-2018 TO73_1002 b183dea8f1cdb2ffb4232f40b19420f1 481 SUPERFAMILY SSF47203 255 470 1.2E-66 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 SUPERFAMILY SSF69742 4 145 8.5E-41 T 11-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 6 341 4.7E-101 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 Gene3D G3DSA:3.40.50.720 148 295 4.8E-42 T 11-10-2018 TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 SUPERFAMILY SSF51735 148 297 1.48E-34 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 PIRSF PIRSF000445 3 349 1.0E-118 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 376 26.082 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 86 109 - T 11-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 159 288 2.9E-35 T 11-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 Gene3D G3DSA:3.30.460.30 4 147 4.7E-44 T 11-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TO73_0455 deebc28da16f9509dfc8b59cd1cf5096 392 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 8 143 3.2E-40 T 11-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TO73_0958 8aa53db2c198aaabf89cdead4d50c904 258 SUPERFAMILY SSF52540 2 237 1.25E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0958 8aa53db2c198aaabf89cdead4d50c904 258 Pfam PF00005 ABC transporter 18 167 2.8E-23 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0958 8aa53db2c198aaabf89cdead4d50c904 258 SMART SM00382 27 217 1.1E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0958 8aa53db2c198aaabf89cdead4d50c904 258 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0958 8aa53db2c198aaabf89cdead4d50c904 258 Gene3D G3DSA:3.40.50.300 1 255 9.2E-52 T 11-10-2018 TO73_1862 f7fa556e9b02a3196478e521b6cdd3a2 339 Pfam PF00005 ABC transporter 27 190 2.9E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1862 f7fa556e9b02a3196478e521b6cdd3a2 339 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1862 f7fa556e9b02a3196478e521b6cdd3a2 339 SUPERFAMILY SSF52540 6 261 1.54E-69 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1862 f7fa556e9b02a3196478e521b6cdd3a2 339 Gene3D G3DSA:3.40.50.300 4 339 1.9E-98 T 11-10-2018 TO73_1862 f7fa556e9b02a3196478e521b6cdd3a2 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 329 2.2E-22 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TO73_1862 f7fa556e9b02a3196478e521b6cdd3a2 339 SMART SM00382 35 240 1.3E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1862 f7fa556e9b02a3196478e521b6cdd3a2 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 308 2.3E-16 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 SUPERFAMILY SSF52540 99 303 1.2E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0646 e9180948dcbd745cc9218172817f00f9 304 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 26 303 59.419 T 11-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 SMART SM00962 102 303 1.1E-112 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 276 289 - T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 SMART SM00963 7 76 1.2E-9 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 29 302 5.2E-100 T 11-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 Pfam PF00448 SRP54-type protein, GTPase domain 104 302 1.8E-75 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 Pfam PF02881 SRP54-type protein, helical bundle domain 27 70 9.1E-8 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 SMART SM00382 101 281 3.0E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0646 e9180948dcbd745cc9218172817f00f9 304 Gene3D G3DSA:3.40.50.300 97 304 6.9E-79 T 11-10-2018 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 Gene3D G3DSA:1.20.120.140 22 96 1.1E-45 T 11-10-2018 TO73_0646 e9180948dcbd745cc9218172817f00f9 304 SUPERFAMILY SSF47364 22 78 7.2E-17 T 11-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TO73_1527 a95938bd7e72fb822a23f9d156a038c8 620 SMART SM00790 5 207 4.8E-107 T 11-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_1527 a95938bd7e72fb822a23f9d156a038c8 620 SUPERFAMILY SSF48310 215 619 3.53E-100 T 11-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_1527 a95938bd7e72fb822a23f9d156a038c8 620 Gene3D G3DSA:1.10.569.10 241 430 3.0E-107 T 11-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TO73_1527 a95938bd7e72fb822a23f9d156a038c8 620 Gene3D G3DSA:3.60.9.10 3 210 1.3E-73 T 11-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TO73_1527 a95938bd7e72fb822a23f9d156a038c8 620 SUPERFAMILY SSF56228 4 209 1.31E-66 T 11-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TO73_1527 a95938bd7e72fb822a23f9d156a038c8 620 Gene3D G3DSA:1.10.599.10 240 612 3.0E-107 T 11-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TO73_1527 a95938bd7e72fb822a23f9d156a038c8 620 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 204 9.0E-68 T 11-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_1527 a95938bd7e72fb822a23f9d156a038c8 620 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 221 612 2.2E-102 T 11-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_2239 350c005e8d809954749440bbfae3ee4a 529 Gene3D G3DSA:3.40.449.10 24 212 3.2E-231 T 11-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TO73_2239 350c005e8d809954749440bbfae3ee4a 529 PIRSF PIRSF006294 1 528 3.0E-237 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 TO73_2239 350c005e8d809954749440bbfae3ee4a 529 Gene3D G3DSA:3.90.228.20 213 513 3.2E-231 T 11-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TO73_2239 350c005e8d809954749440bbfae3ee4a 529 Gene3D G3DSA:2.170.8.10 34 330 3.2E-231 T 11-10-2018 TO73_2239 350c005e8d809954749440bbfae3ee4a 529 Pfam PF01293 Phosphoenolpyruvate carboxykinase 14 481 3.8E-215 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 TO73_2239 350c005e8d809954749440bbfae3ee4a 529 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 8 528 55.161 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 TO73_2239 350c005e8d809954749440bbfae3ee4a 529 SUPERFAMILY SSF68923 3 211 2.96E-83 T 11-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TO73_2239 350c005e8d809954749440bbfae3ee4a 529 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 2 527 3.0E-216 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 TO73_2239 350c005e8d809954749440bbfae3ee4a 529 SUPERFAMILY SSF53795 212 527 8.24E-135 T 11-10-2018 TO73_1517 c20ff88df2594f63931f0bb14ff4a090 202 SUPERFAMILY SSF52540 1 199 9.55E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1517 c20ff88df2594f63931f0bb14ff4a090 202 Pfam PF01712 Deoxynucleoside kinase 3 197 1.0E-53 T 11-10-2018 IPR031314 Deoxynucleoside kinase domain TO73_1517 c20ff88df2594f63931f0bb14ff4a090 202 PIRSF PIRSF000705 1 200 9.1E-60 T 11-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 TO73_1517 c20ff88df2594f63931f0bb14ff4a090 202 Gene3D G3DSA:3.40.50.300 1 200 1.2E-57 T 11-10-2018 TO73_2370 b29fba9927564df2fc2077adbb51a5df 272 Pfam PF03668 P-loop ATPase protein family 1 272 2.4E-75 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 TO73_2370 b29fba9927564df2fc2077adbb51a5df 272 PIRSF PIRSF005052 1 272 2.3E-92 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 TO73_2370 b29fba9927564df2fc2077adbb51a5df 272 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 271 35.477 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 TO73_2370 b29fba9927564df2fc2077adbb51a5df 272 Gene3D G3DSA:3.40.50.300 2 151 1.9E-6 T 11-10-2018 TO73_2370 b29fba9927564df2fc2077adbb51a5df 272 SUPERFAMILY SSF52540 3 146 6.12E-13 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1880 89fdef9482d0523599408ce98b6333ed 164 Gene3D G3DSA:3.40.50.880 2 163 1.2E-13 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1880 89fdef9482d0523599408ce98b6333ed 164 SUPERFAMILY SSF52317 4 144 4.84E-12 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0889 0bd45ecc157ca8098acebb2eb7fa8ccb 259 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 257 2.7E-93 T 11-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TO73_0889 0bd45ecc157ca8098acebb2eb7fa8ccb 259 Gene3D G3DSA:3.40.1190.20 1 259 3.5E-101 T 11-10-2018 IPR029056 Ribokinase-like TO73_0889 0bd45ecc157ca8098acebb2eb7fa8ccb 259 SUPERFAMILY SSF53613 2 258 6.86E-83 T 11-10-2018 IPR029056 Ribokinase-like TO73_0889 0bd45ecc157ca8098acebb2eb7fa8ccb 259 Pfam PF08543 Phosphomethylpyrimidine kinase 12 256 6.3E-90 T 11-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 TO73_2260 ed19af3e4c3f5c21ecf617be9074ea54 105 SUPERFAMILY SSF55826 8 98 1.57E-18 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TO73_2260 ed19af3e4c3f5c21ecf617be9074ea54 105 Pfam PF04073 Aminoacyl-tRNA editing domain 29 98 1.1E-12 T 11-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TO73_2260 ed19af3e4c3f5c21ecf617be9074ea54 105 Gene3D G3DSA:3.90.960.10 1 100 7.3E-24 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TO73_2100 181eb7284e20421f3e2e9148ae24303f 203 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 192 46.408 T 11-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 TO73_2100 181eb7284e20421f3e2e9148ae24303f 203 Gene3D G3DSA:3.90.950.10 1 192 2.3E-71 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TO73_2100 181eb7284e20421f3e2e9148ae24303f 203 Pfam PF01725 Ham1 family 3 188 8.3E-56 T 11-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TO73_2100 181eb7284e20421f3e2e9148ae24303f 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 190 1.3E-55 T 11-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TO73_2100 181eb7284e20421f3e2e9148ae24303f 203 SUPERFAMILY SSF52972 1 190 8.37E-66 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TO73_1163 56e0268e2d3cdd799d792551d3e5bf75 192 SUPERFAMILY SSF57716 144 190 1.13E-15 T 11-10-2018 TO73_1163 56e0268e2d3cdd799d792551d3e5bf75 192 SUPERFAMILY SSF52540 9 142 2.44E-39 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1163 56e0268e2d3cdd799d792551d3e5bf75 192 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 175 188 - T 11-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TO73_1163 56e0268e2d3cdd799d792551d3e5bf75 192 Pfam PF00265 Thymidine kinase 9 188 1.5E-50 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TO73_1163 56e0268e2d3cdd799d792551d3e5bf75 192 Hamap MF_00124 Thymidine kinase [tdk]. 8 191 35.789 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TO73_1163 56e0268e2d3cdd799d792551d3e5bf75 192 PIRSF PIRSF035805 6 191 6.2E-60 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TO73_1163 56e0268e2d3cdd799d792551d3e5bf75 192 Gene3D G3DSA:3.40.50.300 3 142 3.2E-54 T 11-10-2018 TO73_1163 56e0268e2d3cdd799d792551d3e5bf75 192 Gene3D G3DSA:3.30.60.20 143 192 8.3E-24 T 11-10-2018 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 393 441 1.3E-10 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 Gene3D G3DSA:3.30.310.50 359 443 2.4E-24 T 11-10-2018 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 SUPERFAMILY SSF53738 229 359 3.92E-29 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 SUPERFAMILY SSF53738 137 243 2.9E-20 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 221 236 4.5E-8 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 192 205 4.5E-8 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 81 95 4.5E-8 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 SUPERFAMILY SSF53738 3 150 6.28E-36 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 SUPERFAMILY SSF55957 385 445 6.8E-18 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 245 351 2.4E-24 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 119 9.3E-33 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 Gene3D G3DSA:3.40.120.10 242 358 7.4E-43 T 11-10-2018 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 Gene3D G3DSA:3.40.120.10 157 241 6.1E-20 T 11-10-2018 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 82 91 - T 11-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 138 238 2.6E-16 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TO73_0898 e44d7bf956ac01688d5bfef5a9cdd8cc 446 Gene3D G3DSA:3.40.120.10 1 133 3.3E-42 T 11-10-2018 TO73_2176 f58ad5903d49fe8e469e118c4ab61f2c 402 SUPERFAMILY SSF103473 10 400 2.09E-46 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_2176 f58ad5903d49fe8e469e118c4ab61f2c 402 Gene3D G3DSA:1.20.1250.20 202 402 2.7E-20 T 11-10-2018 TO73_2176 f58ad5903d49fe8e469e118c4ab61f2c 402 ProSitePatterns PS00216 Sugar transport proteins signature 1. 272 289 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TO73_2176 f58ad5903d49fe8e469e118c4ab61f2c 402 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 82 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TO73_2176 f58ad5903d49fe8e469e118c4ab61f2c 402 Pfam PF13347 MFS/sugar transport protein 44 337 8.8E-21 T 11-10-2018 TO73_2176 f58ad5903d49fe8e469e118c4ab61f2c 402 Gene3D G3DSA:1.20.1250.20 7 190 3.7E-20 T 11-10-2018 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 SUPERFAMILY SSF53187 138 448 1.66E-109 T 11-10-2018 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 SUPERFAMILY SSF52949 16 121 2.83E-15 T 11-10-2018 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 143 444 7.5E-119 T 11-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 14 114 4.3E-10 T 11-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 PRINTS PR00481 Cytosol aminopeptidase signature 239 260 1.6E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 PRINTS PR00481 Cytosol aminopeptidase signature 298 318 1.6E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 PRINTS PR00481 Cytosol aminopeptidase signature 217 234 1.6E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 PRINTS PR00481 Cytosol aminopeptidase signature 276 297 1.6E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 PRINTS PR00481 Cytosol aminopeptidase signature 326 341 1.6E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 Gene3D G3DSA:3.40.220.10 5 127 4.9E-14 T 11-10-2018 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 302 309 - T 11-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 Gene3D G3DSA:3.40.630.10 128 451 3.8E-130 T 11-10-2018 TO73_2206 eb1f491c75f5976ab6afe8691ff29b7d 451 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 1 451 31.766 T 11-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 TO73_0281 6bea375e72e09ac00d2328294ca4b6a0 138 Gene3D G3DSA:3.90.1010.10 1 138 7.2E-59 T 11-10-2018 TO73_0281 6bea375e72e09ac00d2328294ca4b6a0 138 Pfam PF01592 NifU-like N terminal domain 8 124 4.0E-24 T 11-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 TO73_0281 6bea375e72e09ac00d2328294ca4b6a0 138 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 4 138 3.2E-51 T 11-10-2018 TO73_0281 6bea375e72e09ac00d2328294ca4b6a0 138 SUPERFAMILY SSF82649 3 138 1.7E-49 T 11-10-2018 TO73_0551 66a00c259263096393a5daf8cd2083a3 349 Gene3D G3DSA:1.20.1090.10 162 338 1.2E-51 T 11-10-2018 TO73_0551 66a00c259263096393a5daf8cd2083a3 349 SUPERFAMILY SSF56796 1 339 1.96E-84 T 11-10-2018 TO73_0551 66a00c259263096393a5daf8cd2083a3 349 Pfam PF01761 3-dehydroquinate synthase 58 304 7.0E-71 T 11-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TO73_0551 66a00c259263096393a5daf8cd2083a3 349 Gene3D G3DSA:3.40.50.1970 1 161 8.5E-54 T 11-10-2018 TO73_0551 66a00c259263096393a5daf8cd2083a3 349 PIRSF PIRSF001455 8 343 1.4E-91 T 11-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TO73_0153 765ca25d7dcda2dec42998416d08378b 261 SUPERFAMILY SSF52096 6 261 1.87E-82 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_0153 765ca25d7dcda2dec42998416d08378b 261 Gene3D G3DSA:1.10.12.10 204 261 2.1E-25 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TO73_0153 765ca25d7dcda2dec42998416d08378b 261 Gene3D G3DSA:3.90.226.10 8 203 2.0E-74 T 11-10-2018 TO73_0153 765ca25d7dcda2dec42998416d08378b 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 260 2.6E-63 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 Pfam PF03466 LysR substrate binding domain 88 291 1.5E-40 T 11-10-2018 IPR005119 LysR, substrate-binding TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 Gene3D G3DSA:1.10.10.10 1 83 5.6E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 SUPERFAMILY SSF53850 89 296 1.36E-38 T 11-10-2018 TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.0E-20 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 Gene3D G3DSA:3.40.190.10 161 261 2.6E-62 T 11-10-2018 TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.6E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.6E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.6E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 SUPERFAMILY SSF46785 1 111 1.76E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1996 c16cf8d0538349d8e57e9a7bd2f5b874 302 Gene3D G3DSA:3.40.190.10 91 287 2.6E-62 T 11-10-2018 TO73_0649 d18cfbd0a845e6673891d81e9bffa904 242 Gene3D G3DSA:3.40.50.300 3 242 1.0E-68 T 11-10-2018 TO73_0649 d18cfbd0a845e6673891d81e9bffa904 242 SUPERFAMILY SSF52540 5 239 8.99E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0649 d18cfbd0a845e6673891d81e9bffa904 242 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 5 242 1.5E-98 T 11-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 TO73_0649 d18cfbd0a845e6673891d81e9bffa904 242 SMART SM00382 29 215 1.1E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0649 d18cfbd0a845e6673891d81e9bffa904 242 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0649 d18cfbd0a845e6673891d81e9bffa904 242 Pfam PF00005 ABC transporter 21 165 7.2E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1653 0d429ed7355a5e8803d58a375bc85d34 221 ProSitePatterns PS00958 Transaldolase active site. 87 104 - T 11-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TO73_1653 0d429ed7355a5e8803d58a375bc85d34 221 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 219 2.3E-83 T 11-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TO73_1653 0d429ed7355a5e8803d58a375bc85d34 221 Hamap MF_00494 Probable transaldolase [tal]. 1 221 43.846 T 11-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TO73_1653 0d429ed7355a5e8803d58a375bc85d34 221 SUPERFAMILY SSF51569 1 219 4.92E-73 T 11-10-2018 TO73_1653 0d429ed7355a5e8803d58a375bc85d34 221 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 11-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TO73_1653 0d429ed7355a5e8803d58a375bc85d34 221 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 206 3.5E-57 T 11-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TO73_1653 0d429ed7355a5e8803d58a375bc85d34 221 Gene3D G3DSA:3.20.20.70 1 221 4.1E-92 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0139 be8070d21e442a15336b919906fb7744 324 SMART SM00861 4 179 1.4E-76 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_0139 be8070d21e442a15336b919906fb7744 324 SUPERFAMILY SSF52518 4 192 9.64E-75 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_0139 be8070d21e442a15336b919906fb7744 324 Gene3D G3DSA:3.40.50.970 1 192 6.4E-97 T 11-10-2018 TO73_0139 be8070d21e442a15336b919906fb7744 324 Gene3D G3DSA:3.40.50.920 193 324 1.4E-44 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_0139 be8070d21e442a15336b919906fb7744 324 SUPERFAMILY SSF52922 188 323 4.97E-39 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_0139 be8070d21e442a15336b919906fb7744 324 Pfam PF02780 Transketolase, C-terminal domain 194 311 1.7E-33 T 11-10-2018 IPR033248 Transketolase, C-terminal domain TO73_0139 be8070d21e442a15336b919906fb7744 324 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 2.0E-52 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_0190 f5405320855fa1f9b162f877872652c7 82 Pfam PF14520 Helix-hairpin-helix domain 39 80 4.4E-7 T 11-10-2018 TO73_0190 f5405320855fa1f9b162f877872652c7 82 Gene3D G3DSA:1.10.150.20 35 79 2.1E-8 T 11-10-2018 TO73_0190 f5405320855fa1f9b162f877872652c7 82 SUPERFAMILY SSF47794 39 79 3.92E-7 T 11-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 TO73_2735 71545a201eeedebd861d637a230f81fb 127 SUPERFAMILY SSF53098 4 126 4.93E-5 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2188 7478cd0398a770db4bd6e62f6097711b 202 Gene3D G3DSA:3.40.630.30 1 201 4.8E-50 T 11-10-2018 TO73_2188 7478cd0398a770db4bd6e62f6097711b 202 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 1.9E-16 T 11-10-2018 IPR000182 GNAT domain TO73_2188 7478cd0398a770db4bd6e62f6097711b 202 SUPERFAMILY SSF55729 3 180 1.67E-29 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 SMART SM00116 204 252 1.4E-11 T 11-10-2018 IPR000644 CBS domain TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 SMART SM00116 140 193 0.0024 T 11-10-2018 IPR000644 CBS domain TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 TIGRFAM TIGR00400 mgtE: magnesium transporter 8 447 4.6E-123 T 11-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 Gene3D G3DSA:1.10.357.20 270 446 1.3E-61 T 11-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 Gene3D G3DSA:3.10.580.10 129 251 1.4E-52 T 11-10-2018 TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 SUPERFAMILY SSF54631 133 265 8.84E-40 T 11-10-2018 TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 Gene3D G3DSA:1.25.60.10 1 128 1.3E-37 T 11-10-2018 IPR038076 MgtE, N-terminal domain superfamily TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 Pfam PF00571 CBS domain 134 191 2.8E-10 T 11-10-2018 IPR000644 CBS domain TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 Pfam PF00571 CBS domain 197 252 2.7E-14 T 11-10-2018 IPR000644 CBS domain TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 SUPERFAMILY SSF161093 276 446 7.59E-49 T 11-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 SMART SM00924 27 133 5.1E-25 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 SUPERFAMILY SSF158791 8 130 1.83E-26 T 11-10-2018 TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 Pfam PF03448 MgtE intracellular N domain 28 131 2.6E-23 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TO73_1122 4fa0b40beac35499306164d4dfa30e20 448 Pfam PF01769 Divalent cation transporter 319 439 3.4E-28 T 11-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TO73_0255 588690e25bd8394c3eada8e2f1af282a 172 Pfam PF11821 Protein of unknown function (DUF3341) 3 166 3.2E-51 T 11-10-2018 IPR021776 Protein of unknown function DUF3341 TO73_0228 d44fb74f267eac5f9cafab73e4276336 120 Pfam PF04519 Polymer-forming cytoskeletal 10 106 1.2E-22 T 11-10-2018 IPR007607 Bactofilin A/B TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Gene3D G3DSA:3.50.30.10 378 502 2.3E-63 T 11-10-2018 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 PIRSF PIRSF000853 1 859 0.0 T 11-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 299 351 1.4E-9 T 11-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 57 284 7.7E-29 T 11-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Gene3D G3DSA:3.30.470.20 239 336 8.9E-40 T 11-10-2018 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 1 853 0.0 T 11-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 745 763 - T 11-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Gene3D G3DSA:3.20.20.60 525 853 2.8E-132 T 11-10-2018 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 510 852 4.5E-83 T 11-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 443 454 - T 11-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 SUPERFAMILY SSF56059 1 374 1.08E-125 T 11-10-2018 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Gene3D G3DSA:3.30.1490.20 11 238 2.8E-88 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 SUPERFAMILY SSF51621 512 857 1.31E-109 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Pfam PF00391 PEP-utilising enzyme, mobile domain 417 496 1.0E-25 T 11-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Gene3D G3DSA:1.10.189.10 340 522 2.3E-63 T 11-10-2018 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 Gene3D G3DSA:1.20.80.30 107 193 2.8E-88 T 11-10-2018 TO73_2403 19d2b12dfe4d48178d953eb8e95c6932 860 SUPERFAMILY SSF52009 380 505 1.44E-35 T 11-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TO73_1598 b99c52eb97ee843b4fa4a5feed80cf01 99 SUPERFAMILY SSF81333 31 96 5.62E-13 T 11-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TO73_1598 b99c52eb97ee843b4fa4a5feed80cf01 99 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 47 73 1.7E-7 T 11-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1598 b99c52eb97ee843b4fa4a5feed80cf01 99 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 74 97 1.7E-7 T 11-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1598 b99c52eb97ee843b4fa4a5feed80cf01 99 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 1 16 1.7E-7 T 11-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1598 b99c52eb97ee843b4fa4a5feed80cf01 99 Gene3D G3DSA:1.20.120.610 4 97 7.0E-16 T 11-10-2018 TO73_1598 b99c52eb97ee843b4fa4a5feed80cf01 99 Pfam PF00137 ATP synthase subunit C 37 95 4.1E-15 T 11-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TO73_0972 b58f8e4179592505be6562f25345732e 158 PRINTS PR00601 Bacterioferritin signature 44 64 1.3E-43 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 PRINTS PR00601 Bacterioferritin signature 107 127 1.3E-43 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 PRINTS PR00601 Bacterioferritin signature 3 22 1.3E-43 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 PRINTS PR00601 Bacterioferritin signature 128 149 1.3E-43 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 PRINTS PR00601 Bacterioferritin signature 65 85 1.3E-43 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 PRINTS PR00601 Bacterioferritin signature 23 43 1.3E-43 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 PRINTS PR00601 Bacterioferritin signature 86 106 1.3E-43 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 Gene3D G3DSA:1.20.1260.10 1 154 1.2E-57 T 11-10-2018 IPR012347 Ferritin-like TO73_0972 b58f8e4179592505be6562f25345732e 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 152 4.7E-51 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 SUPERFAMILY SSF47240 1 154 1.61E-45 T 11-10-2018 IPR009078 Ferritin-like superfamily TO73_0972 b58f8e4179592505be6562f25345732e 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 Pfam PF00210 Ferritin-like domain 8 144 1.1E-32 T 11-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TO73_0972 b58f8e4179592505be6562f25345732e 158 PIRSF PIRSF002560 1 156 1.0E-57 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TO73_0912 6f3827b211a786e8b01607814aaac29a 287 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 271 3.7E-29 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_1485 3e9b6a04712ec0693e96202bf5b10e9e 464 Gene3D G3DSA:3.30.2290.10 2 225 1.4E-25 T 11-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TO73_1485 3e9b6a04712ec0693e96202bf5b10e9e 464 Pfam PF01523 Putative modulator of DNA gyrase 21 317 3.6E-61 T 11-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TO73_1485 3e9b6a04712ec0693e96202bf5b10e9e 464 SUPERFAMILY SSF111283 3 463 5.49E-114 T 11-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TO73_1485 3e9b6a04712ec0693e96202bf5b10e9e 464 PIRSF PIRSF004919 1 464 7.0E-115 T 11-10-2018 IPR025502 TldD TO73_0099 3fd85b690e85b55913b284219e12d935 344 SMART SM00859 5 140 2.8E-42 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TO73_0099 3fd85b690e85b55913b284219e12d935 344 Gene3D G3DSA:3.30.360.10 146 316 2.9E-112 T 11-10-2018 TO73_0099 3fd85b690e85b55913b284219e12d935 344 SUPERFAMILY SSF51735 5 172 1.69E-35 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0099 3fd85b690e85b55913b284219e12d935 344 Hamap MF_02083 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase [lysY]. 4 344 50.506 T 11-10-2018 IPR037535 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase GO:0016620 TO73_0099 3fd85b690e85b55913b284219e12d935 344 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 4 338 37.77 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_0099 3fd85b690e85b55913b284219e12d935 344 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 143 159 - T 11-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_0099 3fd85b690e85b55913b284219e12d935 344 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 139 9.1E-25 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TO73_0099 3fd85b690e85b55913b284219e12d935 344 SUPERFAMILY SSF55347 148 312 4.97E-38 T 11-10-2018 TO73_0099 3fd85b690e85b55913b284219e12d935 344 Gene3D G3DSA:3.40.50.720 7 330 2.9E-112 T 11-10-2018 TO73_0099 3fd85b690e85b55913b284219e12d935 344 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 315 1.4E-8 T 11-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_0099 3fd85b690e85b55913b284219e12d935 344 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 6 344 2.4E-109 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 Gene3D G3DSA:3.40.50.300 157 282 6.3E-27 T 11-10-2018 TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 Pfam PF13361 UvrD-like helicase C-terminal domain 490 599 9.5E-17 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 Pfam PF12705 PD-(D/E)XK nuclease superfamily 693 837 1.3E-7 T 11-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 Gene3D G3DSA:3.40.50.300 2 126 3.3E-21 T 11-10-2018 TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 Pfam PF13245 AAA domain 5 243 7.2E-23 T 11-10-2018 TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 SUPERFAMILY SSF52540 5 602 1.75E-92 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 Pfam PF13361 UvrD-like helicase C-terminal domain 314 388 5.2E-7 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 Gene3D G3DSA:3.40.50.300 315 415 3.3E-18 T 11-10-2018 TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 SUPERFAMILY SSF52980 695 838 2.25E-9 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 Gene3D G3DSA:3.40.50.300 458 613 1.0E-22 T 11-10-2018 TO73_0503 7f643370bf6da6de6941635d06cd71ef 868 Gene3D G3DSA:3.90.320.10 776 840 1.0E-7 T 11-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TO73_1595 3b69976f033a4a5f316b9c2d0a59e5a9 106 Gene3D G3DSA:3.40.50.10580 3 102 7.1E-19 T 11-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1595 3b69976f033a4a5f316b9c2d0a59e5a9 106 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 105 18.403 T 11-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal TO73_1595 3b69976f033a4a5f316b9c2d0a59e5a9 106 SUPERFAMILY SSF159468 3 105 4.84E-21 T 11-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1595 3b69976f033a4a5f316b9c2d0a59e5a9 106 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 83 1.8E-12 T 11-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 10 30 5.1E-6 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 77 95 5.1E-6 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 Pfam PF07650 KH domain 208 285 3.7E-19 T 11-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 Pfam PF01926 50S ribosome-binding GTPase 10 126 7.7E-22 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 Gene3D G3DSA:3.40.50.300 1 184 4.6E-52 T 11-10-2018 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 Gene3D G3DSA:3.30.300.20 185 301 8.4E-42 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 8 279 3.9E-70 T 11-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 SUPERFAMILY SSF54814 184 297 1.74E-37 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 Hamap MF_00367 GTPase Era [era]. 5 296 33.127 T 11-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 138 1.0E-23 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_1999 30edc6cc4c2f466a874cb1716bf32a22 301 SUPERFAMILY SSF52540 10 206 6.21E-38 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 11 600 9.0E-282 T 11-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 PRINTS PR00301 70kDa heat shock protein signature 336 352 1.1E-74 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 PRINTS PR00301 70kDa heat shock protein signature 367 387 1.1E-74 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 PRINTS PR00301 70kDa heat shock protein signature 390 409 1.1E-74 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 PRINTS PR00301 70kDa heat shock protein signature 202 212 1.1E-74 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 PRINTS PR00301 70kDa heat shock protein signature 61 69 1.1E-74 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 PRINTS PR00301 70kDa heat shock protein signature 39 51 1.1E-74 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 PRINTS PR00301 70kDa heat shock protein signature 471 487 1.1E-74 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 PRINTS PR00301 70kDa heat shock protein signature 143 163 1.1E-74 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 PRINTS PR00301 70kDa heat shock protein signature 11 24 1.1E-74 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 Gene3D G3DSA:3.30.420.40 185 368 3.7E-155 T 11-10-2018 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 SUPERFAMILY SSF100920 386 542 1.31E-61 T 11-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 SUPERFAMILY SSF53067 10 188 2.91E-63 T 11-10-2018 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 Gene3D G3DSA:2.60.34.10 379 561 1.3E-77 T 11-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 SUPERFAMILY SSF53067 191 384 3.58E-66 T 11-10-2018 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 Gene3D G3DSA:3.30.420.40 13 378 3.7E-155 T 11-10-2018 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 196 209 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 Pfam PF00012 Hsp70 protein 12 600 2.5E-245 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 15 22 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 Gene3D G3DSA:3.90.640.10 229 318 3.7E-155 T 11-10-2018 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 339 353 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TO73_1923 60e6b913ceecce27d7788d83d91eb553 624 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 9 623 36.833 T 11-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TO73_2087 c4e239c2ccdcc23e7ad85b5cb56a42ff 396 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 209 395 1.4E-28 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_2087 c4e239c2ccdcc23e7ad85b5cb56a42ff 396 SUPERFAMILY SSF161098 206 379 1.11E-16 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2087 c4e239c2ccdcc23e7ad85b5cb56a42ff 396 Gene3D G3DSA:1.10.3720.10 186 391 2.6E-15 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2087 c4e239c2ccdcc23e7ad85b5cb56a42ff 396 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 13 61 1.2E-18 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TO73_1347 d743f324136361abc8d39172cdb98ed8 204 SUPERFAMILY SSF54719 92 202 4.58E-44 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 99 199 4.1E-39 T 11-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 167 174 - T 11-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 Gene3D G3DSA:2.40.500.20 93 204 4.5E-48 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 SUPERFAMILY SSF46609 3 93 1.44E-34 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 PRINTS PR01703 Manganese superoxide dismutase signature 8 19 3.5E-26 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 PRINTS PR01703 Manganese superoxide dismutase signature 165 177 3.5E-26 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 PRINTS PR01703 Manganese superoxide dismutase signature 29 42 3.5E-26 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 PRINTS PR01703 Manganese superoxide dismutase signature 128 136 3.5E-26 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 PRINTS PR01703 Manganese superoxide dismutase signature 75 88 3.5E-26 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 5 91 7.5E-31 T 11-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 PIRSF PIRSF000349 1 204 1.8E-78 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_1347 d743f324136361abc8d39172cdb98ed8 204 Gene3D G3DSA:1.10.287.990 22 92 3.6E-32 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TO73_2608 38206ae62d7c4b7d77c68e5787d8babe 381 Pfam PF05175 Methyltransferase small domain 142 225 7.9E-7 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TO73_2608 38206ae62d7c4b7d77c68e5787d8babe 381 Gene3D G3DSA:3.40.50.150 139 292 6.9E-20 T 11-10-2018 TO73_2608 38206ae62d7c4b7d77c68e5787d8babe 381 SUPERFAMILY SSF53335 115 302 4.72E-23 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1370 0b658e5c5064fab94017c6b1dd8ad8f1 290 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 9.2E-65 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TO73_1370 0b658e5c5064fab94017c6b1dd8ad8f1 290 SUPERFAMILY SSF48179 185 287 7.31E-34 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TO73_1370 0b658e5c5064fab94017c6b1dd8ad8f1 290 Gene3D G3DSA:3.40.50.720 1 188 9.9E-69 T 11-10-2018 TO73_1370 0b658e5c5064fab94017c6b1dd8ad8f1 290 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 4.6E-35 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TO73_1370 0b658e5c5064fab94017c6b1dd8ad8f1 290 SUPERFAMILY SSF51735 1 185 1.14E-61 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1370 0b658e5c5064fab94017c6b1dd8ad8f1 290 Gene3D G3DSA:1.10.1040.10 193 278 8.8E-36 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TO73_1370 0b658e5c5064fab94017c6b1dd8ad8f1 290 PIRSF PIRSF000105 1 290 7.9E-91 T 11-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 SUPERFAMILY SSF56053 1 82 3.27E-25 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 Gene3D G3DSA:3.90.930.12 83 180 2.3E-35 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 PIRSF PIRSF002162 1 177 8.0E-45 T 11-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.188 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 SUPERFAMILY SSF56053 83 176 2.75E-31 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 175 8.8E-68 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 PRINTS PR00059 Ribosomal protein L6 signature 71 96 2.4E-26 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 PRINTS PR00059 Ribosomal protein L6 signature 141 162 2.4E-26 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 PRINTS PR00059 Ribosomal protein L6 signature 99 115 2.4E-26 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 Gene3D G3DSA:3.90.930.12 1 82 1.0E-32 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 Pfam PF00347 Ribosomal protein L6 91 164 2.8E-15 T 11-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0391 f8d1ca744463d89883f3236c52fa976b 180 Pfam PF00347 Ribosomal protein L6 11 82 7.1E-21 T 11-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_2179 518aa50405523c67288ea44a5effbe92 359 Gene3D G3DSA:3.40.190.170 32 336 2.6E-131 T 11-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TO73_2179 518aa50405523c67288ea44a5effbe92 359 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 25 4.9E-4 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TO73_2179 518aa50405523c67288ea44a5effbe92 359 PIRSF PIRSF039026 1 355 2.6E-133 T 11-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TO73_2179 518aa50405523c67288ea44a5effbe92 359 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 321 5.1E-65 T 11-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TO73_2179 518aa50405523c67288ea44a5effbe92 359 Gene3D G3DSA:3.40.190.10 152 322 2.6E-131 T 11-10-2018 TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 SUPERFAMILY SSF55874 161 294 7.2E-22 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 SMART SM00387 194 296 4.1E-15 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 195 285 3.1E-9 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 Gene3D G3DSA:3.30.565.10 158 296 4.0E-21 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 Gene3D G3DSA:1.10.287.130 90 154 1.8E-7 T 11-10-2018 TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 SUPERFAMILY SSF47384 86 151 1.53E-8 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 Pfam PF00512 His Kinase A (phospho-acceptor) domain 104 151 4.6E-7 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 PRINTS PR00344 Bacterial sensor protein C-terminal signature 229 243 3.2E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 PRINTS PR00344 Bacterial sensor protein C-terminal signature 258 276 3.2E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 294 3.2E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 Gene3D G3DSA:3.30.450.20 2 89 4.1E-5 T 11-10-2018 TO73_1965 aeb716d567ecd951b3b5d100e1fb4f0b 296 SUPERFAMILY SSF55785 17 69 4.76E-5 T 11-10-2018 IPR035965 PAS domain superfamily TO73_1580 5b8108302c3af56925f84a0dbcd5cc7a 181 Gene3D G3DSA:3.40.30.10 75 181 1.1E-35 T 11-10-2018 TO73_1580 5b8108302c3af56925f84a0dbcd5cc7a 181 Gene3D G3DSA:1.10.10.1590 1 74 5.3E-29 T 11-10-2018 TO73_1580 5b8108302c3af56925f84a0dbcd5cc7a 181 SUPERFAMILY SSF52833 6 170 4.62E-52 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1580 5b8108302c3af56925f84a0dbcd5cc7a 181 PIRSF PIRSF000216 1 180 1.3E-65 T 11-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1580 5b8108302c3af56925f84a0dbcd5cc7a 181 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 11 157 1.3E-54 T 11-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1580 5b8108302c3af56925f84a0dbcd5cc7a 181 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 12 157 3.6E-49 T 11-10-2018 TO73_1580 5b8108302c3af56925f84a0dbcd5cc7a 181 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 114 132 - T 11-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 SMART SM00954 247 370 1.6E-66 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 SUPERFAMILY SSF109604 9 197 1.04E-72 T 11-10-2018 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 Pfam PF02824 TGS domain 412 471 1.1E-24 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 SUPERFAMILY SSF81301 186 416 9.81E-61 T 11-10-2018 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 SMART SM00471 44 159 2.4E-11 T 11-10-2018 IPR003607 HD/PDEase domain TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 Pfam PF04607 Region found in RelA / SpoT proteins 247 369 3.6E-35 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 Pfam PF13291 ACT domain 655 723 1.0E-6 T 11-10-2018 IPR002912 ACT domain TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 SUPERFAMILY SSF55021 654 725 9.99E-8 T 11-10-2018 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 Pfam PF13328 HD domain 29 181 4.1E-51 T 11-10-2018 IPR003607 HD/PDEase domain TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 Gene3D G3DSA:3.30.70.260 654 726 9.2E-8 T 11-10-2018 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 SUPERFAMILY SSF81271 399 471 2.4E-23 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 Gene3D G3DSA:3.30.460.10 199 350 1.9E-46 T 11-10-2018 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 Gene3D G3DSA:1.10.3210.10 4 197 7.0E-82 T 11-10-2018 TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 Gene3D G3DSA:3.10.20.30 405 480 5.5E-36 T 11-10-2018 IPR012675 Beta-grasp domain superfamily TO73_0147 bb8d060a8f3282a552179ec95550f5b1 726 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 29 723 1.6E-216 T 11-10-2018 IPR004811 RelA/SpoT family GO:0015969 TO73_1925 755b9e44d2bf11d7fd0aed35614dc418 97 SUPERFAMILY SSF47729 7 96 1.47E-30 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TO73_1925 755b9e44d2bf11d7fd0aed35614dc418 97 PRINTS PR01727 Prokaryotic integration host factor signature 46 61 1.6E-15 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TO73_1925 755b9e44d2bf11d7fd0aed35614dc418 97 PRINTS PR01727 Prokaryotic integration host factor signature 80 94 1.6E-15 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TO73_1925 755b9e44d2bf11d7fd0aed35614dc418 97 PRINTS PR01727 Prokaryotic integration host factor signature 64 77 1.6E-15 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TO73_1925 755b9e44d2bf11d7fd0aed35614dc418 97 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 52 71 - T 11-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TO73_1925 755b9e44d2bf11d7fd0aed35614dc418 97 Pfam PF00216 Bacterial DNA-binding protein 7 96 7.1E-34 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TO73_1925 755b9e44d2bf11d7fd0aed35614dc418 97 SMART SM00411 7 96 7.9E-43 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TO73_1925 755b9e44d2bf11d7fd0aed35614dc418 97 Gene3D G3DSA:4.10.520.10 2 97 3.0E-38 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TO73_0293 44068a7ccf3fdc48dd2e6e46e164f268 250 SUPERFAMILY SSF52540 4 229 2.4E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0293 44068a7ccf3fdc48dd2e6e46e164f268 250 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 242 1.4E-100 T 11-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TO73_0293 44068a7ccf3fdc48dd2e6e46e164f268 250 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0293 44068a7ccf3fdc48dd2e6e46e164f268 250 Pfam PF00005 ABC transporter 19 170 1.4E-21 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0293 44068a7ccf3fdc48dd2e6e46e164f268 250 Gene3D G3DSA:3.40.50.300 1 250 1.6E-64 T 11-10-2018 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 16 193 1.4E-73 T 11-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 Pfam PF01479 S4 domain 84 130 3.0E-23 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 Gene3D G3DSA:3.10.290.10 82 178 1.6E-87 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 SUPERFAMILY SSF55174 2 193 3.53E-70 T 11-10-2018 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 ProSitePatterns PS00632 Ribosomal protein S4 signature. 81 105 - T 11-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 2 82 2.6E-24 T 11-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 SMART SM00363 83 147 2.3E-21 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 SMART SM01390 2 82 1.0E-37 T 11-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 193 33.12 T 11-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TO73_0403 ff431c150aa5013e0d8a4dc359215d86 193 Gene3D G3DSA:1.10.1050.10 1 193 1.6E-87 T 11-10-2018 TO73_0572 e141042b111e5f9037b5114484cf151e 268 Gene3D G3DSA:2.10.109.10 25 127 3.3E-10 T 11-10-2018 TO73_0572 e141042b111e5f9037b5114484cf151e 268 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 11-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 TO73_0572 e141042b111e5f9037b5114484cf151e 268 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 19 244 4.9E-31 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TO73_0572 e141042b111e5f9037b5114484cf151e 268 ProSitePatterns PS00760 Signal peptidases I lysine active site. 102 114 - T 11-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 TO73_0572 e141042b111e5f9037b5114484cf151e 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 100 112 4.9E-12 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TO73_0572 e141042b111e5f9037b5114484cf151e 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 4.9E-12 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TO73_0572 e141042b111e5f9037b5114484cf151e 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 202 221 4.9E-12 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TO73_0572 e141042b111e5f9037b5114484cf151e 268 SUPERFAMILY SSF51306 27 244 1.65E-43 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TO73_0572 e141042b111e5f9037b5114484cf151e 268 Pfam PF00717 Peptidase S24-like 36 114 1.7E-6 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TO73_0572 e141042b111e5f9037b5114484cf151e 268 Gene3D G3DSA:2.10.109.10 167 248 1.5E-13 T 11-10-2018 TO73_2004 821306b0b95ae13f04712a39100e092a 311 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 51 255 4.3E-63 T 11-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 TO73_2004 821306b0b95ae13f04712a39100e092a 311 Gene3D G3DSA:3.40.1750.20 146 212 7.8E-70 T 11-10-2018 TO73_2004 821306b0b95ae13f04712a39100e092a 311 SUPERFAMILY SSF52096 41 241 1.04E-37 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_2004 821306b0b95ae13f04712a39100e092a 311 Gene3D G3DSA:3.90.226.10 51 249 7.8E-70 T 11-10-2018 TO73_2004 821306b0b95ae13f04712a39100e092a 311 Pfam PF01343 Peptidase family S49 106 256 8.5E-46 T 11-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TO73_0032 6657e04d076f0a3b71175e6100826058 742 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 346 435 2.8E-29 T 11-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TO73_0032 6657e04d076f0a3b71175e6100826058 742 SUPERFAMILY SSF52210 470 598 1.31E-11 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_0032 6657e04d076f0a3b71175e6100826058 742 SUPERFAMILY SSF55729 25 166 4.63E-21 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_0032 6657e04d076f0a3b71175e6100826058 742 Pfam PF13302 Acetyltransferase (GNAT) domain 27 161 2.1E-8 T 11-10-2018 IPR000182 GNAT domain TO73_0032 6657e04d076f0a3b71175e6100826058 742 SUPERFAMILY SSF52210 326 464 7.85E-30 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_0032 6657e04d076f0a3b71175e6100826058 742 Pfam PF13380 CoA binding domain 208 330 1.3E-16 T 11-10-2018 IPR003781 CoA-binding GO:0048037 TO73_0032 6657e04d076f0a3b71175e6100826058 742 Gene3D G3DSA:3.40.50.261 325 467 4.5E-36 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_0032 6657e04d076f0a3b71175e6100826058 742 SUPERFAMILY SSF51735 194 332 1.97E-26 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0032 6657e04d076f0a3b71175e6100826058 742 Gene3D G3DSA:3.40.50.261 500 601 1.8E-8 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_0032 6657e04d076f0a3b71175e6100826058 742 Gene3D G3DSA:3.40.630.30 17 197 4.4E-38 T 11-10-2018 TO73_0032 6657e04d076f0a3b71175e6100826058 742 Gene3D G3DSA:3.40.50.720 198 324 4.5E-31 T 11-10-2018 TO73_0032 6657e04d076f0a3b71175e6100826058 742 SMART SM00881 202 301 1.5E-27 T 11-10-2018 IPR003781 CoA-binding GO:0048037 TO73_1613 8e16b0972a91ce2119cf9bf08de54fcd 630 SUPERFAMILY SSF56801 18 623 1.07E-150 T 11-10-2018 TO73_1613 8e16b0972a91ce2119cf9bf08de54fcd 630 Gene3D G3DSA:3.40.50.12780 72 501 2.9E-90 T 11-10-2018 TO73_1613 8e16b0972a91ce2119cf9bf08de54fcd 630 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 80 2.2E-9 T 11-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TO73_1613 8e16b0972a91ce2119cf9bf08de54fcd 630 Gene3D G3DSA:3.30.300.30 503 630 1.1E-27 T 11-10-2018 TO73_1613 8e16b0972a91ce2119cf9bf08de54fcd 630 Pfam PF13193 AMP-binding enzyme C-terminal domain 516 594 3.1E-22 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TO73_1613 8e16b0972a91ce2119cf9bf08de54fcd 630 Pfam PF00501 AMP-binding enzyme 82 507 7.2E-75 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_1613 8e16b0972a91ce2119cf9bf08de54fcd 630 ProSitePatterns PS00455 Putative AMP-binding domain signature. 249 260 - T 11-10-2018 IPR020845 AMP-binding, conserved site TO73_2853 04d9514488cf41922bb436eb0a56d082 138 SUPERFAMILY SSF88723 2 124 3.08E-20 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_2853 04d9514488cf41922bb436eb0a56d082 138 Pfam PF01850 PIN domain 4 124 9.6E-15 T 11-10-2018 IPR002716 PIN domain TO73_2853 04d9514488cf41922bb436eb0a56d082 138 Gene3D G3DSA:3.40.50.1010 3 129 7.8E-14 T 11-10-2018 TO73_2853 04d9514488cf41922bb436eb0a56d082 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 132 11.881 T 11-10-2018 IPR022907 VapC family GO:0004540 TO73_1290 9d76d492025aa5874f7d6d631fed29f8 254 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 27 250 30.007 T 11-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TO73_1290 9d76d492025aa5874f7d6d631fed29f8 254 SUPERFAMILY SSF51366 6 253 2.28E-74 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TO73_1290 9d76d492025aa5874f7d6d631fed29f8 254 Pfam PF00218 Indole-3-glycerol phosphate synthase 31 252 7.9E-70 T 11-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TO73_1290 9d76d492025aa5874f7d6d631fed29f8 254 Gene3D G3DSA:3.20.20.70 1 254 6.1E-96 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1290 9d76d492025aa5874f7d6d631fed29f8 254 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 10 254 31.236 T 11-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 Gene3D G3DSA:2.40.110.10 153 260 7.1E-31 T 11-10-2018 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 SUPERFAMILY SSF56645 46 257 3.27E-51 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 Gene3D G3DSA:1.10.540.10 41 149 8.1E-21 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 46 133 5.5E-15 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 155 167 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 Gene3D G3DSA:1.20.140.10 261 411 2.3E-54 T 11-10-2018 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 SUPERFAMILY SSF47203 256 407 4.51E-55 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 153 244 1.3E-19 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 256 403 9.6E-51 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 362 381 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_0830 a143f8bc9784e91eaa629f82ba0ed25e 412 PIRSF PIRSF016578 37 408 3.5E-23 T 11-10-2018 TO73_1369 34d63cd1372b0aaa84d96b30200cfda2 500 Pfam PF02446 4-alpha-glucanotransferase 11 477 1.1E-161 T 11-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TO73_1369 34d63cd1372b0aaa84d96b30200cfda2 500 SUPERFAMILY SSF51445 5 498 1.95E-171 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily TO73_1369 34d63cd1372b0aaa84d96b30200cfda2 500 Gene3D G3DSA:3.20.20.80 1 500 5.3E-219 T 11-10-2018 TO73_1369 34d63cd1372b0aaa84d96b30200cfda2 500 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 4 484 3.9E-103 T 11-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TO73_1047 980e59c660b3b62e481a3a54820a7e6f 524 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 213 4.5E-6 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_1047 980e59c660b3b62e481a3a54820a7e6f 524 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 174 191 4.5E-6 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_1047 980e59c660b3b62e481a3a54820a7e6f 524 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 104 118 4.5E-6 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_1047 980e59c660b3b62e481a3a54820a7e6f 524 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 138 156 4.5E-6 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_1047 980e59c660b3b62e481a3a54820a7e6f 524 SUPERFAMILY SSF52096 262 524 3.98E-89 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_1047 980e59c660b3b62e481a3a54820a7e6f 524 SUPERFAMILY SSF52096 16 267 1.06E-76 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_1047 980e59c660b3b62e481a3a54820a7e6f 524 Gene3D G3DSA:3.90.226.10 268 524 6.3E-93 T 11-10-2018 TO73_1047 980e59c660b3b62e481a3a54820a7e6f 524 Gene3D G3DSA:3.90.226.10 12 266 3.0E-91 T 11-10-2018 TO73_1047 980e59c660b3b62e481a3a54820a7e6f 524 Pfam PF01039 Carboxyl transferase domain 38 522 1.9E-185 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 410 477 4.2E-19 T 11-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 SUPERFAMILY SSF52954 277 400 2.27E-33 T 11-10-2018 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 SUPERFAMILY SSF64586 405 477 3.34E-23 T 11-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 SUPERFAMILY SSF55681 13 276 4.45E-78 T 11-10-2018 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 Gene3D G3DSA:3.40.50.800 283 400 2.5E-32 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 Gene3D G3DSA:3.30.110.30 404 477 1.4E-23 T 11-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 Gene3D G3DSA:3.30.930.10 1 282 2.5E-106 T 11-10-2018 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 Pfam PF03129 Anticodon binding domain 289 382 2.0E-16 T 11-10-2018 IPR004154 Anticodon-binding TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 477 45.276 T 11-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 102 270 9.3E-18 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 SMART SM00946 410 477 2.3E-29 T 11-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 8.3E-8 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 8.3E-8 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 8.3E-8 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 8.3E-8 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TO73_1904 dd65b57dad19f23336e1d7acda8b9b5b 477 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 477 9.5E-177 T 11-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TO73_2607 0f8e8ede17acc076e56f6c1368c788fb 116 Pfam PF13630 SdpI/YhfL protein family 30 102 3.7E-15 T 11-10-2018 IPR025962 SdpI/YhfL protein family TO73_2770 cbca5b5b50ebfa4dc81e5bb4e51b8582 125 PIRSF PIRSF002070 1 121 2.4E-14 T 11-10-2018 TO73_2770 cbca5b5b50ebfa4dc81e5bb4e51b8582 125 Pfam PF00436 Single-strand binding protein family 9 94 1.4E-14 T 11-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TO73_2770 cbca5b5b50ebfa4dc81e5bb4e51b8582 125 Gene3D G3DSA:2.40.50.140 1 110 8.2E-19 T 11-10-2018 TO73_2770 cbca5b5b50ebfa4dc81e5bb4e51b8582 125 SUPERFAMILY SSF50249 7 107 1.2E-20 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0939 161abf648963398aca15ddb8b58337ca 166 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 84 5.0E-9 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TO73_0939 161abf648963398aca15ddb8b58337ca 166 SMART SM00855 2 112 1.1E-5 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TO73_0939 161abf648963398aca15ddb8b58337ca 166 Gene3D G3DSA:3.40.50.1240 2 165 1.6E-26 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_0939 161abf648963398aca15ddb8b58337ca 166 SUPERFAMILY SSF53254 1 145 1.24E-19 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_1011 eceba21c8ae305163739057216f1ec67 287 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 4 262 3.5E-89 T 11-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 TO73_1011 eceba21c8ae305163739057216f1ec67 287 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 229 2.6E-35 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TO73_1011 eceba21c8ae305163739057216f1ec67 287 Gene3D G3DSA:3.40.1010.10 1 132 8.6E-34 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TO73_1011 eceba21c8ae305163739057216f1ec67 287 Gene3D G3DSA:3.30.950.10 133 260 6.2E-52 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TO73_1011 eceba21c8ae305163739057216f1ec67 287 SUPERFAMILY SSF53790 1 262 9.55E-56 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TO73_0161 ba0da3c1fb69ffdc808b3ffaa09e7fbf 180 Pfam PF00583 Acetyltransferase (GNAT) family 60 138 4.4E-13 T 11-10-2018 IPR000182 GNAT domain TO73_0161 ba0da3c1fb69ffdc808b3ffaa09e7fbf 180 SUPERFAMILY SSF55729 20 145 2.26E-23 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_0161 ba0da3c1fb69ffdc808b3ffaa09e7fbf 180 Gene3D G3DSA:3.40.630.30 23 167 1.2E-31 T 11-10-2018 TO73_1607 176677c0954828da526de53a39b0b0a5 381 SUPERFAMILY SSF53335 74 376 8.44E-71 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1607 176677c0954828da526de53a39b0b0a5 381 Gene3D G3DSA:3.30.750.80 67 171 8.9E-30 T 11-10-2018 TO73_1607 176677c0954828da526de53a39b0b0a5 381 SUPERFAMILY SSF88697 2 64 3.98E-30 T 11-10-2018 IPR015947 PUA-like superfamily TO73_1607 176677c0954828da526de53a39b0b0a5 381 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 163 342 1.9E-23 T 11-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TO73_1607 176677c0954828da526de53a39b0b0a5 381 Gene3D G3DSA:3.40.50.150 172 380 3.8E-71 T 11-10-2018 TO73_1607 176677c0954828da526de53a39b0b0a5 381 Gene3D G3DSA:2.30.130.10 1 66 1.4E-26 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 TO73_0581 6e8294ad36e0e8d42abd1c6940041c44 202 SUPERFAMILY SSF46785 120 196 1.07E-16 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0581 6e8294ad36e0e8d42abd1c6940041c44 202 SMART SM00419 139 187 8.1E-10 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_0581 6e8294ad36e0e8d42abd1c6940041c44 202 Pfam PF00027 Cyclic nucleotide-binding domain 8 87 4.8E-13 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain TO73_0581 6e8294ad36e0e8d42abd1c6940041c44 202 Pfam PF13545 Crp-like helix-turn-helix domain 122 193 2.4E-16 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_0581 6e8294ad36e0e8d42abd1c6940041c44 202 SUPERFAMILY SSF51206 6 108 1.07E-20 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like TO73_0581 6e8294ad36e0e8d42abd1c6940041c44 202 Gene3D G3DSA:1.10.10.10 118 202 5.4E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0581 6e8294ad36e0e8d42abd1c6940041c44 202 Gene3D G3DSA:2.60.120.10 1 117 1.1E-24 T 11-10-2018 IPR014710 RmlC-like jelly roll fold TO73_1683 cc223b08bc7d8c73028747f60457b589 185 Gene3D G3DSA:3.30.1360.40 32 106 4.7E-72 T 11-10-2018 TO73_1683 cc223b08bc7d8c73028747f60457b589 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 185 26.432 T 11-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 TO73_1683 cc223b08bc7d8c73028747f60457b589 185 SUPERFAMILY SSF55194 5 184 2.75E-69 T 11-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 TO73_1683 cc223b08bc7d8c73028747f60457b589 185 Pfam PF01765 Ribosome recycling factor 21 184 9.9E-66 T 11-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 TO73_1683 cc223b08bc7d8c73028747f60457b589 185 Gene3D G3DSA:1.10.132.20 13 183 4.7E-72 T 11-10-2018 TO73_1683 cc223b08bc7d8c73028747f60457b589 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 184 1.0E-68 T 11-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 TO73_1001 53e49906daee4aa66aea9e555b356bad 148 Gene3D G3DSA:2.30.110.10 1 148 7.5E-45 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TO73_1001 53e49906daee4aa66aea9e555b356bad 148 SMART SM00903 9 143 1.1E-48 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TO73_1001 53e49906daee4aa66aea9e555b356bad 148 Pfam PF01613 Flavin reductase like domain 9 144 1.2E-32 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TO73_1001 53e49906daee4aa66aea9e555b356bad 148 SUPERFAMILY SSF50475 5 144 1.32E-36 T 11-10-2018 TO73_2393 fb5c9a30fa4733c4073d51f89d30069d 211 Gene3D G3DSA:2.50.20.10 13 211 2.0E-60 T 11-10-2018 TO73_0395 6bf97a25edd1e8655f40b5926f26215f 150 SUPERFAMILY SSF52080 5 148 2.62E-40 T 11-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TO73_0395 6bf97a25edd1e8655f40b5926f26215f 150 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 148 19.68 T 11-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TO73_0395 6bf97a25edd1e8655f40b5926f26215f 150 ProSitePatterns PS00475 Ribosomal protein L15 signature. 113 142 - T 11-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0395 6bf97a25edd1e8655f40b5926f26215f 150 Gene3D G3DSA:3.100.10.10 72 150 1.9E-25 T 11-10-2018 TO73_0395 6bf97a25edd1e8655f40b5926f26215f 150 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 6.8E-35 T 11-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0395 6bf97a25edd1e8655f40b5926f26215f 150 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 146 4.0E-26 T 11-10-2018 IPR021131 Ribosomal protein L18e/L15P TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 Pfam PF00288 GHMP kinases N terminal domain 101 167 4.8E-15 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 107 118 - T 11-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 Gene3D G3DSA:3.30.70.890 188 338 1.2E-106 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 Pfam PF10509 Galactokinase galactose-binding signature 3 48 2.5E-15 T 11-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 SUPERFAMILY SSF54211 3 189 1.67E-51 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 Gene3D G3DSA:3.30.230.10 15 187 1.2E-106 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 SUPERFAMILY SSF55060 192 342 4.0E-43 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 TIGRFAM TIGR00131 gal_kin: galactokinase 3 342 5.8E-77 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 PRINTS PR00473 Galactokinase signature 19 37 4.9E-22 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 PRINTS PR00473 Galactokinase signature 246 260 4.9E-22 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 PRINTS PR00473 Galactokinase signature 98 116 4.9E-22 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 PIRSF PIRSF000530 1 346 6.6E-105 T 11-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 Pfam PF08544 GHMP kinases C terminal 263 342 7.6E-20 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 PRINTS PR00959 Mevalonate kinase family signature 105 127 1.3E-38 T 11-10-2018 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 PRINTS PR00959 Mevalonate kinase family signature 17 41 1.3E-38 T 11-10-2018 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 PRINTS PR00959 Mevalonate kinase family signature 148 167 1.3E-38 T 11-10-2018 TO73_1036 1064e6ee293ad3b2fe32e07848121d2d 347 PRINTS PR00959 Mevalonate kinase family signature 309 326 1.3E-38 T 11-10-2018 TO73_1296 1f4265d1d7a4a350d6a7063758bfed59 261 SMART SM00062 38 257 7.4E-70 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TO73_1296 1f4265d1d7a4a350d6a7063758bfed59 261 SMART SM00079 38 256 0.0062 T 11-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 TO73_1296 1f4265d1d7a4a350d6a7063758bfed59 261 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 256 2.6E-67 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TO73_1296 1f4265d1d7a4a350d6a7063758bfed59 261 Gene3D G3DSA:3.40.190.10 36 254 1.2E-89 T 11-10-2018 TO73_1296 1f4265d1d7a4a350d6a7063758bfed59 261 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 11-10-2018 IPR018313 Solute-binding protein family 3, conserved site TO73_1296 1f4265d1d7a4a350d6a7063758bfed59 261 Gene3D G3DSA:3.40.190.10 122 219 1.2E-89 T 11-10-2018 TO73_1296 1f4265d1d7a4a350d6a7063758bfed59 261 SUPERFAMILY SSF53850 9 257 1.21E-71 T 11-10-2018 TO73_2023 a490769ecd151bbbf47975bdb1f8e18e 222 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 9 203 8.5E-42 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 TO73_2023 a490769ecd151bbbf47975bdb1f8e18e 222 Hamap MF_02088 Probable queuosine precursor transporter. 1 209 17.575 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 TO73_2023 a490769ecd151bbbf47975bdb1f8e18e 222 Pfam PF02592 Putative vitamin uptake transporter 35 196 1.1E-49 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 TO73_0383 3f5f9570cf48329f6eed947aa5b57194 141 Gene3D G3DSA:3.90.1170.10 1 141 4.7E-54 T 11-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0383 3f5f9570cf48329f6eed947aa5b57194 141 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.3E-59 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0383 3f5f9570cf48329f6eed947aa5b57194 141 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.302 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0383 3f5f9570cf48329f6eed947aa5b57194 141 SUPERFAMILY SSF54686 1 138 3.92E-56 T 11-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0383 3f5f9570cf48329f6eed947aa5b57194 141 PRINTS PR00060 Ribosomal protein L16 signature 88 117 3.6E-35 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0383 3f5f9570cf48329f6eed947aa5b57194 141 PRINTS PR00060 Ribosomal protein L16 signature 24 36 3.6E-35 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0383 3f5f9570cf48329f6eed947aa5b57194 141 PRINTS PR00060 Ribosomal protein L16 signature 42 53 3.6E-35 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0383 3f5f9570cf48329f6eed947aa5b57194 141 PRINTS PR00060 Ribosomal protein L16 signature 58 87 3.6E-35 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0383 3f5f9570cf48329f6eed947aa5b57194 141 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 5.8E-49 T 11-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TO73_1886 6747e5b48f6d6d1834e31856a2f20625 119 Gene3D G3DSA:3.40.50.12740 1 118 9.9E-33 T 11-10-2018 TO73_1886 6747e5b48f6d6d1834e31856a2f20625 119 SUPERFAMILY SSF52172 1 117 7.68E-36 T 11-10-2018 IPR011006 CheY-like superfamily TO73_1886 6747e5b48f6d6d1834e31856a2f20625 119 Pfam PF00072 Response regulator receiver domain 3 112 2.5E-23 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1886 6747e5b48f6d6d1834e31856a2f20625 119 SMART SM00448 1 112 1.3E-37 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_2854 f9a08e96b44011dab7e4642a586767c2 83 Gene3D G3DSA:2.10.260.10 2 42 2.5E-6 T 11-10-2018 TO73_2854 f9a08e96b44011dab7e4642a586767c2 83 SUPERFAMILY SSF89447 2 41 8.2E-9 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily TO73_2854 f9a08e96b44011dab7e4642a586767c2 83 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 40 1.5E-8 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TO73_1314 c3b5d87fa9faa5756d83dd8a1d6c54fb 379 SUPERFAMILY SSF56024 238 378 1.59E-34 T 11-10-2018 TO73_1314 c3b5d87fa9faa5756d83dd8a1d6c54fb 379 Pfam PF13091 PLD-like domain 252 373 6.0E-27 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TO73_1314 c3b5d87fa9faa5756d83dd8a1d6c54fb 379 Pfam PF13091 PLD-like domain 64 213 5.5E-18 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TO73_1314 c3b5d87fa9faa5756d83dd8a1d6c54fb 379 SMART SM00155 318 345 0.0047 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TO73_1314 c3b5d87fa9faa5756d83dd8a1d6c54fb 379 SMART SM00155 159 186 2.1E-5 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TO73_1314 c3b5d87fa9faa5756d83dd8a1d6c54fb 379 Gene3D G3DSA:3.30.870.10 39 220 4.3E-38 T 11-10-2018 TO73_1314 c3b5d87fa9faa5756d83dd8a1d6c54fb 379 SUPERFAMILY SSF56024 52 214 1.06E-27 T 11-10-2018 TO73_1314 c3b5d87fa9faa5756d83dd8a1d6c54fb 379 Gene3D G3DSA:3.30.870.10 233 378 1.5E-39 T 11-10-2018 TO73_0574 703507dca0b004788830d8f2606478a0 466 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 310 321 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_0574 703507dca0b004788830d8f2606478a0 466 SUPERFAMILY SSF46548 282 389 6.28E-17 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TO73_0574 703507dca0b004788830d8f2606478a0 466 Pfam PF11870 Domain of unknown function (DUF3390) 393 458 6.4E-12 T 11-10-2018 IPR024569 4Fe-4S binding protein, C-terminal TO73_0574 703507dca0b004788830d8f2606478a0 466 Pfam PF02589 LUD domain 68 291 3.7E-46 T 11-10-2018 IPR003741 LUD domain TO73_0574 703507dca0b004788830d8f2606478a0 466 SUPERFAMILY SSF100950 63 292 7.11E-38 T 11-10-2018 IPR037171 NagB/RpiA transferase-like TO73_0574 703507dca0b004788830d8f2606478a0 466 Gene3D G3DSA:3.40.50.10420 128 292 3.7E-13 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TO73_0574 703507dca0b004788830d8f2606478a0 466 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 22 420 3.5E-138 T 11-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 TO73_0574 703507dca0b004788830d8f2606478a0 466 Pfam PF13183 4Fe-4S dicluster domain 308 374 2.8E-10 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_0396 a8e255344890d0a09410f824c09078e2 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 177 200 1.7E-77 T 11-10-2018 TO73_0396 a8e255344890d0a09410f824c09078e2 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 151 176 1.7E-77 T 11-10-2018 TO73_0396 a8e255344890d0a09410f824c09078e2 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 1.7E-77 T 11-10-2018 TO73_0396 a8e255344890d0a09410f824c09078e2 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.7E-77 T 11-10-2018 TO73_0396 a8e255344890d0a09410f824c09078e2 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 111 134 1.7E-77 T 11-10-2018 TO73_0396 a8e255344890d0a09410f824c09078e2 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 1.7E-77 T 11-10-2018 TO73_0396 a8e255344890d0a09410f824c09078e2 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 1.7E-77 T 11-10-2018 TO73_0396 a8e255344890d0a09410f824c09078e2 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 70 90 1.7E-77 T 11-10-2018 TO73_0396 a8e255344890d0a09410f824c09078e2 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 1.7E-77 T 11-10-2018 TO73_0396 a8e255344890d0a09410f824c09078e2 438 PIRSF PIRSF004557 1 434 1.1E-112 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TO73_0396 a8e255344890d0a09410f824c09078e2 438 SUPERFAMILY SSF103491 1 419 2.62E-113 T 11-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TO73_0396 a8e255344890d0a09410f824c09078e2 438 Pfam PF00344 SecY translocase 71 411 1.6E-102 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TO73_0396 a8e255344890d0a09410f824c09078e2 438 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 424 3.6E-111 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TO73_0396 a8e255344890d0a09410f824c09078e2 438 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 428 29.106 T 11-10-2018 IPR026593 Protein translocase subunit SecY TO73_0396 a8e255344890d0a09410f824c09078e2 438 Gene3D G3DSA:1.10.3370.10 1 424 3.9E-183 T 11-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 Gene3D G3DSA:3.90.640.10 179 254 9.6E-126 T 11-10-2018 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 125 144 1.5E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 1.5E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 180 200 1.5E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 1.5E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 1.5E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 Pfam PF06723 MreB/Mbl protein 5 329 1.3E-137 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 SUPERFAMILY SSF53067 143 328 1.3E-49 T 11-10-2018 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 Gene3D G3DSA:3.30.420.40 7 322 9.6E-126 T 11-10-2018 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 Gene3D G3DSA:3.30.420.40 147 312 9.6E-126 T 11-10-2018 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 SUPERFAMILY SSF53067 6 141 2.79E-33 T 11-10-2018 TO73_0320 bb371c99932b86205326baecfb8fbcb9 343 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 5 330 1.3E-140 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TO73_0884 04e567e85ba4089ee7cffd323d9e75d6 206 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 3 203 26.12 T 11-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TO73_0884 04e567e85ba4089ee7cffd323d9e75d6 206 SUPERFAMILY SSF51391 4 201 1.26E-64 T 11-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TO73_0884 04e567e85ba4089ee7cffd323d9e75d6 206 Gene3D G3DSA:3.20.20.70 2 203 6.7E-66 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0884 04e567e85ba4089ee7cffd323d9e75d6 206 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 4 197 6.9E-59 T 11-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TO73_0884 04e567e85ba4089ee7cffd323d9e75d6 206 Pfam PF02581 Thiamine monophosphate synthase 5 185 1.1E-56 T 11-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TO73_1555 e226a98b51b85e1ff6fe5faae9461c3b 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TO73_1555 e226a98b51b85e1ff6fe5faae9461c3b 306 Gene3D G3DSA:3.40.1190.20 1 305 4.7E-71 T 11-10-2018 IPR029056 Ribokinase-like TO73_1555 e226a98b51b85e1ff6fe5faae9461c3b 306 PRINTS PR00990 Ribokinase signature 32 51 1.3E-8 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TO73_1555 e226a98b51b85e1ff6fe5faae9461c3b 306 PRINTS PR00990 Ribokinase signature 104 117 1.3E-8 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TO73_1555 e226a98b51b85e1ff6fe5faae9461c3b 306 PRINTS PR00990 Ribokinase signature 219 230 1.3E-8 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TO73_1555 e226a98b51b85e1ff6fe5faae9461c3b 306 PRINTS PR00990 Ribokinase signature 5 26 1.3E-8 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TO73_1555 e226a98b51b85e1ff6fe5faae9461c3b 306 SUPERFAMILY SSF53613 1 298 8.42E-70 T 11-10-2018 IPR029056 Ribokinase-like TO73_1555 e226a98b51b85e1ff6fe5faae9461c3b 306 Pfam PF00294 pfkB family carbohydrate kinase 4 292 1.1E-49 T 11-10-2018 IPR011611 Carbohydrate kinase PfkB TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 Pfam PF02464 Competence-damaged protein 248 392 1.7E-43 T 11-10-2018 IPR008136 CinA, C-terminal TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 PIRSF PIRSF006728 1 394 4.8E-110 T 11-10-2018 IPR008135 Competence-induced protein CinA TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 SMART SM00852 5 172 1.1E-34 T 11-10-2018 IPR001453 MoaB/Mog domain TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 Pfam PF00994 Probable molybdopterin binding domain 6 168 6.9E-31 T 11-10-2018 IPR001453 MoaB/Mog domain TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 SUPERFAMILY SSF142433 241 393 2.62E-41 T 11-10-2018 IPR036653 CinA-like, C-terminal TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 Gene3D G3DSA:3.90.950.20 248 394 1.5E-54 T 11-10-2018 IPR036653 CinA-like, C-terminal TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 Gene3D G3DSA:3.30.70.2860 174 247 2.5E-41 T 11-10-2018 TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 394 126.294 T 11-10-2018 IPR008135 Competence-induced protein CinA TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 SUPERFAMILY SSF53218 3 200 7.72E-34 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 392 1.2E-83 T 11-10-2018 IPR008135 Competence-induced protein CinA TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 Gene3D G3DSA:3.40.980.10 1 172 2.4E-52 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily TO73_0316 8a7db1c3ced9e8533b2087ebec2c9669 394 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 255 392 2.1E-28 T 11-10-2018 IPR008136 CinA, C-terminal TO73_0449 54f344ab35167f823b8574d86db19d35 104 Pfam PF01934 Protein of unknown function DUF86 1 96 1.3E-31 T 11-10-2018 IPR008201 Protein of unknown function DUF86 TO73_1926 01c5213943ca739802a9fb813cd5e8c6 209 SMART SM00563 39 151 2.8E-34 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TO73_1926 01c5213943ca739802a9fb813cd5e8c6 209 Pfam PF01553 Acyltransferase 26 148 1.1E-25 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TO73_1926 01c5213943ca739802a9fb813cd5e8c6 209 SUPERFAMILY SSF69593 14 205 4.58E-50 T 11-10-2018 TO73_0744 638add738c0c44fe9cae06af84ed8c03 324 PIRSF PIRSF036979 35 315 7.7E-61 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 TO73_0744 638add738c0c44fe9cae06af84ed8c03 324 SUPERFAMILY SSF52768 50 314 5.04E-71 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily TO73_0744 638add738c0c44fe9cae06af84ed8c03 324 TIGRFAM TIGR01230 agmatinase: agmatinase 43 311 7.5E-65 T 11-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 TO73_0744 638add738c0c44fe9cae06af84ed8c03 324 Gene3D G3DSA:3.40.800.10 34 315 2.2E-72 T 11-10-2018 TO73_0744 638add738c0c44fe9cae06af84ed8c03 324 Pfam PF00491 Arginase family 51 310 3.3E-65 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 TO73_2345 4d3cd24c4cdb9e941843b8bc6865407d 430 Pfam PF00909 Ammonium Transporter Family 16 405 7.3E-117 T 11-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 TO73_2345 4d3cd24c4cdb9e941843b8bc6865407d 430 ProSitePatterns PS01219 Ammonium transporters signature. 162 187 - T 11-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 TO73_2345 4d3cd24c4cdb9e941843b8bc6865407d 430 SUPERFAMILY SSF111352 9 385 3.01E-120 T 11-10-2018 TO73_2345 4d3cd24c4cdb9e941843b8bc6865407d 430 Gene3D G3DSA:1.10.3430.10 9 410 6.5E-136 T 11-10-2018 IPR029020 Ammonium/urea transporter TO73_2345 4d3cd24c4cdb9e941843b8bc6865407d 430 TIGRFAM TIGR00836 amt: ammonium transporter 13 405 8.7E-130 T 11-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 TO73_0960 229c51ac3ca5a759b2914eaff5712e5e 617 SUPERFAMILY SSF56801 4 590 1.57E-107 T 11-10-2018 TO73_0960 229c51ac3ca5a759b2914eaff5712e5e 617 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 11-10-2018 IPR020845 AMP-binding, conserved site TO73_0960 229c51ac3ca5a759b2914eaff5712e5e 617 Gene3D G3DSA:3.40.50.12780 310 454 3.5E-39 T 11-10-2018 TO73_0960 229c51ac3ca5a759b2914eaff5712e5e 617 Pfam PF00501 AMP-binding enzyme 12 455 7.6E-80 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_0960 229c51ac3ca5a759b2914eaff5712e5e 617 Gene3D G3DSA:3.40.50.12780 2 309 2.3E-44 T 11-10-2018 TO73_1487 32d3a0aec1eccbba4f5a6ae758caa13e 312 SUPERFAMILY SSF51735 102 280 9.01E-60 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1487 32d3a0aec1eccbba4f5a6ae758caa13e 312 Gene3D G3DSA:3.40.50.720 98 279 2.2E-125 T 11-10-2018 TO73_1487 32d3a0aec1eccbba4f5a6ae758caa13e 312 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 175 - T 11-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TO73_1487 32d3a0aec1eccbba4f5a6ae758caa13e 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 280 4.5E-60 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TO73_1487 32d3a0aec1eccbba4f5a6ae758caa13e 312 Gene3D G3DSA:3.40.50.720 8 304 2.2E-125 T 11-10-2018 TO73_1487 32d3a0aec1eccbba4f5a6ae758caa13e 312 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TO73_1487 32d3a0aec1eccbba4f5a6ae758caa13e 312 SUPERFAMILY SSF52283 2 134 6.05E-37 T 11-10-2018 TO73_1487 32d3a0aec1eccbba4f5a6ae758caa13e 312 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TO73_1487 32d3a0aec1eccbba4f5a6ae758caa13e 312 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 311 2.9E-37 T 11-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TO73_1280 dceb7d47f25bc39224bebf73d77e5c9f 228 SUPERFAMILY SSF75217 68 223 6.28E-45 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases TO73_1280 dceb7d47f25bc39224bebf73d77e5c9f 228 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 18 223 6.4E-45 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TO73_1280 dceb7d47f25bc39224bebf73d77e5c9f 228 Gene3D G3DSA:3.40.1280.10 67 228 5.0E-60 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TO73_1280 dceb7d47f25bc39224bebf73d77e5c9f 228 Gene3D G3DSA:2.40.240.20 1 66 6.1E-30 T 11-10-2018 TO73_1280 dceb7d47f25bc39224bebf73d77e5c9f 228 PIRSF PIRSF015601 11 227 4.6E-54 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TO73_1280 dceb7d47f25bc39224bebf73d77e5c9f 228 SUPERFAMILY SSF88697 4 66 8.12E-30 T 11-10-2018 IPR015947 PUA-like superfamily TO73_1280 dceb7d47f25bc39224bebf73d77e5c9f 228 Pfam PF04452 RNA methyltransferase 18 223 2.0E-54 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 Gene3D G3DSA:1.10.540.10 1 118 3.5E-38 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 210 3.7E-26 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 Gene3D G3DSA:1.20.140.10 228 371 8.2E-56 T 11-10-2018 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 SUPERFAMILY SSF47203 220 371 3.87E-58 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 PIRSF PIRSF016578 1 119 2.8E-7 T 11-10-2018 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 PIRSF PIRSF016578 126 370 1.5E-17 T 11-10-2018 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 6.0E-33 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 SUPERFAMILY SSF56645 2 235 2.49E-80 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 Gene3D G3DSA:2.40.110.10 119 227 2.7E-40 T 11-10-2018 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 329 348 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_0089 0de6039a6f5a7f64cef5c0b2034590e0 372 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 222 370 1.7E-52 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 Pfam PF01713 Smr domain 668 743 1.3E-19 T 11-10-2018 IPR002625 Smr domain TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 SUPERFAMILY SSF52540 284 491 2.62E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 SMART SM00534 308 492 1.2E-70 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 Gene3D G3DSA:3.40.50.300 277 576 2.1E-76 T 11-10-2018 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 PIRSF PIRSF005814 1 743 8.1E-202 T 11-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 Gene3D G3DSA:3.30.1370.110 661 743 3.0E-24 T 11-10-2018 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 389 405 - T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 SMART SM00533 8 297 3.4E-6 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 Pfam PF00488 MutS domain V 312 490 1.4E-37 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 TIGRFAM TIGR01069 mutS2: MutS2 family protein 3 743 9.5E-175 T 11-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 1 742 19.177 T 11-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 SMART SM00463 665 743 5.4E-19 T 11-10-2018 IPR002625 Smr domain TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 SUPERFAMILY SSF160443 667 743 3.79E-10 T 11-10-2018 IPR036063 Smr domain superfamily TO73_2107 5ff469183f3d3db6e2a04074234e6d74 752 SUPERFAMILY SSF48334 20 273 1.1E-21 T 11-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily TO73_2342 f536634471345b3608ef68f2b1837e1b 361 Gene3D G3DSA:3.40.800.20 69 358 3.7E-66 T 11-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_2342 f536634471345b3608ef68f2b1837e1b 361 Pfam PF00850 Histone deacetylase domain 93 341 6.4E-47 T 11-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_2342 f536634471345b3608ef68f2b1837e1b 361 PRINTS PR01270 Histone deacetylase superfamily signature 212 227 1.5E-12 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_2342 f536634471345b3608ef68f2b1837e1b 361 PRINTS PR01270 Histone deacetylase superfamily signature 285 295 1.5E-12 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_2342 f536634471345b3608ef68f2b1837e1b 361 PRINTS PR01270 Histone deacetylase superfamily signature 178 201 1.5E-12 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_2342 f536634471345b3608ef68f2b1837e1b 361 SUPERFAMILY SSF52768 72 341 3.64E-77 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily TO73_0910 77beac4a82264a138533b6b7a84bcd89 553 Pfam PF00501 AMP-binding enzyme 40 452 1.5E-105 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_0910 77beac4a82264a138533b6b7a84bcd89 553 Pfam PF13193 AMP-binding enzyme C-terminal domain 461 538 1.2E-19 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TO73_0910 77beac4a82264a138533b6b7a84bcd89 553 SUPERFAMILY SSF56801 22 550 1.83E-154 T 11-10-2018 TO73_0910 77beac4a82264a138533b6b7a84bcd89 553 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 11-10-2018 IPR020845 AMP-binding, conserved site TO73_0910 77beac4a82264a138533b6b7a84bcd89 553 Gene3D G3DSA:3.30.300.310 449 552 1.6E-30 T 11-10-2018 TO73_0910 77beac4a82264a138533b6b7a84bcd89 553 Gene3D G3DSA:3.40.50.12780 18 448 2.0E-117 T 11-10-2018 TO73_2067 d2fe36f3dd0a9dd0324a1a832e489c14 375 Gene3D G3DSA:2.40.30.130 1 90 7.6E-18 T 11-10-2018 TO73_2067 d2fe36f3dd0a9dd0324a1a832e489c14 375 SUPERFAMILY SSF50447 3 90 3.53E-12 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_2067 d2fe36f3dd0a9dd0324a1a832e489c14 375 Pfam PF01411 tRNA synthetases class II (A) 18 94 1.5E-10 T 11-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TO73_2067 d2fe36f3dd0a9dd0324a1a832e489c14 375 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 185 227 4.9E-8 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TO73_2067 d2fe36f3dd0a9dd0324a1a832e489c14 375 Gene3D G3DSA:3.30.980.10 91 244 5.5E-39 T 11-10-2018 TO73_2067 d2fe36f3dd0a9dd0324a1a832e489c14 375 SMART SM00863 185 227 1.0E-11 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TO73_2067 d2fe36f3dd0a9dd0324a1a832e489c14 375 SUPERFAMILY SSF55186 94 234 3.53E-30 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TO73_2388 f2b88ce99e2efb4b1cd346806bcc2dbc 676 Pfam PF13567 Domain of unknown function (DUF4131) 98 138 6.5E-8 T 11-10-2018 IPR025405 Domain of unknown function DUF4131 TO73_2388 f2b88ce99e2efb4b1cd346806bcc2dbc 676 SUPERFAMILY SSF56281 443 670 7.54E-34 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_2388 f2b88ce99e2efb4b1cd346806bcc2dbc 676 Pfam PF00753 Metallo-beta-lactamase superfamily 451 634 4.0E-9 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_2388 f2b88ce99e2efb4b1cd346806bcc2dbc 676 Pfam PF03772 Competence protein 168 413 1.6E-42 T 11-10-2018 IPR004477 ComEC/Rec2-related protein TO73_2388 f2b88ce99e2efb4b1cd346806bcc2dbc 676 Gene3D G3DSA:3.60.15.10 445 673 3.1E-53 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_2388 f2b88ce99e2efb4b1cd346806bcc2dbc 676 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 188 354 1.0E-22 T 11-10-2018 IPR004477 ComEC/Rec2-related protein TO73_0327 18804ad15cb5fde61c91636b2a23f12d 280 Gene3D G3DSA:3.40.50.1820 1 277 1.6E-84 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0327 18804ad15cb5fde61c91636b2a23f12d 280 SUPERFAMILY SSF53474 4 273 3.38E-45 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0327 18804ad15cb5fde61c91636b2a23f12d 280 Pfam PF12697 Alpha/beta hydrolase family 28 265 4.8E-18 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_0327 18804ad15cb5fde61c91636b2a23f12d 280 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 55 66 1.5E-8 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TO73_0327 18804ad15cb5fde61c91636b2a23f12d 280 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 28 36 1.5E-8 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TO73_0327 18804ad15cb5fde61c91636b2a23f12d 280 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 99 113 1.5E-8 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TO73_0996 f342eb5120b2a2b0ad6f56a9cb8c9e12 238 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 233 4.9E-5 T 11-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TO73_0996 f342eb5120b2a2b0ad6f56a9cb8c9e12 238 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0996 f342eb5120b2a2b0ad6f56a9cb8c9e12 238 SUPERFAMILY SSF52540 2 233 2.93E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0996 f342eb5120b2a2b0ad6f56a9cb8c9e12 238 Gene3D G3DSA:3.40.50.300 1 235 2.9E-59 T 11-10-2018 TO73_0996 f342eb5120b2a2b0ad6f56a9cb8c9e12 238 Pfam PF00005 ABC transporter 18 162 1.2E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0996 f342eb5120b2a2b0ad6f56a9cb8c9e12 238 SMART SM00382 26 211 9.0E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 SUPERFAMILY SSF52540 26 218 1.03E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 Gene3D G3DSA:1.10.8.60 6 233 2.2E-92 T 11-10-2018 TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 228 315 1.6E-6 T 11-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 SMART SM00382 35 181 1.9E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 290 6.6E-106 T 11-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 Gene3D G3DSA:3.40.50.300 11 173 2.2E-92 T 11-10-2018 TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 Gene3D G3DSA:1.10.40.100 498 543 2.3E-28 T 11-10-2018 TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 120 138 4.4E-6 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 39 57 4.4E-6 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_2159 ae4a5a83e03d821437e63febec6859ce 543 Pfam PF13177 DNA polymerase III, delta subunit 18 174 1.6E-42 T 11-10-2018 TO73_0434 2a219422566b0631b50e75303f56c5b5 520 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0434 2a219422566b0631b50e75303f56c5b5 520 PIRSF PIRSF003128 1 520 4.3E-130 T 11-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TO73_0434 2a219422566b0631b50e75303f56c5b5 520 SUPERFAMILY SSF52540 1 485 4.49E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0434 2a219422566b0631b50e75303f56c5b5 520 Gene3D G3DSA:3.40.50.300 293 519 1.9E-45 T 11-10-2018 TO73_0434 2a219422566b0631b50e75303f56c5b5 520 Gene3D G3DSA:3.40.50.300 1 271 1.3E-34 T 11-10-2018 TO73_0434 2a219422566b0631b50e75303f56c5b5 520 Pfam PF02463 RecF/RecN/SMC N terminal domain 81 480 9.7E-12 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TO73_2341 ba18839f529dd7818e5d4b8d13c19b95 284 SUPERFAMILY SSF55729 116 274 8.75E-25 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_2341 ba18839f529dd7818e5d4b8d13c19b95 284 Pfam PF13673 Acetyltransferase (GNAT) domain 174 270 1.1E-15 T 11-10-2018 IPR000182 GNAT domain TO73_2341 ba18839f529dd7818e5d4b8d13c19b95 284 Gene3D G3DSA:3.40.630.30 153 280 5.9E-23 T 11-10-2018 TO73_2341 ba18839f529dd7818e5d4b8d13c19b95 284 Gene3D G3DSA:3.40.630.30 1 130 1.4E-8 T 11-10-2018 TO73_2341 ba18839f529dd7818e5d4b8d13c19b95 284 SUPERFAMILY SSF55729 1 131 4.58E-11 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_1700 8172f37933dde2ccf5ef476c3326b2e6 124 ProSitePatterns PS00380 Rhodanese signature 1. 51 62 - T 11-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TO73_1700 8172f37933dde2ccf5ef476c3326b2e6 124 SUPERFAMILY SSF52821 8 124 4.98E-38 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1700 8172f37933dde2ccf5ef476c3326b2e6 124 SMART SM00450 27 121 8.4E-29 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1700 8172f37933dde2ccf5ef476c3326b2e6 124 Pfam PF00581 Rhodanese-like domain 29 115 1.8E-19 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1700 8172f37933dde2ccf5ef476c3326b2e6 124 Gene3D G3DSA:3.40.250.10 29 124 3.4E-34 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 Pfam PF00334 Nucleoside diphosphate kinase 2 135 2.7E-58 T 11-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 Gene3D G3DSA:3.30.70.141 1 137 2.8E-62 T 11-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 SMART SM00562 1 137 1.5E-84 T 11-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 7.6E-48 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 7.6E-48 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 7.6E-48 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 7.6E-48 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 7.6E-48 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 37.357 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_2170 7747cf54beb82374ea251d52b39a0daf 137 SUPERFAMILY SSF54919 1 136 8.77E-59 T 11-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 SUPERFAMILY SSF51735 1 169 4.67E-42 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0277 6ddee7504374c3229be7425171df1aeb 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 55 82 6.3E-40 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 5 22 6.3E-40 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 190 214 6.3E-40 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 126 146 6.3E-40 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 165 189 6.3E-40 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 230 247 6.3E-40 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 SUPERFAMILY SSF48179 172 321 1.38E-46 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 180 201 - T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 172 310 7.1E-46 T 11-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 PIRSF PIRSF000114 1 321 6.5E-83 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 147 3.4E-36 T 11-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 Gene3D G3DSA:3.40.50.720 1 179 1.1E-48 T 11-10-2018 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 312 32.261 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TO73_0277 6ddee7504374c3229be7425171df1aeb 321 Gene3D G3DSA:1.10.1040.10 181 321 2.1E-44 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TO73_0466 ff7833590bc25690d5430746c115de97 296 SUPERFAMILY SSF52540 3 268 3.21E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0466 ff7833590bc25690d5430746c115de97 296 Gene3D G3DSA:1.10.8.300 187 292 5.8E-16 T 11-10-2018 TO73_0466 ff7833590bc25690d5430746c115de97 296 PIRSF PIRSF002849 1 296 1.9E-108 T 11-10-2018 TO73_0466 ff7833590bc25690d5430746c115de97 296 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 33 160 1.4E-59 T 11-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TO73_0466 ff7833590bc25690d5430746c115de97 296 Gene3D G3DSA:3.40.50.300 14 178 1.7E-44 T 11-10-2018 TO73_0466 ff7833590bc25690d5430746c115de97 296 SMART SM00382 30 169 1.3E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 Gene3D G3DSA:3.40.1110.10 309 450 2.9E-157 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 SUPERFAMILY SSF56784 297 655 3.01E-58 T 11-10-2018 IPR036412 HAD-like superfamily TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 Gene3D G3DSA:3.40.50.1000 296 579 2.9E-157 T 11-10-2018 IPR023214 HAD superfamily TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 Gene3D G3DSA:1.20.1110.10 33 685 2.9E-157 T 11-10-2018 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 SUPERFAMILY SSF81653 102 198 1.44E-31 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 301 307 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 SUPERFAMILY SSF81660 306 445 1.02E-23 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 571 596 1.4E-20 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 511 527 1.4E-20 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 539 555 1.4E-20 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 411 429 1.4E-20 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 Pfam PF00122 E1-E2 ATPase 99 279 2.9E-56 T 11-10-2018 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 SUPERFAMILY SSF81665 2 801 1.83E-98 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 51 2.9E-17 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 Pfam PF00689 Cation transporting ATPase, C-terminus 635 794 7.4E-29 T 11-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 Gene3D G3DSA:2.70.150.10 4 201 2.9E-157 T 11-10-2018 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 Pfam PF00702 haloacid dehalogenase-like hydrolase 296 553 2.9E-28 T 11-10-2018 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 71 493 1.5E-69 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 510 623 6.2E-35 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 SMART SM00831 2 57 1.4E-15 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 558 4.9E-40 T 11-10-2018 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 443 454 4.9E-40 T 11-10-2018 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 149 163 4.9E-40 T 11-10-2018 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 465 475 4.9E-40 T 11-10-2018 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 563 575 4.9E-40 T 11-10-2018 TO73_0729 5c5b71a9a79a6e8e2dd97a0afe3d6661 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 299 313 4.9E-40 T 11-10-2018 TO73_0834 75f82607470250a337d54946798512fe 861 Gene3D G3DSA:3.40.50.740 124 650 0.0 T 11-10-2018 TO73_0834 75f82607470250a337d54946798512fe 861 Gene3D G3DSA:3.30.200.200 13 687 0.0 T 11-10-2018 TO73_0834 75f82607470250a337d54946798512fe 861 Pfam PF00384 Molybdopterin oxidoreductase 123 593 1.4E-36 T 11-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_0834 75f82607470250a337d54946798512fe 861 Pfam PF01568 Molydopterin dinucleotide binding domain 729 834 8.2E-24 T 11-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TO73_0834 75f82607470250a337d54946798512fe 861 TIGRFAM TIGR02693 arsenite_ox_L: arsenite oxidase, large subunit 10 841 0.0 T 11-10-2018 IPR014066 Arsenite oxidase, large subunit MetaCyc: PWY-7429 TO73_0834 75f82607470250a337d54946798512fe 861 SUPERFAMILY SSF53706 10 703 1.05E-137 T 11-10-2018 TO73_0834 75f82607470250a337d54946798512fe 861 Gene3D G3DSA:2.40.40.20 717 852 1.3E-48 T 11-10-2018 TO73_0834 75f82607470250a337d54946798512fe 861 SUPERFAMILY SSF50692 691 841 9.49E-37 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TO73_0834 75f82607470250a337d54946798512fe 861 Gene3D G3DSA:3.40.228.10 207 710 0.0 T 11-10-2018 TO73_2066 b488c702990b69a26cb6872ab0f94e11 55 Gene3D G3DSA:1.20.120.330 4 53 3.5E-12 T 11-10-2018 TO73_2066 b488c702990b69a26cb6872ab0f94e11 55 SUPERFAMILY SSF81593 6 46 1.49E-11 T 11-10-2018 TO73_2066 b488c702990b69a26cb6872ab0f94e11 55 Pfam PF05168 HEPN domain 10 45 5.6E-11 T 11-10-2018 IPR007842 HEPN domain TO73_2785 d77b55eb48f478494d4705424e56ca6a 123 SUPERFAMILY SSF143602 3 105 3.14E-12 T 11-10-2018 IPR037236 STIV B116-like TO73_2785 d77b55eb48f478494d4705424e56ca6a 123 Gene3D G3DSA:3.40.50.11170 1 122 1.6E-16 T 11-10-2018 IPR037236 STIV B116-like TO73_2785 d77b55eb48f478494d4705424e56ca6a 123 Pfam PF08960 Domain of unknown function (DUF1874) 3 105 1.9E-9 T 11-10-2018 IPR015055 Protein of unknown function DUF1874 TO73_0313 b4467f5c46f0626cccf2dcf79bc4c221 209 SUPERFAMILY SSF56784 1 203 1.49E-51 T 11-10-2018 IPR036412 HAD-like superfamily TO73_0313 b4467f5c46f0626cccf2dcf79bc4c221 209 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.0E-6 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0313 b4467f5c46f0626cccf2dcf79bc4c221 209 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 95 108 1.0E-6 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0313 b4467f5c46f0626cccf2dcf79bc4c221 209 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 162 1.0E-6 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0313 b4467f5c46f0626cccf2dcf79bc4c221 209 Gene3D G3DSA:3.40.50.1000 6 197 2.2E-51 T 11-10-2018 IPR023214 HAD superfamily TO73_0313 b4467f5c46f0626cccf2dcf79bc4c221 209 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 179 4.1E-26 T 11-10-2018 TO73_0313 b4467f5c46f0626cccf2dcf79bc4c221 209 Gene3D G3DSA:1.10.150.240 17 81 2.2E-51 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TO73_0313 b4467f5c46f0626cccf2dcf79bc4c221 209 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 64 179 4.1E-17 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0313 b4467f5c46f0626cccf2dcf79bc4c221 209 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 87 154 4.9E-7 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_1255 291a5debac87f8851f94113ca43f4e64 522 Gene3D G3DSA:3.50.50.60 1 84 1.1E-19 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1255 291a5debac87f8851f94113ca43f4e64 522 Gene3D G3DSA:3.50.50.60 212 308 1.5E-22 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1255 291a5debac87f8851f94113ca43f4e64 522 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 3 514 1.0E-162 T 11-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 TO73_1255 291a5debac87f8851f94113ca43f4e64 522 Pfam PF01593 Flavin containing amine oxidoreductase 11 289 6.8E-26 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TO73_1255 291a5debac87f8851f94113ca43f4e64 522 SUPERFAMILY SSF51905 1 508 1.5E-70 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1164 103b67b719cc7f7896da54b04e66babe 96 PRINTS PR01249 Ribosomal protein L31 signature 27 44 2.6E-21 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1164 103b67b719cc7f7896da54b04e66babe 96 PRINTS PR01249 Ribosomal protein L31 signature 55 70 2.6E-21 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1164 103b67b719cc7f7896da54b04e66babe 96 PRINTS PR01249 Ribosomal protein L31 signature 70 88 2.6E-21 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1164 103b67b719cc7f7896da54b04e66babe 96 ProSitePatterns PS01143 Ribosomal protein L31 signature. 59 80 - T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1164 103b67b719cc7f7896da54b04e66babe 96 SUPERFAMILY SSF143800 27 90 1.18E-24 T 11-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1164 103b67b719cc7f7896da54b04e66babe 96 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 26 92 28.404 T 11-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1164 103b67b719cc7f7896da54b04e66babe 96 Gene3D G3DSA:2.30.170.50 26 93 1.8E-29 T 11-10-2018 TO73_1164 103b67b719cc7f7896da54b04e66babe 96 TIGRFAM TIGR00105 L31: ribosomal protein bL31 27 89 2.0E-26 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1164 103b67b719cc7f7896da54b04e66babe 96 Pfam PF01197 Ribosomal protein L31 27 89 1.9E-29 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0492 6d77dfbce8e94876b31093a594571f1f 105 Pfam PF02575 YbaB/EbfC DNA-binding family 8 96 1.1E-22 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TO73_0492 6d77dfbce8e94876b31093a594571f1f 105 Gene3D G3DSA:3.30.1310.10 1 103 6.4E-25 T 11-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TO73_0492 6d77dfbce8e94876b31093a594571f1f 105 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 95 7.3E-16 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TO73_0492 6d77dfbce8e94876b31093a594571f1f 105 SUPERFAMILY SSF82607 3 96 2.88E-21 T 11-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TO73_0492 6d77dfbce8e94876b31093a594571f1f 105 PIRSF PIRSF004555 1 105 3.9E-27 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TO73_0492 6d77dfbce8e94876b31093a594571f1f 105 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 96 19.294 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TO73_2297 5c22e2376047110f8edbc1a63b165a9b 106 Gene3D G3DSA:3.30.460.10 10 106 8.1E-25 T 11-10-2018 TO73_2297 5c22e2376047110f8edbc1a63b165a9b 106 SUPERFAMILY SSF81301 10 105 1.29E-26 T 11-10-2018 TO73_2297 5c22e2376047110f8edbc1a63b165a9b 106 Pfam PF01909 Nucleotidyltransferase domain 23 103 2.6E-15 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TO73_0515 2e3b4361944c5f4fdc981f418cfd2917 108 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 13 104 1.1E-26 T 11-10-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ TO73_0515 2e3b4361944c5f4fdc981f418cfd2917 108 Pfam PF08770 Sulphur oxidation protein SoxZ 14 103 7.5E-25 T 11-10-2018 IPR014880 Sulphur oxidation protein SoxZ TO73_0515 2e3b4361944c5f4fdc981f418cfd2917 108 SUPERFAMILY SSF81296 10 106 6.16E-25 T 11-10-2018 IPR014756 Immunoglobulin E-set TO73_0515 2e3b4361944c5f4fdc981f418cfd2917 108 Gene3D G3DSA:2.60.40.10 2 108 2.6E-35 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0568 141c804b9a07fcbd807b58a5a003a8de 133 Pfam PF02566 OsmC-like protein 28 123 1.6E-18 T 11-10-2018 IPR003718 OsmC/Ohr family TO73_0568 141c804b9a07fcbd807b58a5a003a8de 133 SUPERFAMILY SSF82784 7 127 1.05E-34 T 11-10-2018 IPR036102 OsmC/Ohr superfamily TO73_0568 141c804b9a07fcbd807b58a5a003a8de 133 Gene3D G3DSA:3.30.300.20 5 128 2.4E-32 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_1075 7f67796ad9a735867420562690becfae 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 221 398 4.6E-26 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1075 7f67796ad9a735867420562690becfae 424 Gene3D G3DSA:1.10.287.40 3 51 4.1E-19 T 11-10-2018 TO73_1075 7f67796ad9a735867420562690becfae 424 Gene3D G3DSA:1.10.287.40 57 104 3.3E-10 T 11-10-2018 TO73_1075 7f67796ad9a735867420562690becfae 424 SUPERFAMILY SSF46589 3 112 4.6E-23 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TO73_1075 7f67796ad9a735867420562690becfae 424 PIRSF PIRSF001529 3 422 3.1E-122 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TO73_1075 7f67796ad9a735867420562690becfae 424 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 1.6E-25 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TO73_1075 7f67796ad9a735867420562690becfae 424 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 1.6E-25 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TO73_1075 7f67796ad9a735867420562690becfae 424 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 1.6E-25 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TO73_1075 7f67796ad9a735867420562690becfae 424 PRINTS PR00981 Seryl-tRNA synthetase signature 273 286 1.6E-25 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TO73_1075 7f67796ad9a735867420562690becfae 424 PRINTS PR00981 Seryl-tRNA synthetase signature 261 273 1.6E-25 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TO73_1075 7f67796ad9a735867420562690becfae 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 3 420 35.928 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TO73_1075 7f67796ad9a735867420562690becfae 424 Gene3D G3DSA:3.30.930.10 106 424 1.0E-109 T 11-10-2018 TO73_1075 7f67796ad9a735867420562690becfae 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 3 104 1.4E-21 T 11-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 TO73_1075 7f67796ad9a735867420562690becfae 424 SUPERFAMILY SSF55681 116 422 3.8E-81 T 11-10-2018 TO73_1075 7f67796ad9a735867420562690becfae 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 3 415 1.4E-117 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 250 408 2.6E-39 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 Gene3D G3DSA:1.10.540.10 1 143 3.6E-46 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 371 390 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 238 6.2E-24 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 Gene3D G3DSA:1.20.140.10 250 415 6.7E-56 T 11-10-2018 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 SUPERFAMILY SSF56645 20 261 6.81E-75 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 Gene3D G3DSA:2.40.110.10 144 249 2.0E-36 T 11-10-2018 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 141 3.3E-28 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 SUPERFAMILY SSF47203 248 416 5.64E-50 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 Gene3D G3DSA:1.20.140.10 442 577 7.0E-44 T 11-10-2018 TO73_1060 29ef5d3a79d267fb44398c05cc33279a 577 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 147 159 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_0536 3a46091aa32e4468ce837f6c218dce01 97 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 90 15.706 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0536 3a46091aa32e4468ce837f6c218dce01 97 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 16 97 2.0E-32 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0536 3a46091aa32e4468ce837f6c218dce01 97 TIGRFAM TIGR00029 S20: ribosomal protein bS20 8 91 2.5E-18 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0536 3a46091aa32e4468ce837f6c218dce01 97 SUPERFAMILY SSF46992 10 91 1.02E-23 T 11-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0536 3a46091aa32e4468ce837f6c218dce01 97 Gene3D G3DSA:1.20.58.110 1 97 2.3E-29 T 11-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0536 3a46091aa32e4468ce837f6c218dce01 97 Pfam PF01649 Ribosomal protein S20 10 88 3.5E-20 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1684 8b5107d5da9672adccb5e1af37efd24a 274 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 231 257 - T 11-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 TO73_1684 8b5107d5da9672adccb5e1af37efd24a 274 Pfam PF01148 Cytidylyltransferase family 7 273 1.8E-57 T 11-10-2018 TO73_2513 23414d54341a9f58333dac460143e6d9 235 Pfam PF11740 Plasmid replication region DNA-binding N-term 39 152 8.7E-7 T 11-10-2018 IPR021104 KfrA, N-terminal DNA-binding domain TO73_2027 a9cc4d51f5efa48484cfc085e743f829 329 Gene3D G3DSA:1.20.970.10 1 66 7.1E-22 T 11-10-2018 TO73_2027 a9cc4d51f5efa48484cfc085e743f829 329 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 2 326 34.54 T 11-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TO73_2027 a9cc4d51f5efa48484cfc085e743f829 329 SUPERFAMILY SSF47648 2 64 1.11E-15 T 11-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_2027 a9cc4d51f5efa48484cfc085e743f829 329 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 325 2.3E-108 T 11-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TO73_2027 a9cc4d51f5efa48484cfc085e743f829 329 Pfam PF02885 Glycosyl transferase family, helical bundle domain 2 63 1.9E-16 T 11-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_2027 a9cc4d51f5efa48484cfc085e743f829 329 Gene3D G3DSA:3.40.1030.10 68 328 4.8E-100 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_2027 a9cc4d51f5efa48484cfc085e743f829 329 Pfam PF00591 Glycosyl transferase family, a/b domain 72 317 1.4E-82 T 11-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_2027 a9cc4d51f5efa48484cfc085e743f829 329 SUPERFAMILY SSF52418 71 325 9.29E-83 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TO73_1176 59bacae5c097c16576189290de9faa68 214 SUPERFAMILY SSF69255 23 113 9.15E-14 T 11-10-2018 TO73_1176 59bacae5c097c16576189290de9faa68 214 Gene3D G3DSA:2.40.50.230 18 118 4.2E-6 T 11-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily TO73_1238 eb743815cc7e94ab1fe2611c2f6ff450 277 SUPERFAMILY SSF53850 32 249 2.69E-29 T 11-10-2018 TO73_1238 eb743815cc7e94ab1fe2611c2f6ff450 277 Gene3D G3DSA:3.40.190.10 46 246 2.5E-38 T 11-10-2018 TO73_1238 eb743815cc7e94ab1fe2611c2f6ff450 277 Gene3D G3DSA:3.40.190.10 115 214 2.5E-38 T 11-10-2018 TO73_1238 eb743815cc7e94ab1fe2611c2f6ff450 277 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 41 265 6.7E-39 T 11-10-2018 TO73_1460 2c781d91dbcdc2a83375adef03a0f191 264 SUPERFAMILY SSF56529 47 257 6.15E-74 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TO73_1460 2c781d91dbcdc2a83375adef03a0f191 264 Gene3D G3DSA:2.30.30.370 1 44 6.0E-30 T 11-10-2018 TO73_1460 2c781d91dbcdc2a83375adef03a0f191 264 Pfam PF10370 Domain of unknown function (DUF2437) 1 44 2.8E-8 T 11-10-2018 IPR018833 Domain of unknown function DUF2437 TO73_1460 2c781d91dbcdc2a83375adef03a0f191 264 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 49 256 1.3E-63 T 11-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TO73_1460 2c781d91dbcdc2a83375adef03a0f191 264 Gene3D G3DSA:3.90.850.10 45 264 2.2E-86 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TO73_2147 b3ad976ed2dc080ac035dc7d066d555c 399 SUPERFAMILY SSF51126 23 285 6.28E-22 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor TO73_2147 b3ad976ed2dc080ac035dc7d066d555c 399 SMART SM00710 130 151 3700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_2147 b3ad976ed2dc080ac035dc7d066d555c 399 SMART SM00710 84 105 2200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_2147 b3ad976ed2dc080ac035dc7d066d555c 399 SMART SM00710 245 266 1100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_2147 b3ad976ed2dc080ac035dc7d066d555c 399 SMART SM00710 175 196 8600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_2147 b3ad976ed2dc080ac035dc7d066d555c 399 SMART SM00710 152 174 360.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_2147 b3ad976ed2dc080ac035dc7d066d555c 399 SMART SM00710 53 83 1400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat TO73_2147 b3ad976ed2dc080ac035dc7d066d555c 399 Gene3D G3DSA:2.160.20.10 77 309 1.0E-14 T 11-10-2018 IPR012334 Pectin lyase fold TO73_2147 b3ad976ed2dc080ac035dc7d066d555c 399 Pfam PF05048 Periplasmic copper-binding protein (NosD) 121 289 1.2E-20 T 11-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TO73_0987 93a7fc9dac885164a850b28f55dbbc21 323 Gene3D G3DSA:1.20.1260.10 14 323 7.0E-122 T 11-10-2018 IPR012347 Ferritin-like TO73_0987 93a7fc9dac885164a850b28f55dbbc21 323 SUPERFAMILY SSF47240 41 283 1.33E-75 T 11-10-2018 IPR009078 Ferritin-like superfamily TO73_0987 93a7fc9dac885164a850b28f55dbbc21 323 Pfam PF05138 Phenylacetic acid catabolic protein 31 305 2.4E-93 T 11-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 TO73_0987 93a7fc9dac885164a850b28f55dbbc21 323 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 21 309 2.4E-153 T 11-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 TO73_2736 205229b78c35a2b1b4b6dd94a8a1bab1 202 Gene3D G3DSA:1.10.260.40 1 66 2.3E-12 T 11-10-2018 TO73_2736 205229b78c35a2b1b4b6dd94a8a1bab1 202 SMART SM00530 3 61 1.2E-9 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TO73_2736 205229b78c35a2b1b4b6dd94a8a1bab1 202 Pfam PF13560 Helix-turn-helix domain 3 59 1.7E-9 T 11-10-2018 TO73_2736 205229b78c35a2b1b4b6dd94a8a1bab1 202 SUPERFAMILY SSF47413 2 65 7.88E-12 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TO73_0081 9193dd9ca6326739627510d0091bfbfd 54 SUPERFAMILY SSF57829 2 53 1.28E-21 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TO73_0081 9193dd9ca6326739627510d0091bfbfd 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 11-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0081 9193dd9ca6326739627510d0091bfbfd 54 Pfam PF00471 Ribosomal protein L33 7 53 1.0E-24 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0081 9193dd9ca6326739627510d0091bfbfd 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 5 53 4.5E-23 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0081 9193dd9ca6326739627510d0091bfbfd 54 Gene3D G3DSA:2.20.28.120 1 54 1.1E-28 T 11-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0081 9193dd9ca6326739627510d0091bfbfd 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 20.244 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1732 a4c094f4b15e43e4e42cb88c2b3924be 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 55 219 8.4E-59 T 11-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TO73_1732 a4c094f4b15e43e4e42cb88c2b3924be 227 SUPERFAMILY SSF75445 131 208 1.44E-21 T 11-10-2018 TO73_1732 a4c094f4b15e43e4e42cb88c2b3924be 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 5 225 30.684 T 11-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TO73_1732 a4c094f4b15e43e4e42cb88c2b3924be 227 Gene3D G3DSA:3.40.50.1360 1 133 2.9E-52 T 11-10-2018 TO73_1732 a4c094f4b15e43e4e42cb88c2b3924be 227 SUPERFAMILY SSF100950 6 179 3.23E-42 T 11-10-2018 IPR037171 NagB/RpiA transferase-like TO73_1732 a4c094f4b15e43e4e42cb88c2b3924be 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 9 222 2.5E-73 T 11-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TO73_1732 a4c094f4b15e43e4e42cb88c2b3924be 227 Gene3D G3DSA:3.30.70.260 134 205 2.0E-25 T 11-10-2018 TO73_1307 8121efa7241179cec56c18c3e877cc3c 244 Pfam PF00588 SpoU rRNA Methylase family 8 160 4.9E-38 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TO73_1307 8121efa7241179cec56c18c3e877cc3c 244 SUPERFAMILY SSF75217 7 186 2.35E-33 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases TO73_1307 8121efa7241179cec56c18c3e877cc3c 244 PIRSF PIRSF004808 3 244 3.1E-75 T 11-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TO73_1307 8121efa7241179cec56c18c3e877cc3c 244 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 6 237 9.6E-64 T 11-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TO73_1307 8121efa7241179cec56c18c3e877cc3c 244 Gene3D G3DSA:1.10.8.590 171 243 6.4E-16 T 11-10-2018 TO73_1307 8121efa7241179cec56c18c3e877cc3c 244 Gene3D G3DSA:3.40.1280.10 4 170 2.7E-55 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TO73_0227 e321dac2c7b2adc1fefbd9622b22755e 299 Gene3D G3DSA:2.70.70.10 139 295 1.3E-49 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_0227 e321dac2c7b2adc1fefbd9622b22755e 299 SUPERFAMILY SSF51261 156 292 1.26E-55 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_0227 e321dac2c7b2adc1fefbd9622b22755e 299 Pfam PF01551 Peptidase family M23 194 288 3.1E-34 T 11-10-2018 IPR016047 Peptidase M23 TO73_1010 d728481245a0fbd81b5844288b60f89d 359 SUPERFAMILY SSF159672 10 239 1.14E-55 T 11-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 TO73_1010 d728481245a0fbd81b5844288b60f89d 359 Gene3D G3DSA:3.30.420.180 223 353 5.9E-41 T 11-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 TO73_1010 d728481245a0fbd81b5844288b60f89d 359 Pfam PF01890 Cobalamin synthesis G C-terminus 232 346 5.1E-33 T 11-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 TO73_1010 d728481245a0fbd81b5844288b60f89d 359 Pfam PF11760 Cobalamin synthesis G N-terminal 60 140 4.7E-30 T 11-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 TO73_1010 d728481245a0fbd81b5844288b60f89d 359 SUPERFAMILY SSF159664 225 350 4.19E-36 T 11-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 TO73_1010 d728481245a0fbd81b5844288b60f89d 359 Gene3D G3DSA:3.40.50.11220 11 135 2.2E-26 T 11-10-2018 TO73_1010 d728481245a0fbd81b5844288b60f89d 359 Pfam PF11761 Cobalamin biosynthesis central region 145 229 9.9E-9 T 11-10-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 TO73_1041 df1254900e1c3f59b7b13c82447ab426 106 SMART SM00448 1 99 8.9E-23 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1041 df1254900e1c3f59b7b13c82447ab426 106 Pfam PF00072 Response regulator receiver domain 2 99 1.2E-20 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1041 df1254900e1c3f59b7b13c82447ab426 106 Gene3D G3DSA:3.40.50.2300 1 106 2.7E-30 T 11-10-2018 TO73_1041 df1254900e1c3f59b7b13c82447ab426 106 SUPERFAMILY SSF52172 2 104 1.99E-29 T 11-10-2018 IPR011006 CheY-like superfamily TO73_0362 27ea4b0eef6f7d320a0b8858b47568f0 276 Pfam PF00892 EamA-like transporter family 6 130 3.9E-10 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_0362 27ea4b0eef6f7d320a0b8858b47568f0 276 Pfam PF00892 EamA-like transporter family 141 268 3.3E-21 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_0362 27ea4b0eef6f7d320a0b8858b47568f0 276 SUPERFAMILY SSF103481 176 274 1.31E-16 T 11-10-2018 TO73_0362 27ea4b0eef6f7d320a0b8858b47568f0 276 SUPERFAMILY SSF103481 40 134 1.57E-5 T 11-10-2018 TO73_0062 e8fb3f7f6f5d850a167edc77daca8d2b 157 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 151 2.6E-50 T 11-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0062 e8fb3f7f6f5d850a167edc77daca8d2b 157 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 155 30.048 T 11-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0062 e8fb3f7f6f5d850a167edc77daca8d2b 157 Gene3D G3DSA:3.40.50.960 4 156 2.2E-54 T 11-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0062 e8fb3f7f6f5d850a167edc77daca8d2b 157 SUPERFAMILY SSF52121 6 155 2.62E-56 T 11-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0062 e8fb3f7f6f5d850a167edc77daca8d2b 157 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 15 152 1.8E-50 T 11-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0092 8f40f24f99a4f361113899cff8711564 68 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 6 60 8.9E-19 T 11-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TO73_0092 8f40f24f99a4f361113899cff8711564 68 SUPERFAMILY SSF54786 3 67 3.65E-19 T 11-10-2018 TO73_0092 8f40f24f99a4f361113899cff8711564 68 Gene3D G3DSA:3.30.920.30 1 68 3.2E-29 T 11-10-2018 IPR038570 HicA superfamily TO73_1539 6a8310a6b88cf6e7cc5fa0ce35cedd10 144 Gene3D G3DSA:3.60.90.10 5 133 4.0E-36 T 11-10-2018 TO73_1539 6a8310a6b88cf6e7cc5fa0ce35cedd10 144 SUPERFAMILY SSF56276 6 119 2.9E-27 T 11-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TO73_1539 6a8310a6b88cf6e7cc5fa0ce35cedd10 144 Pfam PF02675 S-adenosylmethionine decarboxylase 9 118 3.1E-29 T 11-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TO73_1539 6a8310a6b88cf6e7cc5fa0ce35cedd10 144 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 118 5.1E-24 T 11-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TO73_0651 e4938f84ae91ab5ab096c6d25212404a 272 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 24 266 5.0E-66 T 11-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TO73_0651 e4938f84ae91ab5ab096c6d25212404a 272 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 17 265 2.9E-54 T 11-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 TO73_0651 e4938f84ae91ab5ab096c6d25212404a 272 SUPERFAMILY SSF53335 3 268 2.11E-54 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_0651 e4938f84ae91ab5ab096c6d25212404a 272 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 175 181 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TO73_0651 e4938f84ae91ab5ab096c6d25212404a 272 Gene3D G3DSA:1.10.8.10 2 81 1.3E-16 T 11-10-2018 TO73_0651 e4938f84ae91ab5ab096c6d25212404a 272 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 270 37.43 T 11-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TO73_0651 e4938f84ae91ab5ab096c6d25212404a 272 Gene3D G3DSA:3.40.50.150 82 271 7.8E-49 T 11-10-2018 TO73_0651 e4938f84ae91ab5ab096c6d25212404a 272 Pfam PF05175 Methyltransferase small domain 104 182 2.2E-14 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 SUPERFAMILY SSF54849 136 201 2.29E-23 T 11-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 Gene3D G3DSA:3.50.7.10 190 370 2.1E-234 T 11-10-2018 IPR027409 GroEL-like apical domain superfamily TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 528 1.1E-255 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 SUPERFAMILY SSF52029 182 374 6.73E-83 T 11-10-2018 IPR027409 GroEL-like apical domain superfamily TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 Gene3D G3DSA:3.30.260.10 135 408 2.1E-234 T 11-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 Gene3D G3DSA:1.10.560.10 7 522 2.1E-234 T 11-10-2018 IPR027413 GroEL-like equatorial domain superfamily TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 SUPERFAMILY SSF48592 6 522 1.37E-81 T 11-10-2018 IPR027413 GroEL-like equatorial domain superfamily TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 11-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 2.9E-104 T 11-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 Hamap MF_00600 60 kDa chaperonin [groL]. 