locus-tag	class	description
A0O31_00001	COG0215	cysteine-tRNA ligase activity
A0O31_00002	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A0O31_00005	COG2873	o-acetylhomoserine
A0O31_00006	COG2309	aminopeptidase activity
A0O31_00008	COG0674	pyruvate-flavodoxin oxidoreductase activity
A0O31_00008	COG1013	pyruvate-flavodoxin oxidoreductase activity
A0O31_00008	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A0O31_00008	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A0O31_00011	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A0O31_00011	COG1796	DNA polymerase
A0O31_00012	COG1573	uracil-dna glycosylase
A0O31_00013	COG2197	response regulator
A0O31_00015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0O31_00017	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A0O31_00018	COG2086	electron transfer activity
A0O31_00019	COG1960	acyl-CoA dehydrogenase activity
A0O31_00020	COG5002	protein histidine kinase activity
A0O31_00021	COG0745	RESPONSE REGULATOR receiver
A0O31_00022	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
A0O31_00023	COG3383	formate dehydrogenase (NAD+) activity
A0O31_00025	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A0O31_00028	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A0O31_00029	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A0O31_00031	COG1960	acyl-CoA dehydrogenase activity
A0O31_00033	COG0477	Major facilitator Superfamily
A0O31_00034	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A0O31_00035	COG0183	Belongs to the thiolase family
A0O31_00036	COG1331	Highly conserved protein containing a thioredoxin domain
A0O31_00038	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A0O31_00039	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A0O31_00040	COG2193	ferroxidase activity
A0O31_00041	COG1733	regulation of RNA biosynthetic process
A0O31_00042	COG1980	fructose-bisphosphate aldolase activity
A0O31_00043	COG0800	Aldolase
A0O31_00044	COG1414	Transcriptional regulator
A0O31_00045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A0O31_00047	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A0O31_00052	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_00053	COG2030	dehydratase
A0O31_00053	COG1012	belongs to the aldehyde dehydrogenase family
A0O31_00055	COG3396	Phenylacetate-CoA oxygenase
A0O31_00057	COG3396	Phenylacetate-CoA oxygenase
A0O31_00058	COG1309	transcriptional regulator
A0O31_00063	COG0318	PFAM AMP-dependent synthetase and ligase
A0O31_00067	COG1309	transcriptional regulator
A0O31_00068	COG1960	acyl-CoA dehydrogenase activity
A0O31_00070	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_00071	COG2030	dehydratase
A0O31_00071	COG1012	belongs to the aldehyde dehydrogenase family
A0O31_00073	COG0318	PFAM AMP-dependent synthetase and ligase
A0O31_00074	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_00075	COG4974	Belongs to the 'phage' integrase family
A0O31_00077	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A0O31_00078	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A0O31_00080	COG1802	Transcriptional regulator
A0O31_00082	COG1012	belongs to the aldehyde dehydrogenase family
A0O31_00083	COG0683	leucine binding
A0O31_00084	COG0559	Belongs to the binding-protein-dependent transport system permease family
A0O31_00085	COG0411	ABC transporter
A0O31_00101	COG3181	Tripartite tricarboxylate transporter family receptor
A0O31_00104	COG1063	alcohol dehydrogenase
A0O31_00106	COG0574	Belongs to the PEP-utilizing enzyme family
A0O31_00106	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A0O31_00111	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A0O31_00113	COG0410	ABC transporter
A0O31_00114	COG0411	ABC transporter
A0O31_00118	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0O31_00119	COG2368	4-hydroxyphenylacetate
A0O31_00120	COG1012	belongs to the aldehyde dehydrogenase family
A0O31_00122	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A0O31_00126	COG1136	(ABC) transporter
A0O31_00131	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0O31_00132	COG1307	EDD domain protein, DegV family
A0O31_00133	COG1307	EDD domain protein, DegV family
A0O31_00134	COG1490	D-aminoacyl-tRNA deacylase activity
A0O31_00135	COG3239	Fatty acid desaturase
A0O31_00136	COG0138	bifunctional purine biosynthesis protein purh
A0O31_00138	COG0494	nUDIX hydrolase
A0O31_00143	COG1129	ABC transporter
A0O31_00148	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A0O31_00150	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A0O31_00151	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A0O31_00159	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A0O31_00160	COG0438	transferase activity, transferring glycosyl groups
A0O31_00162	COG1215	transferase activity, transferring glycosyl groups
A0O31_00163	COG1442	glycosyl transferase family 8
A0O31_00163	COG1216	Glycosyl transferase, family 2
A0O31_00165	COG2244	polysaccharide biosynthetic process
A0O31_00173	COG0438	transferase activity, transferring glycosyl groups
A0O31_00174	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A0O31_00176	COG2819	hydrolase of the alpha beta superfamily
A0O31_00177	COG0861	Integral membrane protein TerC family
A0O31_00179	COG2181	nitrate reductase activity
A0O31_00179	COG0247	lactate metabolic process
A0O31_00181	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A0O31_00182	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A0O31_00183	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A0O31_00185	COG0439	Biotin carboxylase
A0O31_00186	COG0511	ligase activity, forming carbon-carbon bonds
A0O31_00187	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A0O31_00191	COG0010	Belongs to the arginase family
A0O31_00194	COG1100	Small GTP-binding protein
A0O31_00196	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A0O31_00197	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A0O31_00200	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A0O31_00203	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A0O31_00205	COG0530	calcium, potassium:sodium antiporter activity
A0O31_00206	COG2239	Acts as a magnesium transporter
A0O31_00210	COG0165	Argininosuccinate lyase
A0O31_00218	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A0O31_00220	COG4221	oxidoreductase activity
A0O31_00221	COG0237	dephospho-CoA kinase activity
A0O31_00223	COG1355	regulation of microtubule-based process
A0O31_00224	COG0557	exoribonuclease II activity
A0O31_00226	COG0824	Thioesterase
A0O31_00227	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A0O31_00229	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A0O31_00236	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A0O31_00238	COG4864	UPF0365 protein
A0O31_00240	COG1702	phosphate starvation-inducible protein PhoH
A0O31_00241	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A0O31_00242	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A0O31_00245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A0O31_00246	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A0O31_00248	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A0O31_00248	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A0O31_00252	COG2304	oxidoreductase activity
A0O31_00253	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0O31_00253	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0O31_00255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A0O31_00255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A0O31_00258	COG0779	Required for maturation of 30S ribosomal subunits
A0O31_00259	COG0195	Participates in both transcription termination and antitermination
A0O31_00261	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A0O31_00263	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A0O31_00263	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A0O31_00264	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_00265	COG1760	l-serine dehydratase
A0O31_00268	COG0335	large ribosomal subunit rRNA binding
A0O31_00269	COG0336	Belongs to the RNA methyltransferase TrmD family
A0O31_00270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A0O31_00272	COG0228	four-way junction DNA binding
A0O31_00274	COG2239	Acts as a magnesium transporter
