Theos_1721 93b3a6ea5b872014a0146e46dc95d40c 284 Pfam PF03060 Nitronate monooxygenase 80 233 1.7E-23 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 Theos_1721 93b3a6ea5b872014a0146e46dc95d40c 284 Gene3D G3DSA:3.20.20.70 1 284 5.3E-75 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1721 93b3a6ea5b872014a0146e46dc95d40c 284 SUPERFAMILY SSF51412 1 280 3.51E-54 T 14-10-2018 Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 Gene3D G3DSA:4.10.320.10 143 183 8.8E-19 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 Gene3D G3DSA:3.30.559.10 207 447 3.0E-82 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 SUPERFAMILY SSF51230 1 91 3.14E-25 T 14-10-2018 IPR011053 Single hybrid motif Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 Pfam PF00364 Biotin-requiring enzyme 3 75 8.2E-16 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 Pfam PF02817 e3 binding domain 143 178 9.1E-13 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 SUPERFAMILY SSF52777 208 449 2.71E-82 T 14-10-2018 Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 SUPERFAMILY SSF47005 139 182 1.16E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 220 449 4.0E-84 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Theos_2096 bc770e19f706e7fdce4346065a3de96e 451 Gene3D G3DSA:2.40.50.100 1 97 4.5E-24 T 14-10-2018 Theos_1929 90c5acbb5bb6c4c8c5e79d3f7d360eaf 287 SUPERFAMILY SSF56317 3 267 2.49E-57 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Theos_1929 90c5acbb5bb6c4c8c5e79d3f7d360eaf 287 Pfam PF00795 Carbon-nitrogen hydrolase 5 260 7.2E-32 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Theos_1929 90c5acbb5bb6c4c8c5e79d3f7d360eaf 287 Gene3D G3DSA:3.60.110.10 1 264 7.8E-63 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 Gene3D G3DSA:3.40.50.720 2 86 6.1E-21 T 14-10-2018 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 Gene3D G3DSA:3.40.1190.10 87 299 7.9E-49 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 Pfam PF08245 Mur ligase middle domain 103 281 1.4E-13 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 Pfam PF01225 Mur ligase family, catalytic domain 4 95 4.6E-19 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 444 30.768 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 Pfam PF02875 Mur ligase family, glutamate ligase domain 302 383 1.1E-15 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 SUPERFAMILY SSF51984 1 85 4.05E-19 T 14-10-2018 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 Gene3D G3DSA:3.90.190.20 300 443 8.3E-44 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 SUPERFAMILY SSF53244 301 441 4.88E-35 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 3 440 4.6E-107 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_1128 de11e2ce91ed34467a60bc7bfbdbfb27 444 SUPERFAMILY SSF53623 84 299 8.5E-46 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_1635 086b73f80f56b977f307813c57652173 86 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 68 5.3E-12 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Theos_1635 086b73f80f56b977f307813c57652173 86 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 42 3.6E-11 T 14-10-2018 Theos_1635 086b73f80f56b977f307813c57652173 86 SUPERFAMILY SSF143120 1 43 7.85E-9 T 14-10-2018 IPR036165 YefM-like superfamily Theos_1635 086b73f80f56b977f307813c57652173 86 Gene3D G3DSA:3.40.1620.10 1 39 1.7E-5 T 14-10-2018 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 SUPERFAMILY SSF53706 2 569 4.19E-196 T 14-10-2018 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 Pfam PF00384 Molybdopterin oxidoreductase 54 476 2.2E-89 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 SUPERFAMILY SSF50692 530 677 4.97E-49 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 Gene3D G3DSA:2.40.40.20 557 678 1.3E-42 T 14-10-2018 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 Gene3D G3DSA:3.40.50.740 60 524 2.4E-179 T 14-10-2018 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 Gene3D G3DSA:3.40.228.10 134 332 2.4E-179 T 14-10-2018 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 605 632 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 SMART SM00926 1 51 1.3E-13 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 Pfam PF01568 Molydopterin dinucleotide binding domain 567 670 1.8E-30 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 2 47 1.2E-13 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 3 674 3.6E-232 T 14-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 Theos_1377 9035db28b08fc1a08982c5302c67c8f2 679 Gene3D G3DSA:2.20.25.90 1 49 3.3E-19 T 14-10-2018 Theos_2168 c0c798c82518d129b14bff7a2860e5f0 268 SUPERFAMILY SSF52402 158 268 2.43E-16 T 14-10-2018 Theos_2168 c0c798c82518d129b14bff7a2860e5f0 268 PRINTS PR01438 Universal stress protein signature 246 268 3.5E-6 T 14-10-2018 IPR006015 Universal stress protein A Theos_2168 c0c798c82518d129b14bff7a2860e5f0 268 PRINTS PR01438 Universal stress protein signature 154 172 3.5E-6 T 14-10-2018 IPR006015 Universal stress protein A Theos_2168 c0c798c82518d129b14bff7a2860e5f0 268 Pfam PF00582 Universal stress protein family 2 147 3.2E-18 T 14-10-2018 IPR006016 UspA Theos_2168 c0c798c82518d129b14bff7a2860e5f0 268 SUPERFAMILY SSF52402 1 148 1.67E-22 T 14-10-2018 Theos_2168 c0c798c82518d129b14bff7a2860e5f0 268 Gene3D G3DSA:3.40.50.12370 1 268 5.9E-86 T 14-10-2018 Theos_1200 4989b8770f031af4b2071f044ad59dd6 679 Pfam PF00912 Transglycosylase 68 234 4.0E-52 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1200 4989b8770f031af4b2071f044ad59dd6 679 Gene3D G3DSA:3.40.710.10 280 665 4.4E-111 T 14-10-2018 Theos_1200 4989b8770f031af4b2071f044ad59dd6 679 SUPERFAMILY SSF56601 218 656 1.37E-106 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Theos_1200 4989b8770f031af4b2071f044ad59dd6 679 Gene3D G3DSA:1.10.3810.10 59 251 1.6E-53 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1200 4989b8770f031af4b2071f044ad59dd6 679 Pfam PF00905 Penicillin binding protein transpeptidase domain 345 585 1.3E-27 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Theos_1200 4989b8770f031af4b2071f044ad59dd6 679 SUPERFAMILY SSF53955 44 258 9.84E-56 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SUPERFAMILY SSF55781 182 336 3.05E-25 T 14-10-2018 Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SMART SM00091 334 400 5.7E-10 T 14-10-2018 IPR000014 PAS domain Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Gene3D G3DSA:3.20.20.450 781 1002 8.8E-64 T 14-10-2018 IPR035919 EAL domain superfamily Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Pfam PF13185 GAF domain 20 155 5.2E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Pfam PF13185 GAF domain 180 325 3.8E-21 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Gene3D G3DSA:3.30.450.40 159 334 4.0E-28 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SMART SM00065 180 334 5.0E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SMART SM00065 20 165 0.44 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SUPERFAMILY SSF141868 783 999 4.05E-59 T 14-10-2018 IPR035919 EAL domain superfamily Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Pfam PF00563 EAL domain 783 999 9.0E-53 T 14-10-2018 IPR001633 EAL domain Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SUPERFAMILY SSF55785 339 443 1.19E-22 T 14-10-2018 IPR035965 PAS domain superfamily Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SMART SM00052 775 1002 3.5E-56 T 14-10-2018 IPR001633 EAL domain Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SMART SM00267 606 765 3.8E-4 T 14-10-2018 IPR000160 GGDEF domain Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SUPERFAMILY SSF55781 4 155 1.16E-14 T 14-10-2018 Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 335 446 6.5E-15 T 14-10-2018 IPR000014 PAS domain Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Gene3D G3DSA:3.30.70.270 619 780 3.5E-12 T 14-10-2018 Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Gene3D G3DSA:3.30.450.40 2 158 1.7E-14 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Pfam PF00990 Diguanylate cyclase, GGDEF domain 671 760 3.6E-6 T 14-10-2018 IPR000160 GGDEF domain Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Pfam PF00989 PAS fold 335 441 2.4E-10 T 14-10-2018 IPR013767 PAS fold GO:0006355 Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 Gene3D G3DSA:3.30.450.20 335 468 1.1E-25 T 14-10-2018 Theos_0955 1769c917bac910687900a4b5d42ebfb7 1002 SUPERFAMILY SSF55073 666 761 3.3E-8 T 14-10-2018 IPR029787 Nucleotide cyclase Theos_0625 a63152ec624865b84946e6f63c844775 530 SUPERFAMILY SSF53720 12 501 2.75E-138 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_0625 a63152ec624865b84946e6f63c844775 530 Gene3D G3DSA:3.40.309.10 267 469 2.9E-141 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Theos_0625 a63152ec624865b84946e6f63c844775 530 Gene3D G3DSA:3.40.605.10 25 493 2.9E-141 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_0625 a63152ec624865b84946e6f63c844775 530 Pfam PF00171 Aldehyde dehydrogenase family 29 498 4.9E-135 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Theos_0625 a63152ec624865b84946e6f63c844775 530 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Theos_0743 82fe9dd7a8e034e4ca15ecddf3f17386 576 SUPERFAMILY SSF52540 128 554 1.13E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0743 82fe9dd7a8e034e4ca15ecddf3f17386 576 Gene3D G3DSA:3.40.50.300 379 561 2.2E-16 T 14-10-2018 Theos_1946 a551b0aa7088578ae04e27e417cb4e5c 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 3.4E-100 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Theos_1946 a551b0aa7088578ae04e27e417cb4e5c 229 PIRSF PIRSF002155 1 228 5.3E-85 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_1946 a551b0aa7088578ae04e27e417cb4e5c 229 SUPERFAMILY SSF56808 6 227 3.66E-84 T 14-10-2018 IPR023674 Ribosomal protein L1-like Theos_1946 a551b0aa7088578ae04e27e417cb4e5c 229 Pfam PF00687 Ribosomal protein L1p/L10e family 31 221 8.1E-54 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein Theos_1946 a551b0aa7088578ae04e27e417cb4e5c 229 Gene3D G3DSA:3.40.50.790 68 160 2.5E-88 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich Theos_1946 a551b0aa7088578ae04e27e417cb4e5c 229 Gene3D G3DSA:3.30.190.20 23 225 2.5E-88 T 14-10-2018 Theos_1946 a551b0aa7088578ae04e27e417cb4e5c 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 140 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_1946 a551b0aa7088578ae04e27e417cb4e5c 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.187 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Theos_1341 308b466af9933a250a549e2c971e59d7 243 Gene3D G3DSA:3.20.10.10 98 235 3.2E-27 T 14-10-2018 Theos_1341 308b466af9933a250a549e2c971e59d7 243 SUPERFAMILY SSF56752 17 223 3.53E-40 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 Theos_1341 308b466af9933a250a549e2c971e59d7 243 Gene3D G3DSA:3.30.470.10 1 97 6.6E-18 T 14-10-2018 Theos_1341 308b466af9933a250a549e2c971e59d7 243 Pfam PF01063 Amino-transferase class IV 24 221 1.3E-28 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 Theos_0750 d64a76e42d9fc93c1ad2b3d3ac9fd742 195 Gene3D G3DSA:3.30.70.20 4 178 2.1E-73 T 14-10-2018 Theos_0750 d64a76e42d9fc93c1ad2b3d3ac9fd742 195 Pfam PF13247 4Fe-4S dicluster domain 51 144 9.4E-26 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_0750 d64a76e42d9fc93c1ad2b3d3ac9fd742 195 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_0750 d64a76e42d9fc93c1ad2b3d3ac9fd742 195 SUPERFAMILY SSF54862 1 178 1.57E-70 T 14-10-2018 Theos_0750 d64a76e42d9fc93c1ad2b3d3ac9fd742 195 Gene3D G3DSA:3.30.70.20 64 115 2.1E-73 T 14-10-2018 Theos_1152 fb13d7923588bafd1812ce7f0ac77339 139 Gene3D G3DSA:3.40.390.30 2 139 1.3E-33 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 Theos_1152 fb13d7923588bafd1812ce7f0ac77339 139 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 139 16.436 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Theos_1152 fb13d7923588bafd1812ce7f0ac77339 139 SUPERFAMILY SSF55486 4 138 5.86E-32 T 14-10-2018 Theos_1152 fb13d7923588bafd1812ce7f0ac77339 139 Pfam PF02130 Uncharacterized protein family UPF0054 22 138 4.9E-29 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Theos_1152 fb13d7923588bafd1812ce7f0ac77339 139 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 138 2.0E-25 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Theos_0984 42052017d4df334b4485e5f4f9728c89 505 Gene3D G3DSA:2.40.100.10 383 492 1.0E-32 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Theos_0984 42052017d4df334b4485e5f4f9728c89 505 SMART SM00796 2 188 2.9E-71 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D Theos_0984 42052017d4df334b4485e5f4f9728c89 505 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 244 490 1.2E-58 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B Theos_0984 42052017d4df334b4485e5f4f9728c89 505 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 4 188 2.0E-61 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D Theos_0984 42052017d4df334b4485e5f4f9728c89 505 SUPERFAMILY SSF160467 3 81 8.5E-15 T 14-10-2018 Theos_0984 42052017d4df334b4485e5f4f9728c89 505 Gene3D G3DSA:2.40.100.10 75 207 5.4E-55 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Theos_0984 42052017d4df334b4485e5f4f9728c89 505 SUPERFAMILY SSF50891 77 198 4.55E-39 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Theos_0984 42052017d4df334b4485e5f4f9728c89 505 SMART SM00797 243 504 1.5E-55 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B Theos_0984 42052017d4df334b4485e5f4f9728c89 505 Gene3D G3DSA:3.30.1360.40 1 70 1.1E-24 T 14-10-2018 Theos_0984 42052017d4df334b4485e5f4f9728c89 505 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 5 196 1.1E-46 T 14-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 Theos_0143 b658f1c4d7f97d5794bf239a1c99dd7a 301 SUPERFAMILY SSF53067 1 294 1.7E-63 T 14-10-2018 Theos_0143 b658f1c4d7f97d5794bf239a1c99dd7a 301 Gene3D G3DSA:3.30.420.40 124 277 9.6E-110 T 14-10-2018 Theos_0143 b658f1c4d7f97d5794bf239a1c99dd7a 301 Gene3D G3DSA:3.30.420.40 4 290 9.6E-110 T 14-10-2018 Theos_0143 b658f1c4d7f97d5794bf239a1c99dd7a 301 Pfam PF00480 ROK family 4 292 3.0E-66 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Theos_0143 b658f1c4d7f97d5794bf239a1c99dd7a 301 ProSitePatterns PS01125 ROK family signature. 132 159 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Theos_0295 1c23de70821e5edd7dbb64fd88c08abe 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 17.498 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0295 1c23de70821e5edd7dbb64fd88c08abe 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 57 9.2E-26 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0295 1c23de70821e5edd7dbb64fd88c08abe 60 SUPERFAMILY SSF55129 1 59 1.96E-17 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Theos_0295 1c23de70821e5edd7dbb64fd88c08abe 60 PIRSF PIRSF002211 1 60 2.2E-24 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0295 1c23de70821e5edd7dbb64fd88c08abe 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 53 5.1E-15 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain Theos_0295 1c23de70821e5edd7dbb64fd88c08abe 60 Gene3D G3DSA:3.30.1390.20 1 60 1.6E-23 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Theos_0095 3aab5c924b411b9e882bc2e2f87da53c 225 SMART SM00862 141 217 1.9E-30 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0095 3aab5c924b411b9e882bc2e2f87da53c 225 Gene3D G3DSA:3.40.50.2300 1 121 1.4E-37 T 14-10-2018 Theos_0095 3aab5c924b411b9e882bc2e2f87da53c 225 SUPERFAMILY SSF52172 2 168 2.41E-40 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0095 3aab5c924b411b9e882bc2e2f87da53c 225 Gene3D G3DSA:1.10.10.10 122 222 4.6E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0095 3aab5c924b411b9e882bc2e2f87da53c 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 142 217 2.6E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0095 3aab5c924b411b9e882bc2e2f87da53c 225 Pfam PF00072 Response regulator receiver domain 3 110 2.4E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0095 3aab5c924b411b9e882bc2e2f87da53c 225 SMART SM00448 1 110 2.1E-43 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 Gene3D G3DSA:3.10.20.70 2 109 4.1E-38 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 1.3E-27 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 443 1.8E-167 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 14-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 Gene3D G3DSA:3.30.590.10 110 446 1.9E-140 T 14-10-2018 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 SUPERFAMILY SSF55931 107 443 6.57E-130 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 SUPERFAMILY SSF54368 4 106 2.88E-31 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 Pfam PF00120 Glutamine synthetase, catalytic domain 108 442 8.4E-140 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 236 251 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Theos_0515 5909cf1a04ebf6563f4c090c86ee0363 446 SMART SM01230 107 356 4.6E-138 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 Pfam PF02629 CoA binding domain 6 98 1.7E-32 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 PRINTS PR01798 Succinyl-CoA synthase signature 176 194 1.1E-32 T 14-10-2018 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 PRINTS PR01798 Succinyl-CoA synthase signature 207 220 1.1E-32 T 14-10-2018 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 PRINTS PR01798 Succinyl-CoA synthase signature 239 256 1.1E-32 T 14-10-2018 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 PRINTS PR01798 Succinyl-CoA synthase signature 81 98 1.1E-32 T 14-10-2018 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 SMART SM00881 3 99 1.0E-37 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 287 41.152 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 SUPERFAMILY SSF51735 2 120 7.48E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 PIRSF PIRSF001553 1 288 4.5E-130 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 SUPERFAMILY SSF52210 122 284 4.84E-52 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 2 287 7.6E-127 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 Pfam PF00549 CoA-ligase 150 268 5.1E-15 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 Gene3D G3DSA:3.40.50.261 123 288 7.1E-67 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 151 180 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 Gene3D G3DSA:3.40.50.720 1 122 2.4E-50 T 14-10-2018 Theos_0765 74ff2fe63154dd8a4505439ce534bdbf 288 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 235 248 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 SMART SM00345 16 74 1.0E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 Pfam PF07729 FCD domain 84 206 3.0E-29 T 14-10-2018 IPR011711 GntR, C-terminal Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 Gene3D G3DSA:1.10.10.10 9 75 7.4E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 SUPERFAMILY SSF48008 79 214 9.94E-32 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 Gene3D G3DSA:1.20.120.530 78 218 5.2E-36 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 SUPERFAMILY SSF46785 8 102 2.99E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 6.2E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Theos_1564 9c9e72f2e69448ed98a930495802b1a4 219 SMART SM00895 84 206 2.3E-27 T 14-10-2018 IPR011711 GntR, C-terminal Theos_0935 730555e11369d065c3b3b577b6ea2060 205 Pfam PF08798 CRISPR associated protein 1 205 2.8E-52 T 14-10-2018 IPR010179 CRISPR-associated protein Cse3 Theos_0935 730555e11369d065c3b3b577b6ea2060 205 SMART SM01101 1 205 5.5E-57 T 14-10-2018 IPR010179 CRISPR-associated protein Cse3 Theos_0935 730555e11369d065c3b3b577b6ea2060 205 Gene3D G3DSA:3.30.70.1210 88 204 1.1E-33 T 14-10-2018 Theos_0935 730555e11369d065c3b3b577b6ea2060 205 SUPERFAMILY SSF117987 1 78 1.39E-23 T 14-10-2018 Theos_0935 730555e11369d065c3b3b577b6ea2060 205 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 1 205 9.4E-23 T 14-10-2018 IPR010179 CRISPR-associated protein Cse3 Theos_0935 730555e11369d065c3b3b577b6ea2060 205 SUPERFAMILY SSF117987 89 205 2.14E-27 T 14-10-2018 Theos_0935 730555e11369d065c3b3b577b6ea2060 205 Gene3D G3DSA:3.30.70.1200 1 87 5.1E-28 T 14-10-2018 Theos_2482 fe937a3e19880beb1b52513ff305b951 214 Pfam PF13560 Helix-turn-helix domain 15 71 4.0E-9 T 14-10-2018 Theos_2482 fe937a3e19880beb1b52513ff305b951 214 Gene3D G3DSA:1.10.260.40 13 79 2.0E-12 T 14-10-2018 Theos_2482 fe937a3e19880beb1b52513ff305b951 214 SUPERFAMILY SSF47413 14 78 6.48E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Theos_2482 fe937a3e19880beb1b52513ff305b951 214 SMART SM00530 15 73 1.1E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 594 606 1.2E-25 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 519 529 1.2E-25 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 223 237 1.2E-25 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 571 590 1.2E-25 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 373 387 1.2E-25 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 112 678 7.8E-188 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 Pfam PF00702 haloacid dehalogenase-like hydrolase 369 585 7.4E-46 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 Gene3D G3DSA:3.40.1110.10 384 504 2.7E-91 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 SUPERFAMILY SSF56784 372 676 8.8E-56 T 14-10-2018 IPR036412 HAD-like superfamily Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 SUPERFAMILY SSF81653 176 273 5.36E-27 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 Gene3D G3DSA:2.70.150.20 161 277 1.4E-38 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 SUPERFAMILY SSF81665 132 632 3.14E-16 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 375 381 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 Gene3D G3DSA:3.40.50.1000 354 623 2.7E-91 T 14-10-2018 IPR023214 HAD superfamily Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 Pfam PF00122 E1-E2 ATPase 173 353 2.9E-56 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 149 650 1.6E-89 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00943 Copper-transporting ATPase signature 163 181 2.8E-11 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00943 Copper-transporting ATPase signature 97 116 2.8E-11 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00943 Copper-transporting ATPase signature 549 566 2.8E-11 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00943 Copper-transporting ATPase signature 296 310 2.8E-11 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 PRINTS PR00943 Copper-transporting ATPase signature 644 658 2.8E-11 T 14-10-2018 Theos_0087 e7a6ed47663adec0d4534ae200a16d52 685 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 94 680 1.7E-186 T 14-10-2018 Theos_1440 0f2ccf39e4b359f9f214cc0903b8d36f 418 PIRSF PIRSF001549 1 416 1.9E-104 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Theos_1440 0f2ccf39e4b359f9f214cc0903b8d36f 418 Gene3D G3DSA:3.40.50.800 321 415 9.3E-19 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily Theos_1440 0f2ccf39e4b359f9f214cc0903b8d36f 418 Pfam PF13393 Histidyl-tRNA synthetase 5 309 4.6E-38 T 14-10-2018 Theos_1440 0f2ccf39e4b359f9f214cc0903b8d36f 418 Gene3D G3DSA:3.30.930.10 1 320 1.9E-104 T 14-10-2018 Theos_1440 0f2ccf39e4b359f9f214cc0903b8d36f 418 SUPERFAMILY SSF52954 325 417 1.78E-16 T 14-10-2018 Theos_1440 0f2ccf39e4b359f9f214cc0903b8d36f 418 SUPERFAMILY SSF55681 3 313 2.49E-92 T 14-10-2018 Theos_1440 0f2ccf39e4b359f9f214cc0903b8d36f 418 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 415 30.626 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Theos_1440 0f2ccf39e4b359f9f214cc0903b8d36f 418 Pfam PF03129 Anticodon binding domain 328 411 6.9E-9 T 14-10-2018 IPR004154 Anticodon-binding Theos_1440 0f2ccf39e4b359f9f214cc0903b8d36f 418 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 2 404 8.8E-136 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Theos_1888 64228ab1b4cc49b636e633c99e296a2f 325 SUPERFAMILY SSF102114 3 276 3.66E-68 T 14-10-2018 Theos_1888 64228ab1b4cc49b636e633c99e296a2f 325 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 3 325 3.1E-102 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1888 64228ab1b4cc49b636e633c99e296a2f 325 Pfam PF06463 Molybdenum Cofactor Synthesis C 183 307 5.6E-27 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1888 64228ab1b4cc49b636e633c99e296a2f 325 Pfam PF04055 Radical SAM superfamily 16 176 6.1E-31 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_1888 64228ab1b4cc49b636e633c99e296a2f 325 Pfam PF13353 4Fe-4S single cluster domain 20 121 5.9E-6 T 14-10-2018 Theos_1888 64228ab1b4cc49b636e633c99e296a2f 325 SMART SM00729 12 218 5.7E-13 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_1888 64228ab1b4cc49b636e633c99e296a2f 325 Gene3D G3DSA:3.20.20.70 1 325 3.4E-80 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 SUPERFAMILY SSF51735 1 182 2.25E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 329 45.816 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 2.1E-137 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 PIRSF PIRSF000116 201 333 2.3E-15 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 PIRSF PIRSF000116 4 206 1.5E-48 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 Gene3D G3DSA:3.40.50.720 1 181 2.2E-80 T 14-10-2018 Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 1.1E-62 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 SUPERFAMILY SSF48179 183 329 1.05E-66 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 Gene3D G3DSA:1.10.3730.40 182 335 1.0E-66 T 14-10-2018 Theos_1229 bf9f8fc006cc43125dc58ba0165b8f32 336 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 7.9E-78 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Theos_0994 62af48eb699a4c0ea8a80a949690fce5 663 SUPERFAMILY SSF53720 5 488 2.49E-77 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_0994 62af48eb699a4c0ea8a80a949690fce5 663 Gene3D G3DSA:3.40.309.10 257 464 4.2E-130 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Theos_0994 62af48eb699a4c0ea8a80a949690fce5 663 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 3 660 0.0 T 14-10-2018 IPR011966 Phenylacetic acid degradation protein PaaN KEGG: 00360+3.3.2.12+1.2.1.91 Theos_0994 62af48eb699a4c0ea8a80a949690fce5 663 Pfam PF01575 MaoC like domain 528 641 2.7E-26 T 14-10-2018 IPR002539 MaoC-like dehydratase domain Theos_0994 62af48eb699a4c0ea8a80a949690fce5 663 Gene3D G3DSA:3.10.129.10 520 663 1.5E-44 T 14-10-2018 Theos_0994 62af48eb699a4c0ea8a80a949690fce5 663 Gene3D G3DSA:3.40.605.10 9 476 4.2E-130 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_0994 62af48eb699a4c0ea8a80a949690fce5 663 SUPERFAMILY SSF54637 517 660 2.13E-40 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_0994 62af48eb699a4c0ea8a80a949690fce5 663 Pfam PF00171 Aldehyde dehydrogenase family 11 444 2.0E-58 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Theos_0762 113fac7adb89d2089a471093e34340c3 405 Pfam PF13840 ACT domain 337 397 8.2E-11 T 14-10-2018 IPR027795 CASTOR, ACT domain Theos_0762 113fac7adb89d2089a471093e34340c3 405 Gene3D G3DSA:3.30.70.260 334 403 1.0E-23 T 14-10-2018 Theos_0762 113fac7adb89d2089a471093e34340c3 405 Gene3D G3DSA:3.40.1160.10 1 255 2.4E-86 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_0762 113fac7adb89d2089a471093e34340c3 405 SUPERFAMILY SSF55021 249 346 1.62E-17 T 14-10-2018 Theos_0762 113fac7adb89d2089a471093e34340c3 405 SUPERFAMILY SSF53633 4 240 9.43E-72 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_0762 113fac7adb89d2089a471093e34340c3 405 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Theos_0762 113fac7adb89d2089a471093e34340c3 405 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 402 4.9E-125 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Theos_0762 113fac7adb89d2089a471093e34340c3 405 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 401 1.7E-104 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Theos_0762 113fac7adb89d2089a471093e34340c3 405 SUPERFAMILY SSF55021 333 403 3.05E-20 T 14-10-2018 Theos_0762 113fac7adb89d2089a471093e34340c3 405 Pfam PF01842 ACT domain 266 322 2.2E-8 T 14-10-2018 IPR002912 ACT domain Theos_0762 113fac7adb89d2089a471093e34340c3 405 Pfam PF00696 Amino acid kinase family 3 229 3.0E-52 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Theos_0762 113fac7adb89d2089a471093e34340c3 405 PIRSF PIRSF000726 1 66 5.8E-20 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Theos_0762 113fac7adb89d2089a471093e34340c3 405 PIRSF PIRSF000726 60 405 6.0E-110 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Theos_0762 113fac7adb89d2089a471093e34340c3 405 Gene3D G3DSA:3.30.70.260 259 333 1.0E-30 T 14-10-2018 Theos_1915 051b626f6a16d565f33583b86956677d 388 SUPERFAMILY SSF103473 4 381 3.79E-50 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1915 051b626f6a16d565f33583b86956677d 388 PRINTS PR01035 Tetracycline resistance protein signature 139 161 1.6E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Theos_1915 051b626f6a16d565f33583b86956677d 388 PRINTS PR01035 Tetracycline resistance protein signature 13 29 1.6E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Theos_1915 051b626f6a16d565f33583b86956677d 388 PRINTS PR01035 Tetracycline resistance protein signature 275 296 1.6E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Theos_1915 051b626f6a16d565f33583b86956677d 388 PRINTS PR01035 Tetracycline resistance protein signature 336 359 1.6E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Theos_1915 051b626f6a16d565f33583b86956677d 388 Gene3D G3DSA:1.20.1250.20 3 382 2.8E-55 T 14-10-2018 Theos_1915 051b626f6a16d565f33583b86956677d 388 Pfam PF07690 Major Facilitator Superfamily 7 295 6.7E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 SUPERFAMILY SSF52440 1 114 8.06E-30 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Theos_0658 008a6948d056b77dfdd52d123dac803d 320 Gene3D G3DSA:3.30.470.20 109 316 2.8E-83 T 14-10-2018 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 Gene3D G3DSA:3.40.50.20 1 104 5.5E-35 T 14-10-2018 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 SUPERFAMILY SSF56059 115 318 4.42E-57 T 14-10-2018 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 Gene3D G3DSA:3.30.1490.20 132 188 2.8E-83 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 Pfam PF07478 D-ala D-ala ligase C-terminus 123 315 8.2E-65 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 318 39.852 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 82 93 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 317 1.0E-97 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 Pfam PF01820 D-ala D-ala ligase N-terminus 2 104 6.8E-22 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 261 288 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 PIRSF PIRSF039102 1 60 9.2E-7 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_0658 008a6948d056b77dfdd52d123dac803d 320 PIRSF PIRSF039102 69 320 1.4E-90 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_0913 9a5c3fdc86c0fc3450fb68275ec7da25 164 SMART SM00909 62 153 9.9E-7 T 14-10-2018 IPR019606 GerMN domain Theos_0913 9a5c3fdc86c0fc3450fb68275ec7da25 164 Pfam PF10646 Sporulation and spore germination 64 149 9.5E-8 T 14-10-2018 IPR019606 GerMN domain Theos_1782 a611c62c721935850b724bf30945f706 469 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 312 2.5E-108 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Theos_1782 a611c62c721935850b724bf30945f706 469 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 8 19 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1782 a611c62c721935850b724bf30945f706 469 Gene3D G3DSA:1.10.8.70 323 370 1.2E-21 T 14-10-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 Theos_1782 a611c62c721935850b724bf30945f706 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 5 17 2.9E-21 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Theos_1782 a611c62c721935850b724bf30945f706 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 34 47 2.9E-21 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Theos_1782 a611c62c721935850b724bf30945f706 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 185 195 2.9E-21 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Theos_1782 a611c62c721935850b724bf30945f706 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 30 2.9E-21 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Theos_1782 a611c62c721935850b724bf30945f706 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 201 209 2.9E-21 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Theos_1782 a611c62c721935850b724bf30945f706 469 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 1 467 31.567 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Theos_1782 a611c62c721935850b724bf30945f706 469 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 465 1.0E-139 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Theos_1782 a611c62c721935850b724bf30945f706 469 SUPERFAMILY SSF52374 1 300 1.53E-112 T 14-10-2018 Theos_1782 a611c62c721935850b724bf30945f706 469 Gene3D G3DSA:3.40.50.620 1 321 7.7E-138 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1782 a611c62c721935850b724bf30945f706 469 SUPERFAMILY SSF48163 306 467 3.14E-47 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Theos_1782 a611c62c721935850b724bf30945f706 469 Gene3D G3DSA:1.10.10.350 371 468 2.2E-31 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 SUPERFAMILY SSF52540 233 912 1.95E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 SMART SM00487 1006 1211 1.1E-26 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 SMART SM00487 238 546 0.0017 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 SMART SM00491 799 926 0.0011 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Pfam PF00271 Helicase conserved C-terminal domain 1222 1330 2.5E-14 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Gene3D G3DSA:3.40.50.300 764 938 2.8E-15 T 14-10-2018 Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 SUPERFAMILY SSF52540 1052 1350 4.27E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 SMART SM00479 8 181 2.4E-25 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Gene3D G3DSA:3.30.420.10 6 181 5.6E-34 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Gene3D G3DSA:3.40.50.300 1202 1416 3.8E-42 T 14-10-2018 Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Pfam PF13307 Helicase C-terminal domain 785 938 8.7E-17 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Pfam PF16124 RecQ zinc-binding 1539 1587 3.8E-8 T 14-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Gene3D G3DSA:1.10.10.10 1533 1715 2.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Pfam PF00929 Exonuclease 10 171 6.0E-16 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 1012 1372 4.6E-84 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Pfam PF00270 DEAD/DEAH box helicase 1013 1183 4.3E-21 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 SUPERFAMILY SSF53098 8 181 6.91E-35 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 Gene3D G3DSA:3.40.50.300 970 1201 2.4E-57 T 14-10-2018 Theos_2277 7cbbfce9a7608f5070c865671be5180c 1716 SMART SM00490 1248 1331 9.5E-26 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_0396 2ea6a7e735df10915f3b76006cb8fabd 376 Pfam PF00557 Metallopeptidase family M24 149 359 1.1E-35 T 14-10-2018 IPR000994 Peptidase M24 Theos_0396 2ea6a7e735df10915f3b76006cb8fabd 376 SUPERFAMILY SSF55920 142 370 1.31E-39 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like Theos_0396 2ea6a7e735df10915f3b76006cb8fabd 376 Gene3D G3DSA:3.90.230.10 142 373 2.1E-42 T 14-10-2018 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 97 111 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 SUPERFAMILY SSF55174 3 77 3.03E-14 T 14-10-2018 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 Gene3D G3DSA:3.30.70.580 63 222 1.8E-50 T 14-10-2018 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 219 8.6E-40 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 SUPERFAMILY SSF55120 62 222 5.28E-37 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 Gene3D G3DSA:3.10.290.10 1 56 3.3E-14 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 Pfam PF01479 S4 domain 2 46 2.4E-14 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 Pfam PF00849 RNA pseudouridylate synthase 62 189 3.4E-17 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 Gene3D G3DSA:3.30.70.1560 126 206 1.8E-50 T 14-10-2018 Theos_0419 9fe00e107ba8f4e510b6ec719b295137 237 SMART SM00363 2 62 1.6E-12 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0089 2ed8d744bfb91284e332610f914af68d 129 SUPERFAMILY SSF103247 6 127 3.01E-34 T 14-10-2018 IPR035923 TT1751-like domain superfamily Theos_0089 2ed8d744bfb91284e332610f914af68d 129 Gene3D G3DSA:3.30.310.70 1 129 2.2E-54 T 14-10-2018 IPR035923 TT1751-like domain superfamily Theos_0089 2ed8d744bfb91284e332610f914af68d 129 Pfam PF03625 Domain of unknown function DUF302 34 96 1.9E-23 T 14-10-2018 IPR005180 Domain of unknown function DUF302 Theos_0089 2ed8d744bfb91284e332610f914af68d 129 PIRSF PIRSF021774 1 129 3.1E-41 T 14-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 Theos_1109 8129ca4ec858df2609c844ff47fdd8c2 416 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 116 1.2E-6 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_1109 8129ca4ec858df2609c844ff47fdd8c2 416 Gene3D G3DSA:1.10.8.10 109 219 1.1E-95 T 14-10-2018 Theos_1109 8129ca4ec858df2609c844ff47fdd8c2 416 Gene3D G3DSA:1.10.8.60 311 413 4.8E-31 T 14-10-2018 Theos_1109 8129ca4ec858df2609c844ff47fdd8c2 416 Gene3D G3DSA:3.40.50.300 5 308 1.1E-95 T 14-10-2018 Theos_1109 8129ca4ec858df2609c844ff47fdd8c2 416 Pfam PF07724 AAA domain (Cdc48 subfamily) 188 305 3.6E-38 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_1109 8129ca4ec858df2609c844ff47fdd8c2 416 SMART SM00382 48 308 9.7E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1109 8129ca4ec858df2609c844ff47fdd8c2 416 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 381 9.0E-5 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Theos_1109 8129ca4ec858df2609c844ff47fdd8c2 416 SMART SM01086 311 404 1.6E-11 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Theos_1109 8129ca4ec858df2609c844ff47fdd8c2 416 SUPERFAMILY SSF52540 2 413 2.26E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2179 133d93f189672f189d8f0acdb12a02a9 257 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 234 7.1E-68 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Theos_2179 133d93f189672f189d8f0acdb12a02a9 257 Pfam PF01975 Survival protein SurE 3 185 8.1E-56 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Theos_2179 133d93f189672f189d8f0acdb12a02a9 257 SUPERFAMILY SSF64167 1 249 1.7E-80 T 14-10-2018 Theos_2179 133d93f189672f189d8f0acdb12a02a9 257 Gene3D G3DSA:3.40.1210.10 1 245 3.9E-87 T 14-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Theos_2179 133d93f189672f189d8f0acdb12a02a9 257 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 251 36.813 T 14-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Theos_1893 f3fb5ef10c4927ca8ac18e81a616d085 301 SMART SM00382 30 222 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1893 f3fb5ef10c4927ca8ac18e81a616d085 301 SUPERFAMILY SSF52540 4 227 2.21E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1893 f3fb5ef10c4927ca8ac18e81a616d085 301 Gene3D G3DSA:3.40.50.300 2 232 8.5E-57 T 14-10-2018 Theos_1893 f3fb5ef10c4927ca8ac18e81a616d085 301 Pfam PF00005 ABC transporter 22 164 5.7E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1832 cc61c27c679273ad851b2552b58bbbfe 327 Gene3D G3DSA:3.40.50.300 5 326 2.4E-106 T 14-10-2018 Theos_1832 cc61c27c679273ad851b2552b58bbbfe 327 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1832 cc61c27c679273ad851b2552b58bbbfe 327 SMART SM00382 43 236 1.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1832 cc61c27c679273ad851b2552b58bbbfe 327 Pfam PF00005 ABC transporter 35 186 1.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1832 cc61c27c679273ad851b2552b58bbbfe 327 SUPERFAMILY SSF52540 7 257 1.24E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1832 cc61c27c679273ad851b2552b58bbbfe 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 303 9.0E-17 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Theos_1832 cc61c27c679273ad851b2552b58bbbfe 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 322 1.7E-27 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Theos_0113 8454ee29f324f52e25d76b383394127d 252 SUPERFAMILY SSF52540 6 231 9.13E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0113 8454ee29f324f52e25d76b383394127d 252 Pfam PF00005 ABC transporter 21 172 1.3E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0113 8454ee29f324f52e25d76b383394127d 252 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 244 2.3E-101 T 14-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 Theos_0113 8454ee29f324f52e25d76b383394127d 252 Gene3D G3DSA:3.40.50.300 3 252 1.2E-65 T 14-10-2018 Theos_0113 8454ee29f324f52e25d76b383394127d 252 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 TIGRFAM TIGR01529 argR_whole: arginine repressor 6 150 2.9E-51 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 PRINTS PR01467 Bacterial arginine repressor signature 22 35 2.9E-23 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 PRINTS PR01467 Bacterial arginine repressor signature 120 135 2.9E-23 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 PRINTS PR01467 Bacterial arginine repressor signature 38 53 2.9E-23 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 PRINTS PR01467 Bacterial arginine repressor signature 90 103 2.9E-23 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 SUPERFAMILY SSF55252 82 149 2.49E-17 T 14-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 Pfam PF01316 Arginine repressor, DNA binding domain 4 66 2.0E-23 T 14-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 Hamap MF_00173 Arginine repressor [argR]. 1 152 57.984 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 Pfam PF02863 Arginine repressor, C-terminal domain 82 147 8.1E-24 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 SUPERFAMILY SSF46785 2 66 8.08E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 Gene3D G3DSA:1.10.10.10 5 67 5.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 89 138 3.0E-11 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 Theos_0642 b0e3082e6968502d6ea5e9725958d7cc 152 Gene3D G3DSA:3.30.1360.40 71 151 3.9E-24 T 14-10-2018 Theos_0757 3acd8578736a478ccd670873cda1c7df 371 SUPERFAMILY SSF48695 43 365 4.32E-22 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily Theos_0757 3acd8578736a478ccd670873cda1c7df 371 Gene3D G3DSA:1.10.1130.10 36 190 7.8E-6 T 14-10-2018 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 SUPERFAMILY SSF53671 1 296 1.31E-90 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 294 5.8E-23 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 145 1.1E-37 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 296 1.3E-89 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 76 85 1.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 131 148 1.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 213 222 1.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 253 258 1.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 1.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 277 291 1.8E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 Gene3D G3DSA:3.40.50.1370 132 275 8.0E-87 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 2.2E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 2.2E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 249 258 2.2E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 261 284 2.2E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 298 39.359 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0554 9dca6205dc7c707a09a3947b54402c15 301 Gene3D G3DSA:3.40.50.1370 7 292 8.0E-87 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Theos_1736 90c34caa63363046c95cb9732809043b 324 Gene3D G3DSA:3.40.190.90 124 285 6.7E-123 T 14-10-2018 Theos_1736 90c34caa63363046c95cb9732809043b 324 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 4 311 4.4E-129 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Theos_1736 90c34caa63363046c95cb9732809043b 324 SUPERFAMILY SSF56655 2 314 3.11E-96 T 14-10-2018 Theos_1736 90c34caa63363046c95cb9732809043b 324 PIRSF PIRSF004532 2 321 4.0E-124 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Theos_1736 90c34caa63363046c95cb9732809043b 324 Gene3D G3DSA:3.30.540.10 8 311 6.7E-123 T 14-10-2018 Theos_1736 90c34caa63363046c95cb9732809043b 324 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 4 315 6.6E-108 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Theos_0267 166b8230fcbc34b9ccfa3b293f123f59 299 Gene3D G3DSA:2.70.70.10 139 294 2.1E-49 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_0267 166b8230fcbc34b9ccfa3b293f123f59 299 SUPERFAMILY SSF51261 157 292 1.67E-53 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_0267 166b8230fcbc34b9ccfa3b293f123f59 299 Pfam PF01551 Peptidase family M23 194 288 7.6E-33 T 14-10-2018 IPR016047 Peptidase M23 Theos_2169 3aee64e0b3eecb5d1a943c207075ca26 143 Gene3D G3DSA:3.10.580.10 1 141 9.1E-46 T 14-10-2018 Theos_2169 3aee64e0b3eecb5d1a943c207075ca26 143 Pfam PF00571 CBS domain 71 124 4.4E-17 T 14-10-2018 IPR000644 CBS domain Theos_2169 3aee64e0b3eecb5d1a943c207075ca26 143 Pfam PF00571 CBS domain 15 60 2.4E-8 T 14-10-2018 IPR000644 CBS domain Theos_2169 3aee64e0b3eecb5d1a943c207075ca26 143 SUPERFAMILY SSF54631 1 137 2.02E-35 T 14-10-2018 Theos_2169 3aee64e0b3eecb5d1a943c207075ca26 143 SMART SM00116 13 60 4.6E-6 T 14-10-2018 IPR000644 CBS domain Theos_2169 3aee64e0b3eecb5d1a943c207075ca26 143 SMART SM00116 78 125 2.5E-14 T 14-10-2018 IPR000644 CBS domain Theos_1858 0d0df85154573cdeeaf7a3b214ea62bd 349 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 334 3.0E-65 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Theos_1858 0d0df85154573cdeeaf7a3b214ea62bd 349 SUPERFAMILY SSF51395 1 339 2.75E-114 T 14-10-2018 Theos_1858 0d0df85154573cdeeaf7a3b214ea62bd 349 Gene3D G3DSA:3.20.20.70 1 349 1.2E-124 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_2201 ab36cd0bf1fdb307c711da9857ebd44c 102 Pfam PF12836 Helix-hairpin-helix motif 45 101 4.2E-20 T 14-10-2018 Theos_2201 ab36cd0bf1fdb307c711da9857ebd44c 102 SUPERFAMILY SSF81585 39 101 4.18E-21 T 14-10-2018 Theos_2201 ab36cd0bf1fdb307c711da9857ebd44c 102 Gene3D G3DSA:1.10.150.320 28 102 2.9E-30 T 14-10-2018 Theos_2201 ab36cd0bf1fdb307c711da9857ebd44c 102 SMART SM00278 80 99 0.33 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_2201 ab36cd0bf1fdb307c711da9857ebd44c 102 SMART SM00278 54 73 0.0028 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_0441 d527ddaef21c93072fb7116dffb19f8e 168 Pfam PF17248 Family of unknown function (DUF5317) 6 133 5.1E-35 T 14-10-2018 IPR035168 Protein of unknown function DUF5317 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 PIRSF PIRSF002162 1 177 3.0E-43 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.2E-26 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.2E-26 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.2E-26 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 SUPERFAMILY SSF56053 1 82 1.31E-25 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 175 8.8E-68 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.108 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 Pfam PF00347 Ribosomal protein L6 91 164 1.1E-15 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 Pfam PF00347 Ribosomal protein L6 12 82 4.9E-20 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 Gene3D G3DSA:3.90.930.12 1 82 5.0E-33 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 SUPERFAMILY SSF56053 83 176 3.4E-31 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0292 7102d8b62f7c7ecaba03534bee3a0b2d 180 Gene3D G3DSA:3.90.930.12 83 180 3.8E-35 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_2128 aba6167db0d30a4fb4b7bc21bc2729d8 375 SUPERFAMILY SSF51735 139 317 5.65E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2128 aba6167db0d30a4fb4b7bc21bc2729d8 375 SMART SM01002 148 310 1.9E-73 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Theos_2128 aba6167db0d30a4fb4b7bc21bc2729d8 375 SUPERFAMILY SSF52283 3 170 2.3E-49 T 14-10-2018 Theos_2128 aba6167db0d30a4fb4b7bc21bc2729d8 375 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 365 8.0E-66 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Theos_2128 aba6167db0d30a4fb4b7bc21bc2729d8 375 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 Theos_2128 aba6167db0d30a4fb4b7bc21bc2729d8 375 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 6 139 4.3E-44 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Theos_2128 aba6167db0d30a4fb4b7bc21bc2729d8 375 Gene3D G3DSA:3.40.50.720 139 317 1.6E-141 T 14-10-2018 Theos_2128 aba6167db0d30a4fb4b7bc21bc2729d8 375 Gene3D G3DSA:3.40.50.720 6 353 1.6E-141 T 14-10-2018 Theos_2128 aba6167db0d30a4fb4b7bc21bc2729d8 375 SMART SM01003 5 139 1.4E-63 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Theos_2262 b258369247a56eae2a3036af6e3bb10e 211 SUPERFAMILY SSF110296 140 208 8.63E-5 T 14-10-2018 Theos_0810 7331e5b03833d5dcad33b2a367ea5349 255 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 15 41 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 Theos_0810 7331e5b03833d5dcad33b2a367ea5349 255 Gene3D G3DSA:3.30.200.20 2 83 2.2E-12 T 14-10-2018 Theos_0810 7331e5b03833d5dcad33b2a367ea5349 255 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Theos_0810 7331e5b03833d5dcad33b2a367ea5349 255 SUPERFAMILY SSF56112 6 250 1.08E-58 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Theos_0810 7331e5b03833d5dcad33b2a367ea5349 255 Gene3D G3DSA:1.10.510.10 84 254 1.7E-40 T 14-10-2018 Theos_0810 7331e5b03833d5dcad33b2a367ea5349 255 SMART SM00220 9 252 3.4E-40 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Theos_0810 7331e5b03833d5dcad33b2a367ea5349 255 Pfam PF00069 Protein kinase domain 11 249 5.1E-39 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 Gene3D G3DSA:3.30.70.3130 2 89 3.1E-33 T 14-10-2018 Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 3 90 2.3E-32 T 14-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 324 383 1.2E-16 T 14-10-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 Gene3D G3DSA:2.30.130.60 393 454 1.2E-24 T 14-10-2018 Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 SUPERFAMILY SSF53335 3 298 1.59E-62 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 Gene3D G3DSA:3.40.50.150 90 392 3.2E-94 T 14-10-2018 Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 Pfam PF01189 16S rRNA methyltransferase RsmB/F 95 297 1.8E-44 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 105 115 3.4E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 221 237 3.4E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 76 90 3.4E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 281 298 3.4E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Theos_0431 85edf25d72f4e1fc659c32064aa67678 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 171 183 3.4E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Theos_2051 16f0d16c7d800d59bd9417e41e14c91e 354 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 10 353 6.6E-150 T 14-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 Theos_2051 16f0d16c7d800d59bd9417e41e14c91e 354 Gene3D G3DSA:3.30.70.360 160 266 1.4E-130 T 14-10-2018 Theos_2051 16f0d16c7d800d59bd9417e41e14c91e 354 SUPERFAMILY SSF53187 8 353 5.19E-46 T 14-10-2018 Theos_2051 16f0d16c7d800d59bd9417e41e14c91e 354 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 6 352 31.938 T 14-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 Theos_2051 16f0d16c7d800d59bd9417e41e14c91e 354 Gene3D G3DSA:3.40.630.10 16 341 1.4E-130 T 14-10-2018 Theos_2051 16f0d16c7d800d59bd9417e41e14c91e 354 Pfam PF01546 Peptidase family M20/M25/M40 64 349 8.5E-33 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 Theos_2013 c0c9b808f4e14c7d58d9e956dbfb90be 528 Pfam PF04326 Putative DNA-binding domain 46 119 7.1E-6 T 14-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 Theos_2013 c0c9b808f4e14c7d58d9e956dbfb90be 528 Gene3D G3DSA:3.30.565.60 234 389 1.2E-42 T 14-10-2018 IPR038475 RecG, C-terminal domain superfamily Theos_2013 c0c9b808f4e14c7d58d9e956dbfb90be 528 Gene3D G3DSA:1.10.10.10 409 470 9.8E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2013 c0c9b808f4e14c7d58d9e956dbfb90be 528 Gene3D G3DSA:3.30.950.30 8 133 9.7E-11 T 14-10-2018 IPR038461 Schlafen, AAA domain superfamily Theos_2013 c0c9b808f4e14c7d58d9e956dbfb90be 528 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 305 389 2.6E-21 T 14-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain Theos_2013 c0c9b808f4e14c7d58d9e956dbfb90be 528 SUPERFAMILY SSF46785 396 510 9.31E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0756 31e2daafffa2377c34a8e0c1dc97e301 162 SUPERFAMILY SSF55811 5 142 4.74E-38 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Theos_0756 31e2daafffa2377c34a8e0c1dc97e301 162 Gene3D G3DSA:3.90.79.10 1 162 3.7E-55 T 14-10-2018 Theos_0756 31e2daafffa2377c34a8e0c1dc97e301 162 Pfam PF00293 NUDIX domain 25 145 2.6E-20 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Theos_0756 31e2daafffa2377c34a8e0c1dc97e301 162 PRINTS PR00502 NUDIX hydrolase family signature 68 83 2.9E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_0756 31e2daafffa2377c34a8e0c1dc97e301 162 PRINTS PR00502 NUDIX hydrolase family signature 54 68 2.9E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_0756 31e2daafffa2377c34a8e0c1dc97e301 162 ProSitePatterns PS00893 Nudix box signature. 59 80 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Theos_0296 6999baf3f97eb5f50165f87614b80832 150 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 1.1E-34 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0296 6999baf3f97eb5f50165f87614b80832 150 SUPERFAMILY SSF52080 5 147 6.54E-40 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily Theos_0296 6999baf3f97eb5f50165f87614b80832 150 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 145 1.3E-26 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P Theos_0296 6999baf3f97eb5f50165f87614b80832 150 Gene3D G3DSA:3.100.10.10 72 150 1.7E-25 T 14-10-2018 Theos_0296 6999baf3f97eb5f50165f87614b80832 150 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 148 19.553 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 Theos_0296 6999baf3f97eb5f50165f87614b80832 150 ProSitePatterns PS00475 Ribosomal protein L15 signature. 113 142 - T 14-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0238 8213dc51bb0668757a028c08c6d4427e 359 PIRSF PIRSF001549 1 326 1.7E-51 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Theos_0238 8213dc51bb0668757a028c08c6d4427e 359 Gene3D G3DSA:3.30.930.10 1 308 4.8E-62 T 14-10-2018 Theos_0238 8213dc51bb0668757a028c08c6d4427e 359 Pfam PF13393 Histidyl-tRNA synthetase 5 297 7.5E-72 T 14-10-2018 Theos_0238 8213dc51bb0668757a028c08c6d4427e 359 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 12 340 27.285 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 Theos_0238 8213dc51bb0668757a028c08c6d4427e 359 SUPERFAMILY SSF55681 2 301 3.11E-55 T 14-10-2018 Theos_1486 77a6de73061fa0182bbb1744a4e76d71 112 Pfam PF03780 Asp23 family, cell envelope-related function 4 101 3.9E-17 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 36.244 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 SMART SM00322 60 125 5.3E-6 T 14-10-2018 IPR004087 K Homology domain GO:0003676 Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.0E-83 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 SUPERFAMILY SSF54821 108 206 2.49E-35 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 Pfam PF07650 KH domain 39 110 7.9E-18 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 SUPERFAMILY SSF54814 2 106 5.76E-38 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 Gene3D G3DSA:3.30.300.20 17 107 3.9E-31 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 Gene3D G3DSA:3.30.1140.32 108 208 1.4E-38 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0283 2f5fffd463a88450d26c6a300e58cd9b 239 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 200 1.1E-33 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_1221 629107730fc00f5bac6b4aeb0fca7598 227 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 121 1.5E-22 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 Theos_1221 629107730fc00f5bac6b4aeb0fca7598 227 Gene3D G3DSA:3.40.50.10320 1 227 1.3E-91 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_1221 629107730fc00f5bac6b4aeb0fca7598 227 SUPERFAMILY SSF102588 3 222 1.83E-59 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_1221 629107730fc00f5bac6b4aeb0fca7598 227 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 2 216 7.9E-64 T 14-10-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 291 1.1E-102 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 PIRSF PIRSF001438 1 300 3.1E-112 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 291 36.63 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 220 289 1.9E-18 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 SUPERFAMILY SSF53850 2 209 1.09E-74 T 14-10-2018 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 Gene3D G3DSA:3.40.190.10 93 192 1.7E-82 T 14-10-2018 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 Gene3D G3DSA:3.30.160.40 214 299 7.0E-24 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 PRINTS PR00151 Porphobilinogen deaminase signature 117 134 2.1E-30 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 PRINTS PR00151 Porphobilinogen deaminase signature 69 88 2.1E-30 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 PRINTS PR00151 Porphobilinogen deaminase signature 223 240 2.1E-30 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 PRINTS PR00151 Porphobilinogen deaminase signature 136 153 2.1E-30 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 224 240 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 203 2.2E-71 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 SUPERFAMILY SSF54782 213 299 3.79E-23 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2187 06f464342493ed7d18b87a7ac262e29a 301 Gene3D G3DSA:3.40.190.10 5 206 1.7E-82 T 14-10-2018 Theos_2462 40f41fb24fca07c65879f351580f607a 249 SUPERFAMILY SSF52540 3 242 2.61E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2462 40f41fb24fca07c65879f351580f607a 249 Pfam PF00005 ABC transporter 19 174 6.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2462 40f41fb24fca07c65879f351580f607a 249 Gene3D G3DSA:3.40.50.300 1 246 2.8E-60 T 14-10-2018 Theos_2462 40f41fb24fca07c65879f351580f607a 249 SMART SM00382 28 224 1.3E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2462 40f41fb24fca07c65879f351580f607a 249 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 1.9E-8 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Theos_0839 9f16cb21cb6cdf2f35be9fb98b2be10a 349 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 38 193 5.2E-26 T 14-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Theos_0839 9f16cb21cb6cdf2f35be9fb98b2be10a 349 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 226 343 4.2E-10 T 14-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Theos_0839 9f16cb21cb6cdf2f35be9fb98b2be10a 349 SUPERFAMILY SSF54197 36 194 6.29E-47 T 14-10-2018 IPR036265 HIT-like superfamily Theos_0839 9f16cb21cb6cdf2f35be9fb98b2be10a 349 SUPERFAMILY SSF54197 219 344 5.1E-28 T 14-10-2018 IPR036265 HIT-like superfamily Theos_0839 9f16cb21cb6cdf2f35be9fb98b2be10a 349 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 36 343 1.5E-31 T 14-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Theos_0839 9f16cb21cb6cdf2f35be9fb98b2be10a 349 Gene3D G3DSA:3.30.428.10 41 342 3.0E-78 T 14-10-2018 IPR036265 HIT-like superfamily Theos_0839 9f16cb21cb6cdf2f35be9fb98b2be10a 349 Gene3D G3DSA:3.30.428.10 69 192 3.0E-78 T 14-10-2018 IPR036265 HIT-like superfamily Theos_0839 9f16cb21cb6cdf2f35be9fb98b2be10a 349 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 168 185 - T 14-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Theos_0839 9f16cb21cb6cdf2f35be9fb98b2be10a 349 PIRSF PIRSF000808 29 346 8.4E-91 T 14-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Theos_0590 ab3205365708a1d23ca84457acc4c9c6 119 Pfam PF00072 Response regulator receiver domain 3 112 3.0E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0590 ab3205365708a1d23ca84457acc4c9c6 119 Gene3D G3DSA:3.40.50.12740 1 118 1.5E-36 T 14-10-2018 Theos_0590 ab3205365708a1d23ca84457acc4c9c6 119 SMART SM00448 1 112 2.4E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0590 ab3205365708a1d23ca84457acc4c9c6 119 SUPERFAMILY SSF52172 1 117 1.04E-34 T 14-10-2018 IPR011006 CheY-like superfamily Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 SUPERFAMILY SSF55781 87 241 1.55E-18 T 14-10-2018 Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 586 742 5.1E-41 T 14-10-2018 IPR000160 GGDEF domain Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 Gene3D G3DSA:3.30.450.40 246 415 2.0E-15 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 Gene3D G3DSA:3.30.450.40 422 587 1.6E-13 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 SMART SM00065 116 251 3.7E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 SMART SM00065 430 587 0.064 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 Pfam PF13185 GAF domain 115 238 2.3E-11 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 Pfam PF13185 GAF domain 264 404 5.4E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 Gene3D G3DSA:3.30.70.270 588 745 1.5E-49 T 14-10-2018 Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 SUPERFAMILY SSF55781 432 588 1.7E-9 T 14-10-2018 Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 SMART SM00267 579 745 8.1E-53 T 14-10-2018 IPR000160 GGDEF domain Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 SUPERFAMILY SSF55781 250 407 6.76E-10 T 14-10-2018 Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 Gene3D G3DSA:3.30.450.40 93 244 9.2E-18 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 Pfam PF00990 Diguanylate cyclase, GGDEF domain 590 740 7.4E-39 T 14-10-2018 IPR000160 GGDEF domain Theos_1025 318bcb1b096fb9315d28cdbec2fcacfa 745 SUPERFAMILY SSF55073 595 741 1.02E-42 T 14-10-2018 IPR029787 Nucleotide cyclase Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 413 2.5E-115 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 Gene3D G3DSA:1.10.287.40 1 49 6.3E-17 T 14-10-2018 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 Gene3D G3DSA:1.10.287.40 55 102 1.4E-7 T 14-10-2018 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 219 396 4.4E-25 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 SUPERFAMILY SSF46589 1 110 8.37E-23 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 PRINTS PR00981 Seryl-tRNA synthetase signature 271 284 1.3E-25 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 PRINTS PR00981 Seryl-tRNA synthetase signature 330 346 1.3E-25 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 PRINTS PR00981 Seryl-tRNA synthetase signature 348 364 1.3E-25 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 PRINTS PR00981 Seryl-tRNA synthetase signature 259 271 1.3E-25 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 PRINTS PR00981 Seryl-tRNA synthetase signature 313 326 1.3E-25 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 102 4.1E-21 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 Gene3D G3DSA:3.30.930.10 104 421 2.5E-109 T 14-10-2018 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 SUPERFAMILY SSF55681 114 420 5.56E-81 T 14-10-2018 Theos_1555 6bb35f4302c6b668ae51999edea275f8 422 PIRSF PIRSF001529 1 420 3.3E-121 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 Gene3D G3DSA:3.30.70.1450 141 228 3.4E-13 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 Gene3D G3DSA:3.30.70.1450 351 442 4.4E-7 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 SUPERFAMILY SSF51735 232 370 4.96E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1191 de8db131e99c154741b708b9d80dcb33 445 SUPERFAMILY SSF51735 1 150 2.28E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1191 de8db131e99c154741b708b9d80dcb33 445 PRINTS PR00335 TrkA potassium uptake protein signature 71 85 1.9E-14 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.9E-14 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 PRINTS PR00335 TrkA potassium uptake protein signature 58 68 1.9E-14 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 PRINTS PR00335 TrkA potassium uptake protein signature 18 32 1.9E-14 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 PRINTS PR00335 TrkA potassium uptake protein signature 47 57 1.9E-14 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 Gene3D G3DSA:3.40.50.720 1 140 2.7E-33 T 14-10-2018 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 Gene3D G3DSA:3.40.50.720 233 346 1.9E-33 T 14-10-2018 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 Pfam PF02080 TrkA-C domain 155 225 3.7E-10 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 Pfam PF02254 TrkA-N domain 3 90 7.1E-25 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 Pfam PF02254 TrkA-N domain 234 346 2.6E-27 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Theos_1191 de8db131e99c154741b708b9d80dcb33 445 SUPERFAMILY SSF116726 136 225 3.27E-11 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Theos_0835 3f57da733a37d6e1efd185cf23589fb0 127 Pfam PF01867 CRISPR associated protein Cas1 3 101 6.7E-12 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Theos_0835 3f57da733a37d6e1efd185cf23589fb0 127 Gene3D G3DSA:3.100.10.20 1 76 4.9E-13 T 14-10-2018 Theos_2135 c1724e0cd65c02fd49d37fb8859c3575 199 Pfam PF01351 Ribonuclease HII 19 192 2.2E-30 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain Theos_2135 c1724e0cd65c02fd49d37fb8859c3575 199 Gene3D G3DSA:3.30.420.10 7 197 1.8E-63 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Theos_2135 c1724e0cd65c02fd49d37fb8859c3575 199 Hamap MF_00052_B Ribonuclease HII [rnhB]. 17 193 31.753 T 14-10-2018 IPR022898 Ribonuclease HII GO:0004523 Theos_2135 c1724e0cd65c02fd49d37fb8859c3575 199 SUPERFAMILY SSF53098 11 195 3.79E-57 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 PRINTS PR00143 Citrate synthase signature 124 137 2.0E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 PRINTS PR00143 Citrate synthase signature 328 342 2.0E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 PRINTS PR00143 Citrate synthase signature 195 223 2.0E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 PRINTS PR00143 Citrate synthase signature 308 324 2.0E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 PRINTS PR00143 Citrate synthase signature 248 268 2.0E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 PRINTS PR00143 Citrate synthase signature 173 188 2.0E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 SUPERFAMILY SSF48256 4 376 2.09E-131 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 376 4.3E-149 T 14-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 PIRSF PIRSF001369 1 376 6.1E-157 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 Gene3D G3DSA:1.10.580.10 20 347 3.6E-143 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 Pfam PF00285 Citrate synthase, C-terminal domain 6 358 7.3E-129 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Theos_0502 db669923b89ad75da9788a253d5f2d2b 376 Gene3D G3DSA:1.10.230.10 221 322 3.6E-143 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 SUPERFAMILY SSF52096 22 277 1.97E-80 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 159 177 1.1E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 196 213 1.1E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 247 256 1.1E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 125 139 1.1E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 225 236 1.1E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 6 276 3.9E-111 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 Gene3D G3DSA:3.90.226.10 22 278 3.2E-85 T 14-10-2018 Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 4 277 38.614 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0269 509d24f172e2da80b003440ef23b3c1b 285 Pfam PF01039 Carboxyl transferase domain 97 236 3.0E-14 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 Theos_1802 24488a22f028374d556198433f160f74 230 Pfam PF12146 Serine aminopeptidase, S33 3 210 1.9E-13 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 Theos_1802 24488a22f028374d556198433f160f74 230 SUPERFAMILY SSF53474 4 228 5.08E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1802 24488a22f028374d556198433f160f74 230 Gene3D G3DSA:3.40.50.1820 2 226 2.9E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1802 24488a22f028374d556198433f160f74 230 PIRSF PIRSF017388 1 228 6.5E-42 T 14-10-2018 IPR012354 Esterase/lipase GO:0052689 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00096 Glutamine amidotransferase superfamily signature 592 605 3.4E-11 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00096 Glutamine amidotransferase superfamily signature 506 517 3.4E-11 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00096 Glutamine amidotransferase superfamily signature 478 487 3.4E-11 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 475 489 8.6E-5 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 506 522 8.6E-5 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 Gene3D G3DSA:3.60.120.10 5 409 5.8E-118 T 14-10-2018 IPR005801 ADC synthase GO:0009058 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 Pfam PF00425 chorismate binding enzyme 151 398 1.6E-86 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 Gene3D G3DSA:3.40.50.880 435 615 1.1E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 SUPERFAMILY SSF52317 436 614 7.58E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 SUPERFAMILY SSF56322 16 406 1.44E-113 T 14-10-2018 IPR005801 ADC synthase GO:0009058 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00097 Anthranilate synthase component II signature 592 605 1.0E-25 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00097 Anthranilate synthase component II signature 506 517 1.0E-25 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00097 Anthranilate synthase component II signature 437 451 1.0E-25 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00097 Anthranilate synthase component II signature 478 487 1.0E-25 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00097 Anthranilate synthase component II signature 530 538 1.0E-25 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 PRINTS PR00097 Anthranilate synthase component II signature 550 562 1.0E-25 T 14-10-2018 Theos_1342 a7937ae352c30f1af498358a9e2d1c2b 616 Pfam PF00117 Glutamine amidotransferase class-I 439 613 1.1E-33 T 14-10-2018 IPR017926 Glutamine amidotransferase Theos_0695 388bb53bb8e4fd240fc0e137542674b4 155 Pfam PF02080 TrkA-C domain 87 155 1.0E-17 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Theos_0695 388bb53bb8e4fd240fc0e137542674b4 155 SUPERFAMILY SSF116726 84 155 1.16E-16 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Theos_0695 388bb53bb8e4fd240fc0e137542674b4 155 Gene3D G3DSA:3.30.70.1450 82 155 4.5E-17 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Theos_0695 388bb53bb8e4fd240fc0e137542674b4 155 PIRSF PIRSF005028 1 155 1.2E-49 T 14-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT Theos_1808 0b771dde693a81cff9530fb5389f3d87 128 SUPERFAMILY SSF81593 10 126 7.06E-27 T 14-10-2018 Theos_1808 0b771dde693a81cff9530fb5389f3d87 128 Gene3D G3DSA:1.20.120.330 4 127 1.7E-29 T 14-10-2018 Theos_1808 0b771dde693a81cff9530fb5389f3d87 128 Pfam PF05168 HEPN domain 9 124 3.2E-26 T 14-10-2018 IPR007842 HEPN domain Theos_1808 0b771dde693a81cff9530fb5389f3d87 128 SMART SM00748 12 118 2.1E-18 T 14-10-2018 IPR007842 HEPN domain Theos_1914 ee6c5a22495321605a7e7e6cbccd7133 271 Gene3D G3DSA:3.40.50.300 22 269 1.4E-72 T 14-10-2018 Theos_1914 ee6c5a22495321605a7e7e6cbccd7133 271 SUPERFAMILY SSF52540 24 265 1.77E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1914 ee6c5a22495321605a7e7e6cbccd7133 271 Pfam PF00005 ABC transporter 42 196 1.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1914 ee6c5a22495321605a7e7e6cbccd7133 271 SMART SM00382 49 247 2.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1914 ee6c5a22495321605a7e7e6cbccd7133 271 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1914 ee6c5a22495321605a7e7e6cbccd7133 271 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 25 271 2.2E-116 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 ProSitePatterns PS01244 Aconitase family signature 2. 398 411 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 Gene3D G3DSA:3.30.499.10 325 465 2.0E-47 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 5.3E-144 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 465 8.5E-185 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 ProSitePatterns PS00450 Aconitase family signature 1. 338 354 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 PRINTS PR00415 Aconitase family signature 119 132 1.8E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 PRINTS PR00415 Aconitase family signature 195 208 1.8E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 PRINTS PR00415 Aconitase family signature 108 116 1.8E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 PRINTS PR00415 Aconitase family signature 209 222 1.8E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 PRINTS PR00415 Aconitase family signature 398 411 1.8E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 PRINTS PR00415 Aconitase family signature 286 300 1.8E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 PRINTS PR00415 Aconitase family signature 133 148 1.8E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 PRINTS PR00415 Aconitase family signature 342 353 1.8E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 Gene3D G3DSA:3.30.499.20 4 286 6.2E-92 T 14-10-2018 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 55.964 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Theos_1249 146fe73cdb4258af5c52af73e4d722bb 470 SUPERFAMILY SSF53732 1 465 6.67E-154 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Theos_1480 dbefe616db2ffe637579f61d8d0e9ed6 185 Gene3D G3DSA:3.40.50.150 4 152 1.3E-17 T 14-10-2018 Theos_1480 dbefe616db2ffe637579f61d8d0e9ed6 185 SUPERFAMILY SSF53335 5 131 1.35E-18 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_2343 092c5b2968315d30f81445c721aedf8d 248 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 233 4.6E-50 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Theos_2343 092c5b2968315d30f81445c721aedf8d 248 Pfam PF01975 Survival protein SurE 3 184 5.6E-46 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Theos_2343 092c5b2968315d30f81445c721aedf8d 248 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 248 31.434 T 14-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Theos_2343 092c5b2968315d30f81445c721aedf8d 248 Gene3D G3DSA:3.40.1210.10 1 242 6.8E-82 T 14-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Theos_2343 092c5b2968315d30f81445c721aedf8d 248 SUPERFAMILY SSF64167 1 241 3.01E-70 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 Pfam PF14698 Argininosuccinate lyase C-terminal 367 434 3.1E-21 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 SUPERFAMILY SSF48557 8 457 2.04E-145 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 Gene3D G3DSA:1.10.275.50 1 108 8.2E-40 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 Pfam PF00206 Lyase 8 304 1.2E-75 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 457 43.073 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 TIGRFAM TIGR00838 argH: argininosuccinate lyase 5 459 1.5E-179 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 1.7E-61 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 1.7E-61 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00145 Argininosuccinate lyase family signature 314 333 1.7E-61 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 1.7E-61 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 1.7E-61 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 1.7E-61 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 Gene3D G3DSA:1.10.40.30 368 438 1.1E-153 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 Gene3D G3DSA:1.20.200.10 109 451 1.1E-153 T 14-10-2018 Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 6.6E-25 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 6.6E-25 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 6.6E-25 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0129 74c5f9c92ee8a3f52fbe00109bcedc32 464 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 6.6E-25 T 14-10-2018 IPR000362 Fumarate lyase family Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 Gene3D G3DSA:1.10.10.1600 496 571 5.5E-29 T 14-10-2018 Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 SUPERFAMILY SSF160975 892 939 2.09E-5 T 14-10-2018 Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 SUPERFAMILY SSF89550 7 260 2.35E-28 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 Pfam PF14579 Helix-hairpin-helix motif 866 952 5.5E-28 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 Pfam PF02811 PHP domain 9 184 7.5E-49 T 14-10-2018 IPR004013 PHP domain GO:0003824 Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 Gene3D G3DSA:3.20.20.140 1 284 3.0E-107 T 14-10-2018 Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 377 792 2.8E-166 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 SMART SM00481 8 77 1.3E-25 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 Gene3D G3DSA:1.10.150.870 830 943 2.7E-7 T 14-10-2018 Theos_2188 d02f6684d6dec936c34e938a84a94794 1221 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 361 1082 2.1E-283 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_2329 b43353cd2313e842173a2ebb5ff63d3b 338 SUPERFAMILY SSF53383 17 332 1.39E-55 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_2329 b43353cd2313e842173a2ebb5ff63d3b 338 Gene3D G3DSA:3.90.1150.10 23 328 4.9E-65 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_2329 b43353cd2313e842173a2ebb5ff63d3b 338 Pfam PF00155 Aminotransferase class I and II 49 328 4.8E-28 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Theos_2329 b43353cd2313e842173a2ebb5ff63d3b 338 Gene3D G3DSA:3.40.640.10 35 241 4.9E-65 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0611 28ca2d8bacfcfc0fdb18cc4ba520222e 286 Pfam PF03968 OstA-like protein 39 140 5.9E-5 T 14-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal Theos_0611 28ca2d8bacfcfc0fdb18cc4ba520222e 286 Gene3D G3DSA:2.60.450.10 67 185 2.5E-6 T 14-10-2018 Theos_2165 a3e523f0809de96c03f333cc09f19cfa 602 SUPERFAMILY SSF109998 330 464 4.32E-9 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily Theos_2165 a3e523f0809de96c03f333cc09f19cfa 602 SUPERFAMILY SSF54534 175 275 3.21E-13 T 14-10-2018 Theos_2165 a3e523f0809de96c03f333cc09f19cfa 602 SUPERFAMILY SSF109998 39 209 3.69E-20 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily Theos_2165 a3e523f0809de96c03f333cc09f19cfa 602 Gene3D G3DSA:1.10.4030.30 44 280 8.9E-28 T 14-10-2018 Theos_2165 a3e523f0809de96c03f333cc09f19cfa 602 Pfam PF13145 PPIC-type PPIASE domain 419 541 2.2E-12 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Theos_2165 a3e523f0809de96c03f333cc09f19cfa 602 Pfam PF13145 PPIC-type PPIASE domain 160 289 1.3E-18 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Theos_2165 a3e523f0809de96c03f333cc09f19cfa 602 Gene3D G3DSA:3.10.50.40 180 278 8.9E-28 T 14-10-2018 Theos_2165 a3e523f0809de96c03f333cc09f19cfa 602 Pfam PF13624 SurA N-terminal domain 8 149 3.4E-10 T 14-10-2018 Theos_2176 031d5f46d50e19faa7efd08ef6c00e69 304 Gene3D G3DSA:3.40.50.1100 7 296 2.2E-120 T 14-10-2018 Theos_2176 031d5f46d50e19faa7efd08ef6c00e69 304 TIGRFAM TIGR01139 cysK: cysteine synthase A 4 301 8.2E-124 T 14-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Theos_2176 031d5f46d50e19faa7efd08ef6c00e69 304 SUPERFAMILY SSF53686 3 302 2.62E-97 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Theos_2176 031d5f46d50e19faa7efd08ef6c00e69 304 TIGRFAM TIGR01136 cysKM: cysteine synthase 4 301 5.3E-123 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Theos_2176 031d5f46d50e19faa7efd08ef6c00e69 304 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 29 47 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 Theos_2176 031d5f46d50e19faa7efd08ef6c00e69 304 Gene3D G3DSA:3.40.50.1100 34 155 2.2E-120 T 14-10-2018 Theos_2176 031d5f46d50e19faa7efd08ef6c00e69 304 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 4 289 4.6E-68 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Theos_1523 69482235542f90dca310c74b69fbc1fd 413 SUPERFAMILY SSF53383 1 410 3.46E-93 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_1523 69482235542f90dca310c74b69fbc1fd 413 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 410 1.8E-102 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Theos_1523 69482235542f90dca310c74b69fbc1fd 413 PIRSF PIRSF001434 1 413 1.5E-117 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Theos_1523 69482235542f90dca310c74b69fbc1fd 413 Gene3D G3DSA:3.90.1150.10 279 413 2.9E-47 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_1523 69482235542f90dca310c74b69fbc1fd 413 Gene3D G3DSA:3.40.640.10 1 278 8.7E-88 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 SUPERFAMILY SSF51735 97 279 1.44E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 Gene3D G3DSA:3.40.50.720 22 302 4.5E-112 T 14-10-2018 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 Gene3D G3DSA:3.30.70.260 448 521 4.6E-23 T 14-10-2018 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 SUPERFAMILY SSF143548 314 443 1.6E-23 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 139 166 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 Gene3D G3DSA:3.30.1330.90 315 447 1.3E-25 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 SUPERFAMILY SSF52283 22 121 1.74E-32 T 14-10-2018 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 521 2.2E-181 T 14-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 Pfam PF01842 ACT domain 448 511 1.1E-12 T 14-10-2018 IPR002912 ACT domain Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 278 1.0E-61 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 SUPERFAMILY SSF55021 439 516 2.42E-17 T 14-10-2018 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 303 7.8E-32 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 188 210 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Theos_0959 7394d5dabefdfcdcca1bd55bd6abafbc 521 Gene3D G3DSA:3.40.50.720 94 276 4.5E-112 T 14-10-2018 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 55 106 2.0E-23 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 113 199 20.04 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 SUPERFAMILY SSF101386 115 204 3.36E-23 T 14-10-2018 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 30 102 1.3E-32 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 116 199 3.2E-28 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 Gene3D G3DSA:3.10.20.400 1 93 1.9E-38 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 117 200 2.1E-14 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 SUPERFAMILY SSF141734 4 108 1.7E-45 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 5 204 35.876 T 14-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 Gene3D G3DSA:1.10.287.1080 113 205 6.7E-28 T 14-10-2018 Theos_1643 aed651e17e2190488d12f2badf4f175d 208 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 3 106 30.397 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 SUPERFAMILY SSF52540 2 226 1.43E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 SMART SM00382 26 215 1.9E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 SMART SM00382 277 449 1.7 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 Pfam PF00005 ABC transporter 18 167 3.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 SUPERFAMILY SSF52540 267 477 1.26E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 Pfam PF00005 ABC transporter 268 415 3.8E-15 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 ProSitePatterns PS00211 ABC transporters family signature. 392 406 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 Gene3D G3DSA:3.40.50.300 251 488 1.1E-37 T 14-10-2018 Theos_0851 c60cb085743d67f3e8fc9a2f82201824 491 Gene3D G3DSA:3.40.50.300 1 246 7.7E-61 T 14-10-2018 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 Gene3D G3DSA:3.40.50.300 232 405 2.0E-5 T 14-10-2018 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 Pfam PF03704 Bacterial transcriptional activator domain 103 208 3.9E-18 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 Gene3D G3DSA:1.25.40.10 42 224 6.1E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 Gene3D G3DSA:1.25.40.10 840 953 1.1E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 SUPERFAMILY SSF48452 124 715 9.11E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 SUPERFAMILY SSF52540 236 478 5.83E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 Gene3D G3DSA:1.25.40.10 584 681 1.4E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 SUPERFAMILY SSF48452 765 932 1.37E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 Gene3D G3DSA:1.25.40.10 683 839 9.8E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 SMART SM00028 613 646 41.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 SMART SM00028 875 908 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 SMART SM00028 685 718 57.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 SMART SM00028 763 796 130.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 SMART SM01043 73 209 1.0E-32 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 Pfam PF13191 AAA ATPase domain 236 388 3.7E-12 T 14-10-2018 Theos_2249 6202a7b5cab9536d5b1fccd886020d62 962 SUPERFAMILY SSF48452 81 231 3.04E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 114 193 2.4E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 5.3E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 5.3E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 5.3E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 5.3E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 Gene3D G3DSA:3.40.50.1000 5 207 2.0E-38 T 14-10-2018 IPR023214 HAD superfamily Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 197 3.5E-13 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 82 197 2.1E-19 T 14-10-2018 Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 SUPERFAMILY SSF56784 1 209 7.54E-40 T 14-10-2018 IPR036412 HAD-like superfamily Theos_0383 e9e0ece9457105752137a322ccc4ba49 220 Gene3D G3DSA:1.10.150.720 18 95 2.0E-38 T 14-10-2018 Theos_0873 fa844fb5fbaf616023c5a3a9d2d05420 670 PIRSF PIRSF000549 1 668 1.2E-249 T 14-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 Theos_0873 fa844fb5fbaf616023c5a3a9d2d05420 670 SMART SM00763 23 406 3.7E-209 T 14-10-2018 IPR013153 PrkA AAA domain Theos_0873 fa844fb5fbaf616023c5a3a9d2d05420 670 Pfam PF06798 PrkA serine protein kinase C-terminal domain 410 660 5.3E-86 T 14-10-2018 IPR010650 PrkA C-terminal domain Theos_0873 fa844fb5fbaf616023c5a3a9d2d05420 670 SUPERFAMILY SSF52540 80 450 2.64E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0873 fa844fb5fbaf616023c5a3a9d2d05420 670 Pfam PF08298 PrkA AAA domain 24 404 2.1E-91 T 14-10-2018 IPR013153 PrkA AAA domain Theos_1898 8c0a11575009d55060e9abcfd7dabf0d 152 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 152 30.709 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Theos_1898 8c0a11575009d55060e9abcfd7dabf0d 152 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 151 2.8E-47 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Theos_1898 8c0a11575009d55060e9abcfd7dabf0d 152 Pfam PF02542 YgbB family 1 150 2.4E-46 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Theos_1898 8c0a11575009d55060e9abcfd7dabf0d 152 SUPERFAMILY SSF69765 1 151 9.42E-47 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Theos_1898 8c0a11575009d55060e9abcfd7dabf0d 152 Gene3D G3DSA:3.30.1330.50 1 152 1.9E-51 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Theos_1796 6b581fa8388d49cf00bc67f1c80504ae 216 SMART SM00100 6 127 1.2E-17 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_1796 6b581fa8388d49cf00bc67f1c80504ae 216 SMART SM00419 156 204 1.7E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_1796 6b581fa8388d49cf00bc67f1c80504ae 216 Gene3D G3DSA:2.60.120.10 1 139 5.0E-41 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_1796 6b581fa8388d49cf00bc67f1c80504ae 216 Pfam PF00027 Cyclic nucleotide-binding domain 26 110 1.7E-19 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_1796 6b581fa8388d49cf00bc67f1c80504ae 216 Pfam PF13545 Crp-like helix-turn-helix domain 145 210 3.9E-14 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_1796 6b581fa8388d49cf00bc67f1c80504ae 216 Gene3D G3DSA:1.10.10.10 140 216 1.8E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1796 6b581fa8388d49cf00bc67f1c80504ae 216 SUPERFAMILY SSF51206 2 137 8.64E-32 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Theos_1796 6b581fa8388d49cf00bc67f1c80504ae 216 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 74 91 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site Theos_1796 6b581fa8388d49cf00bc67f1c80504ae 216 SUPERFAMILY SSF46785 142 212 5.37E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Pfam PF13426 PAS domain 452 553 5.9E-17 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SUPERFAMILY SSF55785 63 185 7.89E-15 T 14-10-2018 IPR035965 PAS domain superfamily Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Gene3D G3DSA:1.10.3210.10 1018 1206 1.3E-75 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SUPERFAMILY SSF55785 324 432 9.57E-18 T 14-10-2018 IPR035965 PAS domain superfamily Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Pfam PF13188 PAS domain 321 373 1.4E-7 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00091 321 388 1.1E-8 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00091 206 270 87.0 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00091 566 631 1.1E-9 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00091 73 141 1.7E-6 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00091 441 507 2.0E-9 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Pfam PF13487 HD domain 1094 1155 5.0E-22 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SUPERFAMILY SSF55785 229 324 2.09E-9 T 14-10-2018 IPR035965 PAS domain superfamily Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SUPERFAMILY SSF55781 669 839 3.05E-18 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00065 700 848 3.9E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00065 869 1015 7.1E-16 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00471 1039 1174 1.2E-11 T 14-10-2018 IPR003607 HD/PDEase domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00086 638 678 0.02 T 14-10-2018 IPR001610 PAC motif Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00086 393 433 200.0 T 14-10-2018 IPR001610 PAC motif Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SMART SM00086 513 554 3.1E-9 T 14-10-2018 IPR001610 PAC motif Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 318 438 1.4E-16 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 562 682 3.4E-25 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 439 560 3.0E-21 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 73 196 5.6E-10 T 14-10-2018 IPR000014 PAS domain Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SUPERFAMILY SSF55785 551 676 3.89E-26 T 14-10-2018 IPR035965 PAS domain superfamily Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SUPERFAMILY SSF55781 834 1007 4.58E-24 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SUPERFAMILY SSF109604 1020 1204 2.28E-46 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Gene3D G3DSA:3.30.450.20 555 676 6.8E-26 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Pfam PF13185 GAF domain 699 838 7.0E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Pfam PF13185 GAF domain 873 1006 2.6E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Gene3D G3DSA:3.30.450.20 437 554 1.2E-35 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Gene3D G3DSA:3.30.450.20 186 313 1.5E-13 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Gene3D G3DSA:3.30.450.20 64 185 1.0E-16 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Gene3D G3DSA:3.30.450.40 677 848 1.7E-23 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Gene3D G3DSA:3.30.450.40 849 1017 3.0E-28 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Gene3D G3DSA:3.30.450.20 314 429 7.9E-19 T 14-10-2018 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Pfam PF08447 PAS fold 230 298 6.0E-10 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Pfam PF08447 PAS fold 97 166 1.9E-8 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 Pfam PF08447 PAS fold 588 663 1.7E-9 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Theos_1027 ac0b01db71cbcb9c5d40ef6717683acb 1208 SUPERFAMILY SSF55785 448 553 1.36E-29 T 14-10-2018 IPR035965 PAS domain superfamily Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 Pfam PF16193 AAA C-terminal domain 168 237 4.2E-18 T 14-10-2018 IPR032423 AAA C-terminal domain Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 Gene3D G3DSA:3.40.50.300 1 147 8.5E-40 T 14-10-2018 Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 SUPERFAMILY SSF52540 3 203 8.6E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 SMART SM00382 37 149 7.3E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 Pfam PF12002 MgsA AAA+ ATPase C terminal 239 403 7.1E-60 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 Gene3D G3DSA:1.10.8.60 149 214 1.3E-8 T 14-10-2018 Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 141 8.5E-14 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 Gene3D G3DSA:1.10.3710.10 316 414 8.5E-27 T 14-10-2018 Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 SUPERFAMILY SSF48019 223 405 1.7E-65 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Theos_0157 8507b7fef4dec1a3d024701018dd0b19 417 Gene3D G3DSA:1.20.272.10 215 315 1.5E-39 T 14-10-2018 Theos_0597 09249227fbf7357bb7a005c11ad9acdd 244 Gene3D G3DSA:1.10.10.200 1 82 3.2E-27 T 14-10-2018 IPR017856 Integrase-like, N-terminal Theos_0597 09249227fbf7357bb7a005c11ad9acdd 244 Gene3D G3DSA:3.30.70.980 136 201 5.6E-53 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0597 09249227fbf7357bb7a005c11ad9acdd 244 Gene3D G3DSA:3.30.70.980 87 234 5.6E-53 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0597 09249227fbf7357bb7a005c11ad9acdd 244 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 237 32.506 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0597 09249227fbf7357bb7a005c11ad9acdd 244 SUPERFAMILY SSF75625 3 237 3.79E-81 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0597 09249227fbf7357bb7a005c11ad9acdd 244 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 1.3E-82 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0597 09249227fbf7357bb7a005c11ad9acdd 244 Pfam PF01709 Transcriptional regulator 5 235 6.4E-84 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 125 144 2.0E-54 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 2.0E-54 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 2.0E-54 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 180 200 2.0E-54 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 2.0E-54 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 Gene3D G3DSA:3.30.420.40 147 312 9.4E-125 T 14-10-2018 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 SUPERFAMILY SSF53067 143 328 2.65E-49 T 14-10-2018 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 Gene3D G3DSA:3.90.640.10 179 254 9.4E-125 T 14-10-2018 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 Pfam PF06723 MreB/Mbl protein 5 330 1.2E-136 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 Gene3D G3DSA:3.30.420.40 7 322 9.4E-125 T 14-10-2018 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 5 330 6.4E-139 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Theos_0182 c7bdde83d6f077fe4fa59b669c80df7d 343 SUPERFAMILY SSF53067 6 141 2.68E-33 T 14-10-2018 Theos_0730 eafe786db0c5306717ebca4dd26a1f9c 194 Gene3D G3DSA:3.30.230.40 1 89 1.4E-29 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Theos_0730 eafe786db0c5306717ebca4dd26a1f9c 194 SUPERFAMILY SSF54211 2 84 4.17E-26 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_0730 eafe786db0c5306717ebca4dd26a1f9c 194 SUPERFAMILY SSF54211 87 181 4.3E-27 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_0730 eafe786db0c5306717ebca4dd26a1f9c 194 Gene3D G3DSA:3.30.230.40 90 194 5.2E-33 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Theos_0730 eafe786db0c5306717ebca4dd26a1f9c 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Theos_0730 eafe786db0c5306717ebca4dd26a1f9c 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 36.896 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Theos_0730 eafe786db0c5306717ebca4dd26a1f9c 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 176 2.2E-54 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Theos_0730 eafe786db0c5306717ebca4dd26a1f9c 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 TIGRFAM TIGR00615 recR: recombination protein RecR 2 192 9.2E-62 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 Pfam PF13662 Toprim domain 79 165 4.7E-23 T 14-10-2018 IPR006171 TOPRIM domain Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 Pfam PF02132 RecR protein 39 76 1.8E-9 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 Gene3D G3DSA:1.10.8.420 1 51 5.8E-14 T 14-10-2018 Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 SUPERFAMILY SSF111304 1 194 1.15E-64 T 14-10-2018 IPR023627 Recombination protein RecR Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 Hamap MF_00017 Recombination protein RecR [recR]. 1 194 85.615 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 Gene3D G3DSA:3.40.1360.10 75 194 2.1E-41 T 14-10-2018 Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 ProSitePatterns PS01300 RecR protein signature. 55 76 - T 14-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 SMART SM00278 12 31 0.0069 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_0344 bf581f1b4739ec7cc4dad2d46eb37887 194 SMART SM00493 78 161 1.9E-11 T 14-10-2018 IPR006171 TOPRIM domain Theos_2062 62e0dd35d7aef7ac8dae94ce82c3b869 144 SUPERFAMILY SSF52540 26 91 3.16E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2062 62e0dd35d7aef7ac8dae94ce82c3b869 144 Gene3D G3DSA:3.40.50.300 4 138 1.9E-29 T 14-10-2018 Theos_2062 62e0dd35d7aef7ac8dae94ce82c3b869 144 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 14 111 5.1E-23 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Theos_2062 62e0dd35d7aef7ac8dae94ce82c3b869 144 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 13 110 5.0E-27 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Theos_0305 44d1a0acd4799728a0987353bec00120 312 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 222 1.3E-24 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 243 305 2.5E-17 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 SUPERFAMILY SSF56553 50 172 1.22E-40 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 Gene3D G3DSA:3.30.1360.10 19 222 2.7E-90 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 SUPERFAMILY SSF47789 249 311 1.23E-14 T 14-10-2018 Theos_0305 44d1a0acd4799728a0987353bec00120 312 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 312 1.0E-14 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 Gene3D G3DSA:2.170.120.12 50 171 2.7E-90 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 SUPERFAMILY SSF55257 2 227 1.77E-32 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 Gene3D G3DSA:1.10.150.20 244 312 4.3E-21 T 14-10-2018 Theos_0305 44d1a0acd4799728a0987353bec00120 312 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 2 312 33.245 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 311 2.4E-100 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 SMART SM00662 20 228 2.3E-100 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0305 44d1a0acd4799728a0987353bec00120 312 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 154 1.0E-24 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0923 97e43c2f6080b97194e00d2619d9b775 412 Gene3D G3DSA:3.90.1150.10 3 401 3.1E-166 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0923 97e43c2f6080b97194e00d2619d9b775 412 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 220 257 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0923 97e43c2f6080b97194e00d2619d9b775 412 Gene3D G3DSA:3.40.640.10 61 305 3.1E-166 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0923 97e43c2f6080b97194e00d2619d9b775 412 Pfam PF00202 Aminotransferase class-III 30 399 3.3E-113 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0923 97e43c2f6080b97194e00d2619d9b775 412 PIRSF PIRSF000521 27 129 4.6E-10 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0923 97e43c2f6080b97194e00d2619d9b775 412 PIRSF PIRSF000521 172 404 2.4E-44 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0923 97e43c2f6080b97194e00d2619d9b775 412 PIRSF PIRSF000521 124 156 3.5 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0923 97e43c2f6080b97194e00d2619d9b775 412 SUPERFAMILY SSF53383 12 402 2.5E-133 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_2436 a431e48b1e13f5b348f1b2ef810d2795 433 Pfam PF02321 Outer membrane efflux protein 230 425 3.6E-15 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Theos_2436 a431e48b1e13f5b348f1b2ef810d2795 433 Pfam PF02321 Outer membrane efflux protein 37 203 1.6E-16 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Theos_2436 a431e48b1e13f5b348f1b2ef810d2795 433 SUPERFAMILY SSF56954 2 429 5.49E-50 T 14-10-2018 Theos_2436 a431e48b1e13f5b348f1b2ef810d2795 433 Gene3D G3DSA:1.20.1600.10 32 429 9.7E-57 T 14-10-2018 Theos_1100 63bc25885910eb87a57c7398e57ea6a3 350 Gene3D G3DSA:3.30.300.130 1 83 1.1E-18 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Theos_1100 63bc25885910eb87a57c7398e57ea6a3 350 SUPERFAMILY SSF117916 1 78 1.21E-20 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Theos_1100 63bc25885910eb87a57c7398e57ea6a3 350 ProSitePatterns PS01215 Mrp family signature. 199 215 - T 14-10-2018 IPR000808 Mrp, conserved site GO:0005524 Theos_1100 63bc25885910eb87a57c7398e57ea6a3 350 Pfam PF01883 Iron-sulfur cluster assembly protein 5 73 1.9E-20 T 14-10-2018 IPR002744 MIP18 family-like Theos_1100 63bc25885910eb87a57c7398e57ea6a3 350 Gene3D G3DSA:3.40.50.300 86 334 1.2E-85 T 14-10-2018 Theos_1100 63bc25885910eb87a57c7398e57ea6a3 350 Hamap MF_02040 Iron-sulfur cluster carrier protein. 87 336 37.923 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein Theos_1100 63bc25885910eb87a57c7398e57ea6a3 350 SUPERFAMILY SSF52540 93 340 1.15E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1100 63bc25885910eb87a57c7398e57ea6a3 350 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 92 335 1.8E-99 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 Theos_1000 40219192d23fb1048fc79180c1e46f70 436 Pfam PF00082 Subtilase family 194 424 4.9E-27 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Theos_1000 40219192d23fb1048fc79180c1e46f70 436 Gene3D G3DSA:3.40.50.200 176 435 4.3E-66 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_1000 40219192d23fb1048fc79180c1e46f70 436 PRINTS PR00723 Subtilisin serine protease family (S8) signature 229 242 2.9E-12 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_1000 40219192d23fb1048fc79180c1e46f70 436 PRINTS PR00723 Subtilisin serine protease family (S8) signature 194 213 2.9E-12 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_1000 40219192d23fb1048fc79180c1e46f70 436 PRINTS PR00723 Subtilisin serine protease family (S8) signature 379 395 2.9E-12 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_1000 40219192d23fb1048fc79180c1e46f70 436 SUPERFAMILY SSF52743 178 433 1.31E-63 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_1000 40219192d23fb1048fc79180c1e46f70 436 Gene3D G3DSA:2.60.40.10 28 99 2.4E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold Theos_1000 40219192d23fb1048fc79180c1e46f70 436 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 380 390 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site Theos_1135 46d5cde4daee1d33702631f5a3e2c03a 224 SUPERFAMILY SSF110296 31 213 4.97E-14 T 14-10-2018 Theos_0576 591c7e9f6d25ec7c8e617157112c4fc9 344 Gene3D G3DSA:3.30.70.1140 1 76 9.9E-20 T 14-10-2018 Theos_0576 591c7e9f6d25ec7c8e617157112c4fc9 344 SUPERFAMILY SSF51569 1 336 8.24E-108 T 14-10-2018 Theos_0576 591c7e9f6d25ec7c8e617157112c4fc9 344 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 72 328 1.8E-115 T 14-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Theos_0576 591c7e9f6d25ec7c8e617157112c4fc9 344 Pfam PF00793 DAHP synthetase I family 91 328 1.3E-71 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Theos_0576 591c7e9f6d25ec7c8e617157112c4fc9 344 Gene3D G3DSA:3.20.20.70 77 333 8.8E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0016 9f1b6597a7f4a67a6dfc7c6093ad19fc 247 PRINTS PR00474 Glutamate 5-kinase family signature 193 213 7.1E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_0016 9f1b6597a7f4a67a6dfc7c6093ad19fc 247 PRINTS PR00474 Glutamate 5-kinase family signature 19 33 7.1E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_0016 9f1b6597a7f4a67a6dfc7c6093ad19fc 247 PRINTS PR00474 Glutamate 5-kinase family signature 140 167 7.1E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_0016 9f1b6597a7f4a67a6dfc7c6093ad19fc 247 Gene3D G3DSA:3.40.1160.10 1 243 1.6E-59 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_0016 9f1b6597a7f4a67a6dfc7c6093ad19fc 247 Pfam PF00696 Amino acid kinase family 9 212 2.2E-30 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Theos_0016 9f1b6597a7f4a67a6dfc7c6093ad19fc 247 PIRSF PIRSF000728 1 239 2.1E-65 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_0016 9f1b6597a7f4a67a6dfc7c6093ad19fc 247 Hamap MF_00082 Acetylglutamate kinase [argB]. 1 235 39.257 T 14-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_0016 9f1b6597a7f4a67a6dfc7c6093ad19fc 247 SUPERFAMILY SSF53633 10 239 7.99E-50 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_0016 9f1b6597a7f4a67a6dfc7c6093ad19fc 247 TIGRFAM TIGR00761 argB: acetylglutamate kinase 22 217 7.0E-49 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 Pfam PF00232 Glycosyl hydrolase family 1 4 425 2.0E-136 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 331 339 - T 14-10-2018 IPR018120 Glycoside hydrolase family 1, active site Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 PRINTS PR00131 Glycosyl hydrolase family 1 signature 272 286 1.2E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 PRINTS PR00131 Glycosyl hydrolase family 1 signature 331 339 1.2E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 390 1.2E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 PRINTS PR00131 Glycosyl hydrolase family 1 signature 352 363 1.2E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 PRINTS PR00131 Glycosyl hydrolase family 1 signature 397 409 1.2E-23 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 SUPERFAMILY SSF51445 5 425 6.74E-154 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 Gene3D G3DSA:3.20.20.80 3 428 8.4E-161 T 14-10-2018 Theos_2285 0ff88e7da1da8ea8856d96d11921005a 431 TIGRFAM TIGR03356 BGL: beta-galactosidase 4 419 1.7E-170 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 Theos_0767 63e71c766d745d2c866a46d25244791b 333 SUPERFAMILY SSF88723 142 264 4.21E-21 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_0767 63e71c766d745d2c866a46d25244791b 333 SMART SM00670 140 244 2.1E-6 T 14-10-2018 IPR002716 PIN domain Theos_0767 63e71c766d745d2c866a46d25244791b 333 Gene3D G3DSA:3.40.50.1010 139 268 4.4E-43 T 14-10-2018 Theos_0509 936025528650a658ec9731003381c7f7 503 Gene3D G3DSA:3.90.76.10 30 178 2.9E-146 T 14-10-2018 Theos_0509 936025528650a658ec9731003381c7f7 503 Gene3D G3DSA:3.40.190.10 179 487 2.9E-146 T 14-10-2018 Theos_0509 936025528650a658ec9731003381c7f7 503 Gene3D G3DSA:3.10.105.10 253 477 2.9E-146 T 14-10-2018 Theos_0509 936025528650a658ec9731003381c7f7 503 SUPERFAMILY SSF53850 20 502 2.53E-142 T 14-10-2018 Theos_0509 936025528650a658ec9731003381c7f7 503 PIRSF PIRSF002741 14 502 1.4E-108 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Theos_0509 936025528650a658ec9731003381c7f7 503 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 63 421 8.8E-96 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 SUPERFAMILY SSF52540 3 603 3.06E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 Gene3D G3DSA:3.40.50.300 476 627 2.7E-20 T 14-10-2018 Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 Gene3D G3DSA:3.40.50.300 156 284 4.1E-27 T 14-10-2018 Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 Gene3D G3DSA:3.90.320.10 762 840 1.7E-7 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 Pfam PF13361 UvrD-like helicase C-terminal domain 264 393 7.3E-9 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 Pfam PF13245 AAA domain 5 244 1.1E-23 T 14-10-2018 Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 Pfam PF12705 PD-(D/E)XK nuclease superfamily 693 836 2.1E-7 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 Gene3D G3DSA:3.40.50.300 2 147 7.1E-21 T 14-10-2018 Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 SUPERFAMILY SSF52980 692 831 1.93E-8 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 Gene3D G3DSA:3.40.50.300 316 416 8.6E-19 T 14-10-2018 Theos_0356 72523abb8f8f2469f6e5a95dfe657d1a 854 Pfam PF13361 UvrD-like helicase C-terminal domain 491 600 3.1E-12 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Theos_1539 fe3983b7d1f69a7e10aae07b9ef09df6 346 SUPERFAMILY SSF50129 1 179 2.74E-52 T 14-10-2018 IPR011032 GroES-like superfamily Theos_1539 fe3983b7d1f69a7e10aae07b9ef09df6 346 SMART SM00829 8 343 3.2E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Theos_1539 fe3983b7d1f69a7e10aae07b9ef09df6 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 130 1.9E-30 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Theos_1539 fe3983b7d1f69a7e10aae07b9ef09df6 346 Gene3D G3DSA:3.90.180.10 14 334 4.5E-129 T 14-10-2018 Theos_1539 fe3983b7d1f69a7e10aae07b9ef09df6 346 Gene3D G3DSA:3.40.50.720 157 291 4.5E-129 T 14-10-2018 Theos_1539 fe3983b7d1f69a7e10aae07b9ef09df6 346 Pfam PF00107 Zinc-binding dehydrogenase 179 306 3.5E-22 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Theos_1539 fe3983b7d1f69a7e10aae07b9ef09df6 346 SUPERFAMILY SSF51735 141 311 8.12E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1539 fe3983b7d1f69a7e10aae07b9ef09df6 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 SUPERFAMILY SSF55681 96 421 1.18E-79 T 14-10-2018 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 6 422 1.4E-119 T 14-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 Gene3D G3DSA:2.40.50.140 1 92 3.7E-25 T 14-10-2018 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 Pfam PF00152 tRNA synthetases class II (D, K and N) 106 416 2.3E-81 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 SUPERFAMILY SSF50249 4 93 6.64E-21 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 Gene3D G3DSA:3.30.930.10 93 411 3.0E-122 T 14-10-2018 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 204 9.4E-22 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 377 391 9.4E-22 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 337 353 9.4E-22 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 175 187 9.4E-22 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 422 39.47 T 14-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_1657 446ddf8bd3c1c133ca82cb9835335031 422 Pfam PF01336 OB-fold nucleic acid binding domain 25 85 2.0E-7 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 Pfam PF06071 Protein of unknown function (DUF933) 284 367 2.2E-35 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 2 368 8.8E-130 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 Pfam PF01926 50S ribosome-binding GTPase 4 121 5.0E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 1 368 44.186 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 Gene3D G3DSA:3.10.20.30 47 362 1.3E-147 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 Gene3D G3DSA:1.10.150.300 126 204 1.3E-147 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 9.3E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 88 9.3E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 90 108 9.3E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 9.3E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 Gene3D G3DSA:3.40.50.300 4 285 1.3E-147 T 14-10-2018 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 SUPERFAMILY SSF52540 3 305 1.24E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 PIRSF PIRSF006641 1 368 3.4E-144 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Theos_1203 b340fd1a2ffcaba96fe1d6470a04fb91 368 SUPERFAMILY SSF81271 284 364 2.83E-33 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 SUPERFAMILY SSF55666 151 242 1.15E-29 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 SUPERFAMILY SSF54211 11 150 6.07E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Gene3D G3DSA:2.40.50.140 634 704 3.7E-25 T 14-10-2018 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Pfam PF00013 KH domain 570 625 2.5E-11 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 10 705 30.017 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Gene3D G3DSA:3.30.1370.10 563 633 1.9E-17 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Pfam PF01138 3' exoribonuclease family, domain 1 21 150 3.6E-19 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Pfam PF01138 3' exoribonuclease family, domain 1 336 469 1.4E-25 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Pfam PF03725 3' exoribonuclease family, domain 2 473 541 1.4E-6 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Pfam PF03725 3' exoribonuclease family, domain 2 153 216 2.9E-19 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 PIRSF PIRSF005499 8 713 2.8E-289 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Gene3D G3DSA:3.30.230.70 3 235 1.4E-79 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 SUPERFAMILY SSF54791 565 641 2.87E-14 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 18 702 1.9E-296 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 SMART SM00316 632 702 5.6E-26 T 14-10-2018 IPR022967 RNA-binding domain, S1 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 SUPERFAMILY SSF50249 620 699 2.0E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 SMART SM00322 565 629 4.3E-13 T 14-10-2018 IPR004087 K Homology domain GO:0003676 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Pfam PF00575 S1 RNA binding domain 631 699 9.0E-17 T 14-10-2018 IPR003029 S1 domain GO:0003676 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 SUPERFAMILY SSF46915 259 333 4.45E-8 T 14-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 SUPERFAMILY SSF55666 463 561 3.53E-28 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Gene3D G3DSA:3.30.230.70 247 562 7.4E-116 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 SUPERFAMILY SSF54211 310 481 7.09E-52 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_1503 88ce2c9b9b44584f1a90a5cb86cb916d 714 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 259 332 5.2E-7 T 14-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 TIGRFAM TIGR02082 metH: methionine synthase 46 1183 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Gene3D G3DSA:3.20.20.20 357 650 1.2E-91 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Pfam PF02310 B12 binding domain 751 865 8.9E-19 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 SUPERFAMILY SSF52242 746 874 5.49E-35 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 SUPERFAMILY SSF56507 895 1183 3.14E-80 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Pfam PF02574 Homocysteine S-methyltransferase 50 337 1.3E-64 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Gene3D G3DSA:1.10.1240.10 654 742 1.6E-30 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Gene3D G3DSA:3.20.20.330 38 346 1.7E-95 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 SUPERFAMILY SSF82282 40 411 9.81E-111 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 PIRSF PIRSF000381 34 1183 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Pfam PF00809 Pterin binding enzyme 372 605 8.8E-47 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Gene3D G3DSA:3.40.50.280 747 882 4.3E-41 T 14-10-2018 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Gene3D G3DSA:3.10.196.10 907 1183 2.6E-46 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 SUPERFAMILY SSF51717 369 637 4.58E-72 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 SUPERFAMILY SSF47644 662 743 5.1E-25 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Pfam PF02607 B12 binding domain 665 738 1.0E-26 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 965 1183 6.5E-37 T 14-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 SMART SM01018 662 745 6.5E-40 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1344 343ea53888b3a57cc8b341b79f7f982c 1183 Gene3D G3DSA:1.10.288.10 921 979 2.6E-46 T 14-10-2018 Theos_1991 4a93e796ffe445f3c76f863a4c29b677 329 SUPERFAMILY SSF52418 71 325 1.7E-82 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_1991 4a93e796ffe445f3c76f863a4c29b677 329 Pfam PF00591 Glycosyl transferase family, a/b domain 72 317 6.5E-82 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_1991 4a93e796ffe445f3c76f863a4c29b677 329 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 325 2.8E-108 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Theos_1991 4a93e796ffe445f3c76f863a4c29b677 329 Gene3D G3DSA:3.40.1030.10 68 328 1.2E-98 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_1991 4a93e796ffe445f3c76f863a4c29b677 329 SUPERFAMILY SSF47648 2 64 8.24E-16 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_1991 4a93e796ffe445f3c76f863a4c29b677 329 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 2 326 35.128 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Theos_1991 4a93e796ffe445f3c76f863a4c29b677 329 Pfam PF02885 Glycosyl transferase family, helical bundle domain 2 63 1.7E-16 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_1991 4a93e796ffe445f3c76f863a4c29b677 329 Gene3D G3DSA:1.20.970.10 1 67 9.1E-22 T 14-10-2018 Theos_1001 2de037433aea9358359af5e3795572e6 569 SUPERFAMILY SSF48452 335 467 3.62E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1001 2de037433aea9358359af5e3795572e6 569 Gene3D G3DSA:1.25.40.10 485 566 3.5E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1001 2de037433aea9358359af5e3795572e6 569 Gene3D G3DSA:1.25.40.10 405 484 2.9E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1001 2de037433aea9358359af5e3795572e6 569 Pfam PF13424 Tetratricopeptide repeat 450 520 9.0E-12 T 14-10-2018 Theos_1001 2de037433aea9358359af5e3795572e6 569 Gene3D G3DSA:1.25.40.10 295 404 6.4E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1001 2de037433aea9358359af5e3795572e6 569 Pfam PF13432 Tetratricopeptide repeat 342 398 0.012 T 14-10-2018 Theos_1001 2de037433aea9358359af5e3795572e6 569 SUPERFAMILY SSF48452 251 363 8.43E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1001 2de037433aea9358359af5e3795572e6 569 SUPERFAMILY SSF48452 428 558 4.74E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1001 2de037433aea9358359af5e3795572e6 569 SMART SM00028 411 443 87.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1001 2de037433aea9358359af5e3795572e6 569 SMART SM00028 448 481 0.04 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1001 2de037433aea9358359af5e3795572e6 569 SMART SM00028 488 521 1.2E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 Gene3D G3DSA:3.40.50.300 408 582 1.2E-49 T 14-10-2018 Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 641 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 Gene3D G3DSA:3.40.50.300 263 407 5.8E-53 T 14-10-2018 Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 Gene3D G3DSA:3.40.50.300 1 231 2.4E-70 T 14-10-2018 Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 Pfam PF02151 UvrB/uvrC motif 609 643 8.9E-9 T 14-10-2018 IPR001943 UVR domain GO:0005515 Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 SMART SM00490 453 539 1.8E-17 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 Pfam PF00271 Helicase conserved C-terminal domain 428 538 1.2E-17 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 Pfam PF12344 Ultra-violet resistance protein B 545 586 1.4E-20 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 Hamap MF_00204 UvrABC system protein B [uvrB]. 1 644 42.337 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 SUPERFAMILY SSF46600 604 646 2.09E-10 T 14-10-2018 IPR036876 UVR domain superfamily Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 Pfam PF04851 Type III restriction enzyme, res subunit 12 131 2.8E-11 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 Gene3D G3DSA:4.10.860.10 596 646 1.6E-6 T 14-10-2018 Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 SMART SM00487 5 418 6.8E-28 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 SUPERFAMILY SSF52540 6 408 1.41E-124 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0169 daaa253400cd41a4dbbb4824b2d89c0b 663 SUPERFAMILY SSF52540 33 565 1.05E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0315 0d24b92ecd160ef7078f78ef223f318f 203 SUPERFAMILY SSF52972 1 189 8.11E-67 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Theos_0315 0d24b92ecd160ef7078f78ef223f318f 203 Pfam PF01725 Ham1 family 3 188 6.0E-56 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 Theos_0315 0d24b92ecd160ef7078f78ef223f318f 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 189 2.0E-55 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 Theos_0315 0d24b92ecd160ef7078f78ef223f318f 203 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 192 46.616 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 Theos_0315 0d24b92ecd160ef7078f78ef223f318f 203 Gene3D G3DSA:3.90.950.10 1 192 2.9E-71 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Theos_0175 ac331a04a09771a4ff8571fee80dc03a 206 Gene3D G3DSA:1.10.150.240 17 82 3.5E-51 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Theos_0175 ac331a04a09771a4ff8571fee80dc03a 206 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 179 9.2E-27 T 14-10-2018 Theos_0175 ac331a04a09771a4ff8571fee80dc03a 206 SUPERFAMILY SSF56784 2 204 1.65E-53 T 14-10-2018 IPR036412 HAD-like superfamily Theos_0175 ac331a04a09771a4ff8571fee80dc03a 206 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 70 178 1.3E-16 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0175 ac331a04a09771a4ff8571fee80dc03a 206 Gene3D G3DSA:3.40.50.1000 3 196 3.5E-51 T 14-10-2018 IPR023214 HAD superfamily Theos_0175 ac331a04a09771a4ff8571fee80dc03a 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 162 3.3E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0175 ac331a04a09771a4ff8571fee80dc03a 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 3.3E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0175 ac331a04a09771a4ff8571fee80dc03a 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 95 108 3.3E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_2198 fc41306410b6d8a675dc4d7b243074ed 175 SUPERFAMILY SSF50324 4 173 3.53E-62 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Theos_2198 fc41306410b6d8a675dc4d7b243074ed 175 Pfam PF00719 Inorganic pyrophosphatase 19 173 1.2E-53 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Theos_2198 fc41306410b6d8a675dc4d7b243074ed 175 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Theos_2198 fc41306410b6d8a675dc4d7b243074ed 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 174 36.526 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Theos_2198 fc41306410b6d8a675dc4d7b243074ed 175 Gene3D G3DSA:3.90.80.10 2 175 1.7E-71 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Theos_1441 969210f231df44cdd8172df56211c51c 581 SUPERFAMILY SSF55261 295 413 6.38E-33 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Theos_1441 969210f231df44cdd8172df56211c51c 581 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 578 34.005 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 Theos_1441 969210f231df44cdd8172df56211c51c 581 SUPERFAMILY SSF55681 105 578 3.94E-108 T 14-10-2018 Theos_1441 969210f231df44cdd8172df56211c51c 581 Gene3D G3DSA:3.30.1360.30 278 415 3.4E-189 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Theos_1441 969210f231df44cdd8172df56211c51c 581 Gene3D G3DSA:2.40.50.140 1 102 3.1E-31 T 14-10-2018 Theos_1441 969210f231df44cdd8172df56211c51c 581 SUPERFAMILY SSF50249 1 103 7.5E-29 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1441 969210f231df44cdd8172df56211c51c 581 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 579 4.1E-218 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 Theos_1441 969210f231df44cdd8172df56211c51c 581 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 551 3.0E-109 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1441 969210f231df44cdd8172df56211c51c 581 Pfam PF02938 GAD domain 317 400 1.7E-23 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 Theos_1441 969210f231df44cdd8172df56211c51c 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 512 526 1.4E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1441 969210f231df44cdd8172df56211c51c 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 213 226 1.4E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1441 969210f231df44cdd8172df56211c51c 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 468 484 1.4E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1441 969210f231df44cdd8172df56211c51c 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 208 1.4E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1441 969210f231df44cdd8172df56211c51c 581 Gene3D G3DSA:3.30.930.10 140 573 3.4E-189 T 14-10-2018 Theos_1441 969210f231df44cdd8172df56211c51c 581 Pfam PF01336 OB-fold nucleic acid binding domain 19 99 4.7E-14 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Theos_1704 3cb84a402fedc5f80812dec554d8fb14 596 Pfam PF00773 RNB domain 446 493 2.1E-12 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Theos_1704 3cb84a402fedc5f80812dec554d8fb14 596 Gene3D G3DSA:1.10.10.10 145 212 2.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1704 3cb84a402fedc5f80812dec554d8fb14 596 Pfam PF00773 RNB domain 221 432 1.0E-40 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Theos_1704 3cb84a402fedc5f80812dec554d8fb14 596 SUPERFAMILY SSF50249 537 594 4.11E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1704 3cb84a402fedc5f80812dec554d8fb14 596 SMART SM00955 221 494 2.7E-77 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Theos_1704 3cb84a402fedc5f80812dec554d8fb14 596 Gene3D G3DSA:2.40.50.140 537 596 6.3E-6 T 14-10-2018 Theos_1704 3cb84a402fedc5f80812dec554d8fb14 596 SUPERFAMILY SSF50249 172 535 1.14E-88 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0916 a0fcc39d0fd7a5730a618db8ade025a7 238 SUPERFAMILY SSF56317 1 236 2.22E-40 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Theos_0916 a0fcc39d0fd7a5730a618db8ade025a7 238 Pfam PF00795 Carbon-nitrogen hydrolase 3 222 6.2E-17 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Theos_0916 a0fcc39d0fd7a5730a618db8ade025a7 238 Gene3D G3DSA:3.60.110.10 1 237 1.8E-44 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Theos_0991 2e0bd767e5906c1a2a6b5f19f5d1121d 170 Gene3D G3DSA:3.10.20.520 2 64 5.1E-17 T 14-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B Theos_0991 2e0bd767e5906c1a2a6b5f19f5d1121d 170 Pfam PF06243 Phenylacetic acid degradation B 81 165 2.9E-9 T 14-10-2018 IPR009359 Phenylacetic acid degradation B Theos_0991 2e0bd767e5906c1a2a6b5f19f5d1121d 170 Pfam PF06243 Phenylacetic acid degradation B 5 68 4.4E-24 T 14-10-2018 IPR009359 Phenylacetic acid degradation B Theos_2260 baad3f261e9c1a94d06020a543a59f3c 477 Gene3D G3DSA:3.40.390.10 51 277 4.9E-66 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 Theos_2260 baad3f261e9c1a94d06020a543a59f3c 477 PRINTS PR00480 Astacin family signature 110 128 1.2E-24 T 14-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Theos_2260 baad3f261e9c1a94d06020a543a59f3c 477 PRINTS PR00480 Astacin family signature 187 204 1.2E-24 T 14-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Theos_2260 baad3f261e9c1a94d06020a543a59f3c 477 PRINTS PR00480 Astacin family signature 168 186 1.2E-24 T 14-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Theos_2260 baad3f261e9c1a94d06020a543a59f3c 477 PRINTS PR00480 Astacin family signature 262 275 1.2E-24 T 14-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Theos_2260 baad3f261e9c1a94d06020a543a59f3c 477 PRINTS PR00480 Astacin family signature 224 239 1.2E-24 T 14-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Theos_2260 baad3f261e9c1a94d06020a543a59f3c 477 SMART SM00235 85 229 1.7E-40 T 14-10-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 Theos_2260 baad3f261e9c1a94d06020a543a59f3c 477 Pfam PF01400 Astacin (Peptidase family M12A) 88 274 1.0E-54 T 14-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Theos_2260 baad3f261e9c1a94d06020a543a59f3c 477 SUPERFAMILY SSF55486 85 274 4.08E-52 T 14-10-2018 Theos_1283 20efc3ce1b54378c52790c6dc21d9c0c 406 Gene3D G3DSA:3.30.830.10 1 212 1.1E-75 T 14-10-2018 Theos_1283 20efc3ce1b54378c52790c6dc21d9c0c 406 SUPERFAMILY SSF63411 234 395 3.99E-27 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Theos_1283 20efc3ce1b54378c52790c6dc21d9c0c 406 Pfam PF05193 Peptidase M16 inactive domain 165 336 3.0E-21 T 14-10-2018 IPR007863 Peptidase M16, C-terminal Theos_1283 20efc3ce1b54378c52790c6dc21d9c0c 406 Gene3D G3DSA:3.30.830.10 224 404 2.3E-40 T 14-10-2018 Theos_1283 20efc3ce1b54378c52790c6dc21d9c0c 406 Pfam PF00675 Insulinase (Peptidase family M16) 13 158 1.0E-25 T 14-10-2018 IPR011765 Peptidase M16, N-terminal Theos_1283 20efc3ce1b54378c52790c6dc21d9c0c 406 SUPERFAMILY SSF63411 3 203 1.47E-50 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 Pfam PF01751 Toprim domain 416 532 2.3E-18 T 14-10-2018 IPR006171 TOPRIM domain Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 Gene3D G3DSA:3.40.50.670 395 634 1.7E-106 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 ProSitePatterns PS00177 DNA topoisomerase II signature. 