1 541 42.023 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 PRINTS PR00298 60kDa chaperonin signature 26 52 3.2E-72 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 PRINTS PR00298 60kDa chaperonin signature 266 289 3.2E-72 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 PRINTS PR00298 60kDa chaperonin signature 396 417 3.2E-72 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 PRINTS PR00298 60kDa chaperonin signature 82 109 3.2E-72 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TO73_0029 b234b4d2a3b47b48a749d03a73a2b681 543 PRINTS PR00298 60kDa chaperonin signature 348 373 3.2E-72 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TO73_2305 8403540355b4907075066ac4f9579e05 522 SMART SM00471 358 492 7.8E-10 T 11-10-2018 IPR003607 HD/PDEase domain TO73_2305 8403540355b4907075066ac4f9579e05 522 SMART SM00065 193 341 2.0E-7 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_2305 8403540355b4907075066ac4f9579e05 522 SMART SM00065 26 172 6.4E-23 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_2305 8403540355b4907075066ac4f9579e05 522 Gene3D G3DSA:1.10.3210.10 342 522 4.9E-68 T 11-10-2018 TO73_2305 8403540355b4907075066ac4f9579e05 522 SUPERFAMILY SSF55781 8 183 1.44E-25 T 11-10-2018 TO73_2305 8403540355b4907075066ac4f9579e05 522 Pfam PF13487 HD domain 413 473 6.1E-21 T 11-10-2018 TO73_2305 8403540355b4907075066ac4f9579e05 522 Gene3D G3DSA:3.30.450.40 173 341 1.4E-19 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_2305 8403540355b4907075066ac4f9579e05 522 Gene3D G3DSA:3.30.450.40 5 172 2.4E-27 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_2305 8403540355b4907075066ac4f9579e05 522 SUPERFAMILY SSF109604 347 521 1.83E-38 T 11-10-2018 TO73_2305 8403540355b4907075066ac4f9579e05 522 Pfam PF13185 GAF domain 26 162 2.5E-13 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_2305 8403540355b4907075066ac4f9579e05 522 Pfam PF13185 GAF domain 197 327 3.7E-12 T 11-10-2018 IPR003018 GAF domain GO:0005515 TO73_2305 8403540355b4907075066ac4f9579e05 522 SUPERFAMILY SSF55781 158 333 2.4E-19 T 11-10-2018 TO73_2305 8403540355b4907075066ac4f9579e05 522 TIGRFAM TIGR00277 HDIG: HDIG domain 364 450 1.3E-7 T 11-10-2018 IPR006675 HDIG domain TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 Gene3D G3DSA:3.40.50.170 89 285 5.6E-78 T 11-10-2018 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 Gene3D G3DSA:3.30.70.260 1 88 5.3E-32 T 11-10-2018 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 112 139 7.2E-61 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 90 112 7.2E-61 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 39 51 7.2E-61 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 258 283 7.2E-61 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 7.2E-61 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 236 258 7.2E-61 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 284 9.7E-122 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 SUPERFAMILY SSF55021 4 88 5.5E-17 T 11-10-2018 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 Pfam PF00551 Formyl transferase 89 266 2.4E-40 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 PIRSF PIRSF036480 1 285 2.9E-114 T 11-10-2018 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 284 47.86 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 SUPERFAMILY SSF53328 89 284 4.06E-61 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TO73_0611 bdd505ff4b1420a1ab1d77a46190b085 285 Pfam PF01842 ACT domain 5 67 1.4E-12 T 11-10-2018 IPR002912 ACT domain TO73_0427 fe15e01d7cd227850bfa5ace328d8217 494 SUPERFAMILY SSF51445 13 414 1.42E-104 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily TO73_0427 fe15e01d7cd227850bfa5ace328d8217 494 Pfam PF00128 Alpha amylase, catalytic domain 66 379 2.1E-66 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TO73_0427 fe15e01d7cd227850bfa5ace328d8217 494 Gene3D G3DSA:3.20.20.80 20 409 5.6E-165 T 11-10-2018 TO73_0427 fe15e01d7cd227850bfa5ace328d8217 494 Gene3D G3DSA:2.60.40.1180 410 494 3.6E-52 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta TO73_0427 fe15e01d7cd227850bfa5ace328d8217 494 SMART SM00642 30 407 1.6E-105 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TO73_0025 aa68b915bee331cda53959ecfaefc932 106 Pfam PF04930 FUN14 family 13 103 2.2E-25 T 11-10-2018 IPR007014 FUN14 TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 Pfam PF02817 e3 binding domain 149 184 2.9E-14 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 Gene3D G3DSA:4.10.320.10 138 188 1.9E-16 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 SUPERFAMILY SSF52777 198 439 4.89E-85 T 11-10-2018 TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 Gene3D G3DSA:2.40.50.100 1 79 7.2E-22 T 11-10-2018 TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 213 440 9.8E-85 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 Gene3D G3DSA:3.30.559.10 199 442 1.6E-91 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 Pfam PF00364 Biotin-requiring enzyme 2 73 4.7E-19 T 11-10-2018 IPR000089 Biotin/lipoyl attachment TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 SUPERFAMILY SSF47005 144 187 8.37E-12 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TO73_2200 91eb7b34fc3c241373fbdc8284227af8 443 SUPERFAMILY SSF51230 2 79 5.1E-21 T 11-10-2018 IPR011053 Single hybrid motif TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 SUPERFAMILY SSF52540 3 194 7.09E-52 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 SUPERFAMILY SSF50447 147 291 7.46E-26 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 Gene3D G3DSA:3.30.70.240 380 466 2.0E-112 T 11-10-2018 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 SMART SM00838 384 468 0.0043 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 40 55 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 Pfam PF00679 Elongation factor G C-terminus 384 459 6.5E-17 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 PRINTS PR00315 GTP-binding elongation factor signature 5 18 2.7E-15 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 PRINTS PR00315 GTP-binding elongation factor signature 83 94 2.7E-15 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 PRINTS PR00315 GTP-binding elongation factor signature 47 55 2.7E-15 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 PRINTS PR00315 GTP-binding elongation factor signature 119 128 2.7E-15 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 PRINTS PR00315 GTP-binding elongation factor signature 67 77 2.7E-15 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 Pfam PF03144 Elongation factor Tu domain 2 212 280 8.3E-10 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 Gene3D G3DSA:2.40.50.250 467 583 2.0E-112 T 11-10-2018 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 134 1.9E-23 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 Gene3D G3DSA:3.30.70.870 298 574 2.0E-112 T 11-10-2018 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 Pfam PF00009 Elongation factor Tu GTP binding domain 2 189 3.8E-50 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 Gene3D G3DSA:3.40.50.300 1 192 1.5E-62 T 11-10-2018 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 SUPERFAMILY SSF54980 385 497 1.01E-23 T 11-10-2018 IPR035647 EF-G domain III/V-like TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 SUPERFAMILY SSF54980 294 378 3.31E-11 T 11-10-2018 IPR035647 EF-G domain III/V-like TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 Gene3D G3DSA:2.40.30.10 194 291 5.8E-30 T 11-10-2018 TO73_2292 34e30bc9d6d7d064f5828d7202277e4a 587 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 583 1.6E-252 T 11-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 TO73_1964 b360cbd91ee45f8a671eefc89ab5ecc2 223 SUPERFAMILY SSF52172 3 166 4.97E-35 T 11-10-2018 IPR011006 CheY-like superfamily TO73_1964 b360cbd91ee45f8a671eefc89ab5ecc2 223 Pfam PF00072 Response regulator receiver domain 4 112 8.0E-24 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1964 b360cbd91ee45f8a671eefc89ab5ecc2 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 3.2E-28 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_1964 b360cbd91ee45f8a671eefc89ab5ecc2 223 Gene3D G3DSA:3.40.50.2300 1 125 6.8E-33 T 11-10-2018 TO73_1964 b360cbd91ee45f8a671eefc89ab5ecc2 223 SMART SM00862 143 219 3.9E-30 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_1964 b360cbd91ee45f8a671eefc89ab5ecc2 223 SMART SM00448 2 112 4.9E-38 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1964 b360cbd91ee45f8a671eefc89ab5ecc2 223 Gene3D G3DSA:1.10.10.10 126 223 3.5E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2339 bfd1408d740eb3066d7b4b7ceb33ba1e 305 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 119 1.0E-26 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TO73_2339 bfd1408d740eb3066d7b4b7ceb33ba1e 305 Gene3D G3DSA:2.60.200.40 123 274 7.9E-36 T 11-10-2018 TO73_2339 bfd1408d740eb3066d7b4b7ceb33ba1e 305 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 5 270 1.0E-35 T 11-10-2018 IPR005218 Diacylglycerol/lipid kinase TO73_2339 bfd1408d740eb3066d7b4b7ceb33ba1e 305 SUPERFAMILY SSF111331 4 287 4.14E-69 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TO73_2339 bfd1408d740eb3066d7b4b7ceb33ba1e 305 Gene3D G3DSA:3.40.50.10330 2 122 1.6E-29 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TO73_2339 bfd1408d740eb3066d7b4b7ceb33ba1e 305 SMART SM00046 2 119 5.5E-9 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TO73_0132 8226636c0841808e45c58c5a22748314 219 SUPERFAMILY SSF55681 3 207 1.16E-63 T 11-10-2018 TO73_0132 8226636c0841808e45c58c5a22748314 219 Hamap MF_00013 Octanoyltransferase [lipB]. 2 208 33.833 T 11-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TO73_0132 8226636c0841808e45c58c5a22748314 219 Pfam PF03099 Biotin/lipoate A/B protein ligase family 65 160 7.2E-6 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TO73_0132 8226636c0841808e45c58c5a22748314 219 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 79 123 5.0E-16 T 11-10-2018 TO73_0132 8226636c0841808e45c58c5a22748314 219 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 75 90 - T 11-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TO73_0132 8226636c0841808e45c58c5a22748314 219 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 35 206 2.2E-45 T 11-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TO73_0132 8226636c0841808e45c58c5a22748314 219 PIRSF PIRSF016262 3 217 7.5E-57 T 11-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TO73_0132 8226636c0841808e45c58c5a22748314 219 Gene3D G3DSA:3.30.930.10 2 206 8.7E-80 T 11-10-2018 TO73_0498 a77347b9c331330b2e3085ebeaf5d3f8 214 Gene3D G3DSA:1.10.10.10 116 212 1.3E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0498 a77347b9c331330b2e3085ebeaf5d3f8 214 SUPERFAMILY SSF46894 123 212 2.38E-18 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TO73_0498 a77347b9c331330b2e3085ebeaf5d3f8 214 Pfam PF00486 Transcriptional regulatory protein, C terminal 142 211 2.0E-18 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_0498 a77347b9c331330b2e3085ebeaf5d3f8 214 SMART SM00448 1 109 2.1E-35 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_0498 a77347b9c331330b2e3085ebeaf5d3f8 214 SMART SM00862 141 211 2.6E-23 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TO73_0498 a77347b9c331330b2e3085ebeaf5d3f8 214 Pfam PF00072 Response regulator receiver domain 3 109 6.5E-22 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_0498 a77347b9c331330b2e3085ebeaf5d3f8 214 SUPERFAMILY SSF52172 1 153 2.13E-35 T 11-10-2018 IPR011006 CheY-like superfamily TO73_0498 a77347b9c331330b2e3085ebeaf5d3f8 214 Gene3D G3DSA:3.40.50.2300 1 115 3.6E-33 T 11-10-2018 TO73_1995 e69f1593020778a5ee73deddf06341d4 318 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 19 315 1.3E-126 T 11-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 TO73_1995 e69f1593020778a5ee73deddf06341d4 318 Gene3D G3DSA:3.20.10.10 141 304 3.4E-53 T 11-10-2018 TO73_1995 e69f1593020778a5ee73deddf06341d4 318 Pfam PF01063 Amino-transferase class IV 45 275 2.9E-50 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TO73_1995 e69f1593020778a5ee73deddf06341d4 318 Gene3D G3DSA:3.30.470.10 15 140 5.6E-46 T 11-10-2018 TO73_1995 e69f1593020778a5ee73deddf06341d4 318 SUPERFAMILY SSF56752 16 316 7.72E-101 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TO73_2319 198ae023d49f70c6843015bfb39a6814 237 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 104 217 2.7E-35 T 11-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal TO73_2319 198ae023d49f70c6843015bfb39a6814 237 PIRSF PIRSF004793 1 237 5.4E-78 T 11-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 TO73_2319 198ae023d49f70c6843015bfb39a6814 237 Hamap MF_01499 Diadenylate cyclase [dacA]. 2 236 31.21 T 11-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 TO73_2319 198ae023d49f70c6843015bfb39a6814 237 Gene3D G3DSA:3.40.1700.10 90 237 9.1E-47 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TO73_2319 198ae023d49f70c6843015bfb39a6814 237 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 5 232 5.5E-65 T 11-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 TO73_2319 198ae023d49f70c6843015bfb39a6814 237 SUPERFAMILY SSF143597 33 219 2.75E-54 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TO73_0166 3c62f088ae20fbde2f1665c29dfa8ff1 310 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 41 54 - T 11-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TO73_0166 3c62f088ae20fbde2f1665c29dfa8ff1 310 Gene3D G3DSA:3.40.50.1100 49 142 1.1E-116 T 11-10-2018 TO73_0166 3c62f088ae20fbde2f1665c29dfa8ff1 310 Gene3D G3DSA:3.40.50.1100 15 305 1.1E-116 T 11-10-2018 TO73_0166 3c62f088ae20fbde2f1665c29dfa8ff1 310 SUPERFAMILY SSF53686 4 308 2.23E-85 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TO73_0166 3c62f088ae20fbde2f1665c29dfa8ff1 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 14 302 1.8E-73 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 SUPERFAMILY SSF52540 3 306 4.64E-80 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 1 368 44.022 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 88 1.0E-33 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 1.0E-33 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 90 108 1.0E-33 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 1.0E-33 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 SUPERFAMILY SSF81271 284 364 2.09E-33 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 Gene3D G3DSA:3.10.20.30 47 362 2.8E-146 T 11-10-2018 IPR012675 Beta-grasp domain superfamily TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 Pfam PF01926 50S ribosome-binding GTPase 4 118 4.6E-23 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 Gene3D G3DSA:3.40.50.300 4 285 2.8E-146 T 11-10-2018 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 PIRSF PIRSF006641 1 368 1.2E-142 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 Gene3D G3DSA:1.10.150.300 126 204 2.8E-146 T 11-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 Pfam PF06071 Protein of unknown function (DUF933) 284 366 8.3E-35 T 11-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 TO73_1312 201ea4d10f9e62f4cfe6c926245e2ed1 368 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 2 367 2.9E-129 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TO73_1561 04db4f8b4489d0e355fe077e3da271e4 147 Gene3D G3DSA:3.30.460.10 13 108 2.5E-8 T 11-10-2018 TO73_1561 04db4f8b4489d0e355fe077e3da271e4 147 Pfam PF01909 Nucleotidyltransferase domain 35 65 7.0E-7 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TO73_1561 04db4f8b4489d0e355fe077e3da271e4 147 SUPERFAMILY SSF81301 13 115 3.04E-13 T 11-10-2018 TO73_1920 2a198ddc1e4d0c516b4c80a81cff2f03 79 Pfam PF13591 MerR HTH family regulatory protein 11 78 4.2E-12 T 11-10-2018 TO73_1920 2a198ddc1e4d0c516b4c80a81cff2f03 79 SUPERFAMILY SSF46955 11 54 5.95E-6 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily TO73_1920 2a198ddc1e4d0c516b4c80a81cff2f03 79 Gene3D G3DSA:1.10.1660.10 7 79 8.3E-15 T 11-10-2018 TO73_0749 bf85b1edf76631095717129d0a943dd6 165 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 119 136 - T 11-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TO73_0749 bf85b1edf76631095717129d0a943dd6 165 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 4 163 2.6E-48 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TO73_0749 bf85b1edf76631095717129d0a943dd6 165 Pfam PF00364 Biotin-requiring enzyme 89 162 6.6E-25 T 11-10-2018 IPR000089 Biotin/lipoyl attachment TO73_0749 bf85b1edf76631095717129d0a943dd6 165 SUPERFAMILY SSF51230 87 162 5.1E-26 T 11-10-2018 IPR011053 Single hybrid motif TO73_0749 bf85b1edf76631095717129d0a943dd6 165 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 124 137 1.3E-18 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TO73_0749 bf85b1edf76631095717129d0a943dd6 165 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 109 123 1.3E-18 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TO73_0749 bf85b1edf76631095717129d0a943dd6 165 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 92 105 1.3E-18 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TO73_0749 bf85b1edf76631095717129d0a943dd6 165 Gene3D G3DSA:2.40.50.100 87 162 1.9E-33 T 11-10-2018 TO73_1615 a53304559852de6a5e06fc5540b40f13 494 Pfam PF03023 MviN-like protein 29 433 2.1E-67 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TO73_1615 a53304559852de6a5e06fc5540b40f13 494 PRINTS PR01806 Virulence factor MviN signature 30 49 5.7E-25 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TO73_1615 a53304559852de6a5e06fc5540b40f13 494 PRINTS PR01806 Virulence factor MviN signature 340 359 5.7E-25 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TO73_1615 a53304559852de6a5e06fc5540b40f13 494 PRINTS PR01806 Virulence factor MviN signature 49 65 5.7E-25 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TO73_1615 a53304559852de6a5e06fc5540b40f13 494 PRINTS PR01806 Virulence factor MviN signature 391 408 5.7E-25 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TO73_1615 a53304559852de6a5e06fc5540b40f13 494 PRINTS PR01806 Virulence factor MviN signature 128 152 5.7E-25 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TO73_1615 a53304559852de6a5e06fc5540b40f13 494 PRINTS PR01806 Virulence factor MviN signature 152 173 5.7E-25 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TO73_1615 a53304559852de6a5e06fc5540b40f13 494 PRINTS PR01806 Virulence factor MviN signature 245 271 5.7E-25 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TO73_1615 a53304559852de6a5e06fc5540b40f13 494 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 479 2.0E-73 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TO73_1574 03488fed4bf8a4d12fff99ca10101cd6 247 Pfam PF00149 Calcineurin-like phosphoesterase 1 193 4.4E-8 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TO73_1574 03488fed4bf8a4d12fff99ca10101cd6 247 Gene3D G3DSA:3.60.21.10 1 222 1.7E-19 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like TO73_1574 03488fed4bf8a4d12fff99ca10101cd6 247 SUPERFAMILY SSF56300 1 216 2.06E-19 T 11-10-2018 TO73_1181 0d6d903fea05e6544184a8d028dc5300 173 Gene3D G3DSA:3.40.390.50 44 127 6.6E-8 T 11-10-2018 TO73_1181 0d6d903fea05e6544184a8d028dc5300 173 Pfam PF06114 IrrE N-terminal-like domain 28 163 2.8E-22 T 11-10-2018 IPR010359 IrrE N-terminal-like domain TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 Pfam PF00994 Probable molybdopterin binding domain 182 316 2.2E-22 T 11-10-2018 IPR001453 MoaB/Mog domain TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 Pfam PF03454 MoeA C-terminal region (domain IV) 331 400 1.6E-16 T 11-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 Gene3D G3DSA:2.170.190.11 48 143 9.5E-104 T 11-10-2018 TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 179 308 1.0E-26 T 11-10-2018 IPR001453 MoaB/Mog domain TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 SMART SM00852 182 318 5.4E-40 T 11-10-2018 IPR001453 MoaB/Mog domain TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 SUPERFAMILY SSF63867 329 400 1.09E-14 T 11-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 SUPERFAMILY SSF63882 5 178 8.37E-49 T 11-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 169 7.3E-37 T 11-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 SUPERFAMILY SSF53218 179 323 7.2E-40 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 Gene3D G3DSA:3.90.105.10 25 176 9.5E-104 T 11-10-2018 TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 Gene3D G3DSA:3.40.980.10 177 316 9.5E-104 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily TO73_1898 2a93089418a7e36ed471ee07a53eaeb1 404 Gene3D G3DSA:2.40.340.10 329 397 4.7E-15 T 11-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 SUPERFAMILY SSF52540 375 537 4.13E-32 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 Gene3D G3DSA:3.40.50.300 374 539 1.2E-29 T 11-10-2018 TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 Pfam PF13167 GTP-binding GTPase N-terminal 202 289 1.8E-26 T 11-10-2018 IPR025121 GTPase HflX, N-terminal TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 Hamap MF_00900 GTPase HflX [hflX]. 204 540 41.327 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 Pfam PF16360 GTP-binding GTPase Middle Region 291 369 2.2E-28 T 11-10-2018 IPR032305 GTP-binding protein, middle domain TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 186 534 3.5E-123 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 Pfam PF01926 50S ribosome-binding GTPase 377 478 1.4E-13 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 Gene3D G3DSA:3.40.50.11060 197 315 7.0E-35 T 11-10-2018 TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 377 397 7.5E-8 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1401 20f8a5bb3aa4ca5e6bd57a1f1f4a35b8 548 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 444 462 7.5E-8 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0031 a91d5e5c439e495fa858a787e75df0d7 262 SMART SM00967 30 98 1.7E-6 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TO73_0031 a91d5e5c439e495fa858a787e75df0d7 262 Pfam PF00588 SpoU rRNA Methylase family 109 247 1.1E-31 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TO73_0031 a91d5e5c439e495fa858a787e75df0d7 262 Gene3D G3DSA:3.40.1280.10 104 257 5.2E-55 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TO73_0031 a91d5e5c439e495fa858a787e75df0d7 262 SUPERFAMILY SSF55315 2 96 7.77E-22 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like TO73_0031 a91d5e5c439e495fa858a787e75df0d7 262 SUPERFAMILY SSF75217 102 253 4.77E-41 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases TO73_0031 a91d5e5c439e495fa858a787e75df0d7 262 Gene3D G3DSA:3.30.1330.30 1 96 4.0E-29 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like TO73_1614 fd06fe581a1e8091c9d31c2487ef8f4a 793 Gene3D G3DSA:3.20.20.80 142 260 4.9E-6 T 11-10-2018 TO73_1614 fd06fe581a1e8091c9d31c2487ef8f4a 793 Gene3D G3DSA:3.20.20.80 347 558 1.4E-5 T 11-10-2018 TO73_1614 fd06fe581a1e8091c9d31c2487ef8f4a 793 Gene3D G3DSA:1.25.40.10 8 125 3.0E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1614 fd06fe581a1e8091c9d31c2487ef8f4a 793 SUPERFAMILY SSF48452 18 116 4.61E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1614 fd06fe581a1e8091c9d31c2487ef8f4a 793 SUPERFAMILY SSF51445 139 526 1.19E-15 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily TO73_0635 7a9db5bd94188217ddedf292484435b6 271 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 114 134 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TO73_0635 7a9db5bd94188217ddedf292484435b6 271 Gene3D G3DSA:3.90.226.10 3 213 4.6E-76 T 11-10-2018 TO73_0635 7a9db5bd94188217ddedf292484435b6 271 SUPERFAMILY SSF52096 10 270 3.58E-95 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_0635 7a9db5bd94188217ddedf292484435b6 271 Gene3D G3DSA:1.10.12.10 214 271 2.7E-21 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TO73_0635 7a9db5bd94188217ddedf292484435b6 271 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 270 6.1E-71 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TO73_0664 a909c13054be6e8865a846af3d77f3fb 322 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 319 63.811 T 11-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TO73_0664 a909c13054be6e8865a846af3d77f3fb 322 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 230 319 2.6E-39 T 11-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TO73_0664 a909c13054be6e8865a846af3d77f3fb 322 Gene3D G3DSA:3.40.47.10 1 171 2.6E-69 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0664 a909c13054be6e8865a846af3d77f3fb 322 Gene3D G3DSA:3.40.47.10 172 322 2.1E-57 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0664 a909c13054be6e8865a846af3d77f3fb 322 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 104 182 2.3E-25 T 11-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TO73_0664 a909c13054be6e8865a846af3d77f3fb 322 SUPERFAMILY SSF53901 3 319 2.62E-70 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0664 a909c13054be6e8865a846af3d77f3fb 322 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 319 7.4E-111 T 11-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 Pfam PF00027 Cyclic nucleotide-binding domain 28 107 2.6E-16 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 SUPERFAMILY SSF51206 5 124 3.4E-21 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 Gene3D G3DSA:2.60.120.10 4 126 2.2E-20 T 11-10-2018 IPR014710 RmlC-like jelly roll fold TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 SUPERFAMILY SSF54631 136 252 2.91E-28 T 11-10-2018 TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 SMART SM00116 207 254 9.5E-9 T 11-10-2018 IPR000644 CBS domain TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 SMART SM00116 145 190 5.2E-6 T 11-10-2018 IPR000644 CBS domain TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 439 577 2.8E-42 T 11-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 Pfam PF00571 CBS domain 200 250 4.2E-9 T 11-10-2018 IPR000644 CBS domain TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 Pfam PF00571 CBS domain 138 189 3.0E-10 T 11-10-2018 IPR000644 CBS domain TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 Pfam PF03445 Putative nucleotidyltransferase DUF294 273 404 2.4E-43 T 11-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 SMART SM00100 8 121 1.3E-10 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain TO73_1452 814fe36a81d48cd7d1a3fc85fdea1bf3 580 Gene3D G3DSA:3.10.580.10 132 256 2.3E-32 T 11-10-2018 TO73_0948 9756a161ffebd244dcc321caed84d050 243 Pfam PF01975 Survival protein SurE 4 179 2.1E-45 T 11-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TO73_0948 9756a161ffebd244dcc321caed84d050 243 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 228 8.0E-50 T 11-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TO73_0948 9756a161ffebd244dcc321caed84d050 243 SUPERFAMILY SSF64167 3 237 2.35E-68 T 11-10-2018 TO73_0948 9756a161ffebd244dcc321caed84d050 243 Gene3D G3DSA:3.40.1210.10 2 239 5.2E-87 T 11-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TO73_0948 9756a161ffebd244dcc321caed84d050 243 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 242 30.746 T 11-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TO73_0586 275e2e48208eaa38704fb0e8e62f6e0f 149 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 149 64.63 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TO73_0586 275e2e48208eaa38704fb0e8e62f6e0f 149 SUPERFAMILY SSF52304 6 146 2.49E-57 T 11-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TO73_0586 275e2e48208eaa38704fb0e8e62f6e0f 149 Pfam PF01220 Dehydroquinase class II 6 142 2.3E-54 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TO73_0586 275e2e48208eaa38704fb0e8e62f6e0f 149 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 5 145 1.4E-58 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TO73_0586 275e2e48208eaa38704fb0e8e62f6e0f 149 Gene3D G3DSA:3.40.50.9100 5 149 1.4E-63 T 11-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TO73_0586 275e2e48208eaa38704fb0e8e62f6e0f 149 ProSitePatterns PS01029 Dehydroquinase class II signature. 9 26 - T 11-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TO73_0586 275e2e48208eaa38704fb0e8e62f6e0f 149 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 19 136 9.0E-48 T 11-10-2018 TO73_0586 275e2e48208eaa38704fb0e8e62f6e0f 149 PIRSF PIRSF001399 3 148 6.0E-59 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TO73_0317 7302b1e016c35723b7e5644d58931316 197 Gene3D G3DSA:3.90.1140.10 1 197 3.0E-60 T 11-10-2018 TO73_0317 7302b1e016c35723b7e5644d58931316 197 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 178 23.361 T 11-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TO73_0317 7302b1e016c35723b7e5644d58931316 197 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 178 3.8E-33 T 11-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TO73_0317 7302b1e016c35723b7e5644d58931316 197 Pfam PF02834 LigT like Phosphoesterase 7 89 2.0E-14 T 11-10-2018 IPR014051 Phosphoesterase, HXTX TO73_0317 7302b1e016c35723b7e5644d58931316 197 Pfam PF02834 LigT like Phosphoesterase 103 170 1.3E-8 T 11-10-2018 IPR014051 Phosphoesterase, HXTX TO73_0317 7302b1e016c35723b7e5644d58931316 197 SUPERFAMILY SSF55144 1 180 2.96E-46 T 11-10-2018 IPR009097 Cyclic phosphodiesterase TO73_2238 f1c3ec55eb64c6673cf87b06ca385539 635 Gene3D G3DSA:1.10.357.140 365 518 1.1E-21 T 11-10-2018 TO73_2238 f1c3ec55eb64c6673cf87b06ca385539 635 Pfam PF02628 Cytochrome oxidase assembly protein 38 321 9.2E-30 T 11-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 TO73_2238 f1c3ec55eb64c6673cf87b06ca385539 635 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 355 632 9.8E-100 T 11-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TO73_2238 f1c3ec55eb64c6673cf87b06ca385539 635 Pfam PF01040 UbiA prenyltransferase family 369 615 2.6E-63 T 11-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TO73_2238 f1c3ec55eb64c6673cf87b06ca385539 635 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 353 634 19.741 T 11-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TO73_0119 8ac958c42258deb09017e9bdb0b02eca 376 Pfam PF07690 Major Facilitator Superfamily 10 221 1.2E-25 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_0119 8ac958c42258deb09017e9bdb0b02eca 376 SUPERFAMILY SSF103473 3 375 2.49E-55 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_0119 8ac958c42258deb09017e9bdb0b02eca 376 Gene3D G3DSA:1.20.1250.20 1 376 1.9E-51 T 11-10-2018 TO73_0422 56d6082cc676bd917a7d675c48e81191 272 Pfam PF02621 Menaquinone biosynthesis 4 258 1.5E-91 T 11-10-2018 IPR003773 Menaquinone biosynthesis enzyme TO73_0422 56d6082cc676bd917a7d675c48e81191 272 SUPERFAMILY SSF53850 4 263 1.0E-85 T 11-10-2018 TO73_0422 56d6082cc676bd917a7d675c48e81191 272 Gene3D G3DSA:3.40.190.10 80 172 2.9E-113 T 11-10-2018 TO73_0422 56d6082cc676bd917a7d675c48e81191 272 Gene3D G3DSA:3.40.190.10 6 259 2.9E-113 T 11-10-2018 TO73_0422 56d6082cc676bd917a7d675c48e81191 272 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 3 264 43.764 T 11-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 SUPERFAMILY SSF51735 232 372 7.76E-34 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 Gene3D G3DSA:3.30.70.1450 364 444 1.1E-5 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 Gene3D G3DSA:3.30.70.1450 141 228 5.7E-13 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 PRINTS PR00335 TrkA potassium uptake protein signature 71 85 3.1E-14 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 PRINTS PR00335 TrkA potassium uptake protein signature 58 68 3.1E-14 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.1E-14 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 PRINTS PR00335 TrkA potassium uptake protein signature 18 32 3.1E-14 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 PRINTS PR00335 TrkA potassium uptake protein signature 47 57 3.1E-14 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 SUPERFAMILY SSF116726 136 223 8.24E-12 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 Pfam PF02080 TrkA-C domain 155 224 1.7E-8 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 Gene3D G3DSA:3.40.50.720 1 140 5.5E-34 T 11-10-2018 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 Pfam PF02254 TrkA-N domain 234 346 1.0E-27 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 Pfam PF02254 TrkA-N domain 3 90 3.5E-25 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 SUPERFAMILY SSF51735 1 150 4.27E-31 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1299 e10485a03fae41b9958edb68a6c087fb 445 Gene3D G3DSA:3.40.50.720 232 363 1.3E-39 T 11-10-2018 TO73_2102 6016150d10b02046d5417a72fa7e04d6 398 Gene3D G3DSA:3.40.190.10 133 370 6.2E-140 T 11-10-2018 TO73_2102 6016150d10b02046d5417a72fa7e04d6 398 PRINTS PR00181 Maltose binding protein signature 165 184 6.7E-14 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TO73_2102 6016150d10b02046d5417a72fa7e04d6 398 PRINTS PR00181 Maltose binding protein signature 124 143 6.7E-14 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TO73_2102 6016150d10b02046d5417a72fa7e04d6 398 PRINTS PR00181 Maltose binding protein signature 354 373 6.7E-14 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TO73_2102 6016150d10b02046d5417a72fa7e04d6 398 PRINTS PR00181 Maltose binding protein signature 230 249 6.7E-14 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TO73_2102 6016150d10b02046d5417a72fa7e04d6 398 PRINTS PR00181 Maltose binding protein signature 145 164 6.7E-14 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TO73_2102 6016150d10b02046d5417a72fa7e04d6 398 SUPERFAMILY SSF53850 20 392 1.45E-84 T 11-10-2018 TO73_2102 6016150d10b02046d5417a72fa7e04d6 398 Pfam PF13416 Bacterial extracellular solute-binding protein 39 333 5.3E-47 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein TO73_2102 6016150d10b02046d5417a72fa7e04d6 398 Gene3D G3DSA:3.40.190.10 35 354 6.2E-140 T 11-10-2018 TO73_1116 5f09c557d25d67710e7100d032c41449 150 Gene3D G3DSA:2.30.30.790 11 118 1.1E-20 T 11-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1116 5f09c557d25d67710e7100d032c41449 150 SUPERFAMILY SSF50104 4 117 6.42E-42 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily TO73_1116 5f09c557d25d67710e7100d032c41449 150 PIRSF PIRSF002191 1 140 1.3E-46 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1116 5f09c557d25d67710e7100d032c41449 150 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 6 112 3.7E-39 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1116 5f09c557d25d67710e7100d032c41449 150 ProSitePatterns PS01015 Ribosomal protein L19 signature. 88 103 - T 11-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1116 5f09c557d25d67710e7100d032c41449 150 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 4 116 26.321 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1116 5f09c557d25d67710e7100d032c41449 150 PRINTS PR00061 Ribosomal protein L19 signature 36 65 7.2E-37 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1116 5f09c557d25d67710e7100d032c41449 150 PRINTS PR00061 Ribosomal protein L19 signature 6 35 7.2E-37 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1116 5f09c557d25d67710e7100d032c41449 150 PRINTS PR00061 Ribosomal protein L19 signature 66 89 7.2E-37 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1116 5f09c557d25d67710e7100d032c41449 150 Pfam PF01245 Ribosomal protein L19 6 113 1.4E-42 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0752 4efea264dd409b1104dc397b4892e8c9 151 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 138 2.2E-32 T 11-10-2018 IPR011605 NusB antitermination factor GO:0006353 TO73_0752 4efea264dd409b1104dc397b4892e8c9 151 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 140 16.83 T 11-10-2018 IPR011605 NusB antitermination factor GO:0006353 TO73_0752 4efea264dd409b1104dc397b4892e8c9 151 SUPERFAMILY SSF48013 2 140 2.09E-31 T 11-10-2018 IPR035926 NusB-like superfamily TO73_0752 4efea264dd409b1104dc397b4892e8c9 151 Gene3D G3DSA:1.10.940.10 1 150 3.6E-37 T 11-10-2018 IPR035926 NusB-like superfamily TO73_0752 4efea264dd409b1104dc397b4892e8c9 151 Pfam PF01029 NusB family 3 137 1.7E-31 T 11-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TO73_1835 5d7ea05fa7d8ed762c58ace39ab8ad3b 368 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 6 341 6.8E-73 T 11-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 TO73_1835 5d7ea05fa7d8ed762c58ace39ab8ad3b 368 Pfam PF04055 Radical SAM superfamily 9 167 3.1E-25 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_1835 5d7ea05fa7d8ed762c58ace39ab8ad3b 368 Pfam PF06969 HemN C-terminal domain 291 354 1.9E-15 T 11-10-2018 IPR010723 HemN, C-terminal TO73_1835 5d7ea05fa7d8ed762c58ace39ab8ad3b 368 SUPERFAMILY SSF102114 2 365 1.96E-88 T 11-10-2018 TO73_1835 5d7ea05fa7d8ed762c58ace39ab8ad3b 368 SMART SM00729 4 215 2.8E-50 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_1835 5d7ea05fa7d8ed762c58ace39ab8ad3b 368 Gene3D G3DSA:3.80.30.20 1 269 1.1E-78 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TO73_0497 b956ed105276849955134ad25ce9e576 651 SMART SM00220 96 363 1.4E-72 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TO73_0497 b956ed105276849955134ad25ce9e576 651 Gene3D G3DSA:3.30.200.20 86 175 5.2E-29 T 11-10-2018 TO73_0497 b956ed105276849955134ad25ce9e576 651 Gene3D G3DSA:1.10.510.10 177 372 1.4E-47 T 11-10-2018 TO73_0497 b956ed105276849955134ad25ce9e576 651 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 102 125 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TO73_0497 b956ed105276849955134ad25ce9e576 651 SUPERFAMILY SSF56112 85 356 4.05E-80 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily TO73_0497 b956ed105276849955134ad25ce9e576 651 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 214 226 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TO73_0497 b956ed105276849955134ad25ce9e576 651 SUPERFAMILY SSF63825 380 634 7.06E-22 T 11-10-2018 TO73_0497 b956ed105276849955134ad25ce9e576 651 Pfam PF00069 Protein kinase domain 96 355 1.0E-53 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TO73_0497 b956ed105276849955134ad25ce9e576 651 Gene3D G3DSA:2.120.10.30 444 631 4.0E-19 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TO73_0867 63cf60005bc208fdaf1e0405f12ec037 112 Gene3D G3DSA:3.30.110.70 2 108 1.3E-42 T 11-10-2018 TO73_0867 63cf60005bc208fdaf1e0405f12ec037 112 Pfam PF01906 Putative heavy-metal-binding 1 104 9.6E-39 T 11-10-2018 IPR002765 Uncharacterised protein family UPF0145 TO73_0867 63cf60005bc208fdaf1e0405f12ec037 112 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 24.781 T 11-10-2018 IPR002765 Uncharacterised protein family UPF0145 TO73_0867 63cf60005bc208fdaf1e0405f12ec037 112 SUPERFAMILY SSF117782 1 107 7.85E-38 T 11-10-2018 IPR035439 UPF0145 domain superfamily TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 SUPERFAMILY SSF56059 1 227 1.71E-75 T 11-10-2018 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 PIRSF PIRSF001554 1 377 2.4E-142 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 373 5.7E-143 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 Gene3D G3DSA:3.30.1490.20 21 96 9.9E-98 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 Gene3D G3DSA:3.40.50.261 231 378 7.0E-51 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 248 273 - T 11-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 Pfam PF00549 CoA-ligase 255 368 5.7E-15 T 11-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 SUPERFAMILY SSF52210 231 374 2.88E-46 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 Pfam PF08442 ATP-grasp domain 2 194 1.5E-75 T 11-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 375 40.271 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TO73_1367 b469ae2dcd99ae00dae7439c52d955e5 378 Gene3D G3DSA:3.30.470.20 3 220 9.9E-98 T 11-10-2018 TO73_1596 5dcff2016c93914c2927db033fa3d273 323 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 1 322 22.041 T 11-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TO73_1596 5dcff2016c93914c2927db033fa3d273 323 Pfam PF01992 ATP synthase (C/AC39) subunit 8 318 3.2E-51 T 11-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1596 5dcff2016c93914c2927db033fa3d273 323 Gene3D G3DSA:1.20.1690.10 78 178 1.1E-94 T 11-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1596 5dcff2016c93914c2927db033fa3d273 323 Gene3D G3DSA:1.10.132.50 5 314 1.1E-94 T 11-10-2018 TO73_1596 5dcff2016c93914c2927db033fa3d273 323 SUPERFAMILY SSF103486 5 321 2.48E-70 T 11-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1596 5dcff2016c93914c2927db033fa3d273 323 Gene3D G3DSA:1.20.1690.10 186 281 1.1E-94 T 11-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1550 fdf834a18e99ef9d98fe8ffd70f32653 80 Gene3D G3DSA:1.10.1200.10 1 79 1.1E-30 T 11-10-2018 IPR036736 ACP-like superfamily TO73_1550 fdf834a18e99ef9d98fe8ffd70f32653 80 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 77 8.2E-35 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TO73_1550 fdf834a18e99ef9d98fe8ffd70f32653 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 43 79 2.0E-12 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TO73_1550 fdf834a18e99ef9d98fe8ffd70f32653 80 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 22.852 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TO73_1550 fdf834a18e99ef9d98fe8ffd70f32653 80 ProSitePatterns PS00012 Phosphopantetheine attachment site. 34 49 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site TO73_1550 fdf834a18e99ef9d98fe8ffd70f32653 80 SUPERFAMILY SSF47336 1 79 7.98E-25 T 11-10-2018 IPR036736 ACP-like superfamily TO73_1550 fdf834a18e99ef9d98fe8ffd70f32653 80 Pfam PF00550 Phosphopantetheine attachment site 8 75 2.7E-15 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain TO73_1814 74e253e9a4c70962f40b5d09fb10d715 300 SUPERFAMILY SSF52540 3 222 2.17E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1814 74e253e9a4c70962f40b5d09fb10d715 300 SMART SM00382 27 209 1.3E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1814 74e253e9a4c70962f40b5d09fb10d715 300 Pfam PF00005 ABC transporter 18 160 1.6E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1814 74e253e9a4c70962f40b5d09fb10d715 300 Gene3D G3DSA:3.40.50.300 1 226 1.1E-57 T 11-10-2018 TO73_0444 eecd824f5986f0bf7b4098bf5f56575a 228 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 227 29.768 T 11-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0444 eecd824f5986f0bf7b4098bf5f56575a 228 ProSitePatterns PS01057 SAICAR synthetase signature 1. 81 95 - T 11-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0444 eecd824f5986f0bf7b4098bf5f56575a 228 SUPERFAMILY SSF56104 1 227 8.83E-77 T 11-10-2018 TO73_0444 eecd824f5986f0bf7b4098bf5f56575a 228 Gene3D G3DSA:3.30.200.20 3 224 5.9E-85 T 11-10-2018 TO73_0444 eecd824f5986f0bf7b4098bf5f56575a 228 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 225 6.4E-61 T 11-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TO73_0444 eecd824f5986f0bf7b4098bf5f56575a 228 Pfam PF01259 SAICAR synthetase 3 224 2.6E-56 T 11-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TO73_0444 eecd824f5986f0bf7b4098bf5f56575a 228 Gene3D G3DSA:3.30.470.20 80 213 5.9E-85 T 11-10-2018 TO73_1467 814bb0e5e5e61d70fe695feac767b418 178 SUPERFAMILY SSF101874 2 171 1.18E-54 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TO73_1467 814bb0e5e5e61d70fe695feac767b418 178 Pfam PF04264 YceI-like domain 3 168 1.1E-39 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TO73_1467 814bb0e5e5e61d70fe695feac767b418 178 Gene3D G3DSA:2.40.128.110 1 175 1.8E-53 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TO73_1467 814bb0e5e5e61d70fe695feac767b418 178 SMART SM00867 2 170 2.1E-64 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TO73_0779 0d8836fdce2c55509476d9a37e133a41 349 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 2 326 2.8E-166 T 11-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 TO73_0779 0d8836fdce2c55509476d9a37e133a41 349 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 319 3.2E-142 T 11-10-2018 IPR016040 NAD(P)-binding domain TO73_0779 0d8836fdce2c55509476d9a37e133a41 349 Gene3D G3DSA:3.40.50.720 4 309 5.8E-150 T 11-10-2018 TO73_0779 0d8836fdce2c55509476d9a37e133a41 349 Gene3D G3DSA:3.90.25.10 193 321 5.8E-150 T 11-10-2018 TO73_0779 0d8836fdce2c55509476d9a37e133a41 349 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 329 57.327 T 11-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 TO73_0779 0d8836fdce2c55509476d9a37e133a41 349 SUPERFAMILY SSF51735 2 325 4.62E-82 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0423 f668b0db25ef174d3dc88766b4b954f4 204 SMART SM00100 1 117 2.6E-15 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain TO73_0423 f668b0db25ef174d3dc88766b4b954f4 204 Pfam PF13545 Crp-like helix-turn-helix domain 137 200 7.4E-17 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_0423 f668b0db25ef174d3dc88766b4b954f4 204 Pfam PF00027 Cyclic nucleotide-binding domain 20 103 1.1E-15 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain TO73_0423 f668b0db25ef174d3dc88766b4b954f4 204 Gene3D G3DSA:1.10.10.10 135 201 3.1E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0423 f668b0db25ef174d3dc88766b4b954f4 204 SMART SM00419 147 193 2.7E-7 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_0423 f668b0db25ef174d3dc88766b4b954f4 204 SUPERFAMILY SSF51206 1 128 1.44E-22 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like TO73_0423 f668b0db25ef174d3dc88766b4b954f4 204 SUPERFAMILY SSF46785 134 200 6.53E-14 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0423 f668b0db25ef174d3dc88766b4b954f4 204 Gene3D G3DSA:2.60.120.10 1 134 7.8E-24 T 11-10-2018 IPR014710 RmlC-like jelly roll fold TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SUPERFAMILY SSF48452 23 144 4.07E-25 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SUPERFAMILY SSF48452 152 367 1.6E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SUPERFAMILY SSF48452 338 441 2.28E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 Gene3D G3DSA:1.25.40.10 234 310 9.9E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 Pfam PF00515 Tetratricopeptide repeat 87 118 1.0E-8 T 11-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SMART SM00028 18 51 11.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SMART SM00028 250 283 120.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SMART SM00028 52 85 4.4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SMART SM00028 186 219 110.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SMART SM00028 86 119 4.8E-7 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SMART SM00028 407 440 0.056 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 SMART SM00028 373 406 230.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 Gene3D G3DSA:1.25.40.10 13 233 9.4E-36 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 Pfam PF13432 Tetratricopeptide repeat 22 77 3.1E-10 T 11-10-2018 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 Pfam PF13432 Tetratricopeptide repeat 237 281 0.0033 T 11-10-2018 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 Pfam PF13432 Tetratricopeptide repeat 379 439 2.3E-5 T 11-10-2018 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 Pfam PF13432 Tetratricopeptide repeat 156 213 4.0E-4 T 11-10-2018 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 Gene3D G3DSA:1.25.40.10 312 442 1.5E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0410 d925673dfce5264b8acfcbf371b6e919 447 Pfam PF07721 Tetratricopeptide repeat 340 364 0.045 T 11-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 TO73_1772 66862d31624632006019ebdb8910f21a 164 Gene3D G3DSA:3.90.1140.10 2 164 1.2E-23 T 11-10-2018 TO73_1772 66862d31624632006019ebdb8910f21a 164 Pfam PF13563 2'-5' RNA ligase superfamily 8 151 1.1E-18 T 11-10-2018 TO73_1772 66862d31624632006019ebdb8910f21a 164 SUPERFAMILY SSF55144 2 163 1.39E-24 T 11-10-2018 IPR009097 Cyclic phosphodiesterase TO73_1446 489d6faceacb9fa30f2ea800ac60bb16 648 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 85 6.0E-23 T 11-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TO73_1446 489d6faceacb9fa30f2ea800ac60bb16 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 534 612 8.1E-32 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TO73_1446 489d6faceacb9fa30f2ea800ac60bb16 648 Gene3D G3DSA:3.30.300.30 521 647 2.3E-33 T 11-10-2018 TO73_1446 489d6faceacb9fa30f2ea800ac60bb16 648 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 9 648 54.242 T 11-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 TO73_1446 489d6faceacb9fa30f2ea800ac60bb16 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 263 274 - T 11-10-2018 IPR020845 AMP-binding, conserved site TO73_1446 489d6faceacb9fa30f2ea800ac60bb16 648 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 28 646 0.0 T 11-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 TO73_1446 489d6faceacb9fa30f2ea800ac60bb16 648 Pfam PF00501 AMP-binding enzyme 95 525 5.6E-98 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_1446 489d6faceacb9fa30f2ea800ac60bb16 648 SUPERFAMILY SSF56801 17 644 6.54E-191 T 11-10-2018 TO73_1446 489d6faceacb9fa30f2ea800ac60bb16 648 Gene3D G3DSA:3.40.50.12780 62 518 4.6E-111 T 11-10-2018 TO73_1569 7b9b0418b392122fa432a406c8460788 360 Gene3D G3DSA:3.40.220.10 1 148 4.2E-43 T 11-10-2018 TO73_1569 7b9b0418b392122fa432a406c8460788 360 SUPERFAMILY SSF52949 1 149 2.19E-44 T 11-10-2018 TO73_1569 7b9b0418b392122fa432a406c8460788 360 Pfam PF01661 Macro domain 18 130 2.9E-22 T 11-10-2018 IPR002589 Macro domain TO73_1569 7b9b0418b392122fa432a406c8460788 360 SMART SM00506 1 132 6.2E-24 T 11-10-2018 IPR002589 Macro domain TO73_2257 71518fab332da42725eee98b3026ffa7 420 SUPERFAMILY SSF81648 228 372 9.42E-19 T 11-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TO73_2257 71518fab332da42725eee98b3026ffa7 420 SUPERFAMILY SSF81342 3 267 3.45E-56 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TO73_2257 71518fab332da42725eee98b3026ffa7 420 Gene3D G3DSA:1.20.810.10 1 418 1.8E-97 T 11-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 TO73_2257 71518fab332da42725eee98b3026ffa7 420 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 97 272 8.0E-47 T 11-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TO73_2257 71518fab332da42725eee98b3026ffa7 420 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 278 373 1.2E-7 T 11-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TO73_0902 3feda9fccd7625bedec4079f25d35867 626 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 17 623 8.7E-147 T 11-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TO73_0902 3feda9fccd7625bedec4079f25d35867 626 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 115 548 6.1E-76 T 11-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TO73_2020 bbc6d23bed5dcb16124977af41b8e748 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 261 1.3E-38 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TO73_2020 bbc6d23bed5dcb16124977af41b8e748 262 Gene3D G3DSA:3.90.226.10 1 205 3.7E-67 T 11-10-2018 TO73_2020 bbc6d23bed5dcb16124977af41b8e748 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TO73_2020 bbc6d23bed5dcb16124977af41b8e748 262 Gene3D G3DSA:1.10.12.10 206 262 7.7E-29 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TO73_2020 bbc6d23bed5dcb16124977af41b8e748 262 SUPERFAMILY SSF52096 16 261 3.03E-60 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_0988 f0ece614d143e87247bdeec66f8db172 173 Pfam PF06243 Phenylacetic acid degradation B 5 168 4.1E-37 T 11-10-2018 IPR009359 Phenylacetic acid degradation B TO73_0988 f0ece614d143e87247bdeec66f8db172 173 Gene3D G3DSA:3.10.20.520 2 64 2.6E-18 T 11-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B TO73_0631 8f43e2b1424b7d599eca42435352be85 247 SUPERFAMILY SSF142823 13 226 2.48E-53 T 11-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TO73_0631 8f43e2b1424b7d599eca42435352be85 247 Pfam PF04029 2-phosphosulpholactate phosphatase 12 224 4.2E-66 T 11-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TO73_0631 8f43e2b1424b7d599eca42435352be85 247 Gene3D G3DSA:3.90.1560.10 1 237 4.2E-81 T 11-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TO73_2185 f31a1eb68405634ab05d5d43bd0b32da 406 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 171 362 7.8E-72 T 11-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TO73_2185 f31a1eb68405634ab05d5d43bd0b32da 406 Pfam PF02926 THUMP domain 68 157 2.4E-10 T 11-10-2018 IPR004114 THUMP domain GO:0003723 TO73_2185 f31a1eb68405634ab05d5d43bd0b32da 406 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 366 2.3E-99 T 11-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TO73_2185 f31a1eb68405634ab05d5d43bd0b32da 406 SMART SM00981 73 161 1.2E-11 T 11-10-2018 IPR004114 THUMP domain GO:0003723 TO73_2185 f31a1eb68405634ab05d5d43bd0b32da 406 Gene3D G3DSA:3.40.50.620 171 383 3.0E-73 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_2185 f31a1eb68405634ab05d5d43bd0b32da 406 Gene3D G3DSA:3.30.2130.30 1 169 2.0E-35 T 11-10-2018 TO73_2185 f31a1eb68405634ab05d5d43bd0b32da 406 SUPERFAMILY SSF143437 5 169 4.19E-30 T 11-10-2018 TO73_2185 f31a1eb68405634ab05d5d43bd0b32da 406 SUPERFAMILY SSF52402 173 366 2.65E-50 T 11-10-2018 TO73_2185 f31a1eb68405634ab05d5d43bd0b32da 406 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 406 118.389 T 11-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 Gene3D G3DSA:3.90.226.10 450 643 5.4E-28 T 11-10-2018 TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 SUPERFAMILY SSF51735 1 187 2.88E-42 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 283 2.1E-17 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 SUPERFAMILY SSF48179 187 303 1.19E-25 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 SUPERFAMILY SSF52096 451 759 1.46E-35 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 185 6.8E-48 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 Gene3D G3DSA:3.40.50.720 1 189 3.8E-59 T 11-10-2018 TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 SUPERFAMILY SSF48179 333 394 4.0E-8 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 Gene3D G3DSA:1.10.1040.10 190 301 7.3E-21 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TO73_1062 3238ed5be34f18b67b45ddc9809c6c82 763 Pfam PF00378 Enoyl-CoA hydratase/isomerase 458 594 8.0E-12 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TO73_1149 59cef9e4a656532bea13a996585966bc 116 Gene3D G3DSA:2.40.40.20 1 115 2.7E-50 T 11-10-2018 TO73_1149 59cef9e4a656532bea13a996585966bc 116 SUPERFAMILY SSF50692 1 113 1.86E-47 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TO73_1149 59cef9e4a656532bea13a996585966bc 116 PIRSF PIRSF006246 1 116 1.2E-51 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TO73_1149 59cef9e4a656532bea13a996585966bc 116 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 1 86 3.0E-40 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TO73_1149 59cef9e4a656532bea13a996585966bc 116 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 113 3.4E-45 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TO73_1149 59cef9e4a656532bea13a996585966bc 116 Pfam PF02261 Aspartate decarboxylase 1 110 3.1E-49 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TO73_1149 59cef9e4a656532bea13a996585966bc 116 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 116 68.637 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TO73_0791 c8a82e6a757e2b672b517015e04830f9 127 Gene3D G3DSA:1.20.120.330 10 127 2.0E-43 T 11-10-2018 TO73_0791 c8a82e6a757e2b672b517015e04830f9 127 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 11 126 2.4E-19 T 11-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 TO73_0791 c8a82e6a757e2b672b517015e04830f9 127 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 7 126 1.0E-27 T 11-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 TO73_0791 c8a82e6a757e2b672b517015e04830f9 127 SUPERFAMILY SSF81593 3 125 1.49E-30 T 11-10-2018 TO73_0698 b938495445b69e9ec4ba6129567a9fd9 155 Pfam PF03061 Thioesterase superfamily 54 138 2.6E-9 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TO73_0698 b938495445b69e9ec4ba6129567a9fd9 155 SUPERFAMILY SSF54637 2 146 1.58E-33 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_0698 b938495445b69e9ec4ba6129567a9fd9 155 Gene3D G3DSA:3.10.129.10 1 152 1.3E-40 T 11-10-2018 TO73_2186 6cd99803ca4bfbb389ec0f38b8fa0a0f 434 ProSitePatterns PS00571 Amidases signature. 145 176 - T 11-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TO73_2186 6cd99803ca4bfbb389ec0f38b8fa0a0f 434 Gene3D G3DSA:3.90.1300.10 1 434 1.3E-178 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TO73_2186 6cd99803ca4bfbb389ec0f38b8fa0a0f 434 SUPERFAMILY SSF75304 2 433 5.49E-122 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TO73_2186 6cd99803ca4bfbb389ec0f38b8fa0a0f 434 Pfam PF01425 Amidase 20 423 1.5E-93 T 11-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TO73_1547 ffea4f63d14c3cae85b0ce8c2e90fa98 148 Pfam PF02082 Transcriptional regulator 1 82 8.1E-27 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type TO73_1547 ffea4f63d14c3cae85b0ce8c2e90fa98 148 Gene3D G3DSA:1.10.10.10 1 140 4.4E-48 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1547 ffea4f63d14c3cae85b0ce8c2e90fa98 148 SUPERFAMILY SSF46785 4 132 6.46E-36 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1547 ffea4f63d14c3cae85b0ce8c2e90fa98 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 4.6E-43 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type TO73_2505 7b2469eda6fa906d81b81b634627ab45 203 Gene3D G3DSA:3.90.70.10 36 172 2.8E-19 T 11-10-2018 TO73_2505 7b2469eda6fa906d81b81b634627ab45 203 Pfam PF03412 Peptidase C39 family 33 169 1.3E-13 T 11-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 TO73_0256 abf8bedc32135c32bc4eda9aafed6c2d 169 Gene3D G3DSA:1.10.760.10 61 154 2.1E-13 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0256 abf8bedc32135c32bc4eda9aafed6c2d 169 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 72 150 8.7E-12 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0256 abf8bedc32135c32bc4eda9aafed6c2d 169 SUPERFAMILY SSF46626 4 152 2.06E-16 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0548 1b29ccbbfe75fbabff59fddac3764cd6 120 Pfam PF09685 Domain of unknown function (DUF4870) 10 119 7.5E-23 T 11-10-2018 IPR019109 Protein of unknown function DUF4870 TO73_1556 6e92c9cbb74734f63b5e09fbd4166fb6 198 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 194 29.31 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TO73_1556 6e92c9cbb74734f63b5e09fbd4166fb6 198 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 189 1.2E-47 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TO73_1556 6e92c9cbb74734f63b5e09fbd4166fb6 198 Pfam PF00117 Glutamine amidotransferase class-I 5 183 1.5E-11 T 11-10-2018 IPR017926 Glutamine amidotransferase TO73_1556 6e92c9cbb74734f63b5e09fbd4166fb6 198 Gene3D G3DSA:3.40.50.880 1 198 2.6E-62 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1556 6e92c9cbb74734f63b5e09fbd4166fb6 198 PIRSF PIRSF000495 1 196 2.0E-55 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TO73_1556 6e92c9cbb74734f63b5e09fbd4166fb6 198 SUPERFAMILY SSF52317 2 188 3.3E-45 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1577 7f701987b61e1bd28a059c67e3963b5d 181 Gene3D G3DSA:3.40.50.12280 1 181 3.0E-91 T 11-10-2018 TO73_1577 7f701987b61e1bd28a059c67e3963b5d 181 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 19 160 8.0E-75 T 11-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1577 7f701987b61e1bd28a059c67e3963b5d 181 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 126 142 - T 11-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1577 7f701987b61e1bd28a059c67e3963b5d 181 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 45 154 7.0E-26 T 11-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1577 7f701987b61e1bd28a059c67e3963b5d 181 SUPERFAMILY SSF56770 17 164 6.28E-68 T 11-10-2018 TO73_1577 7f701987b61e1bd28a059c67e3963b5d 181 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 12 159 43.892 T 11-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1905 3dbfe2d5c6dbcf7d464c1e3a6254f97a 406 Hamap MF_01402_B 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 16 397 59.277 T 11-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_1905 3dbfe2d5c6dbcf7d464c1e3a6254f97a 406 Gene3D G3DSA:3.30.70.2130 92 233 4.3E-99 T 11-10-2018 TO73_1905 3dbfe2d5c6dbcf7d464c1e3a6254f97a 406 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 51 220 7.1E-49 T 11-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_1905 3dbfe2d5c6dbcf7d464c1e3a6254f97a 406 Gene3D G3DSA:3.40.720.10 19 392 4.3E-99 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TO73_1905 3dbfe2d5c6dbcf7d464c1e3a6254f97a 406 Pfam PF01676 Metalloenzyme superfamily 17 394 3.4E-32 T 11-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TO73_1905 3dbfe2d5c6dbcf7d464c1e3a6254f97a 406 PIRSF PIRSF006392 13 402 9.5E-127 T 11-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_1905 3dbfe2d5c6dbcf7d464c1e3a6254f97a 406 SUPERFAMILY SSF53649 16 375 8.29E-33 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TO73_1905 3dbfe2d5c6dbcf7d464c1e3a6254f97a 406 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 19 395 3.9E-85 T 11-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_1096 a1b61114217a45fc8f88dcd17f55658a 341 SUPERFAMILY SSF52518 10 329 1.64E-101 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_1096 a1b61114217a45fc8f88dcd17f55658a 341 Pfam PF00676 Dehydrogenase E1 component 20 309 5.2E-88 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TO73_1096 a1b61114217a45fc8f88dcd17f55658a 341 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 8 329 3.6E-135 T 11-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TO73_1096 a1b61114217a45fc8f88dcd17f55658a 341 Gene3D G3DSA:3.40.50.970 4 334 1.9E-115 T 11-10-2018 TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 SUPERFAMILY SSF82114 161 293 1.13E-42 T 11-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 SMART SM00904 170 293 1.4E-58 T 11-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 Pfam PF06574 FAD synthetase 13 153 7.0E-37 T 11-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 Gene3D G3DSA:2.40.30.30 175 293 5.8E-41 T 11-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 15 77 6.0E-8 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 Gene3D G3DSA:3.40.50.620 3 173 1.1E-47 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 Pfam PF01687 Riboflavin kinase 171 292 2.2E-35 T 11-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 SUPERFAMILY SSF52374 14 171 9.01E-28 T 11-10-2018 TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 16 292 8.6E-77 T 11-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TO73_1775 a0c977a59656d38fdf5e345cab5ad614 294 PIRSF PIRSF004491 2 293 1.0E-95 T 11-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TO73_0881 8ef95743a1a82ea40ff315221495dd39 250 SMART SM00382 26 208 9.2E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0881 8ef95743a1a82ea40ff315221495dd39 250 Gene3D G3DSA:3.40.50.300 1 245 4.5E-69 T 11-10-2018 TO73_0881 8ef95743a1a82ea40ff315221495dd39 250 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0881 8ef95743a1a82ea40ff315221495dd39 250 SUPERFAMILY SSF52540 2 221 1.61E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0881 8ef95743a1a82ea40ff315221495dd39 250 Pfam PF00005 ABC transporter 18 161 2.5E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1266 7285f6c7c69318de07f3e5f9bd4a5ae7 391 Gene3D G3DSA:3.40.190.10 24 366 2.9E-160 T 11-10-2018 TO73_1266 7285f6c7c69318de07f3e5f9bd4a5ae7 391 SUPERFAMILY SSF53850 18 347 1.43E-62 T 11-10-2018 TO73_1266 7285f6c7c69318de07f3e5f9bd4a5ae7 391 Pfam PF01547 Bacterial extracellular solute-binding protein 32 325 2.1E-29 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein TO73_1266 7285f6c7c69318de07f3e5f9bd4a5ae7 391 Gene3D G3DSA:3.40.190.10 141 385 2.9E-160 T 11-10-2018 TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 SMART SM00564 388 417 120.0 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 SMART SM00564 464 496 0.01 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 SMART SM00564 505 536 3.0E-5 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 SMART SM00564 425 457 1.7 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 SMART SM00564 543 574 270.0 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 Gene3D G3DSA:3.30.200.20 1 87 1.2E-25 T 11-10-2018 TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 Pfam PF13360 PQQ-like domain 465 572 9.1E-14 T 11-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 Pfam PF13360 PQQ-like domain 376 457 1.8E-6 T 11-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 Gene3D G3DSA:2.130.10.10 369 604 1.1E-43 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 Gene3D G3DSA:1.10.510.10 101 270 3.9E-47 T 11-10-2018 TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 SUPERFAMILY SSF50998 374 564 2.83E-24 T 11-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 127 139 - T 11-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 Pfam PF00069 Protein kinase domain 10 262 9.0E-47 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TO73_1977 083f3ef8a2953dd73eceec24e5c6b115 605 SUPERFAMILY SSF56112 5 264 2.97E-72 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily TO73_1975 a262fce33dd4ffb95edac04f311acc50 432 Gene3D G3DSA:3.65.10.10 16 421 7.7E-139 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TO73_1975 a262fce33dd4ffb95edac04f311acc50 432 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 13 421 1.2E-141 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1975 a262fce33dd4ffb95edac04f311acc50 432 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 17 414 2.6E-73 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TO73_1975 a262fce33dd4ffb95edac04f311acc50 432 SUPERFAMILY SSF55205 14 422 1.55E-108 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TO73_1975 a262fce33dd4ffb95edac04f311acc50 432 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 11 424 36.346 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1975 a262fce33dd4ffb95edac04f311acc50 432 Gene3D G3DSA:3.65.10.10 31 238 7.7E-139 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TO73_0386 5b01d54026e8902be40c0ccd8c39bb9b 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 11-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0386 5b01d54026e8902be40c0ccd8c39bb9b 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 8.7E-57 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TO73_0386 5b01d54026e8902be40c0ccd8c39bb9b 122 SUPERFAMILY SSF50193 1 122 4.45E-53 T 11-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0386 5b01d54026e8902be40c0ccd8c39bb9b 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.5E-58 T 11-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 TO73_0386 5b01d54026e8902be40c0ccd8c39bb9b 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.811 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TO73_0386 5b01d54026e8902be40c0ccd8c39bb9b 122 Gene3D G3DSA:2.40.150.20 1 122 5.5E-57 T 11-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0386 5b01d54026e8902be40c0ccd8c39bb9b 122 SMART SM01374 1 122 3.9E-88 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TO73_0847 f963c1218236fc79b77d8eb0d8d8f627 280 Gene3D G3DSA:3.30.1180.10 158 277 3.5E-25 T 11-10-2018 TO73_0847 f963c1218236fc79b77d8eb0d8d8f627 280 SUPERFAMILY SSF82549 6 276 7.59E-67 T 11-10-2018 TO73_0847 f963c1218236fc79b77d8eb0d8d8f627 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 7 276 6.2E-61 T 11-10-2018 IPR003797 DegV TO73_0847 f963c1218236fc79b77d8eb0d8d8f627 280 Gene3D G3DSA:3.40.50.10170 5 150 7.2E-35 T 11-10-2018 TO73_0847 f963c1218236fc79b77d8eb0d8d8f627 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 8 275 2.0E-66 T 11-10-2018 IPR003797 DegV TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 185 5.4E-4 T 11-10-2018 TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 SUPERFAMILY SSF51735 2 232 2.0E-48 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.2E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.2E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 4.2E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.2E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.2E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.2E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 Pfam PF00106 short chain dehydrogenase 3 194 1.5E-33 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1432 d64ed0e7a3294da724bf52691bac1b06 244 Gene3D G3DSA:3.40.50.720 1 242 9.7E-51 T 11-10-2018 TO73_0814 98e4316d3d8d5da6d790d3c4150e46da 421 Pfam PF13481 AAA domain 7 179 5.7E-23 T 11-10-2018 TO73_0814 98e4316d3d8d5da6d790d3c4150e46da 421 SUPERFAMILY SSF52540 8 234 2.59E-16 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0814 98e4316d3d8d5da6d790d3c4150e46da 421 Gene3D G3DSA:3.40.50.300 6 252 3.7E-29 T 11-10-2018 TO73_1747 5ef61c42e1a909e71c705a56dc239f0c 210 SUPERFAMILY SSF54631 1 132 2.27E-38 T 11-10-2018 TO73_1747 5ef61c42e1a909e71c705a56dc239f0c 210 Pfam PF00571 CBS domain 3 56 2.4E-16 T 11-10-2018 IPR000644 CBS domain TO73_1747 5ef61c42e1a909e71c705a56dc239f0c 210 Pfam PF00571 CBS domain 77 130 6.8E-15 T 11-10-2018 IPR000644 CBS domain TO73_1747 5ef61c42e1a909e71c705a56dc239f0c 210 Gene3D G3DSA:3.10.580.10 1 140 2.7E-43 T 11-10-2018 TO73_1747 5ef61c42e1a909e71c705a56dc239f0c 210 SMART SM00116 10 57 3.6E-14 T 11-10-2018 IPR000644 CBS domain TO73_1747 5ef61c42e1a909e71c705a56dc239f0c 210 SMART SM00116 84 131 3.6E-12 T 11-10-2018 IPR000644 CBS domain TO73_1045 be57f7d0b9d389cf9a013502a1daea8b 313 SMART SM00893 2 184 8.0E-14 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TO73_1045 be57f7d0b9d389cf9a013502a1daea8b 313 PIRSF PIRSF000089 1 313 1.1E-92 T 11-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 TO73_1045 be57f7d0b9d389cf9a013502a1daea8b 313 Pfam PF01012 Electron transfer flavoprotein domain 2 170 1.1E-22 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TO73_1045 be57f7d0b9d389cf9a013502a1daea8b 313 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 188 271 2.3E-35 T 11-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 TO73_1045 be57f7d0b9d389cf9a013502a1daea8b 313 SUPERFAMILY SSF52402 2 178 1.88E-24 T 11-10-2018 TO73_1045 be57f7d0b9d389cf9a013502a1daea8b 313 Gene3D G3DSA:3.40.50.1220 186 313 4.5E-58 T 11-10-2018 TO73_1045 be57f7d0b9d389cf9a013502a1daea8b 313 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 252 278 - T 11-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 TO73_1045 be57f7d0b9d389cf9a013502a1daea8b 313 SUPERFAMILY SSF52467 186 307 2.18E-48 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TO73_1045 be57f7d0b9d389cf9a013502a1daea8b 313 Gene3D G3DSA:3.40.50.620 1 185 1.1E-26 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1174 16389193f3fb7d46a6186b1e72bd8448 345 Pfam PF04865 Baseplate J-like protein 69 272 1.8E-37 T 11-10-2018 IPR006949 Baseplate protein J-like TO73_1124 cb26bfd4dcad49238bb26a4b952c0b22 345 SUPERFAMILY SSF111337 4 345 1.31E-127 T 11-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TO73_1124 cb26bfd4dcad49238bb26a4b952c0b22 345 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 2 345 44.155 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TO73_1124 cb26bfd4dcad49238bb26a4b952c0b22 345 Gene3D G3DSA:3.40.1780.10 1 71 1.1E-17 T 11-10-2018 TO73_1124 cb26bfd4dcad49238bb26a4b952c0b22 345 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 4 345 1.8E-108 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TO73_1124 cb26bfd4dcad49238bb26a4b952c0b22 345 Gene3D G3DSA:3.40.1780.10 152 345 5.4E-80 T 11-10-2018 TO73_1124 cb26bfd4dcad49238bb26a4b952c0b22 345 Pfam PF02547 Queuosine biosynthesis protein 5 344 3.1E-128 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TO73_1124 cb26bfd4dcad49238bb26a4b952c0b22 345 Gene3D G3DSA:2.40.10.240 72 151 1.9E-29 T 11-10-2018 TO73_0678 f12472c0902be8f3571471fcfd791bde 122 SUPERFAMILY SSF53927 5 121 3.2E-34 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TO73_0678 f12472c0902be8f3571471fcfd791bde 122 Gene3D G3DSA:3.40.140.10 2 122 9.2E-36 T 11-10-2018 TO73_0678 f12472c0902be8f3571471fcfd791bde 122 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 4 121 1.0E-34 T 11-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 TO73_0678 f12472c0902be8f3571471fcfd791bde 122 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 97 8.1E-11 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TO73_0678 f12472c0902be8f3571471fcfd791bde 122 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 89 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TO73_2376 ea5ccc94fb4159208b30fa899808d1d3 349 Gene3D G3DSA:1.20.1250.20 1 348 6.2E-24 T 11-10-2018 TO73_2376 ea5ccc94fb4159208b30fa899808d1d3 349 SUPERFAMILY SSF103473 4 345 1.83E-30 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_2376 ea5ccc94fb4159208b30fa899808d1d3 349 Pfam PF07690 Major Facilitator Superfamily 6 321 6.7E-20 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_1078 0ae6fb268e18f1ecdbbe1dda8f776cba 369 Gene3D G3DSA:3.20.20.140 16 356 1.2E-88 T 11-10-2018 TO73_1078 0ae6fb268e18f1ecdbbe1dda8f776cba 369 Pfam PF01979 Amidohydrolase family 61 366 9.6E-32 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TO73_1078 0ae6fb268e18f1ecdbbe1dda8f776cba 369 SUPERFAMILY SSF51556 61 353 1.57E-64 T 11-10-2018 IPR032466 Metal-dependent hydrolase TO73_1078 0ae6fb268e18f1ecdbbe1dda8f776cba 369 SUPERFAMILY SSF51338 8 78 4.32E-14 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TO73_1078 0ae6fb268e18f1ecdbbe1dda8f776cba 369 Gene3D G3DSA:2.30.40.10 8 367 1.2E-88 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TO73_1175 2bc84fd31f1ef89f85960d29ac49356b 120 SUPERFAMILY SSF160719 21 85 4.18E-9 T 11-10-2018 TO73_1442 3d65fef66d3db525658eae62ea415bab 101 Pfam PF01638 HxlR-like helix-turn-helix 22 92 4.9E-16 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type TO73_1442 3d65fef66d3db525658eae62ea415bab 101 Gene3D G3DSA:1.10.10.10 4 100 2.0E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1442 3d65fef66d3db525658eae62ea415bab 101 SUPERFAMILY SSF46785 7 94 1.54E-19 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1853 8449ed0380b59a64b2ffee5159244ba4 247 Gene3D G3DSA:3.30.70.930 1 75 1.0E-10 T 11-10-2018 IPR029756 MTH1187/YkoF-like TO73_1853 8449ed0380b59a64b2ffee5159244ba4 247 Pfam PF07615 YKOF-related Family 3 64 6.2E-6 T 11-10-2018 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative TO73_1853 8449ed0380b59a64b2ffee5159244ba4 247 Gene3D G3DSA:3.40.50.150 85 240 2.2E-27 T 11-10-2018 TO73_1853 8449ed0380b59a64b2ffee5159244ba4 247 SUPERFAMILY SSF89957 1 112 1.7E-23 T 11-10-2018 IPR029756 MTH1187/YkoF-like TO73_1853 8449ed0380b59a64b2ffee5159244ba4 247 Pfam PF08241 Methyltransferase domain 109 192 9.4E-19 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TO73_1853 8449ed0380b59a64b2ffee5159244ba4 247 SUPERFAMILY SSF53335 98 226 2.76E-26 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1269 5bae7a3c70272baf4b97791336ca82b7 250 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1269 5bae7a3c70272baf4b97791336ca82b7 250 Pfam PF00005 ABC transporter 15 163 1.4E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1269 5bae7a3c70272baf4b97791336ca82b7 250 Gene3D G3DSA:3.40.50.300 10 240 5.3E-65 T 11-10-2018 TO73_1269 5bae7a3c70272baf4b97791336ca82b7 250 SMART SM00382 24 214 2.6E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1269 5bae7a3c70272baf4b97791336ca82b7 250 SUPERFAMILY SSF52540 11 225 5.33E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 159 317 2.8E-12 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 Pfam PF01926 50S ribosome-binding GTPase 160 279 1.3E-22 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 11-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 Hamap MF_01454 GTPase Obg [obg]. 2 325 45.183 T 11-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 6.3E-33 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 6.3E-33 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 6.3E-33 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 6.3E-33 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 Pfam PF01018 GTP1/OBG 5 156 1.0E-56 T 11-10-2018 IPR006169 GTP1/OBG domain TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 Gene3D G3DSA:2.40.240.60 343 416 1.2E-27 T 11-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 SUPERFAMILY SSF52540 149 329 8.94E-52 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 Gene3D G3DSA:3.40.50.300 156 328 9.0E-56 T 11-10-2018 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 SUPERFAMILY SSF102741 343 416 8.5E-17 T 11-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 Pfam PF09269 Domain of unknown function (DUF1967) 351 413 2.0E-17 T 11-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 346 413 2.6E-19 T 11-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 Gene3D G3DSA:2.70.210.12 2 155 2.3E-61 T 11-10-2018 IPR036726 GTP1/OBG domain superfamily TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 SUPERFAMILY SSF82051 3 156 4.97E-52 T 11-10-2018 IPR036726 GTP1/OBG domain superfamily TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 PIRSF PIRSF002401 1 352 1.1E-129 T 11-10-2018 IPR035101 GTP-binding protein, Obg-type TO73_0216 8d9fd37de3538c5dec495b8d2906ca03 417 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 324 6.3E-127 T 11-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TO73_0172 e0033203927c92a00e20ba6f4b6d0331 110 ProSitePatterns PS00501 Signal peptidases I serine active site. 31 38 - T 11-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 TO73_0172 e0033203927c92a00e20ba6f4b6d0331 110 Pfam PF00717 Peptidase S24-like 28 95 5.3E-16 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TO73_0172 e0033203927c92a00e20ba6f4b6d0331 110 SUPERFAMILY SSF51306 22 109 3.66E-25 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TO73_0172 e0033203927c92a00e20ba6f4b6d0331 110 Gene3D G3DSA:2.10.109.10 3 109 2.1E-19 T 11-10-2018 TO73_1861 fc70e74ab939b5ef5cf1a86c55f0cbf7 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 303 6.5E-17 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TO73_1861 fc70e74ab939b5ef5cf1a86c55f0cbf7 327 Pfam PF00005 ABC transporter 35 186 5.6E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1861 fc70e74ab939b5ef5cf1a86c55f0cbf7 327 SUPERFAMILY SSF52540 7 257 8.37E-79 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1861 fc70e74ab939b5ef5cf1a86c55f0cbf7 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 322 3.3E-27 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TO73_1861 fc70e74ab939b5ef5cf1a86c55f0cbf7 327 SMART SM00382 43 236 5.3E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1861 fc70e74ab939b5ef5cf1a86c55f0cbf7 327 Gene3D G3DSA:3.40.50.300 5 326 2.2E-108 T 11-10-2018 TO73_1861 fc70e74ab939b5ef5cf1a86c55f0cbf7 327 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 Gene3D G3DSA:1.10.8.60 169 244 3.3E-29 T 11-10-2018 TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 323 157.84 T 11-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 4 223 9.0E-106 T 11-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 239 314 4.0E-32 T 11-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 242 314 1.1E-31 T 11-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 10 314 2.7E-142 T 11-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 Gene3D G3DSA:1.10.10.10 245 323 1.5E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 Gene3D G3DSA:3.40.50.300 3 168 4.7E-44 T 11-10-2018 TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 SMART SM00382 38 170 2.0E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 SUPERFAMILY SSF46785 244 318 3.21E-25 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1792 ce12b18e00d4e716663367b762a9ee7d 323 SUPERFAMILY SSF52540 7 238 3.31E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2145 6d72dcd600a3a90eb0a84eeae10f38b1 200 Gene3D G3DSA:3.40.30.10 24 198 4.7E-55 T 11-10-2018 TO73_2145 6d72dcd600a3a90eb0a84eeae10f38b1 200 Pfam PF02630 SCO1/SenC 50 167 3.6E-37 T 11-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2145 6d72dcd600a3a90eb0a84eeae10f38b1 200 SUPERFAMILY SSF52833 38 192 1.04E-44 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1471 15a27881065026d31ed3171a40311da4 359 Pfam PF01842 ACT domain 294 349 6.4E-9 T 11-10-2018 IPR002912 ACT domain TO73_1471 15a27881065026d31ed3171a40311da4 359 Gene3D G3DSA:3.40.50.720 6 177 1.8E-45 T 11-10-2018 TO73_1471 15a27881065026d31ed3171a40311da4 359 Gene3D G3DSA:3.30.70.260 292 357 1.6E-9 T 11-10-2018 TO73_1471 15a27881065026d31ed3171a40311da4 359 SUPERFAMILY SSF55021 291 358 6.22E-10 T 11-10-2018 TO73_1471 15a27881065026d31ed3171a40311da4 359 SUPERFAMILY SSF51735 7 168 3.75E-40 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1471 15a27881065026d31ed3171a40311da4 359 SUPERFAMILY SSF48179 175 280 4.08E-26 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TO73_1471 15a27881065026d31ed3171a40311da4 359 Gene3D G3DSA:1.10.3660.10 178 281 1.7E-27 T 11-10-2018 TO73_1471 15a27881065026d31ed3171a40311da4 359 Pfam PF02153 Prephenate dehydrogenase 20 262 6.8E-54 T 11-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TO73_0905 f80ccb3464c6ea4c5909be6faa47e197 325 Gene3D G3DSA:3.30.200.20 1 101 1.0E-5 T 11-10-2018 TO73_0905 f80ccb3464c6ea4c5909be6faa47e197 325 Pfam PF01636 Phosphotransferase enzyme family 21 249 1.6E-33 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase TO73_0905 f80ccb3464c6ea4c5909be6faa47e197 325 SUPERFAMILY SSF56112 2 320 4.7E-46 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily TO73_0905 f80ccb3464c6ea4c5909be6faa47e197 325 Gene3D G3DSA:3.90.1200.10 107 313 4.7E-45 T 11-10-2018 TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 6.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 6.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 6.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.5E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 9.5E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 9.5E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 9.5E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 9.5E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 9.5E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 Gene3D G3DSA:3.40.50.720 1 256 2.4E-85 T 11-10-2018 TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 246 1.7E-65 T 11-10-2018 TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TO73_2068 16da5ea56fe6fc10f12ac87ce052dd9c 256 SUPERFAMILY SSF51735 5 247 1.01E-77 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 195 325 8.1E-14 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 SUPERFAMILY SSF52540 536 838 6.09E-89 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 Gene3D G3DSA:3.40.50.300 141 333 5.8E-77 T 11-10-2018 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 SUPERFAMILY SSF52540 149 535 1.79E-101 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 757 836 2.2E-30 T 11-10-2018 IPR019489 Clp ATPase, C-terminal TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 286 298 - T 11-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 SUPERFAMILY SSF81923 4 148 7.72E-34 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 621 639 - T 11-10-2018 IPR028299 ClpA/B, conserved site 2 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 Gene3D G3DSA:3.40.50.300 539 755 3.2E-90 T 11-10-2018 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 7.1E-14 T 11-10-2018 IPR004176 Clp, N-terminal TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 Gene3D G3DSA:1.10.8.60 757 854 2.8E-34 T 11-10-2018 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 Pfam PF07724 AAA domain (Cdc48 subfamily) 586 751 3.2E-55 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 1.8E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 665 683 1.8E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 636 654 1.8E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 698 712 1.8E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 Gene3D G3DSA:3.40.50.300 334 534 1.4E-79 T 11-10-2018 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 SMART SM00382 587 729 1.2E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 SMART SM00382 190 334 2.9E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 SMART SM01086 757 846 3.3E-43 T 11-10-2018 IPR019489 Clp ATPase, C-terminal TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 Gene3D G3DSA:1.10.1780.10 1 140 1.3E-34 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TO73_1940 9813e3d4cf631c7db232b89052b4abef 854 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 846 0.0 T 11-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 TO73_0985 06673a09d0bddcc4931b51f9a504f4f9 327 Gene3D G3DSA:1.20.120.920 82 326 9.5E-71 T 11-10-2018 TO73_0985 06673a09d0bddcc4931b51f9a504f4f9 327 Pfam PF01867 CRISPR associated protein Cas1 5 283 2.0E-88 T 11-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TO73_0985 06673a09d0bddcc4931b51f9a504f4f9 327 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 5 323 4.2E-99 T 11-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TO73_0985 06673a09d0bddcc4931b51f9a504f4f9 327 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 4 326 1.0E-124 T 11-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 TO73_0985 06673a09d0bddcc4931b51f9a504f4f9 327 Gene3D G3DSA:3.100.10.20 2 81 1.7E-29 T 11-10-2018 TO73_0985 06673a09d0bddcc4931b51f9a504f4f9 327 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 313 27.166 T 11-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TO73_0486 3ef3f4bae838bc15b5dcab74683ab099 600 Gene3D G3DSA:3.40.50.1820 342 600 1.1E-63 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0486 3ef3f4bae838bc15b5dcab74683ab099 600 SUPERFAMILY SSF53474 353 600 6.54E-61 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0486 3ef3f4bae838bc15b5dcab74683ab099 600 Pfam PF00326 Prolyl oligopeptidase family 395 599 5.4E-44 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TO73_0486 3ef3f4bae838bc15b5dcab74683ab099 600 SUPERFAMILY SSF82171 67 301 2.49E-11 T 11-10-2018 TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 SUPERFAMILY SSF52518 6 323 3.75E-113 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 TIGRFAM TIGR00232 tktlase_bact: transketolase 11 648 3.1E-270 T 11-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 10 336 1.3E-147 T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 Gene3D G3DSA:3.40.50.920 532 652 4.6E-43 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 SUPERFAMILY SSF52922 527 651 1.23E-43 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 Gene3D G3DSA:3.40.50.970 1 327 1.9E-121 T 11-10-2018 TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 Pfam PF02780 Transketolase, C-terminal domain 533 643 2.2E-10 T 11-10-2018 IPR033248 Transketolase, C-terminal domain TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 Gene3D G3DSA:3.40.50.970 329 530 1.7E-79 T 11-10-2018 TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 SMART SM00861 349 520 6.3E-69 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 Pfam PF02779 Transketolase, pyrimidine binding domain 348 519 1.0E-46 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_1893 2b91ba7e51b8dd97ce169bc646f945fe 652 SUPERFAMILY SSF52518 344 521 3.24E-67 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_1251 01e15fc936e2adc80d8ea79f0d5d547a 390 Pfam PF00067 Cytochrome P450 204 365 5.8E-36 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TO73_1251 01e15fc936e2adc80d8ea79f0d5d547a 390 PRINTS PR00385 P450 superfamily signature 327 336 5.7E-12 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TO73_1251 01e15fc936e2adc80d8ea79f0d5d547a 390 PRINTS PR00385 P450 superfamily signature 256 267 5.7E-12 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TO73_1251 01e15fc936e2adc80d8ea79f0d5d547a 390 PRINTS PR00385 P450 superfamily signature 221 238 5.7E-12 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TO73_1251 01e15fc936e2adc80d8ea79f0d5d547a 390 PRINTS PR00385 P450 superfamily signature 336 347 5.7E-12 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TO73_1251 01e15fc936e2adc80d8ea79f0d5d547a 390 SUPERFAMILY SSF48264 11 385 2.36E-72 T 11-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TO73_1251 01e15fc936e2adc80d8ea79f0d5d547a 390 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 329 338 - T 11-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TO73_1251 01e15fc936e2adc80d8ea79f0d5d547a 390 Gene3D G3DSA:1.10.630.10 1 386 2.4E-146 T 11-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TO73_1372 609fbbfcf6a95d68a2d263b76f93d982 406 SUPERFAMILY SSF63411 4 203 2.62E-49 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TO73_1372 609fbbfcf6a95d68a2d263b76f93d982 406 SUPERFAMILY SSF63411 231 402 2.07E-28 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TO73_1372 609fbbfcf6a95d68a2d263b76f93d982 406 Gene3D G3DSA:3.30.830.10 1 212 3.0E-75 T 11-10-2018 TO73_1372 609fbbfcf6a95d68a2d263b76f93d982 406 Gene3D G3DSA:3.30.830.10 225 406 2.2E-41 T 11-10-2018 TO73_1372 609fbbfcf6a95d68a2d263b76f93d982 406 Pfam PF00675 Insulinase (Peptidase family M16) 12 158 5.1E-26 T 11-10-2018 IPR011765 Peptidase M16, N-terminal TO73_1372 609fbbfcf6a95d68a2d263b76f93d982 406 Pfam PF05193 Peptidase M16 inactive domain 165 336 5.8E-20 T 11-10-2018 IPR007863 Peptidase M16, C-terminal TO73_1406 4d9080f84a29add31237f7f91a950acb 825 Gene3D G3DSA:3.10.20.310 304 377 4.2E-8 T 11-10-2018 TO73_1406 4d9080f84a29add31237f7f91a950acb 825 Gene3D G3DSA:3.10.20.310 165 241 2.7E-9 T 11-10-2018 TO73_1406 4d9080f84a29add31237f7f91a950acb 825 Pfam PF01103 Surface antigen 481 824 3.1E-21 T 11-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 TO73_1406 4d9080f84a29add31237f7f91a950acb 825 Gene3D G3DSA:3.10.20.310 378 456 3.0E-9 T 11-10-2018 TO73_1406 4d9080f84a29add31237f7f91a950acb 825 Pfam PF08479 POTRA domain, ShlB-type 170 240 7.7E-7 T 11-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type TO73_1406 4d9080f84a29add31237f7f91a950acb 825 Gene3D G3DSA:2.40.160.50 457 825 6.5E-22 T 11-10-2018 TO73_1406 4d9080f84a29add31237f7f91a950acb 825 Pfam PF07244 Surface antigen variable number repeat 308 365 5.1E-7 T 11-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TO73_1406 4d9080f84a29add31237f7f91a950acb 825 Pfam PF07244 Surface antigen variable number repeat 89 166 4.5E-7 T 11-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TO73_0593 65801122ed1f159b1ae42d93a0f0ed8f 600 SUPERFAMILY SSF90123 17 341 4.58E-84 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TO73_0593 65801122ed1f159b1ae42d93a0f0ed8f 600 SUPERFAMILY SSF52540 343 598 2.02E-83 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0593 65801122ed1f159b1ae42d93a0f0ed8f 600 Pfam PF00664 ABC transporter transmembrane region 30 308 5.8E-58 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TO73_0593 65801122ed1f159b1ae42d93a0f0ed8f 600 Pfam PF00005 ABC transporter 377 527 1.2E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0593 65801122ed1f159b1ae42d93a0f0ed8f 600 Gene3D G3DSA:3.40.50.300 345 600 1.2E-82 T 11-10-2018 TO73_0593 65801122ed1f159b1ae42d93a0f0ed8f 600 Gene3D G3DSA:1.20.1560.10 3 341 1.2E-97 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TO73_0593 65801122ed1f159b1ae42d93a0f0ed8f 600 SMART SM00382 386 573 5.0E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0603 5cc14a5839c054f109807227d5d4bef6 389 Gene3D G3DSA:3.40.50.2300 31 354 1.2E-90 T 11-10-2018 TO73_0603 5cc14a5839c054f109807227d5d4bef6 389 Pfam PF13458 Periplasmic binding protein 24 370 5.9E-53 T 11-10-2018 IPR028081 Leucine-binding protein domain TO73_0603 5cc14a5839c054f109807227d5d4bef6 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 24 40 2.8E-5 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TO73_0603 5cc14a5839c054f109807227d5d4bef6 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 65 83 2.8E-5 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TO73_0603 5cc14a5839c054f109807227d5d4bef6 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 46 62 2.8E-5 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TO73_0603 5cc14a5839c054f109807227d5d4bef6 389 SUPERFAMILY SSF53822 23 373 9.76E-81 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_0603 5cc14a5839c054f109807227d5d4bef6 389 Gene3D G3DSA:3.40.50.2300 143 273 1.2E-90 T 11-10-2018 TO73_2318 97f35bfe9041c523945de7a1a0dbe395 270 Gene3D G3DSA:2.170.120.30 29 112 2.7E-9 T 11-10-2018 TO73_0846 716b42e5bc0fa053cdca944387ccad43 152 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.539 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 TO73_0846 716b42e5bc0fa053cdca944387ccad43 152 Gene3D G3DSA:3.50.80.10 1 148 3.5E-58 T 11-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TO73_0846 716b42e5bc0fa053cdca944387ccad43 152 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 7.7E-57 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 TO73_0846 716b42e5bc0fa053cdca944387ccad43 152 SUPERFAMILY SSF69500 1 145 3.27E-57 T 11-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TO73_0846 716b42e5bc0fa053cdca944387ccad43 152 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 6.8E-55 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 TO73_0442 8162c9fb7b3e26cc0232070e8350a5a2 227 PIRSF PIRSF001586 1 227 9.7E-88 T 11-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_0442 8162c9fb7b3e26cc0232070e8350a5a2 227 Gene3D G3DSA:3.40.50.880 1 226 9.4E-71 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0442 8162c9fb7b3e26cc0232070e8350a5a2 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 224 2.4E-96 T 11-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_0442 8162c9fb7b3e26cc0232070e8350a5a2 227 SUPERFAMILY SSF52317 1 223 2.7E-74 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0442 8162c9fb7b3e26cc0232070e8350a5a2 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 209 3.5E-47 T 11-10-2018 TO73_0442 8162c9fb7b3e26cc0232070e8350a5a2 227 SMART SM01211 1 225 4.1E-132 T 11-10-2018 TO73_0442 8162c9fb7b3e26cc0232070e8350a5a2 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 223 45.737 T 11-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_1343 aa0654235922c4bf74dbe7539723960e 561 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 8.9E-57 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TO73_1343 aa0654235922c4bf74dbe7539723960e 561 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 551 4.3E-241 T 11-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TO73_1343 aa0654235922c4bf74dbe7539723960e 561 SUPERFAMILY SSF52518 1 169 2.19E-62 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_1343 aa0654235922c4bf74dbe7539723960e 561 SUPERFAMILY SSF52518 358 553 7.33E-69 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_1343 aa0654235922c4bf74dbe7539723960e 561 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 323 8.3E-48 T 11-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TO73_1343 aa0654235922c4bf74dbe7539723960e 561 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 416 435 - T 11-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TO73_1343 aa0654235922c4bf74dbe7539723960e 561 Gene3D G3DSA:3.40.50.1220 185 347 4.9E-64 T 11-10-2018 TO73_1343 aa0654235922c4bf74dbe7539723960e 561 Gene3D G3DSA:3.40.50.970 1 173 5.2E-69 T 11-10-2018 TO73_1343 aa0654235922c4bf74dbe7539723960e 561 SUPERFAMILY SSF52467 183 349 4.62E-62 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TO73_1343 aa0654235922c4bf74dbe7539723960e 561 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 527 7.3E-52 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TO73_1343 aa0654235922c4bf74dbe7539723960e 561 Gene3D G3DSA:3.40.50.970 352 559 3.8E-70 T 11-10-2018 TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 SMART SM00116 219 268 0.46 T 11-10-2018 IPR000644 CBS domain TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 SMART SM00116 283 331 1.6 T 11-10-2018 IPR000644 CBS domain TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 Pfam PF00571 CBS domain 210 266 2.1E-7 T 11-10-2018 IPR000644 CBS domain TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 Pfam PF00571 CBS domain 280 331 6.6E-7 T 11-10-2018 IPR000644 CBS domain TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 SMART SM01091 347 425 8.5E-32 T 11-10-2018 IPR005170 Transporter-associated domain TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 SUPERFAMILY SSF56176 346 427 2.02E-24 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 SUPERFAMILY SSF54631 205 344 2.78E-36 T 11-10-2018 TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 Gene3D G3DSA:3.30.465.10 339 425 5.1E-26 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 Pfam PF03471 Transporter associated domain 348 423 1.7E-25 T 11-10-2018 IPR005170 Transporter-associated domain TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 Pfam PF01595 Domain of unknown function DUF21 21 195 7.3E-46 T 11-10-2018 IPR002550 CNNM, transmembrane domain TO73_0677 5bc0eac347f7dab1bd577c06c818f2bb 430 Gene3D G3DSA:3.10.580.10 189 338 1.4E-58 T 11-10-2018 TO73_1987 a62efeb4725de851a33dee14544d2a30 277 ProSitePatterns PS00018 EF-hand calcium-binding domain. 250 262 - T 11-10-2018 IPR018247 EF-Hand 1, calcium-binding site TO73_1987 a62efeb4725de851a33dee14544d2a30 277 Gene3D G3DSA:2.60.40.10 20 109 5.2E-11 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_1690 d124cc969b139d976fe226139313d9e0 398 SUPERFAMILY SSF48013 6 139 1.06E-22 T 11-10-2018 IPR035926 NusB-like superfamily TO73_1690 d124cc969b139d976fe226139313d9e0 398 Gene3D G3DSA:1.10.940.10 2 132 3.4E-23 T 11-10-2018 IPR035926 NusB-like superfamily TO73_1690 d124cc969b139d976fe226139313d9e0 398 Pfam PF01029 NusB family 5 122 1.8E-16 T 11-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TO73_1690 d124cc969b139d976fe226139313d9e0 398 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 328 344 1.2E-14 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TO73_1690 d124cc969b139d976fe226139313d9e0 398 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 376 393 1.2E-14 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TO73_1690 d124cc969b139d976fe226139313d9e0 398 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 278 290 1.2E-14 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TO73_1690 d124cc969b139d976fe226139313d9e0 398 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 218 228 1.2E-14 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TO73_1690 d124cc969b139d976fe226139313d9e0 398 Pfam PF01189 16S rRNA methyltransferase RsmB/F 207 391 6.1E-35 T 11-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TO73_1690 d124cc969b139d976fe226139313d9e0 398 SUPERFAMILY SSF53335 128 394 5.17E-46 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1690 d124cc969b139d976fe226139313d9e0 398 Gene3D G3DSA:3.40.50.150 198 394 6.1E-45 T 11-10-2018 TO73_1887 239152d5c5c2e7022e40514189345554 722 SUPERFAMILY SSF48452 558 710 8.43E-25 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1887 239152d5c5c2e7022e40514189345554 722 SUPERFAMILY SSF55874 156 310 2.62E-45 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1887 239152d5c5c2e7022e40514189345554 722 PRINTS PR00344 Bacterial sensor protein C-terminal signature 256 266 3.5E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1887 239152d5c5c2e7022e40514189345554 722 PRINTS PR00344 Bacterial sensor protein C-terminal signature 238 252 3.5E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1887 239152d5c5c2e7022e40514189345554 722 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 308 3.5E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1887 239152d5c5c2e7022e40514189345554 722 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 289 3.5E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1887 239152d5c5c2e7022e40514189345554 722 Pfam PF14559 Tetratricopeptide repeat 665 715 1.0E-5 T 11-10-2018 TO73_1887 239152d5c5c2e7022e40514189345554 722 Pfam PF14559 Tetratricopeptide repeat 621 664 8.8E-8 T 11-10-2018 TO73_1887 239152d5c5c2e7022e40514189345554 722 Gene3D G3DSA:3.30.565.10 154 308 6.2E-57 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1887 239152d5c5c2e7022e40514189345554 722 Gene3D G3DSA:1.10.287.130 99 153 6.2E-57 T 11-10-2018 TO73_1887 239152d5c5c2e7022e40514189345554 722 SUPERFAMILY SSF47384 77 155 1.2E-9 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TO73_1887 239152d5c5c2e7022e40514189345554 722 Pfam PF00512 His Kinase A (phospho-acceptor) domain 93 155 1.4E-10 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_1887 239152d5c5c2e7022e40514189345554 722 SMART SM00388 90 156 1.5E-9 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_1887 239152d5c5c2e7022e40514189345554 722 Gene3D G3DSA:1.25.40.10 533 713 1.4E-32 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1887 239152d5c5c2e7022e40514189345554 722 SMART SM00387 201 311 6.4E-40 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1887 239152d5c5c2e7022e40514189345554 722 SMART SM00028 612 643 47.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1887 239152d5c5c2e7022e40514189345554 722 SMART SM00028 577 610 0.019 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1887 239152d5c5c2e7022e40514189345554 722 SMART SM00028 678 711 26.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1887 239152d5c5c2e7022e40514189345554 722 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 201 309 9.1E-25 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1887 239152d5c5c2e7022e40514189345554 722 Pfam PF13432 Tetratricopeptide repeat 559 605 2.6E-4 T 11-10-2018 TO73_1133 825f73289874fef76b618c3f7bfe252d 173 Pfam PF05685 Putative restriction endonuclease 20 165 2.2E-23 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1133 825f73289874fef76b618c3f7bfe252d 173 SUPERFAMILY SSF52980 4 157 1.29E-14 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1133 825f73289874fef76b618c3f7bfe252d 173 Gene3D G3DSA:3.90.1570.10 2 161 1.3E-10 T 11-10-2018 TO73_0477 77d0cd063eae1d7e08cc4aada019068c 175 Gene3D G3DSA:3.40.50.2020 1 175 7.7E-43 T 11-10-2018 TO73_0477 77d0cd063eae1d7e08cc4aada019068c 175 SUPERFAMILY SSF53271 8 163 5.0E-20 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_0237 e744ba4f953c9e3cc611d8c84555e954 73 Pfam PF00313 'Cold-shock' DNA-binding domain 3 67 8.5E-27 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TO73_0237 e744ba4f953c9e3cc611d8c84555e954 73 PIRSF PIRSF002599 1 73 1.1E-24 T 11-10-2018 IPR012156 Cold shock, CspA GO:0003676 TO73_0237 e744ba4f953c9e3cc611d8c84555e954 73 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 11-10-2018 IPR019844 Cold-shock conserved site TO73_0237 e744ba4f953c9e3cc611d8c84555e954 73 Gene3D G3DSA:2.40.50.140 1 73 1.0E-32 T 11-10-2018 TO73_0237 e744ba4f953c9e3cc611d8c84555e954 73 SMART SM00357 3 68 1.1E-29 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 TO73_0237 e744ba4f953c9e3cc611d8c84555e954 73 SUPERFAMILY SSF50249 1 69 1.71E-23 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_0237 e744ba4f953c9e3cc611d8c84555e954 73 PRINTS PR00050 Cold shock protein signature 24 33 3.9E-16 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TO73_0237 e744ba4f953c9e3cc611d8c84555e954 73 PRINTS PR00050 Cold shock protein signature 4 19 3.9E-16 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TO73_0237 e744ba4f953c9e3cc611d8c84555e954 73 PRINTS PR00050 Cold shock protein signature 39 57 3.9E-16 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TO73_1640 3b2f45fffb898b0e790d068a9ae106c8 260 SMART SM01021 15 256 5.2E-49 T 11-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 TO73_1640 3b2f45fffb898b0e790d068a9ae106c8 260 SUPERFAMILY SSF81321 15 246 8.55E-47 T 11-10-2018 TO73_1640 3b2f45fffb898b0e790d068a9ae106c8 260 PRINTS PR00251 Bacterial opsin signature 34 54 2.4E-12 T 11-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 TO73_1640 3b2f45fffb898b0e790d068a9ae106c8 260 PRINTS PR00251 Bacterial opsin signature 223 241 2.4E-12 T 11-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 TO73_1640 3b2f45fffb898b0e790d068a9ae106c8 260 PRINTS PR00251 Bacterial opsin signature 190 208 2.4E-12 T 11-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 TO73_1640 3b2f45fffb898b0e790d068a9ae106c8 260 PRINTS PR00251 Bacterial opsin signature 90 111 2.4E-12 T 11-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 TO73_1640 3b2f45fffb898b0e790d068a9ae106c8 260 Pfam PF01036 Bacteriorhodopsin-like protein 18 248 6.1E-21 T 11-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 TO73_1640 3b2f45fffb898b0e790d068a9ae106c8 260 Gene3D G3DSA:1.20.1070.10 1 252 4.0E-98 T 11-10-2018 TO73_1640 3b2f45fffb898b0e790d068a9ae106c8 260 ProSitePatterns PS00950 Bacterial rhodopsins signature 1. 92 104 - T 11-10-2018 IPR018229 Rhodopsin, retinal binding site GO:0005216|GO:0006811|GO:0016020 TO73_2109 d617f2d1865c4b19d9a45129882f3b1e 139 Gene3D G3DSA:3.10.129.10 7 139 1.1E-43 T 11-10-2018 TO73_2109 d617f2d1865c4b19d9a45129882f3b1e 139 SUPERFAMILY SSF54637 8 134 3.59E-39 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_2109 d617f2d1865c4b19d9a45129882f3b1e 139 Pfam PF13279 Thioesterase-like superfamily 18 130 3.1E-18 T 11-10-2018 TO73_1412 81ff56a3ab4fcbe4e10b94752fc6106f 147 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 24 5.5E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1412 81ff56a3ab4fcbe4e10b94752fc6106f 147 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 23 7.3E-5 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1412 81ff56a3ab4fcbe4e10b94752fc6106f 147 Gene3D G3DSA:3.30.700.10 6 126 2.1E-8 T 11-10-2018 TO73_1412 81ff56a3ab4fcbe4e10b94752fc6106f 147 SUPERFAMILY SSF54523 6 122 2.12E-13 T 11-10-2018 TO73_1412 81ff56a3ab4fcbe4e10b94752fc6106f 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 160 208 - T 11-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 SUPERFAMILY SSF81464 26 108 1.08E-17 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 SUPERFAMILY SSF49503 112 262 3.95E-48 T 11-10-2018 IPR008972 Cupredoxin TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 Gene3D G3DSA:2.60.40.2600 112 337 4.2E-89 T 11-10-2018 TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 Pfam PF00034 Cytochrome c 237 325 1.6E-10 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 139 211 9.9E-17 T 11-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 33 98 8.4E-9 T 11-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 28 225 2.1E-73 T 11-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 SUPERFAMILY SSF46626 237 326 1.05E-19 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_2237 89764f0c36ee04fb56e2ebec4672ce54 337 Gene3D G3DSA:1.10.287.90 19 111 1.3E-35 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 627 9.3E-183 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 Gene3D G3DSA:1.10.730.10 631 821 3.3E-62 T 11-10-2018 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 Gene3D G3DSA:3.90.740.10 196 390 2.6E-265 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 Gene3D G3DSA:3.40.50.620 14 617 2.6E-265 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 SUPERFAMILY SSF50677 203 380 1.05E-46 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 SUPERFAMILY SSF52374 7 640 3.67E-143 T 11-10-2018 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 SUPERFAMILY SSF47323 645 889 2.62E-55 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 384 399 4.4E-28 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 510 523 4.4E-28 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 4.4E-28 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 225 248 4.4E-28 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 550 559 4.4E-28 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 Pfam PF08264 Anticodon-binding domain of tRNA 677 828 3.2E-31 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1038 14.113 T 11-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1654 514b0334e4a935355cabcb6483b622f1 1047 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 8 834 8.4E-291 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TO73_0484 9d8497163ee46f5e267bd6a1f1744788 201 Pfam PF02223 Thymidylate kinase 8 192 4.1E-47 T 11-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TO73_0484 9d8497163ee46f5e267bd6a1f1744788 201 Gene3D G3DSA:3.40.50.300 1 200 2.0E-65 T 11-10-2018 TO73_0484 9d8497163ee46f5e267bd6a1f1744788 201 SUPERFAMILY SSF52540 1 197 5.48E-52 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0484 9d8497163ee46f5e267bd6a1f1744788 201 ProSitePatterns PS01331 Thymidylate kinase signature. 91 103 - T 11-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TO73_0484 9d8497163ee46f5e267bd6a1f1744788 201 Hamap MF_00165 Thymidylate kinase [tmk]. 