locus-tag	class	description
Theos_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Theos_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Theos_0003	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Theos_0004	ENOG4105CA9	Pyruvate kinase
Theos_0006	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
Theos_0007	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Theos_0009	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Theos_0010	ENOG4105DQU	oxidoreductase, subunit beta
Theos_0011	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Theos_0013	ENOG4105VPX	protein, conserved in bacteria
Theos_0014	ENOG4105C6E	dna polymerase iii
Theos_0016	ENOG4107RRU	Involved in both the arginine and lysine biosynthetic pathways (By similarity)
Theos_0017	ENOG4107R7Y	intracellular protease Pfpi family
Theos_0018	ENOG4105P8F	nudix hydrolase
Theos_0019	ENOG4105DXN	mazG family
Theos_0021	ENOG41080T7	secreted protein
Theos_0022	ENOG4108ZX6	Electron transport protein SCO1 SenC
Theos_0024	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Theos_0026	ENOG4105CTD	carboxy-peptidase
Theos_0027	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Theos_0028	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Theos_0029	ENOG4108RWN	rrna methyltransferase
Theos_0032	ENOG4105C89	phosphohexose isomerase
Theos_0033	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
Theos_0034	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Theos_0035	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
Theos_0036	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Theos_0041	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
Theos_0052	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
Theos_0053	ENOG4105EWK	phytoene
Theos_0054	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Theos_0056	ENOG4105D8X	mechanosensitive ion channel
Theos_0057	ENOG4107T9V	chlorite dismutase
Theos_0062	ENOG4105ETX	regulatoR
Theos_0063	ENOG4106F60	Histidine kinase
Theos_0065	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
Theos_0072	ENOG4105PW4	Sugar fermentation stimulation protein homolog
Theos_0075	ENOG4105BZG	amino acid carrier protein
Theos_0082	ENOG4105CQB	FAD linked oxidase domain protein
Theos_0083	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
Theos_0085	ENOG4108UNV	SUF system FeS assembly protein, NifU family
Theos_0086	ENOG4105C9B	Cysteine desulfurase
Theos_0088	ENOG4107STQ	Multicopper oxidase
Theos_0092	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Theos_0094	ENOG4105BZU	Histidine kinase
Theos_0095	ENOG4105ETX	regulatoR
Theos_0101	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Theos_0102	ENOG4108I0Y	(ABC) transporter
Theos_0106	ENOG41067HZ	cytochrome C, class I
Theos_0108	ENOG4107EUI	c reductase, iron-sulfur
Theos_0109	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Theos_0112	ENOG4105DIW	FeS assembly protein SUFB
Theos_0113	ENOG4105C3K	feS assembly ATPase SufC
Theos_0116	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Theos_0118	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Theos_0120	ENOG4106B0N	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Theos_0125	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Theos_0128	ENOG4105CH7	arginosuccinase
Theos_0129	ENOG4105CH7	arginosuccinase
Theos_0130	ENOG4105CDH	Citrulline--aspartate ligase
Theos_0131	ENOG4107QN2	dihydrolipoyl dehydrogenase
Theos_0132	ENOG4105C7S	Dehydrogenase
Theos_0133	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Theos_0134	ENOG4105CGU	Enoyl-CoA hydratase
Theos_0135	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Theos_0136	ENOG4105PAD	Hydrolase
Theos_0139	ENOG41081QV	Universal stress protein
Theos_0141	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Theos_0143	ENOG4105DKQ	ROK family
Theos_0152	ENOG4105EUJ	GTP cyclohydrolase i
Theos_0153	ENOG4108Z0R	Transferase
Theos_0154	ENOG41062IR	nudix hydrolase
Theos_0155	ENOG4105CI3	gtp-binding protein typa
Theos_0157	ENOG4105D1H	recombination factor protein RarA
Theos_0159	ENOG4105DRS	transport system, permease
Theos_0160	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Theos_0162	ENOG4108W6G	cytochrome C
Theos_0165	ENOG4105CJ1	ABC, transporter
Theos_0168	ENOG4105C7S	Dehydrogenase
Theos_0169	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Theos_0170	ENOG4105ZU5	s-layer protein
Theos_0171	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Theos_0172	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Theos_0173	ENOG4105BZU	Histidine kinase
Theos_0174	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Theos_0177	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
Theos_0178	ENOG4105CEV	competence damage-inducible protein
Theos_0179	ENOG4108784	2'-5' rna ligase
Theos_0180	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Theos_0181	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Theos_0182	ENOG4105DFF	Rod shape-determining protein mreb
Theos_0183	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Theos_0185	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Theos_0186	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Theos_0187	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Theos_0190	ENOG4105DP9	ABC transporter
Theos_0191	ENOG4105D38	putrescine abc transporter
Theos_0192	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Theos_0193	ENOG4105CHW	UPF0052 protein
Theos_0196	ENOG4105CHM	Aminotransferase
Theos_0197	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Theos_0198	ENOG4106633	50S ribosomal protein l28
Theos_0200	ENOG4107WSY	Domain of unknown function DUF20
Theos_0202	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Theos_0205	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Theos_0206	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Theos_0209	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Theos_0211	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
Theos_0212	ENOG4105C8B	TIGR00159 family
Theos_0214	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Theos_0215	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Theos_0221	ENOG4105C3M	thioredoxin reductase
Theos_0225	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Theos_0227	ENOG4107QPV	Serine Threonine protein kinase
Theos_0228	ENOG4105KME	endoribonuclease L-psp
Theos_0232	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Theos_0233	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
Theos_0236	ENOG4105DHP	deoxycytidine triphosphate deaminase
Theos_0238	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Theos_0239	ENOG4107ZZY	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Theos_0240	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
Theos_0241	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Theos_0242	ENOG4105C5Q	Transcriptional regulator
Theos_0243	ENOG4105WEF	catalase
Theos_0245	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Theos_0246	ENOG4108UW5	maltose o-acetyltransferase
Theos_0247	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Theos_0248	ENOG4105CKU	formyltetrahydrofolate synthetase
Theos_0251	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Theos_0254	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Theos_0255	ENOG4105K46	50S ribosomal protein l27
Theos_0256	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Theos_0257	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Theos_0262	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Theos_0263	ENOG4105CZX	twitching motility protein
Theos_0269	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Theos_0270	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Theos_0272	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Theos_0273	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Theos_0274	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Theos_0275	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Theos_0276	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Theos_0277	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Theos_0278	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Theos_0279	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Theos_0280	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Theos_0281	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Theos_0282	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Theos_0283	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Theos_0284	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Theos_0285	ENOG4108CHD	50s ribosomal protein l29