419 427 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 Gene3D G3DSA:3.30.565.10 10 216 3.1E-83 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 172 1.6E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 SMART SM00433 32 628 0.0 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 SUPERFAMILY SSF54211 218 388 1.61E-47 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 193 206 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 588 600 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 357 371 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 217 239 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 309 325 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 604 620 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 178 193 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 3 13 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 371 391 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR01159 DNA gyrase subunit B signature 467 476 9.7E-50 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 SUPERFAMILY SSF55874 3 211 2.75E-65 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 SMART SM00387 28 173 2.2E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 Gene3D G3DSA:3.30.230.10 217 389 2.7E-61 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 Pfam PF00204 DNA gyrase B 218 387 2.1E-50 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 563 624 1.8E-29 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR00418 DNA topoisomerase II family signature 67 80 1.1E-69 T 14-10-2018 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR00418 DNA topoisomerase II family signature 506 523 1.1E-69 T 14-10-2018 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR00418 DNA topoisomerase II family signature 567 583 1.1E-69 T 14-10-2018 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR00418 DNA topoisomerase II family signature 32 47 1.1E-69 T 14-10-2018 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR00418 DNA topoisomerase II family signature 110 124 1.1E-69 T 14-10-2018 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR00418 DNA topoisomerase II family signature 488 504 1.1E-69 T 14-10-2018 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR00418 DNA topoisomerase II family signature 265 278 1.1E-69 T 14-10-2018 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR00418 DNA topoisomerase II family signature 417 431 1.1E-69 T 14-10-2018 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 PRINTS PR00418 DNA topoisomerase II family signature 526 538 1.1E-69 T 14-10-2018 Theos_1571 1b8a6825694ce45d583703cefa1542b5 634 SUPERFAMILY SSF56719 391 628 1.05E-87 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 430 32.592 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 6.2E-19 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 SUPERFAMILY SSF47446 295 418 4.84E-36 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 Gene3D G3DSA:1.20.120.140 5 303 4.3E-124 T 14-10-2018 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 Pfam PF00448 SRP54-type protein, GTPase domain 100 293 1.5E-68 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 SUPERFAMILY SSF52540 94 295 6.79E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 Gene3D G3DSA:1.10.260.30 320 430 2.6E-38 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 416 2.1E-162 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 Gene3D G3DSA:3.40.50.300 90 282 4.3E-124 T 14-10-2018 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 Pfam PF02978 Signal peptide binding domain 320 415 9.4E-30 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 SUPERFAMILY SSF47364 1 90 3.4E-24 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 SMART SM00962 98 293 1.9E-105 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 266 279 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 SMART SM00382 97 244 8.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0899 3cd93b88aaa7eaebba1c5a1b76ba56e0 431 SMART SM00963 1 86 5.1E-29 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_2310 9e8d18305e11c696f9c8fae2f4a97ac1 187 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 18 186 7.6E-64 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 Theos_2310 9e8d18305e11c696f9c8fae2f4a97ac1 187 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 16 187 6.3E-62 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 Theos_2310 9e8d18305e11c696f9c8fae2f4a97ac1 187 Gene3D G3DSA:3.40.50.300 8 187 1.3E-67 T 14-10-2018 Theos_2310 9e8d18305e11c696f9c8fae2f4a97ac1 187 SUPERFAMILY SSF52540 16 186 1.55E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2310 9e8d18305e11c696f9c8fae2f4a97ac1 187 PIRSF PIRSF015617 8 187 7.6E-67 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 Theos_1943 035a8b03f100e746adf0b5cebf2991a6 186 Gene3D G3DSA:3.40.50.1950 5 186 6.1E-71 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Theos_1943 035a8b03f100e746adf0b5cebf2991a6 186 Pfam PF02441 Flavoprotein 5 165 1.4E-23 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 Theos_1943 035a8b03f100e746adf0b5cebf2991a6 186 SUPERFAMILY SSF52507 5 186 1.57E-56 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Theos_1943 035a8b03f100e746adf0b5cebf2991a6 186 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 5 184 9.5E-58 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Theos_1943 035a8b03f100e746adf0b5cebf2991a6 186 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 4 186 34.497 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 SUPERFAMILY SSF52172 1 125 4.13E-25 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 1.4E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 1.4E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 1.4E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 192 5.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 Pfam PF00072 Response regulator receiver domain 3 108 1.5E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 Gene3D G3DSA:3.40.50.12740 1 198 8.5E-47 T 14-10-2018 Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 SMART SM00448 1 108 2.6E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 SUPERFAMILY SSF46894 130 197 1.73E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Theos_0753 4ca2a58e4c2b36595d8c2f7c538b3562 198 SMART SM00421 135 192 1.6E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 Gene3D G3DSA:3.40.50.300 278 581 1.1E-77 T 14-10-2018 Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 PIRSF PIRSF005814 1 742 7.6E-203 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 1 741 19.311 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 SMART SM00463 664 742 4.0E-19 T 14-10-2018 IPR002625 Smr domain Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 Gene3D G3DSA:3.30.1370.110 659 743 1.5E-24 T 14-10-2018 Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 SMART SM00533 8 296 5.5E-9 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 SUPERFAMILY SSF48334 20 272 4.19E-20 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 SMART SM00534 307 491 2.9E-71 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 Pfam PF01713 Smr domain 667 742 1.4E-19 T 14-10-2018 IPR002625 Smr domain Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 SUPERFAMILY SSF160443 666 742 2.75E-10 T 14-10-2018 IPR036063 Smr domain superfamily Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 TIGRFAM TIGR01069 mutS2: MutS2 family protein 3 742 1.2E-171 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 SUPERFAMILY SSF52540 284 491 1.78E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 388 404 - T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Theos_0391 390a7d08792c84e65cfff0e69f259eac 743 Pfam PF00488 MutS domain V 311 490 2.3E-37 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Theos_1700 8b3992a5db2fdb5e9dbbaa5f7fd9d097 390 Pfam PF00589 Phage integrase family 188 368 6.6E-32 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Theos_1700 8b3992a5db2fdb5e9dbbaa5f7fd9d097 390 SUPERFAMILY SSF56349 66 373 5.0E-71 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Theos_1700 8b3992a5db2fdb5e9dbbaa5f7fd9d097 390 Gene3D G3DSA:1.10.150.130 66 175 6.0E-23 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Theos_1700 8b3992a5db2fdb5e9dbbaa5f7fd9d097 390 Gene3D G3DSA:1.10.443.10 187 376 1.2E-49 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PIRSF PIRSF000724 1 389 6.0E-133 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 Gene3D G3DSA:3.40.50.1260 1 177 1.3E-71 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 5.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PRINTS PR00477 Phosphoglycerate kinase family signature 164 186 5.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PRINTS PR00477 Phosphoglycerate kinase family signature 134 156 5.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PRINTS PR00477 Phosphoglycerate kinase family signature 343 354 5.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 5.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PRINTS PR00477 Phosphoglycerate kinase family signature 366 383 5.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PRINTS PR00477 Phosphoglycerate kinase family signature 106 121 5.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PRINTS PR00477 Phosphoglycerate kinase family signature 187 206 5.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 PRINTS PR00477 Phosphoglycerate kinase family signature 309 334 5.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 SUPERFAMILY SSF53748 2 389 4.59E-144 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 14-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 389 39.766 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 Pfam PF00162 Phosphoglycerate kinase 5 378 1.4E-143 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0920 08bd7a80131d7450973009db7111f9a5 389 Gene3D G3DSA:3.40.50.1260 178 389 2.7E-89 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_1619 1afddd587224b78ee571f1141d4c4261 264 PIRSF PIRSF038455 3 264 2.1E-69 T 14-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 Theos_1619 1afddd587224b78ee571f1141d4c4261 264 SUPERFAMILY SSF46626 41 145 1.2E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1619 1afddd587224b78ee571f1141d4c4261 264 Gene3D G3DSA:1.10.760.10 138 255 3.8E-29 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1619 1afddd587224b78ee571f1141d4c4261 264 Gene3D G3DSA:1.10.760.10 51 137 1.6E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1619 1afddd587224b78ee571f1141d4c4261 264 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 49 255 2.0E-68 T 14-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 Theos_1619 1afddd587224b78ee571f1141d4c4261 264 SUPERFAMILY SSF46626 150 248 2.36E-28 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Pfam PF04998 RNA polymerase Rpb1, domain 5 1306 1430 2.5E-13 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:2.40.50.410 399 456 1.1E-35 T 14-10-2018 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:2.40.50.100 1270 1331 1.5E-71 T 14-10-2018 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Pfam PF05000 RNA polymerase Rpb1, domain 4 985 1051 6.4E-15 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:1.10.150.390 1432 1495 7.6E-31 T 14-10-2018 Theos_0186 64cfa6101205182950eefa31666932d1 1524 SMART SM00663 511 794 8.5E-165 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Pfam PF04983 RNA polymerase Rpb1, domain 3 769 954 1.4E-28 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:1.10.40.90 651 696 1.6E-23 T 14-10-2018 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Pfam PF04997 RNA polymerase Rpb1, domain 1 482 619 8.6E-46 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Pfam PF04997 RNA polymerase Rpb1, domain 1 2 160 7.5E-34 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:2.40.50.410 147 211 1.5E-33 T 14-10-2018 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:2.40.50.100 247 309 6.2E-15 T 14-10-2018 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:1.10.274.100 770 951 6.6E-62 T 14-10-2018 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:1.10.132.30 952 1089 2.0E-61 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 1 1493 18.025 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Pfam PF04998 RNA polymerase Rpb1, domain 5 1065 1285 3.6E-42 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Pfam PF00623 RNA polymerase Rpb1, domain 2 621 763 8.9E-36 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:1.10.1790.20 1254 1430 1.5E-71 T 14-10-2018 Theos_0186 64cfa6101205182950eefa31666932d1 1524 Gene3D G3DSA:3.90.105.30 1116 1190 7.6E-42 T 14-10-2018 Theos_0186 64cfa6101205182950eefa31666932d1 1524 SUPERFAMILY SSF64484 3 1486 0.0 T 14-10-2018 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 Gene3D G3DSA:3.40.50.20 551 658 4.2E-47 T 14-10-2018 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 835 842 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 543 1.6E-38 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 Gene3D G3DSA:3.30.470.20 662 933 3.7E-100 T 14-10-2018 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.7E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 3.7E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.7E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.7E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 386 404 3.7E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.7E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.7E-65 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 4 947 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 872 2.9E-33 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.4E-67 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 SUPERFAMILY SSF48108 402 550 3.53E-46 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 SMART SM01096 423 543 6.4E-65 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 SUPERFAMILY SSF52440 553 670 1.58E-48 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Theos_1352 5d585443ead01e296c0a3953dc755977 1028 Gene3D G3DSA:1.10.1030.10 408 549 2.8E-41 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 SUPERFAMILY SSF56059 669 931 2.47E-89 T 14-10-2018 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 Gene3D G3DSA:3.40.50.20 1 116 1.0E-44 T 14-10-2018 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 SUPERFAMILY SSF56059 128 407 3.18E-103 T 14-10-2018 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1012 12.328 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 Gene3D G3DSA:3.30.470.20 119 407 3.1E-120 T 14-10-2018 Theos_1352 5d585443ead01e296c0a3953dc755977 1028 SUPERFAMILY SSF52440 1 127 1.73E-45 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Theos_1352 5d585443ead01e296c0a3953dc755977 1028 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 143 161 1.4E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 226 243 1.4E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 170 186 1.4E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 106 119 1.4E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 266 281 1.4E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 Gene3D G3DSA:3.40.50.720 2 323 1.0E-154 T 14-10-2018 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 2 321 1.8E-131 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 SUPERFAMILY SSF51735 1 165 7.54E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0919 d43813dae63512ac9855231d12f28bf7 331 SMART SM00846 1 149 1.2E-90 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 154 309 6.4E-65 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 SUPERFAMILY SSF55347 149 310 2.44E-66 T 14-10-2018 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 PIRSF PIRSF000149 1 330 5.2E-125 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 Gene3D G3DSA:3.30.360.10 148 311 1.0E-154 T 14-10-2018 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1 99 3.1E-35 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0919 d43813dae63512ac9855231d12f28bf7 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 147 154 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 151 8.2E-37 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 SUPERFAMILY SSF51735 1 169 4.26E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 171 308 8.2E-47 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 229 246 1.3E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 164 188 1.3E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 189 213 1.3E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 5 22 1.3E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 55 82 1.3E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 Gene3D G3DSA:3.40.50.720 1 179 1.9E-48 T 14-10-2018 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 Gene3D G3DSA:1.10.1040.10 180 321 1.4E-46 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 PIRSF PIRSF000114 1 321 7.5E-84 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 311 32.172 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Theos_0009 543031d4d2e83cc73217e0ae24d4a26c 321 SUPERFAMILY SSF48179 171 320 4.59E-48 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Theos_0237 a27a4feaaeb9fa374b980a0a4f1bdd16 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 144 156 1.8E-16 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Theos_0237 a27a4feaaeb9fa374b980a0a4f1bdd16 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 62 77 1.8E-16 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Theos_0237 a27a4feaaeb9fa374b980a0a4f1bdd16 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 157 172 1.8E-16 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Theos_0237 a27a4feaaeb9fa374b980a0a4f1bdd16 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 88 100 1.8E-16 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Theos_0237 a27a4feaaeb9fa374b980a0a4f1bdd16 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 1.8E-16 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Theos_0237 a27a4feaaeb9fa374b980a0a4f1bdd16 199 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 49 193 6.9E-41 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Theos_0237 a27a4feaaeb9fa374b980a0a4f1bdd16 199 Gene3D G3DSA:2.40.100.10 43 199 1.6E-50 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Theos_0237 a27a4feaaeb9fa374b980a0a4f1bdd16 199 SUPERFAMILY SSF50891 48 196 1.9E-49 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Theos_0643 283c688299f885d80e2568a0b1bcd934 202 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 2 198 1.3E-58 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 Theos_0643 283c688299f885d80e2568a0b1bcd934 202 Pfam PF01914 MarC family integral membrane protein 2 201 4.1E-60 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 SUPERFAMILY SSF53738 10 217 2.83E-44 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 Gene3D G3DSA:3.40.120.10 301 422 3.7E-36 T 14-10-2018 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 SUPERFAMILY SSF53738 287 427 1.77E-31 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 Gene3D G3DSA:3.30.310.50 423 517 1.1E-22 T 14-10-2018 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 SUPERFAMILY SSF53738 191 299 4.83E-11 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 24 163 1.7E-30 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 459 513 2.5E-11 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 Gene3D G3DSA:3.40.120.10 1 202 9.5E-71 T 14-10-2018 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 124 133 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 193 299 2.1E-16 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 302 419 1.1E-26 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 SUPERFAMILY SSF55957 413 516 3.66E-19 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2164 0e9594049e6f9512f2c52b1a88f63821 517 Gene3D G3DSA:3.40.120.10 203 300 1.8E-44 T 14-10-2018 Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 Gene3D G3DSA:3.20.20.450 306 538 3.0E-50 T 14-10-2018 IPR035919 EAL domain superfamily Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 Gene3D G3DSA:3.30.70.270 128 289 7.3E-43 T 14-10-2018 Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 131 286 3.8E-30 T 14-10-2018 IPR000160 GGDEF domain Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 SUPERFAMILY SSF55073 138 286 7.69E-38 T 14-10-2018 IPR029787 Nucleotide cyclase Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 SUPERFAMILY SSF55785 13 120 1.15E-26 T 14-10-2018 IPR035965 PAS domain superfamily Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 SMART SM00052 296 536 2.8E-32 T 14-10-2018 IPR001633 EAL domain Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 SMART SM00086 80 122 0.0044 T 14-10-2018 IPR001610 PAC motif Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 121 3.1E-17 T 14-10-2018 IPR000014 PAS domain Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 Pfam PF00563 EAL domain 309 531 2.2E-42 T 14-10-2018 IPR001633 EAL domain Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 Pfam PF13426 PAS domain 20 120 1.3E-12 T 14-10-2018 IPR000014 PAS domain Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 SMART SM00267 122 293 4.7E-35 T 14-10-2018 IPR000160 GGDEF domain Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 Gene3D G3DSA:3.30.450.20 15 118 1.2E-27 T 14-10-2018 Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 SMART SM00091 8 74 9.7E-7 T 14-10-2018 IPR000014 PAS domain Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 Pfam PF00990 Diguanylate cyclase, GGDEF domain 133 286 1.5E-34 T 14-10-2018 IPR000160 GGDEF domain Theos_2426 7d0d156f8db8f71d48dd20036943d4e8 540 SUPERFAMILY SSF141868 307 535 1.7E-48 T 14-10-2018 IPR035919 EAL domain superfamily Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 SUPERFAMILY SSF48019 244 296 6.23E-5 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 Gene3D G3DSA:3.40.50.300 11 174 8.4E-96 T 14-10-2018 Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 39 57 4.2E-6 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 121 139 4.2E-6 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 227 294 7.9E-7 T 14-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 293 9.8E-110 T 14-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 Pfam PF13177 DNA polymerase III, delta subunit 18 175 8.8E-44 T 14-10-2018 Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 Gene3D G3DSA:1.10.8.60 6 233 8.4E-96 T 14-10-2018 Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 SUPERFAMILY SSF52540 30 218 4.64E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 SMART SM00382 35 330 9.9E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0014 8bd6b45353ad353cc382c97ed599084b 531 Gene3D G3DSA:1.10.40.100 489 531 1.2E-20 T 14-10-2018 Theos_1085 47408b9425685b0368ddc0235ea165fa 342 SUPERFAMILY SSF81345 7 338 1.57E-77 T 14-10-2018 IPR037294 ABC transporter, BtuC-like Theos_1085 47408b9425685b0368ddc0235ea165fa 342 Gene3D G3DSA:1.10.3470.10 10 342 8.6E-91 T 14-10-2018 IPR037294 ABC transporter, BtuC-like Theos_1085 47408b9425685b0368ddc0235ea165fa 342 Pfam PF01032 FecCD transport family 21 337 2.4E-84 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Theos_0287 cd112b72989afc253475cab4319e7082 122 SMART SM01374 1 122 2.8E-88 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Theos_0287 cd112b72989afc253475cab4319e7082 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0287 cd112b72989afc253475cab4319e7082 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.5E-57 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Theos_0287 cd112b72989afc253475cab4319e7082 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.21 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Theos_0287 cd112b72989afc253475cab4319e7082 122 SUPERFAMILY SSF50193 1 122 1.44E-53 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Theos_0287 cd112b72989afc253475cab4319e7082 122 Gene3D G3DSA:2.40.150.20 1 122 5.0E-57 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Theos_0287 cd112b72989afc253475cab4319e7082 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.2E-59 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 ProSitePatterns PS00483 Dihydroorotase signature 2. 305 316 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 SUPERFAMILY SSF51338 2 424 1.3E-18 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 424 9.8E-113 T 14-10-2018 Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 ProSitePatterns PS00482 Dihydroorotase signature 1. 53 61 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 Gene3D G3DSA:2.30.40.10 1 53 8.5E-11 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 Gene3D G3DSA:2.30.40.10 367 427 1.8E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 SUPERFAMILY SSF51556 50 368 6.81E-95 T 14-10-2018 IPR032466 Metal-dependent hydrolase Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 425 42.382 T 14-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 Pfam PF01979 Amidohydrolase family 47 422 6.6E-19 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Theos_0551 66af25d4e54d27ee8f78006db338e26f 427 Gene3D G3DSA:3.20.20.140 54 366 3.3E-126 T 14-10-2018 Theos_1749 af3d8ebeab29e339182108d6a1772a1f 367 SUPERFAMILY SSF103473 3 363 1.83E-30 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1749 af3d8ebeab29e339182108d6a1772a1f 367 Gene3D G3DSA:1.20.1250.20 186 367 1.6E-11 T 14-10-2018 Theos_1749 af3d8ebeab29e339182108d6a1772a1f 367 Gene3D G3DSA:1.20.1250.20 2 175 4.9E-14 T 14-10-2018 Theos_1749 af3d8ebeab29e339182108d6a1772a1f 367 Pfam PF07690 Major Facilitator Superfamily 5 166 2.8E-8 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_1557 c056823b1bdcdc757432b8b4e23386e9 260 Gene3D G3DSA:3.40.630.30 4 144 1.4E-10 T 14-10-2018 Theos_1557 c056823b1bdcdc757432b8b4e23386e9 260 Pfam PF00583 Acetyltransferase (GNAT) family 24 115 1.5E-5 T 14-10-2018 IPR000182 GNAT domain Theos_1557 c056823b1bdcdc757432b8b4e23386e9 260 SUPERFAMILY SSF55729 4 140 2.44E-12 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_1088 70ac01e6b6ea6adbc147fb7475326c07 411 Pfam PF01547 Bacterial extracellular solute-binding protein 33 325 1.3E-27 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_1088 70ac01e6b6ea6adbc147fb7475326c07 411 Gene3D G3DSA:3.40.190.10 24 366 9.7E-160 T 14-10-2018 Theos_1088 70ac01e6b6ea6adbc147fb7475326c07 411 SUPERFAMILY SSF53850 18 408 1.71E-61 T 14-10-2018 Theos_1088 70ac01e6b6ea6adbc147fb7475326c07 411 Gene3D G3DSA:3.40.190.10 141 389 9.7E-160 T 14-10-2018 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 Gene3D G3DSA:3.30.540.10 5 142 2.4E-38 T 14-10-2018 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 Gene3D G3DSA:3.40.190.80 144 264 9.2E-37 T 14-10-2018 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 4.8E-49 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 4.8E-49 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 43 63 4.8E-49 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 65 81 4.8E-49 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 4.8E-49 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 179 200 4.8E-49 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 SUPERFAMILY SSF56655 7 260 1.44E-75 T 14-10-2018 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 Theos_0367 398414de76d4bf28e1e7681f5dc216c6 265 Pfam PF00459 Inositol monophosphatase family 12 260 1.1E-61 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Theos_0430 2744f50ee4e0c490fbfff0ddb4b8588f 123 Gene3D G3DSA:3.90.470.20 1 118 5.7E-26 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Theos_0430 2744f50ee4e0c490fbfff0ddb4b8588f 123 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 73 4.0E-11 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Theos_0430 2744f50ee4e0c490fbfff0ddb4b8588f 123 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 116 1.0E-11 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Theos_0430 2744f50ee4e0c490fbfff0ddb4b8588f 123 SUPERFAMILY SSF56214 1 116 1.96E-16 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Theos_0430 2744f50ee4e0c490fbfff0ddb4b8588f 123 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 119 17.852 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 Gene3D G3DSA:1.10.3210.10 361 519 3.9E-25 T 14-10-2018 Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 Gene3D G3DSA:3.30.1370.10 261 349 8.4E-9 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 Pfam PF01966 HD domain 384 475 7.0E-19 T 14-10-2018 IPR006674 HD domain Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 SMART SM00322 255 322 1.7E-6 T 14-10-2018 IPR004087 K Homology domain GO:0003676 Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 Pfam PF12072 Domain of unknown function (DUF3552) 128 251 2.5E-16 T 14-10-2018 IPR022711 Ribonuclease Y, N-terminal Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 TIGRFAM TIGR00277 HDIG: HDIG domain 379 454 2.3E-24 T 14-10-2018 IPR006675 HDIG domain Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 Hamap MF_00335 Ribonuclease Y [rny]. 1 567 24.656 T 14-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 120 567 8.3E-192 T 14-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 SUPERFAMILY SSF109604 372 495 1.12E-28 T 14-10-2018 Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 SUPERFAMILY SSF54791 260 350 5.13E-15 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 Pfam PF00013 KH domain 260 317 1.0E-5 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 Theos_0181 7cac535ae631cb958d2ce00fde2097d6 567 SMART SM00471 379 485 2.4E-13 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 118 147 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SUPERFAMILY SSF56091 2 317 3.78E-117 T 14-10-2018 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Gene3D G3DSA:3.30.1490.70 84 313 1.8E-92 T 14-10-2018 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Gene3D G3DSA:2.40.50.140 320 406 1.9E-31 T 14-10-2018 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 408 432 9.7E-6 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SMART SM00292 588 664 2.8E-16 T 14-10-2018 IPR001357 BRCT domain Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SMART SM00532 5 446 4.5E-288 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Gene3D G3DSA:3.30.470.30 122 253 1.8E-92 T 14-10-2018 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Gene3D G3DSA:1.10.150.20 430 502 2.6E-31 T 14-10-2018 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Gene3D G3DSA:1.10.150.20 503 584 3.9E-27 T 14-10-2018 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 332 347 - T 14-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SUPERFAMILY SSF47781 405 581 3.71E-62 T 14-10-2018 IPR010994 RuvA domain 2-like Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SMART SM00278 510 529 85.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SMART SM00278 478 497 1.7 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SMART SM00278 444 463 1.2 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SMART SM00278 542 561 0.89 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Pfam PF12826 Helix-hairpin-helix motif 508 571 1.5E-18 T 14-10-2018 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Pfam PF14520 Helix-hairpin-helix domain 444 498 1.5E-8 T 14-10-2018 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SUPERFAMILY SSF50249 318 401 5.82E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Hamap MF_01588 DNA ligase [ligA]. 4 661 50.907 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Gene3D G3DSA:1.10.287.610 1 76 1.6E-33 T 14-10-2018 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 SUPERFAMILY SSF52113 586 665 1.41E-21 T 14-10-2018 IPR036420 BRCT domain superfamily Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 657 2.4E-261 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 322 398 7.3E-32 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 PIRSF PIRSF001604 1 665 5.2E-244 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 589 657 3.0E-13 T 14-10-2018 IPR001357 BRCT domain Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Gene3D G3DSA:3.40.50.10190 587 668 3.2E-28 T 14-10-2018 IPR036420 BRCT domain superfamily Theos_0615 32bde7fbc273ad7e179403704d89a2e4 670 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 319 2.9E-131 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 Theos_1306 f50c37423c57ce963275dbd38c41fbf8 363 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 231 236 - T 14-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 Theos_1306 f50c37423c57ce963275dbd38c41fbf8 363 Pfam PF01555 DNA methylase 13 71 1.4E-9 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 Theos_1306 f50c37423c57ce963275dbd38c41fbf8 363 Gene3D G3DSA:3.40.50.150 203 330 1.3E-6 T 14-10-2018 Theos_1306 f50c37423c57ce963275dbd38c41fbf8 363 Gene3D G3DSA:3.40.50.150 4 93 1.9E-12 T 14-10-2018 Theos_1306 f50c37423c57ce963275dbd38c41fbf8 363 SUPERFAMILY SSF53335 14 77 5.57E-15 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1306 f50c37423c57ce963275dbd38c41fbf8 363 SUPERFAMILY SSF53335 31 243 5.47E-8 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1306 f50c37423c57ce963275dbd38c41fbf8 363 SUPERFAMILY SSF53335 209 324 9.42E-6 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1498 daf94f017e6d9d51b66697ae408e9f4d 167 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 92 160 2.6E-9 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1498 daf94f017e6d9d51b66697ae408e9f4d 167 SUPERFAMILY SSF81464 2 39 2.03E-14 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1498 daf94f017e6d9d51b66697ae408e9f4d 167 SUPERFAMILY SSF49503 40 166 3.54E-34 T 14-10-2018 IPR008972 Cupredoxin Theos_1498 daf94f017e6d9d51b66697ae408e9f4d 167 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 111 159 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1498 daf94f017e6d9d51b66697ae408e9f4d 167 Gene3D G3DSA:2.60.40.420 55 166 3.5E-30 T 14-10-2018 IPR008972 Cupredoxin Theos_1498 daf94f017e6d9d51b66697ae408e9f4d 167 Pfam PF09125 Cytochrome C oxidase subunit II, transmembrane 2 39 5.5E-19 T 14-10-2018 IPR015209 Cytochrome C oxidase subunit IIa, transmembrane domain KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Theos_1498 daf94f017e6d9d51b66697ae408e9f4d 167 Gene3D G3DSA:1.20.1070.10 1 45 2.9E-21 T 14-10-2018 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 SUPERFAMILY SSF110921 393 497 1.57E-22 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 SUPERFAMILY SSF51569 1 291 1.61E-96 T 14-10-2018 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 509 40.831 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 Gene3D G3DSA:3.20.20.70 2 276 1.1E-107 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 Pfam PF08502 LeuA allosteric (dimerisation) domain 372 498 2.7E-30 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 Gene3D G3DSA:3.30.160.270 394 500 8.7E-9 T 14-10-2018 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 5 495 9.5E-205 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 Gene3D G3DSA:1.10.238.260 280 393 1.4E-35 T 14-10-2018 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 Pfam PF00682 HMGL-like 5 273 2.5E-92 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Theos_1228 24258c60ebe1a4aa66bae987eb1ce935 518 SMART SM00917 370 500 1.3E-33 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_2210 fc43db1ace67cd10d7dec03b90f4bdca 325 Gene3D G3DSA:3.40.190.150 31 316 7.0E-75 T 14-10-2018 Theos_2210 fc43db1ace67cd10d7dec03b90f4bdca 325 Gene3D G3DSA:3.40.190.10 126 251 7.0E-75 T 14-10-2018 Theos_2210 fc43db1ace67cd10d7dec03b90f4bdca 325 PIRSF PIRSF017082 2 324 9.5E-75 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 Theos_2210 fc43db1ace67cd10d7dec03b90f4bdca 325 SUPERFAMILY SSF53850 32 280 5.43E-11 T 14-10-2018 Theos_2210 fc43db1ace67cd10d7dec03b90f4bdca 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 3.9E-43 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Gene3D G3DSA:3.30.70.380 686 777 1.4E-30 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 SUPERFAMILY SSF50249 43 146 4.16E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Gene3D G3DSA:3.30.930.10 486 674 2.6E-52 T 14-10-2018 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 SUPERFAMILY SSF55681 462 671 2.78E-41 T 14-10-2018 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 771 39.392 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 SMART SM00874 399 466 2.0E-26 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Gene3D G3DSA:3.50.40.10 186 398 5.7E-81 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 SMART SM00873 207 383 1.6E-78 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Gene3D G3DSA:3.30.56.10 1 177 2.3E-54 T 14-10-2018 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 SMART SM00896 684 776 5.3E-36 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Pfam PF03483 B3/4 domain 208 383 1.5E-58 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Pfam PF03147 Ferredoxin-fold anticodon binding domain 684 771 3.7E-24 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 SUPERFAMILY SSF46955 1 178 1.1E-10 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 SUPERFAMILY SSF46955 401 470 1.1E-15 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Gene3D G3DSA:3.30.56.10 399 471 8.0E-26 T 14-10-2018 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Gene3D G3DSA:2.40.50.140 38 151 2.3E-54 T 14-10-2018 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Pfam PF03484 tRNA synthetase B5 domain 403 466 7.9E-18 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 SUPERFAMILY SSF54991 679 770 3.14E-26 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 SUPERFAMILY SSF56037 194 391 1.6E-64 T 14-10-2018 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 Pfam PF01588 Putative tRNA binding domain 45 141 8.4E-8 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 Theos_2193 ce2d86ad2485155c776711f8389d4f02 777 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 770 7.7E-186 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Theos_1997 04e6e9c8b1f63c705a655e45f78d5b02 204 Gene3D G3DSA:3.60.15.10 5 201 6.8E-38 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1997 04e6e9c8b1f63c705a655e45f78d5b02 204 SMART SM00849 10 186 7.0E-28 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_1997 04e6e9c8b1f63c705a655e45f78d5b02 204 Pfam PF00753 Metallo-beta-lactamase superfamily 9 186 1.1E-27 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_1997 04e6e9c8b1f63c705a655e45f78d5b02 204 SUPERFAMILY SSF56281 9 191 7.21E-41 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1944 7759e1e5b7f6a6117d7ee9ead9576e8f 125 Gene3D G3DSA:3.30.1390.10 56 125 2.9E-27 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Theos_1944 7759e1e5b7f6a6117d7ee9ead9576e8f 125 SUPERFAMILY SSF54736 55 125 1.5E-22 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Theos_1944 7759e1e5b7f6a6117d7ee9ead9576e8f 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 125 7.9E-26 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1944 7759e1e5b7f6a6117d7ee9ead9576e8f 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 5.9E-41 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1944 7759e1e5b7f6a6117d7ee9ead9576e8f 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 125 2.0E-14 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1944 7759e1e5b7f6a6117d7ee9ead9576e8f 125 Gene3D G3DSA:1.20.5.710 3 55 6.1E-17 T 14-10-2018 Theos_1944 7759e1e5b7f6a6117d7ee9ead9576e8f 125 SUPERFAMILY SSF48300 4 62 5.23E-14 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1944 7759e1e5b7f6a6117d7ee9ead9576e8f 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 125 23.298 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1944 7759e1e5b7f6a6117d7ee9ead9576e8f 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 1.4E-16 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0499 68aa30ad8a9b77067b5f44d5838e3c35 290 Gene3D G3DSA:3.40.50.10490 142 274 1.5E-61 T 14-10-2018 Theos_0499 68aa30ad8a9b77067b5f44d5838e3c35 290 SUPERFAMILY SSF53697 5 283 4.45E-53 T 14-10-2018 Theos_0499 68aa30ad8a9b77067b5f44d5838e3c35 290 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 149 288 1.3E-24 T 14-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 Theos_0499 68aa30ad8a9b77067b5f44d5838e3c35 290 Gene3D G3DSA:3.40.50.10920 16 141 6.0E-54 T 14-10-2018 Theos_2126 5d180da3ddc29bdba9b07a451eebd0b9 450 SUPERFAMILY SSF52467 276 449 5.2E-70 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Theos_2126 5d180da3ddc29bdba9b07a451eebd0b9 450 Pfam PF02233 NAD(P) transhydrogenase beta subunit 5 445 5.0E-175 T 14-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 Theos_2126 5d180da3ddc29bdba9b07a451eebd0b9 450 Gene3D G3DSA:3.40.50.1220 266 450 9.8E-86 T 14-10-2018 Theos_2126 5d180da3ddc29bdba9b07a451eebd0b9 450 PIRSF PIRSF000204 1 449 6.4E-163 T 14-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 Theos_1217 ed18b9a5fdff017b62979d47572557a0 381 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 3 381 6.8E-116 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Theos_1217 ed18b9a5fdff017b62979d47572557a0 381 Pfam PF01960 ArgJ family 11 381 4.2E-131 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Theos_1217 ed18b9a5fdff017b62979d47572557a0 381 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 381 2.0E-146 T 14-10-2018 Theos_1217 ed18b9a5fdff017b62979d47572557a0 381 Gene3D G3DSA:3.10.20.340 255 381 1.7E-43 T 14-10-2018 Theos_1217 ed18b9a5fdff017b62979d47572557a0 381 SUPERFAMILY SSF56266 6 377 8.11E-129 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Theos_1217 ed18b9a5fdff017b62979d47572557a0 381 Gene3D G3DSA:3.60.70.12 1 254 1.1E-87 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Theos_1217 ed18b9a5fdff017b62979d47572557a0 381 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 381 127.696 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 ProSitePatterns PS00056 Ribosomal protein S17 signature. 54 66 - T 14-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 3 73 4.9E-35 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 PRINTS PR00973 Ribosomal protein S17 family signature 64 71 5.1E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 PRINTS PR00973 Ribosomal protein S17 family signature 22 45 5.1E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 PRINTS PR00973 Ribosomal protein S17 family signature 54 64 5.1E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 Gene3D G3DSA:2.40.50.140 2 105 6.5E-46 T 14-10-2018 Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 SUPERFAMILY SSF50249 3 100 3.77E-33 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 78 24.189 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 Pfam PF00366 Ribosomal protein S17 8 74 5.2E-33 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0286 c3ccf9241c0298a6ac00d5a735d6de92 105 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 3 74 7.0E-32 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0479 0d818e3b98c45b285fd7d87661a7ed5e 475 TIGRFAM TIGR03022 WbaP_sugtrans: undecaprenyl-phosphate galactose phosphotransferase WbaP 22 475 1.3E-163 T 14-10-2018 IPR017472 Undecaprenyl-phosphate galactose phosphotransferase, WbaP GO:0000271|GO:0005886|GO:0016021|GO:0016740 Theos_0479 0d818e3b98c45b285fd7d87661a7ed5e 475 Pfam PF02397 Bacterial sugar transferase 278 469 2.5E-67 T 14-10-2018 IPR003362 Bacterial sugar transferase Theos_0479 0d818e3b98c45b285fd7d87661a7ed5e 475 SUPERFAMILY SSF51735 148 235 8.66E-11 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0479 0d818e3b98c45b285fd7d87661a7ed5e 475 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 26 475 2.6E-125 T 14-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Theos_0479 0d818e3b98c45b285fd7d87661a7ed5e 475 Gene3D G3DSA:3.40.50.720 146 260 1.2E-16 T 14-10-2018 Theos_0479 0d818e3b98c45b285fd7d87661a7ed5e 475 Pfam PF13727 CoA-binding domain 78 242 4.2E-14 T 14-10-2018 Theos_0052 6c02f6248769ac17f96ae68bc85de33e 336 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 335 33.624 T 14-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 Theos_0052 6c02f6248769ac17f96ae68bc85de33e 336 SUPERFAMILY SSF51395 24 328 1.97E-67 T 14-10-2018 Theos_0052 6c02f6248769ac17f96ae68bc85de33e 336 Pfam PF01070 FMN-dependent dehydrogenase 173 325 1.4E-14 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 Theos_0052 6c02f6248769ac17f96ae68bc85de33e 336 Pfam PF01070 FMN-dependent dehydrogenase 6 96 2.5E-10 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 Theos_0052 6c02f6248769ac17f96ae68bc85de33e 336 PIRSF PIRSF003314 1 331 8.2E-102 T 14-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 Theos_0052 6c02f6248769ac17f96ae68bc85de33e 336 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 326 1.6E-96 T 14-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 Theos_0052 6c02f6248769ac17f96ae68bc85de33e 336 Gene3D G3DSA:3.20.20.70 2 332 5.4E-105 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 303 4.7E-122 T 14-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 SUPERFAMILY SSF53784 1 319 1.83E-114 T 14-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 ProSitePatterns PS00433 Phosphofructokinase signature. 246 264 - T 14-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PIRSF PIRSF000532 1 320 4.8E-118 T 14-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 Gene3D G3DSA:3.40.50.450 4 304 6.8E-107 T 14-10-2018 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 Pfam PF00365 Phosphofructokinase 3 278 3.7E-107 T 14-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 4.3E-84 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 4.3E-84 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 4.3E-84 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 4.3E-84 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 4.3E-84 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 242 264 4.3E-84 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 4.3E-84 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 4.3E-84 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 4.3E-84 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 Gene3D G3DSA:3.40.50.460 141 258 6.8E-107 T 14-10-2018 Theos_2195 2eb25a8d6de8acc8412a3264e417e11a 322 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 321 47.363 T 14-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 SUPERFAMILY SSF52935 323 474 1.22E-42 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 14-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 SUPERFAMILY SSF50800 73 168 9.24E-29 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 Gene3D G3DSA:3.20.20.60 5 335 5.5E-184 T 14-10-2018 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 Gene3D G3DSA:3.40.1380.20 336 469 5.5E-184 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 PRINTS PR01050 Pyruvate kinase family signature 269 293 8.8E-68 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 PRINTS PR01050 Pyruvate kinase family signature 313 329 8.8E-68 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 PRINTS PR01050 Pyruvate kinase family signature 62 78 8.8E-68 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 PRINTS PR01050 Pyruvate kinase family signature 187 201 8.8E-68 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 PRINTS PR01050 Pyruvate kinase family signature 217 243 8.8E-68 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 PRINTS PR01050 Pyruvate kinase family signature 244 268 8.8E-68 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 PRINTS PR01050 Pyruvate kinase family signature 294 312 8.8E-68 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 473 4.6E-172 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 Pfam PF00224 Pyruvate kinase, barrel domain 5 338 2.6E-128 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 Gene3D G3DSA:2.40.33.10 73 169 5.5E-184 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 SUPERFAMILY SSF51621 4 341 8.72E-100 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Theos_0004 48135d43493103c7e4ddb267b0e2abfd 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 470 6.8E-35 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Theos_1227 2e067106230f7945f36282d08b8f1ebe 529 Gene3D G3DSA:1.10.238.260 282 379 4.2E-27 T 14-10-2018 Theos_1227 2e067106230f7945f36282d08b8f1ebe 529 SUPERFAMILY SSF51569 2 291 1.32E-78 T 14-10-2018 Theos_1227 2e067106230f7945f36282d08b8f1ebe 529 Pfam PF08502 LeuA allosteric (dimerisation) domain 390 513 1.1E-16 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1227 2e067106230f7945f36282d08b8f1ebe 529 Pfam PF00682 HMGL-like 2 248 7.0E-40 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Theos_1227 2e067106230f7945f36282d08b8f1ebe 529 Gene3D G3DSA:3.20.20.70 1 280 5.1E-78 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1227 2e067106230f7945f36282d08b8f1ebe 529 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 2 516 2.2E-203 T 14-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 Theos_1227 2e067106230f7945f36282d08b8f1ebe 529 SUPERFAMILY SSF110921 396 509 6.54E-13 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1227 2e067106230f7945f36282d08b8f1ebe 529 SMART SM00917 371 514 5.9E-33 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1227 2e067106230f7945f36282d08b8f1ebe 529 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 9 25 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_0327 e175d20aa8d565fa4dc925e3a93f1ef6 225 PIRSF PIRSF001586 1 223 3.7E-87 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0327 e175d20aa8d565fa4dc925e3a93f1ef6 225 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 223 45.646 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0327 e175d20aa8d565fa4dc925e3a93f1ef6 225 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 221 1.8E-96 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0327 e175d20aa8d565fa4dc925e3a93f1ef6 225 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 208 1.0E-48 T 14-10-2018 Theos_0327 e175d20aa8d565fa4dc925e3a93f1ef6 225 SMART SM01211 1 225 5.0E-132 T 14-10-2018 Theos_0327 e175d20aa8d565fa4dc925e3a93f1ef6 225 SUPERFAMILY SSF52317 1 221 5.37E-77 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_0327 e175d20aa8d565fa4dc925e3a93f1ef6 225 Gene3D G3DSA:3.40.50.880 1 223 1.0E-72 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1215 9c8cb557d9ada49b6d03df8c30263ddb 215 Pfam PF03797 Autotransporter beta-domain 63 215 3.9E-5 T 14-10-2018 IPR005546 Autotransporter beta-domain Theos_1215 9c8cb557d9ada49b6d03df8c30263ddb 215 Gene3D G3DSA:2.40.160.70 3 215 2.0E-73 T 14-10-2018 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 SMART SM00840 361 421 2.5E-9 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 SUPERFAMILY SSF52374 5 323 4.02E-88 T 14-10-2018 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 Gene3D G3DSA:3.40.50.620 1 315 4.0E-127 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 Pfam PF09190 DALR domain 362 418 5.4E-8 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 Gene3D G3DSA:1.20.120.640 317 478 6.2E-32 T 14-10-2018 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 479 36.572 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 SUPERFAMILY SSF47323 349 478 6.41E-26 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.8E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 202 220 1.8E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.8E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 233 254 1.8E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 477 1.1E-141 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 Theos_1528 71e1fbfd8afd3ca0296ae3ca9162226f 479 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 322 1.7E-106 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 Theos_2124 f4a65b5464fec2f1ffdcf29b6b3a859f 101 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 6.4E-15 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2124 f4a65b5464fec2f1ffdcf29b6b3a859f 101 Pfam PF01250 Ribosomal protein S6 4 92 6.9E-19 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2124 f4a65b5464fec2f1ffdcf29b6b3a859f 101 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 17.019 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 Theos_2124 f4a65b5464fec2f1ffdcf29b6b3a859f 101 Gene3D G3DSA:3.30.70.60 1 54 7.2E-15 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 Theos_2124 f4a65b5464fec2f1ffdcf29b6b3a859f 101 Gene3D G3DSA:3.30.70.60 55 98 4.6E-13 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 Theos_2124 f4a65b5464fec2f1ffdcf29b6b3a859f 101 SUPERFAMILY SSF54995 1 93 3.27E-21 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2124 f4a65b5464fec2f1ffdcf29b6b3a859f 101 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 14-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 Theos_1735 59229d53a11d6e4cc7d468b21930e428 478 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 193 201 - T 14-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1735 59229d53a11d6e4cc7d468b21930e428 478 SUPERFAMILY SSF51649 147 473 6.81E-137 T 14-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1735 59229d53a11d6e4cc7d468b21930e428 478 Hamap MF_01338 Ribulose bisphosphate carboxylase large chain [rbcL]. 5 471 55.535 T 14-10-2018 IPR020888 Ribulose bisphosphate carboxylase large subunit, type I GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1735 59229d53a11d6e4cc7d468b21930e428 478 Gene3D G3DSA:3.30.70.150 19 145 3.6E-51 T 14-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1735 59229d53a11d6e4cc7d468b21930e428 478 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 21 141 2.1E-45 T 14-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1735 59229d53a11d6e4cc7d468b21930e428 478 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 151 458 6.4E-134 T 14-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1735 59229d53a11d6e4cc7d468b21930e428 478 Gene3D G3DSA:3.20.20.110 147 476 5.6E-134 T 14-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1735 59229d53a11d6e4cc7d468b21930e428 478 SUPERFAMILY SSF54966 10 146 9.03E-58 T 14-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_2161 3d3652a6981b5325f02a22b537532520 427 Gene3D G3DSA:3.40.190.10 145 418 3.8E-95 T 14-10-2018 Theos_2161 3d3652a6981b5325f02a22b537532520 427 SUPERFAMILY SSF53850 33 405 7.06E-72 T 14-10-2018 Theos_2161 3d3652a6981b5325f02a22b537532520 427 Gene3D G3DSA:3.40.190.10 57 377 3.8E-95 T 14-10-2018 Theos_2161 3d3652a6981b5325f02a22b537532520 427 Pfam PF13416 Bacterial extracellular solute-binding protein 50 365 3.4E-29 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 Pfam PF00701 Dihydrodipicolinate synthetase family 2 286 2.1E-84 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 286 9.8E-86 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 288 57.911 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 TIGRFAM TIGR02313 HpaI-NOT-DapA: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 2 293 1.8E-159 T 14-10-2018 IPR012691 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase variant GO:0005737|GO:0008840|GO:0019877 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 SMART SM01130 1 290 7.3E-126 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 Gene3D G3DSA:3.20.20.70 1 293 6.2E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 9.3E-27 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 102 118 9.3E-27 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 9.3E-27 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 9.3E-27 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 PIRSF PIRSF001365 1 296 5.6E-88 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 164 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 Theos_0969 f19be617e2ef0b6c6a7bdc127340b0e3 296 SUPERFAMILY SSF51569 1 292 8.69E-96 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 Gene3D G3DSA:3.30.230.10 455 690 6.2E-87 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 SUPERFAMILY SSF52540 12 422 8.26E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 559 578 4.0E-9 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 45 64 4.0E-9 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 619 637 4.0E-9 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 589 608 4.0E-9 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 Gene3D G3DSA:1.10.8.60 377 453 3.8E-27 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 Pfam PF13654 AAA domain 163 453 1.1E-36 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 Pfam PF13654 AAA domain 19 153 2.0E-12 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 Gene3D G3DSA:3.40.50.300 165 376 1.1E-41 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 Gene3D G3DSA:3.40.50.300 2 140 1.8E-14 T 14-10-2018 Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 SUPERFAMILY SSF54211 477 670 8.72E-33 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_1875 600feeb459ef82c021c96b488fd1d95a 696 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 562 666 3.4E-9 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Theos_0490 8e461643c606704b07d00a3a235e5fab 145 ProSitePatterns PS01029 Dehydroquinase class II signature. 5 22 - T 14-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Theos_0490 8e461643c606704b07d00a3a235e5fab 145 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 15 140 3.0E-52 T 14-10-2018 Theos_0490 8e461643c606704b07d00a3a235e5fab 145 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 145 63.744 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Theos_0490 8e461643c606704b07d00a3a235e5fab 145 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 1 141 7.3E-59 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Theos_0490 8e461643c606704b07d00a3a235e5fab 145 PIRSF PIRSF001399 1 144 2.1E-59 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Theos_0490 8e461643c606704b07d00a3a235e5fab 145 Gene3D G3DSA:3.40.50.9100 1 145 5.5E-64 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Theos_0490 8e461643c606704b07d00a3a235e5fab 145 SUPERFAMILY SSF52304 2 142 2.75E-57 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Theos_0490 8e461643c606704b07d00a3a235e5fab 145 Pfam PF01220 Dehydroquinase class II 2 138 2.0E-54 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Theos_0764 d5332dab96d3ea664023923b47912a62 327 PIRSF PIRSF000102 1 326 7.1E-71 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Theos_0764 d5332dab96d3ea664023923b47912a62 327 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 155 167 - T 14-10-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Theos_0764 d5332dab96d3ea664023923b47912a62 327 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 156 323 3.4E-39 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 Theos_0764 d5332dab96d3ea664023923b47912a62 327 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 3 321 1.2E-152 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 Theos_0764 d5332dab96d3ea664023923b47912a62 327 Gene3D G3DSA:3.40.50.720 1 154 4.5E-58 T 14-10-2018 Theos_0764 d5332dab96d3ea664023923b47912a62 327 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 152 8.2E-38 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_0764 d5332dab96d3ea664023923b47912a62 327 Gene3D G3DSA:3.90.110.10 155 326 5.0E-64 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Theos_0764 d5332dab96d3ea664023923b47912a62 327 SUPERFAMILY SSF56327 156 323 2.16E-59 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Theos_0764 d5332dab96d3ea664023923b47912a62 327 Hamap MF_01517 Malate dehydrogenase [mdh]. 1 325 55.294 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 Theos_0764 d5332dab96d3ea664023923b47912a62 327 SUPERFAMILY SSF51735 1 155 9.27E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 1.8E-165 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 SMART SM00382 57 228 6.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 Hamap MF_00268 Protein RecA [recA]. 5 330 51.353 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 Pfam PF00154 recA bacterial DNA recombination protein 7 268 3.2E-138 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 ProSitePatterns PS00321 recA signature. 213 221 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 SUPERFAMILY SSF54752 273 325 1.83E-16 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 PRINTS PR00142 RecA protein signature 93 122 4.0E-76 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 PRINTS PR00142 RecA protein signature 165 194 4.0E-76 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 PRINTS PR00142 RecA protein signature 127 156 4.0E-76 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 PRINTS PR00142 RecA protein signature 210 238 4.0E-76 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 PRINTS PR00142 RecA protein signature 298 315 4.0E-76 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 PRINTS PR00142 RecA protein signature 244 273 4.0E-76 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 Gene3D G3DSA:3.30.250.10 269 327 5.9E-22 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 SUPERFAMILY SSF52540 4 268 1.17E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0180 9765a2596a88da73bc8fa993eb4428e9 340 Gene3D G3DSA:3.40.50.300 26 268 6.7E-83 T 14-10-2018 Theos_1773 f95c696874ee720a2c747b055a98cc9a 253 SUPERFAMILY SSF52540 4 249 7.61E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1773 f95c696874ee720a2c747b055a98cc9a 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 1.8E-10 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Theos_1773 f95c696874ee720a2c747b055a98cc9a 253 Pfam PF00005 ABC transporter 19 180 1.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1773 f95c696874ee720a2c747b055a98cc9a 253 Gene3D G3DSA:3.40.50.300 2 252 1.9E-66 T 14-10-2018 Theos_1773 f95c696874ee720a2c747b055a98cc9a 253 SMART SM00382 28 227 4.3E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1280 aed2bd177c20adbe9cbbcfc37db87d1b 500 Pfam PF02446 4-alpha-glucanotransferase 11 477 2.7E-159 T 14-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Theos_1280 aed2bd177c20adbe9cbbcfc37db87d1b 500 SUPERFAMILY SSF51445 5 493 2.34E-171 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily Theos_1280 aed2bd177c20adbe9cbbcfc37db87d1b 500 Gene3D G3DSA:3.20.20.80 1 500 1.4E-215 T 14-10-2018 Theos_1280 aed2bd177c20adbe9cbbcfc37db87d1b 500 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 4 486 1.6E-104 T 14-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Theos_1755 e083b9e1b789303a91c43312d59bc3b5 518 PRINTS PR00723 Subtilisin serine protease family (S8) signature 163 182 1.2E-15 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_1755 e083b9e1b789303a91c43312d59bc3b5 518 PRINTS PR00723 Subtilisin serine protease family (S8) signature 461 477 1.2E-15 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_1755 e083b9e1b789303a91c43312d59bc3b5 518 PRINTS PR00723 Subtilisin serine protease family (S8) signature 233 246 1.2E-15 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_1755 e083b9e1b789303a91c43312d59bc3b5 518 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 237 247 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site Theos_1755 e083b9e1b789303a91c43312d59bc3b5 518 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 462 472 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site Theos_1755 e083b9e1b789303a91c43312d59bc3b5 518 Pfam PF00082 Subtilase family 166 509 6.6E-45 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Theos_1755 e083b9e1b789303a91c43312d59bc3b5 518 SUPERFAMILY SSF52743 142 517 1.02E-63 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_1755 e083b9e1b789303a91c43312d59bc3b5 518 Gene3D G3DSA:3.40.50.200 108 518 6.3E-75 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_1755 e083b9e1b789303a91c43312d59bc3b5 518 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 168 179 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site Theos_2320 4af2c8666d995d81a5ffdbef26309cb0 246 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 207 1.4E-38 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Theos_2320 4af2c8666d995d81a5ffdbef26309cb0 246 Gene3D G3DSA:3.30.950.10 112 228 2.9E-28 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Theos_2320 4af2c8666d995d81a5ffdbef26309cb0 246 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Theos_2320 4af2c8666d995d81a5ffdbef26309cb0 246 Gene3D G3DSA:3.40.1010.10 2 111 3.2E-25 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Theos_2320 4af2c8666d995d81a5ffdbef26309cb0 246 SUPERFAMILY SSF53790 1 244 1.44E-56 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Theos_0199 1ccd94def4094e6e9ef67ea03faa8b4c 235 SUPERFAMILY SSF51261 100 208 1.67E-16 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_0199 1ccd94def4094e6e9ef67ea03faa8b4c 235 Gene3D G3DSA:2.70.70.10 75 217 2.5E-17 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_0199 1ccd94def4094e6e9ef67ea03faa8b4c 235 Pfam PF01551 Peptidase family M23 99 208 5.8E-12 T 14-10-2018 IPR016047 Peptidase M23 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 SUPERFAMILY SSF55347 114 250 1.6E-49 T 14-10-2018 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 366 41.138 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 364 8.1E-109 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 Pfam PF13288 DXP reductoisomerase C-terminal domain 248 361 1.1E-35 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 SUPERFAMILY SSF69055 278 366 1.44E-25 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 SUPERFAMILY SSF51735 2 138 9.79E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 120 2.1E-27 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 Gene3D G3DSA:1.10.1740.10 287 367 1.5E-24 T 14-10-2018 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 PIRSF PIRSF006205 1 367 2.6E-126 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 134 216 1.2E-33 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Theos_1333 2602cf500ff6fa3d75d6ba0b57ac57bf 367 Gene3D G3DSA:3.40.50.720 1 138 6.7E-37 T 14-10-2018 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 Gene3D G3DSA:2.40.30.20 1 71 8.0E-31 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 199 1.8E-42 T 14-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 Gene3D G3DSA:3.40.50.300 73 429 1.9E-179 T 14-10-2018 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 208 429 3.6E-90 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 SUPERFAMILY SSF50615 3 70 6.28E-12 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 3.5E-14 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 SUPERFAMILY SSF47917 442 544 6.02E-26 T 14-10-2018 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 Gene3D G3DSA:1.10.1140.10 430 578 1.2E-50 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 577 51.026 T 14-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 SUPERFAMILY SSF52540 145 433 7.51E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 420 429 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_0821 1c199afcfb483ee4fe83316eb0e8c539 578 Gene3D G3DSA:2.40.50.100 115 181 1.9E-179 T 14-10-2018 Theos_1767 4f20b3ad32249d79339166544b6dff04 246 SMART SM00382 28 211 4.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1767 4f20b3ad32249d79339166544b6dff04 246 Pfam PF00005 ABC transporter 19 162 2.4E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1767 4f20b3ad32249d79339166544b6dff04 246 Gene3D G3DSA:3.40.50.300 3 236 7.9E-61 T 14-10-2018 Theos_1767 4f20b3ad32249d79339166544b6dff04 246 SUPERFAMILY SSF52540 3 222 1.3E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 Pfam PF02151 UvrB/uvrC motif 196 228 3.8E-10 T 14-10-2018 IPR001943 UVR domain GO:0005515 Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 SMART SM00465 12 89 1.5E-16 T 14-10-2018 IPR000305 GIY-YIG endonuclease Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 Gene3D G3DSA:3.40.1440.10 3 92 2.1E-28 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 Gene3D G3DSA:3.30.420.340 368 528 1.5E-47 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 SUPERFAMILY SSF47781 498 586 6.04E-16 T 14-10-2018 IPR010994 RuvA domain 2-like Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 374 516 2.0E-42 T 14-10-2018 IPR001162 UvrC family homology region Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 Gene3D G3DSA:1.10.150.20 533 586 5.8E-15 T 14-10-2018 Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 SUPERFAMILY SSF46600 180 230 6.93E-12 T 14-10-2018 IPR036876 UVR domain superfamily Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 SMART SM00278 532 551 49.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 SMART SM00278 564 583 5.1 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 SUPERFAMILY SSF82771 12 91 1.26E-17 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 Pfam PF01541 GIY-YIG catalytic domain 14 81 7.2E-7 T 14-10-2018 IPR000305 GIY-YIG endonuclease Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 Pfam PF14520 Helix-hairpin-helix domain 531 586 8.0E-9 T 14-10-2018 Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 Gene3D G3DSA:4.10.860.10 188 232 9.9E-7 T 14-10-2018 Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 565 3.7E-156 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Theos_1711 2f972c6cd6b8e90b9f7be146b8aa71ca 592 Hamap MF_00203 UvrABC system protein C [uvrC]. 1 583 26.469 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Theos_2226 16e5fa790c990da3a5e71a80307860be 217 Gene3D G3DSA:3.50.30.100 2 187 4.9E-46 T 14-10-2018 Theos_2226 16e5fa790c990da3a5e71a80307860be 217 SUPERFAMILY SSF89562 13 175 9.16E-42 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily Theos_2226 16e5fa790c990da3a5e71a80307860be 217 Pfam PF03737 Aldolase/RraA 27 163 1.4E-34 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein Theos_2421 16657c98dc93bd217ab37fb1f01506d0 287 SUPERFAMILY SSF46785 31 82 9.38E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2421 16657c98dc93bd217ab37fb1f01506d0 287 Pfam PF12840 Helix-turn-helix domain 33 74 2.2E-6 T 14-10-2018 Theos_2421 16657c98dc93bd217ab37fb1f01506d0 287 Gene3D G3DSA:3.30.450.40 108 280 2.0E-26 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_2421 16657c98dc93bd217ab37fb1f01506d0 287 Pfam PF01614 Bacterial transcriptional regulator 158 247 9.9E-19 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal Theos_2421 16657c98dc93bd217ab37fb1f01506d0 287 SUPERFAMILY SSF55781 157 244 2.06E-22 T 14-10-2018 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 393 55.934 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 Gene3D G3DSA:3.30.300.10 7 246 1.7E-172 T 14-10-2018 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 271 279 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 102 1.1E-39 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 127 137 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 SUPERFAMILY SSF55973 245 393 1.37E-65 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 SUPERFAMILY SSF55973 122 244 1.1E-48 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 245 381 1.4E-63 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 SUPERFAMILY SSF55973 6 110 2.55E-43 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 Gene3D G3DSA:3.30.300.10 12 283 1.7E-172 T 14-10-2018 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 PIRSF PIRSF000497 1 394 1.2E-163 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 Gene3D G3DSA:3.30.300.10 111 387 1.7E-172 T 14-10-2018 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 391 9.0E-172 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_0387 d1618bc3e041e56b9d5a91799213592d 395 Pfam PF02772 S-adenosylmethionine synthetase, central domain 126 243 4.1E-45 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Theos_1404 cb7d434df82f05ee7d2f8dc55c9220d5 83 PRINTS PR01249 Ribosomal protein L31 signature 42 57 5.4E-21 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1404 cb7d434df82f05ee7d2f8dc55c9220d5 83 PRINTS PR01249 Ribosomal protein L31 signature 14 31 5.4E-21 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1404 cb7d434df82f05ee7d2f8dc55c9220d5 83 PRINTS PR01249 Ribosomal protein L31 signature 57 75 5.4E-21 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1404 cb7d434df82f05ee7d2f8dc55c9220d5 83 SUPERFAMILY SSF143800 14 76 9.81E-25 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1404 cb7d434df82f05ee7d2f8dc55c9220d5 83 TIGRFAM TIGR00105 L31: ribosomal protein bL31 14 76 1.0E-26 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1404 cb7d434df82f05ee7d2f8dc55c9220d5 83 Gene3D G3DSA:2.30.170.50 13 80 1.5E-29 T 14-10-2018 Theos_1404 cb7d434df82f05ee7d2f8dc55c9220d5 83 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 13 79 28.623 T 14-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1404 cb7d434df82f05ee7d2f8dc55c9220d5 83 ProSitePatterns PS01143 Ribosomal protein L31 signature. 46 67 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1404 cb7d434df82f05ee7d2f8dc55c9220d5 83 Pfam PF01197 Ribosomal protein L31 14 76 1.8E-29 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1959 f7f36e1d4442959de67d598eb612ddea 183 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 157 1.1E-13 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Theos_1959 f7f36e1d4442959de67d598eb612ddea 183 Gene3D G3DSA:1.10.1670.40 6 180 1.8E-54 T 14-10-2018 Theos_1959 f7f36e1d4442959de67d598eb612ddea 183 SMART SM00478 38 183 4.4E-21 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Theos_1959 f7f36e1d4442959de67d598eb612ddea 183 SUPERFAMILY SSF48150 25 181 1.45E-41 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Theos_1959 f7f36e1d4442959de67d598eb612ddea 183 Gene3D G3DSA:1.10.340.30 26 134 1.8E-54 T 14-10-2018 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 Gene3D G3DSA:1.20.140.10 230 379 1.0E-53 T 14-10-2018 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 PIRSF PIRSF016578 2 78 0.0072 T 14-10-2018 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 PIRSF PIRSF016578 95 376 7.9E-14 T 14-10-2018 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 331 350 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 114 6.3E-29 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 371 2.6E-47 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 120 132 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 SUPERFAMILY SSF47203 222 375 4.67E-56 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 212 7.9E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 Gene3D G3DSA:1.10.540.10 3 115 3.5E-32 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 SUPERFAMILY SSF56645 4 237 3.53E-76 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_1361 9d3144406112a6825c9ffa0482fb5348 379 Gene3D G3DSA:2.40.110.10 117 229 6.5E-41 T 14-10-2018 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 Pfam PF00549 CoA-ligase 255 367 1.4E-14 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 Gene3D G3DSA:3.30.470.20 3 220 2.5E-97 T 14-10-2018 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 SUPERFAMILY SSF56059 1 227 3.71E-77 T 14-10-2018 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 373 2.5E-142 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 PIRSF PIRSF001554 1 377 1.3E-141 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 375 39.986 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 Gene3D G3DSA:3.40.50.261 231 378 3.3E-50 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 Gene3D G3DSA:3.30.1490.20 21 96 2.5E-97 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 248 273 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 Pfam PF08442 ATP-grasp domain 2 194 6.1E-76 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0766 d047d2743d01cf6ba7d8f41be2b29eb7 378 SUPERFAMILY SSF52210 231 374 1.96E-45 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0852 8e507cde6bdb7fc15af869caf4ca6b17 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 334 1.8E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 Gene3D G3DSA:3.40.50.300 218 365 1.1E-82 T 14-10-2018 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 Pfam PF01926 50S ribosome-binding GTPase 220 306 7.8E-19 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 218 305 4.6E-16 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 Gene3D G3DSA:3.30.1360.120 1 124 2.1E-44 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 Pfam PF12631 MnmE helical domain 127 429 1.9E-41 T 14-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 432 30.915 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 124 3.0E-38 T 14-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 432 1.6E-100 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 287 305 1.4E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 220 240 1.4E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 SUPERFAMILY SSF52540 77 356 2.76E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0943 1fbad697b82b18d1febc23ecc35ead20 432 Gene3D G3DSA:1.20.120.430 125 432 1.1E-82 T 14-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 Theos_0368 d9922fb2c5a272b686a4e9905ee6ad01 130 SUPERFAMILY SSF102712 5 119 9.55E-21 T 14-10-2018 Theos_0368 d9922fb2c5a272b686a4e9905ee6ad01 130 Pfam PF14464 Prokaryotic homologs of the JAB domain 9 108 4.9E-19 T 14-10-2018 IPR028090 JAB domain, prokaryotic Theos_0368 d9922fb2c5a272b686a4e9905ee6ad01 130 Gene3D G3DSA:3.40.140.10 4 126 1.2E-25 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 195 503 1.3E-127 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 503 50.141 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 Pfam PF00117 Glutamine amidotransferase class-I 3 181 1.6E-42 T 14-10-2018 IPR017926 Glutamine amidotransferase Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 Pfam PF00958 GMP synthase C terminal domain 413 502 3.7E-38 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 SUPERFAMILY SSF52317 1 183 6.51E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 Pfam PF01171 PP-loop family 212 252 2.6E-4 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 3.8E-8 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 3.8E-8 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 160 173 3.8E-8 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 SUPERFAMILY SSF52402 180 424 1.3E-45 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 184 2.0E-69 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 PRINTS PR00097 Anthranilate synthase component II signature 46 55 5.0E-6 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 PRINTS PR00097 Anthranilate synthase component II signature 73 84 5.0E-6 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 PRINTS PR00097 Anthranilate synthase component II signature 160 173 5.0E-6 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 SUPERFAMILY SSF54810 383 503 5.23E-48 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 Gene3D G3DSA:3.40.50.620 191 383 5.8E-63 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 Gene3D G3DSA:3.30.300.10 384 503 2.2E-50 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 7.3E-6 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 2 16 7.3E-6 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 7.3E-6 T 14-10-2018 Theos_0652 8bbdaa420358028ecb61def7b4f49356 503 Gene3D G3DSA:3.40.50.880 1 188 3.4E-60 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_0451 ae1f31c2e296863d23a14ad1f3c9d8b0 251 Gene3D G3DSA:3.40.1090.20 1 83 9.3E-17 T 14-10-2018 Theos_0451 ae1f31c2e296863d23a14ad1f3c9d8b0 251 Gene3D G3DSA:3.40.1090.10 84 206 2.6E-19 T 14-10-2018 Theos_0451 ae1f31c2e296863d23a14ad1f3c9d8b0 251 SUPERFAMILY SSF52151 2 243 4.19E-53 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Theos_0451 ae1f31c2e296863d23a14ad1f3c9d8b0 251 Pfam PF01734 Patatin-like phospholipase 4 159 1.0E-23 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Theos_1756 f8292ac5bc4bdc4cf2a61a57f1d75f60 406 Gene3D G3DSA:3.40.720.10 19 392 2.8E-97 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Theos_1756 f8292ac5bc4bdc4cf2a61a57f1d75f60 406 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 19 395 2.3E-84 T 14-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_1756 f8292ac5bc4bdc4cf2a61a57f1d75f60 406 Gene3D G3DSA:3.30.70.2130 92 233 2.8E-97 T 14-10-2018 Theos_1756 f8292ac5bc4bdc4cf2a61a57f1d75f60 406 SUPERFAMILY SSF53649 16 373 9.82E-32 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Theos_1756 f8292ac5bc4bdc4cf2a61a57f1d75f60 406 Pfam PF01676 Metalloenzyme superfamily 17 394 5.5E-30 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 Theos_1756 f8292ac5bc4bdc4cf2a61a57f1d75f60 406 PIRSF PIRSF006392 13 402 1.9E-121 T 14-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_1756 f8292ac5bc4bdc4cf2a61a57f1d75f60 406 Hamap MF_01402_B 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 16 397 58.871 T 14-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_1756 f8292ac5bc4bdc4cf2a61a57f1d75f60 406 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 51 220 4.5E-46 T 14-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_1268 845a3663d0af6d4cc40b8d0bcca23ae1 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 534 612 9.3E-32 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Theos_1268 845a3663d0af6d4cc40b8d0bcca23ae1 648 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 27 646 0.0 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 Theos_1268 845a3663d0af6d4cc40b8d0bcca23ae1 648 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 9 648 53.973 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 Theos_1268 845a3663d0af6d4cc40b8d0bcca23ae1 648 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 85 1.3E-23 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Theos_1268 845a3663d0af6d4cc40b8d0bcca23ae1 648 Gene3D G3DSA:3.30.300.30 521 648 2.8E-34 T 14-10-2018 Theos_1268 845a3663d0af6d4cc40b8d0bcca23ae1 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 263 274 - T 14-10-2018 IPR020845 AMP-binding, conserved site Theos_1268 845a3663d0af6d4cc40b8d0bcca23ae1 648 SUPERFAMILY SSF56801 17 644 5.49E-189 T 14-10-2018 Theos_1268 845a3663d0af6d4cc40b8d0bcca23ae1 648 Gene3D G3DSA:3.40.50.12780 61 518 3.1E-107 T 14-10-2018 Theos_1268 845a3663d0af6d4cc40b8d0bcca23ae1 648 Pfam PF00501 AMP-binding enzyme 87 525 4.4E-94 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_0922 40645eb9570bedad80b640fc33806374 133 SUPERFAMILY SSF54637 1 129 1.63E-37 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_0922 40645eb9570bedad80b640fc33806374 133 Gene3D G3DSA:3.10.129.10 1 128 1.8E-38 T 14-10-2018 Theos_0922 40645eb9570bedad80b640fc33806374 133 Pfam PF03061 Thioesterase superfamily 17 99 7.6E-16 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Theos_0922 40645eb9570bedad80b640fc33806374 133 PIRSF PIRSF003230 1 132 4.9E-32 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 Theos_0922 40645eb9570bedad80b640fc33806374 133 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 6 110 2.9E-21 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 Theos_2373 3c83c18ab1e188e79c2dabd4de731360 207 Gene3D G3DSA:1.10.10.1320 2 71 1.2E-11 T 14-10-2018 Theos_2373 3c83c18ab1e188e79c2dabd4de731360 207 Pfam PF10099 Anti-sigma-K factor rskA 59 199 3.6E-12 T 14-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 Theos_2373 3c83c18ab1e188e79c2dabd4de731360 207 Pfam PF13490 Putative zinc-finger 4 31 6.1E-5 T 14-10-2018 IPR027383 Putative zinc-finger Theos_1545 3577e9cf8bd17d86c6c63f893a862bd8 356 Pfam PF13439 Glycosyltransferase Family 4 89 162 2.1E-8 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Theos_1545 3577e9cf8bd17d86c6c63f893a862bd8 356 Pfam PF00534 Glycosyl transferases group 1 184 330 5.3E-23 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Theos_1545 3577e9cf8bd17d86c6c63f893a862bd8 356 Gene3D G3DSA:3.40.50.2000 158 335 6.3E-51 T 14-10-2018 Theos_1545 3577e9cf8bd17d86c6c63f893a862bd8 356 Gene3D G3DSA:3.40.50.2000 69 346 6.3E-51 T 14-10-2018 Theos_1545 3577e9cf8bd17d86c6c63f893a862bd8 356 SUPERFAMILY SSF53756 2 348 1.66E-62 T 14-10-2018 Theos_0868 eba1b7e6e804a93d96f7331aaff87019 229 SUPERFAMILY SSF52833 4 125 7.93E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0868 eba1b7e6e804a93d96f7331aaff87019 229 SUPERFAMILY SSF52833 131 223 6.67E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0868 eba1b7e6e804a93d96f7331aaff87019 229 Gene3D G3DSA:3.40.30.10 130 222 5.5E-26 T 14-10-2018 Theos_0868 eba1b7e6e804a93d96f7331aaff87019 229 Pfam PF13192 Thioredoxin domain 146 221 9.0E-15 T 14-10-2018 IPR012336 Thioredoxin-like fold Theos_0868 eba1b7e6e804a93d96f7331aaff87019 229 Gene3D G3DSA:3.40.30.10 3 120 4.5E-28 T 14-10-2018 Theos_0868 eba1b7e6e804a93d96f7331aaff87019 229 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 5 223 6.3E-88 T 14-10-2018 IPR011903 Glutaredoxin-like domain Theos_2229 8fd044338be829698c131873ab57a0f3 215 Gene3D G3DSA:1.10.10.10 2 72 1.5E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2229 8fd044338be829698c131873ab57a0f3 215 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 4.3E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Theos_2229 8fd044338be829698c131873ab57a0f3 215 SMART SM00345 13 71 6.9E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Theos_2229 8fd044338be829698c131873ab57a0f3 215 Pfam PF07729 FCD domain 81 204 1.3E-30 T 14-10-2018 IPR011711 GntR, C-terminal Theos_2229 8fd044338be829698c131873ab57a0f3 215 SMART SM00895 81 205 6.6E-25 T 14-10-2018 IPR011711 GntR, C-terminal Theos_2229 8fd044338be829698c131873ab57a0f3 215 SUPERFAMILY SSF46785 5 75 2.12E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2229 8fd044338be829698c131873ab57a0f3 215 SUPERFAMILY SSF48008 77 212 7.06E-34 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Theos_2229 8fd044338be829698c131873ab57a0f3 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 2.5E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Theos_2229 8fd044338be829698c131873ab57a0f3 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 2.5E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Theos_2229 8fd044338be829698c131873ab57a0f3 215 Gene3D G3DSA:1.20.120.530 74 213 5.3E-35 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Theos_1896 eb768d0209244ab3a10bf3a6bb9faec7 106 Pfam PF04930 FUN14 family 13 103 2.4E-25 T 14-10-2018 IPR007014 FUN14 Theos_0493 2547a0e755988480dd888f0273a5f89c 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 1.1E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0493 2547a0e755988480dd888f0273a5f89c 215 Gene3D G3DSA:3.40.50.12740 2 211 7.0E-75 T 14-10-2018 Theos_0493 2547a0e755988480dd888f0273a5f89c 215 SUPERFAMILY SSF46894 145 211 4.76E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Theos_0493 2547a0e755988480dd888f0273a5f89c 215 SMART SM00448 2 115 3.5E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0493 2547a0e755988480dd888f0273a5f89c 215 Pfam PF00072 Response regulator receiver domain 4 115 7.0E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0493 2547a0e755988480dd888f0273a5f89c 215 SMART SM00421 148 205 6.9E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0493 2547a0e755988480dd888f0273a5f89c 215 SUPERFAMILY SSF52172 2 132 3.56E-36 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0493 2547a0e755988480dd888f0273a5f89c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0493 2547a0e755988480dd888f0273a5f89c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0493 2547a0e755988480dd888f0273a5f89c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_2345 37c03dda21662d807e7386104790f953 432 Pfam PF13416 Bacterial extracellular solute-binding protein 39 357 2.5E-44 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_2345 37c03dda21662d807e7386104790f953 432 SUPERFAMILY SSF53850 22 420 2.85E-75 T 14-10-2018 Theos_2345 37c03dda21662d807e7386104790f953 432 Gene3D G3DSA:3.40.190.10 138 417 1.1E-109 T 14-10-2018 Theos_2345 37c03dda21662d807e7386104790f953 432 Gene3D G3DSA:3.40.190.10 25 378 1.1E-109 T 14-10-2018 Theos_2534 cb701a9d0176ea7c4ea609082521bcaa 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 9.9E-15 T 14-10-2018 IPR032806 H repeat-associated protein, N-terminal Theos_2286 14d0be61bb1cac57fc61fef1a6163dca 284 SUPERFAMILY SSF161098 2 284 2.9E-72 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2286 14d0be61bb1cac57fc61fef1a6163dca 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 272 1.5E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2286 14d0be61bb1cac57fc61fef1a6163dca 284 Gene3D G3DSA:1.10.3720.10 2 271 1.0E-61 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 Gene3D G3DSA:3.40.50.300 142 325 4.1E-71 T 14-10-2018 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 7 608 37.094 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 Pfam PF01434 Peptidase family M41 385 590 1.7E-75 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 Gene3D G3DSA:1.10.8.60 326 403 5.4E-32 T 14-10-2018 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 SUPERFAMILY SSF140990 406 598 1.7E-69 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 Pfam PF06480 FtsH Extracellular 9 94 4.8E-9 T 14-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 Gene3D G3DSA:1.20.58.760 405 600 2.3E-87 T 14-10-2018 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 SMART SM00382 188 327 2.1E-24 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 107 591 2.8E-221 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 Gene3D G3DSA:2.40.50.920 30 105 9.9E-8 T 14-10-2018 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 323 8.6E-44 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_0681 a4a9b8464b57563856447c602b63fdb8 626 SUPERFAMILY SSF52540 148 396 6.14E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1985 1556bc6842ec60e89506557f65ee0c95 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 286 9.6E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_1049 4f0b2ff8aff9e1a3c740520d46ff0468 183 Pfam PF01814 Hemerythrin HHE cation binding domain 89 181 4.3E-6 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Theos_1779 5b11f084a8b459dbdad7f98ac3831abe 303 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 19 264 6.1E-59 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 Theos_1779 5b11f084a8b459dbdad7f98ac3831abe 303 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 268 38.374 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Theos_1779 5b11f084a8b459dbdad7f98ac3831abe 303 Gene3D G3DSA:1.10.8.10 2 79 1.0E-13 T 14-10-2018 Theos_1779 5b11f084a8b459dbdad7f98ac3831abe 303 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 264 3.3E-68 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Theos_1779 5b11f084a8b459dbdad7f98ac3831abe 303 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 173 179 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Theos_1779 5b11f084a8b459dbdad7f98ac3831abe 303 SUPERFAMILY SSF53335 4 266 4.22E-51 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1779 5b11f084a8b459dbdad7f98ac3831abe 303 Gene3D G3DSA:3.40.50.150 80 276 3.5E-52 T 14-10-2018 Theos_1779 5b11f084a8b459dbdad7f98ac3831abe 303 Pfam PF05175 Methyltransferase small domain 101 182 5.7E-14 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Theos_1119 e2d162bbffafb205b13564e7dcf4a1bc 283 PIRSF PIRSF004486 1 282 1.5E-103 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Theos_1119 e2d162bbffafb205b13564e7dcf4a1bc 283 SUPERFAMILY SSF53335 6 280 4.41E-56 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1119 e2d162bbffafb205b13564e7dcf4a1bc 283 SUPERFAMILY SSF81799 107 204 6.02E-36 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 Theos_1119 e2d162bbffafb205b13564e7dcf4a1bc 283 Gene3D G3DSA:1.10.150.170 105 205 3.6E-117 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 Theos_1119 e2d162bbffafb205b13564e7dcf4a1bc 283 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 6 281 38.493 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Theos_1119 e2d162bbffafb205b13564e7dcf4a1bc 283 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 1 280 2.5E-96 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Theos_1119 e2d162bbffafb205b13564e7dcf4a1bc 283 Pfam PF01795 MraW methylase family 4 280 1.8E-98 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Theos_1119 e2d162bbffafb205b13564e7dcf4a1bc 283 Gene3D G3DSA:3.40.50.150 6 279 3.6E-117 T 14-10-2018 Theos_2172 a0e969f55807f106ac22bcf1e74d7a7e 284 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2172 a0e969f55807f106ac22bcf1e74d7a7e 284 Pfam PF00005 ABC transporter 17 158 3.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2172 a0e969f55807f106ac22bcf1e74d7a7e 284 Gene3D G3DSA:3.40.50.300 1 229 1.7E-72 T 14-10-2018 Theos_2172 a0e969f55807f106ac22bcf1e74d7a7e 284 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 5 199 2.0E-40 T 14-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 Theos_2172 a0e969f55807f106ac22bcf1e74d7a7e 284 SMART SM00382 26 206 4.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2172 a0e969f55807f106ac22bcf1e74d7a7e 284 SUPERFAMILY SSF52540 2 217 1.04E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1312 c63fc5264f468f6ebcc705447a56c598 380 Gene3D G3DSA:1.10.150.130 65 173 3.2E-22 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Theos_1312 c63fc5264f468f6ebcc705447a56c598 380 SUPERFAMILY SSF56349 68 365 2.68E-67 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Theos_1312 c63fc5264f468f6ebcc705447a56c598 380 Gene3D G3DSA:1.10.443.10 174 369 3.2E-49 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Theos_1312 c63fc5264f468f6ebcc705447a56c598 380 Pfam PF00589 Phage integrase family 177 357 1.5E-23 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 SUPERFAMILY SSF47807 171 284 1.64E-32 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 ProSitePatterns PS00447 DNA polymerase family A signature. 657 676 - T 14-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 258 4.5E-28 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 TIGRFAM TIGR00593 pola: DNA polymerase I 356 829 1.2E-201 T 14-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Gene3D G3DSA:1.10.150.20 612 755 7.8E-118 T 14-10-2018 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Pfam PF00476 DNA polymerase family A 453 826 2.0E-148 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Gene3D G3DSA:3.30.70.370 565 825 7.8E-118 T 14-10-2018 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 SMART SM00279 173 208 1.8E-15 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Gene3D G3DSA:3.40.50.1010 11 276 4.7E-99 T 14-10-2018 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 SMART SM00482 589 793 3.7E-122 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Gene3D G3DSA:3.30.420.10 291 444 3.7E-66 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 11 170 1.3E-47 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Gene3D G3DSA:1.10.150.20 174 247 4.7E-99 T 14-10-2018 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Gene3D G3DSA:1.20.1060.10 445 561 1.8E-45 T 14-10-2018 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 SUPERFAMILY SSF88723 4 170 9.81E-51 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 SMART SM00475 9 262 1.9E-139 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 Pfam PF09281 Taq polymerase, exonuclease 293 417 3.6E-43 T 14-10-2018 IPR015361 Taq polymerase, thermostable, exonuclease region GO:0001882|GO:0003887|GO:0006260|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 SUPERFAMILY SSF56672 422 829 3.67E-156 T 14-10-2018 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 716 727 3.9E-85 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 748 764 3.9E-85 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 633 646 3.9E-85 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 694 705 3.9E-85 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 603 626 3.9E-85 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 558 580 3.9E-85 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 581 596 3.9E-85 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 657 682 3.9E-85 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 776 789 3.9E-85 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0888 edf7ffbcb00a68047d49d3f20ad32047 830 SUPERFAMILY SSF53098 292 418 1.27E-29 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_0814 998e3b218c886fd52af794d372666bff 380 Gene3D G3DSA:3.30.750.80 67 170 3.3E-30 T 14-10-2018 Theos_0814 998e3b218c886fd52af794d372666bff 380 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 164 342 1.6E-23 T 14-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 Theos_0814 998e3b218c886fd52af794d372666bff 380 SUPERFAMILY SSF88697 1 63 9.19E-30 T 14-10-2018 IPR015947 PUA-like superfamily Theos_0814 998e3b218c886fd52af794d372666bff 380 Gene3D G3DSA:2.30.130.10 1 66 9.0E-25 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 Theos_0814 998e3b218c886fd52af794d372666bff 380 SUPERFAMILY SSF53335 73 375 2.11E-69 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0814 998e3b218c886fd52af794d372666bff 380 Gene3D G3DSA:3.40.50.150 171 380 1.0E-70 T 14-10-2018 Theos_2470 3ee174b379bc8745798e30c821b1b78e 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 269 276 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Theos_2470 3ee174b379bc8745798e30c821b1b78e 502 Gene3D G3DSA:3.40.309.10 274 467 1.4E-173 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Theos_2470 3ee174b379bc8745798e30c821b1b78e 502 SUPERFAMILY SSF53720 19 500 3.53E-165 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_2470 3ee174b379bc8745798e30c821b1b78e 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 297 308 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Theos_2470 3ee174b379bc8745798e30c821b1b78e 502 Pfam PF00171 Aldehyde dehydrogenase family 38 497 2.3E-165 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Theos_2470 3ee174b379bc8745798e30c821b1b78e 502 Gene3D G3DSA:3.40.605.10 31 495 1.4E-173 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_1122 2a47bd6d43496641026dbb26b5fd00d4 418 Pfam PF02875 Mur ligase family, glutamate ligase domain 290 360 1.0E-12 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Theos_1122 2a47bd6d43496641026dbb26b5fd00d4 418 Pfam PF01225 Mur ligase family, catalytic domain 28 71 1.8E-8 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Theos_1122 2a47bd6d43496641026dbb26b5fd00d4 418 SUPERFAMILY SSF53244 290 415 8.7E-30 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_1122 2a47bd6d43496641026dbb26b5fd00d4 418 SUPERFAMILY SSF63418 8 93 1.83E-17 T 14-10-2018 IPR035911 MurE/MurF, N-terminal Theos_1122 2a47bd6d43496641026dbb26b5fd00d4 418 Gene3D G3DSA:3.40.1390.10 3 82 2.6E-14 T 14-10-2018 Theos_1122 2a47bd6d43496641026dbb26b5fd00d4 418 Gene3D G3DSA:3.40.1190.10 83 287 8.1E-32 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_1122 2a47bd6d43496641026dbb26b5fd00d4 418 SUPERFAMILY SSF53623 98 285 6.26E-25 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_1122 2a47bd6d43496641026dbb26b5fd00d4 418 Gene3D G3DSA:3.90.190.20 289 418 5.0E-34 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_1122 2a47bd6d43496641026dbb26b5fd00d4 418 Pfam PF08245 Mur ligase middle domain 102 269 7.2E-14 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Theos_1041 484d645f3c0753c47f6682fc096dbe77 1196 SUPERFAMILY SSF53706 10 1029 0.0 T 14-10-2018 Theos_1041 484d645f3c0753c47f6682fc096dbe77 1196 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1087 1114 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 Theos_1041 484d645f3c0753c47f6682fc096dbe77 1196 Pfam PF00384 Molybdopterin oxidoreductase 92 798 2.6E-124 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1041 484d645f3c0753c47f6682fc096dbe77 1196 SUPERFAMILY SSF50692 1049 1191 4.07E-44 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Theos_1041 484d645f3c0753c47f6682fc096dbe77 1196 Pfam PF01568 Molydopterin dinucleotide binding domain 1051 1164 8.1E-22 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Theos_1041 484d645f3c0753c47f6682fc096dbe77 1196 Gene3D G3DSA:3.40.50.12440 28 1196 0.0 T 14-10-2018 Theos_1041 484d645f3c0753c47f6682fc096dbe77 1196 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 12 1192 0.0 T 14-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Theos_1041 484d645f3c0753c47f6682fc096dbe77 1196 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 32 50 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 Theos_1041 484d645f3c0753c47f6682fc096dbe77 1196 SMART SM00926 27 89 4.3E-4 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1175 c38c559712c4348d724e5c4dbb35ed54 384 Pfam PF02803 Thiolase, C-terminal domain 261 383 1.0E-36 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Theos_1175 c38c559712c4348d724e5c4dbb35ed54 384 ProSitePatterns PS00737 Thiolases signature 2. 330 346 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Theos_1175 c38c559712c4348d724e5c4dbb35ed54 384 PIRSF PIRSF000429 1 384 1.1E-119 T 14-10-2018 IPR002155 Thiolase GO:0016747 Theos_1175 c38c559712c4348d724e5c4dbb35ed54 384 Gene3D G3DSA:3.40.47.10 127 381 4.8E-141 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1175 c38c559712c4348d724e5c4dbb35ed54 384 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 382 5.8E-126 T 14-10-2018 IPR002155 Thiolase GO:0016747 Theos_1175 c38c559712c4348d724e5c4dbb35ed54 384 SUPERFAMILY SSF53901 4 261 3.26E-75 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1175 c38c559712c4348d724e5c4dbb35ed54 384 SUPERFAMILY SSF53901 262 383 8.08E-39 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1175 c38c559712c4348d724e5c4dbb35ed54 384 Gene3D G3DSA:3.40.47.10 6 267 4.8E-141 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1175 c38c559712c4348d724e5c4dbb35ed54 384 Pfam PF00108 Thiolase, N-terminal domain 5 252 5.4E-66 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Theos_1586 f5ce39dc1202c460fafaa5225b585302 353 SMART SM00830 9 88 3.3E-28 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Theos_1586 f5ce39dc1202c460fafaa5225b585302 353 SUPERFAMILY SSF51569 60 349 1.47E-99 T 14-10-2018 Theos_1586 f5ce39dc1202c460fafaa5225b585302 353 TIGRFAM TIGR01801 CM_A: chorismate mutase 3 101 1.7E-34 T 14-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Theos_1586 f5ce39dc1202c460fafaa5225b585302 353 Gene3D G3DSA:1.20.59.10 1 90 5.2E-31 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Theos_1586 f5ce39dc1202c460fafaa5225b585302 353 Pfam PF00793 DAHP synthetase I family 114 346 1.2E-81 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Theos_1586 f5ce39dc1202c460fafaa5225b585302 353 Pfam PF01817 Chorismate mutase type II 9 86 3.8E-21 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Theos_1586 f5ce39dc1202c460fafaa5225b585302 353 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 94 348 6.7E-122 T 14-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Theos_1586 f5ce39dc1202c460fafaa5225b585302 353 Gene3D G3DSA:3.20.20.70 93 352 3.6E-99 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1586 f5ce39dc1202c460fafaa5225b585302 353 SUPERFAMILY SSF48600 4 87 9.16E-21 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Theos_1916 375848561e06bfc4ae151522debf758f 343 Gene3D G3DSA:3.40.50.300 9 320 7.1E-83 T 14-10-2018 Theos_1916 375848561e06bfc4ae151522debf758f 343 SUPERFAMILY SSF52540 1 314 2.86E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1916 375848561e06bfc4ae151522debf758f 343 Gene3D G3DSA:1.20.1050.90 116 288 7.1E-83 T 14-10-2018 Theos_1916 375848561e06bfc4ae151522debf758f 343 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 8 315 1.1E-62 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 Theos_1916 375848561e06bfc4ae151522debf758f 343 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 343 68.699 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 SUPERFAMILY SSF51735 1 257 5.93E-69 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 190 2.1E-5 T 14-10-2018 Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 Pfam PF00106 short chain dehydrogenase 6 194 4.3E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 Gene3D G3DSA:3.40.50.720 1 258 3.2E-68 T 14-10-2018 Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.4E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.4E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1077 91fbf18139540daf89efdfc2fa12ffdc 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.4E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1192 465fe570b06400040cd796dd5202d1fd 434 Pfam PF00919 Uncharacterized protein family UPF0004 3 91 1.3E-18 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Theos_1192 465fe570b06400040cd796dd5202d1fd 434 Gene3D G3DSA:3.40.50.12160 2 118 7.8E-27 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Theos_1192 465fe570b06400040cd796dd5202d1fd 434 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 431 1.2E-104 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Theos_1192 465fe570b06400040cd796dd5202d1fd 434 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 2 433 60.96 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Theos_1192 465fe570b06400040cd796dd5202d1fd 434 SMART SM00729 132 357 1.9E-52 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_1192 465fe570b06400040cd796dd5202d1fd 434 Pfam PF01938 TRAM domain 369 431 8.0E-6 T 14-10-2018 IPR002792 TRAM domain Theos_1192 465fe570b06400040cd796dd5202d1fd 434 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 3 431 1.3E-168 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Theos_1192 465fe570b06400040cd796dd5202d1fd 434 Gene3D G3DSA:2.40.50.140 372 434 4.7E-16 T 14-10-2018 Theos_1192 465fe570b06400040cd796dd5202d1fd 434 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 136 156 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Theos_1192 465fe570b06400040cd796dd5202d1fd 434 Gene3D G3DSA:3.80.30.20 130 371 2.9E-71 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Theos_1192 465fe570b06400040cd796dd5202d1fd 434 Pfam PF04055 Radical SAM superfamily 137 315 4.0E-28 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_1192 465fe570b06400040cd796dd5202d1fd 434 SUPERFAMILY SSF102114 118 363 2.75E-50 T 14-10-2018 Theos_1653 f222cad79de0b525ff6a1ab427db570d 326 SUPERFAMILY SSF159245 23 319 5.23E-50 T 14-10-2018 Theos_1653 f222cad79de0b525ff6a1ab427db570d 326 Pfam PF17186 Lipocalin-like domain 199 304 2.7E-23 T 14-10-2018 Theos_1653 f222cad79de0b525ff6a1ab427db570d 326 Gene3D G3DSA:2.40.370.10 198 320 1.2E-25 T 14-10-2018 IPR023374 AttH-like domain superfamily Theos_1653 f222cad79de0b525ff6a1ab427db570d 326 Pfam PF07143 CrtC N-terminal lipocalin domain 40 192 6.9E-15 T 14-10-2018 IPR010791 AttH domain Theos_1653 f222cad79de0b525ff6a1ab427db570d 326 Gene3D G3DSA:2.40.370.10 29 195 1.6E-13 T 14-10-2018 IPR023374 AttH-like domain superfamily Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 SUPERFAMILY SSF55347 145 316 3.27E-40 T 14-10-2018 Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 Gene3D G3DSA:3.30.360.10 143 316 1.5E-112 T 14-10-2018 Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 342 40.795 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 140 156 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 SUPERFAMILY SSF51735 1 158 1.19E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 SMART SM00859 3 137 7.4E-47 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 136 1.1E-27 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 348 4.3E-118 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 154 319 1.5E-15 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1218 8745bf9719c764f81dfe5a11d51d9953 348 Gene3D G3DSA:3.40.50.720 3 334 1.5E-112 T 14-10-2018 Theos_0939 a0ac2abe501c9e07111c66d4ca150cf2 492 SUPERFAMILY SSF109755 288 474 1.47E-18 T 14-10-2018 Theos_0939 a0ac2abe501c9e07111c66d4ca150cf2 492 Pfam PF02690 Na+/Pi-cotransporter 9 136 5.4E-8 T 14-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 Theos_0939 a0ac2abe501c9e07111c66d4ca150cf2 492 Pfam PF01895 PhoU domain 303 384 4.4E-5 T 14-10-2018 IPR026022 PhoU domain Theos_0939 a0ac2abe501c9e07111c66d4ca150cf2 492 Gene3D G3DSA:1.20.58.220 296 478 4.8E-7 T 14-10-2018 IPR038078 PhoU-like domain superfamily Theos_0109 eb98f19986913ec92e2262842d932b40 419 Gene3D G3DSA:1.20.810.10 1 414 2.9E-96 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 Theos_0109 eb98f19986913ec92e2262842d932b40 419 SUPERFAMILY SSF81648 224 372 2.34E-19 T 14-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 Theos_0109 eb98f19986913ec92e2262842d932b40 419 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 278 372 4.2E-7 T 14-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 Theos_0109 eb98f19986913ec92e2262842d932b40 419 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 97 272 1.4E-46 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 Theos_0109 eb98f19986913ec92e2262842d932b40 419 SUPERFAMILY SSF81342 3 267 8.32E-56 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 Theos_2087 d6badc7cc9eb41eec32da69f547b8430 63 Pfam PF12728 Helix-turn-helix domain 7 54 9.2E-14 T 14-10-2018 Theos_2087 d6badc7cc9eb41eec32da69f547b8430 63 Gene3D G3DSA:1.10.1660.10 4 54 9.4E-8 T 14-10-2018 Theos_2087 d6badc7cc9eb41eec32da69f547b8430 63 SUPERFAMILY SSF46955 6 52 1.04E-5 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_2087 d6badc7cc9eb41eec32da69f547b8430 63 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 52 1.6E-14 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 SMART SM00065 195 343 9.3E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 SMART SM00065 29 174 4.8E-20 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 SMART SM00471 360 494 1.7E-9 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 Gene3D G3DSA:3.30.450.40 172 348 1.3E-22 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 Pfam PF13185 GAF domain 29 164 2.6E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 Pfam PF13185 GAF domain 195 334 4.4E-15 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 Gene3D G3DSA:1.10.3210.10 349 527 1.4E-67 T 14-10-2018 Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 SUPERFAMILY SSF55781 160 335 6.32E-22 T 14-10-2018 Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 Gene3D G3DSA:3.30.450.40 10 171 8.7E-26 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 SUPERFAMILY SSF109604 350 525 2.48E-39 T 14-10-2018 Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 Pfam PF01966 HD domain 366 484 7.1E-21 T 14-10-2018 IPR006674 HD domain Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 TIGRFAM TIGR00277 HDIG: HDIG domain 364 452 2.4E-9 T 14-10-2018 IPR006675 HDIG domain Theos_0247 2609e610212d13f4e7309e8c1eddbfe6 528 SUPERFAMILY SSF55781 11 190 4.58E-25 T 14-10-2018 Theos_0686 26012893b8199536a5f92d839767d28a 854 SMART SM01086 757 846 1.0E-42 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Theos_0686 26012893b8199536a5f92d839767d28a 854 Gene3D G3DSA:3.40.50.300 539 755 1.1E-89 T 14-10-2018 Theos_0686 26012893b8199536a5f92d839767d28a 854 SMART SM00382 587 729 4.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0686 26012893b8199536a5f92d839767d28a 854 SMART SM00382 190 334 2.9E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0686 26012893b8199536a5f92d839767d28a 854 Gene3D G3DSA:3.40.50.300 334 534 8.5E-80 T 14-10-2018 Theos_0686 26012893b8199536a5f92d839767d28a 854 SUPERFAMILY SSF81923 4 148 1.86E-32 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Theos_0686 26012893b8199536a5f92d839767d28a 854 SUPERFAMILY SSF52540 536 839 8.78E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0686 26012893b8199536a5f92d839767d28a 854 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.7E-11 T 14-10-2018 IPR004176 Clp, N-terminal Theos_0686 26012893b8199536a5f92d839767d28a 854 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 136 2.8 T 14-10-2018 IPR004176 Clp, N-terminal Theos_0686 26012893b8199536a5f92d839767d28a 854 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 846 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 Theos_0686 26012893b8199536a5f92d839767d28a 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 2.2E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0686 26012893b8199536a5f92d839767d28a 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 665 683 2.2E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0686 26012893b8199536a5f92d839767d28a 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 636 654 2.2E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0686 26012893b8199536a5f92d839767d28a 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 698 712 2.2E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0686 26012893b8199536a5f92d839767d28a 854 SUPERFAMILY SSF52540 149 535 5.96E-100 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0686 26012893b8199536a5f92d839767d28a 854 Gene3D G3DSA:3.40.50.300 141 333 3.2E-76 T 14-10-2018 Theos_0686 26012893b8199536a5f92d839767d28a 854 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 621 639 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 Theos_0686 26012893b8199536a5f92d839767d28a 854 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 195 325 4.7E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_0686 26012893b8199536a5f92d839767d28a 854 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 757 837 1.5E-30 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Theos_0686 26012893b8199536a5f92d839767d28a 854 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 286 298 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 Theos_0686 26012893b8199536a5f92d839767d28a 854 Gene3D G3DSA:1.10.1780.10 1 140 4.3E-33 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Theos_0686 26012893b8199536a5f92d839767d28a 854 Gene3D G3DSA:1.10.8.60 757 854 1.2E-33 T 14-10-2018 Theos_0686 26012893b8199536a5f92d839767d28a 854 Pfam PF07724 AAA domain (Cdc48 subfamily) 586 751 2.7E-55 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_2325 1f15ec5dcc167e4db33cf447fd7e9bc0 226 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Theos_2325 1f15ec5dcc167e4db33cf447fd7e9bc0 226 Gene3D G3DSA:3.30.950.10 118 226 4.9E-34 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Theos_2325 1f15ec5dcc167e4db33cf447fd7e9bc0 226 SUPERFAMILY SSF53790 2 225 7.72E-65 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Theos_2325 1f15ec5dcc167e4db33cf447fd7e9bc0 226 Gene3D G3DSA:3.40.1010.10 3 117 1.3E-44 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Theos_2325 1f15ec5dcc167e4db33cf447fd7e9bc0 226 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 204 1.3E-45 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Theos_2325 1f15ec5dcc167e4db33cf447fd7e9bc0 226 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 225 1.4E-63 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Theos_0748 2c813110be9d872e8bf6161ea8f2609d 146 Gene3D G3DSA:3.40.250.10 47 146 4.4E-31 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0748 2c813110be9d872e8bf6161ea8f2609d 146 SMART SM00450 49 143 6.5E-29 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0748 2c813110be9d872e8bf6161ea8f2609d 146 Pfam PF00581 Rhodanese-like domain 51 140 4.1E-20 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0748 2c813110be9d872e8bf6161ea8f2609d 146 SUPERFAMILY SSF52821 41 146 2.62E-33 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0415 2e888059e04881d84f77bef4c57d7f1b 316 Gene3D G3DSA:3.40.50.2300 1 131 7.5E-40 T 14-10-2018 Theos_0415 2e888059e04881d84f77bef4c57d7f1b 316 Pfam PF00072 Response regulator receiver domain 3 112 7.5E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0415 2e888059e04881d84f77bef4c57d7f1b 316 Gene3D G3DSA:1.10.3210.10 132 311 2.8E-55 T 14-10-2018 Theos_0415 2e888059e04881d84f77bef4c57d7f1b 316 SMART SM00471 142 275 2.5E-11 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0415 2e888059e04881d84f77bef4c57d7f1b 316 SUPERFAMILY SSF109604 135 304 9.2E-36 T 14-10-2018 Theos_0415 2e888059e04881d84f77bef4c57d7f1b 316 Pfam PF01966 HD domain 148 265 3.6E-13 T 14-10-2018 IPR006674 HD domain Theos_0415 2e888059e04881d84f77bef4c57d7f1b 316 SUPERFAMILY SSF52172 1 134 1.05E-42 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0415 2e888059e04881d84f77bef4c57d7f1b 316 TIGRFAM TIGR00277 HDIG: HDIG domain 149 237 4.3E-8 T 14-10-2018 IPR006675 HDIG domain Theos_0415 2e888059e04881d84f77bef4c57d7f1b 316 SMART SM00448 1 112 6.0E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0491 fe6f191856173eebcccb042baa92c6c3 303 Gene3D G3DSA:2.70.70.10 149 300 3.2E-43 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_0491 fe6f191856173eebcccb042baa92c6c3 303 Pfam PF01476 LysM domain 1 41 6.9E-15 T 14-10-2018 IPR018392 LysM domain Theos_0491 fe6f191856173eebcccb042baa92c6c3 303 Pfam PF01551 Peptidase family M23 199 293 9.7E-28 T 14-10-2018 IPR016047 Peptidase M23 Theos_0491 fe6f191856173eebcccb042baa92c6c3 303 SMART SM00257 1 42 2.5E-13 T 14-10-2018 IPR018392 LysM domain Theos_0491 fe6f191856173eebcccb042baa92c6c3 303 SUPERFAMILY SSF51261 145 296 1.1E-46 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_0491 fe6f191856173eebcccb042baa92c6c3 303 SUPERFAMILY SSF54106 1 41 3.66E-10 T 14-10-2018 Theos_0491 fe6f191856173eebcccb042baa92c6c3 303 Gene3D G3DSA:3.10.350.10 1 42 8.2E-17 T 14-10-2018 IPR036779 LysM domain superfamily Theos_0488 f6db20820374284786d8444688cf934a 804 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 751 2.2E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Theos_0488 f6db20820374284786d8444688cf934a 804 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 499 543 1.1E-9 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Theos_0488 f6db20820374284786d8444688cf934a 804 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 547 596 2.9E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Theos_0488 f6db20820374284786d8444688cf934a 804 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 651 698 1.3E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Theos_0488 f6db20820374284786d8444688cf934a 804 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 604 647 2.3E-11 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Theos_0488 f6db20820374284786d8444688cf934a 804 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 756 801 7.2E-14 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Theos_0488 f6db20820374284786d8444688cf934a 804 SUPERFAMILY SSF56719 26 479 7.19E-170 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Theos_0488 f6db20820374284786d8444688cf934a 804 Gene3D G3DSA:1.10.268.10 363 452 4.5E-203 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Theos_0488 f6db20820374284786d8444688cf934a 804 SUPERFAMILY SSF101904 492 803 9.68E-95 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Theos_0488 f6db20820374284786d8444688cf934a 804 Gene3D G3DSA:3.90.199.10 28 478 4.5E-203 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 Theos_0488 f6db20820374284786d8444688cf934a 804 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 457 4.8E-154 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Theos_0488 f6db20820374284786d8444688cf934a 804 SMART SM00434 7 458 2.9E-263 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Theos_0488 f6db20820374284786d8444688cf934a 804 Gene3D G3DSA:3.30.1360.40 231 326 4.5E-203 T 14-10-2018 Theos_0488 f6db20820374284786d8444688cf934a 804 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 803 23.502 T 14-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Theos_0488 f6db20820374284786d8444688cf934a 804 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 5 798 0.0 T 14-10-2018 Theos_0488 f6db20820374284786d8444688cf934a 804 Gene3D G3DSA:2.120.10.90 490 801 1.0E-111 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 43 176 1.5E-23 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 195 211 2.0E-5 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 TIGRFAM TIGR01083 nth: endonuclease III 13 202 1.9E-78 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 SMART SM00478 47 193 1.2E-54 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 SMART SM00525 194 214 2.1E-5 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 ProSitePatterns PS01155 Endonuclease III family signature. 111 139 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 Gene3D G3DSA:1.10.340.30 30 140 1.1E-75 T 14-10-2018 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 Gene3D G3DSA:1.10.1670.10 20 211 1.1E-75 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 SUPERFAMILY SSF48150 12 214 2.98E-70 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 PIRSF PIRSF001435 7 216 4.8E-50 T 14-10-2018 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 195 211 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 Theos_1750 1de79e905dff81d1b69ea13d8ece747c 217 Hamap MF_00942 Endonuclease III [nth]. 8 217 38.68 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Theos_2011 9a99ecf8b7bd4da7301a25378d301820 209 Pfam PF00149 Calcineurin-like phosphoesterase 27 177 5.1E-4 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Theos_2011 9a99ecf8b7bd4da7301a25378d301820 209 SUPERFAMILY SSF56300 2 176 4.85E-20 T 14-10-2018 Theos_2011 9a99ecf8b7bd4da7301a25378d301820 209 Gene3D G3DSA:3.60.21.10 58 177 6.0E-6 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_0468 dbdbd31153fb8b978080e79a8953ee80 372 Pfam PF03275 UDP-galactopyranose mutase 151 352 7.5E-76 T 14-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 Theos_0468 dbdbd31153fb8b978080e79a8953ee80 372 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 4 369 7.5E-132 T 14-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 Theos_0468 dbdbd31153fb8b978080e79a8953ee80 372 SUPERFAMILY SSF51971 2 369 2.94E-50 T 14-10-2018 Theos_0468 dbdbd31153fb8b978080e79a8953ee80 372 Gene3D G3DSA:3.40.50.720 280 371 2.2E-19 T 14-10-2018 Theos_0468 dbdbd31153fb8b978080e79a8953ee80 372 Gene3D G3DSA:3.40.50.720 1 85 1.7E-33 T 14-10-2018 Theos_0468 dbdbd31153fb8b978080e79a8953ee80 372 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 73 2.0E-15 T 14-10-2018 Theos_0468 dbdbd31153fb8b978080e79a8953ee80 372 SUPERFAMILY SSF54373 250 319 2.94E-19 T 14-10-2018 Theos_0468 dbdbd31153fb8b978080e79a8953ee80 372 Gene3D G3DSA:3.40.50.720 166 278 7.4E-29 T 14-10-2018 Theos_1449 728124c51926686c39de7de7062d15db 207 SUPERFAMILY SSF51735 2 200 7.8E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1449 728124c51926686c39de7de7062d15db 207 Gene3D G3DSA:3.40.50.720 1 203 4.8E-49 T 14-10-2018 Theos_1449 728124c51926686c39de7de7062d15db 207 Pfam PF00106 short chain dehydrogenase 3 173 3.1E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1449 728124c51926686c39de7de7062d15db 207 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 153 3.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1449 728124c51926686c39de7de7062d15db 207 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 76 3.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1449 728124c51926686c39de7de7062d15db 207 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1449 728124c51926686c39de7de7062d15db 207 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 121 149 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Pfam PF12838 4Fe-4S dicluster domain 685 752 8.2E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 955 1066 5.9E-10 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Gene3D G3DSA:3.40.920.10 412 620 3.3E-72 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Gene3D G3DSA:3.40.50.970 2 256 1.8E-103 T 14-10-2018 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 SUPERFAMILY SSF52518 1 256 4.12E-70 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Gene3D G3DSA:3.30.70.20 665 786 6.8E-35 T 14-10-2018 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 SUPERFAMILY SSF52922 258 408 6.0E-43 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 SUPERFAMILY SSF54862 661 833 1.11E-20 T 14-10-2018 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Pfam PF10371 Domain of unknown function 625 674 2.2E-21 T 14-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 245 3.9E-74 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 685 696 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 267 349 3.1E-12 T 14-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 SMART SM00890 618 675 4.4E-30 T 14-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 5 1159 0.0 T 14-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Gene3D G3DSA:3.40.50.920 257 410 6.0E-51 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Gene3D G3DSA:3.40.50.970 791 1162 4.7E-144 T 14-10-2018 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 740 751 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 422 606 2.1E-28 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 SUPERFAMILY SSF53323 414 664 8.37E-73 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 SUPERFAMILY SSF52518 791 1161 7.0E-120 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 Gene3D G3DSA:4.10.780.10 625 664 6.0E-8 T 14-10-2018 IPR037112 Pyruvate-flavodoxin oxidoreductase, EKR domain superfamily Theos_1518 b326e3cb86b7f76e229c54bf0148eb12 1165 PIRSF PIRSF000159 1 1165 0.0 T 14-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 Theos_2454 902b6112e8e98cb491419f99d051f371 326 Gene3D G3DSA:3.90.1200.10 104 314 2.7E-46 T 14-10-2018 Theos_2454 902b6112e8e98cb491419f99d051f371 326 SUPERFAMILY SSF56112 2 316 7.9E-46 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Theos_2454 902b6112e8e98cb491419f99d051f371 326 Pfam PF01636 Phosphotransferase enzyme family 21 250 1.2E-33 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase Theos_2454 902b6112e8e98cb491419f99d051f371 326 Gene3D G3DSA:3.30.200.20 1 101 1.0E-5 T 14-10-2018 Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 Gene3D G3DSA:3.40.50.300 4 168 1.4E-43 T 14-10-2018 Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 SUPERFAMILY SSF46785 243 317 6.22E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 3 222 9.6E-105 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 Gene3D G3DSA:1.10.8.60 169 243 8.4E-28 T 14-10-2018 Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 324 157.983 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 9 313 4.1E-142 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 241 313 1.4E-32 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 313 1.0E-24 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 SUPERFAMILY SSF52540 6 236 3.42E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 Gene3D G3DSA:1.10.10.10 244 324 4.2E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0662 c35e86afeddfa5dbdde13b2d33843b06 324 SMART SM00382 37 169 5.0E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0804 9bf6f8020983fb62960f55f052d684ad 333 Pfam PF07907 YibE/F-like protein 79 317 5.1E-67 T 14-10-2018 IPR012507 YibE/F-like Theos_1971 cfed0586588796cd2524a317e546dde3 363 SUPERFAMILY SSF52540 8 338 2.75E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1971 cfed0586588796cd2524a317e546dde3 363 Pfam PF00437 Type II/IV secretion system protein 17 272 1.6E-42 T 14-10-2018 IPR001482 Type II/IV secretion system protein Theos_1971 cfed0586588796cd2524a317e546dde3 363 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 7 348 8.5E-154 T 14-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 Theos_1971 cfed0586588796cd2524a317e546dde3 363 Gene3D G3DSA:3.30.450.90 2 103 2.4E-35 T 14-10-2018 Theos_1971 cfed0586588796cd2524a317e546dde3 363 Gene3D G3DSA:3.40.50.300 105 359 2.8E-100 T 14-10-2018 Theos_1971 cfed0586588796cd2524a317e546dde3 363 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 197 211 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Theos_1971 cfed0586588796cd2524a317e546dde3 363 SMART SM00382 126 251 0.0013 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1969 478672537dddece2a33d1da170a312cc 161 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 3 152 1.3E-33 T 14-10-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like Theos_1969 478672537dddece2a33d1da170a312cc 161 SUPERFAMILY SSF56784 11 132 1.48E-19 T 14-10-2018 IPR036412 HAD-like superfamily Theos_1969 478672537dddece2a33d1da170a312cc 161 Gene3D G3DSA:3.40.50.1000 24 148 1.4E-15 T 14-10-2018 IPR023214 HAD superfamily Theos_1969 478672537dddece2a33d1da170a312cc 161 Pfam PF13242 HAD-hyrolase-like 93 131 9.0E-8 T 14-10-2018 Theos_1410 669b230f24737ab5e14e7b8d6e8d8eb7 323 SMART SM00388 112 179 0.0078 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_1410 669b230f24737ab5e14e7b8d6e8d8eb7 323 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 223 318 5.1E-12 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1410 669b230f24737ab5e14e7b8d6e8d8eb7 323 Gene3D G3DSA:1.10.287.130 57 180 7.3E-12 T 14-10-2018 Theos_1410 669b230f24737ab5e14e7b8d6e8d8eb7 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 299 4.7E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1410 669b230f24737ab5e14e7b8d6e8d8eb7 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 251 265 4.7E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1410 669b230f24737ab5e14e7b8d6e8d8eb7 323 Gene3D G3DSA:3.30.565.10 181 320 3.5E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1410 669b230f24737ab5e14e7b8d6e8d8eb7 323 SUPERFAMILY SSF47384 96 179 5.49E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_1410 669b230f24737ab5e14e7b8d6e8d8eb7 323 SMART SM00387 220 321 6.7E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1410 669b230f24737ab5e14e7b8d6e8d8eb7 323 SUPERFAMILY SSF55874 184 317 8.64E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0770 d60562207b657676348bff85207e0598 507 Gene3D G3DSA:3.30.930.10 3 112 2.0E-30 T 14-10-2018 Theos_0770 d60562207b657676348bff85207e0598 507 Gene3D G3DSA:3.30.930.10 128 376 1.1E-98 T 14-10-2018 Theos_0770 d60562207b657676348bff85207e0598 507 SUPERFAMILY SSF55681 6 405 1.14E-124 T 14-10-2018 Theos_0770 d60562207b657676348bff85207e0598 507 PRINTS PR01043 Glycyl-tRNA synthetase signature 235 245 3.7E-59 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_0770 d60562207b657676348bff85207e0598 507 PRINTS PR01043 Glycyl-tRNA synthetase signature 165 177 3.7E-59 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_0770 d60562207b657676348bff85207e0598 507 PRINTS PR01043 Glycyl-tRNA synthetase signature 218 235 3.7E-59 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_0770 d60562207b657676348bff85207e0598 507 PRINTS PR01043 Glycyl-tRNA synthetase signature 186 203 3.7E-59 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_0770 d60562207b657676348bff85207e0598 507 PRINTS PR01043 Glycyl-tRNA synthetase signature 357 369 3.7E-59 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_0770 d60562207b657676348bff85207e0598 507 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 3.7E-59 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_0770 d60562207b657676348bff85207e0598 507 PRINTS PR01043 Glycyl-tRNA synthetase signature 442 461 3.7E-59 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_0770 d60562207b657676348bff85207e0598 507 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 185 375 6.2E-11 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_0770 d60562207b657676348bff85207e0598 507 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 506 49.46 T 14-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 Theos_0770 d60562207b657676348bff85207e0598 507 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 262 3.0E-79 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_0770 d60562207b657676348bff85207e0598 507 Gene3D G3DSA:3.40.50.800 395 506 4.5E-36 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily Theos_0770 d60562207b657676348bff85207e0598 507 Pfam PF03129 Anticodon binding domain 402 504 1.7E-27 T 14-10-2018 IPR004154 Anticodon-binding Theos_0770 d60562207b657676348bff85207e0598 507 SUPERFAMILY SSF52954 398 505 5.29E-28 T 14-10-2018 Theos_0617 3e88079b28698729ae599c18b3b02498 405 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 88 102 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Theos_0617 3e88079b28698729ae599c18b3b02498 405 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 14 399 5.0E-183 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Theos_0617 3e88079b28698729ae599c18b3b02498 405 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 9 401 53.296 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Theos_0617 3e88079b28698729ae599c18b3b02498 405 SUPERFAMILY SSF53686 10 399 5.89E-148 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Theos_0617 3e88079b28698729ae599c18b3b02498 405 PIRSF PIRSF001413 2 405 1.3E-159 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Theos_0617 3e88079b28698729ae599c18b3b02498 405 Gene3D G3DSA:3.40.50.1100 61 394 1.2E-181 T 14-10-2018 Theos_0617 3e88079b28698729ae599c18b3b02498 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 59 388 1.5E-49 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Theos_0617 3e88079b28698729ae599c18b3b02498 405 Gene3D G3DSA:3.40.50.1100 17 213 1.2E-181 T 14-10-2018 Theos_1866 2c6c2f5e77771189f717c5182650db80 125 PIRSF PIRSF006614 1 124 2.2E-52 T 14-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 Theos_1866 2c6c2f5e77771189f717c5182650db80 125 SUPERFAMILY SSF52335 4 120 7.85E-47 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Theos_1866 2c6c2f5e77771189f717c5182650db80 125 ProSitePatterns PS01335 Methylglyoxal synthase active site. 55 63 - T 14-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 Theos_1866 2c6c2f5e77771189f717c5182650db80 125 Gene3D G3DSA:3.40.50.1380 1 125 9.4E-54 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Theos_1866 2c6c2f5e77771189f717c5182650db80 125 Pfam PF02142 MGS-like domain 16 108 8.8E-15 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain Theos_1866 2c6c2f5e77771189f717c5182650db80 125 SMART SM00851 15 108 1.4E-20 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain Theos_1866 2c6c2f5e77771189f717c5182650db80 125 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 3 117 1.3E-51 T 14-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 Theos_1866 2c6c2f5e77771189f717c5182650db80 125 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 2 121 31.814 T 14-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 Theos_1390 928e927fad83c7ebb4fbdcb2993fbe15 196 Pfam PF04260 Protein of unknown function (DUF436) 8 179 2.5E-65 T 14-10-2018 IPR006340 Protein of unknown function DUF436 Theos_1390 928e927fad83c7ebb4fbdcb2993fbe15 196 Gene3D G3DSA:3.40.50.10360 1 196 5.5E-82 T 14-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like Theos_1390 928e927fad83c7ebb4fbdcb2993fbe15 196 Hamap MF_00800 UPF0340 protein . 