4 200 30.481 T 11-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TO73_0484 9d8497163ee46f5e267bd6a1f1744788 201 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 192 1.0E-49 T 11-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 SUPERFAMILY SSF53671 2 296 1.14E-88 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 4.1E-18 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 249 258 4.1E-18 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 261 284 4.1E-18 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 4.1E-18 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 Gene3D G3DSA:3.40.50.1370 132 275 5.7E-86 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 76 85 5.2E-32 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 131 148 5.2E-32 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 277 291 5.2E-32 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 5.2E-32 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 213 222 5.2E-32 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 253 258 5.2E-32 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 145 3.1E-38 T 11-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 298 39.026 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 Gene3D G3DSA:3.40.50.1370 7 292 5.7E-86 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 294 8.2E-23 T 11-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TO73_1491 d990c2ac72a05be5f0cea2b3963049c4 301 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 296 3.5E-88 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TO73_2242 e13e37817dbd8f67ac03b83a3884a606 395 Gene3D G3DSA:2.130.10.10 283 393 7.3E-9 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TO73_2242 e13e37817dbd8f67ac03b83a3884a606 395 SUPERFAMILY SSF50969 38 386 1.69E-16 T 11-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like TO73_1949 dd2d1ca6c7914de369f453e72dfab355 157 Gene3D G3DSA:3.30.70.1450 84 157 4.5E-15 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TO73_1949 dd2d1ca6c7914de369f453e72dfab355 157 SUPERFAMILY SSF116726 85 156 3.4E-15 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TO73_1949 dd2d1ca6c7914de369f453e72dfab355 157 Pfam PF02080 TrkA-C domain 90 156 1.1E-14 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TO73_1949 dd2d1ca6c7914de369f453e72dfab355 157 PIRSF PIRSF005028 1 157 7.5E-50 T 11-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT TO73_0583 09500fd9a413eef6d97be6ef260ce1ea 140 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 9 125 6.9E-6 T 11-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system TO73_0583 09500fd9a413eef6d97be6ef260ce1ea 140 Gene3D G3DSA:3.30.460.40 2 140 1.1E-15 T 11-10-2018 TO73_0583 09500fd9a413eef6d97be6ef260ce1ea 140 SUPERFAMILY SSF81301 1 140 5.23E-22 T 11-10-2018 TO73_1454 570c32ca21ee8a868588fb695e820323 830 Pfam PF00512 His Kinase A (phospho-acceptor) domain 610 676 2.3E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_1454 570c32ca21ee8a868588fb695e820323 830 SUPERFAMILY SSF55874 677 824 5.24E-32 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1454 570c32ca21ee8a868588fb695e820323 830 SMART SM00387 721 822 6.2E-31 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1454 570c32ca21ee8a868588fb695e820323 830 Gene3D G3DSA:1.20.1730.10 33 451 4.5E-10 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily TO73_1454 570c32ca21ee8a868588fb695e820323 830 Gene3D G3DSA:1.10.287.130 573 674 4.5E-18 T 11-10-2018 TO73_1454 570c32ca21ee8a868588fb695e820323 830 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 721 821 2.1E-16 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1454 570c32ca21ee8a868588fb695e820323 830 Gene3D G3DSA:3.30.565.10 681 822 8.1E-32 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_1454 570c32ca21ee8a868588fb695e820323 830 SMART SM00388 609 676 1.2E-18 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_1454 570c32ca21ee8a868588fb695e820323 830 SUPERFAMILY SSF47384 594 676 1.8E-17 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TO73_1454 570c32ca21ee8a868588fb695e820323 830 PRINTS PR00344 Bacterial sensor protein C-terminal signature 756 770 2.5E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1454 570c32ca21ee8a868588fb695e820323 830 PRINTS PR00344 Bacterial sensor protein C-terminal signature 784 802 2.5E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1454 570c32ca21ee8a868588fb695e820323 830 PRINTS PR00344 Bacterial sensor protein C-terminal signature 774 784 2.5E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_1293 9bf0ca1a373a425e322486fad77b955c 650 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 19 649 1.4E-203 T 11-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TO73_1293 9bf0ca1a373a425e322486fad77b955c 650 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 115 577 1.6E-81 T 11-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 461 5.1E-160 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 Gene3D G3DSA:3.50.50.60 7 330 3.0E-129 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 Gene3D G3DSA:3.50.50.60 144 267 3.0E-129 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 SUPERFAMILY SSF51905 5 334 7.54E-64 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 SUPERFAMILY SSF55424 341 461 1.24E-41 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 Gene3D G3DSA:3.30.390.30 341 464 3.8E-48 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 5.6E-75 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 5.6E-75 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 5.6E-75 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 5.6E-75 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 5.6E-75 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 5.6E-75 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 5.6E-75 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 5.6E-75 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 5.6E-75 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 450 3.3E-35 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 324 2.1E-67 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 41 51 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 7.7E-39 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 7.7E-39 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 7.7E-39 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.7E-39 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 7.7E-39 T 11-10-2018 TO73_0136 1b48da305a6433cc5be6d5b7400d0a0b 464 PIRSF PIRSF000350 1 461 1.4E-94 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TO73_1387 04e322a3ef51fa2c15550eaa57e3ba3b 247 Gene3D G3DSA:3.30.70.1900 106 236 1.2E-34 T 11-10-2018 TO73_1387 04e322a3ef51fa2c15550eaa57e3ba3b 247 Gene3D G3DSA:3.30.70.1890 1 105 4.8E-48 T 11-10-2018 TO73_1387 04e322a3ef51fa2c15550eaa57e3ba3b 247 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 120 232 2.4E-17 T 11-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal TO73_1673 c80aacc442afe6d5f9d83976d9de4e4b 237 Pfam PF01555 DNA methylase 157 218 1.0E-15 T 11-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 TO73_1673 c80aacc442afe6d5f9d83976d9de4e4b 237 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 29 43 2.5E-22 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TO73_1673 c80aacc442afe6d5f9d83976d9de4e4b 237 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 202 222 2.5E-22 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TO73_1673 c80aacc442afe6d5f9d83976d9de4e4b 237 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 160 177 2.5E-22 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TO73_1673 c80aacc442afe6d5f9d83976d9de4e4b 237 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 179 197 2.5E-22 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TO73_1673 c80aacc442afe6d5f9d83976d9de4e4b 237 Gene3D G3DSA:3.40.50.150 5 232 9.5E-34 T 11-10-2018 TO73_1673 c80aacc442afe6d5f9d83976d9de4e4b 237 SUPERFAMILY SSF53335 6 222 3.93E-35 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1673 c80aacc442afe6d5f9d83976d9de4e4b 237 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 33 39 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TO73_1479 9a2e8b22043ef5e2a9ca15724fac94f9 196 Gene3D G3DSA:3.90.870.10 2 195 5.6E-52 T 11-10-2018 TO73_1479 9a2e8b22043ef5e2a9ca15724fac94f9 196 Pfam PF01300 Telomere recombination 14 183 7.0E-42 T 11-10-2018 IPR006070 YrdC-like domain GO:0003725 TO73_1479 9a2e8b22043ef5e2a9ca15724fac94f9 196 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 186 2.1E-38 T 11-10-2018 IPR006070 YrdC-like domain GO:0003725 TO73_1479 9a2e8b22043ef5e2a9ca15724fac94f9 196 SUPERFAMILY SSF55821 8 194 5.8E-44 T 11-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TO73_0220 b2d9782525aee60c403369e50ebfd350 113 SUPERFAMILY SSF81301 7 112 1.24E-32 T 11-10-2018 TO73_0220 b2d9782525aee60c403369e50ebfd350 113 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 13 107 8.7E-32 T 11-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TO73_0220 b2d9782525aee60c403369e50ebfd350 113 Pfam PF02410 Ribosomal silencing factor during starvation 14 107 5.3E-25 T 11-10-2018 TO73_0220 b2d9782525aee60c403369e50ebfd350 113 Gene3D G3DSA:3.30.460.10 1 111 2.1E-34 T 11-10-2018 TO73_0220 b2d9782525aee60c403369e50ebfd350 113 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 108 22.801 T 11-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TO73_1754 0739539cd1045332324b7efe32759438 496 SUPERFAMILY SSF52540 5 226 4.6E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1754 0739539cd1045332324b7efe32759438 496 SUPERFAMILY SSF52540 266 485 2.37E-37 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1754 0739539cd1045332324b7efe32759438 496 Gene3D G3DSA:3.40.50.300 2 238 3.9E-57 T 11-10-2018 TO73_1754 0739539cd1045332324b7efe32759438 496 SMART SM00382 29 217 2.0E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1754 0739539cd1045332324b7efe32759438 496 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1754 0739539cd1045332324b7efe32759438 496 Pfam PF00005 ABC transporter 268 423 7.7E-13 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1754 0739539cd1045332324b7efe32759438 496 Gene3D G3DSA:3.40.50.300 253 493 6.4E-37 T 11-10-2018 TO73_1754 0739539cd1045332324b7efe32759438 496 Pfam PF00005 ABC transporter 21 169 6.6E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1657 19cb4d8a86bad91fd2edeea8567cad4d 163 SUPERFAMILY SSF54106 16 59 8.63E-13 T 11-10-2018 TO73_1657 19cb4d8a86bad91fd2edeea8567cad4d 163 Gene3D G3DSA:2.40.40.10 70 162 5.7E-36 T 11-10-2018 IPR036908 RlpA-like domain superfamily TO73_1657 19cb4d8a86bad91fd2edeea8567cad4d 163 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 13 161 23.282 T 11-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 TO73_1657 19cb4d8a86bad91fd2edeea8567cad4d 163 SUPERFAMILY SSF50685 70 152 4.88E-15 T 11-10-2018 IPR036908 RlpA-like domain superfamily TO73_1657 19cb4d8a86bad91fd2edeea8567cad4d 163 Gene3D G3DSA:3.10.350.10 15 60 8.4E-20 T 11-10-2018 IPR036779 LysM domain superfamily TO73_1657 19cb4d8a86bad91fd2edeea8567cad4d 163 Pfam PF01476 LysM domain 18 59 8.9E-16 T 11-10-2018 IPR018392 LysM domain TO73_1657 19cb4d8a86bad91fd2edeea8567cad4d 163 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 73 162 8.2E-41 T 11-10-2018 IPR012997 Rare lipoprotein A TO73_1657 19cb4d8a86bad91fd2edeea8567cad4d 163 Pfam PF03330 Lytic transglycolase 72 157 7.7E-24 T 11-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain TO73_1657 19cb4d8a86bad91fd2edeea8567cad4d 163 SMART SM00257 17 60 2.2E-16 T 11-10-2018 IPR018392 LysM domain TO73_0831 27f4d3c5eb42f2edfa759f59ac237f6f 384 PIRSF PIRSF000429 1 384 6.8E-121 T 11-10-2018 IPR002155 Thiolase GO:0016747 TO73_0831 27f4d3c5eb42f2edfa759f59ac237f6f 384 SUPERFAMILY SSF53901 262 383 5.21E-39 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0831 27f4d3c5eb42f2edfa759f59ac237f6f 384 Gene3D G3DSA:3.40.47.10 6 267 2.4E-142 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0831 27f4d3c5eb42f2edfa759f59ac237f6f 384 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 382 3.0E-128 T 11-10-2018 IPR002155 Thiolase GO:0016747 TO73_0831 27f4d3c5eb42f2edfa759f59ac237f6f 384 Pfam PF00108 Thiolase, N-terminal domain 5 251 1.3E-65 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TO73_0831 27f4d3c5eb42f2edfa759f59ac237f6f 384 Gene3D G3DSA:3.40.47.10 127 381 2.4E-142 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0831 27f4d3c5eb42f2edfa759f59ac237f6f 384 SUPERFAMILY SSF53901 5 261 1.45E-75 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0831 27f4d3c5eb42f2edfa759f59ac237f6f 384 ProSitePatterns PS00737 Thiolases signature 2. 330 346 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TO73_0831 27f4d3c5eb42f2edfa759f59ac237f6f 384 Pfam PF02803 Thiolase, C-terminal domain 261 383 9.4E-37 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TO73_0927 52a691425eafc76e528b84d7eee26346 738 Pfam PF13432 Tetratricopeptide repeat 368 428 3.8E-6 T 11-10-2018 TO73_0927 52a691425eafc76e528b84d7eee26346 738 SUPERFAMILY SSF48452 365 556 7.06E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0927 52a691425eafc76e528b84d7eee26346 738 SMART SM00028 526 559 5.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0927 52a691425eafc76e528b84d7eee26346 738 SMART SM00028 363 396 6.8 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0927 52a691425eafc76e528b84d7eee26346 738 Gene3D G3DSA:1.10.10.10 678 734 1.2E-5 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0927 52a691425eafc76e528b84d7eee26346 738 SUPERFAMILY SSF52540 32 206 9.63E-7 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0927 52a691425eafc76e528b84d7eee26346 738 Gene3D G3DSA:1.25.40.10 286 446 4.1E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0927 52a691425eafc76e528b84d7eee26346 738 Gene3D G3DSA:1.25.40.10 447 593 1.2E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1868 ec6a1c6557a605d664d6ef1cef83a561 180 Gene3D G3DSA:3.40.50.1010 1 147 8.7E-29 T 11-10-2018 TO73_1868 ec6a1c6557a605d664d6ef1cef83a561 180 Pfam PF01936 NYN domain 2 144 4.1E-23 T 11-10-2018 IPR021139 NYN domain, limkain-b1-type TO73_2072 192aa13e23a92f436f697b6bf2d8bb4a 595 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 5 451 3.0E-117 T 11-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TO73_2072 192aa13e23a92f436f697b6bf2d8bb4a 595 Gene3D G3DSA:3.40.1670.10 335 450 3.0E-23 T 11-10-2018 TO73_2072 192aa13e23a92f436f697b6bf2d8bb4a 595 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 8 443 9.2E-188 T 11-10-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 TO73_2072 192aa13e23a92f436f697b6bf2d8bb4a 595 SUPERFAMILY SSF143968 484 595 6.54E-17 T 11-10-2018 TO73_2072 192aa13e23a92f436f697b6bf2d8bb4a 595 SUPERFAMILY SSF143968 321 476 2.62E-34 T 11-10-2018 TO73_2072 192aa13e23a92f436f697b6bf2d8bb4a 595 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 9 426 1.3E-150 T 11-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TO73_2072 192aa13e23a92f436f697b6bf2d8bb4a 595 SUPERFAMILY SSF50475 2 320 6.28E-110 T 11-10-2018 TO73_0377 d98f7808a9923c0cb0e4f216bd2a0028 213 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 30 206 6.9E-63 T 11-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0377 d98f7808a9923c0cb0e4f216bd2a0028 213 SUPERFAMILY SSF52166 25 209 1.96E-63 T 11-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0377 d98f7808a9923c0cb0e4f216bd2a0028 213 Gene3D G3DSA:3.40.1370.10 5 213 4.2E-72 T 11-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0377 d98f7808a9923c0cb0e4f216bd2a0028 213 Pfam PF00573 Ribosomal protein L4/L1 family 30 208 1.4E-56 T 11-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TO73_0377 d98f7808a9923c0cb0e4f216bd2a0028 213 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 13 210 28.6 T 11-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0730 a73d0fdb2546079265941f01527fda87 150 SMART SM00116 99 147 3.5E-8 T 11-10-2018 IPR000644 CBS domain TO73_0730 a73d0fdb2546079265941f01527fda87 150 SMART SM00116 11 59 8.4E-14 T 11-10-2018 IPR000644 CBS domain TO73_0730 a73d0fdb2546079265941f01527fda87 150 Pfam PF00571 CBS domain 4 57 5.3E-15 T 11-10-2018 IPR000644 CBS domain TO73_0730 a73d0fdb2546079265941f01527fda87 150 Pfam PF00571 CBS domain 92 144 1.4E-14 T 11-10-2018 IPR000644 CBS domain TO73_0730 a73d0fdb2546079265941f01527fda87 150 SUPERFAMILY SSF54631 2 146 7.55E-38 T 11-10-2018 TO73_0730 a73d0fdb2546079265941f01527fda87 150 Gene3D G3DSA:3.10.580.10 1 149 7.1E-41 T 11-10-2018 TO73_0612 fd98ea52b38593c94d6606b316576066 404 PRINTS PR00834 HtrA/DegQ protease family signature 207 224 8.1E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_0612 fd98ea52b38593c94d6606b316576066 404 PRINTS PR00834 HtrA/DegQ protease family signature 126 146 8.1E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_0612 fd98ea52b38593c94d6606b316576066 404 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 8.1E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_0612 fd98ea52b38593c94d6606b316576066 404 PRINTS PR00834 HtrA/DegQ protease family signature 104 116 8.1E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_0612 fd98ea52b38593c94d6606b316576066 404 PRINTS PR00834 HtrA/DegQ protease family signature 168 192 8.1E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TO73_0612 fd98ea52b38593c94d6606b316576066 404 Pfam PF13180 PDZ domain 288 398 1.3E-13 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_0612 fd98ea52b38593c94d6606b316576066 404 SUPERFAMILY SSF50494 50 275 1.04E-58 T 11-10-2018 IPR009003 Peptidase S1, PA clan TO73_0612 fd98ea52b38593c94d6606b316576066 404 Gene3D G3DSA:2.30.42.10 284 403 4.8E-22 T 11-10-2018 TO73_0612 fd98ea52b38593c94d6606b316576066 404 SUPERFAMILY SSF50156 286 401 7.33E-14 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 TO73_0612 fd98ea52b38593c94d6606b316576066 404 Gene3D G3DSA:2.40.10.120 48 273 2.7E-69 T 11-10-2018 TO73_0612 fd98ea52b38593c94d6606b316576066 404 Pfam PF13365 Trypsin-like peptidase domain 95 236 3.1E-35 T 11-10-2018 TO73_0612 fd98ea52b38593c94d6606b316576066 404 SMART SM00228 287 391 2.5E-6 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_2177 ea7eacd792fbc4e50effcaa1b7448d59 179 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 161 2.4E-27 T 11-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TO73_1120 e09cc0fc45b77ca8b29a3e06507ee2f2 87 Gene3D G3DSA:3.30.1320.10 1 87 7.8E-37 T 11-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1120 e09cc0fc45b77ca8b29a3e06507ee2f2 87 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 77 24.937 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1120 e09cc0fc45b77ca8b29a3e06507ee2f2 87 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 80 4.1E-34 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1120 e09cc0fc45b77ca8b29a3e06507ee2f2 87 Pfam PF00886 Ribosomal protein S16 8 67 5.4E-25 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1120 e09cc0fc45b77ca8b29a3e06507ee2f2 87 SUPERFAMILY SSF54565 1 82 7.59E-33 T 11-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 Hamap MF_00303 Trigger factor [tig]. 1 399 15.833 T 11-10-2018 IPR005215 Trigger factor GO:0015031 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 Gene3D G3DSA:3.10.50.40 149 225 8.7E-43 T 11-10-2018 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 Pfam PF05697 Bacterial trigger factor protein (TF) 9 143 5.8E-34 T 11-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 SUPERFAMILY SSF54534 131 226 1.49E-7 T 11-10-2018 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 PIRSF PIRSF003095 3 403 1.6E-79 T 11-10-2018 IPR005215 Trigger factor GO:0015031 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 SUPERFAMILY SSF102735 6 126 1.26E-28 T 11-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 239 398 2.5E-31 T 11-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 Gene3D G3DSA:1.10.3120.10 113 401 8.7E-43 T 11-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 SUPERFAMILY SSF109998 227 398 5.76E-31 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 Gene3D G3DSA:3.30.70.1050 1 112 7.0E-31 T 11-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TO73_1138 f9546a65b5b5c1a75e90bc1a5da35ccf 403 TIGRFAM TIGR00115 tig: trigger factor 12 398 8.2E-90 T 11-10-2018 IPR005215 Trigger factor GO:0015031 TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 Gene3D G3DSA:3.40.140.10 368 508 1.1E-33 T 11-10-2018 TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 422 454 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 197 9.7E-44 T 11-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 Pfam PF01171 PP-loop family 21 192 1.1E-41 T 11-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 Gene3D G3DSA:3.40.50.620 10 226 3.7E-58 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 373 463 1.0E-16 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 SUPERFAMILY SSF53927 358 503 2.68E-31 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 SUPERFAMILY SSF52402 15 225 8.82E-50 T 11-10-2018 TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 SUPERFAMILY SSF82829 204 301 2.41E-8 T 11-10-2018 TO73_1825 8d15d3e188b699b763a69e54b1c4169a 509 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 8 285 22.612 T 11-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TO73_0328 2a50b117f0219584df488412e1279cb6 344 Gene3D G3DSA:3.40.190.10 20 302 9.2E-102 T 11-10-2018 TO73_0328 2a50b117f0219584df488412e1279cb6 344 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 17 326 9.2E-93 T 11-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 TO73_0328 2a50b117f0219584df488412e1279cb6 344 SUPERFAMILY SSF53850 17 332 1.33E-59 T 11-10-2018 TO73_0328 2a50b117f0219584df488412e1279cb6 344 Pfam PF13343 Bacterial extracellular solute-binding protein 67 293 2.1E-28 T 11-10-2018 TO73_0328 2a50b117f0219584df488412e1279cb6 344 Gene3D G3DSA:3.40.190.10 118 327 9.2E-102 T 11-10-2018 TO73_0088 47b2b812901fbb0fdff7c9682a4b0b85 191 SUPERFAMILY SSF52507 5 186 7.46E-56 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TO73_0088 47b2b812901fbb0fdff7c9682a4b0b85 191 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 4 186 34.281 T 11-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TO73_0088 47b2b812901fbb0fdff7c9682a4b0b85 191 Pfam PF02441 Flavoprotein 5 163 2.6E-23 T 11-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TO73_0088 47b2b812901fbb0fdff7c9682a4b0b85 191 Gene3D G3DSA:3.40.50.1950 5 190 2.6E-71 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TO73_0088 47b2b812901fbb0fdff7c9682a4b0b85 191 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 5 184 3.0E-57 T 11-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TO73_1151 8f908a3c6fe683b66597aaf444a00c32 192 Gene3D G3DSA:3.40.50.10360 1 192 3.4E-82 T 11-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like TO73_1151 8f908a3c6fe683b66597aaf444a00c32 192 Hamap MF_00800 UPF0340 protein . 1 192 80.807 T 11-10-2018 IPR006340 Protein of unknown function DUF436 TO73_1151 8f908a3c6fe683b66597aaf444a00c32 192 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 9 191 2.0E-76 T 11-10-2018 IPR006340 Protein of unknown function DUF436 TO73_1151 8f908a3c6fe683b66597aaf444a00c32 192 SUPERFAMILY SSF110710 1 189 3.92E-72 T 11-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like TO73_1151 8f908a3c6fe683b66597aaf444a00c32 192 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 7 179 2.4E-57 T 11-10-2018 IPR006340 Protein of unknown function DUF436 TO73_1151 8f908a3c6fe683b66597aaf444a00c32 192 Pfam PF04260 Protein of unknown function (DUF436) 7 179 1.6E-66 T 11-10-2018 IPR006340 Protein of unknown function DUF436 TO73_0165 738a071d76b0f3a282ce282305550b97 543 Gene3D G3DSA:3.10.410.10 429 517 1.7E-29 T 11-10-2018 TO73_0165 738a071d76b0f3a282ce282305550b97 543 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 317 328 - T 11-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TO73_0165 738a071d76b0f3a282ce282305550b97 543 Pfam PF01268 Formate--tetrahydrofolate ligase 5 541 4.4E-223 T 11-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TO73_0165 738a071d76b0f3a282ce282305550b97 543 SUPERFAMILY SSF52540 5 540 4.93E-208 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0165 738a071d76b0f3a282ce282305550b97 543 Gene3D G3DSA:3.40.50.300 5 424 5.7E-177 T 11-10-2018 TO73_0165 738a071d76b0f3a282ce282305550b97 543 Gene3D G3DSA:3.30.1510.10 118 236 5.7E-177 T 11-10-2018 TO73_0165 738a071d76b0f3a282ce282305550b97 543 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 92 102 - T 11-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TO73_0165 738a071d76b0f3a282ce282305550b97 543 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 3 543 44.197 T 11-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TO73_0069 de07d3a19153d9b2c1b6d6c7b874b99d 196 Gene3D G3DSA:3.40.50.850 9 195 8.3E-61 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TO73_0069 de07d3a19153d9b2c1b6d6c7b874b99d 196 SUPERFAMILY SSF52499 12 193 2.49E-62 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TO73_0069 de07d3a19153d9b2c1b6d6c7b874b99d 196 Pfam PF00857 Isochorismatase family 20 189 3.0E-43 T 11-10-2018 IPR000868 Isochorismatase-like GO:0003824 TO73_0983 bb05f7932ee2af6981544c0132604f93 749 Gene3D G3DSA:3.40.50.300 448 582 5.3E-9 T 11-10-2018 TO73_0983 bb05f7932ee2af6981544c0132604f93 749 SMART SM00382 257 441 0.0028 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0983 bb05f7932ee2af6981544c0132604f93 749 Gene3D G3DSA:3.40.50.300 246 439 2.4E-14 T 11-10-2018 TO73_0983 bb05f7932ee2af6981544c0132604f93 749 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 13 202 5.2E-22 T 11-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain TO73_0983 bb05f7932ee2af6981544c0132604f93 749 Pfam PF00270 DEAD/DEAH box helicase 261 428 2.5E-8 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TO73_0983 bb05f7932ee2af6981544c0132604f93 749 SUPERFAMILY SSF52540 261 574 1.21E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0983 bb05f7932ee2af6981544c0132604f93 749 SMART SM00487 237 462 1.3E-4 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_0983 bb05f7932ee2af6981544c0132604f93 749 Gene3D G3DSA:1.10.3210.30 1 118 8.6E-16 T 11-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily TO73_2382 cdec5985fe86df987489188599d87197 262 Gene3D G3DSA:3.30.950.10 106 220 8.9E-40 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TO73_2382 cdec5985fe86df987489188599d87197 262 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 3 217 1.8E-68 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TO73_2382 cdec5985fe86df987489188599d87197 262 Gene3D G3DSA:3.40.1010.10 1 105 9.1E-33 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TO73_2382 cdec5985fe86df987489188599d87197 262 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 198 5.2E-31 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TO73_2382 cdec5985fe86df987489188599d87197 262 SUPERFAMILY SSF53790 3 213 1.31E-73 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TO73_2382 cdec5985fe86df987489188599d87197 262 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 2 215 34.997 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TO73_2382 cdec5985fe86df987489188599d87197 262 PIRSF PIRSF005917 1 262 1.7E-89 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TO73_0287 afb758e7ddbc2d279d1251e4721656d7 66 SUPERFAMILY SSF55008 2 64 1.57E-20 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TO73_0287 afb758e7ddbc2d279d1251e4721656d7 66 ProSitePatterns PS01047 Heavy-metal-associated domain. 6 35 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TO73_0287 afb758e7ddbc2d279d1251e4721656d7 66 Pfam PF00403 Heavy-metal-associated domain 4 60 4.8E-18 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TO73_0287 afb758e7ddbc2d279d1251e4721656d7 66 Gene3D G3DSA:3.30.70.100 1 66 3.6E-28 T 11-10-2018 TO73_1095 ee51aa6dbfb299ef325d5243dda39cf5 331 Pfam PF02780 Transketolase, C-terminal domain 199 321 3.8E-37 T 11-10-2018 IPR033248 Transketolase, C-terminal domain TO73_1095 ee51aa6dbfb299ef325d5243dda39cf5 331 Gene3D G3DSA:3.40.50.920 198 331 4.6E-45 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_1095 ee51aa6dbfb299ef325d5243dda39cf5 331 SMART SM00861 9 184 7.2E-65 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_1095 ee51aa6dbfb299ef325d5243dda39cf5 331 SUPERFAMILY SSF52922 194 330 3.01E-38 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TO73_1095 ee51aa6dbfb299ef325d5243dda39cf5 331 Gene3D G3DSA:3.40.50.970 7 197 4.6E-81 T 11-10-2018 TO73_1095 ee51aa6dbfb299ef325d5243dda39cf5 331 Pfam PF02779 Transketolase, pyrimidine binding domain 10 183 6.4E-43 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TO73_1095 ee51aa6dbfb299ef325d5243dda39cf5 331 SUPERFAMILY SSF52518 6 208 3.8E-68 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_0862 451e929d94a51e868fec36ac0ad08623 363 SUPERFAMILY SSF111249 2 362 4.45E-154 T 11-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TO73_0862 451e929d94a51e868fec36ac0ad08623 363 PIRSF PIRSF015647 1 363 5.0E-165 T 11-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TO73_0862 451e929d94a51e868fec36ac0ad08623 363 Pfam PF01950 Fructose-1,6-bisphosphatase 2 362 1.1E-159 T 11-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TO73_0862 451e929d94a51e868fec36ac0ad08623 363 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 363 57.7 T 11-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TO73_0862 451e929d94a51e868fec36ac0ad08623 363 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 2 362 0.0 T 11-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 216 305 2.5E-16 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 Pfam PF01926 50S ribosome-binding GTPase 220 306 6.8E-19 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 Gene3D G3DSA:3.30.1360.120 1 124 3.6E-44 T 11-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 432 30.603 T 11-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 309 1.0E-86 T 11-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 124 1.6E-37 T 11-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 Gene3D G3DSA:1.20.120.430 125 432 6.3E-81 T 11-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 287 305 2.7E-6 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 220 240 2.7E-6 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 SUPERFAMILY SSF52540 76 358 2.87E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 Pfam PF12631 MnmE helical domain 127 429 2.5E-41 T 11-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 TO73_1092 0224aa000c8ce4c61050061568d5d7bd 432 Gene3D G3DSA:3.40.50.300 218 365 6.3E-81 T 11-10-2018 TO73_2213 19f29f48a6e60aafa9506cddcc3978a4 343 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 334 2.0E-66 T 11-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TO73_2213 19f29f48a6e60aafa9506cddcc3978a4 343 Gene3D G3DSA:1.20.1050.90 116 288 3.3E-85 T 11-10-2018 TO73_2213 19f29f48a6e60aafa9506cddcc3978a4 343 Gene3D G3DSA:3.40.50.300 9 320 3.3E-85 T 11-10-2018 TO73_2213 19f29f48a6e60aafa9506cddcc3978a4 343 SUPERFAMILY SSF52540 1 314 1.49E-33 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2213 19f29f48a6e60aafa9506cddcc3978a4 343 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 343 69.602 T 11-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 Pfam PF14698 Argininosuccinate lyase C-terminal 367 434 3.7E-22 T 11-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 Pfam PF00206 Lyase 8 304 7.1E-76 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal TO73_0160 afc550214b8425cdc7186355d9b6408a 462 Gene3D G3DSA:1.20.200.10 109 451 2.1E-155 T 11-10-2018 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 Gene3D G3DSA:1.10.40.30 368 438 2.1E-155 T 11-10-2018 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 Gene3D G3DSA:1.10.275.50 1 108 9.8E-41 T 11-10-2018 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 TIGRFAM TIGR00838 argH: argininosuccinate lyase 5 459 1.2E-180 T 11-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 457 43.485 T 11-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 3.8E-24 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 3.8E-24 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 3.8E-24 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 3.8E-24 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0160 afc550214b8425cdc7186355d9b6408a 462 SUPERFAMILY SSF48557 8 457 5.81E-148 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 6.1E-61 T 11-10-2018 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00145 Argininosuccinate lyase family signature 314 333 6.1E-61 T 11-10-2018 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 6.1E-61 T 11-10-2018 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 6.1E-61 T 11-10-2018 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 6.1E-61 T 11-10-2018 TO73_0160 afc550214b8425cdc7186355d9b6408a 462 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 6.1E-61 T 11-10-2018 TO73_0990 3b980e66aeaa9303b78ce35d778882e3 151 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 12 151 7.9E-49 T 11-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit TO73_0990 3b980e66aeaa9303b78ce35d778882e3 151 SUPERFAMILY SSF117916 5 94 7.85E-20 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TO73_0990 3b980e66aeaa9303b78ce35d778882e3 151 Gene3D G3DSA:3.30.300.130 1 95 4.8E-24 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TO73_0990 3b980e66aeaa9303b78ce35d778882e3 151 Pfam PF01883 Iron-sulfur cluster assembly protein 6 73 9.6E-17 T 11-10-2018 IPR002744 MIP18 family-like TO73_1706 8f89f99e004fc67f56815facb6067ce6 282 SUPERFAMILY SSF56317 9 229 1.44E-21 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TO73_1706 8f89f99e004fc67f56815facb6067ce6 282 Gene3D G3DSA:3.60.110.10 36 271 2.2E-16 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TO73_1578 f41ed35e0a49d547b5f34616c26c69c2 206 Gene3D G3DSA:3.30.460.80 1 134 1.1E-49 T 11-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1578 f41ed35e0a49d547b5f34616c26c69c2 206 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 28 154 5.8E-39 T 11-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1578 f41ed35e0a49d547b5f34616c26c69c2 206 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 3 162 30.446 T 11-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1578 f41ed35e0a49d547b5f34616c26c69c2 206 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 115 136 - T 11-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1578 f41ed35e0a49d547b5f34616c26c69c2 206 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 86 137 7.0E-23 T 11-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1578 f41ed35e0a49d547b5f34616c26c69c2 206 SUPERFAMILY SSF143243 5 185 2.09E-52 T 11-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_2418 a4d97c985a7c95d7bf85b39c9bddaae6 292 Gene3D G3DSA:3.40.50.300 1 226 1.7E-61 T 11-10-2018 TO73_2418 a4d97c985a7c95d7bf85b39c9bddaae6 292 Pfam PF00005 ABC transporter 19 160 2.1E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_2418 a4d97c985a7c95d7bf85b39c9bddaae6 292 SMART SM00382 28 224 2.8E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2418 a4d97c985a7c95d7bf85b39c9bddaae6 292 SUPERFAMILY SSF52540 4 210 4.46E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2418 a4d97c985a7c95d7bf85b39c9bddaae6 292 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1639 544488d177b06f9294f73b84ebd27171 207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 178 0.005 T 11-10-2018 TO73_1639 544488d177b06f9294f73b84ebd27171 207 SUPERFAMILY SSF51735 2 200 1.65E-37 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1639 544488d177b06f9294f73b84ebd27171 207 Pfam PF00106 short chain dehydrogenase 3 173 1.3E-19 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1639 544488d177b06f9294f73b84ebd27171 207 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 121 149 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TO73_1639 544488d177b06f9294f73b84ebd27171 207 Gene3D G3DSA:3.40.50.720 1 204 4.6E-48 T 11-10-2018 TO73_1639 544488d177b06f9294f73b84ebd27171 207 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 76 3.9E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1639 544488d177b06f9294f73b84ebd27171 207 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.9E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1639 544488d177b06f9294f73b84ebd27171 207 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 153 3.9E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0786 d7e368872d624e14168a520882d159e2 494 SUPERFAMILY SSF51735 165 260 1.02E-8 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0786 d7e368872d624e14168a520882d159e2 494 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 39 494 1.2E-119 T 11-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase TO73_0786 d7e368872d624e14168a520882d159e2 494 Pfam PF13727 CoA-binding domain 89 261 6.4E-13 T 11-10-2018 TO73_0786 d7e368872d624e14168a520882d159e2 494 TIGRFAM TIGR03022 WbaP_sugtrans: undecaprenyl-phosphate galactose phosphotransferase WbaP 37 494 1.3E-152 T 11-10-2018 IPR017472 Undecaprenyl-phosphate galactose phosphotransferase, WbaP GO:0000271|GO:0005886|GO:0016021|GO:0016740 TO73_0786 d7e368872d624e14168a520882d159e2 494 Pfam PF02397 Bacterial sugar transferase 297 488 8.2E-66 T 11-10-2018 IPR003362 Bacterial sugar transferase TO73_0786 d7e368872d624e14168a520882d159e2 494 Gene3D G3DSA:3.40.50.720 164 280 9.4E-17 T 11-10-2018 TO73_1762 6a82d25a739c1053f472f0869036e6e0 141 Gene3D G3DSA:3.40.630.30 1 141 4.7E-71 T 11-10-2018 TO73_1762 6a82d25a739c1053f472f0869036e6e0 141 Pfam PF09390 Protein of unknown function (DUF1999) 24 139 1.4E-35 T 11-10-2018 IPR018987 Protein of unknown function DUF1999 TO73_1762 6a82d25a739c1053f472f0869036e6e0 141 SUPERFAMILY SSF55729 1 130 5.53E-52 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_1945 d0ba9485550b2d9658096ba7e2cd1588 139 SUPERFAMILY SSF52833 36 138 9.28E-33 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1945 d0ba9485550b2d9658096ba7e2cd1588 139 Gene3D G3DSA:3.40.30.10 28 138 4.0E-28 T 11-10-2018 TO73_1945 d0ba9485550b2d9658096ba7e2cd1588 139 PRINTS PR00421 Thioredoxin family signature 102 113 2.1E-6 T 11-10-2018 TO73_1945 d0ba9485550b2d9658096ba7e2cd1588 139 PRINTS PR00421 Thioredoxin family signature 54 62 2.1E-6 T 11-10-2018 TO73_1945 d0ba9485550b2d9658096ba7e2cd1588 139 PRINTS PR00421 Thioredoxin family signature 62 71 2.1E-6 T 11-10-2018 TO73_1945 d0ba9485550b2d9658096ba7e2cd1588 139 Pfam PF00085 Thioredoxin 43 134 2.4E-23 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 TO73_1945 d0ba9485550b2d9658096ba7e2cd1588 139 TIGRFAM TIGR01068 thioredoxin: thioredoxin 48 135 1.5E-32 T 11-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 SUPERFAMILY SSF56014 396 553 4.97E-36 T 11-10-2018 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 PRINTS PR00397 Sirohaem Fe-binding site signature 395 413 8.0E-7 T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 PRINTS PR00397 Sirohaem Fe-binding site signature 443 461 8.0E-7 T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 393 538 3.6E-13 T 11-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 Gene3D G3DSA:3.30.413.10 390 566 2.1E-40 T 11-10-2018 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 48 109 4.4E-17 T 11-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 318 384 5.0E-16 T 11-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 Gene3D G3DSA:3.30.413.10 118 299 7.5E-89 T 11-10-2018 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 SUPERFAMILY SSF55124 13 118 4.25E-25 T 11-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 SUPERFAMILY SSF56014 119 272 4.71E-42 T 11-10-2018 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 SUPERFAMILY SSF55124 250 406 7.03E-19 T 11-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 443 459 - T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 Gene3D G3DSA:3.90.480.10 51 374 7.5E-89 T 11-10-2018 TO73_0878 e4a1c7a33f71d5e538d1c47707f96e39 575 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 268 5.8E-37 T 11-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TO73_0122 bf63ee3240448baebdaa4e60840eba9c 375 SMART SM01002 148 310 1.1E-75 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TO73_0122 bf63ee3240448baebdaa4e60840eba9c 375 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 365 3.0E-65 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TO73_0122 bf63ee3240448baebdaa4e60840eba9c 375 Gene3D G3DSA:3.40.50.720 6 353 1.9E-140 T 11-10-2018 TO73_0122 bf63ee3240448baebdaa4e60840eba9c 375 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 11-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 TO73_0122 bf63ee3240448baebdaa4e60840eba9c 375 SMART SM01003 5 139 1.4E-60 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TO73_0122 bf63ee3240448baebdaa4e60840eba9c 375 SUPERFAMILY SSF52283 3 170 1.79E-48 T 11-10-2018 TO73_0122 bf63ee3240448baebdaa4e60840eba9c 375 Gene3D G3DSA:3.40.50.720 139 317 1.9E-140 T 11-10-2018 TO73_0122 bf63ee3240448baebdaa4e60840eba9c 375 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 6 139 4.3E-42 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TO73_0122 bf63ee3240448baebdaa4e60840eba9c 375 SUPERFAMILY SSF51735 139 317 7.45E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0680 6f2f14374d3c577056a29e3876a8f7c5 283 SMART SM01130 2 277 1.5E-53 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_0680 6f2f14374d3c577056a29e3876a8f7c5 283 PIRSF PIRSF001365 1 271 2.2E-56 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_0680 6f2f14374d3c577056a29e3876a8f7c5 283 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 124 154 - T 11-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TO73_0680 6f2f14374d3c577056a29e3876a8f7c5 283 Pfam PF00701 Dihydrodipicolinate synthetase family 2 259 5.4E-39 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_0680 6f2f14374d3c577056a29e3876a8f7c5 283 SUPERFAMILY SSF51569 2 263 5.23E-59 T 11-10-2018 TO73_0680 6f2f14374d3c577056a29e3876a8f7c5 283 PRINTS PR00146 Dihydrodipicolinate synthase signature 119 136 2.3E-8 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_0680 6f2f14374d3c577056a29e3876a8f7c5 283 PRINTS PR00146 Dihydrodipicolinate synthase signature 96 112 2.3E-8 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_0680 6f2f14374d3c577056a29e3876a8f7c5 283 PRINTS PR00146 Dihydrodipicolinate synthase signature 31 52 2.3E-8 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_0680 6f2f14374d3c577056a29e3876a8f7c5 283 Gene3D G3DSA:3.20.20.70 1 283 3.1E-101 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1588 792c2cd9699b2787bfe98c43381950dd 469 Pfam PF00361 Proton-conducting membrane transporter 112 399 1.4E-44 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1588 792c2cd9699b2787bfe98c43381950dd 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 307 326 1.4E-24 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1588 792c2cd9699b2787bfe98c43381950dd 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 219 243 1.4E-24 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1588 792c2cd9699b2787bfe98c43381950dd 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 118 137 1.4E-24 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1588 792c2cd9699b2787bfe98c43381950dd 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 359 385 1.4E-24 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1588 792c2cd9699b2787bfe98c43381950dd 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 148 172 1.4E-24 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1588 792c2cd9699b2787bfe98c43381950dd 469 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 33 456 2.6E-112 T 11-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_0835 28993ef0723131e987a07c98d8025022 160 Pfam PF00355 Rieske [2Fe-2S] domain 41 132 2.4E-10 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TO73_0835 28993ef0723131e987a07c98d8025022 160 Gene3D G3DSA:2.102.10.10 33 160 3.2E-39 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TO73_0835 28993ef0723131e987a07c98d8025022 160 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 25 1.4E-4 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TO73_0835 28993ef0723131e987a07c98d8025022 160 SUPERFAMILY SSF50022 3 146 9.69E-28 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TO73_0835 28993ef0723131e987a07c98d8025022 160 TIGRFAM TIGR02694 arsenite_ox_S: arsenite oxidase, small subunit 34 160 6.2E-68 T 11-10-2018 IPR014067 Arsenite oxidase, small subunit MetaCyc: PWY-7429 TO73_2846 616fd039d30f17d59cf17265968a8683 77 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 29 4.3E-5 T 11-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TO73_2846 616fd039d30f17d59cf17265968a8683 77 SUPERFAMILY SSF47598 2 45 2.22E-5 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TO73_0918 616fd039d30f17d59cf17265968a8683 77 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 29 4.3E-5 T 11-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TO73_0918 616fd039d30f17d59cf17265968a8683 77 SUPERFAMILY SSF47598 2 45 2.22E-5 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TO73_0023 613985a809c942927ef174a37c6a497e 152 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 152 30.138 T 11-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TO73_0023 613985a809c942927ef174a37c6a497e 152 SUPERFAMILY SSF69765 1 150 1.57E-46 T 11-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TO73_0023 613985a809c942927ef174a37c6a497e 152 Pfam PF02542 YgbB family 1 150 1.9E-46 T 11-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TO73_0023 613985a809c942927ef174a37c6a497e 152 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 150 5.3E-48 T 11-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TO73_0023 613985a809c942927ef174a37c6a497e 152 Gene3D G3DSA:3.30.1330.50 1 152 2.7E-52 T 11-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TO73_0023 613985a809c942927ef174a37c6a497e 152 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 11-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TO73_0402 926ce64b1e45291f17d1137034adef29 116 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 2 111 1.0E-52 T 11-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0402 926ce64b1e45291f17d1137034adef29 116 PIRSF PIRSF002131 1 114 8.3E-49 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TO73_0402 926ce64b1e45291f17d1137034adef29 116 Pfam PF00411 Ribosomal protein S11 4 113 2.4E-42 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TO73_0402 926ce64b1e45291f17d1137034adef29 116 ProSitePatterns PS00054 Ribosomal protein S11 signature. 82 104 - T 11-10-2018 IPR018102 Ribosomal S11, conserved site TO73_0402 926ce64b1e45291f17d1137034adef29 116 SUPERFAMILY SSF53137 3 114 7.85E-45 T 11-10-2018 TO73_0402 926ce64b1e45291f17d1137034adef29 116 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 114 28.81 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TO73_0402 926ce64b1e45291f17d1137034adef29 116 Gene3D G3DSA:3.30.420.80 1 116 4.1E-54 T 11-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TO73_2259 115a90ae8ead5f15bba44bfb90ac3e22 371 SUPERFAMILY SSF53187 3 371 3.52E-45 T 11-10-2018 TO73_2259 115a90ae8ead5f15bba44bfb90ac3e22 371 PIRSF PIRSF037238 1 371 2.7E-132 T 11-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase TO73_2259 115a90ae8ead5f15bba44bfb90ac3e22 371 Pfam PF01546 Peptidase family M20/M25/M40 76 369 1.7E-24 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 TO73_2259 115a90ae8ead5f15bba44bfb90ac3e22 371 Pfam PF07687 Peptidase dimerisation domain 175 268 5.8E-16 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain TO73_2259 115a90ae8ead5f15bba44bfb90ac3e22 371 Gene3D G3DSA:3.30.70.360 178 285 6.2E-108 T 11-10-2018 TO73_2259 115a90ae8ead5f15bba44bfb90ac3e22 371 Gene3D G3DSA:3.40.630.10 17 360 6.2E-108 T 11-10-2018 TO73_2259 115a90ae8ead5f15bba44bfb90ac3e22 371 SUPERFAMILY SSF55031 178 281 1.02E-16 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TO73_1285 8d517a69aad9685dee16742eb003955f 862 PRINTS PR00986 Valyl-tRNA synthetase signature 346 359 1.8E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TO73_1285 8d517a69aad9685dee16742eb003955f 862 PRINTS PR00986 Valyl-tRNA synthetase signature 480 498 1.8E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TO73_1285 8d517a69aad9685dee16742eb003955f 862 PRINTS PR00986 Valyl-tRNA synthetase signature 449 470 1.8E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TO73_1285 8d517a69aad9685dee16742eb003955f 862 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 1.8E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TO73_1285 8d517a69aad9685dee16742eb003955f 862 PRINTS PR00986 Valyl-tRNA synthetase signature 229 246 1.8E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TO73_1285 8d517a69aad9685dee16742eb003955f 862 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1285 8d517a69aad9685dee16742eb003955f 862 Pfam PF08264 Anticodon-binding domain of tRNA 607 748 4.7E-36 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TO73_1285 8d517a69aad9685dee16742eb003955f 862 Gene3D G3DSA:1.10.730.10 3 734 0.0 T 11-10-2018 TO73_1285 8d517a69aad9685dee16742eb003955f 862 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 797 861 2.3E-19 T 11-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 TO73_1285 8d517a69aad9685dee16742eb003955f 862 Gene3D G3DSA:3.40.50.620 23 529 0.0 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1285 8d517a69aad9685dee16742eb003955f 862 TIGRFAM TIGR00422 valS: valine--tRNA ligase 4 844 1.3E-299 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TO73_1285 8d517a69aad9685dee16742eb003955f 862 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 16 568 2.1E-186 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1285 8d517a69aad9685dee16742eb003955f 862 Gene3D G3DSA:3.30.1170.10 740 789 3.7E-24 T 11-10-2018 TO73_1285 8d517a69aad9685dee16742eb003955f 862 Gene3D G3DSA:1.10.287.380 790 862 4.9E-27 T 11-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 TO73_1285 8d517a69aad9685dee16742eb003955f 862 SUPERFAMILY SSF46589 797 861 2.98E-10 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TO73_1285 8d517a69aad9685dee16742eb003955f 862 SUPERFAMILY SSF50677 192 339 1.7E-53 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TO73_1285 8d517a69aad9685dee16742eb003955f 862 Hamap MF_02004 Valine--tRNA ligase [valS]. 3 862 14.582 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TO73_1285 8d517a69aad9685dee16742eb003955f 862 SUPERFAMILY SSF52374 2 578 7.78E-142 T 11-10-2018 TO73_1285 8d517a69aad9685dee16742eb003955f 862 SUPERFAMILY SSF47323 579 794 6.92E-52 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1285 8d517a69aad9685dee16742eb003955f 862 Gene3D G3DSA:3.90.740.10 175 343 0.0 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TO73_0143 c02c3313a6d04876acf61a0adb12f080 294 SUPERFAMILY SSF55681 64 244 4.8E-42 T 11-10-2018 TO73_0143 c02c3313a6d04876acf61a0adb12f080 294 Gene3D G3DSA:3.30.930.10 58 248 4.2E-46 T 11-10-2018 TO73_0143 c02c3313a6d04876acf61a0adb12f080 294 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 73 278 4.0E-44 T 11-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TO73_0143 c02c3313a6d04876acf61a0adb12f080 294 Pfam PF03099 Biotin/lipoate A/B protein ligase family 77 195 2.3E-9 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TO73_0143 c02c3313a6d04876acf61a0adb12f080 294 Gene3D G3DSA:1.10.10.10 2 53 1.1E-9 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0143 c02c3313a6d04876acf61a0adb12f080 294 SUPERFAMILY SSF46785 8 52 5.55E-6 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0143 c02c3313a6d04876acf61a0adb12f080 294 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 1 290 27.997 T 11-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 TO73_0143 c02c3313a6d04876acf61a0adb12f080 294 Pfam PF08279 HTH domain 13 50 2.2E-7 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 4.4E-29 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 307 320 4.4E-29 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 204 215 4.4E-29 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 235 248 4.4E-29 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 283 299 4.4E-29 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 866 2.8E-269 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 SUPERFAMILY SSF55681 2 254 1.52E-89 T 11-10-2018 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 Gene3D G3DSA:3.30.54.20 634 693 1.0E-51 T 11-10-2018 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 SUPERFAMILY SSF55186 565 723 5.1E-49 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 SMART SM00863 663 712 1.1E-18 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 Gene3D G3DSA:2.40.30.130 459 563 1.2E-10 T 11-10-2018 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 Pfam PF02272 DHHA1 domain 748 876 7.7E-13 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 Gene3D G3DSA:3.30.980.10 566 711 1.0E-51 T 11-10-2018 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 SUPERFAMILY SSF101353 256 470 3.79E-63 T 11-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 Gene3D G3DSA:3.30.930.10 1 251 1.5E-97 T 11-10-2018 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 Pfam PF01411 tRNA synthetases class II (A) 5 566 8.7E-217 T 11-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 881 168.719 T 11-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 SUPERFAMILY SSF50447 464 563 4.59E-18 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 Gene3D G3DSA:3.10.310.40 781 879 3.2E-10 T 11-10-2018 TO73_0301 ea2b9d0e935de8328ec93b22bb54bc06 881 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 663 712 1.1E-16 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TO73_2131 2f9f63daea52540db85d00ca72e8c648 185 Pfam PF09189 Domain of unknown function (DUF1952) 110 182 6.9E-30 T 11-10-2018 IPR015272 Molybdopterin cofactor biosynthesis MoaD-related, C-terminal TO73_2131 2f9f63daea52540db85d00ca72e8c648 185 SUPERFAMILY SSF103239 109 182 1.7E-29 T 11-10-2018 IPR036473 Molybdopterin cofactor biosynthesis MoaD-related, C-terminal domain superfamily TO73_2131 2f9f63daea52540db85d00ca72e8c648 185 Gene3D G3DSA:3.30.1370.80 103 185 8.3E-38 T 11-10-2018 IPR036473 Molybdopterin cofactor biosynthesis MoaD-related, C-terminal domain superfamily TO73_2131 2f9f63daea52540db85d00ca72e8c648 185 Pfam PF02597 ThiS family 19 103 1.0E-13 T 11-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TO73_2131 2f9f63daea52540db85d00ca72e8c648 185 Gene3D G3DSA:3.10.20.30 17 101 1.4E-27 T 11-10-2018 IPR012675 Beta-grasp domain superfamily TO73_2131 2f9f63daea52540db85d00ca72e8c648 185 SUPERFAMILY SSF54285 18 103 1.25E-19 T 11-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TO73_2131 2f9f63daea52540db85d00ca72e8c648 185 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 18 103 1.7E-17 T 11-10-2018 IPR010038 MoaD, archaeal-type TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.5E-8 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.5E-8 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.5E-8 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.3E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 5.3E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 5.3E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.3E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.3E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 5.3E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 180 9.9E-6 T 11-10-2018 TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 239 1.5E-68 T 11-10-2018 TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 Gene3D G3DSA:3.40.50.720 2 246 1.0E-88 T 11-10-2018 TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TO73_0971 53b43745ec2be0862133b85b48dca3c9 246 SUPERFAMILY SSF51735 5 241 1.44E-82 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0553 6cc96eaaebf4b779236e490fb20da17e 395 PIRSF PIRSF001456 9 392 4.2E-117 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TO73_0553 6cc96eaaebf4b779236e490fb20da17e 395 Gene3D G3DSA:3.60.150.10 13 395 1.4E-142 T 11-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TO73_0553 6cc96eaaebf4b779236e490fb20da17e 395 Pfam PF01264 Chorismate synthase 13 370 2.9E-111 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TO73_0553 6cc96eaaebf4b779236e490fb20da17e 395 ProSitePatterns PS00787 Chorismate synthase signature 1. 19 34 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TO73_0553 6cc96eaaebf4b779236e490fb20da17e 395 Hamap MF_00300 Chorismate synthase [aroC]. 13 377 34.563 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TO73_0553 6cc96eaaebf4b779236e490fb20da17e 395 SUPERFAMILY SSF103263 12 394 1.44E-136 T 11-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TO73_0553 6cc96eaaebf4b779236e490fb20da17e 395 ProSitePatterns PS00788 Chorismate synthase signature 2. 139 155 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TO73_0553 6cc96eaaebf4b779236e490fb20da17e 395 TIGRFAM TIGR00033 aroC: chorismate synthase 13 375 3.5E-115 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 Pfam PF00403 Heavy-metal-associated domain 1 54 7.5E-6 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 124 667 3.2E-148 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 376 382 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 Gene3D G3DSA:3.40.1110.10 385 498 2.5E-64 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 SUPERFAMILY SSF81665 127 625 3.4E-14 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 125 668 1.7E-127 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 Gene3D G3DSA:2.70.150.20 174 278 1.3E-26 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 Pfam PF00122 E1-E2 ATPase 175 353 8.9E-44 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 SUPERFAMILY SSF56784 373 665 1.75E-37 T 11-10-2018 IPR036412 HAD-like superfamily TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 Gene3D G3DSA:3.30.70.100 1 59 1.6E-10 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 Pfam PF00702 haloacid dehalogenase-like hydrolase 371 580 5.6E-30 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 Gene3D G3DSA:3.40.50.1000 355 615 2.5E-64 T 11-10-2018 IPR023214 HAD superfamily TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 SUPERFAMILY SSF81653 177 271 9.29E-21 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 147 395 2.2E-33 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 467 642 7.5E-29 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 523 2.0E-19 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 224 238 2.0E-19 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 602 2.0E-19 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 374 388 2.0E-19 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 567 586 2.0E-19 T 11-10-2018 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 SUPERFAMILY SSF81660 392 500 8.5E-13 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TO73_1648 a07e1e5cadc400993a5ee3f963a31bfd 672 SUPERFAMILY SSF55008 1 57 7.85E-10 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TO73_0439 0ec469b50954a8e6daa55bd25c9c805f 463 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 7 447 44.936 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TO73_0439 0ec469b50954a8e6daa55bd25c9c805f 463 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 8 448 1.2E-152 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TO73_0439 0ec469b50954a8e6daa55bd25c9c805f 463 Gene3D G3DSA:3.40.50.2020 270 433 2.0E-149 T 11-10-2018 TO73_0439 0ec469b50954a8e6daa55bd25c9c805f 463 SUPERFAMILY SSF56235 8 252 3.26E-61 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_0439 0ec469b50954a8e6daa55bd25c9c805f 463 PIRSF PIRSF000485 4 461 5.6E-164 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TO73_0439 0ec469b50954a8e6daa55bd25c9c805f 463 Pfam PF13537 Glutamine amidotransferase domain 84 209 4.2E-22 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TO73_0439 0ec469b50954a8e6daa55bd25c9c805f 463 Pfam PF00156 Phosphoribosyl transferase domain 259 382 1.3E-11 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TO73_0439 0ec469b50954a8e6daa55bd25c9c805f 463 Gene3D G3DSA:3.60.20.10 8 448 2.0E-149 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_0439 0ec469b50954a8e6daa55bd25c9c805f 463 SUPERFAMILY SSF53271 245 454 6.69E-69 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 312 334 - T 11-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 SMART SM00493 25 124 6.3E-29 T 11-10-2018 IPR006171 TOPRIM domain TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Gene3D G3DSA:2.70.20.10 206 493 7.0E-159 T 11-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Pfam PF01131 DNA topoisomerase 149 583 3.8E-127 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Pfam PF01751 Toprim domain 26 134 1.1E-23 T 11-10-2018 IPR006171 TOPRIM domain TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Gene3D G3DSA:1.10.460.10 156 586 7.0E-159 T 11-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 27 634 1.2E-214 T 11-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Gene3D G3DSA:3.40.50.140 21 155 1.7E-48 T 11-10-2018 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Gene3D G3DSA:3.30.65.10 638 681 3.4E-8 T 11-10-2018 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Gene3D G3DSA:3.30.65.10 587 637 1.2E-6 T 11-10-2018 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 SMART SM00436 125 214 5.6E-46 T 11-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 SUPERFAMILY SSF56712 25 610 5.36E-183 T 11-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 SMART SM00437 275 546 3.1E-111 T 11-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 725 746 1.6 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 684 717 6.9E-4 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 600 636 3.2E-13 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 644 677 5.2E-14 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 SUPERFAMILY SSF57783 643 677 6.63E-11 T 11-10-2018 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Hamap MF_00952 DNA topoisomerase 1 [topA]. 25 708 52.205 T 11-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 98 111 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 509 523 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 184 202 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 403 419 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 325 334 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TO73_2062 5b5c5051ddb483b563470b46c8a25917 833 Gene3D G3DSA:1.10.290.10 283 418 7.0E-159 T 11-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TO73_0090 37ffa25dcac47c9ff1eccae5d8b5d112 263 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 262 3.7E-75 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TO73_0090 37ffa25dcac47c9ff1eccae5d8b5d112 263 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 263 39.652 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TO73_0090 37ffa25dcac47c9ff1eccae5d8b5d112 263 SUPERFAMILY SSF64005 25 257 3.14E-81 T 11-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TO73_0090 37ffa25dcac47c9ff1eccae5d8b5d112 263 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 208 225 - T 11-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TO73_0090 37ffa25dcac47c9ff1eccae5d8b5d112 263 Pfam PF01255 Putative undecaprenyl diphosphate synthase 36 262 9.6E-79 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TO73_0090 37ffa25dcac47c9ff1eccae5d8b5d112 263 Gene3D G3DSA:3.40.1180.10 15 263 7.0E-97 T 11-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TO73_0392 54594dd3d2f5f8b800082c94d083e02f 112 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 112 6.6E-39 T 11-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0392 54594dd3d2f5f8b800082c94d083e02f 112 SUPERFAMILY SSF53137 6 110 6.32E-47 T 11-10-2018 TO73_0392 54594dd3d2f5f8b800082c94d083e02f 112 Gene3D G3DSA:3.30.420.100 1 112 5.2E-41 T 11-10-2018 TO73_0392 54594dd3d2f5f8b800082c94d083e02f 112 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 112 26.938 T 11-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0392 54594dd3d2f5f8b800082c94d083e02f 112 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 3 112 2.6E-39 T 11-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1749 f13932109a9e1fbea702af5e3c739513 249 SUPERFAMILY SSF52172 6 129 5.98E-36 T 11-10-2018 IPR011006 CheY-like superfamily TO73_1749 f13932109a9e1fbea702af5e3c739513 249 SMART SM00448 5 117 4.4E-33 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1749 f13932109a9e1fbea702af5e3c739513 249 Pfam PF00072 Response regulator receiver domain 8 118 7.6E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1749 f13932109a9e1fbea702af5e3c739513 249 Gene3D G3DSA:3.40.50.12740 4 192 2.4E-38 T 11-10-2018 TO73_1749 f13932109a9e1fbea702af5e3c739513 249 Pfam PF08463 EcoEI R protein C-terminal 137 214 2.0E-5 T 11-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 TO73_0451 479262e8f298ed3dcbc722e5e5d38e21 182 SMART SM00867 14 180 5.4E-17 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TO73_0451 479262e8f298ed3dcbc722e5e5d38e21 182 SUPERFAMILY SSF101874 30 181 2.49E-23 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TO73_0451 479262e8f298ed3dcbc722e5e5d38e21 182 Gene3D G3DSA:2.40.128.110 21 182 3.4E-25 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TO73_0451 479262e8f298ed3dcbc722e5e5d38e21 182 Pfam PF04264 YceI-like domain 33 178 1.3E-19 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 Gene3D G3DSA:3.40.50.10490 66 203 6.7E-128 T 11-10-2018 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 389 406 - T 11-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 Gene3D G3DSA:3.40.50.10490 204 409 6.7E-128 T 11-10-2018 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 SUPERFAMILY SSF53697 37 415 4.11E-96 T 11-10-2018 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 5 416 23.014 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 PRINTS PR00662 Glucose-6-phosphate isomerase signature 69 88 4.8E-22 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 PRINTS PR00662 Glucose-6-phosphate isomerase signature 178 196 4.8E-22 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 PRINTS PR00662 Glucose-6-phosphate isomerase signature 250 271 4.8E-22 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 PRINTS PR00662 Glucose-6-phosphate isomerase signature 357 375 4.8E-22 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 PRINTS PR00662 Glucose-6-phosphate isomerase signature 389 402 4.8E-22 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_2240 8f93069532d782a92e439c34b47f8d0c 417 Pfam PF00342 Phosphoglucose isomerase 66 412 3.5E-36 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_2829 d463d2248a00fd0b38341cdd90aa2361 303 Pfam PF01497 Periplasmic binding protein 40 271 1.3E-26 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain TO73_2829 d463d2248a00fd0b38341cdd90aa2361 303 Gene3D G3DSA:3.40.50.1980 34 157 4.6E-41 T 11-10-2018 TO73_2829 d463d2248a00fd0b38341cdd90aa2361 303 Gene3D G3DSA:3.40.50.1980 160 293 2.0E-38 T 11-10-2018 TO73_2829 d463d2248a00fd0b38341cdd90aa2361 303 SUPERFAMILY SSF53807 17 292 1.18E-50 T 11-10-2018 TO73_2814 c292dc29c0cd2f682e1280258b689c49 87 Gene3D G3DSA:3.40.1620.10 1 51 2.0E-21 T 11-10-2018 TO73_2814 c292dc29c0cd2f682e1280258b689c49 87 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 67 4.4E-17 T 11-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TO73_2814 c292dc29c0cd2f682e1280258b689c49 87 SUPERFAMILY SSF143120 3 49 1.83E-12 T 11-10-2018 IPR036165 YefM-like superfamily TO73_2814 c292dc29c0cd2f682e1280258b689c49 87 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 52 2.4E-13 T 11-10-2018 TO73_0558 64cf3515d74128d337864e31eab7f09f 377 Gene3D G3DSA:3.30.420.40 16 371 3.9E-107 T 11-10-2018 TO73_0558 64cf3515d74128d337864e31eab7f09f 377 SUPERFAMILY SSF53067 57 175 2.4E-16 T 11-10-2018 TO73_0558 64cf3515d74128d337864e31eab7f09f 377 Pfam PF11104 Type IV pilus assembly protein PilM; 17 250 1.0E-40 T 11-10-2018 IPR005883 Type IV pilus assembly protein PilM TO73_0558 64cf3515d74128d337864e31eab7f09f 377 Pfam PF11104 Type IV pilus assembly protein PilM; 280 372 7.7E-11 T 11-10-2018 IPR005883 Type IV pilus assembly protein PilM TO73_0558 64cf3515d74128d337864e31eab7f09f 377 Gene3D G3DSA:3.30.1490.300 89 149 3.9E-107 T 11-10-2018 TO73_0558 64cf3515d74128d337864e31eab7f09f 377 Gene3D G3DSA:3.30.420.40 188 336 3.9E-107 T 11-10-2018 TO73_0558 64cf3515d74128d337864e31eab7f09f 377 PIRSF PIRSF019169 1 374 2.4E-98 T 11-10-2018 IPR005883 Type IV pilus assembly protein PilM TO73_0558 64cf3515d74128d337864e31eab7f09f 377 SUPERFAMILY SSF53067 190 372 4.21E-20 T 11-10-2018 TO73_0558 64cf3515d74128d337864e31eab7f09f 377 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 15 373 5.7E-89 T 11-10-2018 IPR005883 Type IV pilus assembly protein PilM TO73_1758 32e3d576f88f8019b87fbe9f26a206d1 244 SUPERFAMILY SSF75625 3 237 6.67E-80 T 11-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1758 32e3d576f88f8019b87fbe9f26a206d1 244 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 237 32.257 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1758 32e3d576f88f8019b87fbe9f26a206d1 244 Gene3D G3DSA:1.10.10.200 1 82 6.1E-27 T 11-10-2018 IPR017856 Integrase-like, N-terminal TO73_1758 32e3d576f88f8019b87fbe9f26a206d1 244 Gene3D G3DSA:3.30.70.980 136 201 8.6E-51 T 11-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1758 32e3d576f88f8019b87fbe9f26a206d1 244 Pfam PF01709 Transcriptional regulator 5 235 1.2E-81 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1758 32e3d576f88f8019b87fbe9f26a206d1 244 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 6.7E-81 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1758 32e3d576f88f8019b87fbe9f26a206d1 244 Gene3D G3DSA:3.30.70.980 87 234 8.6E-51 T 11-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1077 be622d7d4e3e4131b5c7a7f1d0f7e084 260 SUPERFAMILY SSF55729 6 117 4.12E-12 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_1077 be622d7d4e3e4131b5c7a7f1d0f7e084 260 Gene3D G3DSA:3.40.630.30 6 142 1.1E-11 T 11-10-2018 TO73_1077 be622d7d4e3e4131b5c7a7f1d0f7e084 260 Pfam PF00583 Acetyltransferase (GNAT) family 19 115 4.8E-6 T 11-10-2018 IPR000182 GNAT domain TO73_1074 4f893fd549a859133b0a06d351fdfce7 89 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 84 2.0E-12 T 11-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TO73_1074 4f893fd549a859133b0a06d351fdfce7 89 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 5 89 3.5E-15 T 11-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TO73_1074 4f893fd549a859133b0a06d351fdfce7 89 Gene3D G3DSA:1.10.8.990 66 83 8.3E-6 T 11-10-2018 TO73_1074 4f893fd549a859133b0a06d351fdfce7 89 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 89 18.221 T 11-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TO73_1074 4f893fd549a859133b0a06d351fdfce7 89 Gene3D G3DSA:1.10.20.60 1 45 6.5E-17 T 11-10-2018 TO73_1074 4f893fd549a859133b0a06d351fdfce7 89 SUPERFAMILY SSF141000 3 87 2.22E-17 T 11-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 Gene3D G3DSA:3.40.50.720 1 226 1.1E-65 T 11-10-2018 TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 SUPERFAMILY SSF51735 2 210 6.24E-59 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 Pfam PF00106 short chain dehydrogenase 2 183 2.0E-50 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.1E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.1E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 1.1E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.9E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 208 1.9E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.9E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.9E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.9E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0722 0cfeb37faf8e85304b55c91ba89a0ca7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.9E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 SUPERFAMILY SSF55874 302 462 3.41E-46 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 Gene3D G3DSA:1.10.287.130 198 311 3.5E-25 T 11-10-2018 TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 SUPERFAMILY SSF47384 229 309 5.89E-21 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 Gene3D G3DSA:3.30.565.10 320 462 6.2E-45 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 SMART SM00304 194 245 0.0025 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 460 2.0E-31 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 SMART SM00388 246 312 2.1E-21 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 3.2E-21 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 3.2E-21 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 3.2E-21 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 415 3.2E-21 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 247 310 1.3E-18 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_0462 51933c29b6117a6cc10930e9e4ac115b 468 SMART SM00387 352 462 6.8E-45 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_1658 130ea44bfc28b3495e1faffedd6238ae 276 SMART SM00518 3 267 5.0E-57 T 11-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TO73_1658 130ea44bfc28b3495e1faffedd6238ae 276 Pfam PF01261 Xylose isomerase-like TIM barrel 20 227 1.2E-21 T 11-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TO73_1658 130ea44bfc28b3495e1faffedd6238ae 276 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 267 31.844 T 11-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TO73_1658 130ea44bfc28b3495e1faffedd6238ae 276 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 203 219 - T 11-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 TO73_1658 130ea44bfc28b3495e1faffedd6238ae 276 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 4 267 3.2E-58 T 11-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TO73_1658 130ea44bfc28b3495e1faffedd6238ae 276 SUPERFAMILY SSF51658 3 267 4.06E-65 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily TO73_1658 130ea44bfc28b3495e1faffedd6238ae 276 Gene3D G3DSA:3.20.20.150 1 270 1.1E-88 T 11-10-2018 TO73_2018 6c7a35675a2407a5069929d789689676 369 SMART SM01003 4 135 1.7E-75 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TO73_2018 6c7a35675a2407a5069929d789689676 369 PIRSF PIRSF000183 1 368 2.2E-185 T 11-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 TO73_2018 6c7a35675a2407a5069929d789689676 369 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 367 1.9E-171 T 11-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 TO73_2018 6c7a35675a2407a5069929d789689676 369 SUPERFAMILY SSF52283 1 357 1.7E-67 T 11-10-2018 TO73_2018 6c7a35675a2407a5069929d789689676 369 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 135 7.0E-44 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TO73_2018 6c7a35675a2407a5069929d789689676 369 SMART SM01002 147 295 1.3E-87 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TO73_2018 6c7a35675a2407a5069929d789689676 369 Gene3D G3DSA:3.40.50.720 3 349 4.8E-140 T 11-10-2018 TO73_2018 6c7a35675a2407a5069929d789689676 369 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 171 196 - T 11-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 TO73_2018 6c7a35675a2407a5069929d789689676 369 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 139 349 7.3E-87 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TO73_2018 6c7a35675a2407a5069929d789689676 369 SUPERFAMILY SSF51735 135 301 9.18E-50 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_2018 6c7a35675a2407a5069929d789689676 369 Gene3D G3DSA:3.40.50.720 128 303 4.8E-140 T 11-10-2018 TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 PIRSF PIRSF004749 1 187 1.8E-51 T 11-10-2018 IPR023635 Peptide deformylase TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 7 169 4.9E-40 T 11-10-2018 IPR023635 Peptide deformylase TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 Gene3D G3DSA:3.90.45.10 1 190 1.0E-76 T 11-10-2018 IPR036821 Peptide deformylase superfamily TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 SUPERFAMILY SSF56420 1 171 1.22E-57 T 11-10-2018 IPR036821 Peptide deformylase superfamily TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 Hamap MF_00163 Peptide deformylase [def]. 1 173 30.588 T 11-10-2018 IPR023635 Peptide deformylase TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 PRINTS PR01576 Peptide deformylase signature 131 160 3.7E-37 T 11-10-2018 IPR023635 Peptide deformylase TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 PRINTS PR01576 Peptide deformylase signature 99 110 3.7E-37 T 11-10-2018 IPR023635 Peptide deformylase TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 PRINTS PR01576 Peptide deformylase signature 112 130 3.7E-37 T 11-10-2018 IPR023635 Peptide deformylase TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 PRINTS PR01576 Peptide deformylase signature 31 60 3.7E-37 T 11-10-2018 IPR023635 Peptide deformylase TO73_2317 e76be25c98a6c70561a5bb6c3c6dbf50 190 Pfam PF01327 Polypeptide deformylase 3 163 9.8E-51 T 11-10-2018 IPR023635 Peptide deformylase TO73_0055 3e71e92df6af5f90dde0eeef4bdd8ae9 333 Gene3D G3DSA:3.30.1330.10 1 166 1.9E-54 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TO73_0055 3e71e92df6af5f90dde0eeef4bdd8ae9 333 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 320 2.0E-102 T 11-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_0055 3e71e92df6af5f90dde0eeef4bdd8ae9 333 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 1 333 38.276 T 11-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_0055 3e71e92df6af5f90dde0eeef4bdd8ae9 333 Pfam PF00586 AIR synthase related protein, N-terminal domain 56 160 3.0E-16 T 11-10-2018 IPR016188 PurM-like, N-terminal domain TO73_0055 3e71e92df6af5f90dde0eeef4bdd8ae9 333 Pfam PF02769 AIR synthase related protein, C-terminal domain 172 330 4.5E-24 T 11-10-2018 IPR010918 PurM-like, C-terminal domain TO73_0055 3e71e92df6af5f90dde0eeef4bdd8ae9 333 Gene3D G3DSA:3.90.650.10 167 333 1.1E-62 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TO73_0055 3e71e92df6af5f90dde0eeef4bdd8ae9 333 SUPERFAMILY SSF56042 168 331 1.74E-49 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TO73_0055 3e71e92df6af5f90dde0eeef4bdd8ae9 333 SUPERFAMILY SSF55326 2 165 3.29E-41 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 SUPERFAMILY SSF53901 273 394 2.56E-45 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 Gene3D G3DSA:3.40.47.10 129 391 2.2E-155 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 11-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 Pfam PF02803 Thiolase, C-terminal domain 272 393 3.1E-49 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 393 3.1E-146 T 11-10-2018 IPR002155 Thiolase GO:0016747 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 SUPERFAMILY SSF53901 3 272 1.8E-78 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 PIRSF PIRSF000429 1 396 2.8E-140 T 11-10-2018 IPR002155 Thiolase GO:0016747 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 Gene3D G3DSA:3.40.47.10 6 278 2.2E-155 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 TO73_1061 fd86d23ffc2ae279beab7f4364c2261c 397 Pfam PF00108 Thiolase, N-terminal domain 5 265 8.0E-75 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TO73_2850 09689320f95d106efa075c77eeca7894 349 SUPERFAMILY SSF81901 44 132 9.29E-16 T 11-10-2018 TO73_2850 09689320f95d106efa075c77eeca7894 349 Gene3D G3DSA:1.25.40.10 28 348 1.7E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2850 09689320f95d106efa075c77eeca7894 349 SMART SM00671 61 96 0.55 T 11-10-2018 IPR006597 Sel1-like repeat TO73_2850 09689320f95d106efa075c77eeca7894 349 SMART SM00671 97 132 0.009 T 11-10-2018 IPR006597 Sel1-like repeat TO73_2850 09689320f95d106efa075c77eeca7894 349 Pfam PF08238 Sel1 repeat 219 239 13.0 T 11-10-2018 IPR006597 Sel1-like repeat TO73_2850 09689320f95d106efa075c77eeca7894 349 Pfam PF08238 Sel1 repeat 61 88 0.008 T 11-10-2018 IPR006597 Sel1-like repeat TO73_2850 09689320f95d106efa075c77eeca7894 349 Pfam PF08238 Sel1 repeat 101 132 0.0094 T 11-10-2018 IPR006597 Sel1-like repeat TO73_2850 09689320f95d106efa075c77eeca7894 349 Pfam PF08238 Sel1 repeat 198 211 61.0 T 11-10-2018 IPR006597 Sel1-like repeat TO73_2337 8c7530c8c29ed370e99bcfde991ed108 146 TIGRFAM TIGR00077 lspA: signal peptidase II 5 139 9.4E-29 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TO73_2337 8c7530c8c29ed370e99bcfde991ed108 146 ProSitePatterns PS00855 Signal peptidases II signature. 86 98 - T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TO73_2337 8c7530c8c29ed370e99bcfde991ed108 146 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 122 138 1.9E-16 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TO73_2337 8c7530c8c29ed370e99bcfde991ed108 146 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 83 98 1.9E-16 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TO73_2337 8c7530c8c29ed370e99bcfde991ed108 146 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 40 48 1.9E-16 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TO73_2337 8c7530c8c29ed370e99bcfde991ed108 146 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 146 13.014 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TO73_2337 8c7530c8c29ed370e99bcfde991ed108 146 Pfam PF01252 Signal peptidase (SPase) II 4 138 1.8E-29 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TO73_2105 3d7fdc109d3d1f826f3459a528d219a9 569 SMART SM00642 110 497 5.1E-73 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TO73_2105 3d7fdc109d3d1f826f3459a528d219a9 569 SUPERFAMILY SSF51445 100 506 7.31E-91 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily TO73_2105 3d7fdc109d3d1f826f3459a528d219a9 569 Gene3D G3DSA:3.20.20.80 99 499 4.6E-113 T 11-10-2018 TO73_2105 3d7fdc109d3d1f826f3459a528d219a9 569 Pfam PF00128 Alpha amylase, catalytic domain 261 459 5.8E-23 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TO73_2105 3d7fdc109d3d1f826f3459a528d219a9 569 Pfam PF00128 Alpha amylase, catalytic domain 157 254 5.2E-31 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TO73_0264 7470e61b39fd5812ef63b415442bbe2d 336 Pfam PF00483 Nucleotidyl transferase 5 270 5.4E-42 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TO73_0264 7470e61b39fd5812ef63b415442bbe2d 336 SUPERFAMILY SSF159283 268 334 1.11E-13 T 11-10-2018 TO73_0264 7470e61b39fd5812ef63b415442bbe2d 336 Gene3D G3DSA:3.90.550.10 1 335 8.6E-111 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0264 7470e61b39fd5812ef63b415442bbe2d 336 SUPERFAMILY SSF53448 3 264 8.45E-69 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1764 869218e3c1fb597dbfba13da3ad46b3a 733 Pfam PF00271 Helicase conserved C-terminal domain 282 378 1.9E-15 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_1764 869218e3c1fb597dbfba13da3ad46b3a 733 SMART SM00487 53 264 4.5E-24 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_1764 869218e3c1fb597dbfba13da3ad46b3a 733 Gene3D G3DSA:3.40.50.300 261 408 1.1E-25 T 11-10-2018 TO73_1764 869218e3c1fb597dbfba13da3ad46b3a 733 Gene3D G3DSA:3.40.50.300 52 239 4.4E-36 T 11-10-2018 TO73_1764 869218e3c1fb597dbfba13da3ad46b3a 733 Pfam PF00270 DEAD/DEAH box helicase 59 226 3.1E-21 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TO73_1764 869218e3c1fb597dbfba13da3ad46b3a 733 SUPERFAMILY SSF52540 101 398 1.35E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1764 869218e3c1fb597dbfba13da3ad46b3a 733 Pfam PF09369 Domain of unknown function (DUF1998) 616 699 7.0E-22 T 11-10-2018 IPR018973 DEAD/DEAH-box helicase, putative TO73_1764 869218e3c1fb597dbfba13da3ad46b3a 733 SMART SM00490 295 379 1.5E-16 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_0473 ffedb7877bea99fc07f505113100bd4a 438 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 6 421 3.1E-99 T 11-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TO73_0473 ffedb7877bea99fc07f505113100bd4a 438 Gene3D G3DSA:3.80.30.20 139 367 5.1E-68 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TO73_0473 ffedb7877bea99fc07f505113100bd4a 438 SUPERFAMILY SSF102114 120 359 1.7E-49 T 11-10-2018 TO73_0473 ffedb7877bea99fc07f505113100bd4a 438 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 146 166 - T 11-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TO73_0473 ffedb7877bea99fc07f505113100bd4a 438 Pfam PF04055 Radical SAM superfamily 148 314 2.3E-21 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_0473 ffedb7877bea99fc07f505113100bd4a 438 Gene3D G3DSA:3.40.50.12160 4 124 1.4E-18 T 11-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TO73_0473 ffedb7877bea99fc07f505113100bd4a 438 SMART SM00729 142 359 1.1E-42 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_0473 ffedb7877bea99fc07f505113100bd4a 438 Pfam PF00919 Uncharacterized protein family UPF0004 5 93 5.2E-22 T 11-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 PRINTS PR00720 Mammalian LMW phosphotyrosine protein phosphatase signature 29 41 3.0E-5 T 11-10-2018 IPR002115 Protein-tyrosine phosphatase, low molecular weight, mammalian GO:0003993|GO:0004726|GO:0005737|GO:0006470 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 PRINTS PR00720 Mammalian LMW phosphotyrosine protein phosphatase signature 72 87 3.0E-5 T 11-10-2018 IPR002115 Protein-tyrosine phosphatase, low molecular weight, mammalian GO:0003993|GO:0004726|GO:0005737|GO:0006470 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 PRINTS PR00720 Mammalian LMW phosphotyrosine protein phosphatase signature 89 109 3.0E-5 T 11-10-2018 IPR002115 Protein-tyrosine phosphatase, low molecular weight, mammalian GO:0003993|GO:0004726|GO:0005737|GO:0006470 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 7.2E-23 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 10 27 7.2E-23 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 86 101 7.2E-23 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 53 69 7.2E-23 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 108 121 7.2E-23 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 SMART SM00226 8 152 3.8E-51 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 150 2.0E-42 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 Gene3D G3DSA:3.40.50.2300 4 163 1.3E-66 T 11-10-2018 TO73_1305 3c959b1ac9c72bb5aa0ef117b530b82c 164 SUPERFAMILY SSF52788 5 152 5.76E-51 T 11-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TO73_1793 0a1ba08f9a2273bdbe34ec8493923b59 345 Pfam PF14332 Domain of unknown function (DUF4388) 5 158 1.0E-10 T 11-10-2018 IPR025497 Domain of unknown function DUF4388 TO73_1793 0a1ba08f9a2273bdbe34ec8493923b59 345 SUPERFAMILY SSF160246 53 108 2.88E-6 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily TO73_2208 6739838f66b8e4b16f7db66bd23179f4 323 Gene3D G3DSA:3.40.190.10 22 279 1.9E-96 T 11-10-2018 TO73_2208 6739838f66b8e4b16f7db66bd23179f4 323 Pfam PF12727 PBP superfamily domain 38 264 3.6E-38 T 11-10-2018 IPR024370 PBP domain TO73_2208 6739838f66b8e4b16f7db66bd23179f4 323 Gene3D G3DSA:3.40.190.10 101 242 1.9E-96 T 11-10-2018 TO73_2208 6739838f66b8e4b16f7db66bd23179f4 323 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 19 280 2.0E-92 T 11-10-2018 IPR011862 Phosphate binding protein GO:0042301 TO73_2208 6739838f66b8e4b16f7db66bd23179f4 323 SUPERFAMILY SSF53850 21 294 6.52E-76 T 11-10-2018 TO73_2256 bd09ad08b347374c8bf5d25bb1ac9b46 209 Gene3D G3DSA:2.102.10.10 46 208 4.2E-55 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TO73_2256 bd09ad08b347374c8bf5d25bb1ac9b46 209 PRINTS PR00162 Rieske 2Fe-2S subunit signature 149 161 7.2E-8 T 11-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TO73_2256 bd09ad08b347374c8bf5d25bb1ac9b46 209 PRINTS PR00162 Rieske 2Fe-2S subunit signature 163 175 7.2E-8 T 11-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TO73_2256 bd09ad08b347374c8bf5d25bb1ac9b46 209 PRINTS PR00162 Rieske 2Fe-2S subunit signature 127 138 7.2E-8 T 11-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TO73_2256 bd09ad08b347374c8bf5d25bb1ac9b46 209 Pfam PF00355 Rieske [2Fe-2S] domain 122 179 5.2E-12 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TO73_2256 bd09ad08b347374c8bf5d25bb1ac9b46 209 SUPERFAMILY SSF50022 58 192 1.44E-30 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TO73_1405 61aa4444581f466ec85a4188496f6762 276 SUPERFAMILY SSF53167 4 275 3.48E-84 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TO73_1405 61aa4444581f466ec85a4188496f6762 276 PIRSF PIRSF000477 2 275 1.6E-92 T 11-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TO73_1405 61aa4444581f466ec85a4188496f6762 276 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 26 272 9.5E-88 T 11-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TO73_1405 61aa4444581f466ec85a4188496f6762 276 Gene3D G3DSA:3.40.50.1580 2 274 1.6E-98 T 11-10-2018 TO73_1405 61aa4444581f466ec85a4188496f6762 276 Pfam PF01048 Phosphorylase superfamily 27 272 1.6E-42 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TO73_0418 d32bc34943fd91d4008dce56cc8121ed 296 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 201 217 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TO73_0418 d32bc34943fd91d4008dce56cc8121ed 296 Gene3D G3DSA:3.40.50.720 54 296 3.0E-78 T 11-10-2018 TO73_0418 d32bc34943fd91d4008dce56cc8121ed 296 Gene3D G3DSA:3.40.50.720 86 268 3.0E-78 T 11-10-2018 TO73_0418 d32bc34943fd91d4008dce56cc8121ed 296 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 94 261 8.6E-47 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TO73_0418 d32bc34943fd91d4008dce56cc8121ed 296 SUPERFAMILY SSF51735 88 262 2.53E-47 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_2251 af03f7cbef24b531257fd55ac775526d 395 Gene3D G3DSA:3.40.190.10 22 352 2.7E-73 T 11-10-2018 TO73_2251 af03f7cbef24b531257fd55ac775526d 395 SUPERFAMILY SSF53850 20 388 1.48E-70 T 11-10-2018 TO73_2251 af03f7cbef24b531257fd55ac775526d 395 Pfam PF13416 Bacterial extracellular solute-binding protein 37 336 3.2E-34 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein TO73_2251 af03f7cbef24b531257fd55ac775526d 395 Gene3D G3DSA:3.40.190.10 131 388 2.7E-73 T 11-10-2018 TO73_1750 a6fd72f956c5dbe6b93021d1af65e9f7 340 SUPERFAMILY SSF55729 9 149 2.54E-21 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_1750 a6fd72f956c5dbe6b93021d1af65e9f7 340 Pfam PF02388 FemAB family 219 303 6.1E-15 T 11-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 TO73_1750 a6fd72f956c5dbe6b93021d1af65e9f7 340 Pfam PF02388 FemAB family 126 206 2.0E-6 T 11-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 TO73_1750 a6fd72f956c5dbe6b93021d1af65e9f7 340 Gene3D G3DSA:3.40.630.30 121 303 5.1E-42 T 11-10-2018 TO73_1750 a6fd72f956c5dbe6b93021d1af65e9f7 340 Gene3D G3DSA:3.40.630.30 3 99 2.5E-13 T 11-10-2018 TO73_1750 a6fd72f956c5dbe6b93021d1af65e9f7 340 SUPERFAMILY SSF55729 140 313 1.87E-25 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_2411 c216e7f21a2c787c0360eca62c2c2241 225 SUPERFAMILY SSF53167 3 211 5.89E-46 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TO73_2411 c216e7f21a2c787c0360eca62c2c2241 225 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 34 215 2.0E-25 T 11-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TO73_2411 c216e7f21a2c787c0360eca62c2c2241 225 Pfam PF01048 Phosphorylase superfamily 5 218 5.8E-37 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TO73_2411 c216e7f21a2c787c0360eca62c2c2241 225 Gene3D G3DSA:3.40.50.1580 3 222 4.9E-42 T 11-10-2018 TO73_0014 20bb8edcf885658acfeb6046f887389f 155 Gene3D G3DSA:3.10.50.40 1 155 1.8E-54 T 11-10-2018 TO73_0014 20bb8edcf885658acfeb6046f887389f 155 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 132 1.8E-10 T 11-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TO73_0014 20bb8edcf885658acfeb6046f887389f 155 SUPERFAMILY SSF54534 2 136 3.14E-35 T 11-10-2018 TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 Gene3D G3DSA:2.10.230.10 128 188 1.8E-30 T 11-10-2018 TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 SUPERFAMILY SSF46565 1 90 1.96E-32 T 11-10-2018 IPR036869 Chaperone J-domain superfamily TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 SUPERFAMILY SSF57938 115 191 9.16E-14 T 11-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 Pfam PF00684 DnaJ central domain 128 188 1.1E-9 T 11-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 PRINTS PR00625 DnaJ domain signature 23 38 6.7E-22 T 11-10-2018 IPR001623 DnaJ domain TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 PRINTS PR00625 DnaJ domain signature 5 23 6.7E-22 T 11-10-2018 IPR001623 DnaJ domain TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 PRINTS PR00625 DnaJ domain signature 40 60 6.7E-22 T 11-10-2018 IPR001623 DnaJ domain TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 Pfam PF01556 DnaJ C terminal domain 102 310 1.2E-32 T 11-10-2018 IPR002939 Chaperone DnaJ, C-terminal TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 SUPERFAMILY SSF49493 96 241 1.27E-16 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 11-10-2018 IPR018253 DnaJ domain, conserved site TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 Gene3D G3DSA:2.60.260.20 98 228 1.8E-30 T 11-10-2018 TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 SMART SM00271 2 60 2.0E-32 T 11-10-2018 IPR001623 DnaJ domain TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 344 34.669 T 11-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 Gene3D G3DSA:2.60.260.20 233 332 2.8E-26 T 11-10-2018 TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 SUPERFAMILY SSF49493 238 321 6.02E-18 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 Pfam PF00226 DnaJ domain 3 65 4.5E-29 T 11-10-2018 IPR001623 DnaJ domain TO73_0238 488207986003b2e0d94e98584bfe9a2f 347 Gene3D G3DSA:1.10.287.110 1 96 1.7E-32 T 11-10-2018 IPR036869 Chaperone J-domain superfamily TO73_1223 13b4e2a4786928fb3b76d679df2aa7d8 439 Gene3D G3DSA:3.90.1310.10 41 111 9.3E-10 T 11-10-2018 TO73_1223 13b4e2a4786928fb3b76d679df2aa7d8 439 Gene3D G3DSA:3.30.450.330 112 428 1.4E-72 T 11-10-2018 TO73_1223 13b4e2a4786928fb3b76d679df2aa7d8 439 Pfam PF00905 Penicillin binding protein transpeptidase domain 140 422 9.4E-46 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TO73_1223 13b4e2a4786928fb3b76d679df2aa7d8 439 SUPERFAMILY SSF56519 59 101 1.83E-5 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TO73_1223 13b4e2a4786928fb3b76d679df2aa7d8 439 Gene3D G3DSA:3.40.710.10 171 348 1.4E-72 T 11-10-2018 TO73_1223 13b4e2a4786928fb3b76d679df2aa7d8 439 SUPERFAMILY SSF56601 110 435 5.63E-66 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TO73_1545 9284e2929a89e70213207aa02cf3f2d2 557 Gene3D G3DSA:3.30.300.310 454 557 1.5E-34 T 11-10-2018 TO73_1545 9284e2929a89e70213207aa02cf3f2d2 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 466 543 8.6E-21 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TO73_1545 9284e2929a89e70213207aa02cf3f2d2 557 SUPERFAMILY SSF56801 15 554 7.72E-170 T 11-10-2018 TO73_1545 9284e2929a89e70213207aa02cf3f2d2 557 ProSitePatterns PS00455 Putative AMP-binding domain signature. 208 219 - T 11-10-2018 IPR020845 AMP-binding, conserved site TO73_1545 9284e2929a89e70213207aa02cf3f2d2 557 Gene3D G3DSA:3.40.50.12780 12 453 2.4E-134 T 11-10-2018 TO73_1545 9284e2929a89e70213207aa02cf3f2d2 557 Pfam PF00501 AMP-binding enzyme 30 456 7.2E-121 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_2060 3b1cd45e7a97fcff5b4f6fcfc3858bf0 353 SMART SM01003 4 147 2.4E-49 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TO73_2060 3b1cd45e7a97fcff5b4f6fcfc3858bf0 353 SUPERFAMILY SSF51735 147 305 7.65E-31 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_2060 3b1cd45e7a97fcff5b4f6fcfc3858bf0 353 SUPERFAMILY SSF52283 22 333 1.11E-40 T 11-10-2018 TO73_2060 3b1cd45e7a97fcff5b4f6fcfc3858bf0 353 SMART SM01002 158 300 1.5E-42 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TO73_2060 3b1cd45e7a97fcff5b4f6fcfc3858bf0 353 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 163 330 3.1E-43 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TO73_2060 3b1cd45e7a97fcff5b4f6fcfc3858bf0 353 Gene3D G3DSA:3.40.50.720 22 332 6.6E-101 T 11-10-2018 TO73_2060 3b1cd45e7a97fcff5b4f6fcfc3858bf0 353 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 23 147 5.8E-38 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TO73_2060 3b1cd45e7a97fcff5b4f6fcfc3858bf0 353 Gene3D G3DSA:3.40.50.720 140 308 6.6E-101 T 11-10-2018 TO73_2169 b2dfbaf488b97a19d7edfd96e25acf96 308 SUPERFAMILY SSF81606 4 236 1.57E-64 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TO73_2169 b2dfbaf488b97a19d7edfd96e25acf96 308 Gene3D G3DSA:3.60.40.10 2 238 5.9E-67 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TO73_2169 b2dfbaf488b97a19d7edfd96e25acf96 308 Pfam PF13672 Protein phosphatase 2C 15 217 9.7E-19 T 11-10-2018 TO73_2169 b2dfbaf488b97a19d7edfd96e25acf96 308 SMART SM00332 1 234 1.3E-33 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TO73_2169 b2dfbaf488b97a19d7edfd96e25acf96 308 SMART SM00331 1 236 2.8E-37 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TO73_2859 32c32aac5657c0a5483721624825976f 84 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 10 68 3.4E-14 T 11-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TO73_2859 32c32aac5657c0a5483721624825976f 84 SUPERFAMILY SSF54786 8 70 2.35E-13 T 11-10-2018 TO73_2859 32c32aac5657c0a5483721624825976f 84 Gene3D G3DSA:3.30.920.30 7 75 5.1E-17 T 11-10-2018 IPR038570 HicA superfamily TO73_0836 7d8cbbb664abd5f037d45d01dd8bd19b 117 Gene3D G3DSA:1.10.10.10 3 116 1.6E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0836 7d8cbbb664abd5f037d45d01dd8bd19b 117 Pfam PF12840 Helix-turn-helix domain 10 82 2.3E-13 T 11-10-2018 TO73_0836 7d8cbbb664abd5f037d45d01dd8bd19b 117 SUPERFAMILY SSF46785 10 103 1.03E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0836 7d8cbbb664abd5f037d45d01dd8bd19b 117 SMART SM00418 9 101 1.2E-19 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_2055 e98b0942f7fa4240bc90c5d5fb04fca4 68 Pfam PF02416 mttA/Hcf106 family 1 48 3.4E-21 T 11-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TO73_2055 e98b0942f7fa4240bc90c5d5fb04fca4 68 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 67 17.689 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TO73_2055 e98b0942f7fa4240bc90c5d5fb04fca4 68 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 2 43 2.1E-20 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TO73_2833 0f00e9ce19d3930e62caf46e8cca8cc5 133 SUPERFAMILY SSF54637 13 132 1.08E-39 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_2833 0f00e9ce19d3930e62caf46e8cca8cc5 133 Pfam PF03061 Thioesterase superfamily 27 102 1.8E-21 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TO73_2833 0f00e9ce19d3930e62caf46e8cca8cc5 133 Gene3D G3DSA:3.10.129.10 10 132 4.5E-46 T 11-10-2018 TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 Pfam PF00581 Rhodanese-like domain 276 316 1.2E-5 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 Pfam PF00581 Rhodanese-like domain 374 464 2.0E-17 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 ProSitePatterns PS00380 Rhodanese signature 1. 398 409 - T 11-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 SMART SM00849 12 196 1.0E-27 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 Gene3D G3DSA:3.60.15.10 1 262 3.8E-83 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 Gene3D G3DSA:3.40.250.10 370 476 1.3E-31 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 Pfam PF00753 Metallo-beta-lactamase superfamily 13 196 2.4E-13 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 SUPERFAMILY SSF56281 4 261 8.96E-52 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 Gene3D G3DSA:3.40.250.10 266 363 1.4E-21 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 SUPERFAMILY SSF52821 239 356 3.4E-16 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 SUPERFAMILY SSF52821 370 474 2.23E-35 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 SMART SM00450 373 468 3.1E-28 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1703 f466399f0d4f6761d83a3d5005e9807b 478 SMART SM00450 272 368 0.0036 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1016 65dd0cf8e7dcae8f2645f5b20d2ba89c 366 SUPERFAMILY SSF111342 8 282 7.45E-83 T 11-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TO73_1016 65dd0cf8e7dcae8f2645f5b20d2ba89c 366 Pfam PF01888 CbiD 15 266 3.7E-88 T 11-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TO73_1016 65dd0cf8e7dcae8f2645f5b20d2ba89c 366 Gene3D G3DSA:3.30.2110.10 16 180 1.9E-50 T 11-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TO73_1016 65dd0cf8e7dcae8f2645f5b20d2ba89c 366 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 14 357 28.15 T 11-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TO73_1016 65dd0cf8e7dcae8f2645f5b20d2ba89c 366 PIRSF PIRSF026782 10 361 5.5E-114 T 11-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TO73_1016 65dd0cf8e7dcae8f2645f5b20d2ba89c 366 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 21 317 5.6E-56 T 11-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 SUPERFAMILY SSF52374 5 322 4.02E-88 T 11-10-2018 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 478 35.987 T 11-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 SUPERFAMILY SSF47323 347 477 3.14E-26 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 Pfam PF09190 DALR domain 361 417 2.0E-6 T 11-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 SMART SM00840 360 420 2.1E-6 T 11-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 322 9.5E-106 T 11-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 Gene3D G3DSA:1.20.120.640 316 477 1.7E-31 T 11-10-2018 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.8E-24 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.8E-24 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 201 219 1.8E-24 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 232 253 1.8E-24 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 476 1.8E-138 T 11-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TO73_1059 f1cf242a54ff7b6bd60ebd3c9c91fc94 480 Gene3D G3DSA:3.40.50.620 1 314 2.6E-124 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 SUPERFAMILY SSF52540 4 182 3.22E-41 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 PRINTS PR00094 Adenylate kinase signature 147 161 5.0E-36 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 PRINTS PR00094 Adenylate kinase signature 6 19 5.0E-36 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 PRINTS PR00094 Adenylate kinase signature 34 48 5.0E-36 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 PRINTS PR00094 Adenylate kinase signature 130 145 5.0E-36 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 PRINTS PR00094 Adenylate kinase signature 78 94 5.0E-36 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 Gene3D G3DSA:3.40.50.300 2 184 1.9E-64 T 11-10-2018 TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 Hamap MF_00235 Adenylate kinase [adk]. 3 183 44.247 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 Pfam PF00406 Adenylate kinase 8 160 7.5E-50 T 11-10-2018 TO73_0397 a030956f6090210dd1aeccc5f93f592b 184 ProSitePatterns PS00113 Adenylate kinase signature. 78 89 - T 11-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TO73_0920 2d3c0f784812160691ec1e919c423585 413 SUPERFAMILY SSF56601 28 405 1.59E-91 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TO73_0920 2d3c0f784812160691ec1e919c423585 413 Gene3D G3DSA:3.40.710.10 15 413 1.2E-128 T 11-10-2018 TO73_0920 2d3c0f784812160691ec1e919c423585 413 Pfam PF00144 Beta-lactamase 34 396 2.1E-69 T 11-10-2018 IPR001466 Beta-lactamase-related TO73_1543 50918a36dff825848990fdd4385016ad 125 SUPERFAMILY SSF51182 7 115 6.26E-29 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily TO73_1543 50918a36dff825848990fdd4385016ad 125 Gene3D G3DSA:2.60.120.10 7 123 2.1E-32 T 11-10-2018 IPR014710 RmlC-like jelly roll fold TO73_1543 50918a36dff825848990fdd4385016ad 125 Pfam PF07883 Cupin domain 45 112 3.8E-20 T 11-10-2018 IPR013096 Cupin 2, conserved barrel TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 7 18 - T 11-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 PRINTS PR00395 Ribosomal protein S2 signature 38 47 2.3E-40 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 PRINTS PR00395 Ribosomal protein S2 signature 197 211 2.3E-40 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 PRINTS PR00395 Ribosomal protein S2 signature 7 25 2.3E-40 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 PRINTS PR00395 Ribosomal protein S2 signature 159 176 2.3E-40 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 PRINTS PR00395 Ribosomal protein S2 signature 88 105 2.3E-40 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 PRINTS PR00395 Ribosomal protein S2 signature 176 187 2.3E-40 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 Gene3D G3DSA:1.10.287.610 98 153 6.0E-94 T 11-10-2018 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 SUPERFAMILY SSF52313 7 235 7.98E-89 T 11-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 Gene3D G3DSA:3.40.50.10490 11 216 6.0E-94 T 11-10-2018 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 Pfam PF00318 Ribosomal protein S2 10 225 5.0E-91 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 3 226 40.399 T 11-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1680 fc71c9366c795bbc4bdf6905d7612006 263 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 5 226 3.1E-96 T 11-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0224 3e36287bf7088e487c2905e8c4e16329 305 PIRSF PIRSF001359 1 305 2.5E-109 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TO73_0224 3e36287bf7088e487c2905e8c4e16329 305 Gene3D G3DSA:3.20.20.70 1 305 4.8E-137 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0224 3e36287bf7088e487c2905e8c4e16329 305 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 304 1.3E-102 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TO73_0224 3e36287bf7088e487c2905e8c4e16329 305 SUPERFAMILY SSF51569 1 305 3.96E-108 T 11-10-2018 TO73_0224 3e36287bf7088e487c2905e8c4e16329 305 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 2 305 1.3E-98 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TO73_0224 3e36287bf7088e487c2905e8c4e16329 305 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 2 305 2.0E-113 T 11-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TO73_2405 2f295664dee3b8286ecc06780b3bc17f 83 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 20 75 2.6E-8 T 11-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TO73_2405 2f295664dee3b8286ecc06780b3bc17f 83 SUPERFAMILY SSF54786 17 78 6.67E-5 T 11-10-2018 TO73_1413 bcaa12872fe3f2f6b4650a64e3cd21bb 145 Gene3D G3DSA:3.30.700.10 5 143 3.3E-5 T 11-10-2018 TO73_1413 bcaa12872fe3f2f6b4650a64e3cd21bb 145 SUPERFAMILY SSF54523 5 70 9.42E-8 T 11-10-2018 TO73_1413 bcaa12872fe3f2f6b4650a64e3cd21bb 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 25 1.2E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1413 bcaa12872fe3f2f6b4650a64e3cd21bb 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 3.4E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1413 bcaa12872fe3f2f6b4650a64e3cd21bb 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1524 3e6a575c513be2363a3f5affa83aef2b 322 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 4 320 4.7E-116 T 11-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TO73_1524 3e6a575c513be2363a3f5affa83aef2b 322 Gene3D G3DSA:3.40.190.90 123 284 4.0E-135 T 11-10-2018 TO73_1524 3e6a575c513be2363a3f5affa83aef2b 322 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 5 310 1.2E-140 T 11-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TO73_1524 3e6a575c513be2363a3f5affa83aef2b 322 SUPERFAMILY SSF56655 2 313 4.76E-110 T 11-10-2018 TO73_1524 3e6a575c513be2363a3f5affa83aef2b 322 PIRSF PIRSF004532 3 320 7.4E-137 T 11-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TO73_1524 3e6a575c513be2363a3f5affa83aef2b 322 Gene3D G3DSA:3.30.540.10 9 310 4.0E-135 T 11-10-2018 TO73_1337 050dac368201962abe25aa5b8dde3ede 174 SUPERFAMILY SSF52980 6 171 1.13E-18 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1337 050dac368201962abe25aa5b8dde3ede 174 Gene3D G3DSA:3.90.1570.10 2 172 5.3E-14 T 11-10-2018 TO73_1337 050dac368201962abe25aa5b8dde3ede 174 Pfam PF05685 Putative restriction endonuclease 10 172 2.0E-33 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_2741 7ca6b6c479d0c5bf4712144878a4888e 220 Pfam PF00565 Staphylococcal nuclease homologue 39 142 1.6E-13 T 11-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TO73_2741 7ca6b6c479d0c5bf4712144878a4888e 220 Gene3D G3DSA:2.40.50.90 25 148 9.1E-24 T 11-10-2018 IPR035437 SNase-like, OB-fold superfamily TO73_2741 7ca6b6c479d0c5bf4712144878a4888e 220 SUPERFAMILY SSF50199 26 149 1.1E-33 T 11-10-2018 TO73_2741 7ca6b6c479d0c5bf4712144878a4888e 220 SMART SM00318 18 143 9.1E-22 T 11-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TO73_0130 3ae273199f3feefd3f24671c123ff5a3 470 SUPERFAMILY SSF51395 27 417 1.67E-89 T 11-10-2018 TO73_0130 3ae273199f3feefd3f24671c123ff5a3 470 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 314 320 - T 11-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 TO73_0130 3ae273199f3feefd3f24671c123ff5a3 470 Pfam PF01070 FMN-dependent dehydrogenase 33 416 4.4E-120 T 11-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TO73_0130 3ae273199f3feefd3f24671c123ff5a3 470 Gene3D G3DSA:3.20.20.70 24 421 1.9E-126 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0235 e53eb85799480d57541b5f446aedfc95 76 Pfam PF00037 4Fe-4S binding domain 31 52 5.4E-10 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_0235 e53eb85799480d57541b5f446aedfc95 76 PRINTS PR00354 7Fe ferredoxin signature 32 49 2.0E-16 T 11-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TO73_0235 e53eb85799480d57541b5f446aedfc95 76 PRINTS PR00354 7Fe ferredoxin signature 6 16 2.0E-16 T 11-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TO73_0235 e53eb85799480d57541b5f446aedfc95 76 PRINTS PR00354 7Fe ferredoxin signature 16 26 2.0E-16 T 11-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TO73_0235 e53eb85799480d57541b5f446aedfc95 76 SUPERFAMILY SSF54862 2 73 8.66E-20 T 11-10-2018 TO73_0235 e53eb85799480d57541b5f446aedfc95 76 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 37 48 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_0235 e53eb85799480d57541b5f446aedfc95 76 Gene3D G3DSA:3.30.70.20 1 75 1.5E-32 T 11-10-2018 TO73_0887 ed37be4f4021466cffc397310559e9d5 309 Gene3D G3DSA:3.50.50.60 125 301 4.3E-24 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0887 ed37be4f4021466cffc397310559e9d5 309 Pfam PF01266 FAD dependent oxidoreductase 5 301 5.0E-34 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TO73_0887 ed37be4f4021466cffc397310559e9d5 309 Gene3D G3DSA:3.30.9.10 87 106 4.6E-18 T 11-10-2018 TO73_0887 ed37be4f4021466cffc397310559e9d5 309 Gene3D G3DSA:3.50.50.60 5 86 4.6E-18 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0887 ed37be4f4021466cffc397310559e9d5 309 Gene3D G3DSA:3.30.9.10 117 268 4.3E-24 T 11-10-2018 TO73_0887 ed37be4f4021466cffc397310559e9d5 309 SUPERFAMILY SSF51905 3 230 2.72E-24 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0054 55a6eabfeeb2848e8f3cc42c92282021 209 SMART SM00855 3 155 3.7E-25 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TO73_0054 55a6eabfeeb2848e8f3cc42c92282021 209 Gene3D G3DSA:3.40.50.1240 1 202 6.7E-58 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_0054 55a6eabfeeb2848e8f3cc42c92282021 209 PIRSF PIRSF000709 1 184 1.6E-18 T 11-10-2018 TO73_0054 55a6eabfeeb2848e8f3cc42c92282021 209 SUPERFAMILY SSF53254 1 197 5.37E-61 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_0054 55a6eabfeeb2848e8f3cc42c92282021 209 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 11-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 TO73_0054 55a6eabfeeb2848e8f3cc42c92282021 209 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 182 3.4E-57 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TO73_0453 47b7321a10b26f969472daaabb028809 121 Gene3D G3DSA:1.20.1290.10 1 114 2.6E-34 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TO73_0453 47b7321a10b26f969472daaabb028809 121 SUPERFAMILY SSF69118 3 115 1.44E-30 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TO73_0453 47b7321a10b26f969472daaabb028809 121 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 106 8.1E-20 T 11-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TO73_1770 9ccd332ebff6452335948cbb051eb4be 374 Gene3D G3DSA:3.40.50.150 180 373 6.2E-56 T 11-10-2018 TO73_1770 9ccd332ebff6452335948cbb051eb4be 374 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 235 262 - T 11-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TO73_1770 9ccd332ebff6452335948cbb051eb4be 374 Pfam PF05175 Methyltransferase small domain 198 366 4.7E-45 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TO73_1770 9ccd332ebff6452335948cbb051eb4be 374 Gene3D G3DSA:3.40.50.150 2 178 1.2E-41 T 11-10-2018 TO73_1770 9ccd332ebff6452335948cbb051eb4be 374 SUPERFAMILY SSF53335 16 146 5.57E-7 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1770 9ccd332ebff6452335948cbb051eb4be 374 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TO73_1770 9ccd332ebff6452335948cbb051eb4be 374 SMART SM00650 219 363 0.002 T 11-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TO73_1770 9ccd332ebff6452335948cbb051eb4be 374 SUPERFAMILY SSF53335 196 352 9.04E-32 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1867 aca7d79356b58bfab90418739d5a3323 335 SUPERFAMILY SSF51905 1 315 2.01E-46 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.2E-23 T 11-10-2018 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 3.2E-23 T 11-10-2018 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 3.2E-23 T 11-10-2018 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 3.2E-23 T 11-10-2018 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.2E-23 T 11-10-2018 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 Gene3D G3DSA:3.50.50.60 125 247 5.4E-118 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1867 aca7d79356b58bfab90418739d5a3323 335 Hamap MF_01685 Ferredoxin--NADP reductase. 