A0O31_00276	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A0O31_00280	COG1692	metallophosphoesterase
A0O31_00284	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A0O31_00286	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A0O31_00290	COG0183	Belongs to the thiolase family
A0O31_00291	COG1960	acyl-CoA dehydrogenase activity
A0O31_00293	COG0481	GTPase activity
A0O31_00295	COG1760	l-serine dehydratase
A0O31_00297	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A0O31_00308	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A0O31_00309	COG1394	ATPase activity, coupled to movement of substances
A0O31_00310	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
A0O31_00311	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
A0O31_00312	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
A0O31_00313	COG1527	subunit (C
A0O31_00314	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
A0O31_00316	COG1269	ATP hydrolysis coupled proton transport
A0O31_00318	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A0O31_00320	COG2414	aldehyde ferredoxin oxidoreductase
A0O31_00323	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A0O31_00325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0O31_00327	COG0728	peptidoglycan biosynthetic process
A0O31_00330	COG1316	TRANSCRIPTIONal
A0O31_00331	COG1404	Belongs to the peptidase S8 family
A0O31_00333	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A0O31_00337	COG1573	uracil-dna glycosylase
A0O31_00340	COG3842	ATPase activity
A0O31_00343	COG0124	histidyl-tRNA synthetase
A0O31_00344	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A0O31_00345	COG0384	phenazine biosynthesis protein PhzF
A0O31_00346	COG0561	phosphatase activity
A0O31_00347	COG0017	Asparaginyl-tRNA synthetase
A0O31_00348	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A0O31_00349	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A0O31_00350	COG2217	Heavy metal translocating P-type atpase
A0O31_00351	COG0640	Transcriptional regulator
A0O31_00352	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A0O31_00353	COG0739	heme binding
A0O31_00354	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A0O31_00355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A0O31_00357	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A0O31_00358	COG0006	proline dipeptidase activity
A0O31_00359	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A0O31_00360	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A0O31_00362	COG1994	Peptidase M50
A0O31_00370	COG0052	Belongs to the universal ribosomal protein uS2 family
A0O31_00371	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A0O31_00372	COG0528	UMP kinase activity
A0O31_00373	COG0233	cytoplasmic translational termination
A0O31_00374	COG4589	Belongs to the CDS family
A0O31_00375	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A0O31_00376	COG0750	zinc metalloprotease
A0O31_00377	COG1216	Glycosyl transferase, family 2
A0O31_00379	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A0O31_00380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A0O31_00381	COG2359	stage V sporulation protein S
A0O31_00383	COG2137	regulation of response to DNA damage stimulus
A0O31_00387	COG2766	serine protein kinase
A0O31_00389	COG2719	SpoVR family
A0O31_00390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0O31_00393	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0O31_00394	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A0O31_00398	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A0O31_00399	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A0O31_00401	COG2199	diguanylate cyclase activity
A0O31_00404	COG2151	metal-sulfur cluster biosynthetic enzyme
A0O31_00413	COG2181	nitrate reductase activity
A0O31_00416	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A0O31_00419	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0O31_00421	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A0O31_00423	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A0O31_00427	COG2132	Multicopper oxidase
A0O31_00428	COG2832	Protein of unknown function (DUF454)
A0O31_00431	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A0O31_00438	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0O31_00439	COG3191	aminopeptidase activity
A0O31_00442	COG0714	Associated with various cellular activities
A0O31_00445	COG2304	oxidoreductase activity
A0O31_00450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A0O31_00451	COG2884	Cell division ATP-binding protein ftsE
A0O31_00452	COG0793	Belongs to the peptidase S41A family
A0O31_00453	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0O31_00453	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0O31_00454	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A0O31_00455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A0O31_00457	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A0O31_00460	COG0159	tryptophan synthase activity
A0O31_00461	COG0133	tryptophan synthase activity
A0O31_00462	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A0O31_00464	COG1744	ABC transporter substrate-binding protein PnrA-like
A0O31_00470	COG0745	RESPONSE REGULATOR receiver
A0O31_00471	COG0077	Prephenate dehydratase
A0O31_00471	COG1605	Chorismate mutase
A0O31_00472	COG0517	IMP dehydrogenase activity
A0O31_00477	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A0O31_00478	COG2133	pyrroloquinoline quinone binding
A0O31_00479	COG1063	alcohol dehydrogenase
A0O31_00481	COG1254	Belongs to the acylphosphatase family
A0O31_00482	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A0O31_00485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A0O31_00486	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A0O31_00489	COG0183	Belongs to the thiolase family
A0O31_00500	COG0538	isocitrate dehydrogenase activity
A0O31_00501	COG0557	exoribonuclease II activity
A0O31_00508	COG2050	protein possibly involved in aromatic compounds catabolism
A0O31_00510	COG0322	excinuclease ABC activity
A0O31_00512	COG0018	arginyl-trna synthetase
A0O31_00514	COG1428	Deoxynucleoside kinase
A0O31_00515	COG1428	Deoxynucleoside kinase
A0O31_00519	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A0O31_00520	COG0107	imidazoleglycerol-phosphate synthase activity
A0O31_00521	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A0O31_00521	COG0140	phosphoribosyl-ATP diphosphatase activity
A0O31_00522	COG1494	fructose-1,6-bisphosphatase
A0O31_00525	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A0O31_00526	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A0O31_00527	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_00529	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A0O31_00529	COG1213	nucleotidyl transferase
A0O31_00530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A0O31_00531	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A0O31_00533	COG1482	cell wall glycoprotein biosynthetic process
A0O31_00535	COG1515	deoxyribonuclease V activity
A0O31_00537	COG0776	regulation of translation
A0O31_00538	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A0O31_00539	COG0443	Heat shock 70 kDa protein
A0O31_00540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A0O31_00541	COG0484	heat shock protein binding
A0O31_00542	COG0789	Transcriptional regulator
A0O31_00543	COG0542	response to heat
A0O31_00548	COG3118	belongs to the thioredoxin family
A0O31_00552	COG0490	domain, Protein
A0O31_00553	COG0475	glutathione-regulated potassium exporter activity
A0O31_00556	COG0517	IMP dehydrogenase activity
A0O31_00557	COG0475	glutathione-regulated potassium exporter activity
A0O31_00559	COG0305	Participates in initiation and elongation during chromosome replication
A0O31_00560	COG0840	transmembrane signaling receptor activity
A0O31_00561	COG0067	glutamate synthase
A0O31_00561	COG0069	glutamate synthase activity
A0O31_00561	COG0070	glutamate synthase
A0O31_00564	COG0516	GMP reductase activity
A0O31_00564	COG0517	IMP dehydrogenase activity
A0O31_00566	COG0745	RESPONSE REGULATOR receiver
A0O31_00567	COG2205	protein histidine kinase activity
A0O31_00568	COG0704	Plays a role in the regulation of phosphate uptake