1 196 78.722 T 14-10-2018 IPR006340 Protein of unknown function DUF436 Theos_1390 928e927fad83c7ebb4fbdcb2993fbe15 196 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 11 179 4.1E-57 T 14-10-2018 IPR006340 Protein of unknown function DUF436 Theos_1390 928e927fad83c7ebb4fbdcb2993fbe15 196 SUPERFAMILY SSF110710 1 189 3.4E-71 T 14-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like Theos_1390 928e927fad83c7ebb4fbdcb2993fbe15 196 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 11 191 1.0E-72 T 14-10-2018 IPR006340 Protein of unknown function DUF436 Theos_0343 90e0f471bcc74ebd6266ead4f6adc890 126 Gene3D G3DSA:3.30.450.30 1 125 9.0E-11 T 14-10-2018 Theos_0343 90e0f471bcc74ebd6266ead4f6adc890 126 SUPERFAMILY SSF103196 2 121 1.01E-11 T 14-10-2018 Theos_2199 dc9acc5547a3cb6acdd4e25949084889 210 SUPERFAMILY SSF51695 1 209 1.3E-51 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Theos_2199 dc9acc5547a3cb6acdd4e25949084889 210 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 58 1.7E-17 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Theos_2199 dc9acc5547a3cb6acdd4e25949084889 210 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 69 207 4.0E-10 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Theos_2199 dc9acc5547a3cb6acdd4e25949084889 210 Gene3D G3DSA:3.20.20.190 1 210 6.8E-60 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Theos_0410 90209429c9d58841111dcb3d31ba7a81 230 SMART SM00450 117 227 6.2E-18 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0410 90209429c9d58841111dcb3d31ba7a81 230 SMART SM00450 1 105 0.081 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0410 90209429c9d58841111dcb3d31ba7a81 230 Pfam PF00581 Rhodanese-like domain 124 223 2.3E-9 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0410 90209429c9d58841111dcb3d31ba7a81 230 Pfam PF00581 Rhodanese-like domain 7 83 1.3E-9 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0410 90209429c9d58841111dcb3d31ba7a81 230 SUPERFAMILY SSF52821 120 229 1.44E-23 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0410 90209429c9d58841111dcb3d31ba7a81 230 SUPERFAMILY SSF52821 5 97 3.8E-12 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0410 90209429c9d58841111dcb3d31ba7a81 230 Gene3D G3DSA:3.40.250.10 119 229 2.1E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0410 90209429c9d58841111dcb3d31ba7a81 230 ProSitePatterns PS00380 Rhodanese signature 1. 18 29 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 Theos_0410 90209429c9d58841111dcb3d31ba7a81 230 Gene3D G3DSA:3.40.250.10 1 118 2.3E-24 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0813 168123c9d25b9b06706627bd75844ee6 73 Pfam PF11609 Protein of unknown function (DUF3248) 11 73 5.6E-34 T 14-10-2018 IPR021650 Protein of unknown function DUF3248 Theos_0813 168123c9d25b9b06706627bd75844ee6 73 Gene3D G3DSA:3.10.20.570 7 73 1.5E-34 T 14-10-2018 Theos_2258 b3a7c6528da5027e7a965c6a528847b7 175 Pfam PF13551 Winged helix-turn helix 38 95 1.0E-10 T 14-10-2018 Theos_2258 b3a7c6528da5027e7a965c6a528847b7 175 SUPERFAMILY SSF46689 35 144 8.24E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_2258 b3a7c6528da5027e7a965c6a528847b7 175 Pfam PF13592 Winged helix-turn helix 111 168 1.4E-16 T 14-10-2018 IPR025959 Winged helix-turn helix domain Theos_2015 17a0d6eb55baa968ae9b8cfc8d989cfb 116 SUPERFAMILY SSF54913 1 112 2.8E-37 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Theos_2015 17a0d6eb55baa968ae9b8cfc8d989cfb 116 Gene3D G3DSA:3.30.70.120 1 116 6.6E-43 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Theos_2015 17a0d6eb55baa968ae9b8cfc8d989cfb 116 PRINTS PR00340 P-II protein signature 23 41 2.6E-23 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Theos_2015 17a0d6eb55baa968ae9b8cfc8d989cfb 116 PRINTS PR00340 P-II protein signature 2 17 2.6E-23 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Theos_2015 17a0d6eb55baa968ae9b8cfc8d989cfb 116 PRINTS PR00340 P-II protein signature 52 75 2.6E-23 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Theos_2015 17a0d6eb55baa968ae9b8cfc8d989cfb 116 PRINTS PR00340 P-II protein signature 83 103 2.6E-23 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Theos_2015 17a0d6eb55baa968ae9b8cfc8d989cfb 116 SMART SM00938 4 105 9.7E-44 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Theos_2015 17a0d6eb55baa968ae9b8cfc8d989cfb 116 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.1E-34 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Theos_2015 17a0d6eb55baa968ae9b8cfc8d989cfb 116 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 Theos_0262 527177b0c69f47de8a46a52513e52605 276 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 79 6.7E-8 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Theos_0262 527177b0c69f47de8a46a52513e52605 276 Hamap MF_00158 Pantothenate synthetase [panC]. 2 274 40.035 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 Theos_0262 527177b0c69f47de8a46a52513e52605 276 SUPERFAMILY SSF52374 5 274 1.2E-100 T 14-10-2018 Theos_0262 527177b0c69f47de8a46a52513e52605 276 Gene3D G3DSA:3.40.50.620 2 172 1.4E-77 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0262 527177b0c69f47de8a46a52513e52605 276 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 17 274 1.6E-93 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 Theos_0262 527177b0c69f47de8a46a52513e52605 276 Pfam PF02569 Pantoate-beta-alanine ligase 4 272 9.8E-98 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 Theos_0262 527177b0c69f47de8a46a52513e52605 276 Gene3D G3DSA:3.30.1300.10 173 276 2.6E-28 T 14-10-2018 Theos_0404 1052add0fac51db272ef2c590dad41f9 326 SUPERFAMILY SSF53850 21 312 3.63E-63 T 14-10-2018 Theos_0404 1052add0fac51db272ef2c590dad41f9 326 PIRSF PIRSF002825 12 326 2.3E-79 T 14-10-2018 IPR026045 Ferric binding protein Theos_0404 1052add0fac51db272ef2c590dad41f9 326 Pfam PF13531 Bacterial extracellular solute-binding protein 22 275 2.0E-21 T 14-10-2018 Theos_0404 1052add0fac51db272ef2c590dad41f9 326 Gene3D G3DSA:3.40.190.10 22 294 5.3E-112 T 14-10-2018 Theos_0404 1052add0fac51db272ef2c590dad41f9 326 Gene3D G3DSA:3.40.190.10 116 308 5.3E-112 T 14-10-2018 Theos_1641 a517a29a991662251e4922990192ad43 436 SUPERFAMILY SSF51905 3 363 3.31E-25 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1641 a517a29a991662251e4922990192ad43 436 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 3 428 7.9E-186 T 14-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 Theos_1641 a517a29a991662251e4922990192ad43 436 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 334 357 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Theos_1641 a517a29a991662251e4922990192ad43 436 Pfam PF01134 Glucose inhibited division protein A 4 363 2.2E-104 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 Theos_1641 a517a29a991662251e4922990192ad43 436 Gene3D G3DSA:3.50.50.60 1 182 3.0E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1641 a517a29a991662251e4922990192ad43 436 Gene3D G3DSA:3.50.50.60 287 435 2.5E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1641 a517a29a991662251e4922990192ad43 436 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 4 429 34.292 T 14-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 Theos_2183 3dce9121d6b95a4a2a5683b176260807 164 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 143 3.5E-34 T 14-10-2018 IPR001453 MoaB/Mog domain Theos_2183 3dce9121d6b95a4a2a5683b176260807 164 SMART SM00852 5 149 2.4E-30 T 14-10-2018 IPR001453 MoaB/Mog domain Theos_2183 3dce9121d6b95a4a2a5683b176260807 164 Gene3D G3DSA:3.40.980.10 1 161 9.4E-59 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Theos_2183 3dce9121d6b95a4a2a5683b176260807 164 SUPERFAMILY SSF53218 2 153 2.36E-47 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Theos_2183 3dce9121d6b95a4a2a5683b176260807 164 Pfam PF00994 Probable molybdopterin binding domain 5 148 1.5E-34 T 14-10-2018 IPR001453 MoaB/Mog domain Theos_2183 3dce9121d6b95a4a2a5683b176260807 164 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 65 78 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 Theos_0853 50576e1a8d6d70b56b131287640004f3 277 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 257 4.6E-27 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_1669 8256ea8dc9970fed62c5afcc6bb055dc 128 Pfam PF00380 Ribosomal protein S9/S16 8 128 4.2E-43 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 Theos_1669 8256ea8dc9970fed62c5afcc6bb055dc 128 SUPERFAMILY SSF54211 3 128 2.01E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_1669 8256ea8dc9970fed62c5afcc6bb055dc 128 Gene3D G3DSA:3.30.230.10 1 128 1.4E-52 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_1669 8256ea8dc9970fed62c5afcc6bb055dc 128 ProSitePatterns PS00360 Ribosomal protein S9 signature. 67 85 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 Theos_1669 8256ea8dc9970fed62c5afcc6bb055dc 128 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 128 31.566 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 23 128 4.3E-12 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 157 458 4.9E-118 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 PRINTS PR00481 Cytosol aminopeptidase signature 253 274 1.7E-48 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 PRINTS PR00481 Cytosol aminopeptidase signature 290 311 1.7E-48 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 PRINTS PR00481 Cytosol aminopeptidase signature 312 332 1.7E-48 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 PRINTS PR00481 Cytosol aminopeptidase signature 340 355 1.7E-48 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 PRINTS PR00481 Cytosol aminopeptidase signature 231 248 1.7E-48 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 SUPERFAMILY SSF53187 152 462 6.59E-108 T 14-10-2018 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 Gene3D G3DSA:3.40.220.10 3 141 4.2E-18 T 14-10-2018 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 SUPERFAMILY SSF52949 20 155 1.29E-18 T 14-10-2018 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 Gene3D G3DSA:3.40.630.10 142 465 1.3E-129 T 14-10-2018 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 316 323 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Theos_1908 08782d0615be37627e13d0d2c1802aa3 465 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 465 33.008 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 Theos_1290 42f9d793cd3fa0409583449eb81dd018 346 SUPERFAMILY SSF51735 2 146 1.2E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1290 42f9d793cd3fa0409583449eb81dd018 346 SUPERFAMILY SSF55347 134 283 4.09E-22 T 14-10-2018 Theos_1290 42f9d793cd3fa0409583449eb81dd018 346 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 199 4.0E-7 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 Theos_1290 42f9d793cd3fa0409583449eb81dd018 346 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 113 3.7E-22 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Theos_1290 42f9d793cd3fa0409583449eb81dd018 346 Gene3D G3DSA:3.40.50.720 1 132 1.1E-32 T 14-10-2018 Theos_1290 42f9d793cd3fa0409583449eb81dd018 346 Gene3D G3DSA:3.30.360.10 133 343 1.2E-36 T 14-10-2018 Theos_0442 024cf5c211627233f730b3636cf1e0a3 434 TIGRFAM TIGR00277 HDIG: HDIG domain 221 316 9.0E-8 T 14-10-2018 IPR006675 HDIG domain Theos_0442 024cf5c211627233f730b3636cf1e0a3 434 SMART SM00471 219 357 2.2E-12 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0442 024cf5c211627233f730b3636cf1e0a3 434 SUPERFAMILY SSF109604 212 387 2.66E-37 T 14-10-2018 Theos_0442 024cf5c211627233f730b3636cf1e0a3 434 Gene3D G3DSA:1.10.3210.10 198 391 2.7E-68 T 14-10-2018 Theos_0442 024cf5c211627233f730b3636cf1e0a3 434 Pfam PF01966 HD domain 226 348 7.0E-22 T 14-10-2018 IPR006674 HD domain Theos_0198 9407acc34ec04d07c618a5ea3016e68f 98 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 85 16.236 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0198 9407acc34ec04d07c618a5ea3016e68f 98 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 65 5.4E-14 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0198 9407acc34ec04d07c618a5ea3016e68f 98 Gene3D G3DSA:1.10.20.50 46 89 2.6E-27 T 14-10-2018 Theos_0198 9407acc34ec04d07c618a5ea3016e68f 98 SUPERFAMILY SSF143800 1 95 2.55E-18 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0198 9407acc34ec04d07c618a5ea3016e68f 98 Gene3D G3DSA:2.20.150.30 1 45 7.8E-26 T 14-10-2018 Theos_0198 9407acc34ec04d07c618a5ea3016e68f 98 Pfam PF00830 Ribosomal L28 family 3 65 1.3E-11 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 SUPERFAMILY SSF51735 3 237 6.29E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 65 76 5.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 5.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 5.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 Pfam PF00106 short chain dehydrogenase 5 192 1.3E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 76 1.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 1.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1174 72ca46f2cc8f73823eeb8403c714076d 242 Gene3D G3DSA:3.40.50.720 1 240 9.5E-72 T 14-10-2018 Theos_1873 84c7fcbeee5a34ed7af8e69c5150e9b2 69 Pfam PF09360 Iron-binding zinc finger CDGSH type 8 53 1.2E-15 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 Theos_1873 84c7fcbeee5a34ed7af8e69c5150e9b2 69 SMART SM00704 21 58 2.3E-7 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 Theos_1873 84c7fcbeee5a34ed7af8e69c5150e9b2 69 Gene3D G3DSA:3.40.5.90 1 66 2.2E-18 T 14-10-2018 Theos_1126 aad0d1a5948e8612517ea30129b04f1d 353 Pfam PF01098 Cell cycle protein 34 342 1.4E-58 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_2083 bc828ee16d394cc471d7395c3c24f704 318 Pfam PF13362 Toprim domain 223 307 1.4E-16 T 14-10-2018 IPR006171 TOPRIM domain Theos_1255 abc63d94eba93b1c953b1e6db92c6d09 557 Pfam PF00920 Dehydratase family 31 549 1.1E-197 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Theos_1255 abc63d94eba93b1c953b1e6db92c6d09 557 SUPERFAMILY SSF52016 374 551 4.08E-60 T 14-10-2018 Theos_1255 abc63d94eba93b1c953b1e6db92c6d09 557 Gene3D G3DSA:3.50.30.80 374 523 5.3E-53 T 14-10-2018 Theos_1255 abc63d94eba93b1c953b1e6db92c6d09 557 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 552 44.265 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Theos_1255 abc63d94eba93b1c953b1e6db92c6d09 557 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Theos_1255 abc63d94eba93b1c953b1e6db92c6d09 557 SUPERFAMILY SSF143975 1 373 1.16E-123 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Theos_1255 abc63d94eba93b1c953b1e6db92c6d09 557 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 460 471 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Theos_1255 abc63d94eba93b1c953b1e6db92c6d09 557 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 551 4.3E-202 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 384 399 1.7E-28 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 550 559 1.7E-28 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 510 523 1.7E-28 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 225 248 1.7E-28 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 1.7E-28 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 627 1.4E-180 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1037 14.131 T 14-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 Gene3D G3DSA:3.90.740.10 196 390 6.3E-264 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 Pfam PF08264 Anticodon-binding domain of tRNA 677 828 6.2E-33 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 Gene3D G3DSA:3.40.50.620 14 617 6.3E-264 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 SUPERFAMILY SSF52374 7 640 1.08E-141 T 14-10-2018 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 8 827 4.6E-288 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 SUPERFAMILY SSF50677 203 380 1.88E-48 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 Gene3D G3DSA:1.10.730.10 631 821 1.3E-61 T 14-10-2018 Theos_1466 39b29ffc8dcf760675655f02b8282be2 1042 SUPERFAMILY SSF47323 645 890 6.92E-56 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1400 5dcc254e7b42b712e44db4159c8b76bb 471 Pfam PF01425 Amidase 19 448 2.6E-139 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Theos_1400 5dcc254e7b42b712e44db4159c8b76bb 471 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 6 459 88.243 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Theos_1400 5dcc254e7b42b712e44db4159c8b76bb 471 SUPERFAMILY SSF75304 3 458 6.15E-153 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Theos_1400 5dcc254e7b42b712e44db4159c8b76bb 471 ProSitePatterns PS00571 Amidases signature. 139 170 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 Theos_1400 5dcc254e7b42b712e44db4159c8b76bb 471 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 7 458 9.8E-162 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Theos_1400 5dcc254e7b42b712e44db4159c8b76bb 471 Gene3D G3DSA:3.90.1300.10 1 471 2.8E-207 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 63 109 2.3E-20 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 72 92 8.2E-8 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 405 427 8.2E-8 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 345 367 8.2E-8 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 145 166 2.2E-59 T 14-10-2018 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 70 95 2.2E-59 T 14-10-2018 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 98 118 2.2E-59 T 14-10-2018 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 406 425 2.2E-59 T 14-10-2018 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 212 233 2.2E-59 T 14-10-2018 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 234 260 2.2E-59 T 14-10-2018 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 302 314 2.2E-59 T 14-10-2018 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 605 2.1E-194 T 14-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0705 6892c4189c5a0dbe144b7d5fb65e0348 607 Pfam PF00361 Proton-conducting membrane transporter 125 395 9.5E-82 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 Gene3D G3DSA:2.20.25.90 1 53 7.7E-7 T 14-10-2018 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 Gene3D G3DSA:3.30.2070.10 431 514 3.4E-129 T 14-10-2018 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 Pfam PF01568 Molydopterin dinucleotide binding domain 548 658 3.6E-25 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 SUPERFAMILY SSF53706 2 560 3.14E-152 T 14-10-2018 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 SMART SM00926 1 53 6.0E-8 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 SUPERFAMILY SSF50692 542 665 1.91E-34 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 Gene3D G3DSA:3.40.50.740 65 476 3.4E-129 T 14-10-2018 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 Gene3D G3DSA:3.40.228.10 131 358 3.4E-129 T 14-10-2018 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 Gene3D G3DSA:2.40.40.20 530 670 9.0E-27 T 14-10-2018 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 Pfam PF00384 Molybdopterin oxidoreductase 54 471 9.6E-62 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_2133 c8b26d05cf29e8779d320bce60a22ce9 675 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 2 51 2.0E-8 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 5 91 1.7E-30 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 PRINTS PR01703 Manganese superoxide dismutase signature 8 19 8.3E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 PRINTS PR01703 Manganese superoxide dismutase signature 75 88 8.3E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 PRINTS PR01703 Manganese superoxide dismutase signature 165 177 8.3E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 PRINTS PR01703 Manganese superoxide dismutase signature 29 42 8.3E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 PRINTS PR01703 Manganese superoxide dismutase signature 128 136 8.3E-26 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 PIRSF PIRSF000349 1 203 1.8E-79 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 99 198 1.1E-40 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 SUPERFAMILY SSF46609 3 93 1.57E-34 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 SUPERFAMILY SSF54719 95 202 6.55E-45 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 Gene3D G3DSA:2.40.500.20 93 203 2.1E-49 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 167 174 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_0783 1a8b817fae442f27c0567ea9b695d511 203 Gene3D G3DSA:1.10.287.990 22 92 2.4E-32 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Theos_1521 1b45d2380ce389dbc5291bfc644bf537 85 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 41 3.2E-9 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Theos_1521 1b45d2380ce389dbc5291bfc644bf537 85 SUPERFAMILY SSF89447 3 42 1.05E-8 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Theos_1521 1b45d2380ce389dbc5291bfc644bf537 85 Gene3D G3DSA:2.10.260.10 4 43 1.5E-6 T 14-10-2018 Theos_0759 d61b14a28ff6a14aee6d8de0d2ff56f5 168 Gene3D G3DSA:3.90.1140.10 2 163 2.7E-23 T 14-10-2018 Theos_0759 d61b14a28ff6a14aee6d8de0d2ff56f5 168 SUPERFAMILY SSF55144 2 162 1.39E-24 T 14-10-2018 IPR009097 Cyclic phosphodiesterase Theos_0759 d61b14a28ff6a14aee6d8de0d2ff56f5 168 Pfam PF13563 2'-5' RNA ligase superfamily 8 152 1.3E-19 T 14-10-2018 Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 Pfam PF01345 Domain of unknown function DUF11 1017 1128 6.8E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 Pfam PF01345 Domain of unknown function DUF11 360 487 3.6E-14 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 Pfam PF01345 Domain of unknown function DUF11 520 619 3.3E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 Gene3D G3DSA:2.60.40.740 353 512 1.0E-8 T 14-10-2018 Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 526 572 2.4E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1032 1065 4.8E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 373 414 7.2E-15 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 Gene3D G3DSA:2.60.40.10 757 864 4.5E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 Gene3D G3DSA:2.60.40.10 646 755 1.1E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 SUPERFAMILY SSF49464 778 827 2.75E-6 T 14-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 SUPERFAMILY SSF49401 373 495 1.29E-5 T 14-10-2018 IPR008966 Adhesion domain superfamily Theos_0846 358c0f4237df4eaf7bd10850c7642e19 1129 SUPERFAMILY SSF117074 638 719 2.09E-5 T 14-10-2018 Theos_1030 ba12c519742401f73d56cc93eb7a8e2c 278 SUPERFAMILY SSF54285 241 276 4.36E-7 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Theos_1030 ba12c519742401f73d56cc93eb7a8e2c 278 Pfam PF11563 Protoglobin 19 143 1.3E-8 T 14-10-2018 Theos_1030 ba12c519742401f73d56cc93eb7a8e2c 278 Gene3D G3DSA:1.10.490.10 19 170 9.6E-10 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Theos_1030 ba12c519742401f73d56cc93eb7a8e2c 278 Gene3D G3DSA:3.10.20.30 196 277 7.1E-12 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Theos_1030 ba12c519742401f73d56cc93eb7a8e2c 278 Pfam PF02597 ThiS family 234 276 6.1E-6 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Theos_1030 ba12c519742401f73d56cc93eb7a8e2c 278 SUPERFAMILY SSF46458 16 144 4.89E-5 T 14-10-2018 IPR009050 Globin-like superfamily Theos_1613 76515bb3fa4b15c4a5661f5502d650db 222 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 8 200 1.8E-44 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 477 45.289 T 14-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 Gene3D G3DSA:3.40.50.800 283 398 1.8E-31 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 102 270 2.7E-19 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 Gene3D G3DSA:3.30.110.30 404 477 4.7E-23 T 14-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 SUPERFAMILY SSF52954 278 402 2.62E-34 T 14-10-2018 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 Gene3D G3DSA:3.30.930.10 1 282 1.4E-106 T 14-10-2018 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 SUPERFAMILY SSF64586 405 477 2.35E-23 T 14-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 SMART SM00946 410 477 3.5E-28 T 14-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 Pfam PF03129 Anticodon binding domain 289 381 3.2E-17 T 14-10-2018 IPR004154 Anticodon-binding Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 477 2.1E-175 T 14-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 SUPERFAMILY SSF55681 13 276 1.05E-78 T 14-10-2018 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 410 477 2.5E-18 T 14-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 4.3E-8 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 4.3E-8 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 4.3E-8 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Theos_1753 2c6ea0d71478b143d4f1b24de88cab53 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 4.3E-8 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Theos_0056 2e3d5cfb12ee7ddbcac9185924252590 352 Pfam PF00924 Mechanosensitive ion channel 135 333 5.5E-45 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Theos_0056 2e3d5cfb12ee7ddbcac9185924252590 352 SUPERFAMILY SSF82861 89 174 3.4E-11 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Theos_0056 2e3d5cfb12ee7ddbcac9185924252590 352 SUPERFAMILY SSF50182 175 237 2.39E-14 T 14-10-2018 IPR010920 LSM domain superfamily Theos_0056 2e3d5cfb12ee7ddbcac9185924252590 352 SUPERFAMILY SSF82689 240 343 1.57E-24 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 Theos_0056 2e3d5cfb12ee7ddbcac9185924252590 352 Gene3D G3DSA:2.30.30.60 191 240 3.1E-17 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily Theos_0056 2e3d5cfb12ee7ddbcac9185924252590 352 Gene3D G3DSA:3.30.70.100 242 331 1.7E-31 T 14-10-2018 Theos_1173 b33424878761973a587a47d0eac70f8b 340 Pfam PF02515 CoA-transferase family III 10 161 6.0E-30 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 Theos_1173 b33424878761973a587a47d0eac70f8b 340 Pfam PF02515 CoA-transferase family III 196 279 1.3E-5 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 Theos_1173 b33424878761973a587a47d0eac70f8b 340 Gene3D G3DSA:3.40.50.10540 9 191 3.4E-39 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Theos_1173 b33424878761973a587a47d0eac70f8b 340 SUPERFAMILY SSF89796 10 305 6.15E-57 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Theos_1173 b33424878761973a587a47d0eac70f8b 340 Gene3D G3DSA:3.30.1540.10 192 274 6.4E-10 T 14-10-2018 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 Gene3D G3DSA:3.40.630.20 1 192 9.3E-63 T 14-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 PIRSF PIRSF015592 1 192 1.6E-47 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 76 96 9.7E-25 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 2 25 9.7E-25 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 155 167 9.7E-25 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 128 144 9.7E-25 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 58 70 9.7E-25 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 SUPERFAMILY SSF53182 2 190 1.44E-48 T 14-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 Pfam PF01470 Pyroglutamyl peptidase 2 190 8.4E-38 T 14-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 Theos_1544 2a4c95df8a540c1828cdec7c45419004 192 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 126 140 - T 14-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 Theos_0975 39f564fe9dc6e14e6812dd7c3aa38e8f 390 SUPERFAMILY SSF53822 20 386 1.13E-77 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_0975 39f564fe9dc6e14e6812dd7c3aa38e8f 390 Pfam PF13458 Periplasmic binding protein 20 381 1.9E-53 T 14-10-2018 IPR028081 Leucine-binding protein domain Theos_0975 39f564fe9dc6e14e6812dd7c3aa38e8f 390 Gene3D G3DSA:3.40.50.2300 145 382 1.1E-109 T 14-10-2018 Theos_0975 39f564fe9dc6e14e6812dd7c3aa38e8f 390 Gene3D G3DSA:3.40.50.2300 23 368 1.1E-109 T 14-10-2018 Theos_0975 39f564fe9dc6e14e6812dd7c3aa38e8f 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 62 80 7.6E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_0975 39f564fe9dc6e14e6812dd7c3aa38e8f 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 83 93 7.6E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_0975 39f564fe9dc6e14e6812dd7c3aa38e8f 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 250 268 7.6E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_0975 39f564fe9dc6e14e6812dd7c3aa38e8f 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 21 37 7.6E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_1811 d1dcc40a82928a1a445fb222d73a3838 130 Gene3D G3DSA:3.30.920.80 1 129 2.0E-69 T 14-10-2018 IPR038458 NADH-quinone oxidoreductase, subunit 15 superfamily KEGG: 00190+1.6.5.11 Theos_1811 d1dcc40a82928a1a445fb222d73a3838 130 Pfam PF11497 NADH-quinone oxidoreductase chain 15 5 124 9.7E-59 T 14-10-2018 IPR021093 NADH-quinone oxidoreductase, subunit15 KEGG: 00190+1.6.5.11 Theos_1811 d1dcc40a82928a1a445fb222d73a3838 130 SUPERFAMILY SSF55387 4 128 1.73E-62 T 14-10-2018 Theos_0469 716bb0299f4500054056f979e9bc1a84 299 Gene3D G3DSA:3.90.550.10 2 219 1.2E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_0469 716bb0299f4500054056f979e9bc1a84 299 Pfam PF00535 Glycosyl transferase family 2 6 173 2.0E-29 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Theos_0469 716bb0299f4500054056f979e9bc1a84 299 SUPERFAMILY SSF53448 4 275 8.25E-41 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1603 85171c04f1f72e266539e1d809a18486 184 Pfam PF00355 Rieske [2Fe-2S] domain 92 158 1.3E-7 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Theos_1603 85171c04f1f72e266539e1d809a18486 184 SUPERFAMILY SSF50022 38 175 5.53E-19 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Theos_1603 85171c04f1f72e266539e1d809a18486 184 Gene3D G3DSA:2.102.10.10 43 178 1.2E-23 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Theos_0978 ca95089a6479dec4e61e236aecf5d3ce 240 Gene3D G3DSA:3.40.50.300 1 235 2.0E-59 T 14-10-2018 Theos_0978 ca95089a6479dec4e61e236aecf5d3ce 240 Pfam PF00005 ABC transporter 18 162 1.6E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0978 ca95089a6479dec4e61e236aecf5d3ce 240 SUPERFAMILY SSF52540 2 233 8.7E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0978 ca95089a6479dec4e61e236aecf5d3ce 240 SMART SM00382 26 211 4.7E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0978 ca95089a6479dec4e61e236aecf5d3ce 240 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2054 5d4b812765717fb9ee47439ee1679912 378 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 283 1.4E-20 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Theos_2054 5d4b812765717fb9ee47439ee1679912 378 Gene3D G3DSA:3.50.50.100 1 377 9.7E-89 T 14-10-2018 Theos_2054 5d4b812765717fb9ee47439ee1679912 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 2.0E-7 T 14-10-2018 Theos_2054 5d4b812765717fb9ee47439ee1679912 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 2.0E-7 T 14-10-2018 Theos_2054 5d4b812765717fb9ee47439ee1679912 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.0E-7 T 14-10-2018 Theos_2054 5d4b812765717fb9ee47439ee1679912 378 SUPERFAMILY SSF51905 115 241 5.31E-22 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2054 5d4b812765717fb9ee47439ee1679912 378 SUPERFAMILY SSF51905 4 311 3.8E-28 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0434 18953721cb7437c0c071e2614f214b99 383 TIGRFAM TIGR00033 aroC: chorismate synthase 1 363 8.0E-114 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Theos_0434 18953721cb7437c0c071e2614f214b99 383 Pfam PF01264 Chorismate synthase 1 358 5.7E-110 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Theos_0434 18953721cb7437c0c071e2614f214b99 383 PIRSF PIRSF001456 1 381 9.1E-116 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Theos_0434 18953721cb7437c0c071e2614f214b99 383 ProSitePatterns PS00788 Chorismate synthase signature 2. 127 143 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Theos_0434 18953721cb7437c0c071e2614f214b99 383 SUPERFAMILY SSF103263 1 382 8.37E-135 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Theos_0434 18953721cb7437c0c071e2614f214b99 383 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Theos_0434 18953721cb7437c0c071e2614f214b99 383 Hamap MF_00300 Chorismate synthase [aroC]. 1 365 34.106 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Theos_0434 18953721cb7437c0c071e2614f214b99 383 Gene3D G3DSA:3.60.150.10 1 383 1.2E-141 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 PRINTS PR01272 Acetoin utilisation ACUC protein signature 11 31 1.3E-17 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 PRINTS PR01272 Acetoin utilisation ACUC protein signature 339 358 1.3E-17 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 PRINTS PR01272 Acetoin utilisation ACUC protein signature 78 92 1.3E-17 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 PRINTS PR01272 Acetoin utilisation ACUC protein signature 99 112 1.3E-17 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 PRINTS PR01270 Histone deacetylase superfamily signature 121 144 4.4E-19 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 PRINTS PR01270 Histone deacetylase superfamily signature 153 168 4.4E-19 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 PRINTS PR01270 Histone deacetylase superfamily signature 239 249 4.4E-19 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 Gene3D G3DSA:3.40.800.20 1 332 2.7E-98 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 Pfam PF00850 Histone deacetylase domain 17 305 2.7E-72 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_1830 16ea07c3434ac9d1247e6bbed5a3c3ea 375 SUPERFAMILY SSF52768 2 330 5.28E-98 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 268 317 1.4E-11 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 Pfam PF13193 AMP-binding enzyme C-terminal domain 732 811 3.1E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 Pfam PF01614 Bacterial transcriptional regulator 124 224 5.1E-16 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 SUPERFAMILY SSF56801 265 823 1.01E-142 T 14-10-2018 Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 Gene3D G3DSA:3.40.50.12780 309 719 2.3E-95 T 14-10-2018 Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 Pfam PF00501 AMP-binding enzyme 326 723 2.2E-78 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 SUPERFAMILY SSF55781 79 225 5.4E-21 T 14-10-2018 Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 ProSitePatterns PS00455 Putative AMP-binding domain signature. 479 490 - T 14-10-2018 IPR020845 AMP-binding, conserved site Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 Gene3D G3DSA:1.10.10.10 5 69 4.5E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 Pfam PF09339 IclR helix-turn-helix domain 13 57 2.8E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 Gene3D G3DSA:3.30.300.30 720 822 5.7E-23 T 14-10-2018 Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 Gene3D G3DSA:3.30.450.40 76 239 1.0E-26 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1269 1e5e028b6748c0c350a97e8459aa9922 842 SUPERFAMILY SSF46785 8 67 1.19E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1017 c6b816cdc20a810684357ded7f3bbe06 356 Gene3D G3DSA:1.10.443.10 155 354 1.9E-40 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Theos_1017 c6b816cdc20a810684357ded7f3bbe06 356 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 46 133 1.3E-6 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Theos_1017 c6b816cdc20a810684357ded7f3bbe06 356 Pfam PF00589 Phage integrase family 179 340 8.7E-30 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Theos_1017 c6b816cdc20a810684357ded7f3bbe06 356 Gene3D G3DSA:1.10.150.130 34 153 4.9E-10 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Theos_1017 c6b816cdc20a810684357ded7f3bbe06 356 SUPERFAMILY SSF56349 45 348 1.0E-46 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Theos_0320 347a68cd901b11ccf62e36408ba1cc79 572 SUPERFAMILY SSF51445 100 506 8.7E-86 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily Theos_0320 347a68cd901b11ccf62e36408ba1cc79 572 Pfam PF00128 Alpha amylase, catalytic domain 157 254 3.2E-30 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Theos_0320 347a68cd901b11ccf62e36408ba1cc79 572 Pfam PF00128 Alpha amylase, catalytic domain 261 460 2.9E-22 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Theos_0320 347a68cd901b11ccf62e36408ba1cc79 572 SMART SM00642 110 498 2.0E-72 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Theos_0320 347a68cd901b11ccf62e36408ba1cc79 572 Gene3D G3DSA:3.20.20.80 99 500 1.5E-109 T 14-10-2018 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 SUPERFAMILY SSF55681 144 481 3.58E-113 T 14-10-2018 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 Pfam PF01336 OB-fold nucleic acid binding domain 53 128 3.7E-17 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 2 484 7.5E-178 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 7 484 41.713 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 Pfam PF00152 tRNA synthetases class II (D, K and N) 145 480 3.4E-82 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 SUPERFAMILY SSF50249 1 137 1.56E-35 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 181 191 9.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 226 239 9.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 261 9.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 197 213 9.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 365 381 9.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 Gene3D G3DSA:3.30.930.10 140 491 1.5E-129 T 14-10-2018 Theos_1156 7158244e2562a2ceb4f971d85a46e964 491 Gene3D G3DSA:2.40.50.140 1 139 6.1E-38 T 14-10-2018 Theos_1457 91d44cee03db6c9f9a5fcdc6e78fece9 237 SUPERFAMILY SSF158997 6 50 1.09E-5 T 14-10-2018 Theos_1457 91d44cee03db6c9f9a5fcdc6e78fece9 237 Gene3D G3DSA:3.40.50.150 10 200 2.3E-23 T 14-10-2018 Theos_1457 91d44cee03db6c9f9a5fcdc6e78fece9 237 Pfam PF08241 Methyltransferase domain 103 189 7.1E-13 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Theos_1457 91d44cee03db6c9f9a5fcdc6e78fece9 237 SUPERFAMILY SSF53335 63 228 6.21E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1094 79c616b6c654af264ae9914a8929ffac 273 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 12 230 1.3E-25 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 Theos_1094 79c616b6c654af264ae9914a8929ffac 273 SUPERFAMILY SSF51735 4 270 1.6E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1094 79c616b6c654af264ae9914a8929ffac 273 Gene3D G3DSA:3.40.50.720 100 257 1.2E-48 T 14-10-2018 Theos_1094 79c616b6c654af264ae9914a8929ffac 273 Gene3D G3DSA:3.30.1780.10 17 267 1.2E-48 T 14-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 Theos_2429 a6256b7ceac193bbc6aba63419f9e20b 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 334 6.8E-40 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2429 a6256b7ceac193bbc6aba63419f9e20b 335 SUPERFAMILY SSF161098 91 318 1.7E-14 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 Pfam PF11897 Protein of unknown function (DUF3417) 13 113 3.0E-29 T 14-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 584 596 - T 14-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 Pfam PF00343 Carbohydrate phosphorylase 117 165 1.9E-4 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 Pfam PF00343 Carbohydrate phosphorylase 263 624 5.4E-15 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 Gene3D G3DSA:3.40.50.2000 255 406 1.1E-10 T 14-10-2018 Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 SUPERFAMILY SSF53756 5 691 2.86E-186 T 14-10-2018 Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 101 690 5.7E-226 T 14-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 Gene3D G3DSA:3.40.50.2000 415 654 1.2E-36 T 14-10-2018 Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 Gene3D G3DSA:3.40.50.2000 109 209 3.8E-10 T 14-10-2018 Theos_1189 0c79c94332443af7b5750d0fd7c7a92d 815 PIRSF PIRSF000460 1 716 2.8E-251 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Theos_1659 d5b661f2017853767e450381d0848d37 577 Pfam PF00890 FAD binding domain 7 397 4.5E-114 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1659 d5b661f2017853767e450381d0848d37 577 PIRSF PIRSF000171 1 570 1.2E-48 T 14-10-2018 Theos_1659 d5b661f2017853767e450381d0848d37 577 SUPERFAMILY SSF56425 232 350 5.23E-42 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1659 d5b661f2017853767e450381d0848d37 577 SUPERFAMILY SSF51905 3 420 6.24E-76 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1659 d5b661f2017853767e450381d0848d37 577 Gene3D G3DSA:3.50.50.60 7 408 8.2E-162 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1659 d5b661f2017853767e450381d0848d37 577 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 577 4.4E-243 T 14-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1659 d5b661f2017853767e450381d0848d37 577 Gene3D G3DSA:3.90.700.10 242 345 8.2E-162 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1659 d5b661f2017853767e450381d0848d37 577 Gene3D G3DSA:1.20.58.100 422 538 8.6E-37 T 14-10-2018 Theos_1659 d5b661f2017853767e450381d0848d37 577 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 3 577 1.1E-283 T 14-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1659 d5b661f2017853767e450381d0848d37 577 Pfam PF02910 Fumarate reductase flavoprotein C-term 451 577 2.5E-42 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1659 d5b661f2017853767e450381d0848d37 577 Gene3D G3DSA:4.10.80.40 539 573 1.3E-7 T 14-10-2018 Theos_1659 d5b661f2017853767e450381d0848d37 577 SUPERFAMILY SSF46977 443 577 1.83E-51 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1659 d5b661f2017853767e450381d0848d37 577 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.1E-6 T 14-10-2018 Theos_1659 d5b661f2017853767e450381d0848d37 577 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 3.1E-6 T 14-10-2018 Theos_1659 d5b661f2017853767e450381d0848d37 577 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 14-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1659 d5b661f2017853767e450381d0848d37 577 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-7 T 14-10-2018 Theos_1659 d5b661f2017853767e450381d0848d37 577 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 1.3E-7 T 14-10-2018 Theos_0207 c676352c74a91ec542b9446ade2f329d 169 SUPERFAMILY SSF109854 7 167 6.56E-25 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes Theos_0207 c676352c74a91ec542b9446ade2f329d 169 Pfam PF12867 DinB superfamily 17 163 4.7E-19 T 14-10-2018 IPR024775 DinB-like domain Theos_0747 cfd6bde1ef0484a0647431a29b0cf796 476 SUPERFAMILY SSF53383 3 469 1.28E-124 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0747 cfd6bde1ef0484a0647431a29b0cf796 476 Gene3D G3DSA:3.40.640.10 83 317 4.2E-58 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0747 cfd6bde1ef0484a0647431a29b0cf796 476 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 4 472 54.927 T 14-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 Theos_0747 cfd6bde1ef0484a0647431a29b0cf796 476 Pfam PF02347 Glycine cleavage system P-protein 88 380 1.9E-6 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Theos_0747 cfd6bde1ef0484a0647431a29b0cf796 476 Gene3D G3DSA:3.90.1150.10 332 457 4.8E-45 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 SUPERFAMILY SSF55874 157 309 6.02E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1726 e37a9775c4bc66753c86a447d3604556 721 SUPERFAMILY SSF47384 80 155 1.79E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 Pfam PF13432 Tetratricopeptide repeat 561 605 2.5E-4 T 14-10-2018 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 Pfam PF13432 Tetratricopeptide repeat 617 678 1.9E-8 T 14-10-2018 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 SMART SM00388 90 156 3.2E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 Pfam PF00512 His Kinase A (phospho-acceptor) domain 92 156 3.1E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 Gene3D G3DSA:1.25.40.10 523 713 3.7E-34 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 SUPERFAMILY SSF48452 558 710 8.54E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 PRINTS PR00344 Bacterial sensor protein C-terminal signature 256 266 9.3E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 PRINTS PR00344 Bacterial sensor protein C-terminal signature 238 252 9.3E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 308 9.3E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 289 9.3E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 Gene3D G3DSA:1.10.287.130 99 153 3.3E-55 T 14-10-2018 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 SMART SM00028 577 610 0.11 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 SMART SM00028 612 643 31.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 SMART SM00028 644 677 32.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 SMART SM00028 678 711 36.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1726 e37a9775c4bc66753c86a447d3604556 721 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 201 309 2.7E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1726 e37a9775c4bc66753c86a447d3604556 721 Gene3D G3DSA:3.30.565.10 154 308 3.3E-55 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1726 e37a9775c4bc66753c86a447d3604556 721 SMART SM00387 201 311 1.2E-39 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0392 608ab02208e8d44e7faa1635144068c7 630 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 77 345 3.9E-44 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 124 136 2.1E-19 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 335 354 2.1E-19 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 540 553 2.1E-19 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 241 254 2.1E-19 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 100 118 2.1E-19 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PIRSF PIRSF001336 1 630 1.5E-244 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 Gene3D G3DSA:2.40.37.10 16 567 2.6E-217 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 Gene3D G3DSA:3.20.20.10 69 350 2.6E-217 T 14-10-2018 IPR029066 PLP-binding barrel Theos_0392 608ab02208e8d44e7faa1635144068c7 630 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 100 118 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Theos_0392 608ab02208e8d44e7faa1635144068c7 630 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 5 630 39.654 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01180 Arginine decarboxylase signature 148 163 6.2E-64 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01180 Arginine decarboxylase signature 198 220 6.2E-64 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01180 Arginine decarboxylase signature 487 512 6.2E-64 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01180 Arginine decarboxylase signature 540 561 6.2E-64 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01180 Arginine decarboxylase signature 325 342 6.2E-64 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01180 Arginine decarboxylase signature 68 83 6.2E-64 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01180 Arginine decarboxylase signature 92 106 6.2E-64 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01180 Arginine decarboxylase signature 174 195 6.2E-64 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 PRINTS PR01180 Arginine decarboxylase signature 462 483 6.2E-64 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 Gene3D G3DSA:1.20.58.930 368 458 2.6E-217 T 14-10-2018 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 SUPERFAMILY SSF50621 458 566 2.88E-10 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Theos_0392 608ab02208e8d44e7faa1635144068c7 630 SUPERFAMILY SSF51419 68 347 2.24E-64 T 14-10-2018 IPR029066 PLP-binding barrel Theos_0392 608ab02208e8d44e7faa1635144068c7 630 TIGRFAM TIGR01273 speA: arginine decarboxylase 9 629 2.8E-213 T 14-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Theos_1637 9dadabca44a42923d8da340491502d6d 343 Gene3D G3DSA:3.40.50.10490 1 190 6.9E-46 T 14-10-2018 Theos_1637 9dadabca44a42923d8da340491502d6d 343 SUPERFAMILY SSF53697 22 341 5.56E-66 T 14-10-2018 Theos_1637 9dadabca44a42923d8da340491502d6d 343 Pfam PF01380 SIS domain 197 288 4.1E-11 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Theos_1637 9dadabca44a42923d8da340491502d6d 343 Pfam PF01380 SIS domain 42 164 3.4E-14 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Theos_1637 9dadabca44a42923d8da340491502d6d 343 Gene3D G3DSA:3.40.50.10490 191 342 2.1E-39 T 14-10-2018 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 Gene3D G3DSA:1.20.140.10 241 385 5.4E-58 T 14-10-2018 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 Gene3D G3DSA:1.10.540.10 4 122 1.0E-33 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 383 1.3E-50 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 SUPERFAMILY SSF47203 232 384 7.25E-60 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 PIRSF PIRSF016578 5 384 1.1E-31 T 14-10-2018 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 221 1.4E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 Gene3D G3DSA:2.40.110.10 123 240 2.6E-34 T 14-10-2018 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 4.7E-28 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Theos_1921 b8b83b4094f314203ca47bb19ce331f1 386 SUPERFAMILY SSF56645 4 234 4.71E-70 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_2007 4a36738f2794120f5481883b714a40dc 303 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 119 5.0E-25 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Theos_2007 4a36738f2794120f5481883b714a40dc 303 SUPERFAMILY SSF111331 4 288 1.0E-65 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily Theos_2007 4a36738f2794120f5481883b714a40dc 303 SMART SM00046 2 125 7.7E-7 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Theos_2007 4a36738f2794120f5481883b714a40dc 303 Gene3D G3DSA:3.40.50.10330 2 122 2.3E-27 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 Theos_2007 4a36738f2794120f5481883b714a40dc 303 Gene3D G3DSA:2.60.200.40 123 274 3.8E-33 T 14-10-2018 Theos_1155 feeb4d40ed7f190ecf71cd31392a0185 156 Gene3D G3DSA:1.10.287.180 1 77 6.1E-31 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Theos_1155 feeb4d40ed7f190ecf71cd31392a0185 156 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Theos_1155 feeb4d40ed7f190ecf71cd31392a0185 156 SUPERFAMILY SSF54534 80 155 4.97E-17 T 14-10-2018 Theos_1155 feeb4d40ed7f190ecf71cd31392a0185 156 Pfam PF03449 Transcription elongation factor, N-terminal 6 74 3.6E-15 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 Theos_1155 feeb4d40ed7f190ecf71cd31392a0185 156 PIRSF PIRSF006092 1 156 2.0E-45 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 Theos_1155 feeb4d40ed7f190ecf71cd31392a0185 156 SUPERFAMILY SSF46557 4 76 7.85E-13 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Theos_1155 feeb4d40ed7f190ecf71cd31392a0185 156 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 155 8.0E-21 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Theos_1155 feeb4d40ed7f190ecf71cd31392a0185 156 Gene3D G3DSA:3.10.50.30 79 151 2.3E-27 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 188 3.1E-41 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 Pfam PF01330 RuvA N terminal domain 1 60 1.1E-14 T 14-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 SUPERFAMILY SSF46929 143 188 6.15E-10 T 14-10-2018 IPR036267 RuvA, C-terminal domain superfamily Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 Gene3D G3DSA:1.10.150.20 64 135 4.0E-23 T 14-10-2018 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 SUPERFAMILY SSF50249 1 62 3.26E-10 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 189 27.39 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 SMART SM00278 72 91 0.14 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 SMART SM00278 107 126 32.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 SUPERFAMILY SSF47781 67 133 6.07E-19 T 14-10-2018 IPR010994 RuvA domain 2-like Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 Pfam PF07499 RuvA, C-terminal domain 143 188 9.9E-9 T 14-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 Pfam PF14520 Helix-hairpin-helix domain 71 128 1.1E-15 T 14-10-2018 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 Gene3D G3DSA:2.40.50.140 1 63 1.7E-21 T 14-10-2018 Theos_0135 e33da3846ff3a5710f88e69554bd5b35 189 Gene3D G3DSA:1.10.8.10 138 189 3.7E-13 T 14-10-2018 Theos_1527 f0fe6bb96b493433865e37e5f6413ce8 341 PIRSF PIRSF005261 1 300 1.3E-65 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 Theos_1527 f0fe6bb96b493433865e37e5f6413ce8 341 Gene3D G3DSA:3.90.1280.10 239 300 4.8E-16 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 Theos_1527 f0fe6bb96b493433865e37e5f6413ce8 341 SUPERFAMILY SSF118352 240 298 2.75E-18 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 Theos_1527 f0fe6bb96b493433865e37e5f6413ce8 341 Pfam PF01430 Hsp33 protein 3 288 1.4E-78 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 Theos_1527 f0fe6bb96b493433865e37e5f6413ce8 341 SUPERFAMILY SSF64397 4 250 3.53E-61 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 Theos_1527 f0fe6bb96b493433865e37e5f6413ce8 341 Gene3D G3DSA:3.55.30.10 1 230 1.6E-78 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 Theos_1527 f0fe6bb96b493433865e37e5f6413ce8 341 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 299 33.825 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 Theos_2094 9ee9f586dad3f19ea2186b533fe89fe2 289 Gene3D G3DSA:3.40.50.720 2 157 9.5E-55 T 14-10-2018 Theos_2094 9ee9f586dad3f19ea2186b533fe89fe2 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 156 1.6E-39 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 Theos_2094 9ee9f586dad3f19ea2186b533fe89fe2 289 SUPERFAMILY SSF48179 158 287 1.7E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Theos_2094 9ee9f586dad3f19ea2186b533fe89fe2 289 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 Theos_2094 9ee9f586dad3f19ea2186b533fe89fe2 289 PIRSF PIRSF000103 1 288 8.4E-60 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Theos_2094 9ee9f586dad3f19ea2186b533fe89fe2 289 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 159 280 2.6E-41 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 Theos_2094 9ee9f586dad3f19ea2186b533fe89fe2 289 SUPERFAMILY SSF51735 3 157 7.98E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2094 9ee9f586dad3f19ea2186b533fe89fe2 289 Gene3D G3DSA:1.10.1040.10 158 289 4.2E-31 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Theos_1600 b3dda48c83022dec63d7d263b983e03a 99 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 16 96 3.0E-29 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1600 b3dda48c83022dec63d7d263b983e03a 99 SUPERFAMILY SSF46992 10 92 5.62E-25 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1600 b3dda48c83022dec63d7d263b983e03a 99 Gene3D G3DSA:1.20.58.110 1 99 8.7E-31 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1600 b3dda48c83022dec63d7d263b983e03a 99 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 90 16.159 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1600 b3dda48c83022dec63d7d263b983e03a 99 TIGRFAM TIGR00029 S20: ribosomal protein bS20 9 91 3.8E-20 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1600 b3dda48c83022dec63d7d263b983e03a 99 Pfam PF01649 Ribosomal protein S20 11 88 5.5E-22 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0471 8394df9b32e4bf8c07d624ff1af7856e 396 Pfam PF04932 O-Antigen ligase 184 336 1.3E-13 T 14-10-2018 IPR007016 O-antigen ligase-related Theos_0435 4792a06c506033112bc08dc548a187a5 754 Pfam PF00263 Bacterial type II and III secretion system protein 591 747 5.9E-38 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 Theos_0435 4792a06c506033112bc08dc548a187a5 754 Gene3D G3DSA:3.30.1370.120 447 533 1.1E-17 T 14-10-2018 IPR038591 NolW-like superfamily Theos_0435 4792a06c506033112bc08dc548a187a5 754 Pfam PF03958 Bacterial type II/III secretion system short domain 390 449 2.0E-6 T 14-10-2018 IPR005644 NolW-like Theos_0435 4792a06c506033112bc08dc548a187a5 754 Pfam PF03958 Bacterial type II/III secretion system short domain 456 531 1.5E-17 T 14-10-2018 IPR005644 NolW-like Theos_0435 4792a06c506033112bc08dc548a187a5 754 PRINTS PR00811 Bacterial general secretion pathway protein D signature 712 730 1.8E-6 T 14-10-2018 IPR001775 GspD/PilQ family Theos_0435 4792a06c506033112bc08dc548a187a5 754 PRINTS PR00811 Bacterial general secretion pathway protein D signature 515 525 1.8E-6 T 14-10-2018 IPR001775 GspD/PilQ family Theos_0435 4792a06c506033112bc08dc548a187a5 754 PRINTS PR00811 Bacterial general secretion pathway protein D signature 735 749 1.8E-6 T 14-10-2018 IPR001775 GspD/PilQ family Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 Hamap MF_01201 Alanine racemase. 4 351 27.142 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 Gene3D G3DSA:3.20.20.10 14 221 2.2E-51 T 14-10-2018 IPR029066 PLP-binding barrel Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 Gene3D G3DSA:2.40.37.10 222 361 1.9E-32 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 SMART SM01005 227 351 1.9E-37 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 SUPERFAMILY SSF50621 216 355 4.53E-35 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 TIGRFAM TIGR00492 alr: alanine racemase 7 351 4.6E-63 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 SUPERFAMILY SSF51419 11 228 2.62E-51 T 14-10-2018 IPR029066 PLP-binding barrel Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 Pfam PF00842 Alanine racemase, C-terminal domain 227 350 5.0E-29 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 Pfam PF01168 Alanine racemase, N-terminal domain 11 220 2.6E-52 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 PRINTS PR00992 Alanine racemase signature 280 297 2.5E-41 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 PRINTS PR00992 Alanine racemase signature 243 258 2.5E-41 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 PRINTS PR00992 Alanine racemase signature 28 44 2.5E-41 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 PRINTS PR00992 Alanine racemase signature 158 169 2.5E-41 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 PRINTS PR00992 Alanine racemase signature 64 82 2.5E-41 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 PRINTS PR00992 Alanine racemase signature 260 275 2.5E-41 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 PRINTS PR00992 Alanine racemase signature 333 346 2.5E-41 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_2020 b25b8aefaa325978611187cadd0e1bae 361 PRINTS PR00992 Alanine racemase signature 125 137 2.5E-41 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_0075 feab6c8f9c580b12a6c34c90b5b37cc0 452 Pfam PF01235 Sodium:alanine symporter family 65 442 1.5E-97 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Theos_0075 feab6c8f9c580b12a6c34c90b5b37cc0 452 PRINTS PR00175 Sodium/alanine symporter signature 351 373 7.9E-34 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Theos_0075 feab6c8f9c580b12a6c34c90b5b37cc0 452 PRINTS PR00175 Sodium/alanine symporter signature 410 430 7.9E-34 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Theos_0075 feab6c8f9c580b12a6c34c90b5b37cc0 452 PRINTS PR00175 Sodium/alanine symporter signature 96 118 7.9E-34 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Theos_0075 feab6c8f9c580b12a6c34c90b5b37cc0 452 PRINTS PR00175 Sodium/alanine symporter signature 215 234 7.9E-34 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Theos_0075 feab6c8f9c580b12a6c34c90b5b37cc0 452 PRINTS PR00175 Sodium/alanine symporter signature 187 205 7.9E-34 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Theos_0075 feab6c8f9c580b12a6c34c90b5b37cc0 452 PRINTS PR00175 Sodium/alanine symporter signature 309 327 7.9E-34 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Theos_0075 feab6c8f9c580b12a6c34c90b5b37cc0 452 TIGRFAM TIGR00835 agcS: amino acid carrier protein 22 438 2.6E-99 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Theos_0351 662761de91958bc0f8fe95aa53dafae1 216 Pfam PF00072 Response regulator receiver domain 3 109 1.9E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0351 662761de91958bc0f8fe95aa53dafae1 216 SMART SM00862 141 211 8.8E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0351 662761de91958bc0f8fe95aa53dafae1 216 SUPERFAMILY SSF52172 1 160 3.42E-34 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0351 662761de91958bc0f8fe95aa53dafae1 216 SMART SM00448 1 109 3.5E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0351 662761de91958bc0f8fe95aa53dafae1 216 Gene3D G3DSA:3.40.50.2300 1 118 2.4E-31 T 14-10-2018 Theos_0351 662761de91958bc0f8fe95aa53dafae1 216 Gene3D G3DSA:1.10.10.10 119 215 9.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0351 662761de91958bc0f8fe95aa53dafae1 216 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 211 8.7E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 SMART SM00959 16 57 1.6E-10 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 SUPERFAMILY SSF50249 62 134 9.42E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 Gene3D G3DSA:2.40.50.140 10 138 2.7E-30 T 14-10-2018 Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 Gene3D G3DSA:3.40.50.300 139 426 1.8E-125 T 14-10-2018 Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 SUPERFAMILY SSF52540 100 378 2.35E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 TIGRFAM TIGR00767 rho: transcription termination factor Rho 14 423 6.7E-177 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 SMART SM00382 176 362 2.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 165 370 1.7E-22 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 Pfam PF07498 Rho termination factor, N-terminal domain 16 57 3.0E-11 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 Pfam PF07497 Rho termination factor, RNA-binding domain 62 134 7.3E-20 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 SUPERFAMILY SSF68912 13 57 7.06E-8 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily Theos_1464 9f505d92466e35ee3c0df98d25d51939 426 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 426 191.001 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Theos_1358 90d36e14a34d761810ddda50b528070e 373 Gene3D G3DSA:3.40.190.10 21 306 4.5E-31 T 14-10-2018 Theos_1358 90d36e14a34d761810ddda50b528070e 373 SUPERFAMILY SSF53850 14 308 4.76E-35 T 14-10-2018 Theos_1358 90d36e14a34d761810ddda50b528070e 373 Gene3D G3DSA:3.40.190.10 99 240 4.5E-31 T 14-10-2018 Theos_1358 90d36e14a34d761810ddda50b528070e 373 Pfam PF16868 NMT1-like family 29 306 1.9E-15 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Theos_0879 9c7b5ebf3931aed18b9df2eeb101025b 224 Pfam PF11967 Recombination protein O N terminal 9 79 3.1E-6 T 14-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal Theos_0879 9c7b5ebf3931aed18b9df2eeb101025b 224 SUPERFAMILY SSF50249 7 79 6.17E-7 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0879 9c7b5ebf3931aed18b9df2eeb101025b 224 Gene3D G3DSA:2.40.50.140 3 86 2.2E-21 T 14-10-2018 Theos_2322 05b7f37cd210c5b43058cc5102b7453d 360 Gene3D G3DSA:3.30.420.180 224 352 2.2E-39 T 14-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 Theos_2322 05b7f37cd210c5b43058cc5102b7453d 360 Pfam PF11761 Cobalamin biosynthesis central region 146 230 1.5E-8 T 14-10-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 Theos_2322 05b7f37cd210c5b43058cc5102b7453d 360 SUPERFAMILY SSF159664 226 351 7.98E-36 T 14-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 Theos_2322 05b7f37cd210c5b43058cc5102b7453d 360 SUPERFAMILY SSF159672 10 240 5.75E-55 T 14-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 Theos_2322 05b7f37cd210c5b43058cc5102b7453d 360 Pfam PF11760 Cobalamin synthesis G N-terminal 61 141 4.8E-31 T 14-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 Theos_2322 05b7f37cd210c5b43058cc5102b7453d 360 Gene3D G3DSA:3.40.50.11220 11 136 1.1E-26 T 14-10-2018 Theos_2322 05b7f37cd210c5b43058cc5102b7453d 360 Pfam PF01890 Cobalamin synthesis G C-terminus 233 347 9.5E-32 T 14-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 Pfam PF00453 Ribosomal protein L20 3 109 5.3E-48 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 7.8E-40 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 7.8E-40 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 7.8E-40 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 SUPERFAMILY SSF74731 2 116 1.44E-47 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.645 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 Gene3D G3DSA:1.10.720.90 2 55 2.6E-23 T 14-10-2018 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 2.0E-16 T 14-10-2018 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 Gene3D G3DSA:1.10.1900.20 56 118 2.2E-32 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.6E-50 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0779 b508eced2eb8151f9f47b5d7faf1c995 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2234 961e67b910e8841605c213f153ebc002 554 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 279 1.4E-26 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_2234 961e67b910e8841605c213f153ebc002 554 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 529 550 8.2E-8 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Theos_2234 961e67b910e8841605c213f153ebc002 554 SUPERFAMILY SSF52540 319 549 7.27E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2234 961e67b910e8841605c213f153ebc002 554 SMART SM00382 345 527 1.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2234 961e67b910e8841605c213f153ebc002 554 Gene3D G3DSA:3.40.50.300 318 551 4.9E-57 T 14-10-2018 Theos_2234 961e67b910e8841605c213f153ebc002 554 Pfam PF00005 ABC transporter 338 479 9.1E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 ProSitePatterns PS01166 RNA polymerases beta chain signature. 836 848 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 SUPERFAMILY SSF64484 4 1113 0.0 T 14-10-2018 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Pfam PF04563 RNA polymerase beta subunit 18 379 8.0E-39 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Pfam PF10385 RNA polymerase beta subunit external 1 domain 471 535 4.0E-24 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Pfam PF04560 RNA polymerase Rpb2, domain 7 1028 1102 5.3E-26 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Gene3D G3DSA:2.40.50.100 597 671 0.0 T 14-10-2018 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Pfam PF04561 RNA polymerase Rpb2, domain 2 142 334 9.8E-11 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Gene3D G3DSA:3.90.1100.10 9 596 0.0 T 14-10-2018 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Pfam PF00562 RNA polymerase Rpb2, domain 6 597 1026 7.7E-150 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Gene3D G3DSA:2.40.270.10 7 1004 0.0 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Gene3D G3DSA:2.40.50.150 707 834 0.0 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Gene3D G3DSA:3.90.1110.10 147 328 0.0 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Pfam PF04565 RNA polymerase Rpb2, domain 3 393 461 4.1E-29 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 231 808 8.6E-254 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Gene3D G3DSA:3.90.1800.10 1014 1067 1.6E-10 T 14-10-2018 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 4 1104 11.801 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0185 4e79205511f0bf19be5960dfb818cc68 1119 Gene3D G3DSA:2.30.150.10 474 539 0.0 T 14-10-2018 Theos_0337 05afa26f9985c7415ce83480ef761a0a 129 Gene3D G3DSA:3.40.1530.10 1 129 3.2E-52 T 14-10-2018 IPR036828 TTHA1528-like superfamily Theos_0337 05afa26f9985c7415ce83480ef761a0a 129 SUPERFAMILY SSF143592 1 125 2.48E-46 T 14-10-2018 IPR036828 TTHA1528-like superfamily Theos_0337 05afa26f9985c7415ce83480ef761a0a 129 Pfam PF11432 Protein of unknown function (DUF3197) 15 125 5.7E-39 T 14-10-2018 IPR024443 Domain of unknown function DUF3197 Theos_1513 34d7d11e98e4274b53aa4cd787dcc80a 521 Gene3D G3DSA:3.90.226.10 265 521 6.1E-94 T 14-10-2018 Theos_1513 34d7d11e98e4274b53aa4cd787dcc80a 521 SUPERFAMILY SSF52096 230 521 3.32E-90 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_1513 34d7d11e98e4274b53aa4cd787dcc80a 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 100 114 3.4E-6 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_1513 34d7d11e98e4274b53aa4cd787dcc80a 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 170 187 3.4E-6 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_1513 34d7d11e98e4274b53aa4cd787dcc80a 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 199 210 3.4E-6 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_1513 34d7d11e98e4274b53aa4cd787dcc80a 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 152 3.4E-6 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_1513 34d7d11e98e4274b53aa4cd787dcc80a 521 Gene3D G3DSA:3.90.226.10 8 263 3.2E-95 T 14-10-2018 Theos_1513 34d7d11e98e4274b53aa4cd787dcc80a 521 SUPERFAMILY SSF52096 12 261 2.41E-79 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_1513 34d7d11e98e4274b53aa4cd787dcc80a 521 Pfam PF01039 Carboxyl transferase domain 34 519 2.3E-189 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 2.3E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 2.3E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.3E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 Gene3D G3DSA:3.40.50.720 2 243 8.7E-72 T 14-10-2018 Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 2.7E-59 T 14-10-2018 Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 1.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.8E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 169 0.0052 T 14-10-2018 Theos_2458 01bebe711675887bfc0bd2e3b5c5ed46 243 SUPERFAMILY SSF51735 2 242 3.72E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1374 c23c370d288b11406df823173c98fe5f 347 PIRSF PIRSF000530 1 345 1.1E-103 T 14-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Theos_1374 c23c370d288b11406df823173c98fe5f 347 PRINTS PR00473 Galactokinase signature 98 116 1.1E-21 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Theos_1374 c23c370d288b11406df823173c98fe5f 347 PRINTS PR00473 Galactokinase signature 246 260 1.1E-21 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Theos_1374 c23c370d288b11406df823173c98fe5f 347 PRINTS PR00473 Galactokinase signature 19 37 1.1E-21 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Theos_1374 c23c370d288b11406df823173c98fe5f 347 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 107 118 - T 14-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 Theos_1374 c23c370d288b11406df823173c98fe5f 347 SUPERFAMILY SSF54211 3 189 9.11E-52 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_1374 c23c370d288b11406df823173c98fe5f 347 Pfam PF08544 GHMP kinases C terminal 263 326 9.3E-16 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain Theos_1374 c23c370d288b11406df823173c98fe5f 347 Gene3D G3DSA:3.30.70.890 188 337 2.3E-105 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Theos_1374 c23c370d288b11406df823173c98fe5f 347 SUPERFAMILY SSF55060 191 341 2.16E-42 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Theos_1374 c23c370d288b11406df823173c98fe5f 347 Pfam PF10509 Galactokinase galactose-binding signature 3 49 2.9E-16 T 14-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Theos_1374 c23c370d288b11406df823173c98fe5f 347 Pfam PF00288 GHMP kinases N terminal domain 101 167 2.7E-16 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Theos_1374 c23c370d288b11406df823173c98fe5f 347 Gene3D G3DSA:3.30.230.10 15 187 2.3E-105 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_1374 c23c370d288b11406df823173c98fe5f 347 PRINTS PR00959 Mevalonate kinase family signature 17 41 7.7E-40 T 14-10-2018 Theos_1374 c23c370d288b11406df823173c98fe5f 347 PRINTS PR00959 Mevalonate kinase family signature 105 127 7.7E-40 T 14-10-2018 Theos_1374 c23c370d288b11406df823173c98fe5f 347 PRINTS PR00959 Mevalonate kinase family signature 309 326 7.7E-40 T 14-10-2018 Theos_1374 c23c370d288b11406df823173c98fe5f 347 PRINTS PR00959 Mevalonate kinase family signature 148 167 7.7E-40 T 14-10-2018 Theos_1374 c23c370d288b11406df823173c98fe5f 347 TIGRFAM TIGR00131 gal_kin: galactokinase 3 342 1.7E-77 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Theos_1705 40dacc8234214adcfcee932d8e9629bc 570 Pfam PF08439 Oligopeptidase F 103 168 2.3E-17 T 14-10-2018 IPR013647 Oligopeptidase F, N-terminal domain Theos_1705 40dacc8234214adcfcee932d8e9629bc 570 Gene3D G3DSA:1.20.140.70 16 160 4.1E-14 T 14-10-2018 Theos_1705 40dacc8234214adcfcee932d8e9629bc 570 Gene3D G3DSA:1.10.1370.20 208 570 2.2E-104 T 14-10-2018 Theos_1705 40dacc8234214adcfcee932d8e9629bc 570 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 2 569 5.5E-192 T 14-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 Theos_1705 40dacc8234214adcfcee932d8e9629bc 570 SUPERFAMILY SSF55486 42 568 5.98E-92 T 14-10-2018 Theos_1705 40dacc8234214adcfcee932d8e9629bc 570 Pfam PF01432 Peptidase family M3 318 555 2.6E-31 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 Theos_2173 0d2e5cd49e278da1dda2f8bb8c57c67e 373 Pfam PF12698 ABC-2 family transporter protein 25 364 2.2E-44 T 14-10-2018 Theos_2173 0d2e5cd49e278da1dda2f8bb8c57c67e 373 PRINTS PR00164 ABC-2 type transport system membrane protein signature 257 281 2.1E-6 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Theos_2173 0d2e5cd49e278da1dda2f8bb8c57c67e 373 PRINTS PR00164 ABC-2 type transport system membrane protein signature 314 333 2.1E-6 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Theos_2173 0d2e5cd49e278da1dda2f8bb8c57c67e 373 PRINTS PR00164 ABC-2 type transport system membrane protein signature 294 313 2.1E-6 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Theos_1964 c0575094811763ff1afe2a074e936c15 109 Gene3D G3DSA:3.30.70.120 3 109 1.0E-46 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Theos_1964 c0575094811763ff1afe2a074e936c15 109 Pfam PF02641 Uncharacterized ACR, COG1993 8 104 1.7E-44 T 14-10-2018 IPR003793 Domain of unknown function DUF190 Theos_1964 c0575094811763ff1afe2a074e936c15 109 SUPERFAMILY SSF54913 6 105 2.67E-39 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 SUPERFAMILY SSF50156 239 329 5.13E-17 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 SUPERFAMILY SSF50494 39 211 6.85E-32 T 14-10-2018 IPR009003 Peptidase S1, PA clan Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 Pfam PF13365 Trypsin-like peptidase domain 62 194 1.4E-17 T 14-10-2018 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 Gene3D G3DSA:2.40.10.120 30 213 5.3E-26 T 14-10-2018 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 SMART SM00228 231 319 6.3E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 Pfam PF13180 PDZ domain 254 328 7.8E-12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 Gene3D G3DSA:2.30.42.10 230 330 8.0E-23 T 14-10-2018 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 PRINTS PR00834 HtrA/DegQ protease family signature 91 111 5.5E-9 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 PRINTS PR00834 HtrA/DegQ protease family signature 187 204 5.5E-9 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 PRINTS PR00834 HtrA/DegQ protease family signature 277 289 5.5E-9 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 PRINTS PR00834 HtrA/DegQ protease family signature 165 182 5.5E-9 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1063 05b79e31388c76f9b4b08afa45d84a19 334 PRINTS PR00834 HtrA/DegQ protease family signature 70 82 5.5E-9 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 Gene3D G3DSA:2.40.50.100 59 91 5.8E-9 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 SUPERFAMILY SSF111369 141 276 2.09E-13 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 Gene3D G3DSA:2.40.50.100 213 251 1.3E-26 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 Gene3D G3DSA:2.40.420.20 35 46 5.8E-9 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 Pfam PF13437 HlyD family secretion protein 216 280 3.7E-10 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 Gene3D G3DSA:1.10.287.470 128 212 1.3E-26 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 Gene3D G3DSA:2.40.420.20 320 388 1.3E-26 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 SUPERFAMILY SSF111369 51 141 6.54E-8 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 Gene3D G3DSA:2.40.30.170 47 58 5.8E-9 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 Gene3D G3DSA:2.40.30.170 252 319 1.3E-26 T 14-10-2018 Theos_1420 2e245727b5ba001a32505f1ecc673cb2 392 Gene3D G3DSA:1.10.287.470 92 122 5.8E-9 T 14-10-2018 Theos_2456 216398d308e1d5186e7ea4b399acf028 160 Gene3D G3DSA:1.10.1660.10 11 141 1.9E-17 T 14-10-2018 Theos_2456 216398d308e1d5186e7ea4b399acf028 160 Pfam PF13411 MerR HTH family regulatory protein 15 81 8.6E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Theos_2456 216398d308e1d5186e7ea4b399acf028 160 SUPERFAMILY SSF46955 15 81 2.01E-16 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_2456 216398d308e1d5186e7ea4b399acf028 160 SMART SM00422 15 84 1.5E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Theos_0099 e1a19ce03308988f3474cd29cf6050f6 167 Gene3D G3DSA:1.20.1260.10 27 167 4.2E-34 T 14-10-2018 IPR012347 Ferritin-like Theos_0099 e1a19ce03308988f3474cd29cf6050f6 167 Pfam PF03713 Domain of unknown function (DUF305) 30 165 2.0E-30 T 14-10-2018 IPR005183 Domain of unknown function DUF305 Theos_1435 aaa44973a10526a1798b70b633bfe4d7 294 SUPERFAMILY SSF53850 21 291 1.24E-46 T 14-10-2018 Theos_1435 aaa44973a10526a1798b70b633bfe4d7 294 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 27 157 2.5E-30 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 Theos_1435 aaa44973a10526a1798b70b633bfe4d7 294 Pfam PF13531 Bacterial extracellular solute-binding protein 22 288 8.8E-39 T 14-10-2018 Theos_1435 aaa44973a10526a1798b70b633bfe4d7 294 Gene3D G3DSA:3.40.190.10 21 141 4.0E-26 T 14-10-2018 Theos_1435 aaa44973a10526a1798b70b633bfe4d7 294 Gene3D G3DSA:3.40.190.10 195 289 1.6E-5 T 14-10-2018 Theos_1435 aaa44973a10526a1798b70b633bfe4d7 294 PIRSF PIRSF004846 5 167 5.7E-26 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 Theos_1435 aaa44973a10526a1798b70b633bfe4d7 294 PIRSF PIRSF004846 182 292 5.4E-10 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 Theos_2469 fef71517bdea3e66e8e1c7e9dcd16d79 257 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 94 247 2.3E-10 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Theos_2469 fef71517bdea3e66e8e1c7e9dcd16d79 257 SUPERFAMILY SSF56529 3 256 1.03E-68 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Theos_2469 fef71517bdea3e66e8e1c7e9dcd16d79 257 Gene3D G3DSA:3.90.850.10 2 257 1.1E-77 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Theos_2196 2cfbcce9d64a4bb650e3b368054b42ce 262 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 196 1.3E-30 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Theos_2196 2cfbcce9d64a4bb650e3b368054b42ce 262 PIRSF PIRSF005917 1 262 4.7E-91 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Theos_2196 2cfbcce9d64a4bb650e3b368054b42ce 262 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 3 256 1.5E-67 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Theos_2196 2cfbcce9d64a4bb650e3b368054b42ce 262 SUPERFAMILY SSF53790 3 213 1.31E-74 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Theos_2196 2cfbcce9d64a4bb650e3b368054b42ce 262 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 2 215 35.155 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Theos_2196 2cfbcce9d64a4bb650e3b368054b42ce 262 Gene3D G3DSA:3.30.950.10 106 220 4.7E-42 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Theos_2196 2cfbcce9d64a4bb650e3b368054b42ce 262 Gene3D G3DSA:3.40.1010.10 1 105 1.6E-31 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 320 2.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 345 2.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 306 2.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 364 2.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 SMART SM00387 255 367 2.9E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 256 365 4.6E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 SUPERFAMILY SSF55874 198 365 4.06E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 Pfam PF00512 His Kinase A (phospho-acceptor) domain 147 208 1.5E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 Gene3D G3DSA:1.10.287.130 92 205 5.1E-22 T 14-10-2018 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 SMART SM00388 146 209 2.3E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 Gene3D G3DSA:3.30.565.10 210 367 5.4E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 SUPERFAMILY SSF158472 101 141 5.23E-5 T 14-10-2018 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 SUPERFAMILY SSF47384 129 209 1.92E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_0094 39a0bcf461f80b1edbe0e3b2fcc1b6fb 373 SMART SM00304 93 145 6.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Theos_1387 bb8b84ff5dba5f91ed4433f68b2c3227 247 SMART SM00382 27 223 1.6E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1387 bb8b84ff5dba5f91ed4433f68b2c3227 247 SUPERFAMILY SSF52540 2 245 2.72E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1387 bb8b84ff5dba5f91ed4433f68b2c3227 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 245 8.4E-6 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Theos_1387 bb8b84ff5dba5f91ed4433f68b2c3227 247 Gene3D G3DSA:3.40.50.300 1 247 2.3E-60 T 14-10-2018 Theos_1387 bb8b84ff5dba5f91ed4433f68b2c3227 247 Pfam PF00005 ABC transporter 18 174 6.4E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0906 daafcbd97c4a96cfd79360039e96779b 290 SUPERFAMILY SSF103378 109 238 1.83E-7 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 Theos_0906 daafcbd97c4a96cfd79360039e96779b 290 Gene3D G3DSA:1.10.4100.10 89 245 1.2E-5 T 14-10-2018 Theos_0906 daafcbd97c4a96cfd79360039e96779b 290 Pfam PF03313 Serine dehydratase alpha chain 16 268 9.5E-71 T 14-10-2018 IPR005130 Serine dehydratase-like, alpha subunit Theos_0906 daafcbd97c4a96cfd79360039e96779b 290 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 16 284 4.6E-78 T 14-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 Theos_0192 7431dab6fda1b581eca5bf36d4997ff2 272 Gene3D G3DSA:3.40.50.300 1 156 5.2E-8 T 14-10-2018 Theos_0192 7431dab6fda1b581eca5bf36d4997ff2 272 SUPERFAMILY SSF52540 2 148 8.34E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0192 7431dab6fda1b581eca5bf36d4997ff2 272 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 271 35.669 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 Theos_0192 7431dab6fda1b581eca5bf36d4997ff2 272 PIRSF PIRSF005052 1 272 1.1E-92 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 Theos_0192 7431dab6fda1b581eca5bf36d4997ff2 272 Pfam PF03668 P-loop ATPase protein family 1 272 7.3E-79 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 Theos_0363 7242755e5e324738f6e35e013a2c2599 107 Gene3D G3DSA:3.30.428.10 1 107 8.8E-39 T 14-10-2018 IPR036265 HIT-like superfamily Theos_0363 7242755e5e324738f6e35e013a2c2599 107 Pfam PF01230 HIT domain 10 104 2.9E-26 T 14-10-2018 IPR001310 Histidine triad (HIT) protein Theos_0363 7242755e5e324738f6e35e013a2c2599 107 PRINTS PR00332 Histidine triad family signature 25 43 5.3E-20 T 14-10-2018 IPR001310 Histidine triad (HIT) protein Theos_0363 7242755e5e324738f6e35e013a2c2599 107 PRINTS PR00332 Histidine triad family signature 93 103 5.3E-20 T 14-10-2018 IPR001310 Histidine triad (HIT) protein Theos_0363 7242755e5e324738f6e35e013a2c2599 107 PRINTS PR00332 Histidine triad family signature 4 20 5.3E-20 T 14-10-2018 IPR001310 Histidine triad (HIT) protein Theos_0363 7242755e5e324738f6e35e013a2c2599 107 SUPERFAMILY SSF54197 1 106 9.12E-34 T 14-10-2018 IPR036265 HIT-like superfamily Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 150 250 1.1E-15 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 SUPERFAMILY SSF53738 149 255 6.67E-20 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 Gene3D G3DSA:3.30.310.50 371 455 4.0E-25 T 14-10-2018 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 SUPERFAMILY SSF53738 241 370 7.06E-28 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 403 451 5.7E-10 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 Gene3D G3DSA:3.40.120.10 254 370 7.5E-42 T 14-10-2018 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 3.6E-8 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 204 217 3.6E-8 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 3.6E-8 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 Gene3D G3DSA:3.40.120.10 169 253 3.5E-20 T 14-10-2018 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 363 4.6E-22 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 Gene3D G3DSA:3.40.120.10 1 144 2.4E-49 T 14-10-2018 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 SUPERFAMILY SSF53738 3 162 1.27E-42 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 132 1.1E-36 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0461 7f82900b0710ba55c30b6bb08e2aa122 458 SUPERFAMILY SSF55957 395 455 7.98E-18 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_2235 e4be460c84fc7889e374c6be87ee725b 235 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2235 e4be460c84fc7889e374c6be87ee725b 235 Pfam PF00005 ABC transporter 17 163 2.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2235 e4be460c84fc7889e374c6be87ee725b 235 SUPERFAMILY SSF52540 2 232 5.99E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2235 e4be460c84fc7889e374c6be87ee725b 235 SMART SM00382 26 221 7.8E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2235 e4be460c84fc7889e374c6be87ee725b 235 Gene3D G3DSA:3.40.50.300 1 235 1.9E-56 T 14-10-2018 Theos_1651 ec9ce2a5bc03d3c5a298bfe0da247e6c 182 Gene3D G3DSA:3.30.420.40 4 110 2.1E-25 T 14-10-2018 Theos_1651 ec9ce2a5bc03d3c5a298bfe0da247e6c 182 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 7 152 2.1E-33 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 Theos_1651 ec9ce2a5bc03d3c5a298bfe0da247e6c 182 SUPERFAMILY SSF53067 6 105 5.18E-20 T 14-10-2018 Theos_1651 ec9ce2a5bc03d3c5a298bfe0da247e6c 182 Pfam PF00814 Glycoprotease family 33 129 3.8E-17 T 14-10-2018 IPR000905 Gcp-like domain Theos_0403 5368eb7fbaff1454434b1bf42e1d3fa1 517 SUPERFAMILY SSF161098 279 513 1.4E-36 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0403 5368eb7fbaff1454434b1bf42e1d3fa1 517 Gene3D G3DSA:1.10.3720.10 13 258 1.6E-51 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0403 5368eb7fbaff1454434b1bf42e1d3fa1 517 Gene3D G3DSA:1.10.3720.10 277 516 1.9E-35 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0403 5368eb7fbaff1454434b1bf42e1d3fa1 517 SUPERFAMILY SSF161098 10 264 6.64E-43 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0403 5368eb7fbaff1454434b1bf42e1d3fa1 517 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 243 5.0E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0403 5368eb7fbaff1454434b1bf42e1d3fa1 517 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 341 510 5.8E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0903 c0747cff35e8f88c4cd4d9c97c38599f 239 Gene3D G3DSA:3.40.1280.10 1 160 9.2E-58 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Theos_0903 c0747cff35e8f88c4cd4d9c97c38599f 239 PIRSF PIRSF000386 1 238 1.2E-91 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Theos_0903 c0747cff35e8f88c4cd4d9c97c38599f 239 SUPERFAMILY SSF75217 2 237 2.75E-84 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Theos_0903 c0747cff35e8f88c4cd4d9c97c38599f 239 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 239 93.952 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Theos_0903 c0747cff35e8f88c4cd4d9c97c38599f 239 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 2 222 3.7E-79 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Theos_0903 c0747cff35e8f88c4cd4d9c97c38599f 239 Gene3D G3DSA:1.10.1270.20 161 239 9.6E-28 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Theos_0903 c0747cff35e8f88c4cd4d9c97c38599f 239 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 216 8.6E-58 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Theos_0215 f3ae412766577e3ad599cc118187b619 304 Pfam PF02911 Formyl transferase, C-terminal domain 201 295 3.5E-28 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Theos_0215 f3ae412766577e3ad599cc118187b619 304 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 295 2.7E-75 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Theos_0215 f3ae412766577e3ad599cc118187b619 304 SUPERFAMILY SSF53328 1 202 1.27E-58 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Theos_0215 f3ae412766577e3ad599cc118187b619 304 Gene3D G3DSA:3.40.50.170 1 202 2.8E-69 T 14-10-2018 Theos_0215 f3ae412766577e3ad599cc118187b619 304 Gene3D G3DSA:3.10.25.10 203 301 2.7E-25 T 14-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Theos_0215 f3ae412766577e3ad599cc118187b619 304 SUPERFAMILY SSF50486 201 303 5.34E-29 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 Theos_0215 f3ae412766577e3ad599cc118187b619 304 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 298 33.263 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Theos_0215 f3ae412766577e3ad599cc118187b619 304 Pfam PF00551 Formyl transferase 1 180 9.2E-44 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Theos_0215 f3ae412766577e3ad599cc118187b619 304 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 132 155 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Theos_1442 a4df1163207fab1e8b9a545b53a2b0c9 297 Pfam PF02567 Phenazine biosynthesis-like protein 9 295 1.2E-53 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 Theos_1442 a4df1163207fab1e8b9a545b53a2b0c9 297 SUPERFAMILY SSF54506 3 297 7.86E-55 T 14-10-2018 Theos_1442 a4df1163207fab1e8b9a545b53a2b0c9 297 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 296 6.6E-45 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 Theos_1442 a4df1163207fab1e8b9a545b53a2b0c9 297 PIRSF PIRSF016184 1 297 2.6E-65 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 Theos_1442 a4df1163207fab1e8b9a545b53a2b0c9 297 Gene3D G3DSA:3.10.310.10 2 132 7.6E-27 T 14-10-2018 Theos_1442 a4df1163207fab1e8b9a545b53a2b0c9 297 Gene3D G3DSA:3.10.310.10 133 288 2.2E-38 T 14-10-2018 Theos_1258 fe054da6358e214d0ff4799eeb359c73 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 251 2.8E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1258 fe054da6358e214d0ff4799eeb359c73 259 Gene3D G3DSA:1.10.3720.10 1 259 1.8E-60 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1258 fe054da6358e214d0ff4799eeb359c73 259 SUPERFAMILY SSF161098 10 250 2.62E-58 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0007 1d7caacffecc49d4b0bd2fae5302af02 183 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 2 182 8.7E-66 T 14-10-2018 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0007 1d7caacffecc49d4b0bd2fae5302af02 183 Gene3D G3DSA:3.40.50.2020 1 182 5.3E-53 T 14-10-2018 Theos_0007 1d7caacffecc49d4b0bd2fae5302af02 183 SUPERFAMILY SSF53271 3 177 6.67E-32 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_0007 1d7caacffecc49d4b0bd2fae5302af02 183 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 183 23.435 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0007 1d7caacffecc49d4b0bd2fae5302af02 183 Pfam PF00156 Phosphoribosyl transferase domain 33 148 3.1E-12 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 Gene3D G3DSA:2.40.50.140 132 228 5.5E-15 T 14-10-2018 Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 SUPERFAMILY SSF52540 272 525 1.28E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 SUPERFAMILY SSF50249 104 261 2.91E-38 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 SMART SM00490 576 660 1.7E-22 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 SUPERFAMILY SSF52540 524 724 2.13E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 113 734 3.8E-217 T 14-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 SMART SM00487 340 531 7.4E-30 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 Gene3D G3DSA:3.40.50.300 325 528 1.7E-82 T 14-10-2018 Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 Pfam PF17191 RecG wedge domain 105 257 3.3E-21 T 14-10-2018 IPR033454 RecG, wedge domain Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 Pfam PF00270 DEAD/DEAH box helicase 348 503 3.1E-16 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 Pfam PF00271 Helicase conserved C-terminal domain 549 660 1.3E-19 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1285 f9a202de620fbb93c07cae97bebb95d5 770 Gene3D G3DSA:3.40.50.300 529 700 9.0E-57 T 14-10-2018 Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 193 2.7E-24 T 14-10-2018 Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 Gene3D G3DSA:1.10.150.240 18 95 3.1E-63 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 9.3E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 177 9.3E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 184 197 9.3E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 9.3E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 9.3E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 Gene3D G3DSA:3.40.50.1000 6 211 3.1E-63 T 14-10-2018 IPR023214 HAD superfamily Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 SUPERFAMILY SSF56784 4 216 1.28E-42 T 14-10-2018 IPR036412 HAD-like superfamily Theos_1742 8e318f87d2f44597bb3909b1b88d4481 250 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 80 192 7.7E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 SUPERFAMILY SSF82693 627 716 8.37E-9 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Gene3D G3DSA:3.30.70.1320 137 322 3.8E-133 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Gene3D G3DSA:3.30.70.1430 630 720 2.1E-100 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Gene3D G3DSA:1.20.1640.10 493 533 3.8E-133 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 SUPERFAMILY SSF82866 859 1083 1.96E-39 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Pfam PF00873 AcrB/AcrD/AcrF family 8 478 2.9E-111 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Pfam PF00873 AcrB/AcrD/AcrF family 574 1078 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Gene3D G3DSA:1.20.1640.10 15 492 3.8E-133 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 SUPERFAMILY SSF82714 774 851 5.36E-10 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Gene3D G3DSA:3.30.2090.10 771 860 2.1E-100 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Gene3D G3DSA:3.30.2090.10 182 271 3.8E-133 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 SUPERFAMILY SSF82693 44 137 9.55E-23 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Gene3D G3DSA:3.30.70.1440 721 924 2.1E-100 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 SUPERFAMILY SSF82866 289 485 9.29E-38 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 SUPERFAMILY SSF82714 187 264 1.18E-7 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Gene3D G3DSA:1.20.1640.10 575 1077 2.1E-100 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 PRINTS PR00702 Acriflavin resistance protein family signature 14 38 1.2E-34 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 1.2E-34 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 1.2E-34 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 1.2E-34 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 PRINTS PR00702 Acriflavin resistance protein family signature 42 60 1.2E-34 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 1.2E-34 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 1.2E-34 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 SUPERFAMILY SSF82693 139 321 1.43E-17 T 14-10-2018 Theos_2439 b680c8e08d76f1a7a2dd975cbcaf44f0 1095 Gene3D G3DSA:3.30.70.1430 44 136 3.8E-133 T 14-10-2018 Theos_2443 f7fae61a807eecd12918e58c1b0fc6b5 269 Gene3D G3DSA:3.50.30.50 32 269 1.3E-79 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Theos_2443 f7fae61a807eecd12918e58c1b0fc6b5 269 Pfam PF04199 Putative cyclase 46 211 4.7E-35 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Theos_2443 f7fae61a807eecd12918e58c1b0fc6b5 269 SUPERFAMILY SSF102198 43 268 3.14E-58 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 9.6E-16 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 Gene3D G3DSA:2.40.30.10 350 405 7.8E-30 T 14-10-2018 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 SUPERFAMILY SSF52540 6 230 6.44E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1951 c1860e4059ace35f95e19456acaf814b 406 Pfam PF03143 Elongation factor Tu C-terminal domain 310 404 4.0E-35 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Theos_1951 c1860e4059ace35f95e19456acaf814b 406 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Theos_1951 c1860e4059ace35f95e19456acaf814b 406 SUPERFAMILY SSF50447 216 313 4.32E-32 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_1951 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 132 141 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 59 67 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 Gene3D G3DSA:2.40.30.10 217 346 1.1E-58 T 14-10-2018 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 406 2.3E-223 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 Pfam PF00009 Elongation factor Tu GTP binding domain 10 212 9.5E-62 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 406 61.427 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 Gene3D G3DSA:3.40.50.300 3 214 1.0E-71 T 14-10-2018 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 Pfam PF03144 Elongation factor Tu domain 2 236 305 1.9E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Theos_1951 c1860e4059ace35f95e19456acaf814b 406 SUPERFAMILY SSF50465 310 405 9.5E-37 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Theos_0275 c1860e4059ace35f95e19456acaf814b 406 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 9.6E-16 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 Gene3D G3DSA:2.40.30.10 350 405 7.8E-30 T 14-10-2018 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 SUPERFAMILY SSF52540 6 230 6.44E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0275 c1860e4059ace35f95e19456acaf814b 406 Pfam PF03143 Elongation factor Tu C-terminal domain 310 404 4.0E-35 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Theos_0275 c1860e4059ace35f95e19456acaf814b 406 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Theos_0275 c1860e4059ace35f95e19456acaf814b 406 SUPERFAMILY SSF50447 216 313 4.32E-32 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_0275 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 132 141 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 PRINTS PR00315 GTP-binding elongation factor signature 59 67 6.4E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 Gene3D G3DSA:2.40.30.10 217 346 1.1E-58 T 14-10-2018 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 406 2.3E-223 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 Pfam PF00009 Elongation factor Tu GTP binding domain 10 212 9.5E-62 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 406 61.427 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 Gene3D G3DSA:3.40.50.300 3 214 1.0E-71 T 14-10-2018 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 Pfam PF03144 Elongation factor Tu domain 2 236 305 1.9E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Theos_0275 c1860e4059ace35f95e19456acaf814b 406 SUPERFAMILY SSF50465 310 405 9.5E-37 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Theos_1597 93eaf4be5d08f1871a82744218b337da 289 TIGRFAM TIGR00191 thrB: homoserine kinase 5 269 6.8E-60 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 Theos_1597 93eaf4be5d08f1871a82744218b337da 289 Hamap MF_00384 Homoserine kinase [thrB]. 4 288 27.076 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 Theos_1597 93eaf4be5d08f1871a82744218b337da 289 Pfam PF00288 GHMP kinases N terminal domain 79 135 3.8E-10 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Theos_1597 93eaf4be5d08f1871a82744218b337da 289 SUPERFAMILY SSF54211 3 149 5.77E-26 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_1597 93eaf4be5d08f1871a82744218b337da 289 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 81 92 - T 14-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 Theos_1597 93eaf4be5d08f1871a82744218b337da 289 Gene3D G3DSA:3.30.70.890 150 275 6.3E-38 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Theos_1597 93eaf4be5d08f1871a82744218b337da 289 Pfam PF08544 GHMP kinases C terminal 200 267 5.2E-8 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain Theos_1597 93eaf4be5d08f1871a82744218b337da 289 SUPERFAMILY SSF55060 155 271 1.18E-29 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Theos_1597 93eaf4be5d08f1871a82744218b337da 289 PIRSF PIRSF000676 1 284 8.5E-73 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 Theos_1597 93eaf4be5d08f1871a82744218b337da 289 Gene3D G3DSA:3.30.230.10 3 145 7.9E-38 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_1597 93eaf4be5d08f1871a82744218b337da 289 PRINTS PR00958 Homoserine kinase signature 159 176 3.0E-33 T 14-10-2018 Theos_1597 93eaf4be5d08f1871a82744218b337da 289 PRINTS PR00958 Homoserine kinase signature 9 24 3.0E-33 T 14-10-2018 Theos_1597 93eaf4be5d08f1871a82744218b337da 289 PRINTS PR00958 Homoserine kinase signature 122 135 3.0E-33 T 14-10-2018 Theos_1597 93eaf4be5d08f1871a82744218b337da 289 PRINTS PR00958 Homoserine kinase signature 88 103 3.0E-33 T 14-10-2018 Theos_1597 93eaf4be5d08f1871a82744218b337da 289 PRINTS PR00958 Homoserine kinase signature 238 253 3.0E-33 T 14-10-2018 Theos_0532 888fc1c7ab30ad0f2875e579a191cb61 208 SUPERFAMILY SSF53271 4 206 1.18E-69 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_0532 888fc1c7ab30ad0f2875e579a191cb61 208 Pfam PF14681 Uracil phosphoribosyltransferase 6 207 4.7E-72 T 14-10-2018 Theos_0532 888fc1c7ab30ad0f2875e579a191cb61 208 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 208 5.6E-85 T 14-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 Theos_0532 888fc1c7ab30ad0f2875e579a191cb61 208 Gene3D G3DSA:3.40.50.2020 1 208 7.2E-81 T 14-10-2018 Theos_0532 888fc1c7ab30ad0f2875e579a191cb61 208 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 45.443 T 14-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 Pfam PF00009 Elongation factor Tu GTP binding domain 2 267 1.2E-31 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 Gene3D G3DSA:3.30.70.240 567 637 2.8E-78 T 14-10-2018 Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 Pfam PF14492 Elongation Factor G, domain II 371 442 1.5E-22 T 14-10-2018 Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 SUPERFAMILY SSF50447 251 363 4.89E-17 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 SUPERFAMILY SSF52540 2 267 9.22E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 Gene3D G3DSA:3.40.50.300 1 273 7.2E-74 T 14-10-2018 Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 SUPERFAMILY SSF54980 563 653 8.15E-24 T 14-10-2018 IPR035647 EF-G domain III/V-like Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 Gene3D G3DSA:3.30.230.10 450 650 2.8E-78 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 Pfam PF03764 Elongation factor G, domain IV 445 561 7.0E-38 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 141 1.4E-12 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 SUPERFAMILY SSF54980 372 447 1.15E-18 T 14-10-2018 IPR035647 EF-G domain III/V-like Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 SMART SM00838 563 650 1.2E-31 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 SUPERFAMILY SSF54211 448 562 2.3E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 Gene3D G3DSA:3.30.70.870 371 446 1.6E-22 T 14-10-2018 Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 Pfam PF00679 Elongation factor G C-terminus 563 649 2.2E-25 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 SMART SM00889 446 561 6.3E-61 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Theos_0369 a0b023a666d2d1601a49733ce07492ff 657 Gene3D G3DSA:2.40.30.10 274 370 8.4E-19 T 14-10-2018 Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 Pfam PF03461 TRCF domain 844 928 1.3E-19 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 SMART SM00490 667 751 2.1E-15 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 Pfam PF00271 Helicase conserved C-terminal domain 649 750 6.6E-13 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 SUPERFAMILY SSF52540 623 829 1.11E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 SUPERFAMILY SSF52540 369 625 5.0E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 Pfam PF00270 DEAD/DEAH box helicase 446 603 3.8E-15 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 315 916 1.7E-252 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 Gene3D G3DSA:3.90.1150.50 840 960 5.3E-19 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 Pfam PF02559 CarD-like/TRCF domain 321 413 2.9E-24 T 14-10-2018 IPR003711 CarD-like/TRCF domain Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 Gene3D G3DSA:3.40.50.300 320 829 2.5E-211 T 14-10-2018 Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 SUPERFAMILY SSF143517 834 947 5.75E-22 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 Gene3D G3DSA:2.30.30.840 324 382 2.5E-211 T 14-10-2018 Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 SUPERFAMILY SSF52540 23 143 7.61E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 SMART SM00982 843 944 7.8E-23 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 SMART SM00487 441 631 8.3E-33 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 Gene3D G3DSA:3.40.50.300 383 622 2.5E-211 T 14-10-2018 Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 SMART SM01058 320 417 3.8E-37 T 14-10-2018 IPR003711 CarD-like/TRCF domain Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 16 925 24.421 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Theos_1542 dcdde7b330523bc8c3bbab05182400ac 984 SUPERFAMILY SSF141259 315 389 9.42E-20 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily Theos_1330 397b0d9e0d635425c6226749bf661de4 234 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 3 233 1.4E-92 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 Theos_1330 397b0d9e0d635425c6226749bf661de4 234 Pfam PF00696 Amino acid kinase family 4 212 6.2E-31 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Theos_1330 397b0d9e0d635425c6226749bf661de4 234 Gene3D G3DSA:3.40.1160.10 1 234 5.2E-82 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_1330 397b0d9e0d635425c6226749bf661de4 234 Hamap MF_01220_B Uridylate kinase [pyrH]. 1 233 44.525 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 Theos_1330 397b0d9e0d635425c6226749bf661de4 234 PIRSF PIRSF005650 1 234 4.9E-95 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 Theos_1330 397b0d9e0d635425c6226749bf661de4 234 SUPERFAMILY SSF53633 1 234 3.67E-75 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_0799 f577f5ac43014cfe8487cc6cfcbed52a 250 SUPERFAMILY SSF88713 1 250 1.93E-93 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Theos_0799 f577f5ac43014cfe8487cc6cfcbed52a 250 Pfam PF03746 LamB/YcsF family 3 240 6.0E-95 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 Theos_0799 f577f5ac43014cfe8487cc6cfcbed52a 250 Gene3D G3DSA:3.20.20.370 1 250 1.2E-102 T 14-10-2018 Theos_0799 f577f5ac43014cfe8487cc6cfcbed52a 250 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 43.563 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 119 135 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 154 3.3E-24 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 6 154 2.7E-52 T 14-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 SUPERFAMILY SSF54534 84 154 3.53E-17 T 14-10-2018 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 Pfam PF03449 Transcription elongation factor, N-terminal 5 75 9.5E-27 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 Hamap MF_00105 Transcription elongation factor GreA [greA]. 3 154 26.806 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 SUPERFAMILY SSF46557 4 77 1.01E-22 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 Gene3D G3DSA:1.10.287.180 2 76 2.8E-25 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 PIRSF PIRSF006092 1 156 3.6E-54 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 Theos_1340 c9d73cdf4a7a904fa4067a65e62506cb 156 Gene3D G3DSA:3.10.50.30 80 150 2.0E-21 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 Gene3D G3DSA:1.10.730.10 3 734 0.0 T 14-10-2018 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 SUPERFAMILY SSF50677 192 339 1.83E-53 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 SUPERFAMILY SSF46589 797 861 1.78E-10 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 Gene3D G3DSA:1.10.287.380 790 862 2.9E-26 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 TIGRFAM TIGR00422 valS: valine--tRNA ligase 4 843 5.7E-297 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 Hamap MF_02004 Valine--tRNA ligase [valS]. 3 862 14.64 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 Gene3D G3DSA:3.30.1170.10 740 789 7.3E-23 T 14-10-2018 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 Pfam PF08264 Anticodon-binding domain of tRNA 607 747 3.1E-36 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 797 861 6.7E-19 T 14-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 SUPERFAMILY SSF47323 579 794 1.51E-50 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 SUPERFAMILY SSF52374 2 578 6.14E-142 T 14-10-2018 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 Gene3D G3DSA:3.40.50.620 23 529 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1186 068d90b93195bfbcb77673f981cbad53 862 Gene3D G3DSA:3.90.740.10 175 343 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 PRINTS PR00986 Valyl-tRNA synthetase signature 480 498 6.4E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 PRINTS PR00986 Valyl-tRNA synthetase signature 229 246 6.4E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 PRINTS PR00986 Valyl-tRNA synthetase signature 346 359 6.4E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 PRINTS PR00986 Valyl-tRNA synthetase signature 449 470 6.4E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 6.4E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Theos_1186 068d90b93195bfbcb77673f981cbad53 862 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 568 1.1E-185 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_2424 88d3aa1405866f241c06edc21dbf3140 120 Gene3D G3DSA:3.30.450.30 4 120 6.5E-30 T 14-10-2018 Theos_2424 88d3aa1405866f241c06edc21dbf3140 120 SMART SM00960 7 96 1.1E-21 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain Theos_2424 88d3aa1405866f241c06edc21dbf3140 120 Pfam PF03259 Roadblock/LC7 domain 9 95 8.9E-18 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain Theos_2424 88d3aa1405866f241c06edc21dbf3140 120 SUPERFAMILY SSF103196 3 120 1.99E-24 T 14-10-2018 Theos_1814 ce71a68494b8149e3e1ceb969adff0de 478 Pfam PF03477 ATP cone domain 185 258 6.7E-5 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 Theos_1814 ce71a68494b8149e3e1ceb969adff0de 478 Gene3D G3DSA:3.40.50.300 261 463 1.3E-8 T 14-10-2018 Theos_1814 ce71a68494b8149e3e1ceb969adff0de 478 SUPERFAMILY SSF52540 262 464 8.19E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 Gene3D G3DSA:3.40.50.1220 184 347 1.2E-63 T 14-10-2018 Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 SUPERFAMILY SSF52518 1 168 7.15E-63 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 323 1.8E-47 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 551 8.4E-242 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 Gene3D G3DSA:3.40.50.970 1 174 6.4E-70 T 14-10-2018 Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 SUPERFAMILY SSF52467 183 349 2.89E-62 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 7.9E-57 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 416 435 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 Gene3D G3DSA:3.40.50.970 352 561 1.1E-68 T 14-10-2018 Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 527 2.4E-50 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Theos_1231 77b2d7fe5d35264639162c6241b8f2f1 562 SUPERFAMILY SSF52518 356 556 7.51E-68 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 Gene3D G3DSA:3.40.50.300 308 497 1.2E-66 T 14-10-2018 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 5 196 1.8E-37 T 14-10-2018 IPR003111 Lon, substrate-binding domain Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 576 778 1.3E-91 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 Gene3D G3DSA:1.10.8.60 498 590 1.4E-31 T 14-10-2018 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 Gene3D G3DSA:2.30.130.40 1 111 4.5E-29 T 14-10-2018 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 PIRSF PIRSF001174 2 780 0.0 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 SMART SM00464 5 197 1.4E-62 T 14-10-2018 IPR003111 Lon, substrate-binding domain Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 SMART SM00382 354 502 3.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 732 750 5.5E-49 T 14-10-2018 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 362 381 5.5E-49 T 14-10-2018 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 679 698 5.5E-49 T 14-10-2018 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 601 617 5.5E-49 T 14-10-2018 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 709 728 5.5E-49 T 14-10-2018 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 SUPERFAMILY SSF54211 601 776 7.97E-56 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 Gene3D G3DSA:1.20.58.1480 117 240 2.2E-37 T 14-10-2018 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 Gene3D G3DSA:3.30.230.10 599 789 3.7E-80 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 TIGRFAM TIGR00763 lon: endopeptidase La 8 777 2.0E-288 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 Hamap MF_01973 Lon protease [lon]. 6 778 70.508 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 SUPERFAMILY SSF52540 307 590 5.8E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 358 497 4.3E-23 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_1476 88f7dcace5a6e6608af1dc799b3c1629 806 SUPERFAMILY SSF88697 5 196 2.36E-39 T 14-10-2018 IPR015947 PUA-like superfamily Theos_1646 2c4d6dcdd61958f12540cde1c010c430 224 Pfam PF01882 Protein of unknown function DUF58 26 83 7.8E-16 T 14-10-2018 IPR002881 Domain of unknown function DUF58 Theos_2446 60865aa25c1b4001473c1a48dd6912d5 311 SUPERFAMILY SSF161098 93 297 1.07E-19 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2446 60865aa25c1b4001473c1a48dd6912d5 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 309 2.8E-37 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2446 60865aa25c1b4001473c1a48dd6912d5 311 Gene3D G3DSA:1.10.3720.10 87 303 1.2E-20 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1787 d9b0285a3be9aae29ab81c11d3bc2770 693 Gene3D G3DSA:1.10.10.160 114 192 1.9E-98 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily Theos_1787 d9b0285a3be9aae29ab81c11d3bc2770 693 Gene3D G3DSA:3.40.50.300 283 617 9.5E-112 T 14-10-2018 Theos_1787 d9b0285a3be9aae29ab81c11d3bc2770 693 Gene3D G3DSA:3.40.50.300 14 275 1.9E-98 T 14-10-2018 Theos_1787 d9b0285a3be9aae29ab81c11d3bc2770 693 Gene3D G3DSA:1.10.486.10 382 532 9.5E-112 T 14-10-2018 Theos_1787 d9b0285a3be9aae29ab81c11d3bc2770 693 Pfam PF13361 UvrD-like helicase C-terminal domain 280 427 1.1E-35 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Theos_1787 d9b0285a3be9aae29ab81c11d3bc2770 693 SUPERFAMILY SSF52540 7 624 3.6E-170 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1787 d9b0285a3be9aae29ab81c11d3bc2770 693 Pfam PF13361 UvrD-like helicase C-terminal domain 490 600 2.8E-30 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Theos_1787 d9b0285a3be9aae29ab81c11d3bc2770 693 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 274 2.9E-69 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Theos_0394 42c8bacded7ea6e241338f132fe2ef36 236 SUPERFAMILY SSF53474 10 232 4.49E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_0394 42c8bacded7ea6e241338f132fe2ef36 236 Gene3D G3DSA:3.40.50.1820 1 234 2.8E-62 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1194 36bc3566ac9f55b58f84a86535cc1d58 281 Gene3D G3DSA:3.40.1790.10 2 281 1.3E-92 T 14-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Theos_1194 36bc3566ac9f55b58f84a86535cc1d58 281 SUPERFAMILY SSF110581 4 277 1.28E-87 T 14-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Theos_1194 36bc3566ac9f55b58f84a86535cc1d58 281 Pfam PF04227 Indigoidine synthase A like protein 4 274 3.4E-93 T 14-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Theos_1194 36bc3566ac9f55b58f84a86535cc1d58 281 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 2 279 34.387 T 14-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Theos_0333 225a24f181b1c83073d4e271fe7ec94a 134 Pfam PF13470 PIN domain 2 106 6.8E-9 T 14-10-2018 IPR002716 PIN domain Theos_0333 225a24f181b1c83073d4e271fe7ec94a 134 SUPERFAMILY SSF88723 2 112 1.67E-8 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_1924 e6eabe21a54ed070d8ac9d654cfb55fd 233 Gene3D G3DSA:3.50.50.60 1 233 5.2E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1924 e6eabe21a54ed070d8ac9d654cfb55fd 233 SUPERFAMILY SSF51905 3 194 1.84E-24 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1924 e6eabe21a54ed070d8ac9d654cfb55fd 233 Pfam PF01134 Glucose inhibited division protein A 70 169 9.5E-12 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 Theos_1924 e6eabe21a54ed070d8ac9d654cfb55fd 233 Pfam PF01134 Glucose inhibited division protein A 5 40 1.7E-6 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 Theos_2230 58e3df46183a1b2446c858198cc24080 323 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 157 275 4.3E-15 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Theos_2230 58e3df46183a1b2446c858198cc24080 323 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 124 2.6E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Theos_2230 58e3df46183a1b2446c858198cc24080 323 Gene3D G3DSA:3.10.180.10 13 147 1.0E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_2230 58e3df46183a1b2446c858198cc24080 323 SUPERFAMILY SSF54593 13 278 1.47E-42 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_2230 58e3df46183a1b2446c858198cc24080 323 Gene3D G3DSA:3.10.180.10 156 323 1.2E-45 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_2230 58e3df46183a1b2446c858198cc24080 323 TIGRFAM TIGR03211 catechol_2_3: catechol 2,3 dioxygenase 14 317 7.2E-100 T 14-10-2018 IPR017624 Catechol 2,3 dioxygenase GO:0008198|GO:0018577|GO:0019439|GO:0055114 KEGG: 00361+1.13.11.2|KEGG: 00362+1.13.11.2|KEGG: 00622+1.13.11.2|KEGG: 00643+1.13.11.2|MetaCyc: PWY-5419|MetaCyc: PWY-5641 Theos_1291 b2b23a377824863c357271984726f373 333 Gene3D G3DSA:3.90.230.10 101 318 1.7E-21 T 14-10-2018 Theos_1291 b2b23a377824863c357271984726f373 333 SUPERFAMILY SSF55920 103 316 7.2E-22 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like Theos_1291 b2b23a377824863c357271984726f373 333 Pfam PF00557 Metallopeptidase family M24 114 302 2.4E-12 T 14-10-2018 IPR000994 Peptidase M24 Theos_1291 b2b23a377824863c357271984726f373 333 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 81 2.5E-5 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 Theos_1878 9a76ad644004409012340db17ba37704 233 SMART SM00448 2 113 3.4E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_1878 9a76ad644004409012340db17ba37704 233 SUPERFAMILY SSF52172 1 172 1.61E-40 T 14-10-2018 IPR011006 CheY-like superfamily Theos_1878 9a76ad644004409012340db17ba37704 233 Gene3D G3DSA:3.40.50.2300 1 118 6.4E-37 T 14-10-2018 Theos_1878 9a76ad644004409012340db17ba37704 233 Gene3D G3DSA:1.10.10.10 119 226 2.5E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1878 9a76ad644004409012340db17ba37704 233 SMART SM00862 144 220 1.8E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_1878 9a76ad644004409012340db17ba37704 233 Pfam PF00072 Response regulator receiver domain 4 114 2.7E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_1878 9a76ad644004409012340db17ba37704 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 1.5E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 SUPERFAMILY SSF81901 452 655 7.98E-8 T 14-10-2018 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 Gene3D G3DSA:1.25.40.10 251 343 4.1E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 SUPERFAMILY SSF48452 281 388 1.94E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 811 907 4.8E-7 T 14-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 SMART SM00028 514 547 30.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 SMART SM00028 710 743 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 SMART SM00028 305 338 0.045 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 SUPERFAMILY SSF48452 340 760 2.69E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 Gene3D G3DSA:3.40.50.150 49 212 7.0E-8 T 14-10-2018 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 SUPERFAMILY SSF53335 55 235 2.09E-13 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 Pfam PF13432 Tetratricopeptide repeat 340 393 1.2E-4 T 14-10-2018 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 Pfam PF13432 Tetratricopeptide repeat 502 544 0.0033 T 14-10-2018 Theos_0632 30cd60cd4b70fd1139712712ed3e47f0 922 Pfam PF13432 Tetratricopeptide repeat 278 334 0.0033 T 14-10-2018 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 2 499 6.4E-230 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 Gene3D G3DSA:3.30.420.40 1 255 3.3E-111 T 14-10-2018 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 453 7.3E-68 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 PIRSF PIRSF000538 1 502 6.7E-173 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 Gene3D G3DSA:3.30.420.40 256 502 3.5E-96 T 14-10-2018 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 2 254 1.8E-81 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 Hamap MF_00186 Glycerol kinase [glpK]. 1 500 56.747 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 SUPERFAMILY SSF53067 257 500 9.5E-88 T 14-10-2018 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 SUPERFAMILY SSF53067 2 257 7.69E-95 T 14-10-2018 Theos_0837 a144127fbb74d391ec614f7e06ef6ecb 502 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Theos_2382 aa7743a9bc47f0db6d97d395ce40fb24 499 PIRSF PIRSF001267 1 487 8.9E-86 T 14-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 Theos_2382 aa7743a9bc47f0db6d97d395ce40fb24 499 Pfam PF02541 Ppx/GppA phosphatase family 18 299 2.4E-49 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 Theos_2382 aa7743a9bc47f0db6d97d395ce40fb24 499 SUPERFAMILY SSF53067 126 300 2.81E-39 T 14-10-2018 Theos_2382 aa7743a9bc47f0db6d97d395ce40fb24 499 Gene3D G3DSA:3.30.420.150 126 301 1.7E-43 T 14-10-2018 Theos_2382 aa7743a9bc47f0db6d97d395ce40fb24 499 Gene3D G3DSA:1.10.3210.10 307 498 3.4E-42 T 14-10-2018 Theos_2382 aa7743a9bc47f0db6d97d395ce40fb24 499 SUPERFAMILY SSF53067 3 124 9.71E-27 T 14-10-2018 Theos_2382 aa7743a9bc47f0db6d97d395ce40fb24 499 SUPERFAMILY SSF109604 309 497 7.99E-48 T 14-10-2018 Theos_2382 aa7743a9bc47f0db6d97d395ce40fb24 499 Pfam PF01966 HD domain 328 443 9.0E-11 T 14-10-2018 IPR006674 HD domain Theos_2382 aa7743a9bc47f0db6d97d395ce40fb24 499 Gene3D G3DSA:3.30.420.40 1 122 4.9E-29 T 14-10-2018 Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 SMART SM00861 511 715 0.009 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 SUPERFAMILY SSF52922 722 901 2.57E-47 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 PIRSF PIRSF000156 9 904 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 Gene3D G3DSA:3.40.50.970 68 488 2.5E-125 T 14-10-2018 Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 Gene3D G3DSA:3.40.50.970 489 721 2.3E-100 T 14-10-2018 Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 SUPERFAMILY SSF52518 491 716 2.5E-87 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 SUPERFAMILY SSF52518 69 483 1.44E-125 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 23 902 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 93 310 1.4E-8 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 377 445 2.2E-4 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Theos_2159 3e039447c8acc3d7da0ded8fdc416cb4 904 Gene3D G3DSA:3.40.50.920 726 903 6.4E-60 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 PIRSF PIRSF002191 1 137 5.9E-47 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 6 112 5.6E-39 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 4 116 26.228 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 Pfam PF01245 Ribosomal protein L19 6 113 8.5E-43 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 SUPERFAMILY SSF50104 4 124 3.31E-42 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 Gene3D G3DSA:2.30.30.790 8 120 4.9E-20 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 ProSitePatterns PS01015 Ribosomal protein L19 signature. 