3 328 43.032 T 11-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 3.2E-27 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 3.2E-27 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 148 172 3.2E-27 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 3.2E-27 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 3.2E-27 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_1867 aca7d79356b58bfab90418739d5a3323 335 Gene3D G3DSA:3.50.50.60 5 308 5.4E-118 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1867 aca7d79356b58bfab90418739d5a3323 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 287 3.3E-35 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TO73_2351 683a69ca73816935ce81bcc6dc29a5ae 349 Gene3D G3DSA:1.10.150.530 4 54 3.3E-10 T 11-10-2018 TO73_2351 683a69ca73816935ce81bcc6dc29a5ae 349 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 1 336 68.04 T 11-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 TO73_2351 683a69ca73816935ce81bcc6dc29a5ae 349 PIRSF PIRSF006004 2 341 8.1E-132 T 11-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 TO73_2351 683a69ca73816935ce81bcc6dc29a5ae 349 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 15 332 1.1E-111 T 11-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 TO73_2351 683a69ca73816935ce81bcc6dc29a5ae 349 Gene3D G3DSA:3.20.20.70 57 321 1.1E-98 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_2351 683a69ca73816935ce81bcc6dc29a5ae 349 SUPERFAMILY SSF102114 88 304 1.44E-17 T 11-10-2018 TO73_2351 683a69ca73816935ce81bcc6dc29a5ae 349 Pfam PF04055 Radical SAM superfamily 98 263 1.3E-17 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_1910 21e6ab65e5b7c5db0c42334a2219db40 114 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 4 110 1.9E-28 T 11-10-2018 IPR010160 CRISPR-associated protein, Cmr5 TO73_1910 21e6ab65e5b7c5db0c42334a2219db40 114 SUPERFAMILY SSF158568 1 113 1.57E-32 T 11-10-2018 IPR023101 AF1862-like domain superfamily TO73_1910 21e6ab65e5b7c5db0c42334a2219db40 114 Gene3D G3DSA:1.10.520.30 1 114 4.4E-38 T 11-10-2018 IPR023101 AF1862-like domain superfamily TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 SMART SM00306 221 320 8.1E-4 T 11-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 Gene3D G3DSA:2.170.16.10 227 319 3.6E-6 T 11-10-2018 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 SUPERFAMILY SSF52540 107 223 3.93E-21 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 PRINTS PR00379 Intein signature 277 290 1.1E-6 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 PRINTS PR00379 Intein signature 438 450 1.1E-6 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 PRINTS PR00379 Intein signature 469 484 1.1E-6 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 PRINTS PR00379 Intein signature 341 353 1.1E-6 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 PRINTS PR00379 Intein signature 573 582 1.1E-6 T 11-10-2018 IPR006142 Intein GO:0016539 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 SUPERFAMILY SSF52540 571 642 7.23E-12 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 SUPERFAMILY SSF51294 225 578 3.4E-18 T 11-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 Pfam PF14528 LAGLIDADG-like domain 438 481 6.9E-6 T 11-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 SUPERFAMILY SSF55608 421 489 2.83E-12 T 11-10-2018 IPR027434 Homing endonuclease TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 Gene3D G3DSA:3.10.28.10 320 508 3.6E-35 T 11-10-2018 IPR027434 Homing endonuclease TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 Pfam PF02562 PhoH-like protein 108 223 5.2E-50 T 11-10-2018 IPR003714 PhoH-like protein GO:0005524 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 Pfam PF02562 PhoH-like protein 579 667 1.3E-38 T 11-10-2018 IPR003714 PhoH-like protein GO:0005524 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 Gene3D G3DSA:3.40.50.300 568 667 5.9E-30 T 11-10-2018 TO73_0707 0c76f7bbfca65c8545702b05c3b7d53c 677 Gene3D G3DSA:3.40.50.300 106 226 1.6E-38 T 11-10-2018 TO73_0485 a120a35f5dea2c2ec95dbd887b487611 242 Gene3D G3DSA:3.40.1390.30 97 213 1.1E-84 T 11-10-2018 TO73_0485 a120a35f5dea2c2ec95dbd887b487611 242 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 229 5.5E-50 T 11-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TO73_0485 a120a35f5dea2c2ec95dbd887b487611 242 SUPERFAMILY SSF102705 2 241 1.28E-62 T 11-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily TO73_0485 a120a35f5dea2c2ec95dbd887b487611 242 Gene3D G3DSA:3.40.1390.30 6 230 1.1E-84 T 11-10-2018 TO73_0485 a120a35f5dea2c2ec95dbd887b487611 242 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 4 240 4.7E-45 T 11-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TO73_1155 043a1410e45444a9132209bb19dea2d9 376 Gene3D G3DSA:2.40.50.140 285 350 3.5E-25 T 11-10-2018 TO73_1155 043a1410e45444a9132209bb19dea2d9 376 SUPERFAMILY SSF52540 4 243 4.37E-88 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1155 043a1410e45444a9132209bb19dea2d9 376 Pfam PF00005 ABC transporter 20 161 1.6E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1155 043a1410e45444a9132209bb19dea2d9 376 Gene3D G3DSA:2.40.50.100 239 362 3.5E-25 T 11-10-2018 TO73_1155 043a1410e45444a9132209bb19dea2d9 376 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1155 043a1410e45444a9132209bb19dea2d9 376 Gene3D G3DSA:3.40.50.300 1 238 7.4E-75 T 11-10-2018 TO73_1155 043a1410e45444a9132209bb19dea2d9 376 SUPERFAMILY SSF50331 236 365 1.25E-30 T 11-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TO73_1155 043a1410e45444a9132209bb19dea2d9 376 SMART SM00382 28 211 9.7E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1155 043a1410e45444a9132209bb19dea2d9 376 Pfam PF03459 TOBE domain 299 355 2.9E-12 T 11-10-2018 IPR005116 Transport-associated OB, type 1 TO73_1721 3c9f140cd7b5b1872e7705f698515844 284 PIRSF PIRSF003097 1 283 4.2E-57 T 11-10-2018 IPR004513 Cell division protein FtsX GO:0016021 TO73_1721 3c9f140cd7b5b1872e7705f698515844 284 Gene3D G3DSA:3.30.70.3040 48 144 7.8E-8 T 11-10-2018 TO73_0007 6f2ead91739ceb1dca4801a57f88f2a6 204 SUPERFAMILY SSF56281 10 191 2.1E-41 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_0007 6f2ead91739ceb1dca4801a57f88f2a6 204 SMART SM00849 10 186 8.5E-30 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_0007 6f2ead91739ceb1dca4801a57f88f2a6 204 Gene3D G3DSA:3.60.15.10 4 199 9.4E-38 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_0007 6f2ead91739ceb1dca4801a57f88f2a6 204 Pfam PF00753 Metallo-beta-lactamase superfamily 12 186 4.2E-27 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_0946 3e0c7810115e8f5e62faebd83e1e2a76 303 SUPERFAMILY SSF161098 64 289 3.4E-61 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0946 3e0c7810115e8f5e62faebd83e1e2a76 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 300 1.7E-17 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0946 3e0c7810115e8f5e62faebd83e1e2a76 303 Gene3D G3DSA:1.10.3720.10 61 300 4.2E-68 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1376 a8919d329fbdb926409964cd51475a42 329 SUPERFAMILY SSF53474 38 304 3.53E-10 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_1376 a8919d329fbdb926409964cd51475a42 329 Gene3D G3DSA:3.40.50.1820 37 317 4.7E-6 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_1376 a8919d329fbdb926409964cd51475a42 329 Pfam PF03283 Pectinacetylesterase 27 203 5.7E-28 T 11-10-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 TO73_1378 4c8c53ed9125ca71838e269f43d03bbb 134 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 36 131 7.1E-22 T 11-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A TO73_1378 4c8c53ed9125ca71838e269f43d03bbb 134 Pfam PF03750 Csm2 Type III-A 19 128 8.2E-20 T 11-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A TO73_2086 12800038ac7c11c6c9ef3fdddbc1796f 259 SUPERFAMILY SSF55120 2 252 2.73E-72 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2086 12800038ac7c11c6c9ef3fdddbc1796f 259 Pfam PF01416 tRNA pseudouridine synthase 146 247 1.4E-21 T 11-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2086 12800038ac7c11c6c9ef3fdddbc1796f 259 Pfam PF01416 tRNA pseudouridine synthase 8 101 1.3E-6 T 11-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2086 12800038ac7c11c6c9ef3fdddbc1796f 259 Gene3D G3DSA:3.30.70.580 1 105 1.5E-36 T 11-10-2018 TO73_2086 12800038ac7c11c6c9ef3fdddbc1796f 259 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 246 31.496 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2086 12800038ac7c11c6c9ef3fdddbc1796f 259 PIRSF PIRSF001430 1 256 5.7E-71 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2086 12800038ac7c11c6c9ef3fdddbc1796f 259 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 240 8.5E-51 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2086 12800038ac7c11c6c9ef3fdddbc1796f 259 Gene3D G3DSA:3.30.70.660 106 249 2.7E-49 T 11-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 TO73_0085 7c0f710d430f21466297010c53e0eb09 229 Gene3D G3DSA:3.30.190.20 23 225 2.4E-88 T 11-10-2018 TO73_0085 7c0f710d430f21466297010c53e0eb09 229 PIRSF PIRSF002155 1 228 1.7E-84 T 11-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0085 7c0f710d430f21466297010c53e0eb09 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.0E-99 T 11-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TO73_0085 7c0f710d430f21466297010c53e0eb09 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.104 T 11-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TO73_0085 7c0f710d430f21466297010c53e0eb09 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 140 - T 11-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0085 7c0f710d430f21466297010c53e0eb09 229 Pfam PF00687 Ribosomal protein L1p/L10e family 31 221 5.0E-54 T 11-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TO73_0085 7c0f710d430f21466297010c53e0eb09 229 Gene3D G3DSA:3.40.50.790 68 160 2.4E-88 T 11-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TO73_0085 7c0f710d430f21466297010c53e0eb09 229 SUPERFAMILY SSF56808 6 227 1.57E-84 T 11-10-2018 IPR023674 Ribosomal protein L1-like TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 Pfam PF01479 S4 domain 4 49 2.3E-14 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 Gene3D G3DSA:3.10.290.10 1 57 6.6E-21 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 SUPERFAMILY SSF55120 62 228 4.32E-37 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 68 221 2.6E-41 T 11-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 Pfam PF00849 RNA pseudouridylate synthase 64 190 1.0E-14 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 SUPERFAMILY SSF55174 4 93 3.24E-20 T 11-10-2018 TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 11-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 Gene3D G3DSA:3.30.70.1560 124 210 4.5E-48 T 11-10-2018 TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 Gene3D G3DSA:3.30.70.580 66 218 4.5E-48 T 11-10-2018 TO73_2021 39a8a5db98c1bbe3b5d8abd2f13c71fd 235 SMART SM00363 4 64 5.9E-15 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 Gene3D G3DSA:3.20.190.10 2 121 2.2E-38 T 11-10-2018 IPR035937 MutM-like, N-terminal TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 263 4.1E-82 T 11-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 SUPERFAMILY SSF81624 2 124 4.06E-32 T 11-10-2018 IPR035937 MutM-like, N-terminal TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 Gene3D G3DSA:1.10.8.50 122 259 8.4E-52 T 11-10-2018 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 Pfam PF06827 Zinc finger found in FPG and IleRS 236 263 3.1E-6 T 11-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 SUPERFAMILY SSF57716 213 263 8.76E-16 T 11-10-2018 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 264 39.558 T 11-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 211 4.2E-27 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 SMART SM01232 122 214 1.0E-44 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 SUPERFAMILY SSF46946 121 211 3.39E-30 T 11-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 105 1.6E-25 T 11-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TO73_0330 fbba69050a0289f6ec37f899ba96f7af 264 SMART SM00898 2 106 2.3E-34 T 11-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TO73_1655 0e9b60b1c0b694219c3bc56677a6e6dd 184 SUPERFAMILY SSF52980 6 176 1.98E-22 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1655 0e9b60b1c0b694219c3bc56677a6e6dd 184 Gene3D G3DSA:3.90.1570.10 3 180 2.3E-16 T 11-10-2018 TO73_1655 0e9b60b1c0b694219c3bc56677a6e6dd 184 Pfam PF05685 Putative restriction endonuclease 12 160 4.4E-24 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_0600 8b6749a1de30487e2f0f918e9eeed670 259 SUPERFAMILY SSF52540 3 251 4.1E-68 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0600 8b6749a1de30487e2f0f918e9eeed670 259 SMART SM00382 28 228 2.4E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0600 8b6749a1de30487e2f0f918e9eeed670 259 Pfam PF00005 ABC transporter 20 179 1.5E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0600 8b6749a1de30487e2f0f918e9eeed670 259 Gene3D G3DSA:3.40.50.300 1 252 7.8E-66 T 11-10-2018 TO73_0600 8b6749a1de30487e2f0f918e9eeed670 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 251 1.1E-13 T 11-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TO73_2049 b364131d2f1138709aeacd656270e910 118 Pfam PF04892 VanZ like family 39 104 9.0E-10 T 11-10-2018 IPR006976 VanZ-like TO73_1566 22dacea3244708d06311358cd72b0b7a 827 Pfam PF04851 Type III restriction enzyme, res subunit 1 248 5.9E-13 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TO73_1566 22dacea3244708d06311358cd72b0b7a 827 SUPERFAMILY SSF52540 57 408 9.42E-13 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1566 22dacea3244708d06311358cd72b0b7a 827 Gene3D G3DSA:3.40.50.300 333 437 7.5E-11 T 11-10-2018 TO73_0736 0b93f9c5c5842304347375a596f3e475 385 Pfam PF07690 Major Facilitator Superfamily 11 195 3.6E-27 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_0736 0b93f9c5c5842304347375a596f3e475 385 Pfam PF07690 Major Facilitator Superfamily 215 380 5.1E-21 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_0736 0b93f9c5c5842304347375a596f3e475 385 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 77 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TO73_0736 0b93f9c5c5842304347375a596f3e475 385 Gene3D G3DSA:1.20.1250.20 5 187 6.5E-30 T 11-10-2018 TO73_0736 0b93f9c5c5842304347375a596f3e475 385 Gene3D G3DSA:1.20.1250.20 204 384 5.4E-25 T 11-10-2018 TO73_0736 0b93f9c5c5842304347375a596f3e475 385 SUPERFAMILY SSF103473 6 378 8.37E-64 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_1779 99082372bcb84a70c48d39ec0d1214e5 349 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 258 342 2.3E-17 T 11-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TO73_1779 99082372bcb84a70c48d39ec0d1214e5 349 Pfam PF01571 Aminomethyltransferase folate-binding domain 6 253 2.0E-87 T 11-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TO73_1779 99082372bcb84a70c48d39ec0d1214e5 349 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 347 7.8E-104 T 11-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TO73_1779 99082372bcb84a70c48d39ec0d1214e5 349 SUPERFAMILY SSF103025 1 267 1.26E-95 T 11-10-2018 TO73_1779 99082372bcb84a70c48d39ec0d1214e5 349 Gene3D G3DSA:3.30.1360.120 1 346 5.7E-124 T 11-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TO73_1779 99082372bcb84a70c48d39ec0d1214e5 349 PIRSF PIRSF006487 1 349 9.3E-82 T 11-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TO73_1779 99082372bcb84a70c48d39ec0d1214e5 349 SUPERFAMILY SSF101790 266 347 9.16E-21 T 11-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TO73_1779 99082372bcb84a70c48d39ec0d1214e5 349 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 348 39.507 T 11-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TO73_2506 f9a274b53eff78dc21b050d0b0b8ae3d 374 SUPERFAMILY SSF53098 18 364 1.37E-45 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2506 f9a274b53eff78dc21b050d0b0b8ae3d 374 Gene3D G3DSA:3.90.350.10 45 293 4.1E-26 T 11-10-2018 IPR014736 Transposase, Tn5-like, core TO73_2506 f9a274b53eff78dc21b050d0b0b8ae3d 374 Pfam PF01609 Transposase DDE domain 147 302 1.2E-14 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_1089 f9a274b53eff78dc21b050d0b0b8ae3d 374 SUPERFAMILY SSF53098 18 364 1.37E-45 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_1089 f9a274b53eff78dc21b050d0b0b8ae3d 374 Gene3D G3DSA:3.90.350.10 45 293 4.1E-26 T 11-10-2018 IPR014736 Transposase, Tn5-like, core TO73_1089 f9a274b53eff78dc21b050d0b0b8ae3d 374 Pfam PF01609 Transposase DDE domain 147 302 1.2E-14 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_2364 88dfd9ab184ae51b506022868205d95e 239 Gene3D G3DSA:3.40.50.300 1 237 7.4E-65 T 11-10-2018 TO73_2364 88dfd9ab184ae51b506022868205d95e 239 SMART SM00382 26 209 1.5E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2364 88dfd9ab184ae51b506022868205d95e 239 SUPERFAMILY SSF52540 2 223 2.97E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2364 88dfd9ab184ae51b506022868205d95e 239 Pfam PF00005 ABC transporter 18 161 2.6E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1070 59958bda3a22850d2f01f82fd0c1ddfd 390 Pfam PF07690 Major Facilitator Superfamily 216 380 1.9E-13 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_1070 59958bda3a22850d2f01f82fd0c1ddfd 390 SUPERFAMILY SSF103473 16 382 9.94E-38 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_1070 59958bda3a22850d2f01f82fd0c1ddfd 390 Gene3D G3DSA:1.20.1250.20 206 385 3.0E-19 T 11-10-2018 TO73_1070 59958bda3a22850d2f01f82fd0c1ddfd 390 Gene3D G3DSA:1.20.1250.20 12 201 4.1E-10 T 11-10-2018 TO73_0674 ea524faa733dd504a049d3c3479b810a 320 Gene3D G3DSA:1.20.1600.10 210 319 3.1E-11 T 11-10-2018 TO73_0674 ea524faa733dd504a049d3c3479b810a 320 Gene3D G3DSA:1.20.1600.10 49 209 3.1E-19 T 11-10-2018 TO73_0674 ea524faa733dd504a049d3c3479b810a 320 Pfam PF02321 Outer membrane efflux protein 212 317 2.5E-9 T 11-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TO73_0674 ea524faa733dd504a049d3c3479b810a 320 Pfam PF02321 Outer membrane efflux protein 62 163 4.5E-12 T 11-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TO73_0674 ea524faa733dd504a049d3c3479b810a 320 SUPERFAMILY SSF56954 38 318 4.71E-32 T 11-10-2018 TO73_1641 8728ddfd26b940939931e96ae279c7ad 255 Pfam PF15461 Beta-carotene 15,15'-dioxygenase 24 240 1.0E-20 T 11-10-2018 IPR022270 Beta-carotene 15,15'-monooxygenase, Brp/Blh family GO:0016702|GO:0055114 KEGG: 00830+1.13.11.63|MetaCyc: PWY-6857 TO73_1641 8728ddfd26b940939931e96ae279c7ad 255 TIGRFAM TIGR03753 blh_monoox: beta-carotene 15,15'-monooxygenase, Brp/Blh family 21 237 1.7E-36 T 11-10-2018 IPR022270 Beta-carotene 15,15'-monooxygenase, Brp/Blh family GO:0016702|GO:0055114 KEGG: 00830+1.13.11.63|MetaCyc: PWY-6857 TO73_0696 473003a02c460fea3db518a37b28552b 706 SUPERFAMILY SSF52317 248 569 3.51E-18 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0696 473003a02c460fea3db518a37b28552b 706 SUPERFAMILY SSF53300 307 472 1.0E-29 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TO73_0696 473003a02c460fea3db518a37b28552b 706 Pfam PF00092 von Willebrand factor type A domain 309 469 3.5E-16 T 11-10-2018 IPR002035 von Willebrand factor, type A TO73_0696 473003a02c460fea3db518a37b28552b 706 SMART SM00327 306 478 2.0E-26 T 11-10-2018 IPR002035 von Willebrand factor, type A TO73_0696 473003a02c460fea3db518a37b28552b 706 Gene3D G3DSA:3.40.50.410 306 474 8.4E-37 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TO73_0947 28f4550140dd32473382291b74cce611 245 Pfam PF01261 Xylose isomerase-like TIM barrel 70 202 2.7E-13 T 11-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TO73_0947 28f4550140dd32473382291b74cce611 245 SUPERFAMILY SSF51658 46 231 5.63E-27 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily TO73_0947 28f4550140dd32473382291b74cce611 245 Gene3D G3DSA:3.20.20.150 1 242 2.1E-56 T 11-10-2018 TO73_0670 9bd2e9f5a66ec80a78c3ae3fe352fb0a 325 Gene3D G3DSA:3.40.91.100 166 322 7.9E-11 T 11-10-2018 TO73_0670 9bd2e9f5a66ec80a78c3ae3fe352fb0a 325 Pfam PF04471 Restriction endonuclease 193 314 1.2E-21 T 11-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 TO73_0670 9bd2e9f5a66ec80a78c3ae3fe352fb0a 325 SUPERFAMILY SSF52980 196 318 2.25E-9 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_0692 77f353302099b42046a0abab472140a3 521 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 272 350 1.8E-12 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_0692 77f353302099b42046a0abab472140a3 521 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 19 94 1.0E-17 T 11-10-2018 IPR010094 Transposase (putative), N-terminal TO73_1256 7076aa021e0330d41782fa3a6f347c1a 335 SUPERFAMILY SSF51395 25 328 3.42E-68 T 11-10-2018 TO73_1256 7076aa021e0330d41782fa3a6f347c1a 335 PIRSF PIRSF003314 2 332 9.2E-108 T 11-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TO73_1256 7076aa021e0330d41782fa3a6f347c1a 335 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 325 4.3E-102 T 11-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TO73_1256 7076aa021e0330d41782fa3a6f347c1a 335 Pfam PF01070 FMN-dependent dehydrogenase 171 322 2.9E-17 T 11-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TO73_1256 7076aa021e0330d41782fa3a6f347c1a 335 Pfam PF01070 FMN-dependent dehydrogenase 7 96 1.3E-9 T 11-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TO73_1256 7076aa021e0330d41782fa3a6f347c1a 335 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 332 33.872 T 11-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TO73_1256 7076aa021e0330d41782fa3a6f347c1a 335 SMART SM01240 36 334 0.0085 T 11-10-2018 TO73_1256 7076aa021e0330d41782fa3a6f347c1a 335 Gene3D G3DSA:3.20.20.70 2 331 2.3E-110 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0782 7d1cbb11a017146e9732b55ea3d3e285 298 SUPERFAMILY SSF51182 5 203 1.53E-51 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily TO73_0782 7d1cbb11a017146e9732b55ea3d3e285 298 Gene3D G3DSA:2.60.120.10 25 166 1.6E-45 T 11-10-2018 IPR014710 RmlC-like jelly roll fold TO73_1429 6620d8b3c60ae03a1e118ab02c8dca27 345 Gene3D G3DSA:3.40.718.10 1 345 1.2E-156 T 11-10-2018 TO73_1429 6620d8b3c60ae03a1e118ab02c8dca27 345 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 2 343 6.4E-162 T 11-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 TO73_1429 6620d8b3c60ae03a1e118ab02c8dca27 345 SMART SM01329 2 340 3.0E-187 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TO73_1429 6620d8b3c60ae03a1e118ab02c8dca27 345 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 340 4.9E-130 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TO73_1429 6620d8b3c60ae03a1e118ab02c8dca27 345 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 237 256 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TO73_1429 6620d8b3c60ae03a1e118ab02c8dca27 345 SUPERFAMILY SSF53659 2 344 6.48E-120 T 11-10-2018 TO73_1429 6620d8b3c60ae03a1e118ab02c8dca27 345 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 1 344 47.129 T 11-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 TO73_0968 ed8b9fc6a04179bdbbee8386de4b8cd8 191 Gene3D G3DSA:1.10.357.10 47 189 3.8E-40 T 11-10-2018 TO73_0968 ed8b9fc6a04179bdbbee8386de4b8cd8 191 Gene3D G3DSA:1.10.10.60 2 45 2.3E-23 T 11-10-2018 TO73_0968 ed8b9fc6a04179bdbbee8386de4b8cd8 191 SUPERFAMILY SSF46689 4 76 1.56E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_0968 ed8b9fc6a04179bdbbee8386de4b8cd8 191 SUPERFAMILY SSF48498 79 186 7.97E-26 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TO73_0968 ed8b9fc6a04179bdbbee8386de4b8cd8 191 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TO73_0968 ed8b9fc6a04179bdbbee8386de4b8cd8 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 1.6E-18 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_0968 ed8b9fc6a04179bdbbee8386de4b8cd8 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.4E-13 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_0968 ed8b9fc6a04179bdbbee8386de4b8cd8 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.4E-13 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_0628 1493f474c729097e358040cac2c19ec3 252 Pfam PF09339 IclR helix-turn-helix domain 14 62 3.9E-14 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TO73_0628 1493f474c729097e358040cac2c19ec3 252 Gene3D G3DSA:1.10.10.10 6 79 1.6E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0628 1493f474c729097e358040cac2c19ec3 252 SUPERFAMILY SSF55781 67 248 2.22E-52 T 11-10-2018 TO73_0628 1493f474c729097e358040cac2c19ec3 252 SUPERFAMILY SSF46785 12 82 1.66E-14 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0628 1493f474c729097e358040cac2c19ec3 252 Gene3D G3DSA:3.30.450.40 80 251 5.8E-58 T 11-10-2018 IPR029016 GAF-like domain superfamily TO73_0628 1493f474c729097e358040cac2c19ec3 252 Pfam PF01614 Bacterial transcriptional regulator 130 243 2.0E-34 T 11-10-2018 IPR014757 Transcription regulator IclR, C-terminal TO73_0628 1493f474c729097e358040cac2c19ec3 252 SMART SM00346 12 98 6.1E-24 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 Gene3D G3DSA:3.10.580.10 312 445 1.6E-10 T 11-10-2018 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 Gene3D G3DSA:3.90.1640.10 16 189 8.5E-26 T 11-10-2018 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 Gene3D G3DSA:3.30.460.10 456 595 2.0E-32 T 11-10-2018 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 Pfam PF01743 Poly A polymerase head domain 474 600 1.8E-21 T 11-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 SUPERFAMILY SSF54631 315 438 1.52E-12 T 11-10-2018 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 Pfam PF01368 DHH family 17 157 6.4E-8 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 SUPERFAMILY SSF81301 464 597 5.99E-27 T 11-10-2018 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 SMART SM00116 325 377 0.0084 T 11-10-2018 IPR000644 CBS domain TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 SMART SM00116 391 441 4.5 T 11-10-2018 IPR000644 CBS domain TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 Pfam PF00571 CBS domain 320 375 5.0E-7 T 11-10-2018 IPR000644 CBS domain TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 Pfam PF00571 CBS domain 393 439 0.0015 T 11-10-2018 IPR000644 CBS domain TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 SUPERFAMILY SSF64182 17 298 1.11E-42 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 SUPERFAMILY SSF81891 599 822 1.96E-23 T 11-10-2018 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 Gene3D G3DSA:1.10.3090.10 596 821 1.6E-27 T 11-10-2018 TO73_1662 dbe04ea9de1069792db9ef511b73f136 833 Pfam PF02272 DHHA1 domain 207 299 3.8E-6 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TO73_2163 79af252d3225def6fe5e2aa116d784e0 304 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 201 276 3.5E-21 T 11-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal TO73_2163 79af252d3225def6fe5e2aa116d784e0 304 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 16 299 1.3E-131 T 11-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate TO73_2163 79af252d3225def6fe5e2aa116d784e0 304 SUPERFAMILY SSF52518 14 276 1.69E-74 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold TO73_2163 79af252d3225def6fe5e2aa116d784e0 304 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 197 6.3E-27 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TO73_2163 79af252d3225def6fe5e2aa116d784e0 304 Gene3D G3DSA:3.40.50.970 25 201 2.2E-21 T 11-10-2018 TO73_2114 885c2a705e4e9be3a51132635bb64511 303 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 284 1.7E-42 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_0086 ac00676750aacb34fde92c0a69377b8d 173 SUPERFAMILY SSF160369 4 171 1.1E-45 T 11-10-2018 TO73_0086 ac00676750aacb34fde92c0a69377b8d 173 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 3 143 8.0E-9 T 11-10-2018 TO73_0086 ac00676750aacb34fde92c0a69377b8d 173 Pfam PF00466 Ribosomal protein L10 4 98 2.7E-21 T 11-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TO73_0086 ac00676750aacb34fde92c0a69377b8d 173 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 2 160 21.181 T 11-10-2018 IPR022973 Ribosomal protein L10 TO73_0086 ac00676750aacb34fde92c0a69377b8d 173 Gene3D G3DSA:3.30.70.1730 2 133 4.8E-40 T 11-10-2018 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 320 38.807 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 84 95 - T 11-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 Pfam PF07478 D-ala D-ala ligase C-terminus 125 317 3.6E-65 T 11-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 SUPERFAMILY SSF52440 2 116 2.01E-28 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TO73_1801 4258bcb8c8f90986e398883efb34d438 321 Pfam PF01820 D-ala D-ala ligase N-terminus 4 106 8.6E-22 T 11-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 PIRSF PIRSF039102 1 67 8.9E-7 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 PIRSF PIRSF039102 70 321 1.9E-88 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 319 1.4E-96 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 Gene3D G3DSA:3.30.470.20 112 318 5.7E-83 T 11-10-2018 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 SUPERFAMILY SSF56059 117 320 1.06E-56 T 11-10-2018 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 Gene3D G3DSA:3.40.50.20 3 106 4.0E-35 T 11-10-2018 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 Gene3D G3DSA:3.30.1490.20 134 190 5.7E-83 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TO73_1801 4258bcb8c8f90986e398883efb34d438 321 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 263 290 - T 11-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 SMART SM00387 308 412 4.7E-38 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 Pfam PF00512 His Kinase A (phospho-acceptor) domain 214 272 8.8E-15 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 SUPERFAMILY SSF55874 263 410 3.54E-34 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 SUPERFAMILY SSF47384 195 272 1.33E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 9.6E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 9.6E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 9.6E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 409 9.6E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 Gene3D G3DSA:1.10.287.130 162 273 3.2E-19 T 11-10-2018 TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 410 4.6E-24 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 SMART SM00388 212 274 1.3E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_0577 8f219a7f8f5c43205a6aa21364b08769 414 Gene3D G3DSA:3.30.565.10 275 413 3.1E-34 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_2148 465ef7157108222cee0f9573b8c0767c 226 Pfam PF00005 ABC transporter 21 150 3.8E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_2148 465ef7157108222cee0f9573b8c0767c 226 Gene3D G3DSA:3.40.50.300 12 212 7.0E-52 T 11-10-2018 TO73_2148 465ef7157108222cee0f9573b8c0767c 226 SMART SM00382 21 194 3.1E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2148 465ef7157108222cee0f9573b8c0767c 226 SUPERFAMILY SSF52540 21 208 3.51E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2148 465ef7157108222cee0f9573b8c0767c 226 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1557 cd887dc0896a27ec61e4907a3ab8f87c 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 176 9.4E-53 T 11-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TO73_1557 cd887dc0896a27ec61e4907a3ab8f87c 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 11-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TO73_1557 cd887dc0896a27ec61e4907a3ab8f87c 194 Gene3D G3DSA:3.30.230.40 91 194 1.9E-31 T 11-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TO73_1557 cd887dc0896a27ec61e4907a3ab8f87c 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 36.05 T 11-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TO73_1557 cd887dc0896a27ec61e4907a3ab8f87c 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 11-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TO73_1557 cd887dc0896a27ec61e4907a3ab8f87c 194 Gene3D G3DSA:3.30.230.40 1 90 1.1E-28 T 11-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TO73_1557 cd887dc0896a27ec61e4907a3ab8f87c 194 SUPERFAMILY SSF54211 2 84 1.64E-25 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_1557 cd887dc0896a27ec61e4907a3ab8f87c 194 SUPERFAMILY SSF54211 87 181 7.08E-26 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0890 726c43daf2b62c3408ee78cbcda254d6 594 Gene3D G3DSA:1.50.10.10 215 587 5.4E-50 T 11-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TO73_0890 726c43daf2b62c3408ee78cbcda254d6 594 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 5 174 4.3E-19 T 11-10-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal TO73_0890 726c43daf2b62c3408ee78cbcda254d6 594 SUPERFAMILY SSF48208 218 584 2.87E-69 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TO73_0890 726c43daf2b62c3408ee78cbcda254d6 594 Pfam PF06202 Amylo-alpha-1,6-glucosidase 224 581 9.9E-11 T 11-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 TO73_2816 9c867baa95de0100ea96cb28113688be 49 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 45 3.2E-9 T 11-10-2018 IPR025161 Putative transposase IS4/IS5 family TO73_2073 7f149c2d18ea0359767aa8e19b088d13 315 SUPERFAMILY SSF52172 2 133 1.85E-41 T 11-10-2018 IPR011006 CheY-like superfamily TO73_2073 7f149c2d18ea0359767aa8e19b088d13 315 Pfam PF00072 Response regulator receiver domain 3 112 7.0E-29 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_2073 7f149c2d18ea0359767aa8e19b088d13 315 TIGRFAM TIGR00277 HDIG: HDIG domain 149 236 1.2E-7 T 11-10-2018 IPR006675 HDIG domain TO73_2073 7f149c2d18ea0359767aa8e19b088d13 315 Gene3D G3DSA:3.40.50.2300 1 131 1.9E-40 T 11-10-2018 TO73_2073 7f149c2d18ea0359767aa8e19b088d13 315 SUPERFAMILY SSF109604 138 291 7.54E-34 T 11-10-2018 TO73_2073 7f149c2d18ea0359767aa8e19b088d13 315 Pfam PF01966 HD domain 149 265 8.2E-13 T 11-10-2018 IPR006674 HD domain TO73_2073 7f149c2d18ea0359767aa8e19b088d13 315 SMART SM00448 1 112 9.3E-36 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_2073 7f149c2d18ea0359767aa8e19b088d13 315 Gene3D G3DSA:1.10.3210.10 132 310 8.8E-52 T 11-10-2018 TO73_2073 7f149c2d18ea0359767aa8e19b088d13 315 SMART SM00471 142 275 2.2E-11 T 11-10-2018 IPR003607 HD/PDEase domain TO73_0554 b07c2f4053bf4405758a5f588764ef86 756 Gene3D G3DSA:3.30.1370.120 446 535 2.9E-18 T 11-10-2018 IPR038591 NolW-like superfamily TO73_0554 b07c2f4053bf4405758a5f588764ef86 756 Pfam PF03958 Bacterial type II/III secretion system short domain 391 449 1.3E-7 T 11-10-2018 IPR005644 NolW-like TO73_0554 b07c2f4053bf4405758a5f588764ef86 756 Pfam PF03958 Bacterial type II/III secretion system short domain 456 533 1.9E-18 T 11-10-2018 IPR005644 NolW-like TO73_0554 b07c2f4053bf4405758a5f588764ef86 756 PRINTS PR00811 Bacterial general secretion pathway protein D signature 737 751 6.2E-7 T 11-10-2018 IPR001775 GspD/PilQ family TO73_0554 b07c2f4053bf4405758a5f588764ef86 756 PRINTS PR00811 Bacterial general secretion pathway protein D signature 714 732 6.2E-7 T 11-10-2018 IPR001775 GspD/PilQ family TO73_0554 b07c2f4053bf4405758a5f588764ef86 756 PRINTS PR00811 Bacterial general secretion pathway protein D signature 470 480 6.2E-7 T 11-10-2018 IPR001775 GspD/PilQ family TO73_0554 b07c2f4053bf4405758a5f588764ef86 756 Pfam PF00263 Bacterial type II and III secretion system protein 593 750 1.0E-37 T 11-10-2018 IPR004846 Type II/III secretion system GO:0009306 TO73_0438 d4f37913bbfa9e5e58b78e604a007b08 71 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 42 70 0.0026 T 11-10-2018 TO73_1773 973b790f5a2ae52068c3f2fcedf23a6d 457 Pfam PF07969 Amidohydrolase family 32 441 3.4E-57 T 11-10-2018 IPR013108 Amidohydrolase 3 TO73_1773 973b790f5a2ae52068c3f2fcedf23a6d 457 SUPERFAMILY SSF51556 34 427 4.3E-32 T 11-10-2018 IPR032466 Metal-dependent hydrolase TO73_1773 973b790f5a2ae52068c3f2fcedf23a6d 457 Gene3D G3DSA:3.20.20.140 35 427 1.8E-82 T 11-10-2018 TO73_1773 973b790f5a2ae52068c3f2fcedf23a6d 457 Gene3D G3DSA:2.30.40.10 31 440 1.8E-82 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TO73_1773 973b790f5a2ae52068c3f2fcedf23a6d 457 Gene3D G3DSA:3.10.310.70 53 164 1.8E-82 T 11-10-2018 TO73_0059 b36c83a8bfe7cd49cbedf7800d490d96 160 Gene3D G3DSA:3.40.50.1000 17 141 1.2E-15 T 11-10-2018 IPR023214 HAD superfamily TO73_0059 b36c83a8bfe7cd49cbedf7800d490d96 160 Pfam PF13242 HAD-hyrolase-like 93 131 4.9E-8 T 11-10-2018 TO73_0059 b36c83a8bfe7cd49cbedf7800d490d96 160 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 2 152 5.7E-35 T 11-10-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like TO73_0059 b36c83a8bfe7cd49cbedf7800d490d96 160 SUPERFAMILY SSF56784 4 132 6.02E-20 T 11-10-2018 IPR036412 HAD-like superfamily TO73_1000 2249e8a261d468fe9d740802c34453b9 319 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 231 252 - T 11-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 TO73_1000 2249e8a261d468fe9d740802c34453b9 319 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 45 1.5E-4 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TO73_1000 2249e8a261d468fe9d740802c34453b9 319 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 136 253 6.4E-15 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TO73_1000 2249e8a261d468fe9d740802c34453b9 319 SUPERFAMILY SSF54593 1 261 1.43E-45 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_1000 2249e8a261d468fe9d740802c34453b9 319 Gene3D G3DSA:3.10.180.10 136 294 2.7E-46 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_1000 2249e8a261d468fe9d740802c34453b9 319 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 3 294 1.6E-133 T 11-10-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type TO73_1000 2249e8a261d468fe9d740802c34453b9 319 Gene3D G3DSA:3.10.180.10 1 133 7.4E-30 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_2139 cef870fd6b15a2fae13ecfbf5f84238d 977 Gene3D G3DSA:2.60.40.1190 551 732 2.4E-6 T 11-10-2018 TO73_2139 cef870fd6b15a2fae13ecfbf5f84238d 977 SUPERFAMILY SSF49344 747 971 1.22E-67 T 11-10-2018 TO73_2139 cef870fd6b15a2fae13ecfbf5f84238d 977 Pfam PF03065 Glycosyl hydrolase family 57 24 461 5.5E-94 T 11-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TO73_2139 cef870fd6b15a2fae13ecfbf5f84238d 977 SUPERFAMILY SSF49344 553 717 1.8E-6 T 11-10-2018 TO73_2139 cef870fd6b15a2fae13ecfbf5f84238d 977 Gene3D G3DSA:3.20.110.20 158 506 3.1E-31 T 11-10-2018 TO73_2139 cef870fd6b15a2fae13ecfbf5f84238d 977 Gene3D G3DSA:2.60.40.1190 744 971 2.3E-60 T 11-10-2018 TO73_2139 cef870fd6b15a2fae13ecfbf5f84238d 977 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 748 968 2.2E-69 T 11-10-2018 IPR019248 Glucodextranase-like, C-terminal TO73_2139 cef870fd6b15a2fae13ecfbf5f84238d 977 SUPERFAMILY SSF88713 19 448 4.08E-85 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TO73_2075 349f1e58775cc9347775f39d3bf4a960 311 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 192 25.763 T 11-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 TO73_2075 349f1e58775cc9347775f39d3bf4a960 311 Gene3D G3DSA:3.40.50.150 6 197 1.9E-48 T 11-10-2018 TO73_2075 349f1e58775cc9347775f39d3bf4a960 311 Pfam PF02390 Putative methyltransferase 23 186 7.6E-37 T 11-10-2018 TO73_2075 349f1e58775cc9347775f39d3bf4a960 311 SUPERFAMILY SSF53335 19 190 1.21E-25 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2075 349f1e58775cc9347775f39d3bf4a960 311 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 18 157 7.0E-34 T 11-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 TO73_1687 ef3cfd0c755508da00026cfcf4a0ff2f 208 SUPERFAMILY SSF53448 4 170 1.97E-31 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1687 ef3cfd0c755508da00026cfcf4a0ff2f 208 Gene3D G3DSA:3.90.550.10 2 208 8.0E-34 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1687 ef3cfd0c755508da00026cfcf4a0ff2f 208 Pfam PF00535 Glycosyl transferase family 2 4 137 9.9E-22 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TO73_0792 9ee9c29afff9a1044c240b86fe58b4c2 100 SUPERFAMILY SSF81301 12 97 3.54E-15 T 11-10-2018 TO73_0792 9ee9c29afff9a1044c240b86fe58b4c2 100 Pfam PF01909 Nucleotidyltransferase domain 20 77 2.9E-8 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TO73_0792 9ee9c29afff9a1044c240b86fe58b4c2 100 Gene3D G3DSA:3.30.460.10 5 100 3.8E-20 T 11-10-2018 TO73_2094 4287e895b997cc0d4bd76568bc869bbf 195 SUPERFAMILY SSF117396 21 136 4.45E-8 T 11-10-2018 IPR036520 UPF0759 superfamily TO73_2094 4287e895b997cc0d4bd76568bc869bbf 195 Pfam PF01904 Protein of unknown function DUF72 33 134 7.0E-8 T 11-10-2018 IPR002763 Protein of unknown function DUF72 TO73_2094 4287e895b997cc0d4bd76568bc869bbf 195 Gene3D G3DSA:3.20.20.410 15 142 6.0E-7 T 11-10-2018 IPR036520 UPF0759 superfamily TO73_2149 36796832968256dfa9d19c08cc1ac361 234 Pfam PF05573 NosL 53 189 7.8E-12 T 11-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL TO73_2149 36796832968256dfa9d19c08cc1ac361 234 SUPERFAMILY SSF160387 102 188 8.11E-12 T 11-10-2018 TO73_1224 600f4b8e303b5e23e77e73839650fa8e 420 Gene3D G3DSA:3.40.1190.10 76 289 4.9E-32 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_1224 600f4b8e303b5e23e77e73839650fa8e 420 SUPERFAMILY SSF53623 95 288 1.1E-24 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_1224 600f4b8e303b5e23e77e73839650fa8e 420 Pfam PF01225 Mur ligase family, catalytic domain 28 68 8.2E-6 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TO73_1224 600f4b8e303b5e23e77e73839650fa8e 420 SUPERFAMILY SSF53244 292 417 5.95E-28 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_1224 600f4b8e303b5e23e77e73839650fa8e 420 Pfam PF02875 Mur ligase family, glutamate ligase domain 292 361 3.1E-11 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TO73_1224 600f4b8e303b5e23e77e73839650fa8e 420 Pfam PF08245 Mur ligase middle domain 99 271 2.0E-12 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TO73_1224 600f4b8e303b5e23e77e73839650fa8e 420 Gene3D G3DSA:3.90.190.20 291 420 1.4E-32 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_1224 600f4b8e303b5e23e77e73839650fa8e 420 SUPERFAMILY SSF63418 4 90 2.09E-15 T 11-10-2018 IPR035911 MurE/MurF, N-terminal TO73_1224 600f4b8e303b5e23e77e73839650fa8e 420 Gene3D G3DSA:3.40.1390.10 2 75 2.6E-10 T 11-10-2018 TO73_0629 8162ef4a25973b656a03abbd89478952 225 SMART SM00422 2 71 2.2E-25 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TO73_0629 8162ef4a25973b656a03abbd89478952 225 SMART SM00422 121 190 2.2E-25 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TO73_0629 8162ef4a25973b656a03abbd89478952 225 Gene3D G3DSA:1.10.1660.10 1 106 6.1E-23 T 11-10-2018 TO73_0629 8162ef4a25973b656a03abbd89478952 225 SUPERFAMILY SSF46955 121 207 8.7E-19 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily TO73_0629 8162ef4a25973b656a03abbd89478952 225 Pfam PF13411 MerR HTH family regulatory protein 121 188 1.8E-18 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TO73_0629 8162ef4a25973b656a03abbd89478952 225 Pfam PF13411 MerR HTH family regulatory protein 2 69 1.8E-18 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TO73_0629 8162ef4a25973b656a03abbd89478952 225 Gene3D G3DSA:1.10.1660.10 114 197 1.3E-22 T 11-10-2018 TO73_0629 8162ef4a25973b656a03abbd89478952 225 SUPERFAMILY SSF46955 2 100 5.49E-20 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily TO73_1970 c3fea06621faac188ffd4affe4501b3d 79 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 26 1.2E-8 T 11-10-2018 IPR025161 Putative transposase IS4/IS5 family TO73_1913 1d5f42b603eebeb51a3bc997c9c3ce8e 368 Gene3D G3DSA:3.30.70.2950 273 359 2.4E-12 T 11-10-2018 TO73_1913 1d5f42b603eebeb51a3bc997c9c3ce8e 368 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 2 358 3.2E-93 T 11-10-2018 IPR019117 CRISPR-associated protein, Cmr3 TO73_0412 dab4912d4841eb3030268e8988be0fca 211 SMART SM00881 76 175 5.1E-14 T 11-10-2018 IPR003781 CoA-binding GO:0048037 TO73_0412 dab4912d4841eb3030268e8988be0fca 211 Gene3D G3DSA:1.10.10.10 1 73 7.0E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0412 dab4912d4841eb3030268e8988be0fca 211 Gene3D G3DSA:3.40.50.720 74 211 5.7E-45 T 11-10-2018 TO73_0412 dab4912d4841eb3030268e8988be0fca 211 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 204 33.757 T 11-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 TO73_0412 dab4912d4841eb3030268e8988be0fca 211 SUPERFAMILY SSF46785 4 76 3.75E-19 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0412 dab4912d4841eb3030268e8988be0fca 211 SUPERFAMILY SSF51735 78 199 5.01E-29 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0412 dab4912d4841eb3030268e8988be0fca 211 Pfam PF06971 Putative DNA-binding protein N-terminus 2 50 4.8E-19 T 11-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 TO73_0412 dab4912d4841eb3030268e8988be0fca 211 Pfam PF02629 CoA binding domain 80 174 4.4E-19 T 11-10-2018 IPR003781 CoA-binding GO:0048037 TO73_0266 bbc21e4a35157325aa918b53f7eef4ec 125 Gene3D G3DSA:2.40.50.140 3 77 3.0E-26 T 11-10-2018 TO73_0266 bbc21e4a35157325aa918b53f7eef4ec 125 Pfam PF00575 S1 RNA binding domain 3 74 8.4E-16 T 11-10-2018 IPR003029 S1 domain GO:0003676 TO73_0266 bbc21e4a35157325aa918b53f7eef4ec 125 SMART SM00316 4 74 3.1E-22 T 11-10-2018 IPR022967 RNA-binding domain, S1 TO73_0266 bbc21e4a35157325aa918b53f7eef4ec 125 SUPERFAMILY SSF50249 4 80 7.92E-22 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 Gene3D G3DSA:3.40.250.10 1 143 4.4E-45 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 SUPERFAMILY SSF52821 160 283 9.43E-40 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 SUPERFAMILY SSF52821 3 143 1.44E-40 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 SMART SM00450 10 124 2.6E-19 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 SMART SM00450 151 278 6.4E-25 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 Gene3D G3DSA:3.40.250.10 144 285 2.3E-49 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 ProSitePatterns PS00380 Rhodanese signature 1. 36 47 - T 11-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 ProSitePatterns PS00683 Rhodanese C-terminal signature. 262 272 - T 11-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 Pfam PF00581 Rhodanese-like domain 12 120 3.2E-15 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_1113 1f6539d7fdd883af075035ac39588c0a 286 Pfam PF00581 Rhodanese-like domain 162 273 1.2E-20 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_0289 41f73e54c7e075daf5b16dd4370b31bd 552 SUPERFAMILY SSF110296 181 416 1.66E-21 T 11-10-2018 TO73_0289 41f73e54c7e075daf5b16dd4370b31bd 552 SUPERFAMILY SSF110296 42 245 1.44E-14 T 11-10-2018 TO73_0289 41f73e54c7e075daf5b16dd4370b31bd 552 SUPERFAMILY SSF110296 359 545 4.71E-14 T 11-10-2018 TO73_0005 28ac60b002fbcb72e2bc9c1063f501b4 142 SUPERFAMILY SSF46626 21 128 4.44E-24 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0005 28ac60b002fbcb72e2bc9c1063f501b4 142 Gene3D G3DSA:1.10.760.10 18 141 3.2E-45 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0005 28ac60b002fbcb72e2bc9c1063f501b4 142 Pfam PF00034 Cytochrome c 20 106 4.0E-11 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1109 03a7f15b4e7a3ae1c62d1f1ab0ea40b4 108 PIRSF PIRSF006639 1 108 2.9E-38 T 11-10-2018 IPR011379 NTP Pyrophosphohydrolase MazG-related, GP37 TO73_1109 03a7f15b4e7a3ae1c62d1f1ab0ea40b4 108 Gene3D G3DSA:1.10.287.1080 1 102 2.9E-18 T 11-10-2018 TO73_1109 03a7f15b4e7a3ae1c62d1f1ab0ea40b4 108 SUPERFAMILY SSF101386 1 96 2.13E-22 T 11-10-2018 TO73_1109 03a7f15b4e7a3ae1c62d1f1ab0ea40b4 108 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 97 2.0E-13 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TO73_0304 873bfe5027232408c23806ea97904e9a 337 Pfam PF02618 YceG-like family 40 329 3.4E-68 T 11-10-2018 IPR003770 Endolytic murein transglycosylase TO73_0304 873bfe5027232408c23806ea97904e9a 337 Gene3D G3DSA:1.10.8.1150 35 104 5.6E-7 T 11-10-2018 TO73_0304 873bfe5027232408c23806ea97904e9a 337 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 35 327 3.0E-53 T 11-10-2018 IPR003770 Endolytic murein transglycosylase TO73_0304 873bfe5027232408c23806ea97904e9a 337 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 14 336 29.199 T 11-10-2018 IPR003770 Endolytic murein transglycosylase TO73_1619 7926c73f7fcba54623d6e73a85162a8f 383 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 69 214 1.3E-38 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TO73_1619 7926c73f7fcba54623d6e73a85162a8f 383 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 68 214 2.1E-38 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TO73_1619 7926c73f7fcba54623d6e73a85162a8f 383 Gene3D G3DSA:1.10.260.150 37 295 4.2E-62 T 11-10-2018 TO73_1336 b801dac3de01719d697146ce500b3ac3 258 Pfam PF06182 ABC-2 family transporter protein 59 257 4.5E-21 T 11-10-2018 IPR010390 Protein of unknown function DUF990 TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 SMART SM00729 132 357 9.7E-52 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 SUPERFAMILY SSF102114 119 363 2.49E-49 T 11-10-2018 TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 3 431 6.2E-170 T 11-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 Pfam PF01938 TRAM domain 371 431 6.1E-5 T 11-10-2018 IPR002792 TRAM domain TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 Pfam PF00919 Uncharacterized protein family UPF0004 3 96 6.1E-19 T 11-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 2 433 60.633 T 11-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 136 156 - T 11-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 Gene3D G3DSA:2.40.50.140 372 434 1.6E-17 T 11-10-2018 TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 431 2.2E-104 T 11-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 Gene3D G3DSA:3.40.50.12160 2 118 6.4E-27 T 11-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 Gene3D G3DSA:3.80.30.20 130 371 1.0E-70 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TO73_1300 02a3d10f01ce97ae726cf09cf1dfbe81 434 Pfam PF04055 Radical SAM superfamily 137 315 6.5E-27 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_0949 c316f74ad51875ee8f0f463d67561d3f 238 Gene3D G3DSA:3.90.550.10 1 203 8.2E-35 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0949 c316f74ad51875ee8f0f463d67561d3f 238 Pfam PF00535 Glycosyl transferase family 2 6 112 1.9E-18 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TO73_0949 c316f74ad51875ee8f0f463d67561d3f 238 SUPERFAMILY SSF53448 1 202 9.21E-43 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 Gene3D G3DSA:3.40.190.10 28 313 1.6E-110 T 11-10-2018 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 Pfam PF13416 Bacterial extracellular solute-binding protein 38 312 1.1E-32 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 SUPERFAMILY SSF53850 24 343 7.48E-86 T 11-10-2018 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 246 265 2.5E-41 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 89 102 2.5E-41 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 29 45 2.5E-41 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 291 317 2.5E-41 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 45 66 2.5E-41 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 73 87 2.5E-41 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 120 136 2.5E-41 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 164 183 2.5E-41 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 PIRSF PIRSF019574 1 345 2.3E-102 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TO73_1435 ac0e65bb0369f494fe1883b03e8432a6 345 Gene3D G3DSA:3.40.190.10 129 341 1.6E-110 T 11-10-2018 TO73_1808 5c950244cb81502be30f7f710b771e40 95 Pfam PF08734 GYD domain 4 91 1.6E-26 T 11-10-2018 IPR014845 Protein GYD/TTHA1554 TO73_2371 f6c90f8b1450a31319478f63a5bf6aaf 405 SUPERFAMILY SSF142338 97 402 4.05E-89 T 11-10-2018 TO73_2371 f6c90f8b1450a31319478f63a5bf6aaf 405 Pfam PF01933 Uncharacterised protein family UPF0052 101 383 8.6E-90 T 11-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 TO73_2371 f6c90f8b1450a31319478f63a5bf6aaf 405 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 101 404 4.8E-99 T 11-10-2018 IPR010119 Gluconeogenesis factor TO73_2371 f6c90f8b1450a31319478f63a5bf6aaf 405 Gene3D G3DSA:3.40.50.12300 96 405 2.4E-110 T 11-10-2018 IPR038136 Gluconeogenesis factor superfamily TO73_2371 f6c90f8b1450a31319478f63a5bf6aaf 405 Hamap MF_00973 Gluconeogenesis factor. 97 405 32.764 T 11-10-2018 IPR010119 Gluconeogenesis factor TO73_0214 fcbb65a6d905e89ca755efb9ef1d379a 88 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 86 5.8E-28 T 11-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0214 fcbb65a6d905e89ca755efb9ef1d379a 88 TIGRFAM TIGR00061 L21: ribosomal protein bL21 1 87 2.2E-24 T 11-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0214 fcbb65a6d905e89ca755efb9ef1d379a 88 SUPERFAMILY SSF141091 1 86 1.31E-26 T 11-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_1231 1741f026780aec5b8fbe68d1d065a998 260 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 260 64.776 T 11-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1231 1741f026780aec5b8fbe68d1d065a998 260 Gene3D G3DSA:3.30.43.10 1 62 3.8E-26 T 11-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TO73_1231 1741f026780aec5b8fbe68d1d065a998 260 SUPERFAMILY SSF56194 168 258 1.83E-26 T 11-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1231 1741f026780aec5b8fbe68d1d065a998 260 SUPERFAMILY SSF56176 3 176 3.31E-29 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TO73_1231 1741f026780aec5b8fbe68d1d065a998 260 Gene3D G3DSA:3.30.465.10 63 183 8.1E-42 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TO73_1231 1741f026780aec5b8fbe68d1d065a998 260 Gene3D G3DSA:3.90.78.10 184 260 4.5E-34 T 11-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1231 1741f026780aec5b8fbe68d1d065a998 260 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 3 251 4.4E-47 T 11-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1231 1741f026780aec5b8fbe68d1d065a998 260 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 168 250 9.4E-22 T 11-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TO73_1231 1741f026780aec5b8fbe68d1d065a998 260 Pfam PF01565 FAD binding domain 28 125 8.0E-9 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TO73_0636 b7d290baac4fa2948ddcf7f6a2ce0e5c 290 SUPERFAMILY SSF109604 67 194 3.68E-8 T 11-10-2018 TO73_0636 b7d290baac4fa2948ddcf7f6a2ce0e5c 290 Gene3D G3DSA:1.10.3210.10 54 205 6.9E-7 T 11-10-2018 TO73_1565 afd40da89a941f4c3ebac590c3ff4216 647 SUPERFAMILY SSF48452 262 420 7.85E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1565 afd40da89a941f4c3ebac590c3ff4216 647 Pfam PF13181 Tetratricopeptide repeat 334 365 0.17 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1565 afd40da89a941f4c3ebac590c3ff4216 647 Pfam PF13432 Tetratricopeptide repeat 276 333 5.0E-7 T 11-10-2018 TO73_1565 afd40da89a941f4c3ebac590c3ff4216 647 SMART SM00028 267 300 21.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1565 afd40da89a941f4c3ebac590c3ff4216 647 SMART SM00028 301 334 0.05 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_1565 afd40da89a941f4c3ebac590c3ff4216 647 SMART SM00028 335 367 24.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0100 66ad5aa4ddc6f2e01fc48fb62d1db596 269 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 1 269 51.346 T 11-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 TO73_0100 66ad5aa4ddc6f2e01fc48fb62d1db596 269 PRINTS PR00474 Glutamate 5-kinase family signature 223 243 1.3E-11 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TO73_0100 66ad5aa4ddc6f2e01fc48fb62d1db596 269 PRINTS PR00474 Glutamate 5-kinase family signature 28 42 1.3E-11 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TO73_0100 66ad5aa4ddc6f2e01fc48fb62d1db596 269 PRINTS PR00474 Glutamate 5-kinase family signature 170 197 1.3E-11 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TO73_0100 66ad5aa4ddc6f2e01fc48fb62d1db596 269 PIRSF PIRSF000728 1 269 1.4E-70 T 11-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_0100 66ad5aa4ddc6f2e01fc48fb62d1db596 269 TIGRFAM TIGR00761 argB: acetylglutamate kinase 1 247 3.6E-75 T 11-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_0100 66ad5aa4ddc6f2e01fc48fb62d1db596 269 Gene3D G3DSA:3.40.1160.10 1 269 1.6E-74 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_0100 66ad5aa4ddc6f2e01fc48fb62d1db596 269 SUPERFAMILY SSF53633 1 268 1.57E-52 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_0100 66ad5aa4ddc6f2e01fc48fb62d1db596 269 Pfam PF00696 Amino acid kinase family 1 248 1.7E-37 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 443 3.7E-166 T 11-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 Gene3D G3DSA:3.10.20.70 2 109 2.8E-37 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 2.7E-27 T 11-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 SMART SM01230 107 356 9.9E-138 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 Gene3D G3DSA:3.30.590.10 110 446 1.3E-139 T 11-10-2018 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 236 251 - T 11-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 SUPERFAMILY SSF54368 4 106 2.62E-29 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 SUPERFAMILY SSF55931 107 443 8.93E-130 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 11-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TO73_0604 8ef5fbc9e4431a9e4c7ee11cd667a1e4 446 Pfam PF00120 Glutamine synthetase, catalytic domain 108 442 2.7E-139 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TO73_1816 ab7f99f64cfd123a6225886b90a1fe0e 550 SUPERFAMILY SSF52096 22 269 1.01E-65 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_1816 ab7f99f64cfd123a6225886b90a1fe0e 550 Gene3D G3DSA:3.90.226.10 274 545 2.9E-91 T 11-10-2018 TO73_1816 ab7f99f64cfd123a6225886b90a1fe0e 550 Pfam PF01039 Carboxyl transferase domain 45 540 1.4E-139 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TO73_1816 ab7f99f64cfd123a6225886b90a1fe0e 550 SUPERFAMILY SSF52096 277 543 1.22E-79 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_1816 ab7f99f64cfd123a6225886b90a1fe0e 550 Gene3D G3DSA:3.90.226.10 1 266 5.7E-86 T 11-10-2018 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 PIRSF PIRSF001415 1 326 4.1E-140 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 Gene3D G3DSA:3.20.20.70 1 326 4.3E-139 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 SUPERFAMILY SSF51569 3 325 2.64E-129 T 11-10-2018 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 117 131 7.2E-58 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 7.2E-58 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 7.2E-58 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 7.2E-58 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 7.2E-58 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 7.2E-58 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 Pfam PF00490 Delta-aminolevulinic acid dehydratase 2 322 2.8E-135 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 11-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_0493 3e80c6435eb3a1657c5141266e95eabb 326 SMART SM01004 1 323 4.2E-213 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TO73_1705 11c0c6ab6e7f6ecb1534d693c1842bf7 247 Pfam PF01925 Sulfite exporter TauE/SafE 5 242 1.2E-48 T 11-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 Gene3D G3DSA:3.20.20.70 17 308 5.6E-104 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 149 180 - T 11-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 21 301 2.0E-85 T 11-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 TIGRFAM TIGR02313 HpaI-NOT-DapA: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 18 308 1.3E-161 T 11-10-2018 IPR012691 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase variant GO:0005737|GO:0008840|GO:0019877 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 50 71 1.5E-27 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 86 104 1.5E-27 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 118 134 1.5E-27 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 144 161 1.5E-27 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 PIRSF PIRSF001365 13 311 1.5E-86 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 SUPERFAMILY SSF51569 15 308 1.0E-94 T 11-10-2018 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 Pfam PF00701 Dihydrodipicolinate synthetase family 18 302 7.9E-83 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 SMART SM01130 17 306 1.4E-123 T 11-10-2018 IPR002220 DapA-like GO:0016829 TO73_1005 7fd7bb86af67c88ad96403621215f0b9 312 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 17 304 57.292 T 11-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TO73_1575 a552089bb1d28d7e25fc85a24c7f93de 272 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 51 78 - T 11-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TO73_1575 a552089bb1d28d7e25fc85a24c7f93de 272 Gene3D G3DSA:3.40.50.150 3 203 3.2E-65 T 11-10-2018 TO73_1575 a552089bb1d28d7e25fc85a24c7f93de 272 SMART SM00650 36 202 2.1E-62 T 11-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TO73_1575 a552089bb1d28d7e25fc85a24c7f93de 272 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 20 268 47.89 T 11-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TO73_1575 a552089bb1d28d7e25fc85a24c7f93de 272 Pfam PF00398 Ribosomal RNA adenine dimethylase 24 255 1.4E-40 T 11-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TO73_1575 a552089bb1d28d7e25fc85a24c7f93de 272 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 22 266 8.3E-67 T 11-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TO73_1575 a552089bb1d28d7e25fc85a24c7f93de 272 Gene3D G3DSA:1.10.8.100 205 270 8.9E-25 T 11-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 TO73_1575 a552089bb1d28d7e25fc85a24c7f93de 272 SUPERFAMILY SSF53335 17 268 1.72E-57 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2052 a8094bc40848dd0254dec4a06ceef5fe 313 Gene3D G3DSA:3.30.70.20 21 77 2.9E-10 T 11-10-2018 TO73_2052 a8094bc40848dd0254dec4a06ceef5fe 313 Pfam PF12798 4Fe-4S binding domain 35 47 0.13 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_2052 a8094bc40848dd0254dec4a06ceef5fe 313 SUPERFAMILY SSF54862 231 297 4.13E-15 T 11-10-2018 TO73_2052 a8094bc40848dd0254dec4a06ceef5fe 313 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_2052 a8094bc40848dd0254dec4a06ceef5fe 313 Gene3D G3DSA:3.30.70.20 233 306 2.2E-12 T 11-10-2018 TO73_2052 a8094bc40848dd0254dec4a06ceef5fe 313 SUPERFAMILY SSF54862 9 77 2.26E-14 T 11-10-2018 TO73_2052 a8094bc40848dd0254dec4a06ceef5fe 313 Pfam PF13237 4Fe-4S dicluster domain 236 283 8.8E-9 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_2052 a8094bc40848dd0254dec4a06ceef5fe 313 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 272 283 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_2052 a8094bc40848dd0254dec4a06ceef5fe 313 Pfam PF00037 4Fe-4S binding domain 56 77 4.8E-5 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_1983 f54b9c6164289fafb037a3854d2f2d73 158 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 1.1E-51 T 11-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TO73_1983 f54b9c6164289fafb037a3854d2f2d73 158 Pfam PF03477 ATP cone domain 50 132 2.0E-14 T 11-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TO73_1983 f54b9c6164289fafb037a3854d2f2d73 158 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 77.394 T 11-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TO73_1748 939ccf520eabdad7eecaca36abfbbbc4 273 Pfam PF01842 ACT domain 190 250 6.7E-8 T 11-10-2018 IPR002912 ACT domain TO73_1748 939ccf520eabdad7eecaca36abfbbbc4 273 Gene3D G3DSA:3.40.190.10 85 165 1.0E-29 T 11-10-2018 TO73_1748 939ccf520eabdad7eecaca36abfbbbc4 273 SUPERFAMILY SSF53850 1 181 1.76E-63 T 11-10-2018 TO73_1748 939ccf520eabdad7eecaca36abfbbbc4 273 SUPERFAMILY SSF55021 172 268 4.93E-25 T 11-10-2018 TO73_1748 939ccf520eabdad7eecaca36abfbbbc4 273 Gene3D G3DSA:3.40.190.10 1 84 6.0E-30 T 11-10-2018 TO73_1748 939ccf520eabdad7eecaca36abfbbbc4 273 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 216 223 - T 11-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TO73_1748 939ccf520eabdad7eecaca36abfbbbc4 273 Gene3D G3DSA:3.30.70.260 183 270 3.3E-29 T 11-10-2018 TO73_1748 939ccf520eabdad7eecaca36abfbbbc4 273 Pfam PF00800 Prephenate dehydratase 3 179 3.6E-63 T 11-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 SUPERFAMILY SSF52317 161 369 1.57E-54 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 Pfam PF00117 Glutamine amidotransferase class-I 191 364 2.1E-41 T 11-10-2018 IPR017926 Glutamine amidotransferase TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 Gene3D G3DSA:3.50.30.20 2 152 2.3E-56 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 228 242 1.1E-36 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 275 292 1.1E-36 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 189 203 1.1E-36 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 274 1.1E-36 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 300 311 1.1E-36 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 371 47.645 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 4.2E-51 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00096 Glutamine amidotransferase superfamily signature 342 355 3.0E-12 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 240 3.0E-12 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00096 Glutamine amidotransferase superfamily signature 258 269 3.0E-12 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00097 Anthranilate synthase component II signature 258 269 4.3E-7 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00097 Anthranilate synthase component II signature 231 240 4.3E-7 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 PRINTS PR00097 Anthranilate synthase component II signature 342 355 4.3E-7 T 11-10-2018 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 Gene3D G3DSA:3.40.50.880 162 371 5.5E-63 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 368 1.3E-145 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 SMART SM01097 3 133 2.1E-87 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_0164 2669bb25a783d4a3a6de8bf1fd121cd4 388 SUPERFAMILY SSF52021 4 138 3.92E-55 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_2295 49988e7c2ed6af88e501dfd078cce299 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 251 5.1E-18 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_2295 49988e7c2ed6af88e501dfd078cce299 261 Gene3D G3DSA:1.10.3720.10 1 252 7.9E-49 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2295 49988e7c2ed6af88e501dfd078cce299 261 SUPERFAMILY SSF161098 2 253 2.09E-47 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2133 be46d6ae8c24bf5674cf8e3afa063ce4 300 Pfam PF00294 pfkB family carbohydrate kinase 2 286 6.7E-33 T 11-10-2018 IPR011611 Carbohydrate kinase PfkB TO73_2133 be46d6ae8c24bf5674cf8e3afa063ce4 300 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 229 242 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TO73_2133 be46d6ae8c24bf5674cf8e3afa063ce4 300 SUPERFAMILY SSF53613 4 285 7.64E-49 T 11-10-2018 IPR029056 Ribokinase-like TO73_2133 be46d6ae8c24bf5674cf8e3afa063ce4 300 Gene3D G3DSA:3.40.1190.20 1 289 2.4E-57 T 11-10-2018 IPR029056 Ribokinase-like TO73_1027 a6d6524b10a33907051cbf0cc3a32693 570 Gene3D G3DSA:1.10.569.10 241 419 5.0E-55 T 11-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TO73_1027 a6d6524b10a33907051cbf0cc3a32693 570 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 203 4.9E-47 T 11-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_1027 a6d6524b10a33907051cbf0cc3a32693 570 SUPERFAMILY SSF48310 210 565 1.2E-77 T 11-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_1027 a6d6524b10a33907051cbf0cc3a32693 570 SUPERFAMILY SSF56228 3 204 2.88E-46 T 11-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TO73_1027 a6d6524b10a33907051cbf0cc3a32693 570 Gene3D G3DSA:3.60.9.10 2 210 8.2E-49 T 11-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TO73_1027 a6d6524b10a33907051cbf0cc3a32693 570 Gene3D G3DSA:1.10.599.10 240 549 5.0E-55 T 11-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TO73_1027 a6d6524b10a33907051cbf0cc3a32693 570 SMART SM00790 2 207 1.6E-72 T 11-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_1027 a6d6524b10a33907051cbf0cc3a32693 570 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 219 552 9.8E-59 T 11-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TO73_0683 c8997c85183bc627e8b645db1c94684b 324 Gene3D G3DSA:3.30.565.10 185 324 2.1E-21 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_0683 c8997c85183bc627e8b645db1c94684b 324 SUPERFAMILY SSF47384 99 182 3.34E-13 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TO73_0683 c8997c85183bc627e8b645db1c94684b 324 SMART SM00304 57 115 0.0028 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TO73_0683 c8997c85183bc627e8b645db1c94684b 324 PRINTS PR00344 Bacterial sensor protein C-terminal signature 255 269 1.3E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0683 c8997c85183bc627e8b645db1c94684b 324 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 322 1.3E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0683 c8997c85183bc627e8b645db1c94684b 324 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 303 1.3E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TO73_0683 c8997c85183bc627e8b645db1c94684b 324 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 224 322 8.3E-11 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_0683 c8997c85183bc627e8b645db1c94684b 324 SMART SM00388 116 183 5.1E-7 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_0683 c8997c85183bc627e8b645db1c94684b 324 SMART SM00387 224 324 4.2E-17 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TO73_0683 c8997c85183bc627e8b645db1c94684b 324 SUPERFAMILY SSF55874 188 323 2.62E-23 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TO73_0683 c8997c85183bc627e8b645db1c94684b 324 Pfam PF00512 His Kinase A (phospho-acceptor) domain 117 182 3.0E-7 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TO73_0683 c8997c85183bc627e8b645db1c94684b 324 Gene3D G3DSA:1.10.287.130 61 184 1.9E-14 T 11-10-2018 TO73_1478 8f3f6f18ca1135671e5282870a46e2c0 406 Gene3D G3DSA:1.20.81.30 255 367 6.0E-30 T 11-10-2018 TO73_1478 8f3f6f18ca1135671e5282870a46e2c0 406 Gene3D G3DSA:1.20.81.30 53 168 5.6E-35 T 11-10-2018 TO73_1478 8f3f6f18ca1135671e5282870a46e2c0 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 368 382 5.2E-19 T 11-10-2018 IPR003004 GspF/PilC family TO73_1478 8f3f6f18ca1135671e5282870a46e2c0 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 403 5.2E-19 T 11-10-2018 IPR003004 GspF/PilC family TO73_1478 8f3f6f18ca1135671e5282870a46e2c0 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 66 78 5.2E-19 T 11-10-2018 IPR003004 GspF/PilC family TO73_1478 8f3f6f18ca1135671e5282870a46e2c0 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 5.2E-19 T 11-10-2018 IPR003004 GspF/PilC family TO73_1478 8f3f6f18ca1135671e5282870a46e2c0 406 Pfam PF00482 Type II secretion system (T2SS), protein F 272 395 4.7E-31 T 11-10-2018 IPR018076 Type II secretion system F domain TO73_1478 8f3f6f18ca1135671e5282870a46e2c0 406 Pfam PF00482 Type II secretion system (T2SS), protein F 70 192 2.5E-31 T 11-10-2018 IPR018076 Type II secretion system F domain TO73_1478 8f3f6f18ca1135671e5282870a46e2c0 406 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 164 192 - T 11-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 TO73_0542 4dad2e20177b3f2a6e710e8fd0c52ed2 244 Gene3D G3DSA:3.30.1600.10 31 166 2.6E-82 T 11-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily TO73_0542 4dad2e20177b3f2a6e710e8fd0c52ed2 244 Gene3D G3DSA:3.40.50.1220 13 237 2.6E-82 T 11-10-2018 TO73_0542 4dad2e20177b3f2a6e710e8fd0c52ed2 244 SUPERFAMILY SSF52467 3 241 3.64E-83 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TO73_0542 4dad2e20177b3f2a6e710e8fd0c52ed2 244 Pfam PF02146 Sir2 family 22 196 6.6E-48 T 11-10-2018 IPR003000 Sirtuin family GO:0070403 TO73_0542 4dad2e20177b3f2a6e710e8fd0c52ed2 244 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 15 243 60.623 T 11-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 TO73_2357 d138d8a5265fa763fe2a9ba893e657f2 413 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 2 412 39.368 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TO73_2357 d138d8a5265fa763fe2a9ba893e657f2 413 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 402 2.0E-132 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TO73_2357 d138d8a5265fa763fe2a9ba893e657f2 413 PIRSF PIRSF000151 2 413 8.2E-158 T 11-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 TO73_2357 d138d8a5265fa763fe2a9ba893e657f2 413 Gene3D G3DSA:3.40.309.10 222 370 9.4E-154 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TO73_2357 d138d8a5265fa763fe2a9ba893e657f2 413 Pfam PF00171 Aldehyde dehydrogenase family 39 279 4.0E-17 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TO73_2357 d138d8a5265fa763fe2a9ba893e657f2 413 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 319 340 - T 11-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TO73_2357 d138d8a5265fa763fe2a9ba893e657f2 413 SUPERFAMILY SSF53720 7 412 1.57E-109 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TO73_2357 d138d8a5265fa763fe2a9ba893e657f2 413 Gene3D G3DSA:3.40.605.10 15 407 9.4E-154 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TO73_0494 af4fbc043bf27d38998d7a13b180790a 397 SUPERFAMILY SSF103473 5 387 2.09E-46 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_0494 af4fbc043bf27d38998d7a13b180790a 397 Gene3D G3DSA:1.20.1250.20 2 385 6.3E-37 T 11-10-2018 TO73_0494 af4fbc043bf27d38998d7a13b180790a 397 Pfam PF05977 Transmembrane secretion effector 4 384 8.8E-33 T 11-10-2018 IPR010290 Transmembrane secretion effector TO73_2385 a3dbf2aa6563641490925e70ed9423aa 209 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 70 206 1.7E-8 T 11-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TO73_2385 a3dbf2aa6563641490925e70ed9423aa 209 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 54 6.0E-17 T 11-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TO73_2385 a3dbf2aa6563641490925e70ed9423aa 209 Gene3D G3DSA:3.20.20.190 1 209 7.6E-58 T 11-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TO73_2385 a3dbf2aa6563641490925e70ed9423aa 209 SUPERFAMILY SSF51695 2 208 6.91E-53 T 11-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TO73_1875 232b642da3ef6824463644a306102bd2 343 Pfam PF01380 SIS domain 45 163 2.5E-12 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TO73_1875 232b642da3ef6824463644a306102bd2 343 Pfam PF01380 SIS domain 197 285 1.1E-14 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TO73_1875 232b642da3ef6824463644a306102bd2 343 SUPERFAMILY SSF53697 4 341 7.3E-68 T 11-10-2018 TO73_1875 232b642da3ef6824463644a306102bd2 343 Gene3D G3DSA:3.40.50.10490 191 342 3.4E-39 T 11-10-2018 TO73_1875 232b642da3ef6824463644a306102bd2 343 Gene3D G3DSA:3.40.50.10490 1 190 5.2E-46 T 11-10-2018 TO73_2303 61981e24b75c64999381c028b9ec2711 910 Gene3D G3DSA:1.20.5.340 150 248 6.3E-6 T 11-10-2018 TO73_2303 61981e24b75c64999381c028b9ec2711 910 Pfam PF00395 S-layer homology domain 25 67 1.8E-12 T 11-10-2018 IPR001119 S-layer homology domain TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 4.1E-56 T 11-10-2018 TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 5.2E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 5.2E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 5.2E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 7 250 1.2E-96 T 11-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 SUPERFAMILY SSF51735 6 250 3.57E-75 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.1E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.1E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.1E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.1E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.1E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.1E-40 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0938 d1fd7480a8d7fd3f8b2cc0152a9d5b89 251 Gene3D G3DSA:3.40.50.720 1 251 4.6E-79 T 11-10-2018 TO73_0394 aff52557638f419b24f1dd9cd7cefdf9 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 17.623 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0394 aff52557638f419b24f1dd9cd7cefdf9 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 53 1.9E-15 T 11-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TO73_0394 aff52557638f419b24f1dd9cd7cefdf9 60 Gene3D G3DSA:3.30.1390.20 1 60 3.4E-24 T 11-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TO73_0394 aff52557638f419b24f1dd9cd7cefdf9 60 SUPERFAMILY SSF55129 1 59 1.7E-17 T 11-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TO73_0394 aff52557638f419b24f1dd9cd7cefdf9 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 57 1.1E-24 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0394 aff52557638f419b24f1dd9cd7cefdf9 60 PIRSF PIRSF002211 1 60 1.5E-24 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_2210 3652d313317e3a54a88b30292f569f2c 401 SUPERFAMILY SSF161098 178 384 5.63E-37 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2210 3652d313317e3a54a88b30292f569f2c 401 Gene3D G3DSA:1.10.3720.10 178 400 4.2E-33 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2210 3652d313317e3a54a88b30292f569f2c 401 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 162 398 4.6E-68 T 11-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 TO73_2210 3652d313317e3a54a88b30292f569f2c 401 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 202 390 1.4E-23 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_2156 42a5a111213bfaa6693df4c0af8e9006 55 Pfam PF01965 DJ-1/PfpI family 14 53 8.6E-8 T 11-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TO73_2156 42a5a111213bfaa6693df4c0af8e9006 55 SUPERFAMILY SSF52317 13 55 5.04E-10 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_2156 42a5a111213bfaa6693df4c0af8e9006 55 Gene3D G3DSA:3.40.50.880 5 55 6.4E-9 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_2410 15f7725fd3c9c5a476377688e8078955 168 SMART SM00987 1 143 1.0E-29 T 11-10-2018 TO73_2410 15f7725fd3c9c5a476377688e8078955 168 SMART SM00986 1 143 1.0E-29 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TO73_2410 15f7725fd3c9c5a476377688e8078955 168 Pfam PF03167 Uracil DNA glycosylase superfamily 1 127 9.4E-45 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TO73_2410 15f7725fd3c9c5a476377688e8078955 168 SUPERFAMILY SSF52141 1 150 2.98E-56 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TO73_2410 15f7725fd3c9c5a476377688e8078955 168 Gene3D G3DSA:3.40.470.10 1 168 1.6E-67 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TO73_2410 15f7725fd3c9c5a476377688e8078955 168 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 1 132 1.4E-50 T 11-10-2018 IPR005273 Uracil-DNA glycosylase family 4 TO73_0871 85780105d8df81749bf98be684b941ab 440 Gene3D G3DSA:3.40.50.880 251 428 3.7E-5 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0871 85780105d8df81749bf98be684b941ab 440 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 433 1.0E-114 T 11-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 TO73_0871 85780105d8df81749bf98be684b941ab 440 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 3 424 39.814 T 11-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 TO73_0871 85780105d8df81749bf98be684b941ab 440 SUPERFAMILY SSF52317 241 432 7.64E-30 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0871 85780105d8df81749bf98be684b941ab 440 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 243 420 1.3E-28 T 11-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TO73_0871 85780105d8df81749bf98be684b941ab 440 Gene3D G3DSA:3.40.50.300 5 189 1.0E-25 T 11-10-2018 TO73_0871 85780105d8df81749bf98be684b941ab 440 SUPERFAMILY SSF52540 5 198 2.25E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0871 85780105d8df81749bf98be684b941ab 440 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 191 2.0E-15 T 11-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TO73_0532 af77788a0825e991e9fe0427a927ac32 184 SUPERFAMILY SSF50022 58 175 2.47E-18 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TO73_0532 af77788a0825e991e9fe0427a927ac32 184 Gene3D G3DSA:2.102.10.10 44 178 4.6E-23 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TO73_0532 af77788a0825e991e9fe0427a927ac32 184 Pfam PF00355 Rieske [2Fe-2S] domain 92 158 1.3E-7 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TO73_1104 dc3fea0becfba9108c5c3abaa1f6fa38 111 SUPERFAMILY SSF56317 7 109 2.22E-12 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TO73_1104 dc3fea0becfba9108c5c3abaa1f6fa38 111 Gene3D G3DSA:3.60.110.10 2 111 2.9E-14 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TO73_0705 90cc611e8effdfe034b58649b501ccb0 115 Gene3D G3DSA:1.10.3830.10 1 108 1.8E-34 T 11-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 TO73_0705 90cc611e8effdfe034b58649b501ccb0 115 Pfam PF01219 Prokaryotic diacylglycerol kinase 7 104 2.9E-31 T 11-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 TO73_1009 d51556e99a6fbf539ee7ccce177cc558 367 Pfam PF01903 CbiX 127 195 7.1E-6 T 11-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 TO73_1009 d51556e99a6fbf539ee7ccce177cc558 367 Pfam PF01903 CbiX 7 108 2.3E-17 T 11-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 TO73_1009 d51556e99a6fbf539ee7ccce177cc558 367 SUPERFAMILY SSF52833 279 363 2.24E-17 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1009 d51556e99a6fbf539ee7ccce177cc558 367 SUPERFAMILY SSF53800 2 230 5.89E-31 T 11-10-2018 TO73_1009 d51556e99a6fbf539ee7ccce177cc558 367 Gene3D G3DSA:3.40.50.1400 1 115 7.9E-23 T 11-10-2018 TO73_1009 d51556e99a6fbf539ee7ccce177cc558 367 Gene3D G3DSA:3.40.50.1400 116 232 2.5E-15 T 11-10-2018 TO73_1009 d51556e99a6fbf539ee7ccce177cc558 367 Gene3D G3DSA:3.40.30.10 276 366 4.7E-18 T 11-10-2018 TO73_0633 1e79150b322c440c91bb2a034a23bf80 208 Pfam PF00005 ABC transporter 20 165 2.0E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0633 1e79150b322c440c91bb2a034a23bf80 208 SUPERFAMILY SSF52540 5 201 2.61E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0633 1e79150b322c440c91bb2a034a23bf80 208 SMART SM00382 28 207 2.3E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0633 1e79150b322c440c91bb2a034a23bf80 208 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0633 1e79150b322c440c91bb2a034a23bf80 208 Gene3D G3DSA:3.40.50.300 2 205 1.3E-55 T 11-10-2018 TO73_0597 7a6b8a4a0ee7c404cb99bd6895097387 306 SUPERFAMILY SSF161098 92 290 3.92E-21 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0597 7a6b8a4a0ee7c404cb99bd6895097387 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 305 5.5E-42 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0597 7a6b8a4a0ee7c404cb99bd6895097387 306 Gene3D G3DSA:1.10.3720.10 89 300 4.3E-27 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1960 9d60fe25189278358fbd9282a023caec 76 Gene3D G3DSA:1.10.10.10 2 63 1.2E-5 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1960 9d60fe25189278358fbd9282a023caec 76 SUPERFAMILY SSF46785 3 60 1.61E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_2830 de2ae2ebb8713b622e4138654adbb66f 210 Pfam PF11866 Protein of unknown function (DUF3386) 9 193 1.3E-18 T 11-10-2018 IPR021809 Protein of unknown function DUF3386 TO73_0845 1b4850d3b78dc706b5350ac45fa1935d 368 Pfam PF00487 Fatty acid desaturase 72 312 1.3E-38 T 11-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 TO73_2065 4f7ad7b5fb0953249c4f181946d85290 109 Pfam PF01909 Nucleotidyltransferase domain 26 65 1.5E-10 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TO73_2065 4f7ad7b5fb0953249c4f181946d85290 109 Gene3D G3DSA:3.30.460.10 6 104 1.1E-14 T 11-10-2018 TO73_2065 4f7ad7b5fb0953249c4f181946d85290 109 SUPERFAMILY SSF81301 13 87 5.45E-15 T 11-10-2018 TO73_2137 3263d35756cbd09880d6a0ecbb7e4a63 96 Pfam PF13601 Winged helix DNA-binding domain 12 92 5.6E-26 T 11-10-2018 IPR027395 Winged helix DNA-binding domain TO73_2137 3263d35756cbd09880d6a0ecbb7e4a63 96 Gene3D G3DSA:1.10.10.10 1 95 4.3E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2137 3263d35756cbd09880d6a0ecbb7e4a63 96 SUPERFAMILY SSF46785 7 92 6.84E-16 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0265 70fd6318b4265bbee3c209748589142f 159 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 4 130 6.4E-37 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TO73_0265 70fd6318b4265bbee3c209748589142f 159 Gene3D G3DSA:3.30.70.560 1 156 1.1E-55 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TO73_0265 70fd6318b4265bbee3c209748589142f 159 SUPERFAMILY SSF55083 2 154 2.49E-54 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TO73_0265 70fd6318b4265bbee3c209748589142f 159 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 86 97 - T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TO73_0265 70fd6318b4265bbee3c209748589142f 159 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 3 131 2.4E-44 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TO73_1131 5efd298f751a7ed9bf6b92f99f44c76c 248 SUPERFAMILY SSF56752 19 233 1.57E-43 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TO73_1131 5efd298f751a7ed9bf6b92f99f44c76c 248 Gene3D G3DSA:3.20.10.10 103 248 6.2E-35 T 11-10-2018 TO73_1131 5efd298f751a7ed9bf6b92f99f44c76c 248 Pfam PF01063 Amino-transferase class IV 26 227 2.9E-34 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TO73_1131 5efd298f751a7ed9bf6b92f99f44c76c 248 Gene3D G3DSA:3.30.470.10 5 102 1.6E-20 T 11-10-2018 TO73_0036 bbf6047f8468ff342767a6a73b34f3e5 291 Gene3D G3DSA:1.10.3720.10 49 289 6.3E-72 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0036 bbf6047f8468ff342767a6a73b34f3e5 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 281 9.2E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0036 bbf6047f8468ff342767a6a73b34f3e5 291 SUPERFAMILY SSF161098 53 280 1.7E-62 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1874 9030cc2930c146a7edcd1dca111fe95f 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 5 109 2.0E-46 T 11-10-2018 IPR008231 Probable chaperone CsaA TO73_1874 9030cc2930c146a7edcd1dca111fe95f 109 Gene3D G3DSA:2.40.50.140 3 109 4.5E-30 T 11-10-2018 TO73_1874 9030cc2930c146a7edcd1dca111fe95f 109 SUPERFAMILY SSF50249 5 108 2.45E-31 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1874 9030cc2930c146a7edcd1dca111fe95f 109 Pfam PF01588 Putative tRNA binding domain 12 107 5.0E-16 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TO73_2041 1884e0a0e7d40db10cbbad571c6ede8a 130 Pfam PF02036 SCP-2 sterol transfer family 11 106 1.9E-10 T 11-10-2018 IPR003033 SCP2 sterol-binding domain TO73_2041 1884e0a0e7d40db10cbbad571c6ede8a 130 SUPERFAMILY SSF55718 2 129 2.83E-31 T 11-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TO73_2041 1884e0a0e7d40db10cbbad571c6ede8a 130 Gene3D G3DSA:3.30.1050.10 1 130 1.5E-39 T 11-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TO73_1548 cb38acc955adf0813c6d8507fde000d8 268 SUPERFAMILY SSF81345 4 261 4.71E-27 T 11-10-2018 IPR037294 ABC transporter, BtuC-like TO73_1548 cb38acc955adf0813c6d8507fde000d8 268 Pfam PF00950 ABC 3 transport family 6 260 1.6E-60 T 11-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TO73_0315 22014a3e3b2e9b95317ffaa52650c493 257 Gene3D G3DSA:3.30.70.1400 19 99 6.9E-10 T 11-10-2018 TO73_0315 22014a3e3b2e9b95317ffaa52650c493 257 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 132 185 1.0E-11 T 11-10-2018 IPR017703 YgfZ/GcvT conserved site TO73_0315 22014a3e3b2e9b95317ffaa52650c493 257 SUPERFAMILY SSF103025 19 173 1.05E-21 T 11-10-2018 TO73_0315 22014a3e3b2e9b95317ffaa52650c493 257 Gene3D G3DSA:3.30.1360.120 115 245 1.7E-11 T 11-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 ProSitePatterns PS01135 FtsZ protein signature 2. 89 110 - T 11-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 SMART SM00865 199 317 1.2E-36 T 11-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 SMART SM00864 5 197 1.2E-110 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 1 341 37.074 T 11-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 Gene3D G3DSA:3.40.50.1440 3 309 2.4E-111 T 11-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 3 312 9.6E-118 T 11-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 PRINTS PR00423 Cell division protein FtsZ signature 204 225 1.1E-46 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 PRINTS PR00423 Cell division protein FtsZ signature 118 139 1.1E-46 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 PRINTS PR00423 Cell division protein FtsZ signature 181 203 1.1E-46 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 PRINTS PR00423 Cell division protein FtsZ signature 90 110 1.1E-46 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 ProSitePatterns PS01134 FtsZ protein signature 1. 36 70 - T 11-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 6 164 2.4E-41 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 SUPERFAMILY SSF52490 5 200 4.32E-68 T 11-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 Pfam PF12327 FtsZ family, C-terminal domain 214 308 2.5E-22 T 11-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TO73_1234 a5f1d6c84688281998b7e3ecfaa91b56 351 SUPERFAMILY SSF55307 196 313 7.55E-34 T 11-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TO73_2281 cc6651ad4e51b1a3c87a4f304b705dac 171 Pfam PF03641 Possible lysine decarboxylase 45 160 1.2E-9 T 11-10-2018 IPR031100 LOG family TO73_2281 cc6651ad4e51b1a3c87a4f304b705dac 171 Gene3D G3DSA:3.40.50.450 1 171 1.1E-52 T 11-10-2018 TO73_2281 cc6651ad4e51b1a3c87a4f304b705dac 171 SUPERFAMILY SSF102405 1 169 1.11E-30 T 11-10-2018 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 SMART SM00098 39 471 7.2E-42 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 Pfam PF00245 Alkaline phosphatase 39 469 1.3E-66 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 Gene3D G3DSA:1.10.1200.140 359 442 1.2E-95 T 11-10-2018 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 SUPERFAMILY SSF53649 34 474 3.11E-99 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 PRINTS PR00113 Alkaline phosphatase signature 129 149 9.9E-33 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 PRINTS PR00113 Alkaline phosphatase signature 38 58 9.9E-33 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 PRINTS PR00113 Alkaline phosphatase signature 246 275 9.9E-33 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 PRINTS PR00113 Alkaline phosphatase signature 173 183 9.9E-33 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 PRINTS PR00113 Alkaline phosphatase signature 92 107 9.9E-33 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TO73_0950 7d5c9e44a22bc3947b88fd1b9a4172c4 501 Gene3D G3DSA:3.40.720.10 39 444 1.2E-95 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 Hamap MF_00186 Glycerol kinase [glpK]. 1 492 55.407 T 11-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 490 4.1E-206 T 11-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 249 2.7E-73 T 11-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 446 4.8E-59 T 11-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 PIRSF PIRSF000538 1 495 3.1E-171 T 11-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 Gene3D G3DSA:3.30.420.40 251 495 1.1E-86 T 11-10-2018 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 SUPERFAMILY SSF53067 1 250 1.73E-91 T 11-10-2018 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 358 378 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 Gene3D G3DSA:3.30.420.40 1 250 2.0E-108 T 11-10-2018 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 SUPERFAMILY SSF53067 255 489 8.33E-75 T 11-10-2018 TO73_1797 de2f00936afec66fd8fbd006164f43dd 495 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 133 145 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TO73_1132 12b272671b601edbfe89a1c82854322c 616 PRINTS PR00096 Glutamine amidotransferase superfamily signature 592 605 5.4E-11 T 11-10-2018 TO73_1132 12b272671b601edbfe89a1c82854322c 616 PRINTS PR00096 Glutamine amidotransferase superfamily signature 478 487 5.4E-11 T 11-10-2018 TO73_1132 12b272671b601edbfe89a1c82854322c 616 PRINTS PR00096 Glutamine amidotransferase superfamily signature 506 517 5.4E-11 T 11-10-2018 TO73_1132 12b272671b601edbfe89a1c82854322c 616 PRINTS PR00097 Anthranilate synthase component II signature 592 605 4.8E-25 T 11-10-2018 TO73_1132 12b272671b601edbfe89a1c82854322c 616 PRINTS PR00097 Anthranilate synthase component II signature 506 517 4.8E-25 T 11-10-2018 TO73_1132 12b272671b601edbfe89a1c82854322c 616 PRINTS PR00097 Anthranilate synthase component II signature 530 538 4.8E-25 T 11-10-2018 TO73_1132 12b272671b601edbfe89a1c82854322c 616 PRINTS PR00097 Anthranilate synthase component II signature 478 487 4.8E-25 T 11-10-2018 TO73_1132 12b272671b601edbfe89a1c82854322c 616 PRINTS PR00097 Anthranilate synthase component II signature 437 451 4.8E-25 T 11-10-2018 TO73_1132 12b272671b601edbfe89a1c82854322c 616 PRINTS PR00097 Anthranilate synthase component II signature 550 562 4.8E-25 T 11-10-2018 TO73_1132 12b272671b601edbfe89a1c82854322c 616 Pfam PF04715 Anthranilate synthase component I, N terminal region 4 112 2.1E-4 T 11-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TO73_1132 12b272671b601edbfe89a1c82854322c 616 SUPERFAMILY SSF56322 16 406 2.22E-116 T 11-10-2018 IPR005801 ADC synthase GO:0009058 TO73_1132 12b272671b601edbfe89a1c82854322c 616 Gene3D G3DSA:3.40.50.880 435 615 1.9E-54 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1132 12b272671b601edbfe89a1c82854322c 616 Pfam PF00425 chorismate binding enzyme 149 398 1.0E-90 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TO73_1132 12b272671b601edbfe89a1c82854322c 616 Gene3D G3DSA:3.60.120.10 5 408 4.0E-121 T 11-10-2018 IPR005801 ADC synthase GO:0009058 TO73_1132 12b272671b601edbfe89a1c82854322c 616 Pfam PF00117 Glutamine amidotransferase class-I 440 613 5.1E-39 T 11-10-2018 IPR017926 Glutamine amidotransferase TO73_1132 12b272671b601edbfe89a1c82854322c 616 SUPERFAMILY SSF52317 436 614 6.73E-45 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1132 12b272671b601edbfe89a1c82854322c 616 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 437 614 3.6E-37 T 11-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TO73_1168 0aca2dec42a6e406b2fee7455503d241 381 SUPERFAMILY SSF56436 76 378 5.27E-14 T 11-10-2018 IPR016187 C-type lectin fold TO73_1168 0aca2dec42a6e406b2fee7455503d241 381 Pfam PF03781 Sulfatase-modifying factor enzyme 1 87 203 1.3E-7 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 TO73_1168 0aca2dec42a6e406b2fee7455503d241 381 Gene3D G3DSA:3.90.1580.10 75 241 3.5E-8 T 11-10-2018 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PIRSF PIRSF006615 2 511 8.1E-197 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 303 319 1.2E-91 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 412 433 1.2E-91 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 343 362 1.2E-91 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 256 275 1.2E-91 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 389 406 1.2E-91 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 239 255 1.2E-91 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 457 475 1.2E-91 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 276 295 1.2E-91 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 159 179 1.2E-91 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 SUPERFAMILY SSF55486 6 505 2.3E-109 T 11-10-2018 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 20 505 1.8E-111 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TO73_0114 01e7a8306c1b00f7b0d119d951be1562 511 Gene3D G3DSA:1.10.1370.30 1 509 5.5E-207 T 11-10-2018 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 ProSitePatterns PS00785 5'-nucleotidase signature 1. 28 40 - T 11-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 Pfam PF02872 5'-nucleotidase, C-terminal domain 331 492 1.0E-51 T 11-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 ProSitePatterns PS00786 5'-nucleotidase signature 2. 106 117 - T 11-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 SUPERFAMILY SSF56300 26 317 4.02E-89 T 11-10-2018 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 Gene3D G3DSA:3.60.21.10 26 330 1.6E-124 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 SUPERFAMILY SSF55816 328 530 3.27E-72 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 Pfam PF00149 Calcineurin-like phosphoesterase 29 239 7.3E-10 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 PRINTS PR01607 Apyrase family signature 465 484 2.8E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 PRINTS PR01607 Apyrase family signature 26 44 2.8E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 PRINTS PR01607 Apyrase family signature 267 287 2.8E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 PRINTS PR01607 Apyrase family signature 222 245 2.8E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 PRINTS PR01607 Apyrase family signature 388 411 2.8E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 PRINTS PR01607 Apyrase family signature 203 220 2.8E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0605 7a7de06b261498a2e2540409bd80f7a1 550 Gene3D G3DSA:3.90.780.10 331 532 1.8E-90 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TO73_0388 16d2064a3928b79ce0bc30981b0d5d84 182 Gene3D G3DSA:3.30.1440.10 1 182 1.5E-82 T 11-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0388 16d2064a3928b79ce0bc30981b0d5d84 182 Pfam PF00281 Ribosomal protein L5 27 83 2.5E-25 T 11-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0388 16d2064a3928b79ce0bc30981b0d5d84 182 SUPERFAMILY SSF55282 7 182 7.77E-74 T 11-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0388 16d2064a3928b79ce0bc30981b0d5d84 182 PIRSF PIRSF002161 3 182 2.0E-64 T 11-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0388 16d2064a3928b79ce0bc30981b0d5d84 182 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 4 182 43.417 T 11-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0388 16d2064a3928b79ce0bc30981b0d5d84 182 Pfam PF00673 ribosomal L5P family C-terminus 87 180 1.6E-38 T 11-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0388 16d2064a3928b79ce0bc30981b0d5d84 182 ProSitePatterns PS00358 Ribosomal protein L5 signature. 60 76 - T 11-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0491 49643b902dbefb8858016185818725cd 194 Pfam PF13662 Toprim domain 81 167 3.7E-23 T 11-10-2018 IPR006171 TOPRIM domain TO73_0491 49643b902dbefb8858016185818725cd 194 SUPERFAMILY SSF111304 1 194 6.54E-67 T 11-10-2018 IPR023627 Recombination protein RecR TO73_0491 49643b902dbefb8858016185818725cd 194 SMART SM00493 78 161 1.6E-8 T 11-10-2018 IPR006171 TOPRIM domain TO73_0491 49643b902dbefb8858016185818725cd 194 ProSitePatterns PS01300 RecR protein signature. 55 76 - T 11-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 TO73_0491 49643b902dbefb8858016185818725cd 194 Gene3D G3DSA:1.10.8.420 1 51 1.4E-13 T 11-10-2018 TO73_0491 49643b902dbefb8858016185818725cd 194 Pfam PF02132 RecR protein 46 76 9.9E-11 T 11-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger TO73_0491 49643b902dbefb8858016185818725cd 194 Gene3D G3DSA:3.40.1360.10 75 194 3.1E-41 T 11-10-2018 TO73_0491 49643b902dbefb8858016185818725cd 194 SMART SM00278 12 31 0.0052 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_0491 49643b902dbefb8858016185818725cd 194 Hamap MF_00017 Recombination protein RecR [recR]. 1 194 86.806 T 11-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TO73_0491 49643b902dbefb8858016185818725cd 194 TIGRFAM TIGR00615 recR: recombination protein RecR 2 192 7.8E-65 T 11-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TO73_0602 ec9cfbd68c86e9ccdb489fd0579c175f 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 306 3.6E-51 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_1855 996993213208878b7cd4075609fb70fd 528 Pfam PF00128 Alpha amylase, catalytic domain 25 367 2.6E-98 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TO73_1855 996993213208878b7cd4075609fb70fd 528 Gene3D G3DSA:3.90.400.10 102 172 2.8E-179 T 11-10-2018 TO73_1855 996993213208878b7cd4075609fb70fd 528 SMART SM00642 10 388 1.2E-144 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TO73_1855 996993213208878b7cd4075609fb70fd 528 Gene3D G3DSA:2.60.40.1180 464 528 3.3E-6 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta TO73_1855 996993213208878b7cd4075609fb70fd 528 SUPERFAMILY SSF51445 2 453 4.42E-147 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily TO73_1855 996993213208878b7cd4075609fb70fd 528 SUPERFAMILY SSF51011 458 527 4.32E-6 T 11-10-2018 TO73_1855 996993213208878b7cd4075609fb70fd 528 Gene3D G3DSA:3.20.20.80 2 451 2.8E-179 T 11-10-2018 TO73_1427 e7372c10225c680a978ed78420115759 470 Gene3D G3DSA:3.30.499.20 4 286 2.4E-92 T 11-10-2018 TO73_1427 e7372c10225c680a978ed78420115759 470 ProSitePatterns PS00450 Aconitase family signature 1. 338 354 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 9.4E-145 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 PRINTS PR00415 Aconitase family signature 119 132 4.2E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 PRINTS PR00415 Aconitase family signature 286 300 4.2E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 PRINTS PR00415 Aconitase family signature 342 353 4.2E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 PRINTS PR00415 Aconitase family signature 108 116 4.2E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 PRINTS PR00415 Aconitase family signature 209 222 4.2E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 PRINTS PR00415 Aconitase family signature 398 411 4.2E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 PRINTS PR00415 Aconitase family signature 195 208 4.2E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 PRINTS PR00415 Aconitase family signature 82 95 4.2E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 PRINTS PR00415 Aconitase family signature 133 148 4.2E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 Gene3D G3DSA:3.30.499.10 326 465 4.1E-48 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 SUPERFAMILY SSF53732 1 465 4.58E-155 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 ProSitePatterns PS01244 Aconitase family signature 2. 398 411 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 465 2.0E-187 T 11-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TO73_1427 e7372c10225c680a978ed78420115759 470 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 56.741 T 11-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TO73_2113 4ee26c9a1a9ba4c312edff173346d9eb 609 Pfam PF02653 Branched-chain amino acid transport system / permease component 223 574 5.6E-26 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_2207 01a79fb23cfc1ad9d1cb4b8d87ea0644 371 SUPERFAMILY SSF52402 4 246 4.85E-48 T 11-10-2018 TO73_2207 01a79fb23cfc1ad9d1cb4b8d87ea0644 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 3 350 39.217 T 11-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TO73_2207 01a79fb23cfc1ad9d1cb4b8d87ea0644 371 Gene3D G3DSA:2.40.30.10 281 356 3.0E-15 T 11-10-2018 TO73_2207 01a79fb23cfc1ad9d1cb4b8d87ea0644 371 Gene3D G3DSA:3.40.50.620 1 213 3.5E-76 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_2207 01a79fb23cfc1ad9d1cb4b8d87ea0644 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 4 349 1.0E-95 T 11-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TO73_2207 01a79fb23cfc1ad9d1cb4b8d87ea0644 371 Pfam PF03054 tRNA methyl transferase 4 349 1.5E-113 T 11-10-2018 TO73_2207 01a79fb23cfc1ad9d1cb4b8d87ea0644 371 Gene3D G3DSA:2.30.30.280 215 277 2.7E-16 T 11-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TO73_1815 c3f6d75f68f2558e41e71439a85b27db 161 Pfam PF00075 RNase H 7 145 5.5E-42 T 11-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 TO73_1815 c3f6d75f68f2558e41e71439a85b27db 161 Hamap MF_00042 Ribonuclease H [rnhA]. 5 154 37.008 T 11-10-2018 IPR022892 Ribonuclease HI GO:0004523 TO73_1815 c3f6d75f68f2558e41e71439a85b27db 161 Gene3D G3DSA:3.30.420.10 5 161 5.4E-57 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_1815 c3f6d75f68f2558e41e71439a85b27db 161 SUPERFAMILY SSF53098 7 146 1.77E-52 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_0336 f4135a8de22bdc6204d26b3925479d04 458 SUPERFAMILY SSF56176 5 211 7.48E-64 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TO73_0336 f4135a8de22bdc6204d26b3925479d04 458 Gene3D G3DSA:3.30.465.40 5 230 3.2E-68 T 11-10-2018 TO73_0336 f4135a8de22bdc6204d26b3925479d04 458 Gene3D G3DSA:1.10.45.10 410 449 1.2E-12 T 11-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TO73_0336 f4135a8de22bdc6204d26b3925479d04 458 Pfam PF01565 FAD binding domain 38 173 7.3E-37 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TO73_0336 f4135a8de22bdc6204d26b3925479d04 458 SUPERFAMILY SSF55103 214 450 5.72E-63 T 11-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TO73_0336 f4135a8de22bdc6204d26b3925479d04 458 Gene3D G3DSA:3.30.70.2740 331 409 9.6E-10 T 11-10-2018 TO73_0336 f4135a8de22bdc6204d26b3925479d04 458 Pfam PF02913 FAD linked oxidases, C-terminal domain 210 448 1.1E-58 T 11-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TO73_2141 acd8bd766f220cf50ca75541508151db 156 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TO73_2141 acd8bd766f220cf50ca75541508151db 156 Gene3D G3DSA:3.90.79.10 3 145 2.8E-27 T 11-10-2018 TO73_2141 acd8bd766f220cf50ca75541508151db 156 PRINTS PR00502 NUDIX hydrolase family signature 35 49 1.3E-7 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_2141 acd8bd766f220cf50ca75541508151db 156 PRINTS PR00502 NUDIX hydrolase family signature 49 64 1.3E-7 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_2141 acd8bd766f220cf50ca75541508151db 156 Pfam PF00293 NUDIX domain 8 126 7.4E-22 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TO73_2141 acd8bd766f220cf50ca75541508151db 156 SUPERFAMILY SSF55811 4 138 1.35E-25 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TO73_2875 414010d1593ac01d19d54bca3174b4a5 294 SMART SM00470 26 113 7.1E-32 T 11-10-2018 IPR003115 ParB/Sulfiredoxin TO73_2875 414010d1593ac01d19d54bca3174b4a5 294 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 28 141 4.3E-30 T 11-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TO73_2875 414010d1593ac01d19d54bca3174b4a5 294 SUPERFAMILY SSF109709 107 246 6.54E-18 T 11-10-2018 TO73_2875 414010d1593ac01d19d54bca3174b4a5 294 SUPERFAMILY SSF110849 25 147 7.5E-29 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TO73_2875 414010d1593ac01d19d54bca3174b4a5 294 Pfam PF02195 ParB-like nuclease domain 28 112 6.4E-23 T 11-10-2018 IPR003115 ParB/Sulfiredoxin TO73_2875 414010d1593ac01d19d54bca3174b4a5 294 Gene3D G3DSA:3.90.1530.30 38 99 2.8E-24 T 11-10-2018 TO73_2875 414010d1593ac01d19d54bca3174b4a5 294 Gene3D G3DSA:1.10.10.2830 155 248 6.6E-7 T 11-10-2018 TO73_2875 414010d1593ac01d19d54bca3174b4a5 294 Gene3D G3DSA:1.10.10.2830 100 154 1.2E-9 T 11-10-2018 TO73_1866 416f7a497002076d41b0e83ce78c9f60 343 Gene3D G3DSA:3.40.50.720 148 290 5.4E-135 T 11-10-2018 TO73_1866 416f7a497002076d41b0e83ce78c9f60 343 SUPERFAMILY SSF51735 142 314 5.0E-50 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1866 416f7a497002076d41b0e83ce78c9f60 343 Pfam PF00107 Zinc-binding dehydrogenase 178 296 7.4E-34 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TO73_1866 416f7a497002076d41b0e83ce78c9f60 343 SUPERFAMILY SSF50129 1 171 1.52E-55 T 11-10-2018 IPR011032 GroES-like superfamily TO73_1866 416f7a497002076d41b0e83ce78c9f60 343 SMART SM00829 10 340 8.2E-19 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TO73_1866 416f7a497002076d41b0e83ce78c9f60 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 134 2.2E-30 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TO73_1866 416f7a497002076d41b0e83ce78c9f60 343 Gene3D G3DSA:3.90.180.10 18 333 5.4E-135 T 11-10-2018 TO73_1167 71bae7a8684b641037224c082fe0f5b2 115 Gene3D G3DSA:1.20.1440.220 7 115 7.3E-8 T 11-10-2018 TO73_1167 71bae7a8684b641037224c082fe0f5b2 115 Pfam PF05635 23S rRNA-intervening sequence protein 6 105 2.2E-14 T 11-10-2018 IPR012657 23S rRNA-intervening sequence protein TO73_1167 71bae7a8684b641037224c082fe0f5b2 115 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 9 111 1.5E-8 T 11-10-2018 IPR012657 23S rRNA-intervening sequence protein TO73_1167 71bae7a8684b641037224c082fe0f5b2 115 SUPERFAMILY SSF158446 1 112 1.96E-16 T 11-10-2018 IPR036583 23S rRNA-intervening sequence superfamily TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 180 9.2E-4 T 11-10-2018 TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 SUPERFAMILY SSF51735 6 241 1.14E-77 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 Gene3D G3DSA:3.40.50.720 1 236 4.5E-78 T 11-10-2018 TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.0E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.0E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.0E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.0E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 2.0E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0921 230b4a41ae614e6e5a7e59d533a17498 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 238 6.5E-64 T 11-10-2018 TO73_0775 b662584ccba30f87a298e5ff9d5e675a 506 Pfam PF13692 Glycosyl transferases group 1 331 451 7.6E-21 T 11-10-2018 TO73_0775 b662584ccba30f87a298e5ff9d5e675a 506 Gene3D G3DSA:3.40.50.2000 302 452 1.4E-54 T 11-10-2018 TO73_0775 b662584ccba30f87a298e5ff9d5e675a 506 SUPERFAMILY SSF53756 124 499 6.73E-60 T 11-10-2018 TO73_0775 b662584ccba30f87a298e5ff9d5e675a 506 Pfam PF13439 Glycosyltransferase Family 4 143 305 5.0E-17 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TO73_0775 b662584ccba30f87a298e5ff9d5e675a 506 Gene3D G3DSA:3.40.50.2000 151 301 1.4E-54 T 11-10-2018 TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 SMART SM00322 60 125 2.7E-5 T 11-10-2018 IPR004087 K Homology domain GO:0003676 TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 35.966 T 11-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 200 2.4E-33 T 11-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.2E-82 T 11-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 Gene3D G3DSA:3.30.300.20 17 107 3.0E-30 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 11-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 SUPERFAMILY SSF54814 2 106 3.4E-37 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 SUPERFAMILY SSF54821 108 206 3.79E-35 T 11-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 Gene3D G3DSA:3.30.1140.32 108 208 2.1E-38 T 11-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0382 732da23032ecb17956bfc9083d4e18b6 239 Pfam PF07650 KH domain 39 110 2.6E-16 T 11-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_1947 26b9e3ca5f053c6201ed8759284b8841 148 Gene3D G3DSA:1.10.20.10 1 148 2.4E-63 T 11-10-2018 IPR009072 Histone-fold GO:0046982 TO73_1947 26b9e3ca5f053c6201ed8759284b8841 148 Pfam PF09123 Domain of unknown function (DUF1931) 8 145 4.8E-57 T 11-10-2018 IPR015207 Protein of unknown function DUF1931 TO73_1947 26b9e3ca5f053c6201ed8759284b8841 148 SUPERFAMILY SSF47113 1 148 6.7E-53 T 11-10-2018 IPR009072 Histone-fold GO:0046982 TO73_1633 717c18391697a9b1ff154a93b67061d2 275 Pfam PF08282 haloacid dehalogenase-like hydrolase 11 271 8.1E-23 T 11-10-2018 TO73_1633 717c18391697a9b1ff154a93b67061d2 275 ProSitePatterns PS01229 Hypothetical cof family signature 2. 225 247 - T 11-10-2018 TO73_1633 717c18391697a9b1ff154a93b67061d2 275 Gene3D G3DSA:3.30.1240.10 94 200 1.3E-36 T 11-10-2018 TO73_1633 717c18391697a9b1ff154a93b67061d2 275 Gene3D G3DSA:3.40.50.1000 8 268 1.3E-36 T 11-10-2018 IPR023214 HAD superfamily TO73_1633 717c18391697a9b1ff154a93b67061d2 275 SUPERFAMILY SSF56784 7 272 5.17E-38 T 11-10-2018 IPR036412 HAD-like superfamily TO73_0480 a56387bd2864e386ddc1e0657984585a 173 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 164 5.5E-38 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TO73_0480 a56387bd2864e386ddc1e0657984585a 173 PIRSF PIRSF006806 1 169 2.1E-34 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TO73_0480 a56387bd2864e386ddc1e0657984585a 173 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 164 5.0E-28 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TO73_0480 a56387bd2864e386ddc1e0657984585a 173 SUPERFAMILY SSF100950 2 170 2.93E-44 T 11-10-2018 IPR037171 NagB/RpiA transferase-like TO73_0480 a56387bd2864e386ddc1e0657984585a 173 Gene3D G3DSA:3.40.50.10420 1 173 2.8E-64 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TO73_0587 bff06adb8dcc4764b1a341880498b931 321 SUPERFAMILY SSF51261 166 314 1.36E-47 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_0587 bff06adb8dcc4764b1a341880498b931 321 SMART SM00257 17 61 2.3E-17 T 11-10-2018 IPR018392 LysM domain TO73_0587 bff06adb8dcc4764b1a341880498b931 321 Gene3D G3DSA:2.70.70.10 168 317 4.3E-44 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_0587 bff06adb8dcc4764b1a341880498b931 321 Pfam PF01551 Peptidase family M23 217 311 4.2E-27 T 11-10-2018 IPR016047 Peptidase M23 TO73_0587 bff06adb8dcc4764b1a341880498b931 321 Gene3D G3DSA:3.10.350.10 15 61 2.4E-18 T 11-10-2018 IPR036779 LysM domain superfamily TO73_0587 bff06adb8dcc4764b1a341880498b931 321 Pfam PF01476 LysM domain 18 60 1.2E-15 T 11-10-2018 IPR018392 LysM domain TO73_0587 bff06adb8dcc4764b1a341880498b931 321 SUPERFAMILY SSF54106 16 60 8.37E-12 T 11-10-2018 TO73_1652 87d7575e137a061a30994fb242708419 426 SUPERFAMILY SSF50249 62 134 4.54E-16 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1652 87d7575e137a061a30994fb242708419 426 Pfam PF07498 Rho termination factor, N-terminal domain 16 57 8.9E-12 T 11-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TO73_1652 87d7575e137a061a30994fb242708419 426 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 165 370 1.5E-22 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1652 87d7575e137a061a30994fb242708419 426 SMART SM00959 16 57 7.4E-11 T 11-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TO73_1652 87d7575e137a061a30994fb242708419 426 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 426 192.746 T 11-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TO73_1652 87d7575e137a061a30994fb242708419 426 SUPERFAMILY SSF68912 13 57 5.49E-8 T 11-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily TO73_1652 87d7575e137a061a30994fb242708419 426 TIGRFAM TIGR00767 rho: transcription termination factor Rho 14 423 1.4E-178 T 11-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TO73_1652 87d7575e137a061a30994fb242708419 426 Gene3D G3DSA:3.40.50.300 139 426 3.1E-125 T 11-10-2018 TO73_1652 87d7575e137a061a30994fb242708419 426 Gene3D G3DSA:2.40.50.140 11 138 1.1E-32 T 11-10-2018 TO73_1652 87d7575e137a061a30994fb242708419 426 SMART SM00382 176 362 2.8E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1652 87d7575e137a061a30994fb242708419 426 Pfam PF07497 Rho termination factor, RNA-binding domain 63 134 5.6E-22 T 11-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 TO73_1652 87d7575e137a061a30994fb242708419 426 SUPERFAMILY SSF52540 101 378 3.82E-68 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1646 446cc27aabe82dee0b3058967b86a9f3 221 Pfam PF14344 Domain of unknown function (DUF4397) 122 210 5.9E-19 T 11-10-2018 IPR025510 Domain of unknown function DUF4397 TO73_1646 446cc27aabe82dee0b3058967b86a9f3 221 Pfam PF14344 Domain of unknown function (DUF4397) 22 138 5.6E-31 T 11-10-2018 IPR025510 Domain of unknown function DUF4397 TO73_1294 6a6b6ff60d577a49c4660c2001a808fd 316 Pfam PF16868 NMT1-like family 25 313 1.8E-81 T 11-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TO73_1294 6a6b6ff60d577a49c4660c2001a808fd 316 Gene3D G3DSA:3.40.190.10 111 249 1.3E-116 T 11-10-2018 TO73_1294 6a6b6ff60d577a49c4660c2001a808fd 316 Gene3D G3DSA:3.40.190.10 25 313 1.3E-116 T 11-10-2018 TO73_1294 6a6b6ff60d577a49c4660c2001a808fd 316 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 9 313 1.2E-103 T 11-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TO73_1294 6a6b6ff60d577a49c4660c2001a808fd 316 SUPERFAMILY SSF53850 20 315 1.6E-82 T 11-10-2018 TO73_1431 f1f3fac14c7ffc01174963bded67cf6a 178 SUPERFAMILY SSF52980 4 157 8.58E-22 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1431 f1f3fac14c7ffc01174963bded67cf6a 178 Gene3D G3DSA:3.90.1570.10 1 176 2.2E-15 T 11-10-2018 TO73_1431 f1f3fac14c7ffc01174963bded67cf6a 178 Pfam PF05685 Putative restriction endonuclease 8 166 4.6E-33 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1044 bd0f64d11fe7b30afaa67313dccccb8f 247 PIRSF PIRSF000090 1 247 2.5E-65 T 11-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 TO73_1044 bd0f64d11fe7b30afaa67313dccccb8f 247 SMART SM00893 21 208 2.5E-40 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TO73_1044 bd0f64d11fe7b30afaa67313dccccb8f 247 Gene3D G3DSA:3.40.50.620 1 247 2.6E-68 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1044 bd0f64d11fe7b30afaa67313dccccb8f 247 SUPERFAMILY SSF52402 1 230 4.88E-61 T 11-10-2018 TO73_1044 bd0f64d11fe7b30afaa67313dccccb8f 247 Pfam PF01012 Electron transfer flavoprotein domain 30 202 4.7E-37 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TO73_2034 91338fc53828f6f974068d728f62524b 296 SUPERFAMILY SSF110849 54 140 6.1E-7 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TO73_2034 91338fc53828f6f974068d728f62524b 296 Pfam PF13224 Domain of unknown function (DUF4032) 200 276 6.5E-6 T 11-10-2018 IPR025111 Domain of unknown function DUF4032 TO73_0607 ead1663d0b543a8e9062805b24e513d8 231 Gene3D G3DSA:1.10.760.10 30 87 4.5E-8 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0607 ead1663d0b543a8e9062805b24e513d8 231 Pfam PF00034 Cytochrome c 106 193 8.1E-7 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0607 ead1663d0b543a8e9062805b24e513d8 231 SUPERFAMILY SSF46626 29 98 2.2E-12 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0607 ead1663d0b543a8e9062805b24e513d8 231 SUPERFAMILY SSF46626 107 209 4.58E-20 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0607 ead1663d0b543a8e9062805b24e513d8 231 Gene3D G3DSA:1.10.760.10 105 231 1.5E-36 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0607 ead1663d0b543a8e9062805b24e513d8 231 Pfam PF09098 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding 31 99 4.0E-6 T 11-10-2018 IPR015182 Quinohemoprotein amine dehydrogenase, alpha subunit, haem binding domain TO73_2001 0f2dbc3a9d691deab46435b4e6a6bf56 269 Pfam PF00899 ThiF family 10 248 3.0E-68 T 11-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TO73_2001 0f2dbc3a9d691deab46435b4e6a6bf56 269 Gene3D G3DSA:3.40.50.720 3 258 2.8E-96 T 11-10-2018 TO73_2001 0f2dbc3a9d691deab46435b4e6a6bf56 269 SUPERFAMILY SSF69572 2 260 1.12E-98 T 11-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TO73_0573 9f99590b9f25d7ae1cfd57383cd3293d 187 Gene3D G3DSA:3.40.50.10420 33 186 2.1E-26 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TO73_0573 9f99590b9f25d7ae1cfd57383cd3293d 187 SUPERFAMILY SSF100950 30 185 2.3E-25 T 11-10-2018 IPR037171 NagB/RpiA transferase-like TO73_0573 9f99590b9f25d7ae1cfd57383cd3293d 187 Pfam PF02589 LUD domain 93 183 3.9E-13 T 11-10-2018 IPR003741 LUD domain TO73_1567 a10c5e453874acd35db29b2859bb02e1 530 PIRSF PIRSF015855 3 420 1.5E-109 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TO73_1567 a10c5e453874acd35db29b2859bb02e1 530 Pfam PF01555 DNA methylase 59 394 1.2E-45 T 11-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 TO73_1567 a10c5e453874acd35db29b2859bb02e1 530 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 62 68 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TO73_1567 a10c5e453874acd35db29b2859bb02e1 530 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 329 351 8.0E-21 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TO73_1567 a10c5e453874acd35db29b2859bb02e1 530 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 354 368 8.0E-21 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TO73_1567 a10c5e453874acd35db29b2859bb02e1 530 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 59 71 8.0E-21 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TO73_1567 a10c5e453874acd35db29b2859bb02e1 530 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 114 133 8.0E-21 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TO73_1567 a10c5e453874acd35db29b2859bb02e1 530 SUPERFAMILY SSF53335 34 400 2.07E-72 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1463 c73aef29e092d1354158585d61a07c71 147 Pfam PF03350 Uncharacterized protein family, UPF0114 7 114 1.3E-23 T 11-10-2018 IPR005134 Uncharacterised protein family UPF0114 TO73_1463 c73aef29e092d1354158585d61a07c71 147 PIRSF PIRSF026509 2 147 4.8E-25 T 11-10-2018 IPR005134 Uncharacterised protein family UPF0114 TO73_2864 e8979ccaf6a6e184b8cd2cd9816e85ff 365 Gene3D G3DSA:3.40.50.300 49 280 1.5E-17 T 11-10-2018 TO73_2864 e8979ccaf6a6e184b8cd2cd9816e85ff 365 SUPERFAMILY SSF52540 50 251 1.0E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2725 5b00dbf850087013c50a484a186e3c7f 419 Pfam PF12323 Helix-turn-helix domain 1 47 2.0E-13 T 11-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain TO73_2725 5b00dbf850087013c50a484a186e3c7f 419 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 254 326 2.6E-11 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_2725 5b00dbf850087013c50a484a186e3c7f 419 Pfam PF07282 Putative transposase DNA-binding domain 299 367 5.9E-21 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_2725 5b00dbf850087013c50a484a186e3c7f 419 Pfam PF01385 Probable transposase 172 286 7.2E-27 T 11-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TO73_1579 d2f7486879974822be1f3d90156cdfeb 406 SUPERFAMILY SSF56762 32 406 1.96E-133 T 11-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1579 d2f7486879974822be1f3d90156cdfeb 406 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 15 406 48.475 T 11-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1579 d2f7486879974822be1f3d90156cdfeb 406 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 22 406 2.5E-169 T 11-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1579 d2f7486879974822be1f3d90156cdfeb 406 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 59 70 - T 11-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1579 d2f7486879974822be1f3d90156cdfeb 406 Gene3D G3DSA:1.10.645.20 23 406 1.1E-172 T 11-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1579 d2f7486879974822be1f3d90156cdfeb 406 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 136 406 1.2E-112 T 11-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 SUPERFAMILY SSF56327 156 323 5.56E-60 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 SUPERFAMILY SSF51735 1 155 3.11E-46 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 Hamap MF_01517 Malate dehydrogenase [mdh]. 