A0O31_00570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A0O31_00572	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A0O31_00574	COG0515	serine threonine protein kinase
A0O31_00574	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A0O31_00579	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A0O31_00580	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_00584	COG0717	Belongs to the dCTP deaminase family
A0O31_00588	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A0O31_00589	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0O31_00592	COG0583	DNA-binding transcription factor activity
A0O31_00593	COG3546	catalase activity
A0O31_00594	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A0O31_00594	COG0758	DNA mediated transformation
A0O31_00595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A0O31_00597	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A0O31_00598	COG0372	Belongs to the citrate synthase family
A0O31_00599	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A0O31_00600	COG0616	signal peptide processing
A0O31_00601	COG1714	RDD family
A0O31_00605	COG0235	Class ii aldolase
A0O31_00610	COG4149	molybdate abc transporter
A0O31_00612	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A0O31_00613	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A0O31_00613	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A0O31_00614	COG0083	homoserine kinase activity
A0O31_00616	COG0268	Binds directly to 16S ribosomal RNA
A0O31_00618	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A0O31_00621	COG2010	Cytochrome c
A0O31_00622	COG4235	cytochrome complex assembly
A0O31_00622	COG3088	subunit of a heme lyase
A0O31_00623	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0O31_00624	COG1138	Cytochrome C-type biogenesis protein
A0O31_00625	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
A0O31_00627	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A0O31_00628	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A0O31_00630	COG0785	Cytochrome C biogenesis protein
A0O31_00632	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A0O31_00633	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0O31_00636	COG3258	Cytochrome c
A0O31_00637	COG2010	Cytochrome c
A0O31_00638	COG0737	Belongs to the 5'-nucleotidase family
A0O31_00641	COG3258	Cytochrome c
A0O31_00645	COG2010	Cytochrome c
A0O31_00646	COG3842	ATPase activity
A0O31_00650	COG0504	CTP synthase activity
A0O31_00651	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A0O31_00652	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A0O31_00653	COG0210	DNA helicase
A0O31_00657	COG2205	protein histidine kinase activity
A0O31_00659	COG0515	serine threonine protein kinase
A0O31_00659	COG2815	serine threonine protein kinase
A0O31_00660	COG0631	protein serine/threonine phosphatase activity
A0O31_00663	COG0328	RNA-DNA hybrid ribonuclease activity
A0O31_00664	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0O31_00666	COG0604	alcohol dehydrogenase
A0O31_00680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A0O31_00681	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A0O31_00682	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A0O31_00690	COG0788	formyltetrahydrofolate deformylase activity
A0O31_00691	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A0O31_00692	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A0O31_00693	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A0O31_00695	COG2010	Cytochrome c
A0O31_00697	COG0737	Belongs to the 5'-nucleotidase family
A0O31_00698	COG0174	glutamine synthetase
A0O31_00700	COG0559	Belongs to the binding-protein-dependent transport system permease family
A0O31_00704	COG0747	negative chemotaxis
A0O31_00705	COG0601	transmembrane transport
A0O31_00706	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0O31_00710	COG1132	(ABC) transporter
A0O31_00711	COG1132	(ABC) transporter
A0O31_00715	COG2197	response regulator
A0O31_00716	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A0O31_00717	COG0741	lytic transglycosylase activity
A0O31_00717	COG1196	nuclear chromosome segregation
A0O31_00717	COG0739	heme binding
A0O31_00718	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A0O31_00719	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A0O31_00720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A0O31_00723	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A0O31_00724	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A0O31_00726	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0O31_00727	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A0O31_00728	COG0406	alpha-ribazole phosphatase activity
A0O31_00732	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A0O31_00733	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A0O31_00735	COG0047	phosphoribosylformylglycinamidine synthase activity
A0O31_00737	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A0O31_00740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A0O31_00741	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A0O31_00743	COG0416	fatty acid biosynthetic process
A0O31_00744	COG3118	belongs to the thioredoxin family
A0O31_00745	COG1185	polyribonucleotide nucleotidyltransferase activity
A0O31_00749	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A0O31_00750	COG3706	GGDEF domain
A0O31_00752	COG2154	pterin-4-alpha-carbinolamine dehydratase
A0O31_00753	COG1607	acyl-coa hydrolase
A0O31_00755	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A0O31_00757	COG0483	inositol monophosphate 1-phosphatase activity
A0O31_00758	COG0135	phosphoribosylanthranilate isomerase activity
A0O31_00761	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A0O31_00762	COG1077	Cell shape determining protein MreB Mrl
A0O31_00763	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A0O31_00763	COG1418	mRNA catabolic process
A0O31_00766	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A0O31_00767	COG1058	Belongs to the CinA family
A0O31_00767	COG1546	Belongs to the CinA family
A0O31_00774	COG1175	transmembrane transport
A0O31_00776	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A0O31_00778	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A0O31_00779	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
A0O31_00780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A0O31_00781	COG0714	Associated with various cellular activities
A0O31_00782	COG0574	Belongs to the PEP-utilizing enzyme family
A0O31_00782	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A0O31_00783	COG1272	protein, Hemolysin III
A0O31_00785	COG3850	Histidine kinase
A0O31_00785	COG5002	protein histidine kinase activity
A0O31_00792	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A0O31_00795	COG0546	phosphoglycolate phosphatase activity
A0O31_00803	COG1115	amino acid carrier protein
A0O31_00807	COG1489	DNA binding
A0O31_00814	COG1355	regulation of microtubule-based process
A0O31_00816	COG1011	Hydrolase
A0O31_00818	COG1611	Belongs to the LOG family
A0O31_00819	COG0589	response to stress
A0O31_00820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0O31_00825	COG0302	gtp cyclohydrolase
A0O31_00831	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A0O31_00832	COG0395	ABC-type sugar transport system, permease component
A0O31_00833	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0O31_00836	COG1131	(ABC) transporter
A0O31_00840	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A0O31_00841	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A0O31_00842	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A0O31_00847	COG0606	chelatase, subunit chli
A0O31_00848	COG1803	Methylglyoxal synthase
A0O31_00849	COG1694	Mazg nucleotide pyrophosphohydrolase
A0O31_00851	COG1131	(ABC) transporter
A0O31_00853	COG0477	Major facilitator Superfamily
A0O31_00854	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A0O31_00855	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A0O31_00858	COG1388	LysM domain
A0O31_00858	COG0791	NLP P60 protein
A0O31_00860	COG0445	tRNA wobble uridine modification
A0O31_00866	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A0O31_00866	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0O31_00867	COG1543	Belongs to the glycosyl hydrolase 57 family