88 103 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 PRINTS PR00061 Ribosomal protein L19 signature 36 65 1.7E-37 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 PRINTS PR00061 Ribosomal protein L19 signature 6 35 1.7E-37 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0904 85a4a098b1946401d0ec5d65a2a4ab6a 142 PRINTS PR00061 Ribosomal protein L19 signature 66 89 1.7E-37 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0497 cd290e46ab74011944758b950c469582 209 SMART SM00563 39 151 3.6E-36 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Theos_0497 cd290e46ab74011944758b950c469582 209 Pfam PF01553 Acyltransferase 27 148 8.1E-26 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Theos_0497 cd290e46ab74011944758b950c469582 209 SUPERFAMILY SSF69593 12 204 2.35E-51 T 14-10-2018 Theos_0587 7848c94929ddbf298ecf98e0268f6b97 295 SUPERFAMILY SSF53328 11 193 2.09E-54 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Theos_0587 7848c94929ddbf298ecf98e0268f6b97 295 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 11 193 31.042 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Theos_0587 7848c94929ddbf298ecf98e0268f6b97 295 Pfam PF00551 Formyl transferase 11 187 1.4E-48 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Theos_0587 7848c94929ddbf298ecf98e0268f6b97 295 Gene3D G3DSA:3.40.50.170 4 195 4.2E-69 T 14-10-2018 Theos_0587 7848c94929ddbf298ecf98e0268f6b97 295 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 10 191 3.2E-58 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Theos_2331 2998e2e97643af32e388efed87387263 639 SUPERFAMILY SSF52540 478 636 3.24E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2331 2998e2e97643af32e388efed87387263 639 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 479 636 9.8E-52 T 14-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 Theos_2331 2998e2e97643af32e388efed87387263 639 Gene3D G3DSA:3.40.50.880 245 400 4.2E-13 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_2331 2998e2e97643af32e388efed87387263 639 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 457 115.52 T 14-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 Theos_2331 2998e2e97643af32e388efed87387263 639 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 247 393 1.3E-23 T 14-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 Theos_2331 2998e2e97643af32e388efed87387263 639 SUPERFAMILY SSF52317 191 403 1.2E-21 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_2331 2998e2e97643af32e388efed87387263 639 SUPERFAMILY SSF52540 5 234 1.0E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2331 2998e2e97643af32e388efed87387263 639 Pfam PF13500 AAA domain 5 227 1.3E-17 T 14-10-2018 Theos_2331 2998e2e97643af32e388efed87387263 639 Gene3D G3DSA:3.40.50.300 4 233 8.5E-47 T 14-10-2018 Theos_2331 2998e2e97643af32e388efed87387263 639 Gene3D G3DSA:3.40.50.300 478 637 7.7E-47 T 14-10-2018 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 Gene3D G3DSA:1.10.8.60 278 348 3.8E-24 T 14-10-2018 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 145 165 1.5E-51 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Theos_0001 758659805d6fb150bec8f21f2bc18224 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 243 270 1.5E-51 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Theos_0001 758659805d6fb150bec8f21f2bc18224 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 1.5E-51 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Theos_0001 758659805d6fb150bec8f21f2bc18224 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 177 191 1.5E-51 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Theos_0001 758659805d6fb150bec8f21f2bc18224 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 209 223 1.5E-51 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Theos_0001 758659805d6fb150bec8f21f2bc18224 446 Gene3D G3DSA:3.30.300.180 10 89 2.6E-16 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily Theos_0001 758659805d6fb150bec8f21f2bc18224 446 Pfam PF11638 DnaA N-terminal domain 15 75 2.2E-18 T 14-10-2018 IPR024633 DnaA N-terminal domain Theos_0001 758659805d6fb150bec8f21f2bc18224 446 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 14 446 33.278 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 SUPERFAMILY SSF52540 111 322 3.54E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0001 758659805d6fb150bec8f21f2bc18224 446 SUPERFAMILY SSF48295 344 445 6.02E-32 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 Gene3D G3DSA:3.40.50.300 100 276 2.8E-54 T 14-10-2018 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 358 424 5.3E-28 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 SMART SM00760 355 424 2.1E-37 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 SMART SM00382 144 272 6.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0001 758659805d6fb150bec8f21f2bc18224 446 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 17 445 6.1E-169 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 14-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 Gene3D G3DSA:1.10.1750.10 349 446 4.7E-32 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Theos_0001 758659805d6fb150bec8f21f2bc18224 446 Pfam PF00308 Bacterial dnaA protein 112 329 1.1E-97 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 PRINTS PR00148 Enolase signature 37 51 1.8E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 PRINTS PR00148 Enolase signature 362 379 1.8E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 PRINTS PR00148 Enolase signature 310 321 1.8E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 PRINTS PR00148 Enolase signature 333 347 1.8E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 PRINTS PR00148 Enolase signature 160 173 1.8E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 PRINTS PR00148 Enolase signature 106 122 1.8E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 419 4.0E-128 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 SMART SM01193 4 133 1.2E-87 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 ProSitePatterns PS00164 Enolase signature. 333 346 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 SUPERFAMILY SSF51604 139 421 8.43E-127 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 Gene3D G3DSA:3.30.390.10 1 126 7.3E-51 T 14-10-2018 IPR029017 Enolase-like, N-terminal Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 PIRSF PIRSF001400 1 422 2.5E-187 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 SUPERFAMILY SSF54826 3 136 4.86E-53 T 14-10-2018 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 Gene3D G3DSA:3.20.20.120 128 422 1.6E-133 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 420 1.4E-202 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 Pfam PF03952 Enolase, N-terminal domain 4 133 1.4E-54 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 SMART SM01192 138 420 8.5E-216 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_0003 8b62cb25d44b40f39a3518697ccac83a 422 Hamap MF_00318 Enolase [eno]. 2 410 45.938 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Theos_1035 d49b27ff786fb08b812a1f4c25154876 164 Gene3D G3DSA:3.40.1050.10 6 146 1.2E-11 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Theos_1035 d49b27ff786fb08b812a1f4c25154876 164 SMART SM00947 18 149 3.1E-7 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Theos_1035 d49b27ff786fb08b812a1f4c25154876 164 SUPERFAMILY SSF53056 20 105 4.84E-12 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Theos_2372 0ef7d5261d871d1d8c607fbded27587f 185 Gene3D G3DSA:1.10.1740.10 8 86 4.8E-26 T 14-10-2018 Theos_2372 0ef7d5261d871d1d8c607fbded27587f 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 181 3.7E-29 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Theos_2372 0ef7d5261d871d1d8c607fbded27587f 185 SUPERFAMILY SSF88946 4 107 5.02E-26 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Theos_2372 0ef7d5261d871d1d8c607fbded27587f 185 Pfam PF04545 Sigma-70, region 4 131 180 3.2E-12 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Theos_2372 0ef7d5261d871d1d8c607fbded27587f 185 Gene3D G3DSA:1.10.10.10 87 184 6.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2372 0ef7d5261d871d1d8c607fbded27587f 185 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 48 80 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Theos_2372 0ef7d5261d871d1d8c607fbded27587f 185 Pfam PF04542 Sigma-70 region 2 26 93 7.2E-19 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Theos_2372 0ef7d5261d871d1d8c607fbded27587f 185 SUPERFAMILY SSF88659 113 184 3.55E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Theos_1689 7f6c26c8cfa052dabafde5b6c0579be3 86 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 22 68 6.3E-12 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 Theos_1689 7f6c26c8cfa052dabafde5b6c0579be3 86 Pfam PF12728 Helix-turn-helix domain 22 68 1.8E-11 T 14-10-2018 Theos_1689 7f6c26c8cfa052dabafde5b6c0579be3 86 Gene3D G3DSA:1.10.1660.10 19 70 1.6E-7 T 14-10-2018 Theos_1689 7f6c26c8cfa052dabafde5b6c0579be3 86 SUPERFAMILY SSF46955 22 68 3.84E-5 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 244 8.8E-60 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 Gene3D G3DSA:3.40.47.10 1 252 6.2E-94 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 SUPERFAMILY SSF53901 212 408 2.37E-77 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 SMART SM00825 Beta-ketoacyl synthase 4 400 1.9E-16 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 Gene3D G3DSA:3.40.47.10 254 398 2.1E-60 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 SUPERFAMILY SSF53901 1 249 8.27E-80 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 PIRSF PIRSF000447 1 409 4.8E-198 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 407 3.0E-193 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 Theos_0669 35b2e6598db55f08242a36aa8baf26e1 409 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 366 3.6E-42 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal Theos_0628 9f833a28fbd4b10fa8b2ced55559200e 176 SUPERFAMILY SSF55729 20 155 1.26E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_0628 9f833a28fbd4b10fa8b2ced55559200e 176 Pfam PF13302 Acetyltransferase (GNAT) domain 20 149 2.5E-22 T 14-10-2018 IPR000182 GNAT domain Theos_0628 9f833a28fbd4b10fa8b2ced55559200e 176 Gene3D G3DSA:3.40.630.30 8 175 1.3E-32 T 14-10-2018 Theos_0970 d59b40c3bd02b30384f79ae417db7e61 246 Gene3D G3DSA:3.90.850.10 41 245 5.2E-74 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Theos_0970 d59b40c3bd02b30384f79ae417db7e61 246 SUPERFAMILY SSF56529 37 244 6.67E-72 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Theos_0970 d59b40c3bd02b30384f79ae417db7e61 246 Gene3D G3DSA:2.30.30.370 1 40 1.3E-22 T 14-10-2018 Theos_0970 d59b40c3bd02b30384f79ae417db7e61 246 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 244 4.2E-113 T 14-10-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 Theos_0970 d59b40c3bd02b30384f79ae417db7e61 246 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 45 243 6.1E-61 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 189 421 2.0E-75 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 SUPERFAMILY SSF53223 13 191 6.72E-69 T 14-10-2018 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 43 171 2.0E-55 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 108 121 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 SMART SM00839 191 421 1.1E-98 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 Gene3D G3DSA:3.40.50.10860 49 188 2.5E-64 T 14-10-2018 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 PIRSF PIRSF000185 17 424 1.7E-162 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 180 202 2.2E-33 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 349 360 2.2E-33 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 100 114 2.2E-33 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 222 242 2.2E-33 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 SUPERFAMILY SSF51735 189 423 3.09E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 Gene3D G3DSA:3.40.50.720 189 424 2.6E-88 T 14-10-2018 Theos_0627 17949ad28a1e9a8cf420134350f388fa 424 Gene3D G3DSA:1.10.8.1210 4 48 1.2E-17 T 14-10-2018 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 14-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 412 3.5E-153 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 99 6.3E-35 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 SMART SM01210 321 412 2.3E-47 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 SUPERFAMILY SSF51246 320 412 3.22E-28 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 Gene3D G3DSA:3.30.1490.20 118 183 2.6E-20 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 Gene3D G3DSA:3.30.470.20 184 320 1.4E-56 T 14-10-2018 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 Gene3D G3DSA:3.40.50.20 1 92 8.7E-37 T 14-10-2018 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 412 41.945 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 SMART SM01209 100 287 4.6E-113 T 14-10-2018 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 100 287 2.0E-69 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 323 410 1.2E-25 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 SUPERFAMILY SSF52440 1 100 4.03E-33 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 SUPERFAMILY SSF56059 101 315 6.36E-58 T 14-10-2018 Theos_0588 92e311d9fb1e5b16eb7200e0ac60c5b3 416 Gene3D G3DSA:3.90.600.10 321 413 3.2E-34 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_1973 3c04274e00475915fa62714ee5232b87 333 Pfam PF02769 AIR synthase related protein, C-terminal domain 172 331 1.4E-22 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Theos_1973 3c04274e00475915fa62714ee5232b87 333 Gene3D G3DSA:3.30.1330.10 1 166 1.5E-54 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Theos_1973 3c04274e00475915fa62714ee5232b87 333 Pfam PF00586 AIR synthase related protein, N-terminal domain 56 160 6.5E-16 T 14-10-2018 IPR016188 PurM-like, N-terminal domain Theos_1973 3c04274e00475915fa62714ee5232b87 333 Gene3D G3DSA:3.90.650.10 167 333 3.2E-64 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Theos_1973 3c04274e00475915fa62714ee5232b87 333 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 1 333 38.608 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_1973 3c04274e00475915fa62714ee5232b87 333 SUPERFAMILY SSF55326 2 165 3.89E-41 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Theos_1973 3c04274e00475915fa62714ee5232b87 333 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 324 1.1E-100 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_1973 3c04274e00475915fa62714ee5232b87 333 SUPERFAMILY SSF56042 168 331 1.13E-49 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Theos_2292 344df1e6a0268528badaa129c0ec993c 431 Pfam PF00083 Sugar (and other) transporter 53 431 7.7E-45 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Theos_2292 344df1e6a0268528badaa129c0ec993c 431 SUPERFAMILY SSF103473 7 431 7.72E-90 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_2292 344df1e6a0268528badaa129c0ec993c 431 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 317 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Theos_2292 344df1e6a0268528badaa129c0ec993c 431 ProSitePatterns PS00216 Sugar transport proteins signature 1. 73 89 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Theos_2292 344df1e6a0268528badaa129c0ec993c 431 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Theos_2463 de929ca7c96275ad5c05cc7ccf273ed8 228 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2463 de929ca7c96275ad5c05cc7ccf273ed8 228 Gene3D G3DSA:3.40.50.300 1 226 4.3E-59 T 14-10-2018 Theos_2463 de929ca7c96275ad5c05cc7ccf273ed8 228 SUPERFAMILY SSF52540 3 221 1.02E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2463 de929ca7c96275ad5c05cc7ccf273ed8 228 SMART SM00382 27 208 1.2E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2463 de929ca7c96275ad5c05cc7ccf273ed8 228 Pfam PF00005 ABC transporter 18 157 5.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1074 38f7a4fd35ad4bd46472e6c50c65a91a 421 Gene3D G3DSA:3.90.1150.10 286 421 8.6E-53 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_1074 38f7a4fd35ad4bd46472e6c50c65a91a 421 PIRSF PIRSF001434 1 421 2.9E-121 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Theos_1074 38f7a4fd35ad4bd46472e6c50c65a91a 421 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 2 420 2.9E-191 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 Theos_1074 38f7a4fd35ad4bd46472e6c50c65a91a 421 Gene3D G3DSA:3.40.640.10 1 285 5.4E-99 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_1074 38f7a4fd35ad4bd46472e6c50c65a91a 421 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 420 1.4E-127 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Theos_1074 38f7a4fd35ad4bd46472e6c50c65a91a 421 SUPERFAMILY SSF53383 1 420 2.13E-122 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_1297 8ccb1c913ebed5df4490fe4abbff158f 350 Pfam PF13407 Periplasmic binding protein domain 29 284 4.9E-61 T 14-10-2018 IPR025997 Periplasmic binding protein Theos_1297 8ccb1c913ebed5df4490fe4abbff158f 350 Gene3D G3DSA:3.40.50.2300 30 312 4.7E-94 T 14-10-2018 Theos_1297 8ccb1c913ebed5df4490fe4abbff158f 350 TIGRFAM TIGR02634 xylF: D-xylose ABC transporter, D-xylose-binding protein 29 336 7.3E-126 T 14-10-2018 IPR013456 D-xylose ABC transporter, substrate-binding protein GO:0015753|GO:0048029 Theos_1297 8ccb1c913ebed5df4490fe4abbff158f 350 Gene3D G3DSA:3.40.50.2300 129 323 4.7E-94 T 14-10-2018 Theos_1297 8ccb1c913ebed5df4490fe4abbff158f 350 SUPERFAMILY SSF53822 26 323 5.03E-70 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_0407 68ff72d29dc735c1f2d587a3497ff770 142 Pfam PF02566 OsmC-like protein 40 131 3.5E-17 T 14-10-2018 IPR003718 OsmC/Ohr family Theos_0407 68ff72d29dc735c1f2d587a3497ff770 142 SUPERFAMILY SSF82784 3 139 2.09E-37 T 14-10-2018 IPR036102 OsmC/Ohr superfamily Theos_0407 68ff72d29dc735c1f2d587a3497ff770 142 Gene3D G3DSA:3.30.300.20 1 142 3.3E-43 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_0407 68ff72d29dc735c1f2d587a3497ff770 142 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 138 2.6E-53 T 14-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 Theos_1144 d771c992cd48c28601192206b30453b3 278 Gene3D G3DSA:1.10.1240.10 81 159 1.0E-25 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1144 d771c992cd48c28601192206b30453b3 278 Gene3D G3DSA:1.10.1660.10 1 77 5.1E-32 T 14-10-2018 Theos_1144 d771c992cd48c28601192206b30453b3 278 SUPERFAMILY SSF46955 7 91 1.47E-16 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_1144 d771c992cd48c28601192206b30453b3 278 SUPERFAMILY SSF52242 162 266 5.89E-11 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Theos_1144 d771c992cd48c28601192206b30453b3 278 Pfam PF02607 B12 binding domain 84 155 1.0E-10 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1144 d771c992cd48c28601192206b30453b3 278 SMART SM00422 7 77 3.6E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Theos_1144 d771c992cd48c28601192206b30453b3 278 Gene3D G3DSA:3.40.50.280 160 277 1.6E-30 T 14-10-2018 Theos_1144 d771c992cd48c28601192206b30453b3 278 Pfam PF13411 MerR HTH family regulatory protein 7 74 3.9E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Theos_1680 97ebe6c09d23d8391bc2f52c3ee3376f 202 SUPERFAMILY SSF52540 1 198 9.67E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1680 97ebe6c09d23d8391bc2f52c3ee3376f 202 ProSitePatterns PS01331 Thymidylate kinase signature. 88 100 - T 14-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Theos_1680 97ebe6c09d23d8391bc2f52c3ee3376f 202 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 189 4.2E-49 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Theos_1680 97ebe6c09d23d8391bc2f52c3ee3376f 202 Hamap MF_00165 Thymidylate kinase [tmk]. 4 197 30.171 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Theos_1680 97ebe6c09d23d8391bc2f52c3ee3376f 202 Pfam PF02223 Thymidylate kinase 8 189 3.6E-48 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 Theos_1680 97ebe6c09d23d8391bc2f52c3ee3376f 202 Gene3D G3DSA:3.40.50.300 1 197 2.6E-65 T 14-10-2018 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 140 153 1.3E-52 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 520 540 1.3E-52 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 239 254 1.3E-52 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 694 720 1.3E-52 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 562 591 1.3E-52 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 181 197 1.3E-52 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 367 387 1.3E-52 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 522 534 - T 14-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 Pfam PF00311 Phosphoenolpyruvate carboxylase 329 858 7.5E-153 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 Pfam PF00311 Phosphoenolpyruvate carboxylase 136 323 7.9E-43 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 141 152 - T 14-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 2 858 16.612 T 14-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Theos_0883 cbcc6db188c05805ffe75742d9382d3f 858 SUPERFAMILY SSF51621 11 858 6.59E-238 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Theos_1719 066614c965a7e6703922d646d55d154d 168 Gene3D G3DSA:3.40.50.880 2 164 2.1E-14 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1719 066614c965a7e6703922d646d55d154d 168 SUPERFAMILY SSF52317 3 152 9.67E-13 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1367 89baee4724723852aad75cdfbffff24d 301 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 195 216 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 Theos_1367 89baee4724723852aad75cdfbffff24d 301 Pfam PF13624 SurA N-terminal domain 8 137 6.7E-8 T 14-10-2018 Theos_1367 89baee4724723852aad75cdfbffff24d 301 SUPERFAMILY SSF109998 19 196 3.57E-20 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily Theos_1367 89baee4724723852aad75cdfbffff24d 301 Pfam PF00639 PPIC-type PPIASE domain 179 255 2.7E-19 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Theos_1367 89baee4724723852aad75cdfbffff24d 301 Gene3D G3DSA:1.10.4030.30 19 260 1.2E-37 T 14-10-2018 Theos_1367 89baee4724723852aad75cdfbffff24d 301 Gene3D G3DSA:3.10.50.40 167 258 1.2E-37 T 14-10-2018 Theos_1367 89baee4724723852aad75cdfbffff24d 301 SUPERFAMILY SSF54534 163 255 1.64E-26 T 14-10-2018 Theos_2180 3f84c62b3349a7155090d898ad22da81 267 Gene3D G3DSA:2.40.30.90 170 257 1.8E-29 T 14-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal Theos_2180 3f84c62b3349a7155090d898ad22da81 267 Gene3D G3DSA:3.40.50.10790 1 169 1.0E-56 T 14-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal Theos_2180 3f84c62b3349a7155090d898ad22da81 267 SUPERFAMILY SSF102522 2 170 9.94E-48 T 14-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal Theos_2180 3f84c62b3349a7155090d898ad22da81 267 PIRSF PIRSF006779 1 259 2.4E-56 T 14-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase Theos_2180 3f84c62b3349a7155090d898ad22da81 267 SUPERFAMILY SSF101852 175 257 2.35E-19 T 14-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal Theos_2180 3f84c62b3349a7155090d898ad22da81 267 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 4 255 5.2E-69 T 14-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase Theos_1014 c7b98533c63974b8a42baaa2b10d734c 109 Gene3D G3DSA:1.10.10.10 3 109 3.1E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1014 c7b98533c63974b8a42baaa2b10d734c 109 SMART SM00418 14 97 0.0015 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_1014 c7b98533c63974b8a42baaa2b10d734c 109 SUPERFAMILY SSF46785 7 106 2.09E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1014 c7b98533c63974b8a42baaa2b10d734c 109 Pfam PF01638 HxlR-like helix-turn-helix 18 105 7.3E-24 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type Theos_0021 11d8a4d0889d5b24fd9125f0594c7deb 139 Gene3D G3DSA:2.60.40.1890 23 138 1.2E-41 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily Theos_0021 11d8a4d0889d5b24fd9125f0594c7deb 139 SUPERFAMILY SSF110087 4 137 5.36E-44 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily Theos_0021 11d8a4d0889d5b24fd9125f0594c7deb 139 Pfam PF04314 Copper chaperone PCu(A)C 23 132 1.3E-36 T 14-10-2018 IPR007410 Copper chaperone PCuAC Theos_2297 15697619f56742adfb7bcd16a4706779 206 Pfam PF02581 Thiamine monophosphate synthase 5 185 2.8E-56 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Theos_2297 15697619f56742adfb7bcd16a4706779 206 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 4 197 3.1E-59 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Theos_2297 15697619f56742adfb7bcd16a4706779 206 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 3 203 25.7 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Theos_2297 15697619f56742adfb7bcd16a4706779 206 Gene3D G3DSA:3.20.20.70 2 203 2.4E-66 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_2297 15697619f56742adfb7bcd16a4706779 206 SUPERFAMILY SSF51391 4 200 1.96E-63 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Theos_1772 4257179c8b60731d4b90d1e6e643aa67 642 SUPERFAMILY SSF56801 8 607 1.06E-115 T 14-10-2018 Theos_1772 4257179c8b60731d4b90d1e6e643aa67 642 Pfam PF00501 AMP-binding enzyme 22 476 1.0E-88 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_1772 4257179c8b60731d4b90d1e6e643aa67 642 Gene3D G3DSA:3.40.50.12780 7 305 2.0E-49 T 14-10-2018 Theos_1772 4257179c8b60731d4b90d1e6e643aa67 642 Gene3D G3DSA:3.40.50.12780 326 469 2.1E-36 T 14-10-2018 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 301 354 5.6E-10 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 62 287 3.1E-28 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Pfam PF00391 PEP-utilising enzyme, mobile domain 420 499 5.2E-25 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Gene3D G3DSA:3.20.20.60 528 853 1.3E-134 T 14-10-2018 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Gene3D G3DSA:1.10.189.10 343 525 9.3E-64 T 14-10-2018 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Gene3D G3DSA:3.50.30.10 381 505 9.3E-64 T 14-10-2018 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 517 852 1.4E-83 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 SUPERFAMILY SSF56059 4 377 1.09E-124 T 14-10-2018 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Gene3D G3DSA:3.30.1490.20 15 241 1.5E-87 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Gene3D G3DSA:1.20.80.30 110 196 1.5E-87 T 14-10-2018 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 853 0.0 T 14-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 745 763 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 SUPERFAMILY SSF52009 383 508 1.29E-34 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 Gene3D G3DSA:3.30.470.20 242 339 2.8E-39 T 14-10-2018 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 PIRSF PIRSF000853 1 859 0.0 T 14-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 446 457 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Theos_0160 5117a667c826a9ee1b6172f2215d7265 864 SUPERFAMILY SSF51621 517 856 9.42E-111 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Theos_0650 e3c91f3df6b953cf631d95a32ac84876 126 Gene3D G3DSA:3.10.180.10 4 126 1.5E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_0650 e3c91f3df6b953cf631d95a32ac84876 126 SUPERFAMILY SSF54593 7 119 3.03E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_0650 e3c91f3df6b953cf631d95a32ac84876 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 1.8E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Theos_0702 c1200301b6842e9701d59d28f566dd91 443 Gene3D G3DSA:3.40.50.300 164 443 8.2E-111 T 14-10-2018 Theos_0702 c1200301b6842e9701d59d28f566dd91 443 SUPERFAMILY SSF48024 4 116 2.22E-35 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 Theos_0702 c1200301b6842e9701d59d28f566dd91 443 Pfam PF00772 DnaB-like helicase N terminal domain 6 108 1.3E-34 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 Theos_0702 c1200301b6842e9701d59d28f566dd91 443 Pfam PF03796 DnaB-like helicase C terminal domain 182 439 3.3E-110 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 Theos_0702 c1200301b6842e9701d59d28f566dd91 443 SUPERFAMILY SSF52540 180 432 3.72E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0702 c1200301b6842e9701d59d28f566dd91 443 Gene3D G3DSA:1.10.860.10 1 149 6.5E-59 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal Theos_0702 c1200301b6842e9701d59d28f566dd91 443 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 6 441 4.4E-171 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 Theos_0083 33772c7c980118ac3955aad17743ec56 236 Gene3D G3DSA:3.40.50.1820 2 235 4.4E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_0083 33772c7c980118ac3955aad17743ec56 236 SUPERFAMILY SSF53474 4 233 3.41E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_0083 33772c7c980118ac3955aad17743ec56 236 Pfam PF12697 Alpha/beta hydrolase family 4 224 8.5E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 Gene3D G3DSA:3.40.47.10 6 278 2.2E-155 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 Pfam PF00108 Thiolase, N-terminal domain 5 265 1.9E-75 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 PIRSF PIRSF000429 1 396 4.1E-140 T 14-10-2018 IPR002155 Thiolase GO:0016747 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 Pfam PF02803 Thiolase, C-terminal domain 272 393 7.4E-48 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 SUPERFAMILY SSF53901 3 272 6.51E-79 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 SUPERFAMILY SSF53901 273 394 7.2E-45 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 Gene3D G3DSA:3.40.47.10 129 391 2.2E-155 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1530 6433c944ae91af65e341bfd3ce6ab603 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 393 9.7E-147 T 14-10-2018 IPR002155 Thiolase GO:0016747 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 Gene3D G3DSA:1.25.40.80 120 257 6.9E-29 T 14-10-2018 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 Gene3D G3DSA:3.40.50.620 1 119 2.7E-40 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 Pfam PF00875 DNA photolyase 3 152 7.7E-32 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 289 301 - T 14-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 PRINTS PR00147 DNA photolyase signature 289 305 2.1E-19 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 PRINTS PR00147 DNA photolyase signature 309 327 2.1E-19 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 PRINTS PR00147 DNA photolyase signature 127 143 2.1E-19 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 PRINTS PR00147 DNA photolyase signature 348 362 2.1E-19 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 SUPERFAMILY SSF48173 163 412 4.58E-83 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 SUPERFAMILY SSF52425 2 161 7.46E-39 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 Pfam PF03441 FAD binding domain of DNA photolyase 240 394 6.8E-57 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 Theos_1146 69d9ef59051907bc43f7b775304a0d29 417 Gene3D G3DSA:1.10.579.10 258 416 1.5E-59 T 14-10-2018 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 SUPERFAMILY SSF54292 1 95 8.13E-21 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 141 1.1E-14 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 SUPERFAMILY SSF50692 685 764 4.97E-25 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Gene3D G3DSA:3.30.70.20 160 237 1.5E-7 T 14-10-2018 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 643 1.9E-144 T 14-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 SUPERFAMILY SSF54862 97 244 7.95E-32 T 14-10-2018 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Gene3D G3DSA:3.40.50.740 573 669 3.3E-7 T 14-10-2018 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 SMART SM00926 249 303 4.5E-12 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Gene3D G3DSA:3.10.20.740 1 144 1.6E-28 T 14-10-2018 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Pfam PF00384 Molybdopterin oxidoreductase 305 374 2.7E-10 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 180 190 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Gene3D G3DSA:2.40.40.20 670 770 2.2E-7 T 14-10-2018 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 SUPERFAMILY SSF53706 247 655 1.57E-79 T 14-10-2018 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 95 1.5E-12 T 14-10-2018 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Gene3D G3DSA:3.40.50.740 305 380 7.2E-8 T 14-10-2018 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 SMART SM00929 104 144 2.7E-16 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 119 131 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Pfam PF01568 Molydopterin dinucleotide binding domain 703 758 1.0E-8 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 249 299 9.6E-9 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0710 a51e413fc6fa239aef6c401d2e8b1e94 780 Gene3D G3DSA:2.20.25.90 249 303 2.3E-14 T 14-10-2018 Theos_1768 d61c342e4e1e407dceddf13b5b6c6e40 273 Pfam PF00005 ABC transporter 30 178 9.2E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1768 d61c342e4e1e407dceddf13b5b6c6e40 273 SMART SM00382 39 235 1.9E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1768 d61c342e4e1e407dceddf13b5b6c6e40 273 SUPERFAMILY SSF52540 13 250 1.3E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1768 d61c342e4e1e407dceddf13b5b6c6e40 273 Gene3D G3DSA:3.40.50.300 11 252 6.1E-55 T 14-10-2018 Theos_1768 d61c342e4e1e407dceddf13b5b6c6e40 273 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0761 fd65234f3d6d270c1e16b3b9d4892285 393 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 319 325 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Theos_0761 fd65234f3d6d270c1e16b3b9d4892285 393 SUPERFAMILY SSF53335 34 163 6.15E-9 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0761 fd65234f3d6d270c1e16b3b9d4892285 393 SUPERFAMILY SSF53335 208 376 9.33E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0761 fd65234f3d6d270c1e16b3b9d4892285 393 Pfam PF05175 Methyltransferase small domain 215 385 1.1E-41 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Theos_0761 fd65234f3d6d270c1e16b3b9d4892285 393 Gene3D G3DSA:3.40.50.150 197 392 6.3E-53 T 14-10-2018 Theos_0761 fd65234f3d6d270c1e16b3b9d4892285 393 Gene3D G3DSA:3.40.50.150 17 195 5.2E-40 T 14-10-2018 Theos_1967 06ffd4ef702d552bcb446061a5e387de 134 PIRSF PIRSF030042 1 134 4.5E-49 T 14-10-2018 IPR016942 Uncharacterised conserved protein UCP030042 Theos_1967 06ffd4ef702d552bcb446061a5e387de 134 Pfam PF14340 Domain of unknown function (DUF4395) 4 125 8.0E-32 T 14-10-2018 IPR025508 Domain of unknown function DUF4395 Theos_1710 fd5ae6e889f91a33b4e64754f05a1865 134 Gene3D G3DSA:3.10.129.10 1 134 3.7E-51 T 14-10-2018 Theos_1710 fd5ae6e889f91a33b4e64754f05a1865 134 SUPERFAMILY SSF54637 4 129 2.42E-31 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_1710 fd5ae6e889f91a33b4e64754f05a1865 134 Pfam PF03061 Thioesterase superfamily 42 119 9.0E-16 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Theos_1710 fd5ae6e889f91a33b4e64754f05a1865 134 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 14 127 1.9E-35 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 Gene3D G3DSA:3.40.1110.10 479 593 4.2E-82 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 Pfam PF00702 haloacid dehalogenase-like hydrolase 465 675 3.7E-49 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 Pfam PF00122 E1-E2 ATPase 269 447 6.5E-55 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 182 770 1.3E-173 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 236 769 9.6E-117 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 SUPERFAMILY SSF55008 60 125 4.71E-21 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 61 123 1.5E-13 T 14-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 ProSitePatterns PS01047 Heavy-metal-associated domain. 65 94 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 Gene3D G3DSA:2.70.150.20 261 373 2.4E-39 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 240 738 2.1E-89 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 Gene3D G3DSA:3.30.70.100 1 57 5.5E-14 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00943 Copper-transporting ATPase signature 391 405 1.2E-9 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00943 Copper-transporting ATPase signature 104 124 1.2E-9 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00943 Copper-transporting ATPase signature 238 257 1.2E-9 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00943 Copper-transporting ATPase signature 258 276 1.2E-9 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00943 Copper-transporting ATPase signature 638 655 1.2E-9 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 SUPERFAMILY SSF81665 235 737 2.75E-13 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 468 482 1.0E-28 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 318 332 1.0E-28 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 586 597 1.0E-28 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 608 618 1.0E-28 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 661 680 1.0E-28 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 684 696 1.0E-28 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 ProSitePatterns PS01229 Hypothetical cof family signature 2. 661 683 - T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 Pfam PF00403 Heavy-metal-associated domain 63 123 4.3E-16 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 Pfam PF00403 Heavy-metal-associated domain 1 55 5.4E-8 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 201 769 3.2E-178 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 Gene3D G3DSA:3.40.50.1000 449 712 4.2E-82 T 14-10-2018 IPR023214 HAD superfamily Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 SUPERFAMILY SSF56784 468 767 3.12E-52 T 14-10-2018 IPR036412 HAD-like superfamily Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 SUPERFAMILY SSF81653 271 368 9.68E-29 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 Gene3D G3DSA:3.30.70.100 58 124 2.2E-22 T 14-10-2018 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 SUPERFAMILY SSF55008 1 57 5.89E-14 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Theos_0100 8be7cccb7666ebb010559f99ea64a9ad 781 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 470 476 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Theos_2452 80a99c761473ca6e45011d815d31ea67 219 PIRSF PIRSF000709 1 175 1.1E-6 T 14-10-2018 Theos_2452 80a99c761473ca6e45011d815d31ea67 219 SUPERFAMILY SSF53254 1 183 2.16E-38 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_2452 80a99c761473ca6e45011d815d31ea67 219 Gene3D G3DSA:3.40.50.1240 1 180 2.8E-33 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_2452 80a99c761473ca6e45011d815d31ea67 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 180 1.7E-36 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Theos_2452 80a99c761473ca6e45011d815d31ea67 219 SMART SM00855 4 152 2.4E-14 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 SUPERFAMILY SSF47203 228 379 1.8E-62 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 Gene3D G3DSA:1.20.140.10 236 381 9.8E-61 T 14-10-2018 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 PIRSF PIRSF016578 131 380 2.8E-16 T 14-10-2018 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 PIRSF PIRSF016578 5 86 3.3E-4 T 14-10-2018 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 Gene3D G3DSA:2.40.110.10 122 235 4.1E-42 T 14-10-2018 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 116 2.4E-30 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 379 8.5E-55 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 SUPERFAMILY SSF56645 3 241 6.28E-82 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 Gene3D G3DSA:1.10.540.10 1 121 1.2E-40 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Theos_1509 747d515ebeba9f3c6a5ff79b02abffd6 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 2.7E-26 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Theos_0609 661cb139395ace30902cc5c02f53c043 340 SUPERFAMILY SSF55729 9 149 1.27E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_0609 661cb139395ace30902cc5c02f53c043 340 SUPERFAMILY SSF55729 140 316 2.93E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_0609 661cb139395ace30902cc5c02f53c043 340 Gene3D G3DSA:3.40.630.30 120 303 1.5E-42 T 14-10-2018 Theos_0609 661cb139395ace30902cc5c02f53c043 340 Gene3D G3DSA:3.40.630.30 1 94 9.6E-16 T 14-10-2018 Theos_0609 661cb139395ace30902cc5c02f53c043 340 Pfam PF02388 FemAB family 127 206 4.1E-6 T 14-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 Theos_0609 661cb139395ace30902cc5c02f53c043 340 Pfam PF02388 FemAB family 9 80 5.5E-7 T 14-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 Theos_0609 661cb139395ace30902cc5c02f53c043 340 Pfam PF02388 FemAB family 217 302 1.4E-15 T 14-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 Theos_1543 a1ab938356e50478aae402f7f9c0302d 278 Gene3D G3DSA:3.40.50.10170 3 150 2.3E-41 T 14-10-2018 Theos_1543 a1ab938356e50478aae402f7f9c0302d 278 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 275 1.6E-61 T 14-10-2018 IPR003797 DegV Theos_1543 a1ab938356e50478aae402f7f9c0302d 278 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 274 1.1E-64 T 14-10-2018 IPR003797 DegV Theos_1543 a1ab938356e50478aae402f7f9c0302d 278 SUPERFAMILY SSF82549 3 275 8.37E-59 T 14-10-2018 Theos_1543 a1ab938356e50478aae402f7f9c0302d 278 Gene3D G3DSA:3.30.1180.10 152 276 5.7E-17 T 14-10-2018 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 188 201 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 613 36.754 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 Gene3D G3DSA:3.30.420.40 5 370 6.0E-155 T 14-10-2018 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 SUPERFAMILY SSF100920 378 534 7.46E-62 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 591 5.5E-281 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 SUPERFAMILY SSF53067 183 376 1.54E-66 T 14-10-2018 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 PRINTS PR00301 70kDa heat shock protein signature 31 43 9.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 PRINTS PR00301 70kDa heat shock protein signature 328 344 9.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 PRINTS PR00301 70kDa heat shock protein signature 359 379 9.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 PRINTS PR00301 70kDa heat shock protein signature 53 61 9.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 PRINTS PR00301 70kDa heat shock protein signature 135 155 9.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 PRINTS PR00301 70kDa heat shock protein signature 382 401 9.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 PRINTS PR00301 70kDa heat shock protein signature 3 16 9.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 PRINTS PR00301 70kDa heat shock protein signature 463 479 9.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 PRINTS PR00301 70kDa heat shock protein signature 194 204 9.7E-75 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 Gene3D G3DSA:3.90.640.10 221 310 6.0E-155 T 14-10-2018 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 Pfam PF00012 Hsp70 protein 4 590 5.7E-245 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 SUPERFAMILY SSF53067 2 180 5.18E-63 T 14-10-2018 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 331 345 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 Gene3D G3DSA:3.30.420.40 177 360 6.0E-155 T 14-10-2018 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 Gene3D G3DSA:2.60.34.10 371 555 6.5E-78 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Theos_0682 322191f29e77b9d2b80fdc9ef8ba05e8 614 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 Gene3D G3DSA:1.10.287.470 184 238 1.0E-30 T 14-10-2018 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 Gene3D G3DSA:2.40.30.170 278 348 1.0E-30 T 14-10-2018 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 Gene3D G3DSA:2.40.420.20 349 418 1.0E-30 T 14-10-2018 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 Gene3D G3DSA:2.40.50.100 83 116 2.3E-7 T 14-10-2018 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 Pfam PF02321 Outer membrane efflux protein 120 212 8.4E-6 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 Gene3D G3DSA:2.40.50.100 240 277 1.0E-30 T 14-10-2018 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 Pfam PF13437 HlyD family secretion protein 244 351 4.7E-7 T 14-10-2018 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 SUPERFAMILY SSF111369 78 173 2.62E-8 T 14-10-2018 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 Gene3D G3DSA:1.10.287.470 117 146 2.3E-7 T 14-10-2018 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 SUPERFAMILY SSF111369 183 322 7.32E-9 T 14-10-2018 Theos_2438 e322da2d3735ebabb6be8d80322d35ee 434 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 217 420 4.6E-29 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Theos_0716 d514e12c21c76845b575c9a870343e86 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 3 119 18.257 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 Theos_0716 d514e12c21c76845b575c9a870343e86 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 23 118 2.6E-31 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0716 d514e12c21c76845b575c9a870343e86 119 Gene3D G3DSA:1.20.58.1610 1 119 6.9E-43 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0708 a82237d280a67ec5737a33098caa716f 182 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_0708 a82237d280a67ec5737a33098caa716f 182 SUPERFAMILY SSF54862 26 169 1.46E-29 T 14-10-2018 Theos_0708 a82237d280a67ec5737a33098caa716f 182 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 9 136 2.7E-51 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0708 a82237d280a67ec5737a33098caa716f 182 Gene3D G3DSA:3.30.70.3270 26 182 7.8E-66 T 14-10-2018 Theos_0708 a82237d280a67ec5737a33098caa716f 182 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 140 28.098 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0708 a82237d280a67ec5737a33098caa716f 182 Pfam PF12838 4Fe-4S dicluster domain 52 112 4.0E-14 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 14-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 TIGRFAM TIGR00038 efp: translation elongation factor P 2 184 4.8E-69 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 SMART SM00841 128 183 9.1E-34 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 Gene3D G3DSA:2.40.50.140 127 184 9.5E-29 T 14-10-2018 Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 SUPERFAMILY SSF50104 1 62 2.65E-16 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 Gene3D G3DSA:2.30.30.30 1 63 2.1E-27 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 PIRSF PIRSF005901 1 184 1.5E-68 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 3.5E-18 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 SUPERFAMILY SSF50249 128 184 7.88E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 Gene3D G3DSA:2.40.50.140 64 126 8.1E-25 T 14-10-2018 Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 60 7.1E-19 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 Hamap MF_00141 Elongation factor P [efp]. 1 184 44.677 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 Pfam PF09285 Elongation factor P, C-terminal 128 183 4.3E-27 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 SUPERFAMILY SSF50249 65 125 1.67E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1489 f8eeb699fa8d50aa5e580e4f7403439a 184 SMART SM01185 67 120 3.3E-21 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 Theos_1270 1ae5f1099714a096b4a2c0031933e33d 627 Gene3D G3DSA:3.40.50.12780 58 511 1.5E-103 T 14-10-2018 Theos_1270 1ae5f1099714a096b4a2c0031933e33d 627 Pfam PF00501 AMP-binding enzyme 84 517 2.4E-88 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_1270 1ae5f1099714a096b4a2c0031933e33d 627 SUPERFAMILY SSF56801 29 616 2.09E-168 T 14-10-2018 Theos_1270 1ae5f1099714a096b4a2c0031933e33d 627 ProSitePatterns PS00455 Putative AMP-binding domain signature. 255 266 - T 14-10-2018 IPR020845 AMP-binding, conserved site Theos_1270 1ae5f1099714a096b4a2c0031933e33d 627 Pfam PF13193 AMP-binding enzyme C-terminal domain 527 604 1.9E-31 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Theos_1270 1ae5f1099714a096b4a2c0031933e33d 627 Gene3D G3DSA:3.30.300.30 513 626 1.8E-31 T 14-10-2018 Theos_1270 1ae5f1099714a096b4a2c0031933e33d 627 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 81 4.2E-18 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Theos_0977 17fbebec1b4a24b76ea972a2885629c7 580 SUPERFAMILY SSF52540 331 576 5.93E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0977 17fbebec1b4a24b76ea972a2885629c7 580 Pfam PF00005 ABC transporter 349 504 5.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0977 17fbebec1b4a24b76ea972a2885629c7 580 Gene3D G3DSA:3.40.50.300 327 577 1.5E-59 T 14-10-2018 Theos_0977 17fbebec1b4a24b76ea972a2885629c7 580 Pfam PF02653 Branched-chain amino acid transport system / permease component 20 290 6.6E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_0977 17fbebec1b4a24b76ea972a2885629c7 580 SMART SM00382 356 554 2.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0977 17fbebec1b4a24b76ea972a2885629c7 580 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 554 576 3.7E-10 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Theos_1143 58e131028fac34185340f3dc26b03ee7 195 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 154 169 4.4E-5 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_1143 58e131028fac34185340f3dc26b03ee7 195 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 138 154 4.4E-5 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_1143 58e131028fac34185340f3dc26b03ee7 195 SUPERFAMILY SSF51206 2 82 2.09E-19 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Theos_1143 58e131028fac34185340f3dc26b03ee7 195 SMART SM00100 2 101 3.2E-6 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_1143 58e131028fac34185340f3dc26b03ee7 195 Pfam PF00027 Cyclic nucleotide-binding domain 2 78 3.6E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_1143 58e131028fac34185340f3dc26b03ee7 195 Gene3D G3DSA:1.10.10.10 111 195 9.7E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1143 58e131028fac34185340f3dc26b03ee7 195 SUPERFAMILY SSF46785 112 189 1.12E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1143 58e131028fac34185340f3dc26b03ee7 195 SMART SM00419 132 180 9.5E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_1143 58e131028fac34185340f3dc26b03ee7 195 Pfam PF13545 Crp-like helix-turn-helix domain 114 187 6.4E-17 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_1143 58e131028fac34185340f3dc26b03ee7 195 Gene3D G3DSA:2.60.120.10 1 110 1.8E-23 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_2347 c84b93e30d966939fec8c86f3db29ba4 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 294 1.8E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2347 c84b93e30d966939fec8c86f3db29ba4 302 Gene3D G3DSA:1.10.3720.10 59 299 4.0E-62 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2347 c84b93e30d966939fec8c86f3db29ba4 302 SUPERFAMILY SSF161098 63 288 1.13E-54 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1040 c32f96291070354c90243510546a1d99 511 Gene3D G3DSA:1.10.3650.10 381 454 5.6E-16 T 14-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Theos_1040 c32f96291070354c90243510546a1d99 511 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 502 1.0E-192 T 14-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Theos_1040 c32f96291070354c90243510546a1d99 511 Gene3D G3DSA:3.30.70.20 1 296 2.4E-93 T 14-10-2018 Theos_1040 c32f96291070354c90243510546a1d99 511 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 391 455 3.9E-18 T 14-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Theos_1040 c32f96291070354c90243510546a1d99 511 SUPERFAMILY SSF54862 1 488 2.2E-138 T 14-10-2018 Theos_1040 c32f96291070354c90243510546a1d99 511 Pfam PF13247 4Fe-4S dicluster domain 176 272 2.6E-36 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1666 83ed7f188b60e928ed67cc8643472923 126 Pfam PF07883 Cupin domain 45 112 7.4E-21 T 14-10-2018 IPR013096 Cupin 2, conserved barrel Theos_1666 83ed7f188b60e928ed67cc8643472923 126 Gene3D G3DSA:2.60.120.10 3 118 1.6E-33 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_1666 83ed7f188b60e928ed67cc8643472923 126 SUPERFAMILY SSF51182 12 115 3.67E-29 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Theos_0371 c045091103e9bb2d2415924692a3477b 797 SUPERFAMILY SSF51621 463 793 6.02E-96 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Theos_0371 c045091103e9bb2d2415924692a3477b 797 SUPERFAMILY SSF52009 354 465 1.57E-32 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Theos_0371 c045091103e9bb2d2415924692a3477b 797 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 479 790 1.3E-61 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Theos_0371 c045091103e9bb2d2415924692a3477b 797 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 791 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 Theos_0371 c045091103e9bb2d2415924692a3477b 797 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 416 427 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Theos_0371 c045091103e9bb2d2415924692a3477b 797 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 344 7.4E-107 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Theos_0371 c045091103e9bb2d2415924692a3477b 797 Gene3D G3DSA:3.50.30.10 358 466 3.7E-38 T 14-10-2018 Theos_0371 c045091103e9bb2d2415924692a3477b 797 Pfam PF00391 PEP-utilising enzyme, mobile domain 386 457 4.0E-25 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Theos_0371 c045091103e9bb2d2415924692a3477b 797 Gene3D G3DSA:3.20.20.60 480 791 1.1E-97 T 14-10-2018 Theos_0371 c045091103e9bb2d2415924692a3477b 797 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 696 714 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 Theos_0371 c045091103e9bb2d2415924692a3477b 797 PIRSF PIRSF000854 1 796 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 Theos_0371 c045091103e9bb2d2415924692a3477b 797 Gene3D G3DSA:3.30.1490.20 1 193 3.1E-69 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Theos_0371 c045091103e9bb2d2415924692a3477b 797 SUPERFAMILY SSF56059 2 387 2.71E-101 T 14-10-2018 Theos_0371 c045091103e9bb2d2415924692a3477b 797 Gene3D G3DSA:3.30.470.20 194 357 1.3E-46 T 14-10-2018 Theos_2244 a6de34f096a02898ed5dc26b9b402876 871 SUPERFAMILY SSF48452 765 867 2.31E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2244 a6de34f096a02898ed5dc26b9b402876 871 Gene3D G3DSA:1.25.40.10 749 871 2.0E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2244 a6de34f096a02898ed5dc26b9b402876 871 Gene3D G3DSA:1.25.40.10 336 615 1.1E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2244 a6de34f096a02898ed5dc26b9b402876 871 SMART SM01043 751 870 1.1E-6 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain Theos_2244 a6de34f096a02898ed5dc26b9b402876 871 SUPERFAMILY SSF48452 360 517 2.35E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2244 a6de34f096a02898ed5dc26b9b402876 871 SUPERFAMILY SSF46894 681 738 1.39E-5 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Theos_2244 a6de34f096a02898ed5dc26b9b402876 871 Gene3D G3DSA:1.10.10.10 659 748 2.1E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2244 a6de34f096a02898ed5dc26b9b402876 871 Pfam PF03704 Bacterial transcriptional activator domain 767 868 2.2E-5 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain Theos_2548 9721cf016f11520240f1a4a5a6fff661 295 SUPERFAMILY SSF110849 26 148 7.5E-28 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Theos_2548 9721cf016f11520240f1a4a5a6fff661 295 Gene3D G3DSA:1.10.10.2830 100 167 4.1E-9 T 14-10-2018 Theos_2548 9721cf016f11520240f1a4a5a6fff661 295 Gene3D G3DSA:1.10.10.2830 168 247 3.4E-6 T 14-10-2018 Theos_2548 9721cf016f11520240f1a4a5a6fff661 295 SUPERFAMILY SSF109709 107 246 1.83E-16 T 14-10-2018 Theos_2548 9721cf016f11520240f1a4a5a6fff661 295 Pfam PF02195 ParB-like nuclease domain 29 112 8.8E-22 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Theos_2548 9721cf016f11520240f1a4a5a6fff661 295 SMART SM00470 26 113 1.1E-30 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Theos_2548 9721cf016f11520240f1a4a5a6fff661 295 Gene3D G3DSA:3.90.1530.30 38 99 5.2E-24 T 14-10-2018 Theos_2548 9721cf016f11520240f1a4a5a6fff661 295 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 38 142 1.6E-29 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 Hamap MF_02083 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase [lysY]. 1 339 49.411 T 14-10-2018 IPR037535 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase GO:0016620 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 333 36.946 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 SMART SM00859 1 135 9.4E-44 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 SUPERFAMILY SSF51735 1 168 4.41E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1932 f482b5e43bc68b8459718525216f06b7 339 SUPERFAMILY SSF55347 143 307 4.19E-39 T 14-10-2018 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 1 134 1.0E-26 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 152 310 9.0E-10 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 138 154 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 339 1.9E-111 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 Gene3D G3DSA:3.40.50.720 2 325 3.2E-113 T 14-10-2018 Theos_1932 f482b5e43bc68b8459718525216f06b7 339 Gene3D G3DSA:3.30.360.10 141 311 3.2E-113 T 14-10-2018 Theos_2365 3b623834539a81c653148ed931a41afc 446 SUPERFAMILY SSF55874 287 432 7.86E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_2365 3b623834539a81c653148ed931a41afc 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 222 285 2.5E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_2365 3b623834539a81c653148ed931a41afc 446 SMART SM00304 166 220 2.2E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Theos_2365 3b623834539a81c653148ed931a41afc 446 Gene3D G3DSA:3.30.565.10 287 436 2.4E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_2365 3b623834539a81c653148ed931a41afc 446 SUPERFAMILY SSF47384 205 286 2.35E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_2365 3b623834539a81c653148ed931a41afc 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 428 3.0E-12 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_2365 3b623834539a81c653148ed931a41afc 446 Gene3D G3DSA:1.10.287.130 170 285 1.4E-18 T 14-10-2018 Theos_2365 3b623834539a81c653148ed931a41afc 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 374 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_2365 3b623834539a81c653148ed931a41afc 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 427 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_2365 3b623834539a81c653148ed931a41afc 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 408 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_2365 3b623834539a81c653148ed931a41afc 446 SMART SM00387 325 430 4.0E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_2365 3b623834539a81c653148ed931a41afc 446 SMART SM00388 221 285 4.7E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_2365 3b623834539a81c653148ed931a41afc 446 Pfam PF00672 HAMP domain 168 215 8.4E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Theos_2232 dbc693d9e99f64ccd2ded362ea8d36e5 401 Pfam PF13458 Periplasmic binding protein 31 377 3.0E-49 T 14-10-2018 IPR028081 Leucine-binding protein domain Theos_2232 dbc693d9e99f64ccd2ded362ea8d36e5 401 SUPERFAMILY SSF53822 31 395 2.78E-63 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_2232 dbc693d9e99f64ccd2ded362ea8d36e5 401 Gene3D G3DSA:3.40.50.2300 157 290 4.0E-60 T 14-10-2018 Theos_2232 dbc693d9e99f64ccd2ded362ea8d36e5 401 Gene3D G3DSA:3.40.50.2300 32 358 4.0E-60 T 14-10-2018 Theos_1008 8f607e749a28699c5002761aaa11958a 655 Gene3D G3DSA:3.40.30.10 1 167 2.0E-67 T 14-10-2018 Theos_1008 8f607e749a28699c5002761aaa11958a 655 PIRSF PIRSF006402 1 582 5.2E-191 T 14-10-2018 IPR024705 Spermatogenesis-associated protein 20 Theos_1008 8f607e749a28699c5002761aaa11958a 655 SUPERFAMILY SSF48208 184 496 2.66E-55 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Theos_1008 8f607e749a28699c5002761aaa11958a 655 Pfam PF03190 Protein of unknown function, DUF255 2 162 1.1E-72 T 14-10-2018 IPR004879 Domain of unknown function DUF255 Theos_1008 8f607e749a28699c5002761aaa11958a 655 SUPERFAMILY SSF52833 3 126 2.78E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0618 ffa797fd29b6c8c36484e71f6e1c94d6 259 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 13 259 35.092 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Theos_0618 ffa797fd29b6c8c36484e71f6e1c94d6 259 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 46 59 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Theos_0618 ffa797fd29b6c8c36484e71f6e1c94d6 259 Gene3D G3DSA:3.20.20.70 1 258 8.2E-98 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0618 ffa797fd29b6c8c36484e71f6e1c94d6 259 SUPERFAMILY SSF51366 4 239 7.85E-77 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Theos_0618 ffa797fd29b6c8c36484e71f6e1c94d6 259 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 7 239 9.3E-72 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Theos_0618 ffa797fd29b6c8c36484e71f6e1c94d6 259 Pfam PF00290 Tryptophan synthase alpha chain 7 238 1.5E-90 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Theos_1826 896d008c50144e0b9872611ef83f4b7e 528 SUPERFAMILY SSF51445 2 456 2.47E-149 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily Theos_1826 896d008c50144e0b9872611ef83f4b7e 528 Gene3D G3DSA:3.20.20.80 2 451 1.5E-180 T 14-10-2018 Theos_1826 896d008c50144e0b9872611ef83f4b7e 528 Pfam PF00128 Alpha amylase, catalytic domain 25 368 1.2E-98 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Theos_1826 896d008c50144e0b9872611ef83f4b7e 528 SMART SM00642 10 398 1.1E-144 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Theos_1826 896d008c50144e0b9872611ef83f4b7e 528 Gene3D G3DSA:2.60.40.1180 463 528 9.9E-7 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta Theos_1826 896d008c50144e0b9872611ef83f4b7e 528 Gene3D G3DSA:3.90.400.10 102 172 1.5E-180 T 14-10-2018 Theos_1826 896d008c50144e0b9872611ef83f4b7e 528 SUPERFAMILY SSF51011 458 527 4.56E-7 T 14-10-2018 Theos_0631 af14386d0fb11943fe53b850144c10ec 340 SUPERFAMILY SSF52467 2 328 2.48E-100 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Theos_0631 af14386d0fb11943fe53b850144c10ec 340 Gene3D G3DSA:3.40.910.10 3 327 3.9E-92 T 14-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 Theos_0631 af14386d0fb11943fe53b850144c10ec 340 Pfam PF01916 Deoxyhypusine synthase 24 317 1.2E-93 T 14-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 Theos_0631 af14386d0fb11943fe53b850144c10ec 340 Hamap MF_00640 Deoxyhypusine synthase-like protein. 3 340 46.297 T 14-10-2018 IPR023496 Deoxyhypusine synthase-like GO:0016765 Theos_0819 9b75140cca47257116498f0384fbf10a 323 SUPERFAMILY SSF103486 5 321 1.44E-69 T 14-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0819 9b75140cca47257116498f0384fbf10a 323 Pfam PF01992 ATP synthase (C/AC39) subunit 8 318 3.2E-51 T 14-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0819 9b75140cca47257116498f0384fbf10a 323 Gene3D G3DSA:1.20.1690.10 78 178 1.6E-93 T 14-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0819 9b75140cca47257116498f0384fbf10a 323 Gene3D G3DSA:1.10.132.50 5 315 1.6E-93 T 14-10-2018 Theos_0819 9b75140cca47257116498f0384fbf10a 323 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 1 322 21.686 T 14-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 Theos_0819 9b75140cca47257116498f0384fbf10a 323 Gene3D G3DSA:1.20.1690.10 186 281 1.6E-93 T 14-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_1825 804316cfa059258e3e10131cdcdb80e2 212 Pfam PF08241 Methyltransferase domain 43 132 1.4E-22 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Theos_1825 804316cfa059258e3e10131cdcdb80e2 212 SUPERFAMILY SSF53335 3 170 8.06E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1825 804316cfa059258e3e10131cdcdb80e2 212 Gene3D G3DSA:3.40.50.150 12 212 2.5E-62 T 14-10-2018 Theos_0390 d03454872add8767ea8ce442b555abd0 569 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 3 203 3.0E-51 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_0390 d03454872add8767ea8ce442b555abd0 569 Gene3D G3DSA:3.60.9.10 1 208 1.7E-52 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Theos_0390 d03454872add8767ea8ce442b555abd0 569 SUPERFAMILY SSF48310 210 551 3.66E-75 T 14-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_0390 d03454872add8767ea8ce442b555abd0 569 Gene3D G3DSA:1.10.599.10 240 550 1.2E-51 T 14-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 Theos_0390 d03454872add8767ea8ce442b555abd0 569 SMART SM00790 3 208 5.1E-76 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_0390 d03454872add8767ea8ce442b555abd0 569 SUPERFAMILY SSF56228 3 203 1.44E-49 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Theos_0390 d03454872add8767ea8ce442b555abd0 569 Gene3D G3DSA:1.10.569.10 241 419 1.2E-51 T 14-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 Theos_0390 d03454872add8767ea8ce442b555abd0 569 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 221 549 3.3E-54 T 14-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_0974 b2740242b2b7e04e5fc31cdb939144d3 319 SUPERFAMILY SSF54593 1 261 1.63E-45 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_0974 b2740242b2b7e04e5fc31cdb939144d3 319 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 2 294 5.9E-133 T 14-10-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type Theos_0974 b2740242b2b7e04e5fc31cdb939144d3 319 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 231 252 - T 14-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 Theos_0974 b2740242b2b7e04e5fc31cdb939144d3 319 Gene3D G3DSA:3.10.180.10 1 134 1.4E-31 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_0974 b2740242b2b7e04e5fc31cdb939144d3 319 Gene3D G3DSA:3.10.180.10 136 294 3.6E-46 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_0974 b2740242b2b7e04e5fc31cdb939144d3 319 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 136 253 6.5E-16 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Theos_0974 b2740242b2b7e04e5fc31cdb939144d3 319 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 45 3.0E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Theos_0918 abca16b6e4bc17e3c907782e2dd8b802 287 SUPERFAMILY SSF47090 212 263 4.97E-9 T 14-10-2018 IPR036365 PGBD-like superfamily Theos_0918 abca16b6e4bc17e3c907782e2dd8b802 287 Pfam PF06267 Family of unknown function (DUF1028) 6 201 8.3E-75 T 14-10-2018 IPR010430 Protein of unknown function DUF1028 Theos_0918 abca16b6e4bc17e3c907782e2dd8b802 287 Gene3D G3DSA:1.10.101.10 215 272 3.1E-7 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 Theos_0918 abca16b6e4bc17e3c907782e2dd8b802 287 SUPERFAMILY SSF56235 6 214 8.49E-70 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_0918 abca16b6e4bc17e3c907782e2dd8b802 287 Pfam PF08823 Putative peptidoglycan binding domain 212 278 2.3E-17 T 14-10-2018 IPR014927 Putative peptidoglycan binding Theos_0918 abca16b6e4bc17e3c907782e2dd8b802 287 Gene3D G3DSA:3.60.20.10 4 214 5.5E-76 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_1444 c016baa7af4c7205b24d8c321a425621 438 Gene3D G3DSA:2.40.50.140 2 97 2.3E-22 T 14-10-2018 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 Pfam PF01336 OB-fold nucleic acid binding domain 16 94 6.5E-14 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 SUPERFAMILY SSF55681 111 432 6.77E-87 T 14-10-2018 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 5.5E-15 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 198 211 5.5E-15 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 182 194 5.5E-15 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 5.5E-15 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 113 432 1.0E-75 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 6 436 1.1E-142 T 14-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 SUPERFAMILY SSF50249 4 96 1.56E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1444 c016baa7af4c7205b24d8c321a425621 438 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 438 41.771 T 14-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 Theos_1444 c016baa7af4c7205b24d8c321a425621 438 Gene3D G3DSA:3.30.930.10 102 438 1.1E-102 T 14-10-2018 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 SUPERFAMILY SSF47413 5 63 2.82E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 Pfam PF13377 Periplasmic binding protein-like domain 168 324 1.8E-35 T 14-10-2018 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 17 27 9.2E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 7 17 9.2E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 2.4E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 SUPERFAMILY SSF53822 66 325 1.55E-65 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 SMART SM00354 5 75 1.3E-27 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 Gene3D G3DSA:3.40.50.2300 160 286 6.6E-70 T 14-10-2018 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 Gene3D G3DSA:1.10.260.40 1 58 6.8E-21 T 14-10-2018 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 Gene3D G3DSA:3.40.50.2300 59 302 6.6E-70 T 14-10-2018 Theos_2289 ad581bb32d4a807b58717d00ce90fc9a 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 14-10-2018 Theos_1818 1e769c6ebbb1c0bbc867550cfc13ac26 351 Gene3D G3DSA:3.40.50.1100 60 156 2.0E-132 T 14-10-2018 Theos_1818 1e769c6ebbb1c0bbc867550cfc13ac26 351 TIGRFAM TIGR00260 thrC: threonine synthase 6 324 2.3E-91 T 14-10-2018 IPR004450 Threonine synthase-like Theos_1818 1e769c6ebbb1c0bbc867550cfc13ac26 351 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Theos_1818 1e769c6ebbb1c0bbc867550cfc13ac26 351 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 318 9.8E-72 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Theos_1818 1e769c6ebbb1c0bbc867550cfc13ac26 351 PIRSF PIRSF038945 2 350 1.4E-160 T 14-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 Theos_1818 1e769c6ebbb1c0bbc867550cfc13ac26 351 SUPERFAMILY SSF53686 6 344 1.2E-99 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Theos_1818 1e769c6ebbb1c0bbc867550cfc13ac26 351 Gene3D G3DSA:3.40.50.1100 8 324 2.0E-132 T 14-10-2018 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 SUPERFAMILY SSF55120 59 220 7.91E-38 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 96 110 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 SMART SM00363 1 59 9.0E-15 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 Gene3D G3DSA:3.30.70.1560 120 206 1.2E-48 T 14-10-2018 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 64 217 1.0E-41 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 Pfam PF00849 RNA pseudouridylate synthase 60 140 6.9E-14 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 SUPERFAMILY SSF55174 1 88 5.45E-20 T 14-10-2018 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 Gene3D G3DSA:3.30.70.580 62 214 1.2E-48 T 14-10-2018 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 Gene3D G3DSA:3.10.290.10 1 54 3.3E-24 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Theos_2112 b506bda23d83e9c3c01d3444ce2195f7 232 Pfam PF01479 S4 domain 1 46 1.3E-13 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_1668 1fefecd49fe70116b6dd7866473bd5d4 560 Gene3D G3DSA:3.40.50.12780 18 455 8.8E-133 T 14-10-2018 Theos_1668 1fefecd49fe70116b6dd7866473bd5d4 560 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 14-10-2018 IPR020845 AMP-binding, conserved site Theos_1668 1fefecd49fe70116b6dd7866473bd5d4 560 Gene3D G3DSA:3.30.300.310 456 560 4.9E-36 T 14-10-2018 Theos_1668 1fefecd49fe70116b6dd7866473bd5d4 560 SUPERFAMILY SSF56801 18 556 3.4E-171 T 14-10-2018 Theos_1668 1fefecd49fe70116b6dd7866473bd5d4 560 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 545 7.8E-23 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Theos_1668 1fefecd49fe70116b6dd7866473bd5d4 560 Pfam PF00501 AMP-binding enzyme 32 458 1.4E-120 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_0381 43316243e0f0231bee93f7db015baf2e 225 Pfam PF02602 Uroporphyrinogen-III synthase HemD 11 216 4.2E-40 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_0381 43316243e0f0231bee93f7db015baf2e 225 Gene3D G3DSA:3.40.50.10090 112 221 1.3E-15 T 14-10-2018 Theos_0381 43316243e0f0231bee93f7db015baf2e 225 Gene3D G3DSA:3.40.50.10090 1 111 3.4E-12 T 14-10-2018 Theos_0381 43316243e0f0231bee93f7db015baf2e 225 SUPERFAMILY SSF69618 2 224 1.96E-42 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2520 e08d5076491e3fa6020e1bc3bffd924b 83 SUPERFAMILY SSF143880 6 77 1.44E-17 T 14-10-2018 IPR036782 NE0471-like, N-terminal Theos_2520 e08d5076491e3fa6020e1bc3bffd924b 83 Gene3D G3DSA:3.30.2020.10 2 78 4.7E-8 T 14-10-2018 IPR036782 NE0471-like, N-terminal Theos_2520 e08d5076491e3fa6020e1bc3bffd924b 83 Pfam PF10387 Protein of unknown function (DUF2442) 9 79 1.6E-16 T 14-10-2018 IPR018841 Protein of unknown function DUF2442 Theos_0690 6450470ce93ecceb37b330a9df492d8d 228 Gene3D G3DSA:3.60.21.10 1 228 5.2E-98 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_0690 6450470ce93ecceb37b330a9df492d8d 228 SUPERFAMILY SSF56300 3 223 8.28E-44 T 14-10-2018 Theos_0690 6450470ce93ecceb37b330a9df492d8d 228 Pfam PF14582 Metallophosphoesterase, calcineurin superfamily 1 227 1.5E-66 T 14-10-2018 IPR029461 Metallophosphoesterase, TT1561-like Theos_0304 13f728f15407ed1baa11df81768ac019 209 Pfam PF01479 S4 domain 100 146 3.5E-23 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0304 13f728f15407ed1baa11df81768ac019 209 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 98 7.5E-32 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 Theos_0304 13f728f15407ed1baa11df81768ac019 209 Gene3D G3DSA:1.10.1050.10 6 209 1.8E-94 T 14-10-2018 Theos_0304 13f728f15407ed1baa11df81768ac019 209 SMART SM00363 99 163 9.6E-22 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0304 13f728f15407ed1baa11df81768ac019 209 ProSitePatterns PS00632 Ribosomal protein S4 signature. 97 121 - T 14-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0304 13f728f15407ed1baa11df81768ac019 209 SMART SM01390 3 98 1.6E-56 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 Theos_0304 13f728f15407ed1baa11df81768ac019 209 SUPERFAMILY SSF55174 3 209 2.62E-76 T 14-10-2018 Theos_0304 13f728f15407ed1baa11df81768ac019 209 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 209 37.514 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Theos_0304 13f728f15407ed1baa11df81768ac019 209 Gene3D G3DSA:3.10.290.10 98 194 1.8E-94 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Theos_0304 13f728f15407ed1baa11df81768ac019 209 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 209 1.9E-77 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Theos_1585 0b3b379f4f2c717849a629d2e50ffda1 314 Gene3D G3DSA:3.30.70.20 234 304 6.0E-12 T 14-10-2018 Theos_1585 0b3b379f4f2c717849a629d2e50ffda1 314 Gene3D G3DSA:3.30.70.20 27 89 2.5E-10 T 14-10-2018 Theos_1585 0b3b379f4f2c717849a629d2e50ffda1 314 Pfam PF12798 4Fe-4S binding domain 35 47 0.095 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1585 0b3b379f4f2c717849a629d2e50ffda1 314 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 273 284 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1585 0b3b379f4f2c717849a629d2e50ffda1 314 Pfam PF13237 4Fe-4S dicluster domain 236 284 2.5E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1585 0b3b379f4f2c717849a629d2e50ffda1 314 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 240 251 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1585 0b3b379f4f2c717849a629d2e50ffda1 314 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1585 0b3b379f4f2c717849a629d2e50ffda1 314 Pfam PF00037 4Fe-4S binding domain 56 77 4.8E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1585 0b3b379f4f2c717849a629d2e50ffda1 314 SUPERFAMILY SSF54862 19 291 3.53E-22 T 14-10-2018 Theos_0536 58e4e741dddc6ae095b76e7355904853 440 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 423 1.3E-143 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Theos_0536 58e4e741dddc6ae095b76e7355904853 440 Pfam PF04055 Radical SAM superfamily 142 312 2.2E-33 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_0536 58e4e741dddc6ae095b76e7355904853 440 SUPERFAMILY SSF102114 105 365 2.62E-67 T 14-10-2018 Theos_0536 58e4e741dddc6ae095b76e7355904853 440 Gene3D G3DSA:3.80.30.20 137 369 8.4E-87 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Theos_0536 58e4e741dddc6ae095b76e7355904853 440 SMART SM00729 138 355 2.1E-64 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_0536 58e4e741dddc6ae095b76e7355904853 440 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 427 5.0E-135 T 14-10-2018 Theos_0536 58e4e741dddc6ae095b76e7355904853 440 Gene3D G3DSA:3.40.50.12160 1 127 1.6E-26 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Theos_0536 58e4e741dddc6ae095b76e7355904853 440 Pfam PF00919 Uncharacterized protein family UPF0004 2 100 7.2E-25 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Theos_0536 58e4e741dddc6ae095b76e7355904853 440 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 427 64.918 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 Theos_0536 58e4e741dddc6ae095b76e7355904853 440 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Theos_1473 75f1fd89688fcdae6708c1243264251e 817 SUPERFAMILY SSF54631 303 427 1.11E-10 T 14-10-2018 Theos_1473 75f1fd89688fcdae6708c1243264251e 817 Pfam PF01368 DHH family 3 141 9.2E-7 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Theos_1473 75f1fd89688fcdae6708c1243264251e 817 Gene3D G3DSA:3.10.580.10 301 431 3.4E-8 T 14-10-2018 Theos_1473 75f1fd89688fcdae6708c1243264251e 817 SUPERFAMILY SSF81301 448 583 3.27E-28 T 14-10-2018 Theos_1473 75f1fd89688fcdae6708c1243264251e 817 SUPERFAMILY SSF64182 3 290 2.49E-41 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily Theos_1473 75f1fd89688fcdae6708c1243264251e 817 Gene3D G3DSA:1.10.3090.10 582 805 1.1E-29 T 14-10-2018 Theos_1473 75f1fd89688fcdae6708c1243264251e 817 Pfam PF00571 CBS domain 309 362 1.2E-4 T 14-10-2018 IPR000644 CBS domain Theos_1473 75f1fd89688fcdae6708c1243264251e 817 Gene3D G3DSA:3.90.1640.10 2 173 4.7E-25 T 14-10-2018 Theos_1473 75f1fd89688fcdae6708c1243264251e 817 SUPERFAMILY SSF81891 585 807 7.06E-27 T 14-10-2018 Theos_1473 75f1fd89688fcdae6708c1243264251e 817 Gene3D G3DSA:3.30.460.10 432 581 1.3E-34 T 14-10-2018 Theos_1473 75f1fd89688fcdae6708c1243264251e 817 Pfam PF01743 Poly A polymerase head domain 460 586 4.0E-22 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 426 3.9E-147 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 SUPERFAMILY SSF52540 135 430 1.25E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 SUPERFAMILY SSF52540 2 161 2.73E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 346 426 2.6E-25 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 PIRSF PIRSF006485 1 434 2.5E-151 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 Gene3D G3DSA:3.30.300.20 351 429 5.3E-24 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 Hamap MF_00195 GTPase Der [der]. 1 429 34.654 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 Gene3D G3DSA:3.40.50.300 173 350 8.9E-48 T 14-10-2018 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 244 262 2.8E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 176 196 2.8E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 174 335 3.1E-28 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 155 1.4E-26 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 Gene3D G3DSA:3.40.50.300 1 161 1.7E-47 T 14-10-2018 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 Pfam PF01926 50S ribosome-binding GTPase 3 117 2.0E-27 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0426 84703ad175294bf86aed69b5a14aabd9 435 Pfam PF01926 50S ribosome-binding GTPase 176 290 4.2E-25 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0822 91a9bedbaba3203a70824077e1807fb3 475 Gene3D G3DSA:3.40.50.12240 1 464 2.9E-189 T 14-10-2018 Theos_0822 91a9bedbaba3203a70824077e1807fb3 475 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 11 68 2.4E-8 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_0822 91a9bedbaba3203a70824077e1807fb3 475 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_0822 91a9bedbaba3203a70824077e1807fb3 475 SUPERFAMILY SSF52540 82 364 3.83E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0822 91a9bedbaba3203a70824077e1807fb3 475 SUPERFAMILY SSF47917 372 425 3.14E-6 T 14-10-2018 Theos_0822 91a9bedbaba3203a70824077e1807fb3 475 PIRSF PIRSF039114 1 472 5.0E-241 T 14-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0822 91a9bedbaba3203a70824077e1807fb3 475 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 5 467 59.105 T 14-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0822 91a9bedbaba3203a70824077e1807fb3 475 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 134 359 5.0E-66 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_2222 63e4a63d89462fbe2369cf7986922aab 400 Gene3D G3DSA:3.30.9.10 77 385 5.3E-143 T 14-10-2018 Theos_2222 63e4a63d89462fbe2369cf7986922aab 400 SUPERFAMILY SSF51905 5 373 8.98E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2222 63e4a63d89462fbe2369cf7986922aab 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 7.8E-28 T 14-10-2018 Theos_2222 63e4a63d89462fbe2369cf7986922aab 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 7.8E-28 T 14-10-2018 Theos_2222 63e4a63d89462fbe2369cf7986922aab 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 7.8E-28 T 14-10-2018 Theos_2222 63e4a63d89462fbe2369cf7986922aab 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 7.8E-28 T 14-10-2018 Theos_2222 63e4a63d89462fbe2369cf7986922aab 400 Gene3D G3DSA:3.50.50.60 5 351 5.3E-143 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2222 63e4a63d89462fbe2369cf7986922aab 400 SUPERFAMILY SSF54373 177 275 6.67E-35 T 14-10-2018 Theos_2222 63e4a63d89462fbe2369cf7986922aab 400 Pfam PF01494 FAD binding domain 4 340 1.6E-64 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 PRINTS PR00974 Ribosomal protein S18 family signature 50 57 1.6E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 PRINTS PR00974 Ribosomal protein S18 family signature 40 50 1.6E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 PRINTS PR00974 Ribosomal protein S18 family signature 72 82 1.6E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 PRINTS PR00974 Ribosomal protein S18 family signature 58 72 1.6E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 TIGRFAM TIGR00165 S18: ribosomal protein bS18 29 85 1.5E-21 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 Gene3D G3DSA:4.10.640.10 1 89 3.0E-34 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 Pfam PF01084 Ribosomal protein S18 34 80 3.8E-22 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 SUPERFAMILY SSF46911 17 85 5.1E-23 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 11 85 19.949 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2122 ac42b6759190879ba169c8f56f5b9c56 89 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 34 83 2.0E-20 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1051 1a1c21c13a2fcacfd6ecc7f8bccfb9d0 376 Pfam PF04055 Radical SAM superfamily 16 169 1.7E-19 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_1051 1a1c21c13a2fcacfd6ecc7f8bccfb9d0 376 Gene3D G3DSA:3.20.20.70 5 320 4.4E-42 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1051 1a1c21c13a2fcacfd6ecc7f8bccfb9d0 376 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 5 361 1.9E-144 T 14-10-2018 IPR027634 Radical SAM protein, BA_1875 family Theos_1051 1a1c21c13a2fcacfd6ecc7f8bccfb9d0 376 PIRSF PIRSF037420 3 366 2.7E-92 T 14-10-2018 IPR017200 Coenzyme PQQ synthesis protein E Theos_1051 1a1c21c13a2fcacfd6ecc7f8bccfb9d0 376 Pfam PF13186 Iron-sulfur cluster-binding domain 277 330 1.6E-5 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain Theos_1051 1a1c21c13a2fcacfd6ecc7f8bccfb9d0 376 SMART SM00729 11 214 1.8E-4 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_1051 1a1c21c13a2fcacfd6ecc7f8bccfb9d0 376 SUPERFAMILY SSF102114 5 338 1.14E-65 T 14-10-2018 Theos_0330 678b5ae814c40abe2f84450fdb9e2c96 463 Pfam PF00156 Phosphoribosyl transferase domain 271 382 7.8E-11 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Theos_0330 678b5ae814c40abe2f84450fdb9e2c96 463 SUPERFAMILY SSF53271 245 452 3.28E-67 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_0330 678b5ae814c40abe2f84450fdb9e2c96 463 SUPERFAMILY SSF56235 8 252 1.2E-60 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_0330 678b5ae814c40abe2f84450fdb9e2c96 463 Pfam PF13537 Glutamine amidotransferase domain 92 209 4.2E-21 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Theos_0330 678b5ae814c40abe2f84450fdb9e2c96 463 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 8 448 7.4E-151 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Theos_0330 678b5ae814c40abe2f84450fdb9e2c96 463 Gene3D G3DSA:3.40.50.2020 270 433 7.3E-146 T 14-10-2018 Theos_0330 678b5ae814c40abe2f84450fdb9e2c96 463 Gene3D G3DSA:3.60.20.10 8 448 7.3E-146 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_0330 678b5ae814c40abe2f84450fdb9e2c96 463 PIRSF PIRSF000485 4 463 4.8E-161 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Theos_0330 678b5ae814c40abe2f84450fdb9e2c96 463 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 7 447 44.231 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Theos_1345 ec9633e2ffd7b35a7176840cc3466505 512 Gene3D G3DSA:3.20.20.70 160 346 5.5E-164 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1345 ec9633e2ffd7b35a7176840cc3466505 512 SUPERFAMILY SSF51690 148 504 2.35E-98 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 Theos_1345 ec9633e2ffd7b35a7176840cc3466505 512 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 7 493 6.5E-133 T 14-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 Theos_1345 ec9633e2ffd7b35a7176840cc3466505 512 Gene3D G3DSA:3.20.140.10 7 497 5.5E-164 T 14-10-2018 Theos_1345 ec9633e2ffd7b35a7176840cc3466505 512 SUPERFAMILY SSF54675 5 153 6.73E-35 T 14-10-2018 Theos_1345 ec9633e2ffd7b35a7176840cc3466505 512 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 192 383 3.9E-4 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 Theos_1345 ec9633e2ffd7b35a7176840cc3466505 512 PIRSF PIRSF000484 1 506 1.8E-144 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 Theos_2167 235c42b0a9e6ef6d3d66021e78d3bb67 377 Gene3D G3DSA:1.20.1250.20 2 369 3.2E-44 T 14-10-2018 Theos_2167 235c42b0a9e6ef6d3d66021e78d3bb67 377 ProSitePatterns PS00216 Sugar transport proteins signature 1. 250 266 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Theos_2167 235c42b0a9e6ef6d3d66021e78d3bb67 377 Pfam PF07690 Major Facilitator Superfamily 10 335 3.8E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_2167 235c42b0a9e6ef6d3d66021e78d3bb67 377 SUPERFAMILY SSF103473 5 370 1.44E-50 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1488 99ebf7cc71a736829b4e3875dc81adb5 164 Pfam PF00364 Biotin-requiring enzyme 88 161 3.5E-25 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Theos_1488 99ebf7cc71a736829b4e3875dc81adb5 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 91 104 1.3E-18 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Theos_1488 99ebf7cc71a736829b4e3875dc81adb5 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 123 136 1.3E-18 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Theos_1488 99ebf7cc71a736829b4e3875dc81adb5 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 108 122 1.3E-18 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Theos_1488 99ebf7cc71a736829b4e3875dc81adb5 164 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 162 5.4E-46 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Theos_1488 99ebf7cc71a736829b4e3875dc81adb5 164 SUPERFAMILY SSF51230 86 161 3.14E-26 T 14-10-2018 IPR011053 Single hybrid motif Theos_1488 99ebf7cc71a736829b4e3875dc81adb5 164 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 118 135 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Theos_1488 99ebf7cc71a736829b4e3875dc81adb5 164 Gene3D G3DSA:2.40.50.100 86 161 8.7E-34 T 14-10-2018 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 210 4.7E-23 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 116 2.2E-32 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 329 348 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 SUPERFAMILY SSF47203 220 372 2.09E-58 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 SUPERFAMILY SSF56645 2 235 1.57E-77 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 Gene3D G3DSA:2.40.110.10 119 227 2.1E-36 T 14-10-2018 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 Gene3D G3DSA:1.20.140.10 228 373 6.0E-55 T 14-10-2018 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 222 370 2.4E-51 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 PIRSF PIRSF016578 2 372 4.2E-22 T 14-10-2018 Theos_1942 0d325bc1e3bbf66c15a587d27cb6a84c 373 Gene3D G3DSA:1.10.540.10 1 118 1.4E-36 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Theos_2513 fa3cf24d71cdb7bdaaba862088bf3e34 354 SUPERFAMILY SSF53098 182 338 1.09E-26 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_2513 fa3cf24d71cdb7bdaaba862088bf3e34 354 SUPERFAMILY SSF46689 42 140 7.17E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_2513 fa3cf24d71cdb7bdaaba862088bf3e34 354 Pfam PF13384 Homeodomain-like domain 31 80 1.2E-12 T 14-10-2018 Theos_2513 fa3cf24d71cdb7bdaaba862088bf3e34 354 Pfam PF13683 Integrase core domain 266 331 1.9E-18 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Theos_2513 fa3cf24d71cdb7bdaaba862088bf3e34 354 Gene3D G3DSA:3.30.420.10 181 346 6.3E-14 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Theos_2104 bd62af5305a0f1d60bbbd0370c716166 295 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 2 291 27.353 T 14-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 Theos_2104 bd62af5305a0f1d60bbbd0370c716166 295 SUPERFAMILY SSF46785 8 53 9.87E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2104 bd62af5305a0f1d60bbbd0370c716166 295 Pfam PF03099 Biotin/lipoate A/B protein ligase family 77 196 8.7E-8 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Theos_2104 bd62af5305a0f1d60bbbd0370c716166 295 Gene3D G3DSA:3.30.930.10 58 249 7.1E-42 T 14-10-2018 Theos_2104 bd62af5305a0f1d60bbbd0370c716166 295 SUPERFAMILY SSF55681 64 245 4.22E-39 T 14-10-2018 Theos_2104 bd62af5305a0f1d60bbbd0370c716166 295 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 74 281 1.8E-39 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Theos_2104 bd62af5305a0f1d60bbbd0370c716166 295 Gene3D G3DSA:1.10.10.10 3 54 1.4E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2104 bd62af5305a0f1d60bbbd0370c716166 295 Pfam PF08279 HTH domain 9 51 8.1E-7 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 Theos_2104 bd62af5305a0f1d60bbbd0370c716166 295 Gene3D G3DSA:2.30.30.100 250 291 3.7E-6 T 14-10-2018 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 378 1.8E-28 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 220 1.1E-23 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 SUPERFAMILY SSF56645 3 231 1.83E-76 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 SUPERFAMILY SSF47203 236 383 8.22E-39 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 124 2.5E-36 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 Gene3D G3DSA:2.40.110.10 127 231 9.7E-35 T 14-10-2018 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 Gene3D G3DSA:1.10.540.10 1 125 1.8E-42 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_0564 3da14e298d4f099b8f62916f8f7f3b7f 385 Gene3D G3DSA:1.20.140.10 236 385 5.2E-37 T 14-10-2018 Theos_0972 8e4b46ad0245196ed926d67b78a61b01 484 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 273 471 1.2E-70 T 14-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal Theos_0972 8e4b46ad0245196ed926d67b78a61b01 484 SUPERFAMILY SSF56645 1 266 1.69E-79 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_0972 8e4b46ad0245196ed926d67b78a61b01 484 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 266 5.7E-97 T 14-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal Theos_0972 8e4b46ad0245196ed926d67b78a61b01 484 TIGRFAM TIGR02309 HpaB-1: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 2 473 1.5E-260 T 14-10-2018 IPR012687 4-HPA 3-monooxygenase large component, Deinococcus-type GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 Theos_0972 8e4b46ad0245196ed926d67b78a61b01 484 Gene3D G3DSA:2.40.110.10 139 268 1.7E-47 T 14-10-2018 Theos_0972 8e4b46ad0245196ed926d67b78a61b01 484 Gene3D G3DSA:1.20.140.10 269 484 5.4E-93 T 14-10-2018 Theos_0972 8e4b46ad0245196ed926d67b78a61b01 484 PIRSF PIRSF000331 1 481 1.0E-184 T 14-10-2018 IPR004925 HpaB/PvcC/4-BUDH Theos_0972 8e4b46ad0245196ed926d67b78a61b01 484 Gene3D G3DSA:1.10.3140.10 1 138 5.4E-60 T 14-10-2018 Theos_0972 8e4b46ad0245196ed926d67b78a61b01 484 SUPERFAMILY SSF47203 257 471 9.9E-65 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_1066 49d205b46daa7135721803f7f72b3e69 364 SUPERFAMILY SSF50129 34 194 3.3E-25 T 14-10-2018 IPR011032 GroES-like superfamily Theos_1066 49d205b46daa7135721803f7f72b3e69 364 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 45 156 4.3E-13 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Theos_1066 49d205b46daa7135721803f7f72b3e69 364 Gene3D G3DSA:3.90.180.10 41 350 2.8E-62 T 14-10-2018 Theos_1066 49d205b46daa7135721803f7f72b3e69 364 SUPERFAMILY SSF51735 162 328 9.93E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1066 49d205b46daa7135721803f7f72b3e69 364 Gene3D G3DSA:3.40.50.720 174 313 2.8E-62 T 14-10-2018 Theos_1066 49d205b46daa7135721803f7f72b3e69 364 Pfam PF00107 Zinc-binding dehydrogenase 196 328 1.4E-18 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Theos_1536 13f80145b8c58d787c13d2595e1c5a6c 565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 14-10-2018 IPR020845 AMP-binding, conserved site Theos_1536 13f80145b8c58d787c13d2595e1c5a6c 565 Pfam PF00501 AMP-binding enzyme 31 465 6.7E-118 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_1536 13f80145b8c58d787c13d2595e1c5a6c 565 Gene3D G3DSA:3.30.300.310 463 563 4.3E-35 T 14-10-2018 Theos_1536 13f80145b8c58d787c13d2595e1c5a6c 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 475 552 3.4E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Theos_1536 13f80145b8c58d787c13d2595e1c5a6c 565 SUPERFAMILY SSF56801 18 562 3.53E-168 T 14-10-2018 Theos_1536 13f80145b8c58d787c13d2595e1c5a6c 565 Gene3D G3DSA:3.40.50.12780 16 462 3.9E-129 T 14-10-2018 Theos_0136 683b9a423fbc5eab2f36a30150f3d72d 248 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 117 220 3.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0136 683b9a423fbc5eab2f36a30150f3d72d 248 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 117 214 6.8E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0136 683b9a423fbc5eab2f36a30150f3d72d 248 Gene3D G3DSA:3.40.50.1000 5 240 2.9E-44 T 14-10-2018 IPR023214 HAD superfamily Theos_0136 683b9a423fbc5eab2f36a30150f3d72d 248 SUPERFAMILY SSF56784 1 243 2.07E-44 T 14-10-2018 IPR036412 HAD-like superfamily Theos_0136 683b9a423fbc5eab2f36a30150f3d72d 248 Gene3D G3DSA:1.20.120.1600 15 117 2.9E-44 T 14-10-2018 Theos_0136 683b9a423fbc5eab2f36a30150f3d72d 248 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 220 9.3E-23 T 14-10-2018 Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 Gene3D G3DSA:3.40.50.720 3 349 1.5E-140 T 14-10-2018 Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 SMART SM01003 4 135 1.5E-76 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 SMART SM01002 147 295 4.5E-88 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 Gene3D G3DSA:3.40.50.720 128 303 1.5E-140 T 14-10-2018 Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 SUPERFAMILY SSF51735 135 301 2.15E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 367 4.9E-172 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 171 196 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 SUPERFAMILY SSF52283 1 357 1.7E-67 T 14-10-2018 Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 135 2.5E-43 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 139 349 1.2E-87 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Theos_2115 084eb1bd18b662e5a9f868e4c66a6891 369 PIRSF PIRSF000183 1 368 1.4E-186 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 895 0.0 T 14-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 SUPERFAMILY SSF53732 3 632 6.67E-229 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 Gene3D G3DSA:3.30.499.20 3 372 5.6E-159 T 14-10-2018 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 Pfam PF00694 Aconitase C-terminal domain 696 822 5.9E-45 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 ProSitePatterns PS00450 Aconitase family signature 1. 433 449 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 Gene3D G3DSA:3.30.499.10 373 596 5.1E-106 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 Gene3D G3DSA:3.20.19.10 658 896 2.4E-104 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 Pfam PF00330 Aconitase family (aconitate hydratase) 77 568 1.7E-181 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 SUPERFAMILY SSF52016 637 893 7.46E-84 T 14-10-2018 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 Gene3D G3DSA:1.10.1440.20 597 657 1.6E-23 T 14-10-2018 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 PRINTS PR00415 Aconitase family signature 168 176 2.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 PRINTS PR00415 Aconitase family signature 144 157 2.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 PRINTS PR00415 Aconitase family signature 201 214 2.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 PRINTS PR00415 Aconitase family signature 437 448 2.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 PRINTS PR00415 Aconitase family signature 291 304 2.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 PRINTS PR00415 Aconitase family signature 277 290 2.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 PRINTS PR00415 Aconitase family signature 372 386 2.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 PRINTS PR00415 Aconitase family signature 215 230 2.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1424 829ca7206e349cc35dac0abc3d35c2b9 901 PRINTS PR00415 Aconitase family signature 499 512 2.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_2032 b7b96ad9d10ba02d8d848c97694fc1f0 221 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 145 3.1E-27 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 Theos_2032 b7b96ad9d10ba02d8d848c97694fc1f0 221 SUPERFAMILY SSF102588 1 208 1.44E-47 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_2032 b7b96ad9d10ba02d8d848c97694fc1f0 221 Gene3D G3DSA:3.40.50.10320 2 209 8.7E-41 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 Hamap MF_00235 Adenylate kinase [adk]. 3 183 44.056 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 ProSitePatterns PS00113 Adenylate kinase signature. 78 89 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 Gene3D G3DSA:3.40.50.300 2 184 4.9E-66 T 14-10-2018 Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 PRINTS PR00094 Adenylate kinase signature 34 48 4.2E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 PRINTS PR00094 Adenylate kinase signature 78 94 4.2E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 PRINTS PR00094 Adenylate kinase signature 6 19 4.2E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 PRINTS PR00094 Adenylate kinase signature 130 145 4.2E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 PRINTS PR00094 Adenylate kinase signature 147 161 4.2E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 SUPERFAMILY SSF52540 4 182 7.06E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0298 8330b8ceb264ca510ec1ccab1376029a 184 Pfam PF00406 Adenylate kinase 8 160 3.6E-49 T 14-10-2018 Theos_0141 5bb4031dd67afaca8849d7c3c830035a 356 Pfam PF07687 Peptidase dimerisation domain 157 246 4.4E-9 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain Theos_0141 5bb4031dd67afaca8849d7c3c830035a 356 Gene3D G3DSA:3.30.70.360 159 273 3.9E-72 T 14-10-2018 Theos_0141 5bb4031dd67afaca8849d7c3c830035a 356 Pfam PF01546 Peptidase family M20/M25/M40 59 350 8.1E-28 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 Theos_0141 5bb4031dd67afaca8849d7c3c830035a 356 SUPERFAMILY SSF55031 162 250 8.52E-10 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Theos_0141 5bb4031dd67afaca8849d7c3c830035a 356 Gene3D G3DSA:3.40.630.10 11 341 3.9E-72 T 14-10-2018 Theos_0141 5bb4031dd67afaca8849d7c3c830035a 356 SUPERFAMILY SSF53187 2 354 3.83E-50 T 14-10-2018 Theos_1821 e421dff3076e4082d7a3627fdd7c0d8d 234 Gene3D G3DSA:3.60.21.10 1 230 2.2E-45 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_1821 e421dff3076e4082d7a3627fdd7c0d8d 234 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 192 4.6E-21 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 Theos_1821 e421dff3076e4082d7a3627fdd7c0d8d 234 SUPERFAMILY SSF56300 1 229 5.54E-51 T 14-10-2018 Theos_1821 e421dff3076e4082d7a3627fdd7c0d8d 234 PIRSF PIRSF000883 1 233 4.5E-43 T 14-10-2018 IPR011152 Phosphoesterase MJ0912 Theos_1658 2471c6e1646040a9d2e76adf68e777c3 232 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1658 2471c6e1646040a9d2e76adf68e777c3 232 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 224 2.9E-80 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1658 2471c6e1646040a9d2e76adf68e777c3 232 Gene3D G3DSA:1.10.1060.10 103 230 5.5E-46 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Theos_1658 2471c6e1646040a9d2e76adf68e777c3 232 Pfam PF13237 4Fe-4S dicluster domain 142 211 3.9E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1658 2471c6e1646040a9d2e76adf68e777c3 232 Gene3D G3DSA:3.10.20.30 1 102 8.8E-36 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Theos_1658 2471c6e1646040a9d2e76adf68e777c3 232 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 107 1.0E-36 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1658 2471c6e1646040a9d2e76adf68e777c3 232 SUPERFAMILY SSF54292 1 102 7.56E-32 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Theos_1658 2471c6e1646040a9d2e76adf68e777c3 232 SUPERFAMILY SSF46548 103 228 4.71E-32 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 Gene3D G3DSA:1.10.150.20 88 156 2.7E-22 T 14-10-2018 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 297 314 1.3E-9 T 14-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 240 248 1.3E-9 T 14-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 255 262 1.3E-9 T 14-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 60 77 1.3E-9 T 14-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 Gene3D G3DSA:3.20.20.140 327 575 4.8E-71 T 14-10-2018 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 SUPERFAMILY SSF89550 337 571 3.92E-48 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 Pfam PF14716 Helix-hairpin-helix domain 3 73 1.0E-19 T 14-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 Gene3D G3DSA:3.30.210.10 262 326 6.2E-27 T 14-10-2018 IPR037160 DNA polymerase, thumb domain superfamily Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 Gene3D G3DSA:3.30.460.10 157 261 1.5E-25 T 14-10-2018 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 Gene3D G3DSA:1.10.150.110 1 86 2.1E-24 T 14-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 SUPERFAMILY SSF47781 95 148 3.5E-8 T 14-10-2018 IPR010994 RuvA domain 2-like Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 Pfam PF02811 PHP domain 340 421 1.8E-6 T 14-10-2018 IPR004013 PHP domain GO:0003824 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 Pfam PF14520 Helix-hairpin-helix domain 95 148 7.0E-14 T 14-10-2018 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 Pfam PF14791 DNA polymerase beta thumb 256 315 5.9E-19 T 14-10-2018 IPR029398 DNA polymerase beta, thumb domain Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 SMART SM00278 93 112 0.024 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 SMART SM00278 53 72 0.0014 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 SMART SM00278 128 147 0.014 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 SUPERFAMILY SSF81301 157 315 9.16E-43 T 14-10-2018 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 SUPERFAMILY SSF47802 1 85 1.12E-19 T 14-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 PIRSF PIRSF005047 1 573 2.0E-223 T 14-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 SMART SM00483 1 315 1.5E-36 T 14-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 Theos_1515 21257bfd8b5a222971cda0eb99dc05b3 575 SMART SM00481 339 418 1.7E-14 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Theos_1169 f59d388515d93261bf50492d706c315f 387 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 383 29.039 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 Theos_1169 f59d388515d93261bf50492d706c315f 387 Gene3D G3DSA:3.30.1480.10 1 138 6.1E-37 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 Theos_1169 f59d388515d93261bf50492d706c315f 387 SMART SM00322 311 372 2.2E-4 T 14-10-2018 IPR004087 K Homology domain GO:0003676 Theos_1169 f59d388515d93261bf50492d706c315f 387 SMART SM00322 240 303 13.0 T 14-10-2018 IPR004087 K Homology domain GO:0003676 Theos_1169 f59d388515d93261bf50492d706c315f 387 Pfam PF00575 S1 RNA binding domain 141 206 1.3E-12 T 14-10-2018 IPR003029 S1 domain GO:0003676 Theos_1169 f59d388515d93261bf50492d706c315f 387 SUPERFAMILY SSF54814 211 287 2.18E-29 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Theos_1169 f59d388515d93261bf50492d706c315f 387 Gene3D G3DSA:2.40.50.140 145 208 2.0E-23 T 14-10-2018 Theos_1169 f59d388515d93261bf50492d706c315f 387 Pfam PF08529 NusA N-terminal domain 4 134 1.8E-32 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 Theos_1169 f59d388515d93261bf50492d706c315f 387 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 350 7.6E-125 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 Theos_1169 f59d388515d93261bf50492d706c315f 387 SMART SM00316 143 208 3.1E-13 T 14-10-2018 IPR022967 RNA-binding domain, S1 Theos_1169 f59d388515d93261bf50492d706c315f 387 Pfam PF13184 NusA-like KH domain 240 307 7.6E-29 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 Theos_1169 f59d388515d93261bf50492d706c315f 387 SUPERFAMILY SSF69705 1 136 1.44E-32 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 Theos_1169 f59d388515d93261bf50492d706c315f 387 SUPERFAMILY SSF50249 141 209 7.25E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1169 f59d388515d93261bf50492d706c315f 387 SUPERFAMILY SSF54814 289 350 1.9E-13 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Theos_1169 f59d388515d93261bf50492d706c315f 387 Gene3D G3DSA:3.30.300.20 209 287 5.3E-34 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_1169 f59d388515d93261bf50492d706c315f 387 Gene3D G3DSA:3.30.300.20 288 386 2.2E-25 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_1751 50c365a8d7ec39659fe4931a24f0fb33 121 SMART SM01022 8 96 1.4E-5 T 14-10-2018 IPR007374 ASCH domain Theos_1751 50c365a8d7ec39659fe4931a24f0fb33 121 Gene3D G3DSA:2.30.130.30 5 104 2.2E-35 T 14-10-2018 Theos_1751 50c365a8d7ec39659fe4931a24f0fb33 121 SUPERFAMILY SSF88697 4 113 2.49E-28 T 14-10-2018 IPR015947 PUA-like superfamily Theos_1751 50c365a8d7ec39659fe4931a24f0fb33 121 Pfam PF04266 ASCH domain 10 93 1.7E-9 T 14-10-2018 IPR007374 ASCH domain Theos_1044 72a70024c48bb5f24a8a8800f4870d47 222 Pfam PF13545 Crp-like helix-turn-helix domain 152 217 8.0E-13 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_1044 72a70024c48bb5f24a8a8800f4870d47 222 SUPERFAMILY SSF46785 150 219 1.7E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1044 72a70024c48bb5f24a8a8800f4870d47 222 SMART SM00419 165 212 1.8E-7 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_1044 72a70024c48bb5f24a8a8800f4870d47 222 Gene3D G3DSA:2.60.120.10 3 146 2.7E-40 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_1044 72a70024c48bb5f24a8a8800f4870d47 222 Pfam PF00027 Cyclic nucleotide-binding domain 31 118 7.6E-20 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_1044 72a70024c48bb5f24a8a8800f4870d47 222 SMART SM00100 12 132 2.1E-19 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_1044 72a70024c48bb5f24a8a8800f4870d47 222 Gene3D G3DSA:1.10.10.10 147 219 2.3E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1044 72a70024c48bb5f24a8a8800f4870d47 222 SUPERFAMILY SSF51206 7 147 9.82E-36 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 Gene3D G3DSA:1.20.1250.20 256 432 2.4E-22 T 14-10-2018 Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 Gene3D G3DSA:1.20.1720.10 12 245 7.4E-46 T 14-10-2018 Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 Pfam PF07690 Major Facilitator Superfamily 15 408 7.2E-52 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 SUPERFAMILY SSF103473 6 605 3.79E-68 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 426 2.7E-81 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 1.3E-11 T 14-10-2018 Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 1.3E-11 T 14-10-2018 Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 1.3E-11 T 14-10-2018 Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 1.3E-11 T 14-10-2018 Theos_0983 a54dba6e4bc9c628f42c062944bbaa0b 616 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 124 1.3E-11 T 14-10-2018 Theos_1469 74fd527cba369decd5789429bebb7bab 168 SUPERFAMILY SSF54106 21 64 7.46E-13 T 14-10-2018 Theos_1469 74fd527cba369decd5789429bebb7bab 168 Gene3D G3DSA:2.40.40.10 76 168 8.0E-37 T 14-10-2018 IPR036908 RlpA-like domain superfamily Theos_1469 74fd527cba369decd5789429bebb7bab 168 SMART SM00257 22 65 4.9E-16 T 14-10-2018 IPR018392 LysM domain Theos_1469 74fd527cba369decd5789429bebb7bab 168 Gene3D G3DSA:3.10.350.10 19 71 5.2E-20 T 14-10-2018 IPR036779 LysM domain superfamily Theos_1469 74fd527cba369decd5789429bebb7bab 168 SUPERFAMILY SSF50685 73 158 3.0E-15 T 14-10-2018 IPR036908 RlpA-like domain superfamily Theos_1469 74fd527cba369decd5789429bebb7bab 168 Pfam PF03330 Lytic transglycolase 78 165 6.3E-25 T 14-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain Theos_1469 74fd527cba369decd5789429bebb7bab 168 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 18 167 23.708 T 14-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 Theos_1469 74fd527cba369decd5789429bebb7bab 168 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 79 165 1.8E-41 T 14-10-2018 IPR012997 Rare lipoprotein A Theos_1469 74fd527cba369decd5789429bebb7bab 168 Pfam PF01476 LysM domain 23 64 6.3E-15 T 14-10-2018 IPR018392 LysM domain Theos_0768 b0105c773328089189b3037f9b8f6bad 424 SMART SM00382 82 228 7.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0768 b0105c773328089189b3037f9b8f6bad 424 PRINTS PR01874 DNA repair protein radA signature 197 225 5.4E-76 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 PRINTS PR01874 DNA repair protein radA signature 230 256 5.4E-76 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 PRINTS PR01874 DNA repair protein radA signature 304 327 5.4E-76 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 PRINTS PR01874 DNA repair protein radA signature 158 182 5.4E-76 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 PRINTS PR01874 DNA repair protein radA signature 74 102 5.4E-76 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 PRINTS PR01874 DNA repair protein radA signature 113 130 5.4E-76 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 PRINTS PR01874 DNA repair protein radA signature 8 32 5.4E-76 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 Pfam PF13541 Subunit ChlI of Mg-chelatase 335 409 6.0E-7 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 Hamap MF_01498 DNA repair protein RadA [radA]. 19 423 40.695 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 SUPERFAMILY SSF52540 62 275 2.66E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0768 b0105c773328089189b3037f9b8f6bad 424 TIGRFAM TIGR00416 sms: DNA repair protein RadA 2 410 6.6E-133 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 Gene3D G3DSA:3.40.50.300 59 266 3.6E-33 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 SUPERFAMILY SSF54211 237 423 9.1E-29 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_0768 b0105c773328089189b3037f9b8f6bad 424 Pfam PF13481 AAA domain 75 206 8.2E-12 T 14-10-2018 Theos_0768 b0105c773328089189b3037f9b8f6bad 424 Gene3D G3DSA:3.30.230.10 276 423 2.0E-10 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_0281 83ff2f21727381510310cefaa45e4f60 93 PIRSF PIRSF002144 1 93 2.0E-34 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0281 83ff2f21727381510310cefaa45e4f60 93 Gene3D G3DSA:3.30.860.10 1 93 7.4E-45 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0281 83ff2f21727381510310cefaa45e4f60 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 5.3E-46 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 Theos_0281 83ff2f21727381510310cefaa45e4f60 93 SUPERFAMILY SSF54570 3 85 5.89E-37 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0281 83ff2f21727381510310cefaa45e4f60 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.746 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0281 83ff2f21727381510310cefaa45e4f60 93 Pfam PF00203 Ribosomal protein S19 3 83 3.8E-37 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0281 83ff2f21727381510310cefaa45e4f60 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.0E-26 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0281 83ff2f21727381510310cefaa45e4f60 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.0E-26 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0281 83ff2f21727381510310cefaa45e4f60 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.0E-26 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0281 83ff2f21727381510310cefaa45e4f60 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_1254 2cdb9f7341aa6e92724768646deb0ab7 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 185 1.2E-4 T 14-10-2018 Theos_1254 2cdb9f7341aa6e92724768646deb0ab7 244 SUPERFAMILY SSF51735 2 232 7.16E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1254 2cdb9f7341aa6e92724768646deb0ab7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1254 2cdb9f7341aa6e92724768646deb0ab7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1254 2cdb9f7341aa6e92724768646deb0ab7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 5.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1254 2cdb9f7341aa6e92724768646deb0ab7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1254 2cdb9f7341aa6e92724768646deb0ab7 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1254 2cdb9f7341aa6e92724768646deb0ab7 244 Pfam PF00106 short chain dehydrogenase 3 194 2.8E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1254 2cdb9f7341aa6e92724768646deb0ab7 244 Gene3D G3DSA:3.40.50.720 1 242 1.1E-52 T 14-10-2018 Theos_0521 e01973de1713da7dd501324c9768dbba 535 Pfam PF08676 MutL C terminal dimerisation domain 335 470 9.5E-27 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Theos_0521 e01973de1713da7dd501324c9768dbba 535 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 196 299 2.0E-14 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Theos_0521 e01973de1713da7dd501324c9768dbba 535 SUPERFAMILY SSF118116 334 512 2.88E-35 T 14-10-2018 IPR037198 MutL, C-terminal domain superfamily Theos_0521 e01973de1713da7dd501324c9768dbba 535 Gene3D G3DSA:2.30.42.20 339 512 5.0E-42 T 14-10-2018 Theos_0521 e01973de1713da7dd501324c9768dbba 535 Gene3D G3DSA:3.30.230.10 198 315 7.7E-10 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_0521 e01973de1713da7dd501324c9768dbba 535 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 23 114 6.1E-9 T 14-10-2018 Theos_0521 e01973de1713da7dd501324c9768dbba 535 Gene3D G3DSA:3.30.1370.100 380 467 5.0E-42 T 14-10-2018 Theos_0521 e01973de1713da7dd501324c9768dbba 535 Gene3D G3DSA:3.30.565.10 1 181 2.1E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0521 e01973de1713da7dd501324c9768dbba 535 SMART SM01340 192 309 2.1E-21 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Theos_0521 e01973de1713da7dd501324c9768dbba 535 SUPERFAMILY SSF54211 181 303 3.22E-14 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_0521 e01973de1713da7dd501324c9768dbba 535 SUPERFAMILY SSF55874 2 185 1.14E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0521 e01973de1713da7dd501324c9768dbba 535 SMART SM00853 338 470 9.7E-30 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Theos_0786 ce009d27584a90063931378c7da4c8e8 105 SUPERFAMILY SSF103007 7 96 3.01E-22 T 14-10-2018 IPR036746 TT1725-like superfamily Theos_0786 ce009d27584a90063931378c7da4c8e8 105 Gene3D G3DSA:3.30.70.1120 4 105 1.7E-38 T 14-10-2018 IPR036746 TT1725-like superfamily Theos_0786 ce009d27584a90063931378c7da4c8e8 105 Pfam PF04456 Protein of unknown function (DUF503) 10 90 2.5E-19 T 14-10-2018 IPR007546 Protein of unknown function DUF503 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 9 301 73.228 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 Gene3D G3DSA:3.40.50.1370 137 287 2.6E-108 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 1.2E-21 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 1.2E-21 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 1.2E-21 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 1.2E-21 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 10 300 4.8E-106 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 147 1.2E-41 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 217 227 4.6E-23 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 4.6E-23 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 4.6E-23 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 4.6E-23 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 4.6E-23 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 Gene3D G3DSA:3.40.50.1370 21 296 2.6E-108 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 298 3.6E-46 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Theos_1220 fcd1dd55de422bddbb1a2a90130fe0c0 301 SUPERFAMILY SSF53671 9 300 4.32E-90 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 SUPERFAMILY SSF51735 194 331 3.03E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 SMART SM00881 202 300 4.6E-27 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 SUPERFAMILY SSF52210 471 599 3.01E-10 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 346 436 3.2E-29 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 SUPERFAMILY SSF52210 326 466 1.57E-30 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 Pfam PF13302 Acetyltransferase (GNAT) domain 27 161 1.5E-7 T 14-10-2018 IPR000182 GNAT domain Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 Gene3D G3DSA:3.40.50.261 501 604 3.0E-9 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 Pfam PF13380 CoA binding domain 208 329 2.5E-17 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 SUPERFAMILY SSF55729 25 166 2.23E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 Gene3D G3DSA:3.40.630.30 17 197 3.7E-38 T 14-10-2018 Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 Gene3D G3DSA:3.40.50.261 325 467 5.7E-36 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Theos_0030 9dd7628a21087fee10c93b8c576120f2 740 Gene3D G3DSA:3.40.50.720 198 323 5.0E-32 T 14-10-2018 Theos_1004 ee50105df8f4989fe22a3603b51e98c5 171 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 161 1.9E-28 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ Theos_1157 9d51e73fe0833e23aafba363c55bef4e 288 SUPERFAMILY SSF160240 204 283 1.2E-23 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Theos_1157 9d51e73fe0833e23aafba363c55bef4e 288 Pfam PF01545 Cation efflux family 7 200 3.2E-42 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Theos_1157 9d51e73fe0833e23aafba363c55bef4e 288 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 3 284 8.7E-71 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Theos_1157 9d51e73fe0833e23aafba363c55bef4e 288 Gene3D G3DSA:1.20.1510.10 2 199 5.2E-54 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Theos_1157 9d51e73fe0833e23aafba363c55bef4e 288 SUPERFAMILY SSF161111 2 202 2.48E-53 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Theos_1157 9d51e73fe0833e23aafba363c55bef4e 288 Gene3D G3DSA:3.30.70.1350 200 288 1.2E-33 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Theos_1157 9d51e73fe0833e23aafba363c55bef4e 288 Pfam PF16916 Dimerisation domain of Zinc Transporter 206 283 4.4E-25 T 14-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Pfam PF05188 MutS domain II 129 184 5.6E-9 T 14-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 10 790 21.977 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 654 670 - T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Gene3D G3DSA:1.10.1420.10 255 534 4.6E-99 T 14-10-2018 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Gene3D G3DSA:3.40.1170.10 1 123 8.0E-46 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 SMART SM00534 573 757 6.2E-114 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Gene3D G3DSA:1.10.1420.10 372 507 4.6E-99 T 14-10-2018 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Gene3D G3DSA:3.40.50.300 539 760 8.9E-97 T 14-10-2018 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Pfam PF05190 MutS family domain IV 400 489 2.9E-25 T 14-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Pfam PF05192 MutS domain III 252 531 5.7E-40 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 SUPERFAMILY SSF53150 123 262 2.22E-27 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 SUPERFAMILY SSF55271 9 117 1.7E-35 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 PIRSF PIRSF037677 9 187 1.4E-24 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 PIRSF PIRSF037677 213 363 9.5E-21 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 PIRSF PIRSF037677 388 762 2.2E-91 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 SUPERFAMILY SSF52540 539 757 3.4E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 SMART SM00533 264 561 3.4E-95 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 11 795 0.0 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 SUPERFAMILY SSF48334 266 537 7.19E-76 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Pfam PF00488 MutS domain V 577 758 9.3E-79 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Pfam PF01624 MutS domain I 12 121 1.4E-34 T 14-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Theos_0520 7712bcadefa7cd899a026f69eda9a374 804 Gene3D G3DSA:3.30.420.110 128 245 3.1E-46 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Theos_1039 5078b7e769b758ab90914be8893efb0a 167 Gene3D G3DSA:1.20.120.700 10 64 1.9E-6 T 14-10-2018 Theos_1039 5078b7e769b758ab90914be8893efb0a 167 Gene3D G3DSA:1.10.4070.10 65 120 1.9E-6 T 14-10-2018 Theos_1039 5078b7e769b758ab90914be8893efb0a 167 SUPERFAMILY SSF89155 4 159 1.15E-16 T 14-10-2018 IPR036411 TorD-like superfamily Theos_1039 5078b7e769b758ab90914be8893efb0a 167 Pfam PF02613 Nitrate reductase delta subunit 37 119 4.1E-5 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Gene3D G3DSA:3.30.70.3400 48 258 1.4E-81 T 14-10-2018 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Pfam PF02355 Protein export membrane protein 256 427 9.0E-16 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Pfam PF02355 Protein export membrane protein 549 724 1.4E-63 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 SUPERFAMILY SSF82866 548 727 1.7E-40 T 14-10-2018 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 434 38.344 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 35 422 3.8E-126 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 SUPERFAMILY SSF82866 231 426 2.75E-33 T 14-10-2018 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Gene3D G3DSA:3.30.70.2040 477 554 3.2E-44 T 14-10-2018 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Gene3D G3DSA:3.30.1360.200 112 252 1.4E-81 T 14-10-2018 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 470 715 8.8E-74 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Gene3D G3DSA:1.20.1640.10 555 726 1.2E-7 T 14-10-2018 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 442 727 27.545 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 PRINTS PR01755 Bacterial translocase SecF protein signature 584 598 6.1E-29 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 PRINTS PR01755 Bacterial translocase SecF protein signature 632 650 6.1E-29 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 PRINTS PR01755 Bacterial translocase SecF protein signature 469 484 6.1E-29 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 PRINTS PR01755 Bacterial translocase SecF protein signature 664 679 6.1E-29 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Pfam PF07549 SecD/SecF GG Motif 32 50 0.0039 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 Pfam PF07549 SecD/SecF GG Motif 466 489 3.9E-7 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 184 414 3.0E-65 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Theos_1172 bdb5d69d25a8fdfc9c35d57a46873b82 735 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 549 713 8.4E-56 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 Gene3D G3DSA:3.40.50.880 1 189 4.1E-61 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 2.6E-13 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 2.6E-13 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 2.6E-13 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 1.0E-6 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 1.0E-6 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 SUPERFAMILY SSF52317 1 189 4.58E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00097 Anthranilate synthase component II signature 166 179 7.8E-36 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00097 Anthranilate synthase component II signature 75 86 7.8E-36 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00097 Anthranilate synthase component II signature 100 108 7.8E-36 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00097 Anthranilate synthase component II signature 120 132 7.8E-36 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00097 Anthranilate synthase component II signature 3 17 7.8E-36 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 PRINTS PR00097 Anthranilate synthase component II signature 48 57 7.8E-36 T 14-10-2018 Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 Pfam PF00117 Glutamine amidotransferase class-I 5 187 2.8E-50 T 14-10-2018 IPR017926 Glutamine amidotransferase Theos_1992 a4bc124d89f44cde3431d4e8e626ae11 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 188 1.6E-71 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Theos_2136 8e01dc290c2aca2d73ff5c40352892a9 158 Pfam PF14326 Domain of unknown function (DUF4384) 48 118 3.4E-7 T 14-10-2018 IPR025493 Domain of unknown function DUF4384 Theos_2214 7ea86e78f7eb20d89dd50a9f79b9380b 625 Gene3D G3DSA:3.10.180.10 417 603 3.2E-35 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_2214 7ea86e78f7eb20d89dd50a9f79b9380b 625 Pfam PF01261 Xylose isomerase-like TIM barrel 20 217 1.8E-34 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Theos_2214 7ea86e78f7eb20d89dd50a9f79b9380b 625 SUPERFAMILY SSF54593 304 600 3.31E-46 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_2214 7ea86e78f7eb20d89dd50a9f79b9380b 625 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 284 397 9.4E-11 T 14-10-2018 Theos_2214 7ea86e78f7eb20d89dd50a9f79b9380b 625 Gene3D G3DSA:3.20.20.150 1 272 1.9E-73 T 14-10-2018 Theos_2214 7ea86e78f7eb20d89dd50a9f79b9380b 625 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 420 534 2.3E-4 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Theos_2214 7ea86e78f7eb20d89dd50a9f79b9380b 625 SUPERFAMILY SSF51658 3 272 5.67E-72 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily Theos_2214 7ea86e78f7eb20d89dd50a9f79b9380b 625 Gene3D G3DSA:3.10.180.10 276 405 1.8E-15 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 Gene3D G3DSA:2.60.40.420 15 138 5.5E-26 T 14-10-2018 IPR008972 Cupredoxin Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 357 440 1.2E-5 T 14-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 SUPERFAMILY SSF49503 351 442 2.78E-19 T 14-10-2018 IPR008972 Cupredoxin Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 PRINTS PR00695 Copper containing nitrite reductase signature 102 117 4.2E-12 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 PRINTS PR00695 Copper containing nitrite reductase signature 45 61 4.2E-12 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 PRINTS PR00695 Copper containing nitrite reductase signature 19 37 4.2E-12 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 PRINTS PR00695 Copper containing nitrite reductase signature 121 137 4.2E-12 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 SUPERFAMILY SSF49503 9 141 1.13E-24 T 14-10-2018 IPR008972 Cupredoxin Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 Gene3D G3DSA:2.60.40.420 151 293 3.4E-34 T 14-10-2018 IPR008972 Cupredoxin Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 Pfam PF07732 Multicopper oxidase 36 140 1.8E-9 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 SUPERFAMILY SSF49503 153 286 2.97E-23 T 14-10-2018 IPR008972 Cupredoxin Theos_1053 edcfc7918bae925ee2b0d773a344e1de 452 Gene3D G3DSA:2.60.40.420 341 440 1.1E-20 T 14-10-2018 IPR008972 Cupredoxin Theos_1045 3b5b93acdc1ef109e7f70553d4b94473 74 Pfam PF04023 FeoA domain 3 71 1.2E-14 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Theos_1045 3b5b93acdc1ef109e7f70553d4b94473 74 SUPERFAMILY SSF50037 4 72 2.08E-15 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal Theos_1045 3b5b93acdc1ef109e7f70553d4b94473 74 SMART SM00899 2 71 1.8E-16 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Theos_1045 3b5b93acdc1ef109e7f70553d4b94473 74 Gene3D G3DSA:2.30.30.90 1 74 1.9E-19 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain Theos_1556 d107eb3b94c3c710f7cc5aaf86eed11b 369 Gene3D G3DSA:3.20.20.120 117 346 7.8E-144 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Theos_1556 d107eb3b94c3c710f7cc5aaf86eed11b 369 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 41.02 T 14-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 Theos_1556 d107eb3b94c3c710f7cc5aaf86eed11b 369 Gene3D G3DSA:3.30.390.10 7 350 7.8E-144 T 14-10-2018 IPR029017 Enolase-like, N-terminal Theos_1556 d107eb3b94c3c710f7cc5aaf86eed11b 369 SUPERFAMILY SSF51604 113 363 5.5E-66 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Theos_1556 d107eb3b94c3c710f7cc5aaf86eed11b 369 SUPERFAMILY SSF54826 2 125 1.77E-32 T 14-10-2018 Theos_1556 d107eb3b94c3c710f7cc5aaf86eed11b 369 Pfam PF13378 Enolase C-terminal domain-like 147 352 4.6E-44 T 14-10-2018 IPR029065 Enolase C-terminal domain-like Theos_1556 d107eb3b94c3c710f7cc5aaf86eed11b 369 SMART SM00922 142 234 3.8E-22 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Theos_1556 d107eb3b94c3c710f7cc5aaf86eed11b 369 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 12 330 1.0E-98 T 14-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 Theos_1556 d107eb3b94c3c710f7cc5aaf86eed11b 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 124 3.7E-11 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Theos_1729 7d89cb917bc67c9b32eaf845132d74da 237 Pfam PF00230 Major intrinsic protein 5 229 1.0E-34 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Theos_1729 7d89cb917bc67c9b32eaf845132d74da 237 SUPERFAMILY SSF81338 6 230 2.35E-47 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Theos_1729 7d89cb917bc67c9b32eaf845132d74da 237 Gene3D G3DSA:1.20.1080.10 3 232 3.0E-53 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Theos_1729 7d89cb917bc67c9b32eaf845132d74da 237 PRINTS PR00783 Major intrinsic protein family signature 49 73 6.9E-28 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Theos_1729 7d89cb917bc67c9b32eaf845132d74da 237 PRINTS PR00783 Major intrinsic protein family signature 213 233 6.9E-28 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Theos_1729 7d89cb917bc67c9b32eaf845132d74da 237 PRINTS PR00783 Major intrinsic protein family signature 169 191 6.9E-28 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Theos_1729 7d89cb917bc67c9b32eaf845132d74da 237 PRINTS PR00783 Major intrinsic protein family signature 6 25 6.9E-28 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Theos_1729 7d89cb917bc67c9b32eaf845132d74da 237 PRINTS PR00783 Major intrinsic protein family signature 86 105 6.9E-28 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Theos_1729 7d89cb917bc67c9b32eaf845132d74da 237 ProSitePatterns PS00221 MIP family signature. 