Theos_0287	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Theos_0288	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Theos_0289	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Theos_0293	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Theos_0294	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Theos_0295	ENOG410856V	50S ribosomal protein L30
Theos_0296	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Theos_0297	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Theos_0298	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Theos_0300	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Theos_0301	ENOG41067V7	50S ribosomal protein L36
Theos_0302	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Theos_0303	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Theos_0304	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Theos_0305	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Theos_0306	ENOG4108ZT0	50S ribosomal protein l17
Theos_0314	ENOG4105EAH	synthase
Theos_0315	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Theos_0318	ENOG4105D56	permease protein
Theos_0319	ENOG4105EG2	ABC transporter, permease
Theos_0320	ENOG4107R28	alpha amylase, catalytic region
Theos_0322	ENOG4105C83	adenylosuccinate lyase
Theos_0325	ENOG4105C8V	SAICAR synthetase
Theos_0327	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Theos_0329	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Theos_0332	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Theos_0335	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Theos_0336	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Theos_0344	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Theos_0345	ENOG41080DW	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Theos_0346	ENOG4105D52	delta-aminolevulinic acid dehydratase
Theos_0349	ENOG4108ZF3	Phosphatase
Theos_0350	ENOG4105D9P	serine threonine protein kinase
Theos_0356	ENOG4105C4R	Atp-dependent dna helicase
Theos_0357	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
Theos_0363	ENOG4107YU2	histidine triad (hIT) protein
Theos_0364	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Theos_0366	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Theos_0367	ENOG4105ECY	inositol monophosphatase
Theos_0368	ENOG4108UKM	mov34 mpn pad-1 family protein
Theos_0369	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Theos_0370	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Theos_0371	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Theos_0372	ENOG4108UT2	hemolysin iii
Theos_0374	ENOG41062D9	Histidine kinase
Theos_0380	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Theos_0382	ENOG4108Z8I	decarboxylase
Theos_0386	ENOG4105BZU	Histidine kinase
Theos_0387	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Theos_0388	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Theos_0389	ENOG4108URH	decarboxylase
Theos_0391	ENOG4105C98	muts2 protein
Theos_0392	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
Theos_0395	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Theos_0398	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
Theos_0400	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Theos_0401	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Theos_0402	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Theos_0404	ENOG4107QKW	extracellular solute-binding protein family 1
Theos_0407	ENOG4108Z9K	Osmotically inducible protein
Theos_0409	ENOG4105C5X	domain protein
Theos_0412	ENOG4105C87	Aminotransferase class I and II
Theos_0413	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Theos_0415	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Theos_0416	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Theos_0418	ENOG41073R8	VanW family
Theos_0419	ENOG4105I08	Pseudouridine synthase
Theos_0421	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
Theos_0422	ENOG4105C3M	thioredoxin reductase
Theos_0424	ENOG410850P	UPF0102 protein
Theos_0425	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Theos_0426	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Theos_0430	ENOG41084ZW	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Theos_0431	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Theos_0432	ENOG4105D49	3-dehydroquinate synthase
Theos_0433	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Theos_0434	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Theos_0440	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Theos_0442	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Theos_0447	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Theos_0450	ENOG4105D9P	serine threonine protein kinase
Theos_0451	ENOG4105D78	K07001 NTE family protein
Theos_0452	ENOG4105C3F	Signal peptidase i
Theos_0454	ENOG4107QR9	Iron-sulfur cluster binding protein
Theos_0455	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Theos_0461	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Theos_0464	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Theos_0467	ENOG4105ER6	polysaccharide biosynthesis protein
Theos_0469	ENOG4108MKI	Glycosyl transferase, family 2
Theos_0470	ENOG4107RGC	Glycosyl transferase, family 2
Theos_0472	ENOG4108TJN	glycosyl transferase group 1
Theos_0473	ENOG4105E2K	Glycosyl transferase (Group 1
Theos_0479	ENOG4105D3Q	Sugar transferase
Theos_0481	ENOG4105BZU	Histidine kinase
Theos_0485	ENOG4108W63	CRP FNR family transcriptional regulator
Theos_0487	ENOG4105VF7	tolerance protein
Theos_0488	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Theos_0490	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Theos_0491	ENOG4105DR5	peptidase
Theos_0492	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Theos_0493	ENOG4105WH1	Two component transcriptional regulator luxr family
Theos_0496	ENOG4105K70	DNA-binding protein
Theos_0498	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Theos_0500	ENOG4105DG6	mannose-6-phosphate isomerase
Theos_0501	ENOG4105D06	uba thif-type nad fad binding protein
Theos_0502	ENOG4105BZN	citrate synthase
Theos_0503	ENOG4105BZ1	(ABC) transporter
Theos_0504	ENOG4105BZ1	(ABC) transporter
Theos_0507	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Theos_0508	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Theos_0509	ENOG4105DEF	Extracellular solute-binding protein, family 5
Theos_0510	ENOG4108IV0	ABC, transporter
Theos_0511	ENOG4105C0Z	ABC transporter
Theos_0512	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Theos_0513	ENOG4105C32	Amino acid ABC transporter (Permease)
Theos_0515	ENOG4105C5F	glutamine synthetase
Theos_0516	ENOG4105CGH	5'-nucleotidase
Theos_0518	ENOG41067HZ	cytochrome C, class I
Theos_0520	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Theos_0521	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Theos_0522	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
Theos_0523	ENOG4105CIY	formyltetrahydrofolate deformylase
Theos_0524	ENOG4105C0H	protease
Theos_0527	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Theos_0530	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Theos_0531	ENOG4105ESV	Glycosyl transferase, family 4
Theos_0532	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Theos_0536	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Theos_0539	ENOG41080QG	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Theos_0547	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Theos_0549	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Theos_0551	ENOG4105CD3	dihydroorotase
Theos_0554	ENOG4105CXT	aspartate transcarbamylase
Theos_0555	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Theos_0558	ENOG4105C5I	Dehydrogenase
Theos_0561	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Theos_0562	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Theos_0564	ENOG4105C1G	acyl-Coa dehydrogenase
Theos_0565	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
Theos_0567	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Theos_0568	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Theos_0573	ENOG4105CQB	FAD linked oxidase domain protein
Theos_0574	ENOG4105BZU	Histidine kinase