A0O31_00868	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A0O31_00869	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A0O31_00870	COG0189	ligase activity
A0O31_00873	COG0066	3-isopropylmalate dehydratase activity
A0O31_00874	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A0O31_00878	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A0O31_00879	COG0492	ferredoxin-NADP+ reductase activity
A0O31_00882	COG0792	nuclease activity
A0O31_00883	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A0O31_00889	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A0O31_00890	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A0O31_00894	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0O31_00896	COG1764	response to oxidative stress
A0O31_00897	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A0O31_00900	COG3842	ATPase activity
A0O31_00901	COG0101	tRNA pseudouridine synthase activity
A0O31_00902	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0O31_00903	COG0601	transmembrane transport
A0O31_00904	COG0747	negative chemotaxis
A0O31_00905	COG0316	Belongs to the HesB IscA family
A0O31_00906	COG0668	transmembrane transport
A0O31_00913	COG2226	methyltransferase
A0O31_00918	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A0O31_00919	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A0O31_00920	COG0022	dehydrogenase e1 component
A0O31_00922	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0O31_00925	COG1476	TRANSCRIPTIONal
A0O31_00934	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A0O31_00935	COG0321	lipoyl(octanoyl) transferase activity
A0O31_00936	COG0300	oxidoreductase activity
A0O31_00938	COG0359	binds to the 23S rRNA
A0O31_00939	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A0O31_00941	COG0360	Binds together with S18 to 16S ribosomal RNA
A0O31_00943	COG0556	nucleotide-excision repair
A0O31_00944	COG0497	DNA recombination
A0O31_00945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A0O31_00954	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A0O31_00955	COG0242	peptide deformylase activity
A0O31_00957	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A0O31_00958	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A0O31_00963	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A0O31_00964	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A0O31_00965	COG0343	queuine tRNA-ribosyltransferase activity
A0O31_00967	COG0628	permease
A0O31_00969	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A0O31_00973	COG1597	lipid kinase activity
A0O31_00976	COG0123	including yeast histone deacetylase and acetoin utilization protein
A0O31_00979	COG2414	aldehyde ferredoxin oxidoreductase
A0O31_00982	COG1902	pentaerythritol trinitrate reductase activity
A0O31_00985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A0O31_00991	COG3956	TIGRFAM MazG family protein
A0O31_00992	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A0O31_00993	COG0693	protein deglycase activity
A0O31_00994	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A0O31_00996	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A0O31_00997	COG1937	Protein conserved in bacteria
A0O31_00999	COG0674	pyruvate-flavodoxin oxidoreductase activity
A0O31_00999	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A0O31_01002	COG0315	cyclic pyranopterin monophosphate synthase activity
A0O31_01011	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A0O31_01014	COG0142	geranyltranstransferase activity
A0O31_01017	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A0O31_01019	COG0297	glycogen (starch) synthase activity
A0O31_01021	COG0745	RESPONSE REGULATOR receiver
A0O31_01023	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A0O31_01024	COG1067	ATP-dependent peptidase activity
A0O31_01027	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A0O31_01030	COG1166	arginine decarboxylase activity
A0O31_01031	COG3706	GGDEF domain
A0O31_01032	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A0O31_01033	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A0O31_01035	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A0O31_01038	COG1175	transmembrane transport
A0O31_01039	COG3833	ABC-type maltose transport systems, permease component
A0O31_01040	COG0366	Alpha amylase catalytic
A0O31_01042	COG1193	negative regulation of DNA recombination
A0O31_01045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A0O31_01046	COG2226	methyltransferase
A0O31_01053	COG0470	DNA polymerase III
A0O31_01059	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A0O31_01067	COG0723	plastoquinol--plastocyanin reductase activity
A0O31_01068	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A0O31_01069	COG0539	negative regulation of cytoplasmic translation
A0O31_01070	COG1950	PFAM Membrane protein of
A0O31_01071	COG0517	IMP dehydrogenase activity
A0O31_01071	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A0O31_01075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0O31_01082	COG1653	transport
A0O31_01088	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A0O31_01090	COG0004	ammonium transporteR
A0O31_01091	COG0347	Belongs to the P(II) protein family
A0O31_01092	COG1420	regulation of RNA biosynthetic process
A0O31_01093	COG0314	molybdopterin synthase activity
A0O31_01095	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A0O31_01096	COG1960	acyl-CoA dehydrogenase activity
A0O31_01098	COG0495	leucyl-tRNA aminoacylation
A0O31_01101	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A0O31_01102	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A0O31_01107	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A0O31_01107	COG1845	cytochrome c oxidase, subunit III
A0O31_01109	COG0109	protoheme IX farnesyltransferase activity
A0O31_01109	COG1612	heme a metabolic process
A0O31_01112	COG0166	Belongs to the GPI family
A0O31_01113	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0O31_01114	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A0O31_01115	COG0459	protein refolding
A0O31_01120	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A0O31_01121	COG2860	membrane
A0O31_01126	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A0O31_01127	COG1278	Cold shock
A0O31_01128	COG1047	Peptidyl-prolyl cis-trans
A0O31_01129	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A0O31_01132	COG0842	Transport permease protein
A0O31_01133	COG1131	(ABC) transporter
A0O31_01135	COG1842	Phage shock protein A
A0O31_01137	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A0O31_01138	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0O31_01141	COG2010	Cytochrome c
A0O31_01142	COG0469	pyruvate kinase activity
A0O31_01143	COG0148	phosphopyruvate hydratase activity
A0O31_01145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A0O31_01146	COG0445	tRNA wobble uridine modification
A0O31_01147	COG0357	Ribosomal RNA small subunit methyltransferase G
A0O31_01148	COG1192	Involved in chromosome partitioning
A0O31_01149	COG1475	DNA binding
A0O31_01150	COG2333	competence protein COMEC
A0O31_01150	COG0658	competence protein
A0O31_01154	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A0O31_01156	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A0O31_01157	COG0205	6-phosphofructokinase activity
A0O31_01159	COG0072	phenylalanine-tRNA ligase activity
A0O31_01159	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0O31_01160	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A0O31_01164	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A0O31_01167	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A0O31_01168	COG1660	Displays ATPase and GTPase activities
A0O31_01173	COG1668	transmembrane transport
A0O31_01174	COG1131	(ABC) transporter
A0O31_01176	COG2096	Adenosyltransferase
A0O31_01180	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A0O31_01181	COG2814	Major facilitator Superfamily
A0O31_01182	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A0O31_01183	COG0581	inorganic phosphate transmembrane transporter activity
A0O31_01184	COG0573	inorganic phosphate transmembrane transporter activity
A0O31_01185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A0O31_01186	COG0482	sulfurtransferase activity