67 75 - T 14-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 Theos_0982 af6e2722c2e725a6fa0fcccc43f6a505 134 SMART SM00347 22 120 1.7E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_0982 af6e2722c2e725a6fa0fcccc43f6a505 134 Gene3D G3DSA:1.10.10.10 2 134 3.3E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0982 af6e2722c2e725a6fa0fcccc43f6a505 134 Pfam PF12802 MarR family 28 84 2.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_0982 af6e2722c2e725a6fa0fcccc43f6a505 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 1.5E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_0982 af6e2722c2e725a6fa0fcccc43f6a505 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 76 1.5E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_0982 af6e2722c2e725a6fa0fcccc43f6a505 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 44 60 1.5E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_0982 af6e2722c2e725a6fa0fcccc43f6a505 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 1.5E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_0982 af6e2722c2e725a6fa0fcccc43f6a505 134 SUPERFAMILY SSF46785 4 132 3.45E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1799 5a59b7312d2281a07dc4220c9fe0447a 232 SMART SM00422 127 196 4.8E-26 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Theos_1799 5a59b7312d2281a07dc4220c9fe0447a 232 SMART SM00422 8 77 4.8E-26 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Theos_1799 5a59b7312d2281a07dc4220c9fe0447a 232 Gene3D G3DSA:1.10.1660.10 1 110 4.1E-23 T 14-10-2018 Theos_1799 5a59b7312d2281a07dc4220c9fe0447a 232 SUPERFAMILY SSF46955 127 214 5.95E-19 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_1799 5a59b7312d2281a07dc4220c9fe0447a 232 SUPERFAMILY SSF46955 8 102 1.56E-19 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_1799 5a59b7312d2281a07dc4220c9fe0447a 232 Gene3D G3DSA:1.10.1660.10 118 227 2.1E-22 T 14-10-2018 Theos_1799 5a59b7312d2281a07dc4220c9fe0447a 232 Pfam PF13411 MerR HTH family regulatory protein 8 75 3.2E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Theos_1799 5a59b7312d2281a07dc4220c9fe0447a 232 Pfam PF13411 MerR HTH family regulatory protein 127 194 3.2E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Theos_0583 c329e9318c1146fd5dd302f03d27e55b 343 Gene3D G3DSA:3.40.50.2300 67 313 3.0E-71 T 14-10-2018 Theos_0583 c329e9318c1146fd5dd302f03d27e55b 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 5.4E-20 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Theos_0583 c329e9318c1146fd5dd302f03d27e55b 343 Gene3D G3DSA:1.10.260.40 1 61 1.6E-24 T 14-10-2018 Theos_0583 c329e9318c1146fd5dd302f03d27e55b 343 Pfam PF13377 Periplasmic binding protein-like domain 193 333 4.0E-23 T 14-10-2018 Theos_0583 c329e9318c1146fd5dd302f03d27e55b 343 SUPERFAMILY SSF53822 64 336 6.42E-43 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_0583 c329e9318c1146fd5dd302f03d27e55b 343 Gene3D G3DSA:3.40.50.2300 160 293 3.0E-71 T 14-10-2018 Theos_0583 c329e9318c1146fd5dd302f03d27e55b 343 SMART SM00354 4 74 1.1E-27 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Theos_0583 c329e9318c1146fd5dd302f03d27e55b 343 SUPERFAMILY SSF47413 3 62 1.63E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Theos_0583 c329e9318c1146fd5dd302f03d27e55b 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 14-10-2018 Theos_0399 0d475f835c112531f14e1b29b8c2af3c 336 SUPERFAMILY SSF161098 94 319 1.46E-18 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0399 0d475f835c112531f14e1b29b8c2af3c 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 335 8.4E-45 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2028 f488ec6f4fe5e9971ec422ddc29aff18 125 SMART SM00316 4 74 1.4E-21 T 14-10-2018 IPR022967 RNA-binding domain, S1 Theos_2028 f488ec6f4fe5e9971ec422ddc29aff18 125 Gene3D G3DSA:2.40.50.140 3 77 3.7E-26 T 14-10-2018 Theos_2028 f488ec6f4fe5e9971ec422ddc29aff18 125 SUPERFAMILY SSF50249 4 80 3.3E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_2028 f488ec6f4fe5e9971ec422ddc29aff18 125 Pfam PF00575 S1 RNA binding domain 3 74 5.1E-16 T 14-10-2018 IPR003029 S1 domain GO:0003676 Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.8E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.8E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.8E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 4 242 3.4E-100 T 14-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 242 3.0E-68 T 14-10-2018 Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 183 4.8E-5 T 14-10-2018 Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 Gene3D G3DSA:3.40.50.720 1 244 4.0E-86 T 14-10-2018 Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 SUPERFAMILY SSF51735 2 242 1.64E-85 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.3E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.3E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.3E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.3E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.3E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0671 e2330a490445faaa3e7a00fc4d5528e5 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.3E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0734 3073dc8ce7b9f0b89dd8b75e792db45f 363 Gene3D G3DSA:3.40.50.20 2 96 7.2E-33 T 14-10-2018 Theos_0734 3073dc8ce7b9f0b89dd8b75e792db45f 363 Pfam PF02222 ATP-grasp domain 106 275 2.3E-54 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type Theos_0734 3073dc8ce7b9f0b89dd8b75e792db45f 363 Gene3D G3DSA:3.30.1490.20 97 175 4.7E-27 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Theos_0734 3073dc8ce7b9f0b89dd8b75e792db45f 363 Gene3D G3DSA:3.30.470.20 176 362 1.5E-76 T 14-10-2018 Theos_0734 3073dc8ce7b9f0b89dd8b75e792db45f 363 SUPERFAMILY SSF56059 97 295 7.07E-67 T 14-10-2018 Theos_0734 3073dc8ce7b9f0b89dd8b75e792db45f 363 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 347 42.939 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Theos_0734 3073dc8ce7b9f0b89dd8b75e792db45f 363 SUPERFAMILY SSF52440 2 94 2.01E-22 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Theos_0734 3073dc8ce7b9f0b89dd8b75e792db45f 363 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 3 351 1.9E-116 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Theos_0734 3073dc8ce7b9f0b89dd8b75e792db45f 363 SUPERFAMILY SSF51246 300 358 1.18E-16 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 115 2.8E-12 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 Gene3D G3DSA:3.40.50.720 5 290 7.5E-117 T 14-10-2018 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 306 131.875 T 14-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 126 272 4.2E-57 T 14-10-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 SMART SM00859 5 118 1.0E-11 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 3 297 3.3E-136 T 14-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 SUPERFAMILY SSF55347 126 272 2.35E-56 T 14-10-2018 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 Gene3D G3DSA:3.30.360.10 126 272 7.5E-117 T 14-10-2018 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 PIRSF PIRSF015689 1 303 5.0E-124 T 14-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 Theos_2474 b83dfdb883e06af3810fe7274a8d9fee 306 SUPERFAMILY SSF51735 1 150 1.12E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0349 ba21eae71861282c0736c510f409cb18 254 SMART SM00332 1 251 4.5E-16 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Theos_0349 ba21eae71861282c0736c510f409cb18 254 Pfam PF13672 Protein phosphatase 2C 16 226 7.0E-14 T 14-10-2018 Theos_0349 ba21eae71861282c0736c510f409cb18 254 Gene3D G3DSA:3.60.40.10 4 254 1.5E-53 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Theos_0349 ba21eae71861282c0736c510f409cb18 254 SUPERFAMILY SSF81606 13 253 7.32E-51 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Theos_0349 ba21eae71861282c0736c510f409cb18 254 SMART SM00331 15 253 1.2E-20 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Theos_0018 7aa278ddc3a5c8071fe2b2cd238e839d 156 SUPERFAMILY SSF55811 6 141 2.44E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Theos_0018 7aa278ddc3a5c8071fe2b2cd238e839d 156 Gene3D G3DSA:3.90.79.10 1 144 2.8E-38 T 14-10-2018 Theos_0018 7aa278ddc3a5c8071fe2b2cd238e839d 156 Pfam PF00293 NUDIX domain 2 108 2.2E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Theos_0018 7aa278ddc3a5c8071fe2b2cd238e839d 156 ProSitePatterns PS00893 Nudix box signature. 31 52 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Theos_2047 95e1256bde8c8777815bc6e00c048c6a 267 Pfam PF02517 CAAX protease self-immunity 125 225 1.6E-14 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 Theos_0862 7478ade776424b7b72985d0de1ad3274 186 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 127 182 4.4E-31 T 14-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal Theos_0862 7478ade776424b7b72985d0de1ad3274 186 SUPERFAMILY SSF69754 5 106 1.57E-27 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like Theos_0862 7478ade776424b7b72985d0de1ad3274 186 Gene3D G3DSA:3.30.160.100 1 105 3.7E-39 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like Theos_0862 7478ade776424b7b72985d0de1ad3274 186 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 5 99 1.0E-24 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 Theos_0862 7478ade776424b7b72985d0de1ad3274 186 Gene3D G3DSA:3.30.505.50 140 186 4.2E-27 T 14-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily Theos_0862 7478ade776424b7b72985d0de1ad3274 186 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 98 8.4E-26 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 Theos_0862 7478ade776424b7b72985d0de1ad3274 186 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 186 24.131 T 14-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid Theos_1082 7887f6064d7fb9f7291125e9291639db 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1082 7887f6064d7fb9f7291125e9291639db 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 4.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1082 7887f6064d7fb9f7291125e9291639db 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 4.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1082 7887f6064d7fb9f7291125e9291639db 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 237 3.6E-67 T 14-10-2018 Theos_1082 7887f6064d7fb9f7291125e9291639db 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_1082 7887f6064d7fb9f7291125e9291639db 245 Gene3D G3DSA:3.40.50.720 1 245 2.1E-87 T 14-10-2018 Theos_1082 7887f6064d7fb9f7291125e9291639db 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1082 7887f6064d7fb9f7291125e9291639db 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1082 7887f6064d7fb9f7291125e9291639db 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1082 7887f6064d7fb9f7291125e9291639db 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1082 7887f6064d7fb9f7291125e9291639db 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1082 7887f6064d7fb9f7291125e9291639db 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 4.4E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1082 7887f6064d7fb9f7291125e9291639db 245 SUPERFAMILY SSF51735 5 240 8.16E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1082 7887f6064d7fb9f7291125e9291639db 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 179 3.0E-5 T 14-10-2018 Theos_1730 8fba30934af351afa63af28b50787566 307 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 84 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Theos_1730 8fba30934af351afa63af28b50787566 307 PIRSF PIRSF001359 1 307 2.6E-112 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Theos_1730 8fba30934af351afa63af28b50787566 307 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 2 306 2.5E-102 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Theos_1730 8fba30934af351afa63af28b50787566 307 Pfam PF01116 Fructose-bisphosphate aldolase class-II 7 306 4.6E-102 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Theos_1730 8fba30934af351afa63af28b50787566 307 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 307 6.8E-117 T 14-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Theos_1730 8fba30934af351afa63af28b50787566 307 Gene3D G3DSA:3.20.20.70 2 307 2.4E-125 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1730 8fba30934af351afa63af28b50787566 307 SUPERFAMILY SSF51569 4 307 6.89E-106 T 14-10-2018 Theos_1551 0b67ae983bf79449102f4f8ff906aadd 393 Gene3D G3DSA:3.20.20.370 22 208 1.6E-37 T 14-10-2018 Theos_1551 0b67ae983bf79449102f4f8ff906aadd 393 Pfam PF01522 Polysaccharide deacetylase 31 100 3.4E-18 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 Theos_1551 0b67ae983bf79449102f4f8ff906aadd 393 SUPERFAMILY SSF88713 26 208 6.67E-43 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 18 421 1.4E-172 T 14-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 175 190 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 350 361 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 Gene3D G3DSA:3.10.20.600 240 334 8.5E-36 T 14-10-2018 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 339 421 5.8E-26 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 SUPERFAMILY SSF142984 249 331 7.32E-24 T 14-10-2018 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 SUPERFAMILY SSF140490 334 431 2.22E-32 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 Gene3D G3DSA:1.20.1440.230 335 437 2.1E-35 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 57 226 1.0E-50 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 Pfam PF10531 SLBB domain 251 297 2.2E-12 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 Gene3D G3DSA:3.40.50.11540 62 239 4.6E-84 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 SUPERFAMILY SSF142019 15 247 5.75E-91 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0711 b028047571181bbbc685fa774e51a4aa 437 SMART SM00928 337 383 1.7E-19 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_2157 fea62e357e2c9d9196f952a9617bd6d0 309 SMART SM00331 10 236 1.4E-39 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Theos_2157 fea62e357e2c9d9196f952a9617bd6d0 309 SMART SM00332 1 234 3.3E-37 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Theos_2157 fea62e357e2c9d9196f952a9617bd6d0 309 SUPERFAMILY SSF81606 7 236 1.83E-66 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Theos_2157 fea62e357e2c9d9196f952a9617bd6d0 309 Gene3D G3DSA:3.60.40.10 4 238 5.8E-70 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Theos_2157 fea62e357e2c9d9196f952a9617bd6d0 309 Pfam PF13672 Protein phosphatase 2C 18 217 3.5E-19 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 SUPERFAMILY SSF81665 2 806 5.1E-96 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 51 6.6E-18 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 Pfam PF00122 E1-E2 ATPase 99 279 3.1E-52 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 Gene3D G3DSA:3.40.50.1000 450 513 1.6E-11 T 14-10-2018 IPR023214 HAD superfamily Theos_1506 668292711d25dc7cd5097c322bc98072 810 Pfam PF00702 haloacid dehalogenase-like hydrolase 296 559 1.3E-25 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 545 561 8.6E-21 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 577 602 8.6E-21 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 517 533 8.6E-21 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 417 435 8.6E-21 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 SUPERFAMILY SSF56784 297 661 6.79E-60 T 14-10-2018 IPR036412 HAD-like superfamily Theos_1506 668292711d25dc7cd5097c322bc98072 810 Gene3D G3DSA:3.40.1110.10 323 449 4.5E-19 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 Gene3D G3DSA:1.20.1110.10 193 314 1.2E-33 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 Gene3D G3DSA:1.20.1110.10 557 808 2.1E-45 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 SUPERFAMILY SSF81653 102 198 1.05E-27 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 SMART SM00831 2 57 1.5E-13 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 Gene3D G3DSA:2.60.120.1500 104 192 4.8E-27 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 Pfam PF00689 Cation transporting ATPase, C-terminus 641 800 4.7E-29 T 14-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 71 319 2.4E-45 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 363 495 1.4E-20 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 516 629 4.1E-35 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 Gene3D G3DSA:1.20.1110.10 35 103 1.8E-9 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 471 481 4.6E-39 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 149 163 4.6E-39 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 569 581 4.6E-39 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 449 460 4.6E-39 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 564 4.6E-39 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 299 313 4.6E-39 T 14-10-2018 Theos_1506 668292711d25dc7cd5097c322bc98072 810 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 301 307 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Theos_1506 668292711d25dc7cd5097c322bc98072 810 SUPERFAMILY SSF81660 306 451 3.05E-22 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Theos_0717 d1521ea5e314ea36109b950363d08965 274 SUPERFAMILY SSF53335 14 267 2.41E-56 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0717 d1521ea5e314ea36109b950363d08965 274 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 18 264 1.2E-68 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Theos_0717 d1521ea5e314ea36109b950363d08965 274 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 48 75 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 Theos_0717 d1521ea5e314ea36109b950363d08965 274 Gene3D G3DSA:3.40.50.150 3 200 6.2E-65 T 14-10-2018 Theos_0717 d1521ea5e314ea36109b950363d08965 274 SMART SM00650 33 199 3.1E-64 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 Theos_0717 d1521ea5e314ea36109b950363d08965 274 Gene3D G3DSA:1.10.8.100 202 269 1.6E-21 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 Theos_0717 d1521ea5e314ea36109b950363d08965 274 Pfam PF00398 Ribosomal RNA adenine dimethylase 18 254 5.1E-40 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Theos_0717 d1521ea5e314ea36109b950363d08965 274 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 17 266 47.791 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Theos_0153 57f2c90a3703307eeea22b63676dbf1e 229 SUPERFAMILY SSF51161 4 160 1.94E-47 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Theos_0153 57f2c90a3703307eeea22b63676dbf1e 229 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 45 1.3E-5 T 14-10-2018 IPR001451 Hexapeptide repeat Theos_0153 57f2c90a3703307eeea22b63676dbf1e 229 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 5.4E-9 T 14-10-2018 IPR001451 Hexapeptide repeat Theos_0153 57f2c90a3703307eeea22b63676dbf1e 229 Gene3D G3DSA:2.160.10.10 3 165 7.1E-58 T 14-10-2018 Theos_0795 8e5894ec244fe54bf5191c37d11e526e 2676 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 2353 2655 3.6E-21 T 14-10-2018 IPR007452 Translocation and assembly module TamB Theos_2171 099d4f62a0f6b8155f3f18a657d3e47c 194 Gene3D G3DSA:1.10.357.10 57 188 3.8E-15 T 14-10-2018 Theos_2171 099d4f62a0f6b8155f3f18a657d3e47c 194 SUPERFAMILY SSF48498 77 183 4.79E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Theos_2171 099d4f62a0f6b8155f3f18a657d3e47c 194 Gene3D G3DSA:1.10.10.60 5 56 1.8E-16 T 14-10-2018 Theos_2171 099d4f62a0f6b8155f3f18a657d3e47c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 5.8E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_2171 099d4f62a0f6b8155f3f18a657d3e47c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 5.8E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_2171 099d4f62a0f6b8155f3f18a657d3e47c 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.0E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_2171 099d4f62a0f6b8155f3f18a657d3e47c 194 SUPERFAMILY SSF46689 8 63 2.59E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_2202 0fd4621945415fce6089130ddf939500 673 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 184 351 3.7E-20 T 14-10-2018 IPR004477 ComEC/Rec2-related protein Theos_2202 0fd4621945415fce6089130ddf939500 673 SUPERFAMILY SSF56281 438 669 3.77E-37 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_2202 0fd4621945415fce6089130ddf939500 673 Pfam PF03772 Competence protein 164 410 4.6E-43 T 14-10-2018 IPR004477 ComEC/Rec2-related protein Theos_2202 0fd4621945415fce6089130ddf939500 673 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 102 663 5.1E-60 T 14-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 Theos_2202 0fd4621945415fce6089130ddf939500 673 Gene3D G3DSA:3.60.15.10 442 671 6.4E-53 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_2202 0fd4621945415fce6089130ddf939500 673 SMART SM00849 450 635 8.1E-5 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_2202 0fd4621945415fce6089130ddf939500 673 Pfam PF00753 Metallo-beta-lactamase superfamily 447 631 2.5E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0208 af1d83281301cebaded6510bbe4e1020 89 Pfam PF00462 Glutaredoxin 8 56 7.8E-9 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Theos_0208 af1d83281301cebaded6510bbe4e1020 89 Gene3D G3DSA:3.40.30.10 7 87 3.1E-12 T 14-10-2018 Theos_0208 af1d83281301cebaded6510bbe4e1020 89 SUPERFAMILY SSF52833 7 84 1.51E-11 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0294 c6f65ee1882fd76b0bf0162478914f8f 157 ProSitePatterns PS00585 Ribosomal protein S5 signature. 23 55 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site Theos_0294 c6f65ee1882fd76b0bf0162478914f8f 157 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 3 153 7.0E-62 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Theos_0294 c6f65ee1882fd76b0bf0162478914f8f 157 Pfam PF00333 Ribosomal protein S5, N-terminal domain 6 70 1.5E-24 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 Theos_0294 c6f65ee1882fd76b0bf0162478914f8f 157 Gene3D G3DSA:3.30.160.20 1 68 1.2E-28 T 14-10-2018 Theos_0294 c6f65ee1882fd76b0bf0162478914f8f 157 Gene3D G3DSA:3.30.230.10 69 157 4.0E-34 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_0294 c6f65ee1882fd76b0bf0162478914f8f 157 SUPERFAMILY SSF54211 74 152 1.97E-24 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_0294 c6f65ee1882fd76b0bf0162478914f8f 157 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 157 32.399 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Theos_0294 c6f65ee1882fd76b0bf0162478914f8f 157 SUPERFAMILY SSF54768 4 71 4.19E-21 T 14-10-2018 Theos_0294 c6f65ee1882fd76b0bf0162478914f8f 157 Pfam PF03719 Ribosomal protein S5, C-terminal domain 82 152 1.9E-29 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 Theos_0673 2a6f887733f6741ea92cda6059ef3f0d 322 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 319 64.929 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Theos_0673 2a6f887733f6741ea92cda6059ef3f0d 322 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 319 1.9E-113 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Theos_0673 2a6f887733f6741ea92cda6059ef3f0d 322 Gene3D G3DSA:3.40.47.10 1 171 4.8E-70 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0673 2a6f887733f6741ea92cda6059ef3f0d 322 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 230 319 8.4E-40 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Theos_0673 2a6f887733f6741ea92cda6059ef3f0d 322 Gene3D G3DSA:3.40.47.10 172 322 3.8E-58 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0673 2a6f887733f6741ea92cda6059ef3f0d 322 SUPERFAMILY SSF53901 3 319 2.36E-71 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0673 2a6f887733f6741ea92cda6059ef3f0d 322 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 104 182 3.1E-26 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 Pfam PF00164 Ribosomal protein S12/S23 15 126 5.0E-43 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 PIRSF PIRSF002133 4 127 2.9E-55 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 SUPERFAMILY SSF50249 5 127 1.03E-52 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 PRINTS PR01034 Ribosomal protein S12 signature 113 125 2.7E-57 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 PRINTS PR01034 Ribosomal protein S12 signature 61 80 2.7E-57 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 PRINTS PR01034 Ribosomal protein S12 signature 97 113 2.7E-57 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 PRINTS PR01034 Ribosomal protein S12 signature 30 45 2.7E-57 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 PRINTS PR01034 Ribosomal protein S12 signature 45 60 2.7E-57 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 PRINTS PR01034 Ribosomal protein S12 signature 80 97 2.7E-57 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 46 53 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 Gene3D G3DSA:2.40.50.140 1 135 5.9E-66 T 14-10-2018 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 4 126 39.842 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0272 fc68344f26f5c4a51b337f7843dfddd4 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 5 126 2.7E-67 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0737 62a2119a602a02c993ac1b508b85c38c 100 SUPERFAMILY SSF54913 1 98 3.61E-24 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Theos_0737 62a2119a602a02c993ac1b508b85c38c 100 Gene3D G3DSA:3.30.70.120 2 100 9.0E-33 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Theos_1238 b7ebb50310e7ee67c6a230c655475d40 230 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 2.7E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1238 b7ebb50310e7ee67c6a230c655475d40 230 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 26 2.4E-6 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1238 b7ebb50310e7ee67c6a230c655475d40 230 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1238 b7ebb50310e7ee67c6a230c655475d40 230 SUPERFAMILY SSF54523 6 64 4.47E-6 T 14-10-2018 Theos_1328 c19922187793eb92a445318d431903dc 257 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 3 226 40.442 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1328 c19922187793eb92a445318d431903dc 257 Pfam PF00318 Ribosomal protein S2 10 224 5.0E-91 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1328 c19922187793eb92a445318d431903dc 257 PRINTS PR00395 Ribosomal protein S2 signature 7 25 3.3E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1328 c19922187793eb92a445318d431903dc 257 PRINTS PR00395 Ribosomal protein S2 signature 38 47 3.3E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1328 c19922187793eb92a445318d431903dc 257 PRINTS PR00395 Ribosomal protein S2 signature 159 176 3.3E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1328 c19922187793eb92a445318d431903dc 257 PRINTS PR00395 Ribosomal protein S2 signature 176 187 3.3E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1328 c19922187793eb92a445318d431903dc 257 PRINTS PR00395 Ribosomal protein S2 signature 88 105 3.3E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1328 c19922187793eb92a445318d431903dc 257 PRINTS PR00395 Ribosomal protein S2 signature 197 211 3.3E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1328 c19922187793eb92a445318d431903dc 257 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 5 226 1.2E-95 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1328 c19922187793eb92a445318d431903dc 257 Gene3D G3DSA:1.10.287.610 98 153 3.2E-94 T 14-10-2018 Theos_1328 c19922187793eb92a445318d431903dc 257 SUPERFAMILY SSF52313 7 230 1.44E-88 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily Theos_1328 c19922187793eb92a445318d431903dc 257 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 7 18 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 Theos_1328 c19922187793eb92a445318d431903dc 257 Gene3D G3DSA:3.40.50.10490 11 216 3.2E-94 T 14-10-2018 Theos_2225 8441c3ce67f8c8c55b9f496189e0ad40 255 Gene3D G3DSA:3.40.50.720 4 162 3.5E-32 T 14-10-2018 Theos_2225 8441c3ce67f8c8c55b9f496189e0ad40 255 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 112 5.6E-8 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 Theos_2225 8441c3ce67f8c8c55b9f496189e0ad40 255 SUPERFAMILY SSF51735 4 154 5.52E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2225 8441c3ce67f8c8c55b9f496189e0ad40 255 SUPERFAMILY SSF48179 156 253 3.32E-20 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Theos_2225 8441c3ce67f8c8c55b9f496189e0ad40 255 Pfam PF09130 Domain of unknown function (DUF1932) 183 251 2.7E-13 T 14-10-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal Theos_2225 8441c3ce67f8c8c55b9f496189e0ad40 255 Gene3D G3DSA:1.10.1040.10 164 255 3.2E-19 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Theos_2225 8441c3ce67f8c8c55b9f496189e0ad40 255 PIRSF PIRSF000103 1 196 4.4E-26 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Theos_2225 8441c3ce67f8c8c55b9f496189e0ad40 255 PIRSF PIRSF000103 191 250 1.6 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Theos_2366 637274a55d187f9ca9f56728e4c3497a 218 Gene3D G3DSA:1.10.10.10 119 217 1.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2366 637274a55d187f9ca9f56728e4c3497a 218 SMART SM00448 1 112 3.2E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_2366 637274a55d187f9ca9f56728e4c3497a 218 Pfam PF00072 Response regulator receiver domain 4 113 2.8E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_2366 637274a55d187f9ca9f56728e4c3497a 218 SMART SM00862 145 216 2.1E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_2366 637274a55d187f9ca9f56728e4c3497a 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.0E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_2366 637274a55d187f9ca9f56728e4c3497a 218 SUPERFAMILY SSF52172 2 176 2.87E-41 T 14-10-2018 IPR011006 CheY-like superfamily Theos_2366 637274a55d187f9ca9f56728e4c3497a 218 Gene3D G3DSA:3.40.50.2300 1 118 8.2E-34 T 14-10-2018 Theos_2364 a8038774cf5b06e0e182a33b6602bc41 119 Gene3D G3DSA:3.30.70.100 15 118 4.5E-36 T 14-10-2018 Theos_2364 a8038774cf5b06e0e182a33b6602bc41 119 SUPERFAMILY SSF54909 16 115 2.98E-29 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Theos_2364 a8038774cf5b06e0e182a33b6602bc41 119 Pfam PF03992 Antibiotic biosynthesis monooxygenase 17 91 3.7E-20 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain Theos_0915 c1c891e0131a1bef01dfd40e7f19471c 144 TIGRFAM TIGR00086 smpB: SsrA-binding protein 5 141 3.6E-53 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 Theos_0915 c1c891e0131a1bef01dfd40e7f19471c 144 SUPERFAMILY SSF74982 4 128 1.96E-49 T 14-10-2018 IPR023620 Small protein B Theos_0915 c1c891e0131a1bef01dfd40e7f19471c 144 Pfam PF01668 SmpB protein 5 142 1.5E-56 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 Theos_0915 c1c891e0131a1bef01dfd40e7f19471c 144 Gene3D G3DSA:2.40.280.10 1 125 1.7E-51 T 14-10-2018 IPR023620 Small protein B Theos_0915 c1c891e0131a1bef01dfd40e7f19471c 144 ProSitePatterns PS01317 SsrA-binding protein. 22 34 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site Theos_0915 c1c891e0131a1bef01dfd40e7f19471c 144 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 4 122 3.0E-48 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 Theos_0915 c1c891e0131a1bef01dfd40e7f19471c 144 Hamap MF_00023 SsrA-binding protein [smpB]. 1 144 64.395 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 Theos_0902 65abd0a40f38a3a9759ac0bdaf0d58f3 162 Pfam PF01782 RimM N-terminal domain 5 79 1.3E-5 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 Theos_0902 65abd0a40f38a3a9759ac0bdaf0d58f3 162 Gene3D G3DSA:2.40.30.60 1 84 3.1E-36 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 Theos_0902 65abd0a40f38a3a9759ac0bdaf0d58f3 162 Pfam PF05239 PRC-barrel domain 87 159 1.4E-8 T 14-10-2018 IPR027275 PRC-barrel domain Theos_0902 65abd0a40f38a3a9759ac0bdaf0d58f3 162 Gene3D G3DSA:2.30.30.240 85 155 2.9E-27 T 14-10-2018 Theos_0902 65abd0a40f38a3a9759ac0bdaf0d58f3 162 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 159 9.6E-27 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Theos_0902 65abd0a40f38a3a9759ac0bdaf0d58f3 162 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 3 160 18.309 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Theos_0902 65abd0a40f38a3a9759ac0bdaf0d58f3 162 SUPERFAMILY SSF50346 89 160 6.28E-11 T 14-10-2018 IPR011033 PRC-barrel-like superfamily Theos_0902 65abd0a40f38a3a9759ac0bdaf0d58f3 162 SUPERFAMILY SSF50447 3 83 2.47E-7 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_2017 4830f72ca04a469eeba65ba210f9b046 223 SUPERFAMILY SSF54690 83 215 7.32E-47 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Theos_2017 4830f72ca04a469eeba65ba210f9b046 223 Gene3D G3DSA:3.10.20.30 3 77 4.1E-20 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Theos_2017 4830f72ca04a469eeba65ba210f9b046 223 SUPERFAMILY SSF54285 1 77 9.32E-18 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Theos_2017 4830f72ca04a469eeba65ba210f9b046 223 Gene3D G3DSA:3.90.1170.40 78 215 1.4E-51 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Theos_2017 4830f72ca04a469eeba65ba210f9b046 223 Pfam PF02597 ThiS family 5 79 1.3E-15 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Theos_2017 4830f72ca04a469eeba65ba210f9b046 223 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 79 8.4E-19 T 14-10-2018 Theos_2017 4830f72ca04a469eeba65ba210f9b046 223 Pfam PF02391 MoaE protein 85 196 4.0E-40 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Theos_0120 a1d0dcbc16c1ed85081e2af124d3abab 135 Pfam PF03652 Holliday junction resolvase 1 132 2.3E-31 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Theos_0120 a1d0dcbc16c1ed85081e2af124d3abab 135 SUPERFAMILY SSF53098 2 132 2.47E-29 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_0120 a1d0dcbc16c1ed85081e2af124d3abab 135 SMART SM00732 1 100 6.4E-17 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 Theos_0120 a1d0dcbc16c1ed85081e2af124d3abab 135 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 5 131 3.5E-20 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Theos_0120 a1d0dcbc16c1ed85081e2af124d3abab 135 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 135 18.733 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Theos_0120 a1d0dcbc16c1ed85081e2af124d3abab 135 Gene3D G3DSA:3.30.420.140 1 133 1.1E-31 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 Theos_0664 498a8ff5c1d30519cd8cef1a17e60738 304 SUPERFAMILY SSF55120 66 292 2.26E-69 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0664 498a8ff5c1d30519cd8cef1a17e60738 304 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 128 142 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0664 498a8ff5c1d30519cd8cef1a17e60738 304 SMART SM00363 9 71 9.3E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0664 498a8ff5c1d30519cd8cef1a17e60738 304 Pfam PF01479 S4 domain 9 54 4.5E-11 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0664 498a8ff5c1d30519cd8cef1a17e60738 304 Gene3D G3DSA:3.10.290.10 1 62 4.1E-14 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Theos_0664 498a8ff5c1d30519cd8cef1a17e60738 304 SUPERFAMILY SSF55174 8 56 5.38E-10 T 14-10-2018 Theos_0664 498a8ff5c1d30519cd8cef1a17e60738 304 Pfam PF00849 RNA pseudouridylate synthase 81 235 4.9E-30 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0664 498a8ff5c1d30519cd8cef1a17e60738 304 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 6 291 9.8E-78 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0664 498a8ff5c1d30519cd8cef1a17e60738 304 Gene3D G3DSA:3.30.2350.10 63 281 5.1E-70 T 14-10-2018 Theos_1798 77dd69e89da217b4f6228e454dc8f9ce 437 Pfam PF07687 Peptidase dimerisation domain 175 334 1.9E-22 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain Theos_1798 77dd69e89da217b4f6228e454dc8f9ce 437 Gene3D G3DSA:3.30.70.360 178 347 1.4E-168 T 14-10-2018 Theos_1798 77dd69e89da217b4f6228e454dc8f9ce 437 Pfam PF01546 Peptidase family M20/M25/M40 69 429 1.7E-35 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 Theos_1798 77dd69e89da217b4f6228e454dc8f9ce 437 SUPERFAMILY SSF53187 3 433 1.37E-61 T 14-10-2018 Theos_1798 77dd69e89da217b4f6228e454dc8f9ce 437 Gene3D G3DSA:3.40.630.10 4 423 1.4E-168 T 14-10-2018 Theos_1798 77dd69e89da217b4f6228e454dc8f9ce 437 SUPERFAMILY SSF55031 280 344 4.71E-5 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Theos_1928 ce7a91260ec8228dbd161c010c4ea272 281 TIGRFAM TIGR00552 nadE: NAD+ synthetase 24 260 7.4E-60 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 Theos_1928 ce7a91260ec8228dbd161c010c4ea272 281 SUPERFAMILY SSF52402 7 262 3.35E-68 T 14-10-2018 Theos_1928 ce7a91260ec8228dbd161c010c4ea272 281 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 16 262 42.389 T 14-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 Theos_1928 ce7a91260ec8228dbd161c010c4ea272 281 Pfam PF02540 NAD synthase 24 259 2.6E-64 T 14-10-2018 IPR022310 NAD/GMP synthase Theos_1928 ce7a91260ec8228dbd161c010c4ea272 281 Gene3D G3DSA:3.40.50.620 16 263 1.2E-72 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0440 42a22cd196b7c22257e09271fe061ca1 334 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 327 1.1E-99 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Theos_0440 42a22cd196b7c22257e09271fe061ca1 334 Gene3D G3DSA:3.40.718.10 2 333 3.7E-151 T 14-10-2018 Theos_0440 42a22cd196b7c22257e09271fe061ca1 334 SUPERFAMILY SSF53659 2 331 9.18E-116 T 14-10-2018 Theos_0440 42a22cd196b7c22257e09271fe061ca1 334 SMART SM01329 4 327 6.0E-169 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Theos_1450 a0820ac35ca7d450e4e80b1b1e8988b0 260 SMART SM01021 15 259 2.7E-48 T 14-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 Theos_1450 a0820ac35ca7d450e4e80b1b1e8988b0 260 Pfam PF01036 Bacteriorhodopsin-like protein 18 248 7.1E-22 T 14-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 Theos_1450 a0820ac35ca7d450e4e80b1b1e8988b0 260 Gene3D G3DSA:1.20.1070.10 1 252 2.1E-98 T 14-10-2018 Theos_1450 a0820ac35ca7d450e4e80b1b1e8988b0 260 SUPERFAMILY SSF81321 15 246 1.83E-47 T 14-10-2018 Theos_1450 a0820ac35ca7d450e4e80b1b1e8988b0 260 PRINTS PR00251 Bacterial opsin signature 34 54 4.4E-12 T 14-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 Theos_1450 a0820ac35ca7d450e4e80b1b1e8988b0 260 PRINTS PR00251 Bacterial opsin signature 190 208 4.4E-12 T 14-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 Theos_1450 a0820ac35ca7d450e4e80b1b1e8988b0 260 PRINTS PR00251 Bacterial opsin signature 90 111 4.4E-12 T 14-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 Theos_1450 a0820ac35ca7d450e4e80b1b1e8988b0 260 PRINTS PR00251 Bacterial opsin signature 223 241 4.4E-12 T 14-10-2018 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 Theos_1450 a0820ac35ca7d450e4e80b1b1e8988b0 260 ProSitePatterns PS00950 Bacterial rhodopsins signature 1. 92 104 - T 14-10-2018 IPR018229 Rhodopsin, retinal binding site GO:0005216|GO:0006811|GO:0016020 Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 SUPERFAMILY SSF52096 453 761 1.49E-37 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 Gene3D G3DSA:3.90.226.10 453 762 2.7E-30 T 14-10-2018 Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 SUPERFAMILY SSF48179 335 399 1.02E-8 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 SUPERFAMILY SSF51735 1 189 3.38E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 Gene3D G3DSA:1.10.1040.10 192 304 3.7E-20 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 Pfam PF00378 Enoyl-CoA hydratase/isomerase 459 594 1.5E-11 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 285 8.4E-16 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 SUPERFAMILY SSF48179 189 305 5.36E-25 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 187 8.1E-49 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Theos_1531 72802b895de0f363d0fc4fe9de1d8684 764 Gene3D G3DSA:3.40.50.720 1 191 5.0E-60 T 14-10-2018 Theos_1562 610acee4b9244ad9e1553c04889a14bd 516 Gene3D G3DSA:3.40.309.10 290 479 1.7E-185 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Theos_1562 610acee4b9244ad9e1553c04889a14bd 516 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 287 294 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Theos_1562 610acee4b9244ad9e1553c04889a14bd 516 Pfam PF00171 Aldehyde dehydrogenase family 46 512 1.7E-155 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Theos_1562 610acee4b9244ad9e1553c04889a14bd 516 Gene3D G3DSA:3.40.605.10 40 503 1.7E-185 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_1562 610acee4b9244ad9e1553c04889a14bd 516 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 6 516 6.2E-218 T 14-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 Theos_1562 610acee4b9244ad9e1553c04889a14bd 516 SUPERFAMILY SSF53720 4 515 1.44E-158 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_1562 610acee4b9244ad9e1553c04889a14bd 516 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 315 326 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Theos_1452 fa0f1e762d9640331d54ff506a95e248 255 Pfam PF15461 Beta-carotene 15,15'-dioxygenase 24 240 1.8E-19 T 14-10-2018 IPR022270 Beta-carotene 15,15'-monooxygenase, Brp/Blh family GO:0016702|GO:0055114 KEGG: 00830+1.13.11.63|MetaCyc: PWY-6857 Theos_1452 fa0f1e762d9640331d54ff506a95e248 255 TIGRFAM TIGR03753 blh_monoox: beta-carotene 15,15'-monooxygenase, Brp/Blh family 21 237 1.8E-31 T 14-10-2018 IPR022270 Beta-carotene 15,15'-monooxygenase, Brp/Blh family GO:0016702|GO:0055114 KEGG: 00830+1.13.11.63|MetaCyc: PWY-6857 Theos_0606 d49c0ffce2d69c108ea90301a27e749b 276 Gene3D G3DSA:3.30.70.260 186 273 7.3E-30 T 14-10-2018 Theos_0606 d49c0ffce2d69c108ea90301a27e749b 276 SUPERFAMILY SSF53850 4 184 3.12E-63 T 14-10-2018 Theos_0606 d49c0ffce2d69c108ea90301a27e749b 276 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 219 226 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Theos_0606 d49c0ffce2d69c108ea90301a27e749b 276 SUPERFAMILY SSF55021 175 271 6.34E-26 T 14-10-2018 Theos_0606 d49c0ffce2d69c108ea90301a27e749b 276 Gene3D G3DSA:3.40.190.10 88 168 2.2E-29 T 14-10-2018 Theos_0606 d49c0ffce2d69c108ea90301a27e749b 276 Gene3D G3DSA:3.40.190.10 1 87 7.3E-30 T 14-10-2018 Theos_0606 d49c0ffce2d69c108ea90301a27e749b 276 Pfam PF00800 Prephenate dehydratase 6 182 1.3E-62 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Theos_0606 d49c0ffce2d69c108ea90301a27e749b 276 Pfam PF01842 ACT domain 193 257 1.8E-8 T 14-10-2018 IPR002912 ACT domain Theos_0738 dbb2d9c21dcf9705d92a0e79514de4c4 174 Pfam PF09335 SNARE associated Golgi protein 25 145 5.0E-15 T 14-10-2018 IPR032816 SNARE associated Golgi protein Theos_1850 adae0f3d6edbcc1a20138f0e5d8d524c 170 Pfam PF09189 Domain of unknown function (DUF1952) 95 167 7.9E-32 T 14-10-2018 IPR015272 Molybdopterin cofactor biosynthesis MoaD-related, C-terminal Theos_1850 adae0f3d6edbcc1a20138f0e5d8d524c 170 SUPERFAMILY SSF54285 3 88 1.74E-20 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Theos_1850 adae0f3d6edbcc1a20138f0e5d8d524c 170 SUPERFAMILY SSF103239 91 167 3.79E-30 T 14-10-2018 IPR036473 Molybdopterin cofactor biosynthesis MoaD-related, C-terminal domain superfamily Theos_1850 adae0f3d6edbcc1a20138f0e5d8d524c 170 Pfam PF02597 ThiS family 4 88 3.5E-15 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Theos_1850 adae0f3d6edbcc1a20138f0e5d8d524c 170 Gene3D G3DSA:3.30.1370.80 88 170 3.4E-32 T 14-10-2018 IPR036473 Molybdopterin cofactor biosynthesis MoaD-related, C-terminal domain superfamily Theos_1850 adae0f3d6edbcc1a20138f0e5d8d524c 170 Gene3D G3DSA:3.10.20.30 2 86 2.4E-29 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Theos_1850 adae0f3d6edbcc1a20138f0e5d8d524c 170 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 1.8E-19 T 14-10-2018 IPR010038 MoaD, archaeal-type Theos_0414 0774ca9c2dc008a910c77d4aa3550b27 188 Pfam PF14332 Domain of unknown function (DUF4388) 5 108 7.8E-8 T 14-10-2018 IPR025497 Domain of unknown function DUF4388 Theos_0364 2bddfb49b93cee602f1c251e83244a10 434 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 143 163 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Theos_0364 2bddfb49b93cee602f1c251e83244a10 434 SUPERFAMILY SSF102114 117 356 1.44E-49 T 14-10-2018 Theos_0364 2bddfb49b93cee602f1c251e83244a10 434 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 418 3.3E-98 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Theos_0364 2bddfb49b93cee602f1c251e83244a10 434 SMART SM00729 139 356 5.3E-42 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_0364 2bddfb49b93cee602f1c251e83244a10 434 Pfam PF00919 Uncharacterized protein family UPF0004 2 91 1.9E-22 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Theos_0364 2bddfb49b93cee602f1c251e83244a10 434 Gene3D G3DSA:3.40.50.12160 1 121 1.4E-18 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Theos_0364 2bddfb49b93cee602f1c251e83244a10 434 Gene3D G3DSA:3.80.30.20 136 364 1.3E-68 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Theos_0364 2bddfb49b93cee602f1c251e83244a10 434 Pfam PF04055 Radical SAM superfamily 145 311 1.3E-22 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_0680 aa8bf73de409ce559aeb9900e35c3012 381 Gene3D G3DSA:3.30.750.80 69 170 3.0E-36 T 14-10-2018 Theos_0680 aa8bf73de409ce559aeb9900e35c3012 381 Pfam PF02475 Met-10+ like-protein 109 251 3.7E-7 T 14-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 Theos_0680 aa8bf73de409ce559aeb9900e35c3012 381 Gene3D G3DSA:3.40.50.150 171 380 1.6E-61 T 14-10-2018 Theos_0680 aa8bf73de409ce559aeb9900e35c3012 381 Gene3D G3DSA:2.30.130.10 1 68 9.9E-17 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 Theos_0680 aa8bf73de409ce559aeb9900e35c3012 381 SUPERFAMILY SSF88697 4 66 9.44E-5 T 14-10-2018 IPR015947 PUA-like superfamily Theos_0680 aa8bf73de409ce559aeb9900e35c3012 381 SUPERFAMILY SSF53335 90 376 1.45E-58 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0506 4efc97b36b155eb297bdda5dfec10c14 349 Pfam PF14343 PrcB C-terminal 274 329 5.0E-14 T 14-10-2018 IPR025748 PrcB C-terminal domain Theos_0726 2c92f645be4bd718a9483d852ebaaf3a 238 Pfam PF04029 2-phosphosulpholactate phosphatase 16 213 4.2E-22 T 14-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Theos_0726 2c92f645be4bd718a9483d852ebaaf3a 238 Gene3D G3DSA:3.90.1560.10 6 217 1.0E-21 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Theos_0726 2c92f645be4bd718a9483d852ebaaf3a 238 SUPERFAMILY SSF142823 12 214 4.71E-22 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 Pfam PF00106 short chain dehydrogenase 5 189 1.9E-53 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 231 2.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.2E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 2.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 SUPERFAMILY SSF51735 5 214 3.97E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1072 4eee5579e66dea1c5c9b9ea3c5440f8f 231 Gene3D G3DSA:3.40.50.720 3 230 1.6E-69 T 14-10-2018 Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 169 4.1E-39 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 Pfam PF03454 MoeA C-terminal region (domain IV) 331 400 1.6E-16 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 SUPERFAMILY SSF63882 5 178 5.1E-50 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 Gene3D G3DSA:3.40.980.10 177 316 8.3E-104 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 179 308 8.2E-27 T 14-10-2018 IPR001453 MoaB/Mog domain Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 Gene3D G3DSA:2.170.190.11 48 143 8.3E-104 T 14-10-2018 Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 Gene3D G3DSA:2.40.340.10 329 397 2.4E-14 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 Gene3D G3DSA:3.90.105.10 27 176 8.3E-104 T 14-10-2018 Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 SUPERFAMILY SSF53218 179 322 1.22E-39 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 SMART SM00852 182 318 4.0E-41 T 14-10-2018 IPR001453 MoaB/Mog domain Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 Pfam PF00994 Probable molybdopterin binding domain 182 316 2.3E-22 T 14-10-2018 IPR001453 MoaB/Mog domain Theos_1748 94e95d7008fb0dbc8551a033b3017be3 404 SUPERFAMILY SSF63867 329 400 8.11E-15 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_2131 15f6571ec5ba7ce88cb34861c4ecc1b7 377 SUPERFAMILY SSF103473 3 375 4.58E-54 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_2131 15f6571ec5ba7ce88cb34861c4ecc1b7 377 Gene3D G3DSA:1.20.1250.20 195 377 1.6E-16 T 14-10-2018 Theos_2131 15f6571ec5ba7ce88cb34861c4ecc1b7 377 Pfam PF07690 Major Facilitator Superfamily 10 222 1.1E-21 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_2131 15f6571ec5ba7ce88cb34861c4ecc1b7 377 Gene3D G3DSA:1.20.1250.20 1 189 7.0E-32 T 14-10-2018 Theos_1322 170b446c7aa0ae28051d5968b4bedade 233 Gene3D G3DSA:3.40.50.150 11 137 1.6E-8 T 14-10-2018 Theos_1322 170b446c7aa0ae28051d5968b4bedade 233 Gene3D G3DSA:3.40.50.150 138 229 3.8E-22 T 14-10-2018 Theos_1322 170b446c7aa0ae28051d5968b4bedade 233 SUPERFAMILY SSF53335 10 223 8.54E-35 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1322 170b446c7aa0ae28051d5968b4bedade 233 Pfam PF01555 DNA methylase 155 217 1.0E-14 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 Theos_1322 170b446c7aa0ae28051d5968b4bedade 233 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 160 177 5.4E-21 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Theos_1322 170b446c7aa0ae28051d5968b4bedade 233 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 29 43 5.4E-21 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Theos_1322 170b446c7aa0ae28051d5968b4bedade 233 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 179 197 5.4E-21 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Theos_1322 170b446c7aa0ae28051d5968b4bedade 233 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 202 222 5.4E-21 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Theos_0051 32881ff8a15633960579a63a0af9faf3 64 Gene3D G3DSA:3.30.920.30 5 61 8.2E-9 T 14-10-2018 IPR038570 HicA superfamily Theos_0051 32881ff8a15633960579a63a0af9faf3 64 SUPERFAMILY SSF54786 6 61 3.02E-11 T 14-10-2018 Theos_0051 32881ff8a15633960579a63a0af9faf3 64 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 7 60 3.2E-10 T 14-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 Gene3D G3DSA:3.30.2090.10 184 268 2.2E-11 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 Gene3D G3DSA:3.30.70.1430 43 144 5.6E-24 T 14-10-2018 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 Gene3D G3DSA:1.20.1640.10 291 494 1.3E-42 T 14-10-2018 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 Gene3D G3DSA:1.20.1640.10 926 1099 3.9E-55 T 14-10-2018 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 SUPERFAMILY SSF82714 785 867 4.05E-10 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 SUPERFAMILY SSF82714 186 264 6.41E-8 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 SUPERFAMILY SSF82693 139 322 1.74E-19 T 14-10-2018 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 SUPERFAMILY SSF82693 628 722 3.82E-8 T 14-10-2018 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 SUPERFAMILY SSF82693 43 137 1.74E-25 T 14-10-2018 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.6E-39 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 1.6E-39 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 1.6E-39 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.6E-39 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 1.6E-39 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.6E-39 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 1.6E-39 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 Pfam PF00873 AcrB/AcrD/AcrF family 7 479 1.2E-118 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 Pfam PF00873 AcrB/AcrD/AcrF family 580 1088 1.8E-87 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 SUPERFAMILY SSF82866 865 1094 4.84E-46 T 14-10-2018 Theos_1421 8556bb67a2ab1071437af476c0d76908 1100 SUPERFAMILY SSF82866 290 487 3.01E-40 T 14-10-2018 Theos_1437 52ab6da7ffd679e87b4f7d3b773c79ed 332 Pfam PF00005 ABC transporter 23 143 1.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1437 52ab6da7ffd679e87b4f7d3b773c79ed 332 SUPERFAMILY SSF50331 217 330 1.36E-11 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Theos_1437 52ab6da7ffd679e87b4f7d3b773c79ed 332 Gene3D G3DSA:3.40.50.300 14 223 2.5E-58 T 14-10-2018 Theos_1437 52ab6da7ffd679e87b4f7d3b773c79ed 332 ProSitePatterns PS00211 ABC transporters family signature. 115 129 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1437 52ab6da7ffd679e87b4f7d3b773c79ed 332 SUPERFAMILY SSF52540 17 223 4.76E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1437 52ab6da7ffd679e87b4f7d3b773c79ed 332 SMART SM00382 19 190 3.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 276 289 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 26 303 58.293 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 SMART SM00382 101 276 7.7E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 SMART SM00963 7 76 7.0E-10 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 Gene3D G3DSA:1.20.120.140 22 96 4.5E-38 T 14-10-2018 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 SUPERFAMILY SSF47364 22 78 1.7E-16 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 Pfam PF00448 SRP54-type protein, GTPase domain 103 302 1.4E-73 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 SMART SM00962 102 303 9.5E-111 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 Gene3D G3DSA:3.40.50.300 97 304 2.3E-76 T 14-10-2018 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 29 302 3.5E-97 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 Pfam PF02881 SRP54-type protein, helical bundle domain 29 70 3.0E-7 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Theos_1784 b438a5bc3948385a99717c5faabbc3f2 304 SUPERFAMILY SSF52540 100 303 6.54E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1356 9b087ee9cd7aee3e2f268d4f63aa4853 116 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 1 86 4.0E-40 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Theos_1356 9b087ee9cd7aee3e2f268d4f63aa4853 116 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 113 2.1E-47 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Theos_1356 9b087ee9cd7aee3e2f268d4f63aa4853 116 PIRSF PIRSF006246 1 116 1.3E-52 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Theos_1356 9b087ee9cd7aee3e2f268d4f63aa4853 116 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 116 69.36 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Theos_1356 9b087ee9cd7aee3e2f268d4f63aa4853 116 SUPERFAMILY SSF50692 1 113 2.32E-48 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Theos_1356 9b087ee9cd7aee3e2f268d4f63aa4853 116 Gene3D G3DSA:2.40.40.20 1 116 2.1E-51 T 14-10-2018 Theos_1356 9b087ee9cd7aee3e2f268d4f63aa4853 116 Pfam PF02261 Aspartate decarboxylase 1 110 3.6E-50 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 Gene3D G3DSA:3.40.449.10 24 212 5.5E-230 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 249 264 - T 14-10-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 3 528 1.0E-213 T 14-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 8 528 54.799 T 14-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 Pfam PF01293 Phosphoenolpyruvate carboxykinase 14 481 2.8E-215 T 14-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 SUPERFAMILY SSF68923 4 211 4.01E-82 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 Gene3D G3DSA:3.90.228.20 213 513 5.5E-230 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 Gene3D G3DSA:2.170.8.10 34 330 5.5E-230 T 14-10-2018 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 SUPERFAMILY SSF53795 212 527 3.4E-134 T 14-10-2018 Theos_0033 aedcb1ffa5d30d80653ee9d255d41b36 529 PIRSF PIRSF006294 1 528 3.6E-235 T 14-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 Theos_0566 7c08e858ca4ac91c0f3da3e8ce7beb48 356 Pfam PF02585 GlcNAc-PI de-N-acetylase 82 246 1.1E-27 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 Theos_0566 7c08e858ca4ac91c0f3da3e8ce7beb48 356 SUPERFAMILY SSF102588 79 332 2.35E-45 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_0566 7c08e858ca4ac91c0f3da3e8ce7beb48 356 Gene3D G3DSA:3.40.50.10320 74 331 4.3E-48 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_1475 5a709ec9e8ff4e67c0114bb04fbf1f8d 364 Gene3D G3DSA:3.40.50.2000 15 356 2.8E-82 T 14-10-2018 Theos_1475 5a709ec9e8ff4e67c0114bb04fbf1f8d 364 Gene3D G3DSA:3.40.50.2000 170 346 2.8E-82 T 14-10-2018 Theos_1475 5a709ec9e8ff4e67c0114bb04fbf1f8d 364 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 5 362 5.9E-103 T 14-10-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 Theos_1475 5a709ec9e8ff4e67c0114bb04fbf1f8d 364 Pfam PF13439 Glycosyltransferase Family 4 15 174 8.9E-29 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Theos_1475 5a709ec9e8ff4e67c0114bb04fbf1f8d 364 SUPERFAMILY SSF53756 10 362 3.45E-81 T 14-10-2018 Theos_1475 5a709ec9e8ff4e67c0114bb04fbf1f8d 364 Pfam PF00534 Glycosyl transferases group 1 181 342 9.3E-28 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Theos_0589 e801e8f600569d5aecb0aeb4f436f8e6 627 SUPERFAMILY SSF55785 129 176 5.93E-6 T 14-10-2018 IPR035965 PAS domain superfamily Theos_0589 e801e8f600569d5aecb0aeb4f436f8e6 627 Gene3D G3DSA:3.30.420.10 442 600 1.5E-48 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Theos_0589 e801e8f600569d5aecb0aeb4f436f8e6 627 Pfam PF00929 Exonuclease 445 595 7.7E-31 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Theos_0589 e801e8f600569d5aecb0aeb4f436f8e6 627 SMART SM00479 442 604 1.8E-45 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Theos_0589 e801e8f600569d5aecb0aeb4f436f8e6 627 SUPERFAMILY SSF53098 443 608 5.2E-51 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_0589 e801e8f600569d5aecb0aeb4f436f8e6 627 Pfam PF13188 PAS domain 140 176 1.5E-4 T 14-10-2018 IPR000014 PAS domain Theos_0589 e801e8f600569d5aecb0aeb4f436f8e6 627 Gene3D G3DSA:3.30.450.20 129 265 3.8E-5 T 14-10-2018 Theos_0589 e801e8f600569d5aecb0aeb4f436f8e6 627 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 443 599 2.1E-33 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Theos_0096 f2cafd5f2c9d50c686293aa1697aaede 71 Pfam PF09851 Short C-terminal domain 45 70 5.9E-9 T 14-10-2018 IPR018649 SHOCT domain Theos_0980 2ab5db0be13801fee65e24a58073d78a 444 Gene3D G3DSA:3.40.50.12780 1 325 4.9E-129 T 14-10-2018 Theos_0980 2ab5db0be13801fee65e24a58073d78a 444 PIRSF PIRSF006444 1 444 2.0E-188 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 Theos_0980 2ab5db0be13801fee65e24a58073d78a 444 Pfam PF00501 AMP-binding enzyme 77 285 1.8E-14 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_0980 2ab5db0be13801fee65e24a58073d78a 444 Gene3D G3DSA:3.30.300.30 326 444 2.7E-31 T 14-10-2018 Theos_0980 2ab5db0be13801fee65e24a58073d78a 444 SUPERFAMILY SSF56801 28 439 5.1E-61 T 14-10-2018 Theos_0980 2ab5db0be13801fee65e24a58073d78a 444 Pfam PF14535 AMP-binding enzyme C-terminal domain 334 443 2.6E-30 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal Theos_0245 264644545863044f98b94d1490cdd7b1 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 10 30 1.5E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0245 264644545863044f98b94d1490cdd7b1 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 77 95 1.5E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0245 264644545863044f98b94d1490cdd7b1 301 SUPERFAMILY SSF54814 185 297 1.23E-35 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Theos_0245 264644545863044f98b94d1490cdd7b1 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 8 279 7.9E-70 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0245 264644545863044f98b94d1490cdd7b1 301 SUPERFAMILY SSF52540 10 206 8.27E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0245 264644545863044f98b94d1490cdd7b1 301 Gene3D G3DSA:3.40.50.300 1 184 1.8E-52 T 14-10-2018 Theos_0245 264644545863044f98b94d1490cdd7b1 301 Gene3D G3DSA:3.30.300.20 185 301 4.1E-40 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_0245 264644545863044f98b94d1490cdd7b1 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 131 1.5E-22 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_0245 264644545863044f98b94d1490cdd7b1 301 Pfam PF01926 50S ribosome-binding GTPase 10 126 1.1E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0245 264644545863044f98b94d1490cdd7b1 301 Pfam PF07650 KH domain 208 285 5.6E-17 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0245 264644545863044f98b94d1490cdd7b1 301 Hamap MF_00367 GTPase Era [era]. 5 296 32.902 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2257 3cde5424587258207dc280522ce692cb 168 Pfam PF13358 DDE superfamily endonuclease 1 128 7.2E-19 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain Theos_2257 3cde5424587258207dc280522ce692cb 168 Gene3D G3DSA:3.30.420.470 58 160 7.7E-6 T 14-10-2018 Theos_2306 6567612f2ca53a9a1f9732cb28213064 441 SUPERFAMILY SSF52317 241 431 1.48E-27 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_2306 6567612f2ca53a9a1f9732cb28213064 441 SUPERFAMILY SSF52540 5 198 1.79E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2306 6567612f2ca53a9a1f9732cb28213064 441 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 3 424 39.971 T 14-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 Theos_2306 6567612f2ca53a9a1f9732cb28213064 441 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 191 3.5E-18 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Theos_2306 6567612f2ca53a9a1f9732cb28213064 441 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 433 2.4E-117 T 14-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 Theos_2306 6567612f2ca53a9a1f9732cb28213064 441 Gene3D G3DSA:3.40.50.300 5 188 7.0E-29 T 14-10-2018 Theos_2306 6567612f2ca53a9a1f9732cb28213064 441 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 243 421 5.7E-27 T 14-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 SUPERFAMILY SSF50621 240 389 2.51E-40 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 SUPERFAMILY SSF51419 24 262 2.78E-55 T 14-10-2018 IPR029066 PLP-binding barrel Theos_2432 850c91d4a6420d1d59eb447904af243e 390 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 212 227 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Theos_2432 850c91d4a6420d1d59eb447904af243e 390 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 34 260 3.3E-38 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 28 347 3.0E-19 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 15 389 2.4E-90 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 Gene3D G3DSA:2.40.37.10 25 360 1.3E-91 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 53 71 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Theos_2432 850c91d4a6420d1d59eb447904af243e 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 347 360 2.4E-12 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 250 269 2.4E-12 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 73 85 2.4E-12 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 53 71 2.4E-12 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 Gene3D G3DSA:3.20.20.10 32 255 1.3E-91 T 14-10-2018 IPR029066 PLP-binding barrel Theos_2432 850c91d4a6420d1d59eb447904af243e 390 PRINTS PR01181 Diaminopimelate decarboxylase signature 155 164 5.8E-14 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 PRINTS PR01181 Diaminopimelate decarboxylase signature 357 379 5.8E-14 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 PRINTS PR01181 Diaminopimelate decarboxylase signature 71 88 5.8E-14 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Theos_2432 850c91d4a6420d1d59eb447904af243e 390 PRINTS PR01181 Diaminopimelate decarboxylase signature 277 295 5.8E-14 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Theos_1032 2431e7c5ce16dd378f0b020237b4bff6 86 Pfam PF00037 4Fe-4S binding domain 34 56 3.9E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1032 2431e7c5ce16dd378f0b020237b4bff6 86 Gene3D G3DSA:3.30.70.20 2 85 3.5E-32 T 14-10-2018 Theos_1032 2431e7c5ce16dd378f0b020237b4bff6 86 PRINTS PR00354 7Fe ferredoxin signature 9 19 5.4E-15 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Theos_1032 2431e7c5ce16dd378f0b020237b4bff6 86 PRINTS PR00354 7Fe ferredoxin signature 35 52 5.4E-15 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Theos_1032 2431e7c5ce16dd378f0b020237b4bff6 86 PRINTS PR00354 7Fe ferredoxin signature 19 29 5.4E-15 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Theos_1032 2431e7c5ce16dd378f0b020237b4bff6 86 SUPERFAMILY SSF54862 1 81 3.96E-19 T 14-10-2018 Theos_1032 2431e7c5ce16dd378f0b020237b4bff6 86 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1763 5eec0216b0301f71e745a054403c1a50 429 PIRSF PIRSF000505 6 429 2.1E-113 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Theos_1763 5eec0216b0301f71e745a054403c1a50 429 Gene3D G3DSA:3.65.10.10 24 232 1.7E-140 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Theos_1763 5eec0216b0301f71e745a054403c1a50 429 SUPERFAMILY SSF55205 12 426 2.29E-118 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Theos_1763 5eec0216b0301f71e745a054403c1a50 429 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 12 428 33.085 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Theos_1763 5eec0216b0301f71e745a054403c1a50 429 Gene3D G3DSA:3.65.10.10 16 420 1.7E-140 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Theos_1763 5eec0216b0301f71e745a054403c1a50 429 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 16 427 5.0E-118 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Theos_1763 5eec0216b0301f71e745a054403c1a50 429 ProSitePatterns PS00885 EPSP synthase signature 2. 342 360 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Theos_1763 5eec0216b0301f71e745a054403c1a50 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 422 6.9E-110 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Theos_1550 7e1112f633061b9b5cb45298451d9773 388 Gene3D G3DSA:1.20.1250.20 14 201 1.6E-9 T 14-10-2018 Theos_1550 7e1112f633061b9b5cb45298451d9773 388 Gene3D G3DSA:1.20.1250.20 207 385 4.8E-17 T 14-10-2018 Theos_1550 7e1112f633061b9b5cb45298451d9773 388 Pfam PF07690 Major Facilitator Superfamily 216 384 1.5E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_1550 7e1112f633061b9b5cb45298451d9773 388 SUPERFAMILY SSF103473 16 384 1.83E-36 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_0335 aa27075ab16ea96d46890a7210506e3e 522 SMART SM00382 21 482 4.5E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0335 aa27075ab16ea96d46890a7210506e3e 522 PIRSF PIRSF003128 1 522 1.5E-127 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Theos_0335 aa27075ab16ea96d46890a7210506e3e 522 Gene3D G3DSA:3.40.50.300 244 521 1.2E-56 T 14-10-2018 Theos_0335 aa27075ab16ea96d46890a7210506e3e 522 Gene3D G3DSA:3.40.50.300 1 235 5.6E-28 T 14-10-2018 Theos_0335 aa27075ab16ea96d46890a7210506e3e 522 SUPERFAMILY SSF52540 1 487 3.34E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0335 aa27075ab16ea96d46890a7210506e3e 522 Pfam PF02463 RecF/RecN/SMC N terminal domain 85 484 3.8E-11 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Theos_1127 6925c8c9687a77cb99debebbe6efb225 341 Gene3D G3DSA:3.40.50.2000 1 171 4.5E-48 T 14-10-2018 Theos_1127 6925c8c9687a77cb99debebbe6efb225 341 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 341 25.691 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1127 6925c8c9687a77cb99debebbe6efb225 341 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 135 2.2E-30 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1127 6925c8c9687a77cb99debebbe6efb225 341 Gene3D G3DSA:3.40.50.2000 172 326 6.1E-32 T 14-10-2018 Theos_1127 6925c8c9687a77cb99debebbe6efb225 341 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 184 295 1.6E-21 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 Theos_1127 6925c8c9687a77cb99debebbe6efb225 341 SUPERFAMILY SSF53756 3 339 1.21E-73 T 14-10-2018 Theos_2419 7a0e2db96f4efe8660c5873610ffcbb7 694 Gene3D G3DSA:3.40.50.300 7 115 2.6E-7 T 14-10-2018 Theos_2419 7a0e2db96f4efe8660c5873610ffcbb7 694 Pfam PF13361 UvrD-like helicase C-terminal domain 377 491 8.4E-10 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Theos_2419 7a0e2db96f4efe8660c5873610ffcbb7 694 SUPERFAMILY SSF52540 12 494 3.29E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2419 7a0e2db96f4efe8660c5873610ffcbb7 694 Pfam PF13245 AAA domain 16 247 3.1E-11 T 14-10-2018 Theos_2419 7a0e2db96f4efe8660c5873610ffcbb7 694 Gene3D G3DSA:3.40.50.300 194 257 2.7E-10 T 14-10-2018 Theos_2419 7a0e2db96f4efe8660c5873610ffcbb7 694 Gene3D G3DSA:3.40.50.300 377 509 8.8E-13 T 14-10-2018 Theos_2547 59ca58cded422c1e5e6dac2696b2ff9c 323 Pfam PF13614 AAA domain 56 216 4.1E-29 T 14-10-2018 IPR025669 AAA domain Theos_2547 59ca58cded422c1e5e6dac2696b2ff9c 323 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 10 42 4.8E-8 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 Theos_2547 59ca58cded422c1e5e6dac2696b2ff9c 323 Pfam PF12728 Helix-turn-helix domain 9 46 2.3E-6 T 14-10-2018 Theos_2547 59ca58cded422c1e5e6dac2696b2ff9c 323 Gene3D G3DSA:1.10.1660.10 3 45 3.4E-7 T 14-10-2018 Theos_2547 59ca58cded422c1e5e6dac2696b2ff9c 323 SUPERFAMILY SSF52540 55 308 1.05E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2547 59ca58cded422c1e5e6dac2696b2ff9c 323 Gene3D G3DSA:3.40.50.300 50 313 6.7E-46 T 14-10-2018 Theos_0161 0c97d96bdb5022621a60cfa258352c03 432 PIRSF PIRSF000243 2 432 8.8E-153 T 14-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 Theos_0161 0c97d96bdb5022621a60cfa258352c03 432 SUPERFAMILY SSF48695 45 428 1.17E-146 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily Theos_0161 0c97d96bdb5022621a60cfa258352c03 432 Pfam PF02335 Cytochrome c552 52 431 1.1E-146 T 14-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 Theos_0161 0c97d96bdb5022621a60cfa258352c03 432 Gene3D G3DSA:1.10.1130.10 56 312 3.7E-133 T 14-10-2018 Theos_0161 0c97d96bdb5022621a60cfa258352c03 432 Gene3D G3DSA:1.20.140.10 313 431 3.7E-133 T 14-10-2018 Theos_2108 da6e545679d3f8ed2b4cbf7eda03a83f 408 Pfam PF00709 Adenylosuccinate synthetase 5 401 2.9E-152 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Theos_2108 da6e545679d3f8ed2b4cbf7eda03a83f 408 Gene3D G3DSA:3.40.440.10 5 244 2.9E-88 T 14-10-2018 Theos_2108 da6e545679d3f8ed2b4cbf7eda03a83f 408 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Theos_2108 da6e545679d3f8ed2b4cbf7eda03a83f 408 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 402 1.5E-136 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Theos_2108 da6e545679d3f8ed2b4cbf7eda03a83f 408 Gene3D G3DSA:3.90.170.10 255 405 2.6E-52 T 14-10-2018 Theos_2108 da6e545679d3f8ed2b4cbf7eda03a83f 408 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 408 154.199 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Theos_2108 da6e545679d3f8ed2b4cbf7eda03a83f 408 SMART SM00788 3 403 1.7E-202 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Theos_2108 da6e545679d3f8ed2b4cbf7eda03a83f 408 SUPERFAMILY SSF52540 2 402 1.04E-141 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2108 da6e545679d3f8ed2b4cbf7eda03a83f 408 Gene3D G3DSA:1.10.300.10 99 189 2.9E-88 T 14-10-2018 Theos_1775 25c39a74d7e148cbe8ba2bbd5f31334a 67 Pfam PF00825 Ribonuclease P 1 62 2.0E-17 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Theos_1775 25c39a74d7e148cbe8ba2bbd5f31334a 67 Gene3D G3DSA:3.30.230.10 1 67 2.4E-18 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_1775 25c39a74d7e148cbe8ba2bbd5f31334a 67 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 63 1.3E-11 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Theos_1775 25c39a74d7e148cbe8ba2bbd5f31334a 67 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 9 23 - T 14-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 Theos_1775 25c39a74d7e148cbe8ba2bbd5f31334a 67 SUPERFAMILY SSF54211 1 65 1.57E-17 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 Pfam PF03466 LysR substrate binding domain 89 291 1.5E-36 T 14-10-2018 IPR005119 LysR, substrate-binding Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 SUPERFAMILY SSF46785 1 84 1.11E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 Gene3D G3DSA:3.40.190.10 91 290 8.8E-60 T 14-10-2018 Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 Gene3D G3DSA:3.40.190.10 161 261 8.8E-60 T 14-10-2018 Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 SUPERFAMILY SSF53850 90 296 3.98E-33 T 14-10-2018 Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 Gene3D G3DSA:1.10.10.10 1 84 1.2E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0242 65fdc5217049054d7c0cce552269b8c9 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.5E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_0302 3bd64c1bb2b9299d09500f310ac79f35 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 14-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0302 3bd64c1bb2b9299d09500f310ac79f35 126 Gene3D G3DSA:4.10.910.10 73 126 6.4E-30 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0302 3bd64c1bb2b9299d09500f310ac79f35 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.2E-32 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0302 3bd64c1bb2b9299d09500f310ac79f35 126 SUPERFAMILY SSF46946 2 123 3.66E-49 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Theos_0302 3bd64c1bb2b9299d09500f310ac79f35 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 7.3E-54 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0302 3bd64c1bb2b9299d09500f310ac79f35 126 Gene3D G3DSA:1.10.8.50 1 72 1.8E-30 T 14-10-2018 Theos_0302 3bd64c1bb2b9299d09500f310ac79f35 126 PIRSF PIRSF002134 1 125 5.4E-47 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0302 3bd64c1bb2b9299d09500f310ac79f35 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.234 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_1508 1733ade32929d99883172ded58637759 970 SUPERFAMILY SSF55781 213 356 5.02E-16 T 14-10-2018 Theos_1508 1733ade32929d99883172ded58637759 970 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 854 963 2.3E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1508 1733ade32929d99883172ded58637759 970 Gene3D G3DSA:3.30.450.40 184 360 1.7E-22 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1508 1733ade32929d99883172ded58637759 970 SMART SM00091 621 689 1.4E-6 T 14-10-2018 IPR000014 PAS domain Theos_1508 1733ade32929d99883172ded58637759 970 SUPERFAMILY SSF55785 608 733 1.42E-20 T 14-10-2018 IPR035965 PAS domain superfamily Theos_1508 1733ade32929d99883172ded58637759 970 SUPERFAMILY SSF55874 797 967 5.11E-51 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1508 1733ade32929d99883172ded58637759 970 SMART SM00387 853 965 7.1E-43 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1508 1733ade32929d99883172ded58637759 970 Gene3D G3DSA:1.10.287.130 735 808 9.9E-22 T 14-10-2018 Theos_1508 1733ade32929d99883172ded58637759 970 PRINTS PR00344 Bacterial sensor protein C-terminal signature 890 904 1.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1508 1733ade32929d99883172ded58637759 970 PRINTS PR00344 Bacterial sensor protein C-terminal signature 925 943 1.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1508 1733ade32929d99883172ded58637759 970 PRINTS PR00344 Bacterial sensor protein C-terminal signature 908 918 1.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1508 1733ade32929d99883172ded58637759 970 PRINTS PR00344 Bacterial sensor protein C-terminal signature 949 962 1.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_1508 1733ade32929d99883172ded58637759 970 SUPERFAMILY SSF55781 463 615 1.49E-8 T 14-10-2018 Theos_1508 1733ade32929d99883172ded58637759 970 Pfam PF13185 GAF domain 211 348 1.0E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1508 1733ade32929d99883172ded58637759 970 Gene3D G3DSA:3.30.450.20 613 734 9.1E-19 T 14-10-2018 Theos_1508 1733ade32929d99883172ded58637759 970 SUPERFAMILY SSF47384 731 809 1.96E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_1508 1733ade32929d99883172ded58637759 970 SMART SM00388 743 808 2.3E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_1508 1733ade32929d99883172ded58637759 970 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 618 742 1.1E-14 T 14-10-2018 IPR000014 PAS domain Theos_1508 1733ade32929d99883172ded58637759 970 Pfam PF08447 PAS fold 645 720 5.4E-11 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Theos_1508 1733ade32929d99883172ded58637759 970 SMART SM00065 483 617 0.021 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1508 1733ade32929d99883172ded58637759 970 SMART SM00065 212 358 4.2E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1508 1733ade32929d99883172ded58637759 970 Gene3D G3DSA:3.30.565.10 809 964 4.4E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1508 1733ade32929d99883172ded58637759 970 Pfam PF00512 His Kinase A (phospho-acceptor) domain 744 808 8.9E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_1508 1733ade32929d99883172ded58637759 970 Gene3D G3DSA:3.30.450.40 452 612 1.5E-12 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1508 1733ade32929d99883172ded58637759 970 Gene3D G3DSA:3.30.450.40 11 183 4.6E-5 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 19 519 4.0E-208 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 246 300 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 193 212 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 17 42 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 92 116 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 427 448 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 135 147 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 314 335 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 377 396 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 244 265 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 64 87 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 164 182 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 290 305 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 349 367 2.4E-86 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 Gene3D G3DSA:1.20.210.10 1 533 1.9E-211 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 SUPERFAMILY SSF81452 546 791 8.27E-59 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 Pfam PF00510 Cytochrome c oxidase subunit III 550 791 8.6E-26 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 Gene3D G3DSA:1.10.287.70 534 607 2.3E-41 T 14-10-2018 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 Gene3D G3DSA:1.20.120.80 608 791 2.1E-62 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 472 2.8E-140 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0036 2cd6ad1e83d4c5258df3c0525f43d0f0 791 SUPERFAMILY SSF81442 15 518 1.7E-168 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0329 6809387fcd634667801eb493b66aaf17 725 Gene3D G3DSA:3.90.650.10 14 362 6.2E-145 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Theos_0329 6809387fcd634667801eb493b66aaf17 725 Pfam PF02769 AIR synthase related protein, C-terminal domain 559 693 3.3E-16 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Theos_0329 6809387fcd634667801eb493b66aaf17 725 Pfam PF02769 AIR synthase related protein, C-terminal domain 204 342 1.0E-27 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Theos_0329 6809387fcd634667801eb493b66aaf17 725 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 725 277.304 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0329 6809387fcd634667801eb493b66aaf17 725 Gene3D G3DSA:3.30.1330.10 36 185 6.2E-145 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Theos_0329 6809387fcd634667801eb493b66aaf17 725 PIRSF PIRSF001587 1 725 3.5E-292 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0329 6809387fcd634667801eb493b66aaf17 725 Pfam PF00586 AIR synthase related protein, N-terminal domain 430 546 1.5E-19 T 14-10-2018 IPR016188 PurM-like, N-terminal domain Theos_0329 6809387fcd634667801eb493b66aaf17 725 Pfam PF00586 AIR synthase related protein, N-terminal domain 79 180 4.8E-24 T 14-10-2018 IPR016188 PurM-like, N-terminal domain Theos_0329 6809387fcd634667801eb493b66aaf17 725 SUPERFAMILY SSF56042 191 414 1.64E-49 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Theos_0329 6809387fcd634667801eb493b66aaf17 725 Gene3D G3DSA:3.30.1330.10 370 551 6.7E-61 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Theos_0329 6809387fcd634667801eb493b66aaf17 725 SUPERFAMILY SSF56042 556 723 1.36E-36 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Theos_0329 6809387fcd634667801eb493b66aaf17 725 Gene3D G3DSA:3.90.650.10 553 725 1.3E-44 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Theos_0329 6809387fcd634667801eb493b66aaf17 725 SUPERFAMILY SSF55326 382 548 4.45E-45 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Theos_0329 6809387fcd634667801eb493b66aaf17 725 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 12 722 1.8E-265 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0329 6809387fcd634667801eb493b66aaf17 725 SUPERFAMILY SSF55326 7 185 4.19E-51 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Theos_0776 839cb44e6bb2b766ce6b0fb0a375d7fa 253 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Theos_0776 839cb44e6bb2b766ce6b0fb0a375d7fa 253 SUPERFAMILY SSF52096 6 253 8.97E-78 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_0776 839cb44e6bb2b766ce6b0fb0a375d7fa 253 Gene3D G3DSA:1.10.12.10 199 253 2.5E-26 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Theos_0776 839cb44e6bb2b766ce6b0fb0a375d7fa 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 253 6.0E-55 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Theos_0776 839cb44e6bb2b766ce6b0fb0a375d7fa 253 Gene3D G3DSA:3.90.226.10 1 198 4.6E-71 T 14-10-2018 Theos_1372 025074fbc15adf4b8f72b1ad8a5a3bfc 439 Pfam PF00202 Aminotransferase class-III 25 430 7.7E-97 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_1372 025074fbc15adf4b8f72b1ad8a5a3bfc 439 Gene3D G3DSA:3.90.1150.10 9 428 5.7E-144 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_1372 025074fbc15adf4b8f72b1ad8a5a3bfc 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_1372 025074fbc15adf4b8f72b1ad8a5a3bfc 439 Gene3D G3DSA:3.40.640.10 58 324 5.7E-144 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_1372 025074fbc15adf4b8f72b1ad8a5a3bfc 439 SUPERFAMILY SSF53383 9 432 5.5E-125 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0836 c749ffa34d1818003718da5986f1bf04 400 Pfam PF09670 CRISPR-associated protein (Cas_Cas02710) 13 390 2.4E-107 T 14-10-2018 Theos_0836 c749ffa34d1818003718da5986f1bf04 400 Gene3D G3DSA:1.25.40.10 152 309 3.8E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0836 c749ffa34d1818003718da5986f1bf04 400 TIGRFAM TIGR02710 TIGR02710: CRISPR-associated protein, TIGR02710 family 13 390 8.1E-126 T 14-10-2018 IPR014082 CRISPR-associated protein, Cas02710 Theos_0891 48b6ee030d0fdc3e4edf90f0beb19d22 171 Pfam PF00196 Bacterial regulatory proteins, luxR family 114 167 1.8E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0891 48b6ee030d0fdc3e4edf90f0beb19d22 171 SMART SM00421 112 169 1.2E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0891 48b6ee030d0fdc3e4edf90f0beb19d22 171 Gene3D G3DSA:1.10.10.10 73 171 6.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0891 48b6ee030d0fdc3e4edf90f0beb19d22 171 SUPERFAMILY SSF46894 97 169 2.14E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Theos_0891 48b6ee030d0fdc3e4edf90f0beb19d22 171 ProSitePatterns PS00622 LuxR-type HTH domain signature. 129 156 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0891 48b6ee030d0fdc3e4edf90f0beb19d22 171 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 115 129 9.1E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0891 48b6ee030d0fdc3e4edf90f0beb19d22 171 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 157 9.1E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0891 48b6ee030d0fdc3e4edf90f0beb19d22 171 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 129 145 9.1E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_2391 6655032ddae80ea45074a02561f8868f 298 SUPERFAMILY SSF161098 62 283 7.59E-42 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2391 6655032ddae80ea45074a02561f8868f 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 295 2.1E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2391 6655032ddae80ea45074a02561f8868f 298 Gene3D G3DSA:1.10.3720.10 58 296 4.5E-51 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0527 48ec83b881fa4b162a0671b1873c1c66 722 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 150 716 2.7E-112 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ Theos_0527 48ec83b881fa4b162a0671b1873c1c66 722 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 191 627 4.0E-52 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Theos_1725 3417df97b2e59e67023d877e8d2a53eb 120 Pfam PF00072 Response regulator receiver domain 4 113 2.2E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_1725 3417df97b2e59e67023d877e8d2a53eb 120 Gene3D G3DSA:3.40.50.12740 2 120 4.3E-31 T 14-10-2018 Theos_1725 3417df97b2e59e67023d877e8d2a53eb 120 SUPERFAMILY SSF52172 3 118 1.85E-34 T 14-10-2018 IPR011006 CheY-like superfamily Theos_1725 3417df97b2e59e67023d877e8d2a53eb 120 SMART SM00448 2 113 9.5E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0867 30c3c36dae8df3413357ad73441e8527 478 SMART SM00849 12 196 6.0E-31 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0867 30c3c36dae8df3413357ad73441e8527 478 ProSitePatterns PS00380 Rhodanese signature 1. 398 409 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 Theos_0867 30c3c36dae8df3413357ad73441e8527 478 SUPERFAMILY SSF52821 239 370 7.46E-17 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0867 30c3c36dae8df3413357ad73441e8527 478 SMART SM00450 373 468 2.0E-25 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0867 30c3c36dae8df3413357ad73441e8527 478 SMART SM00450 272 368 0.01 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0867 30c3c36dae8df3413357ad73441e8527 478 Pfam PF00581 Rhodanese-like domain 374 464 7.5E-15 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0867 30c3c36dae8df3413357ad73441e8527 478 Gene3D G3DSA:3.40.250.10 266 359 5.7E-21 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0867 30c3c36dae8df3413357ad73441e8527 478 SUPERFAMILY SSF52821 369 472 2.36E-33 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0867 30c3c36dae8df3413357ad73441e8527 478 Gene3D G3DSA:3.60.15.10 1 262 2.6E-87 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_0867 30c3c36dae8df3413357ad73441e8527 478 Pfam PF00753 Metallo-beta-lactamase superfamily 14 180 5.6E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0867 30c3c36dae8df3413357ad73441e8527 478 Gene3D G3DSA:3.40.250.10 370 476 9.2E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0867 30c3c36dae8df3413357ad73441e8527 478 SUPERFAMILY SSF56281 1 261 2.24E-53 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_2326 c6f22b1afe8af8971cc4efc79903b5b0 280 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 3 251 3.6E-56 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Theos_2326 c6f22b1afe8af8971cc4efc79903b5b0 280 Pfam PF03186 CobD/Cbib protein 3 259 1.8E-78 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Theos_2326 c6f22b1afe8af8971cc4efc79903b5b0 280 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 280 74.484 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 SUPERFAMILY SSF82829 206 310 7.85E-9 T 14-10-2018 Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 Gene3D G3DSA:3.40.140.10 371 518 2.7E-34 T 14-10-2018 Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 Pfam PF01171 PP-loop family 23 195 8.4E-44 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 379 468 4.9E-17 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 SUPERFAMILY SSF52402 11 227 1.19E-51 T 14-10-2018 Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 23 199 1.1E-46 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 10 291 22.779 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 SUPERFAMILY SSF53927 379 508 1.09E-30 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 427 459 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Theos_1684 5fa0d829c0981ef7c1140c9bd6b10692 521 Gene3D G3DSA:3.40.50.620 11 228 2.6E-59 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 Gene3D G3DSA:3.40.50.300 155 326 9.3E-55 T 14-10-2018 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 SUPERFAMILY SSF52540 148 327 6.13E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 Pfam PF09269 Domain of unknown function (DUF1967) 348 411 2.1E-19 T 14-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 322 3.2E-126 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 225 243 5.3E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 160 180 5.3E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 208 223 5.3E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 181 199 5.3E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 344 411 1.8E-20 T 14-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 PIRSF PIRSF002401 1 357 2.4E-127 T 14-10-2018 IPR035101 GTP-binding protein, Obg-type Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 Hamap MF_01454 GTPase Obg [obg]. 1 323 45.062 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 SUPERFAMILY SSF102741 342 413 5.36E-17 T 14-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 Gene3D G3DSA:2.40.240.60 341 414 2.3E-28 T 14-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 ProSitePatterns PS00905 GTP1/OBG family signature. 210 223 - T 14-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 Pfam PF01018 GTP1/OBG 4 154 2.4E-56 T 14-10-2018 IPR006169 GTP1/OBG domain Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 SUPERFAMILY SSF82051 1 155 1.7E-52 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 159 311 4.1E-13 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 Pfam PF01926 50S ribosome-binding GTPase 159 277 4.8E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0256 65b3f5f43c3aedabad72b30d7a87a094 416 Gene3D G3DSA:2.70.210.12 1 154 2.2E-61 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily Theos_2070 41a21b2feaf595717338f60a29c7771e 216 SUPERFAMILY SSF53448 6 210 1.65E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_2070 41a21b2feaf595717338f60a29c7771e 216 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 89 96 - T 14-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Theos_2070 41a21b2feaf595717338f60a29c7771e 216 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 210 6.6E-61 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Theos_2070 41a21b2feaf595717338f60a29c7771e 216 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 5 211 39.372 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Theos_2070 41a21b2feaf595717338f60a29c7771e 216 Gene3D G3DSA:3.90.550.10 4 216 3.3E-70 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_2070 41a21b2feaf595717338f60a29c7771e 216 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 210 1.7E-51 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Theos_0494 52becae6634940c6d563bbe0882abccb 327 Pfam PF07687 Peptidase dimerisation domain 135 229 2.0E-5 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain Theos_0494 52becae6634940c6d563bbe0882abccb 327 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 44 53 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Theos_0494 52becae6634940c6d563bbe0882abccb 327 SUPERFAMILY SSF55031 135 244 7.67E-12 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Theos_0494 52becae6634940c6d563bbe0882abccb 327 Pfam PF01546 Peptidase family M20/M25/M40 45 322 2.6E-12 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 Theos_0494 52becae6634940c6d563bbe0882abccb 327 SUPERFAMILY SSF53187 28 324 1.5E-28 T 14-10-2018 Theos_0494 52becae6634940c6d563bbe0882abccb 327 Gene3D G3DSA:3.30.70.360 135 243 4.7E-10 T 14-10-2018 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 Pfam PF07517 SecA DEAD-like domain 7 396 7.1E-121 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 468 2.9E-202 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 Gene3D G3DSA:3.90.1440.10 229 362 5.4E-175 T 14-10-2018 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 SMART SM00958 228 352 2.6E-71 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 939 19.799 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 SUPERFAMILY SSF81886 727 942 2.22E-70 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 ProSitePatterns PS01312 SecA family signature. 570 585 - T 14-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 SMART SM00957 5 396 8.7E-267 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 Pfam PF01043 SecA preprotein cross-linking domain 232 352 8.7E-39 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 PRINTS PR00906 SecA protein signature 60 84 6.0E-68 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 PRINTS PR00906 SecA protein signature 167 187 6.0E-68 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 PRINTS PR00906 SecA protein signature 407 420 6.0E-68 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 PRINTS PR00906 SecA protein signature 114 124 6.0E-68 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 PRINTS PR00906 SecA protein signature 98 112 6.0E-68 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 PRINTS PR00906 SecA protein signature 370 387 6.0E-68 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 PRINTS PR00906 SecA protein signature 333 355 6.0E-68 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 Gene3D G3DSA:3.40.50.300 22 409 5.4E-175 T 14-10-2018 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 Gene3D G3DSA:1.10.3060.10 728 940 6.2E-67 T 14-10-2018 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 SUPERFAMILY SSF52540 5 409 3.85E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 Pfam PF07516 SecA Wing and Scaffold domain 724 936 1.0E-65 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 SUPERFAMILY SSF81767 227 362 2.75E-43 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 Theos_1271 2bddd162160770c8fdafc00e056f0eb8 997 SUPERFAMILY SSF52540 410 725 2.28E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1709 07edcf5b202b3bab406a1283d0b46a08 210 Pfam PF12697 Alpha/beta hydrolase family 27 191 4.1E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Theos_1709 07edcf5b202b3bab406a1283d0b46a08 210 SUPERFAMILY SSF53474 25 196 2.86E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1709 07edcf5b202b3bab406a1283d0b46a08 210 Gene3D G3DSA:3.40.50.1820 16 196 3.1E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 Gene3D G3DSA:2.30.42.10 99 189 3.1E-89 T 14-10-2018 Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 48 367 5.8E-85 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 Pfam PF03572 Peptidase family S41 199 361 2.7E-51 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 SUPERFAMILY SSF52096 42 366 8.12E-65 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 SUPERFAMILY SSF50156 76 194 4.93E-23 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 SMART SM00245 175 362 2.2E-52 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 Gene3D G3DSA:3.90.226.10 190 359 3.1E-89 T 14-10-2018 Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 100 170 7.3E-15 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 SMART SM00228 99 173 5.4E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_0860 57f9830edbeade6f2338b1e83a830e83 440 Gene3D G3DSA:3.30.750.44 42 337 3.1E-89 T 14-10-2018 Theos_0062 b5dd7bc8c4da68374554e9124601880b 219 Gene3D G3DSA:1.10.10.10 122 217 3.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0062 b5dd7bc8c4da68374554e9124601880b 219 SMART SM00862 147 215 2.8E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0062 b5dd7bc8c4da68374554e9124601880b 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 215 2.0E-14 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0062 b5dd7bc8c4da68374554e9124601880b 219 SMART SM00448 1 114 1.6E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0062 b5dd7bc8c4da68374554e9124601880b 219 Pfam PF00072 Response regulator receiver domain 3 114 2.0E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0062 b5dd7bc8c4da68374554e9124601880b 219 SUPERFAMILY SSF52172 1 171 7.4E-32 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0062 b5dd7bc8c4da68374554e9124601880b 219 Gene3D G3DSA:3.40.50.2300 1 121 1.3E-32 T 14-10-2018 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 SUPERFAMILY SSF52374 2 341 6.66E-110 T 14-10-2018 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 499 45.622 T 14-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 Pfam PF01588 Putative tRNA binding domain 527 618 2.6E-31 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 Gene3D G3DSA:1.10.730.10 337 500 2.2E-41 T 14-10-2018 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 SUPERFAMILY SSF50249 520 618 2.45E-36 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 3 133 4.5E-10 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 Gene3D G3DSA:2.170.220.10 116 226 4.4E-148 T 14-10-2018 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 Gene3D G3DSA:2.40.50.140 516 621 1.1E-38 T 14-10-2018 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 Pfam PF09334 tRNA synthetases class I (M) 137 360 2.2E-52 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 500 620 1.9E-41 T 14-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 Gene3D G3DSA:3.40.50.620 5 330 4.4E-148 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 470 9.9E-130 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 4.3E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 4.3E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 4.3E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 4.3E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 PRINTS PR01041 Methionyl-tRNA synthetase signature 255 270 4.3E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 PRINTS PR01041 Methionyl-tRNA synthetase signature 348 359 4.3E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Theos_0858 1be9c9a53853fd295a9da645d21922a6 621 SUPERFAMILY SSF47323 349 499 2.43E-33 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1803 e58a1d450ef8e755460ecad38d9447c8 460 Gene3D G3DSA:3.30.70.2740 330 411 9.7E-9 T 14-10-2018 Theos_1803 e58a1d450ef8e755460ecad38d9447c8 460 Gene3D G3DSA:3.30.70.2190 212 324 1.8E-5 T 14-10-2018 Theos_1803 e58a1d450ef8e755460ecad38d9447c8 460 Gene3D G3DSA:1.10.45.10 412 452 3.4E-10 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Theos_1803 e58a1d450ef8e755460ecad38d9447c8 460 Gene3D G3DSA:3.30.43.10 1 89 3.0E-25 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Theos_1803 e58a1d450ef8e755460ecad38d9447c8 460 Pfam PF02913 FAD linked oxidases, C-terminal domain 212 451 8.4E-67 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Theos_1803 e58a1d450ef8e755460ecad38d9447c8 460 Pfam PF01565 FAD binding domain 37 176 3.1E-43 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Theos_1803 e58a1d450ef8e755460ecad38d9447c8 460 SUPERFAMILY SSF56176 2 212 3.92E-68 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Theos_1803 e58a1d450ef8e755460ecad38d9447c8 460 SUPERFAMILY SSF55103 215 454 6.54E-70 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Theos_1803 e58a1d450ef8e755460ecad38d9447c8 460 Gene3D G3DSA:3.30.465.10 91 211 3.7E-35 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 64 7.8E-17 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 1 19 1.0E-40 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.0E-40 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 1.0E-40 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 1.0E-40 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 158 6.2E-60 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 SUPERFAMILY SSF52374 2 157 4.83E-46 T 14-10-2018 Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 1 159 36.168 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 Gene3D G3DSA:3.40.50.620 1 160 4.5E-58 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0941 c9e8cd3b3cb745fad8cc9b3e6f154afb 160 Pfam PF01467 Cytidylyltransferase-like 4 134 1.2E-21 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Theos_0411 4ef15b5ba68b19652334cf9f9e121e72 154 Gene3D G3DSA:2.60.40.790 13 152 5.8E-33 T 14-10-2018 IPR008978 HSP20-like chaperone Theos_0411 4ef15b5ba68b19652334cf9f9e121e72 154 SUPERFAMILY SSF49764 35 152 3.4E-33 T 14-10-2018 IPR008978 HSP20-like chaperone Theos_0411 4ef15b5ba68b19652334cf9f9e121e72 154 Pfam PF00011 Hsp20/alpha crystallin family 53 150 2.2E-20 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Theos_1409 6d01e75a219b685442cd9e6113209156 605 Gene3D G3DSA:3.30.70.2570 485 559 3.6E-34 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily Theos_1409 6d01e75a219b685442cd9e6113209156 605 Hamap MF_00071 Elongation factor 4 [lepA]. 1 603 289.522 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 Gene3D G3DSA:3.30.70.870 289 370 1.4E-35 T 14-10-2018 Theos_1409 6d01e75a219b685442cd9e6113209156 605 Pfam PF00679 Elongation factor G C-terminus 401 490 1.0E-20 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Theos_1409 6d01e75a219b685442cd9e6113209156 605 SUPERFAMILY SSF52540 2 207 2.32E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1409 6d01e75a219b685442cd9e6113209156 605 SUPERFAMILY SSF54980 402 499 3.21E-23 T 14-10-2018 IPR035647 EF-G domain III/V-like Theos_1409 6d01e75a219b685442cd9e6113209156 605 Gene3D G3DSA:3.40.50.300 4 187 2.5E-78 T 14-10-2018 Theos_1409 6d01e75a219b685442cd9e6113209156 605 Gene3D G3DSA:3.30.70.3380 371 484 1.5E-43 T 14-10-2018 Theos_1409 6d01e75a219b685442cd9e6113209156 605 TIGRFAM TIGR01393 lepA: elongation factor 4 6 600 3.2E-294 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 Pfam PF00009 Elongation factor Tu GTP binding domain 5 183 2.5E-53 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 Pfam PF06421 GTP-binding protein LepA C-terminus 493 599 1.9E-49 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal Theos_1409 6d01e75a219b685442cd9e6113209156 605 PRINTS PR00315 GTP-binding elongation factor signature 76 86 2.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 PRINTS PR00315 GTP-binding elongation factor signature 92 103 2.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 PRINTS PR00315 GTP-binding elongation factor signature 8 21 2.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 PRINTS PR00315 GTP-binding elongation factor signature 51 59 2.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 PRINTS PR00315 GTP-binding elongation factor signature 128 137 2.7E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 SUPERFAMILY SSF50447 167 291 6.82E-33 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_1409 6d01e75a219b685442cd9e6113209156 605 SMART SM00838 401 490 0.0038 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Theos_1409 6d01e75a219b685442cd9e6113209156 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Theos_1409 6d01e75a219b685442cd9e6113209156 605 SUPERFAMILY SSF54980 294 373 5.76E-19 T 14-10-2018 IPR035647 EF-G domain III/V-like Theos_1409 6d01e75a219b685442cd9e6113209156 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 177 1.2E-20 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 Pfam PF03144 Elongation factor Tu domain 2 207 278 5.4E-10 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Theos_1409 6d01e75a219b685442cd9e6113209156 605 Gene3D G3DSA:2.40.30.10 188 288 7.9E-35 T 14-10-2018 Theos_1163 c335a35e8eb9fa51be81f73a9bb14c96 709 SMART SM00327 304 476 2.0E-25 T 14-10-2018 IPR002035 von Willebrand factor, type A Theos_1163 c335a35e8eb9fa51be81f73a9bb14c96 709 Gene3D G3DSA:3.40.50.410 304 472 1.6E-36 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_1163 c335a35e8eb9fa51be81f73a9bb14c96 709 SUPERFAMILY SSF53300 305 469 5.7E-30 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_1163 c335a35e8eb9fa51be81f73a9bb14c96 709 SUPERFAMILY SSF52317 216 567 7.32E-19 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1163 c335a35e8eb9fa51be81f73a9bb14c96 709 Pfam PF00092 von Willebrand factor type A domain 307 466 1.7E-16 T 14-10-2018 IPR002035 von Willebrand factor, type A Theos_0528 24f1be8d3ad12a8fbc03a0e85f5df5dd 329 Gene3D G3DSA:3.40.190.10 115 260 1.4E-83 T 14-10-2018 Theos_0528 24f1be8d3ad12a8fbc03a0e85f5df5dd 329 SUPERFAMILY SSF53850 22 328 6.18E-53 T 14-10-2018 Theos_0528 24f1be8d3ad12a8fbc03a0e85f5df5dd 329 Pfam PF16868 NMT1-like family 25 326 1.6E-59 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Theos_0528 24f1be8d3ad12a8fbc03a0e85f5df5dd 329 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 6 326 9.2E-71 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Theos_0528 24f1be8d3ad12a8fbc03a0e85f5df5dd 329 Gene3D G3DSA:3.40.190.10 25 326 1.4E-83 T 14-10-2018 Theos_0790 6251b7f849e045829e12ad21aee446f2 146 Pfam PF05103 DivIVA protein 3 133 1.3E-35 T 14-10-2018 IPR007793 DivIVA family Theos_0790 6251b7f849e045829e12ad21aee446f2 146 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 34 1.3E-12 T 14-10-2018 IPR019933 DivIVA domain Theos_1778 fddc3caf35583ba935b2c8e8042a5c12 195 SUPERFAMILY SSF82708 128 183 4.51E-9 T 14-10-2018 IPR036867 R3H domain superfamily GO:0003676 Theos_1778 fddc3caf35583ba935b2c8e8042a5c12 195 Pfam PF01424 R3H domain 124 183 3.3E-15 T 14-10-2018 IPR001374 R3H domain GO:0003676 Theos_1778 fddc3caf35583ba935b2c8e8042a5c12 195 SMART SM00393 105 184 8.0E-21 T 14-10-2018 IPR001374 R3H domain GO:0003676 Theos_1778 fddc3caf35583ba935b2c8e8042a5c12 195 Pfam PF13083 KH domain 41 111 5.7E-10 T 14-10-2018 Theos_1778 fddc3caf35583ba935b2c8e8042a5c12 195 Gene3D G3DSA:3.30.300.20 35 119 1.0E-17 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_1778 fddc3caf35583ba935b2c8e8042a5c12 195 Gene3D G3DSA:3.30.1370.50 120 194 4.8E-25 T 14-10-2018 IPR036867 R3H domain superfamily GO:0003676 Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 110 119 - T 14-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 11 759 3.3E-188 T 14-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 SMART SM00847 363 451 9.8E-13 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 SMART SM00487 1 175 2.1E-16 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 Gene3D G3DSA:1.20.120.1080 345 438 1.0E-8 T 14-10-2018 Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 Gene3D G3DSA:3.40.50.300 3 168 5.4E-47 T 14-10-2018 Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 SMART SM00490 211 308 3.3E-16 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 Pfam PF04408 Helicase associated domain (HA2) 366 429 9.2E-14 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 Pfam PF00271 Helicase conserved C-terminal domain 198 308 6.3E-11 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 Gene3D G3DSA:3.40.50.300 169 324 2.1E-42 T 14-10-2018 Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 Pfam PF08482 ATP-dependent helicase C-terminal 629 759 3.0E-43 T 14-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal Theos_1572 c7bac00c3f84fdf31590f1210ad9df7f 759 SUPERFAMILY SSF52540 11 319 2.24E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2328 03a206bff0185e1ad0a0c81453357dcb 119 SUPERFAMILY SSF81301 11 90 8.05E-15 T 14-10-2018 Theos_2328 03a206bff0185e1ad0a0c81453357dcb 119 Gene3D G3DSA:3.30.460.10 9 103 9.0E-12 T 14-10-2018 Theos_2328 03a206bff0185e1ad0a0c81453357dcb 119 Pfam PF01909 Nucleotidyltransferase domain 20 75 6.1E-9 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 Gene3D G3DSA:3.20.20.70 1 326 6.2E-136 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 Pfam PF00490 Delta-aminolevulinic acid dehydratase 2 322 2.9E-131 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 14-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 SUPERFAMILY SSF51569 3 325 4.83E-126 T 14-10-2018 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 117 131 3.7E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 3.7E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 3.7E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 3.7E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 3.7E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 3.7E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 PIRSF PIRSF001415 1 326 1.5E-135 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0346 7078a77174c030ef2ecd90bb51746f9d 326 SMART SM01004 1 323 1.2E-203 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Theos_0423 a7014378817c5817c964d6c610ecb910 443 Gene3D G3DSA:3.30.10.20 292 356 1.4E-10 T 14-10-2018 Theos_0423 a7014378817c5817c964d6c610ecb910 443 SMART SM00740 292 357 1.8E-5 T 14-10-2018 IPR005543 PASTA domain Theos_0423 a7014378817c5817c964d6c610ecb910 443 SMART SM00740 222 288 2.6E-5 T 14-10-2018 IPR005543 PASTA domain Theos_0423 a7014378817c5817c964d6c610ecb910 443 SMART SM00740 156 221 1.2E-11 T 14-10-2018 IPR005543 PASTA domain Theos_0423 a7014378817c5817c964d6c610ecb910 443 SUPERFAMILY SSF54184 159 221 3.01E-5 T 14-10-2018 Theos_0423 a7014378817c5817c964d6c610ecb910 443 Gene3D G3DSA:3.30.10.20 224 289 3.7E-13 T 14-10-2018 Theos_0423 a7014378817c5817c964d6c610ecb910 443 Pfam PF03793 PASTA domain 298 355 8.7E-10 T 14-10-2018 IPR005543 PASTA domain Theos_0423 a7014378817c5817c964d6c610ecb910 443 Pfam PF03793 PASTA domain 228 287 1.6E-9 T 14-10-2018 IPR005543 PASTA domain Theos_0423 a7014378817c5817c964d6c610ecb910 443 Pfam PF03793 PASTA domain 161 221 3.3E-11 T 14-10-2018 IPR005543 PASTA domain Theos_0423 a7014378817c5817c964d6c610ecb910 443 Gene3D G3DSA:3.30.10.20 161 221 1.0E-13 T 14-10-2018 Theos_0326 edcd58ae647c43b7750d7a75f4111504 82 SUPERFAMILY SSF82697 3 79 9.24E-21 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_0326 edcd58ae647c43b7750d7a75f4111504 82 Gene3D G3DSA:3.30.1280.10 1 82 7.7E-30 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Theos_0326 edcd58ae647c43b7750d7a75f4111504 82 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 3 77 7.7E-18 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0326 edcd58ae647c43b7750d7a75f4111504 82 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 82 6.0E-23 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0326 edcd58ae647c43b7750d7a75f4111504 82 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 78 18.311 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0326 edcd58ae647c43b7750d7a75f4111504 82 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 77 2.6E-23 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Theos_0480 fb21dd9e91b30f6a372bb73b7dbeb51c 397 Pfam PF02706 Chain length determinant protein 7 95 3.1E-12 T 14-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 Theos_0480 fb21dd9e91b30f6a372bb73b7dbeb51c 397 Pfam PF13807 G-rich domain on putative tyrosine kinase 319 386 1.1E-6 T 14-10-2018 IPR032807 Tyrosine kinase, G-rich domain Theos_2019 428b9f0ef85aa2bf0f14791744a009f2 106 Gene3D G3DSA:3.30.70.2290 1 106 1.8E-51 T 14-10-2018 Theos_2019 428b9f0ef85aa2bf0f14791744a009f2 106 Pfam PF11482 Protein of unknown function (DUF3208) 2 106 3.4E-45 T 14-10-2018 IPR021576 Protein of unknown function DUF3208 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 SUPERFAMILY SSF53732 1 414 1.96E-127 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 Pfam PF00330 Aconitase family (aconitate hydratase) 58 403 2.9E-81 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 411 46.832 T 14-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 ProSitePatterns PS01244 Aconitase family signature 2. 344 357 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 410 1.7E-184 T 14-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 Gene3D G3DSA:3.30.499.10 265 416 1.4E-59 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 409 1.9E-174 T 14-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 ProSitePatterns PS00450 Aconitase family signature 1. 284 300 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 Gene3D G3DSA:3.30.499.20 4 261 3.6E-74 T 14-10-2018 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 PRINTS PR00415 Aconitase family signature 344 357 5.5E-12 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 PRINTS PR00415 Aconitase family signature 124 139 5.5E-12 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 PRINTS PR00415 Aconitase family signature 288 299 5.5E-12 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_1937 131b169266dd3175c6bd43edb1ff15ee 416 PRINTS PR00415 Aconitase family signature 110 123 5.5E-12 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Theos_2290 c9e26ba9d43d9e54cce6ccf1159c35d0 258 Gene3D G3DSA:3.40.1190.20 1 258 2.6E-103 T 14-10-2018 IPR029056 Ribokinase-like Theos_2290 c9e26ba9d43d9e54cce6ccf1159c35d0 258 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 257 1.2E-98 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Theos_2290 c9e26ba9d43d9e54cce6ccf1159c35d0 258 Pfam PF08543 Phosphomethylpyrimidine kinase 11 255 1.1E-92 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 Theos_2290 c9e26ba9d43d9e54cce6ccf1159c35d0 258 SUPERFAMILY SSF53613 2 257 1.11E-83 T 14-10-2018 IPR029056 Ribokinase-like Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 SUPERFAMILY SSF47203 247 414 4.35E-50 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 370 389 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 147 159 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 407 2.3E-39 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 32 141 1.7E-26 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 SUPERFAMILY SSF56645 22 260 7.46E-72 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 Gene3D G3DSA:2.40.110.10 144 248 1.0E-137 T 14-10-2018 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 Gene3D G3DSA:1.10.540.10 32 143 1.0E-137 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 Gene3D G3DSA:1.20.140.10 249 407 1.0E-137 T 14-10-2018 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 237 1.8E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Theos_1529 f9ee753f253dc86aa99388feb911a59f 580 Gene3D G3DSA:1.20.140.10 415 573 7.8E-41 T 14-10-2018 Theos_1593 7032dcf7b3b6bc868d1c99e95abd998d 352 SMART SM01003 10 149 2.9E-48 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Theos_1593 7032dcf7b3b6bc868d1c99e95abd998d 352 SUPERFAMILY SSF51735 149 307 2.53E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1593 7032dcf7b3b6bc868d1c99e95abd998d 352 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 24 149 2.9E-38 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Theos_1593 7032dcf7b3b6bc868d1c99e95abd998d 352 SUPERFAMILY SSF52283 24 344 7.31E-43 T 14-10-2018 Theos_1593 7032dcf7b3b6bc868d1c99e95abd998d 352 Gene3D G3DSA:3.40.50.720 23 336 6.3E-105 T 14-10-2018 Theos_1593 7032dcf7b3b6bc868d1c99e95abd998d 352 SMART SM01002 160 302 2.4E-44 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Theos_1593 7032dcf7b3b6bc868d1c99e95abd998d 352 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 162 335 1.1E-44 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Theos_1593 7032dcf7b3b6bc868d1c99e95abd998d 352 Gene3D G3DSA:3.40.50.720 142 310 6.3E-105 T 14-10-2018 Theos_0177 a1942e30bed2aa884c6431073f20045b 256 Gene3D G3DSA:3.30.1360.120 108 246 3.0E-11 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Theos_0177 a1942e30bed2aa884c6431073f20045b 256 Gene3D G3DSA:3.30.70.1400 19 99 4.2E-14 T 14-10-2018 Theos_0177 a1942e30bed2aa884c6431073f20045b 256 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 144 185 8.5E-11 T 14-10-2018 IPR017703 YgfZ/GcvT conserved site Theos_0177 a1942e30bed2aa884c6431073f20045b 256 SUPERFAMILY SSF103025 19 173 1.11E-24 T 14-10-2018 Theos_1388 5edbbd7a41360636849604f3ef56958f 617 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 14-10-2018 IPR020845 AMP-binding, conserved site Theos_1388 5edbbd7a41360636849604f3ef56958f 617 Gene3D G3DSA:3.40.50.12780 313 454 3.5E-38 T 14-10-2018 Theos_1388 5edbbd7a41360636849604f3ef56958f 617 Pfam PF00501 AMP-binding enzyme 10 455 2.4E-80 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_1388 5edbbd7a41360636849604f3ef56958f 617 Gene3D G3DSA:3.40.50.12780 1 312 3.8E-46 T 14-10-2018 Theos_1388 5edbbd7a41360636849604f3ef56958f 617 SUPERFAMILY SSF56801 4 590 6.02E-107 T 14-10-2018 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 27 494 1.5E-129 T 14-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 Gene3D G3DSA:3.20.70.20 21 573 4.9E-164 T 14-10-2018 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 Pfam PF02867 Ribonucleotide reductase, barrel domain 97 562 3.3E-113 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 386 409 1.5E-33 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 358 380 1.5E-33 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 440 467 1.5E-33 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 172 191 1.5E-33 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 280 291 1.5E-33 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 318 341 1.5E-33 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_1645 c5c06acaf6d1822ba7fc22355794f0fc 586 SUPERFAMILY SSF51998 95 566 3.97E-121 T 14-10-2018 Theos_0884 44bf037e4e5a2e0002101295c019642c 267 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 122 171 2.2E-7 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Theos_0884 44bf037e4e5a2e0002101295c019642c 267 SUPERFAMILY SSF53223 4 102 6.91E-29 T 14-10-2018 Theos_0884 44bf037e4e5a2e0002101295c019642c 267 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 7 262 3.3E-64 T 14-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Theos_0884 44bf037e4e5a2e0002101295c019642c 267 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 4 263 31.365 T 14-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Theos_0884 44bf037e4e5a2e0002101295c019642c 267 SUPERFAMILY SSF51735 103 259 3.71E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0884 44bf037e4e5a2e0002101295c019642c 267 Gene3D G3DSA:3.40.50.10860 8 248 1.4E-93 T 14-10-2018 Theos_0884 44bf037e4e5a2e0002101295c019642c 267 Gene3D G3DSA:3.40.50.720 103 238 1.4E-93 T 14-10-2018 Theos_0884 44bf037e4e5a2e0002101295c019642c 267 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 9 90 1.8E-26 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Theos_0284 fae24f8bc1fe1c9f0a3f8c8def6f21c3 141 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.1E-60 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0284 fae24f8bc1fe1c9f0a3f8c8def6f21c3 141 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.067 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0284 fae24f8bc1fe1c9f0a3f8c8def6f21c3 141 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 8.2E-50 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 Theos_0284 fae24f8bc1fe1c9f0a3f8c8def6f21c3 141 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.1E-35 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0284 fae24f8bc1fe1c9f0a3f8c8def6f21c3 141 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.1E-35 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0284 fae24f8bc1fe1c9f0a3f8c8def6f21c3 141 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.1E-35 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0284 fae24f8bc1fe1c9f0a3f8c8def6f21c3 141 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.1E-35 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0284 fae24f8bc1fe1c9f0a3f8c8def6f21c3 141 Gene3D G3DSA:3.90.1170.10 1 141 4.1E-54 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Theos_0284 fae24f8bc1fe1c9f0a3f8c8def6f21c3 141 SUPERFAMILY SSF54686 1 138 2.09E-57 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Theos_1936 6bbbe865735042b6fa34218e9171bce3 163 SUPERFAMILY SSF52016 3 158 4.12E-41 T 14-10-2018 Theos_1936 6bbbe865735042b6fa34218e9171bce3 163 Gene3D G3DSA:3.20.19.10 2 160 6.6E-47 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Theos_1936 6bbbe865735042b6fa34218e9171bce3 163 Pfam PF00694 Aconitase C-terminal domain 49 103 6.7E-18 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Theos_1936 6bbbe865735042b6fa34218e9171bce3 163 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 1 159 31.976 T 14-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 Theos_1936 6bbbe865735042b6fa34218e9171bce3 163 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 3 156 1.3E-49 T 14-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 Theos_1795 d85e62cd8f3cc6020bbede8ec3111721 209 Pfam PF00005 ABC transporter 21 166 5.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1795 d85e62cd8f3cc6020bbede8ec3111721 209 SMART SM00382 29 208 4.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1795 d85e62cd8f3cc6020bbede8ec3111721 209 Gene3D G3DSA:3.40.50.300 3 205 9.1E-59 T 14-10-2018 Theos_1795 d85e62cd8f3cc6020bbede8ec3111721 209 SUPERFAMILY SSF52540 3 202 2.28E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1795 d85e62cd8f3cc6020bbede8ec3111721 209 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1502 37574d29e6c0b2f36f155c3cbf7a007f 89 Gene3D G3DSA:1.10.287.10 1 89 2.9E-38 T 14-10-2018 Theos_1502 37574d29e6c0b2f36f155c3cbf7a007f 89 Pfam PF00312 Ribosomal protein S15 8 88 8.5E-37 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1502 37574d29e6c0b2f36f155c3cbf7a007f 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.311 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1502 37574d29e6c0b2f36f155c3cbf7a007f 89 SUPERFAMILY SSF47060 3 88 1.03E-34 T 14-10-2018 IPR009068 S15/NS1, RNA-binding Theos_1502 37574d29e6c0b2f36f155c3cbf7a007f 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 89 6.0E-28 T 14-10-2018 Theos_1502 37574d29e6c0b2f36f155c3cbf7a007f 89 SMART SM01387 8 88 1.6E-49 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1502 37574d29e6c0b2f36f155c3cbf7a007f 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 88 5.7E-36 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1502 37574d29e6c0b2f36f155c3cbf7a007f 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1931 230844b42823af1907fb0fe3d693c54d 271 TIGRFAM TIGR00761 argB: acetylglutamate kinase 3 249 6.1E-73 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1931 230844b42823af1907fb0fe3d693c54d 271 Pfam PF00696 Amino acid kinase family 3 250 2.6E-39 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Theos_1931 230844b42823af1907fb0fe3d693c54d 271 Gene3D G3DSA:3.40.1160.10 3 271 9.9E-76 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_1931 230844b42823af1907fb0fe3d693c54d 271 SUPERFAMILY SSF53633 3 270 3.01E-52 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_1931 230844b42823af1907fb0fe3d693c54d 271 PRINTS PR00474 Glutamate 5-kinase family signature 225 245 1.8E-12 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_1931 230844b42823af1907fb0fe3d693c54d 271 PRINTS PR00474 Glutamate 5-kinase family signature 30 44 1.8E-12 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_1931 230844b42823af1907fb0fe3d693c54d 271 PRINTS PR00474 Glutamate 5-kinase family signature 172 199 1.8E-12 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_1931 230844b42823af1907fb0fe3d693c54d 271 PIRSF PIRSF000728 1 271 1.2E-71 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_1931 230844b42823af1907fb0fe3d693c54d 271 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 3 271 48.291 T 14-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Gene3D G3DSA:3.90.740.10 225 414 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 873 23.009 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Gene3D G3DSA:1.10.730.10 652 810 1.9E-59 T 14-10-2018 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 124 141 5.6E-52 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 183 196 5.6E-52 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 150 166 5.6E-52 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 212 231 5.6E-52 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 529 551 5.6E-52 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 562 572 5.6E-52 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 490 508 5.6E-52 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Gene3D G3DSA:3.40.50.620 31 643 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 218 403 1.0E-69 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 50 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Gene3D G3DSA:2.30.210.10 577 633 0.0 T 14-10-2018 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 SUPERFAMILY SSF47323 678 873 8.04E-40 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Pfam PF08264 Anticodon-binding domain of tRNA 716 839 2.5E-24 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 SUPERFAMILY SSF52374 3 683 2.94E-152 T 14-10-2018 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Gene3D G3DSA:3.10.20.590 812 875 1.1E-24 T 14-10-2018 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 13 168 8.2E-26 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 416 576 7.2E-8 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 873 0.0 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 Pfam PF14795 Leucine-tRNA synthetase-specific domain 577 632 6.8E-25 T 14-10-2018 IPR023356 Leucyl-tRNA synthetase, domain 3 Theos_1861 a8beb1b15218bccabc6a4549f4fdedc1 875 SUPERFAMILY SSF50677 223 414 1.99E-57 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Theos_0758 f89527ba8f12ade9aa1d934f21b5706f 455 Gene3D G3DSA:2.30.40.10 32 438 1.1E-78 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Theos_0758 f89527ba8f12ade9aa1d934f21b5706f 455 Gene3D G3DSA:3.20.20.140 35 426 1.1E-78 T 14-10-2018 Theos_0758 f89527ba8f12ade9aa1d934f21b5706f 455 Pfam PF07969 Amidohydrolase family 32 439 1.0E-56 T 14-10-2018 IPR013108 Amidohydrolase 3 Theos_0758 f89527ba8f12ade9aa1d934f21b5706f 455 SUPERFAMILY SSF51556 34 425 2.19E-32 T 14-10-2018 IPR032466 Metal-dependent hydrolase Theos_0758 f89527ba8f12ade9aa1d934f21b5706f 455 Gene3D G3DSA:3.10.310.70 53 164 1.1E-78 T 14-10-2018 Theos_1789 ea2af7ed756e48c1d21eb4ada69984d7 548 Gene3D G3DSA:3.40.50.12780 10 444 1.4E-128 T 14-10-2018 Theos_1789 ea2af7ed756e48c1d21eb4ada69984d7 548 Pfam PF00501 AMP-binding enzyme 27 447 1.3E-115 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_1789 ea2af7ed756e48c1d21eb4ada69984d7 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 201 212 - T 14-10-2018 IPR020845 AMP-binding, conserved site Theos_1789 ea2af7ed756e48c1d21eb4ada69984d7 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 457 534 7.5E-23 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Theos_1789 ea2af7ed756e48c1d21eb4ada69984d7 548 SUPERFAMILY SSF56801 17 544 4.71E-164 T 14-10-2018 Theos_1789 ea2af7ed756e48c1d21eb4ada69984d7 548 Gene3D G3DSA:3.30.300.310 445 547 9.2E-35 T 14-10-2018 Theos_0797 d8de9797c6f7e37d76f71bb95ec8dd44 352 Gene3D G3DSA:2.120.10.30 22 352 1.7E-143 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Theos_0797 d8de9797c6f7e37d76f71bb95ec8dd44 352 SUPERFAMILY SSF50952 22 340 2.35E-42 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Theos_0797 d8de9797c6f7e37d76f71bb95ec8dd44 352 Pfam PF07995 Glucose / Sorbosone dehydrogenase 30 338 2.4E-92 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase Theos_0209 e5d2d12e051c0263144dffcc6be3f66f 323 SUPERFAMILY SSF52540 56 191 1.73E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0209 e5d2d12e051c0263144dffcc6be3f66f 323 Pfam PF03969 AFG1-like ATPase 23 206 3.7E-27 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 Theos_0209 e5d2d12e051c0263144dffcc6be3f66f 323 Pfam PF03969 AFG1-like ATPase 229 321 1.0E-10 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 Theos_0209 e5d2d12e051c0263144dffcc6be3f66f 323 Gene3D G3DSA:3.40.50.300 15 190 1.3E-12 T 14-10-2018 Theos_0854 f9bbffde1a9724c36de0477937ba58b0 379 Gene3D G3DSA:3.40.50.2300 124 365 2.6E-106 T 14-10-2018 Theos_0854 f9bbffde1a9724c36de0477937ba58b0 379 Gene3D G3DSA:3.40.50.2300 24 282 2.6E-106 T 14-10-2018 Theos_0854 f9bbffde1a9724c36de0477937ba58b0 379 SUPERFAMILY SSF53822 66 204 5.49E-5 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_0854 f9bbffde1a9724c36de0477937ba58b0 379 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 22 285 2.9E-43 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 Theos_0420 a4c906fdf45783fbdc07c86641e1e781 377 SMART SM00863 185 227 1.3E-10 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Theos_0420 a4c906fdf45783fbdc07c86641e1e781 377 SUPERFAMILY SSF50447 3 90 1.34E-12 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_0420 a4c906fdf45783fbdc07c86641e1e781 377 Pfam PF01411 tRNA synthetases class II (A) 17 94 2.1E-11 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 Theos_0420 a4c906fdf45783fbdc07c86641e1e781 377 SUPERFAMILY SSF55186 94 234 1.7E-30 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Theos_0420 a4c906fdf45783fbdc07c86641e1e781 377 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 185 225 1.1E-7 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Theos_0420 a4c906fdf45783fbdc07c86641e1e781 377 Gene3D G3DSA:3.30.980.10 91 244 1.2E-39 T 14-10-2018 Theos_0420 a4c906fdf45783fbdc07c86641e1e781 377 Gene3D G3DSA:2.40.30.130 1 90 1.2E-19 T 14-10-2018 Theos_0005 82545718b40fe8ac7edcf6db5b769543 396 SUPERFAMILY SSF52743 101 383 2.36E-77 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_0005 82545718b40fe8ac7edcf6db5b769543 396 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 165 175 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site Theos_0005 82545718b40fe8ac7edcf6db5b769543 396 PRINTS PR00723 Subtilisin serine protease family (S8) signature 120 139 1.1E-21 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_0005 82545718b40fe8ac7edcf6db5b769543 396 PRINTS PR00723 Subtilisin serine protease family (S8) signature 161 174 1.1E-21 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_0005 82545718b40fe8ac7edcf6db5b769543 396 PRINTS PR00723 Subtilisin serine protease family (S8) signature 336 352 1.1E-21 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_0005 82545718b40fe8ac7edcf6db5b769543 396 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 125 136 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site Theos_0005 82545718b40fe8ac7edcf6db5b769543 396 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 337 347 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site Theos_0005 82545718b40fe8ac7edcf6db5b769543 396 Pfam PF00082 Subtilase family 121 375 1.1E-52 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Theos_0005 82545718b40fe8ac7edcf6db5b769543 396 Gene3D G3DSA:3.40.50.200 89 386 1.1E-85 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_0777 c508c19290eb7f77ebf9d8940aa53a42 171 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 82 166 6.0E-36 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 Theos_0777 c508c19290eb7f77ebf9d8940aa53a42 171 SUPERFAMILY SSF55200 83 168 6.02E-31 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 Theos_0777 c508c19290eb7f77ebf9d8940aa53a42 171 Gene3D G3DSA:3.10.20.80 1 74 1.7E-32 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Theos_0777 c508c19290eb7f77ebf9d8940aa53a42 171 SUPERFAMILY SSF54364 4 77 8.76E-28 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Theos_0777 c508c19290eb7f77ebf9d8940aa53a42 171 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 168 7.5E-59 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Theos_0777 c508c19290eb7f77ebf9d8940aa53a42 171 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 169 28.27 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Theos_0777 c508c19290eb7f77ebf9d8940aa53a42 171 Gene3D G3DSA:3.30.110.10 75 169 1.3E-35 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 Theos_0777 c508c19290eb7f77ebf9d8940aa53a42 171 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 6 75 4.3E-31 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Theos_2227 cef4fb04465bf1367e936e2eacf50eb8 236 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 133 1.3E-20 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 Theos_2227 cef4fb04465bf1367e936e2eacf50eb8 236 Gene3D G3DSA:3.40.50.10320 1 236 7.2E-72 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_2227 cef4fb04465bf1367e936e2eacf50eb8 236 SUPERFAMILY SSF102588 1 236 1.57E-45 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_0672 414bf32a2087862e59f4c6907886b086 305 SUPERFAMILY SSF55048 125 190 7.46E-15 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding Theos_0672 414bf32a2087862e59f4c6907886b086 305 SUPERFAMILY SSF52151 1 302 4.19E-72 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Theos_0672 414bf32a2087862e59f4c6907886b086 305 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 295 2.5E-53 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain Theos_0672 414bf32a2087862e59f4c6907886b086 305 Gene3D G3DSA:3.40.366.10 5 278 3.5E-110 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 Theos_0672 414bf32a2087862e59f4c6907886b086 305 Pfam PF00698 Acyl transferase domain 5 286 1.4E-42 T 14-10-2018 IPR014043 Acyl transferase Theos_0672 414bf32a2087862e59f4c6907886b086 305 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 282 9.5E-92 T 14-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 Theos_0672 414bf32a2087862e59f4c6907886b086 305 Gene3D G3DSA:3.30.70.250 122 190 3.5E-110 T 14-10-2018 Theos_0672 414bf32a2087862e59f4c6907886b086 305 PIRSF PIRSF000446 1 303 6.5E-89 T 14-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 SUPERFAMILY SSF51735 8 257 1.63E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 Gene3D G3DSA:1.10.8.400 204 258 4.3E-21 T 14-10-2018 Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 253 8.3E-84 T 14-10-2018 Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 PIRSF PIRSF000094 3 259 1.4E-101 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 Gene3D G3DSA:3.40.50.720 9 201 2.2E-38 T 14-10-2018 Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0206 572264b2d11c49cdfd386ae4d5f9558a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0857 61e1f270957a1d2b2fb8196c2b9fe28c 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 9 222 3.6E-73 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Theos_0857 61e1f270957a1d2b2fb8196c2b9fe28c 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 5 225 30.703 T 14-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Theos_0857 61e1f270957a1d2b2fb8196c2b9fe28c 227 Gene3D G3DSA:3.40.50.1360 1 129 2.4E-51 T 14-10-2018 Theos_0857 61e1f270957a1d2b2fb8196c2b9fe28c 227 SUPERFAMILY SSF100950 6 179 2.93E-41 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Theos_0857 61e1f270957a1d2b2fb8196c2b9fe28c 227 SUPERFAMILY SSF75445 131 208 2.88E-22 T 14-10-2018 Theos_0857 61e1f270957a1d2b2fb8196c2b9fe28c 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 55 219 1.3E-57 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Theos_0857 61e1f270957a1d2b2fb8196c2b9fe28c 227 Gene3D G3DSA:3.30.70.260 130 196 1.9E-29 T 14-10-2018 Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 102 110 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 Pfam PF00483 Nucleotidyl transferase 8 280 1.4E-63 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 387 2.9E-147 T 14-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 SUPERFAMILY SSF53448 3 367 7.66E-77 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 414 50.132 T 14-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 SUPERFAMILY SSF51161 302 412 1.16E-18 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 Gene3D G3DSA:3.90.550.10 2 295 5.2E-89 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 200 210 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 Theos_1876 cabf0e0a62f74a9692c34a0b80e61661 414 Gene3D G3DSA:2.160.10.10 296 412 3.7E-33 T 14-10-2018 Theos_0454 ef47f0000373e7adffe07cf99e520781 466 Pfam PF02589 LUD domain 69 288 4.5E-44 T 14-10-2018 IPR003741 LUD domain Theos_0454 ef47f0000373e7adffe07cf99e520781 466 Pfam PF11870 Domain of unknown function (DUF3390) 390 455 1.1E-11 T 14-10-2018 IPR024569 4Fe-4S binding protein, C-terminal Theos_0454 ef47f0000373e7adffe07cf99e520781 466 Pfam PF13183 4Fe-4S dicluster domain 305 371 2.6E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_0454 ef47f0000373e7adffe07cf99e520781 466 SUPERFAMILY SSF100950 63 289 4.6E-36 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Theos_0454 ef47f0000373e7adffe07cf99e520781 466 Gene3D G3DSA:3.40.50.10420 148 291 7.7E-11 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Theos_0454 ef47f0000373e7adffe07cf99e520781 466 SUPERFAMILY SSF46548 274 386 8.37E-19 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Theos_0454 ef47f0000373e7adffe07cf99e520781 466 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 22 417 2.2E-134 T 14-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 SUPERFAMILY SSF53067 3 248 2.99E-76 T 14-10-2018 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 Gene3D G3DSA:3.30.420.40 1 246 4.1E-86 T 14-10-2018 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 TIGRFAM TIGR01312 XylB: xylulokinase 5 462 3.0E-139 T 14-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 Gene3D G3DSA:3.30.420.40 247 482 8.8E-62 T 14-10-2018 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 353 373 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 PIRSF PIRSF000538 1 488 4.9E-138 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 PRINTS PR00475 Hexokinase family signature 152 168 9.4E-5 T 14-10-2018 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 PRINTS PR00475 Hexokinase family signature 5 21 9.4E-5 T 14-10-2018 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 PRINTS PR00475 Hexokinase family signature 422 438 9.4E-5 T 14-10-2018 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 438 6.4E-25 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 245 4.9E-70 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Theos_1292 30d4983d285b393a40ae9fa709f871fe 489 SUPERFAMILY SSF53067 253 462 9.5E-50 T 14-10-2018 Theos_1781 efb7148c9b0702197c49995c917be231 242 Pfam PF00005 ABC transporter 21 165 3.