Theos_0576	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Theos_0579	ENOG4108XHF	Pfam:DUF178
Theos_0580	ENOG4105DVY	radical SAM domain protein
Theos_0584	ENOG41071YG	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Theos_0585	ENOG4105ERH	Fumarylacetoacetate hydrolase
Theos_0587	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Theos_0588	ENOG4107QNG	Phosphoribosylglycinamide synthetase
Theos_0589	ENOG4108IRC	dna polymerase iii
Theos_0590	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Theos_0591	ENOG4105BZU	Histidine kinase
Theos_0595	ENOG4107QN1	sodium solute
Theos_0597	ENOG4105CDY	transcriptional regulatory protein
Theos_0598	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Theos_0599	ENOG4107ZQN	disulfide bond
Theos_0600	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Theos_0602	ENOG4105CNU	cell division protein FtsK
Theos_0605	ENOG4105W87	Cbs domain
Theos_0606	ENOG4105CQC	Prephenate dehydratase
Theos_0613	ENOG4108JQ9	ABC transporter
Theos_0614	ENOG4105DIH	basic membrane
Theos_0615	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Theos_0616	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Theos_0617	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Theos_0618	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Theos_0619	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Theos_0621	ENOG4108JPW	Aminotransferase
Theos_0622	ENOG4107VIJ	nudix hydrolase
Theos_0626	ENOG4105D82	Glutamate dehydrogenase
Theos_0627	ENOG4105D82	Glutamate dehydrogenase
Theos_0633	ENOG4105E63	Pfam:DUF178
Theos_0635	ENOG41074B2	UPF0747 protein
Theos_0636	ENOG4105JFG	SpoIID LytB domain protein
Theos_0637	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Theos_0639	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Theos_0640	ENOG41079SJ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Theos_0641	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Theos_0642	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Theos_0643	ENOG41081FY	multiple antibiotic resistance (MarC)-related
Theos_0644	ENOG4107QX3	carboxylase
Theos_0645	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Theos_0651	ENOG41067KJ	GYD family
Theos_0652	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Theos_0653	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
Theos_0654	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Theos_0655	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Theos_0656	ENOG4107UH2	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Theos_0657	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Theos_0658	ENOG4105CPF	Cell wall formation (By similarity)
Theos_0662	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Theos_0663	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Theos_0664	ENOG4105C34	Pseudouridine synthase
Theos_0667	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Theos_0668	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Theos_0669	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Theos_0670	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Theos_0671	ENOG4105CHR	reductase
Theos_0672	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Theos_0673	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Theos_0674	ENOG41067VY	50S ribosomal protein L32
Theos_0678	ENOG4105VQU	rdd domain containing protein
Theos_0679	ENOG4105D07	Signal peptide peptidase, SppA
Theos_0680	ENOG4105DR4	Methyltransferase
Theos_0681	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Theos_0682	ENOG4105CFG	Acts as a chaperone (By similarity)
Theos_0683	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Theos_0684	ENOG4105DVC	DnaJ domain protein
Theos_0685	ENOG4108FYC	transcriptional regulator MERR family
Theos_0686	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Theos_0695	ENOG4105NCW	Trka-c domain protein
Theos_0696	ENOG4107S91	Sodium hydrogen exchanger
Theos_0699	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Theos_0702	ENOG4105CDU	Replicative dna helicase
Theos_0703	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Theos_0704	ENOG4107WFQ	NADH-quinone oxidoreductase, chain M
Theos_0705	ENOG4105D65	subunit l
Theos_0706	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Theos_0707	ENOG41087XN	oxidoreductase
Theos_0708	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Theos_0709	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Theos_0710	ENOG4108IEH	NADH dehydrogenase subunit g
Theos_0711	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
Theos_0712	ENOG4105GKE	subunit e
Theos_0713	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Theos_0714	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Theos_0715	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Theos_0716	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Theos_0717	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Theos_0719	ENOG4105VIZ	double-strand break repair protein
Theos_0727	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Theos_0728	ENOG4108TVJ	Nitroreductase
Theos_0729	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Theos_0730	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Theos_0731	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Theos_0732	ENOG4107Y7Q	pfkb domain protein
Theos_0733	ENOG4105DZS	Phenylacetate-CoA ligase
Theos_0734	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Theos_0735	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Theos_0739	ENOG4107TS3	membrane protein, TerC
Theos_0740	ENOG4105VG1	fes assembly suf system protein
Theos_0741	ENOG4107R1I	NAD-dependent malic enzyme
Theos_0744	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Theos_0745	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Theos_0746	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Theos_0747	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Theos_0748	ENOG4105WZW	rhodanese family
Theos_0750	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Theos_0751	ENOG4107QY8	reductase
Theos_0753	ENOG4105WH1	Two component transcriptional regulator luxr family
Theos_0754	ENOG4105BZU	Histidine kinase
Theos_0755	ENOG4105DTN	riboflavin biosynthesis protein ribF
Theos_0756	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Theos_0758	ENOG4105EFZ	amidohydrolase
Theos_0760	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Theos_0761	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
Theos_0762	ENOG4105CFH	Aspartokinase
Theos_0763	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
Theos_0764	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Theos_0765	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Theos_0766	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Theos_0767	ENOG4105CTP	PilT protein domain protein
Theos_0768	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Theos_0770	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
Theos_0775	ENOG4105CX6	glutaminyL-tRNA synthetase
Theos_0776	ENOG4105E39	Enoyl-CoA hydratase
Theos_0777	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Theos_0778	ENOG410868C	50s ribosomal protein l35
Theos_0779	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Theos_0781	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Theos_0782	ENOG41080X4	futalosine nucleosidase
Theos_0783	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Theos_0784	ENOG4105C9Q	fumarate hydratase class II
Theos_0788	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Theos_0789	ENOG4105DFA	alanine racemase domain protein
Theos_0793	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Theos_0794	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Theos_0796	ENOG4105CPQ	Dehydrogenase
Theos_0797	ENOG4105D8V	Glucose sorbosone dehydrogenase
Theos_0799	ENOG4105E7W	lamb ycsf family protein
Theos_0800	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Theos_0806	ENOG4105EYH	Exonuclease
Theos_0808	ENOG4105CJR	Integral membrane protein (MviN
Theos_0809	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Theos_0810	ENOG4108V5V	Serine Threonine protein kinase
Theos_0811	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Theos_0814	ENOG4105DR4	Methyltransferase
Theos_0816	ENOG4105EBX	v-type atpase
Theos_0819	ENOG41089ID	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Theos_0820	ENOG410704R	Produces ATP from ADP in the presence of a proton gradient across the membrane