1 325 55.67 T 11-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 156 323 1.5E-40 T 11-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 Gene3D G3DSA:3.90.110.10 155 327 2.2E-64 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 152 1.7E-38 T 11-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 PIRSF PIRSF000102 1 325 8.8E-73 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 3 320 3.8E-155 T 11-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 155 167 - T 11-10-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TO73_1768 76a5253424e3b069843ed39fb5aee8c2 327 Gene3D G3DSA:3.40.50.720 1 154 1.9E-59 T 11-10-2018 TO73_0731 d5ee2c286ce153bbd16264c6951153ec 321 Pfam PF01699 Sodium/calcium exchanger protein 3 146 3.2E-14 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TO73_0731 d5ee2c286ce153bbd16264c6951153ec 321 Pfam PF01699 Sodium/calcium exchanger protein 177 314 4.4E-12 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TO73_0731 d5ee2c286ce153bbd16264c6951153ec 321 Gene3D G3DSA:1.20.1420.30 33 286 8.3E-42 T 11-10-2018 TO73_0731 d5ee2c286ce153bbd16264c6951153ec 321 Gene3D G3DSA:1.20.58.1130 8 203 8.3E-42 T 11-10-2018 TO73_0017 03661d616df09cf7cfb266efcc6c4422 226 Gene3D G3DSA:2.40.30.90 138 226 1.1E-29 T 11-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TO73_0017 03661d616df09cf7cfb266efcc6c4422 226 PIRSF PIRSF006779 1 226 1.3E-49 T 11-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TO73_0017 03661d616df09cf7cfb266efcc6c4422 226 Gene3D G3DSA:3.40.50.10790 1 137 1.5E-43 T 11-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TO73_0017 03661d616df09cf7cfb266efcc6c4422 226 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 1 223 7.5E-58 T 11-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TO73_0017 03661d616df09cf7cfb266efcc6c4422 226 SUPERFAMILY SSF102522 1 138 1.57E-36 T 11-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TO73_0017 03661d616df09cf7cfb266efcc6c4422 226 SUPERFAMILY SSF101852 145 225 5.1E-19 T 11-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TO73_0854 93aa2e751376c2c0857e38845895f8f8 269 SUPERFAMILY SSF51556 40 248 9.53E-65 T 11-10-2018 IPR032466 Metal-dependent hydrolase TO73_0854 93aa2e751376c2c0857e38845895f8f8 269 Pfam PF01979 Amidohydrolase family 36 225 2.4E-10 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TO73_0854 93aa2e751376c2c0857e38845895f8f8 269 Gene3D G3DSA:3.20.20.140 40 249 8.9E-73 T 11-10-2018 TO73_1206 3460690cf62362426fc3d86de09db031 233 SMART SM00530 28 91 7.6E-7 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TO73_1206 3460690cf62362426fc3d86de09db031 233 Gene3D G3DSA:1.10.260.40 27 93 5.5E-8 T 11-10-2018 TO73_1206 3460690cf62362426fc3d86de09db031 233 Pfam PF00717 Peptidase S24-like 146 210 2.0E-8 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TO73_1206 3460690cf62362426fc3d86de09db031 233 Pfam PF01381 Helix-turn-helix 30 91 2.4E-6 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TO73_1206 3460690cf62362426fc3d86de09db031 233 SUPERFAMILY SSF51306 109 228 6.28E-13 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TO73_1206 3460690cf62362426fc3d86de09db031 233 SUPERFAMILY SSF47413 25 97 1.28E-7 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TO73_1206 3460690cf62362426fc3d86de09db031 233 Gene3D G3DSA:2.10.109.10 94 232 1.4E-15 T 11-10-2018 TO73_1271 5e554e3c9fcedf3c668b6cd75ca15a94 68 Pfam PF05163 DinB family 3 63 2.2E-9 T 11-10-2018 IPR007837 DNA damage-inducible protein DinB TO73_1271 5e554e3c9fcedf3c668b6cd75ca15a94 68 SUPERFAMILY SSF109854 24 63 4.03E-7 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TO73_1271 5e554e3c9fcedf3c668b6cd75ca15a94 68 Gene3D G3DSA:1.20.120.450 7 66 6.9E-8 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TO73_1611 2d97f2b8ddcda0c098a9b27fc6c7ebfc 224 SMART SM00849 8 187 4.9E-8 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_1611 2d97f2b8ddcda0c098a9b27fc6c7ebfc 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 223 36.636 T 11-10-2018 IPR022877 Protein of unknown funcion UPF0173 TO73_1611 2d97f2b8ddcda0c098a9b27fc6c7ebfc 224 Gene3D G3DSA:3.60.15.10 2 222 2.8E-71 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_1611 2d97f2b8ddcda0c098a9b27fc6c7ebfc 224 SUPERFAMILY SSF56281 2 212 1.57E-37 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_1611 2d97f2b8ddcda0c098a9b27fc6c7ebfc 224 Pfam PF13483 Beta-lactamase superfamily domain 3 187 3.0E-23 T 11-10-2018 TO73_1098 4fe673904c1a3bdd9bc90199a442471f 247 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 245 55.387 T 11-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1098 4fe673904c1a3bdd9bc90199a442471f 247 SUPERFAMILY SSF51351 2 244 3.14E-86 T 11-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1098 4fe673904c1a3bdd9bc90199a442471f 247 Gene3D G3DSA:3.20.20.70 1 247 1.7E-103 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1098 4fe673904c1a3bdd9bc90199a442471f 247 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 2 235 8.3E-52 T 11-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1098 4fe673904c1a3bdd9bc90199a442471f 247 ProSitePatterns PS00171 Triosephosphate isomerase active site. 161 171 - T 11-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1098 4fe673904c1a3bdd9bc90199a442471f 247 Pfam PF00121 Triosephosphate isomerase 2 242 1.3E-87 T 11-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_0717 4c423582c7a639cc50845de701b6dd25 414 SUPERFAMILY SSF53383 20 403 1.6E-133 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_0717 4c423582c7a639cc50845de701b6dd25 414 Pfam PF00202 Aminotransferase class-III 31 400 1.3E-114 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0717 4c423582c7a639cc50845de701b6dd25 414 Gene3D G3DSA:3.40.640.10 62 306 4.6E-168 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_0717 4c423582c7a639cc50845de701b6dd25 414 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 258 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0717 4c423582c7a639cc50845de701b6dd25 414 PIRSF PIRSF000521 172 405 2.1E-41 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0717 4c423582c7a639cc50845de701b6dd25 414 PIRSF PIRSF000521 124 157 1.7 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0717 4c423582c7a639cc50845de701b6dd25 414 PIRSF PIRSF000521 26 130 1.3E-10 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_0717 4c423582c7a639cc50845de701b6dd25 414 Gene3D G3DSA:3.90.1150.10 7 402 4.6E-168 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_0448 e3fe6e7078c39ebd4079dda609d69266 98 SUPERFAMILY SSF81301 2 93 2.45E-23 T 11-10-2018 TO73_0448 e3fe6e7078c39ebd4079dda609d69266 98 Pfam PF01909 Nucleotidyltransferase domain 13 88 5.6E-15 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TO73_0448 e3fe6e7078c39ebd4079dda609d69266 98 Gene3D G3DSA:3.30.460.10 2 97 3.1E-19 T 11-10-2018 TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 Gene3D G3DSA:3.30.360.10 121 309 5.7E-143 T 11-10-2018 TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 SUPERFAMILY SSF51735 1 149 3.2E-41 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 132 312 1.8E-52 T 11-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 1 326 7.7E-119 T 11-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 PIRSF PIRSF000148 1 328 7.3E-120 T 11-10-2018 TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 326 34.184 T 11-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 SMART SM00859 1 114 1.5E-34 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 1 111 6.4E-27 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 SUPERFAMILY SSF55347 122 313 4.46E-72 T 11-10-2018 TO73_1359 5702b9f95e016fdb745f31a215cac0e4 329 Gene3D G3DSA:3.40.50.720 1 323 5.7E-143 T 11-10-2018 TO73_1809 7aa4676bfd2d653bd63142984d93a880 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 117 1.4E-9 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TO73_1809 7aa4676bfd2d653bd63142984d93a880 125 Gene3D G3DSA:3.10.180.10 4 124 1.6E-29 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_1809 7aa4676bfd2d653bd63142984d93a880 125 SUPERFAMILY SSF54593 8 122 7.12E-28 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 Gene3D G3DSA:4.10.640.10 1 89 1.2E-35 T 11-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 Pfam PF01084 Ribosomal protein S18 34 80 3.6E-23 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 34 83 4.0E-21 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 15 85 20.599 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 SUPERFAMILY SSF46911 14 85 1.83E-24 T 11-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 PRINTS PR00974 Ribosomal protein S18 family signature 50 57 1.5E-18 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 PRINTS PR00974 Ribosomal protein S18 family signature 58 72 1.5E-18 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 PRINTS PR00974 Ribosomal protein S18 family signature 72 82 1.5E-18 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 PRINTS PR00974 Ribosomal protein S18 family signature 40 50 1.5E-18 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 TIGRFAM TIGR00165 S18: ribosomal protein bS18 26 85 7.7E-22 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0128 418dc5d88d40b56865a209e0242aecaf 89 ProSitePatterns PS00057 Ribosomal protein S18 signature. 33 56 - T 11-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_2098 d98e5d587de98385f55f48e7cfe7b161 257 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 172 182 - T 11-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TO73_2098 d98e5d587de98385f55f48e7cfe7b161 257 Gene3D G3DSA:3.40.50.1860 7 242 7.1E-76 T 11-10-2018 TO73_2098 d98e5d587de98385f55f48e7cfe7b161 257 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 11-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TO73_2098 d98e5d587de98385f55f48e7cfe7b161 257 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 239 5.4E-61 T 11-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TO73_2098 d98e5d587de98385f55f48e7cfe7b161 257 Gene3D G3DSA:3.40.50.1860 97 198 7.1E-76 T 11-10-2018 TO73_2098 d98e5d587de98385f55f48e7cfe7b161 257 Hamap MF_00258 Glutamate racemase [murI]. 6 246 33.154 T 11-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TO73_2098 d98e5d587de98385f55f48e7cfe7b161 257 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 204 7.3E-30 T 11-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TO73_2098 d98e5d587de98385f55f48e7cfe7b161 257 SUPERFAMILY SSF53681 109 241 3.92E-33 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TO73_2098 d98e5d587de98385f55f48e7cfe7b161 257 SUPERFAMILY SSF53681 7 107 3.92E-35 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 Gene3D G3DSA:3.10.350.10 102 150 1.6E-11 T 11-10-2018 IPR036779 LysM domain superfamily TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 Gene3D G3DSA:3.10.350.10 160 210 5.2E-6 T 11-10-2018 IPR036779 LysM domain superfamily TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 Gene3D G3DSA:3.10.350.10 37 96 4.1E-14 T 11-10-2018 IPR036779 LysM domain superfamily TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 SUPERFAMILY SSF54106 105 150 9.16E-8 T 11-10-2018 TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 Pfam PF01476 LysM domain 46 88 1.7E-11 T 11-10-2018 IPR018392 LysM domain TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 Pfam PF01476 LysM domain 162 198 9.5E-6 T 11-10-2018 IPR018392 LysM domain TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 Pfam PF01476 LysM domain 106 150 7.1E-8 T 11-10-2018 IPR018392 LysM domain TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 Pfam PF01551 Peptidase family M23 294 389 3.3E-35 T 11-10-2018 IPR016047 Peptidase M23 TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 Gene3D G3DSA:2.70.70.10 238 394 1.1E-50 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 SUPERFAMILY SSF54106 43 88 6.28E-10 T 11-10-2018 TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 SMART SM00257 105 150 1.6E-7 T 11-10-2018 IPR018392 LysM domain TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 SMART SM00257 157 201 0.3 T 11-10-2018 IPR018392 LysM domain TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 SMART SM00257 45 88 2.9E-9 T 11-10-2018 IPR018392 LysM domain TO73_1651 d56404cf35ef7f9f22b5d27152567c3a 394 SUPERFAMILY SSF51261 221 393 5.75E-58 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_0590 5c4443a06f90d22716fe8ae6afb3653e 329 Pfam PF07687 Peptidase dimerisation domain 136 232 8.7E-10 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain TO73_0590 5c4443a06f90d22716fe8ae6afb3653e 329 Gene3D G3DSA:3.30.70.360 135 244 7.5E-38 T 11-10-2018 TO73_0590 5c4443a06f90d22716fe8ae6afb3653e 329 Gene3D G3DSA:3.40.630.10 41 312 7.5E-38 T 11-10-2018 TO73_0590 5c4443a06f90d22716fe8ae6afb3653e 329 Pfam PF01546 Peptidase family M20/M25/M40 46 324 1.4E-13 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 TO73_0590 5c4443a06f90d22716fe8ae6afb3653e 329 SUPERFAMILY SSF53187 30 326 2.13E-28 T 11-10-2018 TO73_0590 5c4443a06f90d22716fe8ae6afb3653e 329 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 45 54 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TO73_0590 5c4443a06f90d22716fe8ae6afb3653e 329 SUPERFAMILY SSF55031 136 246 3.14E-14 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TO73_1847 716b8166a65a09469c4e94c715ff5554 332 Gene3D G3DSA:3.40.50.720 4 303 1.1E-102 T 11-10-2018 TO73_1847 716b8166a65a09469c4e94c715ff5554 332 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 173 195 - T 11-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TO73_1847 716b8166a65a09469c4e94c715ff5554 332 SUPERFAMILY SSF55347 132 290 2.29E-40 T 11-10-2018 TO73_1847 716b8166a65a09469c4e94c715ff5554 332 Gene3D G3DSA:3.30.360.10 138 286 1.1E-102 T 11-10-2018 TO73_1847 716b8166a65a09469c4e94c715ff5554 332 Pfam PF00742 Homoserine dehydrogenase 135 303 1.8E-49 T 11-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TO73_1847 716b8166a65a09469c4e94c715ff5554 332 PIRSF PIRSF036497 1 312 1.6E-77 T 11-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TO73_1847 716b8166a65a09469c4e94c715ff5554 332 SUPERFAMILY SSF51735 1 149 3.55E-24 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1847 716b8166a65a09469c4e94c715ff5554 332 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 114 4.8E-11 T 11-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TO73_1812 774e78c135f9a7844c99d9a90f0b4e28 458 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 334 414 3.7E-15 T 11-10-2018 IPR023885 4Fe4S-binding SPASM domain TO73_1812 774e78c135f9a7844c99d9a90f0b4e28 458 Gene3D G3DSA:3.20.20.70 95 446 1.4E-51 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1812 774e78c135f9a7844c99d9a90f0b4e28 458 SUPERFAMILY SSF102114 98 409 1.96E-37 T 11-10-2018 TO73_1812 774e78c135f9a7844c99d9a90f0b4e28 458 Pfam PF13353 4Fe-4S single cluster domain 105 226 7.1E-8 T 11-10-2018 TO73_1812 774e78c135f9a7844c99d9a90f0b4e28 458 Pfam PF04055 Radical SAM superfamily 102 239 6.3E-15 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_1482 818ad4e810a6f855cce61635306af046 208 Pfam PF00583 Acetyltransferase (GNAT) family 47 179 2.9E-15 T 11-10-2018 IPR000182 GNAT domain TO73_1482 818ad4e810a6f855cce61635306af046 208 Gene3D G3DSA:3.40.630.30 2 200 2.3E-38 T 11-10-2018 TO73_1482 818ad4e810a6f855cce61635306af046 208 SUPERFAMILY SSF55729 2 185 5.63E-28 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_1627 f6a733617a2edbd524f048acfa05fc7a 224 SUPERFAMILY SSF161098 2 212 4.32E-48 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1627 f6a733617a2edbd524f048acfa05fc7a 224 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 215 1.3E-66 T 11-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 TO73_1627 f6a733617a2edbd524f048acfa05fc7a 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 217 9.2E-18 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1627 f6a733617a2edbd524f048acfa05fc7a 224 Gene3D G3DSA:1.10.3720.10 1 219 2.9E-55 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2123 0d8a48eec009a4c17154dc6b9bcc5aea 319 Gene3D G3DSA:1.25.40.10 183 311 6.1E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2123 0d8a48eec009a4c17154dc6b9bcc5aea 319 SUPERFAMILY SSF48452 225 294 3.96E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1818 6f68728e9ceb2afbbe97517b8a5caf11 131 SUPERFAMILY SSF143592 2 127 5.49E-50 T 11-10-2018 IPR036828 TTHA1528-like superfamily TO73_1818 6f68728e9ceb2afbbe97517b8a5caf11 131 Gene3D G3DSA:3.40.1530.10 1 131 4.4E-58 T 11-10-2018 IPR036828 TTHA1528-like superfamily TO73_1818 6f68728e9ceb2afbbe97517b8a5caf11 131 Pfam PF11432 Protein of unknown function (DUF3197) 15 126 9.0E-44 T 11-10-2018 IPR024443 Domain of unknown function DUF3197 TO73_0436 1e33ea9ce556b1b6c8a2433cc917fcff 134 SUPERFAMILY SSF88723 2 112 5.56E-10 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_0436 1e33ea9ce556b1b6c8a2433cc917fcff 134 Pfam PF13470 PIN domain 2 106 2.4E-9 T 11-10-2018 IPR002716 PIN domain TO73_2387 dafadcbc24fab19fad4ad58d632e4814 102 Pfam PF12836 Helix-hairpin-helix motif 44 101 1.2E-20 T 11-10-2018 TO73_2387 dafadcbc24fab19fad4ad58d632e4814 102 SUPERFAMILY SSF81585 35 101 2.09E-22 T 11-10-2018 TO73_2387 dafadcbc24fab19fad4ad58d632e4814 102 Gene3D G3DSA:1.10.150.320 28 102 3.0E-31 T 11-10-2018 TO73_2387 dafadcbc24fab19fad4ad58d632e4814 102 SMART SM00278 80 99 0.79 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_2387 dafadcbc24fab19fad4ad58d632e4814 102 SMART SM00278 54 73 0.0096 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TO73_0570 e86f90d3a0cc6f2721b7417dcea7d7fa 257 Pfam PF00069 Protein kinase domain 15 244 3.7E-34 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TO73_0570 e86f90d3a0cc6f2721b7417dcea7d7fa 257 Gene3D G3DSA:1.10.510.10 7 254 4.2E-52 T 11-10-2018 TO73_0570 e86f90d3a0cc6f2721b7417dcea7d7fa 257 SUPERFAMILY SSF56112 8 253 2.97E-54 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily TO73_0570 e86f90d3a0cc6f2721b7417dcea7d7fa 257 SMART SM00220 15 257 3.7E-34 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TO73_0570 e86f90d3a0cc6f2721b7417dcea7d7fa 257 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 125 137 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TO73_2827 13d1246f8bec699fe7b10a47375c6999 261 Pfam PF00005 ABC transporter 18 164 1.2E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_2827 13d1246f8bec699fe7b10a47375c6999 261 SUPERFAMILY SSF52540 2 224 3.82E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2827 13d1246f8bec699fe7b10a47375c6999 261 SMART SM00382 26 211 1.1E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2827 13d1246f8bec699fe7b10a47375c6999 261 Gene3D G3DSA:3.40.50.300 1 243 7.8E-62 T 11-10-2018 TO73_1404 cf0775ae9dbc6ab18b138cdb5356d60e 211 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 7 210 8.0E-42 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TO73_1404 cf0775ae9dbc6ab18b138cdb5356d60e 211 Pfam PF01168 Alanine racemase, N-terminal domain 9 210 4.6E-22 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TO73_1404 cf0775ae9dbc6ab18b138cdb5356d60e 211 SUPERFAMILY SSF51419 3 209 3.79E-61 T 11-10-2018 IPR029066 PLP-binding barrel TO73_1404 cf0775ae9dbc6ab18b138cdb5356d60e 211 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 1 211 26.203 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TO73_1404 cf0775ae9dbc6ab18b138cdb5356d60e 211 Gene3D G3DSA:3.20.20.10 1 211 3.7E-67 T 11-10-2018 IPR029066 PLP-binding barrel TO73_1404 cf0775ae9dbc6ab18b138cdb5356d60e 211 PIRSF PIRSF004848 2 211 6.5E-54 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TO73_2019 b6d821020de047dd35dbed3fe062c2a1 312 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 241 2.3E-53 T 11-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2019 b6d821020de047dd35dbed3fe062c2a1 312 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 308 14.51 T 11-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2019 b6d821020de047dd35dbed3fe062c2a1 312 SUPERFAMILY SSF55120 3 243 4.48E-62 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_2019 b6d821020de047dd35dbed3fe062c2a1 312 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 22 154 6.7E-39 T 11-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TO73_1065 d9f0aba9d7f0e5dfbd52e6deb487c30c 286 Gene3D G3DSA:3.40.50.10170 11 158 6.7E-42 T 11-10-2018 TO73_1065 d9f0aba9d7f0e5dfbd52e6deb487c30c 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 13 282 8.1E-67 T 11-10-2018 IPR003797 DegV TO73_1065 d9f0aba9d7f0e5dfbd52e6deb487c30c 286 SUPERFAMILY SSF82549 11 283 1.41E-60 T 11-10-2018 TO73_1065 d9f0aba9d7f0e5dfbd52e6deb487c30c 286 Gene3D G3DSA:3.30.1180.10 160 284 1.5E-18 T 11-10-2018 TO73_1065 d9f0aba9d7f0e5dfbd52e6deb487c30c 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 12 283 6.9E-63 T 11-10-2018 IPR003797 DegV TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 263 2.1E-79 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 Gene3D G3DSA:3.40.50.800 394 505 4.4E-37 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 164 176 2.0E-59 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 441 460 2.0E-59 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 185 202 2.0E-59 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 2.0E-59 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 217 234 2.0E-59 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 234 244 2.0E-59 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 356 368 2.0E-59 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 505 49.3 T 11-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 SUPERFAMILY SSF55681 6 404 8.16E-126 T 11-10-2018 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 184 374 4.9E-11 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 Pfam PF03129 Anticodon binding domain 401 503 2.9E-28 T 11-10-2018 IPR004154 Anticodon-binding TO73_1362 215b26fc28c7f6500e7a4e3c07dd718e 506 SUPERFAMILY SSF52954 388 504 2.57E-29 T 11-10-2018 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 Gene3D G3DSA:3.30.70.1660 131 358 6.3E-90 T 11-10-2018 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 28 366 2.2E-129 T 11-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 SUPERFAMILY SSF75620 37 366 1.44E-119 T 11-10-2018 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 Pfam PF03462 PCRF domain 36 221 4.3E-54 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 Gene3D G3DSA:1.20.58.410 18 124 8.4E-38 T 11-10-2018 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 7 366 35.401 T 11-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 246 262 - T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 SMART SM00937 87 196 3.8E-41 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 Pfam PF00472 RF-1 domain 230 338 1.7E-36 T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TO73_1968 2eb655a3154dc0d84e0d93f674c27ed4 378 Gene3D G3DSA:3.30.160.20 227 322 6.3E-90 T 11-10-2018 TO73_1828 4e4a70216b548399bf8cfd8876ad1ed2 351 SUPERFAMILY SSF55103 132 258 6.1E-6 T 11-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TO73_1828 4e4a70216b548399bf8cfd8876ad1ed2 351 Pfam PF01565 FAD binding domain 2 131 7.8E-25 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TO73_1828 4e4a70216b548399bf8cfd8876ad1ed2 351 Gene3D G3DSA:3.30.465.40 1 188 1.5E-34 T 11-10-2018 TO73_1828 4e4a70216b548399bf8cfd8876ad1ed2 351 SUPERFAMILY SSF56176 2 170 7.27E-35 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TO73_2336 d27ac9fc6afc527cbcc053af5c89578f 98 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 85 16.303 T 11-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_2336 d27ac9fc6afc527cbcc053af5c89578f 98 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 65 4.7E-14 T 11-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_2336 d27ac9fc6afc527cbcc053af5c89578f 98 Pfam PF00830 Ribosomal L28 family 3 65 2.0E-11 T 11-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_2336 d27ac9fc6afc527cbcc053af5c89578f 98 Gene3D G3DSA:1.10.20.50 46 89 7.5E-26 T 11-10-2018 TO73_2336 d27ac9fc6afc527cbcc053af5c89578f 98 SUPERFAMILY SSF143800 1 95 5.69E-18 T 11-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_2336 d27ac9fc6afc527cbcc053af5c89578f 98 Gene3D G3DSA:2.20.150.30 1 45 1.1E-25 T 11-10-2018 TO73_0932 8974b3a44c039b25e4024ddf4e1f9855 135 Gene3D G3DSA:3.10.129.10 1 135 9.8E-45 T 11-10-2018 TO73_0932 8974b3a44c039b25e4024ddf4e1f9855 135 SUPERFAMILY SSF54637 3 133 6.21E-38 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_0932 8974b3a44c039b25e4024ddf4e1f9855 135 Pfam PF01575 MaoC like domain 10 107 2.1E-22 T 11-10-2018 IPR002539 MaoC-like dehydratase domain TO73_2142 ebd69cc045c8f0bae152adde2471f240 354 Pfam PF00472 RF-1 domain 208 316 5.2E-40 T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TO73_2142 ebd69cc045c8f0bae152adde2471f240 354 SMART SM00937 59 174 3.5E-53 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 TO73_2142 ebd69cc045c8f0bae152adde2471f240 354 Gene3D G3DSA:3.30.160.20 206 286 5.6E-95 T 11-10-2018 TO73_2142 ebd69cc045c8f0bae152adde2471f240 354 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 223 239 - T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TO73_2142 ebd69cc045c8f0bae152adde2471f240 354 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 352 1.4E-142 T 11-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TO73_2142 ebd69cc045c8f0bae152adde2471f240 354 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 352 37.618 T 11-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TO73_2142 ebd69cc045c8f0bae152adde2471f240 354 Pfam PF03462 PCRF domain 8 199 2.7E-71 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 TO73_2142 ebd69cc045c8f0bae152adde2471f240 354 SUPERFAMILY SSF75620 8 348 1.12E-130 T 11-10-2018 TO73_2142 ebd69cc045c8f0bae152adde2471f240 354 Gene3D G3DSA:3.30.70.1660 108 335 5.6E-95 T 11-10-2018 TO73_0133 baf32f67b9137b9b3be5d29406233a09 323 Pfam PF04055 Radical SAM superfamily 92 253 1.1E-13 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_0133 baf32f67b9137b9b3be5d29406233a09 323 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 37 74 6.9E-10 T 11-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TO73_0133 baf32f67b9137b9b3be5d29406233a09 323 Gene3D G3DSA:3.20.20.70 82 292 7.7E-19 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0133 baf32f67b9137b9b3be5d29406233a09 323 TIGRFAM TIGR00510 lipA: lipoyl synthase 37 320 7.3E-119 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TO73_0133 baf32f67b9137b9b3be5d29406233a09 323 SUPERFAMILY SSF102114 52 320 6.28E-63 T 11-10-2018 TO73_0133 baf32f67b9137b9b3be5d29406233a09 323 PIRSF PIRSF005963 8 323 4.4E-143 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TO73_0133 baf32f67b9137b9b3be5d29406233a09 323 Hamap MF_00206 Lipoyl synthase [lipA]. 39 323 140.056 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TO73_0133 baf32f67b9137b9b3be5d29406233a09 323 SMART SM00729 85 295 1.1E-10 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.1E-35 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00097 Anthranilate synthase component II signature 166 179 1.1E-35 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00097 Anthranilate synthase component II signature 120 132 1.1E-35 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00097 Anthranilate synthase component II signature 75 86 1.1E-35 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00097 Anthranilate synthase component II signature 100 108 1.1E-35 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00097 Anthranilate synthase component II signature 48 57 1.1E-35 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 2.5E-7 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 2.5E-7 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 Gene3D G3DSA:3.40.50.880 1 189 1.8E-62 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 188 5.7E-72 T 11-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 Pfam PF00117 Glutamine amidotransferase class-I 4 187 1.8E-49 T 11-10-2018 IPR017926 Glutamine amidotransferase TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 2.4E-13 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 2.4E-13 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 2.4E-13 T 11-10-2018 TO73_2028 d069d666b1b765bb4425bcbb02a241e0 193 SUPERFAMILY SSF52317 2 188 1.75E-56 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_0378 5a118ed194c2fd3a8f051d5fec1a3afc 96 Pfam PF00276 Ribosomal protein L23 6 90 4.0E-31 T 11-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TO73_0378 5a118ed194c2fd3a8f051d5fec1a3afc 96 SUPERFAMILY SSF54189 4 93 1.47E-31 T 11-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0378 5a118ed194c2fd3a8f051d5fec1a3afc 96 Gene3D G3DSA:3.30.70.330 1 96 3.9E-37 T 11-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TO73_0378 5a118ed194c2fd3a8f051d5fec1a3afc 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 94 21.795 T 11-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TO73_1438 88969c97e0f69b9a6b7a68575338d407 355 SUPERFAMILY SSF50331 241 354 3.4E-12 T 11-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TO73_1438 88969c97e0f69b9a6b7a68575338d407 355 Pfam PF00005 ABC transporter 22 164 1.7E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1438 88969c97e0f69b9a6b7a68575338d407 355 SUPERFAMILY SSF52540 6 243 7.4E-90 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1438 88969c97e0f69b9a6b7a68575338d407 355 Gene3D G3DSA:3.40.50.300 3 241 3.8E-78 T 11-10-2018 TO73_1438 88969c97e0f69b9a6b7a68575338d407 355 SMART SM00382 31 214 2.2E-18 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1438 88969c97e0f69b9a6b7a68575338d407 355 Pfam PF08402 TOBE domain 271 352 9.4E-9 T 11-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TO73_1438 88969c97e0f69b9a6b7a68575338d407 355 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_2124 26095b0c05f34786f0db7a5eac71b44b 407 Pfam PF07690 Major Facilitator Superfamily 29 250 5.2E-10 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_2124 26095b0c05f34786f0db7a5eac71b44b 407 Pfam PF07690 Major Facilitator Superfamily 265 397 3.6E-15 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_2124 26095b0c05f34786f0db7a5eac71b44b 407 Gene3D G3DSA:1.20.1250.20 243 402 1.6E-14 T 11-10-2018 TO73_2124 26095b0c05f34786f0db7a5eac71b44b 407 Gene3D G3DSA:1.20.1250.20 23 221 1.8E-9 T 11-10-2018 TO73_2124 26095b0c05f34786f0db7a5eac71b44b 407 SUPERFAMILY SSF103473 22 400 3.66E-31 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_1742 07cadcb8fd002551fdd47f28b75fadbd 314 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 5 287 35.461 T 11-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TO73_1742 07cadcb8fd002551fdd47f28b75fadbd 314 SUPERFAMILY SSF53335 2 286 1.98E-77 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1742 07cadcb8fd002551fdd47f28b75fadbd 314 Pfam PF01564 Spermine/spermidine synthase domain 61 231 7.2E-43 T 11-10-2018 TO73_1742 07cadcb8fd002551fdd47f28b75fadbd 314 Pfam PF17284 Spermidine synthase tetramerisation domain 5 57 1.0E-9 T 11-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TO73_1742 07cadcb8fd002551fdd47f28b75fadbd 314 Gene3D G3DSA:3.40.50.150 56 311 3.0E-92 T 11-10-2018 TO73_1742 07cadcb8fd002551fdd47f28b75fadbd 314 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 81 94 - T 11-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TO73_1742 07cadcb8fd002551fdd47f28b75fadbd 314 Gene3D G3DSA:2.30.140.10 3 54 4.9E-20 T 11-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TO73_0082 7ecadb52de5059ef22ca7441293776ab 60 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 8 36 - T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TO73_0082 7ecadb52de5059ef22ca7441293776ab 60 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 7 59 2.1E-16 T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TO73_0082 7ecadb52de5059ef22ca7441293776ab 60 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 5 59 2.5E-18 T 11-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 TO73_0082 7ecadb52de5059ef22ca7441293776ab 60 Hamap MF_00422 Protein translocase subunit SecE [secE]. 3 58 12.438 T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TO73_0082 7ecadb52de5059ef22ca7441293776ab 60 Gene3D G3DSA:1.20.5.1030 1 60 1.6E-24 T 11-10-2018 IPR038379 SecE superfamily TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 1.2E-44 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 SUPERFAMILY SSF56645 1 243 3.66E-59 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 SUPERFAMILY SSF47203 229 380 6.6E-52 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 201 2.9E-15 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 Gene3D G3DSA:1.20.140.10 240 383 3.4E-43 T 11-10-2018 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 PIRSF PIRSF016578 4 83 2.3 T 11-10-2018 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 PIRSF PIRSF016578 241 362 3.0E-9 T 11-10-2018 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 PIRSF PIRSF016578 139 194 0.087 T 11-10-2018 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 123 2.0E-21 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 Gene3D G3DSA:2.40.110.10 126 238 2.1E-26 T 11-10-2018 TO73_0904 96381fc283c449d80fe02e9c2900bc32 386 Gene3D G3DSA:1.10.540.10 1 125 2.2E-37 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TO73_1083 60e1ef1e91eecad0cbd5a122d2add466 530 Gene3D G3DSA:3.40.605.10 25 493 5.0E-142 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TO73_1083 60e1ef1e91eecad0cbd5a122d2add466 530 SUPERFAMILY SSF53720 12 501 9.16E-139 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TO73_1083 60e1ef1e91eecad0cbd5a122d2add466 530 Gene3D G3DSA:3.40.309.10 267 469 5.0E-142 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TO73_1083 60e1ef1e91eecad0cbd5a122d2add466 530 Pfam PF00171 Aldehyde dehydrogenase family 29 498 2.0E-135 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TO73_1083 60e1ef1e91eecad0cbd5a122d2add466 530 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TO73_0044 1ee84817ac0016b66a142a745720e2ea 377 ProSitePatterns PS00216 Sugar transport proteins signature 1. 250 266 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TO73_0044 1ee84817ac0016b66a142a745720e2ea 377 SUPERFAMILY SSF103473 5 367 2.09E-51 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_0044 1ee84817ac0016b66a142a745720e2ea 377 Gene3D G3DSA:1.20.1250.20 1 182 1.8E-24 T 11-10-2018 TO73_0044 1ee84817ac0016b66a142a745720e2ea 377 Pfam PF07690 Major Facilitator Superfamily 8 335 1.0E-38 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_0044 1ee84817ac0016b66a142a745720e2ea 377 Gene3D G3DSA:1.20.1250.20 195 374 1.8E-17 T 11-10-2018 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 3 145 9.2E-64 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 314 9.6E-138 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 Gene3D G3DSA:3.90.226.10 1 315 5.0E-123 T 11-10-2018 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 SUPERFAMILY SSF52096 2 313 2.56E-96 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 2 313 50.251 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 194 203 2.8E-45 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 110 128 2.8E-45 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 131 147 2.8E-45 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 166 179 2.8E-45 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 150 163 2.8E-45 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0230 358f1870de4797b9c567e7e7db3ed84f 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 85 96 2.8E-45 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_2283 b8088d2ae3889daf1787f81afeb18759 238 SUPERFAMILY SSF75217 60 235 3.56E-44 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases TO73_2283 b8088d2ae3889daf1787f81afeb18759 238 Gene3D G3DSA:3.30.1330.30 1 68 3.5E-5 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like TO73_2283 b8088d2ae3889daf1787f81afeb18759 238 SUPERFAMILY SSF55315 1 68 5.89E-13 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like TO73_2283 b8088d2ae3889daf1787f81afeb18759 238 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 2 71 2.8E-16 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TO73_2283 b8088d2ae3889daf1787f81afeb18759 238 Gene3D G3DSA:3.40.1280.10 72 235 2.0E-51 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TO73_2283 b8088d2ae3889daf1787f81afeb18759 238 SMART SM00967 2 72 1.2E-16 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TO73_2283 b8088d2ae3889daf1787f81afeb18759 238 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 231 9.9E-60 T 11-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 TO73_2283 b8088d2ae3889daf1787f81afeb18759 238 Pfam PF00588 SpoU rRNA Methylase family 89 229 2.7E-37 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TO73_1722 23ea5ed77b645efe964b0568558075e4 426 Pfam PF01551 Peptidase family M23 334 409 5.6E-13 T 11-10-2018 IPR016047 Peptidase M23 TO73_1722 23ea5ed77b645efe964b0568558075e4 426 SUPERFAMILY SSF90257 10 121 4.45E-5 T 11-10-2018 TO73_1722 23ea5ed77b645efe964b0568558075e4 426 SUPERFAMILY SSF51261 243 395 4.03E-17 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_1722 23ea5ed77b645efe964b0568558075e4 426 Gene3D G3DSA:1.20.5.340 9 130 2.1E-8 T 11-10-2018 TO73_1722 23ea5ed77b645efe964b0568558075e4 426 Gene3D G3DSA:2.70.70.10 328 426 1.8E-15 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_1990 23de13d5c042f1d3e904ec2ad6897189 359 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 12 343 26.334 T 11-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TO73_1990 23de13d5c042f1d3e904ec2ad6897189 359 SUPERFAMILY SSF55681 2 301 1.91E-52 T 11-10-2018 TO73_1990 23de13d5c042f1d3e904ec2ad6897189 359 Gene3D G3DSA:3.30.930.10 1 308 1.1E-59 T 11-10-2018 TO73_1990 23de13d5c042f1d3e904ec2ad6897189 359 PIRSF PIRSF001549 1 327 6.4E-50 T 11-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TO73_1990 23de13d5c042f1d3e904ec2ad6897189 359 Pfam PF13393 Histidyl-tRNA synthetase 5 297 2.8E-69 T 11-10-2018 TO73_1028 b3047c0d16f8d651aa15c19c79a8f945 167 Pfam PF07969 Amidohydrolase family 29 165 1.7E-7 T 11-10-2018 IPR013108 Amidohydrolase 3 TO73_1028 b3047c0d16f8d651aa15c19c79a8f945 167 Gene3D G3DSA:3.20.20.140 45 128 2.6E-5 T 11-10-2018 TO73_1028 b3047c0d16f8d651aa15c19c79a8f945 167 Gene3D G3DSA:2.30.40.10 129 157 2.6E-5 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TO73_107 fe200f8e484fb8b0f3393b1b3d53088c 232 Pfam PF01134 Glucose inhibited division protein A 5 40 3.6E-6 T 11-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TO73_107 fe200f8e484fb8b0f3393b1b3d53088c 232 Pfam PF01134 Glucose inhibited division protein A 69 166 7.2E-12 T 11-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TO73_107 fe200f8e484fb8b0f3393b1b3d53088c 232 SUPERFAMILY SSF51905 1 187 3.6E-26 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_107 fe200f8e484fb8b0f3393b1b3d53088c 232 Gene3D G3DSA:3.50.50.60 1 232 3.5E-94 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_107 fe200f8e484fb8b0f3393b1b3d53088c 232 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 117 126 8.9E-5 T 11-10-2018 TO73_107 fe200f8e484fb8b0f3393b1b3d53088c 232 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 8.9E-5 T 11-10-2018 TO73_107 fe200f8e484fb8b0f3393b1b3d53088c 232 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 225 232 8.9E-5 T 11-10-2018 TO73_0935 f801ef4b667dd2279604bc0b3d4c4a1c 298 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 281 8.1E-27 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_0267 17f3d5a3831925a9e81a99feb6a4e497 110 PRINTS PR00421 Thioredoxin family signature 22 30 7.1E-8 T 11-10-2018 TO73_0267 17f3d5a3831925a9e81a99feb6a4e497 110 PRINTS PR00421 Thioredoxin family signature 30 39 7.1E-8 T 11-10-2018 TO73_0267 17f3d5a3831925a9e81a99feb6a4e497 110 PRINTS PR00421 Thioredoxin family signature 70 81 7.1E-8 T 11-10-2018 TO73_0267 17f3d5a3831925a9e81a99feb6a4e497 110 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 2.5E-39 T 11-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TO73_0267 17f3d5a3831925a9e81a99feb6a4e497 110 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TO73_0267 17f3d5a3831925a9e81a99feb6a4e497 110 Gene3D G3DSA:3.40.30.10 2 110 3.7E-38 T 11-10-2018 TO73_0267 17f3d5a3831925a9e81a99feb6a4e497 110 SUPERFAMILY SSF52833 3 107 8.42E-41 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_0267 17f3d5a3831925a9e81a99feb6a4e497 110 Pfam PF00085 Thioredoxin 5 105 1.4E-33 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 TO73_0267 17f3d5a3831925a9e81a99feb6a4e497 110 PIRSF PIRSF000077 1 106 5.1E-42 T 11-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TO73_0443 911d74d01c8bb7a2852171b4c2081c42 84 SUPERFAMILY SSF82697 4 80 1.12E-18 T 11-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_0443 911d74d01c8bb7a2852171b4c2081c42 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 4 79 17.534 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_0443 911d74d01c8bb7a2852171b4c2081c42 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 6 78 2.0E-20 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_0443 911d74d01c8bb7a2852171b4c2081c42 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 78 2.9E-15 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_0443 911d74d01c8bb7a2852171b4c2081c42 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 12 83 4.0E-20 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TO73_0443 911d74d01c8bb7a2852171b4c2081c42 84 Gene3D G3DSA:3.30.1280.10 1 84 6.3E-29 T 11-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 346 426 1.2E-24 T 11-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 SUPERFAMILY SSF52540 135 429 3.5E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 PIRSF PIRSF006485 1 432 3.2E-151 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 426 4.9E-147 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 153 2.0E-25 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 174 335 1.3E-29 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 Hamap MF_00195 GTPase Der [der]. 1 429 34.668 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 Gene3D G3DSA:3.30.300.20 346 429 3.1E-23 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 SUPERFAMILY SSF52540 3 161 1.57E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 Pfam PF01926 50S ribosome-binding GTPase 3 117 3.3E-27 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 Pfam PF01926 50S ribosome-binding GTPase 176 290 4.3E-26 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 4.5E-6 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 88 4.5E-6 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 4.5E-6 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 Gene3D G3DSA:3.40.50.300 171 342 5.0E-47 T 11-10-2018 TO73_0546 859778920aff0a7de5104d3b19f8c6a7 432 Gene3D G3DSA:3.40.50.300 1 161 7.7E-48 T 11-10-2018 TO73_1470 8fe4876a84f35e21f9cd87b036c44ad5 344 Gene3D G3DSA:3.20.20.70 77 333 1.4E-94 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1470 8fe4876a84f35e21f9cd87b036c44ad5 344 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 72 328 1.3E-115 T 11-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TO73_1470 8fe4876a84f35e21f9cd87b036c44ad5 344 SUPERFAMILY SSF51569 1 336 7.88E-109 T 11-10-2018 TO73_1470 8fe4876a84f35e21f9cd87b036c44ad5 344 Gene3D G3DSA:3.30.70.1140 1 76 6.3E-20 T 11-10-2018 TO73_1470 8fe4876a84f35e21f9cd87b036c44ad5 344 Pfam PF00793 DAHP synthetase I family 91 325 7.8E-72 T 11-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TO73_1530 3d9d0e8467a519c9aca6a42599eaa619 328 Gene3D G3DSA:2.40.370.10 29 197 1.6E-15 T 11-10-2018 IPR023374 AttH-like domain superfamily TO73_1530 3d9d0e8467a519c9aca6a42599eaa619 328 Pfam PF07143 CrtC N-terminal lipocalin domain 40 194 4.5E-16 T 11-10-2018 IPR010791 AttH domain TO73_1530 3d9d0e8467a519c9aca6a42599eaa619 328 SUPERFAMILY SSF159245 25 321 2.88E-50 T 11-10-2018 TO73_1530 3d9d0e8467a519c9aca6a42599eaa619 328 Gene3D G3DSA:2.40.370.10 200 323 5.5E-25 T 11-10-2018 IPR023374 AttH-like domain superfamily TO73_1530 3d9d0e8467a519c9aca6a42599eaa619 328 Pfam PF17186 Lipocalin-like domain 201 310 3.1E-22 T 11-10-2018 TO73_1152 600cdde5f16e959aa0d50fcfe32e9d3f 352 SUPERFAMILY SSF53383 3 346 1.47E-76 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1152 600cdde5f16e959aa0d50fcfe32e9d3f 352 Gene3D G3DSA:3.40.640.10 13 249 3.7E-116 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1152 600cdde5f16e959aa0d50fcfe32e9d3f 352 Pfam PF00266 Aminotransferase class-V 21 316 1.1E-22 T 11-10-2018 IPR000192 Aminotransferase class V domain TO73_1152 600cdde5f16e959aa0d50fcfe32e9d3f 352 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 176 196 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TO73_1152 600cdde5f16e959aa0d50fcfe32e9d3f 352 PIRSF PIRSF000524 1 350 4.4E-82 T 11-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TO73_1152 600cdde5f16e959aa0d50fcfe32e9d3f 352 Gene3D G3DSA:3.90.1150.10 4 331 3.7E-116 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_0290 276784c45f654b036f82d4ddd2660f3f 100 SUPERFAMILY SSF50022 2 98 1.83E-26 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TO73_0290 276784c45f654b036f82d4ddd2660f3f 100 Gene3D G3DSA:2.102.10.10 1 100 5.9E-28 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TO73_0290 276784c45f654b036f82d4ddd2660f3f 100 Pfam PF00355 Rieske [2Fe-2S] domain 2 88 9.2E-16 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TO73_2290 3da948c46c3e2def8f0cfac3f52527b9 126 SUPERFAMILY SSF55811 4 124 1.18E-29 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TO73_2290 3da948c46c3e2def8f0cfac3f52527b9 126 ProSitePatterns PS00893 Nudix box signature. 31 52 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TO73_2290 3da948c46c3e2def8f0cfac3f52527b9 126 Pfam PF00293 NUDIX domain 4 109 3.5E-19 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TO73_2290 3da948c46c3e2def8f0cfac3f52527b9 126 Gene3D G3DSA:3.90.79.10 3 124 4.5E-40 T 11-10-2018 TO73_2290 3da948c46c3e2def8f0cfac3f52527b9 126 PRINTS PR00502 NUDIX hydrolase family signature 40 55 8.4E-8 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_2290 3da948c46c3e2def8f0cfac3f52527b9 126 PRINTS PR00502 NUDIX hydrolase family signature 26 40 8.4E-8 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_0241 d10bcedd1096ac6599c178183034dc2f 216 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 210 1.7E-60 T 11-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TO73_0241 d10bcedd1096ac6599c178183034dc2f 216 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 210 3.6E-50 T 11-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TO73_0241 d10bcedd1096ac6599c178183034dc2f 216 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 5 211 38.912 T 11-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TO73_0241 d10bcedd1096ac6599c178183034dc2f 216 Gene3D G3DSA:3.90.550.10 4 216 1.5E-68 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0241 d10bcedd1096ac6599c178183034dc2f 216 SUPERFAMILY SSF53448 6 210 2.53E-45 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0241 d10bcedd1096ac6599c178183034dc2f 216 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 89 96 - T 11-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TO73_2744 488ffa0f3a6c9163b33cb12f8db14756 321 Gene3D G3DSA:3.40.50.300 49 317 4.2E-45 T 11-10-2018 TO73_2744 488ffa0f3a6c9163b33cb12f8db14756 321 Pfam PF13614 AAA domain 58 222 4.1E-29 T 11-10-2018 IPR025669 AAA domain TO73_2744 488ffa0f3a6c9163b33cb12f8db14756 321 SUPERFAMILY SSF52540 56 314 9.96E-34 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1741 b91d051902a9abe9db804cab6a19970f 200 SUPERFAMILY SSF52833 27 195 1.51E-41 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1741 b91d051902a9abe9db804cab6a19970f 200 Pfam PF13462 Thioredoxin 28 196 1.9E-35 T 11-10-2018 IPR012336 Thioredoxin-like fold TO73_1741 b91d051902a9abe9db804cab6a19970f 200 Gene3D G3DSA:3.40.30.10 18 200 1.2E-50 T 11-10-2018 TO73_0567 f6df50f8f06d3aa4776fd924a72076bf 252 Gene3D G3DSA:3.30.420.40 3 243 1.9E-75 T 11-10-2018 TO73_0567 f6df50f8f06d3aa4776fd924a72076bf 252 Pfam PF03309 Type III pantothenate kinase 2 205 3.1E-60 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TO73_0567 f6df50f8f06d3aa4776fd924a72076bf 252 Gene3D G3DSA:3.30.420.490 123 236 1.9E-75 T 11-10-2018 TO73_0567 f6df50f8f06d3aa4776fd924a72076bf 252 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 252 31.508 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TO73_0567 f6df50f8f06d3aa4776fd924a72076bf 252 SUPERFAMILY SSF53067 123 247 1.0E-33 T 11-10-2018 TO73_0567 f6df50f8f06d3aa4776fd924a72076bf 252 SUPERFAMILY SSF53067 1 115 5.5E-28 T 11-10-2018 TO73_0567 f6df50f8f06d3aa4776fd924a72076bf 252 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 246 2.5E-57 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TO73_0158 3ee9e8991b2a29b203868feac7ce773c 675 SUPERFAMILY SSF49478 130 190 1.18E-11 T 11-10-2018 TO73_0158 3ee9e8991b2a29b203868feac7ce773c 675 Gene3D G3DSA:2.60.40.10 131 239 9.0E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0158 3ee9e8991b2a29b203868feac7ce773c 675 Gene3D G3DSA:2.60.40.10 382 486 8.1E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0158 3ee9e8991b2a29b203868feac7ce773c 675 Pfam PF13620 Carboxypeptidase regulatory-like domain 130 200 6.7E-15 T 11-10-2018 TO73_0997 3e29956b8ef1c860b87d0e89ff765aa1 582 SUPERFAMILY SSF52540 333 578 1.84E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0997 3e29956b8ef1c860b87d0e89ff765aa1 582 Pfam PF02653 Branched-chain amino acid transport system / permease component 22 293 2.6E-39 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_0997 3e29956b8ef1c860b87d0e89ff765aa1 582 Pfam PF00005 ABC transporter 351 507 2.6E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0997 3e29956b8ef1c860b87d0e89ff765aa1 582 Gene3D G3DSA:3.40.50.300 330 580 1.6E-62 T 11-10-2018 TO73_0997 3e29956b8ef1c860b87d0e89ff765aa1 582 SMART SM00382 359 557 5.1E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0997 3e29956b8ef1c860b87d0e89ff765aa1 582 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 557 579 4.4E-10 T 11-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TO73_2050 1b1a593f29b53a3b590236218cdce39a 130 SUPERFAMILY SSF54593 1 129 4.4E-29 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_2050 1b1a593f29b53a3b590236218cdce39a 130 Gene3D G3DSA:3.10.180.10 1 129 9.3E-35 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_2050 1b1a593f29b53a3b590236218cdce39a 130 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 2 129 1.5E-35 T 11-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 TO73_2050 1b1a593f29b53a3b590236218cdce39a 130 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 114 4.3E-23 T 11-10-2018 TO73_1350 964e701f2bc4d340a03c2d14453802e8 156 Pfam PF06695 Putative small multi-drug export protein 19 139 3.2E-36 T 11-10-2018 IPR009577 Putative small multi-drug export TO73_2711 87fabd03e38a302ef495c412a5f2d53c 319 SUPERFAMILY SSF52540 124 245 3.1E-12 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2711 87fabd03e38a302ef495c412a5f2d53c 319 SMART SM00382 125 280 1.7E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2711 87fabd03e38a302ef495c412a5f2d53c 319 Gene3D G3DSA:3.40.50.300 105 279 6.8E-20 T 11-10-2018 TO73_0108 249f278d931e4866ef14b8dfb1bd218a 90 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 5 72 4.0E-16 T 11-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TO73_0108 249f278d931e4866ef14b8dfb1bd218a 90 Gene3D G3DSA:3.30.70.240 1 90 3.7E-32 T 11-10-2018 TO73_0108 249f278d931e4866ef14b8dfb1bd218a 90 SUPERFAMILY SSF143430 5 72 2.09E-20 T 11-10-2018 TO73_0108 249f278d931e4866ef14b8dfb1bd218a 90 Pfam PF09827 CRISPR associated protein Cas2 5 70 7.1E-18 T 11-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 TO73_0108 249f278d931e4866ef14b8dfb1bd218a 90 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 4 88 15.702 T 11-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TO73_1979 95d326c3b5efc96d1cfebc8e12c54633 313 Pfam PF03308 ArgK protein 24 280 9.0E-98 T 11-10-2018 TO73_1979 95d326c3b5efc96d1cfebc8e12c54633 313 SUPERFAMILY SSF52540 9 294 3.9E-78 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1979 95d326c3b5efc96d1cfebc8e12c54633 313 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 19 308 3.7E-99 T 11-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TO73_1979 95d326c3b5efc96d1cfebc8e12c54633 313 Gene3D G3DSA:1.20.5.170 2 45 5.4E-7 T 11-10-2018 TO73_1979 95d326c3b5efc96d1cfebc8e12c54633 313 Gene3D G3DSA:3.40.50.300 46 255 7.0E-84 T 11-10-2018 TO73_0529 c77945852a039984e1f834aa52d016b5 178 SUPERFAMILY SSF52833 32 176 1.49E-37 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_0529 c77945852a039984e1f834aa52d016b5 178 Pfam PF00578 AhpC/TSA family 37 157 6.2E-20 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TO73_0529 c77945852a039984e1f834aa52d016b5 178 Gene3D G3DSA:3.40.30.10 20 177 1.4E-35 T 11-10-2018 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 147 154 - T 11-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 Gene3D G3DSA:3.40.50.720 2 323 9.7E-158 T 11-10-2018 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 SMART SM00846 1 149 7.3E-93 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 SUPERFAMILY SSF51735 1 165 7.07E-67 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 Gene3D G3DSA:3.30.360.10 148 311 9.7E-158 T 11-10-2018 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 154 309 3.8E-66 T 11-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 226 243 4.9E-38 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 170 186 4.9E-38 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 143 161 4.9E-38 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 106 119 4.9E-38 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 266 281 4.9E-38 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 PIRSF PIRSF000149 1 330 2.9E-127 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 2 321 1.0E-133 T 11-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1 99 9.1E-36 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_1101 54e1d24aa9fe315ebba65225dd4913c2 331 SUPERFAMILY SSF55347 149 310 3.27E-67 T 11-10-2018 TO73_2116 a5774bf6b07c0d94981f4aa6da1535b9 178 Gene3D G3DSA:2.30.110.10 1 178 6.4E-70 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TO73_2116 a5774bf6b07c0d94981f4aa6da1535b9 178 SMART SM00903 14 164 2.7E-20 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TO73_2116 a5774bf6b07c0d94981f4aa6da1535b9 178 SUPERFAMILY SSF50475 10 170 5.89E-38 T 11-10-2018 TO73_2116 a5774bf6b07c0d94981f4aa6da1535b9 178 Pfam PF01613 Flavin reductase like domain 22 165 6.0E-24 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TO73_1891 703f36d54993972f476f7e617ecc6bf9 222 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 199 4.1E-77 T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TO73_1891 703f36d54993972f476f7e617ecc6bf9 222 PIRSF PIRSF001461 1 222 5.1E-87 T 11-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TO73_1891 703f36d54993972f476f7e617ecc6bf9 222 Gene3D G3DSA:3.20.20.70 1 218 9.1E-80 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1891 703f36d54993972f476f7e617ecc6bf9 222 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 212 1.3E-85 T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TO73_1891 703f36d54993972f476f7e617ecc6bf9 222 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TO73_1891 703f36d54993972f476f7e617ecc6bf9 222 SUPERFAMILY SSF51366 3 215 8.24E-70 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TO73_0131 86f2360a91a1c44a500c37a4d8101088 275 SUPERFAMILY SSF51735 3 245 8.05E-57 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0131 86f2360a91a1c44a500c37a4d8101088 275 Pfam PF00106 short chain dehydrogenase 4 182 6.6E-36 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0131 86f2360a91a1c44a500c37a4d8101088 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TO73_0131 86f2360a91a1c44a500c37a4d8101088 275 Gene3D G3DSA:3.40.50.720 3 258 1.7E-65 T 11-10-2018 TO73_0131 86f2360a91a1c44a500c37a4d8101088 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 3.1E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0131 86f2360a91a1c44a500c37a4d8101088 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 3.1E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0131 86f2360a91a1c44a500c37a4d8101088 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 3.1E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0131 86f2360a91a1c44a500c37a4d8101088 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 3.1E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0131 86f2360a91a1c44a500c37a4d8101088 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.1E-18 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1053 e7b55440f08c64a0e591e6b303e263ac 412 Gene3D G3DSA:3.40.640.10 1 277 1.5E-91 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1053 e7b55440f08c64a0e591e6b303e263ac 412 Gene3D G3DSA:3.90.1150.10 278 412 2.7E-43 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1053 e7b55440f08c64a0e591e6b303e263ac 412 PIRSF PIRSF001434 1 412 5.9E-120 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TO73_1053 e7b55440f08c64a0e591e6b303e263ac 412 SUPERFAMILY SSF53383 1 410 2.39E-97 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1053 e7b55440f08c64a0e591e6b303e263ac 412 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 410 4.1E-104 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TO73_0151 d8726ca2eaca13f479c46df08631bc05 164 Pfam PF06778 Chlorite dismutase 25 93 2.7E-7 T 11-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase TO73_0151 d8726ca2eaca13f479c46df08631bc05 164 Gene3D G3DSA:3.30.70.1030 2 96 8.7E-9 T 11-10-2018 TO73_0151 d8726ca2eaca13f479c46df08631bc05 164 SUPERFAMILY SSF54909 4 93 1.58E-7 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel TO73_0659 cc3294085f3e9992e0c5eb08fc2a177c 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 330 3.1E-44 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_2069 020235b1c6acfe18213d5ce855167855 177 Gene3D G3DSA:3.50.50.60 1 170 2.3E-66 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_2069 020235b1c6acfe18213d5ce855167855 177 Pfam PF00890 FAD binding domain 1 32 1.2E-6 T 11-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_2069 020235b1c6acfe18213d5ce855167855 177 SUPERFAMILY SSF51905 1 168 7.56E-30 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 Gene3D G3DSA:1.10.240.10 189 295 1.5E-133 T 11-10-2018 TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 Gene3D G3DSA:3.40.50.620 3 327 1.5E-133 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 328 38.675 T 11-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 195 205 3.0E-25 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 143 164 3.0E-25 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 3.0E-25 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 68 87 3.0E-25 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 SUPERFAMILY SSF52374 1 327 1.49E-89 T 11-10-2018 TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 Pfam PF00579 tRNA synthetases class I (W and Y) 3 277 4.2E-70 T 11-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1424 e9a8cbf874bae32f9ab239cfcf17be37 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 327 5.4E-93 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TO73_0561 81e617104d196e6a057a20e551316e09 473 Pfam PF01966 HD domain 261 384 4.1E-22 T 11-10-2018 IPR006674 HD domain TO73_0561 81e617104d196e6a057a20e551316e09 473 Gene3D G3DSA:1.10.3210.10 233 427 2.1E-69 T 11-10-2018 TO73_0561 81e617104d196e6a057a20e551316e09 473 TIGRFAM TIGR00277 HDIG: HDIG domain 256 352 4.1E-7 T 11-10-2018 IPR006675 HDIG domain TO73_0561 81e617104d196e6a057a20e551316e09 473 SUPERFAMILY SSF109604 245 424 5.5E-40 T 11-10-2018 TO73_0561 81e617104d196e6a057a20e551316e09 473 SMART SM00471 254 393 2.9E-13 T 11-10-2018 IPR003607 HD/PDEase domain TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 SUPERFAMILY SSF52402 1 203 3.75E-53 T 11-10-2018 TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 11-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 Gene3D G3DSA:3.40.50.620 3 170 8.0E-165 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 395 54.442 T 11-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 114 125 - T 11-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 Gene3D G3DSA:1.20.5.470 370 400 1.6E-17 T 11-10-2018 TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 Gene3D G3DSA:3.90.1260.10 61 351 8.0E-165 T 11-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 389 2.8E-157 T 11-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 Pfam PF00764 Arginosuccinate synthase 4 389 3.8E-165 T 11-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TO73_0159 9a053c2cc7dc6e72478f9d9a54aad61e 400 SUPERFAMILY SSF69864 169 394 1.83E-96 T 11-10-2018 TO73_0511 30422120f128938eafc4cc05083d7398 316 Pfam PF00005 ABC transporter 17 156 9.7E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0511 30422120f128938eafc4cc05083d7398 316 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0511 30422120f128938eafc4cc05083d7398 316 SMART SM00382 23 214 2.5E-19 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0511 30422120f128938eafc4cc05083d7398 316 SUPERFAMILY SSF52540 6 235 5.99E-79 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0511 30422120f128938eafc4cc05083d7398 316 Gene3D G3DSA:3.40.50.300 13 255 2.6E-71 T 11-10-2018 TO73_1102 d068cd6d3c66de063d8c8aeb9858663e 202 PIRSF PIRSF016661 11 202 1.8E-43 T 11-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TO73_1102 d068cd6d3c66de063d8c8aeb9858663e 202 Gene3D G3DSA:1.10.1760.20 14 198 1.4E-52 T 11-10-2018 TO73_1102 d068cd6d3c66de063d8c8aeb9858663e 202 Pfam PF02632 BioY family 48 197 1.6E-42 T 11-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TO73_0875 d804812e9339f47b096060eecbe2b0cc 219 PIRSF PIRSF000857 1 218 1.6E-72 T 11-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 TO73_0875 d804812e9339f47b096060eecbe2b0cc 219 Gene3D G3DSA:3.40.50.620 1 218 4.9E-67 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0875 d804812e9339f47b096060eecbe2b0cc 219 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 19 213 8.0E-62 T 11-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 TO73_0875 d804812e9339f47b096060eecbe2b0cc 219 SUPERFAMILY SSF52402 2 178 2.55E-50 T 11-10-2018 TO73_0875 d804812e9339f47b096060eecbe2b0cc 219 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 18 189 1.4E-47 T 11-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TO73_0569 6cd30278fdb7a835079990af91e552c9 364 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 138 354 7.0E-44 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TO73_0569 6cd30278fdb7a835079990af91e552c9 364 SMART SM00646 201 354 1.8E-35 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TO73_0569 6cd30278fdb7a835079990af91e552c9 364 Gene3D G3DSA:3.40.630.40 124 363 2.1E-55 T 11-10-2018 TO73_0569 6cd30278fdb7a835079990af91e552c9 364 SUPERFAMILY SSF53187 136 357 7.22E-47 T 11-10-2018 TO73_0363 d64a199688534cb09eb9f2e75f8578e7 334 SMART SM00729 21 225 7.7E-15 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_0363 d64a199688534cb09eb9f2e75f8578e7 334 Pfam PF04055 Radical SAM superfamily 25 182 4.4E-31 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_0363 d64a199688534cb09eb9f2e75f8578e7 334 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 12 334 1.2E-102 T 11-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_0363 d64a199688534cb09eb9f2e75f8578e7 334 Pfam PF13353 4Fe-4S single cluster domain 29 130 4.4E-6 T 11-10-2018 TO73_0363 d64a199688534cb09eb9f2e75f8578e7 334 Pfam PF06463 Molybdenum Cofactor Synthesis C 192 316 5.5E-27 T 11-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_0363 d64a199688534cb09eb9f2e75f8578e7 334 Gene3D G3DSA:3.20.20.70 9 334 1.2E-81 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0363 d64a199688534cb09eb9f2e75f8578e7 334 SUPERFAMILY SSF102114 12 285 9.29E-69 T 11-10-2018 TO73_1932 c4281d0ddce21c87b4550324c993f687 260 Gene3D G3DSA:1.20.120.1760 8 153 1.1E-21 T 11-10-2018 TO73_1932 c4281d0ddce21c87b4550324c993f687 260 Pfam PF01066 CDP-alcohol phosphatidyltransferase 37 97 1.1E-7 T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TO73_1932 c4281d0ddce21c87b4550324c993f687 260 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 77 99 - T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 11-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 Gene3D G3DSA:3.20.20.140 54 365 3.3E-125 T 11-10-2018 TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 19 423 2.6E-111 T 11-10-2018 TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 SUPERFAMILY SSF51338 2 423 1.54E-18 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 Pfam PF01979 Amidohydrolase family 47 421 1.1E-21 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 ProSitePatterns PS00482 Dihydroorotase signature 1. 53 61 - T 11-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 SUPERFAMILY SSF51556 50 367 4.93E-94 T 11-10-2018 IPR032466 Metal-dependent hydrolase TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 Gene3D G3DSA:2.30.40.10 1 53 2.8E-11 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 Gene3D G3DSA:2.30.40.10 366 425 9.0E-20 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TO73_1492 ec76402ca21ad47e3409fa62d3b28fa3 425 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 424 41.835 T 11-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TO73_2022 8549480d8449db86cf5340775184d164 181 SUPERFAMILY SSF53271 12 180 3.67E-49 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_2022 8549480d8449db86cf5340775184d164 181 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 12 176 3.1E-62 T 11-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 TO73_2022 8549480d8449db86cf5340775184d164 181 Pfam PF00156 Phosphoribosyl transferase domain 17 142 1.4E-22 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TO73_2022 8549480d8449db86cf5340775184d164 181 Gene3D G3DSA:3.40.50.2020 1 181 9.6E-61 T 11-10-2018 TO73_2093 8a0a271a09f60508b8caa466d9cc8c2a 226 SUPERFAMILY SSF53474 4 226 6.51E-27 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_2093 8a0a271a09f60508b8caa466d9cc8c2a 226 Gene3D G3DSA:3.40.50.1820 1 226 3.1E-56 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0411 a2e078337876d344d1d7491740e048a8 263 SUPERFAMILY SSF110997 194 260 2.62E-11 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TO73_0411 a2e078337876d344d1d7491740e048a8 263 Gene3D G3DSA:3.30.70.1070 196 262 1.1E-10 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TO73_0411 a2e078337876d344d1d7491740e048a8 263 Gene3D G3DSA:3.30.70.1070 120 187 6.5E-15 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TO73_0411 a2e078337876d344d1d7491740e048a8 263 Pfam PF05036 Sporulation related domain 119 184 3.9E-17 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 TO73_0411 a2e078337876d344d1d7491740e048a8 263 Pfam PF05036 Sporulation related domain 196 260 9.8E-11 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 TO73_0411 a2e078337876d344d1d7491740e048a8 263 SUPERFAMILY SSF110997 118 183 3.14E-16 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TO73_0866 b7d94365628423dbb75c54058141bf68 329 Gene3D G3DSA:3.40.50.10210 37 309 2.1E-133 T 11-10-2018 TO73_0866 b7d94365628423dbb75c54058141bf68 329 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1 327 33.232 T 11-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TO73_0866 b7d94365628423dbb75c54058141bf68 329 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2 325 1.4E-125 T 11-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TO73_0866 b7d94365628423dbb75c54058141bf68 329 SUPERFAMILY SSF52733 2 327 1.18E-112 T 11-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TO73_0866 b7d94365628423dbb75c54058141bf68 329 Gene3D G3DSA:1.10.1610.10 5 325 2.1E-133 T 11-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TO73_0866 b7d94365628423dbb75c54058141bf68 329 Pfam PF02277 Phosphoribosyltransferase 2 325 7.6E-123 T 11-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 Gene3D G3DSA:3.10.20.600 240 334 8.7E-37 T 11-10-2018 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 57 226 2.7E-52 T 11-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 18 421 8.7E-175 T 11-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 SUPERFAMILY SSF142019 15 247 5.49E-92 T 11-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 Gene3D G3DSA:3.40.50.11540 62 239 1.5E-85 T 11-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 350 361 - T 11-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 339 421 2.8E-25 T 11-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 Gene3D G3DSA:1.20.1440.230 335 437 2.1E-35 T 11-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 SUPERFAMILY SSF142984 249 331 1.07E-24 T 11-10-2018 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 Pfam PF10531 SLBB domain 251 297 7.9E-13 T 11-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 SMART SM00928 337 383 7.6E-20 T 11-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 175 190 - T 11-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1581 70975b73266b6dd3cea21d5de0fae1d5 437 SUPERFAMILY SSF140490 334 429 9.29E-32 T 11-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_2604 b170c80a898081b389717ecdfdbb45ec 179 Pfam PF00196 Bacterial regulatory proteins, luxR family 110 165 5.0E-16 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_2604 b170c80a898081b389717ecdfdbb45ec 179 ProSitePatterns PS00622 LuxR-type HTH domain signature. 126 153 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_2604 b170c80a898081b389717ecdfdbb45ec 179 SUPERFAMILY SSF46894 103 168 3.74E-18 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TO73_2604 b170c80a898081b389717ecdfdbb45ec 179 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 126 142 1.4E-9 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_2604 b170c80a898081b389717ecdfdbb45ec 179 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 112 126 1.4E-9 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_2604 b170c80a898081b389717ecdfdbb45ec 179 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 154 1.4E-9 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_2604 b170c80a898081b389717ecdfdbb45ec 179 Gene3D G3DSA:1.10.10.10 108 170 1.1E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2604 b170c80a898081b389717ecdfdbb45ec 179 SMART SM00421 109 166 1.0E-18 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_2402 5126f51beee58ecd011df3f6c8a84b67 430 Pfam PF02096 60Kd inner membrane protein 249 423 1.2E-55 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TO73_2402 5126f51beee58ecd011df3f6c8a84b67 430 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 1 425 14.812 T 11-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 TO73_2402 5126f51beee58ecd011df3f6c8a84b67 430 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 248 423 3.7E-59 T 11-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0225 87eb357b0ea5a95217d46a1be70a70e6 172 Pfam PF05685 Putative restriction endonuclease 10 170 1.4E-33 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_0225 87eb357b0ea5a95217d46a1be70a70e6 172 SUPERFAMILY SSF52980 9 158 2.84E-17 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_0225 87eb357b0ea5a95217d46a1be70a70e6 172 Gene3D G3DSA:3.90.1570.10 2 163 5.5E-12 T 11-10-2018 TO73_2347 31c3874dcd1c7e63bb523b05a1e0c757 300 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 2 71 1.4E-6 T 11-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 TO73_2347 31c3874dcd1c7e63bb523b05a1e0c757 300 SUPERFAMILY SSF55781 68 291 1.55E-16 T 11-10-2018 TO73_2347 31c3874dcd1c7e63bb523b05a1e0c757 300 Gene3D G3DSA:1.10.10.10 1 79 1.7E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2347 31c3874dcd1c7e63bb523b05a1e0c757 300 PIRSF PIRSF005485 183 297 0.041 T 11-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 TO73_2347 31c3874dcd1c7e63bb523b05a1e0c757 300 PIRSF PIRSF005485 1 180 6.7E-30 T 11-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 TO73_2347 31c3874dcd1c7e63bb523b05a1e0c757 300 SUPERFAMILY SSF46785 2 79 7.87E-18 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_2347 31c3874dcd1c7e63bb523b05a1e0c757 300 Pfam PF01628 HrcA protein C terminal domain 104 282 1.9E-10 T 11-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 TO73_0666 08321d2b8c4826a12ed468a24d719f07 173 Pfam PF02620 Uncharacterized ACR, COG1399 55 169 8.0E-27 T 11-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 Pfam PF00027 Cyclic nucleotide-binding domain 2 74 5.8E-14 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 SUPERFAMILY SSF51206 2 98 2.09E-19 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 Pfam PF13545 Crp-like helix-turn-helix domain 115 186 1.6E-16 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 SMART SM00100 2 102 0.0023 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 SMART SM00419 132 180 1.9E-9 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 Gene3D G3DSA:1.10.10.10 111 195 7.8E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 SUPERFAMILY SSF46785 112 189 5.36E-17 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 154 169 2.5E-5 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 138 154 2.5E-5 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_1246 2318d3a8fd95d363ce68be9486b02567 195 Gene3D G3DSA:2.60.120.10 1 110 8.9E-25 T 11-10-2018 IPR014710 RmlC-like jelly roll fold TO73_1204 39f847bfc544aa2c96ca9fcb0ad0366e 649 Pfam PF00665 Integrase core domain 241 359 3.0E-16 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 TO73_1204 39f847bfc544aa2c96ca9fcb0ad0366e 649 Gene3D G3DSA:3.30.420.10 220 451 5.9E-21 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_1204 39f847bfc544aa2c96ca9fcb0ad0366e 649 SUPERFAMILY SSF53098 229 383 1.77E-19 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_0759 80b2224e33b9fc308b04f283a7219379 47 Gene3D G3DSA:3.40.50.720 1 47 1.4E-9 T 11-10-2018 TO73_0759 80b2224e33b9fc308b04f283a7219379 47 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 40 1.5E-4 T 11-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 TO73_0759 80b2224e33b9fc308b04f283a7219379 47 SUPERFAMILY SSF51735 1 41 3.85E-8 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_2316 12e2e6f082939c6feacac252a0be40eb 304 Pfam PF02911 Formyl transferase, C-terminal domain 201 295 6.3E-29 T 11-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TO73_2316 12e2e6f082939c6feacac252a0be40eb 304 SUPERFAMILY SSF53328 1 202 1.24E-56 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TO73_2316 12e2e6f082939c6feacac252a0be40eb 304 Gene3D G3DSA:3.40.50.170 1 202 2.8E-67 T 11-10-2018 TO73_2316 12e2e6f082939c6feacac252a0be40eb 304 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 298 33.042 T 11-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 TO73_2316 12e2e6f082939c6feacac252a0be40eb 304 SUPERFAMILY SSF50486 201 303 6.28E-30 T 11-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 TO73_2316 12e2e6f082939c6feacac252a0be40eb 304 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 295 2.4E-74 T 11-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 TO73_2316 12e2e6f082939c6feacac252a0be40eb 304 Gene3D G3DSA:3.10.25.10 203 303 4.8E-26 T 11-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TO73_2316 12e2e6f082939c6feacac252a0be40eb 304 Pfam PF00551 Formyl transferase 1 180 7.9E-45 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TO73_2745 99e889b64efef5d6f772402ade794688 318 Pfam PF00589 Phage integrase family 149 312 2.9E-6 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TO73_2745 99e889b64efef5d6f772402ade794688 318 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 57 126 1.7E-5 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TO73_2745 99e889b64efef5d6f772402ade794688 318 SUPERFAMILY SSF56349 148 309 9.42E-16 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TO73_2745 99e889b64efef5d6f772402ade794688 318 Gene3D G3DSA:1.10.443.10 141 315 5.1E-10 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TO73_1709 99feecc566fef50d112f6efb36414314 319 SUPERFAMILY SSF53800 3 313 1.64E-70 T 11-10-2018 TO73_1709 99feecc566fef50d112f6efb36414314 319 Gene3D G3DSA:3.40.50.1400 158 296 4.3E-91 T 11-10-2018 TO73_1709 99feecc566fef50d112f6efb36414314 319 Pfam PF00762 Ferrochelatase 3 313 6.5E-73 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TO73_1709 99feecc566fef50d112f6efb36414314 319 Gene3D G3DSA:3.40.50.1400 3 311 4.3E-91 T 11-10-2018 TO73_1709 99feecc566fef50d112f6efb36414314 319 Hamap MF_00323 Ferrochelatase [hemH]. 1 315 26.991 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TO73_1709 99feecc566fef50d112f6efb36414314 319 TIGRFAM TIGR00109 hemH: ferrochelatase 2 312 4.0E-60 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TO73_2146 f60510d103b6ac7661dd365919961120 139 Gene3D G3DSA:2.60.40.1890 23 139 5.1E-38 T 11-10-2018 IPR036182 Copper chaperone PCuAC superfamily TO73_2146 f60510d103b6ac7661dd365919961120 139 Pfam PF04314 Copper chaperone PCu(A)C 20 132 4.4E-33 T 11-10-2018 IPR007410 Copper chaperone PCuAC TO73_2146 f60510d103b6ac7661dd365919961120 139 SUPERFAMILY SSF110087 7 138 9.81E-40 T 11-10-2018 IPR036182 Copper chaperone PCuAC superfamily TO73_1521 d2e16bbbf67888d135e85325a27b7972 252 SUPERFAMILY SSF51366 3 250 2.2E-80 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TO73_1521 d2e16bbbf67888d135e85325a27b7972 252 Gene3D G3DSA:3.20.20.70 1 252 3.2E-106 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1521 d2e16bbbf67888d135e85325a27b7972 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 250 48.488 T 11-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TO73_1521 d2e16bbbf67888d135e85325a27b7972 252 Pfam PF00977 Histidine biosynthesis protein 6 233 2.7E-85 T 11-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TO73_1521 d2e16bbbf67888d135e85325a27b7972 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 250 1.0E-107 T 11-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TO73_2180 95f551b767b8eb0de584b892e930db5a 157 Pfam PF14326 Domain of unknown function (DUF4384) 47 117 3.8E-7 T 11-10-2018 IPR025493 Domain of unknown function DUF4384 TO73_1040 60cd2d2f4874658040dd990403617a60 358 Gene3D G3DSA:3.40.190.170 31 335 1.7E-123 T 11-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TO73_1040 60cd2d2f4874658040dd990403617a60 358 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 321 4.3E-54 T 11-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TO73_1040 60cd2d2f4874658040dd990403617a60 358 Gene3D G3DSA:3.40.190.10 151 321 1.7E-123 T 11-10-2018 TO73_1040 60cd2d2f4874658040dd990403617a60 358 PIRSF PIRSF039026 1 354 7.4E-123 T 11-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TO73_0784 0bbdfe56098d13353ec0ae89510f8510 324 Pfam PF00483 Nucleotidyl transferase 5 253 8.4E-39 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TO73_0784 0bbdfe56098d13353ec0ae89510f8510 324 SUPERFAMILY SSF159283 257 320 4.32E-11 T 11-10-2018 TO73_0784 0bbdfe56098d13353ec0ae89510f8510 324 Gene3D G3DSA:3.90.550.10 4 322 3.0E-96 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0784 0bbdfe56098d13353ec0ae89510f8510 324 SUPERFAMILY SSF53448 4 252 1.13E-56 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0046 972ca397df6904de06597e83ea83e0e4 143 Gene3D G3DSA:3.10.580.10 1 141 4.8E-48 T 11-10-2018 TO73_0046 972ca397df6904de06597e83ea83e0e4 143 Pfam PF00571 CBS domain 15 60 5.5E-9 T 11-10-2018 IPR000644 CBS domain TO73_0046 972ca397df6904de06597e83ea83e0e4 143 Pfam PF00571 CBS domain 71 124 1.5E-17 T 11-10-2018 IPR000644 CBS domain TO73_0046 972ca397df6904de06597e83ea83e0e4 143 SMART SM00116 13 60 1.3E-7 T 11-10-2018 IPR000644 CBS domain TO73_0046 972ca397df6904de06597e83ea83e0e4 143 SMART SM00116 78 125 2.3E-14 T 11-10-2018 IPR000644 CBS domain TO73_0046 972ca397df6904de06597e83ea83e0e4 143 SUPERFAMILY SSF54631 1 139 4.17E-37 T 11-10-2018 TO73_2181 1b23cd7336a544f0de1fe0d266123080 200 Gene3D G3DSA:3.30.420.10 8 198 2.9E-65 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_2181 1b23cd7336a544f0de1fe0d266123080 200 SUPERFAMILY SSF53098 13 194 4.55E-59 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2181 1b23cd7336a544f0de1fe0d266123080 200 Pfam PF01351 Ribonuclease HII 16 189 7.7E-31 T 11-10-2018 IPR024567 Ribonuclease HII/HIII domain TO73_2181 1b23cd7336a544f0de1fe0d266123080 200 Hamap MF_00052_B Ribonuclease HII [rnhB]. 14 190 32.643 T 11-10-2018 IPR022898 Ribonuclease HII GO:0004523 TO73_0222 c9472f40956d2f80da552dffe8f65268 276 Gene3D G3DSA:3.40.50.620 2 172 2.7E-78 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0222 c9472f40956d2f80da552dffe8f65268 276 Gene3D G3DSA:3.30.1300.10 173 276 5.4E-28 T 11-10-2018 TO73_0222 c9472f40956d2f80da552dffe8f65268 276 Pfam PF02569 Pantoate-beta-alanine ligase 5 272 1.4E-98 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TO73_0222 c9472f40956d2f80da552dffe8f65268 276 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 74 1.0E-7 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TO73_0222 c9472f40956d2f80da552dffe8f65268 276 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 274 1.6E-94 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TO73_0222 c9472f40956d2f80da552dffe8f65268 276 Hamap MF_00158 Pantothenate synthetase [panC]. 2 274 40.286 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TO73_0222 c9472f40956d2f80da552dffe8f65268 276 SUPERFAMILY SSF52374 5 274 6.7E-101 T 11-10-2018 TO73_0512 34667ec7cdba2d6133767835c3bea62e 148 Pfam PF00034 Cytochrome c 19 107 1.3E-8 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0512 34667ec7cdba2d6133767835c3bea62e 148 SUPERFAMILY SSF46626 19 131 1.04E-24 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0512 34667ec7cdba2d6133767835c3bea62e 148 Gene3D G3DSA:1.10.760.10 18 148 3.2E-51 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_2288 0dda46cd2e38ea41b9b813275e5aa806 204 Gene3D G3DSA:3.30.1130.10 72 204 1.6E-63 T 11-10-2018 TO73_2288 0dda46cd2e38ea41b9b813275e5aa806 204 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 29 202 6.8E-77 T 11-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TO73_2288 0dda46cd2e38ea41b9b813275e5aa806 204 SUPERFAMILY SSF55620 13 202 4.08E-79 T 11-10-2018 TO73_2288 0dda46cd2e38ea41b9b813275e5aa806 204 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 81 97 - T 11-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TO73_2288 0dda46cd2e38ea41b9b813275e5aa806 204 Pfam PF01227 GTP cyclohydrolase I 28 201 2.2E-75 T 11-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TO73_2288 0dda46cd2e38ea41b9b813275e5aa806 204 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 20 202 38.963 T 11-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TO73_2288 0dda46cd2e38ea41b9b813275e5aa806 204 Gene3D G3DSA:1.10.286.10 18 71 5.8E-24 T 11-10-2018 TO73_0974 0828ca7b89aadbc5e86f0e55ce4a1679 308 SUPERFAMILY SSF56349 36 302 1.21E-44 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TO73_0974 0828ca7b89aadbc5e86f0e55ce4a1679 308 Gene3D G3DSA:1.10.150.130 25 111 3.2E-8 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal TO73_0974 0828ca7b89aadbc5e86f0e55ce4a1679 308 Gene3D G3DSA:1.10.443.10 117 306 1.3E-42 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TO73_0974 0828ca7b89aadbc5e86f0e55ce4a1679 308 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 28 99 1.1E-7 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TO73_0974 0828ca7b89aadbc5e86f0e55ce4a1679 308 Pfam PF00589 Phage integrase family 129 294 1.1E-32 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TO73_0291 563dcf8d54de64918c44ea7b688720e7 431 Pfam PF01458 Uncharacterized protein family (UPF0051) 183 403 7.0E-67 T 11-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TO73_0291 563dcf8d54de64918c44ea7b688720e7 431 SUPERFAMILY SSF101960 8 429 8.5E-111 T 11-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TO73_0291 563dcf8d54de64918c44ea7b688720e7 431 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 147 420 1.8E-72 T 11-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 Pfam PF06480 FtsH Extracellular 9 99 1.9E-8 T 11-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 323 2.3E-43 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 Gene3D G3DSA:2.40.50.920 31 104 5.8E-6 T 11-10-2018 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 Gene3D G3DSA:1.20.58.760 405 600 2.5E-85 T 11-10-2018 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 606 36.858 T 11-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 106 591 4.8E-220 T 11-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 Gene3D G3DSA:3.40.50.300 142 325 6.6E-71 T 11-10-2018 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 Gene3D G3DSA:1.10.8.60 326 403 2.3E-32 T 11-10-2018 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 SUPERFAMILY SSF52540 148 396 9.81E-76 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 SUPERFAMILY SSF140990 406 600 2.75E-68 T 11-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 11-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 Pfam PF01434 Peptidase family M41 385 590 1.7E-74 T 11-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TO73_1924 8331de7f82875824ef8bb0ae7ec13eda 624 SMART SM00382 188 327 3.4E-24 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_2078 958e215d1b32ba76e2806f3ef85f1e74 230 Gene3D G3DSA:3.40.250.10 1 118 2.0E-27 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_2078 958e215d1b32ba76e2806f3ef85f1e74 230 ProSitePatterns PS00380 Rhodanese signature 1. 18 29 - T 11-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TO73_2078 958e215d1b32ba76e2806f3ef85f1e74 230 SMART SM00450 1 105 0.022 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_2078 958e215d1b32ba76e2806f3ef85f1e74 230 SMART SM00450 115 227 2.4E-19 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_2078 958e215d1b32ba76e2806f3ef85f1e74 230 Pfam PF00581 Rhodanese-like domain 7 99 5.9E-10 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_2078 958e215d1b32ba76e2806f3ef85f1e74 230 Pfam PF00581 Rhodanese-like domain 121 223 2.1E-9 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_2078 958e215d1b32ba76e2806f3ef85f1e74 230 SUPERFAMILY SSF52821 116 230 4.32E-24 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_2078 958e215d1b32ba76e2806f3ef85f1e74 230 SUPERFAMILY SSF52821 6 121 4.58E-13 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_2078 958e215d1b32ba76e2806f3ef85f1e74 230 Gene3D G3DSA:3.40.250.10 119 229 1.4E-30 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1469 7775eae3506c108a6edbb8690ab5cadc 247 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 116 1.9E-9 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TO73_1469 7775eae3506c108a6edbb8690ab5cadc 247 Gene3D G3DSA:3.10.180.10 155 231 9.7E-11 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_1469 7775eae3506c108a6edbb8690ab5cadc 247 SUPERFAMILY SSF54593 6 145 3.36E-34 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_1469 7775eae3506c108a6edbb8690ab5cadc 247 Gene3D G3DSA:3.10.180.10 1 148 4.1E-24 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_1469 7775eae3506c108a6edbb8690ab5cadc 247 SUPERFAMILY SSF54593 151 228 1.45E-14 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_2776 de431b5d7c716475b4977f610c9c2e38 157 Gene3D G3DSA:3.40.220.10 17 157 7.3E-14 T 11-10-2018 TO73_2776 de431b5d7c716475b4977f610c9c2e38 157 SUPERFAMILY SSF52949 4 155 1.13E-11 T 11-10-2018 TO73_2174 84b81926f1e93191234c684088cb8619 272 Gene3D G3DSA:3.20.20.20 1 272 1.6E-114 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_2174 84b81926f1e93191234c684088cb8619 272 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_2174 84b81926f1e93191234c684088cb8619 272 Pfam PF00809 Pterin binding enzyme 17 255 3.4E-83 T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_2174 84b81926f1e93191234c684088cb8619 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 270 1.1E-96 T 11-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TO73_2174 84b81926f1e93191234c684088cb8619 272 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_2174 84b81926f1e93191234c684088cb8619 272 SUPERFAMILY SSF51717 5 272 7.06E-100 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TO73_2873 c13c0ea69514044bc3a23a4dfb918101 303 SUPERFAMILY SSF110296 28 293 1.41E-15 T 11-10-2018 TO73_1494 7f084c13776bf68962e9bba866decfcb 345 Pfam PF01180 Dihydroorotate dehydrogenase 45 332 5.1E-85 T 11-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TO73_1494 7f084c13776bf68962e9bba866decfcb 345 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 11-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TO73_1494 7f084c13776bf68962e9bba866decfcb 345 PIRSF PIRSF000164 10 344 9.4E-100 T 11-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 TO73_1494 7f084c13776bf68962e9bba866decfcb 345 SUPERFAMILY SSF51395 3 344 1.24E-97 T 11-10-2018 TO73_1494 7f084c13776bf68962e9bba866decfcb 345 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 328 46.42 T 11-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TO73_1494 7f084c13776bf68962e9bba866decfcb 345 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 1 342 5.8E-115 T 11-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TO73_1494 7f084c13776bf68962e9bba866decfcb 345 Gene3D G3DSA:3.20.20.70 1 345 4.6E-120 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0244 25f08b31f1ec2540dae225f2992393f4 164 Gene3D G3DSA:1.20.58.1290 62 160 1.5E-38 T 11-10-2018 TO73_0244 25f08b31f1ec2540dae225f2992393f4 164 SMART SM01058 3 113 1.2E-20 T 11-10-2018 IPR003711 CarD-like/TRCF domain TO73_0244 25f08b31f1ec2540dae225f2992393f4 164 Pfam PF02559 CarD-like/TRCF domain 4 108 2.0E-13 T 11-10-2018 IPR003711 CarD-like/TRCF domain TO73_0244 25f08b31f1ec2540dae225f2992393f4 164 SUPERFAMILY SSF141259 2 69 4.71E-12 T 11-10-2018 IPR036101 CarD-like/TRCF domain superfamily TO73_0244 25f08b31f1ec2540dae225f2992393f4 164 Gene3D G3DSA:2.30.30.840 1 61 1.7E-18 T 11-10-2018 TO73_0785 7a482b20ae8213d2df62a6e965caa740 76 SUPERFAMILY SSF51735 12 71 4.92E-8 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0785 7a482b20ae8213d2df62a6e965caa740 76 Gene3D G3DSA:3.40.50.720 1 74 4.2E-15 T 11-10-2018 TO73_0785 7a482b20ae8213d2df62a6e965caa740 76 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 69 1.5E-12 T 11-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TO73_2395 1df9d98351c4a77f497e71231484911f 131 Pfam PF06262 Zincin-like metallopeptidase 25 118 2.2E-19 T 11-10-2018 IPR010428 Zincin-like metallopeptidase TO73_2395 1df9d98351c4a77f497e71231484911f 131 SUPERFAMILY SSF55486 2 107 1.5E-26 T 11-10-2018 TO73_2395 1df9d98351c4a77f497e71231484911f 131 Gene3D G3DSA:3.30.2010.20 1 130 7.0E-45 T 11-10-2018 IPR038555 Zincin-like metallopeptidase superfamily TO73_0398 2e066c96e228a683cb66066450c06439 255 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 166 184 - T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TO73_0398 2e066c96e228a683cb66066450c06439 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 247 3.5E-92 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TO73_0398 2e066c96e228a683cb66066450c06439 255 Hamap MF_01974 Methionine aminopeptidase [map]. 3 249 39.058 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TO73_0398 2e066c96e228a683cb66066450c06439 255 Gene3D G3DSA:3.90.230.10 1 251 3.1E-99 T 11-10-2018 TO73_0398 2e066c96e228a683cb66066450c06439 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 68 81 1.6E-20 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TO73_0398 2e066c96e228a683cb66066450c06439 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 1.6E-20 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TO73_0398 2e066c96e228a683cb66066450c06439 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 160 172 1.6E-20 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TO73_0398 2e066c96e228a683cb66066450c06439 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 1.6E-20 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TO73_0398 2e066c96e228a683cb66066450c06439 255 Pfam PF00557 Metallopeptidase family M24 12 240 7.5E-54 T 11-10-2018 IPR000994 Peptidase M24 TO73_0398 2e066c96e228a683cb66066450c06439 255 SUPERFAMILY SSF55920 4 249 1.83E-84 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like TO73_1782 1498c58db2773c7778783260adc7e5c0 576 ProSitePatterns PS00331 Malic enzymes signature. 275 291 - T 11-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 PRINTS PR00072 Malic enzyme signature 415 431 1.3E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 PRINTS PR00072 Malic enzyme signature 95 119 1.3E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 PRINTS PR00072 Malic enzyme signature 275 291 1.3E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 PRINTS PR00072 Malic enzyme signature 250 268 1.3E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 PRINTS PR00072 Malic enzyme signature 191 213 1.3E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 PRINTS PR00072 Malic enzyme signature 306 322 1.3E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 PRINTS PR00072 Malic enzyme signature 155 184 1.3E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 PIRSF PIRSF000106 3 573 7.3E-210 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 Gene3D G3DSA:3.40.50.10380 23 276 2.3E-103 T 11-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 Pfam PF00390 Malic enzyme, N-terminal domain 89 269 7.8E-73 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 SMART SM00919 279 536 4.2E-115 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 SUPERFAMILY SSF51735 279 572 7.04E-84 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1782 1498c58db2773c7778783260adc7e5c0 576 SUPERFAMILY SSF53223 9 278 3.6E-103 T 11-10-2018 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 Gene3D G3DSA:3.40.50.720 277 574 1.7E-100 T 11-10-2018 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 Pfam PF03949 Malic enzyme, NAD binding domain 279 535 3.8E-90 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TO73_1782 1498c58db2773c7778783260adc7e5c0 576 SMART SM01274 89 269 6.9E-97 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TO73_1696 e27c3e5fc9628632869336d5613be5c2 670 PIRSF PIRSF000549 1 668 1.4E-248 T 11-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 TO73_1696 e27c3e5fc9628632869336d5613be5c2 670 Pfam PF08298 PrkA AAA domain 24 404 1.2E-89 T 11-10-2018 IPR013153 PrkA AAA domain TO73_1696 e27c3e5fc9628632869336d5613be5c2 670 Pfam PF06798 PrkA serine protein kinase C-terminal domain 410 660 4.1E-86 T 11-10-2018 IPR010650 PrkA C-terminal domain TO73_1696 e27c3e5fc9628632869336d5613be5c2 670 SMART SM00763 23 406 3.4E-207 T 11-10-2018 IPR013153 PrkA AAA domain TO73_1696 e27c3e5fc9628632869336d5613be5c2 670 SUPERFAMILY SSF52540 80 442 4.67E-13 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1737 070859cee32dd6e2bcb15ff49e0e0213 405 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 88 102 - T 11-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TO73_1737 070859cee32dd6e2bcb15ff49e0e0213 405 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 9 401 53.362 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TO73_1737 070859cee32dd6e2bcb15ff49e0e0213 405 SUPERFAMILY SSF53686 10 399 7.99E-149 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TO73_1737 070859cee32dd6e2bcb15ff49e0e0213 405 PIRSF PIRSF001413 3 405 5.7E-159 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TO73_1737 070859cee32dd6e2bcb15ff49e0e0213 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 60 388 6.1E-52 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TO73_1737 070859cee32dd6e2bcb15ff49e0e0213 405 Gene3D G3DSA:3.40.50.1100 61 394 2.6E-182 T 11-10-2018 TO73_1737 070859cee32dd6e2bcb15ff49e0e0213 405 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 14 399 1.6E-184 T 11-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TO73_1737 070859cee32dd6e2bcb15ff49e0e0213 405 Gene3D G3DSA:3.40.50.1100 17 213 2.6E-182 T 11-10-2018 TO73_1054 2b04e262cfb342c04b34a43caa3ad671 137 SUPERFAMILY SSF52402 2 137 4.35E-36 T 11-10-2018 TO73_1054 2b04e262cfb342c04b34a43caa3ad671 137 PRINTS PR01438 Universal stress protein signature 97 109 2.3E-20 T 11-10-2018 IPR006015 Universal stress protein A TO73_1054 2b04e262cfb342c04b34a43caa3ad671 137 PRINTS PR01438 Universal stress protein signature 2 20 2.3E-20 T 11-10-2018 IPR006015 Universal stress protein A TO73_1054 2b04e262cfb342c04b34a43caa3ad671 137 PRINTS PR01438 Universal stress protein signature 115 137 2.3E-20 T 11-10-2018 IPR006015 Universal stress protein A TO73_1054 2b04e262cfb342c04b34a43caa3ad671 137 Pfam PF00582 Universal stress protein family 1 137 2.3E-34 T 11-10-2018 IPR006016 UspA TO73_1054 2b04e262cfb342c04b34a43caa3ad671 137 Gene3D G3DSA:3.40.50.620 1 137 1.2E-46 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0393 3d673e6731dd3886dfb0fd2f6fa62bfa 157 Pfam PF00333 Ribosomal protein S5, N-terminal domain 6 70 1.5E-24 T 11-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TO73_0393 3d673e6731dd3886dfb0fd2f6fa62bfa 157 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 157 32.145 T 11-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TO73_0393 3d673e6731dd3886dfb0fd2f6fa62bfa 157 SUPERFAMILY SSF54211 74 152 1.39E-24 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0393 3d673e6731dd3886dfb0fd2f6fa62bfa 157 SUPERFAMILY SSF54768 4 71 5.13E-21 T 11-10-2018 TO73_0393 3d673e6731dd3886dfb0fd2f6fa62bfa 157 ProSitePatterns PS00585 Ribosomal protein S5 signature. 23 55 - T 11-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site TO73_0393 3d673e6731dd3886dfb0fd2f6fa62bfa 157 Gene3D G3DSA:3.30.160.20 1 68 1.2E-28 T 11-10-2018 TO73_0393 3d673e6731dd3886dfb0fd2f6fa62bfa 157 Gene3D G3DSA:3.30.230.10 69 157 1.8E-34 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0393 3d673e6731dd3886dfb0fd2f6fa62bfa 157 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 3 154 3.6E-62 T 11-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TO73_0393 3d673e6731dd3886dfb0fd2f6fa62bfa 157 Pfam PF03719 Ribosomal protein S5, C-terminal domain 82 152 1.3E-29 T 11-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TO73_2365 df4c18c6b433476c7167e98cf2e36529 392 Pfam PF12679 ABC-2 family transporter protein 5 387 2.8E-24 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TO73_0909 a6722f61b74291dd4826c1eabe7eaee9 254 Gene3D G3DSA:3.40.50.300 1 250 7.1E-65 T 11-10-2018 TO73_0909 a6722f61b74291dd4826c1eabe7eaee9 254 Pfam PF00005 ABC transporter 21 170 1.8E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0909 a6722f61b74291dd4826c1eabe7eaee9 254 SMART SM00382 28 227 4.9E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0909 a6722f61b74291dd4826c1eabe7eaee9 254 SUPERFAMILY SSF52540 3 249 1.09E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0909 a6722f61b74291dd4826c1eabe7eaee9 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 249 3.5E-11 T 11-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TO73_0909 a6722f61b74291dd4826c1eabe7eaee9 254 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 SUPERFAMILY SSF110324 2 81 2.2E-33 T 11-10-2018 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 77 2.4E-38 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 28.567 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 85 5.0E-24 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 11-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 Pfam PF01016 Ribosomal L27 protein 2 81 1.6E-37 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 Gene3D G3DSA:2.40.50.100 20 85 2.1E-31 T 11-10-2018 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.4E-37 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.4E-37 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0215 2e192817a9684bf29c70be24c97b7e3f 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.4E-37 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0743 c1d62ed81aacf8e02583702ee9520b95 440 Pfam PF01546 Peptidase family M20/M25/M40 69 435 5.8E-34 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 TO73_0743 c1d62ed81aacf8e02583702ee9520b95 440 SUPERFAMILY SSF53187 4 438 6.01E-54 T 11-10-2018 TO73_0743 c1d62ed81aacf8e02583702ee9520b95 440 Gene3D G3DSA:3.30.70.360 182 351 3.6E-147 T 11-10-2018 TO73_0743 c1d62ed81aacf8e02583702ee9520b95 440 Pfam PF07687 Peptidase dimerisation domain 180 338 7.8E-19 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain TO73_0743 c1d62ed81aacf8e02583702ee9520b95 440 Gene3D G3DSA:3.40.630.10 15 423 3.6E-147 T 11-10-2018 TO73_0124 b6b49a2a3e6ca34f0a1cb19cd7b789cb 450 PIRSF PIRSF000204 1 449 1.4E-162 T 11-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 TO73_0124 b6b49a2a3e6ca34f0a1cb19cd7b789cb 450 Gene3D G3DSA:3.40.50.1220 266 450 4.7E-86 T 11-10-2018 TO73_0124 b6b49a2a3e6ca34f0a1cb19cd7b789cb 450 Pfam PF02233 NAD(P) transhydrogenase beta subunit 5 445 2.0E-175 T 11-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 TO73_0124 b6b49a2a3e6ca34f0a1cb19cd7b789cb 450 SUPERFAMILY SSF52467 276 449 6.55E-72 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TO73_1757 3a6df69b0f61d81615b3a31947b54bce 511 SUPERFAMILY SSF51735 370 497 9.73E-23 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1757 3a6df69b0f61d81615b3a31947b54bce 511 Pfam PF02254 TrkA-N domain 370 484 4.4E-17 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TO73_1757 3a6df69b0f61d81615b3a31947b54bce 511 Gene3D G3DSA:1.20.1530.20 3 342 9.7E-36 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily TO73_1757 3a6df69b0f61d81615b3a31947b54bce 511 Gene3D G3DSA:3.40.50.720 365 503 8.5E-33 T 11-10-2018 TO73_1757 3a6df69b0f61d81615b3a31947b54bce 511 Pfam PF00999 Sodium/hydrogen exchanger family 4 327 4.5E-25 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TO73_1243 6af96acc07bf7797f39f4bbd527467ac 184 Pfam PF09459 Ethylbenzene dehydrogenase 73 162 8.2E-10 T 11-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 TO73_1243 6af96acc07bf7797f39f4bbd527467ac 184 Pfam PF03351 DOMON domain 42 160 1.6E-18 T 11-10-2018 IPR005018 DOMON domain TO73_2391 d0d387e8d4cce017dc9f1c8ac913e0a6 242 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 31 220 4.2E-44 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TO73_2391 d0d387e8d4cce017dc9f1c8ac913e0a6 242 SUPERFAMILY SSF53335 25 241 2.84E-37 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2391 d0d387e8d4cce017dc9f1c8ac913e0a6 242 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 19 218 26.2 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TO73_2391 d0d387e8d4cce017dc9f1c8ac913e0a6 242 PIRSF PIRSF003078 11 223 2.2E-47 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TO73_2391 d0d387e8d4cce017dc9f1c8ac913e0a6 242 Gene3D G3DSA:3.40.50.150 2 242 7.0E-83 T 11-10-2018 TO73_2391 d0d387e8d4cce017dc9f1c8ac913e0a6 242 Pfam PF02527 rRNA small subunit methyltransferase G 27 205 2.9E-41 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TO73_0111 43df45f5b8636af027af2ad5c36afeb7 204 SUPERFAMILY SSF54106 18 61 4.32E-13 T 11-10-2018 TO73_0111 43df45f5b8636af027af2ad5c36afeb7 204 Pfam PF01476 LysM domain 19 61 2.0E-15 T 11-10-2018 IPR018392 LysM domain TO73_0111 43df45f5b8636af027af2ad5c36afeb7 204 SMART SM00257 18 61 7.8E-19 T 11-10-2018 IPR018392 LysM domain TO73_0111 43df45f5b8636af027af2ad5c36afeb7 204 Gene3D G3DSA:3.10.350.10 16 62 2.9E-23 T 11-10-2018 IPR036779 LysM domain superfamily TO73_0111 43df45f5b8636af027af2ad5c36afeb7 204 Gene3D G3DSA:3.90.1720.10 77 203 6.5E-36 T 11-10-2018 TO73_0111 43df45f5b8636af027af2ad5c36afeb7 204 Pfam PF00877 NlpC/P60 family 93 196 9.8E-25 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain TO73_0111 43df45f5b8636af027af2ad5c36afeb7 204 SUPERFAMILY SSF54001 83 199 1.45E-36 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TO73_0468 6d2d39dd6e7503fcbe018e3ba3e7292c 124 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 105 1.4E-19 T 11-10-2018 IPR028090 JAB domain, prokaryotic TO73_0468 6d2d39dd6e7503fcbe018e3ba3e7292c 124 SMART SM00232 1 124 0.0018 T 11-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 TO73_0468 6d2d39dd6e7503fcbe018e3ba3e7292c 124 SUPERFAMILY SSF102712 1 119 1.83E-21 T 11-10-2018 TO73_0468 6d2d39dd6e7503fcbe018e3ba3e7292c 124 Gene3D G3DSA:3.40.140.10 1 124 1.5E-26 T 11-10-2018 TO73_1563 5016c4e1d4429e7a180279517d78f28d 238 Gene3D G3DSA:3.90.1560.10 11 217 1.1E-22 T 11-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TO73_1563 5016c4e1d4429e7a180279517d78f28d 238 Pfam PF04029 2-phosphosulpholactate phosphatase 17 213 9.2E-23 T 11-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TO73_1563 5016c4e1d4429e7a180279517d78f28d 238 SUPERFAMILY SSF142823 11 216 4.32E-23 T 11-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TO73_1998 70acef09a76729246ee88c57b391e0ae 333 Pfam PF02481 DNA recombination-mediator protein A 57 255 2.2E-67 T 11-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TO73_1998 70acef09a76729246ee88c57b391e0ae 333 Gene3D G3DSA:3.40.50.450 1 266 3.5E-86 T 11-10-2018 TO73_1998 70acef09a76729246ee88c57b391e0ae 333 SUPERFAMILY SSF102405 68 265 1.68E-40 T 11-10-2018 TO73_1998 70acef09a76729246ee88c57b391e0ae 333 SUPERFAMILY SSF46785 273 329 1.35E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1998 70acef09a76729246ee88c57b391e0ae 333 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 67 263 1.3E-63 T 11-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TO73_0700 bf32cb8889acc504c3987bcab218fe1a 551 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 26 549 1.1E-232 T 11-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TO73_0700 bf32cb8889acc504c3987bcab218fe1a 551 Gene3D G3DSA:3.20.20.240 1 551 3.5E-250 T 11-10-2018 TO73_0700 bf32cb8889acc504c3987bcab218fe1a 551 Pfam PF01642 Methylmalonyl-CoA mutase 27 543 2.6E-226 T 11-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TO73_0700 bf32cb8889acc504c3987bcab218fe1a 551 SUPERFAMILY SSF51703 4 545 2.55E-215 T 11-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TO73_0625 924e0bc233a60c5bf59addc7f0cd583e 984 SUPERFAMILY SSF53335 65 650 8.85E-37 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_0625 924e0bc233a60c5bf59addc7f0cd583e 984 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 274 288 6.0E-10 T 11-10-2018 TO73_0625 924e0bc233a60c5bf59addc7f0cd583e 984 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 222 238 6.0E-10 T 11-10-2018 TO73_0625 924e0bc233a60c5bf59addc7f0cd583e 984 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 489 501 6.0E-10 T 11-10-2018 TO73_0625 924e0bc233a60c5bf59addc7f0cd583e 984 Pfam PF02384 N-6 DNA Methylase 202 294 3.2E-7 T 11-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TO73_2157 a872bc8177170e863b477ed52091cf76 249 TIGRFAM TIGR00761 argB: acetylglutamate kinase 5 223 2.2E-54 T 11-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_2157 a872bc8177170e863b477ed52091cf76 249 Gene3D G3DSA:3.40.1160.10 2 249 2.9E-61 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_2157 a872bc8177170e863b477ed52091cf76 249 SUPERFAMILY SSF53633 4 247 6.02E-51 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TO73_2157 a872bc8177170e863b477ed52091cf76 249 Hamap MF_00082 Acetylglutamate kinase [argB]. 2 243 41.375 T 11-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_2157 a872bc8177170e863b477ed52091cf76 249 PIRSF PIRSF000728 2 247 1.6E-70 T 11-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TO73_2157 a872bc8177170e863b477ed52091cf76 249 Pfam PF00696 Amino acid kinase family 5 220 1.2E-34 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TO73_1289 b563d80b97324275f66ba2cde944ec1a 235 SUPERFAMILY SSF51366 1 233 3.03E-62 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TO73_1289 b563d80b97324275f66ba2cde944ec1a 235 Pfam PF00977 Histidine biosynthesis protein 3 226 1.1E-65 T 11-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TO73_1289 b563d80b97324275f66ba2cde944ec1a 235 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 234 32.374 T 11-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TO73_1289 b563d80b97324275f66ba2cde944ec1a 235 Gene3D G3DSA:3.20.20.70 1 235 4.0E-80 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0231 6ce3d20e92ba2ff37e9aa8414b85d2ea 534 Pfam PF14326 Domain of unknown function (DUF4384) 50 130 1.1E-26 T 11-10-2018 IPR025493 Domain of unknown function DUF4384 TO73_0231 6ce3d20e92ba2ff37e9aa8414b85d2ea 534 Pfam PF08308 PEGA domain 257 323 2.4E-20 T 11-10-2018 IPR013229 PEGA TO73_0231 6ce3d20e92ba2ff37e9aa8414b85d2ea 534 Pfam PF08308 PEGA domain 476 531 2.9E-6 T 11-10-2018 IPR013229 PEGA TO73_0231 6ce3d20e92ba2ff37e9aa8414b85d2ea 534 Pfam PF08308 PEGA domain 187 252 7.0E-18 T 11-10-2018 IPR013229 PEGA TO73_0231 6ce3d20e92ba2ff37e9aa8414b85d2ea 534 Pfam PF08308 PEGA domain 328 394 2.9E-17 T 11-10-2018 IPR013229 PEGA TO73_0231 6ce3d20e92ba2ff37e9aa8414b85d2ea 534 Pfam PF08308 PEGA domain 398 464 1.7E-18 T 11-10-2018 IPR013229 PEGA TO73_0682 c2495f11e3ee6e458dddf5eb4fb219d6 220 PIRSF PIRSF036692 1 217 3.3E-78 T 11-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 TO73_0682 c2495f11e3ee6e458dddf5eb4fb219d6 220 SUPERFAMILY SSF55021 134 215 4.04E-15 T 11-10-2018 TO73_0682 c2495f11e3ee6e458dddf5eb4fb219d6 220 Gene3D G3DSA:3.30.1330.90 10 131 3.0E-18 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TO73_0682 c2495f11e3ee6e458dddf5eb4fb219d6 220 Pfam PF03315 Serine dehydratase beta chain 10 72 2.2E-11 T 11-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 TO73_0682 c2495f11e3ee6e458dddf5eb4fb219d6 220 SUPERFAMILY SSF143548 16 132 2.88E-29 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TO73_0682 c2495f11e3ee6e458dddf5eb4fb219d6 220 Pfam PF01842 ACT domain 146 193 2.6E-7 T 11-10-2018 IPR002912 ACT domain TO73_0682 c2495f11e3ee6e458dddf5eb4fb219d6 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 4 197 2.4E-63 T 11-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 TO73_0682 c2495f11e3ee6e458dddf5eb4fb219d6 220 Gene3D G3DSA:3.30.70.260 144 215 2.6E-14 T 11-10-2018 TO73_1326 e64680a878712bae16e04441bf97f9be 173 Pfam PF05685 Putative restriction endonuclease 9 169 3.3E-26 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1326 e64680a878712bae16e04441bf97f9be 173 Gene3D G3DSA:3.90.1570.10 3 157 9.1E-10 T 11-10-2018 TO73_1326 e64680a878712bae16e04441bf97f9be 173 SUPERFAMILY SSF52980 5 171 2.73E-18 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_0741 e8f7679b5a83587de10b58d837bd5d07 196 SUPERFAMILY SSF52540 10 189 1.48E-22 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0741 e8f7679b5a83587de10b58d837bd5d07 196 Gene3D G3DSA:3.40.50.300 1 195 8.9E-91 T 11-10-2018 TO73_0741 e8f7679b5a83587de10b58d837bd5d07 196 Pfam PF00025 ADP-ribosylation factor family 66 185 7.1E-6 T 11-10-2018 IPR006689 Small GTPase superfamily, ARF/SAR type GO:0005525 TO73_1091 e6d3aef6ed9eabb26e13a61f3fb8336d 380 SUPERFAMILY SSF53474 36 379 6.27E-92 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_1091 e6d3aef6ed9eabb26e13a61f3fb8336d 380 PRINTS PR00111 Alpha/beta hydrolase fold signature 196 209 1.5E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_1091 e6d3aef6ed9eabb26e13a61f3fb8336d 380 PRINTS PR00111 Alpha/beta hydrolase fold signature 182 195 1.5E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_1091 e6d3aef6ed9eabb26e13a61f3fb8336d 380 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 41 379 1.5E-121 T 11-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TO73_1091 e6d3aef6ed9eabb26e13a61f3fb8336d 380 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 29 380 30.823 T 11-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TO73_1091 e6d3aef6ed9eabb26e13a61f3fb8336d 380 Gene3D G3DSA:3.40.50.1820 39 380 1.6E-122 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_1091 e6d3aef6ed9eabb26e13a61f3fb8336d 380 PIRSF PIRSF000443 30 380 6.0E-108 T 11-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TO73_1091 e6d3aef6ed9eabb26e13a61f3fb8336d 380 Pfam PF00561 alpha/beta hydrolase fold 70 366 1.9E-23 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 31 42 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 SUPERFAMILY SSF52374 25 341 1.29E-91 T 11-10-2018 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 25 335 5.3E-99 T 11-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 Gene3D G3DSA:2.40.240.10 460 544 1.5E-26 T 11-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 338 525 9.8E-47 T 11-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 Gene3D G3DSA:3.40.50.620 6 341 1.0E-128 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 25 546 9.5E-190 T 11-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 Gene3D G3DSA:2.40.240.10 346 459 7.2E-35 T 11-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 40 1.0E-11 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 PRINTS PR00987 Glutamyl-tRNA synthetase signature 202 212 1.0E-11 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 PRINTS PR00987 Glutamyl-tRNA synthetase signature 57 70 1.0E-11 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 53 1.0E-11 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TO73_1355 f6d124e8c938f6ff6bc37017491aefed 549 SUPERFAMILY SSF50715 338 544 3.5E-60 T 11-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_0606 e1da5c9f9e7e62113e801ab680090a44 147 Gene3D G3DSA:2.40.33.20 1 146 9.7E-24 T 11-10-2018 TO73_0606 e1da5c9f9e7e62113e801ab680090a44 147 SUPERFAMILY SSF50800 1 143 1.62E-26 T 11-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TO73_0606 e1da5c9f9e7e62113e801ab680090a44 147 Pfam PF03473 MOSC domain 55 140 5.0E-6 T 11-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 TO73_1391 9de9b4d0ce469a954ddf9e7a09d8f0d3 137 SUPERFAMILY SSF46785 15 131 7.26E-33 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1391 9de9b4d0ce469a954ddf9e7a09d8f0d3 137 Pfam PF01475 Ferric uptake regulator family 15 109 7.1E-22 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TO73_1391 9de9b4d0ce469a954ddf9e7a09d8f0d3 137 Gene3D G3DSA:1.10.10.10 3 83 2.0E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1391 9de9b4d0ce469a954ddf9e7a09d8f0d3 137 Gene3D G3DSA:3.30.1490.190 86 136 5.8E-12 T 11-10-2018 TO73_0923 d04e441ecc7de68e059483344e9755a3 536 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 2 16 - T 11-10-2018 IPR019775 WD40 repeat, conserved site TO73_0923 d04e441ecc7de68e059483344e9755a3 536 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 11-10-2018 IPR020845 AMP-binding, conserved site TO73_0923 d04e441ecc7de68e059483344e9755a3 536 Pfam PF00501 AMP-binding enzyme 18 434 3.7E-99 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_0923 d04e441ecc7de68e059483344e9755a3 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 518 7.6E-19 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TO73_0923 d04e441ecc7de68e059483344e9755a3 536 SUPERFAMILY SSF56801 4 530 7.33E-149 T 11-10-2018 TO73_0923 d04e441ecc7de68e059483344e9755a3 536 Gene3D G3DSA:3.30.300.310 430 534 1.2E-39 T 11-10-2018 TO73_0923 d04e441ecc7de68e059483344e9755a3 536 Gene3D G3DSA:3.40.50.12780 1 429 7.5E-175 T 11-10-2018 TO73_0478 fee2a52728cce422770a8d28722bb1b3 452 Pfam PF00395 S-layer homology domain 73 115 1.0E-8 T 11-10-2018 IPR001119 S-layer homology domain TO73_0478 fee2a52728cce422770a8d28722bb1b3 452 Pfam PF00395 S-layer homology domain 13 54 1.1E-5 T 11-10-2018 IPR001119 S-layer homology domain TO73_0478 fee2a52728cce422770a8d28722bb1b3 452 Pfam PF00395 S-layer homology domain 136 176 7.6E-6 T 11-10-2018 IPR001119 S-layer homology domain TO73_2209 a6e9f89f51556edeb1c637f390bf1b08 317 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 36 312 1.1E-68 T 11-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 TO73_2209 a6e9f89f51556edeb1c637f390bf1b08 317 Gene3D G3DSA:1.10.3720.10 86 315 9.0E-35 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2209 a6e9f89f51556edeb1c637f390bf1b08 317 SUPERFAMILY SSF161098 35 307 3.01E-34 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2209 a6e9f89f51556edeb1c637f390bf1b08 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 313 2.2E-17 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 SUPERFAMILY SSF52172 1 129 1.37E-30 T 11-10-2018 IPR011006 CheY-like superfamily TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 SMART SM00421 144 201 9.8E-21 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 SMART SM00448 2 115 2.3E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 1.2E-20 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 Gene3D G3DSA:3.40.50.12740 2 207 1.1E-62 T 11-10-2018 TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 SUPERFAMILY SSF46894 133 207 7.82E-22 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 Pfam PF00072 Response regulator receiver domain 4 115 2.4E-23 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 1.2E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 1.2E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1236 9e565a7be9931037178e1a83a7d0a757 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 1.2E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1978 1b427a4051cc92a57ee7d6fc9720e94b 124 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 122 1.1E-48 T 11-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 TO73_1978 1b427a4051cc92a57ee7d6fc9720e94b 124 Gene3D G3DSA:3.30.1330.40 1 124 2.4E-56 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TO73_1978 1b427a4051cc92a57ee7d6fc9720e94b 124 SUPERFAMILY SSF55298 3 122 1.45E-45 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TO73_1978 1b427a4051cc92a57ee7d6fc9720e94b 124 Pfam PF01042 Endoribonuclease L-PSP 7 122 6.7E-42 T 11-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TO73_0970 8e964bfa1bf99c7e264d2a29ea7d75bc 150 SUPERFAMILY SSF54637 2 148 1.66E-46 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_0970 8e964bfa1bf99c7e264d2a29ea7d75bc 150 Pfam PF01575 MaoC like domain 10 114 8.1E-30 T 11-10-2018 IPR002539 MaoC-like dehydratase domain TO73_0970 8e964bfa1bf99c7e264d2a29ea7d75bc 150 Gene3D G3DSA:3.10.129.10 2 150 3.9E-57 T 11-10-2018 TO73_0145 ca55c3b7a489a906a0c00fd360404b2c 267 Gene3D G3DSA:1.10.8.900 151 252 3.4E-88 T 11-10-2018 TO73_0145 ca55c3b7a489a906a0c00fd360404b2c 267 SUPERFAMILY SSF53335 12 245 3.77E-31 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_0145 ca55c3b7a489a906a0c00fd360404b2c 267 Gene3D G3DSA:3.40.50.150 13 255 3.4E-88 T 11-10-2018 TO73_0145 ca55c3b7a489a906a0c00fd360404b2c 267 Pfam PF08241 Methyltransferase domain 48 141 1.9E-18 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TO73_1448 a8db8f7923184e2b1a436cdf3a061fb0 627 ProSitePatterns PS00455 Putative AMP-binding domain signature. 