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1781 efb7148c9b0702197c49995c917be231 242 SUPERFAMILY SSF52540 5 238 8.05E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1781 efb7148c9b0702197c49995c917be231 242 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1781 efb7148c9b0702197c49995c917be231 242 Gene3D G3DSA:3.40.50.300 3 242 3.2E-66 T 14-10-2018 Theos_1781 efb7148c9b0702197c49995c917be231 242 SMART SM00382 29 215 1.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1781 efb7148c9b0702197c49995c917be231 242 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 5 242 9.0E-97 T 14-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 Theos_2394 ddaeecad3a320c54610516a46276faff 314 Gene3D G3DSA:3.40.190.10 24 285 3.8E-57 T 14-10-2018 Theos_2394 ddaeecad3a320c54610516a46276faff 314 Gene3D G3DSA:3.40.190.10 124 233 3.8E-57 T 14-10-2018 Theos_2394 ddaeecad3a320c54610516a46276faff 314 Pfam PF13531 Bacterial extracellular solute-binding protein 26 273 5.0E-32 T 14-10-2018 Theos_2394 ddaeecad3a320c54610516a46276faff 314 SUPERFAMILY SSF53850 21 292 1.12E-55 T 14-10-2018 Theos_2394 ddaeecad3a320c54610516a46276faff 314 PIRSF PIRSF002825 15 304 1.1E-49 T 14-10-2018 IPR026045 Ferric binding protein Theos_2027 2a2af9cc0d27015307373c7c15e56b47 159 SUPERFAMILY SSF55083 2 154 3.4E-56 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Theos_2027 2a2af9cc0d27015307373c7c15e56b47 159 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 4 131 5.0E-37 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Theos_2027 2a2af9cc0d27015307373c7c15e56b47 159 Gene3D G3DSA:3.30.70.560 1 157 6.6E-58 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Theos_2027 2a2af9cc0d27015307373c7c15e56b47 159 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 3 131 2.3E-43 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Theos_0172 54daaf0cae950f715f2ec12af19fea12 223 SUPERFAMILY SSF52172 3 173 1.22E-33 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0172 54daaf0cae950f715f2ec12af19fea12 223 Gene3D G3DSA:3.40.50.2300 1 120 6.2E-30 T 14-10-2018 Theos_0172 54daaf0cae950f715f2ec12af19fea12 223 SMART SM00448 2 112 4.7E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0172 54daaf0cae950f715f2ec12af19fea12 223 SMART SM00862 143 219 7.2E-31 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0172 54daaf0cae950f715f2ec12af19fea12 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 219 2.3E-29 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0172 54daaf0cae950f715f2ec12af19fea12 223 Gene3D G3DSA:1.10.10.10 121 223 1.1E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0172 54daaf0cae950f715f2ec12af19fea12 223 Pfam PF00072 Response regulator receiver domain 4 112 1.5E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_1092 fd4dfd72962f7955e2a9df49a3cd78ce 82 SUPERFAMILY SSF46785 20 70 3.58E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1092 fd4dfd72962f7955e2a9df49a3cd78ce 82 Gene3D G3DSA:1.10.10.10 18 82 7.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1092 fd4dfd72962f7955e2a9df49a3cd78ce 82 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 1.9E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_1092 fd4dfd72962f7955e2a9df49a3cd78ce 82 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 25 40 1.9E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_1092 fd4dfd72962f7955e2a9df49a3cd78ce 82 Pfam PF01022 Bacterial regulatory protein, arsR family 20 43 1.7E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_1092 fd4dfd72962f7955e2a9df49a3cd78ce 82 SMART SM00418 6 68 1.3E-4 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_2457 54e4f68a9a498cb45219b380db8b8ee8 431 Pfam PF14535 AMP-binding enzyme C-terminal domain 338 426 1.9E-14 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal Theos_2457 54e4f68a9a498cb45219b380db8b8ee8 431 Gene3D G3DSA:3.40.50.12780 2 329 2.8E-106 T 14-10-2018 Theos_2457 54e4f68a9a498cb45219b380db8b8ee8 431 Pfam PF00501 AMP-binding enzyme 95 288 9.2E-13 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_2457 54e4f68a9a498cb45219b380db8b8ee8 431 Gene3D G3DSA:3.30.300.30 330 429 9.9E-22 T 14-10-2018 Theos_2457 54e4f68a9a498cb45219b380db8b8ee8 431 SUPERFAMILY SSF56801 42 398 2.62E-49 T 14-10-2018 Theos_1678 4df5699864fc4f47d325beb6c09b8a58 144 Gene3D G3DSA:2.60.120.1140 34 143 1.0E-9 T 14-10-2018 IPR038695 Saro_0823-like superfamily Theos_1678 4df5699864fc4f47d325beb6c09b8a58 144 Pfam PF02643 Uncharacterized ACR, COG1430 49 142 1.9E-9 T 14-10-2018 IPR003795 Protein of unknown function DUF192 Theos_0872 96bf5127f26fac3d2361a792ce28fa9f 353 Pfam PF04285 Protein of unknown function (DUF444) 158 345 2.0E-49 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 Theos_0872 96bf5127f26fac3d2361a792ce28fa9f 353 Pfam PF04285 Protein of unknown function (DUF444) 67 145 2.4E-10 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 Theos_0872 96bf5127f26fac3d2361a792ce28fa9f 353 SUPERFAMILY SSF53300 179 295 3.34E-8 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 257 4.0E-75 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 3.9E-12 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 Gene3D G3DSA:1.10.3730.10 158 259 3.1E-33 T 14-10-2018 Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 213 235 - T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 SUPERFAMILY SSF48179 154 259 5.1E-30 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 155 257 1.2E-34 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 SUPERFAMILY SSF51735 1 153 3.82E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 PIRSF PIRSF000193 1 260 3.5E-61 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 257 24.507 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Theos_1337 e4c435c58b56f4edee0c706113d73e2f 261 Gene3D G3DSA:3.40.50.720 1 157 2.1E-31 T 14-10-2018 Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 3.9E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 Gene3D G3DSA:3.40.190.10 114 276 4.8E-42 T 14-10-2018 Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 SUPERFAMILY SSF46785 1 83 3.02E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 Gene3D G3DSA:1.10.10.10 1 88 5.4E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.9E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.9E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.9E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 Pfam PF03466 LysR substrate binding domain 84 282 1.5E-29 T 14-10-2018 IPR005119 LysR, substrate-binding Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 SUPERFAMILY SSF53850 88 282 1.0E-25 T 14-10-2018 Theos_2158 0a8665ef547e81cee6e3c44396b2a78b 285 Gene3D G3DSA:3.40.190.10 156 259 4.8E-42 T 14-10-2018 Theos_0413 8051a73f3941a564bc273d5d4dca7181 310 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 18 156 1.7E-33 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 Theos_0413 8051a73f3941a564bc273d5d4dca7181 310 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 5 191 25.019 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 Theos_0413 8051a73f3941a564bc273d5d4dca7181 310 Gene3D G3DSA:3.40.50.150 6 197 9.3E-48 T 14-10-2018 Theos_0413 8051a73f3941a564bc273d5d4dca7181 310 Pfam PF02390 Putative methyltransferase 22 185 5.6E-37 T 14-10-2018 Theos_0413 8051a73f3941a564bc273d5d4dca7181 310 SUPERFAMILY SSF53335 18 189 6.21E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 SUPERFAMILY SSF50156 287 399 7.54E-15 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 Gene3D G3DSA:2.30.42.10 281 404 1.4E-22 T 14-10-2018 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 Pfam PF13180 PDZ domain 288 399 9.1E-16 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 PRINTS PR00834 HtrA/DegQ protease family signature 127 147 5.6E-42 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 PRINTS PR00834 HtrA/DegQ protease family signature 105 117 5.6E-42 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 PRINTS PR00834 HtrA/DegQ protease family signature 169 193 5.6E-42 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 PRINTS PR00834 HtrA/DegQ protease family signature 208 225 5.6E-42 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 PRINTS PR00834 HtrA/DegQ protease family signature 230 247 5.6E-42 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 SMART SM00228 288 392 1.1E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 SUPERFAMILY SSF50494 52 276 2.39E-58 T 14-10-2018 IPR009003 Peptidase S1, PA clan Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 Gene3D G3DSA:2.40.10.120 50 274 7.5E-70 T 14-10-2018 Theos_0524 4a92cb4419e556f415e0e759076e7b5a 405 Pfam PF13365 Trypsin-like peptidase domain 96 237 1.7E-35 T 14-10-2018 Theos_1020 75aaf46d6e036c743574c4990023f855 1725 Gene3D G3DSA:3.40.50.300 945 1068 6.9E-19 T 14-10-2018 Theos_1020 75aaf46d6e036c743574c4990023f855 1725 SMART SM00487 159 395 2.7E-27 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_1020 75aaf46d6e036c743574c4990023f855 1725 Gene3D G3DSA:3.40.50.300 158 372 4.8E-41 T 14-10-2018 Theos_1020 75aaf46d6e036c743574c4990023f855 1725 SUPERFAMILY SSF52540 160 362 6.55E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1020 75aaf46d6e036c743574c4990023f855 1725 SMART SM00490 963 1041 3.6E-16 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1020 75aaf46d6e036c743574c4990023f855 1725 SUPERFAMILY SSF52540 177 1093 1.11E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1020 75aaf46d6e036c743574c4990023f855 1725 Pfam PF00270 DEAD/DEAH box helicase 166 360 8.3E-21 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Theos_1020 75aaf46d6e036c743574c4990023f855 1725 Pfam PF00271 Helicase conserved C-terminal domain 970 1041 1.3E-11 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 SUPERFAMILY SSF53223 3 118 4.7E-33 T 14-10-2018 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 Gene3D G3DSA:3.40.50.720 6 253 1.7E-107 T 14-10-2018 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 120 273 3.1E-69 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 117 3.7E-31 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 254 262 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 200 229 1.3E-74 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 106 127 1.3E-74 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 250 268 1.3E-74 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 71 98 1.3E-74 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 151 171 1.3E-74 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 30 52 1.3E-74 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 277 37.74 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 SUPERFAMILY SSF51735 119 273 2.51E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1484 c5e1ce6256f7ee2c6596663bdb417e7a 282 Gene3D G3DSA:3.40.50.10860 8 270 1.7E-107 T 14-10-2018 Theos_1706 cd290b732832dbc6a1496a8fd1c0e67e 352 SUPERFAMILY SSF55120 13 338 2.16E-88 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_1706 cd290b732832dbc6a1496a8fd1c0e67e 352 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 81 94 - T 14-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 Theos_1706 cd290b732832dbc6a1496a8fd1c0e67e 352 Gene3D G3DSA:3.30.2340.10 171 300 7.6E-89 T 14-10-2018 Theos_1706 cd290b732832dbc6a1496a8fd1c0e67e 352 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 193 335 9.1E-27 T 14-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_1706 cd290b732832dbc6a1496a8fd1c0e67e 352 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 14 171 3.5E-47 T 14-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_1706 cd290b732832dbc6a1496a8fd1c0e67e 352 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 9 340 26.6 T 14-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_1706 cd290b732832dbc6a1496a8fd1c0e67e 352 Gene3D G3DSA:3.30.2350.20 21 335 7.6E-89 T 14-10-2018 Theos_1743 1323b5b00783bb305877840d64f653a2 268 PIRSF PIRSF001359 1 257 2.6E-58 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Theos_1743 1323b5b00783bb305877840d64f653a2 268 SUPERFAMILY SSF51569 7 256 1.2E-66 T 14-10-2018 Theos_1743 1323b5b00783bb305877840d64f653a2 268 Gene3D G3DSA:3.20.20.70 1 267 1.6E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1743 1323b5b00783bb305877840d64f653a2 268 Pfam PF01116 Fructose-bisphosphate aldolase class-II 11 262 7.0E-71 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Theos_0655 f928255ae9f4bf82e149ffbceb0582bd 307 Pfam PF00156 Phosphoribosyl transferase domain 163 245 7.3E-12 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Theos_0655 f928255ae9f4bf82e149ffbceb0582bd 307 SUPERFAMILY SSF53271 3 156 8.5E-56 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_0655 f928255ae9f4bf82e149ffbceb0582bd 307 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 3 119 1.3E-47 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Theos_0655 f928255ae9f4bf82e149ffbceb0582bd 307 Gene3D G3DSA:3.40.50.2020 6 295 5.1E-110 T 14-10-2018 Theos_0655 f928255ae9f4bf82e149ffbceb0582bd 307 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 306 4.8E-106 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Theos_0655 f928255ae9f4bf82e149ffbceb0582bd 307 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 127 142 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 Theos_0655 f928255ae9f4bf82e149ffbceb0582bd 307 Gene3D G3DSA:3.40.50.2020 146 284 5.1E-110 T 14-10-2018 Theos_0655 f928255ae9f4bf82e149ffbceb0582bd 307 SUPERFAMILY SSF53271 86 279 3.36E-41 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_0655 f928255ae9f4bf82e149ffbceb0582bd 307 SMART SM01400 3 119 1.6E-78 T 14-10-2018 Theos_0085 d17a25384219f47278265a6954a0cf1d 138 Gene3D G3DSA:3.90.1010.10 1 138 1.4E-59 T 14-10-2018 Theos_0085 d17a25384219f47278265a6954a0cf1d 138 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 4 137 2.0E-51 T 14-10-2018 Theos_0085 d17a25384219f47278265a6954a0cf1d 138 SUPERFAMILY SSF82649 3 137 4.71E-50 T 14-10-2018 Theos_0085 d17a25384219f47278265a6954a0cf1d 138 Pfam PF01592 NifU-like N terminal domain 8 112 4.6E-25 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 SMART SM00937 59 174 7.2E-54 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 Gene3D G3DSA:3.30.70.1660 277 354 1.7E-18 T 14-10-2018 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 Pfam PF03462 PCRF domain 8 199 1.2E-70 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 223 239 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 SUPERFAMILY SSF75620 8 348 4.19E-130 T 14-10-2018 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 Gene3D G3DSA:1.20.58.410 2 99 3.5E-6 T 14-10-2018 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 Gene3D G3DSA:3.30.160.20 217 276 5.0E-31 T 14-10-2018 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 352 1.8E-142 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 352 37.415 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 Pfam PF00472 RF-1 domain 208 316 4.0E-40 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Theos_0024 e4cfe0ff61fee0d60df58774f4a6e3d3 354 Gene3D G3DSA:3.30.70.1660 103 216 8.6E-45 T 14-10-2018 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 Gene3D G3DSA:1.10.240.10 217 333 4.4E-31 T 14-10-2018 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 Pfam PF00579 tRNA synthetases class I (W and Y) 28 278 8.6E-60 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 1 423 43.169 T 14-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 Pfam PF01479 S4 domain 372 404 3.2E-5 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 Gene3D G3DSA:3.10.290.10 345 422 7.7E-29 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 SUPERFAMILY SSF55174 345 422 1.83E-17 T 14-10-2018 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 Gene3D G3DSA:3.40.50.620 2 216 2.4E-76 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 SUPERFAMILY SSF52374 5 292 2.17E-80 T 14-10-2018 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 1.8E-24 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 177 199 1.8E-24 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 1.8E-24 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 210 222 1.8E-24 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Theos_1602 8e4f44641500f0e8b28ac2a47adc91a6 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 6 275 6.7E-85 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Theos_0971 abc2345d7b147b96f500f8540484701b 517 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 270 277 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Theos_0971 abc2345d7b147b96f500f8540484701b 517 Gene3D G3DSA:3.40.309.10 274 474 6.9E-189 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Theos_0971 abc2345d7b147b96f500f8540484701b 517 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 28 515 1.4E-245 T 14-10-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 Theos_0971 abc2345d7b147b96f500f8540484701b 517 Pfam PF00171 Aldehyde dehydrogenase family 38 501 2.1E-168 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Theos_0971 abc2345d7b147b96f500f8540484701b 517 Gene3D G3DSA:3.40.605.10 41 499 6.9E-189 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_0971 abc2345d7b147b96f500f8540484701b 517 SUPERFAMILY SSF53720 26 505 9.82E-162 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_0971 abc2345d7b147b96f500f8540484701b 517 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 298 309 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Theos_1966 98762193d66bbbe7b9df034e3ee61eb5 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 18 155 3.1E-51 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1966 98762193d66bbbe7b9df034e3ee61eb5 161 SUPERFAMILY SSF52121 10 158 1.83E-56 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1966 98762193d66bbbe7b9df034e3ee61eb5 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 13 158 30.174 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1966 98762193d66bbbe7b9df034e3ee61eb5 161 Gene3D G3DSA:3.40.50.960 7 159 2.8E-55 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1966 98762193d66bbbe7b9df034e3ee61eb5 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 18 154 1.6E-51 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_2182 c4717ceb15ead71027c8125a5a0c02a4 230 Gene3D G3DSA:1.25.40.10 22 146 2.0E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2182 c4717ceb15ead71027c8125a5a0c02a4 230 SUPERFAMILY SSF48452 68 203 1.99E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2182 c4717ceb15ead71027c8125a5a0c02a4 230 Gene3D G3DSA:1.25.40.10 154 228 8.2E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1594 e4271d08cd7b213af7670b01072f4876 437 Gene3D G3DSA:3.40.1080.10 1 180 8.2E-70 T 14-10-2018 Theos_1594 e4271d08cd7b213af7670b01072f4876 437 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 269 420 1.9E-65 T 14-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain Theos_1594 e4271d08cd7b213af7670b01072f4876 437 Gene3D G3DSA:3.30.750.70 183 286 5.5E-42 T 14-10-2018 Theos_1594 e4271d08cd7b213af7670b01072f4876 437 Gene3D G3DSA:3.40.1080.20 288 429 1.2E-65 T 14-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily Theos_1594 e4271d08cd7b213af7670b01072f4876 437 SUPERFAMILY SSF100950 3 220 6.28E-54 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Theos_1594 e4271d08cd7b213af7670b01072f4876 437 SUPERFAMILY SSF100950 187 429 7.54E-70 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Theos_1594 e4271d08cd7b213af7670b01072f4876 437 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 4 176 1.4E-24 T 14-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 Theos_0492 fece3743dedbd3b82b0619fb3eec1a3b 406 Gene3D G3DSA:3.40.1350.30 113 245 3.5E-59 T 14-10-2018 Theos_0492 fece3743dedbd3b82b0619fb3eec1a3b 406 Gene3D G3DSA:3.40.50.150 74 400 3.5E-59 T 14-10-2018 Theos_0492 fece3743dedbd3b82b0619fb3eec1a3b 406 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 242 324 1.8E-7 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 Theos_0492 fece3743dedbd3b82b0619fb3eec1a3b 406 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 331 404 5.6E-10 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 Theos_0492 fece3743dedbd3b82b0619fb3eec1a3b 406 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 337 368 - T 14-10-2018 IPR030390 RNA methyltransferase TrmA, active site Theos_0492 fece3743dedbd3b82b0619fb3eec1a3b 406 SUPERFAMILY SSF53335 75 403 1.29E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0492 fece3743dedbd3b82b0619fb3eec1a3b 406 Gene3D G3DSA:2.40.50.140 1 67 1.8E-7 T 14-10-2018 Theos_0492 fece3743dedbd3b82b0619fb3eec1a3b 406 SUPERFAMILY SSF50249 2 44 1.43E-5 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_2060 aea6e0cb78f93bee27f36da424ce5302 211 Gene3D G3DSA:3.90.10.10 21 114 8.8E-10 T 14-10-2018 Theos_2060 aea6e0cb78f93bee27f36da424ce5302 211 Pfam PF14522 Cytochrome c7 and related cytochrome c 121 211 2.2E-7 T 14-10-2018 IPR029467 C-type polyheme cytochrome OmcB Theos_2060 aea6e0cb78f93bee27f36da424ce5302 211 SUPERFAMILY SSF48695 39 184 9.86E-43 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-30 T 14-10-2018 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.1E-30 T 14-10-2018 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.1E-30 T 14-10-2018 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.1E-30 T 14-10-2018 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 1.1E-30 T 14-10-2018 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 SUPERFAMILY SSF51905 2 316 1.3E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 Gene3D G3DSA:3.50.50.60 4 339 1.3E-158 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 SUPERFAMILY SSF55424 322 442 6.87E-29 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.6E-20 T 14-10-2018 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.6E-20 T 14-10-2018 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 1.6E-20 T 14-10-2018 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 1.6E-20 T 14-10-2018 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 329 430 7.7E-13 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 Gene3D G3DSA:3.50.50.60 115 439 1.3E-158 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0116 4d8f96f3dc1148db16f507c93756eb96 444 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 291 5.0E-64 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Theos_1897 dc473219c5e51cf5ce5c422b81fa639d 183 Gene3D G3DSA:1.10.3210.10 11 151 2.9E-9 T 14-10-2018 Theos_1897 dc473219c5e51cf5ce5c422b81fa639d 183 TIGRFAM TIGR00277 HDIG: HDIG domain 18 88 2.6E-9 T 14-10-2018 IPR006675 HDIG domain Theos_1897 dc473219c5e51cf5ce5c422b81fa639d 183 SUPERFAMILY SSF109604 17 154 2.17E-18 T 14-10-2018 Theos_1897 dc473219c5e51cf5ce5c422b81fa639d 183 Pfam PF01966 HD domain 22 88 5.6E-8 T 14-10-2018 IPR006674 HD domain Theos_1897 dc473219c5e51cf5ce5c422b81fa639d 183 SMART SM00471 16 121 0.0039 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 SUPERFAMILY SSF50715 338 544 1.36E-60 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 Gene3D G3DSA:2.40.240.10 346 459 5.4E-33 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 31 42 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 338 525 2.2E-46 T 14-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 Gene3D G3DSA:2.40.240.10 460 544 1.8E-28 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 Gene3D G3DSA:3.40.50.620 5 341 1.6E-129 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 SUPERFAMILY SSF52374 25 341 5.89E-91 T 14-10-2018 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 25 335 7.0E-100 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 40 1.2E-10 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 PRINTS PR00987 Glutamyl-tRNA synthetase signature 202 212 1.2E-10 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 PRINTS PR00987 Glutamyl-tRNA synthetase signature 57 70 1.2E-10 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 53 1.2E-10 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Theos_0775 b9120abc91b2b359affbaa4487cb51a8 548 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 26 546 4.3E-192 T 14-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 PIRSF PIRSF002158 3 276 8.8E-105 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.861 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 127 251 4.6E-54 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 Gene3D G3DSA:4.10.950.10 197 276 6.7E-37 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 Gene3D G3DSA:2.40.50.140 1 115 4.1E-53 T 14-10-2018 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 SMART SM01382 125 253 6.7E-85 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 3.7E-137 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 2.8E-34 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 SUPERFAMILY SSF50249 3 125 6.17E-55 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0280 1b5c312b416e193c94656420e3a411d7 276 Gene3D G3DSA:2.30.30.30 119 196 6.3E-31 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 SUPERFAMILY SSF50104 127 272 1.87E-59 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Theos_0280 1b5c312b416e193c94656420e3a411d7 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0280 1b5c312b416e193c94656420e3a411d7 276 SMART SM01383 42 119 2.3E-47 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1628 82ca288f28318764e8aa60937ffa8c2a 317 Pfam PF00005 ABC transporter 18 156 4.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1628 82ca288f28318764e8aa60937ffa8c2a 317 SUPERFAMILY SSF52540 5 235 3.33E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1628 82ca288f28318764e8aa60937ffa8c2a 317 Gene3D G3DSA:3.40.50.300 15 254 4.3E-71 T 14-10-2018 Theos_1628 82ca288f28318764e8aa60937ffa8c2a 317 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1628 82ca288f28318764e8aa60937ffa8c2a 317 SMART SM00382 23 214 8.0E-22 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0011 505af82dbe155436f296e4100ea60005 616 SUPERFAMILY SSF53323 4 249 5.1E-16 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Theos_0011 505af82dbe155436f296e4100ea60005 616 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 243 475 1.3E-59 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Theos_0011 505af82dbe155436f296e4100ea60005 616 Gene3D G3DSA:3.40.50.920 499 604 2.0E-20 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_0011 505af82dbe155436f296e4100ea60005 616 Gene3D G3DSA:3.40.920.10 2 217 3.5E-14 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Theos_0011 505af82dbe155436f296e4100ea60005 616 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 211 1.4E-38 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Theos_0011 505af82dbe155436f296e4100ea60005 616 SUPERFAMILY SSF52922 500 604 1.44E-15 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_0011 505af82dbe155436f296e4100ea60005 616 Gene3D G3DSA:3.40.50.970 223 416 4.2E-66 T 14-10-2018 Theos_0011 505af82dbe155436f296e4100ea60005 616 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 3 597 3.4E-174 T 14-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 Theos_0011 505af82dbe155436f296e4100ea60005 616 SUPERFAMILY SSF52518 231 490 2.67E-59 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_0260 aa1ff8b5cc3065f3064193dc57a188ca 113 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 107 2.7E-32 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Theos_0260 aa1ff8b5cc3065f3064193dc57a188ca 113 Pfam PF02410 Ribosomal silencing factor during starvation 13 107 3.6E-25 T 14-10-2018 Theos_0260 aa1ff8b5cc3065f3064193dc57a188ca 113 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 108 22.72 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Theos_0260 aa1ff8b5cc3065f3064193dc57a188ca 113 SUPERFAMILY SSF81301 8 111 2.13E-32 T 14-10-2018 Theos_0260 aa1ff8b5cc3065f3064193dc57a188ca 113 Gene3D G3DSA:3.30.460.10 1 111 7.4E-34 T 14-10-2018 Theos_2418 7c57f32c579d27272115afa3c81c6c35 1099 Pfam PF04465 Protein of unknown function (DUF499) 291 932 2.9E-31 T 14-10-2018 IPR007555 Protein of unknown function DUF499 Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 Gene3D G3DSA:3.60.15.10 29 469 3.3E-175 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 PIRSF PIRSF004803 19 572 2.1E-217 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 Pfam PF12706 Beta-lactamase superfamily domain 83 198 3.7E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 387 425 1.2E-5 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 27 569 1.8E-154 T 14-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 SUPERFAMILY SSF56281 27 449 4.99E-84 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 Gene3D G3DSA:3.40.50.10710 234 383 3.3E-175 T 14-10-2018 Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 SMART SM00849 39 241 2.6E-15 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 Hamap MF_01491 Ribonuclease J [rnj]. 22 572 41.012 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 Theos_1504 8f6a3dbd1d0a9d94eab0411e4b6068d7 583 Gene3D G3DSA:3.10.20.580 474 571 1.1E-31 T 14-10-2018 Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 SUPERFAMILY SSF54999 3 99 2.22E-35 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 Gene3D G3DSA:3.30.70.600 1 105 6.0E-39 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 14-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 SMART SM01403 5 99 1.5E-52 T 14-10-2018 IPR027486 Ribosomal protein S10 domain Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 26.037 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 Pfam PF00338 Ribosomal protein S10p/S20e 5 99 1.2E-33 T 14-10-2018 IPR027486 Ribosomal protein S10 domain Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 3 99 1.5E-43 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 5.3E-19 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 5.3E-19 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0276 f33c03db085d8a56bc6416c49f0e4693 105 PRINTS PR00971 Ribosomal protein S10 family signature 59 73 5.3E-19 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0869 e7d8cdec965502231d8b74fc13d4b6c4 125 SMART SM00450 28 122 1.1E-29 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0869 e7d8cdec965502231d8b74fc13d4b6c4 125 SUPERFAMILY SSF52821 15 125 2.23E-37 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0869 e7d8cdec965502231d8b74fc13d4b6c4 125 Pfam PF00581 Rhodanese-like domain 30 117 1.6E-19 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0869 e7d8cdec965502231d8b74fc13d4b6c4 125 Gene3D G3DSA:3.40.250.10 31 125 4.8E-34 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0869 e7d8cdec965502231d8b74fc13d4b6c4 125 ProSitePatterns PS00380 Rhodanese signature 1. 52 63 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 Theos_1560 c13735ddfc03fbc2bca79a4174e3ed49 225 Pfam PF02585 GlcNAc-PI de-N-acetylase 1 122 4.6E-24 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 Theos_1560 c13735ddfc03fbc2bca79a4174e3ed49 225 SUPERFAMILY SSF102588 1 216 1.16E-45 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_1560 c13735ddfc03fbc2bca79a4174e3ed49 225 Gene3D G3DSA:3.40.50.10320 1 213 2.5E-49 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 Theos_1785 f7d7e3f7b2b0ce001dbabec9e44f5d08 135 PIRSF PIRSF036659 1 135 3.3E-39 T 14-10-2018 IPR012187 Disulphide bond formation protein BdbC Theos_1785 f7d7e3f7b2b0ce001dbabec9e44f5d08 135 Pfam PF02600 Disulfide bond formation protein DsbB 7 101 5.3E-9 T 14-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 Theos_1785 f7d7e3f7b2b0ce001dbabec9e44f5d08 135 Gene3D G3DSA:1.20.1550.10 1 115 2.4E-9 T 14-10-2018 IPR023380 DsbB-like superfamily Theos_1785 f7d7e3f7b2b0ce001dbabec9e44f5d08 135 SUPERFAMILY SSF158442 9 127 6.28E-24 T 14-10-2018 IPR023380 DsbB-like superfamily Theos_1462 1821250112b4ef90c95df2e1874c8665 293 SUPERFAMILY SSF51366 17 267 1.22E-68 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Theos_1462 1821250112b4ef90c95df2e1874c8665 293 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 3 293 53.81 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_1462 1821250112b4ef90c95df2e1874c8665 293 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 8 293 3.0E-153 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_1462 1821250112b4ef90c95df2e1874c8665 293 Gene3D G3DSA:3.20.20.70 1 293 1.4E-156 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1462 1821250112b4ef90c95df2e1874c8665 293 PIRSF PIRSF029271 1 293 5.4E-158 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_1462 1821250112b4ef90c95df2e1874c8665 293 Pfam PF01680 SOR/SNZ family 6 211 3.1E-112 T 14-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_1462 1821250112b4ef90c95df2e1874c8665 293 ProSitePatterns PS01235 PdxS/SNZ family signature. 204 222 - T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_0248 52fdfa9b1f4556eb992947d90a592b2f 543 SUPERFAMILY SSF52540 6 540 3.12E-206 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0248 52fdfa9b1f4556eb992947d90a592b2f 543 Gene3D G3DSA:3.40.50.300 5 424 1.1E-175 T 14-10-2018 Theos_0248 52fdfa9b1f4556eb992947d90a592b2f 543 Pfam PF01268 Formate--tetrahydrofolate ligase 5 541 6.8E-221 T 14-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Theos_0248 52fdfa9b1f4556eb992947d90a592b2f 543 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 317 328 - T 14-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Theos_0248 52fdfa9b1f4556eb992947d90a592b2f 543 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 92 102 - T 14-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Theos_0248 52fdfa9b1f4556eb992947d90a592b2f 543 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 3 543 43.776 T 14-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Theos_0248 52fdfa9b1f4556eb992947d90a592b2f 543 Gene3D G3DSA:3.10.410.10 429 518 8.5E-29 T 14-10-2018 Theos_0248 52fdfa9b1f4556eb992947d90a592b2f 543 Gene3D G3DSA:3.30.1510.10 118 236 1.1E-175 T 14-10-2018 Theos_1399 6174b7a63d9331fc08d5d9977c6a787a 248 SMART SM00479 71 235 1.3E-35 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Theos_1399 6174b7a63d9331fc08d5d9977c6a787a 248 Gene3D G3DSA:3.30.420.10 68 231 2.5E-39 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Theos_1399 6174b7a63d9331fc08d5d9977c6a787a 248 Pfam PF00929 Exonuclease 74 225 1.3E-24 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Theos_1399 6174b7a63d9331fc08d5d9977c6a787a 248 SUPERFAMILY SSF53098 73 229 3.64E-40 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_1046 ab8e2ca4eb5e8b84d90a99172e6c8afc 684 Pfam PF02421 Ferrous iron transport protein B 19 163 1.7E-47 T 14-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 Theos_1046 ab8e2ca4eb5e8b84d90a99172e6c8afc 684 Gene3D G3DSA:3.40.50.300 17 180 4.6E-34 T 14-10-2018 Theos_1046 ab8e2ca4eb5e8b84d90a99172e6c8afc 684 SUPERFAMILY SSF52540 20 187 9.96E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1046 ab8e2ca4eb5e8b84d90a99172e6c8afc 684 Pfam PF07670 Nucleoside recognition 503 659 1.5E-22 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Theos_1046 ab8e2ca4eb5e8b84d90a99172e6c8afc 684 Pfam PF07670 Nucleoside recognition 342 429 9.5E-8 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Theos_1046 ab8e2ca4eb5e8b84d90a99172e6c8afc 684 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 23 654 7.9E-142 T 14-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 Theos_1046 ab8e2ca4eb5e8b84d90a99172e6c8afc 684 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 40 58 5.2E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_1046 ab8e2ca4eb5e8b84d90a99172e6c8afc 684 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 19 39 5.2E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_1046 ab8e2ca4eb5e8b84d90a99172e6c8afc 684 Pfam PF07664 Ferrous iron transport protein B C terminus 445 496 7.2E-13 T 14-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 Theos_1075 cc092cdafd27db6d2cacfada2f30ada3 380 SUPERFAMILY SSF53474 36 379 1.37E-92 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1075 cc092cdafd27db6d2cacfada2f30ada3 380 Gene3D G3DSA:3.40.50.1820 39 380 1.3E-123 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1075 cc092cdafd27db6d2cacfada2f30ada3 380 Pfam PF00561 alpha/beta hydrolase fold 70 366 1.8E-25 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Theos_1075 cc092cdafd27db6d2cacfada2f30ada3 380 PRINTS PR00111 Alpha/beta hydrolase fold signature 182 195 1.3E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Theos_1075 cc092cdafd27db6d2cacfada2f30ada3 380 PRINTS PR00111 Alpha/beta hydrolase fold signature 196 209 1.3E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Theos_1075 cc092cdafd27db6d2cacfada2f30ada3 380 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 29 380 31.17 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Theos_1075 cc092cdafd27db6d2cacfada2f30ada3 380 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 41 379 3.4E-122 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Theos_1075 cc092cdafd27db6d2cacfada2f30ada3 380 PIRSF PIRSF000443 30 380 2.3E-108 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Theos_1145 1f3eac94515cc17b736b30083ba775f2 277 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 119 134 - T 14-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Theos_1145 1f3eac94515cc17b736b30083ba775f2 277 Pfam PF00494 Squalene/phytoene synthase 13 260 1.8E-62 T 14-10-2018 Theos_1145 1f3eac94515cc17b736b30083ba775f2 277 Gene3D G3DSA:1.10.600.10 1 272 3.2E-77 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Theos_1145 1f3eac94515cc17b736b30083ba775f2 277 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 148 173 - T 14-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Theos_1145 1f3eac94515cc17b736b30083ba775f2 277 SUPERFAMILY SSF48576 4 273 3.6E-72 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Theos_1841 1af402ffabf171bae8759f8b48cb8f4c 172 SUPERFAMILY SSF159234 22 161 9.55E-21 T 14-10-2018 IPR035930 FomD-like superfamily Theos_1841 1af402ffabf171bae8759f8b48cb8f4c 172 Pfam PF04167 Protein of unknown function (DUF402) 62 126 1.6E-10 T 14-10-2018 IPR007295 Domain of unknown function DUF402 Theos_1841 1af402ffabf171bae8759f8b48cb8f4c 172 Gene3D G3DSA:2.40.380.10 59 164 1.4E-9 T 14-10-2018 IPR035930 FomD-like superfamily Theos_1470 85809fc58b0acd62c7e8120276fc9d2f 272 SUPERFAMILY SSF51658 8 269 2.75E-68 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily Theos_1470 85809fc58b0acd62c7e8120276fc9d2f 272 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 206 222 - T 14-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 Theos_1470 85809fc58b0acd62c7e8120276fc9d2f 272 Gene3D G3DSA:3.20.20.150 6 272 1.4E-91 T 14-10-2018 Theos_1470 85809fc58b0acd62c7e8120276fc9d2f 272 Pfam PF01261 Xylose isomerase-like TIM barrel 24 230 2.7E-26 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Theos_1470 85809fc58b0acd62c7e8120276fc9d2f 272 SMART SM00518 6 270 7.7E-63 T 14-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Theos_1470 85809fc58b0acd62c7e8120276fc9d2f 272 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 8 270 6.5E-61 T 14-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Theos_1470 85809fc58b0acd62c7e8120276fc9d2f 272 Hamap MF_00152 Probable endonuclease 4 [nfo]. 5 270 33.018 T 14-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Theos_1607 c553384e47dafeda389c5aad33af2afe 643 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 331 626 5.6E-47 T 14-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal Theos_1607 c553384e47dafeda389c5aad33af2afe 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 81 107 2.9E-40 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1607 c553384e47dafeda389c5aad33af2afe 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 2.9E-40 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1607 c553384e47dafeda389c5aad33af2afe 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 273 293 2.9E-40 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1607 c553384e47dafeda389c5aad33af2afe 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 131 148 2.9E-40 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1607 c553384e47dafeda389c5aad33af2afe 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 243 263 2.9E-40 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1607 c553384e47dafeda389c5aad33af2afe 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 293 309 2.9E-40 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1607 c553384e47dafeda389c5aad33af2afe 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 209 235 2.9E-40 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1607 c553384e47dafeda389c5aad33af2afe 643 Pfam PF01578 Cytochrome C assembly protein 90 294 8.3E-31 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 Theos_0360 972bfea21a8ccbb94978929f05f74046 173 Pfam PF00156 Phosphoribosyl transferase domain 34 159 1.5E-18 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Theos_0360 972bfea21a8ccbb94978929f05f74046 173 Gene3D G3DSA:3.40.50.2020 1 170 1.2E-50 T 14-10-2018 Theos_0360 972bfea21a8ccbb94978929f05f74046 173 SUPERFAMILY SSF53271 10 158 7.21E-28 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_2237 e0a4f4ad90a105b992674136dbc2058c 330 Gene3D G3DSA:3.40.1000.10 51 194 1.0E-9 T 14-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 755 891 4.5E-40 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 Pfam PF02779 Transketolase, pyrimidine binding domain 556 751 5.5E-62 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 7 890 7.5E-301 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 SMART SM00861 557 750 2.6E-54 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 SUPERFAMILY SSF52518 119 499 2.42E-72 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 Gene3D G3DSA:3.40.50.12470 515 772 1.5E-158 T 14-10-2018 Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 PIRSF PIRSF000157 2 892 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 Gene3D G3DSA:3.40.50.11610 693 889 1.5E-158 T 14-10-2018 Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 SUPERFAMILY SSF52922 774 873 4.19E-5 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 Gene3D G3DSA:1.10.287.1150 58 130 6.0E-13 T 14-10-2018 Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 Pfam PF00676 Dehydrogenase E1 component 176 487 2.3E-45 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 SUPERFAMILY SSF52518 539 757 4.81E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 Gene3D G3DSA:3.40.50.970 131 486 1.7E-129 T 14-10-2018 Theos_0133 650d521b205a6d0b05dd8bd4f4fa0253 892 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 7 36 2.0E-8 T 14-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Theos_1615 96927b2a54530db60669241807c2627a 427 SUPERFAMILY SSF56524 68 312 4.58E-72 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 SUPERFAMILY SSF81296 282 396 4.06E-30 T 14-10-2018 IPR014756 Immunoglobulin E-set Theos_1615 96927b2a54530db60669241807c2627a 427 Gene3D G3DSA:2.60.40.650 281 407 5.5E-46 T 14-10-2018 Theos_1615 96927b2a54530db60669241807c2627a 427 Gene3D G3DSA:3.90.420.10 27 280 2.5E-84 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 Pfam PF00174 Oxidoreductase molybdopterin binding domain 94 256 1.4E-52 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 279 392 1.6E-15 T 14-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 82 98 3.1E-23 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 224 237 3.1E-23 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 134 145 3.1E-23 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 240 253 3.1E-23 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 207 223 3.1E-23 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 317 329 3.1E-23 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_1615 96927b2a54530db60669241807c2627a 427 TIGRFAM TIGR04555 sulfite_DH_soxC: sulfite dehydrogenase 3 404 5.7E-175 T 14-10-2018 IPR030835 Sulfite dehydrogenase SoxC Theos_0563 d2b7d0dfaa16dadd3436cf6eed944839 298 Gene3D G3DSA:1.20.272.10 172 294 1.6E-25 T 14-10-2018 Theos_0563 d2b7d0dfaa16dadd3436cf6eed944839 298 SUPERFAMILY SSF48019 172 290 3.15E-21 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Theos_0563 d2b7d0dfaa16dadd3436cf6eed944839 298 Gene3D G3DSA:1.10.8.60 107 168 6.5E-6 T 14-10-2018 Theos_0563 d2b7d0dfaa16dadd3436cf6eed944839 298 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 55 290 3.6E-34 T 14-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 Theos_0563 d2b7d0dfaa16dadd3436cf6eed944839 298 SUPERFAMILY SSF52540 48 166 4.06E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0312 9cf888e61a21dd13f7d7e4d92782553e 211 Gene3D G3DSA:3.40.50.720 74 211 5.9E-46 T 14-10-2018 Theos_0312 9cf888e61a21dd13f7d7e4d92782553e 211 Pfam PF06971 Putative DNA-binding protein N-terminus 2 50 2.7E-19 T 14-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 Theos_0312 9cf888e61a21dd13f7d7e4d92782553e 211 Gene3D G3DSA:1.10.10.10 1 73 5.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0312 9cf888e61a21dd13f7d7e4d92782553e 211 Pfam PF02629 CoA binding domain 79 174 1.4E-19 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Theos_0312 9cf888e61a21dd13f7d7e4d92782553e 211 SUPERFAMILY SSF51735 78 199 3.21E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0312 9cf888e61a21dd13f7d7e4d92782553e 211 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 204 34.357 T 14-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 Theos_0312 9cf888e61a21dd13f7d7e4d92782553e 211 SUPERFAMILY SSF46785 4 76 2.61E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0312 9cf888e61a21dd13f7d7e4d92782553e 211 SMART SM00881 76 175 1.1E-13 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Theos_0422 738a242a67e712509393e6fc9427c0c2 180 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 47 156 1.2E-7 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Theos_0422 738a242a67e712509393e6fc9427c0c2 180 Pfam PF00890 FAD binding domain 3 34 2.3E-8 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_0422 738a242a67e712509393e6fc9427c0c2 180 SUPERFAMILY SSF51905 2 174 3.18E-31 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0422 738a242a67e712509393e6fc9427c0c2 180 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 34 49 4.0E-14 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0422 738a242a67e712509393e6fc9427c0c2 180 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 4.0E-14 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0422 738a242a67e712509393e6fc9427c0c2 180 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 55 65 4.0E-14 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0422 738a242a67e712509393e6fc9427c0c2 180 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 21 8.3E-7 T 14-10-2018 Theos_0422 738a242a67e712509393e6fc9427c0c2 180 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 123 145 8.3E-7 T 14-10-2018 Theos_0422 738a242a67e712509393e6fc9427c0c2 180 Gene3D G3DSA:3.50.50.60 1 173 1.1E-67 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0921 d416ea7c628616ed99f21009b9035d40 92 Pfam PF02033 Ribosome-binding factor A 8 88 2.6E-15 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Theos_0921 d416ea7c628616ed99f21009b9035d40 92 SUPERFAMILY SSF89919 7 89 1.57E-19 T 14-10-2018 IPR023799 Ribosome-binding factor A domain superfamily Theos_0921 d416ea7c628616ed99f21009b9035d40 92 Gene3D G3DSA:3.30.300.20 1 92 2.5E-22 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_0921 d416ea7c628616ed99f21009b9035d40 92 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 53 4.0E-4 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Theos_0921 d416ea7c628616ed99f21009b9035d40 92 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 92 18.137 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Theos_1150 890b0efda7b3efd72d06f1c3981f1dbd 215 SMART SM00563 38 143 2.9E-18 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Theos_1150 890b0efda7b3efd72d06f1c3981f1dbd 215 SUPERFAMILY SSF69593 12 187 8.89E-17 T 14-10-2018 Theos_1150 890b0efda7b3efd72d06f1c3981f1dbd 215 Pfam PF01553 Acyltransferase 34 139 5.5E-12 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Theos_0573 1a2c9f593a568035a2aca88ccb686a28 446 Gene3D G3DSA:3.30.465.40 3 220 8.4E-61 T 14-10-2018 Theos_0573 1a2c9f593a568035a2aca88ccb686a28 446 SUPERFAMILY SSF56176 3 205 3.32E-61 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Theos_0573 1a2c9f593a568035a2aca88ccb686a28 446 Pfam PF02913 FAD linked oxidases, C-terminal domain 205 443 8.1E-68 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Theos_0573 1a2c9f593a568035a2aca88ccb686a28 446 Pfam PF01565 FAD binding domain 36 173 6.0E-42 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Theos_0573 1a2c9f593a568035a2aca88ccb686a28 446 Gene3D G3DSA:3.30.70.2740 323 403 2.1E-15 T 14-10-2018 Theos_0573 1a2c9f593a568035a2aca88ccb686a28 446 SUPERFAMILY SSF55103 208 445 3.43E-65 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Theos_0573 1a2c9f593a568035a2aca88ccb686a28 446 Gene3D G3DSA:1.10.45.10 404 444 3.0E-14 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Theos_2395 a66dcc61ab702a96d7c9694f729489f4 478 Gene3D G3DSA:1.10.3720.10 246 478 3.9E-10 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2395 a66dcc61ab702a96d7c9694f729489f4 478 Gene3D G3DSA:1.10.3720.10 1 228 2.9E-19 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2395 a66dcc61ab702a96d7c9694f729489f4 478 SUPERFAMILY SSF161098 244 471 2.18E-15 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2395 a66dcc61ab702a96d7c9694f729489f4 478 SUPERFAMILY SSF161098 7 224 9.29E-14 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1820 d29fe859a33724b1b6a366c300862c72 376 Pfam PF13484 4Fe-4S double cluster binding domain 182 246 1.2E-18 T 14-10-2018 Theos_1820 d29fe859a33724b1b6a366c300862c72 376 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 183 194 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1820 d29fe859a33724b1b6a366c300862c72 376 SUPERFAMILY SSF48371 297 359 3.53E-6 T 14-10-2018 IPR016024 Armadillo-type fold Theos_1820 d29fe859a33724b1b6a366c300862c72 376 SUPERFAMILY SSF46548 152 246 2.88E-16 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Theos_1820 d29fe859a33724b1b6a366c300862c72 376 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 21 333 2.5E-79 T 14-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 Theos_1820 d29fe859a33724b1b6a366c300862c72 376 Pfam PF08331 Domain of unknown function (DUF1730) 56 129 2.5E-11 T 14-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 Theos_1820 d29fe859a33724b1b6a366c300862c72 376 Gene3D G3DSA:1.25.10.10 284 369 1.9E-6 T 14-10-2018 IPR011989 Armadillo-like helical Theos_1590 32d41cfdc96351f62609e0af88bb71b4 278 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 275 13.695 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Theos_1590 32d41cfdc96351f62609e0af88bb71b4 278 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 2 268 2.8E-54 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Theos_1590 32d41cfdc96351f62609e0af88bb71b4 278 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 1 234 1.1E-38 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Theos_0259 7a9469a736b4ecab0bee60e25a208520 365 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 66 208 1.3E-28 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain Theos_0259 7a9469a736b4ecab0bee60e25a208520 365 Gene3D G3DSA:1.10.260.150 50 276 1.7E-43 T 14-10-2018 Theos_0259 7a9469a736b4ecab0bee60e25a208520 365 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 66 208 1.8E-30 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain Theos_1257 8207290786be424c463f1d6fe3dcc106 351 Gene3D G3DSA:3.40.190.10 135 347 1.9E-108 T 14-10-2018 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 Pfam PF13416 Bacterial extracellular solute-binding protein 44 312 1.4E-34 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_1257 8207290786be424c463f1d6fe3dcc106 351 PIRSF PIRSF019574 1 351 4.1E-100 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 35 51 5.9E-39 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 51 72 5.9E-39 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 297 323 5.9E-39 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 95 108 5.9E-39 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 126 142 5.9E-39 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 79 93 5.9E-39 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 170 189 5.9E-39 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 252 271 5.9E-39 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 SUPERFAMILY SSF53850 30 349 9.51E-86 T 14-10-2018 Theos_1257 8207290786be424c463f1d6fe3dcc106 351 Gene3D G3DSA:3.40.190.10 34 319 1.9E-108 T 14-10-2018 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 Gene3D G3DSA:3.30.310.50 358 434 3.5E-23 T 14-10-2018 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 167 186 2.4E-10 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 2.4E-10 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 227 242 2.4E-10 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 431 42.579 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 SUPERFAMILY SSF53738 1 160 7.46E-42 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 428 3.7E-163 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 Gene3D G3DSA:3.40.120.10 250 327 2.8E-58 T 14-10-2018 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 247 4.9E-13 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 Gene3D G3DSA:3.40.120.10 1 146 1.6E-46 T 14-10-2018 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 SUPERFAMILY SSF53738 153 249 1.1E-24 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 252 354 1.8E-29 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 SUPERFAMILY SSF53738 251 353 1.02E-26 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 Gene3D G3DSA:3.40.120.10 167 347 2.8E-58 T 14-10-2018 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 361 425 3.7E-13 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 134 1.6E-42 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_0894 60ff9dd56e7eb12da2a05b81b46929aa 439 SUPERFAMILY SSF55957 346 433 6.41E-21 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 SUPERFAMILY SSF116734 220 389 2.09E-67 T 14-10-2018 Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 89 95 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 Pfam PF12950 TaqI-like C-terminal specificity domain 267 383 8.2E-12 T 14-10-2018 IPR025931 TaqI-like C-terminal specificity domain Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 Gene3D G3DSA:3.90.220.10 220 389 2.7E-65 T 14-10-2018 IPR023135 N6 adenine-specific DNA methyltransferase, TaqI class, C-terminal Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 SUPERFAMILY SSF53335 9 197 2.16E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 86 98 2.5E-16 T 14-10-2018 Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 6 22 2.5E-16 T 14-10-2018 Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 124 148 2.5E-16 T 14-10-2018 Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 31 45 2.5E-16 T 14-10-2018 Theos_1569 f4c07785aa74b55d811760b7c968ff65 401 Gene3D G3DSA:3.40.50.150 9 207 1.2E-40 T 14-10-2018 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 112 139 9.0E-61 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 90 112 9.0E-61 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 9.0E-61 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 258 283 9.0E-61 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 39 51 9.0E-61 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 236 258 9.0E-61 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 Gene3D G3DSA:3.40.50.170 89 285 6.4E-79 T 14-10-2018 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 SUPERFAMILY SSF55021 5 86 1.02E-17 T 14-10-2018 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 Pfam PF00551 Formyl transferase 89 266 1.6E-40 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 SUPERFAMILY SSF53328 89 284 2.09E-60 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 284 47.611 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 Pfam PF01842 ACT domain 5 60 5.3E-11 T 14-10-2018 IPR002912 ACT domain Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 PIRSF PIRSF036480 1 285 2.0E-113 T 14-10-2018 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 Gene3D G3DSA:3.30.70.260 1 88 4.9E-32 T 14-10-2018 Theos_0523 a879bb612140a124683bd9f456dfcf9c 285 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 284 6.2E-122 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Theos_0940 d034924a7d665218dc35643945f66b61 171 Pfam PF03602 Conserved hypothetical protein 95 2 152 3.5E-29 T 14-10-2018 Theos_0940 d034924a7d665218dc35643945f66b61 171 SUPERFAMILY SSF53335 2 168 8.66E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0940 d034924a7d665218dc35643945f66b61 171 PIRSF PIRSF004553 1 171 6.4E-32 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 Theos_0940 d034924a7d665218dc35643945f66b61 171 Gene3D G3DSA:3.40.50.150 1 171 5.3E-46 T 14-10-2018 Theos_1446 8a8e47b1a51fe4a4b6b0e8d795443102 310 SUPERFAMILY SSF51658 41 277 1.09E-19 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily Theos_1446 8a8e47b1a51fe4a4b6b0e8d795443102 310 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 2 282 5.3E-52 T 14-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 Theos_1446 8a8e47b1a51fe4a4b6b0e8d795443102 310 Pfam PF03851 UV-endonuclease UvdE 4 245 5.3E-48 T 14-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 Theos_1446 8a8e47b1a51fe4a4b6b0e8d795443102 310 Gene3D G3DSA:3.20.20.150 1 278 9.4E-100 T 14-10-2018 Theos_0936 7dd45464b607088e42c700b2f29ef51c 323 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 137 243 3.1E-23 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Theos_0936 7dd45464b607088e42c700b2f29ef51c 323 Gene3D G3DSA:3.100.10.20 8 97 1.9E-25 T 14-10-2018 Theos_0936 7dd45464b607088e42c700b2f29ef51c 323 Gene3D G3DSA:1.20.120.920 98 294 6.3E-69 T 14-10-2018 Theos_0936 7dd45464b607088e42c700b2f29ef51c 323 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 11 276 5.7E-108 T 14-10-2018 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 Theos_0936 7dd45464b607088e42c700b2f29ef51c 323 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 11 267 18.269 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Theos_0936 7dd45464b607088e42c700b2f29ef51c 323 Pfam PF01867 CRISPR associated protein Cas1 129 229 1.8E-8 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 SUPERFAMILY SSF54849 136 201 2.29E-23 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 2.3E-104 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 Hamap MF_00600 60 kDa chaperonin [groL]. 1 541 41.94 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 SUPERFAMILY SSF52029 182 374 3.14E-83 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 528 4.7E-256 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 SUPERFAMILY SSF48592 6 522 5.27E-82 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 Gene3D G3DSA:3.30.260.10 135 408 4.2E-235 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 Gene3D G3DSA:1.10.560.10 7 522 4.2E-235 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 Gene3D G3DSA:3.50.7.10 190 370 4.2E-235 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 PRINTS PR00298 60kDa chaperonin signature 26 52 9.5E-72 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 PRINTS PR00298 60kDa chaperonin signature 396 417 9.5E-72 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 PRINTS PR00298 60kDa chaperonin signature 82 109 9.5E-72 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 PRINTS PR00298 60kDa chaperonin signature 266 289 9.5E-72 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Theos_0027 1259ccda9587148c6e4e95ffe1256287 543 PRINTS PR00298 60kDa chaperonin signature 348 373 9.5E-72 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Theos_0102 8aeab2335dc22111b620b1a294c8b404 228 SUPERFAMILY SSF52540 1 221 1.15E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0102 8aeab2335dc22111b620b1a294c8b404 228 Pfam PF00005 ABC transporter 32 168 3.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0102 8aeab2335dc22111b620b1a294c8b404 228 Gene3D G3DSA:3.40.50.300 1 227 1.0E-64 T 14-10-2018 Theos_0102 8aeab2335dc22111b620b1a294c8b404 228 SMART SM00382 29 215 3.6E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0102 8aeab2335dc22111b620b1a294c8b404 228 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 345 358 3.1E-12 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 261 272 3.1E-12 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 234 243 3.1E-12 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00097 Anthranilate synthase component II signature 234 243 4.4E-7 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00097 Anthranilate synthase component II signature 261 272 4.4E-7 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00097 Anthranilate synthase component II signature 345 358 4.4E-7 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 Pfam PF00117 Glutamine amidotransferase class-I 194 367 7.4E-42 T 14-10-2018 IPR017926 Glutamine amidotransferase Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 SMART SM01097 6 136 3.6E-86 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 8 371 7.0E-145 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 SUPERFAMILY SSF52317 168 372 3.06E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 Gene3D G3DSA:3.50.30.20 5 148 1.3E-55 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 Gene3D G3DSA:3.40.50.880 165 374 6.7E-63 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 192 206 9.6E-37 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 231 245 9.6E-37 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 303 314 9.6E-37 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 278 295 9.6E-37 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 261 277 9.6E-37 T 14-10-2018 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 6 374 47.568 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 SUPERFAMILY SSF52021 7 141 1.44E-54 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0125 5ca4e5c1334841fb97d22a257b9813da 391 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 8 135 4.7E-51 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_2431 72a56090c4e3ecce692f27cd5506b86e 204 Gene3D G3DSA:3.40.50.880 1 200 1.3E-69 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_2431 72a56090c4e3ecce692f27cd5506b86e 204 SUPERFAMILY SSF52317 4 196 5.81E-40 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_2431 72a56090c4e3ecce692f27cd5506b86e 204 Pfam PF07722 Peptidase C26 2 187 4.6E-60 T 14-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 Theos_2213 0f12219b8f9162eee9ce62bb48d09f44 321 Gene3D G3DSA:3.90.180.10 18 307 1.2E-65 T 14-10-2018 Theos_2213 0f12219b8f9162eee9ce62bb48d09f44 321 Pfam PF02558 Ketopantoate reductase PanE/ApbA 161 204 4.3E-5 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain Theos_2213 0f12219b8f9162eee9ce62bb48d09f44 321 SUPERFAMILY SSF50129 1 168 7.16E-45 T 14-10-2018 IPR011032 GroES-like superfamily Theos_2213 0f12219b8f9162eee9ce62bb48d09f44 321 Pfam PF00107 Zinc-binding dehydrogenase 212 281 5.6E-11 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Theos_2213 0f12219b8f9162eee9ce62bb48d09f44 321 Gene3D G3DSA:3.40.50.720 146 266 1.2E-65 T 14-10-2018 Theos_2213 0f12219b8f9162eee9ce62bb48d09f44 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 127 2.3E-27 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Theos_2213 0f12219b8f9162eee9ce62bb48d09f44 321 SUPERFAMILY SSF51735 137 282 7.48E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0140 207c5eb1172428402d313db4dcb16201 238 Gene3D G3DSA:3.40.1280.10 73 235 4.4E-50 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Theos_0140 207c5eb1172428402d313db4dcb16201 238 Gene3D G3DSA:3.30.1330.30 1 68 3.0E-5 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like Theos_0140 207c5eb1172428402d313db4dcb16201 238 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 232 2.0E-61 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 Theos_0140 207c5eb1172428402d313db4dcb16201 238 SMART SM00967 2 72 8.9E-17 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Theos_0140 207c5eb1172428402d313db4dcb16201 238 Pfam PF00588 SpoU rRNA Methylase family 89 229 3.0E-35 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Theos_0140 207c5eb1172428402d313db4dcb16201 238 SUPERFAMILY SSF55315 1 68 3.03E-13 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like Theos_0140 207c5eb1172428402d313db4dcb16201 238 SUPERFAMILY SSF75217 60 233 2.42E-42 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Theos_0140 207c5eb1172428402d313db4dcb16201 238 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 2 71 1.4E-16 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Theos_0787 f44d2f7fc4f6424754cf090d6588c3a5 825 Pfam PF01103 Surface antigen 481 822 4.2E-21 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 Theos_0787 f44d2f7fc4f6424754cf090d6588c3a5 825 Gene3D G3DSA:3.10.20.310 303 378 1.0E-7 T 14-10-2018 Theos_0787 f44d2f7fc4f6424754cf090d6588c3a5 825 Gene3D G3DSA:3.10.20.310 168 241 2.1E-5 T 14-10-2018 Theos_0787 f44d2f7fc4f6424754cf090d6588c3a5 825 Pfam PF08479 POTRA domain, ShlB-type 170 240 1.3E-4 T 14-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type Theos_0787 f44d2f7fc4f6424754cf090d6588c3a5 825 Pfam PF07244 Surface antigen variable number repeat 308 364 5.4E-6 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Theos_0787 f44d2f7fc4f6424754cf090d6588c3a5 825 Pfam PF07244 Surface antigen variable number repeat 98 167 9.1E-7 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Theos_0787 f44d2f7fc4f6424754cf090d6588c3a5 825 Gene3D G3DSA:2.40.160.50 457 825 2.9E-20 T 14-10-2018 Theos_0787 f44d2f7fc4f6424754cf090d6588c3a5 825 Gene3D G3DSA:3.10.20.310 382 456 5.9E-9 T 14-10-2018 Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 Gene3D G3DSA:1.10.940.10 2 131 1.7E-24 T 14-10-2018 IPR035926 NusB-like superfamily Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 329 345 9.8E-15 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 377 394 9.8E-15 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 279 291 9.8E-15 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 219 229 9.8E-15 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 Pfam PF01029 NusB family 5 123 4.6E-15 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 Pfam PF01189 16S rRNA methyltransferase RsmB/F 208 393 1.6E-34 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 SUPERFAMILY SSF53335 128 394 3.8E-48 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 Gene3D G3DSA:3.40.50.150 149 394 7.0E-47 T 14-10-2018 Theos_1338 6bd9e0a38767b09deb4d411ed0958cc1 397 SUPERFAMILY SSF48013 6 139 6.05E-23 T 14-10-2018 IPR035926 NusB-like superfamily Theos_2413 51d5fd4ca0f45f87fb1a9a893aea0547 298 Gene3D G3DSA:1.10.10.2830 101 153 2.1E-7 T 14-10-2018 Theos_2413 51d5fd4ca0f45f87fb1a9a893aea0547 298 SMART SM00470 26 114 7.3E-36 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Theos_2413 51d5fd4ca0f45f87fb1a9a893aea0547 298 SUPERFAMILY SSF110849 28 139 1.41E-30 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Theos_2413 51d5fd4ca0f45f87fb1a9a893aea0547 298 Gene3D G3DSA:3.90.1530.30 39 100 4.2E-24 T 14-10-2018 Theos_2413 51d5fd4ca0f45f87fb1a9a893aea0547 298 SUPERFAMILY SSF109709 108 247 1.15E-14 T 14-10-2018 Theos_2413 51d5fd4ca0f45f87fb1a9a893aea0547 298 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 27 146 3.9E-34 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 Theos_2413 51d5fd4ca0f45f87fb1a9a893aea0547 298 Pfam PF02195 ParB-like nuclease domain 28 113 2.1E-26 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Theos_1616 ac13e0511540a8936b3daf2da39f84e6 428 SUPERFAMILY SSF55424 366 426 7.42E-10 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Theos_1616 ac13e0511540a8936b3daf2da39f84e6 428 Gene3D G3DSA:3.50.50.60 45 347 1.5E-85 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1616 ac13e0511540a8936b3daf2da39f84e6 428 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 45 163 1.3E-11 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Theos_1616 ac13e0511540a8936b3daf2da39f84e6 428 Gene3D G3DSA:3.50.50.60 157 287 1.5E-85 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1616 ac13e0511540a8936b3daf2da39f84e6 428 SUPERFAMILY SSF51905 171 287 3.28E-28 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1616 ac13e0511540a8936b3daf2da39f84e6 428 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 3 25 1.1E-6 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Theos_1616 ac13e0511540a8936b3daf2da39f84e6 428 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 367 425 3.3E-10 T 14-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 Theos_1616 ac13e0511540a8936b3daf2da39f84e6 428 SUPERFAMILY SSF51905 44 164 1.6E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1616 ac13e0511540a8936b3daf2da39f84e6 428 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 24 8.1E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Theos_1913 29f304e7a4feff06d07978893e9dff6b 395 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 156 392 1.9E-68 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 Theos_1913 29f304e7a4feff06d07978893e9dff6b 395 Gene3D G3DSA:1.10.3720.10 167 394 2.9E-33 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1913 29f304e7a4feff06d07978893e9dff6b 395 SUPERFAMILY SSF161098 171 382 5.63E-37 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1913 29f304e7a4feff06d07978893e9dff6b 395 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 196 385 6.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1026 32612cc27443a68e23db23defedd5a77 843 SUPERFAMILY SSF55073 446 595 6.36E-45 T 14-10-2018 IPR029787 Nucleotide cyclase Theos_1026 32612cc27443a68e23db23defedd5a77 843 SMART SM00267 430 593 1.5E-58 T 14-10-2018 IPR000160 GGDEF domain Theos_1026 32612cc27443a68e23db23defedd5a77 843 Gene3D G3DSA:3.30.450.40 269 434 2.9E-15 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1026 32612cc27443a68e23db23defedd5a77 843 Pfam PF00990 Diguanylate cyclase, GGDEF domain 441 589 2.2E-38 T 14-10-2018 IPR000160 GGDEF domain Theos_1026 32612cc27443a68e23db23defedd5a77 843 Pfam PF00563 EAL domain 609 839 3.0E-53 T 14-10-2018 IPR001633 EAL domain Theos_1026 32612cc27443a68e23db23defedd5a77 843 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 438 591 6.8E-35 T 14-10-2018 IPR000160 GGDEF domain Theos_1026 32612cc27443a68e23db23defedd5a77 843 Gene3D G3DSA:3.20.20.450 605 843 8.1E-67 T 14-10-2018 IPR035919 EAL domain superfamily Theos_1026 32612cc27443a68e23db23defedd5a77 843 SUPERFAMILY SSF55781 287 441 1.31E-15 T 14-10-2018 Theos_1026 32612cc27443a68e23db23defedd5a77 843 SUPERFAMILY SSF141868 617 840 9.02E-59 T 14-10-2018 IPR035919 EAL domain superfamily Theos_1026 32612cc27443a68e23db23defedd5a77 843 Pfam PF13185 GAF domain 286 428 2.3E-8 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1026 32612cc27443a68e23db23defedd5a77 843 Gene3D G3DSA:3.30.70.270 439 604 1.0E-49 T 14-10-2018 Theos_1026 32612cc27443a68e23db23defedd5a77 843 SMART SM00052 599 841 2.1E-57 T 14-10-2018 IPR001633 EAL domain Theos_1026 32612cc27443a68e23db23defedd5a77 843 Pfam PF01590 GAF domain 26 164 4.0E-11 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1026 32612cc27443a68e23db23defedd5a77 843 Gene3D G3DSA:3.30.450.40 21 176 1.4E-21 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1026 32612cc27443a68e23db23defedd5a77 843 SMART SM00065 274 438 0.0035 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1026 32612cc27443a68e23db23defedd5a77 843 SMART SM00065 19 174 9.4E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1026 32612cc27443a68e23db23defedd5a77 843 SUPERFAMILY SSF55781 24 165 1.18E-19 T 14-10-2018 Theos_0350 399f9e539749624617d88445cb18ea4b 655 SMART SM00220 97 364 6.1E-72 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Theos_0350 399f9e539749624617d88445cb18ea4b 655 SUPERFAMILY SSF63825 381 637 5.23E-20 T 14-10-2018 Theos_0350 399f9e539749624617d88445cb18ea4b 655 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 215 227 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Theos_0350 399f9e539749624617d88445cb18ea4b 655 Pfam PF00069 Protein kinase domain 97 356 2.6E-54 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Theos_0350 399f9e539749624617d88445cb18ea4b 655 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 103 126 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 Theos_0350 399f9e539749624617d88445cb18ea4b 655 Gene3D G3DSA:3.30.200.20 88 176 2.9E-29 T 14-10-2018 Theos_0350 399f9e539749624617d88445cb18ea4b 655 SUPERFAMILY SSF56112 91 357 3.64E-80 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Theos_0350 399f9e539749624617d88445cb18ea4b 655 Gene3D G3DSA:1.10.510.10 177 371 2.4E-48 T 14-10-2018 Theos_0350 399f9e539749624617d88445cb18ea4b 655 Gene3D G3DSA:2.120.10.30 396 630 2.8E-24 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 Pfam PF07724 AAA domain (Cdc48 subfamily) 100 290 1.3E-47 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 SMART SM01086 297 388 8.6E-29 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 297 370 1.5E-14 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 Gene3D G3DSA:1.10.8.60 296 396 1.3E-33 T 14-10-2018 Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 4 374 3.1E-165 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 SUPERFAMILY SSF52540 58 381 4.76E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 Pfam PF06689 ClpX C4-type zinc finger 7 45 1.3E-10 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 Gene3D G3DSA:3.30.50.30 2 46 3.6E-8 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 SUPERFAMILY SSF57716 6 43 1.28E-5 T 14-10-2018 Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 SMART SM00994 5 46 4.2E-11 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 Gene3D G3DSA:3.40.50.300 53 295 3.0E-99 T 14-10-2018 Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 SMART SM00382 99 313 3.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1346 dc14f8204310b4cdf1bf72a9dda18bf4 398 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 1 394 48.14 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Theos_1281 b1bcb6be0b7b38a69005dd27963266fc 290 PIRSF PIRSF000105 1 290 1.3E-92 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 Theos_1281 b1bcb6be0b7b38a69005dd27963266fc 290 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 1.1E-64 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Theos_1281 b1bcb6be0b7b38a69005dd27963266fc 290 Gene3D G3DSA:1.10.1040.10 189 289 2.6E-37 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Theos_1281 b1bcb6be0b7b38a69005dd27963266fc 290 SUPERFAMILY SSF48179 185 287 4.0E-35 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Theos_1281 b1bcb6be0b7b38a69005dd27963266fc 290 SUPERFAMILY SSF51735 1 185 8.3E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1281 b1bcb6be0b7b38a69005dd27963266fc 290 Gene3D G3DSA:3.40.50.720 1 188 4.6E-68 T 14-10-2018 Theos_1281 b1bcb6be0b7b38a69005dd27963266fc 290 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 2.2E-36 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 SUPERFAMILY SSF57716 213 262 2.65E-17 T 14-10-2018 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 263 39.743 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 SUPERFAMILY SSF81624 2 124 2.88E-31 T 14-10-2018 IPR035937 MutM-like, N-terminal Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 ProSitePatterns PS01242 Zinc finger FPG-type signature. 238 262 - T 14-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 Gene3D G3DSA:3.20.190.10 2 121 3.9E-38 T 14-10-2018 IPR035937 MutM-like, N-terminal Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 105 4.8E-25 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 Pfam PF06827 Zinc finger found in FPG and IleRS 235 262 9.7E-13 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 SMART SM01232 122 213 7.3E-39 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 Gene3D G3DSA:1.10.8.50 122 258 9.7E-48 T 14-10-2018 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 SMART SM00898 2 106 1.0E-31 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 210 1.2E-23 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 262 1.7E-82 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 Theos_2026 8cd490ea5f3766197fcadf37e51a7b62 263 SUPERFAMILY SSF46946 121 210 5.45E-27 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Theos_1370 5f607bdf2dae3c64bbe65ced94e12e03 452 Pfam PF01593 Flavin containing amine oxidoreductase 12 440 2.8E-60 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 Theos_1370 5f607bdf2dae3c64bbe65ced94e12e03 452 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 445 2.5E-77 T 14-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Theos_1370 5f607bdf2dae3c64bbe65ced94e12e03 452 Gene3D G3DSA:3.50.50.60 4 436 5.7E-122 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1370 5f607bdf2dae3c64bbe65ced94e12e03 452 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.1E-5 T 14-10-2018 Theos_1370 5f607bdf2dae3c64bbe65ced94e12e03 452 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 2.1E-5 T 14-10-2018 Theos_1370 5f607bdf2dae3c64bbe65ced94e12e03 452 SUPERFAMILY SSF51905 4 440 4.4E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1370 5f607bdf2dae3c64bbe65ced94e12e03 452 SUPERFAMILY SSF54373 292 392 7.65E-20 T 14-10-2018 Theos_1370 5f607bdf2dae3c64bbe65ced94e12e03 452 Gene3D G3DSA:3.90.660.20 39 393 5.7E-122 T 14-10-2018 Theos_1370 5f607bdf2dae3c64bbe65ced94e12e03 452 Gene3D G3DSA:1.10.3110.10 96 202 5.7E-122 T 14-10-2018 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 PRINTS PR00988 Uridine kinase signature 5 22 1.2E-33 T 14-10-2018 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 PRINTS PR00988 Uridine kinase signature 149 160 1.2E-33 T 14-10-2018 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 PRINTS PR00988 Uridine kinase signature 34 45 1.2E-33 T 14-10-2018 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 PRINTS PR00988 Uridine kinase signature 171 184 1.2E-33 T 14-10-2018 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 PRINTS PR00988 Uridine kinase signature 79 94 1.2E-33 T 14-10-2018 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 PRINTS PR00988 Uridine kinase signature 135 145 1.2E-33 T 14-10-2018 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 Hamap MF_00551 Uridine kinase [udk]. 2 205 37.382 T 14-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 Gene3D G3DSA:3.40.50.300 1 208 3.6E-71 T 14-10-2018 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 SUPERFAMILY SSF52540 3 197 2.42E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 190 3.7E-38 T 14-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 Theos_1395 809595f8bc0c1aa54a2dba004919b2e7 209 TIGRFAM TIGR00235 udk: uridine kinase 5 199 1.9E-73 T 14-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 Theos_0170 61b63786154115f819b0e945c8ed8f2e 938 Pfam PF00395 S-layer homology domain 25 67 1.8E-12 T 14-10-2018 IPR001119 S-layer homology domain Theos_0170 61b63786154115f819b0e945c8ed8f2e 938 Gene3D G3DSA:1.20.5.340 152 313 3.8E-7 T 14-10-2018 Theos_0197 aa2fc020e19bccbb6d777172cdba7b4a 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 43 51 4.9E-15 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Theos_0197 aa2fc020e19bccbb6d777172cdba7b4a 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 86 101 4.9E-15 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Theos_0197 aa2fc020e19bccbb6d777172cdba7b4a 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 4.9E-15 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Theos_0197 aa2fc020e19bccbb6d777172cdba7b4a 150 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 150 13.501 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Theos_0197 aa2fc020e19bccbb6d777172cdba7b4a 150 Pfam PF01252 Signal peptidase (SPase) II 7 141 4.4E-29 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Theos_0197 aa2fc020e19bccbb6d777172cdba7b4a 150 TIGRFAM TIGR00077 lspA: signal peptidase II 8 142 1.4E-26 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Theos_0197 aa2fc020e19bccbb6d777172cdba7b4a 150 ProSitePatterns PS00855 Signal peptidases II signature. 89 101 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Theos_1911 707e8eb2508754f49a573ad5c43bb50d 324 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 17 281 9.8E-91 T 14-10-2018 IPR011862 Phosphate binding protein GO:0042301 Theos_1911 707e8eb2508754f49a573ad5c43bb50d 324 Gene3D G3DSA:3.40.190.10 23 280 6.5E-97 T 14-10-2018 Theos_1911 707e8eb2508754f49a573ad5c43bb50d 324 Gene3D G3DSA:3.40.190.10 102 243 6.5E-97 T 14-10-2018 Theos_1911 707e8eb2508754f49a573ad5c43bb50d 324 SUPERFAMILY SSF53850 22 295 7.38E-75 T 14-10-2018 Theos_1911 707e8eb2508754f49a573ad5c43bb50d 324 Pfam PF12727 PBP superfamily domain 39 265 2.3E-35 T 14-10-2018 IPR024370 PBP domain Theos_0796 de457fcdf780ee180f7bfca7745254dc 343 SUPERFAMILY SSF50129 1 174 2.43E-55 T 14-10-2018 IPR011032 GroES-like superfamily Theos_0796 de457fcdf780ee180f7bfca7745254dc 343 SUPERFAMILY SSF51735 142 305 5.79E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0796 de457fcdf780ee180f7bfca7745254dc 343 SMART SM00829 9 339 5.7E-7 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Theos_0796 de457fcdf780ee180f7bfca7745254dc 343 Gene3D G3DSA:3.90.180.10 19 333 3.5E-131 T 14-10-2018 Theos_0796 de457fcdf780ee180f7bfca7745254dc 343 Pfam PF00107 Zinc-binding dehydrogenase 175 295 8.0E-16 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Theos_0796 de457fcdf780ee180f7bfca7745254dc 343 Gene3D G3DSA:3.40.50.720 153 286 3.5E-131 T 14-10-2018 Theos_0796 de457fcdf780ee180f7bfca7745254dc 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Theos_0796 de457fcdf780ee180f7bfca7745254dc 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 132 7.4E-35 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Theos_0772 4dee1ac402754cdfb5ac717371018abe 233 Gene3D G3DSA:3.10.290.10 1 48 3.1E-10 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Theos_0772 4dee1ac402754cdfb5ac717371018abe 233 Pfam PF01728 FtsJ-like methyltransferase 54 230 8.0E-19 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 Theos_0772 4dee1ac402754cdfb5ac717371018abe 233 SMART SM00363 1 61 1.4E-12 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0772 4dee1ac402754cdfb5ac717371018abe 233 SUPERFAMILY SSF53335 50 231 9.64E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0772 4dee1ac402754cdfb5ac717371018abe 233 PIRSF PIRSF005578 1 233 5.3E-85 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 Theos_0772 4dee1ac402754cdfb5ac717371018abe 233 Gene3D G3DSA:3.40.50.150 49 233 2.4E-73 T 14-10-2018 Theos_0772 4dee1ac402754cdfb5ac717371018abe 233 SUPERFAMILY SSF55174 1 49 6.77E-11 T 14-10-2018 Theos_0772 4dee1ac402754cdfb5ac717371018abe 233 Pfam PF01479 S4 domain 1 45 1.3E-14 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0772 4dee1ac402754cdfb5ac717371018abe 233 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 2 225 7.3E-62 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 Theos_1485 ad3bc1833c5999ba9ebb5b66e24176f9 151 SUPERFAMILY SSF48013 2 139 1.83E-31 T 14-10-2018 IPR035926 NusB-like superfamily Theos_1485 ad3bc1833c5999ba9ebb5b66e24176f9 151 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 140 17.45 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 Theos_1485 ad3bc1833c5999ba9ebb5b66e24176f9 151 Pfam PF01029 NusB family 3 137 4.5E-33 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Theos_1485 ad3bc1833c5999ba9ebb5b66e24176f9 151 Gene3D G3DSA:1.10.940.10 1 150 1.1E-37 T 14-10-2018 IPR035926 NusB-like superfamily Theos_1485 ad3bc1833c5999ba9ebb5b66e24176f9 151 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 138 5.6E-34 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 Theos_1559 d424703e0c118cce15840b1a4f32277b 446 Gene3D G3DSA:1.10.3080.10 16 406 1.6E-38 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 Theos_1559 d424703e0c118cce15840b1a4f32277b 446 Pfam PF00654 Voltage gated chloride channel 115 402 1.5E-34 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Theos_1559 d424703e0c118cce15840b1a4f32277b 446 SUPERFAMILY SSF81340 13 403 8.5E-46 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 Theos_1769 811b5898cf790aaf143b6eb2dbe27cdd 400 Pfam PF13458 Periplasmic binding protein 26 379 3.8E-56 T 14-10-2018 IPR028081 Leucine-binding protein domain Theos_1769 811b5898cf790aaf143b6eb2dbe27cdd 400 SUPERFAMILY SSF53822 25 384 9.42E-54 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_1769 811b5898cf790aaf143b6eb2dbe27cdd 400 Gene3D G3DSA:3.40.50.2300 29 347 1.6E-119 T 14-10-2018 Theos_1769 811b5898cf790aaf143b6eb2dbe27cdd 400 Gene3D G3DSA:3.40.50.2300 138 276 1.6E-119 T 14-10-2018 Theos_1713 a49520455cb939694352d906eaae626f 596 Pfam PF05746 DALR anticodon binding domain 477 596 9.6E-29 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Theos_1713 a49520455cb939694352d906eaae626f 596 Gene3D G3DSA:3.30.1360.70 5 103 2.0E-19 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 Theos_1713 a49520455cb939694352d906eaae626f 596 Pfam PF00750 tRNA synthetases class I (R) 107 169 5.4E-12 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 Theos_1713 a49520455cb939694352d906eaae626f 596 Pfam PF00750 tRNA synthetases class I (R) 349 451 1.3E-8 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 Theos_1713 a49520455cb939694352d906eaae626f 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 108 123 2.5E-19 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Theos_1713 a49520455cb939694352d906eaae626f 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 123 139 2.5E-19 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Theos_1713 a49520455cb939694352d906eaae626f 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 147 160 2.5E-19 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Theos_1713 a49520455cb939694352d906eaae626f 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 295 316 2.5E-19 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Theos_1713 a49520455cb939694352d906eaae626f 596 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 86 3.3E-13 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_1713 a49520455cb939694352d906eaae626f 596 Gene3D G3DSA:3.40.50.620 108 480 1.7E-108 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1713 a49520455cb939694352d906eaae626f 596 SMART SM01016 4 86 1.4E-18 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_1713 a49520455cb939694352d906eaae626f 596 SMART SM00836 477 596 5.5E-27 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Theos_1713 a49520455cb939694352d906eaae626f 596 SUPERFAMILY SSF52374 102 469 1.71E-71 T 14-10-2018 Theos_1713 a49520455cb939694352d906eaae626f 596 Gene3D G3DSA:1.10.730.10 481 596 9.0E-35 T 14-10-2018 Theos_1713 a49520455cb939694352d906eaae626f 596 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 118 127 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1713 a49520455cb939694352d906eaae626f 596 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 596 22.423 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Theos_1713 a49520455cb939694352d906eaae626f 596 SUPERFAMILY SSF55190 7 95 1.96E-17 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 Theos_1713 a49520455cb939694352d906eaae626f 596 SUPERFAMILY SSF47323 471 596 7.19E-30 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 ProSitePatterns PS00674 AAA-protein family signature. 303 321 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 SMART SM00382 196 335 9.7E-25 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 Gene3D G3DSA:1.10.8.60 334 411 5.1E-27 T 14-10-2018 Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 SUPERFAMILY SSF52540 156 404 6.63E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 610 35.239 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 113 602 9.5E-215 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 Pfam PF01434 Peptidase family M41 395 601 5.8E-68 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 200 332 7.0E-45 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 Gene3D G3DSA:3.40.50.300 150 332 2.8E-69 T 14-10-2018 Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 SUPERFAMILY SSF140990 415 607 8.5E-63 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Theos_0659 2067ceaea635b85fd2fa98bc9e1fb020 614 Gene3D G3DSA:1.20.58.760 415 613 7.7E-70 T 14-10-2018 Theos_2069 c372444499607f9e86e1ac1a5532475b 284 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 252 1.2E-47 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Theos_2069 c372444499607f9e86e1ac1a5532475b 284 SUPERFAMILY SSF54211 4 146 3.64E-36 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_2069 c372444499607f9e86e1ac1a5532475b 284 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 1 261 29.761 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Theos_2069 c372444499607f9e86e1ac1a5532475b 284 Gene3D G3DSA:3.30.70.890 149 266 3.2E-32 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Theos_2069 c372444499607f9e86e1ac1a5532475b 284 SUPERFAMILY SSF55060 149 257 4.68E-23 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Theos_2069 c372444499607f9e86e1ac1a5532475b 284 Pfam PF08544 GHMP kinases C terminal 196 257 5.3E-10 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain Theos_2069 c372444499607f9e86e1ac1a5532475b 284 Pfam PF00288 GHMP kinases N terminal domain 78 133 3.6E-7 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Theos_2069 c372444499607f9e86e1ac1a5532475b 284 PIRSF PIRSF010376 1 267 4.0E-72 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Theos_2069 c372444499607f9e86e1ac1a5532475b 284 Gene3D G3DSA:3.30.230.10 1 148 3.2E-47 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Gene3D G3DSA:1.10.8.60 335 431 2.1E-25 T 14-10-2018 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 SUPERFAMILY SSF52540 154 399 1.17E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 331 8.3E-14 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Gene3D G3DSA:1.10.8.60 642 732 6.3E-12 T 14-10-2018 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 481 499 6.4E-36 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 555 573 6.4E-36 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 526 544 6.4E-36 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 588 602 6.4E-36 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 67 2.7E-13 T 14-10-2018 IPR004176 Clp, N-terminal Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 91 141 1.6E-12 T 14-10-2018 IPR004176 Clp, N-terminal Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Gene3D G3DSA:3.40.50.300 432 640 3.7E-75 T 14-10-2018 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Gene3D G3DSA:1.10.1780.10 1 146 4.3E-42 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 SUPERFAMILY SSF52540 435 704 1.23E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 287 299 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Pfam PF07724 AAA domain (Cdc48 subfamily) 479 636 5.5E-45 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Gene3D G3DSA:3.40.50.300 147 334 2.4E-70 T 14-10-2018 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 SUPERFAMILY SSF81923 3 146 4.19E-23 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 SMART SM01086 642 727 1.3E-17 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 481 494 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 SMART SM00382 477 643 1.4E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 SMART SM00382 193 336 1.7E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0769 9a854a7641ac0a01aabb1fa44a7bed78 738 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 642 712 1.3E-12 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Theos_1339 ce78ef4c350726f03b06b42f0cc1a552 90 Gene3D G3DSA:3.30.110.20 1 90 1.8E-39 T 14-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 Theos_1339 ce78ef4c350726f03b06b42f0cc1a552 90 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 4 84 5.0E-39 T 14-10-2018 IPR007347 Sporulation stage V, protein S Theos_1339 ce78ef4c350726f03b06b42f0cc1a552 90 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 83 2.3E-37 T 14-10-2018 IPR007347 Sporulation stage V, protein S Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 Gene3D G3DSA:3.90.230.10 1 252 1.1E-98 T 14-10-2018 Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 166 184 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 247 2.1E-91 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 SUPERFAMILY SSF55920 4 250 1.26E-83 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 Hamap MF_01974 Methionine aminopeptidase [map]. 3 249 39.181 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 Pfam PF00557 Metallopeptidase family M24 12 240 2.8E-53 T 14-10-2018 IPR000994 Peptidase M24 Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 68 81 1.6E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 1.6E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 160 172 1.6E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_0299 e63db8faffad2cd2d7173be4631f22bc 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 1.6E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_0250 5ad3058debfd5835c98ef9b691514162 132 Gene3D G3DSA:3.90.79.10 1 123 2.0E-12 T 14-10-2018 Theos_0250 5ad3058debfd5835c98ef9b691514162 132 SUPERFAMILY SSF55811 2 118 1.35E-14 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Theos_0250 5ad3058debfd5835c98ef9b691514162 132 Pfam PF00293 NUDIX domain 3 114 7.9E-7 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Theos_1260 5fcda5d587ec25f717751ea35a4e35aa 358 SMART SM00382 33 216 7.3E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1260 5fcda5d587ec25f717751ea35a4e35aa 358 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1260 5fcda5d587ec25f717751ea35a4e35aa 358 Gene3D G3DSA:3.40.50.300 4 243 4.1E-76 T 14-10-2018 Theos_1260 5fcda5d587ec25f717751ea35a4e35aa 358 SUPERFAMILY SSF50331 243 356 4.25E-12 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Theos_1260 5fcda5d587ec25f717751ea35a4e35aa 358 SUPERFAMILY SSF52540 9 246 5.58E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1260 5fcda5d587ec25f717751ea35a4e35aa 358 Pfam PF00005 ABC transporter 24 166 5.5E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1260 5fcda5d587ec25f717751ea35a4e35aa 358 Pfam PF08402 TOBE domain 273 355 4.5E-7 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 TIGRFAM TIGR00484 EF-G: translation elongation factor G 6 689 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Pfam PF03144 Elongation factor Tu domain 2 323 389 1.1E-15 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Hamap MF_00054_B Elongation factor G [fusA]. 8 691 114.32 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 SUPERFAMILY SSF54980 402 480 7.91E-26 T 14-10-2018 IPR035647 EF-G domain III/V-like Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Gene3D G3DSA:3.30.230.10 484 687 2.4E-99 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_0274 859ef00f22a686345435bfca740b4e1c 691 SUPERFAMILY SSF54211 479 599 1.31E-49 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_0274 859ef00f22a686345435bfca740b4e1c 691 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Gene3D G3DSA:3.40.50.300 1 286 3.6E-112 T 14-10-2018 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 181 8.9E-33 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 SUPERFAMILY SSF50447 265 395 1.64E-36 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_0274 859ef00f22a686345435bfca740b4e1c 691 PRINTS PR00315 GTP-binding elongation factor signature 132 141 4.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 PRINTS PR00315 GTP-binding elongation factor signature 96 107 4.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 PRINTS PR00315 GTP-binding elongation factor signature 60 68 4.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 PRINTS PR00315 GTP-binding elongation factor signature 80 90 4.5E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Pfam PF00679 Elongation factor G C-terminus 600 686 3.0E-34 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Theos_0274 859ef00f22a686345435bfca740b4e1c 691 SMART SM00838 600 687 1.3E-60 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Gene3D G3DSA:3.30.70.870 405 483 7.2E-34 T 14-10-2018 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Pfam PF03764 Elongation factor G, domain IV 479 597 3.0E-51 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Pfam PF00009 Elongation factor Tu GTP binding domain 10 282 1.6E-68 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Gene3D G3DSA:3.30.70.240 604 674 2.4E-99 T 14-10-2018 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 SUPERFAMILY SSF54980 603 689 4.41E-34 T 14-10-2018 IPR035647 EF-G domain III/V-like Theos_0274 859ef00f22a686345435bfca740b4e1c 691 SMART SM00889 480 598 2.6E-78 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 SUPERFAMILY SSF52540 7 282 5.81E-111 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Pfam PF14492 Elongation Factor G, domain II 404 478 8.6E-36 T 14-10-2018 Theos_0274 859ef00f22a686345435bfca740b4e1c 691 Gene3D G3DSA:2.40.30.10 288 400 2.4E-43 T 14-10-2018 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 5 414 22.369 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 Gene3D G3DSA:3.40.50.10490 204 409 2.3E-127 T 14-10-2018 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 Gene3D G3DSA:3.40.50.10490 66 203 2.3E-127 T 14-10-2018 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 Pfam PF00342 Phosphoglucose isomerase 66 411 1.8E-35 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 PRINTS PR00662 Glucose-6-phosphate isomerase signature 357 375 9.1E-22 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 PRINTS PR00662 Glucose-6-phosphate isomerase signature 178 196 9.1E-22 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 PRINTS PR00662 Glucose-6-phosphate isomerase signature 250 271 9.1E-22 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 PRINTS PR00662 Glucose-6-phosphate isomerase signature 389 402 9.1E-22 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 PRINTS PR00662 Glucose-6-phosphate isomerase signature 69 88 9.1E-22 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 SUPERFAMILY SSF53697 26 414 2.89E-96 T 14-10-2018 Theos_0032 717dfce4c87ad3a79faf97c781096636 414 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 389 406 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 Gene3D G3DSA:3.30.230.10 596 777 2.7E-78 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 Hamap MF_01973 Lon protease [lon]. 8 775 69.853 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 679 687 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 TIGRFAM TIGR00763 lon: endopeptidase La 9 773 2.1E-280 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 Gene3D G3DSA:1.20.58.1480 118 244 5.3E-36 T 14-10-2018 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 SMART SM00464 7 201 1.9E-55 T 14-10-2018 IPR003111 Lon, substrate-binding domain Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 355 492 3.2E-20 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 729 747 2.9E-51 T 14-10-2018 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 676 695 2.9E-51 T 14-10-2018 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 598 614 2.9E-51 T 14-10-2018 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 359 378 2.9E-51 T 14-10-2018 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 706 725 2.9E-51 T 14-10-2018 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 SUPERFAMILY SSF54211 598 773 1.4E-56 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 SMART SM00382 351 496 3.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 PIRSF PIRSF001174 1 778 1.7E-301 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 SUPERFAMILY SSF52540 312 593 2.31E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 Gene3D G3DSA:1.10.8.60 495 587 6.0E-23 T 14-10-2018 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 199 3.8E-35 T 14-10-2018 IPR003111 Lon, substrate-binding domain Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 Gene3D G3DSA:3.40.50.300 314 494 3.2E-64 T 14-10-2018 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 SUPERFAMILY SSF88697 7 199 6.46E-38 T 14-10-2018 IPR015947 PUA-like superfamily Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 Gene3D G3DSA:2.30.130.40 1 113 1.7E-29 T 14-10-2018 Theos_0547 d5fbcd6bb91e60b2bc2c82b89999d547 793 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 573 774 1.0E-92 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Gene3D G3DSA:3.40.50.800 550 658 2.1E-32 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 228 6.5E-12 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 377 400 7.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 344 372 7.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 525 538 7.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 482 510 7.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 552 564 7.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Pfam PF03129 Anticodon binding domain 559 644 2.0E-22 T 14-10-2018 IPR004154 Anticodon-binding Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Gene3D G3DSA:3.30.54.20 136 195 6.0E-55 T 14-10-2018 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 336 546 1.1E-41 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Gene3D G3DSA:3.10.20.30 1 63 9.3E-19 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 SMART SM00863 174 228 1.8E-21 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 SUPERFAMILY SSF55186 62 250 7.33E-53 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 SUPERFAMILY SSF81271 2 60 3.92E-14 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Gene3D G3DSA:3.30.930.10 232 549 3.6E-120 T 14-10-2018 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 65 652 35.583 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 SUPERFAMILY SSF52954 548 651 1.22E-29 T 14-10-2018 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Pfam PF02824 TGS domain 1 60 8.5E-17 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 71 646 1.8E-210 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 SUPERFAMILY SSF55681 252 544 5.94E-92 T 14-10-2018 Theos_2002 41956f090f30207f95a3bc7ea244a8e4 659 Gene3D G3DSA:3.30.980.10 68 231 6.0E-55 T 14-10-2018 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 SUPERFAMILY SSF158472 145 193 1.44E-7 T 14-10-2018 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 SMART SM00387 292 398 7.8E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 Gene3D G3DSA:1.10.287.130 147 260 3.4E-25 T 14-10-2018 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 SUPERFAMILY SSF47384 180 256 1.88E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 199 258 2.2E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 SMART SM00388 197 260 8.3E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 SUPERFAMILY SSF55874 263 396 7.73E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 Pfam PF00672 HAMP domain 144 193 5.7E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 397 8.5E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 356 1.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 342 1.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 376 1.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 SMART SM00304 143 196 2.1E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Theos_0063 d421d8533db091914ba03bfe73dfcbad 409 Gene3D G3DSA:3.30.565.10 261 401 3.2E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1671 02b5d3d94836ca5a3dc31dce77e945fe 540 TIGRFAM TIGR00337 PyrG: CTP synthase 1 531 6.4E-234 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Theos_1671 02b5d3d94836ca5a3dc31dce77e945fe 540 Pfam PF06418 CTP synthase N-terminus 2 266 3.9E-123 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Theos_1671 02b5d3d94836ca5a3dc31dce77e945fe 540 Gene3D G3DSA:3.40.50.880 286 538 2.2E-106 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1671 02b5d3d94836ca5a3dc31dce77e945fe 540 Hamap MF_01227 CTP synthase [pyrG]. 1 536 51.95 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Theos_1671 02b5d3d94836ca5a3dc31dce77e945fe 540 SUPERFAMILY SSF52317 289 535 4.43E-78 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1671 02b5d3d94836ca5a3dc31dce77e945fe 540 SUPERFAMILY SSF52540 1 268 1.57E-117 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1671 02b5d3d94836ca5a3dc31dce77e945fe 540 Gene3D G3DSA:3.40.50.300 1 285 2.9E-134 T 14-10-2018 Theos_1671 02b5d3d94836ca5a3dc31dce77e945fe 540 Pfam PF00117 Glutamine amidotransferase class-I 301 531 3.1E-49 T 14-10-2018 IPR017926 Glutamine amidotransferase Theos_0006 8582668fc7be47d1e44060b1c7c561fa 255 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 9 223 4.0E-62 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Theos_0006 8582668fc7be47d1e44060b1c7c561fa 255 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 11 216 3.7E-23 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0006 8582668fc7be47d1e44060b1c7c561fa 255 SUPERFAMILY SSF51366 10 250 2.83E-55 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Theos_0006 8582668fc7be47d1e44060b1c7c561fa 255 Gene3D G3DSA:3.20.20.70 11 253 2.6E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0006 8582668fc7be47d1e44060b1c7c561fa 255 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 81 94 - T 14-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_0006 8582668fc7be47d1e44060b1c7c561fa 255 SMART SM00934 11 243 1.4E-15 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Theos_1391 9f2329651b47a8b52e93265b302c38b6 352 PIRSF PIRSF000524 1 350 1.3E-81 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 Theos_1391 9f2329651b47a8b52e93265b302c38b6 352 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 176 196 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Theos_1391 9f2329651b47a8b52e93265b302c38b6 352 Gene3D G3DSA:3.90.1150.10 4 331 6.2E-116 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_1391 9f2329651b47a8b52e93265b302c38b6 352 Gene3D G3DSA:3.40.640.10 13 249 6.2E-116 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_1391 9f2329651b47a8b52e93265b302c38b6 352 SUPERFAMILY SSF53383 3 346 3.27E-78 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_1391 9f2329651b47a8b52e93265b302c38b6 352 Pfam PF00266 Aminotransferase class-V 21 324 5.4E-23 T 14-10-2018 IPR000192 Aminotransferase class V domain Theos_0865 3875d9f7341cdb3aee73290c2c6f882f 247 Pfam PF01925 Sulfite exporter TauE/SafE 5 241 2.1E-47 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Theos_1662 9715c487b41c00f830ccc49c8efb7b1e 144 Gene3D G3DSA:3.60.90.10 2 130 1.7E-36 T 14-10-2018 Theos_1662 9715c487b41c00f830ccc49c8efb7b1e 144 SUPERFAMILY SSF56276 6 119 2.59E-27 T 14-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 Theos_1662 9715c487b41c00f830ccc49c8efb7b1e 144 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 118 4.7E-24 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 Theos_1662 9715c487b41c00f830ccc49c8efb7b1e 144 Pfam PF02675 S-adenosylmethionine decarboxylase 9 118 6.9E-29 T 14-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 Theos_0575 efc81f93d6f136dfa9c2e262621163f0 359 SUPERFAMILY SSF48179 175 280 7.03E-25 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Theos_0575 efc81f93d6f136dfa9c2e262621163f0 359 Pfam PF02153 Prephenate dehydrogenase 20 260 5.9E-50 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 Theos_0575 efc81f93d6f136dfa9c2e262621163f0 359 Gene3D G3DSA:3.40.50.720 5 177 2.6E-45 T 14-10-2018 Theos_0575 efc81f93d6f136dfa9c2e262621163f0 359 Pfam PF01842 ACT domain 294 329 3.1E-8 T 14-10-2018 IPR002912 ACT domain Theos_0575 efc81f93d6f136dfa9c2e262621163f0 359 SUPERFAMILY SSF55021 289 337 1.5E-9 T 14-10-2018 Theos_0575 efc81f93d6f136dfa9c2e262621163f0 359 Gene3D G3DSA:1.10.3660.10 178 281 3.9E-26 T 14-10-2018 Theos_0575 efc81f93d6f136dfa9c2e262621163f0 359 Gene3D G3DSA:3.30.70.260 292 356 5.9E-10 T 14-10-2018 Theos_0575 efc81f93d6f136dfa9c2e262621163f0 359 SUPERFAMILY SSF51735 7 168 6.18E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0602 958dd4ebec380783b1f871f2a78106a3 868 Pfam PF09397 Ftsk gamma domain 799 859 1.6E-24 T 14-10-2018 IPR018541 FtsK gamma domain Theos_0602 958dd4ebec380783b1f871f2a78106a3 868 Pfam PF01580 FtsK/SpoIIIE family 510 642 5.4E-40 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Theos_0602 958dd4ebec380783b1f871f2a78106a3 868 Gene3D G3DSA:1.10.10.10 792 857 3.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0602 958dd4ebec380783b1f871f2a78106a3 868 Gene3D G3DSA:3.40.50.300 501 777 1.8E-96 T 14-10-2018 Theos_0602 958dd4ebec380783b1f871f2a78106a3 868 SMART SM00843 796 861 2.0E-31 T 14-10-2018 IPR018541 FtsK gamma domain Theos_0602 958dd4ebec380783b1f871f2a78106a3 868 SUPERFAMILY SSF46785 797 862 2.01E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0602 958dd4ebec380783b1f871f2a78106a3 868 SUPERFAMILY SSF52540 478 760 1.27E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0602 958dd4ebec380783b1f871f2a78106a3 868 Gene3D G3DSA:3.30.980.40 395 500 7.0E-34 T 14-10-2018 Theos_0602 958dd4ebec380783b1f871f2a78106a3 868 SMART SM00382 539 707 0.0037 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 Gene3D G3DSA:1.10.8.280 287 405 8.3E-246 T 14-10-2018 Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 Gene3D G3DSA:1.20.1580.10 695 832 2.3E-144 T 14-10-2018 Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 ProSitePatterns PS00211 ABC transporters family signature. 832 846 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 Gene3D G3DSA:1.20.1580.10 90 496 8.3E-246 T 14-10-2018 Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 SUPERFAMILY SSF52540 620 912 4.18E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 941 23.031 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 SMART SM00382 23 231 5.7 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 SMART SM00382 635 908 1.6E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 SUPERFAMILY SSF52540 6 573 1.83E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 Gene3D G3DSA:3.40.50.300 617 937 2.3E-144 T 14-10-2018 Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 927 0.0 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 Gene3D G3DSA:3.40.50.300 5 598 8.3E-246 T 14-10-2018 Theos_1640 a3ac82d8885401fb252b2f8cbf77f4fa 952 Gene3D G3DSA:3.30.190.20 130 244 8.3E-246 T 14-10-2018 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 Pfam PF00072 Response regulator receiver domain 4 113 2.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 SUPERFAMILY SSF46894 122 191 2.62E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 Gene3D G3DSA:3.40.50.2300 1 127 5.0E-31 T 14-10-2018 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 ProSitePatterns PS00622 LuxR-type HTH domain signature. 145 172 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 Pfam PF00196 Bacterial regulatory proteins, luxR family 130 183 7.7E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 161 1.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 173 1.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 131 145 1.