Theos_0821	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
Theos_0822	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
Theos_0823	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Theos_0828	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
Theos_0830	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
Theos_0837	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Theos_0838	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
Theos_0839	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
Theos_0842	ENOG4105CDA	abc transporter atp-binding protein
Theos_0851	ENOG4105C2J	ABC transporter
Theos_0852	ENOG4105UIB	(ABC) transporter
Theos_0856	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Theos_0857	ENOG4105E66	phosphoriboisomerase A
Theos_0858	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Theos_0860	ENOG4105CN1	protease
Theos_0861	ENOG4105CAK	Cell division ATP-binding protein ftsE
Theos_0862	ENOG4105MS2	ribosomal subunit Interface protein
Theos_0866	ENOG41082J7	Rhodanese domain protein
Theos_0869	ENOG41082J7	Rhodanese domain protein
Theos_0870	ENOG4107ZT5	Thiol disulfide interchange protein
Theos_0871	ENOG4105ED1	spovr family
Theos_0873	ENOG4105CYN	Serine protein kinase
Theos_0882	ENOG4105D48	metallophosphoesterase
Theos_0883	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Theos_0884	ENOG4105E2X	shikimate dehydrogenase
Theos_0888	ENOG4105C2M	dna polymerase I
Theos_0894	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Theos_0896	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Theos_0897	ENOG41065RQ	ADP-ribosylation crystallin J1
Theos_0898	ENOG4105CJW	magnesium transporter
Theos_0899	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Theos_0900	ENOG4105K5M	30s ribosomal protein S16
Theos_0902	ENOG4106GF2	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Theos_0903	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Theos_0904	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Theos_0905	ENOG4105WH1	Two component transcriptional regulator luxr family
Theos_0906	ENOG4105EJQ	L-serine dehydratase
Theos_0907	ENOG4105KHC	sulfurtransferase
Theos_0910	ENOG4105D3R	alkyl hydroperoxide reductase
Theos_0912	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Theos_0915	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Theos_0917	ENOG4107ZYJ	bioY protein
Theos_0919	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Theos_0920	ENOG4105BZA	Phosphoglycerate kinase
Theos_0923	ENOG4105C8Y	Acetylornithine aminotransferase
Theos_0924	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Theos_0925	ENOG41081CK	Memo-like protein
Theos_0926	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Theos_0927	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Theos_0933	ENOG41060M0	Crispr-associated protein, cse4 family
Theos_0937	ENOG4105PWE	CRISPR-associated protein cas2
Theos_0940	ENOG4106H78	methyltransferase
Theos_0941	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Theos_0942	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Theos_0943	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Theos_0944	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Theos_0949	ENOG4107RUY	(E1 component), alpha subunit
Theos_0950	ENOG4105CHM	Aminotransferase
Theos_0953	ENOG4105CP7	Triose-phosphate isomerase
Theos_0954	ENOG4105ECK	Fatty Acid Desaturase
Theos_0955	ENOG4108M8H	domain protein
Theos_0956	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Theos_0957	ENOG4105EPR	degv family
Theos_0958	ENOG4105EPR	degv family
Theos_0966	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Theos_0969	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Theos_0971	ENOG4105C26	Dehydrogenase
Theos_0972	ENOG4105EFA	4-hydroxyphenylacetate
Theos_0973	ENOG4105MXW	flavin reductase domain protein, FMN-binding
Theos_0977	ENOG4105C0Z	ABC transporter
Theos_0978	ENOG4108IV0	ABC, transporter
Theos_0979	ENOG4107YAU	phenylacetic acid degradation protein
Theos_0980	ENOG4105DZS	Phenylacetate-CoA ligase
Theos_0983	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Theos_0984	ENOG4105P4J	Allophanate hydrolase, subunit 1
Theos_0990	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
Theos_0994	ENOG4105DXM	phenylacetic acid degradation protein
Theos_0995	ENOG4107VFR	oxidoreductase
Theos_1003	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Theos_1004	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
Theos_1005	ENOG4105CH5	extracellular solute-binding protein, family 7
Theos_1008	ENOG4105C7Z	Conserved Protein
Theos_1009	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Theos_1011	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Theos_1013	ENOG4108UQY	Iron-storage protein
Theos_1016	ENOG4107NFR	Fructose-1,6-bisphosphatase
Theos_1017	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Theos_1018	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
Theos_1020	ENOG4108I5C	dEAD DEAH box helicase
Theos_1021	ENOG4105ZU5	s-layer protein
Theos_1024	ENOG4105CSU	acyl-Coa dehydrogenase
Theos_1025	ENOG4105BZU	Histidine kinase
Theos_1026	ENOG4105BZU	Histidine kinase
Theos_1027	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Theos_1028	ENOG4105VG1	fes assembly suf system protein
Theos_1032	ENOG4108Z4U	Ferredoxin
Theos_1040	ENOG4108IUE	nitrate reductase beta subunit
Theos_1044	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Theos_1046	ENOG4105CE1	Ferrous iron transport protein b
Theos_1053	ENOG4105CEI	nitrite reductase
Theos_1054	ENOG4105WD1	Membrane
Theos_1056	ENOG4105DSQ	Nitric oxide reductase
Theos_1057	ENOG4108VKQ	nitriC oxide reductase
Theos_1064	ENOG4105KXX	peptidase s58 dmpa
Theos_1067	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Theos_1070	ENOG4107QVM	von Willebrand factor, type A
Theos_1072	ENOG4105EMU	Dehydrogenase
Theos_1074	ENOG4108IQK	o-acetylhomoserine
Theos_1075	ENOG4105DWV	Homoserine O-trans-acetylase
Theos_1078	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Theos_1082	ENOG4105CHR	reductase
Theos_1085	ENOG4105EHG	Permease protein
Theos_1087	ENOG4105E2R	ROK family
Theos_1098	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Theos_1100	ENOG4105D1F	ATP-binding protein
Theos_1108	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Theos_1109	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Theos_1110	ENOG4105BZU	Histidine kinase
Theos_1111	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Theos_1118	ENOG4108V6E	Cell division protein mraZ
Theos_1119	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Theos_1122	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
Theos_1124	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Theos_1125	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Theos_1126	ENOG4105CNI	cell division protein FtsW
Theos_1127	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Theos_1128	ENOG4105DFU	Cell wall formation (By similarity)
Theos_1129	ENOG4107QWW	Cell wall formation (By similarity)
Theos_1131	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Theos_1133	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Theos_1140	ENOG41066VF	YeeE YedE family protein
Theos_1141	ENOG4105CMR	udp-glucose 4-epimerase
Theos_1143	ENOG41090K0	Transcriptional regulator, Crp Fnr family
Theos_1145	ENOG4105FE1	phytoene synthase
Theos_1146	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Theos_1151	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
Theos_1152	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Theos_1153	ENOG41080IJ	Diacylglycerol kinase
Theos_1155	ENOG4105RTX	GreA GreB family elongation factor
Theos_1156	ENOG4105CRK	lysyL-tRNA synthetase
Theos_1162	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
Theos_1164	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Theos_1165	ENOG4108R6K	riboflavin synthase, subunit alpha
Theos_1167	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Theos_1168	ENOG410836C	Required for maturation of 30S ribosomal subunits (By similarity)
Theos_1169	ENOG4105CHV	Transcription elongation factor NusA
Theos_1170	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Theos_1172	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Theos_1173	ENOG410846T	CoA-transferase family III
Theos_1175	ENOG4105CHU	acetyl-coa acetyltransferase
Theos_1176	ENOG4105C1G	acyl-Coa dehydrogenase
Theos_1178	ENOG4105D78	K07001 NTE family protein