A0O31_01188	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A0O31_01189	COG0735	belongs to the Fur family
A0O31_01194	COG0583	DNA-binding transcription factor activity
A0O31_01195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A0O31_01196	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0O31_01197	COG0181	hydroxymethylbilane synthase activity
A0O31_01199	COG0285	dihydrofolate synthase activity
A0O31_01200	COG0436	Aminotransferase
A0O31_01201	COG0521	Mo-molybdopterin cofactor biosynthetic process
A0O31_01210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A0O31_01211	COG0154	amidase activity
A0O31_01212	COG0301	tRNA thio-modification
A0O31_01214	COG0243	molybdopterin cofactor binding
A0O31_01215	COG2272	Belongs to the type-B carboxylesterase lipase family
A0O31_01216	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A0O31_01218	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
A0O31_01222	COG0477	Major facilitator Superfamily
A0O31_01225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A0O31_01227	COG0105	UTP biosynthetic process
A0O31_01228	COG0631	protein serine/threonine phosphatase activity
A0O31_01229	COG1160	GTP binding
A0O31_01232	COG0736	holo-[acyl-carrier-protein] synthase activity
A0O31_01233	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A0O31_01233	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A0O31_01234	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A0O31_01235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A0O31_01236	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A0O31_01237	COG1450	Type ii and iii secretion system protein
A0O31_01242	COG0473	3-isopropylmalate dehydrogenase activity
A0O31_01244	COG3437	response regulator, receiver
A0O31_01244	COG0784	Response regulator, receiver
A0O31_01248	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A0O31_01250	COG0860	N-Acetylmuramoyl-L-alanine amidase
A0O31_01251	COG0515	serine threonine protein kinase
A0O31_01251	COG2815	serine threonine protein kinase
A0O31_01252	COG1752	Esterase of the alpha-beta hydrolase superfamily
A0O31_01255	COG1139	Iron-sulfur cluster binding protein
A0O31_01257	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A0O31_01262	COG2205	protein histidine kinase activity
A0O31_01263	COG0745	RESPONSE REGULATOR receiver
A0O31_01269	COG2146	nitrite reductase [NAD(P)H] activity
A0O31_01270	COG0719	Fe-S assembly protein
A0O31_01271	COG0719	Fe-S assembly protein
A0O31_01272	COG0396	ATPase activity
A0O31_01275	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0O31_01276	COG4181	ATPase activity
A0O31_01277	COG1136	(ABC) transporter
A0O31_01277	COG0577	efflux transmembrane transporter activity
A0O31_01279	COG0277	FAD linked oxidase domain protein
A0O31_01281	COG0667	Aldo Keto reductase
A0O31_01288	COG0745	RESPONSE REGULATOR receiver
A0O31_01293	COG1136	(ABC) transporter
A0O31_01296	COG0632	four-way junction helicase activity
A0O31_01297	COG1024	Enoyl-CoA hydratase
A0O31_01299	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0O31_01301	COG0137	argininosuccinate synthase activity
A0O31_01302	COG0165	Argininosuccinate lyase
A0O31_01303	COG0165	Argininosuccinate lyase
A0O31_01303	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A0O31_01304	COG0505	Belongs to the CarA family
A0O31_01305	COG2759	Belongs to the formate--tetrahydrofolate ligase family
A0O31_01309	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A0O31_01310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A0O31_01311	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A0O31_01312	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A0O31_01315	COG0799	negative regulation of ribosome biogenesis
A0O31_01317	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A0O31_01322	COG0739	heme binding
A0O31_01324	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A0O31_01325	COG0825	malonyl-CoA metabolic process
A0O31_01329	COG2217	Heavy metal translocating P-type atpase
A0O31_01330	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A0O31_01332	COG1278	Cold shock
A0O31_01333	COG0484	heat shock protein binding
A0O31_01334	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A0O31_01335	COG1968	undecaprenyl-diphosphatase activity
A0O31_01336	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A0O31_01341	COG1309	transcriptional regulator
A0O31_01353	COG1252	NADH dehydrogenase
A0O31_01355	COG1993	acr, cog1993
A0O31_01356	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A0O31_01358	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A0O31_01360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A0O31_01361	COG1335	isochorismatase
A0O31_01362	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A0O31_01363	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A0O31_01369	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A0O31_01370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A0O31_01371	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A0O31_01372	COG0250	Participates in transcription elongation, termination and antitermination
A0O31_01373	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A0O31_01374	COG0081	regulation of translation
A0O31_01375	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A0O31_01376	COG0222	ribosome binding
A0O31_01377	COG0163	prenyltransferase activity
A0O31_01378	COG1960	acyl-CoA dehydrogenase activity
A0O31_01379	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_01380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A0O31_01381	COG1187	pseudouridine synthase activity
A0O31_01383	COG1459	type II secretion system
A0O31_01390	COG4968	Prepilin-type N-terminal cleavage methylation domain
A0O31_01392	COG4968	Prepilin-type N-terminal cleavage methylation domain
A0O31_01393	COG2720	vancomycin resistance protein
A0O31_01395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A0O31_01396	COG0427	acetyl-CoA hydrolase
A0O31_01397	COG0686	Belongs to the AlaDH PNT family
A0O31_01400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A0O31_01401	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A0O31_01402	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A0O31_01403	COG0805	protein transport
A0O31_01404	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A0O31_01404	COG1605	Chorismate mutase
A0O31_01421	COG1643	Atp-dependent helicase
A0O31_01422	COG0187	DNA topoisomerase II activity
A0O31_01425	COG0156	8-amino-7-oxononanoate synthase activity
A0O31_01430	COG0506	proline dehydrogenase activity
A0O31_01431	COG1012	belongs to the aldehyde dehydrogenase family
A0O31_01434	COG0512	Glutamine amidotransferase of anthranilate synthase
A0O31_01435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A0O31_01436	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A0O31_01440	COG1187	pseudouridine synthase activity
A0O31_01441	COG1024	Enoyl-CoA hydratase
A0O31_01442	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A0O31_01443	COG0686	Belongs to the AlaDH PNT family
A0O31_01445	COG1461	Dihydroxyacetone kinase
A0O31_01451	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A0O31_01452	COG0049	tRNA binding
A0O31_01453	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A0O31_01454	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A0O31_01455	COG0051	transcription antitermination factor activity, RNA binding
A0O31_01456	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A0O31_01457	COG0088	Forms part of the polypeptide exit tunnel
A0O31_01458	COG0089	rRNA binding
A0O31_01459	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A0O31_01460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A0O31_01461	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A0O31_01462	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A0O31_01463	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A0O31_01464	COG0255	Belongs to the universal ribosomal protein uL29 family
A0O31_01471	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A0O31_01472	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A0O31_01473	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A0O31_01474	COG1841	ribosomal large subunit assembly
A0O31_01475	COG0200	Binds to the 23S rRNA