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 Gene3D G3DSA:1.10.10.10 128 191 1.2E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 SMART SM00421 128 185 1.9E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 SMART SM00448 1 113 3.7E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0905 6ac1bacb2efb6487bc5446e09fa8e30b 192 SUPERFAMILY SSF52172 2 125 1.85E-31 T 14-10-2018 IPR011006 CheY-like superfamily Theos_1302 01711c9638de20ab180067e2887f9ae8 395 Pfam PF00589 Phage integrase family 187 372 1.1E-30 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Theos_1302 01711c9638de20ab180067e2887f9ae8 395 Gene3D G3DSA:1.10.443.10 186 381 2.0E-52 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Theos_1302 01711c9638de20ab180067e2887f9ae8 395 SUPERFAMILY SSF56349 71 375 2.85E-67 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Theos_1302 01711c9638de20ab180067e2887f9ae8 395 Gene3D G3DSA:1.10.150.130 65 183 5.0E-20 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Theos_0233 66e6df8cd564bd2739be3e892e1f745d 238 SUPERFAMILY SSF51735 9 185 2.68E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0233 66e6df8cd564bd2739be3e892e1f745d 238 Pfam PF00106 short chain dehydrogenase 15 141 5.1E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0233 66e6df8cd564bd2739be3e892e1f745d 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.7E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0233 66e6df8cd564bd2739be3e892e1f745d 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.7E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0233 66e6df8cd564bd2739be3e892e1f745d 238 Gene3D G3DSA:3.40.50.720 3 220 1.1E-26 T 14-10-2018 Theos_1310 7068f8b09697a08886e4550722f67953 339 SUPERFAMILY SSF57783 10 54 9.86E-5 T 14-10-2018 Theos_1310 7068f8b09697a08886e4550722f67953 339 Gene3D G3DSA:3.40.1360.10 224 328 2.1E-6 T 14-10-2018 Theos_1310 7068f8b09697a08886e4550722f67953 339 Pfam PF13362 Toprim domain 232 317 2.6E-16 T 14-10-2018 IPR006171 TOPRIM domain Theos_0234 fc821494b81e821c06ecd528e3059514 159 Pfam PF01661 Macro domain 20 129 5.9E-32 T 14-10-2018 IPR002589 Macro domain Theos_0234 fc821494b81e821c06ecd528e3059514 159 Gene3D G3DSA:3.40.220.10 1 159 3.3E-60 T 14-10-2018 Theos_0234 fc821494b81e821c06ecd528e3059514 159 SMART SM00506 3 129 6.3E-33 T 14-10-2018 IPR002589 Macro domain Theos_0234 fc821494b81e821c06ecd528e3059514 159 SUPERFAMILY SSF52949 3 158 2.52E-45 T 14-10-2018 Theos_0585 197eb19b26243d8a46896ee0028394f7 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 49 252 1.2E-62 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Theos_0585 197eb19b26243d8a46896ee0028394f7 261 Gene3D G3DSA:3.90.850.10 45 259 2.4E-86 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Theos_0585 197eb19b26243d8a46896ee0028394f7 261 Pfam PF10370 Domain of unknown function (DUF2437) 1 44 2.9E-8 T 14-10-2018 IPR018833 Domain of unknown function DUF2437 Theos_0585 197eb19b26243d8a46896ee0028394f7 261 SUPERFAMILY SSF56529 47 256 1.22E-74 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Theos_0585 197eb19b26243d8a46896ee0028394f7 261 Gene3D G3DSA:2.30.30.370 1 44 2.5E-31 T 14-10-2018 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 Gene3D G3DSA:1.10.1370.30 1 509 1.7E-211 T 14-10-2018 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 SUPERFAMILY SSF55486 5 505 6.38E-111 T 14-10-2018 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 303 319 3.7E-87 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 412 433 3.7E-87 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 343 362 3.7E-87 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 457 475 3.7E-87 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 256 275 3.7E-87 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 159 179 3.7E-87 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 276 295 3.7E-87 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 389 406 3.7E-87 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 239 255 3.7E-87 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 18 505 1.0E-114 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0026 a1163c13c0a4f0a0b5659141f76d815b 511 PIRSF PIRSF006615 2 511 4.0E-193 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Theos_0384 a1c58c17f039d237f1abd0e7a0f51bce 186 SMART SM00867 19 184 1.7E-12 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Theos_0384 a1c58c17f039d237f1abd0e7a0f51bce 186 Pfam PF04264 YceI-like domain 39 182 1.8E-17 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Theos_0384 a1c58c17f039d237f1abd0e7a0f51bce 186 Gene3D G3DSA:2.40.128.110 23 185 1.2E-22 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Theos_0384 a1c58c17f039d237f1abd0e7a0f51bce 186 SUPERFAMILY SSF101874 38 185 2.09E-19 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Theos_1765 350f37929d2131174d7824857ba3eea8 147 SUPERFAMILY SSF46785 4 132 1.92E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1765 350f37929d2131174d7824857ba3eea8 147 Pfam PF02082 Transcriptional regulator 1 82 2.8E-26 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Theos_1765 350f37929d2131174d7824857ba3eea8 147 Gene3D G3DSA:1.10.10.10 1 142 3.6E-47 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1765 350f37929d2131174d7824857ba3eea8 147 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 2.3E-42 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Theos_2414 33bb8fd676e88be14cbffadba6233b56 1161 Gene3D G3DSA:3.40.50.10810 101 372 3.0E-61 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Theos_2414 33bb8fd676e88be14cbffadba6233b56 1161 Pfam PF00271 Helicase conserved C-terminal domain 501 602 2.9E-20 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_2414 33bb8fd676e88be14cbffadba6233b56 1161 Pfam PF00176 SNF2 family N-terminal domain 125 355 1.7E-15 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Theos_2414 33bb8fd676e88be14cbffadba6233b56 1161 Gene3D G3DSA:3.40.50.300 432 632 1.6E-43 T 14-10-2018 Theos_2414 33bb8fd676e88be14cbffadba6233b56 1161 SMART SM00490 514 602 6.7E-26 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_2414 33bb8fd676e88be14cbffadba6233b56 1161 Pfam PF13020 Domain of unknown function (DUF3883) 1045 1128 6.9E-16 T 14-10-2018 IPR024975 Domain of unknown function DUF3883 Theos_2414 33bb8fd676e88be14cbffadba6233b56 1161 SUPERFAMILY SSF52540 223 642 3.25E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2414 33bb8fd676e88be14cbffadba6233b56 1161 SUPERFAMILY SSF52540 91 311 1.42E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2414 33bb8fd676e88be14cbffadba6233b56 1161 SMART SM00487 100 305 3.1E-21 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_1368 f96d5c286c79f6fe45e7cbbd69bbc5c9 339 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 337 2.4E-123 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Theos_1368 f96d5c286c79f6fe45e7cbbd69bbc5c9 339 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 138 154 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Theos_1368 f96d5c286c79f6fe45e7cbbd69bbc5c9 339 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 336 1.2E-122 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Theos_1368 f96d5c286c79f6fe45e7cbbd69bbc5c9 339 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 5 339 45.742 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Theos_1368 f96d5c286c79f6fe45e7cbbd69bbc5c9 339 Gene3D G3DSA:3.20.20.210 3 339 1.7E-134 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Theos_1368 f96d5c286c79f6fe45e7cbbd69bbc5c9 339 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 21 30 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Theos_1368 f96d5c286c79f6fe45e7cbbd69bbc5c9 339 SUPERFAMILY SSF51726 6 337 1.31E-104 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 Gene3D G3DSA:3.40.50.10810 337 502 1.2E-15 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 Gene3D G3DSA:3.30.870.10 4 218 9.4E-21 T 14-10-2018 Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 Gene3D G3DSA:3.40.50.10810 239 336 1.6E-5 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 SMART SM00490 723 836 2.7E-8 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 Gene3D G3DSA:3.40.50.300 666 857 1.4E-27 T 14-10-2018 Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 SMART SM00487 255 424 6.1E-11 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 Pfam PF13091 PLD-like domain 21 195 1.7E-13 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 SUPERFAMILY SSF52540 225 446 3.5E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 Pfam PF00176 SNF2 family N-terminal domain 346 410 1.1E-8 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 SUPERFAMILY SSF56024 10 204 1.26E-8 T 14-10-2018 Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 SUPERFAMILY SSF52540 352 851 2.97E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2551 fd4de998ff84f479de0a8e165815a9d1 1123 Pfam PF00271 Helicase conserved C-terminal domain 719 836 3.1E-13 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_2386 5a8d34e6bc3fba43634ed76259e00a4a 174 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 15 89 1.9E-10 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Theos_2386 5a8d34e6bc3fba43634ed76259e00a4a 174 SMART SM00855 14 124 1.5E-7 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Theos_2386 5a8d34e6bc3fba43634ed76259e00a4a 174 Gene3D G3DSA:3.40.50.1240 14 172 1.5E-28 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_2386 5a8d34e6bc3fba43634ed76259e00a4a 174 SUPERFAMILY SSF53254 14 163 1.46E-20 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 Pfam PF06470 SMC proteins Flexible Hinge Domain 444 558 3.7E-23 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 Gene3D G3DSA:3.40.50.300 5 231 8.0E-33 T 14-10-2018 Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 SMART SM00968 444 559 6.0E-30 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 SUPERFAMILY SSF75553 413 605 7.06E-36 T 14-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 PIRSF PIRSF005719 660 1006 2.0E-47 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 PIRSF PIRSF005719 4 307 7.0E-62 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 PIRSF PIRSF005719 319 643 5.3E-44 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 Gene3D G3DSA:3.30.70.1620 503 587 3.1E-37 T 14-10-2018 Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 Gene3D G3DSA:3.40.50.300 794 1004 3.7E-30 T 14-10-2018 Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 992 4.6E-43 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 SUPERFAMILY SSF52540 4 993 1.95E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0912 5f371c0229b1b95c66d8e70756c77355 1006 Gene3D G3DSA:1.20.1060.20 439 592 3.1E-37 T 14-10-2018 Theos_2005 0a3f7a37c66bb464c1684bd09c2c1f67 396 SUPERFAMILY SSF103473 12 392 9.29E-28 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_2005 0a3f7a37c66bb464c1684bd09c2c1f67 396 Pfam PF07690 Major Facilitator Superfamily 250 387 1.6E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_2005 0a3f7a37c66bb464c1684bd09c2c1f67 396 Gene3D G3DSA:1.20.1250.20 7 390 3.7E-23 T 14-10-2018 Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 481 4.8E-162 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 SUPERFAMILY SSF54631 68 205 3.66E-31 T 14-10-2018 Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 SMART SM00116 160 208 7.6E-12 T 14-10-2018 IPR000644 CBS domain Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 SMART SM00116 98 146 3.1E-14 T 14-10-2018 IPR000644 CBS domain Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 SMART SM01240 9 481 0.0 T 14-10-2018 Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 Pfam PF00571 CBS domain 151 206 2.8E-12 T 14-10-2018 IPR000644 CBS domain Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 Pfam PF00571 CBS domain 95 142 6.4E-13 T 14-10-2018 IPR000644 CBS domain Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 462 9.3E-187 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 SUPERFAMILY SSF51412 5 485 1.1E-127 T 14-10-2018 Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 Gene3D G3DSA:3.20.20.70 1 494 8.2E-220 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 PIRSF PIRSF000130 1 494 3.4E-208 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Theos_1632 87289b75c03b248bb0790b2f9bcb29d9 494 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 494 85.451 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Theos_2088 47351b0884f43788f12d4ecf002c86b8 131 Pfam PF01402 Ribbon-helix-helix protein, copG family 12 47 2.1E-6 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 Pfam PF02867 Ribonucleotide reductase, barrel domain 86 208 2.7E-24 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 Gene3D G3DSA:3.20.70.20 15 208 1.6E-38 T 14-10-2018 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 Pfam PF02867 Ribonucleotide reductase, barrel domain 387 537 3.8E-32 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 Gene3D G3DSA:3.20.70.20 209 547 4.3E-89 T 14-10-2018 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 Pfam PF02867 Ribonucleotide reductase, barrel domain 211 373 9.6E-21 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 TIGRFAM TIGR02510 NrdE-prime: ribonucleoside-diphosphate reductase, alpha chain 6 560 3.6E-282 T 14-10-2018 IPR013350 Ribonucleotide reductase alpha chain Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 PRINTS PR01183 Ribonucleotide reductase large chain signature 354 377 3.2E-13 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 PRINTS PR01183 Ribonucleotide reductase large chain signature 390 417 3.2E-13 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 PRINTS PR01183 Ribonucleotide reductase large chain signature 159 178 3.2E-13 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 PRINTS PR01183 Ribonucleotide reductase large chain signature 326 348 3.2E-13 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_2351 b68f579547c3f68d204ad8be1ca203e6 560 SUPERFAMILY SSF51998 84 539 1.28E-108 T 14-10-2018 Theos_0249 a98d38d4b439b5d007a1fb92216a7322 307 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Theos_0249 a98d38d4b439b5d007a1fb92216a7322 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 296 6.4E-76 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Theos_0249 a98d38d4b439b5d007a1fb92216a7322 307 Gene3D G3DSA:3.40.50.1100 16 302 1.7E-114 T 14-10-2018 Theos_0249 a98d38d4b439b5d007a1fb92216a7322 307 Gene3D G3DSA:3.40.50.1100 50 143 1.7E-114 T 14-10-2018 Theos_0249 a98d38d4b439b5d007a1fb92216a7322 307 SUPERFAMILY SSF53686 4 305 7.33E-88 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 Pfam PF10415 Fumarase C C-terminus 408 460 7.1E-23 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 462 88.761 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 Gene3D G3DSA:1.10.40.30 405 466 4.9E-29 T 14-10-2018 Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 Pfam PF00206 Lyase 11 342 1.1E-109 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 Gene3D G3DSA:1.10.275.10 1 138 1.3E-62 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 Gene3D G3DSA:1.20.200.10 139 404 1.5E-114 T 14-10-2018 Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 SUPERFAMILY SSF48557 3 458 1.73E-155 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 1.8E-32 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 1.8E-32 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 1.8E-32 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 1.8E-32 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0784 0b8d9d938f6321174d47ed82bc1ef66a 466 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 457 2.0E-209 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Theos_0667 3e24478ab579f541f8ab1a0c7967cbcc 399 SUPERFAMILY SSF53383 5 392 3.16E-106 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0667 3e24478ab579f541f8ab1a0c7967cbcc 399 Gene3D G3DSA:3.90.1150.10 22 390 1.7E-154 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0667 3e24478ab579f541f8ab1a0c7967cbcc 399 Pfam PF00155 Aminotransferase class I and II 50 386 2.2E-40 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Theos_0667 3e24478ab579f541f8ab1a0c7967cbcc 399 Gene3D G3DSA:3.40.640.10 69 285 1.7E-154 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 PRINTS PR00127 Clp protease catalytic subunit P signature 58 78 6.8E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 PRINTS PR00127 Clp protease catalytic subunit P signature 167 186 6.8E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 PRINTS PR00127 Clp protease catalytic subunit P signature 18 33 6.8E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 PRINTS PR00127 Clp protease catalytic subunit P signature 89 106 6.8E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 PRINTS PR00127 Clp protease catalytic subunit P signature 110 129 6.8E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 89 100 - T 14-10-2018 IPR018215 ClpP, Ser active site Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 111 124 - T 14-10-2018 IPR033135 ClpP, histidine active site Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 Gene3D G3DSA:3.90.226.10 1 194 1.2E-85 T 14-10-2018 Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 2 191 8.0E-95 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 Pfam PF00574 Clp protease 12 191 1.6E-85 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 2 192 43.789 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Theos_1347 90b720e69004726de0613e9c11d7c8d1 194 SUPERFAMILY SSF52096 10 193 4.25E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_1426 6f99e7344f303732154b75baa131b45b 358 SUPERFAMILY SSF54826 4 123 1.28E-18 T 14-10-2018 Theos_1426 6f99e7344f303732154b75baa131b45b 358 Pfam PF13378 Enolase C-terminal domain-like 144 307 3.9E-26 T 14-10-2018 IPR029065 Enolase C-terminal domain-like Theos_1426 6f99e7344f303732154b75baa131b45b 358 SUPERFAMILY SSF51604 128 341 2.88E-40 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Theos_1426 6f99e7344f303732154b75baa131b45b 358 SMART SM00922 141 236 1.7E-17 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Theos_1426 6f99e7344f303732154b75baa131b45b 358 Gene3D G3DSA:3.20.20.120 116 327 7.5E-68 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Theos_1426 6f99e7344f303732154b75baa131b45b 358 Gene3D G3DSA:3.30.390.10 4 115 7.5E-68 T 14-10-2018 IPR029017 Enolase-like, N-terminal Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 SUPERFAMILY SSF49493 95 241 7.85E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 346 34.97 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 PRINTS PR00625 DnaJ domain signature 40 60 2.0E-23 T 14-10-2018 IPR001623 DnaJ domain Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 PRINTS PR00625 DnaJ domain signature 23 38 2.0E-23 T 14-10-2018 IPR001623 DnaJ domain Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 PRINTS PR00625 DnaJ domain signature 5 23 2.0E-23 T 14-10-2018 IPR001623 DnaJ domain Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 SMART SM00271 2 60 2.9E-35 T 14-10-2018 IPR001623 DnaJ domain Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 Gene3D G3DSA:2.10.230.10 128 188 8.8E-33 T 14-10-2018 Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 Pfam PF00226 DnaJ domain 3 65 1.5E-30 T 14-10-2018 IPR001623 DnaJ domain Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 Pfam PF01556 DnaJ C terminal domain 101 312 1.4E-32 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 SUPERFAMILY SSF49493 238 323 3.01E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 Pfam PF00684 DnaJ central domain 128 188 1.1E-10 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 14-10-2018 IPR018253 DnaJ domain, conserved site Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 Gene3D G3DSA:2.60.260.20 98 228 8.8E-33 T 14-10-2018 Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 SUPERFAMILY SSF46565 1 89 1.7E-32 T 14-10-2018 IPR036869 Chaperone J-domain superfamily Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 SUPERFAMILY SSF57938 115 191 1.31E-14 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 Gene3D G3DSA:2.60.260.20 233 337 7.2E-24 T 14-10-2018 Theos_2073 3fb7e298427233acf083d4b8c834d6aa 349 Gene3D G3DSA:1.10.287.110 1 97 3.8E-33 T 14-10-2018 IPR036869 Chaperone J-domain superfamily Theos_0657 1f6745f7a3d44549cbe6e43423aa8397 187 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 Theos_0657 1f6745f7a3d44549cbe6e43423aa8397 187 Pfam PF01195 Peptidyl-tRNA hydrolase 3 170 2.4E-48 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Theos_0657 1f6745f7a3d44549cbe6e43423aa8397 187 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 173 31.731 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Theos_0657 1f6745f7a3d44549cbe6e43423aa8397 187 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 178 2.3E-48 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Theos_0657 1f6745f7a3d44549cbe6e43423aa8397 187 SUPERFAMILY SSF53178 1 181 7.32E-56 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 Theos_0657 1f6745f7a3d44549cbe6e43423aa8397 187 Gene3D G3DSA:3.40.50.1470 1 183 4.8E-58 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 Theos_1160 1e28236d2f6694284eec15473929fc84 162 Pfam PF03061 Thioesterase superfamily 54 136 4.7E-9 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Theos_1160 1e28236d2f6694284eec15473929fc84 162 Gene3D G3DSA:3.10.129.10 1 150 5.4E-38 T 14-10-2018 Theos_1160 1e28236d2f6694284eec15473929fc84 162 SUPERFAMILY SSF54637 2 146 8.7E-32 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_0641 4d8f1b6f6ff1f2b87673c49cda9fee17 401 SUPERFAMILY SSF52507 3 177 1.31E-48 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Theos_0641 4d8f1b6f6ff1f2b87673c49cda9fee17 401 Gene3D G3DSA:3.40.50.1950 1 182 5.1E-46 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Theos_0641 4d8f1b6f6ff1f2b87673c49cda9fee17 401 Gene3D G3DSA:3.40.50.10300 183 396 1.5E-76 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Theos_0641 4d8f1b6f6ff1f2b87673c49cda9fee17 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 183 365 1.8E-66 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Theos_0641 4d8f1b6f6ff1f2b87673c49cda9fee17 401 Pfam PF02441 Flavoprotein 3 176 1.6E-39 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 Theos_0641 4d8f1b6f6ff1f2b87673c49cda9fee17 401 SUPERFAMILY SSF102645 181 395 5.1E-72 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Theos_0641 4d8f1b6f6ff1f2b87673c49cda9fee17 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 390 8.3E-113 T 14-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 Gene3D G3DSA:3.10.350.10 66 112 1.1E-18 T 14-10-2018 IPR036779 LysM domain superfamily Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 Gene3D G3DSA:3.10.350.10 16 62 3.8E-20 T 14-10-2018 IPR036779 LysM domain superfamily Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 SUPERFAMILY SSF54106 18 61 8.89E-12 T 14-10-2018 Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 Pfam PF01476 LysM domain 20 61 1.4E-13 T 14-10-2018 IPR018392 LysM domain Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 Pfam PF01476 LysM domain 69 111 3.7E-14 T 14-10-2018 IPR018392 LysM domain Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 Pfam PF00877 NlpC/P60 family 145 248 1.2E-23 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 Gene3D G3DSA:3.90.1720.10 130 250 4.9E-33 T 14-10-2018 Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 SUPERFAMILY SSF54106 68 111 2.09E-11 T 14-10-2018 Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 SUPERFAMILY SSF54001 136 249 3.04E-34 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 SMART SM00257 19 62 2.2E-16 T 14-10-2018 IPR018392 LysM domain Theos_1918 9d45ad3b39de8c957c451f26d042c153 256 SMART SM00257 68 111 2.2E-16 T 14-10-2018 IPR018392 LysM domain Theos_0931 81f73c454bcd187c8f6ec25dcea01f8b 492 Gene3D G3DSA:1.10.132.100 363 492 6.5E-28 T 14-10-2018 Theos_0931 81f73c454bcd187c8f6ec25dcea01f8b 492 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 5 454 3.2E-109 T 14-10-2018 IPR013381 CRISPR-associated protein Cse1 Theos_0931 81f73c454bcd187c8f6ec25dcea01f8b 492 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 5 459 2.1E-97 T 14-10-2018 IPR013381 CRISPR-associated protein Cse1 Theos_1354 66d421a694d0111270adcbace8f5b3b0 254 SUPERFAMILY SSF53335 7 250 1.23E-57 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1354 66d421a694d0111270adcbace8f5b3b0 254 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 75 229 1.8E-15 T 14-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 Theos_1354 66d421a694d0111270adcbace8f5b3b0 254 Gene3D G3DSA:3.10.330.20 1 60 1.5E-19 T 14-10-2018 Theos_1354 66d421a694d0111270adcbace8f5b3b0 254 PIRSF PIRSF017269 2 254 7.0E-57 T 14-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 Theos_1354 66d421a694d0111270adcbace8f5b3b0 254 Gene3D G3DSA:3.40.50.150 61 237 8.8E-58 T 14-10-2018 Theos_0944 a94592b9e199b519797596901b31fe00 424 Gene3D G3DSA:3.40.640.10 71 319 4.3E-178 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0944 a94592b9e199b519797596901b31fe00 424 Gene3D G3DSA:3.90.1150.10 10 419 4.3E-178 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0944 a94592b9e199b519797596901b31fe00 424 Pfam PF00202 Aminotransferase class-III 38 424 2.6E-73 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0944 a94592b9e199b519797596901b31fe00 424 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 271 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0944 a94592b9e199b519797596901b31fe00 424 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 423 2.7E-181 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 Theos_0944 a94592b9e199b519797596901b31fe00 424 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 424 100.077 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 Theos_0944 a94592b9e199b519797596901b31fe00 424 SUPERFAMILY SSF53383 2 424 1.41E-131 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_1222 c89bf971a8187815b695973088a71cb7 200 SMART SM01207 8 184 7.0E-76 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_1222 c89bf971a8187815b695973088a71cb7 200 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 192 19.708 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_1222 c89bf971a8187815b695973088a71cb7 200 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 193 1.1E-52 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_1222 c89bf971a8187815b695973088a71cb7 200 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 183 5.7E-48 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_1644 47d5bd2f131d555ecf8f739c1cbbf028 322 SUPERFAMILY SSF56655 2 313 1.68E-108 T 14-10-2018 Theos_1644 47d5bd2f131d555ecf8f739c1cbbf028 322 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 5 310 1.9E-139 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Theos_1644 47d5bd2f131d555ecf8f739c1cbbf028 322 Gene3D G3DSA:3.40.190.90 123 284 1.1E-133 T 14-10-2018 Theos_1644 47d5bd2f131d555ecf8f739c1cbbf028 322 Gene3D G3DSA:3.30.540.10 9 310 1.1E-133 T 14-10-2018 Theos_1644 47d5bd2f131d555ecf8f739c1cbbf028 322 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 4 320 1.3E-114 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Theos_1644 47d5bd2f131d555ecf8f739c1cbbf028 322 PIRSF PIRSF004532 3 320 6.2E-135 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Theos_2141 41c5b8b519db36fa48c15654990ab154 277 Pfam PF00582 Universal stress protein family 2 133 1.2E-10 T 14-10-2018 IPR006016 UspA Theos_2141 41c5b8b519db36fa48c15654990ab154 277 Pfam PF00582 Universal stress protein family 143 272 1.6E-10 T 14-10-2018 IPR006016 UspA Theos_2141 41c5b8b519db36fa48c15654990ab154 277 PRINTS PR01438 Universal stress protein signature 141 159 2.8E-6 T 14-10-2018 IPR006015 Universal stress protein A Theos_2141 41c5b8b519db36fa48c15654990ab154 277 PRINTS PR01438 Universal stress protein signature 250 272 2.8E-6 T 14-10-2018 IPR006015 Universal stress protein A Theos_2141 41c5b8b519db36fa48c15654990ab154 277 PRINTS PR01438 Universal stress protein signature 233 245 2.8E-6 T 14-10-2018 IPR006015 Universal stress protein A Theos_2141 41c5b8b519db36fa48c15654990ab154 277 Gene3D G3DSA:3.40.50.620 1 133 1.3E-14 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_2141 41c5b8b519db36fa48c15654990ab154 277 SUPERFAMILY SSF52402 142 272 7.12E-14 T 14-10-2018 Theos_2141 41c5b8b519db36fa48c15654990ab154 277 SUPERFAMILY SSF52402 2 134 2.34E-15 T 14-10-2018 Theos_2141 41c5b8b519db36fa48c15654990ab154 277 Gene3D G3DSA:3.40.50.620 139 271 9.5E-14 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1517 f7505a10b67cc6e2dc1f9ce239c64e5b 332 PIRSF PIRSF000164 1 307 6.8E-37 T 14-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Theos_1517 f7505a10b67cc6e2dc1f9ce239c64e5b 332 Gene3D G3DSA:3.20.20.70 1 309 7.4E-54 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1517 f7505a10b67cc6e2dc1f9ce239c64e5b 332 SUPERFAMILY SSF51395 2 306 3.66E-58 T 14-10-2018 Theos_1517 f7505a10b67cc6e2dc1f9ce239c64e5b 332 Pfam PF01180 Dihydroorotate dehydrogenase 95 290 1.3E-9 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Theos_1376 fb958088cb789799c96aabba1606ba61 198 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 177 188 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1376 fb958088cb789799c96aabba1606ba61 198 SUPERFAMILY SSF54862 67 194 2.23E-21 T 14-10-2018 Theos_1376 fb958088cb789799c96aabba1606ba61 198 Gene3D G3DSA:3.30.70.20 112 194 4.5E-20 T 14-10-2018 Theos_1376 fb958088cb789799c96aabba1606ba61 198 SUPERFAMILY SSF54292 1 90 3.75E-20 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Theos_1376 fb958088cb789799c96aabba1606ba61 198 Pfam PF13187 4Fe-4S dicluster domain 132 191 3.9E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1376 fb958088cb789799c96aabba1606ba61 198 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 68 8.1E-12 T 14-10-2018 Theos_1376 fb958088cb789799c96aabba1606ba61 198 Gene3D G3DSA:3.10.20.740 1 98 1.8E-20 T 14-10-2018 Theos_1125 ef92814557dd76cccf5bf768cb652786 415 SUPERFAMILY SSF53623 57 279 3.66E-35 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_1125 ef92814557dd76cccf5bf768cb652786 415 Gene3D G3DSA:3.90.190.20 269 403 2.4E-27 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_1125 ef92814557dd76cccf5bf768cb652786 415 Pfam PF08245 Mur ligase middle domain 98 228 1.3E-23 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Theos_1125 ef92814557dd76cccf5bf768cb652786 415 Gene3D G3DSA:3.40.50.720 1 81 1.2E-11 T 14-10-2018 Theos_1125 ef92814557dd76cccf5bf768cb652786 415 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 1 405 26.262 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Theos_1125 ef92814557dd76cccf5bf768cb652786 415 SUPERFAMILY SSF51984 2 82 1.8E-8 T 14-10-2018 Theos_1125 ef92814557dd76cccf5bf768cb652786 415 SUPERFAMILY SSF53244 266 405 5.49E-28 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_1125 ef92814557dd76cccf5bf768cb652786 415 Gene3D G3DSA:3.40.1190.10 83 251 7.0E-39 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_2450 1b211087aa4087bc2ed8397222ecf14b 475 Pfam PF00171 Aldehyde dehydrogenase family 15 469 4.8E-143 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Theos_2450 1b211087aa4087bc2ed8397222ecf14b 475 SUPERFAMILY SSF53720 2 474 2.62E-145 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_2450 1b211087aa4087bc2ed8397222ecf14b 475 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 475 7.6E-171 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 Theos_2450 1b211087aa4087bc2ed8397222ecf14b 475 Gene3D G3DSA:3.40.605.10 18 452 1.7E-151 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_2450 1b211087aa4087bc2ed8397222ecf14b 475 Gene3D G3DSA:3.40.309.10 246 444 1.7E-151 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Theos_2450 1b211087aa4087bc2ed8397222ecf14b 475 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 271 282 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 Gene3D G3DSA:3.30.465.10 352 438 1.0E-25 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 Pfam PF03471 Transporter associated domain 361 436 1.2E-24 T 14-10-2018 IPR005170 Transporter-associated domain Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 SUPERFAMILY SSF54631 218 358 5.05E-37 T 14-10-2018 Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 SMART SM01091 360 438 1.3E-30 T 14-10-2018 IPR005170 Transporter-associated domain Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 SUPERFAMILY SSF56176 359 444 1.94E-24 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 Pfam PF00571 CBS domain 223 279 1.0E-7 T 14-10-2018 IPR000644 CBS domain Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 Pfam PF00571 CBS domain 294 344 5.3E-7 T 14-10-2018 IPR000644 CBS domain Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 SMART SM00116 232 281 0.15 T 14-10-2018 IPR000644 CBS domain Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 SMART SM00116 296 344 3.7 T 14-10-2018 IPR000644 CBS domain Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 Pfam PF01595 Domain of unknown function DUF21 34 208 9.0E-48 T 14-10-2018 IPR002550 CNNM, transmembrane domain Theos_1416 30ab02a6ce605eaa84384f30848311d8 447 Gene3D G3DSA:3.10.580.10 202 351 1.2E-58 T 14-10-2018 Theos_1252 b488898f9f0bf881ca26c2c36890718c 179 SUPERFAMILY SSF52980 4 177 1.66E-21 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_1252 b488898f9f0bf881ca26c2c36890718c 179 Pfam PF05685 Putative restriction endonuclease 9 171 7.7E-30 T 14-10-2018 IPR008538 Domain of unknown function DUF820 Theos_1252 b488898f9f0bf881ca26c2c36890718c 179 Gene3D G3DSA:3.90.1570.10 1 178 4.2E-17 T 14-10-2018 Theos_0634 d6557815e2510a8d8500c794c23b87a9 203 SUPERFAMILY SSF51206 1 130 3.01E-26 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Theos_0634 d6557815e2510a8d8500c794c23b87a9 203 SUPERFAMILY SSF46785 134 201 7.76E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0634 d6557815e2510a8d8500c794c23b87a9 203 Gene3D G3DSA:1.10.10.10 133 201 5.8E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0634 d6557815e2510a8d8500c794c23b87a9 203 SMART SM00100 1 117 1.9E-18 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_0634 d6557815e2510a8d8500c794c23b87a9 203 SMART SM00419 145 192 1.4E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_0634 d6557815e2510a8d8500c794c23b87a9 203 Pfam PF00027 Cyclic nucleotide-binding domain 20 102 1.3E-17 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_0634 d6557815e2510a8d8500c794c23b87a9 203 Pfam PF13545 Crp-like helix-turn-helix domain 136 199 3.6E-17 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_0634 d6557815e2510a8d8500c794c23b87a9 203 Gene3D G3DSA:2.60.120.10 1 132 4.3E-27 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 26 101 4.8E-9 T 14-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 SUPERFAMILY SSF46626 230 324 7.45E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 Gene3D G3DSA:1.10.287.90 19 111 3.2E-31 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 140 211 5.7E-17 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 160 208 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 SUPERFAMILY SSF81464 25 109 6.87E-16 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 Pfam PF00034 Cytochrome c 237 325 9.9E-11 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 Gene3D G3DSA:2.60.40.2600 112 337 4.4E-90 T 14-10-2018 Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 SUPERFAMILY SSF49503 111 262 1.71E-49 T 14-10-2018 IPR008972 Cupredoxin Theos_0035 e240920820b10eb5d0a96e48b85da4d6 337 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 27 225 1.7E-70 T 14-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0010 92898b5a20aeab860584526718baeb17 304 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 201 275 2.2E-21 T 14-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal Theos_0010 92898b5a20aeab860584526718baeb17 304 Gene3D G3DSA:3.40.50.970 25 201 3.0E-21 T 14-10-2018 Theos_0010 92898b5a20aeab860584526718baeb17 304 SUPERFAMILY SSF52518 14 273 1.1E-75 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_0010 92898b5a20aeab860584526718baeb17 304 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 16 294 1.0E-131 T 14-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate Theos_0010 92898b5a20aeab860584526718baeb17 304 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 197 2.8E-28 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Theos_2408 84f1cba1312791fd8a2da4a8e081ef9d 324 Gene3D G3DSA:3.40.190.170 18 324 9.6E-99 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Theos_2408 84f1cba1312791fd8a2da4a8e081ef9d 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 29 309 1.2E-78 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Theos_0203 42a695e08a252e6e6894aae029ffc67d 361 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 203 209 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Theos_0203 42a695e08a252e6e6894aae029ffc67d 361 SUPERFAMILY SSF53335 2 287 4.27E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0203 42a695e08a252e6e6894aae029ffc67d 361 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 4 289 1.4E-30 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Theos_0203 42a695e08a252e6e6894aae029ffc67d 361 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 200 212 2.1E-6 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Theos_0203 42a695e08a252e6e6894aae029ffc67d 361 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 32 46 2.1E-6 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Theos_0203 42a695e08a252e6e6894aae029ffc67d 361 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 4 20 2.1E-6 T 14-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Theos_1554 a12656cfbe45d23132d61074207d2caf 90 Gene3D G3DSA:1.10.8.990 66 83 6.7E-6 T 14-10-2018 Theos_1554 a12656cfbe45d23132d61074207d2caf 90 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 6 89 2.1E-18 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Theos_1554 a12656cfbe45d23132d61074207d2caf 90 Gene3D G3DSA:1.10.20.60 1 45 6.0E-19 T 14-10-2018 Theos_1554 a12656cfbe45d23132d61074207d2caf 90 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 89 20.521 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Theos_1554 a12656cfbe45d23132d61074207d2caf 90 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 84 9.8E-16 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Theos_1554 a12656cfbe45d23132d61074207d2caf 90 SUPERFAMILY SSF141000 3 87 6.02E-20 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 Theos_1159 1f38427429ac304b62c0e8cd97a333b9 139 Gene3D G3DSA:3.40.50.280 1 137 2.5E-61 T 14-10-2018 Theos_1159 1f38427429ac304b62c0e8cd97a333b9 139 SUPERFAMILY SSF52242 2 131 1.31E-50 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Theos_1159 1f38427429ac304b62c0e8cd97a333b9 139 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 3 131 3.5E-52 T 14-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Theos_1159 1f38427429ac304b62c0e8cd97a333b9 139 Pfam PF02310 B12 binding domain 5 120 1.7E-24 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Theos_1844 2f4280f9b571a648214161f346300d73 217 SUPERFAMILY SSF56176 2 113 2.01E-13 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Theos_1844 2f4280f9b571a648214161f346300d73 217 Gene3D G3DSA:3.30.70.2560 115 169 1.1E-21 T 14-10-2018 Theos_1844 2f4280f9b571a648214161f346300d73 217 Gene3D G3DSA:3.30.465.10 1 114 7.0E-31 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Theos_1526 991fbfcc18b63ed49e6925ad611c5b28 137 Pfam PF00582 Universal stress protein family 1 137 1.2E-34 T 14-10-2018 IPR006016 UspA Theos_1526 991fbfcc18b63ed49e6925ad611c5b28 137 SUPERFAMILY SSF52402 2 137 3.42E-36 T 14-10-2018 Theos_1526 991fbfcc18b63ed49e6925ad611c5b28 137 Gene3D G3DSA:3.40.50.620 1 137 6.8E-45 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1526 991fbfcc18b63ed49e6925ad611c5b28 137 PRINTS PR01438 Universal stress protein signature 97 109 2.6E-21 T 14-10-2018 IPR006015 Universal stress protein A Theos_1526 991fbfcc18b63ed49e6925ad611c5b28 137 PRINTS PR01438 Universal stress protein signature 115 137 2.6E-21 T 14-10-2018 IPR006015 Universal stress protein A Theos_1526 991fbfcc18b63ed49e6925ad611c5b28 137 PRINTS PR01438 Universal stress protein signature 2 20 2.6E-21 T 14-10-2018 IPR006015 Universal stress protein A Theos_2147 59acea33f5fc13085252198d35c18cbc 767 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site Theos_2147 59acea33f5fc13085252198d35c18cbc 767 TIGRFAM TIGR03356 BGL: beta-galactosidase 6 372 1.4E-147 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 Theos_2147 59acea33f5fc13085252198d35c18cbc 767 Gene3D G3DSA:3.20.20.80 2 377 3.5E-140 T 14-10-2018 Theos_2147 59acea33f5fc13085252198d35c18cbc 767 SUPERFAMILY SSF51445 6 373 7.05E-131 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily Theos_2147 59acea33f5fc13085252198d35c18cbc 767 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 334 342 - T 14-10-2018 IPR018120 Glycoside hydrolase family 1, active site Theos_2147 59acea33f5fc13085252198d35c18cbc 767 Pfam PF00232 Glycosyl hydrolase family 1 6 372 1.0E-113 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_2147 59acea33f5fc13085252198d35c18cbc 767 SUPERFAMILY SSF52540 505 715 5.98E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2147 59acea33f5fc13085252198d35c18cbc 767 PRINTS PR00131 Glycosyl hydrolase family 1 signature 355 366 7.6E-7 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_2147 59acea33f5fc13085252198d35c18cbc 767 PRINTS PR00131 Glycosyl hydrolase family 1 signature 334 342 7.6E-7 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_2147 59acea33f5fc13085252198d35c18cbc 767 PRINTS PR00131 Glycosyl hydrolase family 1 signature 275 289 7.6E-7 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Theos_0600 7491b077cf3edf8f3dde2175fc49afe3 314 Gene3D G3DSA:2.30.140.10 3 54 1.1E-19 T 14-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Theos_0600 7491b077cf3edf8f3dde2175fc49afe3 314 SUPERFAMILY SSF53335 2 287 2.39E-78 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0600 7491b077cf3edf8f3dde2175fc49afe3 314 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 5 287 35.233 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Theos_0600 7491b077cf3edf8f3dde2175fc49afe3 314 Pfam PF17284 Spermidine synthase tetramerisation domain 5 57 3.2E-9 T 14-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Theos_0600 7491b077cf3edf8f3dde2175fc49afe3 314 Gene3D G3DSA:3.40.50.150 56 311 3.3E-92 T 14-10-2018 Theos_0600 7491b077cf3edf8f3dde2175fc49afe3 314 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 81 94 - T 14-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Theos_0600 7491b077cf3edf8f3dde2175fc49afe3 314 Pfam PF01564 Spermine/spermidine synthase domain 61 231 1.2E-44 T 14-10-2018 Theos_1663 9336b77a5bc5649374fff015a0820ab0 381 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 260 335 6.7E-21 T 14-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain Theos_1663 9336b77a5bc5649374fff015a0820ab0 381 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 35 113 2.5E-7 T 14-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain Theos_1793 ec6b04c52b5a4638de822eefa0ad419b 273 Gene3D G3DSA:1.10.12.10 215 272 4.2E-22 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Theos_1793 ec6b04c52b5a4638de822eefa0ad419b 273 Gene3D G3DSA:3.90.226.10 3 214 6.7E-77 T 14-10-2018 Theos_1793 ec6b04c52b5a4638de822eefa0ad419b 273 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 116 136 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Theos_1793 ec6b04c52b5a4638de822eefa0ad419b 273 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 272 2.2E-70 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Theos_1793 ec6b04c52b5a4638de822eefa0ad419b 273 SUPERFAMILY SSF52096 10 272 5.89E-95 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_2327 9321d0c33668ab2e622229b4d108426f 136 SMART SM00748 8 119 2.4E-36 T 14-10-2018 IPR007842 HEPN domain Theos_2327 9321d0c33668ab2e622229b4d108426f 136 SUPERFAMILY SSF81593 2 126 2.08E-40 T 14-10-2018 Theos_2327 9321d0c33668ab2e622229b4d108426f 136 Gene3D G3DSA:1.20.120.330 1 130 1.4E-37 T 14-10-2018 Theos_2327 9321d0c33668ab2e622229b4d108426f 136 Pfam PF05168 HEPN domain 5 125 1.5E-31 T 14-10-2018 IPR007842 HEPN domain Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 PRINTS PR00625 DnaJ domain signature 23 38 1.5E-26 T 14-10-2018 IPR001623 DnaJ domain Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 PRINTS PR00625 DnaJ domain signature 39 59 1.5E-26 T 14-10-2018 IPR001623 DnaJ domain Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 PRINTS PR00625 DnaJ domain signature 5 23 1.5E-26 T 14-10-2018 IPR001623 DnaJ domain Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 PRINTS PR00625 DnaJ domain signature 59 78 1.5E-26 T 14-10-2018 IPR001623 DnaJ domain Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 Pfam PF01556 DnaJ C terminal domain 119 257 2.7E-30 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 SUPERFAMILY SSF46565 1 106 1.22E-35 T 14-10-2018 IPR036869 Chaperone J-domain superfamily Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 SUPERFAMILY SSF49493 184 268 3.79E-19 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 SUPERFAMILY SSF49493 111 193 6.02E-17 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 SMART SM00271 2 59 2.2E-33 T 14-10-2018 IPR001623 DnaJ domain Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 ProSitePatterns PS00636 Nt-dnaJ domain signature. 44 63 - T 14-10-2018 IPR018253 DnaJ domain, conserved site Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 Gene3D G3DSA:2.60.260.20 113 178 2.3E-24 T 14-10-2018 Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 Gene3D G3DSA:1.10.287.110 1 111 5.1E-49 T 14-10-2018 IPR036869 Chaperone J-domain superfamily Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 Gene3D G3DSA:2.60.260.20 180 279 8.1E-32 T 14-10-2018 Theos_0684 c9a0fc1edea6fd5204554f0594dbb53e 279 Pfam PF00226 DnaJ domain 3 64 4.7E-29 T 14-10-2018 IPR001623 DnaJ domain Theos_1397 73bfeb1972c7b4d7eaa4ed71f24fcfe4 331 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 3 285 8.3E-82 T 14-10-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB Theos_1397 73bfeb1972c7b4d7eaa4ed71f24fcfe4 331 Pfam PF04230 Polysaccharide pyruvyl transferase 13 264 5.7E-40 T 14-10-2018 IPR007345 Polysaccharide pyruvyl transferase Theos_0928 7ceed86be7c8fb1b569144449382d3e3 168 SMART SM01207 6 160 1.0E-6 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_0928 7ceed86be7c8fb1b569144449382d3e3 168 Pfam PF02660 Glycerol-3-phosphate acyltransferase 37 150 1.2E-8 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 SUPERFAMILY SSF50447 464 563 2.47E-18 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 SUPERFAMILY SSF101353 256 468 2.35E-61 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 Gene3D G3DSA:2.40.30.130 473 563 1.4E-11 T 14-10-2018 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 SUPERFAMILY SSF55681 2 254 6.46E-88 T 14-10-2018 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 Gene3D G3DSA:3.10.310.40 777 874 1.1E-8 T 14-10-2018 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 Gene3D G3DSA:3.30.930.10 1 251 1.2E-95 T 14-10-2018 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 235 248 7.4E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 7.4E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 307 320 7.4E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 283 299 7.4E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 204 215 7.4E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 Pfam PF02272 DHHA1 domain 743 873 6.4E-16 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 164.46 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 663 707 7.8E-17 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 SMART SM00863 663 707 2.0E-17 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 Gene3D G3DSA:3.30.54.20 634 688 8.2E-53 T 14-10-2018 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 860 5.0E-267 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 Pfam PF01411 tRNA synthetases class II (A) 5 567 4.8E-213 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 SUPERFAMILY SSF55186 566 718 4.71E-50 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Theos_0118 c17eba801366afcb8df9c1b278f04d1f 874 Gene3D G3DSA:3.30.980.10 572 708 8.2E-53 T 14-10-2018 Theos_0303 ffb78e32a2f45ef6388ce2440b216274 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 8 124 9.4E-55 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0303 ffb78e32a2f45ef6388ce2440b216274 129 Gene3D G3DSA:3.30.420.80 1 129 4.5E-57 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 Theos_0303 ffb78e32a2f45ef6388ce2440b216274 129 SUPERFAMILY SSF53137 12 127 1.37E-44 T 14-10-2018 Theos_0303 ffb78e32a2f45ef6388ce2440b216274 129 Pfam PF00411 Ribosomal protein S11 17 126 2.8E-42 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Theos_0303 ffb78e32a2f45ef6388ce2440b216274 129 PIRSF PIRSF002131 1 127 3.2E-51 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Theos_0303 ffb78e32a2f45ef6388ce2440b216274 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 95 117 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site Theos_0303 ffb78e32a2f45ef6388ce2440b216274 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 127 30.263 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Theos_0328 5967753e84e06a9351936120aa94687e 237 Gene3D G3DSA:3.40.50.1000 4 204 1.9E-33 T 14-10-2018 IPR023214 HAD superfamily Theos_0328 5967753e84e06a9351936120aa94687e 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 140 203 1.6E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0328 5967753e84e06a9351936120aa94687e 237 SUPERFAMILY SSF56784 2 236 4.63E-33 T 14-10-2018 IPR036412 HAD-like superfamily Theos_0328 5967753e84e06a9351936120aa94687e 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 91 204 1.0E-12 T 14-10-2018 Theos_0328 5967753e84e06a9351936120aa94687e 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 168 7.4E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0328 5967753e84e06a9351936120aa94687e 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 170 190 7.4E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0328 5967753e84e06a9351936120aa94687e 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 7.4E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0328 5967753e84e06a9351936120aa94687e 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 43 56 7.4E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0328 5967753e84e06a9351936120aa94687e 237 Gene3D G3DSA:1.10.150.400 21 106 1.9E-33 T 14-10-2018 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 PIRSF PIRSF002560 1 156 1.5E-56 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 152 4.0E-51 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 PRINTS PR00601 Bacterioferritin signature 3 22 6.8E-44 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 PRINTS PR00601 Bacterioferritin signature 65 85 6.8E-44 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 PRINTS PR00601 Bacterioferritin signature 107 127 6.8E-44 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 PRINTS PR00601 Bacterioferritin signature 86 106 6.8E-44 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 PRINTS PR00601 Bacterioferritin signature 23 43 6.8E-44 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 PRINTS PR00601 Bacterioferritin signature 44 64 6.8E-44 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 PRINTS PR00601 Bacterioferritin signature 128 149 6.8E-44 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 Gene3D G3DSA:1.20.1260.10 1 154 3.6E-57 T 14-10-2018 IPR012347 Ferritin-like Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 SUPERFAMILY SSF47240 1 154 8.13E-45 T 14-10-2018 IPR009078 Ferritin-like superfamily Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Theos_1013 c88ffc9ec61d0e22cb060fd35291a2c3 159 Pfam PF00210 Ferritin-like domain 9 142 1.3E-32 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Theos_1234 d84f9e5245461af155c721e40490aac7 219 Pfam PF07798 Protein of unknown function (DUF1640) 75 199 1.3E-6 T 14-10-2018 IPR024461 Coiled-coil domain-containing protein 90-like Theos_1234 d84f9e5245461af155c721e40490aac7 219 Gene3D G3DSA:1.20.5.1230 2 205 5.3E-16 T 14-10-2018 Theos_1234 d84f9e5245461af155c721e40490aac7 219 SUPERFAMILY SSF58113 11 194 1.31E-16 T 14-10-2018 Theos_1234 d84f9e5245461af155c721e40490aac7 219 Pfam PF07902 gp58-like protein 42 176 2.4E-11 T 14-10-2018 IPR012892 Gp58-like Theos_2082 4262579047de2d2f31d0b740d1ee7801 483 Pfam PF13148 Protein of unknown function (DUF3987) 66 397 2.5E-64 T 14-10-2018 IPR025048 Protein of unknown function DUF3987) Theos_1511 a73c01516f2ffa50a18b42bbcf323290 313 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 188 271 4.3E-35 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 Theos_1511 a73c01516f2ffa50a18b42bbcf323290 313 SUPERFAMILY SSF52402 2 172 4.67E-30 T 14-10-2018 Theos_1511 a73c01516f2ffa50a18b42bbcf323290 313 SMART SM00893 2 184 1.2E-15 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Theos_1511 a73c01516f2ffa50a18b42bbcf323290 313 SUPERFAMILY SSF52467 186 307 3.72E-48 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Theos_1511 a73c01516f2ffa50a18b42bbcf323290 313 Pfam PF01012 Electron transfer flavoprotein domain 3 168 2.4E-24 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Theos_1511 a73c01516f2ffa50a18b42bbcf323290 313 Gene3D G3DSA:3.40.50.1220 182 313 8.5E-58 T 14-10-2018 Theos_1511 a73c01516f2ffa50a18b42bbcf323290 313 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 252 278 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 Theos_1511 a73c01516f2ffa50a18b42bbcf323290 313 Gene3D G3DSA:3.40.50.620 1 181 5.3E-29 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1511 a73c01516f2ffa50a18b42bbcf323290 313 PIRSF PIRSF000089 1 313 4.5E-92 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 Theos_2283 af12aba57e997c8640562a574d6c93a7 491 Gene3D G3DSA:3.40.50.410 305 445 5.3E-7 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_2283 af12aba57e997c8640562a574d6c93a7 491 SUPERFAMILY SSF53300 305 458 2.86E-11 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_2283 af12aba57e997c8640562a574d6c93a7 491 Pfam PF05731 TROVE domain 207 255 2.7E-6 T 14-10-2018 IPR008858 TROVE domain GO:0003723 Theos_2283 af12aba57e997c8640562a574d6c93a7 491 SUPERFAMILY SSF140864 6 281 1.07E-28 T 14-10-2018 IPR037214 TROVE domain superfamily Theos_0593 14e68827f520b847eae904189073ef4f 580 SMART SM00100 8 124 1.6E-9 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_0593 14e68827f520b847eae904189073ef4f 580 Gene3D G3DSA:2.60.120.10 2 126 4.2E-21 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_0593 14e68827f520b847eae904189073ef4f 580 Pfam PF00027 Cyclic nucleotide-binding domain 28 107 6.9E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_0593 14e68827f520b847eae904189073ef4f 580 Pfam PF00571 CBS domain 137 188 1.6E-9 T 14-10-2018 IPR000644 CBS domain Theos_0593 14e68827f520b847eae904189073ef4f 580 Pfam PF00571 CBS domain 199 249 2.3E-9 T 14-10-2018 IPR000644 CBS domain Theos_0593 14e68827f520b847eae904189073ef4f 580 SMART SM00116 206 253 8.0E-9 T 14-10-2018 IPR000644 CBS domain Theos_0593 14e68827f520b847eae904189073ef4f 580 SMART SM00116 144 189 3.7E-4 T 14-10-2018 IPR000644 CBS domain Theos_0593 14e68827f520b847eae904189073ef4f 580 SUPERFAMILY SSF51206 3 125 8.38E-22 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Theos_0593 14e68827f520b847eae904189073ef4f 580 SUPERFAMILY SSF54631 135 251 2.4E-28 T 14-10-2018 Theos_0593 14e68827f520b847eae904189073ef4f 580 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 439 577 1.0E-42 T 14-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding Theos_0593 14e68827f520b847eae904189073ef4f 580 Gene3D G3DSA:3.10.580.10 131 257 6.8E-33 T 14-10-2018 Theos_0593 14e68827f520b847eae904189073ef4f 580 Pfam PF03445 Putative nucleotidyltransferase DUF294 273 404 2.8E-43 T 14-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 Theos_1505 8974d6a2f70903226bd15bb0c7a35283 146 Pfam PF00582 Universal stress protein family 1 142 2.9E-33 T 14-10-2018 IPR006016 UspA Theos_1505 8974d6a2f70903226bd15bb0c7a35283 146 SUPERFAMILY SSF52402 2 142 4.27E-39 T 14-10-2018 Theos_1505 8974d6a2f70903226bd15bb0c7a35283 146 PRINTS PR01438 Universal stress protein signature 102 114 7.7E-18 T 14-10-2018 IPR006015 Universal stress protein A Theos_1505 8974d6a2f70903226bd15bb0c7a35283 146 PRINTS PR01438 Universal stress protein signature 2 20 7.7E-18 T 14-10-2018 IPR006015 Universal stress protein A Theos_1505 8974d6a2f70903226bd15bb0c7a35283 146 PRINTS PR01438 Universal stress protein signature 120 142 7.7E-18 T 14-10-2018 IPR006015 Universal stress protein A Theos_1505 8974d6a2f70903226bd15bb0c7a35283 146 Gene3D G3DSA:3.40.50.620 1 143 1.6E-39 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 PRINTS PR00773 GrpE protein signature 72 87 3.7E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 PRINTS PR00773 GrpE protein signature 148 167 3.7E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 PRINTS PR00773 GrpE protein signature 44 60 3.7E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 PRINTS PR00773 GrpE protein signature 124 139 3.7E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 Pfam PF01025 GrpE 12 168 4.8E-41 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 SUPERFAMILY SSF58014 24 116 6.54E-22 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 Gene3D G3DSA:3.90.20.20 2 115 5.5E-34 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 Gene3D G3DSA:2.30.22.10 116 177 9.1E-23 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 SUPERFAMILY SSF51064 117 170 4.84E-11 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Theos_0683 a5bd4766b1518ca46376ae5ade96923c 179 Hamap MF_01151 Protein GrpE [grpE]. 2 169 17.615 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Theos_0373 72bf03e702e7205511f8f249c3ca8aa9 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 1.9E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0373 72bf03e702e7205511f8f249c3ca8aa9 224 SUPERFAMILY SSF52172 1 172 1.66E-43 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0373 72bf03e702e7205511f8f249c3ca8aa9 224 Gene3D G3DSA:1.10.10.10 123 224 9.2E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0373 72bf03e702e7205511f8f249c3ca8aa9 224 SMART SM00448 4 114 5.0E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0373 72bf03e702e7205511f8f249c3ca8aa9 224 Gene3D G3DSA:3.40.50.2300 1 122 1.0E-38 T 14-10-2018 Theos_0373 72bf03e702e7205511f8f249c3ca8aa9 224 SMART SM00862 147 221 8.0E-29 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0373 72bf03e702e7205511f8f249c3ca8aa9 224 Pfam PF00072 Response regulator receiver domain 6 115 8.8E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_2245 7d9fabd766d0d54da5b21abb37c14121 185 Gene3D G3DSA:1.10.10.10 2 134 9.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2245 7d9fabd766d0d54da5b21abb37c14121 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 4.6E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_2245 7d9fabd766d0d54da5b21abb37c14121 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 4.6E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_2245 7d9fabd766d0d54da5b21abb37c14121 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 4.6E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_2245 7d9fabd766d0d54da5b21abb37c14121 185 SUPERFAMILY SSF46785 6 117 1.77E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2245 7d9fabd766d0d54da5b21abb37c14121 185 Pfam PF12802 MarR family 29 87 3.9E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_2245 7d9fabd766d0d54da5b21abb37c14121 185 SMART SM00347 24 122 4.2E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_0400 c85ba2e0e9e59996da7b892b6d8eab54 394 Gene3D G3DSA:1.10.3720.10 179 389 4.6E-16 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0400 c85ba2e0e9e59996da7b892b6d8eab54 394 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 207 393 1.0E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0400 c85ba2e0e9e59996da7b892b6d8eab54 394 SUPERFAMILY SSF161098 183 377 9.59E-18 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0400 c85ba2e0e9e59996da7b892b6d8eab54 394 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 68 9.2E-20 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Theos_0925 4da458e981b77be3a9238c6477033628 367 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 100 348 2.9E-19 T 14-10-2018 Theos_0925 4da458e981b77be3a9238c6477033628 367 Gene3D G3DSA:3.40.830.10 98 350 1.1E-26 T 14-10-2018 Theos_0925 4da458e981b77be3a9238c6477033628 367 Pfam PF01875 Memo-like protein 102 364 1.2E-50 T 14-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 Theos_1493 ec04a0da1780dd26866581944a180981 288 Pfam PF00491 Arginase family 15 274 7.7E-66 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Theos_1493 ec04a0da1780dd26866581944a180981 288 SUPERFAMILY SSF52768 6 277 7.2E-72 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily Theos_1493 ec04a0da1780dd26866581944a180981 288 Gene3D G3DSA:3.40.800.10 2 281 3.7E-74 T 14-10-2018 Theos_1493 ec04a0da1780dd26866581944a180981 288 TIGRFAM TIGR01230 agmatinase: agmatinase 4 275 2.3E-62 T 14-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 Theos_1493 ec04a0da1780dd26866581944a180981 288 PIRSF PIRSF036979 2 280 1.2E-59 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Theos_0530 f3f3f8be49af8cbf3118d78a8fa2dfd8 372 SUPERFAMILY SSF53756 1 365 1.81E-115 T 14-10-2018 Theos_0530 f3f3f8be49af8cbf3118d78a8fa2dfd8 372 Gene3D G3DSA:3.40.50.2000 6 349 3.7E-133 T 14-10-2018 Theos_0530 f3f3f8be49af8cbf3118d78a8fa2dfd8 372 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 355 2.7E-98 T 14-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Theos_0530 f3f3f8be49af8cbf3118d78a8fa2dfd8 372 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 356 1.7E-112 T 14-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 Theos_0530 f3f3f8be49af8cbf3118d78a8fa2dfd8 372 Gene3D G3DSA:3.40.50.2000 188 344 3.7E-133 T 14-10-2018 Theos_1010 140fe30a73ab80db2140acd69bf2bf5c 79 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 37 3.0E-4 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Theos_1805 a7ce9811a906f9665a28e1699fbae587 428 Pfam PF13183 4Fe-4S dicluster domain 21 88 5.6E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1805 a7ce9811a906f9665a28e1699fbae587 428 Gene3D G3DSA:3.30.70.20 20 88 3.4E-7 T 14-10-2018 Theos_1805 a7ce9811a906f9665a28e1699fbae587 428 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1805 a7ce9811a906f9665a28e1699fbae587 428 PIRSF PIRSF000139 8 416 1.1E-127 T 14-10-2018 Theos_1805 a7ce9811a906f9665a28e1699fbae587 428 Pfam PF02754 Cysteine-rich domain 309 393 2.0E-19 T 14-10-2018 IPR004017 Cysteine-rich domain Theos_1805 a7ce9811a906f9665a28e1699fbae587 428 Pfam PF02754 Cysteine-rich domain 184 260 4.2E-13 T 14-10-2018 IPR004017 Cysteine-rich domain Theos_1805 a7ce9811a906f9665a28e1699fbae587 428 SUPERFAMILY SSF46548 15 98 7.85E-20 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 SUPERFAMILY SSF51246 327 444 9.42E-43 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 317 1.1E-77 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 282 289 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 Gene3D G3DSA:3.30.470.130 1 445 5.3E-196 T 14-10-2018 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 442 8.9E-208 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 Pfam PF02785 Biotin carboxylase C-terminal domain 332 440 5.8E-40 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 SUPERFAMILY SSF52440 1 112 2.3E-45 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 SUPERFAMILY SSF56059 82 344 2.3E-75 T 14-10-2018 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 SMART SM00878 332 440 4.3E-66 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 SMART SM01209 113 288 0.0058 T 14-10-2018 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 151 165 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Theos_1487 fd0b6b24a2165d0b8413ea3d37513b0f 445 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 5.8E-42 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Theos_1068 6530aca26f56a303b9da25d841123f1c 291 Pfam PF01882 Protein of unknown function DUF58 36 119 2.6E-20 T 14-10-2018 IPR002881 Domain of unknown function DUF58 Theos_1181 a820e5e17adc96bc3dec5a94033c34a2 255 Gene3D G3DSA:3.20.20.70 1 253 6.0E-90 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1181 a820e5e17adc96bc3dec5a94033c34a2 255 Pfam PF00218 Indole-3-glycerol phosphate synthase 31 249 3.7E-65 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 Theos_1181 a820e5e17adc96bc3dec5a94033c34a2 255 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 48 65 - T 14-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 Theos_1181 a820e5e17adc96bc3dec5a94033c34a2 255 SUPERFAMILY SSF51366 6 252 5.34E-70 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Theos_0278 47b4fa65a6b5a7b3e5b6da5e0c8119cf 206 Gene3D G3DSA:3.40.1370.10 1 206 9.3E-72 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Theos_0278 47b4fa65a6b5a7b3e5b6da5e0c8119cf 206 SUPERFAMILY SSF52166 18 202 1.7E-62 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Theos_0278 47b4fa65a6b5a7b3e5b6da5e0c8119cf 206 Pfam PF00573 Ribosomal protein L4/L1 family 22 200 3.8E-56 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 Theos_0278 47b4fa65a6b5a7b3e5b6da5e0c8119cf 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 22 199 6.5E-63 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0278 47b4fa65a6b5a7b3e5b6da5e0c8119cf 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 203 28.416 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1949 5f7b091e8187b311860bb6fa124ed9f6 60 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 8 36 - T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Theos_1949 5f7b091e8187b311860bb6fa124ed9f6 60 Gene3D G3DSA:1.20.5.1030 1 60 5.1E-25 T 14-10-2018 IPR038379 SecE superfamily Theos_1949 5f7b091e8187b311860bb6fa124ed9f6 60 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 7 59 2.6E-16 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Theos_1949 5f7b091e8187b311860bb6fa124ed9f6 60 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 5 59 3.7E-18 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 Theos_1949 5f7b091e8187b311860bb6fa124ed9f6 60 Hamap MF_00422 Protein translocase subunit SecE [secE]. 3 58 12.391 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 Gene3D G3DSA:3.30.70.240 380 466 9.7E-111 T 14-10-2018 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 40 55 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 Gene3D G3DSA:2.40.50.250 467 583 9.7E-111 T 14-10-2018 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 SUPERFAMILY SSF50447 147 291 1.85E-27 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 SUPERFAMILY SSF52540 3 193 2.39E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 Gene3D G3DSA:3.40.50.300 1 192 7.2E-61 T 14-10-2018 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 Gene3D G3DSA:2.40.30.10 193 291 8.8E-31 T 14-10-2018 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 SMART SM00838 384 468 0.0028 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 Gene3D G3DSA:3.30.70.870 298 574 9.7E-111 T 14-10-2018 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 583 4.3E-252 T 14-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 132 1.7E-22 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 PRINTS PR00315 GTP-binding elongation factor signature 5 18 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 PRINTS PR00315 GTP-binding elongation factor signature 83 94 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 PRINTS PR00315 GTP-binding elongation factor signature 47 55 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 PRINTS PR00315 GTP-binding elongation factor signature 119 128 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 PRINTS PR00315 GTP-binding elongation factor signature 67 77 2.2E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 Pfam PF00679 Elongation factor G C-terminus 384 461 3.6E-17 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 SUPERFAMILY SSF54980 294 378 2.63E-12 T 14-10-2018 IPR035647 EF-G domain III/V-like Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 Pfam PF00009 Elongation factor Tu GTP binding domain 2 189 3.2E-50 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 Pfam PF03144 Elongation factor Tu domain 2 212 280 2.0E-11 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Theos_0155 5c6be6e690506e5838ac8d391b4411c8 587 SUPERFAMILY SSF54980 385 497 7.19E-24 T 14-10-2018 IPR035647 EF-G domain III/V-like Theos_0816 bb4f953d006cd4daed6efb798c230e54 648 Gene3D G3DSA:1.20.1460.20 41 267 4.7E-96 T 14-10-2018 Theos_0816 bb4f953d006cd4daed6efb798c230e54 648 Gene3D G3DSA:3.30.70.2170 1 290 4.7E-96 T 14-10-2018 Theos_0816 bb4f953d006cd4daed6efb798c230e54 648 Pfam PF01496 V-type ATPase 116kDa subunit family 227 428 3.7E-11 T 14-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0816 bb4f953d006cd4daed6efb798c230e54 648 Gene3D G3DSA:3.30.70.2750 127 199 4.7E-96 T 14-10-2018 Theos_0053 ecd2e38dcd9a8b09af3673ab62c4b377 519 SUPERFAMILY SSF51905 1 508 1.79E-71 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0053 ecd2e38dcd9a8b09af3673ab62c4b377 519 Gene3D G3DSA:3.50.50.60 1 87 5.3E-20 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0053 ecd2e38dcd9a8b09af3673ab62c4b377 519 Gene3D G3DSA:3.50.50.60 212 309 2.1E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0053 ecd2e38dcd9a8b09af3673ab62c4b377 519 Pfam PF01593 Flavin containing amine oxidoreductase 11 289 2.3E-24 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 Theos_0053 ecd2e38dcd9a8b09af3673ab62c4b377 519 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 3 509 1.9E-160 T 14-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 Theos_2121 c3642e8be3fbdb6c15c04ed48cf8096d 147 Gene3D G3DSA:3.40.5.10 1 59 5.7E-27 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2121 c3642e8be3fbdb6c15c04ed48cf8096d 147 SUPERFAMILY SSF55658 1 56 1.6E-18 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal Theos_2121 c3642e8be3fbdb6c15c04ed48cf8096d 147 Gene3D G3DSA:3.10.430.100 60 147 5.1E-32 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily Theos_2121 c3642e8be3fbdb6c15c04ed48cf8096d 147 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 25.72 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_2121 c3642e8be3fbdb6c15c04ed48cf8096d 147 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 2.4E-23 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2121 c3642e8be3fbdb6c15c04ed48cf8096d 147 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 145 1.1E-24 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal Theos_2121 c3642e8be3fbdb6c15c04ed48cf8096d 147 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_2121 c3642e8be3fbdb6c15c04ed48cf8096d 147 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 2.8E-42 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_2121 c3642e8be3fbdb6c15c04ed48cf8096d 147 SUPERFAMILY SSF55653 57 145 3.14E-24 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily Theos_1236 3e9b75f62938ae535def5380b40c61ea 155 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 23 1.4E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1236 3e9b75f62938ae535def5380b40c61ea 155 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1236 3e9b75f62938ae535def5380b40c61ea 155 Pfam PF12019 Type II transport protein GspH 38 152 8.2E-13 T 14-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 Theos_1236 3e9b75f62938ae535def5380b40c61ea 155 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 25 2.6E-7 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1236 3e9b75f62938ae535def5380b40c61ea 155 SUPERFAMILY SSF54523 5 144 1.18E-10 T 14-10-2018 Theos_0596 2eae7aede151f8dfd01921557ecc3075 85 Pfam PF13937 Domain of unknown function (DUF4212) 7 84 9.9E-34 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted Theos_0596 2eae7aede151f8dfd01921557ecc3075 85 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 8 85 3.4E-33 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 Gene3D G3DSA:3.40.50.1980 219 334 1.5E-111 T 14-10-2018 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 215 247 - T 14-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 412 38.933 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 PIRSF PIRSF000099 2 412 3.1E-146 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 27 411 3.7E-142 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 SUPERFAMILY SSF53720 25 411 1.41E-73 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 Pfam PF00815 Histidinol dehydrogenase 21 411 3.5E-145 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 Gene3D G3DSA:3.40.50.1980 26 218 1.5E-111 T 14-10-2018 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 PRINTS PR00083 Histidinol dehydrogenase signature 346 364 6.1E-78 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 PRINTS PR00083 Histidinol dehydrogenase signature 237 256 6.1E-78 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 PRINTS PR00083 Histidinol dehydrogenase signature 125 151 6.1E-78 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 PRINTS PR00083 Histidinol dehydrogenase signature 156 182 6.1E-78 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 PRINTS PR00083 Histidinol dehydrogenase signature 215 236 6.1E-78 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 PRINTS PR00083 Histidinol dehydrogenase signature 27 51 6.1E-78 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 PRINTS PR00083 Histidinol dehydrogenase signature 186 211 6.1E-78 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_1430 315a464eec9dd6a33d0a41228cb75583 412 PRINTS PR00083 Histidinol dehydrogenase signature 305 330 6.1E-78 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 85 3.0E-26 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 Gene3D G3DSA:2.40.50.100 20 85 1.4E-32 T 14-10-2018 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 77 3.8E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 Pfam PF01016 Ribosomal L27 protein 2 81 5.9E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 SUPERFAMILY SSF110324 2 82 1.01E-33 T 14-10-2018 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 28.625 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 6.2E-37 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 6.2E-37 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0255 5877cf7cf9d3a948e6a44d112873f867 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 6.2E-37 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 PRINTS PR00379 Intein signature 357 369 9.2E-6 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 PRINTS PR00379 Intein signature 159 172 9.2E-6 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 PRINTS PR00379 Intein signature 246 258 9.2E-6 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 PRINTS PR00379 Intein signature 400 415 9.2E-6 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 Pfam PF14890 Intein splicing domain 105 578 3.6E-10 T 14-10-2018 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 SUPERFAMILY SSF51294 97 580 3.01E-29 T 14-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 559 581 2.0E-5 T 14-10-2018 IPR030934 Intein C-terminal splicing region Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 Pfam PF01139 tRNA-splicing ligase RtcB 45 959 1.5E-154 T 14-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 Gene3D G3DSA:3.90.1860.10 1 117 1.3E-31 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 Gene3D G3DSA:3.90.1860.10 560 959 7.0E-143 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 SUPERFAMILY SSF103365 3 98 1.11E-23 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 98 172 7.0E-8 T 14-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 SMART SM00306 96 192 1.1E-14 T 14-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 SUPERFAMILY SSF103365 580 959 4.18E-130 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 45 74 - T 14-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 SMART SM00305 539 586 2.1E-9 T 14-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Theos_1904 7f1376c079e31dae2a0a2c032a1a7191 959 Gene3D G3DSA:3.10.28.10 244 434 2.1E-10 T 14-10-2018 IPR027434 Homing endonuclease Theos_0398 6ae343d59cc4a126ba1f99ad1cd7f939 622 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 104 478 3.8E-53 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain Theos_0398 6ae343d59cc4a126ba1f99ad1cd7f939 622 Gene3D G3DSA:3.40.190.10 21 610 1.8E-300 T 14-10-2018 Theos_0398 6ae343d59cc4a126ba1f99ad1cd7f939 622 PIRSF PIRSF002741 214 601 4.1E-46 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Theos_0398 6ae343d59cc4a126ba1f99ad1cd7f939 622 PIRSF PIRSF002741 18 192 4.9E-8 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Theos_0398 6ae343d59cc4a126ba1f99ad1cd7f939 622 Gene3D G3DSA:3.10.105.10 327 574 1.8E-300 T 14-10-2018 Theos_0398 6ae343d59cc4a126ba1f99ad1cd7f939 622 SUPERFAMILY SSF53850 21 601 2.17E-81 T 14-10-2018 Theos_0398 6ae343d59cc4a126ba1f99ad1cd7f939 622 Gene3D G3DSA:3.90.76.10 65 181 1.8E-300 T 14-10-2018 Theos_2092 99a97921514bb06900d37c777e89769f 323 Gene3D G3DSA:3.20.20.70 84 301 3.6E-20 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_2092 99a97921514bb06900d37c777e89769f 323 TIGRFAM TIGR00510 lipA: lipoyl synthase 36 321 3.5E-118 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Theos_2092 99a97921514bb06900d37c777e89769f 323 PIRSF PIRSF005963 8 323 3.5E-143 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Theos_2092 99a97921514bb06900d37c777e89769f 323 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 19 74 2.5E-9 T 14-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Theos_2092 99a97921514bb06900d37c777e89769f 323 SMART SM00729 85 292 7.1E-14 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_2092 99a97921514bb06900d37c777e89769f 323 SUPERFAMILY SSF102114 52 315 3.53E-63 T 14-10-2018 Theos_2092 99a97921514bb06900d37c777e89769f 323 Hamap MF_00206 Lipoyl synthase [lipA]. 38 323 142.557 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Theos_2092 99a97921514bb06900d37c777e89769f 323 Pfam PF04055 Radical SAM superfamily 92 253 2.6E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_2549 a007cfdf5876addd36dcf9e8c48711fe 810 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 639 645 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Theos_2549 a007cfdf5876addd36dcf9e8c48711fe 810 Pfam PF07669 Eco57I restriction-modification methylase 636 753 1.2E-6 T 14-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 Theos_2549 a007cfdf5876addd36dcf9e8c48711fe 810 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 366 382 6.1E-16 T 14-10-2018 Theos_2549 a007cfdf5876addd36dcf9e8c48711fe 810 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 425 439 6.1E-16 T 14-10-2018 Theos_2549 a007cfdf5876addd36dcf9e8c48711fe 810 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 695 719 6.1E-16 T 14-10-2018 Theos_2549 a007cfdf5876addd36dcf9e8c48711fe 810 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 636 648 6.1E-16 T 14-10-2018 Theos_2549 a007cfdf5876addd36dcf9e8c48711fe 810 SUPERFAMILY SSF53335 205 798 3.63E-43 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0496 02c0d74db1130f58fce684d72a59b2b5 97 Pfam PF00216 Bacterial DNA-binding protein 7 96 9.1E-35 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Theos_0496 02c0d74db1130f58fce684d72a59b2b5 97 SMART SM00411 7 96 4.8E-43 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Theos_0496 02c0d74db1130f58fce684d72a59b2b5 97 Gene3D G3DSA:4.10.520.10 2 97 5.4E-39 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Theos_0496 02c0d74db1130f58fce684d72a59b2b5 97 PRINTS PR01727 Prokaryotic integration host factor signature 46 61 4.0E-15 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Theos_0496 02c0d74db1130f58fce684d72a59b2b5 97 PRINTS PR01727 Prokaryotic integration host factor signature 64 77 4.0E-15 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Theos_0496 02c0d74db1130f58fce684d72a59b2b5 97 PRINTS PR01727 Prokaryotic integration host factor signature 80 94 4.0E-15 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Theos_0496 02c0d74db1130f58fce684d72a59b2b5 97 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 52 71 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Theos_0496 02c0d74db1130f58fce684d72a59b2b5 97 SUPERFAMILY SSF47729 7 96 4.86E-31 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Theos_0825 aa99a3d3d58e51d73f3496f6a65ba45c 244 Gene3D G3DSA:3.30.70.1900 106 237 1.0E-36 T 14-10-2018 Theos_0825 aa99a3d3d58e51d73f3496f6a65ba45c 244 Gene3D G3DSA:3.30.70.1890 1 105 3.2E-47 T 14-10-2018 Theos_0825 aa99a3d3d58e51d73f3496f6a65ba45c 244 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 120 234 9.7E-20 T 14-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 Gene3D G3DSA:3.30.450.90 479 611 3.7E-39 T 14-10-2018 Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 SUPERFAMILY SSF160246 165 299 2.88E-23 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 Pfam PF00437 Type II/IV secretion system protein 515 778 4.1E-75 T 14-10-2018 IPR001482 Type II/IV secretion system protein Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 SUPERFAMILY SSF160246 8 147 1.7E-32 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 SUPERFAMILY SSF160246 331 476 2.22E-34 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 SUPERFAMILY SSF52540 503 884 7.31E-97 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 369 479 7.9E-21 T 14-10-2018 IPR007831 General secretory system II, protein E, N-terminal Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 172 303 3.0E-11 T 14-10-2018 IPR007831 General secretory system II, protein E, N-terminal Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 44 149 8.8E-18 T 14-10-2018 IPR007831 General secretory system II, protein E, N-terminal Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 Gene3D G3DSA:3.40.50.300 613 888 6.2E-125 T 14-10-2018 Theos_1970 9544286bdb47c182dbe533cc60821cd2 888 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 706 720 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Theos_2063 9dae6861974a39e035fe9d3c62d8871f 166 SUPERFAMILY SSF52833 24 158 1.38E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_2063 9dae6861974a39e035fe9d3c62d8871f 166 Gene3D G3DSA:3.40.30.10 22 162 4.7E-39 T 14-10-2018 Theos_2063 9dae6861974a39e035fe9d3c62d8871f 166 Pfam PF00578 AhpC/TSA family 28 143 1.2E-15 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Theos_1958 5346d7b3099462436d96b9ae30185594 196 SUPERFAMILY SSF52499 12 193 1.23E-62 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Theos_1958 5346d7b3099462436d96b9ae30185594 196 Gene3D G3DSA:3.40.50.850 9 195 8.1E-62 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Theos_1958 5346d7b3099462436d96b9ae30185594 196 Pfam PF00857 Isochorismatase family 20 189 5.1E-44 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 Theos_0522 635d966fcc893ff4ec1870257e795bbb 162 SUPERFAMILY SSF89562 1 154 1.44E-43 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily Theos_0522 635d966fcc893ff4ec1870257e795bbb 162 Pfam PF03737 Aldolase/RraA 5 149 2.3E-38 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein Theos_0522 635d966fcc893ff4ec1870257e795bbb 162 Gene3D G3DSA:3.50.30.40 1 162 5.1E-54 T 14-10-2018 Theos_0522 635d966fcc893ff4ec1870257e795bbb 162 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 150 6.2E-49 T 14-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 Theos_1098 23b5adfef207de67c66bf9194dc569f5 256 PIRSF PIRSF000401 42 254 3.1E-54 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 Theos_1098 23b5adfef207de67c66bf9194dc569f5 256 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 254 28.492 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 Theos_1098 23b5adfef207de67c66bf9194dc569f5 256 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 50 249 4.8E-54 T 14-10-2018 Theos_1098 23b5adfef207de67c66bf9194dc569f5 256 SUPERFAMILY SSF53335 46 249 7.02E-48 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1098 23b5adfef207de67c66bf9194dc569f5 256 Gene3D G3DSA:3.30.70.1170 1 59 9.6E-30 T 14-10-2018 Theos_1098 23b5adfef207de67c66bf9194dc569f5 256 Gene3D G3DSA:3.40.50.150 63 252 9.7E-59 T 14-10-2018 Theos_2356 1af6a42a2bc2bc5d04596ea5d79efd3e 419 SUPERFAMILY SSF75011 58 394 8.37E-5 T 14-10-2018 Theos_2356 1af6a42a2bc2bc5d04596ea5d79efd3e 419 SUPERFAMILY SSF101898 146 262 5.75E-5 T 14-10-2018 Theos_2356 1af6a42a2bc2bc5d04596ea5d79efd3e 419 Pfam PF13449 Esterase-like activity of phytase 61 395 1.7E-38 T 14-10-2018 IPR027372 Phytase-like domain Theos_1764 f1e7a077a5d6e501458f328929cb1a01 380 Gene3D G3DSA:3.40.640.10 21 258 4.0E-135 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_1764 f1e7a077a5d6e501458f328929cb1a01 380 SUPERFAMILY SSF53383 8 378 3.16E-102 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_1764 f1e7a077a5d6e501458f328929cb1a01 380 Gene3D G3DSA:3.90.1150.10 10 374 4.0E-135 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_1764 f1e7a077a5d6e501458f328929cb1a01 380 PIRSF PIRSF005572 7 380 5.2E-120 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Theos_1764 f1e7a077a5d6e501458f328929cb1a01 380 Pfam PF00266 Aminotransferase class-V 10 365 4.8E-72 T 14-10-2018 IPR000192 Aminotransferase class V domain Theos_1284 da225ff125d248b61d6888d3e15e7038 402 Gene3D G3DSA:3.30.830.10 2 205 5.4E-29 T 14-10-2018 Theos_1284 da225ff125d248b61d6888d3e15e7038 402 Gene3D G3DSA:3.30.830.10 215 402 4.1E-43 T 14-10-2018 Theos_1284 da225ff125d248b61d6888d3e15e7038 402 Pfam PF05193 Peptidase M16 inactive domain 163 329 7.1E-23 T 14-10-2018 IPR007863 Peptidase M16, C-terminal Theos_1284 da225ff125d248b61d6888d3e15e7038 402 SUPERFAMILY SSF63411 4 201 6.75E-33 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Theos_1284 da225ff125d248b61d6888d3e15e7038 402 SUPERFAMILY SSF63411 219 399 2.67E-36 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Theos_2203 d08abc83ec9f1d28cb5916eceabba317 267 SUPERFAMILY SSF109709 105 214 5.75E-36 T 14-10-2018 Theos_2203 d08abc83ec9f1d28cb5916eceabba317 267 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 21 187 2.1E-56 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 Theos_2203 d08abc83ec9f1d28cb5916eceabba317 267 Pfam PF02195 ParB-like nuclease domain 26 112 5.1E-27 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Theos_2203 d08abc83ec9f1d28cb5916eceabba317 267 Gene3D G3DSA:3.90.1530.30 37 99 3.8E-30 T 14-10-2018 Theos_2203 d08abc83ec9f1d28cb5916eceabba317 267 Gene3D G3DSA:1.10.10.2830 100 212 1.7E-45 T 14-10-2018 Theos_2203 d08abc83ec9f1d28cb5916eceabba317 267 SUPERFAMILY SSF110849 24 115 1.02E-30 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Theos_2203 d08abc83ec9f1d28cb5916eceabba317 267 SMART SM00470 24 113 1.7E-38 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Theos_0781 07f5ef01553027827304c1c3e7cdc477 553 Pfam PF02660 Glycerol-3-phosphate acyltransferase 8 187 2.8E-28 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_0781 07f5ef01553027827304c1c3e7cdc477 553 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 363 482 2.4E-8 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Theos_0781 07f5ef01553027827304c1c3e7cdc477 553 SUPERFAMILY SSF51735 352 480 1.75E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0781 07f5ef01553027827304c1c3e7cdc477 553 Gene3D G3DSA:3.40.50.720 345 488 8.4E-16 T 14-10-2018 Theos_0781 07f5ef01553027827304c1c3e7cdc477 553 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 4 196 13.448 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_0781 07f5ef01553027827304c1c3e7cdc477 553 PIRSF PIRSF026478 1 553 0.0 T 14-10-2018 IPR021194 Uncharacterised protein family, dehydrogenase DR0790 type, predicted Theos_0781 07f5ef01553027827304c1c3e7cdc477 553 SMART SM01207 7 188 2.4E-27 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_1107 4a9df90eb04e8b507fae4aedcadde905 464 Pfam PF07728 AAA domain (dynein-related subfamily) 130 242 1.8E-4 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Theos_1107 4a9df90eb04e8b507fae4aedcadde905 464 SUPERFAMILY SSF52540 41 376 3.55E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1107 4a9df90eb04e8b507fae4aedcadde905 464 Gene3D G3DSA:3.40.50.300 39 249 1.5E-25 T 14-10-2018 Theos_2231 2dabd75ca80aeb054554d62a34381125 458 Gene3D G3DSA:3.40.309.10 230 458 5.4E-82 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Theos_2231 2dabd75ca80aeb054554d62a34381125 458 Gene3D G3DSA:3.40.605.10 4 229 1.5E-70 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_2231 2dabd75ca80aeb054554d62a34381125 458 SUPERFAMILY SSF53720 7 455 5.37E-148 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_2231 2dabd75ca80aeb054554d62a34381125 458 Pfam PF00171 Aldehyde dehydrogenase family 7 447 1.3E-148 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Theos_2231 2dabd75ca80aeb054554d62a34381125 458 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 226 233 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Theos_1411 f1af276bd3728b03de53da56f45e949f 213 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 192 2.6E-64 T 14-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 Theos_1411 f1af276bd3728b03de53da56f45e949f 213 Pfam PF03315 Serine dehydratase beta chain 5 71 3.3E-12 T 14-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 Theos_1411 f1af276bd3728b03de53da56f45e949f 213 Pfam PF01842 ACT domain 141 188 2.8E-8 T 14-10-2018 IPR002912 ACT domain Theos_1411 f1af276bd3728b03de53da56f45e949f 213 Gene3D G3DSA:3.30.1330.90 5 126 1.2E-18 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Theos_1411 f1af276bd3728b03de53da56f45e949f 213 SUPERFAMILY SSF55021 129 210 5.39E-14 T 14-10-2018 Theos_1411 f1af276bd3728b03de53da56f45e949f 213 Gene3D G3DSA:3.30.70.260 139 202 8.4E-14 T 14-10-2018 Theos_1411 f1af276bd3728b03de53da56f45e949f 213 SUPERFAMILY SSF143548 11 127 7.19E-30 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Theos_1411 f1af276bd3728b03de53da56f45e949f 213 PIRSF PIRSF036692 1 211 2.4E-76 T 14-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 Theos_0082 02c5e7195de6d7ec8a9c9842e497a8de 448 Gene3D G3DSA:3.30.70.2740 330 408 5.7E-10 T 14-10-2018 Theos_0082 02c5e7195de6d7ec8a9c9842e497a8de 448 Gene3D G3DSA:3.30.465.40 6 226 4.5E-70 T 14-10-2018 Theos_0082 02c5e7195de6d7ec8a9c9842e497a8de 448 Pfam PF01565 FAD binding domain 37 173 6.6E-37 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Theos_0082 02c5e7195de6d7ec8a9c9842e497a8de 448 SUPERFAMILY SSF56176 4 210 1.96E-65 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Theos_0082 02c5e7195de6d7ec8a9c9842e497a8de 448 SUPERFAMILY SSF55103 214 448 7.85E-61 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Theos_0082 02c5e7195de6d7ec8a9c9842e497a8de 448 Pfam PF02913 FAD linked oxidases, C-terminal domain 210 447 7.1E-55 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Theos_0082 02c5e7195de6d7ec8a9c9842e497a8de 448 Gene3D G3DSA:1.10.45.10 409 448 9.9E-14 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 254 392 4.0E-28 T 14-10-2018 IPR008136 CinA, C-terminal Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 Gene3D G3DSA:3.30.70.2860 174 247 8.4E-40 T 14-10-2018 Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 SMART SM00852 5 171 2.1E-32 T 14-10-2018 IPR001453 MoaB/Mog domain Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 SUPERFAMILY SSF53218 3 201 3.53E-33 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 394 123.51 T 14-10-2018 IPR008135 Competence-induced protein CinA Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 389 1.9E-80 T 14-10-2018 IPR008135 Competence-induced protein CinA Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 Pfam PF00994 Probable molybdopterin binding domain 6 168 8.5E-29 T 14-10-2018 IPR001453 MoaB/Mog domain Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 SUPERFAMILY SSF142433 242 392 6.41E-42 T 14-10-2018 IPR036653 CinA-like, C-terminal Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 Pfam PF02464 Competence-damaged protein 248 392 3.5E-44 T 14-10-2018 IPR008136 CinA, C-terminal Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 Gene3D G3DSA:3.40.980.10 1 172 6.1E-51 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 PIRSF PIRSF006728 1 394 2.0E-106 T 14-10-2018 IPR008135 Competence-induced protein CinA Theos_0178 8dbccbaa8a8ecebecba0b1912a022f17 394 Gene3D G3DSA:3.90.950.20 248 394 2.3E-55 T 14-10-2018 IPR036653 CinA-like, C-terminal Theos_0881 2ea5678b8e9da379bcee5c2023efa051 170 Gene3D G3DSA:3.40.1260.10 39 168 1.9E-21 T 14-10-2018 IPR027396 DsrEFH-like Theos_0881 2ea5678b8e9da379bcee5c2023efa051 170 SUPERFAMILY SSF75169 43 168 2.41E-21 T 14-10-2018 IPR027396 DsrEFH-like Theos_0881 2ea5678b8e9da379bcee5c2023efa051 170 Pfam PF02635 DsrE/DsrF-like family 43 168 5.4E-13 T 14-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein Theos_1514 cd8a086c00c6655fe3d4186f6bbc5541 222 SUPERFAMILY SSF52141 15 218 1.54E-48 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Theos_1514 cd8a086c00c6655fe3d4186f6bbc5541 222 Pfam PF03167 Uracil DNA glycosylase superfamily 47 212 4.0E-35 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Theos_1514 cd8a086c00c6655fe3d4186f6bbc5541 222 SMART SM00987 47 213 6.8E-29 T 14-10-2018 Theos_1514 cd8a086c00c6655fe3d4186f6bbc5541 222 Gene3D G3DSA:3.40.470.10 3 222 2.3E-73 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Theos_1514 cd8a086c00c6655fe3d4186f6bbc5541 222 SMART SM00986 47 213 6.8E-29 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 328 38.467 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 327 2.0E-91 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 68 87 7.7E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 7.7E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 195 205 7.7E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 143 164 7.7E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 Gene3D G3DSA:1.10.240.10 189 295 8.3E-134 T 14-10-2018 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 Gene3D G3DSA:3.40.50.620 3 327 8.3E-134 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 SUPERFAMILY SSF52374 1 327 1.3E-89 T 14-10-2018 Theos_1247 d8d54851b60b4f907a429bd1abe7168e 337 Pfam PF00579 tRNA synthetases class I (W and Y) 3 274 3.0E-70 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Theos_2449 7b2e997d5148c4c502540df22f852f24 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.4E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2449 7b2e997d5148c4c502540df22f852f24 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.4E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2449 7b2e997d5148c4c502540df22f852f24 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 6.4E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2449 7b2e997d5148c4c502540df22f852f24 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 250 1.2E-66 T 14-10-2018 Theos_2449 7b2e997d5148c4c502540df22f852f24 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_2449 7b2e997d5148c4c502540df22f852f24 260 Gene3D G3DSA:3.40.50.720 3 255 4.5E-76 T 14-10-2018 Theos_2449 7b2e997d5148c4c502540df22f852f24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2449 7b2e997d5148c4c502540df22f852f24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2449 7b2e997d5148c4c502540df22f852f24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2449 7b2e997d5148c4c502540df22f852f24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2449 7b2e997d5148c4c502540df22f852f24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2449 7b2e997d5148c4c502540df22f852f24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2449 7b2e997d5148c4c502540df22f852f24 260 SUPERFAMILY SSF51735 12 251 1.45E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1182 0094ba0203ee0c7679a39d5f83f0bad3 232 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 229 2.7E-69 T 14-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 Theos_1182 0094ba0203ee0c7679a39d5f83f0bad3 232 Gene3D G3DSA:3.20.20.70 1 232 1.6E-80 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1182 0094ba0203ee0c7679a39d5f83f0bad3 232 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 232 31.424 T 14-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 Theos_1182 0094ba0203ee0c7679a39d5f83f0bad3 232 Pfam PF00977 Histidine biosynthesis protein 3 226 3.5E-66 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Theos_1182 0094ba0203ee0c7679a39d5f83f0bad3 232 SUPERFAMILY SSF51366 1 230 1.18E-61 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Theos_0485 2bef296913c39023cfef041434639df5 202 Gene3D G3DSA:2.60.120.10 1 117 9.2E-24 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_0485 2bef296913c39023cfef041434639df5 202 SMART SM00419 139 187 2.2E-9 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_0485 2bef296913c39023cfef041434639df5 202 Gene3D G3DSA:1.10.10.10 118 197 4.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0485 2bef296913c39023cfef041434639df5 202 Pfam PF13545 Crp-like helix-turn-helix domain 122 194 6.4E-16 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_0485 2bef296913c39023cfef041434639df5 202 SUPERFAMILY SSF46785 120 196 1.18E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0485 2bef296913c39023cfef041434639df5 202 Pfam PF00027 Cyclic nucleotide-binding domain 8 87 3.2E-12 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Theos_0485 2bef296913c39023cfef041434639df5 202 SUPERFAMILY SSF51206 7 104 2.36E-19 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Theos_1158 9c27bf9051a36fb19bbe0f17b4a51128 551 Pfam PF01642 Methylmalonyl-CoA mutase 27 543 4.2E-226 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Theos_1158 9c27bf9051a36fb19bbe0f17b4a51128 551 SUPERFAMILY SSF51703 4 545 1.2E-214 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Theos_1158 9c27bf9051a36fb19bbe0f17b4a51128 551 Gene3D G3DSA:3.20.20.240 1 551 2.3E-249 T 14-10-2018 Theos_1158 9c27bf9051a36fb19bbe0f17b4a51128 551 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 26 549 5.0E-232 T 14-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Theos_1822 468d028386d7c33970635fed93308a47 444 Gene3D G3DSA:3.60.110.10 245 414 6.0E-14 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Theos_1822 468d028386d7c33970635fed93308a47 444 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 252 387 9.1E-41 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Theos_1822 468d028386d7c33970635fed93308a47 444 SUPERFAMILY SSF56317 176 419 9.55E-37 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Theos_1822 468d028386d7c33970635fed93308a47 444 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 1 425 18.047 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Theos_1822 468d028386d7c33970635fed93308a47 444 Pfam PF00795 Carbon-nitrogen hydrolase 253 402 2.9E-20 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 408 418 - T 14-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 SUPERFAMILY SSF53613 207 467 2.81E-63 T 14-10-2018 IPR029056 Ribokinase-like Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 SUPERFAMILY SSF64153 1 229 2.35E-54 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 Pfam PF03853 YjeF-related protein N-terminus 26 173 2.3E-32 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 Pfam PF01256 Carbohydrate kinase 242 465 8.8E-45 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 207 472 21.756 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 209 466 1.2E-51 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 Gene3D G3DSA:3.40.1190.20 202 469 2.0E-73 T 14-10-2018 IPR029056 Ribokinase-like Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 Gene3D G3DSA:3.40.50.10260 2 201 3.1E-48 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 193 21.577 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 PIRSF PIRSF017184 1 474 5.1E-106 T 14-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 Theos_1596 e7a0f9ccbb10014e21f8d9059e67685f 482 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 4 194 9.3E-34 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Theos_2404 f2c71bce17a8bd2c1a786e8e43b72b46 344 Gene3D G3DSA:1.10.1530.10 1 73 9.0E-21 T 14-10-2018 Theos_2404 f2c71bce17a8bd2c1a786e8e43b72b46 344 SUPERFAMILY SSF89733 1 338 5.89E-111 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 Theos_2404 f2c71bce17a8bd2c1a786e8e43b72b46 344 Pfam PF02615 Malate/L-lactate dehydrogenase 5 330 1.2E-115 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 Theos_2404 f2c71bce17a8bd2c1a786e8e43b72b46 344 Gene3D G3DSA:1.10.1530.10 300 344 6.6E-8 T 14-10-2018 Theos_2404 f2c71bce17a8bd2c1a786e8e43b72b46 344 Gene3D G3DSA:3.30.1370.60 74 299 1.2E-96 T 14-10-2018 Theos_2132 3d358d43d03f89364eafd73802487805 497 Pfam PF01078 Magnesium chelatase, subunit ChlI 188 389 3.5E-95 T 14-10-2018 IPR000523 Magnesium chelatase ChlI domain Theos_2132 3d358d43d03f89364eafd73802487805 497 Gene3D G3DSA:3.30.230.10 15 167 1.4E-6 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Theos_2132 3d358d43d03f89364eafd73802487805 497 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 399 491 7.0E-29 T 14-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain Theos_2132 3d358d43d03f89364eafd73802487805 497 SMART SM00382 208 389 4.3E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2132 3d358d43d03f89364eafd73802487805 497 Gene3D G3DSA:3.40.50.300 189 496 1.2E-62 T 14-10-2018 Theos_2132 3d358d43d03f89364eafd73802487805 497 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 140 5.5E-41 T 14-10-2018 Theos_2132 3d358d43d03f89364eafd73802487805 497 SUPERFAMILY SSF52540 188 492 1.07E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2132 3d358d43d03f89364eafd73802487805 497 SUPERFAMILY SSF54211 7 168 4.55E-34 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_2132 3d358d43d03f89364eafd73802487805 497 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 491 3.5E-174 T 14-10-2018 IPR004482 Mg chelatase-related protein Theos_2132 3d358d43d03f89364eafd73802487805 497 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 314 327 1.9E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Theos_2132 3d358d43d03f89364eafd73802487805 497 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 286 300 1.9E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Theos_2132 3d358d43d03f89364eafd73802487805 497 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 207 222 1.9E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Theos_2132 3d358d43d03f89364eafd73802487805 497 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 338 350 1.9E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Theos_2163 dc3c6b24dcb005a79b34b59e0f7b45b2 280 SUPERFAMILY SSF161098 8 280 2.62E-71 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2163 dc3c6b24dcb005a79b34b59e0f7b45b2 280 Gene3D G3DSA:1.10.3720.10 4 271 1.5E-63 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2163 dc3c6b24dcb005a79b34b59e0f7b45b2 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 272 1.3E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2300 4c3a0ff7c4addfbf5c5d85505223da70 215 Pfam PF13241 Putative NAD(P)-binding 6 114 6.5E-14 T 14-10-2018 Theos_2300 4c3a0ff7c4addfbf5c5d85505223da70 215 Gene3D G3DSA:3.30.160.110 112 147 5.7E-11 T 14-10-2018 Theos_2300 4c3a0ff7c4addfbf5c5d85505223da70 215 SUPERFAMILY SSF51735 1 108 1.71E-8 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2300 4c3a0ff7c4addfbf5c5d85505223da70 215 SUPERFAMILY SSF75615 113 187 2.35E-18 T 14-10-2018 Theos_2300 4c3a0ff7c4addfbf5c5d85505223da70 215 Pfam PF14824 Sirohaem biosynthesis protein central 118 143 2.9E-7 T 14-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Theos_2300 4c3a0ff7c4addfbf5c5d85505223da70 215 Gene3D G3DSA:3.40.50.720 1 110 9.9E-16 T 14-10-2018 Theos_2300 4c3a0ff7c4addfbf5c5d85505223da70 215 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 182 1.0E-33 T 14-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Theos_1660 ba89def735ecca255b0f3ebed9c17f28 131 SUPERFAMILY SSF81343 17 126 1.35E-24 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1660 ba89def735ecca255b0f3ebed9c17f28 131 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 18 115 5.4E-16 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1660 ba89def735ecca255b0f3ebed9c17f28 131 Gene3D G3DSA:1.20.1300.10 12 125 8.5E-22 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_0236 7a6f1fa4fb4be867498f732928a25354 181 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 180 1.1E-48 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 Theos_0236 7a6f1fa4fb4be867498f732928a25354 181 Gene3D G3DSA:2.70.40.10 1 154 1.1E-49 T 14-10-2018 IPR036157 dUTPase-like superfamily Theos_0236 7a6f1fa4fb4be867498f732928a25354 181 Hamap MF_00146 dCTP deaminase [dcd]. 1 181 28.515 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 Theos_0236 7a6f1fa4fb4be867498f732928a25354 181 SUPERFAMILY SSF51283 1 180 1.09E-50 T 14-10-2018 IPR036157 dUTPase-like superfamily Theos_0236 7a6f1fa4fb4be867498f732928a25354 181 Pfam PF00692 dUTPase 73 177 1.8E-7 T 14-10-2018 IPR029054 dUTPase-like Theos_0863 d8a40bfeaad92f3c278810319436e002 405 Pfam PF01551 Peptidase family M23 312 388 6.9E-12 T 14-10-2018 IPR016047 Peptidase M23 Theos_0863 d8a40bfeaad92f3c278810319436e002 405 SUPERFAMILY SSF51261 221 401 1.26E-15 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_0863 d8a40bfeaad92f3c278810319436e002 405 Gene3D G3DSA:1.20.5.170 44 97 8.1E-7 T 14-10-2018 Theos_0863 d8a40bfeaad92f3c278810319436e002 405 Gene3D G3DSA:2.70.70.10 306 405 4.9E-14 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_0535 391ea6cc81ad44f45fdd9b7feda4a9cd 80 Pfam PF09360 Iron-binding zinc finger CDGSH type 8 54 1.1E-14 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 Theos_0535 391ea6cc81ad44f45fdd9b7feda4a9cd 80 SMART SM00704 26 59 9.9E-8 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 Theos_0535 391ea6cc81ad44f45fdd9b7feda4a9cd 80 Gene3D G3DSA:3.40.5.90 1 66 8.2E-17 T 14-10-2018 Theos_2178 610c958e11964454c93b614eba0d7f2d 68 SUPERFAMILY SSF50249 1 68 8.14E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_2178 610c958e11964454c93b614eba0d7f2d 68 PRINTS PR00050 Cold shock protein signature 39 57 9.0E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Theos_2178 610c958e11964454c93b614eba0d7f2d 68 PRINTS PR00050 Cold shock protein signature 24 33 9.0E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Theos_2178 610c958e11964454c93b614eba0d7f2d 68 PRINTS PR00050 Cold shock protein signature 4 19 9.0E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Theos_2178 610c958e11964454c93b614eba0d7f2d 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 67 9.0E-29 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Theos_2178 610c958e11964454c93b614eba0d7f2d 68 PIRSF PIRSF002599 1 68 3.3E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 Theos_2178 610c958e11964454c93b614eba0d7f2d 68 SMART SM00357 3 68 2.8E-30 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 Theos_2178 610c958e11964454c93b614eba0d7f2d 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 14-10-2018 IPR019844 Cold-shock conserved site Theos_2178 610c958e11964454c93b614eba0d7f2d 68 Gene3D G3DSA:2.40.50.140 1 68 1.6E-32 T 14-10-2018 Theos_1965 a17d9fddac0b14ef1716b6c23865a157 125 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 121 20.05 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Theos_1965 a17d9fddac0b14ef1716b6c23865a157 125 TIGRFAM TIGR00494 crcB: protein CrcB 5 118 3.2E-26 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Theos_1965 a17d9fddac0b14ef1716b6c23865a157 125 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 116 3.5E-24 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Theos_1920 20400752ee0e35909ebe56886d623f65 378 Pfam PF01478 Type IV leader peptidase family 104 340 5.9E-14 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 Theos_1920 20400752ee0e35909ebe56886d623f65 378 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 11 93 5.2E-32 T 14-10-2018 IPR010627 Peptidase A24A, N-terminal Theos_0809 9cb096fb51a659b216cdf3f41ce1e8a5 633 Pfam PF13193 AMP-binding enzyme C-terminal domain 514 592 1.0E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Theos_0809 9cb096fb51a659b216cdf3f41ce1e8a5 633 SUPERFAMILY SSF56801 17 623 3.79E-146 T 14-10-2018 Theos_0809 9cb096fb51a659b216cdf3f41ce1e8a5 633 Pfam PF00501 AMP-binding enzyme 84 505 2.2E-74 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_0809 9cb096fb51a659b216cdf3f41ce1e8a5 633 ProSitePatterns PS00455 Putative AMP-binding domain signature. 247 258 - T 14-10-2018 IPR020845 AMP-binding, conserved site Theos_0809 9cb096fb51a659b216cdf3f41ce1e8a5 633 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 27 79 5.0E-8 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Theos_0809 9cb096fb51a659b216cdf3f41ce1e8a5 633 Gene3D G3DSA:3.40.50.12780 71 499 2.9E-84 T 14-10-2018 Theos_0809 9cb096fb51a659b216cdf3f41ce1e8a5 633 Gene3D G3DSA:3.30.300.30 501 629 2.5E-26 T 14-10-2018 Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 SMART SM00861 349 520 4.8E-68 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 Gene3D G3DSA:3.40.50.970 1 327 1.8E-117 T 14-10-2018 Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 Pfam PF02780 Transketolase, C-terminal domain 533 643 3.6E-9 T 14-10-2018 IPR033248 Transketolase, C-terminal domain Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 SUPERFAMILY SSF52518 10 331 5.16E-108 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 SUPERFAMILY SSF52922 527 651 3.8E-43 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 10 336 1.8E-143 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 Pfam PF02779 Transketolase, pyrimidine binding domain 348 519 3.0E-45 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 Gene3D G3DSA:3.40.50.920 532 651 4.4E-43 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 SUPERFAMILY SSF52518 343 521 4.89E-67 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 Gene3D G3DSA:3.40.50.970 329 530 8.8E-79 T 14-10-2018 Theos_1745 d2091fb75a9d5d9dab4395c3968b82c2 651 TIGRFAM TIGR00232 tktlase_bact: transketolase 11 650 4.9E-262 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 Theos_2319 71331b1d60a66cd569949da950cef6fb 219 PIRSF PIRSF036427 1 219 8.5E-38 T 14-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 Theos_2319 71331b1d60a66cd569949da950cef6fb 219 Gene3D G3DSA:3.40.1010.10 1 123 5.0E-24 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Theos_2319 71331b1d60a66cd569949da950cef6fb 219 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 198 5.2E-31 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Theos_2319 71331b1d60a66cd569949da950cef6fb 219 SUPERFAMILY SSF53790 2 198 4.71E-27 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 Pfam PF02817 e3 binding domain 116 151 1.2E-14 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 180 406 2.7E-86 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 Pfam PF00364 Biotin-requiring enzyme 2 73 3.7E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 SUPERFAMILY SSF52777 167 405 1.42E-87 T 14-10-2018 Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 Gene3D G3DSA:2.40.50.100 1 80 1.8E-24 T 14-10-2018 Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 SUPERFAMILY SSF51230 2 93 3.93E-24 T 14-10-2018 IPR011053 Single hybrid motif Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 Gene3D G3DSA:4.10.320.10 114 155 6.5E-16 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 SUPERFAMILY SSF47005 110 154 2.09E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Theos_2160 3621d9f04dd3c91953741ff08f97a370 409 Gene3D G3DSA:3.30.559.10 164 408 5.3E-94 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Theos_2106 6714925ccf192379c01aae6cbb1dad0b 263 Gene3D G3DSA:3.40.50.150 9 252 1.1E-89 T 14-10-2018 Theos_2106 6714925ccf192379c01aae6cbb1dad0b 263 SUPERFAMILY SSF53335 7 241 1.02E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_2106 6714925ccf192379c01aae6cbb1dad0b 263 Gene3D G3DSA:1.10.8.900 147 248 1.1E-89 T 14-10-2018 Theos_2106 6714925ccf192379c01aae6cbb1dad0b 263 Pfam PF08241 Methyltransferase domain 44 137 5.2E-22 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Theos_0388 293d5ad6ae17a88b4c08df86d93ba584 257 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 172 182 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Theos_0388 293d5ad6ae17a88b4c08df86d93ba584 257 SUPERFAMILY SSF53681 110 242 3.76E-35 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Theos_0388 293d5ad6ae17a88b4c08df86d93ba584 257 Gene3D G3DSA:3.40.50.1860 97 198 4.6E-78 T 14-10-2018 Theos_0388 293d5ad6ae17a88b4c08df86d93ba584 257 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 206 1.4E-31 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Theos_0388 293d5ad6ae17a88b4c08df86d93ba584 257 SUPERFAMILY SSF53681 7 107 2.81E-35 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Theos_0388 293d5ad6ae17a88b4c08df86d93ba584 257 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 240 9.0E-62 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Theos_0388 293d5ad6ae17a88b4c08df86d93ba584 257 Gene3D G3DSA:3.40.50.1860 7 242 4.6E-78 T 14-10-2018 Theos_0388 293d5ad6ae17a88b4c08df86d93ba584 257 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 14-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Theos_0388 293d5ad6ae17a88b4c08df86d93ba584 257 Hamap MF_00258 Glutamate racemase [murI]. 6 246 34.257 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Theos_0911 4497fea406f31f85c71a960996c42c0a 108 SUPERFAMILY SSF101386 1 96 9.98E-22 T 14-10-2018 Theos_0911 4497fea406f31f85c71a960996c42c0a 108 Gene3D G3DSA:1.10.287.1080 1 100 1.7E-16 T 14-10-2018 Theos_0911 4497fea406f31f85c71a960996c42c0a 108 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 97 4.2E-14 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Theos_0911 4497fea406f31f85c71a960996c42c0a 108 PIRSF PIRSF006639 1 108 2.2E-38 T 14-10-2018 IPR011379 NTP Pyrophosphohydrolase MazG-related, GP37 Theos_0910 bff0f2385154fd609f17030b65940cd7 217 Pfam PF00578 AhpC/TSA family 12 139 3.4E-35 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Theos_0910 bff0f2385154fd609f17030b65940cd7 217 Hamap MF_00401 Peroxiredoxin. 9 216 42.394 T 14-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Theos_0910 bff0f2385154fd609f17030b65940cd7 217 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 161 191 2.2E-11 T 14-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Theos_0910 bff0f2385154fd609f17030b65940cd7 217 SUPERFAMILY SSF52833 7 195 5.38E-67 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0910 bff0f2385154fd609f17030b65940cd7 217 Gene3D G3DSA:3.40.30.10 3 197 7.4E-68 T 14-10-2018 Theos_0910 bff0f2385154fd609f17030b65940cd7 217 PIRSF PIRSF000239 4 215 7.6E-76 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 320 60.912 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 Pfam PF00814 Glycoprotease family 23 294 2.9E-90 T 14-10-2018 IPR000905 Gcp-like domain Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 Gene3D G3DSA:3.30.420.40 126 281 1.8E-107 T 14-10-2018 Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 ProSitePatterns PS01016 Glycoprotease family signature. 95 115 - T 14-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 Gene3D G3DSA:3.30.420.40 3 303 1.8E-107 T 14-10-2018 Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 300 1.5E-110 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 SUPERFAMILY SSF53067 3 298 2.81E-34 T 14-10-2018 Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 75 95 1.2E-46 T 14-10-2018 IPR017861 Kae1/TsaD family Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 128 140 1.2E-46 T 14-10-2018 IPR017861 Kae1/TsaD family Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 96 115 1.2E-46 T 14-10-2018 IPR017861 Kae1/TsaD family Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 255 264 1.2E-46 T 14-10-2018 IPR017861 Kae1/TsaD family Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.2E-46 T 14-10-2018 IPR017861 Kae1/TsaD family Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 151 172 1.2E-46 T 14-10-2018 IPR017861 Kae1/TsaD family Theos_1272 9afa0443663e634564f1c14e9b473cdb 323 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 294 1.2E-91 T 14-10-2018 IPR017861 Kae1/TsaD family Theos_1168 af2c17f8d2b822a06dc0fea66df470a2 143 Pfam PF02576 RimP N-terminal domain 8 76 8.8E-13 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal Theos_1168 af2c17f8d2b822a06dc0fea66df470a2 143 Gene3D G3DSA:3.30.300.70 2 75 4.9E-8 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily Theos_1168 af2c17f8d2b822a06dc0fea66df470a2 143 SUPERFAMILY SSF74942 79 127 3.66E-6 T 14-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily Theos_1168 af2c17f8d2b822a06dc0fea66df470a2 143 Pfam PF17384 RimP C-terminal SH3 domain 81 123 8.3E-8 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal Theos_1168 af2c17f8d2b822a06dc0fea66df470a2 143 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 3 131 14.447 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 Theos_1168 af2c17f8d2b822a06dc0fea66df470a2 143 SUPERFAMILY SSF75420 5 76 1.83E-11 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 234 1.6E-59 T 14-10-2018 Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 SUPERFAMILY SSF51735 1 235 2.38E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 Gene3D G3DSA:3.40.50.720 2 235 7.1E-75 T 14-10-2018 Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 9.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 9.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 9.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 9.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 9.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 3.2E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 3.2E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2405 024400929ba948ee4ec12844a3f7cb1e 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 3.2E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0518 4a0caeb09537c6eeac4eb8b2013693a5 224 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 103 187 1.0E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0518 4a0caeb09537c6eeac4eb8b2013693a5 224 SUPERFAMILY SSF46626 90 203 1.31E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_0518 4a0caeb09537c6eeac4eb8b2013693a5 224 Gene3D G3DSA:1.10.760.10 31 88 1.1E-7 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_0518 4a0caeb09537c6eeac4eb8b2013693a5 224 Gene3D G3DSA:1.10.760.10 104 224 3.5E-35 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_0518 4a0caeb09537c6eeac4eb8b2013693a5 224 Pfam PF09098 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding 32 97 6.4E-6 T 14-10-2018 IPR015182 Quinohemoprotein amine dehydrogenase, alpha subunit, haem binding domain Theos_0518 4a0caeb09537c6eeac4eb8b2013693a5 224 SUPERFAMILY SSF46626 30 99 1.28E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1129 fc40dc7e15da38bed8132a6e48af4425 265 SUPERFAMILY SSF56176 8 181 3.6E-29 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Theos_1129 fc40dc7e15da38bed8132a6e48af4425 265 Gene3D G3DSA:3.30.43.10 1 67 2.5E-26 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Theos_1129 fc40dc7e15da38bed8132a6e48af4425 265 SUPERFAMILY SSF56194 173 263 1.27E-25 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_1129 fc40dc7e15da38bed8132a6e48af4425 265 Gene3D G3DSA:3.90.78.10 189 265 1.7E-33 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_1129 fc40dc7e15da38bed8132a6e48af4425 265 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 8 256 3.3E-48 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_1129 fc40dc7e15da38bed8132a6e48af4425 265 Pfam PF01565 FAD binding domain 34 130 1.8E-9 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Theos_1129 fc40dc7e15da38bed8132a6e48af4425 265 Gene3D G3DSA:3.30.465.10 68 188 8.3E-42 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Theos_1129 fc40dc7e15da38bed8132a6e48af4425 265 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 265 63.818 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_1129 fc40dc7e15da38bed8132a6e48af4425 265 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 173 255 5.2E-22 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_1253 49870827880fd8feb59e78b945c5e3e5 177 SUPERFAMILY SSF52980 4 174 1.45E-17 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_1253 49870827880fd8feb59e78b945c5e3e5 177 Gene3D G3DSA:3.90.1570.10 1 177 7.3E-13 T 14-10-2018 Theos_1253 49870827880fd8feb59e78b945c5e3e5 177 Pfam PF05685 Putative restriction endonuclease 8 170 3.3E-29 T 14-10-2018 IPR008538 Domain of unknown function DUF820 Theos_0066 b0a9cac016a75f6ee5052a54f9fb3ef9 347 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 15 345 1.1E-105 T 14-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme Theos_0066 b0a9cac016a75f6ee5052a54f9fb3ef9 347 Gene3D G3DSA:3.20.20.70 67 295 1.3E-32 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0066 b0a9cac016a75f6ee5052a54f9fb3ef9 347 PIRSF PIRSF004869 2 322 2.2E-98 T 14-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted Theos_0066 b0a9cac016a75f6ee5052a54f9fb3ef9 347 Pfam PF04055 Radical SAM superfamily 83 239 2.6E-19 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_0066 b0a9cac016a75f6ee5052a54f9fb3ef9 347 SUPERFAMILY SSF102114 50 323 1.33E-32 T 14-10-2018 Theos_1353 1393d1ccd40e700ce8b804a1a061c9f0 109 SUPERFAMILY SSF54913 1 109 4.89E-15 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Theos_1353 1393d1ccd40e700ce8b804a1a061c9f0 109 Gene3D G3DSA:3.30.70.120 1 103 5.3E-39 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Theos_1353 1393d1ccd40e700ce8b804a1a061c9f0 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 5.1E-48 T 14-10-2018 IPR010375 Cyclic-di-AMP receptor Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 2 139 3.6E-62 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 4 140 30.48 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 SUPERFAMILY SSF54747 2 71 1.96E-28 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 138 6.0E-27 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 SMART SM00649 8 139 2.9E-85 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 Gene3D G3DSA:1.10.10.2720 72 147 1.0E-33 T 14-10-2018 Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 35 72 3.0E-15 T 14-10-2018 Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 Gene3D G3DSA:3.30.1550.10 1 71 2.1E-34 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 ProSitePatterns PS00359 Ribosomal protein L11 signature. 125 140 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 Pfam PF03946 Ribosomal protein L11, N-terminal domain 8 65 2.5E-27 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal Theos_1947 fc55a16d2372d272819a9a4554384aa3 147 SUPERFAMILY SSF46906 66 139 1.57E-27 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily Theos_0997 001177501de85a4fe29f46e72dc1e48a 251 Gene3D G3DSA:2.60.120.200 45 242 1.7E-17 T 14-10-2018 Theos_0997 001177501de85a4fe29f46e72dc1e48a 251 SUPERFAMILY SSF49899 26 241 1.58E-19 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Theos_0997 001177501de85a4fe29f46e72dc1e48a 251 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 91 241 6.0E-13 T 14-10-2018 Theos_2014 b9bc9e81e02de83b0fe009680717d332 442 ProSitePatterns PS01219 Ammonium transporters signature. 174 199 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 Theos_2014 b9bc9e81e02de83b0fe009680717d332 442 SUPERFAMILY SSF111352 22 397 1.27E-120 T 14-10-2018 Theos_2014 b9bc9e81e02de83b0fe009680717d332 442 Gene3D G3DSA:1.10.3430.10 9 426 4.0E-138 T 14-10-2018 IPR029020 Ammonium/urea transporter Theos_2014 b9bc9e81e02de83b0fe009680717d332 442 Pfam PF00909 Ammonium Transporter Family 27 417 1.2E-117 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Theos_2014 b9bc9e81e02de83b0fe009680717d332 442 TIGRFAM TIGR00836 amt: ammonium transporter 25 417 8.2E-131 T 14-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 Theos_0639 082b800d6f56eb1daa8b57aeb346e9ac 220 ProSitePatterns PS00856 Guanylate kinase-like signature. 36 53 - T 14-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 Theos_0639 082b800d6f56eb1daa8b57aeb346e9ac 220 Gene3D G3DSA:3.30.63.10 33 92 7.9E-64 T 14-10-2018 Theos_0639 082b800d6f56eb1daa8b57aeb346e9ac 220 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 3 180 1.8E-69 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 Theos_0639 082b800d6f56eb1daa8b57aeb346e9ac 220 Hamap MF_00328 Guanylate kinase [gmk]. 1 183 35.982 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 Theos_0639 082b800d6f56eb1daa8b57aeb346e9ac 220 SMART SM00072 2 183 2.6E-74 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit Theos_0639 082b800d6f56eb1daa8b57aeb346e9ac 220 Pfam PF00625 Guanylate kinase 3 180 4.3E-45 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit Theos_0639 082b800d6f56eb1daa8b57aeb346e9ac 220 Gene3D G3DSA:3.40.50.300 7 179 7.9E-64 T 14-10-2018 Theos_0639 082b800d6f56eb1daa8b57aeb346e9ac 220 SUPERFAMILY SSF52540 2 186 1.0E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1703 e768d9f2ba5410596deb6daf8aed2ec1 426 SMART SM01329 29 421 4.2E-175 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Theos_1703 e768d9f2ba5410596deb6daf8aed2ec1 426 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 426 1.4E-208 T 14-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Theos_1703 e768d9f2ba5410596deb6daf8aed2ec1 426 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 30 420 1.9E-112 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Theos_1703 e768d9f2ba5410596deb6daf8aed2ec1 426 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 306 325 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 Theos_1703 e768d9f2ba5410596deb6daf8aed2ec1 426 Gene3D G3DSA:3.40.718.10 1 426 7.7E-175 T 14-10-2018 Theos_1703 e768d9f2ba5410596deb6daf8aed2ec1 426 SUPERFAMILY SSF53659 4 425 4.14E-140 T 14-10-2018 Theos_1919 8b6965e9f70ba3f1d37f482130de8377 306 Gene3D G3DSA:3.40.109.10 1 238 1.5E-56 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Theos_1919 8b6965e9f70ba3f1d37f482130de8377 306 SUPERFAMILY SSF55469 2 216 1.83E-55 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Theos_1919 8b6965e9f70ba3f1d37f482130de8377 306 Pfam PF00881 Nitroreductase family 8 161 5.0E-22 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Theos_0878 af1b9de21fccf9503e9c7e557d3c4f47 148 SUPERFAMILY SSF55961 1 141 6.34E-28 T 14-10-2018 Theos_0878 af1b9de21fccf9503e9c7e557d3c4f47 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 142 1.2E-16 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase Theos_0878 af1b9de21fccf9503e9c7e557d3c4f47 148 Gene3D G3DSA:3.30.530.20 1 146 1.1E-40 T 14-10-2018 IPR023393 START-like domain superfamily Theos_1378 842a4e60505d70afd72f961fc6e03f22 358 PIRSF PIRSF039026 1 354 3.2E-121 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like Theos_1378 842a4e60505d70afd72f961fc6e03f22 358 Gene3D G3DSA:3.40.190.10 151 321 5.4E-123 T 14-10-2018 Theos_1378 842a4e60505d70afd72f961fc6e03f22 358 Gene3D G3DSA:3.40.190.170 31 335 5.4E-123 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Theos_1378 842a4e60505d70afd72f961fc6e03f22 358 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 321 1.0E-56 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 9.3E-24 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 PRINTS PR00149 Fumarate lyase superfamily signature 269 285 9.3E-24 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 9.3E-24 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 PRINTS PR00149 Fumarate lyase superfamily signature 224 251 9.3E-24 T 14-10-2018 IPR000362 Fumarate lyase family Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 Pfam PF00206 Lyase 6 290 1.2E-50 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 Gene3D G3DSA:1.10.40.30 357 436 1.3E-26 T 14-10-2018 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 Gene3D G3DSA:1.20.200.10 101 356 1.9E-91 T 14-10-2018 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 ProSitePatterns PS00163 Fumarate lyases signature. 269 278 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 SMART SM00998 357 435 2.3E-34 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 Gene3D G3DSA:1.10.275.10 1 100 3.5E-24 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 434 3.5E-136 T 14-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 SUPERFAMILY SSF48557 4 433 9.27E-121 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 5.8E-9 T 14-10-2018 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 PRINTS PR00145 Argininosuccinate lyase family signature 224 248 5.8E-9 T 14-10-2018 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 5.8E-9 T 14-10-2018 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 PRINTS PR00145 Argininosuccinate lyase family signature 269 285 5.8E-9 T 14-10-2018 Theos_0322 894dae47c7b3f77ef9dfd5816eb9c0d2 436 Pfam PF10397 Adenylosuccinate lyase C-terminus 358 434 6.2E-23 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0707 860c840e31fdcd343bd3b4ad6260f134 178 Gene3D G3DSA:1.20.120.1200 3 160 3.7E-46 T 14-10-2018 Theos_0707 860c840e31fdcd343bd3b4ad6260f134 178 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 16 156 1.3E-27 T 14-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_2278 8a43412d196a7d906174c01010ad191c 670 Gene3D G3DSA:3.30.2310.20 7 89 4.0E-6 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Theos_2278 8a43412d196a7d906174c01010ad191c 670 Pfam PF13245 AAA domain 234 470 4.3E-13 T 14-10-2018 Theos_2278 8a43412d196a7d906174c01010ad191c 670 Pfam PF13361 UvrD-like helicase C-terminal domain 595 658 1.7E-10 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Theos_2278 8a43412d196a7d906174c01010ad191c 670 SUPERFAMILY SSF143011 20 83 2.35E-9 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Theos_2278 8a43412d196a7d906174c01010ad191c 670 Gene3D G3DSA:3.40.50.300 489 667 1.3E-26 T 14-10-2018 Theos_2278 8a43412d196a7d906174c01010ad191c 670 SUPERFAMILY SSF52540 222 661 3.72E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0288 15cc75530d1a318e15803082a41e82ba 110 SMART SM00739 6 33 6.6E-7 T 14-10-2018 IPR005824 KOW Theos_0288 15cc75530d1a318e15803082a41e82ba 110 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 42 104 2.7E-25 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0288 15cc75530d1a318e15803082a41e82ba 110 Pfam PF00467 KOW motif 9 40 8.5E-10 T 14-10-2018 IPR005824 KOW Theos_0288 15cc75530d1a318e15803082a41e82ba 110 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 5 101 18.797 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0288 15cc75530d1a318e15803082a41e82ba 110 SUPERFAMILY SSF50104 4 104 3.12E-36 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Theos_0288 15cc75530d1a318e15803082a41e82ba 110 ProSitePatterns PS01108 Ribosomal protein L24 signature. 10 27 - T 14-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0288 15cc75530d1a318e15803082a41e82ba 110 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 5 104 6.7E-37 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0288 15cc75530d1a318e15803082a41e82ba 110 Gene3D G3DSA:2.30.30.30 1 104 9.7E-40 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 Theos_1059 801a053dd4d52df24c5336eae61db468 64 SUPERFAMILY SSF140683 2 62 4.58E-8 T 14-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily Theos_1059 801a053dd4d52df24c5336eae61db468 64 Pfam PF04405 Domain of Unknown function (DUF542) 7 58 2.4E-13 T 14-10-2018 IPR019903 Repair of iron centres family Theos_1059 801a053dd4d52df24c5336eae61db468 64 Gene3D G3DSA:1.10.3910.10 2 63 1.0E-7 T 14-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily Theos_0706 1a92f59eb6bbb863b575af415caedfb9 95 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 3 90 1.3E-21 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like Theos_0706 1a92f59eb6bbb863b575af415caedfb9 95 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 95 18.343 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 Theos_1771 ab9fc2e876b5b3887cda084dcf7c3b73 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 281 1.2E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_1224 884f53dfe5355416ab32cafa6e426514 329 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1224 884f53dfe5355416ab32cafa6e426514 329 Pfam PF00005 ABC transporter 42 185 3.0E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1224 884f53dfe5355416ab32cafa6e426514 329 SMART SM00382 50 243 3.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1224 884f53dfe5355416ab32cafa6e426514 329 SUPERFAMILY SSF52540 32 255 5.05E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1224 884f53dfe5355416ab32cafa6e426514 329 Gene3D G3DSA:3.40.50.300 28 267 1.6E-53 T 14-10-2018 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 Pfam PF00889 Elongation factor TS 33 195 1.5E-40 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 Gene3D G3DSA:3.30.479.20 58 195 5.6E-62 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 ProSitePatterns PS01126 Elongation factor Ts signature 1. 10 25 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 Gene3D G3DSA:1.10.286.20 110 154 5.6E-62 T 14-10-2018 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 SUPERFAMILY SSF54713 55 195 9.42E-55 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 Gene3D G3DSA:1.10.8.10 1 54 1.1E-23 T 14-10-2018 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 SUPERFAMILY SSF46934 4 53 1.22E-15 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 4 93 7.7E-33 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_1329 5f214cb9976ae5050c71976b9c319e86 196 Hamap MF_00050 Elongation factor Ts [tsf]. 1 196 43.248 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Theos_1064 a3dd4006536c0552db5a26c6031a6bdc 327 Pfam PF03576 Peptidase family S58 13 313 3.5E-58 T 14-10-2018 IPR005321 Peptidase S58, DmpA Theos_1064 a3dd4006536c0552db5a26c6031a6bdc 327 SUPERFAMILY SSF56266 12 313 8.89E-64 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Theos_1064 a3dd4006536c0552db5a26c6031a6bdc 327 Gene3D G3DSA:3.60.70.12 10 323 1.2E-100 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Theos_0282 6f2c467e46bd430667f6dc235723d5cc 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 5.5E-35 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 Theos_0282 6f2c467e46bd430667f6dc235723d5cc 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0282 6f2c467e46bd430667f6dc235723d5cc 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 106 9.1E-40 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0282 6f2c467e46bd430667f6dc235723d5cc 113 SUPERFAMILY SSF54843 1 110 2.62E-42 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Theos_0282 6f2c467e46bd430667f6dc235723d5cc 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.402 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0282 6f2c467e46bd430667f6dc235723d5cc 113 Gene3D G3DSA:3.90.470.10 1 113 2.4E-47 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Theos_0311 ae6bd3e569143f23779dcea689b62c76 255 SUPERFAMILY SSF110997 110 174 7.06E-16 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Theos_0311 ae6bd3e569143f23779dcea689b62c76 255 Pfam PF05036 Sporulation related domain 187 254 1.7E-12 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 Theos_0311 ae6bd3e569143f23779dcea689b62c76 255 Pfam PF05036 Sporulation related domain 111 171 2.9E-15 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 Theos_0311 ae6bd3e569143f23779dcea689b62c76 255 Gene3D G3DSA:3.30.70.1070 112 178 1.2E-13 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Theos_0311 ae6bd3e569143f23779dcea689b62c76 255 Gene3D G3DSA:3.30.70.1070 189 254 9.4E-10 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Theos_0311 ae6bd3e569143f23779dcea689b62c76 255 SUPERFAMILY SSF110997 186 253 2.09E-11 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Theos_1007 7a0297361765e3b637471ca94898918c 402 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Theos_1007 7a0297361765e3b637471ca94898918c 402 Gene3D G3DSA:3.40.47.10 6 281 3.0E-173 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1007 7a0297361765e3b637471ca94898918c 402 Gene3D G3DSA:3.40.47.10 141 397 3.0E-173 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1007 7a0297361765e3b637471ca94898918c 402 SUPERFAMILY SSF53901 3 275 2.05E-88 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1007 7a0297361765e3b637471ca94898918c 402 Pfam PF02803 Thiolase, C-terminal domain 276 398 4.6E-48 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Theos_1007 7a0297361765e3b637471ca94898918c 402 SUPERFAMILY SSF53901 277 399 2.11E-46 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1007 7a0297361765e3b637471ca94898918c 402 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 Theos_1007 7a0297361765e3b637471ca94898918c 402 Pfam PF00108 Thiolase, N-terminal domain 6 267 1.4E-81 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Theos_1007 7a0297361765e3b637471ca94898918c 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 Theos_1007 7a0297361765e3b637471ca94898918c 402 PIRSF PIRSF000429 1 401 6.2E-144 T 14-10-2018 IPR002155 Thiolase GO:0016747 Theos_1007 7a0297361765e3b637471ca94898918c 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 4.3E-146 T 14-10-2018 IPR002155 Thiolase GO:0016747 Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 Pfam PF13167 GTP-binding GTPase N-terminal 203 290 1.7E-26 T 14-10-2018 IPR025121 GTPase HflX, N-terminal Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 Gene3D G3DSA:3.40.50.300 375 539 4.5E-30 T 14-10-2018 Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 445 463 1.3E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 378 398 1.3E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 187 535 1.3E-123 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 SUPERFAMILY SSF52540 376 537 1.21E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 Hamap MF_00900 GTPase HflX [hflX]. 