Theos_1179	ENOG4105VT3	DNA binding domain protein, excisionase family
Theos_1181	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Theos_1182	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Theos_1184	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Theos_1186	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Theos_1187	ENOG4105E5Q	amino acid AbC transporter
Theos_1188	ENOG4105EAB	amino acid AbC transporter
Theos_1190	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Theos_1191	ENOG4105C1A	potassium transporter peripheral membrane
Theos_1192	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Theos_1194	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
Theos_1197	ENOG4105KJF	protein tyrosine phosphatase
Theos_1198	ENOG4105ENE	Histidine kinase
Theos_1199	ENOG4106FVC	RNA methyltransferase
Theos_1200	ENOG4105BZ4	penicillin-binding protein
Theos_1203	ENOG4105C3G	gtp-binding protein
Theos_1204	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Theos_1206	ENOG4108Z03	MAF-like protein
Theos_1209	ENOG4105CJN	penicillin-binding protein
Theos_1217	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Theos_1218	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Theos_1220	ENOG4105DBV	ornithine carbamoyltransferase
Theos_1222	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Theos_1224	ENOG4108IUW	ABC transporter
Theos_1227	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Theos_1228	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Theos_1229	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Theos_1231	ENOG4105C7K	acetolactate synthase
Theos_1232	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
Theos_1233	ENOG4105EE5	Membrane protein terC
Theos_1240	ENOG4108VAU	general secretion pathway protein G
Theos_1247	ENOG4105C31	Tryptophanyl-tRNA synthetase
Theos_1249	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Theos_1250	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Theos_1251	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Theos_1254	ENOG4105CHR	reductase
Theos_1255	ENOG4105C01	Dihydroxy-acid dehydratase
Theos_1256	ENOG41067HZ	cytochrome C, class I
Theos_1257	ENOG4107RUE	extracellular solute-binding protein family 1
Theos_1258	ENOG4105D38	putrescine abc transporter
Theos_1259	ENOG4105F38	ABC transporter, permease
Theos_1260	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Theos_1261	ENOG4105CNI	cell division protein FtsW
Theos_1262	ENOG4108CHF	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Theos_1268	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Theos_1269	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Theos_1270	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Theos_1271	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Theos_1272	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Theos_1276	ENOG4108I5C	dEAD DEAH box helicase
Theos_1279	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Theos_1280	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
Theos_1281	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Theos_1282	ENOG4107Y9U	Membrane
Theos_1283	ENOG4105C1V	Peptidase, M16
Theos_1284	ENOG4105C1V	Peptidase, M16
Theos_1289	ENOG4108W6C	Dehydrogenase
Theos_1292	ENOG4105CMG	Carbohydrate kinase
Theos_1295	ENOG4105C2J	ABC transporter
Theos_1296	ENOG4107RNG	ABC transporter
Theos_1297	ENOG4105DFW	ABC transporter
Theos_1302	ENOG4105VTR	Integrase
Theos_1312	ENOG4105VTR	Integrase
Theos_1322	ENOG4105CEC	DNA methylase N-4 N-6
Theos_1326	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
Theos_1328	ENOG4105CE9	30S ribosomal protein S2
Theos_1329	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Theos_1330	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Theos_1331	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Theos_1332	ENOG4105KNE	Phosphatidate cytidylyltransferase
Theos_1333	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Theos_1337	ENOG4105II7	pyrroline-5-carboxylate reductase
Theos_1338	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Theos_1339	ENOG4105MCT	stage V sporulation protein S
Theos_1340	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Theos_1342	ENOG4105CRQ	synthase (Component I)
Theos_1344	ENOG4105C3R	Methionine synthase
Theos_1345	ENOG4105DAP	Nicotinate phosphoribosyltransferase
Theos_1346	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Theos_1347	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Theos_1348	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Theos_1352	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Theos_1353	ENOG4105X0R	protein from nitrogen regulatory protein P-II
Theos_1354	ENOG41066UU	tRNA (Adenine-N1-)-methyltransferase
Theos_1356	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Theos_1360	ENOG4108RZE	Tetr family transcriptional regulator
Theos_1361	ENOG4105C1G	acyl-Coa dehydrogenase
Theos_1362	ENOG4105DXM	phenylacetic acid degradation protein
Theos_1364	ENOG4105CEY	Amp-dependent synthetase and ligase
Theos_1367	ENOG4105EIN	peptidylprolyl cis-trans isomerase
Theos_1368	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Theos_1369	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Theos_1370	ENOG4105C1Q	protoporphyrinogen oxidase
Theos_1372	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Theos_1373	ENOG4108XAN	ABC transporter
Theos_1374	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Theos_1375	ENOG4107QIZ	NADH dehydrogenase
Theos_1377	ENOG4108IEG	Formate dehydrogenase Alpha subunit
Theos_1378	ENOG4105CH5	extracellular solute-binding protein, family 7
Theos_1381	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Theos_1383	ENOG4106IQC	argininosuccinate lyase
Theos_1386	ENOG4108IV0	ABC, transporter
Theos_1387	ENOG4105C0Z	ABC transporter
Theos_1388	ENOG4108IQE	Amp-dependent synthetase and ligase
Theos_1389	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Theos_1390	ENOG4108UIC	UPF0340 protein
Theos_1393	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Theos_1395	ENOG4105DBI	uridine monophosphokinase
Theos_1399	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Theos_1400	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Theos_1401	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Theos_1403	ENOG4107T8J	thymidine kinase
Theos_1404	ENOG41082DI	50s ribosomal protein l31
Theos_1406	ENOG4105DI5	UPF0365 protein
Theos_1408	ENOG4105C9A	Phoh family
Theos_1409	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Theos_1413	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Theos_1424	ENOG4107QM5	aconitate hydratase
Theos_1427	ENOG4108KGH	TRANSCRIPTIONal
Theos_1430	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Theos_1434	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Theos_1435	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Theos_1436	ENOG4105E0C	molybdate abc transporter
Theos_1437	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Theos_1440	ENOG4105CUT	histidyl-tRNA synthetase
Theos_1441	ENOG4105C9M	aspartyl-trna synthetase
Theos_1442	ENOG4107ZY0	Phenazine biosynthesis-like protein
Theos_1444	ENOG4105C5S	asparaginyl-tRNA synthetase
Theos_1445	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Theos_1453	ENOG4105CGD	Nad-dependent epimerase dehydratase
Theos_1462	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Theos_1464	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Theos_1465	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Theos_1466	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Theos_1467	ENOG4105DC7	peptidase M24
Theos_1468	ENOG4107QUV	Domain protein
Theos_1470	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Theos_1471	ENOG4108Z4T	Peptidase M50
Theos_1473	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Theos_1475	ENOG4105CPK	Glycosyl transferase (Group 1
Theos_1476	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Theos_1478	ENOG4108SA1	esterase
Theos_1479	ENOG4107TS3	membrane protein, TerC
Theos_1481	ENOG4105DF6	Fe-S oxidoreductase
Theos_1484	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Theos_1485	ENOG41082MB	Involved in the transcription termination process (By similarity)
Theos_1487	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Theos_1488	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Theos_1489	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Theos_1493	ENOG4105CYW	agmatinase