255 266 - T 11-10-2018 IPR020845 AMP-binding, conserved site TO73_1448 a8db8f7923184e2b1a436cdf3a061fb0 627 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 81 6.8E-19 T 11-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TO73_1448 a8db8f7923184e2b1a436cdf3a061fb0 627 SUPERFAMILY SSF56801 29 616 1.15E-165 T 11-10-2018 TO73_1448 a8db8f7923184e2b1a436cdf3a061fb0 627 Gene3D G3DSA:3.40.50.12780 54 511 4.6E-100 T 11-10-2018 TO73_1448 a8db8f7923184e2b1a436cdf3a061fb0 627 Pfam PF00501 AMP-binding enzyme 84 517 1.4E-86 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_1448 a8db8f7923184e2b1a436cdf3a061fb0 627 Pfam PF13193 AMP-binding enzyme C-terminal domain 527 604 7.4E-31 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TO73_1448 a8db8f7923184e2b1a436cdf3a061fb0 627 Gene3D G3DSA:3.30.300.30 513 626 6.9E-31 T 11-10-2018 TO73_2000 d614aa0cf0abc4ae2368098d6699d10d 293 SUPERFAMILY SSF51161 106 248 1.34E-37 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily TO73_2000 d614aa0cf0abc4ae2368098d6699d10d 293 Gene3D G3DSA:2.160.10.10 77 251 6.4E-36 T 11-10-2018 TO73_2000 d614aa0cf0abc4ae2368098d6699d10d 293 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 196 230 5.1E-5 T 11-10-2018 IPR001451 Hexapeptide repeat TO73_2099 77a301a86ed9aa7c0e39ad2f92852f3f 97 Pfam PF03641 Possible lysine decarboxylase 2 92 2.7E-23 T 11-10-2018 IPR031100 LOG family TO73_2099 77a301a86ed9aa7c0e39ad2f92852f3f 97 Gene3D G3DSA:3.40.50.450 1 96 5.7E-29 T 11-10-2018 TO73_2099 77a301a86ed9aa7c0e39ad2f92852f3f 97 SUPERFAMILY SSF102405 2 94 1.18E-28 T 11-10-2018 TO73_1954 537e5a56ac349c3e73c45051cb4a8e67 384 Gene3D G3DSA:1.20.1530.20 3 383 4.6E-137 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily TO73_1954 537e5a56ac349c3e73c45051cb4a8e67 384 Pfam PF00999 Sodium/hydrogen exchanger family 11 377 7.4E-68 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TO73_0738 add8609ae098b412b9f5233ea234d9dc 563 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 230 284 - T 11-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0738 add8609ae098b412b9f5233ea234d9dc 563 Gene3D G3DSA:1.20.210.10 3 563 7.8E-157 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0738 add8609ae098b412b9f5233ea234d9dc 563 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 18 470 2.8E-83 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0738 add8609ae098b412b9f5233ea234d9dc 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 430 451 1.1E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0738 add8609ae098b412b9f5233ea234d9dc 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 8 33 1.1E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0738 add8609ae098b412b9f5233ea234d9dc 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 228 249 1.1E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0738 add8609ae098b412b9f5233ea234d9dc 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 299 320 1.1E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0738 add8609ae098b412b9f5233ea234d9dc 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 130 142 1.1E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0738 add8609ae098b412b9f5233ea234d9dc 563 SUPERFAMILY SSF81442 14 561 2.09E-110 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 SUPERFAMILY SSF50615 3 70 2.67E-11 T 11-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 Gene3D G3DSA:2.40.30.20 1 71 1.7E-30 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 420 429 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 SUPERFAMILY SSF47917 442 548 4.71E-25 T 11-10-2018 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 Gene3D G3DSA:2.40.50.100 115 181 3.2E-180 T 11-10-2018 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 Gene3D G3DSA:1.10.1140.10 430 578 7.6E-51 T 11-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 577 50.889 T 11-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 Gene3D G3DSA:3.40.50.300 73 429 3.2E-180 T 11-10-2018 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 199 5.5E-43 T 11-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 SUPERFAMILY SSF52540 145 433 1.11E-80 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 5.5E-14 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1594 91d4f8afbe8916cafafae3e6112a5794 578 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 208 429 4.6E-90 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_1106 1372ecc7b7550b587cac54de75245d2e 382 SUPERFAMILY SSF53187 200 379 1.13E-16 T 11-10-2018 TO73_1106 1372ecc7b7550b587cac54de75245d2e 382 Gene3D G3DSA:3.40.630.40 195 381 4.9E-18 T 11-10-2018 TO73_1106 1372ecc7b7550b587cac54de75245d2e 382 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 202 375 9.2E-12 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TO73_1821 9d3d14d159077daab65dd3b1fb1b05d6 201 Pfam PF03692 Putative zinc- or iron-chelating domain 27 111 5.0E-5 T 11-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TO73_0795 c8b1aab4dfc58d17e9f00c358193899d 416 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 381 1.3E-4 T 11-10-2018 IPR019489 Clp ATPase, C-terminal TO73_0795 c8b1aab4dfc58d17e9f00c358193899d 416 Pfam PF07724 AAA domain (Cdc48 subfamily) 188 305 1.4E-37 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_0795 c8b1aab4dfc58d17e9f00c358193899d 416 SUPERFAMILY SSF52540 2 409 1.8E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0795 c8b1aab4dfc58d17e9f00c358193899d 416 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 121 6.9E-7 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TO73_0795 c8b1aab4dfc58d17e9f00c358193899d 416 SMART SM01086 311 404 1.5E-10 T 11-10-2018 IPR019489 Clp ATPase, C-terminal TO73_0795 c8b1aab4dfc58d17e9f00c358193899d 416 SMART SM00382 48 308 1.3E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0795 c8b1aab4dfc58d17e9f00c358193899d 416 Gene3D G3DSA:1.10.8.60 311 413 8.8E-30 T 11-10-2018 TO73_0104 2a53c80000b9dab7e4fd1162fce91820 140 SUPERFAMILY SSF51735 2 134 1.38E-39 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0104 2a53c80000b9dab7e4fd1162fce91820 140 Pfam PF13380 CoA binding domain 14 130 5.9E-36 T 11-10-2018 IPR003781 CoA-binding GO:0048037 TO73_0104 2a53c80000b9dab7e4fd1162fce91820 140 Gene3D G3DSA:3.40.50.720 1 140 6.6E-40 T 11-10-2018 TO73_0104 2a53c80000b9dab7e4fd1162fce91820 140 SMART SM00881 10 104 2.2E-14 T 11-10-2018 IPR003781 CoA-binding GO:0048037 TO73_2061 6dcfec7dd6f04f30ccf4ca3cb8457a55 440 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 268 419 9.5E-66 T 11-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain TO73_2061 6dcfec7dd6f04f30ccf4ca3cb8457a55 440 SUPERFAMILY SSF100950 187 429 6.12E-70 T 11-10-2018 IPR037171 NagB/RpiA transferase-like TO73_2061 6dcfec7dd6f04f30ccf4ca3cb8457a55 440 SUPERFAMILY SSF100950 3 219 3.81E-54 T 11-10-2018 IPR037171 NagB/RpiA transferase-like TO73_2061 6dcfec7dd6f04f30ccf4ca3cb8457a55 440 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 2 175 7.2E-27 T 11-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 TO73_2061 6dcfec7dd6f04f30ccf4ca3cb8457a55 440 Gene3D G3DSA:3.40.1080.10 1 179 1.9E-69 T 11-10-2018 TO73_2061 6dcfec7dd6f04f30ccf4ca3cb8457a55 440 Gene3D G3DSA:3.40.1080.20 287 428 3.5E-66 T 11-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily TO73_2061 6dcfec7dd6f04f30ccf4ca3cb8457a55 440 Gene3D G3DSA:3.30.750.70 183 285 7.5E-43 T 11-10-2018 TO73_0429 afea242bccee62a37acc0b69893e3230 99 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 47 1.2E-8 T 11-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0429 afea242bccee62a37acc0b69893e3230 99 SUPERFAMILY SSF63562 1 97 1.74E-20 T 11-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TO73_0429 afea242bccee62a37acc0b69893e3230 99 SMART SM01409 8 75 3.1E-7 T 11-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TO73_0429 afea242bccee62a37acc0b69893e3230 99 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 76 13.49 T 11-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TO73_0429 afea242bccee62a37acc0b69893e3230 99 Gene3D G3DSA:3.90.940.10 1 99 1.6E-62 T 11-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TO73_0429 afea242bccee62a37acc0b69893e3230 99 Pfam PF01192 RNA polymerase Rpb6 12 73 8.1E-7 T 11-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TO73_2291 13274d70e125db998a01aab192427e46 287 Pfam PF06267 Family of unknown function (DUF1028) 5 199 9.3E-77 T 11-10-2018 IPR010430 Protein of unknown function DUF1028 TO73_2291 13274d70e125db998a01aab192427e46 287 SUPERFAMILY SSF47090 212 254 3.92E-6 T 11-10-2018 IPR036365 PGBD-like superfamily TO73_2291 13274d70e125db998a01aab192427e46 287 Gene3D G3DSA:3.60.20.10 3 213 8.6E-81 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_2291 13274d70e125db998a01aab192427e46 287 Gene3D G3DSA:1.10.101.10 214 282 2.5E-6 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TO73_2291 13274d70e125db998a01aab192427e46 287 SUPERFAMILY SSF56235 5 216 1.62E-72 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_2291 13274d70e125db998a01aab192427e46 287 Pfam PF08823 Putative peptidoglycan binding domain 211 280 5.5E-20 T 11-10-2018 IPR014927 Putative peptidoglycan binding TO73_2372 e4684e3b1d0a1860eaf8dc241600772d 232 SUPERFAMILY SSF49344 1 193 2.9E-31 T 11-10-2018 TO73_2372 e4684e3b1d0a1860eaf8dc241600772d 232 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 3 111 8.8E-15 T 11-10-2018 IPR019248 Glucodextranase-like, C-terminal TO73_2372 e4684e3b1d0a1860eaf8dc241600772d 232 Gene3D G3DSA:2.60.40.1190 2 126 1.2E-13 T 11-10-2018 TO73_0928 18ffd5fd1c38bb55f5d311276997ce37 335 Gene3D G3DSA:3.40.47.10 176 329 1.2E-29 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0928 18ffd5fd1c38bb55f5d311276997ce37 335 SUPERFAMILY SSF53901 6 329 5.99E-27 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0928 18ffd5fd1c38bb55f5d311276997ce37 335 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 105 182 1.8E-10 T 11-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TO73_0928 18ffd5fd1c38bb55f5d311276997ce37 335 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 241 328 1.4E-16 T 11-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TO73_0928 18ffd5fd1c38bb55f5d311276997ce37 335 Gene3D G3DSA:3.40.47.10 1 173 5.5E-30 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 TO73_0592 fd60333338727881bbaa380c6b28328a 579 Pfam PF00005 ABC transporter 352 500 2.1E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0592 fd60333338727881bbaa380c6b28328a 579 SMART SM00382 361 562 2.8E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0592 fd60333338727881bbaa380c6b28328a 579 SUPERFAMILY SSF52540 332 571 7.88E-77 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0592 fd60333338727881bbaa380c6b28328a 579 Gene3D G3DSA:1.20.1560.10 1 322 1.5E-81 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TO73_0592 fd60333338727881bbaa380c6b28328a 579 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0592 fd60333338727881bbaa380c6b28328a 579 SUPERFAMILY SSF90123 10 325 2.35E-74 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TO73_0592 fd60333338727881bbaa380c6b28328a 579 Gene3D G3DSA:3.40.50.300 329 579 1.4E-78 T 11-10-2018 TO73_0592 fd60333338727881bbaa380c6b28328a 579 Pfam PF00664 ABC transporter transmembrane region 26 289 4.8E-51 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TO73_2083 c3c5d4390ef877eb2f959a814e706c0c 331 SUPERFAMILY SSF53850 20 316 2.68E-65 T 11-10-2018 TO73_2083 c3c5d4390ef877eb2f959a814e706c0c 331 PIRSF PIRSF002825 18 331 5.4E-78 T 11-10-2018 IPR026045 Ferric binding protein TO73_2083 c3c5d4390ef877eb2f959a814e706c0c 331 Pfam PF13416 Bacterial extracellular solute-binding protein 39 297 2.7E-21 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein TO73_2083 c3c5d4390ef877eb2f959a814e706c0c 331 Gene3D G3DSA:3.40.190.10 25 299 2.2E-114 T 11-10-2018 TO73_2083 c3c5d4390ef877eb2f959a814e706c0c 331 Gene3D G3DSA:3.40.190.10 119 313 2.2E-114 T 11-10-2018 TO73_1985 f4fe9b50991d05cf62982a5633cc4282 159 SMART SM00506 3 129 1.5E-34 T 11-10-2018 IPR002589 Macro domain TO73_1985 f4fe9b50991d05cf62982a5633cc4282 159 Pfam PF01661 Macro domain 20 129 8.2E-33 T 11-10-2018 IPR002589 Macro domain TO73_1985 f4fe9b50991d05cf62982a5633cc4282 159 SUPERFAMILY SSF52949 3 158 4.12E-47 T 11-10-2018 TO73_1985 f4fe9b50991d05cf62982a5633cc4282 159 Gene3D G3DSA:3.40.220.10 1 159 3.6E-62 T 11-10-2018 TO73_0187 69e5244bc43520cf3aedd36d1b951611 480 Pfam PF04233 Phage Mu protein F like protein 55 167 6.3E-21 T 11-10-2018 IPR006528 Phage head morphogenesis domain TO73_0187 69e5244bc43520cf3aedd36d1b951611 480 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 57 170 2.8E-18 T 11-10-2018 IPR006528 Phage head morphogenesis domain TO73_2044 186ff64b423c74a74f03f2f7c6292eb1 336 Pfam PF03739 Predicted permease YjgP/YjgQ family 4 334 4.6E-45 T 11-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 TO73_1319 f68218fde244af58f12ea3558f78b29a 175 SUPERFAMILY SSF63848 70 172 4.97E-29 T 11-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 TO73_1319 f68218fde244af58f12ea3558f78b29a 175 Gene3D G3DSA:2.160.20.70 68 175 3.9E-36 T 11-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 TO73_1319 f68218fde244af58f12ea3558f78b29a 175 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 73 170 1.1E-29 T 11-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 PIRSF PIRSF000460 1 718 1.4E-254 T 11-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 Pfam PF00343 Carbohydrate phosphorylase 263 609 7.5E-16 T 11-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 Pfam PF00343 Carbohydrate phosphorylase 117 166 7.6E-5 T 11-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 Gene3D G3DSA:3.40.50.2000 107 210 1.9E-10 T 11-10-2018 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 Gene3D G3DSA:3.40.50.2000 259 407 2.2E-12 T 11-10-2018 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 586 598 - T 11-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 Gene3D G3DSA:3.40.50.2000 408 648 5.8E-37 T 11-10-2018 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 101 691 4.1E-231 T 11-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 Pfam PF11897 Protein of unknown function (DUF3417) 13 113 1.7E-27 T 11-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TO73_1297 352d13b3ff4ad7e4e91ad853c0279897 818 SUPERFAMILY SSF53756 6 692 6.91E-189 T 11-10-2018 TO73_1509 5702647de0e90f092b2fb9e092c06f71 348 Gene3D G3DSA:3.30.2340.10 171 300 1.3E-89 T 11-10-2018 TO73_1509 5702647de0e90f092b2fb9e092c06f71 348 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 193 335 1.6E-26 T 11-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_1509 5702647de0e90f092b2fb9e092c06f71 348 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 14 171 2.3E-46 T 11-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_1509 5702647de0e90f092b2fb9e092c06f71 348 Gene3D G3DSA:3.30.2350.20 22 335 1.3E-89 T 11-10-2018 TO73_1509 5702647de0e90f092b2fb9e092c06f71 348 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 81 94 - T 11-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 TO73_1509 5702647de0e90f092b2fb9e092c06f71 348 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 9 340 26.458 T 11-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_1509 5702647de0e90f092b2fb9e092c06f71 348 SUPERFAMILY SSF55120 13 337 2.01E-87 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TO73_0331 8e9293eb3bc4a56ed8ede24f7c2f69c4 101 Pfam PF04134 Protein of unknown function, DUF393 1 100 5.2E-15 T 11-10-2018 IPR007263 Protein of unknown function DUF393 TO73_1558 3139494884906d7b5a0e1df61b7bd6dd 347 Pfam PF00155 Aminotransferase class I and II 23 338 4.8E-45 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TO73_1558 3139494884906d7b5a0e1df61b7bd6dd 347 Gene3D G3DSA:3.40.640.10 45 254 6.9E-88 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1558 3139494884906d7b5a0e1df61b7bd6dd 347 Gene3D G3DSA:3.90.1150.10 8 340 6.9E-88 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1558 3139494884906d7b5a0e1df61b7bd6dd 347 SUPERFAMILY SSF53383 14 340 2.99E-69 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1558 3139494884906d7b5a0e1df61b7bd6dd 347 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 204 213 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TO73_1558 3139494884906d7b5a0e1df61b7bd6dd 347 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 3 345 46.215 T 11-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TO73_0701 bc4775ec71bfb6e8ce54c0aeb9571025 288 Gene3D G3DSA:1.20.1510.10 1 199 5.0E-58 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TO73_0701 bc4775ec71bfb6e8ce54c0aeb9571025 288 Pfam PF16916 Dimerisation domain of Zinc Transporter 205 283 2.8E-23 T 11-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TO73_0701 bc4775ec71bfb6e8ce54c0aeb9571025 288 Gene3D G3DSA:3.30.70.1350 200 288 2.8E-34 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TO73_0701 bc4775ec71bfb6e8ce54c0aeb9571025 288 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 3 284 1.3E-73 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TO73_0701 bc4775ec71bfb6e8ce54c0aeb9571025 288 SUPERFAMILY SSF161111 2 202 1.1E-56 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TO73_0701 bc4775ec71bfb6e8ce54c0aeb9571025 288 SUPERFAMILY SSF160240 204 283 2.22E-22 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TO73_0701 bc4775ec71bfb6e8ce54c0aeb9571025 288 Pfam PF01545 Cation efflux family 7 200 2.8E-44 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TO73_0699 f3d784d30984886cddaa5129338f8d22 142 Pfam PF02310 B12 binding domain 8 123 2.3E-24 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TO73_0699 f3d784d30984886cddaa5129338f8d22 142 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 134 1.9E-51 T 11-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TO73_0699 f3d784d30984886cddaa5129338f8d22 142 Gene3D G3DSA:3.40.50.280 1 140 2.0E-61 T 11-10-2018 TO73_0699 f3d784d30984886cddaa5129338f8d22 142 SUPERFAMILY SSF52242 3 134 1.02E-50 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TO73_1635 138bdbf77749cc43c01478e7b33daec3 191 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 5 188 37.342 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_1635 138bdbf77749cc43c01478e7b33daec3 191 ProSitePatterns PS01236 PdxT/SNO family family signature. 42 52 - T 11-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_1635 138bdbf77749cc43c01478e7b33daec3 191 SUPERFAMILY SSF52317 4 188 1.19E-46 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1635 138bdbf77749cc43c01478e7b33daec3 191 Pfam PF01174 SNO glutamine amidotransferase family 7 187 1.2E-59 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_1635 138bdbf77749cc43c01478e7b33daec3 191 Gene3D G3DSA:3.40.50.880 2 190 2.0E-65 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1635 138bdbf77749cc43c01478e7b33daec3 191 PIRSF PIRSF005639 1 190 3.1E-67 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_1635 138bdbf77749cc43c01478e7b33daec3 191 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 5 187 7.2E-67 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_0134 d2f52a40b176cef85b2e80dd813364f3 115 Pfam PF11255 Protein of unknown function (DUF3054) 5 108 1.4E-15 T 11-10-2018 IPR021414 Protein of unknown function DUF3054 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 Pfam PF00152 tRNA synthetases class II (D, K and N) 106 416 5.4E-77 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 Gene3D G3DSA:3.30.930.10 93 411 2.5E-118 T 11-10-2018 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 SUPERFAMILY SSF55681 95 421 4.23E-78 T 11-10-2018 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 422 38.887 T 11-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 SUPERFAMILY SSF50249 4 93 2.36E-21 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 Pfam PF01336 OB-fold nucleic acid binding domain 17 85 7.7E-7 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 Gene3D G3DSA:2.40.50.140 1 92 7.7E-25 T 11-10-2018 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 9 422 4.8E-118 T 11-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 204 9.4E-22 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 377 391 9.4E-22 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 337 353 9.4E-22 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1534 5618c06844a1d1c1bcf52029976c41dd 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 175 187 9.4E-22 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_0314 96cad35843cc60605ed6625b867b6474 342 Gene3D G3DSA:1.20.1250.20 2 177 3.2E-13 T 11-10-2018 TO73_0314 96cad35843cc60605ed6625b867b6474 342 Gene3D G3DSA:1.20.1250.20 178 338 4.1E-14 T 11-10-2018 TO73_0314 96cad35843cc60605ed6625b867b6474 342 Pfam PF07690 Major Facilitator Superfamily 8 296 1.1E-14 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TO73_0314 96cad35843cc60605ed6625b867b6474 342 SUPERFAMILY SSF103473 2 334 6.93E-24 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_0653 cb2fb66a67b76006821af8c44a6638ce 82 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.667 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TO73_0653 cb2fb66a67b76006821af8c44a6638ce 82 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 66 3.0E-20 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TO73_0653 cb2fb66a67b76006821af8c44a6638ce 82 SMART SM01234 1 68 7.1E-43 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TO73_0653 cb2fb66a67b76006821af8c44a6638ce 82 Pfam PF01809 Haemolytic domain 4 68 4.5E-29 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TO73_0653 cb2fb66a67b76006821af8c44a6638ce 82 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 72 4.2E-30 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TO73_1220 0564a7acb158ca5e40e44dea8ccb9d58 144 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 144 46.225 T 11-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TO73_1220 0564a7acb158ca5e40e44dea8ccb9d58 144 SUPERFAMILY SSF89447 1 132 8.97E-44 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily TO73_1220 0564a7acb158ca5e40e44dea8ccb9d58 144 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 139 2.0E-64 T 11-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TO73_1220 0564a7acb158ca5e40e44dea8ccb9d58 144 Pfam PF02381 MraZ protein, putative antitoxin-like 72 131 9.6E-12 T 11-10-2018 IPR020603 MraZ domain TO73_1220 0564a7acb158ca5e40e44dea8ccb9d58 144 Pfam PF02381 MraZ protein, putative antitoxin-like 4 70 1.6E-18 T 11-10-2018 IPR020603 MraZ domain TO73_1220 0564a7acb158ca5e40e44dea8ccb9d58 144 Gene3D G3DSA:2.40.330.20 1 137 1.9E-42 T 11-10-2018 IPR038619 MraZ superfamily TO73_1220 0564a7acb158ca5e40e44dea8ccb9d58 144 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 128 4.3E-35 T 11-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TO73_0665 d0beffd733c80c1f8366f3bcdc665411 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 6 59 5.3E-25 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0665 d0beffd733c80c1f8366f3bcdc665411 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 58 20.035 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0665 d0beffd733c80c1f8366f3bcdc665411 60 Pfam PF01783 Ribosomal L32p protein family 5 59 3.2E-26 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0665 d0beffd733c80c1f8366f3bcdc665411 60 SUPERFAMILY SSF57829 5 60 2.38E-21 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TO73_1950 e2ceace473c6408e842d820cefbc65e7 377 Pfam PF00999 Sodium/hydrogen exchanger family 14 351 5.2E-33 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TO73_1950 e2ceace473c6408e842d820cefbc65e7 377 Gene3D G3DSA:1.20.1530.20 4 359 5.9E-41 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily TO73_0552 a1910e6f25c06023b13197113d3662a4 184 PRINTS PR01100 Shikimate kinase family signature 65 73 1.5E-16 T 11-10-2018 TO73_0552 a1910e6f25c06023b13197113d3662a4 184 PRINTS PR01100 Shikimate kinase family signature 37 50 1.5E-16 T 11-10-2018 TO73_0552 a1910e6f25c06023b13197113d3662a4 184 PRINTS PR01100 Shikimate kinase family signature 104 121 1.5E-16 T 11-10-2018 TO73_0552 a1910e6f25c06023b13197113d3662a4 184 PRINTS PR01100 Shikimate kinase family signature 83 92 1.5E-16 T 11-10-2018 TO73_0552 a1910e6f25c06023b13197113d3662a4 184 PRINTS PR01100 Shikimate kinase family signature 13 28 1.5E-16 T 11-10-2018 TO73_0552 a1910e6f25c06023b13197113d3662a4 184 ProSitePatterns PS01128 Shikimate kinase signature. 66 91 - T 11-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TO73_0552 a1910e6f25c06023b13197113d3662a4 184 Gene3D G3DSA:3.40.50.300 12 182 9.5E-53 T 11-10-2018 TO73_0552 a1910e6f25c06023b13197113d3662a4 184 Hamap MF_00109 Shikimate kinase [aroK]. 10 176 27.883 T 11-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TO73_0552 a1910e6f25c06023b13197113d3662a4 184 SUPERFAMILY SSF52540 11 174 3.46E-26 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0552 a1910e6f25c06023b13197113d3662a4 184 Pfam PF01202 Shikimate kinase 19 175 4.9E-45 T 11-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TO73_1030 eb749c30e7cafa8154beff855fb4e025 554 SUPERFAMILY SSF52540 221 406 6.62E-7 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1030 eb749c30e7cafa8154beff855fb4e025 554 Pfam PF09818 Predicted ATPase of the ABC class 7 434 2.0E-156 T 11-10-2018 IPR019195 ABC transporter, ATPase, putative TO73_1645 0629abc8fb2dfcd78d56042b52eed72b 237 SUPERFAMILY SSF53335 63 224 8.36E-24 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1645 0629abc8fb2dfcd78d56042b52eed72b 237 Pfam PF08241 Methyltransferase domain 103 189 2.0E-14 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TO73_1645 0629abc8fb2dfcd78d56042b52eed72b 237 Gene3D G3DSA:3.40.50.150 58 226 2.9E-24 T 11-10-2018 TO73_0694 ad0907c7e7726d907c7820b98ef97720 194 Gene3D G3DSA:2.40.30.20 1 86 6.8E-23 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_0694 ad0907c7e7726d907c7820b98ef97720 194 PIRSF PIRSF000498 1 194 4.0E-67 T 11-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0694 ad0907c7e7726d907c7820b98ef97720 194 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 193 2.7E-58 T 11-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0694 ad0907c7e7726d907c7820b98ef97720 194 SUPERFAMILY SSF63380 1 90 1.87E-20 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TO73_0694 ad0907c7e7726d907c7820b98ef97720 194 Pfam PF00677 Lumazine binding domain 97 181 6.4E-24 T 11-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0694 ad0907c7e7726d907c7820b98ef97720 194 Pfam PF00677 Lumazine binding domain 3 84 2.0E-16 T 11-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TO73_0694 ad0907c7e7726d907c7820b98ef97720 194 Gene3D G3DSA:2.40.30.20 99 194 4.9E-32 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TO73_0694 ad0907c7e7726d907c7820b98ef97720 194 SUPERFAMILY SSF63380 90 192 7.82E-33 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TO73_1489 839bf9a5980024d71d85ca95d0a3819c 43 Pfam PF03779 SPW repeat 10 41 2.6E-8 T 11-10-2018 IPR005530 SPW repeat TO73_2519 e08d5076491e3fa6020e1bc3bffd924b 83 SUPERFAMILY SSF143880 6 77 1.44E-17 T 11-10-2018 IPR036782 NE0471-like, N-terminal TO73_2519 e08d5076491e3fa6020e1bc3bffd924b 83 Gene3D G3DSA:3.30.2020.10 2 78 4.7E-8 T 11-10-2018 IPR036782 NE0471-like, N-terminal TO73_2519 e08d5076491e3fa6020e1bc3bffd924b 83 Pfam PF10387 Protein of unknown function (DUF2442) 9 79 1.6E-16 T 11-10-2018 IPR018841 Protein of unknown function DUF2442 TO73_0115 8d94cef0306b773f2b70ae360bbefe12 107 Gene3D G3DSA:1.10.287.1080 2 107 1.4E-29 T 11-10-2018 TO73_0115 8d94cef0306b773f2b70ae360bbefe12 107 PIRSF PIRSF029904 1 107 5.6E-42 T 11-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD TO73_0115 8d94cef0306b773f2b70ae360bbefe12 107 SUPERFAMILY SSF101386 2 101 7.61E-25 T 11-10-2018 TO73_0115 8d94cef0306b773f2b70ae360bbefe12 107 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 101 2.8E-17 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TO73_2825 97943a04be22ba49f009523fa17898b1 205 Pfam PF10099 Anti-sigma-K factor rskA 42 200 3.0E-15 T 11-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 TO73_2825 97943a04be22ba49f009523fa17898b1 205 Gene3D G3DSA:1.10.10.1320 2 73 1.2E-8 T 11-10-2018 TO73_2825 97943a04be22ba49f009523fa17898b1 205 Pfam PF13490 Putative zinc-finger 4 31 5.7E-6 T 11-10-2018 IPR027383 Putative zinc-finger TO73_0144 73863db276575cf9c4f4f2662f437fbd 348 Pfam PF00483 Nucleotidyl transferase 2 230 1.1E-48 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TO73_0144 73863db276575cf9c4f4f2662f437fbd 348 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 347 8.2E-133 T 11-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form TO73_0144 73863db276575cf9c4f4f2662f437fbd 348 Gene3D G3DSA:2.160.10.10 238 310 2.5E-7 T 11-10-2018 TO73_0144 73863db276575cf9c4f4f2662f437fbd 348 SUPERFAMILY SSF53448 1 280 1.35E-73 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0144 73863db276575cf9c4f4f2662f437fbd 348 Gene3D G3DSA:3.90.550.10 1 237 3.8E-71 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0980 f844186ab9142e90c586a4d8fb325ff0 318 Pfam PF05107 CRISPR-associated protein Cas7 4 239 4.9E-50 T 11-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C TO73_0980 f844186ab9142e90c586a4d8fb325ff0 318 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 4 241 1.1E-48 T 11-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C TO73_0980 f844186ab9142e90c586a4d8fb325ff0 318 TIGRFAM TIGR02590 cas_Csh2: CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI 4 303 1.1E-57 T 11-10-2018 IPR013419 CRISPR-associated protein Csh2 TO73_0865 b8b92d1303c4dfba4c51f71a97293886 172 Gene3D G3DSA:3.40.50.1240 1 171 8.1E-54 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_0865 b8b92d1303c4dfba4c51f71a97293886 172 PIRSF PIRSF000709 2 143 1.4E-6 T 11-10-2018 TO73_0865 b8b92d1303c4dfba4c51f71a97293886 172 SUPERFAMILY SSF53254 2 159 3.14E-48 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_0865 b8b92d1303c4dfba4c51f71a97293886 172 SMART SM00855 2 140 4.6E-27 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TO73_0865 b8b92d1303c4dfba4c51f71a97293886 172 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 11-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 TO73_0865 b8b92d1303c4dfba4c51f71a97293886 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 144 2.9E-37 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TO73_1428 62c70158ed84bc6db92a23757ff97677 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 3 178 3.6E-39 T 11-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TO73_1428 62c70158ed84bc6db92a23757ff97677 201 Pfam PF00694 Aconitase C-terminal domain 3 121 1.7E-18 T 11-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TO73_1428 62c70158ed84bc6db92a23757ff97677 201 SUPERFAMILY SSF52016 3 190 4.32E-47 T 11-10-2018 TO73_1428 62c70158ed84bc6db92a23757ff97677 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 2 197 35.038 T 11-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TO73_1428 62c70158ed84bc6db92a23757ff97677 201 Gene3D G3DSA:3.20.19.10 1 178 2.6E-56 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TO73_1882 59a347bec0e5f570be7c85d7438862fe 284 Pfam PF03060 Nitronate monooxygenase 3 232 3.0E-30 T 11-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 TO73_1882 59a347bec0e5f570be7c85d7438862fe 284 SUPERFAMILY SSF51412 1 280 5.65E-53 T 11-10-2018 TO73_1882 59a347bec0e5f570be7c85d7438862fe 284 Gene3D G3DSA:3.20.20.70 1 283 5.3E-74 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0715 e3d8e78ca26e26ac0f414799d0173897 94 Pfam PF02033 Ribosome-binding factor A 7 88 2.1E-12 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TO73_0715 e3d8e78ca26e26ac0f414799d0173897 94 SUPERFAMILY SSF89919 7 89 2.35E-17 T 11-10-2018 IPR023799 Ribosome-binding factor A domain superfamily TO73_0715 e3d8e78ca26e26ac0f414799d0173897 94 Gene3D G3DSA:3.30.300.20 1 92 2.6E-20 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_0715 e3d8e78ca26e26ac0f414799d0173897 94 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 90 17.218 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TO73_0446 28cd88399af685d2f9d700fdfb8fcfd4 75 Pfam PF04255 Protein of unknown function (DUF433) 7 62 3.5E-22 T 11-10-2018 IPR007367 Protein of unknown function DUF433 TO73_0446 28cd88399af685d2f9d700fdfb8fcfd4 75 SUPERFAMILY SSF46689 2 72 1.67E-22 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_0446 28cd88399af685d2f9d700fdfb8fcfd4 75 Gene3D G3DSA:1.10.10.10 6 74 1.7E-17 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1553 cbf3638bde6cd2dd0acffeae40ca6d7d 396 Pfam PF00155 Aminotransferase class I and II 51 385 2.9E-41 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TO73_1553 cbf3638bde6cd2dd0acffeae40ca6d7d 396 Gene3D G3DSA:3.40.640.10 69 284 7.9E-151 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1553 cbf3638bde6cd2dd0acffeae40ca6d7d 396 Gene3D G3DSA:3.90.1150.10 22 389 7.9E-151 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1553 cbf3638bde6cd2dd0acffeae40ca6d7d 396 SUPERFAMILY SSF53383 9 391 3.48E-100 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_0016 ec29d5cfbc57f600dc5720bb9d60a6b5 249 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 234 6.6E-66 T 11-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TO73_0016 ec29d5cfbc57f600dc5720bb9d60a6b5 249 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 249 36.112 T 11-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TO73_0016 ec29d5cfbc57f600dc5720bb9d60a6b5 249 Gene3D G3DSA:3.40.1210.10 1 244 4.4E-86 T 11-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TO73_0016 ec29d5cfbc57f600dc5720bb9d60a6b5 249 SUPERFAMILY SSF64167 1 247 1.96E-80 T 11-10-2018 TO73_0016 ec29d5cfbc57f600dc5720bb9d60a6b5 249 Pfam PF01975 Survival protein SurE 3 185 2.8E-54 T 11-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TO73_1434 81e96d103166b236ad1a5276dc043f95 126 SUPERFAMILY SSF46626 12 110 2.58E-17 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_1434 81e96d103166b236ad1a5276dc043f95 126 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 19 94 4.9E-9 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_1434 81e96d103166b236ad1a5276dc043f95 126 Gene3D G3DSA:1.10.760.10 12 124 1.1E-17 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_1937 9e14cd37ee306ec5884e65bdc7fd0af6 69 Pfam PF13586 Transposase DDE domain 11 62 2.1E-12 T 11-10-2018 IPR025668 Transposase DDE domain TO73_1917 9e14cd37ee306ec5884e65bdc7fd0af6 69 Pfam PF13586 Transposase DDE domain 11 62 2.1E-12 T 11-10-2018 IPR025668 Transposase DDE domain TO73_2821 902404b46cbe81378671de355c910231 231 SUPERFAMILY SSF53098 4 223 8.34E-12 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2821 902404b46cbe81378671de355c910231 231 Pfam PF01609 Transposase DDE domain 42 229 2.9E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_0588 9efa0b3fd0aacff3133c224e11306fa8 404 Gene3D G3DSA:3.40.50.150 70 397 3.0E-54 T 11-10-2018 TO73_0588 9efa0b3fd0aacff3133c224e11306fa8 404 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 334 365 - T 11-10-2018 IPR030390 RNA methyltransferase TrmA, active site TO73_0588 9efa0b3fd0aacff3133c224e11306fa8 404 Gene3D G3DSA:3.40.1350.30 110 242 3.0E-54 T 11-10-2018 TO73_0588 9efa0b3fd0aacff3133c224e11306fa8 404 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 239 400 1.2E-17 T 11-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TO73_0588 9efa0b3fd0aacff3133c224e11306fa8 404 Gene3D G3DSA:2.40.50.140 1 64 4.4E-5 T 11-10-2018 TO73_0588 9efa0b3fd0aacff3133c224e11306fa8 404 SUPERFAMILY SSF53335 72 400 4.98E-47 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2809 ffae84ed5c2ce7928240b57c4e3ea1d3 416 ProSitePatterns PS01007 Transposases, Mutator family, signature. 213 237 - T 11-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TO73_2809 ffae84ed5c2ce7928240b57c4e3ea1d3 416 Pfam PF00872 Transposase, Mutator family 4 359 3.4E-91 T 11-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TO73_0706 a3be19a149f3235e6296b43609cc438f 138 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 138 16.554 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TO73_0706 a3be19a149f3235e6296b43609cc438f 138 SUPERFAMILY SSF55486 13 137 2.3E-33 T 11-10-2018 TO73_0706 a3be19a149f3235e6296b43609cc438f 138 Pfam PF02130 Uncharacterized protein family UPF0054 19 137 3.3E-30 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TO73_0706 a3be19a149f3235e6296b43609cc438f 138 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 34 137 2.0E-26 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TO73_0706 a3be19a149f3235e6296b43609cc438f 138 Gene3D G3DSA:3.40.390.30 2 138 6.9E-35 T 11-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 TO73_0510 65c115fb73a0abd002fb9e14da041454 203 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 27 122 7.0E-13 T 11-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TO73_0510 65c115fb73a0abd002fb9e14da041454 203 SUPERFAMILY SSF63999 4 122 2.49E-24 T 11-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TO73_0510 65c115fb73a0abd002fb9e14da041454 203 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 196 3.3E-40 T 11-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TO73_0510 65c115fb73a0abd002fb9e14da041454 203 Gene3D G3DSA:3.40.50.10240 3 201 2.9E-35 T 11-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TO73_1301 3e0d0a3f0d8981f1c2ff63b95c4994f2 287 Pfam PF13413 Helix-turn-helix domain 7 68 6.6E-22 T 11-10-2018 TO73_1301 3e0d0a3f0d8981f1c2ff63b95c4994f2 287 Pfam PF13464 Domain of unknown function (DUF4115) 217 282 2.3E-12 T 11-10-2018 IPR025194 Domain of unknown function DUF4115 TO73_1301 3e0d0a3f0d8981f1c2ff63b95c4994f2 287 Gene3D G3DSA:1.10.260.40 1 87 1.4E-25 T 11-10-2018 TO73_1301 3e0d0a3f0d8981f1c2ff63b95c4994f2 287 SUPERFAMILY SSF47413 3 72 2.78E-6 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TO73_1301 3e0d0a3f0d8981f1c2ff63b95c4994f2 287 Pfam PF08308 PEGA domain 136 193 2.4E-16 T 11-10-2018 IPR013229 PEGA TO73_0218 f47b8adb58b0dfcb24816a4e0ff2b5f7 185 SMART SM00471 18 141 2.4E-8 T 11-10-2018 IPR003607 HD/PDEase domain TO73_0218 f47b8adb58b0dfcb24816a4e0ff2b5f7 185 SUPERFAMILY SSF109604 12 176 5.89E-25 T 11-10-2018 TO73_0218 f47b8adb58b0dfcb24816a4e0ff2b5f7 185 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 15 178 1.2E-32 T 11-10-2018 IPR005249 Conserved hypothetical protein CHP00488 TO73_0218 f47b8adb58b0dfcb24816a4e0ff2b5f7 185 Gene3D G3DSA:1.10.3210.10 2 183 5.8E-41 T 11-10-2018 TO73_0218 f47b8adb58b0dfcb24816a4e0ff2b5f7 185 Pfam PF01966 HD domain 22 114 6.9E-12 T 11-10-2018 IPR006674 HD domain TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 PRINTS PR00415 Aconitase family signature 380 394 3.0E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 PRINTS PR00415 Aconitase family signature 299 312 3.0E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 PRINTS PR00415 Aconitase family signature 223 238 3.0E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 PRINTS PR00415 Aconitase family signature 507 520 3.0E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 PRINTS PR00415 Aconitase family signature 152 165 3.0E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 PRINTS PR00415 Aconitase family signature 285 298 3.0E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 PRINTS PR00415 Aconitase family signature 445 456 3.0E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 PRINTS PR00415 Aconitase family signature 176 184 3.0E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 PRINTS PR00415 Aconitase family signature 209 222 3.0E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 24 903 0.0 T 11-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 Pfam PF00330 Aconitase family (aconitate hydratase) 85 576 4.3E-181 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 ProSitePatterns PS00450 Aconitase family signature 1. 441 457 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 Gene3D G3DSA:3.30.499.10 381 604 5.0E-106 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 SUPERFAMILY SSF52016 645 902 6.08E-84 T 11-10-2018 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 Gene3D G3DSA:3.20.19.10 666 904 1.0E-102 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 Gene3D G3DSA:1.10.1440.20 605 665 1.5E-23 T 11-10-2018 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 Gene3D G3DSA:3.30.499.20 11 380 5.9E-159 T 11-10-2018 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 SUPERFAMILY SSF53732 11 640 5.23E-230 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TO73_1591 923725c8ba19ad4ec0d58a72874da0ef 909 Pfam PF00694 Aconitase C-terminal domain 704 830 2.3E-44 T 11-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TO73_2834 d9779c4871937278f53633f20631d420 323 Gene3D G3DSA:1.10.620.20 2 294 1.7E-43 T 11-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 TO73_2834 d9779c4871937278f53633f20631d420 323 SUPERFAMILY SSF47240 9 318 2.11E-48 T 11-10-2018 IPR009078 Ferritin-like superfamily TO73_2834 d9779c4871937278f53633f20631d420 323 Pfam PF00268 Ribonucleotide reductase, small chain 9 279 3.0E-32 T 11-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TO73_1589 f01cfca9285ab2efd8363b568626fc87 426 Pfam PF00361 Proton-conducting membrane transporter 102 373 7.7E-57 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1589 f01cfca9285ab2efd8363b568626fc87 426 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 14 420 15.898 T 11-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 TO73_1348 0c1ee6c0bfe27a14ecbb1ac132b03f18 221 SUPERFAMILY SSF53167 28 199 2.23E-23 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TO73_1348 0c1ee6c0bfe27a14ecbb1ac132b03f18 221 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 3 212 4.1E-57 T 11-10-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 TO73_1348 0c1ee6c0bfe27a14ecbb1ac132b03f18 221 Pfam PF01048 Phosphorylase superfamily 28 210 7.3E-18 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TO73_1348 0c1ee6c0bfe27a14ecbb1ac132b03f18 221 Gene3D G3DSA:3.40.50.1580 23 217 5.6E-28 T 11-10-2018 TO73_1348 0c1ee6c0bfe27a14ecbb1ac132b03f18 221 Hamap MF_00991 Futalosine hydrolase [mqnB]. 4 216 23.302 T 11-10-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 TO73_0627 718928c028b8712b367587f50c5078b6 520 Pfam PF01274 Malate synthase 15 519 6.3E-201 T 11-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TO73_0627 718928c028b8712b367587f50c5078b6 520 ProSitePatterns PS00510 Malate synthase signature. 258 273 - T 11-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TO73_0627 718928c028b8712b367587f50c5078b6 520 Gene3D G3DSA:3.20.20.360 5 402 2.5E-190 T 11-10-2018 TO73_0627 718928c028b8712b367587f50c5078b6 520 Gene3D G3DSA:1.20.1220.12 405 519 5.8E-43 T 11-10-2018 TO73_0627 718928c028b8712b367587f50c5078b6 520 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 16 519 1.2E-237 T 11-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TO73_0627 718928c028b8712b367587f50c5078b6 520 PIRSF PIRSF001363 1 520 1.5E-247 T 11-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TO73_0627 718928c028b8712b367587f50c5078b6 520 SUPERFAMILY SSF51645 15 519 4.19E-188 T 11-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TO73_0936 7094ce954ca4233548745653327026bb 241 Gene3D G3DSA:3.40.50.300 2 240 2.0E-62 T 11-10-2018 TO73_0936 7094ce954ca4233548745653327026bb 241 SMART SM00382 29 216 3.1E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0936 7094ce954ca4233548745653327026bb 241 SUPERFAMILY SSF52540 4 237 3.41E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0936 7094ce954ca4233548745653327026bb 241 Pfam PF00005 ABC transporter 20 167 4.5E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0936 7094ce954ca4233548745653327026bb 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 216 238 1.3E-7 T 11-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TO73_1024 5c027b3d89f497ae940cde8e8593870a 640 SUPERFAMILY SSF52833 3 126 1.38E-32 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1024 5c027b3d89f497ae940cde8e8593870a 640 PIRSF PIRSF006402 1 580 3.4E-190 T 11-10-2018 IPR024705 Spermatogenesis-associated protein 20 TO73_1024 5c027b3d89f497ae940cde8e8593870a 640 Gene3D G3DSA:3.40.30.10 1 167 1.6E-67 T 11-10-2018 TO73_1024 5c027b3d89f497ae940cde8e8593870a 640 SUPERFAMILY SSF48208 185 497 6.8E-54 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TO73_1024 5c027b3d89f497ae940cde8e8593870a 640 Pfam PF03190 Protein of unknown function, DUF255 2 162 1.8E-72 T 11-10-2018 IPR004879 Domain of unknown function DUF255 TO73_1145 2fdd42b4cd9a87186b44509d5fabb473 109 SUPERFAMILY SSF54913 1 109 3.34E-15 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TO73_1145 2fdd42b4cd9a87186b44509d5fabb473 109 Gene3D G3DSA:3.30.70.120 1 103 1.8E-38 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TO73_1145 2fdd42b4cd9a87186b44509d5fabb473 109 Pfam PF06153 Cyclic-di-AMP receptor 1 108 6.8E-48 T 11-10-2018 IPR010375 Cyclic-di-AMP receptor TO73_0793 2ec12a26aeba359c432fcb9b39937233 462 Pfam PF00158 Sigma-54 interaction domain 168 225 1.2E-4 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TO73_0793 2ec12a26aeba359c432fcb9b39937233 462 SUPERFAMILY SSF52540 41 376 9.12E-21 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0793 2ec12a26aeba359c432fcb9b39937233 462 Gene3D G3DSA:3.40.50.300 39 249 1.7E-26 T 11-10-2018 TO73_1911 2a9467d8c3f17944b3bef824a1faf863 286 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 6 277 1.4E-82 T 11-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 TO73_1911 2a9467d8c3f17944b3bef824a1faf863 286 Pfam PF03787 RAMP superfamily 8 276 9.8E-27 T 11-10-2018 IPR005537 CRISPR type III-associated RAMP protein TO73_2858 5b00852828929183dad17eb0b24e4c3b 180 SUPERFAMILY SSF143100 20 80 2.88E-9 T 11-10-2018 IPR035069 TTHA1013/TTHA0281-like TO73_2858 5b00852828929183dad17eb0b24e4c3b 180 Gene3D G3DSA:1.10.260.40 104 169 2.1E-10 T 11-10-2018 TO73_2858 5b00852828929183dad17eb0b24e4c3b 180 Gene3D G3DSA:3.30.160.250 18 99 8.1E-8 T 11-10-2018 TO73_2858 5b00852828929183dad17eb0b24e4c3b 180 SUPERFAMILY SSF47413 109 173 1.2E-8 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TO73_2168 220fc676bb98d4adf77e40cd81c79919 476 SUPERFAMILY SSF103365 3 476 1.19E-161 T 11-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TO73_2168 220fc676bb98d4adf77e40cd81c79919 476 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 45 74 - T 11-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TO73_2168 220fc676bb98d4adf77e40cd81c79919 476 Gene3D G3DSA:3.90.1860.10 1 476 5.4E-185 T 11-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TO73_2168 220fc676bb98d4adf77e40cd81c79919 476 Pfam PF01139 tRNA-splicing ligase RtcB 45 476 3.5E-156 T 11-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TO73_1344 5d4482e455af74173544aafee2080d46 323 Gene3D G3DSA:3.50.50.60 135 252 4.5E-54 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1344 5d4482e455af74173544aafee2080d46 323 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 290 4.2E-67 T 11-10-2018 TO73_1344 5d4482e455af74173544aafee2080d46 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 3.4E-22 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_1344 5d4482e455af74173544aafee2080d46 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.4E-22 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_1344 5d4482e455af74173544aafee2080d46 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 3.4E-22 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_1344 5d4482e455af74173544aafee2080d46 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 131 3.4E-22 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TO73_1344 5d4482e455af74173544aafee2080d46 323 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 3 319 2.3E-115 T 11-10-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA TO73_1344 5d4482e455af74173544aafee2080d46 323 SUPERFAMILY SSF51905 1 319 1.87E-44 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1344 5d4482e455af74173544aafee2080d46 323 Gene3D G3DSA:3.50.50.60 3 296 4.5E-54 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1344 5d4482e455af74173544aafee2080d46 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 1.6E-17 T 11-10-2018 TO73_1344 5d4482e455af74173544aafee2080d46 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 1.6E-17 T 11-10-2018 TO73_1344 5d4482e455af74173544aafee2080d46 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.6E-17 T 11-10-2018 TO73_1344 5d4482e455af74173544aafee2080d46 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 261 1.6E-17 T 11-10-2018 TO73_0305 c01ff2df00bc2e7493e5550a1ac797d8 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 268 2.3E-10 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0305 c01ff2df00bc2e7493e5550a1ac797d8 279 SUPERFAMILY SSF161098 48 266 1.83E-49 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0305 c01ff2df00bc2e7493e5550a1ac797d8 279 Gene3D G3DSA:1.10.3720.10 46 278 4.0E-60 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 243 3.5E-66 T 11-10-2018 TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 3.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 4 242 1.9E-99 T 11-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 SUPERFAMILY SSF51735 2 243 1.1E-83 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 183 1.3E-4 T 11-10-2018 TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 Gene3D G3DSA:3.40.50.720 1 245 4.2E-85 T 11-10-2018 TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.6E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 4.6E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0662 cab40c34a5ce054f03a78021dfcd42c0 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 4.6E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1971 76082a65994405f4d7ff0b2ccee8755c 119 Pfam PF13586 Transposase DDE domain 61 112 2.1E-10 T 11-10-2018 IPR025668 Transposase DDE domain TO73_0358 37dfcb38bb26c51a447788e426486ffb 340 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 10 307 1.6E-90 T 11-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TO73_0358 37dfcb38bb26c51a447788e426486ffb 340 Pfam PF02401 LytB protein 10 305 6.0E-80 T 11-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TO73_0358 37dfcb38bb26c51a447788e426486ffb 340 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 8 309 34.277 T 11-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TO73_0358 37dfcb38bb26c51a447788e426486ffb 340 Gene3D G3DSA:3.40.1010.20 113 219 1.8E-95 T 11-10-2018 TO73_0358 37dfcb38bb26c51a447788e426486ffb 340 Gene3D G3DSA:3.40.50.11270 19 112 1.8E-95 T 11-10-2018 TO73_0358 37dfcb38bb26c51a447788e426486ffb 340 Gene3D G3DSA:3.40.1010.20 14 304 1.8E-95 T 11-10-2018 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 PRINTS PR00783 Major intrinsic protein family signature 120 138 3.4E-39 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 PRINTS PR00783 Major intrinsic protein family signature 148 170 3.4E-39 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 PRINTS PR00783 Major intrinsic protein family signature 40 64 3.4E-39 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 PRINTS PR00783 Major intrinsic protein family signature 185 205 3.4E-39 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 PRINTS PR00783 Major intrinsic protein family signature 7 26 3.4E-39 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 PRINTS PR00783 Major intrinsic protein family signature 77 96 3.4E-39 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 Pfam PF00230 Major intrinsic protein 4 198 2.2E-33 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 Gene3D G3DSA:1.20.1080.10 1 210 2.4E-49 T 11-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 SUPERFAMILY SSF81338 3 205 4.06E-48 T 11-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TO73_0951 138b5f12a5ec062a7e4233063bfcfecd 211 ProSitePatterns PS00221 MIP family signature. 58 66 - T 11-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 TO73_1628 44328f9b945cc055ed9aca91dfdc5fb8 332 SUPERFAMILY SSF50331 218 330 1.4E-10 T 11-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TO73_1628 44328f9b945cc055ed9aca91dfdc5fb8 332 SUPERFAMILY SSF52540 20 223 2.17E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1628 44328f9b945cc055ed9aca91dfdc5fb8 332 Pfam PF00005 ABC transporter 26 143 5.5E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1628 44328f9b945cc055ed9aca91dfdc5fb8 332 SMART SM00382 22 191 7.5E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1628 44328f9b945cc055ed9aca91dfdc5fb8 332 Gene3D G3DSA:3.40.50.300 4 220 1.1E-56 T 11-10-2018 TO73_1628 44328f9b945cc055ed9aca91dfdc5fb8 332 ProSitePatterns PS00211 ABC transporters family signature. 115 129 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0891 803480922e864e7d7626569b933b5167 454 Gene3D G3DSA:1.10.3720.10 197 441 6.3E-57 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0891 803480922e864e7d7626569b933b5167 454 SUPERFAMILY SSF161098 8 68 5.36E-5 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0891 803480922e864e7d7626569b933b5167 454 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 256 447 7.5E-17 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0891 803480922e864e7d7626569b933b5167 454 SUPERFAMILY SSF161098 208 453 4.58E-62 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0474 bf688c5172abd9151dc3ee3c178706f0 105 Gene3D G3DSA:3.30.428.10 1 105 8.9E-38 T 11-10-2018 IPR036265 HIT-like superfamily TO73_0474 bf688c5172abd9151dc3ee3c178706f0 105 Pfam PF01230 HIT domain 11 105 1.0E-24 T 11-10-2018 IPR001310 Histidine triad (HIT) protein TO73_0474 bf688c5172abd9151dc3ee3c178706f0 105 PRINTS PR00332 Histidine triad family signature 25 43 5.9E-20 T 11-10-2018 IPR001310 Histidine triad (HIT) protein TO73_0474 bf688c5172abd9151dc3ee3c178706f0 105 PRINTS PR00332 Histidine triad family signature 93 103 5.9E-20 T 11-10-2018 IPR001310 Histidine triad (HIT) protein TO73_0474 bf688c5172abd9151dc3ee3c178706f0 105 PRINTS PR00332 Histidine triad family signature 4 20 5.9E-20 T 11-10-2018 IPR001310 Histidine triad (HIT) protein TO73_0474 bf688c5172abd9151dc3ee3c178706f0 105 SUPERFAMILY SSF54197 1 104 2.32E-33 T 11-10-2018 IPR036265 HIT-like superfamily TO73_0461 c51e0c75629c504fad5ae208e29ef5f4 123 Pfam PF09862 Protein of unknown function (DUF2089) 10 119 2.1E-39 T 11-10-2018 IPR018658 Protein of unknown function DUF2089 TO73_0934 151087ac90e9d41bcd8e569806617253 285 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 277 4.8E-42 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_1107 070a692795deef76d84862f0442241de 164 Pfam PF10646 Sporulation and spore germination 101 148 9.7E-6 T 11-10-2018 IPR019606 GerMN domain TO73_0550 4c24620aab16941bdccb09bb4261c263 455 Gene3D G3DSA:3.30.70.3130 1 90 2.2E-34 T 11-10-2018 TO73_0550 4c24620aab16941bdccb09bb4261c263 455 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 325 384 7.1E-18 T 11-10-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain TO73_0550 4c24620aab16941bdccb09bb4261c263 455 Gene3D G3DSA:3.40.50.150 91 393 1.2E-98 T 11-10-2018 TO73_0550 4c24620aab16941bdccb09bb4261c263 455 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 2 91 8.6E-32 T 11-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TO73_0550 4c24620aab16941bdccb09bb4261c263 455 Gene3D G3DSA:2.30.130.60 394 455 6.6E-32 T 11-10-2018 TO73_0550 4c24620aab16941bdccb09bb4261c263 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 172 184 6.7E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TO73_0550 4c24620aab16941bdccb09bb4261c263 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 77 91 6.7E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TO73_0550 4c24620aab16941bdccb09bb4261c263 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 282 299 6.7E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TO73_0550 4c24620aab16941bdccb09bb4261c263 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 106 116 6.7E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TO73_0550 4c24620aab16941bdccb09bb4261c263 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 222 238 6.7E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TO73_0550 4c24620aab16941bdccb09bb4261c263 455 Pfam PF01189 16S rRNA methyltransferase RsmB/F 96 298 1.1E-43 T 11-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TO73_0550 4c24620aab16941bdccb09bb4261c263 455 SUPERFAMILY SSF53335 3 299 1.03E-61 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_2398 126ab70d7eda2268473a0bfacec20afb 358 Gene3D G3DSA:3.90.1580.10 52 218 3.1E-8 T 11-10-2018 TO73_2398 126ab70d7eda2268473a0bfacec20afb 358 Pfam PF03781 Sulfatase-modifying factor enzyme 1 64 180 1.1E-7 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 TO73_2398 126ab70d7eda2268473a0bfacec20afb 358 SUPERFAMILY SSF56436 53 355 2.07E-14 T 11-10-2018 IPR016187 C-type lectin fold TO73_2762 c8452b3045fd156c09e6b86802996c78 174 Pfam PF04098 Rad52/22 family double-strand break repair protein 8 124 1.1E-8 T 11-10-2018 IPR007232 DNA repair protein Rad52/59/22 GO:0006281|GO:0006310 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938 TO73_1480 a9db2798ee0d3c25a84944380b93a237 173 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 4 165 2.0E-36 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TO73_1480 a9db2798ee0d3c25a84944380b93a237 173 SUPERFAMILY SSF46785 2 77 2.36E-10 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1480 a9db2798ee0d3c25a84944380b93a237 173 SUPERFAMILY SSF46785 80 154 1.2E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1480 a9db2798ee0d3c25a84944380b93a237 173 Gene3D G3DSA:1.10.10.10 79 168 2.5E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1480 a9db2798ee0d3c25a84944380b93a237 173 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 163 5.2E-50 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TO73_1480 a9db2798ee0d3c25a84944380b93a237 173 PIRSF PIRSF019345 1 170 4.8E-51 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TO73_1480 a9db2798ee0d3c25a84944380b93a237 173 Gene3D G3DSA:1.10.10.10 1 78 2.1E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0728 d7e55a810f915c3801202993b04ea17d 188 Pfam PF00578 AhpC/TSA family 13 131 7.3E-16 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TO73_0728 d7e55a810f915c3801202993b04ea17d 188 SUPERFAMILY SSF52833 5 183 1.11E-49 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_0728 d7e55a810f915c3801202993b04ea17d 188 Gene3D G3DSA:3.40.30.10 2 188 5.6E-54 T 11-10-2018 TO73_1272 d0e21fe76200cefa54c679721bb4bf89 388 Pfam PF00144 Beta-lactamase 6 355 1.1E-60 T 11-10-2018 IPR001466 Beta-lactamase-related TO73_1272 d0e21fe76200cefa54c679721bb4bf89 388 SUPERFAMILY SSF56601 2 358 6.98E-82 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TO73_1272 d0e21fe76200cefa54c679721bb4bf89 388 Gene3D G3DSA:3.40.710.10 1 387 1.9E-107 T 11-10-2018 TO73_1227 dded79c3885e780bd0a0d9ffff8dc3f5 418 Gene3D G3DSA:3.40.50.720 1 82 2.3E-11 T 11-10-2018 TO73_1227 dded79c3885e780bd0a0d9ffff8dc3f5 418 SUPERFAMILY SSF53244 267 407 1.56E-27 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_1227 dded79c3885e780bd0a0d9ffff8dc3f5 418 Gene3D G3DSA:3.40.1190.10 84 253 1.5E-40 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_1227 dded79c3885e780bd0a0d9ffff8dc3f5 418 SUPERFAMILY SSF53623 86 227 1.18E-37 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_1227 dded79c3885e780bd0a0d9ffff8dc3f5 418 SUPERFAMILY SSF51984 2 81 1.49E-9 T 11-10-2018 TO73_1227 dded79c3885e780bd0a0d9ffff8dc3f5 418 Pfam PF08245 Mur ligase middle domain 99 219 3.0E-24 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TO73_1227 dded79c3885e780bd0a0d9ffff8dc3f5 418 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 1 407 26.373 T 11-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TO73_1227 dded79c3885e780bd0a0d9ffff8dc3f5 418 Gene3D G3DSA:3.90.190.20 267 403 3.0E-27 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_1930 3a762722d37a81fc67cb8a87b42680b5 429 PIRSF PIRSF000505 10 429 8.4E-114 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TO73_1930 3a762722d37a81fc67cb8a87b42680b5 429 SUPERFAMILY SSF55205 9 425 4.19E-121 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TO73_1930 3a762722d37a81fc67cb8a87b42680b5 429 ProSitePatterns PS00885 EPSP synthase signature 2. 342 360 - T 11-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TO73_1930 3a762722d37a81fc67cb8a87b42680b5 429 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 16 425 1.2E-119 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TO73_1930 3a762722d37a81fc67cb8a87b42680b5 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 422 1.6E-115 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TO73_1930 3a762722d37a81fc67cb8a87b42680b5 429 Gene3D G3DSA:3.65.10.10 16 419 6.6E-143 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TO73_1930 3a762722d37a81fc67cb8a87b42680b5 429 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 12 428 33.16 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TO73_1930 3a762722d37a81fc67cb8a87b42680b5 429 Gene3D G3DSA:3.65.10.10 24 232 6.6E-143 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TO73_1609 dc597956a50878dea43964b01540eabe 69 Pfam PF11609 Protein of unknown function (DUF3248) 6 68 2.0E-33 T 11-10-2018 IPR021650 Protein of unknown function DUF3248 TO73_1609 dc597956a50878dea43964b01540eabe 69 Gene3D G3DSA:3.10.20.570 1 69 5.2E-35 T 11-10-2018 TO73_0245 279cacb2bcaeac5d9b96c99073f29212 186 Gene3D G3DSA:1.10.357.10 1 186 3.3E-70 T 11-10-2018 TO73_0245 279cacb2bcaeac5d9b96c99073f29212 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 5.8E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_0245 279cacb2bcaeac5d9b96c99073f29212 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 5.8E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_0245 279cacb2bcaeac5d9b96c99073f29212 186 SUPERFAMILY SSF48498 87 183 1.22E-8 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TO73_0245 279cacb2bcaeac5d9b96c99073f29212 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.8E-14 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_0245 279cacb2bcaeac5d9b96c99073f29212 186 SUPERFAMILY SSF46689 10 77 1.21E-16 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_0618 4274df42df4a2679c1ec12013ab571c6 398 SUPERFAMILY SSF103473 12 391 4.05E-48 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_0618 4274df42df4a2679c1ec12013ab571c6 398 Pfam PF05977 Transmembrane secretion effector 3 384 4.6E-54 T 11-10-2018 IPR010290 Transmembrane secretion effector TO73_0618 4274df42df4a2679c1ec12013ab571c6 398 Gene3D G3DSA:1.20.1250.20 10 387 3.2E-41 T 11-10-2018 TO73_2214 38700c8205388d9b6776040946a5a5af 252 Pfam PF05258 Protein of unknown function (DUF721) 5 90 1.1E-18 T 11-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 TO73_1021 c23aa84b53a487c52c6a7ab5a19646bf 136 Gene3D G3DSA:3.40.50.1010 1 134 6.0E-18 T 11-10-2018 TO73_1021 c23aa84b53a487c52c6a7ab5a19646bf 136 SUPERFAMILY SSF88723 2 128 1.08E-12 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_1021 c23aa84b53a487c52c6a7ab5a19646bf 136 Pfam PF01850 PIN domain 2 86 2.6E-5 T 11-10-2018 IPR002716 PIN domain TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 330 349 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 Gene3D G3DSA:1.20.140.10 228 376 1.8E-58 T 11-10-2018 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 SUPERFAMILY SSF47203 221 374 6.77E-61 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 117 211 1.4E-22 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 113 1.1E-29 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 SUPERFAMILY SSF56645 4 236 4.71E-75 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 Gene3D G3DSA:2.40.110.10 116 227 1.9E-40 T 11-10-2018 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 Gene3D G3DSA:1.10.540.10 3 115 3.4E-32 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 371 4.8E-53 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 PIRSF PIRSF016578 124 374 1.7E-11 T 11-10-2018 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 PIRSF PIRSF016578 3 77 0.017 T 11-10-2018 TO73_0969 f0c3e334e7a47b59a1578468d576fa67 378 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 119 131 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_1583 fa2342d28f91bb7f272dbf1998ad6839 363 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 53 68 - T 11-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1583 fa2342d28f91bb7f272dbf1998ad6839 363 Pfam PF00146 NADH dehydrogenase 14 323 6.9E-117 T 11-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1583 fa2342d28f91bb7f272dbf1998ad6839 363 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216 229 - T 11-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1583 fa2342d28f91bb7f272dbf1998ad6839 363 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 7 329 23.698 T 11-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_0859 b3502a84ec447c9cd324660094069784 85 SUPERFAMILY SSF81593 12 75 7.06E-13 T 11-10-2018 TO73_0859 b3502a84ec447c9cd324660094069784 85 Gene3D G3DSA:1.20.120.330 1 81 1.8E-12 T 11-10-2018 TO73_0859 b3502a84ec447c9cd324660094069784 85 Pfam PF05168 HEPN domain 12 79 1.9E-7 T 11-10-2018 IPR007842 HEPN domain TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 SUPERFAMILY SSF46894 141 211 2.07E-22 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 1.1E-19 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 Gene3D G3DSA:3.40.50.12740 2 211 1.3E-76 T 11-10-2018 TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 SMART SM00421 148 205 6.9E-24 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 SUPERFAMILY SSF52172 2 132 4.41E-38 T 11-10-2018 IPR011006 CheY-like superfamily TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 Pfam PF00072 Response regulator receiver domain 4 116 7.9E-31 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 SMART SM00448 2 115 5.3E-36 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.4E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.4E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_0589 caa08f25fb0cccc8fbcb9c4ba8d6382f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.4E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1308 15bdf722594ac3ba0704f54940ae3f48 742 Gene3D G3DSA:1.10.3810.10 54 250 8.2E-53 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_1308 15bdf722594ac3ba0704f54940ae3f48 742 SUPERFAMILY SSF53955 44 256 2.11E-55 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily TO73_1308 15bdf722594ac3ba0704f54940ae3f48 742 SUPERFAMILY SSF56601 219 658 1.51E-104 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TO73_1308 15bdf722594ac3ba0704f54940ae3f48 742 Pfam PF00905 Penicillin binding protein transpeptidase domain 346 585 4.6E-26 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TO73_1308 15bdf722594ac3ba0704f54940ae3f48 742 Gene3D G3DSA:3.40.710.10 280 668 1.5E-109 T 11-10-2018 TO73_1308 15bdf722594ac3ba0704f54940ae3f48 742 Pfam PF00912 Transglycosylase 68 234 3.0E-51 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_0853 a3a6e41ff4b8073c41af89a22b83dfe9 179 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 73 87 - T 11-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site TO73_0853 a3a6e41ff4b8073c41af89a22b83dfe9 179 Gene3D G3DSA:2.40.37.10 116 153 1.5E-31 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TO73_0853 a3a6e41ff4b8073c41af89a22b83dfe9 179 Gene3D G3DSA:3.20.20.10 1 115 1.5E-31 T 11-10-2018 IPR029066 PLP-binding barrel TO73_0853 a3a6e41ff4b8073c41af89a22b83dfe9 179 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 1 120 2.0E-14 T 11-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TO73_0853 a3a6e41ff4b8073c41af89a22b83dfe9 179 SUPERFAMILY SSF51419 1 123 1.29E-20 T 11-10-2018 IPR029066 PLP-binding barrel TO73_0229 d84d705296bcee384c2618e446dc1196 285 SUPERFAMILY SSF52096 22 277 3.73E-77 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_0229 d84d705296bcee384c2618e446dc1196 285 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 13 270 1.9E-107 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0229 d84d705296bcee384c2618e446dc1196 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 159 177 1.1E-37 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0229 d84d705296bcee384c2618e446dc1196 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 196 213 1.1E-37 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0229 d84d705296bcee384c2618e446dc1196 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 247 256 1.1E-37 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0229 d84d705296bcee384c2618e446dc1196 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 125 139 1.1E-37 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0229 d84d705296bcee384c2618e446dc1196 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 225 236 1.1E-37 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0229 d84d705296bcee384c2618e446dc1196 285 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 4 277 37.903 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TO73_0229 d84d705296bcee384c2618e446dc1196 285 Gene3D G3DSA:3.90.226.10 22 278 1.5E-82 T 11-10-2018 TO73_0229 d84d705296bcee384c2618e446dc1196 285 Pfam PF01039 Carboxyl transferase domain 99 236 2.4E-13 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TO73_2389 eb8ab50ce4d864ad59a9baef37bcfd29 268 Pfam PF02195 ParB-like nuclease domain 26 112 6.7E-28 T 11-10-2018 IPR003115 ParB/Sulfiredoxin TO73_2389 eb8ab50ce4d864ad59a9baef37bcfd29 268 Gene3D G3DSA:1.10.10.2830 100 212 1.1E-46 T 11-10-2018 TO73_2389 eb8ab50ce4d864ad59a9baef37bcfd29 268 Gene3D G3DSA:3.90.1530.30 37 99 6.6E-32 T 11-10-2018 TO73_2389 eb8ab50ce4d864ad59a9baef37bcfd29 268 SUPERFAMILY SSF109709 105 212 4.97E-36 T 11-10-2018 TO73_2389 eb8ab50ce4d864ad59a9baef37bcfd29 268 SMART SM00470 24 113 8.7E-40 T 11-10-2018 IPR003115 ParB/Sulfiredoxin TO73_2389 eb8ab50ce4d864ad59a9baef37bcfd29 268 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 21 187 2.3E-57 T 11-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TO73_2389 eb8ab50ce4d864ad59a9baef37bcfd29 268 SUPERFAMILY SSF110849 24 115 1.67E-31 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TO73_0176 f9f0a29f0ab0c8fdc29aa42c54381f34 208 SMART SM00942 115 184 0.0081 T 11-10-2018 IPR014820 Primase, C-terminal 1 TO73_0384 f026c782d7cc6fb11463eb0d94000d6c 72 Pfam PF00831 Ribosomal L29 protein 11 67 1.6E-19 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0384 f026c782d7cc6fb11463eb0d94000d6c 72 ProSitePatterns PS00579 Ribosomal protein L29 signature. 46 60 - T 11-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0384 f026c782d7cc6fb11463eb0d94000d6c 72 Gene3D G3DSA:1.20.58.1890 1 72 1.3E-28 T 11-10-2018 TO73_0384 f026c782d7cc6fb11463eb0d94000d6c 72 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 7 67 15.777 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0384 f026c782d7cc6fb11463eb0d94000d6c 72 SUPERFAMILY SSF46561 9 70 7.72E-18 T 11-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0384 f026c782d7cc6fb11463eb0d94000d6c 72 TIGRFAM TIGR00012 L29: ribosomal protein uL29 14 67 6.5E-21 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 Gene3D G3DSA:2.40.110.10 123 241 8.6E-35 T 11-10-2018 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 2.7E-29 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 222 1.6E-20 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 384 3.3E-51 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 PIRSF PIRSF016578 6 383 4.4E-30 T 11-10-2018 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 SUPERFAMILY SSF56645 5 248 7.98E-71 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 Gene3D G3DSA:1.10.540.10 2 122 9.3E-35 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 SUPERFAMILY SSF47203 233 385 1.77E-59 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TO73_2352 c3c607aaab3ae3765ed9c92d7c55974d 387 Gene3D G3DSA:1.20.140.10 242 386 1.5E-56 T 11-10-2018 TO73_2091 f9c25ec341b527034f8fc9db1bfe36c3 376 Gene3D G3DSA:3.40.350.10 3 110 1.4E-5 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TO73_2091 f9c25ec341b527034f8fc9db1bfe36c3 376 Gene3D G3DSA:3.90.230.10 142 373 1.8E-42 T 11-10-2018 TO73_2091 f9c25ec341b527034f8fc9db1bfe36c3 376 SUPERFAMILY SSF55920 140 370 8.9E-41 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like TO73_2091 f9c25ec341b527034f8fc9db1bfe36c3 376 Pfam PF00557 Metallopeptidase family M24 149 359 3.1E-35 T 11-10-2018 IPR000994 Peptidase M24 TO73_2029 ab31ee4af9461762ad5880549034bb9e 462 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 13 455 1.6E-164 T 11-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TO73_2029 ab31ee4af9461762ad5880549034bb9e 462 PRINTS PR00095 Anthranilate synthase component I signature 309 322 3.7E-23 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TO73_2029 ab31ee4af9461762ad5880549034bb9e 462 PRINTS PR00095 Anthranilate synthase component I signature 295 308 3.7E-23 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TO73_2029 ab31ee4af9461762ad5880549034bb9e 462 PRINTS PR00095 Anthranilate synthase component I signature 404 418 3.7E-23 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TO73_2029 ab31ee4af9461762ad5880549034bb9e 462 PRINTS PR00095 Anthranilate synthase component I signature 389 403 3.7E-23 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TO73_2029 ab31ee4af9461762ad5880549034bb9e 462 Gene3D G3DSA:3.60.120.10 1 461 8.0E-178 T 11-10-2018 IPR005801 ADC synthase GO:0009058 TO73_2029 ab31ee4af9461762ad5880549034bb9e 462 Pfam PF00425 chorismate binding enzyme 194 447 9.5E-99 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TO73_2029 ab31ee4af9461762ad5880549034bb9e 462 Pfam PF04715 Anthranilate synthase component I, N terminal region 14 149 9.4E-33 T 11-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TO73_2029 ab31ee4af9461762ad5880549034bb9e 462 SUPERFAMILY SSF56322 6 457 4.06E-154 T 11-10-2018 IPR005801 ADC synthase GO:0009058 TO73_1694 d5cafb4c42d7d242ef536faa5ff8fde3 227 Pfam PF00149 Calcineurin-like phosphoesterase 1 193 1.1E-9 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TO73_1694 d5cafb4c42d7d242ef536faa5ff8fde3 227 SUPERFAMILY SSF56300 1 213 7.44E-27 T 11-10-2018 TO73_1694 d5cafb4c42d7d242ef536faa5ff8fde3 227 PIRSF PIRSF033094 1 227 9.5E-88 T 11-10-2018 IPR014578 Predicted phosphoesterase, CT488 type TO73_0516 c7342373b5f7b2bf2bb2ac6ec333d438 189 SUPERFAMILY SSF46626 10 178 9.46E-18 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0516 c7342373b5f7b2bf2bb2ac6ec333d438 189 PIRSF PIRSF024608 1 186 4.2E-71 T 11-10-2018 IPR016823 Sulfur oxidation c-type cytochrome SoxX, type II TO73_0516 c7342373b5f7b2bf2bb2ac6ec333d438 189 Gene3D G3DSA:1.10.760.10 24 186 2.1E-50 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0516 c7342373b5f7b2bf2bb2ac6ec333d438 189 Pfam PF00034 Cytochrome c 90 178 5.3E-6 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0516 c7342373b5f7b2bf2bb2ac6ec333d438 189 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 99 179 5.4E-23 T 11-10-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX TO73_2329 bf148410ac4ae8b8892e062ea98e1a8a 129 Gene3D G3DSA:3.30.460.10 1 95 2.7E-14 T 11-10-2018 TO73_2329 bf148410ac4ae8b8892e062ea98e1a8a 129 SUPERFAMILY SSF81301 7 90 2.97E-12 T 11-10-2018 TO73_2329 bf148410ac4ae8b8892e062ea98e1a8a 129 Pfam PF01909 Nucleotidyltransferase domain 12 66 1.4E-7 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TO73_0479 84e9c4c004e0341bf80feef0588fa900 201 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 66 189 2.4E-15 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0479 84e9c4c004e0341bf80feef0588fa900 201 SUPERFAMILY SSF56784 2 194 7.04E-34 T 11-10-2018 IPR036412 HAD-like superfamily TO73_0479 84e9c4c004e0341bf80feef0588fa900 201 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 52 187 1.0E-7 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0479 84e9c4c004e0341bf80feef0588fa900 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 1.3E-11 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0479 84e9c4c004e0341bf80feef0588fa900 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 1.3E-11 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0479 84e9c4c004e0341bf80feef0588fa900 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 107 120 1.3E-11 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0479 84e9c4c004e0341bf80feef0588fa900 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.3E-11 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TO73_0479 84e9c4c004e0341bf80feef0588fa900 201 Gene3D G3DSA:3.40.50.1000 1 199 8.9E-35 T 11-10-2018 IPR023214 HAD superfamily TO73_0479 84e9c4c004e0341bf80feef0588fa900 201 Pfam PF13419 Haloacid dehalogenase-like hydrolase 87 190 2.1E-16 T 11-10-2018 TO73_2051 5a0eeddc5015145071bb8a912d8aa4ea 540 SUPERFAMILY SSF51905 1 537 2.07E-38 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_2051 5a0eeddc5015145071bb8a912d8aa4ea 540 PIRSF PIRSF036654 1 539 2.3E-255 T 11-10-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 TO73_2051 5a0eeddc5015145071bb8a912d8aa4ea 540 Gene3D G3DSA:3.50.50.60 460 538 1.4E-11 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_2051 5a0eeddc5015145071bb8a912d8aa4ea 540 Pfam PF00890 FAD binding domain 1 521 5.5E-98 T 11-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_2051 5a0eeddc5015145071bb8a912d8aa4ea 540 Gene3D G3DSA:3.50.50.60 1 285 1.9E-43 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0940 f143969f5ae9f505c21c17fdc1714694 233 Gene3D G3DSA:1.40.20.10 2 226 4.9E-25 T 11-10-2018 IPR038186 CHAD domain superfamily TO73_0940 f143969f5ae9f505c21c17fdc1714694 233 SMART SM00880 3 224 4.3E-15 T 11-10-2018 IPR007899 CHAD domain TO73_0940 f143969f5ae9f505c21c17fdc1714694 233 Pfam PF05235 CHAD domain 8 191 3.2E-25 T 11-10-2018 IPR007899 CHAD domain TO73_1902 2ca8a3af2273b2118cd958447d1b53da 576 SUPERFAMILY SSF52540 379 569 4.26E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1902 2ca8a3af2273b2118cd958447d1b53da 576 Pfam PF00005 ABC transporter 391 516 2.6E-15 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1902 2ca8a3af2273b2118cd958447d1b53da 576 Gene3D G3DSA:3.40.50.300 368 573 6.8E-35 T 11-10-2018 TO73_1902 2ca8a3af2273b2118cd958447d1b53da 576 Pfam PF00583 Acetyltransferase (GNAT) family 220 292 1.5E-7 T 11-10-2018 IPR000182 GNAT domain TO73_1902 2ca8a3af2273b2118cd958447d1b53da 576 SUPERFAMILY SSF55729 97 298 4.18E-13 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_1902 2ca8a3af2273b2118cd958447d1b53da 576 SMART SM00382 399 576 3.4E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1477 34ca9dc4a5161c08ccbc368fd5c43591 162 Pfam PF01878 EVE domain 14 155 2.7E-46 T 11-10-2018 IPR002740 EVE domain TO73_1477 34ca9dc4a5161c08ccbc368fd5c43591 162 Gene3D G3DSA:3.10.590.10 4 161 9.3E-51 T 11-10-2018 TO73_1477 34ca9dc4a5161c08ccbc368fd5c43591 162 SUPERFAMILY SSF88697 11 160 9.94E-55 T 11-10-2018 IPR015947 PUA-like superfamily TO73_0994 821ca867880b460c2de42a57a36531fc 445 Pfam PF00501 AMP-binding enzyme 79 285 2.5E-14 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_0994 821ca867880b460c2de42a57a36531fc 445 Gene3D G3DSA:3.40.50.12780 2 326 4.2E-127 T 11-10-2018 TO73_0994 821ca867880b460c2de42a57a36531fc 445 Gene3D G3DSA:3.30.300.30 327 445 1.0E-31 T 11-10-2018 TO73_0994 821ca867880b460c2de42a57a36531fc 445 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 444 2.9E-30 T 11-10-2018 IPR028154 AMP-dependent ligase, C-terminal TO73_0994 821ca867880b460c2de42a57a36531fc 445 SUPERFAMILY SSF56801 24 439 4.19E-61 T 11-10-2018 TO73_0994 821ca867880b460c2de42a57a36531fc 445 PIRSF PIRSF006444 1 445 1.7E-187 T 11-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 TO73_1907 a4e914de316b36d33f65091f5cac1fe4 325 Pfam PF01368 DHH family 28 162 7.2E-10 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TO73_1907 a4e914de316b36d33f65091f5cac1fe4 325 Pfam PF02272 DHHA1 domain 251 315 6.3E-10 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TO73_1907 a4e914de316b36d33f65091f5cac1fe4 325 SUPERFAMILY SSF64182 27 320 2.88E-52 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily TO73_1907 a4e914de316b36d33f65091f5cac1fe4 325 Gene3D G3DSA:3.90.1640.10 12 200 1.4E-47 T 11-10-2018 TO73_1907 a4e914de316b36d33f65091f5cac1fe4 325 Gene3D G3DSA:3.10.310.30 204 321 1.6E-19 T 11-10-2018 TO73_0487 9b9c6cefe544b657bda47a7db4ca9ec6 88 Pfam PF11950 Protein of unknown function (DUF3467) 6 79 9.3E-18 T 11-10-2018 IPR021857 Protein of unknown function DUF3467 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 PRINTS PR00690 Adhesin family signature 48 61 8.7E-13 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 PRINTS PR00690 Adhesin family signature 177 198 8.7E-13 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 PRINTS PR00690 Adhesin family signature 17 35 8.7E-13 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 PRINTS PR00690 Adhesin family signature 61 78 8.7E-13 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 PRINTS PR00691 Adhesin B signature 42 60 1.6E-16 T 11-10-2018 IPR006129 Adhesin B GO:0007155 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 PRINTS PR00691 Adhesin B signature 61 80 1.6E-16 T 11-10-2018 IPR006129 Adhesin B GO:0007155 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 PRINTS PR00691 Adhesin B signature 17 38 1.6E-16 T 11-10-2018 IPR006129 Adhesin B GO:0007155 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 PRINTS PR00691 Adhesin B signature 123 142 1.6E-16 T 11-10-2018 IPR006129 Adhesin B GO:0007155 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 Gene3D G3DSA:3.40.50.1980 182 283 4.7E-22 T 11-10-2018 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 SUPERFAMILY SSF53807 9 282 3.97E-71 T 11-10-2018 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 Gene3D G3DSA:3.40.50.1980 16 180 3.8E-43 T 11-10-2018 TO73_1035 38e81a6bd78df0e8672f18c040a6320c 284 Pfam PF01297 Zinc-uptake complex component A periplasmic 20 282 2.4E-65 T 11-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TO73_1848 18993825724abde83b931b3910d2e8cd 408 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 19 329 1.3E-71 T 11-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 TO73_1848 18993825724abde83b931b3910d2e8cd 408 SUPERFAMILY SSF46548 147 242 1.88E-15 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TO73_1848 18993825724abde83b931b3910d2e8cd 408 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 179 190 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_1848 18993825724abde83b931b3910d2e8cd 408 Pfam PF13484 4Fe-4S double cluster binding domain 178 242 1.4E-16 T 11-10-2018 TO73_1848 18993825724abde83b931b3910d2e8cd 408 Pfam PF13646 HEAT repeats 305 356 1.7E-6 T 11-10-2018 TO73_1848 18993825724abde83b931b3910d2e8cd 408 Pfam PF08331 Domain of unknown function (DUF1730) 52 125 2.9E-11 T 11-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 TO73_1848 18993825724abde83b931b3910d2e8cd 408 SUPERFAMILY SSF48371 290 381 3.32E-9 T 11-10-2018 IPR016024 Armadillo-type fold TO73_1848 18993825724abde83b931b3910d2e8cd 408 Gene3D G3DSA:1.25.10.10 284 387 1.0E-7 T 11-10-2018 IPR011989 Armadillo-like helical TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 604 2.8E-194 T 11-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 345 367 3.1E-7 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 405 427 3.1E-7 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 72 92 3.1E-7 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 70 95 1.7E-58 T 11-10-2018 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 98 118 1.7E-58 T 11-10-2018 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 406 425 1.7E-58 T 11-10-2018 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 302 314 1.7E-58 T 11-10-2018 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 145 166 1.7E-58 T 11-10-2018 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 234 260 1.7E-58 T 11-10-2018 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 212 233 1.7E-58 T 11-10-2018 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 Pfam PF00361 Proton-conducting membrane transporter 125 394 9.2E-83 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1587 3769b24064da46d5774aeaedffd5a0bc 606 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 63 109 2.3E-19 T 11-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1437 62cdc738940a7d4ff3e45c41676f28d9 286 SUPERFAMILY SSF161098 16 277 3.01E-49 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1437 62cdc738940a7d4ff3e45c41676f28d9 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 276 4.5E-12 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1437 62cdc738940a7d4ff3e45c41676f28d9 286 Gene3D G3DSA:1.10.3720.10 12 284 3.3E-50 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0872 90d2fecbe47883a17a9106736d06ca77 350 Pfam PF01747 ATP-sulfurylase 140 347 9.7E-80 T 11-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TO73_0872 90d2fecbe47883a17a9106736d06ca77 350 Gene3D G3DSA:3.40.50.620 137 349 2.2E-92 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_0872 90d2fecbe47883a17a9106736d06ca77 350 Pfam PF14306 PUA-like domain 4 132 2.7E-35 T 11-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TO73_0872 90d2fecbe47883a17a9106736d06ca77 350 SUPERFAMILY SSF52374 140 347 1.16E-72 T 11-10-2018 TO73_0872 90d2fecbe47883a17a9106736d06ca77 350 Gene3D G3DSA:3.10.400.10 2 136 9.0E-43 T 11-10-2018 TO73_0872 90d2fecbe47883a17a9106736d06ca77 350 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 4 347 3.5E-97 T 11-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TO73_0872 90d2fecbe47883a17a9106736d06ca77 350 SUPERFAMILY SSF88697 4 133 4.77E-35 T 11-10-2018 IPR015947 PUA-like superfamily TO73_0116 76a4cf9b31dd8f2b674e8130b496f9fd 343 SUPERFAMILY SSF101821 70 177 1.43E-24 T 11-10-2018 TO73_0116 76a4cf9b31dd8f2b674e8130b496f9fd 343 Gene3D G3DSA:3.40.630.10 10 338 1.4E-105 T 11-10-2018 TO73_0116 76a4cf9b31dd8f2b674e8130b496f9fd 343 SUPERFAMILY SSF53187 8 341 2.17E-55 T 11-10-2018 TO73_0116 76a4cf9b31dd8f2b674e8130b496f9fd 343 PIRSF PIRSF001123 4 343 1.1E-90 T 11-10-2018 IPR008007 Peptidase M42 TO73_0116 76a4cf9b31dd8f2b674e8130b496f9fd 343 Gene3D G3DSA:2.40.30.40 70 161 1.4E-105 T 11-10-2018 IPR023367 Peptidase M42, domain 2 TO73_0116 76a4cf9b31dd8f2b674e8130b496f9fd 343 Pfam PF05343 M42 glutamyl aminopeptidase 46 335 3.3E-83 T 11-10-2018 IPR008007 Peptidase M42 TO73_0150 d486884dac55c4059419f0ed699f3db3 246 Gene3D G3DSA:3.30.70.1030 1 119 3.4E-40 T 11-10-2018 TO73_0150 d486884dac55c4059419f0ed699f3db3 246 Pfam PF06778 Chlorite dismutase 34 233 1.1E-62 T 11-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase TO73_0150 d486884dac55c4059419f0ed699f3db3 246 SUPERFAMILY SSF54909 3 244 2.49E-80 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel TO73_0150 d486884dac55c4059419f0ed699f3db3 246 Gene3D G3DSA:3.30.70.1100 120 245 3.8E-53 T 11-10-2018 TO73_2264 234047455c59649dab4d847abc18be96 451 Pfam PF01235 Sodium:alanine symporter family 65 440 1.7E-93 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TO73_2264 234047455c59649dab4d847abc18be96 451 PRINTS PR00175 Sodium/alanine symporter signature 96 118 3.8E-32 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TO73_2264 234047455c59649dab4d847abc18be96 451 PRINTS PR00175 Sodium/alanine symporter signature 187 205 3.8E-32 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TO73_2264 234047455c59649dab4d847abc18be96 451 PRINTS PR00175 Sodium/alanine symporter signature 410 430 3.8E-32 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TO73_2264 234047455c59649dab4d847abc18be96 451 PRINTS PR00175 Sodium/alanine symporter signature 215 234 3.8E-32 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TO73_2264 234047455c59649dab4d847abc18be96 451 PRINTS PR00175 Sodium/alanine symporter signature 309 327 3.8E-32 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TO73_2264 234047455c59649dab4d847abc18be96 451 PRINTS PR00175 Sodium/alanine symporter signature 351 373 3.8E-32 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TO73_2264 234047455c59649dab4d847abc18be96 451 TIGRFAM TIGR00835 agcS: amino acid carrier protein 21 434 4.5E-96 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TO73_0381 98ec6e239f1d8fd29cb11930d79e72b0 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 106 4.2E-39 T 11-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0381 98ec6e239f1d8fd29cb11930d79e72b0 113 Gene3D G3DSA:3.90.470.10 1 113 1.7E-46 T 11-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0381 98ec6e239f1d8fd29cb11930d79e72b0 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 11-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0381 98ec6e239f1d8fd29cb11930d79e72b0 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 28.909 T 11-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0381 98ec6e239f1d8fd29cb11930d79e72b0 113 SUPERFAMILY SSF54843 1 110 3.14E-41 T 11-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TO73_0381 98ec6e239f1d8fd29cb11930d79e72b0 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 1.1E-33 T 11-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TO73_0471 7fa9f969011684b391f562f1b71d7b43 204 Gene3D G3DSA:3.20.20.70 6 203 6.8E-78 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_0471 7fa9f969011684b391f562f1b71d7b43 204 SUPERFAMILY SSF51366 7 200 8.0E-55 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TO73_0471 7fa9f969011684b391f562f1b71d7b43 204 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 6 204 34.164 T 11-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 TO73_0471 7fa9f969011684b391f562f1b71d7b43 204 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 8 198 6.2E-39 T 11-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 TO73_0337 e14ff52368f56a976bd9b6e33e100bc7 377 SUPERFAMILY SSF103473 26 358 7.46E-9 T 11-10-2018 IPR036259 MFS transporter superfamily TO73_0337 e14ff52368f56a976bd9b6e33e100bc7 377 Gene3D G3DSA:1.20.1250.20 104 358 9.0E-6 T 11-10-2018 TO73_0070 1babe19fba3eec96cff82036b4b5e872 304 SUPERFAMILY SSF51730 1 290 3.92E-103 T 11-10-2018 IPR029041 FAD-linked oxidoreductase-like TO73_0070 1babe19fba3eec96cff82036b4b5e872 304 Gene3D G3DSA:3.20.20.220 1 291 7.1E-121 T 11-10-2018 TO73_0070 1babe19fba3eec96cff82036b4b5e872 304 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 14 286 7.3E-101 T 11-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 TO73_0070 1babe19fba3eec96cff82036b4b5e872 304 Pfam PF02219 Methylenetetrahydrofolate reductase 2 287 7.7E-97 T 11-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TO73_1298 2efc226b425739be6c81d9e693cd3b34 490 Pfam PF02386 Cation transport protein 78 482 2.4E-59 T 11-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 TO73_1298 2efc226b425739be6c81d9e693cd3b34 490 PIRSF PIRSF006247 9 488 2.4E-163 T 11-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 TO73_0929 a0d8250d271f6a892c49292ac2ed7747 494 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 11-10-2018 IPR020845 AMP-binding, conserved site TO73_0929 a0d8250d271f6a892c49292ac2ed7747 494 Gene3D G3DSA:3.40.50.12780 5 386 3.4E-104 T 11-10-2018 TO73_0929 a0d8250d271f6a892c49292ac2ed7747 494 Gene3D G3DSA:3.30.300.310 389 494 8.9E-36 T 11-10-2018 TO73_0929 a0d8250d271f6a892c49292ac2ed7747 494 Pfam PF13193 AMP-binding enzyme C-terminal domain 402 477 2.9E-24 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TO73_0929 a0d8250d271f6a892c49292ac2ed7747 494 SUPERFAMILY SSF56801 5 489 4.84E-150 T 11-10-2018 TO73_0929 a0d8250d271f6a892c49292ac2ed7747 494 Pfam PF00501 AMP-binding enzyme 9 393 1.0E-89 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_0797 51cae9d3afb6c1c49098325bee9b1763 54 Pfam PF02416 mttA/Hcf106 family 3 53 7.0E-19 T 11-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TO73_0797 51cae9d3afb6c1c49098325bee9b1763 54 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 3.8E-20 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TO73_0797 51cae9d3afb6c1c49098325bee9b1763 54 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 53 17.768 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TO73_2191 ffcc5b1bf3cc6ef75a22f836f34c3566 377 Pfam PF00155 Aminotransferase class I and II 27 369 9.6E-35 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TO73_2191 ffcc5b1bf3cc6ef75a22f836f34c3566 377 SUPERFAMILY SSF53383 18 375 3.81E-87 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_2191 ffcc5b1bf3cc6ef75a22f836f34c3566 377 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 227 240 - T 11-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TO73_2191 ffcc5b1bf3cc6ef75a22f836f34c3566 377 Gene3D G3DSA:3.90.1150.10 27 369 2.2E-122 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_2191 ffcc5b1bf3cc6ef75a22f836f34c3566 377 Gene3D G3DSA:3.40.640.10 58 276 2.2E-122 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_2143 249d4dd7d9793648775b07d6faee24bf 265 Pfam PF02535 ZIP Zinc transporter 114 260 1.2E-15 T 11-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 TO73_2322 27cca17bb69cc1f2b43d1c6822ce6770 323 Pfam PF03969 AFG1-like ATPase 14 203 2.4E-26 T 11-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 TO73_2322 27cca17bb69cc1f2b43d1c6822ce6770 323 Pfam PF03969 AFG1-like ATPase 226 321 3.7E-10 T 11-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 TO73_2322 27cca17bb69cc1f2b43d1c6822ce6770 323 SUPERFAMILY SSF52540 64 188 2.05E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2322 27cca17bb69cc1f2b43d1c6822ce6770 323 Gene3D G3DSA:3.40.50.300 9 190 3.9E-14 T 11-10-2018 TO73_0882 fcd73fe74de05e82f40870b68a6cee8f 324 Pfam PF01032 FecCD transport family 17 319 8.4E-73 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TO73_0882 fcd73fe74de05e82f40870b68a6cee8f 324 SUPERFAMILY SSF81345 4 319 1.83E-66 T 11-10-2018 IPR037294 ABC transporter, BtuC-like TO73_0882 fcd73fe74de05e82f40870b68a6cee8f 324 Gene3D G3DSA:1.10.3470.10 3 323 8.8E-84 T 11-10-2018 IPR037294 ABC transporter, BtuC-like TO73_2824 fcd5cd0aba77e07a2fc4ddc3710f6049 402 Gene3D G3DSA:3.40.30.10 223 397 2.0E-27 T 11-10-2018 TO73_2824 fcd5cd0aba77e07a2fc4ddc3710f6049 402 Pfam PF00578 AhpC/TSA family 228 374 6.3E-18 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TO73_2824 fcd5cd0aba77e07a2fc4ddc3710f6049 402 SUPERFAMILY SSF52833 223 397 2.02E-25 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_0852 3a2381b87a8e41a06e31a7b6029047d4 133 Gene3D G3DSA:2.40.37.10 14 26 2.3E-24 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TO73_0852 3a2381b87a8e41a06e31a7b6029047d4 133 Gene3D G3DSA:3.20.20.10 27 131 2.3E-24 T 11-10-2018 IPR029066 PLP-binding barrel TO73_0852 3a2381b87a8e41a06e31a7b6029047d4 133 SUPERFAMILY SSF51419 18 131 5.4E-21 T 11-10-2018 IPR029066 PLP-binding barrel TO73_0852 3a2381b87a8e41a06e31a7b6029047d4 133 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 28 131 1.2E-13 T 11-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TO73_1734 f8336cef702bcf08de8494a67da08ea9 161 Pfam PF04008 Adenosine specific kinase 6 160 5.2E-71 T 11-10-2018 IPR007153 Adenosine specific kinase TO73_1734 f8336cef702bcf08de8494a67da08ea9 161 Gene3D G3DSA:3.40.1520.10 1 161 4.7E-75 T 11-10-2018 IPR036902 Ta1353-like superfamily TO73_1734 f8336cef702bcf08de8494a67da08ea9 161 SUPERFAMILY SSF103165 1 161 3.92E-70 T 11-10-2018 IPR036902 Ta1353-like superfamily TO73_1069 8bbd9a46e924a4e4ea35edbb5c70d49c 235 Pfam PF00535 Glycosyl transferase family 2 6 157 4.9E-30 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TO73_1069 8bbd9a46e924a4e4ea35edbb5c70d49c 235 SUPERFAMILY SSF53448 1 210 2.01E-54 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1069 8bbd9a46e924a4e4ea35edbb5c70d49c 235 Gene3D G3DSA:3.90.550.10 1 201 1.5E-47 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0102 b7391282d67a764643cfad635992b5c1 291 SUPERFAMILY SSF56317 4 267 1.03E-54 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TO73_0102 b7391282d67a764643cfad635992b5c1 291 Pfam PF00795 Carbon-nitrogen hydrolase 5 260 8.5E-31 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TO73_0102 b7391282d67a764643cfad635992b5c1 291 Gene3D G3DSA:3.60.110.10 2 264 1.4E-61 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TO73_0347 fcd0d3dce4694e9c2760988b4a485a79 316 Pfam PF00248 Aldo/keto reductase family 15 312 6.5E-70 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain TO73_0347 fcd0d3dce4694e9c2760988b4a485a79 316 SUPERFAMILY SSF51430 1 313 4.06E-96 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TO73_0347 fcd0d3dce4694e9c2760988b4a485a79 316 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 110 120 1.3E-9 T 11-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TO73_0347 fcd0d3dce4694e9c2760988b4a485a79 316 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 268 281 1.3E-9 T 11-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TO73_0347 fcd0d3dce4694e9c2760988b4a485a79 316 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 255 267 1.3E-9 T 11-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TO73_0347 fcd0d3dce4694e9c2760988b4a485a79 316 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 161 180 1.3E-9 T 11-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TO73_0347 fcd0d3dce4694e9c2760988b4a485a79 316 Gene3D G3DSA:3.20.20.100 1 316 3.2E-111 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TO73_2154 ff94a4477d8d810d817b4d83a7ec1b21 197 Gene3D G3DSA:1.10.287.1080 1 123 1.3E-43 T 11-10-2018 TO73_2154 ff94a4477d8d810d817b4d83a7ec1b21 197 TIGRFAM TIGR00444 mazG: MazG family protein 10 149 1.1E-45 T 11-10-2018 IPR011551 NTP pyrophosphohydrolase MazG TO73_2154 ff94a4477d8d810d817b4d83a7ec1b21 197 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 26 99 5.6E-27 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TO73_2154 ff94a4477d8d810d817b4d83a7ec1b21 197 SUPERFAMILY SSF101386 3 103 1.21E-23 T 11-10-2018 TO73_2844 325215c629e4b762c93173da044ba3eb 495 Gene3D G3DSA:2.60.40.10 237 332 4.3E-8 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_2844 325215c629e4b762c93173da044ba3eb 495 SUPERFAMILY SSF49299 263 329 1.96E-7 T 11-10-2018 IPR035986 PKD domain superfamily TO73_2164 2945bc4577befd2315eca45d97f4d7cb 157 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 1 156 34.99 T 11-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_2164 2945bc4577befd2315eca45d97f4d7cb 157 Pfam PF01967 MoaC family 13 148 1.9E-53 T 11-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_2164 2945bc4577befd2315eca45d97f4d7cb 157 Gene3D G3DSA:3.30.70.640 1 157 5.1E-70 T 11-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_2164 2945bc4577befd2315eca45d97f4d7cb 157 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 7 150 4.0E-58 T 11-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_2164 2945bc4577befd2315eca45d97f4d7cb 157 SUPERFAMILY SSF55040 9 153 2.62E-57 T 11-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TO73_1097 c02cab1aca8145155f876dbd58ca1587 372 Gene3D G3DSA:3.90.1150.10 24 362 2.5E-136 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1097 c02cab1aca8145155f876dbd58ca1587 372 Gene3D G3DSA:3.40.640.10 40 270 2.5E-136 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1097 c02cab1aca8145155f876dbd58ca1587 372 SUPERFAMILY SSF53383 5 365 2.76E-100 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1097 c02cab1aca8145155f876dbd58ca1587 372 Pfam PF00155 Aminotransferase class I and II 28 362 3.6E-56 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TO73_0525 7b35aea7fcc2bb446e9a931393868ea2 221 PIRSF PIRSF002764 1 218 3.4E-35 T 11-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria TO73_0525 7b35aea7fcc2bb446e9a931393868ea2 221 Pfam PF03379 CcmB protein 6 214 1.7E-33 T 11-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0525 7b35aea7fcc2bb446e9a931393868ea2 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 28 49 3.0E-11 T 11-10-2018 TO73_0525 7b35aea7fcc2bb446e9a931393868ea2 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 77 100 3.0E-11 T 11-10-2018 TO73_0525 7b35aea7fcc2bb446e9a931393868ea2 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 157 176 3.0E-11 T 11-10-2018 TO73_0525 7b35aea7fcc2bb446e9a931393868ea2 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 54 71 3.0E-11 T 11-10-2018 TO73_1991 6f52d0dd5052bd6f25ca432b1cbcc683 203 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 181 7.6E-51 T 11-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TO73_1991 6f52d0dd5052bd6f25ca432b1cbcc683 203 SUPERFAMILY SSF53850 4 202 4.13E-57 T 11-10-2018 TO73_1991 6f52d0dd5052bd6f25ca432b1cbcc683 203 Pfam PF01634 ATP phosphoribosyltransferase 53 201 1.3E-41 T 11-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TO73_1991 6f52d0dd5052bd6f25ca432b1cbcc683 203 Gene3D G3DSA:3.40.190.10 94 176 3.5E-67 T 11-10-2018 TO73_1991 6f52d0dd5052bd6f25ca432b1cbcc683 203 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 5 203 44.76 T 11-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 TO73_1991 6f52d0dd5052bd6f25ca432b1cbcc683 203 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 140 161 - T 11-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 TO73_1991 6f52d0dd5052bd6f25ca432b1cbcc683 203 Gene3D G3DSA:3.40.190.10 7 198 3.5E-67 T 11-10-2018 TO73_0232 ef69b407c7656a914c240f7b622ef0e1 205 Pfam PF13630 SdpI/YhfL protein family 128 183 1.2E-11 T 11-10-2018 IPR025962 SdpI/YhfL protein family TO73_0232 ef69b407c7656a914c240f7b622ef0e1 205 Pfam PF07853 Protein of unknown function (DUF1648) 3 47 2.3E-17 T 11-10-2018 IPR012867 Domain of unknown function DUF1648 TO73_0232 ef69b407c7656a914c240f7b622ef0e1 205 PIRSF PIRSF038959 2 203 6.4E-26 T 11-10-2018 IPR026272 Immunity protein SdpI TO73_1466 45d8597bc6f27fefc206f3b6c52261a6 270 Gene3D G3DSA:3.40.190.10 6 255 6.4E-69 T 11-10-2018 TO73_1466 45d8597bc6f27fefc206f3b6c52261a6 270 Hamap MF_00995 Chorismate dehydratase [mqnA]. 4 265 27.402 T 11-10-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TO73_1466 45d8597bc6f27fefc206f3b6c52261a6 270 Pfam PF02621 Menaquinone biosynthesis 3 258 1.3E-60 T 11-10-2018 IPR003773 Menaquinone biosynthesis enzyme TO73_1466 45d8597bc6f27fefc206f3b6c52261a6 270 SUPERFAMILY SSF53850 4 258 1.16E-68 T 11-10-2018 TO73_1466 45d8597bc6f27fefc206f3b6c52261a6 270 Gene3D G3DSA:3.40.190.10 72 194 6.4E-69 T 11-10-2018 TO73_0832 f590b3215edf843534732f5242260cbc 242 Gene3D G3DSA:3.40.50.720 1 242 8.1E-72 T 11-10-2018 TO73_0832 f590b3215edf843534732f5242260cbc 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TO73_0832 f590b3215edf843534732f5242260cbc 242 Pfam PF00106 short chain dehydrogenase 5 190 1.3E-36 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0832 f590b3215edf843534732f5242260cbc 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 169 0.0081 T 11-10-2018 TO73_0832 f590b3215edf843534732f5242260cbc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0832 f590b3215edf843534732f5242260cbc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0832 f590b3215edf843534732f5242260cbc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0832 f590b3215edf843534732f5242260cbc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0832 f590b3215edf843534732f5242260cbc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0832 f590b3215edf843534732f5242260cbc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 76 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0832 f590b3215edf843534732f5242260cbc 242 SUPERFAMILY SSF51735 3 238 7.61E-63 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0832 f590b3215edf843534732f5242260cbc 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 5.8E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0832 f590b3215edf843534732f5242260cbc 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 65 76 5.8E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_0832 f590b3215edf843534732f5242260cbc 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 5.8E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 5.5E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 198 211 5.5E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 182 194 5.5E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 5.5E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 Gene3D G3DSA:3.30.930.10 102 438 1.9E-102 T 11-10-2018 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 SUPERFAMILY SSF50249 9 96 3.64E-23 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 438 42.04 T 11-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 SUPERFAMILY SSF55681 111 432 5.18E-87 T 11-10-2018 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 4 436 7.0E-145 T 11-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 Pfam PF01336 OB-fold nucleic acid binding domain 16 94 4.7E-15 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 113 432 9.1E-76 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TO73_1634 cacf5c09c130bd5a2f5388e399b939b1 438 Gene3D G3DSA:2.40.50.140 2 97 2.4E-23 T 11-10-2018 TO73_1681 4a7206e57565e5dd38fbdcf6fd9e9195 193 ProSitePatterns PS01127 Elongation factor Ts signature 2. 72 82 - T 11-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_1681 4a7206e57565e5dd38fbdcf6fd9e9195 193 SUPERFAMILY SSF54713 52 192 2.88E-54 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TO73_1681 4a7206e57565e5dd38fbdcf6fd9e9195 193 Pfam PF00889 Elongation factor TS 31 192 2.1E-39 T 11-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 TO73_1681 4a7206e57565e5dd38fbdcf6fd9e9195 193 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 2 92 7.5E-32 T 11-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_1681 4a7206e57565e5dd38fbdcf6fd9e9195 193 Gene3D G3DSA:1.10.286.20 108 151 4.7E-21 T 11-10-2018 TO73_1681 4a7206e57565e5dd38fbdcf6fd9e9195 193 Hamap MF_00050 Elongation factor Ts [tsf]. 1 193 43.726 T 11-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_1681 4a7206e57565e5dd38fbdcf6fd9e9195 193 SUPERFAMILY SSF46934 1 50 7.55E-15 T 11-10-2018 IPR009060 UBA-like superfamily GO:0005515 TO73_1681 4a7206e57565e5dd38fbdcf6fd9e9195 193 Gene3D G3DSA:1.10.8.10 1 51 2.7E-22 T 11-10-2018 TO73_1681 4a7206e57565e5dd38fbdcf6fd9e9195 193 ProSitePatterns PS01126 Elongation factor Ts signature 1. 7 22 - T 11-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 SUPERFAMILY SSF52172 1 121 1.71E-33 T 11-10-2018 IPR011006 CheY-like superfamily TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 Pfam PF00072 Response regulator receiver domain 3 113 2.1E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 SUPERFAMILY SSF46894 120 191 1.67E-20 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 SMART SM00448 1 113 4.5E-35 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 Pfam PF00196 Bacterial regulatory proteins, luxR family 130 183 6.2E-19 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 Gene3D G3DSA:3.40.50.2300 1 128 5.0E-35 T 11-10-2018 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 SMART SM00421 128 185 6.1E-22 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 131 145 6.7E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 161 6.7E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 173 6.7E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TO73_1115 98a9a0ffe16bc74d1f5188c4c184a8fc 192 Gene3D G3DSA:1.10.10.10 129 191 1.0E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1927 f2315896b8d6c0dd49620bd7751ec60e 226 Pfam PF04493 Endonuclease V 21 215 2.8E-58 T 11-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TO73_1927 f2315896b8d6c0dd49620bd7751ec60e 226 Gene3D G3DSA:3.30.2170.10 5 226 1.1E-61 T 11-10-2018 TO73_1927 f2315896b8d6c0dd49620bd7751ec60e 226 Hamap MF_00801 Endonuclease V [nfi]. 11 225 32.561 T 11-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TO73_2289 bd41c1678b4b0554d2baa4af780e728b 229 SUPERFAMILY SSF51161 4 154 5.96E-47 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily TO73_2289 bd41c1678b4b0554d2baa4af780e728b 229 Gene3D G3DSA:2.160.10.10 2 165 9.8E-58 T 11-10-2018 TO73_2289 bd41c1678b4b0554d2baa4af780e728b 229 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 4.9E-8 T 11-10-2018 IPR001451 Hexapeptide repeat TO73_2289 bd41c1678b4b0554d2baa4af780e728b 229 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 45 2.2E-4 T 11-10-2018 IPR001451 Hexapeptide repeat TO73_2282 9e8bb595d9530c3c1a7f604d64a6bdfb 144 Pfam PF00582 Universal stress protein family 1 142 4.4E-35 T 11-10-2018 IPR006016 UspA TO73_2282 9e8bb595d9530c3c1a7f604d64a6bdfb 144 Gene3D G3DSA:3.40.50.620 1 142 1.2E-41 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_2282 9e8bb595d9530c3c1a7f604d64a6bdfb 144 SUPERFAMILY SSF52402 2 142 5.56E-41 T 11-10-2018 TO73_2282 9e8bb595d9530c3c1a7f604d64a6bdfb 144 PRINTS PR01438 Universal stress protein signature 120 142 6.4E-21 T 11-10-2018 IPR006015 Universal stress protein A TO73_2282 9e8bb595d9530c3c1a7f604d64a6bdfb 144 PRINTS PR01438 Universal stress protein signature 102 114 6.4E-21 T 11-10-2018 IPR006015 Universal stress protein A TO73_2282 9e8bb595d9530c3c1a7f604d64a6bdfb 144 PRINTS PR01438 Universal stress protein signature 2 20 6.4E-21 T 11-10-2018 IPR006015 Universal stress protein A TO73_0346 a96c52e8d1eabfb6688ee399946f14c1 173 SUPERFAMILY SSF46785 1 81 9.98E-7 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0213 2f67b59ba0f94e6faf0dd190a4fd0639 218 Pfam PF01551 Peptidase family M23 38 142 1.5E-17 T 11-10-2018 IPR016047 Peptidase M23 TO73_0213 2f67b59ba0f94e6faf0dd190a4fd0639 218 Gene3D G3DSA:2.70.70.10 12 151 2.0E-20 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_0213 2f67b59ba0f94e6faf0dd190a4fd0639 218 SUPERFAMILY SSF51261 36 143 1.05E-19 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_0547 57d20ea96ad6a0921932c55a515973d1 193 Pfam PF01553 Acyltransferase 25 131 7.7E-12 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TO73_0547 57d20ea96ad6a0921932c55a515973d1 193 SUPERFAMILY SSF69593 14 136 1.31E-18 T 11-10-2018 TO73_0547 57d20ea96ad6a0921932c55a515973d1 193 SMART SM00563 27 136 1.4E-23 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TO73_0876 2a8527fcd5181428eb0ffd9a5f96c4e7 216 Pfam PF14824 Sirohaem biosynthesis protein central 119 145 1.8E-6 T 11-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TO73_0876 2a8527fcd5181428eb0ffd9a5f96c4e7 216 Pfam PF13241 Putative NAD(P)-binding 6 115 7.2E-18 T 11-10-2018 TO73_0876 2a8527fcd5181428eb0ffd9a5f96c4e7 216 Pfam PF10414 Sirohaem synthase dimerisation region 150 191 7.6E-6 T 11-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TO73_0876 2a8527fcd5181428eb0ffd9a5f96c4e7 216 Gene3D G3DSA:3.40.50.720 3 130 5.9E-30 T 11-10-2018 TO73_0876 2a8527fcd5181428eb0ffd9a5f96c4e7 216 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 189 1.6E-40 T 11-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TO73_0876 2a8527fcd5181428eb0ffd9a5f96c4e7 216 Gene3D G3DSA:1.10.8.610 131 193 1.7E-5 T 11-10-2018 TO73_0876 2a8527fcd5181428eb0ffd9a5f96c4e7 216 SUPERFAMILY SSF51735 1 109 1.51E-20 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0876 2a8527fcd5181428eb0ffd9a5f96c4e7 216 SUPERFAMILY SSF75615 114 190 3.53E-19 T 11-10-2018 TO73_1094 77f100fb2def62bfb7412d6b701c3c26 424 SUPERFAMILY SSF53383 2 424 5.76E-131 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1094 77f100fb2def62bfb7412d6b701c3c26 424 Pfam PF00202 Aminotransferase class-III 38 393 3.0E-73 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_1094 77f100fb2def62bfb7412d6b701c3c26 424 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 422 5.4E-179 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 TO73_1094 77f100fb2def62bfb7412d6b701c3c26 424 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 271 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TO73_1094 77f100fb2def62bfb7412d6b701c3c26 424 Gene3D G3DSA:3.90.1150.10 10 419 3.5E-178 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1094 77f100fb2def62bfb7412d6b701c3c26 424 Gene3D G3DSA:3.40.640.10 71 319 3.5E-178 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1094 77f100fb2def62bfb7412d6b701c3c26 424 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 424 100.345 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 TO73_2346 eae4842ef62ab5413bf2d2d76e020e7a 116 SUPERFAMILY SSF54913 1 112 1.46E-37 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TO73_2346 eae4842ef62ab5413bf2d2d76e020e7a 116 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 11-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 TO73_2346 eae4842ef62ab5413bf2d2d76e020e7a 116 Gene3D G3DSA:3.30.70.120 1 116 1.4E-43 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TO73_2346 eae4842ef62ab5413bf2d2d76e020e7a 116 PRINTS PR00340 P-II protein signature 23 41 3.4E-24 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TO73_2346 eae4842ef62ab5413bf2d2d76e020e7a 116 PRINTS PR00340 P-II protein signature 52 75 3.4E-24 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TO73_2346 eae4842ef62ab5413bf2d2d76e020e7a 116 PRINTS PR00340 P-II protein signature 2 17 3.4E-24 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TO73_2346 eae4842ef62ab5413bf2d2d76e020e7a 116 PRINTS PR00340 P-II protein signature 83 103 3.4E-24 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TO73_2346 eae4842ef62ab5413bf2d2d76e020e7a 116 SMART SM00938 4 105 3.0E-44 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TO73_2346 eae4842ef62ab5413bf2d2d76e020e7a 116 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.8E-35 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TO73_1719 79948da39f9d8d0c0f74f60c8f3c08f2 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 45 156 8.0E-14 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TO73_1719 79948da39f9d8d0c0f74f60c8f3c08f2 361 SUPERFAMILY SSF50129 29 194 1.18E-25 T 11-10-2018 IPR011032 GroES-like superfamily TO73_1719 79948da39f9d8d0c0f74f60c8f3c08f2 361 Pfam PF00107 Zinc-binding dehydrogenase 196 328 4.0E-17 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TO73_1719 79948da39f9d8d0c0f74f60c8f3c08f2 361 Gene3D G3DSA:3.40.50.720 174 313 6.7E-61 T 11-10-2018 TO73_1719 79948da39f9d8d0c0f74f60c8f3c08f2 361 Gene3D G3DSA:3.90.180.10 45 350 6.7E-61 T 11-10-2018 TO73_1719 79948da39f9d8d0c0f74f60c8f3c08f2 361 SUPERFAMILY SSF51735 162 330 1.84E-21 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0035 6702743840142695f93fb5a4c925444e 429 SUPERFAMILY SSF53850 34 407 1.04E-70 T 11-10-2018 TO73_0035 6702743840142695f93fb5a4c925444e 429 Gene3D G3DSA:3.40.190.10 146 420 6.2E-91 T 11-10-2018 TO73_0035 6702743840142695f93fb5a4c925444e 429 Pfam PF13416 Bacterial extracellular solute-binding protein 51 368 5.1E-30 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein TO73_0035 6702743840142695f93fb5a4c925444e 429 Gene3D G3DSA:3.40.190.10 58 379 6.2E-91 T 11-10-2018 TO73_0758 deb489c7254adf24cc35728bc9aeb729 312 SUPERFAMILY SSF53474 103 309 1.04E-28 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0758 deb489c7254adf24cc35728bc9aeb729 312 Pfam PF00756 Putative esterase 114 307 3.5E-21 T 11-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TO73_0758 deb489c7254adf24cc35728bc9aeb729 312 Gene3D G3DSA:3.40.50.1820 89 311 3.6E-38 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0973 d77b7dcc42d8766b5ea6a1872dd7bc76 98 SMART SM00418 3 86 8.2E-6 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_0973 d77b7dcc42d8766b5ea6a1872dd7bc76 98 Gene3D G3DSA:1.10.10.10 1 98 2.3E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0973 d77b7dcc42d8766b5ea6a1872dd7bc76 98 Pfam PF01638 HxlR-like helix-turn-helix 7 94 3.0E-22 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type TO73_0973 d77b7dcc42d8766b5ea6a1872dd7bc76 98 SUPERFAMILY SSF46785 2 96 2.77E-28 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1630 33a0129a282f9f5ce75031ef6b38f712 418 Pfam PF03129 Anticodon binding domain 328 414 1.2E-11 T 11-10-2018 IPR004154 Anticodon-binding TO73_1630 33a0129a282f9f5ce75031ef6b38f712 418 Gene3D G3DSA:3.40.50.800 322 415 6.9E-21 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily TO73_1630 33a0129a282f9f5ce75031ef6b38f712 418 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 2 405 1.1E-136 T 11-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TO73_1630 33a0129a282f9f5ce75031ef6b38f712 418 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 415 30.794 T 11-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TO73_1630 33a0129a282f9f5ce75031ef6b38f712 418 Pfam PF13393 Histidyl-tRNA synthetase 5 309 7.9E-39 T 11-10-2018 TO73_1630 33a0129a282f9f5ce75031ef6b38f712 418 Gene3D G3DSA:3.30.930.10 1 321 4.9E-104 T 11-10-2018 TO73_1630 33a0129a282f9f5ce75031ef6b38f712 418 PIRSF PIRSF001549 1 415 7.5E-105 T 11-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TO73_1630 33a0129a282f9f5ce75031ef6b38f712 418 SUPERFAMILY SSF52954 325 414 1.8E-19 T 11-10-2018 TO73_1630 33a0129a282f9f5ce75031ef6b38f712 418 SUPERFAMILY SSF55681 3 313 5.77E-91 T 11-10-2018 TO73_1357 2cf059e1f7f6cc1577ace24621d953b9 103 Gene3D G3DSA:3.40.1350.90 1 103 6.2E-48 T 11-10-2018 TO73_1357 2cf059e1f7f6cc1577ace24621d953b9 103 Pfam PF11572 Protein of unknown function (DUF3234) 6 97 2.1E-37 T 11-10-2018 IPR021628 Protein of unknown function DUF3234 TO73_0922 b6c27a3524a0527c76eee110fd7a007c 130 Pfam PF03061 Thioesterase superfamily 39 110 3.9E-17 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TO73_0922 b6c27a3524a0527c76eee110fd7a007c 130 SUPERFAMILY SSF54637 7 124 5.15E-30 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_0922 b6c27a3524a0527c76eee110fd7a007c 130 Gene3D G3DSA:3.10.129.10 1 122 8.9E-34 T 11-10-2018 TO73_0922 b6c27a3524a0527c76eee110fd7a007c 130 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 9 108 2.9E-21 T 11-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TO73_0004 b876208304ba87b228ab135a55b6828b 474 Gene3D G3DSA:3.40.1380.20 336 469 5.9E-183 T 11-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 Gene3D G3DSA:3.20.20.60 5 335 5.9E-183 T 11-10-2018 TO73_0004 b876208304ba87b228ab135a55b6828b 474 SUPERFAMILY SSF50800 73 168 7.85E-28 T 11-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TO73_0004 b876208304ba87b228ab135a55b6828b 474 SUPERFAMILY SSF52935 323 473 3.27E-42 T 11-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.2E-68 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.2E-68 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.2E-68 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 PRINTS PR01050 Pyruvate kinase family signature 62 78 1.2E-68 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.2E-68 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 PRINTS PR01050 Pyruvate kinase family signature 187 201 1.2E-68 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.2E-68 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 473 3.7E-171 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 Gene3D G3DSA:2.40.33.10 73 169 5.9E-183 T 11-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 470 5.3E-34 T 11-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 Pfam PF00224 Pyruvate kinase, barrel domain 5 338 8.8E-129 T 11-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 11-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TO73_0004 b876208304ba87b228ab135a55b6828b 474 SUPERFAMILY SSF51621 4 339 1.51E-101 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TO73_0098 797a43f2ca490ee270a9310f233d0126 281 Gene3D G3DSA:3.30.1490.20 104 172 1.0E-29 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TO73_0098 797a43f2ca490ee270a9310f233d0126 281 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 2 279 4.7E-125 T 11-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 TO73_0098 797a43f2ca490ee270a9310f233d0126 281 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 275 1.2E-106 T 11-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 TO73_0098 797a43f2ca490ee270a9310f233d0126 281 Gene3D G3DSA:3.30.470.80 173 281 2.8E-42 T 11-10-2018 TO73_0098 797a43f2ca490ee270a9310f233d0126 281 SUPERFAMILY SSF56059 89 276 2.53E-46 T 11-10-2018 TO73_0098 797a43f2ca490ee270a9310f233d0126 281 Pfam PF08443 RimK-like ATP-grasp domain 88 274 4.6E-30 T 11-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 TO73_0098 797a43f2ca490ee270a9310f233d0126 281 SUPERFAMILY SSF52440 1 88 1.32E-22 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TO73_0098 797a43f2ca490ee270a9310f233d0126 281 Gene3D G3DSA:3.40.50.20 1 103 2.0E-31 T 11-10-2018 TO73_1785 1b2b61f3e1ce1255e3999b4fb2224198 100 SUPERFAMILY SSF54913 1 98 2.61E-24 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TO73_1785 1b2b61f3e1ce1255e3999b4fb2224198 100 Gene3D G3DSA:3.30.70.120 2 100 1.3E-32 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TO73_2104 83a45a2fb3e2c6349d129d5d85051c14 439 SUPERFAMILY SSF161098 88 438 3.05E-51 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2104 83a45a2fb3e2c6349d129d5d85051c14 439 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 252 430 2.6E-19 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1520 20ecc9aeb5bf126a771f2349638f6cef 176 Pfam PF05685 Putative restriction endonuclease 9 169 4.6E-26 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1520 20ecc9aeb5bf126a771f2349638f6cef 176 SUPERFAMILY SSF52980 8 147 3.54E-18 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1520 20ecc9aeb5bf126a771f2349638f6cef 176 Gene3D G3DSA:3.90.1570.10 2 168 3.9E-12 T 11-10-2018 TO73_2045 cd2326b74da47ced995d7264008df4f5 347 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 343 3.5E-67 T 11-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 TO73_1599 aa096e578d5ccbe1eb1f0f2819a9af5e 649 Pfam PF01496 V-type ATPase 116kDa subunit family 212 429 5.1E-13 T 11-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TO73_1599 aa096e578d5ccbe1eb1f0f2819a9af5e 649 Gene3D G3DSA:3.30.70.2170 2 46 1.0E-14 T 11-10-2018 TO73_1599 aa096e578d5ccbe1eb1f0f2819a9af5e 649 Gene3D G3DSA:3.30.70.2170 231 300 5.5E-24 T 11-10-2018 TO73_1599 aa096e578d5ccbe1eb1f0f2819a9af5e 649 Gene3D G3DSA:1.20.1460.20 47 135 1.3E-32 T 11-10-2018 TO73_1599 aa096e578d5ccbe1eb1f0f2819a9af5e 649 Gene3D G3DSA:3.30.70.2750 136 203 2.0E-28 T 11-10-2018 TO73_1422 71aaaa4f3dd18fe40234af1a6dfb56dc 225 SUPERFAMILY SSF47162 9 93 9.15E-7 T 11-10-2018 TO73_1422 71aaaa4f3dd18fe40234af1a6dfb56dc 225 Pfam PF07798 Protein of unknown function (DUF1640) 36 103 4.4E-6 T 11-10-2018 IPR024461 Coiled-coil domain-containing protein 90-like TO73_1422 71aaaa4f3dd18fe40234af1a6dfb56dc 225 Gene3D G3DSA:1.20.5.1230 23 215 1.0E-17 T 11-10-2018 TO73_1422 71aaaa4f3dd18fe40234af1a6dfb56dc 225 SUPERFAMILY SSF58113 74 206 1.7E-12 T 11-10-2018 TO73_1365 0f683e795c0296121aba36515f533a5e 332 SUPERFAMILY SSF88723 142 264 2.05E-21 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_1365 0f683e795c0296121aba36515f533a5e 332 SMART SM00670 140 244 1.6E-6 T 11-10-2018 IPR002716 PIN domain TO73_1365 0f683e795c0296121aba36515f533a5e 332 Gene3D G3DSA:3.40.50.1010 136 268 2.0E-44 T 11-10-2018 TO73_2081 3b9ea02053e886a6d4e92a3118bf3ab8 142 SUPERFAMILY SSF82784 3 138 4.84E-40 T 11-10-2018 IPR036102 OsmC/Ohr superfamily TO73_2081 3b9ea02053e886a6d4e92a3118bf3ab8 142 Gene3D G3DSA:3.30.300.20 1 142 1.4E-44 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_2081 3b9ea02053e886a6d4e92a3118bf3ab8 142 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 139 4.1E-55 T 11-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 TO73_2081 3b9ea02053e886a6d4e92a3118bf3ab8 142 Pfam PF02566 OsmC-like protein 40 136 4.6E-20 T 11-10-2018 IPR003718 OsmC/Ohr family TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 Gene3D G3DSA:3.60.20.40 347 524 1.5E-58 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 SUPERFAMILY SSF56235 3 524 5.4E-165 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 125 144 2.2E-41 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 107 125 2.2E-41 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 228 244 2.2E-41 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 370 388 2.2E-41 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 257 276 2.2E-41 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 42 67 2.2E-41 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 425 442 2.2E-41 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 401 416 2.2E-41 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 Pfam PF01019 Gamma-glutamyltranspeptidase 35 520 3.2E-143 T 11-10-2018 TO73_1263 0c8fe465a9820d121b4c40de9902440f 525 Gene3D G3DSA:1.10.246.130 244 346 1.1E-25 T 11-10-2018 TO73_1656 d1a2ff9b580478231517c3412513653b 345 Gene3D G3DSA:3.90.230.10 118 343 1.3E-85 T 11-10-2018 TO73_1656 d1a2ff9b580478231517c3412513653b 345 Pfam PF00557 Metallopeptidase family M24 127 329 2.3E-69 T 11-10-2018 IPR000994 Peptidase M24 TO73_1656 d1a2ff9b580478231517c3412513653b 345 PRINTS PR00599 Methionine aminopeptidase-1 signature 297 309 3.6E-6 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TO73_1656 d1a2ff9b580478231517c3412513653b 345 PRINTS PR00599 Methionine aminopeptidase-1 signature 199 215 3.6E-6 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TO73_1656 d1a2ff9b580478231517c3412513653b 345 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 275 287 - T 11-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TO73_1656 d1a2ff9b580478231517c3412513653b 345 SUPERFAMILY SSF55920 120 344 3.93E-81 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like TO73_1656 d1a2ff9b580478231517c3412513653b 345 Gene3D G3DSA:3.40.350.10 4 117 1.9E-23 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TO73_1656 d1a2ff9b580478231517c3412513653b 345 SUPERFAMILY SSF53092 6 118 6.8E-21 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TO73_1656 d1a2ff9b580478231517c3412513653b 345 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 118 2.3E-20 T 11-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TO73_0263 efa2acae56836c9e53bdcac845ad60d5 336 Gene3D G3DSA:3.40.50.2000 156 327 6.3E-73 T 11-10-2018 TO73_0263 efa2acae56836c9e53bdcac845ad60d5 336 Pfam PF13439 Glycosyltransferase Family 4 22 160 2.1E-10 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TO73_0263 efa2acae56836c9e53bdcac845ad60d5 336 SUPERFAMILY SSF53756 9 335 1.36E-51 T 11-10-2018 TO73_0263 efa2acae56836c9e53bdcac845ad60d5 336 Pfam PF00534 Glycosyl transferases group 1 165 313 3.7E-18 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 TO73_0263 efa2acae56836c9e53bdcac845ad60d5 336 Gene3D G3DSA:3.40.50.2000 12 333 6.3E-73 T 11-10-2018 TO73_0742 872eaf7b3fc75bc29d32f9526a89d02d 163 SUPERFAMILY SSF103196 6 134 1.2E-27 T 11-10-2018 TO73_0742 872eaf7b3fc75bc29d32f9526a89d02d 163 Pfam PF03259 Roadblock/LC7 domain 19 109 1.9E-19 T 11-10-2018 IPR004942 Roadblock/LAMTOR2 domain TO73_0742 872eaf7b3fc75bc29d32f9526a89d02d 163 SMART SM00960 18 109 1.1E-11 T 11-10-2018 IPR004942 Roadblock/LAMTOR2 domain TO73_0742 872eaf7b3fc75bc29d32f9526a89d02d 163 Gene3D G3DSA:3.30.450.30 1 138 1.9E-41 T 11-10-2018 TO73_2111 8f40f998fe8b2c1817e15d29105e03ff 150 SUPERFAMILY SSF52788 1 130 3.4E-35 T 11-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TO73_2111 8f40f998fe8b2c1817e15d29105e03ff 150 Gene3D G3DSA:3.40.50.2300 1 127 4.8E-37 T 11-10-2018 TO73_2111 8f40f998fe8b2c1817e15d29105e03ff 150 SMART SM00226 1 132 9.0E-29 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TO73_2111 8f40f998fe8b2c1817e15d29105e03ff 150 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 124 2.7E-20 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TO73_1531 de37de19fdacbe189a4aac959da1c899 250 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 185 201 - T 11-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TO73_1531 de37de19fdacbe189a4aac959da1c899 250 Pfam PF01026 TatD related DNase 2 248 1.4E-57 T 11-10-2018 IPR001130 TatD family GO:0016788 TO73_1531 de37de19fdacbe189a4aac959da1c899 250 SUPERFAMILY SSF51556 1 249 8.27E-62 T 11-10-2018 IPR032466 Metal-dependent hydrolase TO73_1531 de37de19fdacbe189a4aac959da1c899 250 Gene3D G3DSA:3.20.20.140 1 249 1.2E-65 T 11-10-2018 TO73_1531 de37de19fdacbe189a4aac959da1c899 250 PIRSF PIRSF005902 1 250 1.2E-51 T 11-10-2018 IPR001130 TatD family GO:0016788 TO73_1510 511dd57dccf125ec68ea05472542ffbd 210 SUPERFAMILY SSF53474 18 196 1.6E-17 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_1510 511dd57dccf125ec68ea05472542ffbd 210 Gene3D G3DSA:3.40.50.1820 16 197 2.7E-17 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_1510 511dd57dccf125ec68ea05472542ffbd 210 Pfam PF12697 Alpha/beta hydrolase family 18 190 8.1E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_1377 8c84b329b98bfcf35892f662c2f1d7b6 805 Gene3D G3DSA:3.30.70.2230 519 698 1.5E-25 T 11-10-2018 TO73_1377 8c84b329b98bfcf35892f662c2f1d7b6 805 TIGRFAM TIGR02578 cas_TM1811_Csm1: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE 8 690 1.7E-158 T 11-10-2018 IPR013408 CRISPR-associated protein Csm1 TO73_1377 8c84b329b98bfcf35892f662c2f1d7b6 805 Pfam PF01966 HD domain 7 97 7.9E-8 T 11-10-2018 IPR006674 HD domain TO73_1377 8c84b329b98bfcf35892f662c2f1d7b6 805 Gene3D G3DSA:1.10.3210.10 3 116 2.4E-8 T 11-10-2018 TO73_1377 8c84b329b98bfcf35892f662c2f1d7b6 805 SUPERFAMILY SSF109604 8 97 2.1E-6 T 11-10-2018 TO73_0982 8d74728d78fbb690d7cf7f2d0a48610f 222 Gene3D G3DSA:3.30.70.1900 108 219 2.0E-21 T 11-10-2018 TO73_0982 8d74728d78fbb690d7cf7f2d0a48610f 222 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 33 217 3.8E-29 T 11-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TO73_0982 8d74728d78fbb690d7cf7f2d0a48610f 222 PIRSF PIRSF005054 1 221 1.8E-43 T 11-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TO73_0982 8d74728d78fbb690d7cf7f2d0a48610f 222 Gene3D G3DSA:3.30.70.1890 1 102 4.4E-5 T 11-10-2018 TO73_0982 8d74728d78fbb690d7cf7f2d0a48610f 222 Pfam PF01881 CRISPR associated protein Cas6 82 217 1.4E-25 T 11-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TO73_0045 9a69008c40eee9a32bce09c0a6ce8d53 268 SUPERFAMILY SSF52402 1 150 6.87E-22 T 11-10-2018 TO73_0045 9a69008c40eee9a32bce09c0a6ce8d53 268 SUPERFAMILY SSF52402 158 268 2.76E-15 T 11-10-2018 TO73_0045 9a69008c40eee9a32bce09c0a6ce8d53 268 Pfam PF00582 Universal stress protein family 2 147 3.9E-16 T 11-10-2018 IPR006016 UspA TO73_0045 9a69008c40eee9a32bce09c0a6ce8d53 268 Gene3D G3DSA:3.40.50.12370 1 268 2.8E-84 T 11-10-2018 TO73_1490 9ee64ad0de817fd5ab84c470f9b93409 181 Pfam PF00156 Phosphoribosyl transferase domain 8 162 4.7E-21 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TO73_1490 9ee64ad0de817fd5ab84c470f9b93409 181 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 38.454 T 11-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TO73_1490 9ee64ad0de817fd5ab84c470f9b93409 181 Gene3D G3DSA:3.40.50.2020 1 181 1.8E-64 T 11-10-2018 TO73_1490 9ee64ad0de817fd5ab84c470f9b93409 181 SUPERFAMILY SSF53271 6 172 1.31E-44 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_1268 697f0f1458dbf2bcf75c796672e39d80 342 SUPERFAMILY SSF81345 6 338 3.4E-80 T 11-10-2018 IPR037294 ABC transporter, BtuC-like TO73_1268 697f0f1458dbf2bcf75c796672e39d80 342 Pfam PF01032 FecCD transport family 21 337 1.5E-86 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TO73_1268 697f0f1458dbf2bcf75c796672e39d80 342 Gene3D G3DSA:1.10.3470.10 9 341 3.1E-94 T 11-10-2018 IPR037294 ABC transporter, BtuC-like TO73_1400 20eca36173e62a0dc597b3791778ff19 88 Pfam PF00708 Acylphosphatase 6 85 5.2E-29 T 11-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TO73_1400 20eca36173e62a0dc597b3791778ff19 88 SUPERFAMILY SSF54975 2 87 1.48E-28 T 11-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TO73_1400 20eca36173e62a0dc597b3791778ff19 88 Gene3D G3DSA:3.30.70.100 1 88 1.9E-35 T 11-10-2018 TO73_1642 f0cae2c9f6917337f3d903d01734f282 506 Gene3D G3DSA:3.40.50.720 26 269 4.6E-42 T 11-10-2018 TO73_1642 f0cae2c9f6917337f3d903d01734f282 506 SUPERFAMILY SSF55961 353 492 9.7E-9 T 11-10-2018 TO73_1642 f0cae2c9f6917337f3d903d01734f282 506 Pfam PF13460 NAD(P)H-binding 31 158 2.0E-17 T 11-10-2018 IPR016040 NAD(P)-binding domain TO73_1642 f0cae2c9f6917337f3d903d01734f282 506 SUPERFAMILY SSF51735 26 312 1.81E-46 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_1642 f0cae2c9f6917337f3d903d01734f282 506 Pfam PF11066 Protein of unknown function (DUF2867) 351 481 2.9E-27 T 11-10-2018 IPR021295 Protein of unknown function DUF2867 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 SMART SM01192 138 420 8.7E-222 T 11-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 Gene3D G3DSA:3.30.390.10 1 126 1.5E-51 T 11-10-2018 IPR029017 Enolase-like, N-terminal TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 Pfam PF03952 Enolase, N-terminal domain 4 133 5.4E-55 T 11-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 420 3.4E-207 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 SUPERFAMILY SSF54826 1 136 3.24E-53 T 11-10-2018 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 SUPERFAMILY SSF51604 139 421 3.01E-130 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 Gene3D G3DSA:3.20.20.120 127 422 1.3E-135 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 Hamap MF_00318 Enolase [eno]. 