A0O31_01476	COG0201	protein transport
A0O31_01477	COG0563	adenylate kinase activity
A0O31_01479	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A0O31_01480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A0O31_01481	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A0O31_01482	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A0O31_01483	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A0O31_01485	COG0203	ribosomal protein L17
A0O31_01495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A0O31_01496	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A0O31_01502	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A0O31_01504	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
A0O31_01505	COG2385	sporulation resulting in formation of a cellular spore
A0O31_01506	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A0O31_01508	COG0194	GDP metabolic process
A0O31_01510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A0O31_01511	COG1438	arginine binding
A0O31_01512	COG2095	MarC family integral membrane protein
A0O31_01514	COG0497	DNA recombination
A0O31_01516	COG1404	Belongs to the peptidase S8 family
A0O31_01517	COG0284	orotidine-5'-phosphate decarboxylase activity
A0O31_01518	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A0O31_01524	COG0822	iron-sulfur transferase activity
A0O31_01525	COG2205	protein histidine kinase activity
A0O31_01529	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0O31_01530	COG1324	tolerance protein
A0O31_01531	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A0O31_01532	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A0O31_01533	COG0537	adenosine 5'-monophosphoramidase activity
A0O31_01536	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A0O31_01539	COG1011	Hydrolase
A0O31_01540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A0O31_01545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A0O31_01546	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A0O31_01547	COG4946	Tricorn protease homolog
A0O31_01547	COG1506	peptidase
A0O31_01547	COG0823	Involved in the tonB-independent uptake of proteins
A0O31_01552	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A0O31_01553	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A0O31_01554	COG0113	porphobilinogen synthase activity
A0O31_01556	COG4274	PFAM GYD family protein
A0O31_01557	COG0519	Catalyzes the synthesis of GMP from XMP
A0O31_01557	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A0O31_01560	COG1854	S-ribosylhomocysteine lyase activity
A0O31_01561	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A0O31_01562	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A0O31_01563	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A0O31_01564	COG0193	aminoacyl-tRNA hydrolase activity
A0O31_01565	COG1181	Belongs to the D-alanine--D-alanine ligase family
A0O31_01567	COG2211	Major facilitator Superfamily
A0O31_01569	COG1349	DNA-binding transcription factor activity
A0O31_01570	COG1653	transport
A0O31_01572	COG0395	ABC-type sugar transport system, permease component
A0O31_01574	COG3345	alpha-galactosidase
A0O31_01575	COG1085	galactose-1-phosphate uridylyltransferase
A0O31_01577	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A0O31_01581	COG2255	four-way junction helicase activity
A0O31_01582	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A0O31_01586	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0O31_01587	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A0O31_01589	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A0O31_01591	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A0O31_01592	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A0O31_01596	COG1007	ATP synthesis coupled electron transport
A0O31_01597	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0O31_01598	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A0O31_01599	COG0713	ATP synthesis coupled electron transport
A0O31_01600	COG0839	Belongs to the complex I subunit 6 family
A0O31_01601	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0O31_01602	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A0O31_01603	COG1034	ATP synthesis coupled electron transport
A0O31_01604	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A0O31_01605	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A0O31_01606	COG0649	NAD binding
A0O31_01607	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0O31_01608	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0O31_01609	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0O31_01610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A0O31_01612	COG4712	double-strand break repair protein
A0O31_01615	COG0582	viral genome integration into host DNA
A0O31_01617	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A0O31_01627	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
A0O31_01635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A0O31_01662	COG0778	Nitroreductase
A0O31_01663	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A0O31_01664	COG0131	Imidazoleglycerol-phosphate dehydratase
A0O31_01665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A0O31_01666	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A0O31_01666	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A0O31_01667	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A0O31_01673	COG0861	Integral membrane protein TerC family
A0O31_01674	COG2151	metal-sulfur cluster biosynthetic enzyme
A0O31_01675	COG0281	malic enzyme
A0O31_01678	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A0O31_01679	COG0509	glycine decarboxylation via glycine cleavage system
A0O31_01680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A0O31_01681	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A0O31_01685	COG0243	molybdopterin cofactor binding
A0O31_01687	COG2197	response regulator
A0O31_01689	COG0196	riboflavin kinase activity
A0O31_01690	COG0494	nUDIX hydrolase
A0O31_01695	COG2813	Specifically methylates the guanine in position
A0O31_01698	COG0039	L-malate dehydrogenase activity
A0O31_01699	COG0358	DNA primase activity
A0O31_01704	COG1205	dead DEAH box helicase
A0O31_01704	COG1111	helicase
A0O31_01705	COG0393	Putative heavy-metal-binding
A0O31_01706	COG0454	-acetyltransferase
A0O31_01706	COG0456	acetyltransferase
A0O31_01708	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A0O31_01715	COG0277	FAD linked oxidase domain protein
A0O31_01716	COG3706	GGDEF domain
A0O31_01717	COG0287	Prephenate dehydrogenase
A0O31_01718	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A0O31_01719	COG2514	catechol 2,3-dioxygenase activity
A0O31_01721	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A0O31_01722	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A0O31_01725	COG1609	Transcriptional regulator
A0O31_01726	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A0O31_01727	COG0179	Fumarylacetoacetate (FAA) hydrolase
A0O31_01729	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A0O31_01730	COG0151	Belongs to the GarS family
A0O31_01731	COG2176	DNA-directed DNA polymerase activity
A0O31_01732	COG0745	RESPONSE REGULATOR receiver
A0O31_01733	COG0784	Response regulator, receiver
A0O31_01733	COG2198	Histidine kinase
A0O31_01733	COG2205	protein histidine kinase activity
A0O31_01735	COG0516	GMP reductase activity
A0O31_01735	COG0517	IMP dehydrogenase activity
A0O31_01737	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0O31_01743	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0O31_01747	COG1733	regulation of RNA biosynthetic process
A0O31_01748	COG2894	cell division
A0O31_01749	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
A0O31_01750	COG0772	Belongs to the SEDS family
A0O31_01751	COG3842	ATPase activity
A0O31_01752	COG1176	ABC-type spermidine putrescine transport system, permease component I
A0O31_01753	COG1177	transmembrane transport
A0O31_01755	COG2010	Cytochrome c
A0O31_01756	COG0129	dihydroxy-acid dehydratase activity
A0O31_01757	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_01760	COG0066	3-isopropylmalate dehydratase activity
A0O31_01761	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A0O31_01762	COG0544	peptidyl-prolyl cis-trans isomerase activity