Theos_1496	ENOG4105CXV	gliding motility protein
Theos_1498	ENOG4105NAA	Cytochrome C oxidase, subunit II
Theos_1499	ENOG4107RQ2	Cytochrome c oxidase, subunit I
Theos_1501	ENOG4105C6X	Major Facilitator
Theos_1502	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Theos_1503	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Theos_1504	ENOG4105CN5	Metallo-Beta-Lactamase
Theos_1507	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Theos_1508	ENOG4105BZU	Histidine kinase
Theos_1509	ENOG4105C1G	acyl-Coa dehydrogenase
Theos_1510	ENOG4105BZJ	Electron transfer flavoprotein
Theos_1511	ENOG4105C10	Electron transfer flavoprotein
Theos_1513	ENOG4108HNZ	carboxyl transferase
Theos_1514	ENOG4105E50	uracil-dna glycosylase
Theos_1515	ENOG4105DCG	PHP domain protein
Theos_1520	ENOG4105C88	aminopeptidase
Theos_1523	ENOG4108FXY	Cys/Met metabolism PLP-dependent enzyme
Theos_1524	ENOG4105DMF	Dehydrogenase
Theos_1525	ENOG4105E1F	short-chain dehydrogenase reductase
Theos_1526	ENOG41068KF	Universal stress protein
Theos_1527	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Theos_1528	ENOG4105C8N	cysteinyl-tRNA synthetase
Theos_1529	ENOG4105C1G	acyl-Coa dehydrogenase
Theos_1530	ENOG4105CHU	acetyl-coa acetyltransferase
Theos_1536	ENOG4105CEY	Amp-dependent synthetase and ligase
Theos_1539	ENOG4105E2A	Dehydrogenase
Theos_1540	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
Theos_1541	ENOG4105C26	Dehydrogenase
Theos_1542	ENOG4108JA2	transcriptioN-repair coupling factor
Theos_1545	ENOG4105CPK	Glycosyl transferase (Group 1
Theos_1547	ENOG4108MKI	Glycosyl transferase, family 2
Theos_1548	ENOG4107V8I	Glycosyl transferases group 1
Theos_1549	ENOG4105K64	Glycosyl transferase, family 2
Theos_1552	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
Theos_1553	ENOG4108UQV	Membrane
Theos_1555	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Theos_1556	ENOG4105DTQ	mandelate racemase muconate lactonizing
Theos_1558	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Theos_1561	ENOG4105KHN	chorismate mutase
Theos_1562	ENOG4105C26	Dehydrogenase
Theos_1563	ENOG41062BK	proline dehydrogenase
Theos_1564	ENOG4107XBN	GntR Family Transcriptional Regulator
Theos_1568	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Theos_1569	ENOG4105XEZ	This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands and protects the DNA from cleavage by the
Theos_1571	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Theos_1572	ENOG4105CQ7	ATP-dependent helicase
Theos_1575	ENOG4105E2A	Dehydrogenase
Theos_1581	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
Theos_1586	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Theos_1587	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Theos_1588	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Theos_1589	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Theos_1590	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Theos_1593	ENOG4105DCF	alanine dehydrogenase
Theos_1594	ENOG4105CYC	Transferase
Theos_1595	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Theos_1596	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Theos_1597	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Theos_1600	ENOG4108AH5	Binds directly to 16S ribosomal RNA (By similarity)
Theos_1602	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Theos_1605	ENOG4108M1T	Cytochrome c-type biogenesis protein
Theos_1606	ENOG4107QX9	Thiol disulfide interChange protein
Theos_1607	ENOG4105DA4	cytochrome c-type biogenesis protein
Theos_1608	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
Theos_1610	ENOG41060IM	Heme exporter protein
Theos_1611	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
Theos_1612	ENOG4105DA5	(ABC) transporter
Theos_1613	ENOG4107QIV	Cytochrome c biogenesis protein
Theos_1615	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
Theos_1616	ENOG4107S7U	Sulfide dehydrogenase
Theos_1619	ENOG4105QN4	diheme cytochrome
Theos_1620	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
Theos_1621	ENOG4105CGH	5'-nucleotidase
Theos_1622	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
Theos_1623	ENOG4105QN4	diheme cytochrome
Theos_1627	ENOG41067HZ	cytochrome C, class I
Theos_1628	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Theos_1632	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Theos_1633	ENOG4105C2C	drug resistance transporter, Bcr CflA
Theos_1634	ENOG4108Z7R	Chaperone CsaA
Theos_1637	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Theos_1640	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Theos_1641	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Theos_1642	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Theos_1643	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Theos_1644	ENOG4105CBT	Fructose-1,6-bisphosphatase
Theos_1649	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
Theos_1654	ENOG4105F8V	Hydrolase, tatD family
Theos_1657	ENOG4105C5S	asparaginyl-tRNA synthetase
Theos_1658	ENOG4105E33	succinate dehydrogenase
Theos_1662	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Theos_1664	ENOG4105CIG	ABC transporter
Theos_1668	ENOG4105CEY	Amp-dependent synthetase and ligase
Theos_1669	ENOG4108UJD	30S ribosomal protein S9
Theos_1670	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Theos_1671	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Theos_1674	ENOG4105CBC	glutamate synthase
Theos_1680	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Theos_1681	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
Theos_1682	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Theos_1684	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Theos_1703	ENOG4108HMX	isocitrate dehydrogenase (NADP)
Theos_1706	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Theos_1710	ENOG4105KA0	thioesterase Superfamily protein
Theos_1711	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Theos_1713	ENOG4105C75	arginyL-tRNA synthetase
Theos_1714	ENOG4105C0H	protease
Theos_1717	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Theos_1720	ENOG4105CBX	hi0933 family
Theos_1723	ENOG4105CKK	Glycosyl transferase, family 2
Theos_1725	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Theos_1726	ENOG4105BZU	Histidine kinase
Theos_1729	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Theos_1733	ENOG4106F1P	AAA ATPase, central domain protein
Theos_1737	ENOG4107RSM	transcriptional regulator
Theos_1742	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
Theos_1744	ENOG4108N5B	2-phosphosulfolactate phosphatase
Theos_1747	ENOG4105C1J	atp-dependent rna helicase
Theos_1748	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Theos_1753	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
Theos_1756	ENOG4105E3H	phosphoglycerate mutase
Theos_1757	ENOG4105SFS	phosphoesterase RecJ domain protein
Theos_1759	ENOG4105CHR	reductase
Theos_1761	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Theos_1762	ENOG4105CAT	Cytidine monophosphate kinase
Theos_1763	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Theos_1764	ENOG4107QI6	Cysteine desulfurase
Theos_1765	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Theos_1766	ENOG41080V6	ABC-3 protein
Theos_1767	ENOG4105DIK	(ABC) transporter
Theos_1768	ENOG4108IV0	ABC, transporter
Theos_1770	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Theos_1771	ENOG4105C32	Amino acid ABC transporter (Permease)
Theos_1772	ENOG4105CEY	Amp-dependent synthetase and ligase
Theos_1773	ENOG4105C0Z	ABC transporter
Theos_1776	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Theos_1777	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Theos_1778	ENOG4105VB6	UPF0109 protein
Theos_1779	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Theos_1781	ENOG4108IUZ	ABC transporter
Theos_1782	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Theos_1784	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Theos_1789	ENOG4105CEY	Amp-dependent synthetase and ligase
Theos_1790	ENOG4105WKW	Pfam:DUF1458
Theos_1793	ENOG4105E39	Enoyl-CoA hydratase
Theos_1794	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
Theos_1795	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Theos_1796	ENOG4105IJJ	transcriptional regulator, crp fnr family
Theos_1797	ENOG4108N5B	2-phosphosulfolactate phosphatase
Theos_1798	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Theos_1799	ENOG4105KNI	merR family transcriptional Regulator