2 410 46.2 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 ProSitePatterns PS00164 Enolase signature. 333 346 - T 11-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 419 8.2E-131 T 11-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 PRINTS PR00148 Enolase signature 37 51 9.7E-48 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 PRINTS PR00148 Enolase signature 362 379 9.7E-48 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 PRINTS PR00148 Enolase signature 333 347 9.7E-48 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 PRINTS PR00148 Enolase signature 310 321 9.7E-48 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 PRINTS PR00148 Enolase signature 106 122 9.7E-48 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 PRINTS PR00148 Enolase signature 160 173 9.7E-48 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 PIRSF PIRSF001400 1 422 4.1E-188 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_0003 d0147696bc1e4ac0432a138e5b29cd12 422 SMART SM01193 4 133 8.8E-89 T 11-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TO73_1718 125d7828ad89ff9c625b77ceb58bb15b 353 SMART SM01007 185 343 8.1E-5 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal TO73_1718 125d7828ad89ff9c625b77ceb58bb15b 353 SUPERFAMILY SSF53639 193 343 9.61E-24 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TO73_1718 125d7828ad89ff9c625b77ceb58bb15b 353 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 196 283 5.0E-11 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal TO73_1718 125d7828ad89ff9c625b77ceb58bb15b 353 Gene3D G3DSA:3.40.225.10 188 346 2.1E-22 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TO73_1573 421171ced1e897f215878418687bc895 212 Pfam PF04098 Rad52/22 family double-strand break repair protein 4 133 3.6E-17 T 11-10-2018 IPR007232 DNA repair protein Rad52/59/22 GO:0006281|GO:0006310 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938 TO73_1573 421171ced1e897f215878418687bc895 212 Gene3D G3DSA:3.30.390.80 2 133 2.3E-5 T 11-10-2018 TO73_0556 acde338c82281660a1cd27e36a38f476 199 Gene3D G3DSA:3.30.70.60 82 188 2.8E-6 T 11-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TO73_0556 acde338c82281660a1cd27e36a38f476 199 Pfam PF04350 Pilus assembly protein, PilO 45 179 4.0E-8 T 11-10-2018 IPR007445 Pilus assembly protein, PilO TO73_0173 5029225e89eedfb6b35e095f16e7254c 77 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 10 55 5.0E-12 T 11-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TO73_0173 5029225e89eedfb6b35e095f16e7254c 77 SUPERFAMILY SSF46955 8 54 1.76E-7 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily TO73_0173 5029225e89eedfb6b35e095f16e7254c 77 Pfam PF12728 Helix-turn-helix domain 8 56 2.5E-14 T 11-10-2018 TO73_0173 5029225e89eedfb6b35e095f16e7254c 77 Gene3D G3DSA:1.10.1660.10 3 57 1.4E-8 T 11-10-2018 TO73_0896 975e7ce8f46dadbd1f2bd66e97777455 243 SUPERFAMILY SSF103481 41 137 8.5E-8 T 11-10-2018 TO73_0896 975e7ce8f46dadbd1f2bd66e97777455 243 Pfam PF00892 EamA-like transporter family 10 134 4.0E-15 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_0848 737ec30b3cb58e6ba2473d628d2e1398 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 278 1.0E-86 T 11-10-2018 IPR003797 DegV TO73_0848 737ec30b3cb58e6ba2473d628d2e1398 280 Gene3D G3DSA:3.40.50.10170 1 150 1.6E-56 T 11-10-2018 TO73_0848 737ec30b3cb58e6ba2473d628d2e1398 280 Gene3D G3DSA:3.30.1180.10 151 280 5.1E-46 T 11-10-2018 TO73_0848 737ec30b3cb58e6ba2473d628d2e1398 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 277 4.4E-93 T 11-10-2018 IPR003797 DegV TO73_0848 737ec30b3cb58e6ba2473d628d2e1398 280 SUPERFAMILY SSF82549 1 278 8.63E-85 T 11-10-2018 TO73_2841 bd45dca1498596418e9131cfb05a22ff 137 Gene3D G3DSA:3.40.50.1010 6 128 1.1E-11 T 11-10-2018 TO73_2841 bd45dca1498596418e9131cfb05a22ff 137 Pfam PF01850 PIN domain 7 122 2.5E-6 T 11-10-2018 IPR002716 PIN domain TO73_2841 bd45dca1498596418e9131cfb05a22ff 137 SUPERFAMILY SSF88723 6 133 1.93E-18 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_1796 74015fe9ad912512e341d48939c75c20 510 Gene3D G3DSA:3.30.9.10 99 334 5.7E-110 T 11-10-2018 TO73_1796 74015fe9ad912512e341d48939c75c20 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 95 107 4.1E-28 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TO73_1796 74015fe9ad912512e341d48939c75c20 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 354 366 4.1E-28 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TO73_1796 74015fe9ad912512e341d48939c75c20 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 327 333 4.1E-28 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TO73_1796 74015fe9ad912512e341d48939c75c20 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 27 37 4.1E-28 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TO73_1796 74015fe9ad912512e341d48939c75c20 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 43 55 4.1E-28 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TO73_1796 74015fe9ad912512e341d48939c75c20 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 14 26 4.1E-28 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TO73_1796 74015fe9ad912512e341d48939c75c20 510 Gene3D G3DSA:3.50.50.60 15 373 5.7E-110 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1796 74015fe9ad912512e341d48939c75c20 510 SUPERFAMILY SSF54373 245 333 5.1E-7 T 11-10-2018 TO73_1796 74015fe9ad912512e341d48939c75c20 510 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 390 494 1.6E-26 T 11-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TO73_1796 74015fe9ad912512e341d48939c75c20 510 Pfam PF01266 FAD dependent oxidoreductase 15 370 9.9E-48 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TO73_1796 74015fe9ad912512e341d48939c75c20 510 Gene3D G3DSA:1.10.8.870 399 508 1.5E-31 T 11-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TO73_1796 74015fe9ad912512e341d48939c75c20 510 SUPERFAMILY SSF51905 9 234 2.02E-33 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_0671 4d365012b33ccc4c485ceafeb0ca2cbf 249 Gene3D G3DSA:3.40.50.1820 54 206 2.0E-12 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0671 4d365012b33ccc4c485ceafeb0ca2cbf 249 Pfam PF12695 Alpha/beta hydrolase family 67 223 6.4E-48 T 11-10-2018 IPR029059 Alpha/beta hydrolase fold-5 TO73_0671 4d365012b33ccc4c485ceafeb0ca2cbf 249 SUPERFAMILY SSF53474 60 208 1.2E-16 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_2090 660d6a130bb54a8dd92cd62ddf4bdaf2 126 SUPERFAMILY SSF89360 7 100 9.61E-30 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TO73_2090 660d6a130bb54a8dd92cd62ddf4bdaf2 126 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 95 112 - T 11-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 TO73_2090 660d6a130bb54a8dd92cd62ddf4bdaf2 126 Gene3D G3DSA:2.60.300.12 8 116 9.9E-36 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TO73_2090 660d6a130bb54a8dd92cd62ddf4bdaf2 126 Pfam PF01521 Iron-sulphur cluster biosynthesis 9 109 8.3E-18 T 11-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 TO73_2090 660d6a130bb54a8dd92cd62ddf4bdaf2 126 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 9 113 2.7E-36 T 11-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 TO73_1114 a79918f8f13bd49f318892453bf9b674 286 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 16 282 1.6E-78 T 11-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 TO73_1114 a79918f8f13bd49f318892453bf9b674 286 Pfam PF03313 Serine dehydratase alpha chain 17 268 1.0E-68 T 11-10-2018 IPR005130 Serine dehydratase-like, alpha subunit TO73_1114 a79918f8f13bd49f318892453bf9b674 286 SUPERFAMILY SSF103378 108 239 7.06E-6 T 11-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 TO73_0283 b65be4f04842e3ec4a2dc5b773cf9cb0 93 SUPERFAMILY SSF103247 17 66 3.4E-6 T 11-10-2018 IPR035923 TT1751-like domain superfamily TO73_0283 b65be4f04842e3ec4a2dc5b773cf9cb0 93 Gene3D G3DSA:3.30.310.70 16 82 3.1E-12 T 11-10-2018 IPR035923 TT1751-like domain superfamily TO73_1328 68007ec5c0a02a12d15bae48e413523c 227 Gene3D G3DSA:3.40.50.10320 1 227 6.9E-90 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TO73_1328 68007ec5c0a02a12d15bae48e413523c 227 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 121 5.9E-22 T 11-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TO73_1328 68007ec5c0a02a12d15bae48e413523c 227 SUPERFAMILY SSF102588 2 220 1.06E-57 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TO73_1328 68007ec5c0a02a12d15bae48e413523c 227 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 2 216 1.1E-63 T 11-10-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 TO73_2397 cde02811425fd45d4e6a6d455f74824c 285 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 10 261 8.3E-17 T 11-10-2018 IPR024455 Phage capsid TO73_2397 cde02811425fd45d4e6a6d455f74824c 285 SUPERFAMILY SSF56563 5 253 1.01E-23 T 11-10-2018 TO73_2397 cde02811425fd45d4e6a6d455f74824c 285 Pfam PF05065 Phage capsid family 48 226 3.6E-15 T 11-10-2018 IPR024455 Phage capsid TO73_0269 36c1e5843680c393ecd55a74432fed00 139 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 7 138 2.0E-44 T 11-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TO73_0269 36c1e5843680c393ecd55a74432fed00 139 Gene3D G3DSA:3.55.10.10 3 139 4.7E-36 T 11-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TO73_0269 36c1e5843680c393ecd55a74432fed00 139 Pfam PF01951 Archease protein family (MTH1598/TM1083) 6 139 1.9E-32 T 11-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TO73_0269 36c1e5843680c393ecd55a74432fed00 139 SUPERFAMILY SSF69819 4 139 3.14E-35 T 11-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TO73_0660 596dfb8289ec56042fc9448c4b718c4a 398 Pfam PF13458 Periplasmic binding protein 26 376 7.7E-51 T 11-10-2018 IPR028081 Leucine-binding protein domain TO73_0660 596dfb8289ec56042fc9448c4b718c4a 398 Gene3D G3DSA:3.40.50.2300 29 345 1.1E-101 T 11-10-2018 TO73_0660 596dfb8289ec56042fc9448c4b718c4a 398 Gene3D G3DSA:3.40.50.2300 136 274 1.1E-101 T 11-10-2018 TO73_0660 596dfb8289ec56042fc9448c4b718c4a 398 SUPERFAMILY SSF53822 25 382 2.83E-47 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_2862 28816505bc2a5505cc3a7534d0c90d16 176 SUPERFAMILY SSF53098 4 137 4.93E-12 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2862 28816505bc2a5505cc3a7534d0c90d16 176 Gene3D G3DSA:3.30.420.10 2 142 7.2E-11 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_1638 e65ebbfa5ea4e808df7fc0b46b1c49e8 177 SUPERFAMILY SSF50475 3 159 2.49E-25 T 11-10-2018 TO73_1638 e65ebbfa5ea4e808df7fc0b46b1c49e8 177 Gene3D G3DSA:2.30.110.10 2 160 1.6E-28 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TO73_1638 e65ebbfa5ea4e808df7fc0b46b1c49e8 177 SMART SM00903 6 152 0.0014 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TO73_1638 e65ebbfa5ea4e808df7fc0b46b1c49e8 177 Pfam PF01613 Flavin reductase like domain 18 154 2.5E-11 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TO73_0614 fb1cac1be43918780599acd2c3703593 325 Gene3D G3DSA:3.40.190.10 24 322 3.3E-89 T 11-10-2018 TO73_0614 fb1cac1be43918780599acd2c3703593 325 SUPERFAMILY SSF53850 21 324 3.53E-56 T 11-10-2018 TO73_0614 fb1cac1be43918780599acd2c3703593 325 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 5 322 1.9E-77 T 11-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TO73_0614 fb1cac1be43918780599acd2c3703593 325 Gene3D G3DSA:3.40.190.10 112 257 3.3E-89 T 11-10-2018 TO73_0614 fb1cac1be43918780599acd2c3703593 325 Pfam PF16868 NMT1-like family 24 322 2.2E-69 T 11-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TO73_0236 c16d4abe4aaabeee8bb5804315c476e8 166 Pfam PF00583 Acetyltransferase (GNAT) family 53 140 9.8E-8 T 11-10-2018 IPR000182 GNAT domain TO73_0236 c16d4abe4aaabeee8bb5804315c476e8 166 SUPERFAMILY SSF55729 4 146 2.44E-25 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_0236 c16d4abe4aaabeee8bb5804315c476e8 166 Gene3D G3DSA:3.40.630.30 1 157 1.4E-38 T 11-10-2018 TO73_1881 470163e3903097330c8861d1f679a43b 569 Gene3D G3DSA:3.50.50.60 14 174 7.9E-13 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1881 470163e3903097330c8861d1f679a43b 569 SUPERFAMILY SSF51905 17 407 1.14E-21 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TO73_1881 470163e3903097330c8861d1f679a43b 569 Pfam PF12831 FAD dependent oxidoreductase 19 408 2.9E-77 T 11-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal TO73_1119 26bfb99bf74e49886d6845fccb1fe0e6 72 SUPERFAMILY SSF54814 15 61 6.54E-7 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TO73_1119 26bfb99bf74e49886d6845fccb1fe0e6 72 Gene3D G3DSA:3.30.300.20 3 70 1.5E-8 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta TO73_1119 26bfb99bf74e49886d6845fccb1fe0e6 72 Hamap MF_00088 UPF0109 protein . 1 72 18.285 T 11-10-2018 IPR020627 Uncharacterised protein family UPF0109 TO73_1119 26bfb99bf74e49886d6845fccb1fe0e6 72 Pfam PF13083 KH domain 2 66 1.7E-19 T 11-10-2018 TO73_2746 33364b81ab0ad8b1a1452cd05e06124b 624 SUPERFAMILY SSF52743 171 444 5.63E-62 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_2746 33364b81ab0ad8b1a1452cd05e06124b 624 Pfam PF00082 Subtilase family 189 424 8.6E-32 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TO73_2746 33364b81ab0ad8b1a1452cd05e06124b 624 PRINTS PR00723 Subtilisin serine protease family (S8) signature 407 423 9.5E-16 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_2746 33364b81ab0ad8b1a1452cd05e06124b 624 PRINTS PR00723 Subtilisin serine protease family (S8) signature 233 246 9.5E-16 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_2746 33364b81ab0ad8b1a1452cd05e06124b 624 PRINTS PR00723 Subtilisin serine protease family (S8) signature 189 208 9.5E-16 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related TO73_2746 33364b81ab0ad8b1a1452cd05e06124b 624 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 408 418 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TO73_2746 33364b81ab0ad8b1a1452cd05e06124b 624 Gene3D G3DSA:3.40.50.200 164 461 4.2E-68 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TO73_1048 6934dc6bfb257e59afb6437253624e98 223 Pfam PF03167 Uracil DNA glycosylase superfamily 48 213 2.4E-33 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TO73_1048 6934dc6bfb257e59afb6437253624e98 223 SUPERFAMILY SSF52141 17 219 6.54E-49 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TO73_1048 6934dc6bfb257e59afb6437253624e98 223 SMART SM00987 48 214 1.0E-30 T 11-10-2018 TO73_1048 6934dc6bfb257e59afb6437253624e98 223 SMART SM00986 48 214 1.0E-30 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TO73_1048 6934dc6bfb257e59afb6437253624e98 223 Gene3D G3DSA:3.40.470.10 5 223 5.5E-74 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TO73_1725 61342f46c37a662be2b18683afcf0138 443 SUPERFAMILY SSF52096 46 370 5.96E-66 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_1725 61342f46c37a662be2b18683afcf0138 443 Gene3D G3DSA:2.30.42.10 103 193 1.4E-88 T 11-10-2018 TO73_1725 61342f46c37a662be2b18683afcf0138 443 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 103 173 4.1E-12 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_1725 61342f46c37a662be2b18683afcf0138 443 SMART SM00228 103 177 2.5E-16 T 11-10-2018 IPR001478 PDZ domain GO:0005515 TO73_1725 61342f46c37a662be2b18683afcf0138 443 Gene3D G3DSA:3.30.750.44 46 341 1.4E-88 T 11-10-2018 TO73_1725 61342f46c37a662be2b18683afcf0138 443 Pfam PF03572 Peptidase family S41 203 365 1.1E-51 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TO73_1725 61342f46c37a662be2b18683afcf0138 443 SUPERFAMILY SSF50156 75 198 1.97E-22 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 TO73_1725 61342f46c37a662be2b18683afcf0138 443 SMART SM00245 179 366 3.0E-57 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TO73_1725 61342f46c37a662be2b18683afcf0138 443 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 52 371 3.9E-84 T 11-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 TO73_1725 61342f46c37a662be2b18683afcf0138 443 Gene3D G3DSA:3.90.226.10 194 363 1.4E-88 T 11-10-2018 TO73_2187 d3ee6e532fca1f90b8d1fb1da76ccc71 396 PRINTS PR00758 Arsenical pump membrane protein signature 105 129 5.7E-8 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TO73_2187 d3ee6e532fca1f90b8d1fb1da76ccc71 396 PRINTS PR00758 Arsenical pump membrane protein signature 269 293 5.7E-8 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TO73_2187 d3ee6e532fca1f90b8d1fb1da76ccc71 396 Pfam PF03600 Citrate transporter 29 335 6.5E-28 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TO73_1870 cbe621ff718eda6d5554a99e5c20d1e2 174 Gene3D G3DSA:2.40.380.10 61 166 4.5E-9 T 11-10-2018 IPR035930 FomD-like superfamily TO73_1870 cbe621ff718eda6d5554a99e5c20d1e2 174 SUPERFAMILY SSF159234 25 163 3.53E-19 T 11-10-2018 IPR035930 FomD-like superfamily TO73_1870 cbe621ff718eda6d5554a99e5c20d1e2 174 Pfam PF04167 Protein of unknown function (DUF402) 65 128 2.2E-10 T 11-10-2018 IPR007295 Domain of unknown function DUF402 TO73_2058 a089971658087d5dc61fdbeef0aecf3c 79 SUPERFAMILY SSF52833 3 75 1.33E-10 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_2058 a089971658087d5dc61fdbeef0aecf3c 79 Pfam PF05768 Glutaredoxin-like domain (DUF836) 3 53 2.0E-7 T 11-10-2018 IPR008554 Glutaredoxin-like TO73_2058 a089971658087d5dc61fdbeef0aecf3c 79 Gene3D G3DSA:3.40.30.10 2 75 9.6E-11 T 11-10-2018 TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 Gene3D G3DSA:3.40.50.620 1 160 1.3E-56 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 Pfam PF01467 Cytidylyltransferase-like 4 134 2.8E-21 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 158 2.9E-59 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 1 159 36.027 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 SUPERFAMILY SSF52374 2 157 6.44E-45 T 11-10-2018 TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 64 7.0E-16 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 1.1E-40 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.1E-40 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 1.1E-40 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TO73_1084 a1bedcffe6e07098206e8636f5de6125 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 1 19 1.1E-40 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TO73_1871 93a1357bb6e2510088e7019928858b6b 63 Pfam PF11127 Protein of unknown function (DUF2892) 1 62 2.5E-21 T 11-10-2018 IPR021309 Protein of unknown function DUF2892 TO73_2103 369cd3f4e3360072a3b14283999ffd26 442 SUPERFAMILY SSF161098 189 429 4.06E-55 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2103 369cd3f4e3360072a3b14283999ffd26 442 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 225 429 2.1E-23 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_2103 369cd3f4e3360072a3b14283999ffd26 442 Gene3D G3DSA:1.10.3720.10 185 440 1.2E-63 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2103 369cd3f4e3360072a3b14283999ffd26 442 SUPERFAMILY SSF160964 18 184 5.62E-23 T 11-10-2018 TO73_0861 7febccfb123f0d97b341b441c3f12a4a 331 Gene3D G3DSA:3.90.1150.10 20 322 2.8E-60 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_0861 7febccfb123f0d97b341b441c3f12a4a 331 Gene3D G3DSA:3.40.640.10 32 235 2.8E-60 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_0861 7febccfb123f0d97b341b441c3f12a4a 331 SUPERFAMILY SSF53383 15 326 4.92E-50 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_0861 7febccfb123f0d97b341b441c3f12a4a 331 Pfam PF00155 Aminotransferase class I and II 46 322 2.2E-26 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TO73_0249 df96acd2d0f872b497a8458fca98e381 145 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 13 134 4.2E-25 T 11-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TO73_0249 df96acd2d0f872b497a8458fca98e381 145 SUPERFAMILY SSF52540 26 92 4.39E-16 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0249 df96acd2d0f872b497a8458fca98e381 145 Gene3D G3DSA:3.40.50.300 3 143 8.2E-31 T 11-10-2018 TO73_0249 df96acd2d0f872b497a8458fca98e381 145 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 11 112 5.7E-28 T 11-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TO73_2320 a1a345a74f4560f414fb363a48b4464b 381 Gene3D G3DSA:3.40.720.10 2 380 4.2E-142 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TO73_2320 a1a345a74f4560f414fb363a48b4464b 381 SUPERFAMILY SSF53649 1 381 5.82E-64 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TO73_2320 a1a345a74f4560f414fb363a48b4464b 381 Hamap MF_00740 Phosphopentomutase [deoB]. 1 381 44.91 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TO73_2320 a1a345a74f4560f414fb363a48b4464b 381 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 378 2.4E-124 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TO73_2320 a1a345a74f4560f414fb363a48b4464b 381 SUPERFAMILY SSF143856 96 213 1.57E-42 T 11-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TO73_2320 a1a345a74f4560f414fb363a48b4464b 381 Gene3D G3DSA:3.30.70.1250 94 213 4.2E-142 T 11-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TO73_2320 a1a345a74f4560f414fb363a48b4464b 381 Pfam PF01676 Metalloenzyme superfamily 1 371 1.6E-25 T 11-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TO73_2320 a1a345a74f4560f414fb363a48b4464b 381 PIRSF PIRSF001491 1 381 7.7E-139 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TO73_1313 653e0382b906083f33db2707f1f153bb 219 SMART SM01133 2 213 2.3E-75 T 11-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TO73_1313 653e0382b906083f33db2707f1f153bb 219 Pfam PF01791 DeoC/LacD family aldolase 14 210 2.0E-11 T 11-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TO73_1313 653e0382b906083f33db2707f1f153bb 219 PIRSF PIRSF001357 1 219 9.9E-69 T 11-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TO73_1313 653e0382b906083f33db2707f1f153bb 219 Gene3D G3DSA:3.20.20.70 1 218 9.1E-85 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1313 653e0382b906083f33db2707f1f153bb 219 SUPERFAMILY SSF51569 1 213 1.15E-70 T 11-10-2018 TO73_1313 653e0382b906083f33db2707f1f153bb 219 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 215 32.24 T 11-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 TO73_1313 653e0382b906083f33db2707f1f153bb 219 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 210 1.6E-64 T 11-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TO73_0095 7c267816e68826f9f0e3abc8014cc0ee 163 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 1 159 31.539 T 11-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 TO73_0095 7c267816e68826f9f0e3abc8014cc0ee 163 SUPERFAMILY SSF52016 3 158 1.1E-40 T 11-10-2018 TO73_0095 7c267816e68826f9f0e3abc8014cc0ee 163 Pfam PF00694 Aconitase C-terminal domain 48 103 7.6E-18 T 11-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TO73_0095 7c267816e68826f9f0e3abc8014cc0ee 163 Gene3D G3DSA:3.20.19.10 2 160 5.6E-46 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TO73_0095 7c267816e68826f9f0e3abc8014cc0ee 163 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 3 156 1.8E-49 T 11-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 TO73_2742 b103a2390af7852bebd8a11c707a717c 1214 Pfam PF02384 N-6 DNA Methylase 497 788 1.3E-20 T 11-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TO73_2742 b103a2390af7852bebd8a11c707a717c 1214 Gene3D G3DSA:3.40.50.150 497 805 5.8E-46 T 11-10-2018 TO73_2742 b103a2390af7852bebd8a11c707a717c 1214 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 708 732 9.8E-19 T 11-10-2018 TO73_2742 b103a2390af7852bebd8a11c707a717c 1214 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 545 559 9.8E-19 T 11-10-2018 TO73_2742 b103a2390af7852bebd8a11c707a717c 1214 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 665 677 9.8E-19 T 11-10-2018 TO73_2742 b103a2390af7852bebd8a11c707a717c 1214 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 517 533 9.8E-19 T 11-10-2018 TO73_2742 b103a2390af7852bebd8a11c707a717c 1214 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 668 674 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TO73_2742 b103a2390af7852bebd8a11c707a717c 1214 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 50 134 1.6E-6 T 11-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain TO73_2742 b103a2390af7852bebd8a11c707a717c 1214 SUPERFAMILY SSF53335 392 790 5.97E-56 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_0710 1f6beecea6ea5daa33f97c4a71b45ae1 422 Gene3D G3DSA:2.40.50.140 358 422 9.2E-6 T 11-10-2018 TO73_0710 1f6beecea6ea5daa33f97c4a71b45ae1 422 Gene3D G3DSA:3.90.226.10 16 225 8.9E-46 T 11-10-2018 TO73_0710 1f6beecea6ea5daa33f97c4a71b45ae1 422 Pfam PF01957 NfeD-like C-terminal, partner-binding 277 418 3.4E-11 T 11-10-2018 IPR002810 NfeD-like, C-terminal domain TO73_0710 1f6beecea6ea5daa33f97c4a71b45ae1 422 Pfam PF01972 Serine dehydrogenase proteinase 53 126 7.9E-5 T 11-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 TO73_0710 1f6beecea6ea5daa33f97c4a71b45ae1 422 SUPERFAMILY SSF52096 14 188 7.46E-22 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_0295 5671e3676b379860bd578cb24ca8fd9a 439 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 17 254 3.0E-102 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TO73_0295 5671e3676b379860bd578cb24ca8fd9a 439 SUPERFAMILY SSF51621 11 433 9.42E-158 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TO73_0295 5671e3676b379860bd578cb24ca8fd9a 439 Pfam PF00463 Isocitrate lyase family 258 433 2.7E-51 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TO73_0295 5671e3676b379860bd578cb24ca8fd9a 439 Pfam PF00463 Isocitrate lyase family 20 254 5.6E-62 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TO73_0295 5671e3676b379860bd578cb24ca8fd9a 439 PIRSF PIRSF001362 7 436 8.7E-238 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TO73_0295 5671e3676b379860bd578cb24ca8fd9a 439 ProSitePatterns PS00161 Isocitrate lyase signature. 193 198 - T 11-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 TO73_0295 5671e3676b379860bd578cb24ca8fd9a 439 Gene3D G3DSA:3.20.20.60 12 416 3.3E-174 T 11-10-2018 TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 Pfam PF00850 Histone deacetylase domain 16 304 4.9E-72 T 11-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 SUPERFAMILY SSF52768 1 326 2.35E-97 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 77 91 1.9E-17 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 10 30 1.9E-17 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 98 111 1.9E-17 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 338 357 1.9E-17 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 PRINTS PR01270 Histone deacetylase superfamily signature 238 248 4.3E-19 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 PRINTS PR01270 Histone deacetylase superfamily signature 120 143 4.3E-19 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 PRINTS PR01270 Histone deacetylase superfamily signature 152 167 4.3E-19 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_1859 5de6b9967b5d1c0f8390fef83fcfec99 374 Gene3D G3DSA:3.40.800.20 1 330 1.9E-98 T 11-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TO73_1877 98fa72e010b201d5ae1df06819f25544 132 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 127 11.287 T 11-10-2018 IPR022907 VapC family GO:0004540 TO73_1877 98fa72e010b201d5ae1df06819f25544 132 Pfam PF01850 PIN domain 5 120 1.9E-10 T 11-10-2018 IPR002716 PIN domain TO73_1877 98fa72e010b201d5ae1df06819f25544 132 Gene3D G3DSA:3.40.50.1010 3 123 1.9E-25 T 11-10-2018 TO73_1877 98fa72e010b201d5ae1df06819f25544 132 SUPERFAMILY SSF88723 4 126 8.69E-16 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_1544 caf6371750ea762834e5b3fd526cc4a9 208 Pfam PF00156 Phosphoribosyl transferase domain 8 191 5.3E-29 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TO73_1544 caf6371750ea762834e5b3fd526cc4a9 208 Gene3D G3DSA:3.30.1310.20 53 113 3.9E-76 T 11-10-2018 TO73_1544 caf6371750ea762834e5b3fd526cc4a9 208 SUPERFAMILY SSF53271 1 203 7.08E-51 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_1544 caf6371750ea762834e5b3fd526cc4a9 208 Gene3D G3DSA:3.40.50.2020 3 200 3.9E-76 T 11-10-2018 TO73_2362 a51a1c675a6ea3831659892ce5f19417 187 Gene3D G3DSA:1.20.1200.10 12 187 2.3E-65 T 11-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TO73_2362 a51a1c675a6ea3831659892ce5f19417 187 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 181 4.0E-77 T 11-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TO73_2362 a51a1c675a6ea3831659892ce5f19417 187 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 181 3.1E-65 T 11-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TO73_2362 a51a1c675a6ea3831659892ce5f19417 187 Pfam PF01923 Cobalamin adenosyltransferase 3 170 1.9E-65 T 11-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TO73_2362 a51a1c675a6ea3831659892ce5f19417 187 SUPERFAMILY SSF89028 1 182 1.18E-66 T 11-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TO73_0986 7d23fe29515b35fbab7ef513c6dab9df 185 Gene3D G3DSA:1.10.357.10 39 174 3.2E-39 T 11-10-2018 TO73_0986 7d23fe29515b35fbab7ef513c6dab9df 185 SUPERFAMILY SSF46689 2 59 9.75E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_0986 7d23fe29515b35fbab7ef513c6dab9df 185 SUPERFAMILY SSF48498 64 175 1.28E-25 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TO73_0986 7d23fe29515b35fbab7ef513c6dab9df 185 Gene3D G3DSA:1.10.10.60 1 38 5.6E-12 T 11-10-2018 TO73_0986 7d23fe29515b35fbab7ef513c6dab9df 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 44 9.2E-13 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TO73_0518 926ada0c390f94b48988b5dd5f5c7a83 143 Pfam PF00581 Rhodanese-like domain 56 133 1.4E-12 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_0518 926ada0c390f94b48988b5dd5f5c7a83 143 SUPERFAMILY SSF52821 40 140 4.45E-29 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_0518 926ada0c390f94b48988b5dd5f5c7a83 143 SMART SM00450 42 138 6.2E-17 T 11-10-2018 IPR001763 Rhodanese-like domain TO73_0518 926ada0c390f94b48988b5dd5f5c7a83 143 Gene3D G3DSA:3.40.250.10 42 141 3.4E-25 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_0353 3baf7360e398b11214186e4cba26f9c7 228 SUPERFAMILY SSF55469 89 227 1.96E-15 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TO73_0353 3baf7360e398b11214186e4cba26f9c7 228 Pfam PF00881 Nitroreductase family 89 227 7.4E-13 T 11-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TO73_0353 3baf7360e398b11214186e4cba26f9c7 228 Gene3D G3DSA:3.40.109.10 10 228 1.2E-40 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TO73_1826 7982246eaa3b8559b9a730afc1508e3f 132 Gene3D G3DSA:1.10.10.1100 66 127 2.9E-11 T 11-10-2018 TO73_2324 0ec5d2ffa6015dffe7a78e10112d6c7e 161 SUPERFAMILY SSF109854 4 159 1.83E-26 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TO73_2324 0ec5d2ffa6015dffe7a78e10112d6c7e 161 Pfam PF12867 DinB superfamily 14 158 4.4E-19 T 11-10-2018 IPR024775 DinB-like domain TO73_1408 ff6ebf0602ed841a63f95294aa36f9d7 87 Pfam PF10387 Protein of unknown function (DUF2442) 3 74 8.2E-14 T 11-10-2018 IPR018841 Protein of unknown function DUF2442 TO73_1408 ff6ebf0602ed841a63f95294aa36f9d7 87 SUPERFAMILY SSF143880 2 77 1.09E-16 T 11-10-2018 IPR036782 NE0471-like, N-terminal TO73_1408 ff6ebf0602ed841a63f95294aa36f9d7 87 Gene3D G3DSA:3.30.2020.10 2 76 1.1E-5 T 11-10-2018 IPR036782 NE0471-like, N-terminal TO73_1585 a926515503f38c831b06f5804c4c8a00 177 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 15 156 9.9E-28 T 11-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1585 a926515503f38c831b06f5804c4c8a00 177 Gene3D G3DSA:1.20.120.1200 3 160 7.5E-48 T 11-10-2018 TO73_0599 a9b82641b5fcfcaef75e8f7f52be36c3 237 SUPERFAMILY SSF52540 3 235 6.99E-65 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0599 a9b82641b5fcfcaef75e8f7f52be36c3 237 SMART SM00382 28 228 1.5E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0599 a9b82641b5fcfcaef75e8f7f52be36c3 237 Gene3D G3DSA:3.40.50.300 2 237 1.8E-67 T 11-10-2018 TO73_0599 a9b82641b5fcfcaef75e8f7f52be36c3 237 PIRSF PIRSF039137 1 237 8.8E-114 T 11-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 TO73_0599 a9b82641b5fcfcaef75e8f7f52be36c3 237 Pfam PF00005 ABC transporter 19 164 1.1E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0599 a9b82641b5fcfcaef75e8f7f52be36c3 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1497 092873dbaa96e4fc746f1756f4105a99 186 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 186 20.974 T 11-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 TO73_1497 092873dbaa96e4fc746f1756f4105a99 186 Pfam PF12804 MobA-like NTP transferase domain 5 142 6.5E-33 T 11-10-2018 IPR025877 MobA-like NTP transferase TO73_1497 092873dbaa96e4fc746f1756f4105a99 186 Gene3D G3DSA:3.90.550.10 2 186 6.1E-44 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1497 092873dbaa96e4fc746f1756f4105a99 186 SUPERFAMILY SSF53448 1 185 3.03E-33 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1381 c4ce1330d8df1eae85af23a82b609736 375 Pfam PF03787 RAMP superfamily 11 331 4.9E-8 T 11-10-2018 IPR005537 CRISPR type III-associated RAMP protein TO73_1381 c4ce1330d8df1eae85af23a82b609736 375 TIGRFAM TIGR01899 cas_TM1807_csm5: CRISPR type III-A/MTUBE-associated RAMP protein Csm5 10 336 2.8E-15 T 11-10-2018 IPR010173 CRISPR-associated protein, TM1807 TO73_2266 e971de73a2be1652338f3d1b93d39dd7 230 Pfam PF12146 Serine aminopeptidase, S33 3 210 1.1E-17 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 TO73_2266 e971de73a2be1652338f3d1b93d39dd7 230 SUPERFAMILY SSF53474 3 222 5.03E-34 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_2266 e971de73a2be1652338f3d1b93d39dd7 230 Gene3D G3DSA:3.40.50.1820 2 223 1.1E-48 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_2266 e971de73a2be1652338f3d1b93d39dd7 230 PIRSF PIRSF017388 1 226 3.8E-42 T 11-10-2018 IPR012354 Esterase/lipase GO:0052689 TO73_1068 99e9bbdf8603f26eca26b5efebe891a5 398 Gene3D G3DSA:3.40.50.2000 5 187 5.3E-35 T 11-10-2018 TO73_1068 99e9bbdf8603f26eca26b5efebe891a5 398 SUPERFAMILY SSF53756 8 373 6.52E-82 T 11-10-2018 TO73_1068 99e9bbdf8603f26eca26b5efebe891a5 398 Gene3D G3DSA:3.40.50.2000 192 355 1.6E-43 T 11-10-2018 TO73_1068 99e9bbdf8603f26eca26b5efebe891a5 398 Pfam PF00534 Glycosyl transferases group 1 192 353 3.7E-39 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 TO73_1068 99e9bbdf8603f26eca26b5efebe891a5 398 Pfam PF13439 Glycosyltransferase Family 4 18 179 1.3E-31 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TO73_1371 98b1552c7f6194eb2251d4e10c69ad72 285 SUPERFAMILY SSF103481 38 139 1.96E-17 T 11-10-2018 TO73_1371 98b1552c7f6194eb2251d4e10c69ad72 285 Pfam PF00892 EamA-like transporter family 147 281 2.9E-27 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_1371 98b1552c7f6194eb2251d4e10c69ad72 285 Pfam PF00892 EamA-like transporter family 5 136 5.2E-24 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_1371 98b1552c7f6194eb2251d4e10c69ad72 285 SUPERFAMILY SSF103481 181 283 4.32E-19 T 11-10-2018 TO73_0294 2825034b4aa23805874da8f435820cbc 932 Gene3D G3DSA:1.25.40.10 423 608 2.4E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0294 2825034b4aa23805874da8f435820cbc 932 Pfam PF13181 Tetratricopeptide repeat 654 682 0.005 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_0294 2825034b4aa23805874da8f435820cbc 932 SUPERFAMILY SSF48452 519 726 2.15E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0294 2825034b4aa23805874da8f435820cbc 932 Gene3D G3DSA:1.25.40.10 613 756 4.1E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0869 494a8bc3c80a69b4b4ad879f6ec8e3a5 187 SUPERFAMILY SSF52540 15 186 1.99E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0869 494a8bc3c80a69b4b4ad879f6ec8e3a5 187 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 16 187 1.2E-59 T 11-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TO73_0869 494a8bc3c80a69b4b4ad879f6ec8e3a5 187 Gene3D G3DSA:3.40.50.300 3 187 6.0E-66 T 11-10-2018 TO73_0869 494a8bc3c80a69b4b4ad879f6ec8e3a5 187 PIRSF PIRSF015617 2 187 4.4E-64 T 11-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TO73_0869 494a8bc3c80a69b4b4ad879f6ec8e3a5 187 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 18 186 2.2E-62 T 11-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TO73_0270 d7359f82b44ad72ee3ebb4c7e27a06a9 223 SUPERFAMILY SSF102588 2 220 6.15E-46 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TO73_0270 d7359f82b44ad72ee3ebb4c7e27a06a9 223 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 146 1.2E-26 T 11-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TO73_0270 d7359f82b44ad72ee3ebb4c7e27a06a9 223 Gene3D G3DSA:3.40.50.10320 3 213 5.3E-41 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 Pfam PF00875 DNA photolyase 3 151 1.8E-31 T 11-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 SUPERFAMILY SSF48173 162 412 9.03E-83 T 11-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 Gene3D G3DSA:1.10.579.10 257 417 2.0E-60 T 11-10-2018 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 Gene3D G3DSA:1.25.40.80 169 256 3.7E-28 T 11-10-2018 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 288 300 - T 11-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 Gene3D G3DSA:3.40.50.620 1 119 7.0E-42 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 PRINTS PR00147 DNA photolyase signature 308 326 2.6E-18 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 PRINTS PR00147 DNA photolyase signature 347 361 2.6E-18 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 PRINTS PR00147 DNA photolyase signature 288 304 2.6E-18 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 PRINTS PR00147 DNA photolyase signature 126 142 2.6E-18 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 SUPERFAMILY SSF52425 1 163 2.09E-37 T 11-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 TO73_1249 cdbfdafc08068dfba94d69c5cfeb7b50 417 Pfam PF03441 FAD binding domain of DNA photolyase 239 393 9.6E-57 T 11-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 TO73_1414 f76d9e45c053aa4d6c74196256c5fbe4 202 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 25 8.9E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1414 f76d9e45c053aa4d6c74196256c5fbe4 202 SUPERFAMILY SSF54523 5 63 2.75E-5 T 11-10-2018 TO73_1414 f76d9e45c053aa4d6c74196256c5fbe4 202 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 6.0E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_1414 f76d9e45c053aa4d6c74196256c5fbe4 202 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site TO73_0616 ab7f05b82eba2657625a0b72132b03d5 334 Gene3D G3DSA:3.40.190.10 30 331 3.5E-85 T 11-10-2018 TO73_0616 ab7f05b82eba2657625a0b72132b03d5 334 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 6 331 5.7E-71 T 11-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TO73_0616 ab7f05b82eba2657625a0b72132b03d5 334 Pfam PF16868 NMT1-like family 30 331 1.4E-59 T 11-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TO73_0616 ab7f05b82eba2657625a0b72132b03d5 334 Gene3D G3DSA:3.40.190.10 120 265 3.5E-85 T 11-10-2018 TO73_0616 ab7f05b82eba2657625a0b72132b03d5 334 SUPERFAMILY SSF53850 27 332 1.37E-54 T 11-10-2018 TO73_1650 9d690f21827a4cdb3ed43194d3f572d4 293 Pfam PF01680 SOR/SNZ family 6 211 6.8E-110 T 11-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_1650 9d690f21827a4cdb3ed43194d3f572d4 293 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 8 293 2.9E-151 T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_1650 9d690f21827a4cdb3ed43194d3f572d4 293 ProSitePatterns PS01235 PdxS/SNZ family signature. 204 222 - T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_1650 9d690f21827a4cdb3ed43194d3f572d4 293 PIRSF PIRSF029271 1 293 1.6E-156 T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_1650 9d690f21827a4cdb3ed43194d3f572d4 293 SUPERFAMILY SSF51366 17 266 1.93E-67 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TO73_1650 9d690f21827a4cdb3ed43194d3f572d4 293 Gene3D G3DSA:3.20.20.70 1 293 4.2E-154 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1650 9d690f21827a4cdb3ed43194d3f572d4 293 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 3 293 53.152 T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TO73_0727 2de9c586d59b32cb4ddd4989a406fb8f 310 Gene3D G3DSA:3.90.25.10 175 303 7.8E-126 T 11-10-2018 TO73_0727 2de9c586d59b32cb4ddd4989a406fb8f 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 9.1E-63 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TO73_0727 2de9c586d59b32cb4ddd4989a406fb8f 310 SUPERFAMILY SSF51735 1 309 9.3E-91 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0727 2de9c586d59b32cb4ddd4989a406fb8f 310 Gene3D G3DSA:3.40.50.720 3 243 7.8E-126 T 11-10-2018 TO73_2197 ac2608f2bfe9a03909b03b95091de654 414 SUPERFAMILY SSF53244 282 406 9.16E-20 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_2197 ac2608f2bfe9a03909b03b95091de654 414 Gene3D G3DSA:3.90.190.20 282 408 1.3E-20 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TO73_2197 ac2608f2bfe9a03909b03b95091de654 414 SUPERFAMILY SSF53623 3 277 1.96E-80 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_2197 ac2608f2bfe9a03909b03b95091de654 414 Gene3D G3DSA:3.40.1190.10 2 280 3.2E-88 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TO73_2197 ac2608f2bfe9a03909b03b95091de654 414 PIRSF PIRSF001563 1 408 1.6E-106 T 11-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TO73_2197 ac2608f2bfe9a03909b03b95091de654 414 Pfam PF08245 Mur ligase middle domain 40 260 1.0E-16 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TO73_2197 ac2608f2bfe9a03909b03b95091de654 414 TIGRFAM TIGR01499 folC: bifunctional protein FolC 18 403 3.4E-101 T 11-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TO73_2189 0bfdb645166b06d512585e1da6f13de5 347 SUPERFAMILY SSF53187 93 332 4.19E-20 T 11-10-2018 TO73_2189 0bfdb645166b06d512585e1da6f13de5 347 Pfam PF04389 Peptidase family M28 181 329 1.3E-11 T 11-10-2018 IPR007484 Peptidase M28 TO73_1858 6bf5ba71b89167aefc6988eeeacfed4c 65 Pfam PF02597 ThiS family 10 65 1.5E-5 T 11-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TO73_1858 6bf5ba71b89167aefc6988eeeacfed4c 65 SUPERFAMILY SSF54285 9 65 2.62E-10 T 11-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TO73_1858 6bf5ba71b89167aefc6988eeeacfed4c 65 Gene3D G3DSA:3.10.20.30 1 65 3.0E-17 T 11-10-2018 IPR012675 Beta-grasp domain superfamily TO73_0400 54ba34cc76b8377f8e56f94f18d8e82b 37 Pfam PF00444 Ribosomal protein L36 1 37 2.2E-22 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0400 54ba34cc76b8377f8e56f94f18d8e82b 37 SUPERFAMILY SSF57840 1 37 4.32E-18 T 11-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0400 54ba34cc76b8377f8e56f94f18d8e82b 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 19.022 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0400 54ba34cc76b8377f8e56f94f18d8e82b 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 4.0E-9 T 11-10-2018 TO73_0400 54ba34cc76b8377f8e56f94f18d8e82b 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0400 54ba34cc76b8377f8e56f94f18d8e82b 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 8.7E-24 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TO73_0895 dbe052efeb4f44847c8e0fb23a7e18a3 348 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 25 342 1.8E-44 T 11-10-2018 IPR007184 Mannoside phosphorylase TO73_0895 dbe052efeb4f44847c8e0fb23a7e18a3 348 SUPERFAMILY SSF75005 47 337 2.12E-23 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TO73_0895 dbe052efeb4f44847c8e0fb23a7e18a3 348 Gene3D G3DSA:2.115.10.20 39 346 2.5E-28 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TO73_2054 f9d396c9d42b6387cc9e693860457fdc 247 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 6 227 2.7E-60 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TO73_2054 f9d396c9d42b6387cc9e693860457fdc 247 Pfam PF00902 Sec-independent protein translocase protein (TatC) 8 222 1.2E-63 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TO73_2054 f9d396c9d42b6387cc9e693860457fdc 247 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 239 15.409 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TO73_2054 f9d396c9d42b6387cc9e693860457fdc 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 129 1.1E-35 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TO73_2054 f9d396c9d42b6387cc9e693860457fdc 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 1.1E-35 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TO73_2054 f9d396c9d42b6387cc9e693860457fdc 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 5 32 1.1E-35 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TO73_2054 f9d396c9d42b6387cc9e693860457fdc 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 85 103 1.1E-35 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 27 411 4.0E-140 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 412 38.876 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 SUPERFAMILY SSF53720 24 411 1.69E-72 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 PRINTS PR00083 Histidinol dehydrogenase signature 346 364 6.6E-78 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 PRINTS PR00083 Histidinol dehydrogenase signature 237 256 6.6E-78 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 PRINTS PR00083 Histidinol dehydrogenase signature 186 211 6.6E-78 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 PRINTS PR00083 Histidinol dehydrogenase signature 125 151 6.6E-78 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 PRINTS PR00083 Histidinol dehydrogenase signature 27 51 6.6E-78 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 PRINTS PR00083 Histidinol dehydrogenase signature 156 182 6.6E-78 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 PRINTS PR00083 Histidinol dehydrogenase signature 305 330 6.6E-78 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 PRINTS PR00083 Histidinol dehydrogenase signature 215 236 6.6E-78 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 Gene3D G3DSA:3.40.50.1980 219 334 2.9E-111 T 11-10-2018 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 PIRSF PIRSF000099 2 412 5.0E-146 T 11-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 Pfam PF00815 Histidinol dehydrogenase 21 411 3.8E-144 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TO73_1622 12ebe96e0f818fea4eb7fc4f3dff6145 412 Gene3D G3DSA:3.40.50.1980 24 218 2.9E-111 T 11-10-2018 TO73_2205 3b31e968900747c37e925bed379b946e 147 SUPERFAMILY SSF46785 8 144 1.01E-31 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_2205 3b31e968900747c37e925bed379b946e 147 Pfam PF01475 Ferric uptake regulator family 17 114 8.5E-26 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TO73_2205 3b31e968900747c37e925bed379b946e 147 Gene3D G3DSA:3.30.1490.190 90 147 8.5E-14 T 11-10-2018 TO73_2205 3b31e968900747c37e925bed379b946e 147 Gene3D G3DSA:1.10.10.10 3 87 1.5E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1888 a0f32f0660042f4444f2ddfd4de2ad30 105 Pfam PF07883 Cupin domain 33 100 2.0E-18 T 11-10-2018 IPR013096 Cupin 2, conserved barrel TO73_1888 a0f32f0660042f4444f2ddfd4de2ad30 105 SUPERFAMILY SSF51182 25 103 1.72E-19 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily TO73_1888 a0f32f0660042f4444f2ddfd4de2ad30 105 Gene3D G3DSA:2.60.120.10 1 105 6.8E-27 T 11-10-2018 IPR014710 RmlC-like jelly roll fold TO73_0424 2579e558febfa249ff49174d003c34e5 483 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 30 468 2.0E-85 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC TO73_0424 2579e558febfa249ff49174d003c34e5 483 Pfam PF10079 Bacillithiol biosynthesis BshC 30 468 4.5E-72 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC TO73_1276 f17fa18bea04f2ea07d9062ebd8ec4e0 290 Pfam PF00107 Zinc-binding dehydrogenase 125 234 1.8E-22 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TO73_1276 f17fa18bea04f2ea07d9062ebd8ec4e0 290 Gene3D G3DSA:3.40.50.720 98 258 9.9E-100 T 11-10-2018 TO73_1276 f17fa18bea04f2ea07d9062ebd8ec4e0 290 SUPERFAMILY SSF50129 2 119 1.48E-29 T 11-10-2018 IPR011032 GroES-like superfamily TO73_1276 f17fa18bea04f2ea07d9062ebd8ec4e0 290 Gene3D G3DSA:3.90.180.10 3 287 9.9E-100 T 11-10-2018 TO73_1276 f17fa18bea04f2ea07d9062ebd8ec4e0 290 SMART SM00829 1 288 2.1E-19 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TO73_1276 f17fa18bea04f2ea07d9062ebd8ec4e0 290 SUPERFAMILY SSF51735 87 244 1.67E-40 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_0300 cb9ab418130311394ba9feb31e030f8a 87 Pfam PF07978 NIPSNAP 1 83 6.3E-6 T 11-10-2018 IPR012577 NIPSNAP TO73_0300 cb9ab418130311394ba9feb31e030f8a 87 SUPERFAMILY SSF54909 1 83 1.03E-5 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel TO73_1338 327d2de59855f5332e45652832a4b666 526 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 9 25 - T 11-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1338 327d2de59855f5332e45652832a4b666 526 Pfam PF08502 LeuA allosteric (dimerisation) domain 392 513 2.9E-17 T 11-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1338 327d2de59855f5332e45652832a4b666 526 SUPERFAMILY SSF110921 398 509 1.7E-13 T 11-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1338 327d2de59855f5332e45652832a4b666 526 Gene3D G3DSA:3.20.20.70 1 280 1.1E-77 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_1338 327d2de59855f5332e45652832a4b666 526 Gene3D G3DSA:1.10.238.260 282 380 4.2E-27 T 11-10-2018 TO73_1338 327d2de59855f5332e45652832a4b666 526 Pfam PF00682 HMGL-like 2 250 1.2E-39 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TO73_1338 327d2de59855f5332e45652832a4b666 526 SUPERFAMILY SSF51569 2 291 2.01E-78 T 11-10-2018 TO73_1338 327d2de59855f5332e45652832a4b666 526 SMART SM00917 371 514 3.5E-31 T 11-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TO73_1338 327d2de59855f5332e45652832a4b666 526 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 2 515 5.9E-203 T 11-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 TO73_1781 ab99433a6b41115d664e12e04dfae2a0 294 SUPERFAMILY SSF53098 22 291 6.22E-56 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_0850 18bdf04d710a191657e17ba8355b398a 56 SUPERFAMILY SSF161098 3 51 2.83E-6 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0850 18bdf04d710a191657e17ba8355b398a 56 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 11 49 4.2E-7 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1039 3b28e88afc119ef873ca947362decd33 80 Pfam PF01568 Molydopterin dinucleotide binding domain 1 71 2.6E-24 T 11-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TO73_1039 3b28e88afc119ef873ca947362decd33 80 Gene3D G3DSA:2.40.40.20 1 80 3.4E-27 T 11-10-2018 TO73_1039 3b28e88afc119ef873ca947362decd33 80 SUPERFAMILY SSF50692 1 79 1.94E-29 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TO73_0794 f38bdb36e4303041e52d989ea5e87096 194 Gene3D G3DSA:3.60.20.10 15 191 1.3E-55 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_0794 f38bdb36e4303041e52d989ea5e87096 194 Pfam PF00227 Proteasome subunit 18 190 1.1E-19 T 11-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TO73_0794 f38bdb36e4303041e52d989ea5e87096 194 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 20 190 6.8E-71 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 TO73_0794 f38bdb36e4303041e52d989ea5e87096 194 SUPERFAMILY SSF56235 17 191 6.92E-51 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TO73_0619 4c119ed2fcd3b78f6863a8a5816763a8 372 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 355 1.7E-96 T 11-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TO73_0619 4c119ed2fcd3b78f6863a8a5816763a8 372 SUPERFAMILY SSF53756 1 365 1.48E-115 T 11-10-2018 TO73_0619 4c119ed2fcd3b78f6863a8a5816763a8 372 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 356 4.0E-113 T 11-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 TO73_0619 4c119ed2fcd3b78f6863a8a5816763a8 372 Gene3D G3DSA:3.40.50.2000 188 344 1.2E-133 T 11-10-2018 TO73_0619 4c119ed2fcd3b78f6863a8a5816763a8 372 Gene3D G3DSA:3.40.50.2000 6 349 1.2E-133 T 11-10-2018 TO73_0713 54061585be1bc36c72687d8bd1569c64 395 Pfam PF13173 AAA domain 27 152 2.3E-22 T 11-10-2018 TO73_0713 54061585be1bc36c72687d8bd1569c64 395 SUPERFAMILY SSF52540 13 175 9.47E-20 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0713 54061585be1bc36c72687d8bd1569c64 395 Gene3D G3DSA:3.40.50.300 1 117 1.2E-5 T 11-10-2018 TO73_0713 54061585be1bc36c72687d8bd1569c64 395 Pfam PF13635 Domain of unknown function (DUF4143) 197 353 3.3E-22 T 11-10-2018 IPR025420 Domain of unknown function DUF4143 TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 Gene3D G3DSA:3.40.50.720 1 261 2.0E-63 T 11-10-2018 TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 SUPERFAMILY SSF51735 8 257 6.51E-70 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 253 9.1E-84 T 11-10-2018 TO73_2327 305f38ba51fafd22b7f83cf61ab4daff 267 PIRSF PIRSF000094 3 261 2.7E-100 T 11-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 Pfam PF13432 Tetratricopeptide repeat 334 389 5.4E-5 T 11-10-2018 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 Pfam PF13432 Tetratricopeptide repeat 286 328 0.0035 T 11-10-2018 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 SUPERFAMILY SSF48452 361 543 1.99E-22 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 SUPERFAMILY SSF48452 237 388 2.86E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 SMART SM00028 297 330 81.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 SMART SM00028 399 432 490.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 SMART SM00028 477 510 9.7E-6 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 SMART SM00028 362 395 35.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 SMART SM00028 437 470 0.021 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 Gene3D G3DSA:1.25.40.10 223 399 4.6E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 Pfam PF13424 Tetratricopeptide repeat 437 508 8.6E-15 T 11-10-2018 TO73_2196 babe860bd6d93b83df5d8dfa9e331503 559 Gene3D G3DSA:1.25.40.10 400 559 1.7E-22 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0913 eba49734b9078920f085728eb8d274bd 428 Gene3D G3DSA:3.40.50.2300 150 302 8.7E-50 T 11-10-2018 TO73_0913 eba49734b9078920f085728eb8d274bd 428 Gene3D G3DSA:3.40.50.2300 41 374 8.7E-50 T 11-10-2018 TO73_0913 eba49734b9078920f085728eb8d274bd 428 Pfam PF13458 Periplasmic binding protein 27 372 3.1E-34 T 11-10-2018 IPR028081 Leucine-binding protein domain TO73_0913 eba49734b9078920f085728eb8d274bd 428 SUPERFAMILY SSF53822 21 398 1.95E-48 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_1159 03211ce853dfa0775a4dbb986f8f9a95 247 SMART SM00479 72 236 6.4E-35 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TO73_1159 03211ce853dfa0775a4dbb986f8f9a95 247 Pfam PF00929 Exonuclease 74 226 5.0E-27 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TO73_1159 03211ce853dfa0775a4dbb986f8f9a95 247 Gene3D G3DSA:3.30.420.10 67 233 1.2E-39 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_1159 03211ce853dfa0775a4dbb986f8f9a95 247 SUPERFAMILY SSF53098 68 233 3.76E-39 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_1229 307fa1c5f0b0faefab804eea018c6668 339 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 2 133 1.6E-28 T 11-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_1229 307fa1c5f0b0faefab804eea018c6668 339 SUPERFAMILY SSF53756 2 337 8.75E-75 T 11-10-2018 TO73_1229 307fa1c5f0b0faefab804eea018c6668 339 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 2 339 27.478 T 11-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_1229 307fa1c5f0b0faefab804eea018c6668 339 Gene3D G3DSA:3.40.50.2000 159 305 1.4E-79 T 11-10-2018 TO73_1229 307fa1c5f0b0faefab804eea018c6668 339 Gene3D G3DSA:3.40.50.2000 3 158 1.4E-79 T 11-10-2018 TO73_1229 307fa1c5f0b0faefab804eea018c6668 339 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 182 309 2.2E-23 T 11-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TO73_1396 efa3e756f44f66fa032db2ff11765c1d 373 SUPERFAMILY SSF50952 40 360 2.22E-39 T 11-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TO73_1396 efa3e756f44f66fa032db2ff11765c1d 373 Pfam PF07995 Glucose / Sorbosone dehydrogenase 51 359 3.8E-88 T 11-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TO73_1396 efa3e756f44f66fa032db2ff11765c1d 373 Gene3D G3DSA:2.120.10.30 41 373 9.3E-142 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TO73_1067 1ea86e138a8a7054607c93aa3e271587 270 SUPERFAMILY SSF53756 32 246 9.42E-6 T 11-10-2018 TO73_1636 f840377f0a4890926c0deba6cd7d95f9 286 SUPERFAMILY SSF51658 41 272 1.93E-20 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily TO73_1636 f840377f0a4890926c0deba6cd7d95f9 286 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 2 278 3.1E-48 T 11-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 TO73_1636 f840377f0a4890926c0deba6cd7d95f9 286 Pfam PF03851 UV-endonuclease UvdE 5 240 3.0E-46 T 11-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 TO73_1636 f840377f0a4890926c0deba6cd7d95f9 286 Gene3D G3DSA:3.20.20.150 1 278 1.6E-98 T 11-10-2018 TO73_2076 356f5768111207d6147f952b14bdb9ab 356 SUPERFAMILY SSF53383 13 354 4.65E-82 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_2076 356f5768111207d6147f952b14bdb9ab 356 Gene3D G3DSA:3.40.640.10 50 259 2.5E-99 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_2076 356f5768111207d6147f952b14bdb9ab 356 Gene3D G3DSA:3.90.1150.10 11 348 2.5E-99 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_2076 356f5768111207d6147f952b14bdb9ab 356 Pfam PF00155 Aminotransferase class I and II 29 349 6.0E-37 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TO73_2340 30970652729e601ce636dc1f029b9e67 216 SUPERFAMILY SSF53254 15 207 1.46E-36 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_2340 30970652729e601ce636dc1f029b9e67 216 Gene3D G3DSA:3.40.50.1240 15 212 5.7E-36 T 11-10-2018 IPR029033 Histidine phosphatase superfamily TO73_2340 30970652729e601ce636dc1f029b9e67 216 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 17 208 4.7E-40 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TO73_0123 b68f141f501ea749a003bf77f4a54728 99 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 9 92 1.0E-28 T 11-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 TO73_1992 ca6e8e0c9a00a68191caa5bbea22d192 194 Gene3D G3DSA:3.40.1280.10 1 194 4.5E-76 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TO73_1992 ca6e8e0c9a00a68191caa5bbea22d192 194 SUPERFAMILY SSF75217 7 189 7.19E-51 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases TO73_1992 ca6e8e0c9a00a68191caa5bbea22d192 194 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 5 194 35.543 T 11-10-2018 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 TO73_1992 ca6e8e0c9a00a68191caa5bbea22d192 194 Pfam PF12105 SpoU, rRNA methylase, C-terminal 166 188 9.4E-7 T 11-10-2018 IPR022724 RNA methyltransferase, SpoU/TrmH type, C-terminal GO:0009020 TO73_1992 ca6e8e0c9a00a68191caa5bbea22d192 194 Pfam PF00588 SpoU rRNA Methylase family 23 162 7.2E-36 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TO73_1441 ceb12d3b92113904e1c541944576ff08 267 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 220 3.6E-21 T 11-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TO73_1441 ceb12d3b92113904e1c541944576ff08 267 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 4 264 6.9E-118 T 11-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 TO73_1441 ceb12d3b92113904e1c541944576ff08 267 Gene3D G3DSA:3.40.50.300 3 255 3.6E-67 T 11-10-2018 TO73_1441 ceb12d3b92113904e1c541944576ff08 267 PIRSF PIRSF003092 1 267 3.2E-88 T 11-10-2018 IPR025501 ATP binding protein MinD TO73_1441 ceb12d3b92113904e1c541944576ff08 267 SUPERFAMILY SSF52540 3 248 2.03E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1691 fc6c20a377425ffb781cdfeea366b4f2 90 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 4 84 2.0E-39 T 11-10-2018 IPR007347 Sporulation stage V, protein S TO73_1691 fc6c20a377425ffb781cdfeea366b4f2 90 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 83 1.3E-37 T 11-10-2018 IPR007347 Sporulation stage V, protein S TO73_1691 fc6c20a377425ffb781cdfeea366b4f2 90 Gene3D G3DSA:3.30.110.20 1 90 1.0E-39 T 11-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TO73_1745 a28fc65f8cd7229cb5f7e6a4941c36c2 163 SUPERFAMILY SSF111384 28 162 4.05E-21 T 11-10-2018 TO73_1745 a28fc65f8cd7229cb5f7e6a4941c36c2 163 Pfam PF03938 Outer membrane protein (OmpH-like) 14 161 3.3E-21 T 11-10-2018 IPR005632 Chaperone protein Skp GO:0051082 TO73_1745 a28fc65f8cd7229cb5f7e6a4941c36c2 163 SMART SM00935 12 162 2.9E-24 T 11-10-2018 IPR005632 Chaperone protein Skp GO:0051082 TO73_1745 a28fc65f8cd7229cb5f7e6a4941c36c2 163 Gene3D G3DSA:3.30.910.20 19 162 6.5E-19 T 11-10-2018 IPR024930 Skp domain superfamily TO73_0285 a2f07e6c87469d7cca8a3ae1c1e67aa5 169 Gene3D G3DSA:1.20.1260.10 30 169 3.8E-32 T 11-10-2018 IPR012347 Ferritin-like TO73_0285 a2f07e6c87469d7cca8a3ae1c1e67aa5 169 Pfam PF03713 Domain of unknown function (DUF305) 32 167 3.9E-30 T 11-10-2018 IPR005183 Domain of unknown function DUF305 TO73_1267 f9e34c803a13a71593d12f6d11e74e24 337 Gene3D G3DSA:3.40.50.1980 74 204 9.2E-35 T 11-10-2018 TO73_1267 f9e34c803a13a71593d12f6d11e74e24 337 Pfam PF01497 Periplasmic binding protein 92 307 2.2E-31 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain TO73_1267 f9e34c803a13a71593d12f6d11e74e24 337 SUPERFAMILY SSF53807 70 336 7.06E-66 T 11-10-2018 TO73_1267 f9e34c803a13a71593d12f6d11e74e24 337 Gene3D G3DSA:3.40.50.1980 208 336 6.8E-31 T 11-10-2018 TO73_1208 7870c949aaa639cb7575257341ed9302 333 Pfam PF10123 Mu-like prophage I protein 32 331 3.8E-47 T 11-10-2018 IPR012106 Protease, Mu phage/prophage I type TO73_1066 6974842ad7858c52b3500f92ee6a4f91 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 58 70 7.3E-25 T 11-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TO73_1066 6974842ad7858c52b3500f92ee6a4f91 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 2 25 7.3E-25 T 11-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TO73_1066 6974842ad7858c52b3500f92ee6a4f91 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 128 144 7.3E-25 T 11-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TO73_1066 6974842ad7858c52b3500f92ee6a4f91 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 76 96 7.3E-25 T 11-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TO73_1066 6974842ad7858c52b3500f92ee6a4f91 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 155 167 7.3E-25 T 11-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TO73_1066 6974842ad7858c52b3500f92ee6a4f91 192 PIRSF PIRSF015592 1 192 2.9E-53 T 11-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TO73_1066 6974842ad7858c52b3500f92ee6a4f91 192 Pfam PF01470 Pyroglutamyl peptidase 2 191 3.0E-42 T 11-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 TO73_1066 6974842ad7858c52b3500f92ee6a4f91 192 Gene3D G3DSA:3.40.630.20 1 192 2.3E-66 T 11-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TO73_1066 6974842ad7858c52b3500f92ee6a4f91 192 SUPERFAMILY SSF53182 2 191 3.66E-53 T 11-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TO73_1086 60072920131fcbc9e1cf7d1ca7466889 491 SUPERFAMILY SSF109755 290 477 1.96E-12 T 11-10-2018 TO73_1086 60072920131fcbc9e1cf7d1ca7466889 491 Pfam PF01895 PhoU domain 305 386 2.1E-4 T 11-10-2018 IPR026022 PhoU domain TO73_1086 60072920131fcbc9e1cf7d1ca7466889 491 Pfam PF02690 Na+/Pi-cotransporter 9 138 5.9E-10 T 11-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 TO73_1766 045ae22b170b515a53ecbd0b99a51b52 845 Gene3D G3DSA:3.30.70.1230 10 185 8.0E-28 T 11-10-2018 IPR029787 Nucleotide cyclase TO73_1766 045ae22b170b515a53ecbd0b99a51b52 845 SUPERFAMILY SSF55073 11 177 2.51E-29 T 11-10-2018 IPR029787 Nucleotide cyclase TO73_1766 045ae22b170b515a53ecbd0b99a51b52 845 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 17 179 1.2E-5 T 11-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TO73_1766 045ae22b170b515a53ecbd0b99a51b52 845 SUPERFAMILY SSF48452 469 676 1.21E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2777 d603527445a92e22a93996d421af3847 245 SUPERFAMILY SSF53098 112 236 4.3E-7 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2777 d603527445a92e22a93996d421af3847 245 Gene3D G3DSA:3.30.420.10 110 240 2.5E-7 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_1850 af8ceb25aa7e6c4a030ab9936ba3b67b 443 SUPERFAMILY SSF56317 178 418 3.01E-37 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TO73_1850 af8ceb25aa7e6c4a030ab9936ba3b67b 443 Gene3D G3DSA:3.60.110.10 245 407 2.1E-16 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TO73_1850 af8ceb25aa7e6c4a030ab9936ba3b67b 443 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 1 424 17.765 T 11-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 TO73_1850 af8ceb25aa7e6c4a030ab9936ba3b67b 443 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 42 387 5.2E-63 T 11-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 TO73_1850 af8ceb25aa7e6c4a030ab9936ba3b67b 443 Pfam PF00795 Carbon-nitrogen hydrolase 251 401 1.1E-19 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TO73_0351 44c4322b4bb0add98119679cd6092487 696 Gene3D G3DSA:3.30.230.10 455 690 6.3E-86 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TO73_0351 44c4322b4bb0add98119679cd6092487 696 SUPERFAMILY SSF54211 477 670 7.59E-32 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TO73_0351 44c4322b4bb0add98119679cd6092487 696 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 562 667 5.5E-10 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TO73_0351 44c4322b4bb0add98119679cd6092487 696 Gene3D G3DSA:1.20.120.1680 88 228 4.2E-53 T 11-10-2018 TO73_0351 44c4322b4bb0add98119679cd6092487 696 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 619 637 8.8E-9 T 11-10-2018 TO73_0351 44c4322b4bb0add98119679cd6092487 696 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 45 64 8.8E-9 T 11-10-2018 TO73_0351 44c4322b4bb0add98119679cd6092487 696 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 589 608 8.8E-9 T 11-10-2018 TO73_0351 44c4322b4bb0add98119679cd6092487 696 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 559 578 8.8E-9 T 11-10-2018 TO73_0351 44c4322b4bb0add98119679cd6092487 696 SUPERFAMILY SSF52540 15 421 2.35E-6 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0351 44c4322b4bb0add98119679cd6092487 696 Pfam PF13654 AAA domain 17 152 8.3E-13 T 11-10-2018 TO73_0351 44c4322b4bb0add98119679cd6092487 696 Pfam PF13654 AAA domain 163 452 4.1E-37 T 11-10-2018 TO73_0351 44c4322b4bb0add98119679cd6092487 696 Gene3D G3DSA:1.10.8.60 377 453 7.7E-30 T 11-10-2018 TO73_0351 44c4322b4bb0add98119679cd6092487 696 Gene3D G3DSA:3.40.50.300 229 350 7.3E-10 T 11-10-2018 TO73_2042 78c01c5285af652343449cd662a6f7ea 344 SUPERFAMILY SSF51735 140 310 5.92E-32 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily TO73_2042 78c01c5285af652343449cd662a6f7ea 344 Pfam PF13823 Alcohol dehydrogenase GroES-associated 2 23 2.5E-8 T 11-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated TO73_2042 78c01c5285af652343449cd662a6f7ea 344 Gene3D G3DSA:3.40.50.720 156 290 6.2E-97 T 11-10-2018 TO73_2042 78c01c5285af652343449cd662a6f7ea 344 Gene3D G3DSA:3.90.180.10 14 332 6.2E-97 T 11-10-2018 TO73_2042 78c01c5285af652343449cd662a6f7ea 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 135 6.1E-25 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TO73_2042 78c01c5285af652343449cd662a6f7ea 344 SUPERFAMILY SSF50129 2 163 3.93E-43 T 11-10-2018 IPR011032 GroES-like superfamily TO73_2042 78c01c5285af652343449cd662a6f7ea 344 Pfam PF00107 Zinc-binding dehydrogenase 177 302 5.1E-19 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TO73_2042 78c01c5285af652343449cd662a6f7ea 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TO73_1832 f60c9d906bc11faf1cb283e6598453d7 86 Pfam PF07704 Rv0623-like transcription factor 1 84 3.1E-19 T 11-10-2018 IPR011660 Antitoxin VapB-like TO73_0279 1f9fb30b329987b921795021c1c17f60 236 SUPERFAMILY SSF53474 4 233 2.42E-44 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0279 1f9fb30b329987b921795021c1c17f60 236 Gene3D G3DSA:3.40.50.1820 2 235 8.4E-52 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0279 1f9fb30b329987b921795021c1c17f60 236 Pfam PF12697 Alpha/beta hydrolase family 4 224 5.2E-12 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_1072 7453384e2e65bc2264a4758fc4a87782 222 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 122 209 3.8E-24 T 11-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 TO73_1072 7453384e2e65bc2264a4758fc4a87782 222 Gene3D G3DSA:3.40.50.150 2 216 1.2E-43 T 11-10-2018 TO73_0183 6004f185eb147e854b093ac9bab5c2c1 106 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 7 24 1.8E-6 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TO73_0183 6004f185eb147e854b093ac9bab5c2c1 106 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 24 44 1.8E-6 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TO73_0183 6004f185eb147e854b093ac9bab5c2c1 106 Pfam PF02954 Bacterial regulatory protein, Fis family 7 41 3.1E-6 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TO73_0183 6004f185eb147e854b093ac9bab5c2c1 106 Gene3D G3DSA:1.10.10.60 1 44 5.1E-7 T 11-10-2018 TO73_1632 0acfa9054b2133c7fb22df12b6c8bd1a 291 Gene3D G3DSA:3.10.310.10 126 282 5.6E-39 T 11-10-2018 TO73_1632 0acfa9054b2133c7fb22df12b6c8bd1a 291 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 290 8.9E-48 T 11-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TO73_1632 0acfa9054b2133c7fb22df12b6c8bd1a 291 Pfam PF02567 Phenazine biosynthesis-like protein 3 289 2.7E-56 T 11-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TO73_1632 0acfa9054b2133c7fb22df12b6c8bd1a 291 SUPERFAMILY SSF54506 2 291 3.88E-55 T 11-10-2018 TO73_1632 0acfa9054b2133c7fb22df12b6c8bd1a 291 Gene3D G3DSA:3.10.310.10 1 125 2.1E-26 T 11-10-2018 TO73_1632 0acfa9054b2133c7fb22df12b6c8bd1a 291 PIRSF PIRSF016184 1 291 3.2E-64 T 11-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TO73_0601 359f3f597507ebeb770a23a12fef229f 442 Pfam PF02653 Branched-chain amino acid transport system / permease component 112 421 3.1E-48 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_1743 4a972d2221d51c995ec98929edc9f90e 129 Pfam PF02675 S-adenosylmethionine decarboxylase 7 114 2.4E-21 T 11-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TO73_1743 4a972d2221d51c995ec98929edc9f90e 129 SUPERFAMILY SSF56276 3 116 1.41E-24 T 11-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TO73_1743 4a972d2221d51c995ec98929edc9f90e 129 Gene3D G3DSA:3.60.90.10 2 123 7.3E-23 T 11-10-2018 TO73_0769 8552c576df956a8166a21c151a192bb8 422 Pfam PF07282 Putative transposase DNA-binding domain 299 368 3.7E-21 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_0769 8552c576df956a8166a21c151a192bb8 422 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 254 326 3.2E-11 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_0769 8552c576df956a8166a21c151a192bb8 422 Pfam PF12323 Helix-turn-helix domain 1 48 1.3E-13 T 11-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain TO73_0769 8552c576df956a8166a21c151a192bb8 422 Pfam PF01385 Probable transposase 172 286 5.4E-24 T 11-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TO73_0514 cb246dc031949575c88edac2db155b15 139 Gene3D G3DSA:2.60.40.2470 11 139 1.1E-46 T 11-10-2018 IPR038162 Ig-like SoxY domain superfamily TO73_0514 cb246dc031949575c88edac2db155b15 139 PIRSF PIRSF010312 1 139 3.7E-45 T 11-10-2018 IPR016568 Sulphur oxidation, SoxY TO73_0514 cb246dc031949575c88edac2db155b15 139 TIGRFAM TIGR04488 SoxY_true_GGCGG: thiosulfate oxidation carrier protein SoxY 4 139 2.2E-39 T 11-10-2018 IPR016568 Sulphur oxidation, SoxY TO73_0514 cb246dc031949575c88edac2db155b15 139 Pfam PF13501 Sulfur oxidation protein SoxY 41 138 2.1E-30 T 11-10-2018 IPR032711 Ig-like SoxY domain TO73_0964 401f4941e264b8d34161caf8bd8396ff 882 SUPERFAMILY SSF117074 698 754 1.83E-8 T 11-10-2018 TO73_0964 401f4941e264b8d34161caf8bd8396ff 882 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 456 494 1.1E-5 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0964 401f4941e264b8d34161caf8bd8396ff 882 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 566 615 2.6E-5 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0964 401f4941e264b8d34161caf8bd8396ff 882 Pfam PF01345 Domain of unknown function DUF11 190 297 2.3E-6 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0964 401f4941e264b8d34161caf8bd8396ff 882 Pfam PF01345 Domain of unknown function DUF11 564 663 3.9E-11 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0964 401f4941e264b8d34161caf8bd8396ff 882 Pfam PF01345 Domain of unknown function DUF11 447 536 1.5E-11 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0964 401f4941e264b8d34161caf8bd8396ff 882 Gene3D G3DSA:2.60.40.10 695 771 9.3E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_1335 43724b6370f6b50df6c525b9a8ee59f7 332 Gene3D G3DSA:3.40.50.300 32 273 7.1E-55 T 11-10-2018 TO73_1335 43724b6370f6b50df6c525b9a8ee59f7 332 SMART SM00382 53 240 5.8E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1335 43724b6370f6b50df6c525b9a8ee59f7 332 Pfam PF00005 ABC transporter 45 188 8.7E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_1335 43724b6370f6b50df6c525b9a8ee59f7 332 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1335 43724b6370f6b50df6c525b9a8ee59f7 332 SUPERFAMILY SSF52540 37 258 2.42E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1291 c009fe577c28e1792acc3509189e9623 283 SUPERFAMILY SSF52151 1 257 7.59E-46 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TO73_1291 c009fe577c28e1792acc3509189e9623 283 Pfam PF01734 Patatin-like phospholipase 3 172 1.6E-23 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 TO73_1291 c009fe577c28e1792acc3509189e9623 283 Gene3D G3DSA:3.40.1090.10 1 84 1.9E-15 T 11-10-2018 TO73_1291 c009fe577c28e1792acc3509189e9623 283 Gene3D G3DSA:3.40.1090.10 85 195 1.7E-14 T 11-10-2018 TO73_0097 99b7e984f5c2601daff8c3a7540d315b 54 TIGRFAM TIGR01206 lysW: lysine biosynthesis protein LysW 1 54 7.1E-34 T 11-10-2018 IPR005906 Lysine biosynthesis protein LysW TO73_0097 99b7e984f5c2601daff8c3a7540d315b 54 Gene3D G3DSA:2.20.28.160 1 54 9.3E-27 T 11-10-2018 TO73_0097 99b7e984f5c2601daff8c3a7540d315b 54 SUPERFAMILY SSF161187 1 35 3.79E-5 T 11-10-2018 TO73_0097 99b7e984f5c2601daff8c3a7540d315b 54 Pfam PF08271 TFIIB zinc-binding 4 40 4.7E-10 T 11-10-2018 IPR013137 Zinc finger, TFIIB-type TO73_1516 acc297fb330bf378a80051c5e6701a96 200 Gene3D G3DSA:3.40.50.300 2 186 4.4E-46 T 11-10-2018 TO73_1516 acc297fb330bf378a80051c5e6701a96 200 Pfam PF01712 Deoxynucleoside kinase 3 195 8.0E-40 T 11-10-2018 IPR031314 Deoxynucleoside kinase domain TO73_1516 acc297fb330bf378a80051c5e6701a96 200 PIRSF PIRSF000705 1 200 1.0E-51 T 11-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 TO73_1516 acc297fb330bf378a80051c5e6701a96 200 SUPERFAMILY SSF52540 3 181 2.01E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0528 2edcdbf4bf430411bce8fee37f17640a 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 1.9E-40 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0528 2edcdbf4bf430411bce8fee37f17640a 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 131 148 1.9E-40 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0528 2edcdbf4bf430411bce8fee37f17640a 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 81 107 1.9E-40 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0528 2edcdbf4bf430411bce8fee37f17640a 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 293 309 1.9E-40 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0528 2edcdbf4bf430411bce8fee37f17640a 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 273 293 1.9E-40 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0528 2edcdbf4bf430411bce8fee37f17640a 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 243 263 1.9E-40 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0528 2edcdbf4bf430411bce8fee37f17640a 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 209 235 1.9E-40 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0528 2edcdbf4bf430411bce8fee37f17640a 643 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 313 626 2.3E-45 T 11-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal TO73_0528 2edcdbf4bf430411bce8fee37f17640a 643 Pfam PF01578 Cytochrome C assembly protein 90 294 1.8E-31 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TO73_1166 41bd2e5654a0798d178a730906567eec 347 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 73 274 2.4E-18 T 11-10-2018 IPR000477 Reverse transcriptase domain TO73_1166 41bd2e5654a0798d178a730906567eec 347 SUPERFAMILY SSF56672 38 323 1.95E-28 T 11-10-2018 TO73_1183 df4e785475eb9555df88218c51c6b3d1 389 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 61 168 3.5E-16 T 11-10-2018 IPR006528 Phage head morphogenesis domain TO73_1183 df4e785475eb9555df88218c51c6b3d1 389 Pfam PF04233 Phage Mu protein F like protein 54 167 9.0E-22 T 11-10-2018 IPR006528 Phage head morphogenesis domain TO73_0288 0dc1c968ac1ce0d94ee6f3a51ff57c5e 128 Gene3D G3DSA:2.70.70.10 1 107 5.5E-22 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_0288 0dc1c968ac1ce0d94ee6f3a51ff57c5e 128 SUPERFAMILY SSF51261 24 83 7.32E-20 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_0288 0dc1c968ac1ce0d94ee6f3a51ff57c5e 128 Pfam PF01551 Peptidase family M23 26 83 4.1E-16 T 11-10-2018 IPR016047 Peptidase M23 TO73_0873 f05535f0e5f43e264934a37be84e9e27 238 SUPERFAMILY SSF53790 1 226 4.97E-58 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TO73_0873 f05535f0e5f43e264934a37be84e9e27 238 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 79 112 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TO73_0873 f05535f0e5f43e264934a37be84e9e27 238 Gene3D G3DSA:3.30.950.10 115 232 3.5E-33 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TO73_0873 f05535f0e5f43e264934a37be84e9e27 238 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 224 6.0E-71 T 11-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TO73_0873 f05535f0e5f43e264934a37be84e9e27 238 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 204 3.2E-41 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TO73_0873 f05535f0e5f43e264934a37be84e9e27 238 Gene3D G3DSA:3.40.1010.10 1 114 1.3E-43 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TO73_0873 f05535f0e5f43e264934a37be84e9e27 238 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TO73_0519 ade64f9f82184a8416c06db0eb324001 283 SUPERFAMILY SSF103247 20 137 2.62E-12 T 11-10-2018 IPR035923 TT1751-like domain superfamily TO73_0519 ade64f9f82184a8416c06db0eb324001 283 SUPERFAMILY SSF103247 168 274 9.94E-11 T 11-10-2018 IPR035923 TT1751-like domain superfamily TO73_1373 0db9f42ab3131b7a7965dfeb0d02d740 391 Gene3D G3DSA:3.30.830.10 1 195 8.3E-32 T 11-10-2018 TO73_1373 0db9f42ab3131b7a7965dfeb0d02d740 391 Pfam PF05193 Peptidase M16 inactive domain 155 319 9.3E-24 T 11-10-2018 IPR007863 Peptidase M16, C-terminal TO73_1373 0db9f42ab3131b7a7965dfeb0d02d740 391 SUPERFAMILY SSF63411 201 380 6.0E-38 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TO73_1373 0db9f42ab3131b7a7965dfeb0d02d740 391 SUPERFAMILY SSF63411 1 190 6.81E-35 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TO73_1373 0db9f42ab3131b7a7965dfeb0d02d740 391 Pfam PF00675 Insulinase (Peptidase family M16) 10 129 4.6E-9 T 11-10-2018 IPR011765 Peptidase M16, N-terminal TO73_1373 0db9f42ab3131b7a7965dfeb0d02d740 391 Gene3D G3DSA:3.30.830.10 206 391 6.1E-45 T 11-10-2018 TO73_0860 5af4e189d9fad9259b8d739dba19e784 109 Pfam PF01909 Nucleotidyltransferase domain 20 79 2.0E-7 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TO73_0860 5af4e189d9fad9259b8d739dba19e784 109 SUPERFAMILY SSF81301 4 105 5.14E-22 T 11-10-2018 TO73_0860 5af4e189d9fad9259b8d739dba19e784 109 Gene3D G3DSA:3.30.460.10 3 95 3.1E-15 T 11-10-2018 TO73_2192 4cb85fd0c5d0c30df02ee3195a7822e6 69 Gene3D G3DSA:3.20.20.140 10 68 3.0E-7 T 11-10-2018 TO73_2192 4cb85fd0c5d0c30df02ee3195a7822e6 69 SUPERFAMILY SSF51338 17 68 3.74E-6 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TO73_1239 c478e4de75bffe4d95e5c3b0500b6a7e 277 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 153 164 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TO73_1239 c478e4de75bffe4d95e5c3b0500b6a7e 277 SUPERFAMILY SSF54862 66 276 3.77E-63 T 11-10-2018 TO73_1239 c478e4de75bffe4d95e5c3b0500b6a7e 277 Pfam PF13247 4Fe-4S dicluster domain 113 172 3.0E-11 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_1239 c478e4de75bffe4d95e5c3b0500b6a7e 277 Pfam PF13247 4Fe-4S dicluster domain 210 243 1.0E-8 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TO73_1239 c478e4de75bffe4d95e5c3b0500b6a7e 277 Gene3D G3DSA:3.30.70.20 51 101 6.0E-10 T 11-10-2018 TO73_1239 c478e4de75bffe4d95e5c3b0500b6a7e 277 Gene3D G3DSA:3.30.70.20 102 277 2.4E-51 T 11-10-2018 TO73_0620 853625efca499de369df64efd21928bb 185 SUPERFAMILY SSF52980 4 180 5.9E-21 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_0620 853625efca499de369df64efd21928bb 185 Gene3D G3DSA:3.90.1570.10 2 181 6.6E-18 T 11-10-2018 TO73_0620 853625efca499de369df64efd21928bb 185 Pfam PF05685 Putative restriction endonuclease 10 178 4.8E-34 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1989 f852b427bcfcf6f7b3e66cd697a8062f 199 Gene3D G3DSA:2.40.100.10 44 198 3.8E-50 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily TO73_1989 f852b427bcfcf6f7b3e66cd697a8062f 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 131 146 2.1E-17 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TO73_1989 f852b427bcfcf6f7b3e66cd697a8062f 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 159 174 2.1E-17 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TO73_1989 f852b427bcfcf6f7b3e66cd697a8062f 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 146 158 2.1E-17 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TO73_1989 f852b427bcfcf6f7b3e66cd697a8062f 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 64 79 2.1E-17 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TO73_1989 f852b427bcfcf6f7b3e66cd697a8062f 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 90 102 2.1E-17 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TO73_1989 f852b427bcfcf6f7b3e66cd697a8062f 199 SUPERFAMILY SSF50891 40 181 1.9E-48 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily TO73_1989 f852b427bcfcf6f7b3e66cd697a8062f 199 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 51 180 9.7E-41 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TO73_1262 9527e9cdc2f282a2971643016a395d61 293 SUPERFAMILY SSF117396 3 291 5.75E-69 T 11-10-2018 IPR036520 UPF0759 superfamily TO73_1262 9527e9cdc2f282a2971643016a395d61 293 Gene3D G3DSA:3.20.20.410 1 293 8.6E-73 T 11-10-2018 IPR036520 UPF0759 superfamily TO73_1262 9527e9cdc2f282a2971643016a395d61 293 Pfam PF01904 Protein of unknown function DUF72 22 288 2.4E-57 T 11-10-2018 IPR002763 Protein of unknown function DUF72 TO73_0063 05bc29da005b3822c83822fa9687e689 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 123 20.132 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TO73_0063 05bc29da005b3822c83822fa9687e689 127 TIGRFAM TIGR00494 crcB: protein CrcB 7 120 2.6E-28 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TO73_0063 05bc29da005b3822c83822fa9687e689 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 118 5.5E-24 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TO73_1226 0d7abe4ff7cbd5c2c2977e8ba7851d28 283 ProSitePatterns PS01347 MraY family signature 1. 39 51 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_1226 0d7abe4ff7cbd5c2c2977e8ba7851d28 283 Pfam PF00953 Glycosyl transferase family 4 68 208 1.6E-26 T 11-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TO73_1226 0d7abe4ff7cbd5c2c2977e8ba7851d28 283 ProSitePatterns PS01348 MraY family signature 2. 139 150 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_1226 0d7abe4ff7cbd5c2c2977e8ba7851d28 283 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 39 51 6.0E-5 T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_1929 30dc24001bab77fbc6a1ac92fdbdf6da 268 PIRSF PIRSF036894 8 39 5.1 T 11-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TO73_1929 30dc24001bab77fbc6a1ac92fdbdf6da 268 PIRSF PIRSF036894 37 231 1.7E-54 T 11-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TO73_1929 30dc24001bab77fbc6a1ac92fdbdf6da 268 SUPERFAMILY SSF51182 10 244 2.51E-53 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily TO73_1929 30dc24001bab77fbc6a1ac92fdbdf6da 268 Gene3D G3DSA:2.60.120.10 32 173 2.5E-45 T 11-10-2018 IPR014710 RmlC-like jelly roll fold TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 1.2E-164 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 SMART SM00382 57 228 1.8E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 SUPERFAMILY SSF52540 4 268 3.67E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 Pfam PF00154 recA bacterial DNA recombination protein 7 268 8.7E-138 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 ProSitePatterns PS00321 recA signature. 213 221 - T 11-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 SUPERFAMILY SSF54752 273 325 1.06E-16 T 11-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 Gene3D G3DSA:3.40.50.300 26 268 3.7E-82 T 11-10-2018 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 PRINTS PR00142 RecA protein signature 165 194 6.2E-77 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 PRINTS PR00142 RecA protein signature 210 238 6.2E-77 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 PRINTS PR00142 RecA protein signature 298 315 6.2E-77 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 PRINTS PR00142 RecA protein signature 127 156 6.2E-77 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 PRINTS PR00142 RecA protein signature 93 122 6.2E-77 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 PRINTS PR00142 RecA protein signature 244 273 6.2E-77 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 Hamap MF_00268 Protein RecA [recA]. 5 330 51.252 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TO73_0318 fb1a6c5bdedeafdcd57badd95e6c0551 340 Gene3D G3DSA:3.30.250.10 269 327 2.1E-22 T 11-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TO73_2171 caa54ce9d1700069d5f47e07e22eedba 181 Gene3D G3DSA:3.40.50.1010 1 163 8.1E-40 T 11-10-2018 TO73_2171 caa54ce9d1700069d5f47e07e22eedba 181 Pfam PF01936 NYN domain 3 160 3.7E-31 T 11-10-2018 IPR021139 NYN domain, limkain-b1-type TO73_2138 265eae811c3ea5eef3b74a5f9579c6e2 349 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 334 2.6E-67 T 11-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 TO73_2138 265eae811c3ea5eef3b74a5f9579c6e2 349 Gene3D G3DSA:3.20.20.70 1 349 9.0E-129 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_2138 265eae811c3ea5eef3b74a5f9579c6e2 349 SUPERFAMILY SSF51395 1 342 8.25E-116 T 11-10-2018 TO73_1449 51bb29c4a4b6472b2b1102d0a28e9ebd 85 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 8 85 1.1E-33 T 11-10-2018 IPR019886 Sodium symporter small subunit, predicted TO73_1449 51bb29c4a4b6472b2b1102d0a28e9ebd 85 Pfam PF13937 Domain of unknown function (DUF4212) 8 83 1.4E-33 T 11-10-2018 IPR019886 Sodium symporter small subunit, predicted TO73_2876 240468145e46e72348283314875eeb9a 918 SMART SM00490 491 575 2.8E-17 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_2876 240468145e46e72348283314875eeb9a 918 Pfam PF00271 Helicase conserved C-terminal domain 465 575 3.0E-15 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_2876 240468145e46e72348283314875eeb9a 918 SUPERFAMILY SSF52540 153 586 8.65E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2876 240468145e46e72348283314875eeb9a 918 Gene3D G3DSA:3.40.50.10810 103 362 5.1E-52 T 11-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily TO73_2876 240468145e46e72348283314875eeb9a 918 SMART SM00487 101 301 3.2E-18 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_2876 240468145e46e72348283314875eeb9a 918 Gene3D G3DSA:3.40.50.300 441 607 2.5E-34 T 11-10-2018 TO73_2876 240468145e46e72348283314875eeb9a 918 Pfam PF00176 SNF2 family N-terminal domain 125 291 2.3E-9 T 11-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 TO73_2298 b2a454a1dd63b366979cb1c839066dbb 402 SUPERFAMILY SSF89796 1 391 1.27E-145 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily TO73_2298 b2a454a1dd63b366979cb1c839066dbb 402 Gene3D G3DSA:3.30.1540.10 230 319 3.6E-140 T 11-10-2018 TO73_2298 b2a454a1dd63b366979cb1c839066dbb 402 Pfam PF02515 CoA-transferase family III 4 369 1.9E-134 T 11-10-2018 IPR003673 CoA-transferase family III GO:0003824 TO73_2298 b2a454a1dd63b366979cb1c839066dbb 402 Gene3D G3DSA:3.40.50.10540 3 386 3.6E-140 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily TO73_1621 65f73dfa059a1b07e90f0cde66d23740 265 Pfam PF01497 Periplasmic binding protein 20 209 2.1E-21 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain TO73_1621 65f73dfa059a1b07e90f0cde66d23740 265 SUPERFAMILY SSF53807 5 252 5.49E-39 T 11-10-2018 TO73_1621 65f73dfa059a1b07e90f0cde66d23740 265 Gene3D G3DSA:3.40.50.1980 13 135 2.9E-26 T 11-10-2018 TO73_1621 65f73dfa059a1b07e90f0cde66d23740 265 Gene3D G3DSA:3.40.50.1980 138 258 6.3E-10 T 11-10-2018 TO73_1402 dc940c61095d877cbb819e91c39415fb 211 Pfam PF02698 DUF218 domain 24 156 1.7E-27 T 11-10-2018 IPR003848 Domain of unknown function DUF218 TO73_2175 9366f3dc26283842b751fd369d828107 85 Gene3D G3DSA:3.40.50.620 32 81 4.4E-8 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_2175 9366f3dc26283842b751fd369d828107 85 PRINTS PR01438 Universal stress protein signature 58 80 2.4E-5 T 11-10-2018 IPR006015 Universal stress protein A TO73_2175 9366f3dc26283842b751fd369d828107 85 PRINTS PR01438 Universal stress protein signature 41 53 2.4E-5 T 11-10-2018 IPR006015 Universal stress protein A TO73_2175 9366f3dc26283842b751fd369d828107 85 Pfam PF00582 Universal stress protein family 33 80 4.2E-8 T 11-10-2018 IPR006016 UspA TO73_2175 9366f3dc26283842b751fd369d828107 85 SUPERFAMILY SSF52402 25 80 7.03E-9 T 11-10-2018 TO73_2084 94725dc8e3474aa24f1cbce2f461baac 515 SUPERFAMILY SSF161098 11 247 1.87E-40 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2084 94725dc8e3474aa24f1cbce2f461baac 515 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 341 508 7.0E-16 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_2084 94725dc8e3474aa24f1cbce2f461baac 515 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 240 1.3E-10 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_2084 94725dc8e3474aa24f1cbce2f461baac 515 Gene3D G3DSA:1.10.3720.10 273 514 2.2E-36 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2084 94725dc8e3474aa24f1cbce2f461baac 515 Gene3D G3DSA:1.10.3720.10 11 253 1.0E-49 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2084 94725dc8e3474aa24f1cbce2f461baac 515 SUPERFAMILY SSF161098 278 511 1.24E-36 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1986 fc01162fce74309fc7b0ea5652a5050d 142 Pfam PF00583 Acetyltransferase (GNAT) family 21 129 1.8E-12 T 11-10-2018 IPR000182 GNAT domain TO73_1986 fc01162fce74309fc7b0ea5652a5050d 142 PIRSF PIRSF000452 1 142 2.7E-39 T 11-10-2018 IPR024170 Aminoglycoside N6-acetyltransferase TO73_1986 fc01162fce74309fc7b0ea5652a5050d 142 SUPERFAMILY SSF55729 2 139 3.71E-27 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase TO73_1986 fc01162fce74309fc7b0ea5652a5050d 142 Gene3D G3DSA:3.40.630.30 1 142 6.2E-33 T 11-10-2018 TO73_2808 d28c0a06e0401fd84ef1c170c3a57d5d 213 Pfam PF01609 Transposase DDE domain 6 172 2.2E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_2808 d28c0a06e0401fd84ef1c170c3a57d5d 213 SUPERFAMILY SSF53098 17 179 6.07E-11 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_1717 7d8dd3409be74edfa1bb44a7af92bdc0 328 Gene3D G3DSA:3.60.70.12 10 326 8.2E-106 T 11-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TO73_1717 7d8dd3409be74edfa1bb44a7af92bdc0 328 Pfam PF03576 Peptidase family S58 14 315 3.7E-59 T 11-10-2018 IPR005321 Peptidase S58, DmpA TO73_1717 7d8dd3409be74edfa1bb44a7af92bdc0 328 SUPERFAMILY SSF56266 14 323 1.99E-68 T 11-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TO73_2190 5b24f2d7fd70b88afc7420951607a02b 164 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 143 3.2E-34 T 11-10-2018 IPR001453 MoaB/Mog domain TO73_2190 5b24f2d7fd70b88afc7420951607a02b 164 Gene3D G3DSA:3.40.980.10 1 164 1.2E-58 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily TO73_2190 5b24f2d7fd70b88afc7420951607a02b 164 SMART SM00852 5 149 1.9E-30 T 11-10-2018 IPR001453 MoaB/Mog domain TO73_2190 5b24f2d7fd70b88afc7420951607a02b 164 Pfam PF00994 Probable molybdopterin binding domain 5 148 5.6E-34 T 11-10-2018 IPR001453 MoaB/Mog domain TO73_2190 5b24f2d7fd70b88afc7420951607a02b 164 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 65 78 - T 11-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TO73_2190 5b24f2d7fd70b88afc7420951607a02b 164 SUPERFAMILY SSF53218 2 153 2.62E-47 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily TO73_2620 d67f6c4d3c8080ba7246b4a18d16cb41 76 SUPERFAMILY SSF47598 20 59 5.11E-5 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TO73_2620 d67f6c4d3c8080ba7246b4a18d16cb41 76 Pfam PF01402 Ribbon-helix-helix protein, copG family 22 59 7.7E-8 T 11-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TO73_0037 2383197b4de962c8a31272672d1ac23c 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 272 1.4E-14 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0037 2383197b4de962c8a31272672d1ac23c 280 Gene3D G3DSA:1.10.3720.10 6 271 2.4E-63 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0037 2383197b4de962c8a31272672d1ac23c 280 SUPERFAMILY SSF161098 9 280 2.88E-71 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0999 a05db28977fa04defad285ef5c20bf46 390 SUPERFAMILY SSF53822 21 386 1.77E-78 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_0999 a05db28977fa04defad285ef5c20bf46 390 Gene3D G3DSA:3.40.50.2300 23 368 3.6E-110 T 11-10-2018 TO73_0999 a05db28977fa04defad285ef5c20bf46 390 Gene3D G3DSA:3.40.50.2300 145 382 3.6E-110 T 11-10-2018 TO73_0999 a05db28977fa04defad285ef5c20bf46 390 Pfam PF13458 Periplasmic binding protein 21 381 7.3E-54 T 11-10-2018 IPR028081 Leucine-binding protein domain TO73_0999 a05db28977fa04defad285ef5c20bf46 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 250 268 2.7E-5 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TO73_0999 a05db28977fa04defad285ef5c20bf46 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 21 37 2.7E-5 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TO73_0999 a05db28977fa04defad285ef5c20bf46 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 62 80 2.7E-5 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TO73_0999 a05db28977fa04defad285ef5c20bf46 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 83 93 2.7E-5 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TO73_0522 9d99e455203a733e9cd4b60052babd5f 182 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 54 137 1.3E-10 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TO73_0522 9d99e455203a733e9cd4b60052babd5f 182 Gene3D G3DSA:1.10.760.10 29 165 4.4E-45 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0522 9d99e455203a733e9cd4b60052babd5f 182 SUPERFAMILY SSF46626 6 143 1.78E-19 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_1128 85fd6fded489187eebf30b8093f60f3b 317 Pfam PF02371 Transposase IS116/IS110/IS902 family 192 276 6.5E-21 T 11-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 TO73_1128 85fd6fded489187eebf30b8093f60f3b 317 Pfam PF01548 Transposase 4 150 1.5E-30 T 11-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 TO73_1549 2a13fa57ae160d3e97f24ce26c2299ba 246 Gene3D G3DSA:3.40.50.300 3 236 3.9E-60 T 11-10-2018 TO73_1549 2a13fa57ae160d3e97f24ce26c2299ba 246 SMART SM00382 28 216 1.0E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1549 2a13fa57ae160d3e97f24ce26c2299ba 246 SUPERFAMILY SSF52540 3 223 4.7E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1549 2a13fa57ae160d3e97f24ce26c2299ba 246 Pfam PF00005 ABC transporter 19 162 1.5E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0456 b35ca0b866c703dbb9a3c651a0fa978b 250 Pfam PF01578 Cytochrome C assembly protein 106 241 2.2E-12 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TO73_2832 9d96b22c65de4a3043036860fd0a75cd 287 SUPERFAMILY SSF53807 2 273 3.18E-23 T 11-10-2018 TO73_2832 9d96b22c65de4a3043036860fd0a75cd 287 Gene3D G3DSA:3.40.50.1980 154 274 1.1E-7 T 11-10-2018 TO73_2832 9d96b22c65de4a3043036860fd0a75cd 287 Gene3D G3DSA:3.40.50.1980 1 153 7.3E-15 T 11-10-2018 TO73_0322 bfd25ea3de27d03be89cc2f628699eee 210 SUPERFAMILY SSF55174 35 204 3.73E-7 T 11-10-2018 TO73_2250 7e921971df0196c0695ff35e9931cd9f 259 Gene3D G3DSA:1.20.58.1460 167 248 1.4E-5 T 11-10-2018 TO73_2250 7e921971df0196c0695ff35e9931cd9f 259 PIRSF PIRSF020623 1 259 2.6E-67 T 11-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 TO73_2250 7e921971df0196c0695ff35e9931cd9f 259 Gene3D G3DSA:1.10.10.10 1 82 2.0E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2250 7e921971df0196c0695ff35e9931cd9f 259 Pfam PF07848 PaaX-like protein 2 70 4.6E-22 T 11-10-2018 IPR012906 PaaX-like, N-terminal TO73_2250 7e921971df0196c0695ff35e9931cd9f 259 Pfam PF08223 PaaX-like protein C-terminal domain 177 245 4.7E-16 T 11-10-2018 IPR013225 PaaX-like, C-terminal TO73_1906 5e57ec53368721e939b71c14fe76f3f1 183 SUPERFAMILY SSF52980 4 150 6.43E-19 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1906 5e57ec53368721e939b71c14fe76f3f1 183 Gene3D G3DSA:3.90.1570.10 2 167 7.0E-14 T 11-10-2018 TO73_1906 5e57ec53368721e939b71c14fe76f3f1 183 Pfam PF05685 Putative restriction endonuclease 8 164 1.3E-26 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1729 1bb166933ebaac7d811bdd06a2cae101 72 SUPERFAMILY SSF46689 3 70 1.08E-23 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TO73_1729 1bb166933ebaac7d811bdd06a2cae101 72 Gene3D G3DSA:1.10.10.10 6 72 1.3E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1729 1bb166933ebaac7d811bdd06a2cae101 72 Pfam PF04255 Protein of unknown function (DUF433) 7 61 2.6E-25 T 11-10-2018 IPR007367 Protein of unknown function DUF433 TO73_1281 cfd050a5643cbc9c441d4cc0ff57a49a 198 SMART SM00418 3 92 0.0013 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_1281 cfd050a5643cbc9c441d4cc0ff57a49a 198 Pfam PF12802 MarR family 11 53 1.3E-9 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TO73_1281 cfd050a5643cbc9c441d4cc0ff57a49a 198 SMART SM00419 14 68 1.6E-5 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TO73_1281 cfd050a5643cbc9c441d4cc0ff57a49a 198 Gene3D G3DSA:1.10.10.10 1 77 1.1E-15 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1281 cfd050a5643cbc9c441d4cc0ff57a49a 198 SUPERFAMILY SSF46785 4 180 6.12E-25 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_2057 09ef84f33afd144951e8820ba121bb8d 280 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 272 8.6E-56 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TO73_2057 09ef84f33afd144951e8820ba121bb8d 280 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 2 271 6.6E-41 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TO73_2057 09ef84f33afd144951e8820ba121bb8d 280 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 279 14.044 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TO73_2280 62fe6f9dde84f4c89f32cf2493ac7697 122 SUPERFAMILY SSF54593 5 116 3.7E-6 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_1440 bd9aa17767bb77f1b186b4acea620476 73 SUPERFAMILY SSF55229 23 72 1.44E-9 T 11-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 TO73_1440 bd9aa17767bb77f1b186b4acea620476 73 Gene3D G3DSA:3.30.1070.10 11 73 2.0E-13 T 11-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 TO73_1440 bd9aa17767bb77f1b186b4acea620476 73 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 5 73 4.1E-22 T 11-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 TO73_1440 bd9aa17767bb77f1b186b4acea620476 73 Pfam PF03776 Septum formation topological specificity factor MinE 7 73 4.2E-21 T 11-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 TO73_1055 7a41383ebb3b8957dd5ad8fdf8ffbfee 282 Gene3D G3DSA:3.40.190.10 65 170 2.8E-54 T 11-10-2018 TO73_1055 7a41383ebb3b8957dd5ad8fdf8ffbfee 282 SUPERFAMILY SSF53850 1 236 5.44E-31 T 11-10-2018 TO73_1055 7a41383ebb3b8957dd5ad8fdf8ffbfee 282 Gene3D G3DSA:3.40.190.10 1 253 2.8E-54 T 11-10-2018 TO73_1055 7a41383ebb3b8957dd5ad8fdf8ffbfee 282 Pfam PF09084 NMT1/THI5 like 1 162 1.1E-23 T 11-10-2018 IPR015168 SsuA/THI5-like TO73_2404 9c59ba39cc08d63ab85e2b93fc24f6c6 71 SUPERFAMILY SSF81593 2 71 1.02E-18 T 11-10-2018 TO73_2404 9c59ba39cc08d63ab85e2b93fc24f6c6 71 Pfam PF05168 HEPN domain 3 71 2.7E-10 T 11-10-2018 IPR007842 HEPN domain TO73_2404 9c59ba39cc08d63ab85e2b93fc24f6c6 71 Gene3D G3DSA:1.20.120.330 1 71 2.1E-14 T 11-10-2018 TO73_0361 cd16da276033187b2899b1aeee9160d6 330 SUPERFAMILY SSF48576 12 329 7.2E-66 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily TO73_0361 cd16da276033187b2899b1aeee9160d6 330 Gene3D G3DSA:1.10.600.10 1 330 8.9E-114 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily TO73_0361 cd16da276033187b2899b1aeee9160d6 330 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 90 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site TO73_0361 cd16da276033187b2899b1aeee9160d6 330 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 204 216 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site TO73_0361 cd16da276033187b2899b1aeee9160d6 330 Pfam PF00348 Polyprenyl synthetase 26 276 5.0E-52 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TO73_0839 f22062b4e36a88b606dcf3fba507caa5 277 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 257 3.2E-29 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_0815 f4cfbf3129d9ca8579d00d58ad177031 359 Gene3D G3DSA:3.40.1360.10 143 252 5.0E-9 T 11-10-2018 TO73_0815 f4cfbf3129d9ca8579d00d58ad177031 359 SUPERFAMILY SSF56731 186 254 1.83E-6 T 11-10-2018 TO73_0815 f4cfbf3129d9ca8579d00d58ad177031 359 Pfam PF13362 Toprim domain 153 243 1.2E-16 T 11-10-2018 IPR006171 TOPRIM domain TO73_2276 405bdf7b9f03e5dd1793462521a606d7 350 Pfam PF04055 Radical SAM superfamily 85 245 1.1E-20 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TO73_2276 405bdf7b9f03e5dd1793462521a606d7 350 SMART SM00729 78 287 0.0087 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TO73_2276 405bdf7b9f03e5dd1793462521a606d7 350 Gene3D G3DSA:3.20.20.70 71 298 6.0E-35 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TO73_2276 405bdf7b9f03e5dd1793462521a606d7 350 SUPERFAMILY SSF102114 54 326 1.96E-34 T 11-10-2018 TO73_2276 405bdf7b9f03e5dd1793462521a606d7 350 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 15 348 2.0E-110 T 11-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme TO73_2276 405bdf7b9f03e5dd1793462521a606d7 350 PIRSF PIRSF004869 2 325 9.2E-105 T 11-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TO73_2080 3d67313cf6b29c23758e63c6322db286 243 Pfam PF02591 C4-type zinc ribbon domain 207 238 1.6E-8 T 11-10-2018 IPR003743 C4-type zinc ribbon domain TO73_2845 72b59f1f7f9205d8bbc153bf042b6430 99 SUPERFAMILY SSF88723 6 68 2.0E-5 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_0919 72b59f1f7f9205d8bbc153bf042b6430 99 SUPERFAMILY SSF88723 6 68 2.0E-5 T 11-10-2018 IPR029060 PIN-like domain superfamily TO73_1988 19266290ee6a16741f0dd4c1c5eea203 180 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 8 180 3.7E-48 T 11-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TO73_1988 19266290ee6a16741f0dd4c1c5eea203 180 Hamap MF_00146 dCTP deaminase [dcd]. 