A0O31_01763	COG0180	Tryptophanyl-tRNA synthetase
A0O31_01765	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A0O31_01769	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0O31_01772	COG2890	protein-(glutamine-N5) methyltransferase activity
A0O31_01775	COG0706	membrane insertase activity
A0O31_01776	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A0O31_01780	COG0318	PFAM AMP-dependent synthetase and ligase
A0O31_01785	COG1121	(ABC) transporter
A0O31_01786	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A0O31_01787	COG1959	2 iron, 2 sulfur cluster binding
A0O31_01788	COG1104	cysteine desulfurase activity
A0O31_01789	COG0318	PFAM AMP-dependent synthetase and ligase
A0O31_01795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A0O31_01796	COG2009	succinate dehydrogenase
A0O31_01799	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A0O31_01800	COG0017	Asparaginyl-tRNA synthetase
A0O31_01803	COG0084	hydrolase, TatD family'
A0O31_01807	COG1175	transmembrane transport
A0O31_01808	COG0395	ABC-type sugar transport system, permease component
A0O31_01816	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A0O31_01818	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A0O31_01821	COG0513	Belongs to the DEAD box helicase family
A0O31_01822	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0O31_01823	COG2046	Belongs to the sulfate adenylyltransferase family
A0O31_01824	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A0O31_01824	COG1648	precorrin-2 dehydrogenase activity
A0O31_01825	COG0730	response to heat
A0O31_01826	COG0175	sulfate reduction
A0O31_01827	COG1648	precorrin-2 dehydrogenase activity
A0O31_01827	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A0O31_01828	COG1587	Uroporphyrinogen-III synthase
A0O31_01829	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0O31_01831	COG0352	thiamine-phosphate diphosphorylase activity
A0O31_01832	COG2104	thiamine diphosphate biosynthetic process
A0O31_01833	COG2022	thiamine diphosphate biosynthetic process
A0O31_01835	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A0O31_01836	COG0351	phosphomethylpyrimidine kinase
A0O31_01836	COG0352	thiamine-phosphate diphosphorylase activity
A0O31_01841	COG4983	Phage plasmid primase, P4 family domain protein
A0O31_01849	COG0582	viral genome integration into host DNA
A0O31_01851	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A0O31_01853	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A0O31_01856	COG5002	protein histidine kinase activity
A0O31_01857	COG0745	RESPONSE REGULATOR receiver
A0O31_01861	COG2070	2-Nitropropane dioxygenase
A0O31_01862	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0O31_01862	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A0O31_01865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A0O31_01866	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A0O31_01867	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0O31_01867	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0O31_01873	COG0492	ferredoxin-NADP+ reductase activity
A0O31_01874	COG1063	alcohol dehydrogenase
A0O31_01876	COG0747	negative chemotaxis
A0O31_01877	COG0601	transmembrane transport
A0O31_01878	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0O31_01879	COG0444	Belongs to the ABC transporter superfamily
A0O31_01881	COG0517	IMP dehydrogenase activity
A0O31_01882	COG0123	including yeast histone deacetylase and acetoin utilization protein
A0O31_01883	COG2104	thiamine diphosphate biosynthetic process
A0O31_01884	COG0037	tRNA processing
A0O31_01886	COG0366	Alpha amylase catalytic
A0O31_01887	COG2226	methyltransferase
A0O31_01891	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A0O31_01892	COG0460	homoserine dehydrogenase
A0O31_01893	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A0O31_01901	COG2050	protein possibly involved in aromatic compounds catabolism
A0O31_01902	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A0O31_01904	COG0247	lactate metabolic process
A0O31_01908	COG0277	FAD linked oxidase domain protein
A0O31_01909	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A0O31_01911	COG0789	Transcriptional regulator
A0O31_01914	COG2045	Belongs to the ComB family
A0O31_01915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0O31_01916	COG1136	(ABC) transporter
A0O31_01917	COG0813	purine-nucleoside phosphorylase activity
A0O31_01918	COG1024	Enoyl-CoA hydratase
A0O31_01921	COG3360	Dodecin
A0O31_01928	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A0O31_01930	COG4974	Belongs to the 'phage' integrase family
A0O31_01933	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A0O31_01936	COG0746	molybdenum cofactor guanylyltransferase activity
A0O31_01937	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A0O31_01939	COG0167	dihydroorotate dehydrogenase activity
A0O31_01940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0O31_01942	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A0O31_01944	COG0730	response to heat
A0O31_01947	COG0312	modulator of DNA gyrase
A0O31_01949	COG1960	acyl-CoA dehydrogenase activity
A0O31_01953	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A0O31_01954	COG0653	protein targeting
A0O31_01955	COG0217	transcriptional regulatory protein
A0O31_01956	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A0O31_01956	COG4651	solute:proton antiporter activity
A0O31_01958	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A0O31_01959	COG1674	ftsk spoiiie
A0O31_01964	COG0419	ATPase involved in DNA repair
A0O31_01968	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A0O31_01969	COG0612	Peptidase, M16
A0O31_01970	COG0612	Peptidase, M16
A0O31_01971	COG0697	spore germination
A0O31_01972	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0O31_01977	COG4956	integral membrane protein (PIN domain superfamily)
A0O31_01978	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A0O31_01979	COG0542	response to heat
A0O31_01980	COG0423	glycine-tRNA ligase activity
A0O31_01981	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A0O31_01985	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0O31_01985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0O31_01986	COG1024	Enoyl-CoA hydratase
A0O31_01987	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A0O31_01988	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A0O31_01989	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A0O31_01991	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A0O31_01992	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A0O31_01993	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A0O31_01995	COG0861	Integral membrane protein TerC family
A0O31_01996	COG0492	ferredoxin-NADP+ reductase activity
A0O31_01997	COG0028	Belongs to the TPP enzyme family
A0O31_01998	COG0440	acetolactate synthase activity
A0O31_01999	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A0O31_02001	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A0O31_02004	COG4555	ABC transporter
A0O31_02006	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A0O31_02008	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A0O31_02010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A0O31_02011	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A0O31_02015	COG2322	membrane
A0O31_02017	COG0768	penicillin binding
A0O31_02020	COG0424	maF-like protein
A0O31_02022	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A0O31_02026	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A0O31_02028	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A0O31_02031	COG2313	pseudouridylate synthase activity
A0O31_02034	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A0O31_02035	COG0569	domain protein
A0O31_02036	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A0O31_02037	COG0058	SHG alpha-glucan phosphorylase activity
A0O31_02042	COG1126	abc transporter atp-binding protein
A0O31_02045	COG3311	Transcriptional regulator
A0O31_02047	COG0134	indole-3-glycerol-phosphate synthase activity
A0O31_02048	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A0O31_02053	COG0525	valine-tRNA ligase activity
A0O31_02055	COG0489	protein tyrosine kinase activity
A0O31_02057	COG2264	protein methyltransferase activity