Theos_1800	ENOG4107HP6	Transcriptional regulator
Theos_1801	ENOG4107R9S	Malate synthase
Theos_1803	ENOG4105CQB	FAD linked oxidase domain protein
Theos_1804	ENOG4105EU8	FAD linked oxidase domain protein
Theos_1805	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Theos_1811	ENOG4106YGA	NADH dehydrogenase (quinone)
Theos_1819	ENOG4105D6E	homoserine dehydrogenase
Theos_1820	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Theos_1822	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Theos_1824	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Theos_1825	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Theos_1826	ENOG4105CG3	alpha amylase, catalytic region
Theos_1828	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Theos_1829	ENOG4106C07	ThiamineS Protein
Theos_1830	ENOG4105DGU	Histone deacetylase
Theos_1831	ENOG41080XP	Cbs domain
Theos_1833	ENOG4105C3U	ABC transporter
Theos_1834	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Theos_1836	ENOG4107QRA	Extracellular solute-binding protein, family 5
Theos_1838	ENOG4105CAY	ferredoxin--nadp reductase
Theos_1849	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Theos_1851	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Theos_1853	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Theos_1858	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Theos_1861	ENOG4105C8T	Leucyl-tRNA synthetase
Theos_1862	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Theos_1865	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
Theos_1866	ENOG4108Z5K	methylglyoxal synthase
Theos_1867	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Theos_1872	ENOG4105CPC	Aldo Keto reductase
Theos_1875	ENOG4105DAN	ATP-dependent protease
Theos_1876	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Theos_1878	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Theos_1880	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Theos_1882	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Theos_1883	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Theos_1887	ENOG4105EMK	carboxylate amino acid amine transporter
Theos_1888	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Theos_1898	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Theos_1899	ENOG4107ZT3	family UPF0126
Theos_1900	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Theos_1907	ENOG4105G5W	regulator Fur family
Theos_1908	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Theos_1909	ENOG4105CBJ	Metal-dependent enzyme
Theos_1910	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Theos_1912	ENOG4105C8U	phosphate abc transporter
Theos_1914	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Theos_1916	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Theos_1918	ENOG4105K4H	Nlp p60 protein
Theos_1919	ENOG4108DBC	nitroreductase
Theos_1921	ENOG4105C1G	acyl-Coa dehydrogenase
Theos_1922	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Theos_1924	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Theos_1928	ENOG4105C4K	Nad synthetase
Theos_1930	ENOG4107RFW	hydrolase family 57
Theos_1931	ENOG4107U4Q	acetylglutamate kinase
Theos_1932	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Theos_1933	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Theos_1934	ENOG4106928	lysine biosynthesis protein LysW
Theos_1936	ENOG4108S93	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Theos_1937	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Theos_1940	ENOG4108JZA	Homocitrate synthase
Theos_1941	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Theos_1942	ENOG4105C1G	acyl-Coa dehydrogenase
Theos_1943	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Theos_1944	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Theos_1945	ENOG4108VZM	50s ribosomal protein L10
Theos_1946	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Theos_1947	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Theos_1948	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Theos_1949	ENOG410683Z	Preprotein translocase SecE subunit
Theos_1950	ENOG4105WDJ	50S ribosomal protein L33
Theos_1951	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Theos_1956	ENOG4105CY0	Metallo-Beta-Lactamase
Theos_1957	ENOG4105SYT	Methylenetetrahydrofolate reductase
Theos_1961	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
Theos_1964	ENOG4105KJJ	Uncharacterized ACR, COG1993
Theos_1965	ENOG4105WMR	Protein CrcB homolog
Theos_1966	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Theos_1968	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Theos_1969	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
Theos_1970	ENOG4107QHF	type ii secretion system protein e
Theos_1971	ENOG4105CZX	twitching motility protein
Theos_1972	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Theos_1978	ENOG41087YS	Phage shock protein A
Theos_1982	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Theos_1983	ENOG4105MA4	psp1 domain protein
Theos_1986	ENOG4105UIB	(ABC) transporter
Theos_1987	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Theos_1988	ENOG4108UXE	Protein tyrosine phosphatase
Theos_1991	ENOG4107QYG	anthranilate phosphoribosyltransferase
Theos_1992	ENOG4105DDQ	anthranilate synthase
Theos_1993	ENOG4105CRQ	synthase (Component I)
Theos_1994	ENOG41067HZ	cytochrome C, class I
Theos_1998	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Theos_2002	ENOG4105C22	threonyL-tRNA synthetase
Theos_2007	ENOG4105CBD	Diacylglycerol kinase
Theos_2008	ENOG4105CVJ	phosphoglycerate mutase
Theos_2010	ENOG4105DGU	Histone deacetylase
Theos_2012	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Theos_2013	ENOG4105CB5	ATP-dependent DNA helicase recG
Theos_2014	ENOG4105BZU	Histidine kinase
Theos_2016	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Theos_2017	ENOG4108ZAF	Molybdopterin
Theos_2020	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Theos_2021	ENOG4105C25	Primosomal protein n'
Theos_2023	ENOG41090A4	Pterin carbinolamine dehydratase
Theos_2026	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Theos_2028	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Theos_2030	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Theos_2031	ENOG4106FU4	Archease protein family (MTH1598/TM1083)
Theos_2036	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Theos_2037	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Theos_2041	ENOG4108WBT	adenosyltransferase
Theos_2043	ENOG4108IUW	ABC transporter
Theos_2048	ENOG4105C8Y	Acetylornithine aminotransferase
Theos_2051	ENOG4108KB0	deacetylase
Theos_2052	ENOG4105BZU	Histidine kinase
Theos_2054	ENOG4105CEP	NADH dehydrogenase
Theos_2059	ENOG4107SFQ	iron-sulfur binding
Theos_2062	ENOG4108E87	P-loop hydrolase UPF0079
Theos_2063	ENOG4107QX9	Thiol disulfide interChange protein
Theos_2064	ENOG4105HYT	Uncharacterized metal-binding protein (DUF2227)
Theos_2066	ENOG4107Z3H	Transcriptional regulator, TetR family
Theos_2069	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Theos_2070	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Theos_2071	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Theos_2072	ENOG4105C5R	Aminotransferase
Theos_2073	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Theos_2076	ENOG4108Z4U	Ferredoxin
Theos_2083	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Theos_2089	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Theos_2091	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Theos_2092	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Theos_2095	ENOG4107QN2	dihydrolipoyl dehydrogenase
Theos_2099	ENOG4105CPP	Dehydrogenase, E1 component
Theos_2100	ENOG4107SUU	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Theos_2101	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Theos_2104	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Theos_2108	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Theos_2111	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Theos_2112	ENOG4105FE9	pseudouridine synthase
Theos_2113	ENOG4105E39	Enoyl-CoA hydratase
Theos_2114	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Theos_2115	ENOG4105DCF	alanine dehydrogenase
Theos_2116	ENOG4108ZAA	Alkaline-shock protein
Theos_2117	ENOG4105DP4	dak2 domain fusion protein ylov
Theos_2120	ENOG4105D60	lipoprotein releasing system transmembrane protein