3 180 26.209 T 11-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TO73_1988 19266290ee6a16741f0dd4c1c5eea203 180 SUPERFAMILY SSF51283 2 179 9.03E-50 T 11-10-2018 IPR036157 dUTPase-like superfamily TO73_1988 19266290ee6a16741f0dd4c1c5eea203 180 Pfam PF00692 dUTPase 72 176 1.9E-7 T 11-10-2018 IPR029054 dUTPase-like TO73_1988 19266290ee6a16741f0dd4c1c5eea203 180 Gene3D G3DSA:2.70.40.10 1 153 3.0E-49 T 11-10-2018 IPR036157 dUTPase-like superfamily TO73_0840 06bd11e1e2c3e2dec3240b1336818ffe 379 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 22 285 9.9E-43 T 11-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TO73_0840 06bd11e1e2c3e2dec3240b1336818ffe 379 Gene3D G3DSA:3.40.50.2300 124 365 6.1E-106 T 11-10-2018 TO73_0840 06bd11e1e2c3e2dec3240b1336818ffe 379 SUPERFAMILY SSF53822 66 211 1.35E-6 T 11-10-2018 IPR028082 Periplasmic binding protein-like I TO73_0840 06bd11e1e2c3e2dec3240b1336818ffe 379 Gene3D G3DSA:3.40.50.2300 24 282 6.1E-106 T 11-10-2018 TO73_0483 cf77055da56ae22e71af7bb0863ff99f 178 Gene3D G3DSA:2.60.120.1140 32 160 2.7E-38 T 11-10-2018 IPR038695 Saro_0823-like superfamily TO73_0483 cf77055da56ae22e71af7bb0863ff99f 178 Pfam PF02643 Uncharacterized ACR, COG1430 56 159 1.6E-31 T 11-10-2018 IPR003795 Protein of unknown function DUF192 TO73_0182 44a15bf819b4ee3d75a1a2a6f751032f 118 Pfam PF05866 Endodeoxyribonuclease RusA 9 105 9.4E-17 T 11-10-2018 IPR008822 Holliday junction resolvase RusA-like GO:0000287|GO:0006281|GO:0006310 TO73_0182 44a15bf819b4ee3d75a1a2a6f751032f 118 Gene3D G3DSA:3.30.1330.70 1 117 4.5E-36 T 11-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 TO73_0182 44a15bf819b4ee3d75a1a2a6f751032f 118 SUPERFAMILY SSF103084 4 115 1.96E-27 T 11-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 TO73_0182 44a15bf819b4ee3d75a1a2a6f751032f 118 PIRSF PIRSF001007 1 118 9.0E-34 T 11-10-2018 IPR016281 Crossover junction endodeoxyribonuclease, RusA GO:0008821 TO73_0476 185ec1c994de0c5998ec6f7a10244931 173 Pfam PF00156 Phosphoribosyl transferase domain 35 159 6.4E-15 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TO73_0476 185ec1c994de0c5998ec6f7a10244931 173 Gene3D G3DSA:3.40.50.2020 1 170 6.6E-49 T 11-10-2018 TO73_0476 185ec1c994de0c5998ec6f7a10244931 173 SUPERFAMILY SSF53271 8 158 1.13E-26 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_0278 e1788c867ea9d80b5faba25db5e10d7a 178 Gene3D G3DSA:3.90.1570.10 5 178 3.7E-17 T 11-10-2018 TO73_0278 e1788c867ea9d80b5faba25db5e10d7a 178 Pfam PF05685 Putative restriction endonuclease 17 155 8.6E-28 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_0278 e1788c867ea9d80b5faba25db5e10d7a 178 SUPERFAMILY SSF52980 11 173 1.29E-25 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_2275 0d01339e5f2177a382ea9fccf9debc7f 469 Pfam PF04434 SWIM zinc finger 57 88 5.3E-7 T 11-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 TO73_2353 b33d90ee1e8c4910bbe29a6e04b85d5f 232 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 6 164 3.7E-11 T 11-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain TO73_1863 9ecd2b7bd28019e2edc603f426d3f6b6 450 SUPERFAMILY SSF161098 246 432 2.94E-19 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1863 9ecd2b7bd28019e2edc603f426d3f6b6 450 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 7 55 1.1E-11 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TO73_1863 9ecd2b7bd28019e2edc603f426d3f6b6 450 Gene3D G3DSA:1.10.3720.10 239 445 4.0E-13 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1863 9ecd2b7bd28019e2edc603f426d3f6b6 450 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 271 449 4.2E-25 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1778 6f20bdd419a88be121444a2a598a84b7 127 Pfam PF01597 Glycine cleavage H-protein 8 126 2.5E-46 T 11-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate TO73_1778 6f20bdd419a88be121444a2a598a84b7 127 SUPERFAMILY SSF51230 3 126 2.75E-49 T 11-10-2018 IPR011053 Single hybrid motif TO73_1778 6f20bdd419a88be121444a2a598a84b7 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TO73_1778 6f20bdd419a88be121444a2a598a84b7 127 Gene3D G3DSA:2.40.50.100 1 127 2.4E-56 T 11-10-2018 TO73_1778 6f20bdd419a88be121444a2a598a84b7 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 126 1.7E-49 T 11-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TO73_1778 6f20bdd419a88be121444a2a598a84b7 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.795 T 11-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TO73_0657 eaacb18b06ef66cf576b7c34c0b926de 644 SUPERFAMILY SSF56801 9 609 2.88E-116 T 11-10-2018 TO73_0657 eaacb18b06ef66cf576b7c34c0b926de 644 Gene3D G3DSA:3.40.50.12780 329 471 6.7E-37 T 11-10-2018 TO73_0657 eaacb18b06ef66cf576b7c34c0b926de 644 Pfam PF00501 AMP-binding enzyme 24 478 7.6E-88 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_0657 eaacb18b06ef66cf576b7c34c0b926de 644 Gene3D G3DSA:3.40.50.12780 8 305 2.2E-49 T 11-10-2018 TO73_0517 423dfe2f94bb3fdf68210eb885190d6b 264 Gene3D G3DSA:1.10.760.10 51 137 9.2E-22 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0517 423dfe2f94bb3fdf68210eb885190d6b 264 PIRSF PIRSF038455 1 264 9.2E-68 T 11-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 TO73_0517 423dfe2f94bb3fdf68210eb885190d6b 264 SUPERFAMILY SSF46626 150 248 6.8E-26 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0517 423dfe2f94bb3fdf68210eb885190d6b 264 Gene3D G3DSA:1.10.760.10 138 253 1.9E-26 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0517 423dfe2f94bb3fdf68210eb885190d6b 264 SUPERFAMILY SSF46626 41 144 5.79E-22 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TO73_0517 423dfe2f94bb3fdf68210eb885190d6b 264 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 49 256 2.2E-69 T 11-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 TO73_2096 cf490de650b088dde2a45001855bf03c 794 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 43 120 2.4E-5 T 11-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TO73_2096 cf490de650b088dde2a45001855bf03c 794 Gene3D G3DSA:2.120.10.10 487 693 1.5E-6 T 11-10-2018 TO73_2096 cf490de650b088dde2a45001855bf03c 794 SUPERFAMILY SSF50939 485 766 2.35E-12 T 11-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TO73_1157 ec34a6ee4364daf7196a0184ce327743 330 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 3 283 5.9E-86 T 11-10-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB TO73_1157 ec34a6ee4364daf7196a0184ce327743 330 Pfam PF04230 Polysaccharide pyruvyl transferase 13 263 3.9E-37 T 11-10-2018 IPR007345 Polysaccharide pyruvyl transferase TO73_0716 f291f832b923e26943f5d11c7cbe5c38 132 Gene3D G3DSA:3.10.129.10 2 132 6.4E-38 T 11-10-2018 TO73_0716 f291f832b923e26943f5d11c7cbe5c38 132 Pfam PF03061 Thioesterase superfamily 17 100 4.1E-16 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TO73_0716 f291f832b923e26943f5d11c7cbe5c38 132 SUPERFAMILY SSF54637 7 126 1.79E-36 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_0716 f291f832b923e26943f5d11c7cbe5c38 132 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 8 109 5.5E-24 T 11-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 TO73_0716 f291f832b923e26943f5d11c7cbe5c38 132 PIRSF PIRSF003230 2 131 4.5E-33 T 11-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 TO73_0308 d47bbd1e7b431d94eea206047c6f4463 238 SUPERFAMILY SSF52540 17 158 3.31E-9 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0308 d47bbd1e7b431d94eea206047c6f4463 238 Gene3D G3DSA:3.40.50.300 14 191 1.2E-7 T 11-10-2018 TO73_1379 f5624b2d5eb4abbf3b63ae6acc77c25b 243 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 5 215 1.1E-71 T 11-10-2018 IPR013412 CRISPR-associated RAMP Csm3 TO73_1379 f5624b2d5eb4abbf3b63ae6acc77c25b 243 Pfam PF03787 RAMP superfamily 31 213 1.2E-12 T 11-10-2018 IPR005537 CRISPR type III-associated RAMP protein TO73_2369 1f94e0d41f11d9bb10fad122b1e7af76 258 Pfam PF02517 CAAX protease self-immunity 115 219 1.6E-13 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TO73_0243 96c1ae54f7525788825dff111f40a5e6 189 SUPERFAMILY SSF48613 26 187 4.23E-35 T 11-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TO73_0243 96c1ae54f7525788825dff111f40a5e6 189 Gene3D G3DSA:1.20.910.10 3 188 1.0E-40 T 11-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TO73_2713 709f79356106cebdf86746e86654d25f 152 SUPERFAMILY SSF53955 21 147 7.29E-32 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily TO73_2713 709f79356106cebdf86746e86654d25f 152 Pfam PF01464 Transglycosylase SLT domain 31 123 1.5E-17 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 TO73_2713 709f79356106cebdf86746e86654d25f 152 Gene3D G3DSA:1.10.530.10 21 149 2.3E-27 T 11-10-2018 TO73_0622 61fb6a26629be5a682232aeb02306d2c 208 Gene3D G3DSA:3.40.50.2020 1 208 3.2E-81 T 11-10-2018 TO73_0622 61fb6a26629be5a682232aeb02306d2c 208 SUPERFAMILY SSF53271 4 206 4.98E-69 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_0622 61fb6a26629be5a682232aeb02306d2c 208 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 208 5.6E-86 T 11-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TO73_0622 61fb6a26629be5a682232aeb02306d2c 208 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 45.628 T 11-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TO73_0622 61fb6a26629be5a682232aeb02306d2c 208 Pfam PF14681 Uracil phosphoribosyltransferase 6 207 7.5E-73 T 11-10-2018 TO73_1744 b035c430ebe35226c9488bc181b8d2b0 862 Pfam PF01580 FtsK/SpoIIIE family 501 637 1.0E-41 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TO73_1744 b035c430ebe35226c9488bc181b8d2b0 862 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 38 126 2.3E-6 T 11-10-2018 IPR025199 DNA translocase FtsK, 4TM region TO73_1744 b035c430ebe35226c9488bc181b8d2b0 862 Gene3D G3DSA:3.40.50.300 496 772 1.5E-99 T 11-10-2018 TO73_1744 b035c430ebe35226c9488bc181b8d2b0 862 SUPERFAMILY SSF46785 791 856 2.95E-18 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1744 b035c430ebe35226c9488bc181b8d2b0 862 Pfam PF09397 Ftsk gamma domain 793 853 3.2E-24 T 11-10-2018 IPR018541 FtsK gamma domain TO73_1744 b035c430ebe35226c9488bc181b8d2b0 862 SUPERFAMILY SSF52540 473 755 7.1E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1744 b035c430ebe35226c9488bc181b8d2b0 862 SMART SM00843 790 855 9.1E-31 T 11-10-2018 IPR018541 FtsK gamma domain TO73_1744 b035c430ebe35226c9488bc181b8d2b0 862 Gene3D G3DSA:3.30.980.40 390 495 1.2E-34 T 11-10-2018 TO73_1744 b035c430ebe35226c9488bc181b8d2b0 862 Gene3D G3DSA:1.10.10.10 787 851 7.2E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0450 c4fbc60bf30bf0428eb4f837658b35ef 193 Gene3D G3DSA:2.60.130.10 5 160 1.4E-44 T 11-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 TO73_0450 c4fbc60bf30bf0428eb4f837658b35ef 193 SUPERFAMILY SSF49482 18 171 1.01E-44 T 11-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 TO73_0450 c4fbc60bf30bf0428eb4f837658b35ef 193 Pfam PF00775 Dioxygenase 29 118 9.3E-11 T 11-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 TO73_0874 5e8a22d8266ed1d1723baa5ac631cad9 246 Pfam PF01925 Sulfite exporter TauE/SafE 3 237 4.5E-36 T 11-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TO73_0071 9d17d5f2ab252ca322b98fddaa2561bf 76 Gene3D G3DSA:3.60.15.10 29 56 2.3E-9 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_0071 9d17d5f2ab252ca322b98fddaa2561bf 76 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 18 64 3.8E-12 T 11-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TO73_0071 9d17d5f2ab252ca322b98fddaa2561bf 76 SUPERFAMILY SSF56281 18 63 5.14E-9 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_0071 9d17d5f2ab252ca322b98fddaa2561bf 76 Gene3D G3DSA:3.40.50.10890 18 28 2.3E-9 T 11-10-2018 TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 7.7E-17 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 PRINTS PR00149 Fumarate lyase superfamily signature 220 247 7.7E-17 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 PRINTS PR00149 Fumarate lyase superfamily signature 91 109 7.7E-17 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 PRINTS PR00149 Fumarate lyase superfamily signature 262 278 7.7E-17 T 11-10-2018 IPR000362 Fumarate lyase family TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 Gene3D G3DSA:1.20.200.10 108 347 8.1E-84 T 11-10-2018 TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 Pfam PF00206 Lyase 76 287 1.9E-34 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 PRINTS PR00145 Argininosuccinate lyase family signature 90 112 3.3E-23 T 11-10-2018 TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 PRINTS PR00145 Argininosuccinate lyase family signature 220 244 3.3E-23 T 11-10-2018 TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 PRINTS PR00145 Argininosuccinate lyase family signature 131 151 3.3E-23 T 11-10-2018 TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 PRINTS PR00145 Argininosuccinate lyase family signature 262 278 3.3E-23 T 11-10-2018 TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 PRINTS PR00145 Argininosuccinate lyase family signature 182 198 3.3E-23 T 11-10-2018 TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 SUPERFAMILY SSF48557 22 431 1.3E-70 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 Gene3D G3DSA:1.10.40.30 348 376 8.1E-84 T 11-10-2018 TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 Gene3D G3DSA:1.10.275.10 30 218 8.1E-84 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal TO73_0725 7034399bfe7c23c5b66e9c251f720ac0 474 ProSitePatterns PS00163 Fumarate lyases signature. 262 271 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TO73_2204 fbbeaa9e3b7d390cacf95d28ca5a3780 87 Pfam PF04977 Septum formation initiator 15 83 4.1E-12 T 11-10-2018 IPR007060 Septum formation initiator FtsL/DivIC TO73_0893 589a41a26cf8700fec33567c39d5e9d4 413 Gene3D G3DSA:3.40.190.10 16 410 6.6E-67 T 11-10-2018 TO73_0893 589a41a26cf8700fec33567c39d5e9d4 413 Pfam PF13416 Bacterial extracellular solute-binding protein 48 341 8.7E-29 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein TO73_0893 589a41a26cf8700fec33567c39d5e9d4 413 SUPERFAMILY SSF53850 19 409 8.89E-61 T 11-10-2018 TO73_1071 b66300782700329adf3e417e1645b22d 397 Gene3D G3DSA:3.20.20.370 107 208 5.1E-16 T 11-10-2018 TO73_1071 b66300782700329adf3e417e1645b22d 397 Gene3D G3DSA:3.20.20.370 21 105 3.1E-24 T 11-10-2018 TO73_1071 b66300782700329adf3e417e1645b22d 397 SUPERFAMILY SSF88713 25 208 1.41E-45 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TO73_1071 b66300782700329adf3e417e1645b22d 397 Pfam PF01522 Polysaccharide deacetylase 31 100 1.8E-18 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TO73_1248 02975007cefb9276342f74187870c9e8 283 SUPERFAMILY SSF48576 12 281 9.06E-72 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily TO73_1248 02975007cefb9276342f74187870c9e8 283 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 157 182 - T 11-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TO73_1248 02975007cefb9276342f74187870c9e8 283 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 128 143 - T 11-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TO73_1248 02975007cefb9276342f74187870c9e8 283 Pfam PF00494 Squalene/phytoene synthase 20 269 2.8E-62 T 11-10-2018 TO73_1248 02975007cefb9276342f74187870c9e8 283 Gene3D G3DSA:1.10.600.10 7 279 3.7E-77 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily TO73_0816 64a73ed9bda7322d4094a765ba75c5c7 308 Pfam PF03837 RecT family 11 179 8.0E-29 T 11-10-2018 IPR018330 RecT family GO:0003677|GO:0006259 TO73_2043 867eb5c9e678f9f41cb093a9f935f44c 137 Gene3D G3DSA:3.40.50.620 1 137 2.4E-48 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TO73_2043 867eb5c9e678f9f41cb093a9f935f44c 137 SUPERFAMILY SSF52402 3 135 1.72E-34 T 11-10-2018 TO73_0857 76e4dde2387ad682e3ef6ec0dc214de5 253 Gene3D G3DSA:3.20.20.370 4 253 3.9E-103 T 11-10-2018 TO73_0857 76e4dde2387ad682e3ef6ec0dc214de5 253 SUPERFAMILY SSF88713 5 253 5.41E-93 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TO73_0857 76e4dde2387ad682e3ef6ec0dc214de5 253 Pfam PF03746 LamB/YcsF family 6 244 4.8E-96 T 11-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TO73_0857 76e4dde2387ad682e3ef6ec0dc214de5 253 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 4 248 43.489 T 11-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TO73_0721 db71931c7c38446d1020f8417d3e5786 200 Pfam PF01121 Dephospho-CoA kinase 9 181 8.8E-55 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TO73_0721 db71931c7c38446d1020f8417d3e5786 200 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 10 188 1.1E-38 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TO73_0721 db71931c7c38446d1020f8417d3e5786 200 Gene3D G3DSA:3.40.50.300 1 197 1.2E-66 T 11-10-2018 TO73_0721 db71931c7c38446d1020f8417d3e5786 200 SUPERFAMILY SSF52540 8 195 9.42E-35 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0721 db71931c7c38446d1020f8417d3e5786 200 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 8 197 25.334 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TO73_1444 a7923c561a39be76ff5080dd8575c710 514 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 12 511 1.2E-233 T 11-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TO73_1444 a7923c561a39be76ff5080dd8575c710 514 SUPERFAMILY SSF51703 14 510 7.59E-211 T 11-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TO73_1444 a7923c561a39be76ff5080dd8575c710 514 Gene3D G3DSA:3.20.20.240 5 514 5.3E-239 T 11-10-2018 TO73_1444 a7923c561a39be76ff5080dd8575c710 514 Pfam PF01642 Methylmalonyl-CoA mutase 17 508 4.7E-222 T 11-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TO73_2722 5b7768c33247606d719c923d10594827 128 Pfam PF04956 TrbC/VIRB2 family 20 112 2.1E-14 T 11-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 TO73_2408 49d4eb93713db8340dcfc3e6b40c2300 320 SUPERFAMILY SSF51556 3 315 1.47E-50 T 11-10-2018 IPR032466 Metal-dependent hydrolase TO73_2408 49d4eb93713db8340dcfc3e6b40c2300 320 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 5 294 1.7E-44 T 11-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 TO73_2408 49d4eb93713db8340dcfc3e6b40c2300 320 Gene3D G3DSA:3.20.20.140 3 319 3.7E-57 T 11-10-2018 TO73_0356 7157ef95d01cb5aa126cc1e50bf92a4b 440 Hamap MF_00484 Glycogen synthase [glgA]. 1 435 39.832 T 11-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TO73_0356 7157ef95d01cb5aa126cc1e50bf92a4b 440 SUPERFAMILY SSF53756 2 436 9.42E-102 T 11-10-2018 TO73_0356 7157ef95d01cb5aa126cc1e50bf92a4b 440 Pfam PF00534 Glycosyl transferases group 1 258 405 1.9E-15 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 TO73_0356 7157ef95d01cb5aa126cc1e50bf92a4b 440 Gene3D G3DSA:3.40.50.2000 226 417 6.7E-132 T 11-10-2018 TO73_0356 7157ef95d01cb5aa126cc1e50bf92a4b 440 Gene3D G3DSA:3.40.50.2000 3 432 6.7E-132 T 11-10-2018 TO73_0356 7157ef95d01cb5aa126cc1e50bf92a4b 440 Pfam PF08323 Starch synthase catalytic domain 2 212 5.2E-59 T 11-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TO73_0356 7157ef95d01cb5aa126cc1e50bf92a4b 440 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 2 434 1.8E-138 T 11-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TO73_0998 01f92436c00454b48cf01d9641d4e67a 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 81 311 1.5E-26 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_0842 caba52a47b96e34c43ccbffd29a4d85a 182 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TO73_0842 caba52a47b96e34c43ccbffd29a4d85a 182 PRINTS PR00502 NUDIX hydrolase family signature 84 99 1.1E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_0842 caba52a47b96e34c43ccbffd29a4d85a 182 PRINTS PR00502 NUDIX hydrolase family signature 70 84 1.1E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TO73_0842 caba52a47b96e34c43ccbffd29a4d85a 182 Gene3D G3DSA:3.90.79.10 1 182 3.3E-51 T 11-10-2018 TO73_0842 caba52a47b96e34c43ccbffd29a4d85a 182 SUPERFAMILY SSF55811 3 176 3.93E-38 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TO73_0842 caba52a47b96e34c43ccbffd29a4d85a 182 Pfam PF00293 NUDIX domain 45 156 2.3E-14 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TO73_2614 ba7ffd921a7b9e63ad89d717a6ba8048 90 Gene3D G3DSA:3.40.1350.20 1 89 1.0E-31 T 11-10-2018 TO73_2614 ba7ffd921a7b9e63ad89d717a6ba8048 90 SUPERFAMILY SSF160761 6 84 4.97E-35 T 11-10-2018 IPR037262 TTHC002-like TO73_0047 b1ea0c58dc1f2af82ef9066c77ba1663 115 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 4 107 3.7E-25 T 11-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV TO73_1450 6352f457f65aa720d11982c7a67ac8f2 556 Gene3D G3DSA:1.20.1730.10 341 546 2.0E-26 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily TO73_1450 6352f457f65aa720d11982c7a67ac8f2 556 Gene3D G3DSA:1.20.1730.10 7 321 9.8E-37 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily TO73_1450 6352f457f65aa720d11982c7a67ac8f2 556 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 465 485 - T 11-10-2018 IPR018212 Sodium/solute symporter, conserved site TO73_1450 6352f457f65aa720d11982c7a67ac8f2 556 Pfam PF00474 Sodium:solute symporter family 33 297 6.1E-35 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TO73_1450 6352f457f65aa720d11982c7a67ac8f2 556 Pfam PF00474 Sodium:solute symporter family 368 483 2.7E-20 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TO73_1450 6352f457f65aa720d11982c7a67ac8f2 556 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 7 547 8.9E-239 T 11-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily TO73_1944 ec36ce44460f38157afd3e0b497457cf 228 Gene3D G3DSA:3.60.21.10 1 228 6.5E-97 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like TO73_1944 ec36ce44460f38157afd3e0b497457cf 228 SUPERFAMILY SSF56300 4 223 3.21E-41 T 11-10-2018 TO73_1944 ec36ce44460f38157afd3e0b497457cf 228 Pfam PF14582 Metallophosphoesterase, calcineurin superfamily 1 227 3.5E-65 T 11-10-2018 IPR029461 Metallophosphoesterase, TT1561-like TO73_1329 b6500b30a631f66b324f49e13c0d584c 236 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 40 228 2.8E-53 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_1329 b6500b30a631f66b324f49e13c0d584c 236 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 41 228 19.974 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_1329 b6500b30a631f66b324f49e13c0d584c 236 SMART SM01207 44 220 9.5E-78 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_1329 b6500b30a631f66b324f49e13c0d584c 236 Pfam PF02660 Glycerol-3-phosphate acyltransferase 45 219 9.8E-49 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_0113 1a015a06957d0ab43afb231a9374d47a 355 Pfam PF01478 Type IV leader peptidase family 102 205 3.3E-8 T 11-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TO73_0113 1a015a06957d0ab43afb231a9374d47a 355 Pfam PF01478 Type IV leader peptidase family 220 318 1.2E-12 T 11-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TO73_0113 1a015a06957d0ab43afb231a9374d47a 355 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 8 89 6.1E-35 T 11-10-2018 IPR010627 Peptidase A24A, N-terminal TO73_0096 7905d5d4768622d5d5f5bc8bf8cb1072 106 Gene3D G3DSA:2.20.28.160 5 58 2.2E-12 T 11-10-2018 TO73_0096 7905d5d4768622d5d5f5bc8bf8cb1072 106 Gene3D G3DSA:2.20.28.30 60 94 7.4E-6 T 11-10-2018 TO73_1951 a73c95b003172600e57d6ccf30c408d9 278 SUPERFAMILY SSF52096 53 235 6.56E-28 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TO73_1951 a73c95b003172600e57d6ccf30c408d9 278 Pfam PF01972 Serine dehydrogenase proteinase 5 271 5.8E-130 T 11-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 TO73_1951 a73c95b003172600e57d6ccf30c408d9 278 Gene3D G3DSA:3.90.226.10 54 238 3.8E-25 T 11-10-2018 TO73_1006 afe795c609ae8ef1123d2b9a1227bb05 457 Gene3D G3DSA:1.10.10.2840 338 454 8.5E-19 T 11-10-2018 TO73_1006 afe795c609ae8ef1123d2b9a1227bb05 457 Pfam PF13556 PucR C-terminal helix-turn-helix domain 395 451 5.8E-18 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain TO73_0310 5726718dcc61bc370ba68def9ccb977d 82 Pfam PF00801 PKD domain 4 71 3.3E-6 T 11-10-2018 IPR000601 PKD domain TO73_0310 5726718dcc61bc370ba68def9ccb977d 82 Gene3D G3DSA:2.60.40.10 1 79 3.2E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0723 a65da9f2f7a66f297588f699d8bef44f 135 Gene3D G3DSA:3.90.1010.10 1 135 3.9E-43 T 11-10-2018 TO73_0723 a65da9f2f7a66f297588f699d8bef44f 135 SUPERFAMILY SSF82649 3 132 5.75E-20 T 11-10-2018 TO73_0723 a65da9f2f7a66f297588f699d8bef44f 135 Pfam PF02657 Fe-S metabolism associated domain 17 128 4.1E-20 T 11-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like TO73_1235 8b943ce29419156e83e43af16a6f7db1 166 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 154 5.6E-36 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TO73_1235 8b943ce29419156e83e43af16a6f7db1 166 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 157 39.354 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TO73_1235 8b943ce29419156e83e43af16a6f7db1 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 2.2E-25 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TO73_1235 8b943ce29419156e83e43af16a6f7db1 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 110 129 2.2E-25 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TO73_1235 8b943ce29419156e83e43af16a6f7db1 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 86 102 2.2E-25 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TO73_1235 8b943ce29419156e83e43af16a6f7db1 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 64 80 2.2E-25 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TO73_1235 8b943ce29419156e83e43af16a6f7db1 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 142 154 2.2E-25 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TO73_1235 8b943ce29419156e83e43af16a6f7db1 166 Gene3D G3DSA:3.30.420.10 1 166 6.2E-46 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_1235 8b943ce29419156e83e43af16a6f7db1 166 SUPERFAMILY SSF53098 2 159 2.2E-35 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2703 e75048c8c434d133f36ef4d137b3da61 199 Pfam PF04298 Putative neutral zinc metallopeptidase 68 194 1.5E-14 T 11-10-2018 IPR007395 Putative neutral zinc metallopeptidase TO73_2775 e05cee6aa88afe2b529a54a16f7cc388 680 Gene3D G3DSA:3.40.50.300 351 607 1.1E-21 T 11-10-2018 TO73_2775 e05cee6aa88afe2b529a54a16f7cc388 680 SUPERFAMILY SSF52540 220 580 9.02E-25 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2775 e05cee6aa88afe2b529a54a16f7cc388 680 Pfam PF00271 Helicase conserved C-terminal domain 434 549 6.0E-7 T 11-10-2018 IPR001650 Helicase, C-terminal TO73_2775 e05cee6aa88afe2b529a54a16f7cc388 680 SMART SM00487 37 285 2.0E-12 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TO73_2775 e05cee6aa88afe2b529a54a16f7cc388 680 SUPERFAMILY SSF52540 24 291 1.86E-21 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0892 46cc57cebc779e7c8bd6a2eb4f9e7067 367 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 359 2.1E-11 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0892 46cc57cebc779e7c8bd6a2eb4f9e7067 367 SUPERFAMILY SSF161098 54 355 3.35E-49 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1856 60c3f313acafadd9a5091221575b2bee 74 Pfam PF07866 Protein of unknown function (DUF1653) 6 65 9.2E-26 T 11-10-2018 IPR023387 DUF1653-like domain TO73_1856 60c3f313acafadd9a5091221575b2bee 74 Gene3D G3DSA:2.30.30.320 1 74 1.1E-26 T 11-10-2018 IPR037135 DUF1653-like domain superfamily TO73_2855 767a23bf32021f0d5f3762e936fe0130 106 SUPERFAMILY SSF53098 34 106 1.52E-13 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_2855 767a23bf32021f0d5f3762e936fe0130 106 Gene3D G3DSA:3.30.420.10 2 106 8.3E-14 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TO73_0189 486a6565954273cb9310dc7f70fa443c 432 Pfam PF10123 Mu-like prophage I protein 270 388 6.5E-12 T 11-10-2018 IPR012106 Protease, Mu phage/prophage I type TO73_0189 486a6565954273cb9310dc7f70fa443c 432 Pfam PF10123 Mu-like prophage I protein 20 146 2.0E-36 T 11-10-2018 IPR012106 Protease, Mu phage/prophage I type TO73_0189 486a6565954273cb9310dc7f70fa443c 432 PIRSF PIRSF016624 11 147 1.2E-18 T 11-10-2018 IPR012106 Protease, Mu phage/prophage I type TO73_0189 486a6565954273cb9310dc7f70fa443c 432 PIRSF PIRSF016624 261 388 1.0E-4 T 11-10-2018 IPR012106 Protease, Mu phage/prophage I type TO73_2323 5fc818d280746977533b45da2bb2c597 89 Pfam PF00462 Glutaredoxin 8 56 2.1E-9 T 11-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TO73_2323 5fc818d280746977533b45da2bb2c597 89 SUPERFAMILY SSF52833 7 60 6.04E-11 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_2323 5fc818d280746977533b45da2bb2c597 89 Gene3D G3DSA:3.40.30.10 7 88 2.7E-12 T 11-10-2018 TO73_0888 ee09413523fdd20528e0e7ba05ca2a33 432 Pfam PF01964 Radical SAM ThiC family 2 418 9.5E-186 T 11-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TO73_0888 ee09413523fdd20528e0e7ba05ca2a33 432 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 419 2.6E-181 T 11-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TO73_0888 ee09413523fdd20528e0e7ba05ca2a33 432 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 423 88.55 T 11-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TO73_0888 ee09413523fdd20528e0e7ba05ca2a33 432 Gene3D G3DSA:3.20.20.540 43 360 1.5E-137 T 11-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 Pfam PF01316 Arginine repressor, DNA binding domain 3 67 5.0E-25 T 11-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 SUPERFAMILY SSF55252 86 150 9.29E-16 T 11-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 89 130 1.0E-14 T 11-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 Hamap MF_00173 Arginine repressor [argR]. 1 154 56.247 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 TIGRFAM TIGR01529 argR_whole: arginine repressor 6 151 2.6E-50 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 PRINTS PR01467 Bacterial arginine repressor signature 90 103 2.9E-22 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 PRINTS PR01467 Bacterial arginine repressor signature 22 35 2.9E-22 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 PRINTS PR01467 Bacterial arginine repressor signature 38 53 2.9E-22 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 PRINTS PR01467 Bacterial arginine repressor signature 120 135 2.9E-22 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 Pfam PF02863 Arginine repressor, C-terminal domain 85 147 2.4E-21 T 11-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 Gene3D G3DSA:1.10.10.10 5 67 6.0E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 SUPERFAMILY SSF46785 2 67 6.46E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_0431 2094c37dcfec394e0bf23ee9c4f4d5aa 158 Gene3D G3DSA:3.30.1360.40 72 151 8.6E-22 T 11-10-2018 TO73_0559 20c18cdb65829199ff0c4ae26d0876b3 334 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 330 8.5E-101 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TO73_0559 20c18cdb65829199ff0c4ae26d0876b3 334 SMART SM01329 4 327 1.9E-168 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TO73_0559 20c18cdb65829199ff0c4ae26d0876b3 334 Gene3D G3DSA:3.40.718.10 2 334 9.3E-152 T 11-10-2018 TO73_0559 20c18cdb65829199ff0c4ae26d0876b3 334 SUPERFAMILY SSF53659 1 331 7.56E-116 T 11-10-2018 TO73_1957 dae00dc148e83313cf56882838d3af93 182 SUPERFAMILY SSF46458 7 149 1.44E-29 T 11-10-2018 IPR009050 Globin-like superfamily TO73_1957 dae00dc148e83313cf56882838d3af93 182 Gene3D G3DSA:1.10.490.10 7 165 1.6E-35 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TO73_1957 dae00dc148e83313cf56882838d3af93 182 Pfam PF11563 Protoglobin 7 157 1.2E-28 T 11-10-2018 TO73_0254 da32f0a062309baa9e0b47446455e114 449 Pfam PF03916 Polysulphide reductase, NrfD 69 389 2.1E-25 T 11-10-2018 IPR005614 NrfD family TO73_1210 f799843244343772bf88d1d24515651e 298 Pfam PF10124 Mu-like prophage major head subunit gpT 151 225 4.2E-8 T 11-10-2018 IPR018774 Bacteriophage Mu, GpT TO73_1210 f799843244343772bf88d1d24515651e 298 Pfam PF10124 Mu-like prophage major head subunit gpT 232 294 9.4E-20 T 11-10-2018 IPR018774 Bacteriophage Mu, GpT TO73_1210 f799843244343772bf88d1d24515651e 298 Pfam PF10124 Mu-like prophage major head subunit gpT 9 141 9.8E-28 T 11-10-2018 IPR018774 Bacteriophage Mu, GpT TO73_0489 df52cc3b535f6efe5c191fb88e11168e 109 Pfam PF03259 Roadblock/LC7 domain 11 82 1.4E-6 T 11-10-2018 IPR004942 Roadblock/LAMTOR2 domain TO73_0489 df52cc3b535f6efe5c191fb88e11168e 109 SUPERFAMILY SSF103196 10 108 4.45E-9 T 11-10-2018 TO73_0489 df52cc3b535f6efe5c191fb88e11168e 109 SMART SM00960 3 86 0.0011 T 11-10-2018 IPR004942 Roadblock/LAMTOR2 domain TO73_0489 df52cc3b535f6efe5c191fb88e11168e 109 Gene3D G3DSA:3.30.450.30 3 109 7.4E-10 T 11-10-2018 TO73_2417 c4cb05e21a37a5b905b789e3b6df5155 184 SUPERFAMILY SSF52980 2 182 5.09E-20 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_2417 c4cb05e21a37a5b905b789e3b6df5155 184 Pfam PF05685 Putative restriction endonuclease 11 181 9.5E-34 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_2417 c4cb05e21a37a5b905b789e3b6df5155 184 Gene3D G3DSA:3.90.1570.10 2 184 3.9E-15 T 11-10-2018 TO73_2077 2e0d02565c8d5e2129368803e1f03d4a 154 SUPERFAMILY SSF49764 36 152 1.31E-33 T 11-10-2018 IPR008978 HSP20-like chaperone TO73_2077 2e0d02565c8d5e2129368803e1f03d4a 154 Pfam PF00011 Hsp20/alpha crystallin family 53 150 7.4E-21 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TO73_2077 2e0d02565c8d5e2129368803e1f03d4a 154 Gene3D G3DSA:2.60.40.790 11 152 3.3E-34 T 11-10-2018 IPR008978 HSP20-like chaperone TO73_2617 4d2671d92d7b3e2a153ee9952dfb2a3d 397 Pfam PF03090 Replicase family 69 180 4.9E-13 T 11-10-2018 IPR004322 Plasmid replicase, bacterial TO73_2617 4d2671d92d7b3e2a153ee9952dfb2a3d 397 Pfam PF08708 Primase C terminal 1 (PriCT-1) 212 287 1.9E-12 T 11-10-2018 IPR014820 Primase, C-terminal 1 TO73_2617 4d2671d92d7b3e2a153ee9952dfb2a3d 397 Gene3D G3DSA:1.10.340.50 211 300 2.2E-13 T 11-10-2018 TO73_2617 4d2671d92d7b3e2a153ee9952dfb2a3d 397 Gene3D G3DSA:1.10.10.10 341 397 8.5E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1942 6d94716e1ac05a760ed173cf422d023e 394 Pfam PF10116 Protein required for attachment to host cells 142 260 2.5E-6 T 11-10-2018 IPR019291 Host attachment protein TO73_1997 5f255afe059cbc5d2646d4262501162e 302 Pfam PF05067 Manganese containing catalase 1 300 9.6E-79 T 11-10-2018 IPR007760 Manganese catalase TO73_1997 5f255afe059cbc5d2646d4262501162e 302 Gene3D G3DSA:1.20.1260.130 2 302 7.8E-125 T 11-10-2018 TO73_1997 5f255afe059cbc5d2646d4262501162e 302 SUPERFAMILY SSF47240 1 298 5.76E-99 T 11-10-2018 IPR009078 Ferritin-like superfamily TO73_1254 0166d44adc23810b5c8dcc3b56aea0ee 334 Pfam PF00535 Glycosyl transferase family 2 41 150 8.2E-18 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TO73_1254 0166d44adc23810b5c8dcc3b56aea0ee 334 Gene3D G3DSA:3.90.550.10 32 256 7.3E-30 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_1254 0166d44adc23810b5c8dcc3b56aea0ee 334 SUPERFAMILY SSF53448 22 256 4.5E-34 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0205 dc9e36f7d2c7728059daeceefe504559 244 Pfam PF09684 Phage tail protein (Tail_P2_I) 42 167 5.7E-9 T 11-10-2018 IPR006521 Tail protein I TO73_2299 1b13986fca5a2e9f43bc84728de55cb2 256 Pfam PF12730 ABC-2 family transporter protein 6 134 1.6E-13 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TO73_1188 378ad5c065d089249b8b0c162d36f342 91 SUPERFAMILY SSF46785 39 80 8.13E-6 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1017 7cea34b82a59e5d8afe560bc1402debe 220 Pfam PF03824 High-affinity nickel-transport protein 106 189 1.1E-6 T 11-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 TO73_2732 9d790328a901331765f67f4ddee91f7a 308 SUPERFAMILY SSF56731 127 296 1.31E-10 T 11-10-2018 TO73_2732 9d790328a901331765f67f4ddee91f7a 308 Gene3D G3DSA:3.40.1360.10 199 300 3.7E-5 T 11-10-2018 TO73_1849 52532a5e42539240fa79018f1c858de9 234 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 193 1.0E-18 T 11-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TO73_1849 52532a5e42539240fa79018f1c858de9 234 PIRSF PIRSF000883 1 233 1.6E-44 T 11-10-2018 IPR011152 Phosphoesterase MJ0912 TO73_1849 52532a5e42539240fa79018f1c858de9 234 SUPERFAMILY SSF56300 2 229 1.01E-51 T 11-10-2018 TO73_1849 52532a5e42539240fa79018f1c858de9 234 Gene3D G3DSA:3.60.21.10 1 230 3.6E-47 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like TO73_0885 fd39aef67c4d1b4844077b9684a04d1a 64 Gene3D G3DSA:3.10.20.30 1 64 1.2E-27 T 11-10-2018 IPR012675 Beta-grasp domain superfamily TO73_0885 fd39aef67c4d1b4844077b9684a04d1a 64 Pfam PF02597 ThiS family 2 64 2.5E-10 T 11-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TO73_0885 fd39aef67c4d1b4844077b9684a04d1a 64 SUPERFAMILY SSF54285 2 63 9.16E-15 T 11-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TO73_0885 fd39aef67c4d1b4844077b9684a04d1a 64 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 64 2.7E-12 T 11-10-2018 IPR010035 ThiS, thiamine-biosynthesis TO73_2198 988da4153ab9892e3132e3419fa02cf3 118 Gene3D G3DSA:1.10.10.10 1 59 4.8E-15 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2198 988da4153ab9892e3132e3419fa02cf3 118 Gene3D G3DSA:3.30.1490.190 61 117 2.8E-10 T 11-10-2018 TO73_2198 988da4153ab9892e3132e3419fa02cf3 118 Pfam PF01475 Ferric uptake regulator family 1 103 6.3E-19 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TO73_2198 988da4153ab9892e3132e3419fa02cf3 118 SUPERFAMILY SSF46785 1 110 4.84E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1080 8fb931f035bdc1cfb94b6537c87915a3 230 SUPERFAMILY SSF102588 1 219 7.85E-47 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TO73_1080 8fb931f035bdc1cfb94b6537c87915a3 230 Gene3D G3DSA:3.40.50.10320 1 215 2.8E-50 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TO73_1080 8fb931f035bdc1cfb94b6537c87915a3 230 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 125 9.8E-25 T 11-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TO73_1125 5c7ebfae9220fecc8504b1e9e5a2a0d9 179 Gene3D G3DSA:3.40.50.1010 4 167 6.0E-46 T 11-10-2018 TO73_1125 5c7ebfae9220fecc8504b1e9e5a2a0d9 179 Pfam PF01936 NYN domain 11 163 2.0E-34 T 11-10-2018 IPR021139 NYN domain, limkain-b1-type TO73_1212 9bbd69d4cdccfbfb362a9c5993d3300e 161 Pfam PF05069 Phage virion morphogenesis family 21 158 1.1E-26 T 11-10-2018 IPR006522 Phage virion morphogensis protein TO73_1212 9bbd69d4cdccfbfb362a9c5993d3300e 161 TIGRFAM TIGR01635 tail_comp_S: phage virion morphogenesis protein 18 156 2.5E-16 T 11-10-2018 IPR006522 Phage virion morphogensis protein TO73_0286 6f216bfcb97440c9b55b648e12b016ed 94 Gene3D G3DSA:1.20.58.1000 2 94 7.1E-33 T 11-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily TO73_0286 6f216bfcb97440c9b55b648e12b016ed 94 Pfam PF02583 Metal-sensitive transcriptional repressor 13 92 1.9E-22 T 11-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 TO73_1644 8cfb871c19d8971b675e3a111ed97136 421 SUPERFAMILY SSF53474 37 397 2.56E-23 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_1644 8cfb871c19d8971b675e3a111ed97136 421 Pfam PF12146 Serine aminopeptidase, S33 43 167 5.7E-8 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 TO73_1324 49cf1ed7a3ddb02f723d79ca990a0115 381 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 3 381 1.5E-117 T 11-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TO73_1324 49cf1ed7a3ddb02f723d79ca990a0115 381 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 381 3.0E-149 T 11-10-2018 TO73_1324 49cf1ed7a3ddb02f723d79ca990a0115 381 SUPERFAMILY SSF56266 6 377 5.36E-129 T 11-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TO73_1324 49cf1ed7a3ddb02f723d79ca990a0115 381 Pfam PF01960 ArgJ family 11 381 1.7E-131 T 11-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TO73_1324 49cf1ed7a3ddb02f723d79ca990a0115 381 Gene3D G3DSA:3.60.70.12 1 254 7.4E-90 T 11-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TO73_1324 49cf1ed7a3ddb02f723d79ca990a0115 381 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 381 129.105 T 11-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TO73_1324 49cf1ed7a3ddb02f723d79ca990a0115 381 Gene3D G3DSA:3.10.20.340 255 381 2.7E-43 T 11-10-2018 TO73_1693 e662f63f33b305d2111d6ef644bea30e 142 Pfam PF02631 RecX family 32 134 4.2E-21 T 11-10-2018 IPR003783 Regulatory protein RecX GO:0006282 TO73_1693 e662f63f33b305d2111d6ef644bea30e 142 Hamap MF_01114 Regulatory protein RecX [recX]. 2 140 14.117 T 11-10-2018 IPR003783 Regulatory protein RecX GO:0006282 TO73_1693 e662f63f33b305d2111d6ef644bea30e 142 Gene3D G3DSA:1.10.10.10 51 93 5.0E-9 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1693 e662f63f33b305d2111d6ef644bea30e 142 Gene3D G3DSA:1.10.10.10 5 49 6.1E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1430 22c581c813c94c63750b70a828722c74 177 SUPERFAMILY SSF52980 4 174 2.9E-18 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1430 22c581c813c94c63750b70a828722c74 177 Pfam PF05685 Putative restriction endonuclease 9 169 6.6E-29 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1430 22c581c813c94c63750b70a828722c74 177 Gene3D G3DSA:3.90.1570.10 2 176 4.4E-14 T 11-10-2018 TO73_2366 11ff1592007b35ea85e418a491d4a5f6 285 Gene3D G3DSA:3.30.479.30 91 220 3.6E-10 T 11-10-2018 TO73_2366 11ff1592007b35ea85e418a491d4a5f6 285 SUPERFAMILY SSF117892 95 220 1.83E-13 T 11-10-2018 IPR036013 Band 7/SPFH domain superfamily TO73_2366 11ff1592007b35ea85e418a491d4a5f6 285 SMART SM00244 57 218 5.7E-13 T 11-10-2018 IPR001107 Band 7 domain TO73_2366 11ff1592007b35ea85e418a491d4a5f6 285 Pfam PF01145 SPFH domain / Band 7 family 61 227 6.0E-27 T 11-10-2018 IPR001107 Band 7 domain TO73_0365 93398e07661bca7b2f0e09c76aa13572 324 Pfam PF01609 Transposase DDE domain 34 134 6.9E-6 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_0833 d7af6f672aed7459fa024f0d1eb83617 277 Gene3D G3DSA:3.30.1540.10 192 275 3.5E-13 T 11-10-2018 TO73_0833 d7af6f672aed7459fa024f0d1eb83617 277 Pfam PF02515 CoA-transferase family III 198 276 2.1E-7 T 11-10-2018 IPR003673 CoA-transferase family III GO:0003824 TO73_0833 d7af6f672aed7459fa024f0d1eb83617 277 Pfam PF02515 CoA-transferase family III 10 159 1.9E-32 T 11-10-2018 IPR003673 CoA-transferase family III GO:0003824 TO73_0833 d7af6f672aed7459fa024f0d1eb83617 277 SUPERFAMILY SSF89796 10 276 4.58E-58 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily TO73_0833 d7af6f672aed7459fa024f0d1eb83617 277 Gene3D G3DSA:3.40.50.10540 9 191 2.3E-41 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily TO73_1973 cb65a7b61f67543accb552f9edc76864 322 SUPERFAMILY SSF56601 35 281 8.34E-55 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TO73_1973 cb65a7b61f67543accb552f9edc76864 322 Gene3D G3DSA:3.40.710.10 28 318 5.9E-58 T 11-10-2018 TO73_1973 cb65a7b61f67543accb552f9edc76864 322 Pfam PF00144 Beta-lactamase 38 313 8.3E-46 T 11-10-2018 IPR001466 Beta-lactamase-related TO73_0626 6974f6bc1a08b500145fecaff25daa29 61 Pfam PF09360 Iron-binding zinc finger CDGSH type 5 43 2.1E-14 T 11-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TO73_0626 6974f6bc1a08b500145fecaff25daa29 61 Gene3D G3DSA:3.40.5.90 7 59 7.1E-16 T 11-10-2018 TO73_0626 6974f6bc1a08b500145fecaff25daa29 61 SMART SM00704 15 48 1.7E-8 T 11-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TO73_0488 feb82ae1259401242873a27c72d38e71 115 SMART SM00960 1 90 1.4E-16 T 11-10-2018 IPR004942 Roadblock/LAMTOR2 domain TO73_0488 feb82ae1259401242873a27c72d38e71 115 Gene3D G3DSA:3.30.450.30 1 115 8.0E-21 T 11-10-2018 TO73_0488 feb82ae1259401242873a27c72d38e71 115 Pfam PF03259 Roadblock/LC7 domain 3 84 9.8E-13 T 11-10-2018 IPR004942 Roadblock/LAMTOR2 domain TO73_0488 feb82ae1259401242873a27c72d38e71 115 SUPERFAMILY SSF103196 2 114 6.28E-21 T 11-10-2018 TO73_2035 f6841d6de38c9fa92deb7373a150ec89 393 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 24 381 1.2E-129 T 11-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 TO73_2035 f6841d6de38c9fa92deb7373a150ec89 393 Pfam PF00155 Aminotransferase class I and II 40 381 1.5E-66 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TO73_2035 f6841d6de38c9fa92deb7373a150ec89 393 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 8 392 1.5E-177 T 11-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type TO73_2035 f6841d6de38c9fa92deb7373a150ec89 393 Gene3D G3DSA:3.90.1150.10 35 383 2.8E-136 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_2035 f6841d6de38c9fa92deb7373a150ec89 393 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 237 246 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TO73_2035 f6841d6de38c9fa92deb7373a150ec89 393 Gene3D G3DSA:3.40.640.10 55 290 2.8E-136 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_2035 f6841d6de38c9fa92deb7373a150ec89 393 SUPERFAMILY SSF53383 5 391 8.07E-113 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1649 bf93b35dd1253d0ce1d85f9391a921e5 123 SUPERFAMILY SSF46785 28 118 5.36E-28 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1649 bf93b35dd1253d0ce1d85f9391a921e5 123 Gene3D G3DSA:1.10.10.10 6 122 5.2E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_1649 bf93b35dd1253d0ce1d85f9391a921e5 123 SMART SM00418 38 117 3.8E-30 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_1649 bf93b35dd1253d0ce1d85f9391a921e5 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 9.2E-20 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_1649 bf93b35dd1253d0ce1d85f9391a921e5 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 71 9.2E-20 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_1649 bf93b35dd1253d0ce1d85f9391a921e5 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 9.2E-20 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_1649 bf93b35dd1253d0ce1d85f9391a921e5 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 9.2E-20 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_1649 bf93b35dd1253d0ce1d85f9391a921e5 123 Pfam PF01022 Bacterial regulatory protein, arsR family 45 90 5.9E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TO73_1649 bf93b35dd1253d0ce1d85f9391a921e5 123 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 62 80 - T 11-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 TO73_0945 5ee596100653fde598bd8b16908ef3a0 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 256 4.1E-19 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0945 5ee596100653fde598bd8b16908ef3a0 270 SUPERFAMILY SSF161098 2 270 4.02E-66 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0945 5ee596100653fde598bd8b16908ef3a0 270 Gene3D G3DSA:1.10.3720.10 2 261 1.5E-63 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0900 b55908f034c19adbc1edc9ac030d2dff 139 Pfam PF00872 Transposase, Mutator family 2 116 2.5E-13 T 11-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TO73_1273 13dcbc144705506a227a4af77b771a0b 290 Gene3D G3DSA:3.90.1150.10 201 287 1.9E-19 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1273 13dcbc144705506a227a4af77b771a0b 290 PIRSF PIRSF017617 1 290 3.6E-89 T 11-10-2018 IPR023603 Threonine aldolase TO73_1273 13dcbc144705506a227a4af77b771a0b 290 Pfam PF01212 Beta-eliminating lyase 1 237 5.5E-67 T 11-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 TO73_1273 13dcbc144705506a227a4af77b771a0b 290 SUPERFAMILY SSF53383 1 286 1.48E-87 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1273 13dcbc144705506a227a4af77b771a0b 290 Gene3D G3DSA:3.40.640.10 1 198 2.2E-64 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1802 6a24f3f6405bea978c43d8f771f8f677 184 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 175 3.9E-48 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TO73_1802 6a24f3f6405bea978c43d8f771f8f677 184 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 169 31.299 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TO73_1802 6a24f3f6405bea978c43d8f771f8f677 184 Gene3D G3DSA:3.40.50.1470 1 179 2.2E-56 T 11-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TO73_1802 6a24f3f6405bea978c43d8f771f8f677 184 SUPERFAMILY SSF53178 1 177 9.16E-54 T 11-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TO73_1802 6a24f3f6405bea978c43d8f771f8f677 184 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 11-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 TO73_1802 6a24f3f6405bea978c43d8f771f8f677 184 Pfam PF01195 Peptidyl-tRNA hydrolase 3 167 3.4E-49 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TO73_0390 63f405f9aed2708b97d809a32e229983 138 ProSitePatterns PS00053 Ribosomal protein S8 signature. 108 125 - T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0390 63f405f9aed2708b97d809a32e229983 138 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 1 138 32.622 T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0390 63f405f9aed2708b97d809a32e229983 138 Gene3D G3DSA:3.30.1370.30 3 80 2.1E-35 T 11-10-2018 TO73_0390 63f405f9aed2708b97d809a32e229983 138 SUPERFAMILY SSF56047 1 138 1.7E-48 T 11-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0390 63f405f9aed2708b97d809a32e229983 138 Pfam PF00410 Ribosomal protein S8 4 138 2.7E-49 T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TO73_0390 63f405f9aed2708b97d809a32e229983 138 Gene3D G3DSA:3.30.1490.10 81 138 2.0E-28 T 11-10-2018 TO73_1486 bb083cdc2a22cf0d56976425755e2509 436 Gene3D G3DSA:3.30.2290.10 1 208 2.6E-28 T 11-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TO73_1486 bb083cdc2a22cf0d56976425755e2509 436 SUPERFAMILY SSF111283 1 433 1.05E-96 T 11-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TO73_1486 bb083cdc2a22cf0d56976425755e2509 436 Pfam PF01523 Putative modulator of DNA gyrase 20 305 1.3E-54 T 11-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TO73_0863 4a2938e732923a22a0f72ae10f31c3ae 109 Gene3D G3DSA:3.30.460.10 9 102 7.3E-12 T 11-10-2018 TO73_0863 4a2938e732923a22a0f72ae10f31c3ae 109 Pfam PF01909 Nucleotidyltransferase domain 20 62 2.8E-9 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TO73_0863 4a2938e732923a22a0f72ae10f31c3ae 109 SUPERFAMILY SSF81301 6 106 3.97E-16 T 11-10-2018 TO73_1909 9fb08228fe44d141f20ebcbc42db9d2e 354 Pfam PF03787 RAMP superfamily 83 260 1.8E-11 T 11-10-2018 IPR005537 CRISPR type III-associated RAMP protein TO73_1909 9fb08228fe44d141f20ebcbc42db9d2e 354 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 84 260 9.0E-42 T 11-10-2018 IPR010172 CRISPR-associated protein, TM1791 TO73_0204 170cd3397a6351742492f1bdd2c00813 366 Pfam PF04865 Baseplate J-like protein 73 326 7.0E-39 T 11-10-2018 IPR006949 Baseplate protein J-like TO73_1908 5593ed60b30d0ae0a30a16a230a4be71 377 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 6 340 2.6E-60 T 11-10-2018 IPR019016 CRISPR-associated DxTHG protein TO73_1908 5593ed60b30d0ae0a30a16a230a4be71 377 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 77 97 5.0E-5 T 11-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site TO73_1908 5593ed60b30d0ae0a30a16a230a4be71 377 SUPERFAMILY SSF160980 61 106 7.19E-5 T 11-10-2018 TO73_1908 5593ed60b30d0ae0a30a16a230a4be71 377 TIGRFAM TIGR02221 cas_TM1812: CRISPR-associated protein, TM1812 family 26 157 2.6E-27 T 11-10-2018 IPR011742 CRISPR-associated protein, TM1812 TO73_0992 fc4c2234d5469fd7f6c3832780cfa14e 172 Pfam PF14595 Thioredoxin 47 123 1.5E-18 T 11-10-2018 TO73_0992 fc4c2234d5469fd7f6c3832780cfa14e 172 Gene3D G3DSA:3.40.30.10 40 156 5.3E-12 T 11-10-2018 TO73_0992 fc4c2234d5469fd7f6c3832780cfa14e 172 SUPERFAMILY SSF52833 45 122 3.84E-11 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1394 a068a66cfd99a648e9be88a3caf26182 204 Gene3D G3DSA:3.40.50.2020 58 201 1.5E-10 T 11-10-2018 TO73_1394 a068a66cfd99a648e9be88a3caf26182 204 SUPERFAMILY SSF53271 26 197 1.48E-16 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like TO73_1819 55f82ed92ada36b285b2d3d507eb685b 162 SUPERFAMILY SSF109854 3 158 3.51E-28 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TO73_1819 55f82ed92ada36b285b2d3d507eb685b 162 Pfam PF12867 DinB superfamily 24 155 4.5E-12 T 11-10-2018 IPR024775 DinB-like domain TO73_1819 55f82ed92ada36b285b2d3d507eb685b 162 Gene3D G3DSA:1.20.120.450 6 162 7.7E-25 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TO73_1146 1d1feb21c8668dcdeb2d02537da2de2d 285 SUPERFAMILY SSF52833 136 281 1.89E-33 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1146 1d1feb21c8668dcdeb2d02537da2de2d 285 Pfam PF13462 Thioredoxin 139 281 3.2E-23 T 11-10-2018 IPR012336 Thioredoxin-like fold TO73_1146 1d1feb21c8668dcdeb2d02537da2de2d 285 Gene3D G3DSA:3.40.30.10 132 285 3.2E-36 T 11-10-2018 TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 Pfam PF03466 LysR substrate binding domain 86 283 1.4E-30 T 11-10-2018 IPR005119 LysR, substrate-binding TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 SUPERFAMILY SSF53850 88 284 2.53E-27 T 11-10-2018 TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 Gene3D G3DSA:3.40.190.10 114 276 3.1E-41 T 11-10-2018 TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 SUPERFAMILY SSF46785 1 97 4.94E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 Gene3D G3DSA:1.10.10.10 1 88 4.6E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 Gene3D G3DSA:3.40.190.10 156 259 3.1E-41 T 11-10-2018 TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.8E-9 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.8E-9 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.8E-9 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TO73_2202 1196c7ed8d793ee852a7e68e3c389a18 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 1.7E-21 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TO73_1822 3bb95bfbf4d3d38298b109d34a2d2712 117 Pfam PF04304 Protein of unknown function (DUF454) 2 111 9.6E-32 T 11-10-2018 IPR007401 Protein of unknown function DUF454 TO73_1822 3bb95bfbf4d3d38298b109d34a2d2712 117 PIRSF PIRSF016789 1 116 1.9E-27 T 11-10-2018 IPR007401 Protein of unknown function DUF454 TO73_1461 e83488d85376196ec0b2a1593db10062 177 Pfam PF02660 Glycerol-3-phosphate acyltransferase 6 120 1.3E-17 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_1461 e83488d85376196ec0b2a1593db10062 177 SMART SM01207 5 168 4.0E-17 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TO73_2117 e65a2061deb6f774d530506dbfb61798 255 Pfam PF04468 PSP1 C-terminal conserved region 53 134 2.8E-15 T 11-10-2018 IPR007557 PSP1, C-terminal TO73_1148 501809aaf9a0f8fcb49d8f33a1c07fc4 516 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 238 385 6.5E-21 T 11-10-2018 TO73_1148 501809aaf9a0f8fcb49d8f33a1c07fc4 516 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 3 234 1.2E-29 T 11-10-2018 TO73_1148 501809aaf9a0f8fcb49d8f33a1c07fc4 516 Pfam PF05670 Domain of unknown function (DUF814) 403 485 8.8E-25 T 11-10-2018 IPR008532 Domain of unknown function DUF814 TO73_1148 501809aaf9a0f8fcb49d8f33a1c07fc4 516 Gene3D G3DSA:2.30.310.10 1 162 5.7E-19 T 11-10-2018 TO73_1783 38c9a4494f353c833f523fb1397bcfaf 116 Pfam PF01883 Iron-sulfur cluster assembly protein 16 89 1.8E-23 T 11-10-2018 IPR002744 MIP18 family-like TO73_1783 38c9a4494f353c833f523fb1397bcfaf 116 Gene3D G3DSA:3.30.300.130 9 112 1.5E-38 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TO73_1783 38c9a4494f353c833f523fb1397bcfaf 116 SUPERFAMILY SSF117916 14 110 5.89E-34 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TO73_2615 81ad35dd507a032550c7c330b8044680 70 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 1.6E-17 T 11-10-2018 IPR019270 Protein of unknown function DUF2283 TO73_2151 3bdf38c51ff856b9894861f56abc7337 168 SUPERFAMILY SSF160387 45 151 1.22E-11 T 11-10-2018 TO73_2151 3bdf38c51ff856b9894861f56abc7337 168 Pfam PF05573 NosL 30 147 2.1E-8 T 11-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL TO73_0638 046980b5d5d1a97906eab2a521afca98 53 Gene3D G3DSA:1.10.490.110 1 53 5.5E-13 T 11-10-2018 TO73_0638 046980b5d5d1a97906eab2a521afca98 53 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 1 49 2.4E-7 T 11-10-2018 IPR018727 Protein of unknown function DUF2267 TO73_1320 6e93c2e799b9e844446ca79b1072fada 145 Pfam PF04238 Protein of unknown function (DUF420) 8 133 4.2E-40 T 11-10-2018 IPR007352 Protein of unknown function DUF420 TO73_2383 42ef39b14d9761b5e40c8a4b2a83bbd5 132 Gene3D G3DSA:2.20.28.160 1 48 6.4E-6 T 11-10-2018 TO73_1807 ecaf22f310ddad72aaa0161ec5b79439 189 Pfam PF05685 Putative restriction endonuclease 14 167 3.5E-28 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1807 ecaf22f310ddad72aaa0161ec5b79439 189 Gene3D G3DSA:3.90.1570.10 6 181 6.2E-18 T 11-10-2018 TO73_1807 ecaf22f310ddad72aaa0161ec5b79439 189 SUPERFAMILY SSF52980 8 176 7.51E-24 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_0299 59df13715ba299840479fe71da928a8e 380 Pfam PF12704 MacB-like periplasmic core domain 18 225 7.0E-20 T 11-10-2018 IPR025857 MacB-like periplasmic core domain TO73_0299 59df13715ba299840479fe71da928a8e 380 Pfam PF02687 FtsX-like permease family 281 371 2.3E-13 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TO73_1056 be4a9097a7c70983772d6e472bdfd9e4 248 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_1056 be4a9097a7c70983772d6e472bdfd9e4 248 Gene3D G3DSA:3.40.50.300 1 212 4.1E-62 T 11-10-2018 TO73_1056 be4a9097a7c70983772d6e472bdfd9e4 248 SMART SM00382 26 200 1.6E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_1056 be4a9097a7c70983772d6e472bdfd9e4 248 SUPERFAMILY SSF52540 1 216 8.37E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1056 be4a9097a7c70983772d6e472bdfd9e4 248 Pfam PF00005 ABC transporter 18 151 1.0E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0778 168307851b7039a1b9813ca5d8f0bf7b 255 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 60 234 2.5E-58 T 11-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TO73_0778 168307851b7039a1b9813ca5d8f0bf7b 255 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 64 233 1.6E-64 T 11-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TO73_0469 56bdec621993703ced39e67544a0b07c 159 Gene3D G3DSA:2.30.110.10 2 159 1.1E-38 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TO73_0469 56bdec621993703ced39e67544a0b07c 159 SUPERFAMILY SSF50475 1 157 6.38E-40 T 11-10-2018 TO73_0469 56bdec621993703ced39e67544a0b07c 159 Pfam PF01613 Flavin reductase like domain 11 155 7.6E-27 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TO73_0469 56bdec621993703ced39e67544a0b07c 159 SMART SM00903 10 157 1.2E-31 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TO73_1179 54507f501b91a3ce5bd09bffbf69d045 1043 Pfam PF10145 Phage-related minor tail protein 100 297 5.0E-34 T 11-10-2018 IPR010090 Phage tail tape measure protein TO73_1179 54507f501b91a3ce5bd09bffbf69d045 1043 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 57 406 9.0E-72 T 11-10-2018 IPR010090 Phage tail tape measure protein TO73_1123 af61685f3ab75351f8e3f55fc0eb1713 131 SUPERFAMILY SSF50324 3 92 2.09E-11 T 11-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TO73_1123 af61685f3ab75351f8e3f55fc0eb1713 131 Gene3D G3DSA:3.90.80.10 2 102 9.0E-8 T 11-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TO73_0688 76803ded2fe47e44db591e154366d0e3 91 Gene3D G3DSA:3.30.1230.10 1 87 3.4E-22 T 11-10-2018 IPR035931 YlxR-like superfamily TO73_0688 76803ded2fe47e44db591e154366d0e3 91 SUPERFAMILY SSF64376 2 63 2.35E-19 T 11-10-2018 IPR035931 YlxR-like superfamily TO73_0688 76803ded2fe47e44db591e154366d0e3 91 Pfam PF04296 Protein of unknown function (DUF448) 7 65 8.7E-20 T 11-10-2018 IPR007393 Domain of unknown function DUF448 TO73_1665 96f762472c506fcd882f01411d1a01da 272 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 8 75 1.6E-5 T 11-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TO73_1665 96f762472c506fcd882f01411d1a01da 272 SUPERFAMILY SSF55347 1 192 3.27E-13 T 11-10-2018 TO73_2273 4f021b2f3d78881afe365a6d1df7c042 296 SUPERFAMILY SSF53474 19 224 2.63E-32 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_2273 4f021b2f3d78881afe365a6d1df7c042 296 Gene3D G3DSA:3.40.50.1820 33 247 4.9E-29 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0292 5c1e6f75c4e0a790d7c529583c064427 468 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 12 459 6.9E-215 T 11-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 TO73_0292 5c1e6f75c4e0a790d7c529583c064427 468 SUPERFAMILY SSF101960 35 465 6.28E-135 T 11-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TO73_0292 5c1e6f75c4e0a790d7c529583c064427 468 Pfam PF01458 Uncharacterized protein family (UPF0051) 214 439 1.4E-72 T 11-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TO73_2333 e7ac775396f9b674a64efda6bdc9117c 411 Pfam PF00860 Permease family 4 360 4.2E-92 T 11-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TO73_2333 e7ac775396f9b674a64efda6bdc9117c 411 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 4 393 2.3E-109 T 11-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TO73_0490 79f34596e2a5b2efaddb170344ab75a3 124 SUPERFAMILY SSF103196 4 120 1.38E-13 T 11-10-2018 TO73_0490 79f34596e2a5b2efaddb170344ab75a3 124 Gene3D G3DSA:3.30.450.30 1 121 9.5E-10 T 11-10-2018 TO73_2367 5bc9c4358a377d1af94e1dfe6baa0e4f 66 SUPERFAMILY SSF47598 7 53 1.02E-9 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TO73_2367 5bc9c4358a377d1af94e1dfe6baa0e4f 66 Gene3D G3DSA:1.10.1220.10 6 53 6.5E-8 T 11-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TO73_0413 a55fba06a46179fff5f2c653a6bcb5a0 819 Gene3D G3DSA:2.60.40.10 130 222 2.6E-14 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0413 a55fba06a46179fff5f2c653a6bcb5a0 819 Gene3D G3DSA:2.60.40.10 406 498 3.4E-19 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0413 a55fba06a46179fff5f2c653a6bcb5a0 819 Gene3D G3DSA:2.60.40.10 223 304 8.2E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0413 a55fba06a46179fff5f2c653a6bcb5a0 819 Gene3D G3DSA:2.60.40.10 305 404 2.3E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold TO73_0170 a7ab9a7dd2e8c4a7d645ea3a913b5237 377 Gene3D G3DSA:1.10.150.130 64 179 8.1E-22 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal TO73_0170 a7ab9a7dd2e8c4a7d645ea3a913b5237 377 Gene3D G3DSA:1.10.443.10 181 376 7.6E-53 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TO73_0170 a7ab9a7dd2e8c4a7d645ea3a913b5237 377 Pfam PF00589 Phage integrase family 182 365 5.2E-31 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TO73_0170 a7ab9a7dd2e8c4a7d645ea3a913b5237 377 SUPERFAMILY SSF56349 69 370 3.77E-66 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TO73_0138 cc1dbeb1ce4f995bf3dd097956070540 65 Gene3D G3DSA:3.30.160.250 1 65 4.6E-20 T 11-10-2018 TO73_0138 cc1dbeb1ce4f995bf3dd097956070540 65 SUPERFAMILY SSF143100 1 53 3.79E-19 T 11-10-2018 IPR035069 TTHA1013/TTHA0281-like TO73_0138 cc1dbeb1ce4f995bf3dd097956070540 65 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 5 53 3.2E-14 T 11-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system TO73_2182 b2daf89f6aa2abf1d8e96396f49c523f 495 Gene3D G3DSA:3.40.50.1820 14 491 5.0E-95 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_2182 b2daf89f6aa2abf1d8e96396f49c523f 495 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 184 199 - T 11-10-2018 IPR019826 Carboxylesterase type B, active site TO73_2182 b2daf89f6aa2abf1d8e96396f49c523f 495 Pfam PF00135 Carboxylesterase family 19 471 2.1E-63 T 11-10-2018 IPR002018 Carboxylesterase, type B TO73_2182 b2daf89f6aa2abf1d8e96396f49c523f 495 SUPERFAMILY SSF53474 21 487 2.03E-80 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_1090 f98bc57f8f683b5e959c031ca1a180ca 434 Gene3D G3DSA:3.90.1150.10 299 434 2.0E-52 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TO73_1090 f98bc57f8f683b5e959c031ca1a180ca 434 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 15 433 2.9E-194 T 11-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 TO73_1090 f98bc57f8f683b5e959c031ca1a180ca 434 SUPERFAMILY SSF53383 14 433 4.84E-122 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TO73_1090 f98bc57f8f683b5e959c031ca1a180ca 434 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 17 433 5.9E-129 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TO73_1090 f98bc57f8f683b5e959c031ca1a180ca 434 Gene3D G3DSA:3.40.640.10 14 298 5.7E-99 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TO73_1090 f98bc57f8f683b5e959c031ca1a180ca 434 PIRSF PIRSF001434 4 434 3.7E-123 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TO73_1217 85ec62a4252c9f52fa88beaf983e816e 82 Gene3D G3DSA:3.30.2220.10 8 82 1.6E-7 T 11-10-2018 TO73_0061 e0ed92dbf4d184819c26ca432f644cd1 134 PIRSF PIRSF030042 1 134 1.5E-49 T 11-10-2018 IPR016942 Uncharacterised conserved protein UCP030042 TO73_0061 e0ed92dbf4d184819c26ca432f644cd1 134 Pfam PF14340 Domain of unknown function (DUF4395) 3 125 8.2E-31 T 11-10-2018 IPR025508 Domain of unknown function DUF4395 TO73_0355 ee913096bddd7552e5a14f1f6a65e3a6 124 SUPERFAMILY SSF110857 3 122 5.89E-29 T 11-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily TO73_0355 ee913096bddd7552e5a14f1f6a65e3a6 124 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 120 7.6E-27 T 11-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like TO73_0355 ee913096bddd7552e5a14f1f6a65e3a6 124 Gene3D G3DSA:3.10.490.10 2 123 1.7E-27 T 11-10-2018 TO73_1885 61143423f7cb9de12e6bbf069ce9d716 382 SUPERFAMILY SSF48371 152 349 1.76E-21 T 11-10-2018 IPR016024 Armadillo-type fold TO73_1885 61143423f7cb9de12e6bbf069ce9d716 382 Pfam PF13646 HEAT repeats 150 198 2.7E-7 T 11-10-2018 TO73_1885 61143423f7cb9de12e6bbf069ce9d716 382 Gene3D G3DSA:1.25.10.10 85 382 5.3E-19 T 11-10-2018 IPR011989 Armadillo-like helical TO73_2609 63d5916e71c4a1e0a49016927032e10c 388 Gene3D G3DSA:1.10.8.620 241 294 9.6E-60 T 11-10-2018 TO73_2609 63d5916e71c4a1e0a49016927032e10c 388 Pfam PF13354 Beta-lactamase enzyme family 133 231 2.8E-20 T 11-10-2018 TO73_2609 63d5916e71c4a1e0a49016927032e10c 388 Gene3D G3DSA:3.40.710.10 120 360 9.6E-60 T 11-10-2018 TO73_2609 63d5916e71c4a1e0a49016927032e10c 388 SUPERFAMILY SSF56601 117 366 8.02E-27 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TO73_1253 6f3812e4c2697cb2adc1d50a8355fb71 220 SMART SM00563 43 148 1.3E-19 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TO73_1253 6f3812e4c2697cb2adc1d50a8355fb71 220 SUPERFAMILY SSF69593 35 199 2.09E-18 T 11-10-2018 TO73_1253 6f3812e4c2697cb2adc1d50a8355fb71 220 Pfam PF01553 Acyltransferase 37 145 5.9E-13 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TO73_0233 7317f1fc7c1a7b36241a703d636f485d 225 Gene3D G3DSA:3.90.550.10 1 225 3.8E-73 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0233 7317f1fc7c1a7b36241a703d636f485d 225 SUPERFAMILY SSF53448 12 223 5.63E-38 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TO73_0233 7317f1fc7c1a7b36241a703d636f485d 225 Pfam PF12804 MobA-like NTP transferase domain 1 153 5.4E-14 T 11-10-2018 IPR025877 MobA-like NTP transferase TO73_1399 9a038ce12dd705340c67e0a865fc9c32 2664 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 2368 2608 7.3E-22 T 11-10-2018 IPR007452 Translocation and assembly module TamB TO73_0120 243482c977c77f36f9afe3a34c3fa2f2 270 Pfam PF00892 EamA-like transporter family 1 126 4.0E-14 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_0120 243482c977c77f36f9afe3a34c3fa2f2 270 Pfam PF00892 EamA-like transporter family 138 268 2.7E-21 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_0120 243482c977c77f36f9afe3a34c3fa2f2 270 SUPERFAMILY SSF103481 176 268 7.98E-15 T 11-10-2018 TO73_0120 243482c977c77f36f9afe3a34c3fa2f2 270 SUPERFAMILY SSF103481 33 129 3.14E-10 T 11-10-2018 TO73_0675 f1ab55cde619c1d7bbd9ffb82c5f59f3 421 Gene3D G3DSA:1.20.1600.10 13 418 7.3E-27 T 11-10-2018 TO73_0675 f1ab55cde619c1d7bbd9ffb82c5f59f3 421 SUPERFAMILY SSF56954 4 417 2.75E-25 T 11-10-2018 TO73_0675 f1ab55cde619c1d7bbd9ffb82c5f59f3 421 Pfam PF02321 Outer membrane efflux protein 215 414 3.8E-12 T 11-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TO73_1057 298792018f9160b7d8bb26a9b49e5723 249 SUPERFAMILY SSF161098 45 233 2.22E-24 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1057 298792018f9160b7d8bb26a9b49e5723 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 238 1.9E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1057 298792018f9160b7d8bb26a9b49e5723 249 Gene3D G3DSA:1.10.3720.10 45 240 6.5E-19 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2330 8a945103e4e9db5236661ea76abf913d 305 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 258 1.3E-18 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TO73_2330 8a945103e4e9db5236661ea76abf913d 305 Gene3D G3DSA:3.10.180.10 6 295 2.8E-98 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_2330 8a945103e4e9db5236661ea76abf913d 305 SUPERFAMILY SSF54593 3 275 3.47E-44 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_2330 8a945103e4e9db5236661ea76abf913d 305 Gene3D G3DSA:3.10.180.10 66 202 2.8E-98 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TO73_2241 9b4871da2cd19f4e7499130223395291 133 Pfam PF02635 DsrE/DsrF-like family 26 119 4.3E-5 T 11-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein TO73_2241 9b4871da2cd19f4e7499130223395291 133 SUPERFAMILY SSF75169 1 133 6.28E-20 T 11-10-2018 IPR027396 DsrEFH-like TO73_1278 50c5c096130c1beead5891e29fcd7b46 297 Pfam PF03547 Membrane transport protein 5 135 3.5E-9 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TO73_1278 50c5c096130c1beead5891e29fcd7b46 297 Pfam PF03547 Membrane transport protein 155 290 2.9E-16 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TO73_0944 14771a38e457b12a24ef247b923d0654 433 Gene3D G3DSA:3.40.190.10 139 418 5.4E-110 T 11-10-2018 TO73_0944 14771a38e457b12a24ef247b923d0654 433 Gene3D G3DSA:3.40.190.10 26 379 5.4E-110 T 11-10-2018 TO73_0944 14771a38e457b12a24ef247b923d0654 433 SUPERFAMILY SSF53850 23 421 1.09E-75 T 11-10-2018 TO73_0944 14771a38e457b12a24ef247b923d0654 433 Pfam PF13416 Bacterial extracellular solute-binding protein 40 358 9.3E-46 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein TO73_0543 5c6ff18707e4de85b4fdd19cbde4b505 527 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 278 356 4.9E-14 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TO73_0981 1139de41132bfe7dfdade1805f3e2fc6 618 Pfam PF09484 CRISPR-associated protein TM1802 (cas_TM1802) 53 375 4.8E-43 T 11-10-2018 IPR013389 CRISPR-associated protein Cas8b TO73_0981 1139de41132bfe7dfdade1805f3e2fc6 618 Pfam PF09484 CRISPR-associated protein TM1802 (cas_TM1802) 483 598 7.7E-10 T 11-10-2018 IPR013389 CRISPR-associated protein Cas8b TO73_2801 a009e513fa1beb59afa80e5acce1b132 350 Gene3D G3DSA:3.40.50.300 3 81 3.5E-6 T 11-10-2018 TO73_2265 37475a2e61b0d230d105ee5254ba2405 266 Pfam PF14332 Domain of unknown function (DUF4388) 10 93 8.2E-12 T 11-10-2018 IPR025497 Domain of unknown function DUF4388 TO73_1671 087f51626ed5d34a73d6ae7f1119e7c2 213 Pfam PF01609 Transposase DDE domain 6 172 9.2E-12 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_1671 087f51626ed5d34a73d6ae7f1119e7c2 213 SUPERFAMILY SSF53098 17 179 7.59E-10 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_1941 20a3de76c8c5097a3299b6a0a9cc26dc 129 Pfam PF02915 Rubrerythrin 5 63 7.8E-5 T 11-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TO73_1941 20a3de76c8c5097a3299b6a0a9cc26dc 129 Gene3D G3DSA:1.20.1260.10 2 125 2.0E-5 T 11-10-2018 IPR012347 Ferritin-like TO73_1941 20a3de76c8c5097a3299b6a0a9cc26dc 129 SUPERFAMILY SSF47240 2 125 1.32E-9 T 11-10-2018 IPR009078 Ferritin-like superfamily TO73_0930 27db86719eef124c0adc244fc752cb65 256 Pfam PF12697 Alpha/beta hydrolase family 14 245 1.5E-15 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_0930 27db86719eef124c0adc244fc752cb65 256 PRINTS PR00412 Epoxide hydrolase signature 94 107 5.8E-6 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TO73_0930 27db86719eef124c0adc244fc752cb65 256 PRINTS PR00412 Epoxide hydrolase signature 228 250 5.8E-6 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TO73_0930 27db86719eef124c0adc244fc752cb65 256 PRINTS PR00412 Epoxide hydrolase signature 36 51 5.8E-6 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TO73_0930 27db86719eef124c0adc244fc752cb65 256 Gene3D G3DSA:3.40.50.1820 1 253 1.6E-58 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0930 27db86719eef124c0adc244fc752cb65 256 SUPERFAMILY SSF53474 1 252 1.28E-58 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0930 27db86719eef124c0adc244fc752cb65 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.2E-10 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_0930 27db86719eef124c0adc244fc752cb65 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 36 51 2.2E-10 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_0930 27db86719eef124c0adc244fc752cb65 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 2.2E-10 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_0930 27db86719eef124c0adc244fc752cb65 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 93 2.2E-10 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_1257 596849b3ea26e8a104ab780dbd25e6ae 320 Pfam PF08349 Protein of unknown function (DUF1722) 195 311 4.4E-34 T 11-10-2018 IPR013560 Domain of unknown function DUF1722 TO73_1257 596849b3ea26e8a104ab780dbd25e6ae 320 Pfam PF04463 Protein of unknown function (DUF523) 17 156 1.3E-31 T 11-10-2018 IPR007553 Domain of unknown function DUF523 TO73_1257 596849b3ea26e8a104ab780dbd25e6ae 320 PIRSF PIRSF037004 8 320 1.9E-107 T 11-10-2018 IPR017087 Uncharacterised conserved protein UCP037004 TO73_1420 13c34df82c9607b88b65101b3468abe0 66 Pfam PF10047 Protein of unknown function (DUF2281) 6 35 4.2E-8 T 11-10-2018 IPR018739 Domain of unknown function DUF2281 TO73_1938 d74f4d4874e4fe27359ebbbaa50b5d1d 79 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 26 1.2E-8 T 11-10-2018 IPR025161 Putative transposase IS4/IS5 family TO73_1918 d74f4d4874e4fe27359ebbbaa50b5d1d 79 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 26 1.2E-8 T 11-10-2018 IPR025161 Putative transposase IS4/IS5 family TO73_1345 c741c2d1150f73a2531ba558080c4f0a 156 Pfam PF03741 Integral membrane protein TerC family 38 112 1.9E-18 T 11-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TO73_0408 a7e37c7acda334e957dfbdfb747c0692 225 SUPERFAMILY SSF51445 104 204 2.43E-14 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily TO73_0408 a7e37c7acda334e957dfbdfb747c0692 225 Gene3D G3DSA:3.20.20.80 108 209 6.0E-20 T 11-10-2018 TO73_0408 a7e37c7acda334e957dfbdfb747c0692 225 Pfam PF00128 Alpha amylase, catalytic domain 176 201 4.6E-5 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TO73_1205 82e0fde5fce59b01660d850370fffcac 87 Gene3D G3DSA:1.10.260.40 9 85 4.2E-9 T 11-10-2018 TO73_1205 82e0fde5fce59b01660d850370fffcac 87 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 10 63 6.8E-8 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TO73_1205 82e0fde5fce59b01660d850370fffcac 87 SMART SM00530 10 67 2.3E-5 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TO73_1205 82e0fde5fce59b01660d850370fffcac 87 SUPERFAMILY SSF47413 9 63 2.6E-9 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TO73_0790 d9f39f3ce51e3eed9ab02d65e94b333d 407 Gene3D G3DSA:3.40.50.410 216 390 1.5E-15 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TO73_0790 d9f39f3ce51e3eed9ab02d65e94b333d 407 SUPERFAMILY SSF53300 219 386 5.72E-15 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TO73_0790 d9f39f3ce51e3eed9ab02d65e94b333d 407 Pfam PF13519 von Willebrand factor type A domain 219 317 3.0E-7 T 11-10-2018 IPR002035 von Willebrand factor, type A TO73_2246 3223f5cd5e5615d30c53fe708c423655 315 Pfam PF01609 Transposase DDE domain 68 274 3.1E-12 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_2246 3223f5cd5e5615d30c53fe708c423655 315 SUPERFAMILY SSF53098 9 281 3.03E-16 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_0201 ff187dd8624b74382718c105f839502c 223 SUPERFAMILY SSF69279 56 155 2.0E-5 T 11-10-2018 TO73_0931 280fad76ff2c996ff7d460d41e5976d9 243 Gene3D G3DSA:3.40.50.1820 1 242 3.6E-50 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_0931 280fad76ff2c996ff7d460d41e5976d9 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 184 198 8.9E-10 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_0931 280fad76ff2c996ff7d460d41e5976d9 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 8.9E-10 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_0931 280fad76ff2c996ff7d460d41e5976d9 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 36 51 8.9E-10 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_0931 280fad76ff2c996ff7d460d41e5976d9 243 Pfam PF12697 Alpha/beta hydrolase family 13 230 7.3E-26 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TO73_0931 280fad76ff2c996ff7d460d41e5976d9 243 SUPERFAMILY SSF53474 2 240 3.41E-50 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold TO73_1511 ee7d88071c8740afedac8760742eafdf 134 Pfam PF03061 Thioesterase superfamily 42 119 2.0E-16 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TO73_1511 ee7d88071c8740afedac8760742eafdf 134 SUPERFAMILY SSF54637 6 129 1.29E-31 T 11-10-2018 IPR029069 HotDog domain superfamily TO73_1511 ee7d88071c8740afedac8760742eafdf 134 Gene3D G3DSA:3.10.129.10 2 133 1.5E-50 T 11-10-2018 TO73_1511 ee7d88071c8740afedac8760742eafdf 134 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 13 127 3.2E-34 T 11-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TO73_1244 85742aeb0b3c23481927ff747610fdbb 401 Pfam PF04143 Sulphur transport 43 371 7.9E-66 T 11-10-2018 IPR007272 Sulphur transport domain TO73_0596 c720404b80e74761d179c60b84e7e146 339 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 51 1.5E-11 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TO73_0596 c720404b80e74761d179c60b84e7e146 339 Gene3D G3DSA:1.10.3720.10 129 335 4.4E-26 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0596 c720404b80e74761d179c60b84e7e146 339 SUPERFAMILY SSF161098 133 323 1.96E-32 T 11-10-2018 IPR035906 MetI-like superfamily TO73_0596 c720404b80e74761d179c60b84e7e146 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 156 338 1.3E-29 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_0864 1c5df5bf021c9bea4c1bc61df8f218d0 284 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 3 249 9.0E-61 T 11-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TO73_0864 1c5df5bf021c9bea4c1bc61df8f218d0 284 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 284 75.538 T 11-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TO73_0864 1c5df5bf021c9bea4c1bc61df8f218d0 284 Pfam PF03186 CobD/Cbib protein 3 251 2.6E-80 T 11-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TO73_1493 a946b04372ba26b1ed0ee96402593722 158 SUPERFAMILY SSF52980 12 145 4.34E-22 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1493 a946b04372ba26b1ed0ee96402593722 158 Pfam PF05685 Putative restriction endonuclease 9 146 2.0E-17 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1493 a946b04372ba26b1ed0ee96402593722 158 Gene3D G3DSA:3.90.1570.10 1 158 4.0E-13 T 11-10-2018 TO73_1616 b566a6f27d327d2ae6a9489e6068033e 352 SUPERFAMILY SSF143100 5 65 5.62E-5 T 11-10-2018 IPR035069 TTHA1013/TTHA0281-like TO73_1616 b566a6f27d327d2ae6a9489e6068033e 352 Gene3D G3DSA:3.40.1350.10 218 348 5.0E-5 T 11-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TO73_1616 b566a6f27d327d2ae6a9489e6068033e 352 Gene3D G3DSA:3.30.160.250 1 75 2.8E-12 T 11-10-2018 TO73_1616 b566a6f27d327d2ae6a9489e6068033e 352 SUPERFAMILY SSF52980 101 338 1.97E-27 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1864 48d317b4201c22b92eade256bf463c50 327 SUPERFAMILY SSF161098 91 313 7.06E-13 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1864 48d317b4201c22b92eade256bf463c50 327 Gene3D G3DSA:1.10.3720.10 79 326 4.6E-16 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1864 48d317b4201c22b92eade256bf463c50 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 326 1.3E-31 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_1586 105da67fbdc984f95b988498aaa17f56 95 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 95 18.169 T 11-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 TO73_1586 105da67fbdc984f95b988498aaa17f56 95 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 3 90 5.3E-22 T 11-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TO73_2118 5212a8bdbc3d2dde8da2a59796885239 269 SUPERFAMILY SSF52540 28 169 1.15E-25 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2118 5212a8bdbc3d2dde8da2a59796885239 269 Pfam PF13177 DNA polymerase III, delta subunit 61 158 6.2E-19 T 11-10-2018 TO73_2118 5212a8bdbc3d2dde8da2a59796885239 269 Gene3D G3DSA:3.40.50.300 2 157 1.4E-26 T 11-10-2018 TO73_2818 d00c60f0af74b2d259d0c08c53a6b4bd 323 Gene3D G3DSA:1.20.5.340 122 215 3.8E-5 T 11-10-2018 TO73_1564 d94afa17cb6f3d6004f5a79de25cef1f 234 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 58 224 1.1E-35 T 11-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TO73_1564 d94afa17cb6f3d6004f5a79de25cef1f 234 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 59 218 8.5E-50 T 11-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TO73_1302 ac896d8d7b6fb8fcaf4ed48b4c2407c4 311 SUPERFAMILY SSF110581 34 307 4.05E-89 T 11-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TO73_1302 ac896d8d7b6fb8fcaf4ed48b4c2407c4 311 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 4 309 35.7 T 11-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TO73_1302 ac896d8d7b6fb8fcaf4ed48b4c2407c4 311 Pfam PF04227 Indigoidine synthase A like protein 34 305 3.8E-96 T 11-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TO73_1302 ac896d8d7b6fb8fcaf4ed48b4c2407c4 311 Gene3D G3DSA:3.40.1790.10 31 311 1.2E-95 T 11-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TO73_1143 8d1cc387486f543d1fb5628a8b904b50 94 Gene3D G3DSA:3.40.250.10 1 92 2.0E-19 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_1143 8d1cc387486f543d1fb5628a8b904b50 94 SUPERFAMILY SSF52821 3 90 5.33E-14 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily TO73_2773 75a6ca1805b9f182cfbd904821e2ca68 106 Gene3D G3DSA:2.10.230.10 3 51 4.1E-5 T 11-10-2018 TO73_2773 75a6ca1805b9f182cfbd904821e2ca68 106 SUPERFAMILY SSF57938 8 47 4.58E-6 T 11-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TO73_0192 14028a00cf41c7613683101eecece1b4 173 Pfam PF05069 Phage virion morphogenesis family 13 148 1.3E-15 T 11-10-2018 IPR006522 Phage virion morphogensis protein TO73_0530 b5b2e2be6bcffb85981669b686730b44 140 Pfam PF03918 Cytochrome C biogenesis protein 22 136 8.1E-33 T 11-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family TO73_0530 b5b2e2be6bcffb85981669b686730b44 140 Gene3D G3DSA:1.10.8.640 18 91 1.1E-25 T 11-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily TO73_0838 7a279e93087761ec87c4c1004e3cb0e6 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 334 5.3E-36 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_1309 58adf2f4a8525bff659e3715050f14d2 124 SUPERFAMILY SSF52172 9 120 2.91E-7 T 11-10-2018 IPR011006 CheY-like superfamily TO73_1309 58adf2f4a8525bff659e3715050f14d2 124 Gene3D G3DSA:3.40.50.2300 7 122 3.4E-8 T 11-10-2018 TO73_0961 58b2fd1a82e3bf23c4af4de0bf3ac0ca 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 330 3.0E-42 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_1498 842930b1d592fcef808867a6b8f586b1 292 SUPERFAMILY SSF51971 8 291 1.18E-7 T 11-10-2018 TO73_1390 8f3449303b9f24493377acd5c20240d7 336 Pfam PF07907 YibE/F-like protein 83 320 3.7E-66 T 11-10-2018 IPR012507 YibE/F-like TO73_1215 12a7c8245b80fa58aa34a2926fb31b52 473 Pfam PF10758 Protein of unknown function (DUF2586) 178 408 2.2E-13 T 11-10-2018 IPR019694 Bacteriophage HP1, Orf23 TO73_2806 e387a2b4fe35e7963c91666f018230a7 361 SUPERFAMILY SSF46785 58 92 2.33E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1720 318bedd8c6de23e2ea9b876eeb6082be 161 SUPERFAMILY SSF52833 17 157 3.11E-34 T 11-10-2018 IPR036249 Thioredoxin-like superfamily TO73_1720 318bedd8c6de23e2ea9b876eeb6082be 161 Gene3D G3DSA:3.40.30.10 19 160 1.5E-31 T 11-10-2018 TO73_1720 318bedd8c6de23e2ea9b876eeb6082be 161 Pfam PF00578 AhpC/TSA family 21 137 5.7E-25 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TO73_0219 bb2758c7853620ab8100513dd81b3dd6 365 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 66 208 2.1E-27 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TO73_0219 bb2758c7853620ab8100513dd81b3dd6 365 Gene3D G3DSA:1.10.260.150 51 275 1.6E-42 T 11-10-2018 TO73_0219 bb2758c7853620ab8100513dd81b3dd6 365 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 66 208 1.9E-27 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TO73_1789 d689d2020e93b5a4315b955432a07f62 384 Gene3D G3DSA:3.90.1570.30 3 149 1.0E-6 T 11-10-2018 TO73_1252 89ec3ae29d95d3ed4a318b3a510469f7 232 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 128 218 7.3E-20 T 11-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 TO73_1252 89ec3ae29d95d3ed4a318b3a510469f7 232 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 1 85 4.1E-23 T 11-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 TO73_1407 f7dd902c50af0ac026480d48bddf4e90 102 SUPERFAMILY SSF103007 4 93 1.44E-21 T 11-10-2018 IPR036746 TT1725-like superfamily TO73_1407 f7dd902c50af0ac026480d48bddf4e90 102 Gene3D G3DSA:3.30.70.1120 1 102 5.7E-37 T 11-10-2018 IPR036746 TT1725-like superfamily TO73_1407 f7dd902c50af0ac026480d48bddf4e90 102 Pfam PF04456 Protein of unknown function (DUF503) 7 87 1.1E-18 T 11-10-2018 IPR007546 Protein of unknown function DUF503 TO73_0019 bd19d2d337397bfb27736110f284a532 481 SUPERFAMILY SSF48452 15 169 6.12E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0019 bd19d2d337397bfb27736110f284a532 481 Gene3D G3DSA:1.25.40.10 5 103 1.1E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0019 bd19d2d337397bfb27736110f284a532 481 Gene3D G3DSA:1.25.40.10 104 237 2.1E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_2088 2e03c7cb06b82b7a9f4f8252f05c9ca6 336 Gene3D G3DSA:1.10.3720.10 90 328 9.6E-24 T 11-10-2018 IPR035906 MetI-like superfamily TO73_2088 2e03c7cb06b82b7a9f4f8252f05c9ca6 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 335 5.7E-43 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TO73_2088 2e03c7cb06b82b7a9f4f8252f05c9ca6 336 SUPERFAMILY SSF161098 96 319 8.18E-18 T 11-10-2018 IPR035906 MetI-like superfamily TO73_1526 e27bae89e6239012295fbab3715a6791 224 Pfam PF01882 Protein of unknown function DUF58 26 100 2.3E-16 T 11-10-2018 IPR002881 Domain of unknown function DUF58 TO73_1050 70ec6e1bf2ffbda8cbd49e47a95d9cde 82 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 9 74 6.1E-6 T 11-10-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 TO73_0763 69a0e4021bc38dac5fee6d3c206db83a 368 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 364 1.4E-59 T 11-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 TO73_0163 b680eace9280a20791ff597f3d952d91 92 SUPERFAMILY SSF54786 2 43 3.92E-5 T 11-10-2018 TO73_0191 4c3fc814124dc3361eaf482ed2e849d0 94 Pfam PF07030 Protein of unknown function (DUF1320) 2 83 8.8E-18 T 11-10-2018 IPR009752 Bacteriophage Mu, Gp36 TO73_1841 7f0aa450d80f91b2c9c2513a005f110f 475 Pfam PF03477 ATP cone domain 95 162 2.9E-5 T 11-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TO73_1841 7f0aa450d80f91b2c9c2513a005f110f 475 Pfam PF03477 ATP cone domain 182 256 2.6E-5 T 11-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TO73_1841 7f0aa450d80f91b2c9c2513a005f110f 475 Gene3D G3DSA:3.40.50.300 256 460 3.0E-9 T 11-10-2018 TO73_1841 7f0aa450d80f91b2c9c2513a005f110f 475 SUPERFAMILY SSF52540 259 460 3.33E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0984 2aceca23a7f3370e980b9c7ae4725a16 173 Pfam PF01930 Domain of unknown function DUF83 9 167 1.4E-43 T 11-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 TO73_0984 2aceca23a7f3370e980b9c7ae4725a16 173 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 18 166 3.1E-21 T 11-10-2018 IPR013343 CRISPR-associated protein Cas4 TO73_0349 239e4b0f4e0257297e553bd7218f7d00 157 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 7 156 7.8E-29 T 11-10-2018 IPR017516 AbrB duplication TO73_0349 239e4b0f4e0257297e553bd7218f7d00 157 Pfam PF05145 Transition state regulatory protein AbrB 9 156 2.4E-22 T 11-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 TO73_1763 34d10d559cbb5fa8d502aeaa36905015 69 Gene3D G3DSA:3.30.70.100 1 66 1.5E-8 T 11-10-2018 TO73_2851 cd9a0da494e1e9768f7ef8bdfc39fbf0 600 SMART SM00752 22 289 3.9E-5 T 11-10-2018 IPR011020 HTTM Reactome: R-HSA-159740 TO73_2851 cd9a0da494e1e9768f7ef8bdfc39fbf0 600 Pfam PF04134 Protein of unknown function, DUF393 308 403 2.2E-7 T 11-10-2018 IPR007263 Protein of unknown function DUF393 TO73_1191 ebb23575bc622591d7c0e9304faaa3eb 284 Pfam PF09339 IclR helix-turn-helix domain 224 271 1.9E-12 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TO73_1191 ebb23575bc622591d7c0e9304faaa3eb 284 SUPERFAMILY SSF46785 224 275 1.26E-11 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1191 ebb23575bc622591d7c0e9304faaa3eb 284 ProSitePatterns PS00519 AsnC-type HTH domain signature. 241 267 - T 11-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TO73_1191 ebb23575bc622591d7c0e9304faaa3eb 284 Gene3D G3DSA:1.10.10.10 215 281 5.6E-13 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_0298 e3f33883a57c670069122f1f205f640d 230 Gene3D G3DSA:3.40.50.300 1 229 8.4E-67 T 11-10-2018 TO73_0298 e3f33883a57c670069122f1f205f640d 230 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TO73_0298 e3f33883a57c670069122f1f205f640d 230 Pfam PF00005 ABC transporter 32 168 3.8E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TO73_0298 e3f33883a57c670069122f1f205f640d 230 SUPERFAMILY SSF52540 1 219 4.09E-65 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_0298 e3f33883a57c670069122f1f205f640d 230 SMART SM00382 29 215 1.1E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain TO73_0011 f0f81dfac690861db24de30d1162292a 220 Pfam PF04012 PspA/IM30 family 2 218 7.4E-49 T 11-10-2018 IPR007157 PspA/IM30 TO73_1110 b6d3d230df157498a4279a4c8c13d7ba 67 Pfam PF13453 Transcription factor zinc-finger 1 32 3.4E-14 T 11-10-2018 IPR027392 Transcription factor zinc-finger TO73_1409 67079245908a4e7a06957261c4548aea 86 Pfam PF13711 Domain of unknown function (DUF4160) 9 71 2.7E-20 T 11-10-2018 IPR025427 Protein of unknown function DUF4160 TO73_0811 81223d9ea3f234af4283869940daab7e 108 SUPERFAMILY SSF52980 10 62 1.88E-5 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_0811 81223d9ea3f234af4283869940daab7e 108 Gene3D G3DSA:3.40.1350.10 3 69 5.2E-8 T 11-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TO73_2178 95908a7173e60b3721bb84abb5dfa36f 497 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 487 3.0E-110 T 11-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TO73_1660 13c21ffbffa064751abd18e5dda22416 219 Pfam PF02163 Peptidase family M50 130 187 7.1E-8 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TO73_2301 c3fb898f5b883821989657051ffa10e0 333 Gene3D G3DSA:4.10.320.10 5 48 1.7E-15 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TO73_2301 c3fb898f5b883821989657051ffa10e0 333 Pfam PF02817 e3 binding domain 5 39 3.8E-13 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TO73_2301 c3fb898f5b883821989657051ffa10e0 333 SUPERFAMILY SSF47005 4 43 2.35E-10 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TO73_0109 30ae12999227e07dc25d1f29488f9a78 316 Pfam PF01867 CRISPR associated protein Cas1 3 270 9.6E-70 T 11-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TO73_0109 30ae12999227e07dc25d1f29488f9a78 316 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 2 310 1.5E-66 T 11-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TO73_0109 30ae12999227e07dc25d1f29488f9a78 316 Gene3D G3DSA:3.100.10.20 1 75 1.0E-14 T 11-10-2018 TO73_0109 30ae12999227e07dc25d1f29488f9a78 316 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 300 24.942 T 11-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TO73_0109 30ae12999227e07dc25d1f29488f9a78 316 Gene3D G3DSA:1.20.120.920 85 314 3.1E-67 T 11-10-2018 TO73_0989 58a277652b7c0c7bdf9eb128cb8dc6aa 252 PIRSF PIRSF037834 3 252 1.3E-94 T 11-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 TO73_0989 58a277652b7c0c7bdf9eb128cb8dc6aa 252 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 17 252 4.7E-85 T 11-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 TO73_0989 58a277652b7c0c7bdf9eb128cb8dc6aa 252 Gene3D G3DSA:1.20.1260.10 3 252 4.7E-83 T 11-10-2018 IPR012347 Ferritin-like TO73_0989 58a277652b7c0c7bdf9eb128cb8dc6aa 252 Pfam PF05138 Phenylacetic acid catabolic protein 7 249 1.6E-75 T 11-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 TO73_0989 58a277652b7c0c7bdf9eb128cb8dc6aa 252 SUPERFAMILY SSF47240 8 244 1.37E-73 T 11-10-2018 IPR009078 Ferritin-like superfamily TO73_0776 5f102ecb0d57c66b443285b844caa8e3 449 Pfam PF04932 O-Antigen ligase 205 367 4.0E-8 T 11-10-2018 IPR007016 O-antigen ligase-related TO73_2127 0277c9befd8fa157867c33f0a701349b 51 Pfam PF14110 Domain of unknown function (DUF4282) 5 43 5.4E-8 T 11-10-2018 IPR025557 Protein of unknown function DUF4282 TO73_1692 f1028ce3c5964c4959f9e7328821ad27 145 SUPERFAMILY SSF55961 1 141 1.02E-28 T 11-10-2018 TO73_1692 f1028ce3c5964c4959f9e7328821ad27 145 Gene3D G3DSA:3.30.530.20 1 145 8.5E-42 T 11-10-2018 IPR023393 START-like domain superfamily TO73_1692 f1028ce3c5964c4959f9e7328821ad27 145 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 1.3E-17 T 11-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 TO73_0482 561a4552eedca0eacc238817f745c2df 157 Pfam PF02643 Uncharacterized ACR, COG1430 56 148 3.0E-10 T 11-10-2018 IPR003795 Protein of unknown function DUF192 TO73_0482 561a4552eedca0eacc238817f745c2df 157 Gene3D G3DSA:2.60.120.1140 37 148 1.9E-9 T 11-10-2018 IPR038695 Saro_0823-like superfamily TO73_2219 3c0a178b9291e2524cbf37f9264e228a 298 SMART SM00943 14 171 4.8E-35 T 11-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TO73_2219 3c0a178b9291e2524cbf37f9264e228a 298 SUPERFAMILY SSF56747 9 181 6.21E-32 T 11-10-2018 TO73_2219 3c0a178b9291e2524cbf37f9264e228a 298 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 14 165 5.1E-31 T 11-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TO73_2606 1830feafbbd547fe07001ab1a36e4bf5 280 SUPERFAMILY SSF102114 1 184 3.53E-9 T 11-10-2018 TO73_0523 11d910bc5fdbf1ab6210095d5c3ba9d7 222 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 8 200 1.3E-45 T 11-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 TO73_1538 167c0a38a0e704b4cf6ec0eff22d0ab6 121 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 2 104 6.5E-18 T 11-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1538 167c0a38a0e704b4cf6ec0eff22d0ab6 121 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2 101 3.4E-18 T 11-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1538 167c0a38a0e704b4cf6ec0eff22d0ab6 121 PIRSF PIRSF000178 6 111 6.8E-8 T 11-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1538 167c0a38a0e704b4cf6ec0eff22d0ab6 121 SUPERFAMILY SSF81343 2 108 3.27E-21 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_1538 167c0a38a0e704b4cf6ec0eff22d0ab6 121 Gene3D G3DSA:1.20.1300.10 2 110 3.4E-15 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TO73_0963 d183d06158ebf09d616eddaa1bb8d079 912 Gene3D G3DSA:2.60.40.740 207 362 1.8E-5 T 11-10-2018 TO73_0963 d183d06158ebf09d616eddaa1bb8d079 912 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 803 849 5.2E-13 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0963 d183d06158ebf09d616eddaa1bb8d079 912 Pfam PF01345 Domain of unknown function DUF11 804 883 1.6E-8 T 11-10-2018 IPR001434 Domain of unknown function DUF11 TO73_0021 d23ffdbb7f914a1a6953619a8407a93e 194 Gene3D G3DSA:1.25.40.10 126 192 3.4E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0021 d23ffdbb7f914a1a6953619a8407a93e 194 SUPERFAMILY SSF48452 26 167 3.23E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0021 d23ffdbb7f914a1a6953619a8407a93e 194 Gene3D G3DSA:1.25.40.10 19 113 1.4E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0432 ff5ca3ebf35db3084614e0555a5a1e4b 202 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 2 198 5.9E-60 T 11-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TO73_0432 ff5ca3ebf35db3084614e0555a5a1e4b 202 Pfam PF01914 MarC family integral membrane protein 2 201 4.9E-60 T 11-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TO73_2306 35f0eb896532d22516d717732f2ae071 404 Pfam PF13552 Protein of unknown function (DUF4127) 147 318 6.4E-24 T 11-10-2018 IPR025394 Protein of unknown function DUF4127 TO73_2306 35f0eb896532d22516d717732f2ae071 404 Pfam PF13552 Protein of unknown function (DUF4127) 19 122 2.9E-13 T 11-10-2018 IPR025394 Protein of unknown function DUF4127 TO73_0788 0eb60411f2de968a5f50a8e8914a0932 368 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 9 367 9.0E-100 T 11-10-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 TO73_0788 0eb60411f2de968a5f50a8e8914a0932 368 Pfam PF13439 Glycosyltransferase Family 4 19 178 1.4E-30 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TO73_0788 0eb60411f2de968a5f50a8e8914a0932 368 SUPERFAMILY SSF53756 15 367 3.14E-84 T 11-10-2018 TO73_0788 0eb60411f2de968a5f50a8e8914a0932 368 Gene3D G3DSA:3.40.50.2000 174 350 7.4E-83 T 11-10-2018 TO73_0788 0eb60411f2de968a5f50a8e8914a0932 368 Pfam PF00534 Glycosyl transferases group 1 185 348 1.5E-28 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 TO73_0788 0eb60411f2de968a5f50a8e8914a0932 368 Gene3D G3DSA:3.40.50.2000 19 360 7.4E-83 T 11-10-2018 TO73_1698 cac59ea1f7295c0a663ba8eb10183d5e 457 Pfam PF04293 SpoVR like protein 3 404 7.7E-109 T 11-10-2018 IPR007390 Sporulation stage V, protein R TO73_2373 745ab30e248ac7dfcd538d82f9c7437c 106 Pfam PF11482 Protein of unknown function (DUF3208) 2 106 3.0E-44 T 11-10-2018 IPR021576 Protein of unknown function DUF3208 TO73_2373 745ab30e248ac7dfcd538d82f9c7437c 106 Gene3D G3DSA:3.30.70.2290 1 106 1.1E-49 T 11-10-2018 TO73_1697 6fc6bfb06659628e9961d802cfbffe2e 347 Pfam PF04285 Protein of unknown function (DUF444) 69 151 2.3E-10 T 11-10-2018 IPR006698 Uncharacterised protein family UPF0229 TO73_1697 6fc6bfb06659628e9961d802cfbffe2e 347 Pfam PF04285 Protein of unknown function (DUF444) 159 345 1.2E-49 T 11-10-2018 IPR006698 Uncharacterised protein family UPF0229 TO73_1697 6fc6bfb06659628e9961d802cfbffe2e 347 SUPERFAMILY SSF53300 179 280 1.27E-7 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TO73_2026 25241c48a672d710fec3f735ef7d5b83 183 SUPERFAMILY SSF52980 5 177 4.88E-24 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_2026 25241c48a672d710fec3f735ef7d5b83 183 Gene3D G3DSA:3.90.1570.10 4 181 5.9E-19 T 11-10-2018 TO73_2026 25241c48a672d710fec3f735ef7d5b83 183 Pfam PF05685 Putative restriction endonuclease 12 168 5.2E-30 T 11-10-2018 IPR008538 Domain of unknown function DUF820 TO73_1507 812736046c198f317c372bf74d2c287a 236 Pfam PF12686 Protein of unknown function (DUF3800) 4 215 2.3E-27 T 11-10-2018 IPR024524 Protein of unknown function DUF3800 TO73_2079 9cd1dff5b144d75a369b47e2228a8e23 207 SUPERFAMILY SSF56281 9 198 3.67E-52 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_2079 9cd1dff5b144d75a369b47e2228a8e23 207 Pfam PF00753 Metallo-beta-lactamase superfamily 9 184 1.9E-29 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_2079 9cd1dff5b144d75a369b47e2228a8e23 207 SMART SM00849 12 184 9.9E-36 T 11-10-2018 IPR001279 Metallo-beta-lactamase TO73_2079 9cd1dff5b144d75a369b47e2228a8e23 207 Gene3D G3DSA:3.60.15.10 1 207 8.5E-81 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TO73_2865 df09c2fefad2c2e0658b23eaaea9b988 286 Pfam PF13612 Transposase DDE domain 105 249 3.6E-7 T 11-10-2018 IPR025668 Transposase DDE domain TO73_0942 8b984abfeef454cad882e8f13c13f10b 604 SUPERFAMILY SSF48452 7 57 5.31E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_0942 8b984abfeef454cad882e8f13c13f10b 604 Gene3D G3DSA:1.25.40.10 5 55 7.3E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TO73_1439 c779c2ec6640ee4996602275efb8ec25 359 Pfam PF01098 Cell cycle protein 28 356 7.0E-94 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_1439 c779c2ec6640ee4996602275efb8ec25 359 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 6 359 25.541 T 11-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_1439 c779c2ec6640ee4996602275efb8ec25 359 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 12 356 1.6E-107 T 11-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_1439 c779c2ec6640ee4996602275efb8ec25 359 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 314 338 - T 11-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TO73_0262 3a8634c993ed81cba502a3bffce7c28e 327 SUPERFAMILY SSF48239 33 196 5.65E-7 T 11-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TO73_1972 010410f08034742f6ee2f1542010bb4f 174 Gene3D G3DSA:3.30.420.470 4 169 1.2E-6 T 11-10-2018 TO73_1972 010410f08034742f6ee2f1542010bb4f 174 Pfam PF13358 DDE superfamily endonuclease 3 140 7.5E-18 T 11-10-2018 IPR038717 Tc1-like transposase, DDE domain TO73_2274 ed9bde5eb4d640d9b38e0994afe93b15 338 Pfam PF01757 Acyltransferase family 5 323 1.2E-30 T 11-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TO73_0407 582b1118e4c131fdbc6c55b65ea02b3a 277 Pfam PF00892 EamA-like transporter family 1 133 1.1E-20 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_0407 582b1118e4c131fdbc6c55b65ea02b3a 277 Pfam PF00892 EamA-like transporter family 147 275 7.0E-20 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TO73_0407 582b1118e4c131fdbc6c55b65ea02b3a 277 SUPERFAMILY SSF103481 183 276 5.1E-15 T 11-10-2018 TO73_0407 582b1118e4c131fdbc6c55b65ea02b3a 277 SUPERFAMILY SSF103481 37 138 1.96E-14 T 11-10-2018 TO73_1568 dd7dd91bcc6f93ab38d74093cc836a5c 70 Pfam PF14487 Domain of unknown function (DUF4433) 2 57 4.5E-14 T 11-10-2018 IPR029494 Domain of unknown function DUF4433 TO73_0754 9c12acbf9535c95d69d601bc804c3b65 151 Pfam PF02681 Divergent PAP2 family 6 140 1.2E-49 T 11-10-2018 IPR003832 Protein of unknown function DUF212 TO73_0064 d9f0354d50c27e2d25a3e9e6fc6ceb24 110 Gene3D G3DSA:3.30.70.120 3 110 9.1E-46 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TO73_0064 d9f0354d50c27e2d25a3e9e6fc6ceb24 110 SUPERFAMILY SSF54913 6 105 6.67E-38 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TO73_0064 d9f0354d50c27e2d25a3e9e6fc6ceb24 110 Pfam PF02641 Uncharacterized ACR, COG1993 8 104 1.4E-42 T 11-10-2018 IPR003793 Domain of unknown function DUF190 TO73_1780 b60e9a7b86d223375bdc79a780f56e88 574 SUPERFAMILY SSF52540 131 552 1.74E-12 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_1780 b60e9a7b86d223375bdc79a780f56e88 574 Gene3D G3DSA:3.40.50.300 377 559 1.6E-16 T 11-10-2018 TO73_1304 62c6f09295ce39e4971cf6604db34991 256 Pfam PF03881 Fructosamine kinase 15 253 4.6E-46 T 11-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 TO73_1304 62c6f09295ce39e4971cf6604db34991 256 PIRSF PIRSF006221 6 255 1.7E-43 T 11-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 TO73_1304 62c6f09295ce39e4971cf6604db34991 256 Gene3D G3DSA:3.30.200.20 3 74 1.2E-9 T 11-10-2018 TO73_1304 62c6f09295ce39e4971cf6604db34991 256 SUPERFAMILY SSF56112 12 253 8.6E-39 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily TO73_1304 62c6f09295ce39e4971cf6604db34991 256 Gene3D G3DSA:3.90.1200.10 78 255 1.7E-39 T 11-10-2018 TO73_0022 2d63df422989bd8eb49d3024641b466e 198 Pfam PF03458 UPF0126 domain 7 75 7.1E-19 T 11-10-2018 IPR005115 Uncharacterised domain UPF0126 TO73_0022 2d63df422989bd8eb49d3024641b466e 198 Pfam PF03458 UPF0126 domain 90 165 5.3E-20 T 11-10-2018 IPR005115 Uncharacterised domain UPF0126 TO73_2871 c69fe6c884a336b557901218fe7dee0f 69 Gene3D G3DSA:3.30.160.250 4 64 2.0E-6 T 11-10-2018 TO73_2871 c69fe6c884a336b557901218fe7dee0f 69 SUPERFAMILY SSF143100 4 53 3.27E-10 T 11-10-2018 IPR035069 TTHA1013/TTHA0281-like TO73_0526 38741c56abafc099ee2c007080937110 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 91 111 3.5E-29 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0526 38741c56abafc099ee2c007080937110 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 112 132 3.5E-29 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0526 38741c56abafc099ee2c007080937110 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 36 53 3.5E-29 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0526 38741c56abafc099ee2c007080937110 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 147 173 3.5E-29 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0526 38741c56abafc099ee2c007080937110 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 53 73 3.5E-29 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TO73_0526 38741c56abafc099ee2c007080937110 228 Pfam PF01578 Cytochrome C assembly protein 17 175 3.0E-31 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TO73_2296 e8949c4609077728b178b9626b7dc0dd 121 Pfam PF01934 Protein of unknown function DUF86 15 107 1.5E-26 T 11-10-2018 IPR008201 Protein of unknown function DUF86 TO73_2059 dcfcd1d01ef2fefc1ba75cbc55ef4faf 159 Pfam PF04306 Protein of unknown function (DUF456) 21 155 6.9E-31 T 11-10-2018 IPR007403 Protein of unknown function DUF456 TO73_0650 2b2dd0ea4340bca25ecb5e07e324ea94 462 SUPERFAMILY SSF90257 198 280 1.99E-5 T 11-10-2018 TO73_0650 2b2dd0ea4340bca25ecb5e07e324ea94 462 Pfam PF11283 Protein of unknown function (DUF3084) 4 78 3.6E-23 T 11-10-2018 IPR021435 Protein of unknown function DUF3084 TO73_1915 c4e4f8b21f13b190a5dd8134f5c3d034 627 SUPERFAMILY SSF52980 292 590 1.53E-16 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TO73_1403 856d9cdfda9212442067a7106f7362da 149 Pfam PF05103 DivIVA protein 3 133 1.8E-35 T 11-10-2018 IPR007793 DivIVA family TO73_1403 856d9cdfda9212442067a7106f7362da 149 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 34 3.9E-11 T 11-10-2018 IPR019933 DivIVA domain TO73_1876 3f813d885b9cdff01fb6ea9f27c3060f 77 SUPERFAMILY SSF47598 3 49 3.21E-8 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TO73_1876 3f813d885b9cdff01fb6ea9f27c3060f 77 Pfam PF01402 Ribbon-helix-helix protein, copG family 8 41 7.1E-6 T 11-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TO73_0162 c7a48fa4a984b8cd4c605b7864fe66a8 84 SUPERFAMILY SSF143100 2 71 2.62E-19 T 11-10-2018 IPR035069 TTHA1013/TTHA0281-like TO73_0162 c7a48fa4a984b8cd4c605b7864fe66a8 84 Gene3D G3DSA:3.30.160.250 1 84 2.1E-36 T 11-10-2018 TO73_1576 7430296e4e7275ef407b277fe263f0cb 112 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 16 111 2.4E-31 T 11-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_1576 7430296e4e7275ef407b277fe263f0cb 112 Gene3D G3DSA:1.20.58.1610 1 112 7.4E-41 T 11-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TO73_0368 69e6af2e2c8ea7b5337092c3661b0a21 371 Pfam PF02687 FtsX-like permease family 269 366 1.7E-8 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TO73_0368 69e6af2e2c8ea7b5337092c3661b0a21 371 Pfam PF12704 MacB-like periplasmic core domain 19 213 1.6E-9 T 11-10-2018 IPR025857 MacB-like periplasmic core domain TO73_2822 157d348c68174a165e834bbe28de231f 164 SMART SM00754 28 164 2.1E-12 T 11-10-2018 IPR010895 CHRD TO73_2822 157d348c68174a165e834bbe28de231f 164 Pfam PF07452 CHRD domain 31 162 5.5E-21 T 11-10-2018 IPR010895 CHRD TO73_1111 5abc27ea51c7c2dc0d9066a2ecf91387 227 Pfam PF04298 Putative neutral zinc metallopeptidase 5 218 3.4E-84 T 11-10-2018 IPR007395 Putative neutral zinc metallopeptidase TO73_0246 0b2c67bbee90b9fb873dc6c002064aad 237 Gene3D G3DSA:3.40.50.880 15 235 8.7E-20 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like TO73_1334 7a43173100ca6fc511809f4852d4ba8a 258 Pfam PF06182 ABC-2 family transporter protein 34 257 1.2E-60 T 11-10-2018 IPR010390 Protein of unknown function DUF990 TO73_0719 2c8ab05b2bf1c759d8980e0694f341c9 370 Gene3D G3DSA:3.40.830.10 101 345 1.7E-24 T 11-10-2018 TO73_0719 2c8ab05b2bf1c759d8980e0694f341c9 370 Pfam PF01875 Memo-like protein 105 368 1.2E-51 T 11-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TO73_0719 2c8ab05b2bf1c759d8980e0694f341c9 370 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 103 321 2.1E-19 T 11-10-2018 TO73_1752 d15fc59f0d46aa037176a7d6a628f1fb 285 Gene3D G3DSA:2.60.450.10 64 193 1.4E-7 T 11-10-2018 TO73_1752 d15fc59f0d46aa037176a7d6a628f1fb 285 Pfam PF03968 OstA-like protein 38 139 1.1E-4 T 11-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal TO73_0203 842aaf7bcfdcce9908e8aa4d9852c897 125 SUPERFAMILY SSF160719 14 103 2.22E-10 T 11-10-2018 TO73_2167 c51467013f2bf17f712423e66d86739c 486 Pfam PF09992 Phosphodiester glycosidase 374 483 5.8E-16 T 11-10-2018 IPR018711 Phosphodiester glycosidase TO73_2074 c9788a12e54b0424a7e9a1ef9492f4be 183 Pfam PF14332 Domain of unknown function (DUF4388) 5 107 2.5E-9 T 11-10-2018 IPR025497 Domain of unknown function DUF4388 TO73_0093 8663a61381fb1d7b9501321e32b501b3 75 Gene3D G3DSA:3.30.160.250 3 74 9.5E-16 T 11-10-2018 TO73_0093 8663a61381fb1d7b9501321e32b501b3 75 SUPERFAMILY SSF143100 4 64 4.05E-18 T 11-10-2018 IPR035069 TTHA1013/TTHA0281-like TO73_0093 8663a61381fb1d7b9501321e32b501b3 75 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 14 65 1.1E-7 T 11-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system TO73_0911 3f5743adee8c4636c718a58533dcaffa 356 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 306 2.7E-39 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_0825 c44bc68e14a315a90cb9008479920be9 127 Pfam PF14367 Domain of unknown function (DUF4411) 44 120 2.8E-9 T 11-10-2018 IPR016541 Uncharacterised conserved protein UCP008505 TO73_2253 f6840a65b9205f807628d1d39ba1304e 253 Pfam PF01261 Xylose isomerase-like TIM barrel 19 214 1.6E-17 T 11-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TO73_2253 f6840a65b9205f807628d1d39ba1304e 253 SUPERFAMILY SSF51658 5 234 1.57E-35 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily TO73_2253 f6840a65b9205f807628d1d39ba1304e 253 Gene3D G3DSA:3.20.20.150 4 250 1.5E-43 T 11-10-2018 TO73_1386 caf151a02ac58894e544291814d5a286 461 Pfam PF09670 CRISPR-associated protein (Cas_Cas02710) 62 442 1.2E-84 T 11-10-2018 TO73_1386 caf151a02ac58894e544291814d5a286 461 TIGRFAM TIGR02710 TIGR02710: CRISPR-associated protein, TIGR02710 family 67 429 5.6E-30 T 11-10-2018 IPR014082 CRISPR-associated protein, Cas02710 TO73_1601 5579ffa8e05d58197fcb8663c5df1b25 288 Pfam PF01548 Transposase 27 129 3.4E-22 T 11-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 TO73_1601 5579ffa8e05d58197fcb8663c5df1b25 288 Pfam PF02371 Transposase IS116/IS110/IS902 family 176 254 1.2E-20 T 11-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 TO73_0199 1ba8382cde63c7f00a08107c90033d7c 821 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 160 234 1.5E-13 T 11-10-2018 IPR013491 Caudovirus, tape measure, N-terminal TO73_0709 0e79f4ff610b895f52d3e10c10ab01de 325 Hamap MF_01562 UPF0365 protein . 1 321 47.303 T 11-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity TO73_0709 0e79f4ff610b895f52d3e10c10ab01de 325 Pfam PF12127 SigmaW regulon antibacterial 8 317 2.4E-165 T 11-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity TO73_0679 0ee5fff3a8e3b6ac890a24f3f127057e 219 SUPERFAMILY SSF117070 6 128 3.53E-6 T 11-10-2018 TO73_0765 5bda644dac5b1b445e7319c1b7eb5622 490 Pfam PF04932 O-Antigen ligase 167 316 6.8E-9 T 11-10-2018 IPR007016 O-antigen ligase-related TO73_0826 80f331e6319f01da4a19049f514984d1 393 Pfam PF06114 IrrE N-terminal-like domain 175 305 9.7E-21 T 11-10-2018 IPR010359 IrrE N-terminal-like domain TO73_0826 80f331e6319f01da4a19049f514984d1 393 SMART SM00530 23 78 1.6E-4 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TO73_0826 80f331e6319f01da4a19049f514984d1 393 Gene3D G3DSA:3.40.390.50 177 267 2.0E-5 T 11-10-2018 TO73_0826 80f331e6319f01da4a19049f514984d1 393 SUPERFAMILY SSF47413 22 79 2.73E-6 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TO73_1180 6709a2a530c56dc7a92f4c2073bc3d95 208 Gene3D G3DSA:2.70.70.10 3 163 5.2E-18 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_1180 6709a2a530c56dc7a92f4c2073bc3d95 208 Pfam PF01551 Peptidase family M23 36 136 7.2E-17 T 11-10-2018 IPR016047 Peptidase M23 TO73_1180 6709a2a530c56dc7a92f4c2073bc3d95 208 SUPERFAMILY SSF51261 31 138 9.94E-19 T 11-10-2018 IPR011055 Duplicated hybrid motif TO73_1488 bc5e8d908d4f86fbfbe36040e75334de 246 Pfam PF01925 Sulfite exporter TauE/SafE 3 237 1.7E-46 T 11-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TO73_0639 ebf950768d8d0b767fc9240ab176f4e6 41 Gene3D G3DSA:1.10.490.110 1 39 2.8E-13 T 11-10-2018 TO73_0186 0830e87e51f6838e16de265644b6354d 493 Pfam PF06074 Protein of unknown function (DUF935) 28 483 1.0E-50 T 11-10-2018 IPR009279 Protein of unknown function DUF935 TO73_0621 11a296484394cbe621ae7ea019d7b827 362 Pfam PF00953 Glycosyl transferase family 4 97 248 8.3E-33 T 11-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TO73_0580 ccfabd9915f82db09b3e59479aa79f16 215 Pfam PF04367 Protein of unknown function (DUF502) 61 164 9.1E-25 T 11-10-2018 IPR007462 Protein of unknown function DUF502 TO73_0623 beda10af00f3dee830429c76c5769278 280 Gene3D G3DSA:3.90.1200.10 85 272 9.1E-9 T 11-10-2018 TO73_0623 beda10af00f3dee830429c76c5769278 280 Pfam PF01636 Phosphotransferase enzyme family 34 200 5.0E-9 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase TO73_0623 beda10af00f3dee830429c76c5769278 280 SUPERFAMILY SSF56112 6 248 5.1E-23 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily TO73_1303 60a61ceb59dcd65a0603a8799721558a 247 Pfam PF14332 Domain of unknown function (DUF4388) 2 95 2.7E-14 T 11-10-2018 IPR025497 Domain of unknown function DUF4388 TO73_2017 4a70f67295dbf9f93ff91ea51ed0eec8 113 Pfam PF03780 Asp23 family, cell envelope-related function 2 110 1.8E-23 T 11-10-2018 IPR005531 Alkaline shock protein Asp23 TO73_1008 b8903d56556d564a48bf24a03e90e96f 104 Pfam PF11483 Protein of unknown function (DUF3209) 3 102 2.2E-28 T 11-10-2018 IPR021577 Protein of unknown function DUF3209 TO73_1232 1ce578ab5b532ee406d15769249eb2e1 192 Pfam PF08478 POTRA domain, FtsQ-type 21 88 9.7E-11 T 11-10-2018 IPR013685 POTRA domain, FtsQ-type TO73_1854 1af8dfb6745669294b29e51ffe74e371 212 Gene3D G3DSA:3.40.50.150 11 212 9.0E-59 T 11-10-2018 TO73_1854 1af8dfb6745669294b29e51ffe74e371 212 SUPERFAMILY SSF53335 4 170 5.31E-32 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TO73_1854 1af8dfb6745669294b29e51ffe74e371 212 Pfam PF08241 Methyltransferase domain 42 131 1.1E-20 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TO73_0954 f9015b891fdcca476f2bd5c27b5e8f80 42 Gene3D G3DSA:1.10.10.10 1 42 1.3E-7 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TO73_2766 515a6ecc5c56f1adb43e291b238bbe78 100 Pfam PF04434 SWIM zinc finger 47 78 9.6E-7 T 11-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 TO73_1073 3204cf50a78b6ddb81cac29672c0b669 247 Pfam PF04474 Protein of unknown function (DUF554) 11 240 1.9E-72 T 11-10-2018 IPR007563 Protein of unknown function DUF554 TO73_0560 869823abc0d464f39069e826f335fb29 151 Pfam PF17248 Family of unknown function (DUF5317) 3 115 3.4E-35 T 11-10-2018 IPR035168 Protein of unknown function DUF5317 TO73_0691 cf42d3bce2633f4d129463dc4c649703 77 SUPERFAMILY SSF47598 1 43 3.71E-9 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TO73_0691 cf42d3bce2633f4d129463dc4c649703 77 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 39 1.1E-7 T 11-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TO73_1948 013b07ae7e8cc9110e504a4cac27c1af 139 Pfam PF06146 Phosphate-starvation-inducible E 58 125 3.1E-10 T 11-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like TO73_0977 142eeade5b72e9d1abb1895ef15c2487 372 Pfam PF13808 DDE_Tnp_1-associated 5 86 3.1E-14 T 11-10-2018 IPR032806 H repeat-associated protein, N-terminal TO73_1936 7b4570d5a2a308ba074087b560232d20 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 7.5E-15 T 11-10-2018 IPR032806 H repeat-associated protein, N-terminal TO73_1196 042c1ce0f9f8a519003733d9fa319270 132 Pfam PF12728 Helix-turn-helix domain 17 65 3.9E-9 T 11-10-2018 TO73_0658 45a4c0c255fe88e710ed0d4822b7eba7 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 281 1.0E-33 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_1554 efb67b0dc9e5d6c9df5d4a5d301e38ca 378 Gene3D G3DSA:3.40.50.12780 2 291 4.2E-56 T 11-10-2018 TO73_1554 efb67b0dc9e5d6c9df5d4a5d301e38ca 378 SUPERFAMILY SSF56801 81 325 1.19E-25 T 11-10-2018 TO73_1554 efb67b0dc9e5d6c9df5d4a5d301e38ca 378 Pfam PF00501 AMP-binding enzyme 104 253 3.5E-6 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TO73_2245 449bdf5e335c1136c41bfd9bb66a7060 393 SUPERFAMILY SSF50969 47 389 2.35E-12 T 11-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like TO73_2225 8140d0e635fbbbdcb8d2e30a283c53a1 229 SUPERFAMILY SSF109709 111 179 9.16E-5 T 11-10-2018 TO73_1731 4eb7e41188df8f0f4665e7dc771dc4c6 72 Pfam PF16277 Domain of unknown function (DUF4926) 4 59 1.8E-20 T 11-10-2018 IPR032568 Protein of unknown function DUF4926 TO73_0065 bb9b1c7aea70e80984b4feede4bb7357 202 Gene3D G3DSA:3.90.420.10 12 198 6.6E-51 T 11-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TO73_0065 bb9b1c7aea70e80984b4feede4bb7357 202 Pfam PF00174 Oxidoreductase molybdopterin binding domain 23 166 5.5E-36 T 11-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TO73_0065 bb9b1c7aea70e80984b4feede4bb7357 202 SUPERFAMILY SSF56524 3 184 9.68E-62 T 11-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TO73_0502 a807633c705757eb91224c8843c65fd0 737 SUPERFAMILY SSF52540 5 444 4.82E-12 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TO73_2334 8813dd7c45a3804ae40d18500dfb5411 365 Pfam PF01594 AI-2E family transporter 21 355 1.4E-60 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like TO73_2128 8bce65315727b37c455b2c25688406f2 326 Pfam PF06089 L-asparaginase II 6 318 4.9E-105 T 11-10-2018 IPR010349 L-asparaginase II TO73_0761 1bc675a7f3e5f8e8d7cb73f68a30261f 279 Pfam PF07466 Protein of unknown function (DUF1517) 20 278 1.8E-32 T 11-10-2018 IPR010903 Protein of unknown function DUF1517 TO73_2784 47a5714f44dc024ba41a73b3ab1f0d30 66 SUPERFAMILY SSF57938 4 41 5.36E-5 T 11-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TO73_2287 55c485ed8f9d81d8ee7a102b4e83e657 70 Pfam PF11146 Protein of unknown function (DUF2905) 4 68 5.6E-22 T 11-10-2018 IPR021320 Protein of unknown function DUF2905 TO73_0247 c9c32bbf86e1ea7e61e15a2b28767c8e 166 Pfam PF09988 Uncharacterized metal-binding protein (DUF2227) 2 158 8.5E-41 T 11-10-2018 IPR019250 Protein of unknown function DUF2227, metal-binding TO73_2737 02284201c0bcf790a974decc5f4f42d5 366 SUPERFAMILY SSF46785 58 92 3.9E-6 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TO73_1333 9d13e8faa7e6f7a1d6a4f51f4c13f92c 623 Pfam PF16241 Domain of unknown function (DUF4900) 140 222 9.9E-26 T 11-10-2018 IPR032601 Protein of unknown function DUF4900 TO73_2121 2118a93839229765c5dbae45d166e2e2 66 Gene3D G3DSA:1.20.58.1350 1 66 1.7E-32 T 11-10-2018 IPR038405 Cytochrome oxidase Caa3-type, subunit IV superfamily TO73_1943 53a686eb8e05d2efca0e017d82bc8d99 137 Pfam PF00011 Hsp20/alpha crystallin family 36 135 6.6E-18 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TO73_1943 53a686eb8e05d2efca0e017d82bc8d99 137 Gene3D G3DSA:2.60.40.790 1 136 2.0E-29 T 11-10-2018 IPR008978 HSP20-like chaperone TO73_1943 53a686eb8e05d2efca0e017d82bc8d99 137 SUPERFAMILY SSF49764 21 136 4.45E-31 T 11-10-2018 IPR008978 HSP20-like chaperone TO73_2063 60ba1a6e67c3bb9013f6e3673b4efea9 392 Pfam PF04294 VanW like protein 145 272 1.6E-41 T 11-10-2018 IPR007391 Vancomycin resistance VanW TO73_1540 ef25e1692f3fb1e63f9161a78be0a815 381 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 260 335 5.8E-20 T 11-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TO73_1540 ef25e1692f3fb1e63f9161a78be0a815 381 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 35 113 1.6E-7 T 11-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TO73_0197 6e9859884206eed1e15112f81c3d6c2f 107 Gene3D G3DSA:3.30.2220.10 8 99 2.8E-7 T 11-10-2018 TO73_0751 3dcad61b71253801d93142789c19dfe4 110 Pfam PF03780 Asp23 family, cell envelope-related function 5 102 1.9E-17 T 11-10-2018 IPR005531 Alkaline shock protein Asp23 TO73_1211 19a47cd3aa67e835129092167de0a083 145 Pfam PF07030 Protein of unknown function (DUF1320) 2 126 2.1E-27 T 11-10-2018 IPR009752 Bacteriophage Mu, Gp36 TO73_1079 ed913447a709d23f67e700c288d99c81 453 Pfam PF00654 Voltage gated chloride channel 118 407 9.4E-33 T 11-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TO73_1079 ed913447a709d23f67e700c288d99c81 453 SUPERFAMILY SSF81340 17 408 6.28E-43 T 11-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TO73_1079 ed913447a709d23f67e700c288d99c81 453 Gene3D G3DSA:1.10.3080.10 20 421 7.4E-38 T 11-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TO73_0957 2d0ffcf10230cca5eda1411073f8a6f7 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 6.3E-34 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TO73_1542 5baaf990a9dbe8627564788304ced610 318 Pfam PF12679 ABC-2 family transporter protein 12 315 4.9E-37 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TO73_1740 7fc1b66a3a8719fae234b700f20e2860 213 SUPERFAMILY SSF53098 17 179 6.68E-10 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily TO73_1740 7fc1b66a3a8719fae234b700f20e2860 213 Pfam PF01609 Transposase DDE domain 6 172 4.3E-11 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TO73_1912 bcabd22401144f57ace498b55f892e46 398 Pfam PF03787 RAMP superfamily 38 195 6.1E-15 T 11-10-2018 IPR005537 CRISPR type III-associated RAMP protein TO73_1912 bcabd22401144f57ace498b55f892e46 398 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 40 194 9.4E-18 T 11-10-2018 IPR007522 CRISPR-associated protein TM1795 TO73_0240 da725b3d8830c49b7fb663456111160b 258 Pfam PF02673 Bacitracin resistance protein BacA 6 251 4.1E-71 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TO73_0240 da725b3d8830c49b7fb663456111160b 258 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 256 16.828 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TO73_2267 6dd16a18e7cb7e1bb0359c498cee47b1 248 Pfam PF02535 ZIP Zinc transporter 102 230 1.5E-13 T 11-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 TO73_1786 c7544286371204eb4b6d28314c7c2819 318 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 14 313 1.2E-104 T 11-10-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily TO73_0537 9190269e5d85561dc7eb516d3c6c8943 245 Pfam PF14332 Domain of unknown function (DUF4388) 2 100 1.8E-17 T 11-10-2018 IPR025497 Domain of unknown function DUF4388 TO73_2838 ac198d358107a22fdde7c0e5d868d54a 459 Pfam PF10134 Replication initiator protein A 22 256 3.7E-55 T 11-10-2018 IPR018777 Replication initiator protein A TO73_0787 8485ff93173f81c322ef12c3e5477822 818 Pfam PF02706 Chain length determinant protein 7 74 3.7E-9 T 11-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020