A0O31_02058	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A0O31_02067	COG1940	carbohydrate kinase activity
A0O31_02070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0O31_02071	COG1120	ATPase activity
A0O31_02073	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_02075	COG1321	iron dependent repressor
A0O31_02076	COG3706	GGDEF domain
A0O31_02076	COG0745	RESPONSE REGULATOR receiver
A0O31_02080	COG2391	methyltransferase activity
A0O31_02089	COG2197	response regulator
A0O31_02090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A0O31_02096	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A0O31_02097	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A0O31_02098	COG0772	Belongs to the SEDS family
A0O31_02099	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A0O31_02100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A0O31_02102	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A0O31_02103	COG0768	penicillin binding
A0O31_02107	COG2001	Belongs to the MraZ family
A0O31_02113	COG5005	Phage virion morphogenesis
A0O31_02142	COG4383	Mu-like prophage protein gp29
A0O31_02161	COG0254	rRNA binding
A0O31_02162	COG1435	thymidine kinase activity
A0O31_02164	COG0154	amidase activity
A0O31_02169	COG0572	uridine kinase
A0O31_02170	COG3842	ATPase activity
A0O31_02174	COG4475	Protein of unknown function (DUF436)
A0O31_02179	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A0O31_02181	COG3870	Protein conserved in bacteria
A0O31_02182	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A0O31_02186	COG0544	peptidyl-prolyl cis-trans isomerase activity
A0O31_02187	COG0740	serine-type endopeptidase activity
A0O31_02188	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A0O31_02189	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A0O31_02190	COG1410	methionine synthase
A0O31_02190	COG0646	methionine synthase
A0O31_02191	COG2897	thiosulfate sulfurtransferase activity
A0O31_02192	COG2738	Putative neutral zinc metallopeptidase
A0O31_02196	COG1196	nuclear chromosome segregation
A0O31_02199	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A0O31_02201	COG1268	BioY protein
A0O31_02203	COG0126	phosphoglycerate kinase activity
A0O31_02204	COG0149	triose-phosphate isomerase activity
A0O31_02209	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A0O31_02212	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A0O31_02213	COG2873	o-acetylhomoserine
A0O31_02217	COG0742	ribosomal rna small subunit methyltransferase
A0O31_02218	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A0O31_02226	COG0402	S-adenosylhomocysteine deaminase activity
A0O31_02228	COG4948	Mandelate Racemase Muconate Lactonizing
A0O31_02229	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A0O31_02230	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0O31_02231	COG1811	Na channel or pump
A0O31_02232	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0O31_02232	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A0O31_02235	COG1215	transferase activity, transferring glycosyl groups
A0O31_02242	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A0O31_02243	COG1012	belongs to the aldehyde dehydrogenase family
A0O31_02245	COG1063	alcohol dehydrogenase
A0O31_02249	COG0318	PFAM AMP-dependent synthetase and ligase
A0O31_02252	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A0O31_02254	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0O31_02254	COG1024	Enoyl-CoA hydratase
A0O31_02255	COG0183	Belongs to the thiolase family
A0O31_02264	COG1648	precorrin-2 dehydrogenase activity
A0O31_02264	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A0O31_02265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A0O31_02266	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A0O31_02267	COG1492	cobalamin metabolic process
A0O31_02271	COG1233	COG1233 Phytoene dehydrogenase and related
A0O31_02274	COG0702	epimerase
A0O31_02277	COG2353	YceI-like domain
A0O31_02279	COG1475	DNA binding
A0O31_02280	COG1192	Involved in chromosome partitioning
A0O31_02287	COG1337	RAMP superfamily
A0O31_02291	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A0O31_02302	COG1518	maintenance of DNA repeat elements
A0O31_02310	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A0O31_02317	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0O31_02320	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A0O31_02321	COG2342	PFAM TM1410 hypothetical-related protein
A0O31_02332	COG0601	transmembrane transport
A0O31_02333	COG0747	negative chemotaxis
A0O31_02340	COG1012	belongs to the aldehyde dehydrogenase family
A0O31_02342	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A0O31_02347	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
A0O31_02349	COG1175	transmembrane transport
A0O31_02351	COG4213	ABC transporter substrate-binding protein
A0O31_02352	COG4214	carbohydrate transport
A0O31_02353	COG1129	ABC transporter
A0O31_02356	COG1070	Carbohydrate kinase
A0O31_02357	COG0006	proline dipeptidase activity
A0O31_02358	COG0673	inositol 2-dehydrogenase activity
A0O31_02362	COG4558	Periplasmic binding protein
A0O31_02363	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0O31_02364	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A0O31_02366	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A0O31_02369	COG1607	acyl-coa hydrolase
A0O31_02371	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0O31_02373	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A0O31_02375	COG0395	ABC-type sugar transport system, permease component
A0O31_02376	COG1175	transmembrane transport
A0O31_02385	COG1518	maintenance of DNA repeat elements
A0O31_02386	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A0O31_02396	COG0587	DNA-directed DNA polymerase activity
A0O31_02403	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A0O31_02406	COG2002	toxin-antitoxin pair type II binding
A0O31_02419	COG2200	EAL domain
A0O31_02419	COG2199	diguanylate cyclase activity
A0O31_02432	COG2132	Multicopper oxidase
A0O31_02433	COG2217	Heavy metal translocating P-type atpase
A0O31_02454	COG2205	protein histidine kinase activity
A0O31_02455	COG0745	RESPONSE REGULATOR receiver
A0O31_02456	COG2010	Cytochrome c
A0O31_02457	COG1914	H( )-stimulated, divalent metal cation uptake system
A0O31_02466	COG2323	membrane
A0O31_02472	COG0628	permease
A0O31_02475	COG1609	Transcriptional regulator
A0O31_02477	COG1175	transmembrane transport
A0O31_02479	COG2723	6-phospho-beta-galactosidase activity
A0O31_02480	COG4565	transcriptional regulatory protein
A0O31_02481	COG3290	protein histidine kinase activity
A0O31_02482	COG3842	ATPase activity
A0O31_02486	COG0410	ABC transporter
A0O31_02491	COG1028	Short-chain dehydrogenase reductase Sdr
A0O31_02492	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A0O31_02496	COG0588	phosphoglycerate mutase activity
A0O31_02502	COG1857	crispr-associated protein
A0O31_02509	COG1175	transmembrane transport
A0O31_02510	COG0395	ABC-type sugar transport system, permease component
A0O31_02511	COG1692	metallophosphoesterase
A0O31_02513	COG0523	cobalamin synthesis protein
A0O31_02516	COG0803	Belongs to the bacterial solute-binding protein 9 family
A0O31_02518	COG1785	Belongs to the alkaline phosphatase family
A0O31_02519	COG1175	transmembrane transport
A0O31_02520	COG0395	ABC-type sugar transport system, permease component
A0O31_02522	COG1840	ABC-type Fe3 transport system, periplasmic component
A0O31_02527	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A0O31_02529	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0O31_02531	COG1562	ergosterol biosynthetic process
A0O31_02532	COG0415	Belongs to the DNA photolyase family
A0O31_02536	COG0463	Glycosyl transferase, family 2
A0O31_02538	COG1304	FMN binding
A0O31_02546	COG0243	molybdopterin cofactor binding
A0O31_02555	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A0O31_02556	COG0248	Ppx GppA phosphatase
A0O31_02557	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A0O31_02564	COG1797	cobyrinic acid a,c-diamide synthase activity
A0O31_02565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A0O31_02567	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A0O31_02569	COG0588	phosphoglycerate mutase activity