Theos_2121	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Theos_2122	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Theos_2123	ENOG4105Z8H	single-stranded DNA-binding protein
Theos_2124	ENOG41082AW	Binds together with S18 to 16S ribosomal RNA (By similarity)
Theos_2126	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Theos_2127	ENOG4105W8H	transhydrogenase (subunit alpha
Theos_2128	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Theos_2132	ENOG4105C0P	Mg chelatase subunit ChlI
Theos_2133	ENOG4108J2R	molybdopterin oxidoreductase
Theos_2134	ENOG4105EBR	Carboxylesterase
Theos_2135	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Theos_2137	ENOG4105CH5	extracellular solute-binding protein, family 7
Theos_2138	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Theos_2140	ENOG4105C57	major facilitator superfamily
Theos_2142	ENOG4105EEI	dihydropteroate synthase
Theos_2143	ENOG4105KRF	dihydroneopterin aldolase
Theos_2151	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Theos_2156	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Theos_2157	ENOG4108ZF3	Phosphatase
Theos_2158	ENOG4107RSM	transcriptional regulator
Theos_2159	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Theos_2160	ENOG4107QSN	dihydrolipoamide acetyltransferase
Theos_2161	ENOG4107T3P	ABC, transporter
Theos_2167	ENOG4105EU0	Major facilitator Superfamily
Theos_2169	ENOG4105C2X	Arabinose 5-phosphate isomerase
Theos_2170	ENOG41082T9	Membrane
Theos_2171	ENOG4105MKU	Transcriptional regulator
Theos_2172	ENOG4105CJ1	ABC, transporter
Theos_2173	ENOG4107QWP	ABC-2 type transporter
Theos_2176	ENOG4105C6T	cysteine synthase
Theos_2177	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Theos_2178	ENOG4105VEQ	Cold shock protein
Theos_2179	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Theos_2183	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Theos_2184	ENOG4105CHM	Aminotransferase
Theos_2185	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Theos_2186	ENOG4105G5W	regulator Fur family
Theos_2187	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Theos_2188	ENOG4105C0B	DNA polymerase III (alpha subunit)
Theos_2192	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Theos_2193	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Theos_2195	ENOG4105CTQ	phosphohexokinase
Theos_2198	ENOG4105F0N	pyrophosphate phospho-hydrolase
Theos_2202	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Theos_2203	ENOG4105FA0	parb-like partition protein
Theos_2204	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
Theos_2205	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Theos_2206	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Theos_2210	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Theos_2218	ENOG4105C2J	ABC transporter
Theos_2219	ENOG4105FUY	alpha subunit
Theos_2220	ENOG4108SBK	dioxygenase, subunit beta
Theos_2226	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
Theos_2229	ENOG4105JXH	GntR family transcriptional regulator
Theos_2233	ENOG4105C32	Amino acid ABC transporter (Permease)
Theos_2234	ENOG4105C0Z	ABC transporter
Theos_2235	ENOG4108IV0	ABC, transporter
Theos_2265	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Theos_2270	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Theos_2277	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Theos_2287	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
Theos_2289	ENOG4105ETE	Transcriptional regulator (LacI family
Theos_2290	ENOG4105DWF	phosphomethylpyrimidine kinase
Theos_2292	ENOG41079KZ	Major Facilitator Superfamily
Theos_2293	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Theos_2294	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Theos_2295	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Theos_2296	ENOG4108G2S	Thiamine biosynthesis protein thiS
Theos_2297	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Theos_2298	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
Theos_2299	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
Theos_2300	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Theos_2301	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
Theos_2302	ENOG4107TSN	permease
Theos_2303	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Theos_2304	ENOG4107RIQ	Sulfate adenylate transferase
Theos_2306	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Theos_2310	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Theos_2311	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Theos_2312	ENOG4105K8R	UPF0145 protein
Theos_2314	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Theos_2315	ENOG4105D9G	High-affinity
Theos_2316	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Theos_2317	ENOG41081F0	Precorrin-8x methylmutase
Theos_2318	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
Theos_2319	ENOG4105DVK	Precorrin-2 c20-methyltransferase
Theos_2320	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Theos_2321	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Theos_2322	ENOG4108P62	biosynthesis protein (CbiG)
Theos_2325	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Theos_2326	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Theos_2331	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Theos_2333	ENOG4108IV0	ABC, transporter
Theos_2341	ENOG4105G6Z	alkaline phosphatase
Theos_2346	ENOG4105DRS	transport system, permease
Theos_2347	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Theos_2349	ENOG4108S4H	thioesterase Superfamily protein
Theos_2358	ENOG4108MES	Periplasmic binding protein
Theos_2360	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Theos_2361	ENOG4105EHG	Permease protein
Theos_2362	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Theos_2365	ENOG4106F60	Histidine kinase
Theos_2366	ENOG4105ETX	regulatoR
Theos_2372	ENOG4105K6V	RNA polymerase
Theos_2379	ENOG4105DSE	periplasmic solute binding protein
Theos_2381	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Theos_2382	ENOG4105C9X	ppx gppa phosphatase
Theos_2392	ENOG4105DRS	transport system, permease
Theos_2393	ENOG4105D48	metallophosphoesterase
Theos_2396	ENOG4108IJ6	ABC transporter
Theos_2399	ENOG4108UHU	Aldolase
Theos_2400	ENOG4107HP6	Transcriptional regulator
Theos_2402	ENOG4105CHR	reductase
Theos_2404	ENOG4105DG4	malate L-lactate dehydrogenase
Theos_2405	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
Theos_2406	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Theos_2408	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
Theos_2411	ENOG4105D2S	major facilitator superfamily
Theos_2412	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
Theos_2413	ENOG4105FA0	parb-like partition protein
Theos_2414	ENOG4105C0D	helicase
Theos_2428	ENOG4105DEF	Extracellular solute-binding protein, family 5
Theos_2429	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Theos_2430	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Theos_2431	ENOG4108Z86	Glutamine amidotransferase
Theos_2432	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Theos_2433	ENOG4105CE4	GlcNAc 6-P deacetylase
Theos_2440	ENOG4107UWC	ABC, transporter
Theos_2441	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
Theos_2443	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
Theos_2445	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Theos_2448	ENOG4107PP3	Acetylornithine deacetylase
Theos_2450	ENOG4105C26	Dehydrogenase
Theos_2456	ENOG4107TXC	Transcriptional regulator
Theos_2457	ENOG4105DZS	Phenylacetate-CoA ligase
Theos_2458	ENOG4105CHR	reductase
Theos_2460	ENOG4105C32	Amino acid ABC transporter (Permease)
Theos_2462	ENOG4105C0Z	ABC transporter
Theos_2463	ENOG4108IV0	ABC, transporter
Theos_2464	ENOG4107FKK	extracellular solute-binding protein family 1
Theos_2465	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
Theos_2466	ENOG4105DRS	transport system, permease
Theos_2467	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Theos_2472	ENOG41084KP	4-oxalocrotonate tautomerase
Theos_2498	ENOG4108UUM	single-stranded DNA-binding protein
Theos_2545	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Theos_2546	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Theos_2547	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
Theos_2548	ENOG4105FA0	parb-like partition protein
Theos_2551	ENOG4105C0D	helicase
Theos_2551	ENOG4105C0D	helicase