205 541 41.24 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 Pfam PF01926 50S ribosome-binding GTPase 378 495 2.5E-13 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 Gene3D G3DSA:3.40.50.11060 197 316 5.5E-35 T 14-10-2018 Theos_0793 34d2ee52154da7f65d48e0630ff31f42 549 Pfam PF16360 GTP-binding GTPase Middle Region 292 370 7.4E-28 T 14-10-2018 IPR032305 GTP-binding protein, middle domain Theos_0560 0ce0261c44615fcc2555302ee9fba15d 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 46 3.4E-11 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Theos_0560 0ce0261c44615fcc2555302ee9fba15d 84 SUPERFAMILY SSF89447 6 65 7.43E-13 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Theos_0560 0ce0261c44615fcc2555302ee9fba15d 84 SMART SM00966 4 49 6.8E-14 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Theos_0560 0ce0261c44615fcc2555302ee9fba15d 84 Gene3D G3DSA:2.10.260.10 2 41 2.7E-12 T 14-10-2018 Theos_0560 0ce0261c44615fcc2555302ee9fba15d 84 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 44 2.8E-15 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Theos_0817 f5fdffa0fec213cefe90eec208950a0d 99 PRINTS PR00124 ATP synthase C subunit signature 33 52 7.2E-6 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Theos_0817 f5fdffa0fec213cefe90eec208950a0d 99 PRINTS PR00124 ATP synthase C subunit signature 71 96 7.2E-6 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Theos_0817 f5fdffa0fec213cefe90eec208950a0d 99 Gene3D G3DSA:1.20.120.610 4 97 5.9E-16 T 14-10-2018 Theos_0817 f5fdffa0fec213cefe90eec208950a0d 99 SUPERFAMILY SSF81333 31 96 5.49E-13 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily Theos_0817 f5fdffa0fec213cefe90eec208950a0d 99 Pfam PF00137 ATP synthase subunit C 37 95 4.1E-15 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 Theos_0558 b834a06ee35efbe45514eb2704bfc096 312 SUPERFAMILY SSF51735 100 281 7.62E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0558 b834a06ee35efbe45514eb2704bfc096 312 SUPERFAMILY SSF52283 2 134 2.65E-38 T 14-10-2018 Theos_0558 b834a06ee35efbe45514eb2704bfc096 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 280 3.6E-56 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Theos_0558 b834a06ee35efbe45514eb2704bfc096 312 Gene3D G3DSA:3.40.50.720 8 304 8.1E-121 T 14-10-2018 Theos_0558 b834a06ee35efbe45514eb2704bfc096 312 Gene3D G3DSA:3.40.50.720 98 279 8.1E-121 T 14-10-2018 Theos_0558 b834a06ee35efbe45514eb2704bfc096 312 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Theos_0558 b834a06ee35efbe45514eb2704bfc096 312 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 311 1.6E-36 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 Theos_0558 b834a06ee35efbe45514eb2704bfc096 312 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Theos_1099 0320d46c7c0cdcee69c420ea569b17d7 199 SMART SM00419 14 68 0.0035 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Theos_1099 0320d46c7c0cdcee69c420ea569b17d7 199 Pfam PF08279 HTH domain 12 49 8.1E-9 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 Theos_1099 0320d46c7c0cdcee69c420ea569b17d7 199 Gene3D G3DSA:1.10.10.10 1 84 1.9E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1099 0320d46c7c0cdcee69c420ea569b17d7 199 SUPERFAMILY SSF46785 4 180 3.1E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2076 a0b74da383be75cb948a9c5439b00eb8 79 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.2E-16 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Theos_2076 a0b74da383be75cb948a9c5439b00eb8 79 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.2E-16 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Theos_2076 a0b74da383be75cb948a9c5439b00eb8 79 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.2E-16 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Theos_2076 a0b74da383be75cb948a9c5439b00eb8 79 Pfam PF00037 4Fe-4S binding domain 34 55 5.8E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_2076 a0b74da383be75cb948a9c5439b00eb8 79 Gene3D G3DSA:3.30.70.20 2 78 2.3E-33 T 14-10-2018 Theos_2076 a0b74da383be75cb948a9c5439b00eb8 79 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_2076 a0b74da383be75cb948a9c5439b00eb8 79 SUPERFAMILY SSF54862 1 74 8.63E-21 T 14-10-2018 Theos_0926 daf96bb511a92f1ba6bc6a543cff2fea 406 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 133 194 4.8E-9 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Theos_0926 daf96bb511a92f1ba6bc6a543cff2fea 406 SMART SM00471 205 338 9.3E-5 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0926 daf96bb511a92f1ba6bc6a543cff2fea 406 TIGRFAM TIGR00277 HDIG: HDIG domain 200 271 9.9E-13 T 14-10-2018 IPR006675 HDIG domain Theos_0926 daf96bb511a92f1ba6bc6a543cff2fea 406 Pfam PF01966 HD domain 211 326 5.8E-14 T 14-10-2018 IPR006674 HD domain Theos_0926 daf96bb511a92f1ba6bc6a543cff2fea 406 SUPERFAMILY SSF81301 1 100 1.96E-14 T 14-10-2018 Theos_0926 daf96bb511a92f1ba6bc6a543cff2fea 406 Pfam PF01743 Poly A polymerase head domain 1 61 4.2E-5 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Theos_0926 daf96bb511a92f1ba6bc6a543cff2fea 406 Gene3D G3DSA:1.10.3090.10 105 396 1.7E-30 T 14-10-2018 Theos_0926 daf96bb511a92f1ba6bc6a543cff2fea 406 Gene3D G3DSA:3.30.460.10 1 101 2.3E-14 T 14-10-2018 Theos_0926 daf96bb511a92f1ba6bc6a543cff2fea 406 SUPERFAMILY SSF81891 109 399 6.41E-41 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 SUPERFAMILY SSF56235 3 523 5.02E-161 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 Gene3D G3DSA:1.10.246.130 244 347 6.8E-23 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 Gene3D G3DSA:3.60.20.40 348 523 1.3E-54 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 Pfam PF01019 Gamma-glutamyltranspeptidase 35 519 3.2E-142 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 257 276 1.5E-40 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 370 388 1.5E-40 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 401 416 1.5E-40 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 425 442 1.5E-40 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 42 67 1.5E-40 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 107 125 1.5E-40 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 125 144 1.5E-40 T 14-10-2018 Theos_1078 862f1d17a8adf52be5a187d72a5a96b8 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 228 244 1.5E-40 T 14-10-2018 Theos_0106 7ce83676dea23333deb91388c9c00235 241 SUPERFAMILY SSF46626 104 237 1.01E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_0106 7ce83676dea23333deb91388c9c00235 241 Gene3D G3DSA:1.10.760.10 144 241 4.2E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_0106 7ce83676dea23333deb91388c9c00235 241 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 157 229 2.9E-17 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0106 7ce83676dea23333deb91388c9c00235 241 PRINTS PR00605 Class IC cytochrome C signature 207 229 3.9E-7 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 Theos_0106 7ce83676dea23333deb91388c9c00235 241 PRINTS PR00605 Class IC cytochrome C signature 167 178 3.9E-7 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 Theos_0202 a1d45b5323854dd745c3316e69d74203 385 SUPERFAMILY SSF51713 3 365 1.44E-149 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Theos_0202 a1d45b5323854dd745c3316e69d74203 385 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 365 5.4E-148 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Theos_0202 a1d45b5323854dd745c3316e69d74203 385 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 365 54.678 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Theos_0202 a1d45b5323854dd745c3316e69d74203 385 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 362 2.1E-86 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Theos_0202 a1d45b5323854dd745c3316e69d74203 385 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 365 4.5E-142 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Theos_0202 a1d45b5323854dd745c3316e69d74203 385 Gene3D G3DSA:3.20.20.105 1 371 3.5E-158 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Theos_0945 a6d96c5e34c45d7022d89463eac7f6ed 86 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 69 1.4E-17 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Theos_0945 a6d96c5e34c45d7022d89463eac7f6ed 86 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 49 9.2E-12 T 14-10-2018 Theos_0945 a6d96c5e34c45d7022d89463eac7f6ed 86 Gene3D G3DSA:3.40.1620.10 1 51 6.3E-20 T 14-10-2018 Theos_0945 a6d96c5e34c45d7022d89463eac7f6ed 86 SUPERFAMILY SSF143120 4 48 1.24E-10 T 14-10-2018 IPR036165 YefM-like superfamily Theos_2001 b21e2b5e3651087c989be0233b8b324d 263 PIRSF PIRSF020623 1 259 4.4E-68 T 14-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 Theos_2001 b21e2b5e3651087c989be0233b8b324d 263 Pfam PF07848 PaaX-like protein 2 70 1.1E-22 T 14-10-2018 IPR012906 PaaX-like, N-terminal Theos_2001 b21e2b5e3651087c989be0233b8b324d 263 Gene3D G3DSA:1.10.10.10 1 83 9.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2001 b21e2b5e3651087c989be0233b8b324d 263 Pfam PF08223 PaaX-like protein C-terminal domain 171 244 1.2E-15 T 14-10-2018 IPR013225 PaaX-like, C-terminal Theos_2430 44fe2d531ce642d24408a0e21801521d 274 Gene3D G3DSA:1.10.3720.10 64 270 2.6E-26 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2430 44fe2d531ce642d24408a0e21801521d 274 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 50 2.2E-9 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Theos_2430 44fe2d531ce642d24408a0e21801521d 274 SUPERFAMILY SSF161098 69 255 8.76E-30 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2430 44fe2d531ce642d24408a0e21801521d 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 274 2.7E-35 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1770 760e69ead6d50a66e3fc7a9a9f810ad1 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 330 2.0E-43 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_0025 dd3bc0f5cdbca768c7403ecbf9942754 155 SUPERFAMILY SSF55811 4 127 2.44E-24 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Theos_0025 dd3bc0f5cdbca768c7403ecbf9942754 155 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Theos_0025 dd3bc0f5cdbca768c7403ecbf9942754 155 Gene3D G3DSA:3.90.79.10 3 152 1.1E-25 T 14-10-2018 Theos_0025 dd3bc0f5cdbca768c7403ecbf9942754 155 PRINTS PR00502 NUDIX hydrolase family signature 48 63 5.1E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_0025 dd3bc0f5cdbca768c7403ecbf9942754 155 PRINTS PR00502 NUDIX hydrolase family signature 34 48 5.1E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_0025 dd3bc0f5cdbca768c7403ecbf9942754 155 Pfam PF00293 NUDIX domain 7 119 2.3E-20 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Theos_0213 378d0f14c290a30d62eaee8930d15027 272 Gene3D G3DSA:2.170.120.30 29 114 1.6E-9 T 14-10-2018 Theos_2233 39f01e258e087472f27caca88cae45a5 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 280 8.9E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_0701 f3cb16960a1baff24b7d41fc3782487f 539 SUPERFAMILY SSF48452 158 238 6.24E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0701 f3cb16960a1baff24b7d41fc3782487f 539 Gene3D G3DSA:1.25.40.10 141 282 7.7E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0701 f3cb16960a1baff24b7d41fc3782487f 539 Gene3D G3DSA:1.10.530.10 384 538 6.2E-38 T 14-10-2018 Theos_0701 f3cb16960a1baff24b7d41fc3782487f 539 SUPERFAMILY SSF53955 389 537 1.19E-38 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Theos_0701 f3cb16960a1baff24b7d41fc3782487f 539 Pfam PF13432 Tetratricopeptide repeat 159 210 8.6E-8 T 14-10-2018 Theos_0701 f3cb16960a1baff24b7d41fc3782487f 539 Pfam PF01464 Transglycosylase SLT domain 397 504 6.0E-23 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 Theos_1633 ccc025c992c60e165f1b3e356af7c246 387 SUPERFAMILY SSF103473 11 380 5.23E-46 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1633 ccc025c992c60e165f1b3e356af7c246 387 Gene3D G3DSA:1.20.1720.10 10 383 5.0E-71 T 14-10-2018 Theos_1633 ccc025c992c60e165f1b3e356af7c246 387 Pfam PF07690 Major Facilitator Superfamily 18 350 2.9E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_2223 7f56b1b5c2a8689b6121c41dce3e671b 129 Gene3D G3DSA:3.30.460.10 6 99 8.2E-11 T 14-10-2018 Theos_2223 7f56b1b5c2a8689b6121c41dce3e671b 129 SUPERFAMILY SSF81301 2 121 7.64E-16 T 14-10-2018 Theos_2223 7f56b1b5c2a8689b6121c41dce3e671b 129 Pfam PF01909 Nucleotidyltransferase domain 18 59 1.5E-8 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Theos_1076 60a5142eb0577c359bd5be19bfafd4bc 293 Gene3D G3DSA:3.20.20.410 1 293 1.4E-74 T 14-10-2018 IPR036520 UPF0759 superfamily Theos_1076 60a5142eb0577c359bd5be19bfafd4bc 293 Pfam PF01904 Protein of unknown function DUF72 22 287 3.3E-58 T 14-10-2018 IPR002763 Protein of unknown function DUF72 Theos_1076 60a5142eb0577c359bd5be19bfafd4bc 293 SUPERFAMILY SSF117396 2 291 2.49E-68 T 14-10-2018 IPR036520 UPF0759 superfamily Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 Gene3D G3DSA:3.90.640.10 229 293 8.4E-102 T 14-10-2018 Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 SUPERFAMILY SSF53067 192 371 9.18E-43 T 14-10-2018 Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 PIRSF PIRSF003101 1 410 1.9E-126 T 14-10-2018 IPR020823 Cell division protein FtsA Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 Gene3D G3DSA:3.30.1490.110 80 163 8.4E-102 T 14-10-2018 Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 3 372 4.2E-113 T 14-10-2018 IPR020823 Cell division protein FtsA Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 SUPERFAMILY SSF53067 2 191 4.66E-51 T 14-10-2018 Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 Pfam PF14450 Cell division protein FtsA 202 368 5.1E-24 T 14-10-2018 Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 SMART SM00842 3 190 5.8E-88 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 Gene3D G3DSA:3.30.420.40 191 346 8.4E-102 T 14-10-2018 Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 Hamap MF_02033 Cell division protein FtsA [ftsA]. 1 410 27.938 T 14-10-2018 IPR020823 Cell division protein FtsA Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 Pfam PF02491 SHS2 domain inserted in FTSA 78 155 1.7E-25 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 Theos_1131 6d85f0cc956aa35cad036bc9d7447c26 410 Gene3D G3DSA:3.30.420.40 6 366 8.4E-102 T 14-10-2018 Theos_1087 d72a1fd578bc3ad7b20e4252785d845f 395 Pfam PF12802 MarR family 14 57 2.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_1087 d72a1fd578bc3ad7b20e4252785d845f 395 ProSitePatterns PS01125 ROK family signature. 199 226 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Theos_1087 d72a1fd578bc3ad7b20e4252785d845f 395 Gene3D G3DSA:3.30.420.40 196 343 8.7E-38 T 14-10-2018 Theos_1087 d72a1fd578bc3ad7b20e4252785d845f 395 SUPERFAMILY SSF53067 80 364 3.08E-47 T 14-10-2018 Theos_1087 d72a1fd578bc3ad7b20e4252785d845f 395 Gene3D G3DSA:3.30.420.40 76 195 1.9E-20 T 14-10-2018 Theos_1087 d72a1fd578bc3ad7b20e4252785d845f 395 Pfam PF00480 ROK family 82 361 1.1E-43 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Theos_1087 d72a1fd578bc3ad7b20e4252785d845f 395 SUPERFAMILY SSF46785 9 70 1.13E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1087 d72a1fd578bc3ad7b20e4252785d845f 395 Gene3D G3DSA:1.10.10.10 1 75 2.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 3 145 2.5E-52 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 140 2.0E-55 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 48 66 4.5E-30 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 114 133 4.5E-30 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 72 90 4.5E-30 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 4.5E-30 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 Gene3D G3DSA:3.30.1360.80 1 150 2.0E-55 T 14-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 SUPERFAMILY SSF63411 4 147 1.74E-55 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 150 34.81 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0653 42ccd30e692e40ffb8a7836993ea22eb 150 PIRSF PIRSF006160 1 149 1.1E-58 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 2.2E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 2.2E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 Gene3D G3DSA:3.30.565.10 305 424 1.1E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 291 2.6E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 419 1.5E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 SUPERFAMILY SSF55874 315 420 2.62E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 SMART SM00388 230 292 6.3E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 Gene3D G3DSA:1.10.287.130 175 292 1.9E-17 T 14-10-2018 Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 SMART SM00387 320 421 1.9E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0352 f836e808f75f58fca64a9b2d9f8022a2 434 SUPERFAMILY SSF47384 213 291 8.24E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 SUPERFAMILY SSF88659 271 347 7.85E-20 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 Pfam PF04545 Sigma-70, region 4 368 420 2.5E-18 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 Pfam PF04542 Sigma-70 region 2 198 267 4.3E-20 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 Pfam PF04539 Sigma-70 region 3 277 355 3.7E-26 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 Gene3D G3DSA:1.20.120.1810 85 267 2.3E-79 T 14-10-2018 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 Pfam PF00140 Sigma-70 factor, region 1.2 90 123 1.5E-16 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 3 434 33.699 T 14-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 SUPERFAMILY SSF88659 330 422 1.05E-28 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 194 420 1.1E-39 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 Gene3D G3DSA:1.10.10.10 350 431 2.7E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 SUPERFAMILY SSF88946 87 268 9.55E-59 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 Gene3D G3DSA:1.10.10.10 271 349 3.0E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 PRINTS PR00046 Major sigma-70 factor signature 408 419 1.9E-27 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 PRINTS PR00046 Major sigma-70 factor signature 222 235 1.9E-27 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 PRINTS PR00046 Major sigma-70 factor signature 372 384 1.9E-27 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 PRINTS PR00046 Major sigma-70 factor signature 393 408 1.9E-27 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 PRINTS PR00046 Major sigma-70 factor signature 246 254 1.9E-27 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 393 419 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Theos_0760 f51c7b4cf6c9c97221d7e82ed610185b 434 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 194 433 5.6E-116 T 14-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 Theos_0432 4b69a8a6aa15778167f24f596a8fcd23 341 Gene3D G3DSA:1.20.1090.10 162 338 1.4E-51 T 14-10-2018 Theos_0432 4b69a8a6aa15778167f24f596a8fcd23 341 PIRSF PIRSF001455 1 340 7.7E-89 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Theos_0432 4b69a8a6aa15778167f24f596a8fcd23 341 Pfam PF01761 3-dehydroquinate synthase 58 304 3.5E-72 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Theos_0432 4b69a8a6aa15778167f24f596a8fcd23 341 SUPERFAMILY SSF56796 1 337 1.7E-82 T 14-10-2018 Theos_0432 4b69a8a6aa15778167f24f596a8fcd23 341 Gene3D G3DSA:3.40.50.1970 1 161 2.0E-50 T 14-10-2018 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 SMART SM00228 236 333 5.8E-12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 Gene3D G3DSA:2.30.42.10 246 348 7.9E-27 T 14-10-2018 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 Pfam PF13365 Trypsin-like peptidase domain 55 197 3.7E-22 T 14-10-2018 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 SUPERFAMILY SSF50156 223 341 2.37E-17 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 SUPERFAMILY SSF50494 29 231 1.11E-40 T 14-10-2018 IPR009003 Peptidase S1, PA clan Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 PRINTS PR00834 HtrA/DegQ protease family signature 190 207 1.2E-22 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 PRINTS PR00834 HtrA/DegQ protease family signature 63 75 1.2E-22 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 PRINTS PR00834 HtrA/DegQ protease family signature 84 104 1.2E-22 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 PRINTS PR00834 HtrA/DegQ protease family signature 168 185 1.2E-22 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 PRINTS PR00834 HtrA/DegQ protease family signature 291 303 1.2E-22 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 PRINTS PR00834 HtrA/DegQ protease family signature 127 151 1.2E-22 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 Gene3D G3DSA:2.40.10.120 17 232 8.9E-38 T 14-10-2018 Theos_1714 f061b234f1123dae1ab4bcdb1dbbc774 348 Pfam PF13180 PDZ domain 237 341 6.0E-16 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_1872 f3094ce31236a8a7d07b2f7d72de48e3 319 SUPERFAMILY SSF51430 4 316 3.54E-96 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Theos_1872 f3094ce31236a8a7d07b2f7d72de48e3 319 Gene3D G3DSA:3.20.20.100 3 318 4.6E-113 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Theos_1872 f3094ce31236a8a7d07b2f7d72de48e3 319 Pfam PF00248 Aldo/keto reductase family 18 315 3.1E-70 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain Theos_1872 f3094ce31236a8a7d07b2f7d72de48e3 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 258 270 5.5E-10 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 Theos_1872 f3094ce31236a8a7d07b2f7d72de48e3 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 113 123 5.5E-10 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 Theos_1872 f3094ce31236a8a7d07b2f7d72de48e3 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 271 284 5.5E-10 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 Theos_1872 f3094ce31236a8a7d07b2f7d72de48e3 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 164 183 5.5E-10 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 Theos_2024 884e2fb8da9d92b82fd872f80e6c002a 121 Gene3D G3DSA:3.10.129.10 1 121 6.3E-35 T 14-10-2018 Theos_2024 884e2fb8da9d92b82fd872f80e6c002a 121 Pfam PF03061 Thioesterase superfamily 18 88 2.5E-17 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Theos_2024 884e2fb8da9d92b82fd872f80e6c002a 121 SUPERFAMILY SSF54637 4 119 3.88E-34 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_0517 96f07baea057cb0df13ba5e51dc44fb2 151 SUPERFAMILY SSF50800 5 147 1.41E-26 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily Theos_0517 96f07baea057cb0df13ba5e51dc44fb2 151 Gene3D G3DSA:2.40.33.20 3 151 7.5E-27 T 14-10-2018 Theos_0517 96f07baea057cb0df13ba5e51dc44fb2 151 Pfam PF03473 MOSC domain 46 145 3.6E-6 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 Theos_0464 dda5464cc4c1e23a17e6f1f04a5ebbc3 327 Pfam PF00483 Nucleotidyl transferase 5 251 8.4E-32 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Theos_0464 dda5464cc4c1e23a17e6f1f04a5ebbc3 327 Gene3D G3DSA:3.90.550.10 4 323 3.9E-90 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_0464 dda5464cc4c1e23a17e6f1f04a5ebbc3 327 SUPERFAMILY SSF53448 2 251 5.86E-55 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_0464 dda5464cc4c1e23a17e6f1f04a5ebbc3 327 SUPERFAMILY SSF159283 258 321 8.5E-11 T 14-10-2018 Theos_2038 e525b298895c2537bed492cfcddd28bf 617 SUPERFAMILY SSF55486 319 410 2.32E-7 T 14-10-2018 Theos_2038 e525b298895c2537bed492cfcddd28bf 617 Pfam PF10462 Peptidase M66 338 408 5.0E-5 T 14-10-2018 IPR019503 Peptidase M66 domain GO:0004222 Theos_0050 e62c58c5bf86913d4aa569b87f4f023f 79 Pfam PF08972 Domain of unknown function (DUF1902) 10 75 2.0E-28 T 14-10-2018 IPR015066 Domain of unknown function DUF1902 Theos_0050 e62c58c5bf86913d4aa569b87f4f023f 79 Gene3D G3DSA:3.30.2390.10 7 79 9.7E-33 T 14-10-2018 Theos_0050 e62c58c5bf86913d4aa569b87f4f023f 79 SUPERFAMILY SSF143100 10 70 7.32E-16 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like Theos_0308 067fe80effda3369f939960e777a2958 278 SUPERFAMILY SSF103481 37 138 2.22E-13 T 14-10-2018 Theos_0308 067fe80effda3369f939960e777a2958 278 Pfam PF00892 EamA-like transporter family 147 275 5.0E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_0308 067fe80effda3369f939960e777a2958 278 Pfam PF00892 EamA-like transporter family 1 133 3.7E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_0308 067fe80effda3369f939960e777a2958 278 SUPERFAMILY SSF103481 178 275 2.48E-13 T 14-10-2018 Theos_1090 107f7b18e7a07034ffbefc0828dd5843 268 Gene3D G3DSA:1.10.3720.10 1 255 2.0E-57 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1090 107f7b18e7a07034ffbefc0828dd5843 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 260 4.2E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1090 107f7b18e7a07034ffbefc0828dd5843 268 SUPERFAMILY SSF161098 2 268 3.46E-67 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.1E-10 T 14-10-2018 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 319 341 1.1E-10 T 14-10-2018 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-10 T 14-10-2018 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 SUPERFAMILY SSF51905 2 372 2.2E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 Gene3D G3DSA:3.90.700.10 220 311 8.6E-129 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 Pfam PF00890 FAD binding domain 4 356 6.2E-86 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 341 1.5E-5 T 14-10-2018 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.5E-5 T 14-10-2018 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 Pfam PF02910 Fumarate reductase flavoprotein C-term 436 469 4.4E-9 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 SUPERFAMILY SSF46977 396 476 1.96E-17 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 Gene3D G3DSA:1.20.58.100 385 469 6.3E-14 T 14-10-2018 Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 Gene3D G3DSA:3.50.50.60 4 367 8.6E-129 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1012 711dfa79d3b53a7162cf04c6869e48d3 481 SUPERFAMILY SSF56425 210 316 1.08E-33 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1141 0e7f795749eb4eb1db0e8c1a72cf0bfa 287 SUPERFAMILY SSF51735 1 251 1.58E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1141 0e7f795749eb4eb1db0e8c1a72cf0bfa 287 Gene3D G3DSA:3.40.50.720 2 238 3.2E-49 T 14-10-2018 Theos_1141 0e7f795749eb4eb1db0e8c1a72cf0bfa 287 Pfam PF13460 NAD(P)H-binding 7 140 2.2E-16 T 14-10-2018 IPR016040 NAD(P)-binding domain Theos_2348 b3e7aa6bd9996506e923695b27c1517d 285 Gene3D G3DSA:3.40.50.1980 1 144 2.7E-16 T 14-10-2018 Theos_2348 b3e7aa6bd9996506e923695b27c1517d 285 Gene3D G3DSA:3.40.50.1980 154 274 7.3E-9 T 14-10-2018 Theos_2348 b3e7aa6bd9996506e923695b27c1517d 285 SUPERFAMILY SSF53807 2 273 9.42E-24 T 14-10-2018 Theos_2099 41872fa46449f5bf8e4548163d75c58d 324 SUPERFAMILY SSF52922 188 323 2.49E-39 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_2099 41872fa46449f5bf8e4548163d75c58d 324 Gene3D G3DSA:3.40.50.920 193 324 2.5E-45 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_2099 41872fa46449f5bf8e4548163d75c58d 324 Gene3D G3DSA:3.40.50.970 1 192 3.5E-97 T 14-10-2018 Theos_2099 41872fa46449f5bf8e4548163d75c58d 324 Pfam PF02780 Transketolase, C-terminal domain 194 313 1.3E-33 T 14-10-2018 IPR033248 Transketolase, C-terminal domain Theos_2099 41872fa46449f5bf8e4548163d75c58d 324 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 2.2E-52 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_2099 41872fa46449f5bf8e4548163d75c58d 324 SMART SM00861 4 179 1.3E-76 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_2099 41872fa46449f5bf8e4548163d75c58d 324 SUPERFAMILY SSF52518 4 193 4.07E-75 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_1002 836bbad8358b5a71bfcd2f8b5a621735 421 SUPERFAMILY SSF51905 5 408 4.75E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1002 836bbad8358b5a71bfcd2f8b5a621735 421 Pfam PF01266 FAD dependent oxidoreductase 6 388 7.8E-33 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Theos_1002 836bbad8358b5a71bfcd2f8b5a621735 421 Gene3D G3DSA:3.30.9.10 81 350 4.3E-43 T 14-10-2018 Theos_1002 836bbad8358b5a71bfcd2f8b5a621735 421 Gene3D G3DSA:3.50.50.60 7 396 4.3E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1038 18a4ddef868a2d587b0b36f1ae35b6bc 225 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 4 217 3.3E-38 T 14-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 Theos_1038 18a4ddef868a2d587b0b36f1ae35b6bc 225 Gene3D G3DSA:1.20.950.20 2 212 7.8E-61 T 14-10-2018 Theos_1038 18a4ddef868a2d587b0b36f1ae35b6bc 225 SUPERFAMILY SSF103501 3 217 6.02E-50 T 14-10-2018 IPR036197 NarG-like superfamily Theos_1038 18a4ddef868a2d587b0b36f1ae35b6bc 225 Pfam PF02665 Nitrate reductase gamma subunit 6 219 1.4E-59 T 14-10-2018 IPR023234 NarG-like domain Theos_2243 612b068ef850904e0e3c738fa2cfdc5e 506 SUPERFAMILY SSF51004 50 236 7.85E-7 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 Gene3D G3DSA:1.10.1200.140 356 437 1.9E-97 T 14-10-2018 Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 Gene3D G3DSA:3.40.720.10 34 439 1.9E-97 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 SMART SM00098 34 467 9.5E-44 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 PRINTS PR00113 Alkaline phosphatase signature 124 144 4.0E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 PRINTS PR00113 Alkaline phosphatase signature 168 178 4.0E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 PRINTS PR00113 Alkaline phosphatase signature 241 270 4.0E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 PRINTS PR00113 Alkaline phosphatase signature 33 53 4.0E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 PRINTS PR00113 Alkaline phosphatase signature 87 102 4.0E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 Pfam PF00245 Alkaline phosphatase 33 466 5.3E-69 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Theos_2341 45982a86fbb23253df2ce5674b27dcad 499 SUPERFAMILY SSF53649 27 471 1.16E-100 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Theos_0613 a4ff5e4b3d90184228ef6cbd881646cb 496 Gene3D G3DSA:3.40.50.300 1 242 5.6E-58 T 14-10-2018 Theos_0613 a4ff5e4b3d90184228ef6cbd881646cb 496 SUPERFAMILY SSF52540 266 484 2.24E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0613 a4ff5e4b3d90184228ef6cbd881646cb 496 Pfam PF00005 ABC transporter 268 423 1.2E-13 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0613 a4ff5e4b3d90184228ef6cbd881646cb 496 SMART SM00382 29 247 5.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0613 a4ff5e4b3d90184228ef6cbd881646cb 496 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0613 a4ff5e4b3d90184228ef6cbd881646cb 496 Pfam PF00005 ABC transporter 21 169 4.5E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0613 a4ff5e4b3d90184228ef6cbd881646cb 496 Gene3D G3DSA:3.40.50.300 254 492 7.0E-39 T 14-10-2018 Theos_0613 a4ff5e4b3d90184228ef6cbd881646cb 496 SUPERFAMILY SSF52540 4 224 1.93E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1961 25c54705ef0f777dacf789625f9e9b3d 267 Gene3D G3DSA:3.20.20.140 1 267 2.0E-84 T 14-10-2018 Theos_1961 25c54705ef0f777dacf789625f9e9b3d 267 Pfam PF02811 PHP domain 3 193 1.4E-9 T 14-10-2018 IPR004013 PHP domain GO:0003824 Theos_1961 25c54705ef0f777dacf789625f9e9b3d 267 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 3 238 2.9E-54 T 14-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 Theos_1961 25c54705ef0f777dacf789625f9e9b3d 267 SUPERFAMILY SSF89550 1 255 6.41E-51 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Theos_0179 16b339d7cdecc233998b5100096ed06e 185 Pfam PF13563 2'-5' RNA ligase superfamily 18 153 5.6E-17 T 14-10-2018 Theos_0179 16b339d7cdecc233998b5100096ed06e 185 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 169 23.727 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Theos_0179 16b339d7cdecc233998b5100096ed06e 185 SUPERFAMILY SSF55144 1 171 2.44E-49 T 14-10-2018 IPR009097 Cyclic phosphodiesterase Theos_0179 16b339d7cdecc233998b5100096ed06e 185 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 169 2.8E-35 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Theos_0179 16b339d7cdecc233998b5100096ed06e 185 Gene3D G3DSA:3.90.1140.10 1 185 2.2E-58 T 14-10-2018 Theos_2498 a5a614b783485a7d98c0a89fe3d2bdec 126 Pfam PF00436 Single-strand binding protein family 9 94 8.4E-15 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Theos_2498 a5a614b783485a7d98c0a89fe3d2bdec 126 Gene3D G3DSA:2.40.50.140 2 113 8.2E-19 T 14-10-2018 Theos_2498 a5a614b783485a7d98c0a89fe3d2bdec 126 PIRSF PIRSF002070 2 123 3.4E-14 T 14-10-2018 Theos_2498 a5a614b783485a7d98c0a89fe3d2bdec 126 SUPERFAMILY SSF50249 7 110 2.71E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0948 ab140b162f665290966042503c4f6d08 331 Gene3D G3DSA:3.40.50.970 7 197 7.1E-82 T 14-10-2018 Theos_0948 ab140b162f665290966042503c4f6d08 331 SUPERFAMILY SSF52518 6 208 7.5E-69 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_0948 ab140b162f665290966042503c4f6d08 331 Pfam PF02780 Transketolase, C-terminal domain 199 321 5.6E-37 T 14-10-2018 IPR033248 Transketolase, C-terminal domain Theos_0948 ab140b162f665290966042503c4f6d08 331 SUPERFAMILY SSF52922 194 330 1.57E-38 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_0948 ab140b162f665290966042503c4f6d08 331 Pfam PF02779 Transketolase, pyrimidine binding domain 9 183 2.0E-42 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_0948 ab140b162f665290966042503c4f6d08 331 SMART SM00861 9 184 4.1E-65 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_0948 ab140b162f665290966042503c4f6d08 331 Gene3D G3DSA:3.40.50.920 198 330 3.0E-45 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_1295 85eec85f209b0fe4d28ff2832cab411f 249 Pfam PF00005 ABC transporter 20 174 5.5E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1295 85eec85f209b0fe4d28ff2832cab411f 249 SUPERFAMILY SSF52540 4 231 1.28E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1295 85eec85f209b0fe4d28ff2832cab411f 249 SMART SM00382 29 222 4.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1295 85eec85f209b0fe4d28ff2832cab411f 249 Gene3D G3DSA:3.40.50.300 2 243 1.7E-54 T 14-10-2018 Theos_1295 85eec85f209b0fe4d28ff2832cab411f 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0927 98c66052369896f214abc6f3ea7035a4 208 Pfam PF01121 Dephospho-CoA kinase 11 184 1.4E-55 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Theos_0927 98c66052369896f214abc6f3ea7035a4 208 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 12 190 4.0E-41 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Theos_0927 98c66052369896f214abc6f3ea7035a4 208 Gene3D G3DSA:3.40.50.300 4 205 5.6E-67 T 14-10-2018 Theos_0927 98c66052369896f214abc6f3ea7035a4 208 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 10 200 25.917 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Theos_0927 98c66052369896f214abc6f3ea7035a4 208 SUPERFAMILY SSF52540 10 197 1.01E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0393 341a3b44359289f7f33ac788c9f3e3b3 183 SUPERFAMILY SSF117396 5 122 7.85E-10 T 14-10-2018 IPR036520 UPF0759 superfamily Theos_0393 341a3b44359289f7f33ac788c9f3e3b3 183 Gene3D G3DSA:3.20.20.410 1 128 1.4E-6 T 14-10-2018 IPR036520 UPF0759 superfamily Theos_0393 341a3b44359289f7f33ac788c9f3e3b3 183 Pfam PF01904 Protein of unknown function DUF72 16 97 1.8E-8 T 14-10-2018 IPR002763 Protein of unknown function DUF72 Theos_1895 22ec76f73c18d699e714896fc243022a 357 Gene3D G3DSA:1.20.1250.20 189 356 6.2E-9 T 14-10-2018 Theos_1895 22ec76f73c18d699e714896fc243022a 357 Gene3D G3DSA:1.20.1250.20 6 176 1.6E-13 T 14-10-2018 Theos_1895 22ec76f73c18d699e714896fc243022a 357 SUPERFAMILY SSF103473 6 352 2.75E-27 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1895 22ec76f73c18d699e714896fc243022a 357 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 14 349 4.3E-47 T 14-10-2018 IPR010645 Uncharacterised MFS-type transporter YbfB Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PIRSF PIRSF000350 1 452 8.0E-94 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 332 353 1.5E-75 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 397 412 1.5E-75 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 1.5E-75 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 1.5E-75 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 1.5E-75 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 419 439 1.5E-75 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 1.5E-75 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.5E-75 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 1.5E-75 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 317 1.2E-75 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 2 454 3.5E-164 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 Gene3D G3DSA:3.50.50.60 142 260 1.8E-128 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 SUPERFAMILY SSF51905 2 369 1.5E-66 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 3.3E-38 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 3.3E-38 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 3.3E-38 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 3.3E-38 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.3E-38 T 14-10-2018 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 336 445 1.5E-37 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 SUPERFAMILY SSF55424 333 454 2.75E-42 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 Gene3D G3DSA:3.30.390.30 335 455 1.4E-48 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Theos_0131 d3b1b70faf17ca9b503d51bc965a2024 455 Gene3D G3DSA:3.50.50.60 2 320 1.8E-128 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 5.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 SUPERFAMILY SSF51735 9 251 9.28E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 182 0.0012 T 14-10-2018 Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 Gene3D G3DSA:3.40.50.720 1 252 2.3E-78 T 14-10-2018 Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 249 3.5E-57 T 14-10-2018 Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 5.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1365 87cfb7a7e368230797d00fced2b20fa0 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 5.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0661 285fa128f6bea26f6681add7f802fe99 344 Pfam PF14332 Domain of unknown function (DUF4388) 5 158 4.0E-12 T 14-10-2018 IPR025497 Domain of unknown function DUF4388 Theos_0661 285fa128f6bea26f6681add7f802fe99 344 SUPERFAMILY SSF52172 232 340 4.66E-6 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0661 285fa128f6bea26f6681add7f802fe99 344 SUPERFAMILY SSF160246 53 108 1.78E-6 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Theos_0514 49490e98104f51aaeafc427f4ca33e7f 389 Gene3D G3DSA:3.40.50.2300 24 352 1.4E-91 T 14-10-2018 Theos_0514 49490e98104f51aaeafc427f4ca33e7f 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 45 61 3.0E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_0514 49490e98104f51aaeafc427f4ca33e7f 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 64 82 3.0E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_0514 49490e98104f51aaeafc427f4ca33e7f 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 23 39 3.0E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_0514 49490e98104f51aaeafc427f4ca33e7f 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 336 351 3.0E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_0514 49490e98104f51aaeafc427f4ca33e7f 389 Pfam PF13458 Periplasmic binding protein 23 368 9.9E-55 T 14-10-2018 IPR028081 Leucine-binding protein domain Theos_0514 49490e98104f51aaeafc427f4ca33e7f 389 SUPERFAMILY SSF53822 22 371 1.31E-82 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_0514 49490e98104f51aaeafc427f4ca33e7f 389 Gene3D G3DSA:3.40.50.2300 142 272 1.4E-91 T 14-10-2018 Theos_1806 9bd50fb4b90d55ab0c6b30315917e96c 406 Pfam PF05161 MOFRL family 301 399 3.5E-27 T 14-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 Theos_1806 9bd50fb4b90d55ab0c6b30315917e96c 406 SUPERFAMILY SSF82544 3 405 4.45E-114 T 14-10-2018 Theos_1806 9bd50fb4b90d55ab0c6b30315917e96c 406 Pfam PF13660 Domain of unknown function (DUF4147) 5 209 1.2E-61 T 14-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 Theos_1806 9bd50fb4b90d55ab0c6b30315917e96c 406 Gene3D G3DSA:3.40.1480.10 245 401 8.2E-110 T 14-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily Theos_1806 9bd50fb4b90d55ab0c6b30315917e96c 406 Gene3D G3DSA:3.40.50.10180 30 244 8.2E-110 T 14-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 Gene3D G3DSA:1.10.3210.10 12 203 2.1E-82 T 14-10-2018 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 35 728 3.5E-219 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 SMART SM00954 253 376 5.5E-66 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 Pfam PF02824 TGS domain 418 477 1.3E-23 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 Pfam PF04607 Region found in RelA / SpoT proteins 253 375 3.4E-35 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 Gene3D G3DSA:3.30.70.260 660 732 5.8E-6 T 14-10-2018 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 SMART SM00471 50 165 1.3E-12 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 SUPERFAMILY SSF55021 660 731 8.7E-8 T 14-10-2018 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 Gene3D G3DSA:3.30.460.10 205 356 8.1E-47 T 14-10-2018 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 SUPERFAMILY SSF81301 192 422 5.4E-61 T 14-10-2018 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 Pfam PF13328 HD domain 35 187 6.6E-53 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 Gene3D G3DSA:3.10.20.30 411 485 2.5E-35 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 SUPERFAMILY SSF81271 405 477 1.44E-22 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Theos_0054 cfefd90617e19934ee6abdb6be644cbf 732 SUPERFAMILY SSF109604 17 203 3.03E-73 T 14-10-2018 Theos_0097 5ab1042092356054143ee6c9bbfa9e78 65 Pfam PF00403 Heavy-metal-associated domain 4 60 4.0E-18 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Theos_0097 5ab1042092356054143ee6c9bbfa9e78 65 SUPERFAMILY SSF55008 2 64 7.33E-21 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Theos_0097 5ab1042092356054143ee6c9bbfa9e78 65 ProSitePatterns PS01047 Heavy-metal-associated domain. 6 35 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Theos_0097 5ab1042092356054143ee6c9bbfa9e78 65 Gene3D G3DSA:3.30.70.100 1 65 6.6E-28 T 14-10-2018 Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 SMART SM00400 34 88 1.2E-28 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 SMART SM00493 247 319 4.6E-10 T 14-10-2018 IPR006171 TOPRIM domain Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 Gene3D G3DSA:3.40.1360.10 229 352 2.7E-28 T 14-10-2018 Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 Pfam PF01807 CHC2 zinc finger 5 95 6.5E-30 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 SUPERFAMILY SSF57783 5 95 1.87E-30 T 14-10-2018 Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 Hamap MF_00974 DNA primase [dnaG]. 1 571 24.715 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 Pfam PF08275 DNA primase catalytic core, N-terminal domain 117 239 7.0E-37 T 14-10-2018 IPR013264 DNA primase, catalytic core, N-terminal Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 TIGRFAM TIGR01391 dnaG: DNA primase 5 384 5.4E-111 T 14-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 Pfam PF13662 Toprim domain 248 312 7.0E-15 T 14-10-2018 IPR006171 TOPRIM domain Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 Gene3D G3DSA:3.90.980.10 102 228 9.5E-39 T 14-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 SUPERFAMILY SSF56731 107 385 9.29E-80 T 14-10-2018 Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 Gene3D G3DSA:3.90.580.10 3 97 5.2E-35 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 Theos_1279 c63a1f7326681005d8b0f82b58dd0962 580 PIRSF PIRSF002811 2 578 2.2E-130 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 Theos_0257 67f323f4c01177b4a99fec26c7bb2404 186 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 186 31.151 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Theos_0257 67f323f4c01177b4a99fec26c7bb2404 186 SUPERFAMILY SSF52374 2 186 9.19E-50 T 14-10-2018 Theos_0257 67f323f4c01177b4a99fec26c7bb2404 186 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 5 185 5.1E-50 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Theos_0257 67f323f4c01177b4a99fec26c7bb2404 186 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 65 1.1E-12 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Theos_0257 67f323f4c01177b4a99fec26c7bb2404 186 Pfam PF01467 Cytidylyltransferase-like 5 160 2.7E-29 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Theos_0257 67f323f4c01177b4a99fec26c7bb2404 186 Gene3D G3DSA:3.40.50.620 1 186 1.8E-59 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 Gene3D G3DSA:3.40.50.10490 245 603 3.3E-144 T 14-10-2018 Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 SUPERFAMILY SSF56235 2 232 8.06E-71 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 604 41.979 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 Gene3D G3DSA:3.60.20.10 2 238 9.9E-76 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 Pfam PF01380 SIS domain 457 586 3.6E-24 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 Pfam PF01380 SIS domain 289 411 1.8E-24 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 Pfam PF13522 Glutamine amidotransferase domain 65 182 2.6E-24 T 14-10-2018 Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 604 6.0E-254 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 SUPERFAMILY SSF53697 243 604 3.9E-111 T 14-10-2018 Theos_0171 6ad35203a9356f6d6e2232e3f96623e7 604 Gene3D G3DSA:3.40.50.10490 442 589 3.3E-144 T 14-10-2018 Theos_0700 2fb4b7aa1e78d762949b21dfd7a38c9b 387 Pfam PF00999 Sodium/hydrogen exchanger family 11 377 1.6E-67 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Theos_0700 2fb4b7aa1e78d762949b21dfd7a38c9b 387 Gene3D G3DSA:1.20.1530.20 3 385 9.8E-134 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily Theos_2105 b97b287bd4d1d1f70082f86896e79cf7 352 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 6 351 2.2E-135 T 14-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form Theos_2105 b97b287bd4d1d1f70082f86896e79cf7 352 Gene3D G3DSA:3.90.550.10 3 241 1.9E-71 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_2105 b97b287bd4d1d1f70082f86896e79cf7 352 Gene3D G3DSA:2.160.10.10 242 321 1.9E-7 T 14-10-2018 Theos_2105 b97b287bd4d1d1f70082f86896e79cf7 352 Pfam PF00483 Nucleotidyl transferase 6 234 7.8E-49 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Theos_2105 b97b287bd4d1d1f70082f86896e79cf7 352 SUPERFAMILY SSF53448 5 284 3.15E-73 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 Pfam PF01645 Conserved region in glutamate synthase 788 1149 1.7E-104 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 Pfam PF00310 Glutamine amidotransferases class-II 17 380 1.2E-44 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 Gene3D G3DSA:2.160.20.60 1216 1492 1.4E-63 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 SUPERFAMILY SSF69336 1201 1488 4.05E-44 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 SUPERFAMILY SSF56235 17 387 5.25E-78 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 Gene3D G3DSA:3.20.20.70 472 1166 0.0 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 Pfam PF01493 GXGXG motif 1373 1407 4.3E-5 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 Pfam PF01493 GXGXG motif 1227 1353 4.2E-17 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 SUPERFAMILY SSF51395 459 1167 1.1E-163 T 14-10-2018 Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 Gene3D G3DSA:3.60.20.10 17 532 0.0 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 Pfam PF04898 Glutamate synthase central domain 449 725 1.4E-60 T 14-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 Theos_1674 4a37944bfcb04c82ed085352d809ca7b 1492 Gene3D G3DSA:3.20.20.70 414 772 0.0 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1495 9531e268b649cfe98aa17df513aab519 163 Gene3D G3DSA:3.30.450.30 1 138 3.2E-42 T 14-10-2018 Theos_1495 9531e268b649cfe98aa17df513aab519 163 Pfam PF03259 Roadblock/LC7 domain 17 109 1.5E-20 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain Theos_1495 9531e268b649cfe98aa17df513aab519 163 SMART SM00960 17 109 4.8E-13 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain Theos_1495 9531e268b649cfe98aa17df513aab519 163 SUPERFAMILY SSF103196 6 135 1.15E-28 T 14-10-2018 Theos_2541 b404ec8f2812af0051cb1b28d6c68b1b 524 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 274 350 1.2E-13 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal Theos_2541 b404ec8f2812af0051cb1b28d6c68b1b 524 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 19 94 6.2E-14 T 14-10-2018 IPR010094 Transposase (putative), N-terminal Theos_2101 5a31dd11df04c5063ef5c3d50db2fc8e 136 Pfam PF02590 Predicted SPOUT methyltransferase 2 135 3.4E-33 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Theos_2101 5a31dd11df04c5063ef5c3d50db2fc8e 136 SUPERFAMILY SSF75217 2 135 1.99E-34 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Theos_2101 5a31dd11df04c5063ef5c3d50db2fc8e 136 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 136 25.594 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Theos_2101 5a31dd11df04c5063ef5c3d50db2fc8e 136 Gene3D G3DSA:3.40.1280.10 1 136 8.3E-38 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Theos_2101 5a31dd11df04c5063ef5c3d50db2fc8e 136 PIRSF PIRSF004505 38 136 3.0E-29 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Theos_2101 5a31dd11df04c5063ef5c3d50db2fc8e 136 PIRSF PIRSF004505 1 44 0.0066 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Theos_1263 650fb406b8f231630a9c3f73b02d9d58 268 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 4 264 3.1E-117 T 14-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 Theos_1263 650fb406b8f231630a9c3f73b02d9d58 268 PIRSF PIRSF003092 1 268 1.9E-87 T 14-10-2018 IPR025501 ATP binding protein MinD Theos_1263 650fb406b8f231630a9c3f73b02d9d58 268 Gene3D G3DSA:3.40.50.300 3 253 3.5E-66 T 14-10-2018 Theos_1263 650fb406b8f231630a9c3f73b02d9d58 268 SUPERFAMILY SSF52540 4 248 1.48E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1263 650fb406b8f231630a9c3f73b02d9d58 268 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 221 1.6E-22 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 Pfam PF00390 Malic enzyme, N-terminal domain 89 269 5.4E-72 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 ProSitePatterns PS00331 Malic enzymes signature. 275 291 - T 14-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 Gene3D G3DSA:3.40.50.10380 23 276 1.3E-102 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 PIRSF PIRSF000106 3 573 2.9E-207 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 SUPERFAMILY SSF53223 9 278 1.22E-102 T 14-10-2018 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 PRINTS PR00072 Malic enzyme signature 95 119 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 PRINTS PR00072 Malic enzyme signature 275 291 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 PRINTS PR00072 Malic enzyme signature 191 213 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 PRINTS PR00072 Malic enzyme signature 250 268 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 PRINTS PR00072 Malic enzyme signature 415 431 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 PRINTS PR00072 Malic enzyme signature 306 322 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 PRINTS PR00072 Malic enzyme signature 155 184 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 Gene3D G3DSA:3.40.50.720 277 574 7.2E-100 T 14-10-2018 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 SMART SM01274 89 269 6.8E-97 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 SMART SM00919 279 536 3.4E-115 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 Pfam PF03949 Malic enzyme, NAD binding domain 279 535 5.7E-89 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Theos_0741 8d324ad56cc8053a72fd2efb5f29d6bc 576 SUPERFAMILY SSF51735 279 572 8.16E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1718 f6a5f974993727d15eaea0fa04469cda 204 Gene3D G3DSA:1.10.357.10 8 204 2.8E-72 T 14-10-2018 Theos_1718 f6a5f974993727d15eaea0fa04469cda 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 4.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_1718 f6a5f974993727d15eaea0fa04469cda 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 4.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_1718 f6a5f974993727d15eaea0fa04469cda 204 SUPERFAMILY SSF48498 89 203 3.19E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Theos_1718 f6a5f974993727d15eaea0fa04469cda 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 3.4E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_1718 f6a5f974993727d15eaea0fa04469cda 204 SUPERFAMILY SSF46689 8 93 5.99E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_1667 43cae1fd79b9d9b49a653f6aae819b92 207 Pfam PF00156 Phosphoribosyl transferase domain 8 191 5.8E-28 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Theos_1667 43cae1fd79b9d9b49a653f6aae819b92 207 Gene3D G3DSA:3.30.1310.20 53 113 3.5E-74 T 14-10-2018 Theos_1667 43cae1fd79b9d9b49a653f6aae819b92 207 SUPERFAMILY SSF53271 1 204 2.49E-48 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_1667 43cae1fd79b9d9b49a653f6aae819b92 207 Gene3D G3DSA:3.40.50.2020 3 200 3.5E-74 T 14-10-2018 Theos_0047 b9d049e5dd3112c048222f87de55d4a0 300 SUPERFAMILY SSF56747 11 181 1.11E-33 T 14-10-2018 Theos_0047 b9d049e5dd3112c048222f87de55d4a0 300 SMART SM00943 14 171 3.0E-44 T 14-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Theos_0047 b9d049e5dd3112c048222f87de55d4a0 300 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 14 165 2.4E-32 T 14-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 Gene3D G3DSA:3.40.140.20 371 496 3.2E-55 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 PIRSF PIRSF000414 1 496 1.4E-201 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 Pfam PF02142 MGS-like domain 12 122 5.9E-23 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 SUPERFAMILY SSF52335 2 184 4.58E-63 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 Pfam PF01808 AICARFT/IMPCHase bienzyme 128 429 1.0E-113 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 Gene3D G3DSA:3.40.50.1380 1 190 3.9E-79 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 SMART SM00798 128 431 3.7E-188 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 SMART SM00851 12 123 3.6E-50 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 SUPERFAMILY SSF53927 197 496 9.83E-122 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 Gene3D G3DSA:3.40.140.20 192 346 1.3E-60 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 496 42.537 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0942 92d4e13581d9f58e714f281b4efb3a30 496 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2 496 1.1E-188 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_2253 feb91f5cfc6e0cf85c8841c1e149295e 141 Gene3D G3DSA:2.40.10.400 39 138 1.6E-8 T 14-10-2018 Theos_0992 3481b92156a017a093dd00347db7e8f6 251 SUPERFAMILY SSF47240 8 243 4.76E-70 T 14-10-2018 IPR009078 Ferritin-like superfamily Theos_0992 3481b92156a017a093dd00347db7e8f6 251 PIRSF PIRSF037834 2 251 9.4E-92 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 Theos_0992 3481b92156a017a093dd00347db7e8f6 251 Gene3D G3DSA:1.20.1260.10 3 251 3.9E-83 T 14-10-2018 IPR012347 Ferritin-like Theos_0992 3481b92156a017a093dd00347db7e8f6 251 Pfam PF05138 Phenylacetic acid catabolic protein 3 251 6.8E-75 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 Theos_0992 3481b92156a017a093dd00347db7e8f6 251 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 16 251 1.5E-82 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 SMART SM00306 447 553 8.4E-15 T 14-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 SUPERFAMILY SSF51998 5 121 2.01E-15 T 14-10-2018 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 SUPERFAMILY SSF51998 206 1167 5.04E-113 T 14-10-2018 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Pfam PF14890 Intein splicing domain 505 854 1.3E-17 T 14-10-2018 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 PRINTS PR00379 Intein signature 605 617 3.5E-20 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 PRINTS PR00379 Intein signature 831 848 3.5E-20 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 PRINTS PR00379 Intein signature 732 747 3.5E-20 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 PRINTS PR00379 Intein signature 520 533 3.5E-20 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 PRINTS PR00379 Intein signature 700 712 3.5E-20 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 PRINTS PR00379 Intein signature 849 858 3.5E-20 T 14-10-2018 IPR006142 Intein GO:0016539 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Gene3D G3DSA:3.20.70.20 2 175 4.1E-19 T 14-10-2018 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 SUPERFAMILY SSF51294 448 854 3.92E-35 T 14-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Gene3D G3DSA:3.10.28.10 603 761 6.1E-27 T 14-10-2018 IPR027434 Homing endonuclease Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Gene3D G3DSA:2.170.16.10 451 571 1.1E-13 T 14-10-2018 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 833 855 7.4E-6 T 14-10-2018 IPR030934 Intein C-terminal splicing region Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Pfam PF02867 Ribonucleotide reductase, barrel domain 275 1155 1.4E-101 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 5 77 2.0E-9 T 14-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Gene3D G3DSA:3.20.70.20 844 1170 3.9E-109 T 14-10-2018 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 SMART SM00305 812 860 6.8E-9 T 14-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Pfam PF14528 LAGLIDADG-like domain 700 793 1.2E-17 T 14-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Pfam PF02867 Ribonucleotide reductase, barrel domain 206 273 2.2E-6 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 SUPERFAMILY SSF55608 683 758 2.85E-13 T 14-10-2018 IPR027434 Homing endonuclease Theos_0365 fc96d6605ee2b2ff52b4315e10d7e0f8 1378 Gene3D G3DSA:3.20.70.20 205 450 2.9E-50 T 14-10-2018 Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 4.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 4.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 4.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 247 7.0E-54 T 14-10-2018 Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 4 248 1.1E-97 T 14-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 Gene3D G3DSA:3.40.50.720 1 249 7.8E-78 T 14-10-2018 Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 SUPERFAMILY SSF51735 2 248 1.69E-73 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2332 80df9dfffbadbccb4cf0c44636be4b26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0482 4491e97b125db758f6852f79ae4ae1b2 227 Gene3D G3DSA:1.10.10.10 123 224 3.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0482 4491e97b125db758f6852f79ae4ae1b2 227 SMART SM00448 2 112 7.8E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0482 4491e97b125db758f6852f79ae4ae1b2 227 Pfam PF00072 Response regulator receiver domain 4 113 4.1E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_0482 4491e97b125db758f6852f79ae4ae1b2 227 Gene3D G3DSA:3.40.50.2300 1 122 2.4E-34 T 14-10-2018 Theos_0482 4491e97b125db758f6852f79ae4ae1b2 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 218 8.0E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_0482 4491e97b125db758f6852f79ae4ae1b2 227 SUPERFAMILY SSF52172 1 174 2.64E-39 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0482 4491e97b125db758f6852f79ae4ae1b2 227 SMART SM00862 143 218 1.2E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Theos_1278 9b72becf1a0a5e5dc6610448d4ce7c02 879 SUPERFAMILY SSF55073 27 188 6.12E-27 T 14-10-2018 IPR029787 Nucleotide cyclase Theos_1278 9b72becf1a0a5e5dc6610448d4ce7c02 879 Gene3D G3DSA:3.30.70.1230 25 198 9.6E-26 T 14-10-2018 IPR029787 Nucleotide cyclase Theos_1278 9b72becf1a0a5e5dc6610448d4ce7c02 879 SUPERFAMILY SSF52540 207 365 1.52E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1278 9b72becf1a0a5e5dc6610448d4ce7c02 879 Pfam PF13191 AAA ATPase domain 206 347 8.8E-8 T 14-10-2018 Theos_1278 9b72becf1a0a5e5dc6610448d4ce7c02 879 SUPERFAMILY SSF48452 461 693 5.31E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0342 addb658cdb0b770e932e597a48095db8 109 SUPERFAMILY SSF103196 4 103 9.16E-9 T 14-10-2018 Theos_0342 addb658cdb0b770e932e597a48095db8 109 SMART SM00960 3 86 5.7E-5 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain Theos_0342 addb658cdb0b770e932e597a48095db8 109 Gene3D G3DSA:3.30.450.30 3 108 1.2E-9 T 14-10-2018 Theos_0342 addb658cdb0b770e932e597a48095db8 109 Pfam PF03259 Roadblock/LC7 domain 11 82 5.6E-7 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 Gene3D G3DSA:2.40.110.10 127 238 9.2E-26 T 14-10-2018 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 Gene3D G3DSA:1.10.540.10 1 125 1.2E-36 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 PIRSF PIRSF016578 242 363 6.7E-8 T 14-10-2018 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 PIRSF PIRSF016578 3 83 1.5 T 14-10-2018 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 PIRSF PIRSF016578 135 199 0.012 T 14-10-2018 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 Gene3D G3DSA:1.20.140.10 240 382 2.3E-41 T 14-10-2018 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 4.3E-43 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 SUPERFAMILY SSF56645 1 243 1.07E-56 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 SUPERFAMILY SSF47203 229 380 1.3E-49 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 123 4.6E-21 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Theos_2455 3366e8eeb27de7cd0ecd75b6c6dde7cf 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 203 3.5E-15 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Theos_1672 a7b9793ea320f69ad253a57b7c4f356c 344 Pfam PF05673 Protein of unknown function (DUF815) 115 343 9.4E-60 T 14-10-2018 IPR008533 Domain of unknown function DUF815 Theos_1672 a7b9793ea320f69ad253a57b7c4f356c 344 SUPERFAMILY SSF52540 135 341 1.72E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1672 a7b9793ea320f69ad253a57b7c4f356c 344 SMART SM00382 159 298 0.0041 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1672 a7b9793ea320f69ad253a57b7c4f356c 344 Gene3D G3DSA:3.40.50.300 134 264 2.5E-11 T 14-10-2018 Theos_1882 82d22b365b91df512726b4e4b4380835 342 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 87 105 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 Theos_1882 82d22b365b91df512726b4e4b4380835 342 Gene3D G3DSA:1.20.120.1460 244 321 7.9E-27 T 14-10-2018 Theos_1882 82d22b365b91df512726b4e4b4380835 342 SUPERFAMILY SSF51395 4 309 2.04E-68 T 14-10-2018 Theos_1882 82d22b365b91df512726b4e4b4380835 342 PIRSF PIRSF006621 1 325 1.6E-68 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Theos_1882 82d22b365b91df512726b4e4b4380835 342 Pfam PF01207 Dihydrouridine synthase (Dus) 8 310 1.8E-69 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Theos_1882 82d22b365b91df512726b4e4b4380835 342 Gene3D G3DSA:3.20.20.70 2 243 1.7E-76 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1882 82d22b365b91df512726b4e4b4380835 342 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 315 43.487 T 14-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 Theos_2218 5d54980ff9fd6e82de15883a21278095 486 Gene3D G3DSA:3.40.50.300 255 485 2.5E-57 T 14-10-2018 Theos_2218 5d54980ff9fd6e82de15883a21278095 486 Pfam PF00005 ABC transporter 275 416 3.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2218 5d54980ff9fd6e82de15883a21278095 486 Pfam PF00005 ABC transporter 22 172 7.1E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2218 5d54980ff9fd6e82de15883a21278095 486 SUPERFAMILY SSF52540 6 242 2.3E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2218 5d54980ff9fd6e82de15883a21278095 486 ProSitePatterns PS00211 ABC transporters family signature. 389 403 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2218 5d54980ff9fd6e82de15883a21278095 486 Gene3D G3DSA:3.40.50.300 4 247 1.4E-61 T 14-10-2018 Theos_2218 5d54980ff9fd6e82de15883a21278095 486 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 220 242 2.7E-5 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Theos_2218 5d54980ff9fd6e82de15883a21278095 486 SMART SM00382 284 465 7.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2218 5d54980ff9fd6e82de15883a21278095 486 SMART SM00382 30 219 7.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2218 5d54980ff9fd6e82de15883a21278095 486 SUPERFAMILY SSF52540 258 477 6.27E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1205 b9acb55b9b5520ac7ed5da44cf4ac1bc 380 SMART SM00155 316 343 4.1E-5 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 Theos_1205 b9acb55b9b5520ac7ed5da44cf4ac1bc 380 SMART SM00155 155 182 7.1E-6 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 Theos_1205 b9acb55b9b5520ac7ed5da44cf4ac1bc 380 SUPERFAMILY SSF56024 49 210 1.57E-24 T 14-10-2018 Theos_1205 b9acb55b9b5520ac7ed5da44cf4ac1bc 380 SUPERFAMILY SSF56024 236 373 1.88E-34 T 14-10-2018 Theos_1205 b9acb55b9b5520ac7ed5da44cf4ac1bc 380 Pfam PF13091 PLD-like domain 60 206 1.2E-16 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Theos_1205 b9acb55b9b5520ac7ed5da44cf4ac1bc 380 Pfam PF13091 PLD-like domain 250 371 3.9E-26 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Theos_1205 b9acb55b9b5520ac7ed5da44cf4ac1bc 380 Gene3D G3DSA:3.30.870.10 233 373 1.4E-38 T 14-10-2018 Theos_1205 b9acb55b9b5520ac7ed5da44cf4ac1bc 380 Gene3D G3DSA:3.30.870.10 36 215 1.9E-30 T 14-10-2018 Theos_2296 428565f3692ace2497df1d106a7e28af 64 Pfam PF02597 ThiS family 9 64 2.3E-10 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Theos_2296 428565f3692ace2497df1d106a7e28af 64 SUPERFAMILY SSF54285 2 63 7.03E-15 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Theos_2296 428565f3692ace2497df1d106a7e28af 64 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 64 1.5E-14 T 14-10-2018 IPR010035 ThiS, thiamine-biosynthesis Theos_2296 428565f3692ace2497df1d106a7e28af 64 Gene3D G3DSA:3.10.20.30 1 64 4.3E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Theos_0840 1f9bcfd733918dcee5b2ca6c46b8ec1b 355 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 35 353 2.1E-78 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Theos_0840 1f9bcfd733918dcee5b2ca6c46b8ec1b 355 SUPERFAMILY SSF53383 38 353 2.66E-76 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0840 1f9bcfd733918dcee5b2ca6c46b8ec1b 355 Gene3D G3DSA:3.90.1150.10 230 355 1.2E-38 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0840 1f9bcfd733918dcee5b2ca6c46b8ec1b 355 PIRSF PIRSF001434 1 355 7.0E-100 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Theos_0840 1f9bcfd733918dcee5b2ca6c46b8ec1b 355 Gene3D G3DSA:3.40.640.10 3 229 3.1E-53 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0395 108a5ed0ad4fe607ef966759509f3fc2 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 121 1.8E-42 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Theos_0395 108a5ed0ad4fe607ef966759509f3fc2 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 310 6.5E-116 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Theos_0395 108a5ed0ad4fe607ef966759509f3fc2 310 SUPERFAMILY SSF53271 4 103 1.44E-5 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_0395 108a5ed0ad4fe607ef966759509f3fc2 310 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 309 1.0E-21 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Theos_0395 108a5ed0ad4fe607ef966759509f3fc2 310 SUPERFAMILY SSF53271 70 301 1.12E-56 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_0395 108a5ed0ad4fe607ef966759509f3fc2 310 Gene3D G3DSA:3.40.50.2020 148 286 8.6E-113 T 14-10-2018 Theos_0395 108a5ed0ad4fe607ef966759509f3fc2 310 Gene3D G3DSA:3.40.50.2020 8 300 8.6E-113 T 14-10-2018 Theos_0395 108a5ed0ad4fe607ef966759509f3fc2 310 SMART SM01400 5 121 1.1E-65 T 14-10-2018 Theos_0395 108a5ed0ad4fe607ef966759509f3fc2 310 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 5 310 43.436 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 Theos_2010 374cacc8c92ffb92aa6cffca67dd2c8d 293 SUPERFAMILY SSF52768 4 273 2.35E-72 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily Theos_2010 374cacc8c92ffb92aa6cffca67dd2c8d 293 Pfam PF00850 Histone deacetylase domain 39 273 3.0E-43 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_2010 374cacc8c92ffb92aa6cffca67dd2c8d 293 Gene3D G3DSA:3.40.800.20 3 290 3.0E-62 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_2010 374cacc8c92ffb92aa6cffca67dd2c8d 293 PRINTS PR01270 Histone deacetylase superfamily signature 110 133 1.0E-12 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_2010 374cacc8c92ffb92aa6cffca67dd2c8d 293 PRINTS PR01270 Histone deacetylase superfamily signature 144 159 1.0E-12 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_2010 374cacc8c92ffb92aa6cffca67dd2c8d 293 PRINTS PR01270 Histone deacetylase superfamily signature 217 227 1.0E-12 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Theos_1837 7f25e65a1d36a7daed1a0a47491e0a29 343 SUPERFAMILY SSF51735 138 302 1.45E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1837 7f25e65a1d36a7daed1a0a47491e0a29 343 SUPERFAMILY SSF50129 1 171 1.42E-53 T 14-10-2018 IPR011032 GroES-like superfamily Theos_1837 7f25e65a1d36a7daed1a0a47491e0a29 343 Gene3D G3DSA:3.90.180.10 15 333 5.1E-133 T 14-10-2018 Theos_1837 7f25e65a1d36a7daed1a0a47491e0a29 343 Gene3D G3DSA:3.40.50.720 148 290 5.1E-133 T 14-10-2018 Theos_1837 7f25e65a1d36a7daed1a0a47491e0a29 343 Pfam PF00107 Zinc-binding dehydrogenase 178 297 2.2E-33 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Theos_1837 7f25e65a1d36a7daed1a0a47491e0a29 343 SMART SM00829 10 340 2.5E-17 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Theos_1837 7f25e65a1d36a7daed1a0a47491e0a29 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 134 3.0E-30 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Theos_2205 e5053465a88ef35b13d15aa49fef6ae8 242 SUPERFAMILY SSF53335 25 241 1.29E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_2205 e5053465a88ef35b13d15aa49fef6ae8 242 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 30 220 4.8E-42 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Theos_2205 e5053465a88ef35b13d15aa49fef6ae8 242 Pfam PF02527 rRNA small subunit methyltransferase G 26 198 2.5E-39 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Theos_2205 e5053465a88ef35b13d15aa49fef6ae8 242 PIRSF PIRSF003078 12 224 1.6E-42 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Theos_2205 e5053465a88ef35b13d15aa49fef6ae8 242 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 19 218 25.252 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Theos_2205 e5053465a88ef35b13d15aa49fef6ae8 242 Gene3D G3DSA:3.40.50.150 2 242 2.4E-80 T 14-10-2018 Theos_1933 f84f496faf225ddeafbf3c595c606feb 281 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 2 280 1.0E-123 T 14-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 Theos_1933 f84f496faf225ddeafbf3c595c606feb 281 Gene3D G3DSA:3.30.1490.20 104 172 4.9E-30 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Theos_1933 f84f496faf225ddeafbf3c595c606feb 281 Gene3D G3DSA:3.30.470.80 173 281 1.6E-41 T 14-10-2018 Theos_1933 f84f496faf225ddeafbf3c595c606feb 281 Pfam PF08443 RimK-like ATP-grasp domain 88 274 5.5E-31 T 14-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 Theos_1933 f84f496faf225ddeafbf3c595c606feb 281 SUPERFAMILY SSF56059 89 276 1.01E-47 T 14-10-2018 Theos_1933 f84f496faf225ddeafbf3c595c606feb 281 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 275 1.5E-107 T 14-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 Theos_1933 f84f496faf225ddeafbf3c595c606feb 281 SUPERFAMILY SSF52440 1 88 8.34E-23 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Theos_1933 f84f496faf225ddeafbf3c595c606feb 281 Gene3D G3DSA:3.40.50.20 1 102 7.3E-32 T 14-10-2018 Theos_1724 adafbdaa922801ef1663c62f1f19e3d7 382 SMART SM00567 E-Z type HEAT repeats 306 335 660.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Theos_1724 adafbdaa922801ef1663c62f1f19e3d7 382 SMART SM00567 E-Z type HEAT repeats 337 362 0.45 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Theos_1724 adafbdaa922801ef1663c62f1f19e3d7 382 SMART SM00567 E-Z type HEAT repeats 151 180 16.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Theos_1724 adafbdaa922801ef1663c62f1f19e3d7 382 Gene3D G3DSA:1.25.10.10 107 288 1.2E-6 T 14-10-2018 IPR011989 Armadillo-like helical Theos_1724 adafbdaa922801ef1663c62f1f19e3d7 382 Gene3D G3DSA:1.25.10.110 294 377 2.5E-7 T 14-10-2018 Theos_1724 adafbdaa922801ef1663c62f1f19e3d7 382 SUPERFAMILY SSF48371 45 377 6.1E-16 T 14-10-2018 IPR016024 Armadillo-type fold Theos_1724 adafbdaa922801ef1663c62f1f19e3d7 382 Pfam PF13646 HEAT repeats 300 375 2.3E-8 T 14-10-2018 Theos_0656 dd7dd25af4cef1d1515b7577e4c19839 204 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 177 23.413 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Theos_0656 dd7dd25af4cef1d1515b7577e4c19839 204 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 94 176 1.4E-28 T 14-10-2018 IPR020057 Ribosomal protein L25, beta domain Theos_0656 dd7dd25af4cef1d1515b7577e4c19839 204 Pfam PF01386 Ribosomal L25p family 5 87 2.4E-12 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Theos_0656 dd7dd25af4cef1d1515b7577e4c19839 204 SUPERFAMILY SSF50715 1 181 7.15E-50 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_0656 dd7dd25af4cef1d1515b7577e4c19839 204 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 17 87 7.0E-30 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Theos_0656 dd7dd25af4cef1d1515b7577e4c19839 204 Gene3D G3DSA:2.170.120.20 91 184 1.7E-34 T 14-10-2018 IPR037121 Ribosomal protein L25, C-terminal Theos_0656 dd7dd25af4cef1d1515b7577e4c19839 204 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 17 174 4.8E-40 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Theos_0656 dd7dd25af4cef1d1515b7577e4c19839 204 Gene3D G3DSA:2.40.240.10 1 90 4.8E-32 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 392 535 1.2E-14 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 SUPERFAMILY SSF55124 13 117 4.58E-25 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 SUPERFAMILY SSF56014 395 552 1.44E-37 T 14-10-2018 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 47 107 1.2E-17 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 318 383 1.3E-16 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 Gene3D G3DSA:3.30.413.10 117 301 6.9E-90 T 14-10-2018 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 118 267 1.5E-39 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 PRINTS PR00397 Sirohaem Fe-binding site signature 394 412 9.9E-7 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 PRINTS PR00397 Sirohaem Fe-binding site signature 442 460 9.9E-7 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 Gene3D G3DSA:3.90.480.10 50 371 6.9E-90 T 14-10-2018 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 Gene3D G3DSA:3.30.413.10 389 565 9.3E-44 T 14-10-2018 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 442 458 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 SUPERFAMILY SSF56014 118 273 2.22E-43 T 14-10-2018 Theos_2298 54edc2650d4d5039e5c77b4d3abc72c1 574 SUPERFAMILY SSF55124 249 405 3.11E-19 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Theos_1940 70a98036c744b030ebfc0dbd9b9211bd 376 SUPERFAMILY SSF51569 2 282 5.13E-66 T 14-10-2018 Theos_1940 70a98036c744b030ebfc0dbd9b9211bd 376 Pfam PF00682 HMGL-like 5 265 1.8E-67 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Theos_1940 70a98036c744b030ebfc0dbd9b9211bd 376 Gene3D G3DSA:3.20.20.70 1 271 2.2E-109 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1940 70a98036c744b030ebfc0dbd9b9211bd 376 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 192 205 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_1940 70a98036c744b030ebfc0dbd9b9211bd 376 Gene3D G3DSA:1.10.238.260 272 376 8.0E-34 T 14-10-2018 Theos_1940 70a98036c744b030ebfc0dbd9b9211bd 376 TIGRFAM TIGR02146 LysS_fung_arch: homocitrate synthase 6 354 1.4E-161 T 14-10-2018 IPR011872 Homocitrate synthase, fungi/archaea GO:0004410|GO:0019752|GO:0019878|GO:0046912 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 Theos_1940 70a98036c744b030ebfc0dbd9b9211bd 376 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Theos_0279 e2efd75cadf6ccb9a6ddd5b31900406a 96 Gene3D G3DSA:3.30.70.330 1 96 1.2E-37 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Theos_0279 e2efd75cadf6ccb9a6ddd5b31900406a 96 Pfam PF00276 Ribosomal protein L23 6 90 4.0E-31 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Theos_0279 e2efd75cadf6ccb9a6ddd5b31900406a 96 SUPERFAMILY SSF54189 3 92 1.15E-31 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0279 e2efd75cadf6ccb9a6ddd5b31900406a 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 94 22.098 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Theos_1357 c811887cf4483986dc3ed63d199133b3 282 Gene3D G3DSA:1.10.357.140 10 161 4.8E-51 T 14-10-2018 Theos_1357 c811887cf4483986dc3ed63d199133b3 282 Pfam PF01040 UbiA prenyltransferase family 20 262 4.9E-51 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 Theos_1357 c811887cf4483986dc3ed63d199133b3 282 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 3 280 8.6E-101 T 14-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related Theos_1357 c811887cf4483986dc3ed63d199133b3 282 Gene3D G3DSA:1.20.120.1780 162 282 2.4E-33 T 14-10-2018 Theos_2212 b84058ebf93cfc8c491fec901cfe29f2 494 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 9 426 4.5E-100 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane Theos_0092 1acffe3326e74f5debfc26b7bdc494fa 211 Pfam PF08241 Methyltransferase domain 42 136 4.2E-16 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Theos_0092 1acffe3326e74f5debfc26b7bdc494fa 211 Gene3D G3DSA:3.40.50.150 4 192 2.7E-27 T 14-10-2018 Theos_0092 1acffe3326e74f5debfc26b7bdc494fa 211 SUPERFAMILY SSF53335 14 176 4.03E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1990 717ec14a9009f08aa4e9fb2a1f476817 133 Gene3D G3DSA:3.10.129.10 1 132 2.1E-43 T 14-10-2018 Theos_1990 717ec14a9009f08aa4e9fb2a1f476817 133 SUPERFAMILY SSF54637 1 127 4.94E-40 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_1990 717ec14a9009f08aa4e9fb2a1f476817 133 Pfam PF13279 Thioesterase-like superfamily 12 124 1.4E-18 T 14-10-2018 Theos_1366 7017fb826d2f1534145be663d4c9ed67 292 SUPERFAMILY SSF56317 4 280 4.71E-25 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Theos_1366 7017fb826d2f1534145be663d4c9ed67 292 Gene3D G3DSA:3.60.110.10 37 284 1.1E-20 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Theos_1366 7017fb826d2f1534145be663d4c9ed67 292 Pfam PF00795 Carbon-nitrogen hydrolase 43 201 3.7E-6 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 SUPERFAMILY SSF56300 27 321 7.37E-88 T 14-10-2018 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 Gene3D G3DSA:3.60.21.10 27 331 6.1E-125 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 Pfam PF00149 Calcineurin-like phosphoesterase 30 240 3.5E-10 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 Pfam PF02872 5'-nucleotidase, C-terminal domain 332 492 6.7E-52 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 ProSitePatterns PS00786 5'-nucleotidase signature 2. 107 118 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 SUPERFAMILY SSF55816 329 531 4.19E-71 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 PRINTS PR01607 Apyrase family signature 466 485 9.1E-39 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 PRINTS PR01607 Apyrase family signature 27 45 9.1E-39 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 PRINTS PR01607 Apyrase family signature 389 412 9.1E-39 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 PRINTS PR01607 Apyrase family signature 223 246 9.1E-39 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 PRINTS PR01607 Apyrase family signature 204 221 9.1E-39 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 PRINTS PR01607 Apyrase family signature 268 288 9.1E-39 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 ProSitePatterns PS00785 5'-nucleotidase signature 1. 29 41 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_0516 af315269ae3ce2bc4eeed313dddbe879 551 Gene3D G3DSA:3.90.780.10 332 533 8.0E-90 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_1230 84bebef8d4ef52b3ca755c5dde5e5c67 170 Gene3D G3DSA:3.30.70.1150 82 163 3.6E-30 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Theos_1230 84bebef8d4ef52b3ca755c5dde5e5c67 170 Pfam PF10369 Small subunit of acetolactate synthase 83 157 2.3E-28 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Theos_1230 84bebef8d4ef52b3ca755c5dde5e5c67 170 Gene3D G3DSA:3.30.70.260 1 78 4.5E-33 T 14-10-2018 Theos_1230 84bebef8d4ef52b3ca755c5dde5e5c67 170 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 158 1.6E-59 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Theos_1230 84bebef8d4ef52b3ca755c5dde5e5c67 170 SUPERFAMILY SSF55021 2 76 2.99E-20 T 14-10-2018 Theos_1230 84bebef8d4ef52b3ca755c5dde5e5c67 170 Pfam PF13710 ACT domain 12 73 2.5E-15 T 14-10-2018 Theos_1230 84bebef8d4ef52b3ca755c5dde5e5c67 170 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 75 2.0E-33 T 14-10-2018 Theos_1230 84bebef8d4ef52b3ca755c5dde5e5c67 170 SUPERFAMILY SSF55021 78 162 4.23E-27 T 14-10-2018 Theos_2293 38937f73115b44add0f8d2b91347f905 435 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 9.5E-183 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Theos_2293 38937f73115b44add0f8d2b91347f905 435 Gene3D G3DSA:3.20.20.540 46 363 4.6E-137 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Theos_2293 38937f73115b44add0f8d2b91347f905 435 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 426 89.469 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Theos_2293 38937f73115b44add0f8d2b91347f905 435 Pfam PF01964 Radical SAM ThiC family 2 421 1.6E-187 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Theos_2350 ff2a1181a944a8564c2d9994196fa231 323 Gene3D G3DSA:1.10.620.20 2 294 5.3E-44 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 Theos_2350 ff2a1181a944a8564c2d9994196fa231 323 Pfam PF00268 Ribonucleotide reductase, small chain 9 279 2.2E-31 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_2350 ff2a1181a944a8564c2d9994196fa231 323 SUPERFAMILY SSF47240 9 323 4.72E-46 T 14-10-2018 IPR009078 Ferritin-like superfamily Theos_0735 aaca7df8b7b18f00ffff166c907ab1cd 164 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.173 T 14-10-2018 IPR033747 Class I PurE Theos_0735 aaca7df8b7b18f00ffff166c907ab1cd 164 SMART SM01001 3 154 1.6E-101 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Theos_0735 aaca7df8b7b18f00ffff166c907ab1cd 164 Gene3D G3DSA:3.40.50.7700 1 164 7.4E-74 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Theos_0735 aaca7df8b7b18f00ffff166c907ab1cd 164 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 158 2.7E-67 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Theos_0735 aaca7df8b7b18f00ffff166c907ab1cd 164 PIRSF PIRSF001338 1 163 6.8E-67 T 14-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 Theos_0735 aaca7df8b7b18f00ffff166c907ab1cd 164 SUPERFAMILY SSF52255 4 162 1.83E-66 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Theos_0735 aaca7df8b7b18f00ffff166c907ab1cd 164 Pfam PF00731 AIR carboxylase 5 152 1.1E-65 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Theos_0258 08c95de7120184d34e05f878d9dd27a4 181 Pfam PF01966 HD domain 22 114 5.0E-11 T 14-10-2018 IPR006674 HD domain Theos_0258 08c95de7120184d34e05f878d9dd27a4 181 SMART SM00471 18 141 7.9E-8 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0258 08c95de7120184d34e05f878d9dd27a4 181 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 15 177 2.0E-29 T 14-10-2018 IPR005249 Conserved hypothetical protein CHP00488 Theos_0258 08c95de7120184d34e05f878d9dd27a4 181 Gene3D G3DSA:1.10.3210.10 3 181 4.3E-38 T 14-10-2018 Theos_0258 08c95de7120184d34e05f878d9dd27a4 181 SUPERFAMILY SSF109604 15 176 1.62E-23 T 14-10-2018 Theos_1925 e032a21ce930f7506da0271cfce8eebb 323 Pfam PF00633 Helix-hairpin-helix motif 95 117 1.8E-6 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 Theos_1925 e032a21ce930f7506da0271cfce8eebb 323 Gene3D G3DSA:1.10.340.30 16 122 2.5E-74 T 14-10-2018 Theos_1925 e032a21ce930f7506da0271cfce8eebb 323 Gene3D G3DSA:1.10.1670.10 5 196 2.5E-74 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Theos_1925 e032a21ce930f7506da0271cfce8eebb 323 SUPERFAMILY SSF55811 205 292 9.53E-5 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Theos_1925 e032a21ce930f7506da0271cfce8eebb 323 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 31 158 7.4E-18 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Theos_1925 e032a21ce930f7506da0271cfce8eebb 323 SUPERFAMILY SSF48150 2 197 1.35E-66 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Theos_1925 e032a21ce930f7506da0271cfce8eebb 323 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 178 194 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 Theos_1925 e032a21ce930f7506da0271cfce8eebb 323 SMART SM00478 34 176 3.0E-44 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Theos_0277 9681284b9c4756ac74bf50fd99b44d99 206 ProSitePatterns PS00474 Ribosomal protein L3 signature. 96 119 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site Theos_0277 9681284b9c4756ac74bf50fd99b44d99 206 SUPERFAMILY SSF50447 2 203 1.32E-75 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_0277 9681284b9c4756ac74bf50fd99b44d99 206 Pfam PF00297 Ribosomal protein L3 87 175 1.2E-14 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0277 9681284b9c4756ac74bf50fd99b44d99 206 Gene3D G3DSA:2.40.30.10 126 205 1.0E-16 T 14-10-2018 Theos_0277 9681284b9c4756ac74bf50fd99b44d99 206 Gene3D G3DSA:2.40.50.620 30 91 9.2E-18 T 14-10-2018 Theos_0277 9681284b9c4756ac74bf50fd99b44d99 206 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 199 1.7E-83 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0277 9681284b9c4756ac74bf50fd99b44d99 206 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 202 37.99 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0501 917c9dff503cecbc8028afffe97fba69 272 Gene3D G3DSA:3.40.50.720 4 258 2.3E-94 T 14-10-2018 Theos_0501 917c9dff503cecbc8028afffe97fba69 272 SUPERFAMILY SSF69572 2 266 8.24E-97 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 Theos_0501 917c9dff503cecbc8028afffe97fba69 272 Pfam PF00899 ThiF family 11 248 1.5E-67 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Theos_0674 1f6309d9451c68b61263e362663bcafa 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 6 59 1.2E-25 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0674 1f6309d9451c68b61263e362663bcafa 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 58 20.393 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0674 1f6309d9451c68b61263e362663bcafa 60 Pfam PF01783 Ribosomal L32p protein family 5 59 4.6E-27 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0674 1f6309d9451c68b61263e362663bcafa 60 SUPERFAMILY SSF57829 5 60 6.71E-22 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Theos_0728 b8640bdceaabf81266914cd69ab9b420 205 Gene3D G3DSA:3.40.109.10 5 204 2.1E-63 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Theos_0728 b8640bdceaabf81266914cd69ab9b420 205 Pfam PF00881 Nitroreductase family 15 185 1.2E-28 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Theos_0728 b8640bdceaabf81266914cd69ab9b420 205 SUPERFAMILY SSF55469 9 203 1.31E-59 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Theos_0745 38cfebd59867138b82b149323181fd93 128 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.542 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 Theos_0745 38cfebd59867138b82b149323181fd93 128 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 126 1.1E-49 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 Theos_0745 38cfebd59867138b82b149323181fd93 128 SUPERFAMILY SSF51230 3 125 5.23E-49 T 14-10-2018 IPR011053 Single hybrid motif Theos_0745 38cfebd59867138b82b149323181fd93 128 Pfam PF01597 Glycine cleavage H-protein 8 125 4.5E-46 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate Theos_0745 38cfebd59867138b82b149323181fd93 128 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Theos_0745 38cfebd59867138b82b149323181fd93 128 Gene3D G3DSA:2.40.50.100 1 128 4.8E-56 T 14-10-2018 Theos_2140 59b8962cab589a05974d598b3d423af1 401 Gene3D G3DSA:1.20.1250.20 201 401 1.2E-21 T 14-10-2018 Theos_2140 59b8962cab589a05974d598b3d423af1 401 ProSitePatterns PS00216 Sugar transport proteins signature 1. 271 288 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Theos_2140 59b8962cab589a05974d598b3d423af1 401 Pfam PF13347 MFS/sugar transport protein 42 334 2.1E-18 T 14-10-2018 Theos_2140 59b8962cab589a05974d598b3d423af1 401 Gene3D G3DSA:1.20.1250.20 9 190 1.7E-18 T 14-10-2018 Theos_2140 59b8962cab589a05974d598b3d423af1 401 SUPERFAMILY SSF103473 10 399 3.66E-45 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1453 961998b54f24739b10241157be9d3c3f 482 Gene3D G3DSA:3.40.50.720 2 245 7.2E-39 T 14-10-2018 Theos_1453 961998b54f24739b10241157be9d3c3f 482 Pfam PF13460 NAD(P)H-binding 7 113 5.2E-15 T 14-10-2018 IPR016040 NAD(P)-binding domain Theos_1453 961998b54f24739b10241157be9d3c3f 482 SUPERFAMILY SSF55961 325 468 5.5E-10 T 14-10-2018 Theos_1453 961998b54f24739b10241157be9d3c3f 482 SUPERFAMILY SSF51735 1 288 1.43E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1453 961998b54f24739b10241157be9d3c3f 482 Pfam PF11066 Protein of unknown function (DUF2867) 323 457 2.7E-28 T 14-10-2018 IPR021295 Protein of unknown function DUF2867 Theos_1926 aa1330b2b303d769876ff78682995792 136 Gene3D G3DSA:3.40.50.720 1 135 2.5E-32 T 14-10-2018 Theos_1926 aa1330b2b303d769876ff78682995792 136 SUPERFAMILY SSF51735 5 133 3.25E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1926 aa1330b2b303d769876ff78682995792 136 Pfam PF13380 CoA binding domain 14 130 6.4E-31 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Theos_1926 aa1330b2b303d769876ff78682995792 136 SMART SM00881 10 104 9.3E-10 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 PIRSF PIRSF000185 13 419 8.2E-145 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 99 113 5.0E-22 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 344 355 5.0E-22 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 221 241 5.0E-22 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 179 201 5.0E-22 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 188 416 2.1E-51 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 Gene3D G3DSA:1.10.8.1210 6 39 1.4E-92 T 14-10-2018 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 SMART SM00839 190 416 4.5E-57 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 Gene3D G3DSA:3.40.50.720 188 419 1.2E-61 T 14-10-2018 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 SUPERFAMILY SSF53223 13 190 1.5E-64 T 14-10-2018 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 42 170 1.7E-48 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 SUPERFAMILY SSF51735 188 418 1.63E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0626 ff3fb3ddd9b620b681e3c900726ebd1a 419 Gene3D G3DSA:3.40.50.10860 40 175 1.4E-92 T 14-10-2018 Theos_1478 cf77b2079422ad0b1902a8171cd96ba5 315 Gene3D G3DSA:3.40.50.1820 97 314 3.6E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1478 cf77b2079422ad0b1902a8171cd96ba5 315 SUPERFAMILY SSF53474 109 312 4.57E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1478 cf77b2079422ad0b1902a8171cd96ba5 315 Pfam PF00756 Putative esterase 124 310 1.1E-21 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 SUPERFAMILY SSF55821 6 202 1.44E-82 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 Gene3D G3DSA:3.90.870.10 1 204 1.8E-86 T 14-10-2018 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 7 199 8.0E-70 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 SUPERFAMILY SSF142695 206 375 3.92E-75 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 205 399 42.693 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 3 396 54.033 T 14-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 PIRSF PIRSF001259 2 399 5.0E-175 T 14-10-2018 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 209 397 8.7E-83 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 203 38.239 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 9 197 6.1E-84 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 Gene3D G3DSA:3.40.50.10990 206 378 1.1E-77 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Theos_1164 8d70d64a90833e12fae0b6a458845bd1 399 Pfam PF00925 GTP cyclohydrolase II 209 374 2.1E-76 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Theos_0266 012822220880574c51c8c8515111c0c4 423 Gene3D G3DSA:3.40.1030.10 78 323 4.4E-140 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 SMART SM00941 337 410 2.4E-26 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 SUPERFAMILY SSF54680 329 420 1.96E-23 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 109 124 - T 14-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 Gene3D G3DSA:1.20.970.10 1 67 1.1E-21 T 14-10-2018 Theos_0266 012822220880574c51c8c8515111c0c4 423 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 66 7.8E-17 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 PIRSF PIRSF000478 1 422 1.2E-146 T 14-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 6 406 7.8E-158 T 14-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 337 408 8.3E-21 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 SUPERFAMILY SSF52418 76 320 1.3E-80 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 SUPERFAMILY SSF47648 2 69 7.98E-16 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 Gene3D G3DSA:3.90.1170.30 324 408 4.4E-140 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0266 012822220880574c51c8c8515111c0c4 423 Pfam PF00591 Glycosyl transferase family, a/b domain 77 283 7.1E-34 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Theos_0060 6cef5c3f256e987c75d7e620ec926211 177 Gene3D G3DSA:2.60.40.4070 91 145 4.4E-8 T 14-10-2018 Theos_0060 6cef5c3f256e987c75d7e620ec926211 177 Pfam PF10029 Predicted periplasmic protein (DUF2271) 41 166 2.5E-30 T 14-10-2018 IPR014469 Protein of unknown function DUF2271 Theos_0060 6cef5c3f256e987c75d7e620ec926211 177 PIRSF PIRSF014995 10 177 3.1E-33 T 14-10-2018 IPR014469 Protein of unknown function DUF2271 Theos_2267 8a3c514fdc64b767f6f4878bc610a5b6 831 Pfam PF13361 UvrD-like helicase C-terminal domain 408 572 7.6E-11 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Theos_2267 8a3c514fdc64b767f6f4878bc610a5b6 831 Pfam PF13361 UvrD-like helicase C-terminal domain 683 781 4.4E-14 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Theos_2267 8a3c514fdc64b767f6f4878bc610a5b6 831 Gene3D G3DSA:3.40.50.300 1 141 3.6E-38 T 14-10-2018 Theos_2267 8a3c514fdc64b767f6f4878bc610a5b6 831 Gene3D G3DSA:3.40.50.300 295 429 1.5E-31 T 14-10-2018 Theos_2267 8a3c514fdc64b767f6f4878bc610a5b6 831 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 395 2.2E-57 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Theos_2267 8a3c514fdc64b767f6f4878bc610a5b6 831 SUPERFAMILY SSF52540 2 785 5.8E-111 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2267 8a3c514fdc64b767f6f4878bc610a5b6 831 Gene3D G3DSA:3.40.50.300 467 566 1.4E-17 T 14-10-2018 Theos_2267 8a3c514fdc64b767f6f4878bc610a5b6 831 Gene3D G3DSA:3.40.50.300 668 802 2.2E-19 T 14-10-2018 Theos_1463 b1083173af558147c3d2e69477183e91 405 SUPERFAMILY SSF54106 114 159 2.49E-7 T 14-10-2018 Theos_1463 b1083173af558147c3d2e69477183e91 405 SMART SM00257 54 97 8.0E-9 T 14-10-2018 IPR018392 LysM domain Theos_1463 b1083173af558147c3d2e69477183e91 405 SMART SM00257 166 210 0.17 T 14-10-2018 IPR018392 LysM domain Theos_1463 b1083173af558147c3d2e69477183e91 405 SMART SM00257 114 159 6.6E-8 T 14-10-2018 IPR018392 LysM domain Theos_1463 b1083173af558147c3d2e69477183e91 405 Gene3D G3DSA:3.10.350.10 41 104 4.5E-14 T 14-10-2018 IPR036779 LysM domain superfamily Theos_1463 b1083173af558147c3d2e69477183e91 405 Gene3D G3DSA:3.10.350.10 167 220 1.9E-5 T 14-10-2018 IPR036779 LysM domain superfamily Theos_1463 b1083173af558147c3d2e69477183e91 405 Pfam PF01476 LysM domain 171 207 1.0E-5 T 14-10-2018 IPR018392 LysM domain Theos_1463 b1083173af558147c3d2e69477183e91 405 Pfam PF01476 LysM domain 115 159 1.5E-8 T 14-10-2018 IPR018392 LysM domain Theos_1463 b1083173af558147c3d2e69477183e91 405 Pfam PF01476 LysM domain 55 97 3.4E-10 T 14-10-2018 IPR018392 LysM domain Theos_1463 b1083173af558147c3d2e69477183e91 405 Pfam PF01551 Peptidase family M23 305 400 2.9E-34 T 14-10-2018 IPR016047 Peptidase M23 Theos_1463 b1083173af558147c3d2e69477183e91 405 SUPERFAMILY SSF54106 52 97 3.92E-9 T 14-10-2018 Theos_1463 b1083173af558147c3d2e69477183e91 405 SUPERFAMILY SSF51261 224 404 6.8E-58 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_1463 b1083173af558147c3d2e69477183e91 405 Gene3D G3DSA:3.10.350.10 111 159 2.6E-11 T 14-10-2018 IPR036779 LysM domain superfamily Theos_1463 b1083173af558147c3d2e69477183e91 405 Gene3D G3DSA:2.70.70.10 248 405 1.4E-49 T 14-10-2018 IPR011055 Duplicated hybrid motif Theos_0152 c4f59c3a2928734731d1a1387cf19a7b 202 Gene3D G3DSA:3.30.1130.10 72 202 3.5E-64 T 14-10-2018 Theos_0152 c4f59c3a2928734731d1a1387cf19a7b 202 SUPERFAMILY SSF55620 15 201 3.41E-79 T 14-10-2018 Theos_0152 c4f59c3a2928734731d1a1387cf19a7b 202 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 81 97 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Theos_0152 c4f59c3a2928734731d1a1387cf19a7b 202 Pfam PF01227 GTP cyclohydrolase I 28 201 4.6E-76 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Theos_0152 c4f59c3a2928734731d1a1387cf19a7b 202 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 29 202 9.9E-79 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Theos_0152 c4f59c3a2928734731d1a1387cf19a7b 202 Gene3D G3DSA:1.10.286.10 18 71 1.4E-24 T 14-10-2018 Theos_0152 c4f59c3a2928734731d1a1387cf19a7b 202 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 20 202 38.955 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Theos_1093 f8f7b5b57515170fe0b91b1f53a00c6c 300 Gene3D G3DSA:3.40.50.720 110 267 3.0E-91 T 14-10-2018 Theos_1093 f8f7b5b57515170fe0b91b1f53a00c6c 300 SUPERFAMILY SSF50129 1 129 1.98E-32 T 14-10-2018 IPR011032 GroES-like superfamily Theos_1093 f8f7b5b57515170fe0b91b1f53a00c6c 300 SMART SM00829 10 297 2.4E-14 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Theos_1093 f8f7b5b57515170fe0b91b1f53a00c6c 300 Gene3D G3DSA:3.90.180.10 16 296 3.0E-91 T 14-10-2018 Theos_1093 f8f7b5b57515170fe0b91b1f53a00c6c 300 Pfam PF00107 Zinc-binding dehydrogenase 135 251 1.3E-23 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Theos_1093 f8f7b5b57515170fe0b91b1f53a00c6c 300 SUPERFAMILY SSF51735 99 253 1.15E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2468 b100e787fd36fa7a20eed5097a2a766d 58 Gene3D G3DSA:3.30.429.10 2 48 8.9E-11 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily Theos_0137 010e813e71d56bf47cd07b1f029a2331 120 SUPERFAMILY SSF54593 5 118 1.98E-7 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_1639 da4516b526fabbf39d0c1d5c0064d058 132 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 127 10.897 T 14-10-2018 IPR022907 VapC family GO:0004540 Theos_1639 da4516b526fabbf39d0c1d5c0064d058 132 SUPERFAMILY SSF88723 3 126 2.33E-16 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_1639 da4516b526fabbf39d0c1d5c0064d058 132 Pfam PF01850 PIN domain 5 120 4.2E-10 T 14-10-2018 IPR002716 PIN domain Theos_1639 da4516b526fabbf39d0c1d5c0064d058 132 Gene3D G3DSA:3.40.50.1010 3 123 5.1E-27 T 14-10-2018 Theos_1242 bd237149ac9b5009af909ba977cb4335 99 Gene3D G3DSA:3.30.460.10 6 95 7.5E-26 T 14-10-2018 Theos_1242 bd237149ac9b5009af909ba977cb4335 99 SUPERFAMILY SSF81301 8 96 8.94E-24 T 14-10-2018 Theos_1242 bd237149ac9b5009af909ba977cb4335 99 Pfam PF01909 Nucleotidyltransferase domain 10 92 7.4E-12 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 PIRSF PIRSF000729 4 367 7.0E-129 T 14-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 TIGRFAM TIGR01027 proB: glutamate 5-kinase 8 364 2.0E-133 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 SUPERFAMILY SSF53633 8 255 2.49E-64 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 Gene3D G3DSA:2.30.130.10 264 366 1.5E-34 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 14-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 Hamap MF_00456 Glutamate 5-kinase [proB]. 8 258 36.825 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 SUPERFAMILY SSF88697 275 365 7.18E-25 T 14-10-2018 IPR015947 PUA-like superfamily Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 SMART SM00359 275 358 6.6E-27 T 14-10-2018 IPR002478 PUA domain GO:0003723 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 Pfam PF01472 PUA domain 275 349 2.0E-24 T 14-10-2018 IPR002478 PUA domain GO:0003723 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 Gene3D G3DSA:3.40.1160.10 4 262 1.5E-82 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 Pfam PF00696 Amino acid kinase family 8 231 2.7E-40 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 PRINTS PR00474 Glutamate 5-kinase family signature 149 176 1.0E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 PRINTS PR00474 Glutamate 5-kinase family signature 77 105 1.0E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 PRINTS PR00474 Glutamate 5-kinase family signature 117 138 1.0E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 1.0E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_2037 d4d116b7e02d253fd5622a702af5073e 369 PRINTS PR00474 Glutamate 5-kinase family signature 44 58 1.0E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Theos_2208 30eb327205751e0e96a62f4d30973d34 135 SUPERFAMILY SSF69118 9 128 1.46E-16 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Theos_2208 30eb327205751e0e96a62f4d30973d34 135 Pfam PF02627 Carboxymuconolactone decarboxylase family 43 124 2.4E-6 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Theos_2208 30eb327205751e0e96a62f4d30973d34 135 Gene3D G3DSA:1.20.1290.10 8 134 8.4E-26 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Theos_0744 182083c2bc095e35100649dde9a77c0a 349 Gene3D G3DSA:4.10.1250.10 232 269 1.4E-9 T 14-10-2018 Theos_0744 182083c2bc095e35100649dde9a77c0a 349 Gene3D G3DSA:2.40.30.110 271 348 1.3E-20 T 14-10-2018 Theos_0744 182083c2bc095e35100649dde9a77c0a 349 Gene3D G3DSA:3.30.1360.120 4 230 1.3E-89 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Theos_0744 182083c2bc095e35100649dde9a77c0a 349 SUPERFAMILY SSF101790 268 347 6.05E-20 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal Theos_0744 182083c2bc095e35100649dde9a77c0a 349 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 259 341 1.1E-15 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Theos_0744 182083c2bc095e35100649dde9a77c0a 349 SUPERFAMILY SSF103025 1 267 1.73E-96 T 14-10-2018 Theos_0744 182083c2bc095e35100649dde9a77c0a 349 Pfam PF01571 Aminomethyltransferase folate-binding domain 6 253 7.4E-91 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain Theos_0744 182083c2bc095e35100649dde9a77c0a 349 PIRSF PIRSF006487 1 349 1.3E-83 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Theos_0744 182083c2bc095e35100649dde9a77c0a 349 Gene3D G3DSA:3.30.70.1400 50 136 1.3E-89 T 14-10-2018 Theos_0744 182083c2bc095e35100649dde9a77c0a 349 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 348 40.428 T 14-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Theos_0744 182083c2bc095e35100649dde9a77c0a 349 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 347 1.9E-108 T 14-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Theos_1259 c7d6fca1a2a3ce7acea867092845fd92 286 SUPERFAMILY SSF161098 15 276 6.67E-48 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1259 c7d6fca1a2a3ce7acea867092845fd92 286 Gene3D G3DSA:1.10.3720.10 7 284 1.9E-48 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1259 c7d6fca1a2a3ce7acea867092845fd92 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 275 6.7E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0550 9de55bd1f01fe1d193bf25690f4bc987 158 SUPERFAMILY SSF52980 12 156 1.88E-21 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_0550 9de55bd1f01fe1d193bf25690f4bc987 158 Gene3D G3DSA:3.90.1570.10 1 158 1.5E-13 T 14-10-2018 Theos_0550 9de55bd1f01fe1d193bf25690f4bc987 158 Pfam PF05685 Putative restriction endonuclease 9 137 4.7E-16 T 14-10-2018 IPR008538 Domain of unknown function DUF820 Theos_0017 1714a7cec904d28c40b732a2c73ae6a0 165 Gene3D G3DSA:3.40.50.880 2 165 4.7E-43 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_0017 1714a7cec904d28c40b732a2c73ae6a0 165 Pfam PF01965 DJ-1/PfpI family 5 161 4.0E-41 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 Theos_0017 1714a7cec904d28c40b732a2c73ae6a0 165 SUPERFAMILY SSF52317 4 164 1.36E-42 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_2304 3ec74a6e51f941b35be4e1591437b77d 352 Pfam PF14306 PUA-like domain 7 131 2.0E-34 T 14-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 Theos_2304 3ec74a6e51f941b35be4e1591437b77d 352 Pfam PF01747 ATP-sulfurylase 139 345 5.3E-78 T 14-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 Theos_2304 3ec74a6e51f941b35be4e1591437b77d 352 Gene3D G3DSA:3.10.400.10 5 135 1.0E-42 T 14-10-2018 Theos_2304 3ec74a6e51f941b35be4e1591437b77d 352 Gene3D G3DSA:3.40.50.620 136 348 1.7E-89 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_2304 3ec74a6e51f941b35be4e1591437b77d 352 SUPERFAMILY SSF88697 6 133 3.08E-35 T 14-10-2018 IPR015947 PUA-like superfamily Theos_2304 3ec74a6e51f941b35be4e1591437b77d 352 SUPERFAMILY SSF52374 139 345 6.57E-70 T 14-10-2018 Theos_0957 1ba1d246af66d3697c4ded05463f48a4 283 Gene3D G3DSA:3.40.50.10170 8 153 3.2E-35 T 14-10-2018 Theos_0957 1ba1d246af66d3697c4ded05463f48a4 283 Pfam PF02645 Uncharacterised protein, DegV family COG1307 9 279 8.7E-61 T 14-10-2018 IPR003797 DegV Theos_0957 1ba1d246af66d3697c4ded05463f48a4 283 SUPERFAMILY SSF82549 9 279 5.23E-66 T 14-10-2018 Theos_0957 1ba1d246af66d3697c4ded05463f48a4 283 Gene3D G3DSA:3.30.1180.10 159 280 1.2E-25 T 14-10-2018 Theos_0957 1ba1d246af66d3697c4ded05463f48a4 283 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 11 278 1.1E-67 T 14-10-2018 IPR003797 DegV Theos_2034 8c9cc4799e1d8e04b8245681ed4e4487 267 PIRSF PIRSF035875 3 266 6.6E-36 T 14-10-2018 IPR017039 Virulence factor BrkB Theos_2034 8c9cc4799e1d8e04b8245681ed4e4487 267 Pfam PF03631 Virulence factor BrkB 18 265 1.5E-31 T 14-10-2018 IPR017039 Virulence factor BrkB Theos_0425 8ef6ed763dc2ced05e4ef4807875f4bc 595 SUPERFAMILY SSF143968 478 595 3.4E-17 T 14-10-2018 Theos_0425 8ef6ed763dc2ced05e4ef4807875f4bc 595 Gene3D G3DSA:3.40.1670.10 335 450 1.1E-23 T 14-10-2018 Theos_0425 8ef6ed763dc2ced05e4ef4807875f4bc 595 SUPERFAMILY SSF50475 2 320 2.16E-106 T 14-10-2018 Theos_0425 8ef6ed763dc2ced05e4ef4807875f4bc 595 SUPERFAMILY SSF143968 321 461 9.55E-37 T 14-10-2018 Theos_0425 8ef6ed763dc2ced05e4ef4807875f4bc 595 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 9 426 1.7E-149 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Theos_0425 8ef6ed763dc2ced05e4ef4807875f4bc 595 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 8 451 6.9E-114 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Theos_0425 8ef6ed763dc2ced05e4ef4807875f4bc 595 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 8 443 7.5E-186 T 14-10-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 Theos_2294 7671881b2b015b69e51bb84192e053da 308 Gene3D G3DSA:3.50.50.60 4 85 1.3E-18 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2294 7671881b2b015b69e51bb84192e053da 308 Pfam PF01266 FAD dependent oxidoreductase 4 300 1.7E-36 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Theos_2294 7671881b2b015b69e51bb84192e053da 308 Gene3D G3DSA:3.50.50.60 124 301 2.2E-25 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2294 7671881b2b015b69e51bb84192e053da 308 Gene3D G3DSA:3.30.9.10 86 104 1.3E-18 T 14-10-2018 Theos_2294 7671881b2b015b69e51bb84192e053da 308 SUPERFAMILY SSF51905 3 231 1.42E-24 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2294 7671881b2b015b69e51bb84192e053da 308 Gene3D G3DSA:3.30.9.10 112 267 2.2E-25 T 14-10-2018 Theos_2067 c95ab4c4474f60d69b16ee7cc8129c64 164 Pfam PF02559 CarD-like/TRCF domain 4 108 8.4E-14 T 14-10-2018 IPR003711 CarD-like/TRCF domain Theos_2067 c95ab4c4474f60d69b16ee7cc8129c64 164 SMART SM01058 3 113 4.6E-21 T 14-10-2018 IPR003711 CarD-like/TRCF domain Theos_2067 c95ab4c4474f60d69b16ee7cc8129c64 164 Gene3D G3DSA:1.20.58.1290 62 160 2.9E-38 T 14-10-2018 Theos_2067 c95ab4c4474f60d69b16ee7cc8129c64 164 SUPERFAMILY SSF141259 2 69 2.88E-12 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily Theos_2067 c95ab4c4474f60d69b16ee7cc8129c64 164 Gene3D G3DSA:2.30.30.840 1 61 8.4E-19 T 14-10-2018 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 Pfam PF09339 IclR helix-turn-helix domain 5 48 7.9E-8 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 SUPERFAMILY SSF50249 186 592 3.31E-134 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 SMART SM00316 596 675 2.6E-6 T 14-10-2018 IPR022967 RNA-binding domain, S1 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 Pfam PF00575 S1 RNA binding domain 596 630 1.1E-5 T 14-10-2018 IPR003029 S1 domain GO:0003676 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 SUPERFAMILY SSF50249 598 672 8.58E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 SMART SM00955 226 549 9.5E-159 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 51 672 7.1E-147 T 14-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 Gene3D G3DSA:2.40.50.140 44 119 3.1E-10 T 14-10-2018 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 SUPERFAMILY SSF46785 1 54 1.18E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 Gene3D G3DSA:2.40.50.140 593 677 1.9E-11 T 14-10-2018 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 Hamap MF_01895 Ribonuclease R [rnr]. 19 675 51.917 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 SUPERFAMILY SSF50249 109 203 3.22E-13 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 SUPERFAMILY SSF50249 54 118 9.7E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 672 1.3E-192 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 SMART SM00357 59 116 0.0018 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 ProSitePatterns PS01175 Ribonuclease II family signature. 516 540 - T 14-10-2018 IPR022966 Ribonuclease II/R, conserved site Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 Pfam PF08206 Ribonuclease B OB domain 60 114 5.0E-11 T 14-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain Theos_0924 05aef8e7dceeaf3528bd61a689bf9136 702 Pfam PF00773 RNB domain 226 548 1.1E-112 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Theos_1741 cf7cb2cc0f1062faa66498291bd28652 101 SUPERFAMILY SSF54909 1 94 8.05E-15 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Theos_1741 cf7cb2cc0f1062faa66498291bd28652 101 Pfam PF07876 Stress responsive A/B Barrel Domain 5 92 4.7E-12 T 14-10-2018 IPR013097 Stress responsive alpha-beta barrel Theos_1741 cf7cb2cc0f1062faa66498291bd28652 101 SMART SM00886 2 94 1.0E-13 T 14-10-2018 IPR013097 Stress responsive alpha-beta barrel Theos_1741 cf7cb2cc0f1062faa66498291bd28652 101 Gene3D G3DSA:3.30.70.100 1 98 1.8E-14 T 14-10-2018 Theos_0510 b2461a4167853e39cf98cf7a11930ac6 237 SUPERFAMILY SSF52540 3 235 2.22E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0510 b2461a4167853e39cf98cf7a11930ac6 237 PIRSF PIRSF039137 1 237 3.5E-112 T 14-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 Theos_0510 b2461a4167853e39cf98cf7a11930ac6 237 Pfam PF00005 ABC transporter 19 164 1.2E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0510 b2461a4167853e39cf98cf7a11930ac6 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0510 b2461a4167853e39cf98cf7a11930ac6 237 SMART SM00382 28 228 6.4E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0510 b2461a4167853e39cf98cf7a11930ac6 237 Gene3D G3DSA:3.40.50.300 2 237 1.3E-67 T 14-10-2018 Theos_1525 3a81b11eb4d174ecc16978516f8d945c 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.0E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1525 3a81b11eb4d174ecc16978516f8d945c 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.0E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1525 3a81b11eb4d174ecc16978516f8d945c 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.0E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1525 3a81b11eb4d174ecc16978516f8d945c 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 1.0E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1525 3a81b11eb4d174ecc16978516f8d945c 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.0E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1525 3a81b11eb4d174ecc16978516f8d945c 277 Gene3D G3DSA:3.40.50.720 3 257 2.3E-64 T 14-10-2018 Theos_1525 3a81b11eb4d174ecc16978516f8d945c 277 Pfam PF00106 short chain dehydrogenase 5 182 8.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1525 3a81b11eb4d174ecc16978516f8d945c 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_1525 3a81b11eb4d174ecc16978516f8d945c 277 SUPERFAMILY SSF51735 3 245 1.03E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1009 8ec046392ab5bcf71e515583fc0864fa 282 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 24 111 4.1E-26 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 Theos_1009 8ec046392ab5bcf71e515583fc0864fa 282 SUPERFAMILY SSF51690 113 277 7.46E-59 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 Theos_1009 8ec046392ab5bcf71e515583fc0864fa 282 Gene3D G3DSA:3.20.20.70 127 269 1.1E-108 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1009 8ec046392ab5bcf71e515583fc0864fa 282 SUPERFAMILY SSF54675 8 112 2.04E-30 T 14-10-2018 Theos_1009 8ec046392ab5bcf71e515583fc0864fa 282 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 113 277 3.7E-59 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 Theos_1009 8ec046392ab5bcf71e515583fc0864fa 282 Gene3D G3DSA:3.90.1170.20 18 277 1.1E-108 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 Theos_1009 8ec046392ab5bcf71e515583fc0864fa 282 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 15 277 3.8E-98 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 Theos_1009 8ec046392ab5bcf71e515583fc0864fa 282 PIRSF PIRSF006250 6 281 1.7E-92 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 Theos_2360 5d85091603023a610dc47a9a99ec00af 260 SMART SM00382 26 213 4.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2360 5d85091603023a610dc47a9a99ec00af 260 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2360 5d85091603023a610dc47a9a99ec00af 260 SUPERFAMILY SSF52540 2 225 2.55E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2360 5d85091603023a610dc47a9a99ec00af 260 Pfam PF00005 ABC transporter 17 165 1.5E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2360 5d85091603023a610dc47a9a99ec00af 260 Gene3D G3DSA:3.40.50.300 1 245 7.4E-62 T 14-10-2018 Theos_2064 da204f059e0102ea0f235fec70ca5c90 168 Pfam PF09988 Uncharacterized metal-binding protein (DUF2227) 2 160 3.4E-39 T 14-10-2018 IPR019250 Protein of unknown function DUF2227, metal-binding Theos_1188 ee84aa7c450ae661bf3d76348953f9c6 254 Gene3D G3DSA:3.40.190.10 29 247 8.4E-90 T 14-10-2018 Theos_1188 ee84aa7c450ae661bf3d76348953f9c6 254 SMART SM00062 31 250 2.7E-66 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Theos_1188 ee84aa7c450ae661bf3d76348953f9c6 254 Gene3D G3DSA:3.40.190.10 115 212 8.4E-90 T 14-10-2018 Theos_1188 ee84aa7c450ae661bf3d76348953f9c6 254 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 54 67 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site Theos_1188 ee84aa7c450ae661bf3d76348953f9c6 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 249 1.6E-66 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Theos_1188 ee84aa7c450ae661bf3d76348953f9c6 254 SUPERFAMILY SSF53850 2 250 1.43E-70 T 14-10-2018 Theos_1379 e329e5f1f2c1c34a9999e602e75f5f5d 188 Pfam PF00578 AhpC/TSA family 13 131 2.2E-15 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Theos_1379 e329e5f1f2c1c34a9999e602e75f5f5d 188 Gene3D G3DSA:3.40.30.10 2 188 1.3E-55 T 14-10-2018 Theos_1379 e329e5f1f2c1c34a9999e602e75f5f5d 188 SUPERFAMILY SSF52833 5 183 2.88E-50 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_2035 a4bbebedd6b36f7ff2ba4ad4ba3675e7 185 Pfam PF07721 Tetratricopeptide repeat 7 26 0.06 T 14-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 Theos_2035 a4bbebedd6b36f7ff2ba4ad4ba3675e7 185 Pfam PF07721 Tetratricopeptide repeat 30 53 0.0059 T 14-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 Theos_2035 a4bbebedd6b36f7ff2ba4ad4ba3675e7 185 Pfam PF07721 Tetratricopeptide repeat 65 86 0.19 T 14-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 Theos_2035 a4bbebedd6b36f7ff2ba4ad4ba3675e7 185 SUPERFAMILY SSF48452 6 169 1.9E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2035 a4bbebedd6b36f7ff2ba4ad4ba3675e7 185 Gene3D G3DSA:1.25.40.10 25 184 2.4E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0533 61a46be569a5ccb8573c91ff59263ec3 272 Gene3D G3DSA:3.90.1200.10 77 266 1.1E-10 T 14-10-2018 Theos_0533 61a46be569a5ccb8573c91ff59263ec3 272 SUPERFAMILY SSF56112 7 241 1.41E-22 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Theos_0533 61a46be569a5ccb8573c91ff59263ec3 272 Pfam PF01636 Phosphotransferase enzyme family 27 192 8.0E-12 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase Theos_0623 aff0528ecf3fb368c3d767a56bf7991b 126 Gene3D G3DSA:1.10.1510.10 1 67 3.8E-6 T 14-10-2018 Theos_0623 aff0528ecf3fb368c3d767a56bf7991b 126 SUPERFAMILY SSF89095 2 124 7.32E-15 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 Theos_0623 aff0528ecf3fb368c3d767a56bf7991b 126 Pfam PF09424 Yqey-like protein 62 116 3.7E-5 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 Theos_0623 aff0528ecf3fb368c3d767a56bf7991b 126 Pfam PF09424 Yqey-like protein 4 51 1.6E-5 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 Theos_0693 f631062b1d95d80aab8800be4fd040aa 148 Gene3D G3DSA:1.10.20.10 1 148 8.2E-60 T 14-10-2018 IPR009072 Histone-fold GO:0046982 Theos_0693 f631062b1d95d80aab8800be4fd040aa 148 Pfam PF09123 Domain of unknown function (DUF1931) 8 145 3.4E-54 T 14-10-2018 IPR015207 Protein of unknown function DUF1931 Theos_0693 f631062b1d95d80aab8800be4fd040aa 148 SUPERFAMILY SSF47113 1 148 2.79E-52 T 14-10-2018 IPR009072 Histone-fold GO:0046982 Theos_1848 3641711851aab0daed55ab270dd11fa6 210 SUPERFAMILY SSF161098 5 208 1.83E-24 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1848 3641711851aab0daed55ab270dd11fa6 210 Gene3D G3DSA:1.10.3720.10 1 210 5.4E-21 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0504 15f00d3429ac8b81eb8b3da08e1c1df6 600 Gene3D G3DSA:3.40.50.300 349 600 6.0E-84 T 14-10-2018 Theos_0504 15f00d3429ac8b81eb8b3da08e1c1df6 600 Pfam PF00664 ABC transporter transmembrane region 30 307 2.1E-59 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Theos_0504 15f00d3429ac8b81eb8b3da08e1c1df6 600 Pfam PF00005 ABC transporter 376 526 1.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0504 15f00d3429ac8b81eb8b3da08e1c1df6 600 SUPERFAMILY SSF52540 342 597 2.34E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0504 15f00d3429ac8b81eb8b3da08e1c1df6 600 SUPERFAMILY SSF90123 17 340 3.4E-85 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Theos_0504 15f00d3429ac8b81eb8b3da08e1c1df6 600 SMART SM00382 385 572 8.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0504 15f00d3429ac8b81eb8b3da08e1c1df6 600 Gene3D G3DSA:1.20.1560.10 2 340 1.5E-98 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Theos_0574 72e16160005647c044fcc84d815dbcbe 313 Pfam PF00990 Diguanylate cyclase, GGDEF domain 164 305 1.5E-40 T 14-10-2018 IPR000160 GGDEF domain Theos_0574 72e16160005647c044fcc84d815dbcbe 313 SUPERFAMILY SSF55073 165 308 3.45E-45 T 14-10-2018 IPR029787 Nucleotide cyclase Theos_0574 72e16160005647c044fcc84d815dbcbe 313 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 158 307 6.4E-42 T 14-10-2018 IPR000160 GGDEF domain Theos_0574 72e16160005647c044fcc84d815dbcbe 313 SMART SM00267 154 309 5.1E-51 T 14-10-2018 IPR000160 GGDEF domain Theos_0574 72e16160005647c044fcc84d815dbcbe 313 Gene3D G3DSA:3.30.70.270 156 311 1.1E-52 T 14-10-2018 Theos_1950 b64230c2887186287bf59b200de63694 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 7 54 2.8E-21 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1950 b64230c2887186287bf59b200de63694 54 SUPERFAMILY SSF57829 2 53 5.92E-20 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Theos_1950 b64230c2887186287bf59b200de63694 54 Pfam PF00471 Ribosomal protein L33 8 53 2.6E-22 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1950 b64230c2887186287bf59b200de63694 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 19.275 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1950 b64230c2887186287bf59b200de63694 54 Gene3D G3DSA:2.20.28.120 1 54 2.0E-26 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1950 b64230c2887186287bf59b200de63694 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1443 95b4259bb8c69b05e825d394e153db8e 275 ProSitePatterns PS01229 Hypothetical cof family signature 2. 225 247 - T 14-10-2018 Theos_1443 95b4259bb8c69b05e825d394e153db8e 275 SUPERFAMILY SSF56784 8 272 1.16E-35 T 14-10-2018 IPR036412 HAD-like superfamily Theos_1443 95b4259bb8c69b05e825d394e153db8e 275 Pfam PF08282 haloacid dehalogenase-like hydrolase 10 271 1.9E-22 T 14-10-2018 Theos_1443 95b4259bb8c69b05e825d394e153db8e 275 Gene3D G3DSA:3.30.1240.10 94 200 1.3E-35 T 14-10-2018 Theos_1443 95b4259bb8c69b05e825d394e153db8e 275 Gene3D G3DSA:3.40.50.1000 8 270 1.3E-35 T 14-10-2018 IPR023214 HAD superfamily Theos_2192 4c2e14fe9ed88e7b34e79622505d221b 351 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 347 45.649 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 Theos_2192 4c2e14fe9ed88e7b34e79622505d221b 351 Pfam PF01409 tRNA synthetases class II core domain (F) 86 347 3.5E-96 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 Theos_2192 4c2e14fe9ed88e7b34e79622505d221b 351 SUPERFAMILY SSF55681 86 347 4.15E-74 T 14-10-2018 Theos_2192 4c2e14fe9ed88e7b34e79622505d221b 351 SUPERFAMILY SSF46589 6 92 1.99E-20 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Theos_2192 4c2e14fe9ed88e7b34e79622505d221b 351 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 33 347 9.2E-92 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Theos_2192 4c2e14fe9ed88e7b34e79622505d221b 351 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 13 81 8.7E-20 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Theos_2192 4c2e14fe9ed88e7b34e79622505d221b 351 Gene3D G3DSA:3.30.930.10 1 351 1.2E-121 T 14-10-2018 Theos_2036 60ced768371f28fb6d6d1f68aa65d78c 409 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 315 336 - T 14-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Theos_2036 60ced768371f28fb6d6d1f68aa65d78c 409 PIRSF PIRSF000151 1 409 3.0E-158 T 14-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 Theos_2036 60ced768371f28fb6d6d1f68aa65d78c 409 Pfam PF00171 Aldehyde dehydrogenase family 35 275 4.0E-17 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Theos_2036 60ced768371f28fb6d6d1f68aa65d78c 409 Gene3D G3DSA:3.40.309.10 218 366 2.2E-154 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Theos_2036 60ced768371f28fb6d6d1f68aa65d78c 409 SUPERFAMILY SSF53720 4 407 5.76E-110 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_2036 60ced768371f28fb6d6d1f68aa65d78c 409 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 1 408 38.975 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Theos_2036 60ced768371f28fb6d6d1f68aa65d78c 409 Gene3D G3DSA:3.40.605.10 11 403 2.2E-154 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_2036 60ced768371f28fb6d6d1f68aa65d78c 409 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 6 398 7.4E-131 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 Gene3D G3DSA:3.40.50.11540 165 331 2.6E-62 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 Pfam PF10531 SLBB domain 338 379 3.7E-8 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 SUPERFAMILY SSF142984 336 392 1.83E-10 T 14-10-2018 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 Gene3D G3DSA:1.20.1440.230 413 485 8.5E-13 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 419 484 7.5E-13 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 Gene3D G3DSA:3.10.20.600 332 411 1.4E-11 T 14-10-2018 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 SMART SM00928 415 460 2.9E-6 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 160 322 5.8E-46 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 SUPERFAMILY SSF140490 412 484 1.44E-14 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1375 ce51c9a953fcfb92fb44c5da1bc7b642 489 SUPERFAMILY SSF142019 128 327 2.35E-65 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1524 c304153052ce688c1380ed8d8ad3effa 415 Pfam PF01070 FMN-dependent dehydrogenase 33 412 2.8E-116 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 Theos_1524 c304153052ce688c1380ed8d8ad3effa 415 SUPERFAMILY SSF51395 27 411 2.2E-85 T 14-10-2018 Theos_1524 c304153052ce688c1380ed8d8ad3effa 415 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 311 317 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 Theos_1524 c304153052ce688c1380ed8d8ad3effa 415 PIRSF PIRSF000138 9 413 3.4E-111 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 Theos_2314 450675cd0a31be861c9aea0e714b43e1 174 SUPERFAMILY SSF53254 1 146 1.07E-47 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_2314 450675cd0a31be861c9aea0e714b43e1 174 SMART SM00855 2 140 3.7E-27 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Theos_2314 450675cd0a31be861c9aea0e714b43e1 174 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 144 5.7E-38 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Theos_2314 450675cd0a31be861c9aea0e714b43e1 174 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 Theos_2314 450675cd0a31be861c9aea0e714b43e1 174 Gene3D G3DSA:3.40.50.1240 1 169 2.5E-53 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_2314 450675cd0a31be861c9aea0e714b43e1 174 PIRSF PIRSF000709 1 144 1.9E-6 T 14-10-2018 Theos_0211 75255f25b87309cf10953b6b5e8211ad 380 Pfam PF01676 Metalloenzyme superfamily 2 370 2.0E-23 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 Theos_0211 75255f25b87309cf10953b6b5e8211ad 380 Gene3D G3DSA:3.40.720.10 2 379 2.6E-138 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Theos_0211 75255f25b87309cf10953b6b5e8211ad 380 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 377 3.0E-119 T 14-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 Theos_0211 75255f25b87309cf10953b6b5e8211ad 380 Hamap MF_00740 Phosphopentomutase [deoB]. 1 380 43.794 T 14-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 Theos_0211 75255f25b87309cf10953b6b5e8211ad 380 PIRSF PIRSF001491 1 380 9.3E-135 T 14-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 Theos_0211 75255f25b87309cf10953b6b5e8211ad 380 Gene3D G3DSA:3.30.70.1250 93 212 2.6E-138 T 14-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 Theos_0211 75255f25b87309cf10953b6b5e8211ad 380 SUPERFAMILY SSF53649 1 380 7.59E-64 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Theos_0211 75255f25b87309cf10953b6b5e8211ad 380 SUPERFAMILY SSF143856 95 212 9.15E-41 T 14-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 Theos_0622 9000120b5fb06283262b1b7b151a0d1e 182 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Theos_0622 9000120b5fb06283262b1b7b151a0d1e 182 SUPERFAMILY SSF55811 4 177 1.04E-38 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Theos_0622 9000120b5fb06283262b1b7b151a0d1e 182 PRINTS PR00502 NUDIX hydrolase family signature 84 99 1.5E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_0622 9000120b5fb06283262b1b7b151a0d1e 182 PRINTS PR00502 NUDIX hydrolase family signature 70 84 1.5E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_0622 9000120b5fb06283262b1b7b151a0d1e 182 Pfam PF00293 NUDIX domain 45 154 2.8E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Theos_0622 9000120b5fb06283262b1b7b151a0d1e 182 Gene3D G3DSA:3.90.79.10 1 182 3.3E-54 T 14-10-2018 Theos_2023 2e226923a0f6f92b716c105911c0518d 80 SUPERFAMILY SSF55248 2 78 4.32E-28 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Theos_2023 2e226923a0f6f92b716c105911c0518d 80 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 2 75 1.6E-25 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Theos_2023 2e226923a0f6f92b716c105911c0518d 80 Gene3D G3DSA:3.30.1360.20 1 79 4.2E-30 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Theos_0205 fac72cc7af85ec6c33769285c30cc83c 403 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2 392 6.1E-119 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Theos_0205 fac72cc7af85ec6c33769285c30cc83c 403 PIRSF PIRSF004640 1 401 2.5E-132 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Theos_0205 fac72cc7af85ec6c33769285c30cc83c 403 SUPERFAMILY SSF56014 290 396 6.28E-7 T 14-10-2018 Theos_0205 fac72cc7af85ec6c33769285c30cc83c 403 SUPERFAMILY SSF51717 9 234 3.14E-5 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_0205 fac72cc7af85ec6c33769285c30cc83c 403 Gene3D G3DSA:3.20.20.20 1 285 2.2E-106 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_0205 fac72cc7af85ec6c33769285c30cc83c 403 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 1 394 30.604 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Theos_0205 fac72cc7af85ec6c33769285c30cc83c 403 Gene3D G3DSA:3.30.413.10 286 402 1.7E-39 T 14-10-2018 Theos_0205 fac72cc7af85ec6c33769285c30cc83c 403 Pfam PF04551 GcpE protein 6 392 1.5E-113 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Theos_1868 b9599216937ae39644de1fbb2879b939 393 Pfam PF03600 Citrate transporter 26 327 5.5E-27 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 Theos_1868 b9599216937ae39644de1fbb2879b939 393 PRINTS PR00758 Arsenical pump membrane protein signature 266 290 2.1E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Theos_1868 b9599216937ae39644de1fbb2879b939 393 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 2.1E-7 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Theos_2435 4b69543ca03de479dc8c9728b09658aa 422 SUPERFAMILY SSF56327 160 421 4.4E-33 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Theos_2435 4b69543ca03de479dc8c9728b09658aa 422 Gene3D G3DSA:3.90.1820.20 1 415 2.0E-79 T 14-10-2018 Theos_2435 4b69543ca03de479dc8c9728b09658aa 422 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 188 393 1.5E-26 T 14-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 Theos_2435 4b69543ca03de479dc8c9728b09658aa 422 PRINTS PR00732 Glycosyl hydrolase family 4 signature 182 194 9.5E-10 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Theos_2435 4b69543ca03de479dc8c9728b09658aa 422 PRINTS PR00732 Glycosyl hydrolase family 4 signature 3 18 9.5E-10 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Theos_2435 4b69543ca03de479dc8c9728b09658aa 422 PRINTS PR00732 Glycosyl hydrolase family 4 signature 107 127 9.5E-10 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Theos_2435 4b69543ca03de479dc8c9728b09658aa 422 Pfam PF02056 Family 4 glycosyl hydrolase 3 174 2.7E-22 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Theos_2435 4b69543ca03de479dc8c9728b09658aa 422 SUPERFAMILY SSF51735 3 161 2.69E-20 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2072 2c4d2b955849e6b3e5e4a2c7affff9c6 353 Pfam PF00266 Aminotransferase class-V 3 316 1.6E-28 T 14-10-2018 IPR000192 Aminotransferase class V domain Theos_2072 2c4d2b955849e6b3e5e4a2c7affff9c6 353 Gene3D G3DSA:3.90.1150.10 3 334 1.3E-126 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_2072 2c4d2b955849e6b3e5e4a2c7affff9c6 353 PIRSF PIRSF000524 1 353 5.8E-97 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 Theos_2072 2c4d2b955849e6b3e5e4a2c7affff9c6 353 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 177 197 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Theos_2072 2c4d2b955849e6b3e5e4a2c7affff9c6 353 SUPERFAMILY SSF53383 2 350 2.79E-90 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_2072 2c4d2b955849e6b3e5e4a2c7affff9c6 353 Gene3D G3DSA:3.40.640.10 12 252 1.3E-126 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0111 c504000de6edfbe99189418d98972851 430 SUPERFAMILY SSF101960 10 428 6.67E-114 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Theos_0111 c504000de6edfbe99189418d98972851 430 Pfam PF01458 Uncharacterized protein family (UPF0051) 181 402 1.2E-68 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Theos_0111 c504000de6edfbe99189418d98972851 430 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 147 419 5.0E-73 T 14-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 Theos_2148 7345f476a23abf1fa90955d096ca208c 542 Pfam PF14104 Domain of unknown function (DUF4277) 8 114 1.4E-35 T 14-10-2018 IPR025457 Domain of unknown function DUF4277 Theos_2148 7345f476a23abf1fa90955d096ca208c 542 Pfam PF01609 Transposase DDE domain 129 465 1.7E-11 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 Gene3D G3DSA:2.160.10.10 249 436 1.6E-54 T 14-10-2018 Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 391 424 2.6E-8 T 14-10-2018 IPR001451 Hexapeptide repeat Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 265 294 1.1E-4 T 14-10-2018 IPR001451 Hexapeptide repeat Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 450 1.9E-168 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 SUPERFAMILY SSF53448 5 248 2.09E-61 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 448 39.918 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 Gene3D G3DSA:3.90.550.10 3 247 2.4E-71 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 SUPERFAMILY SSF51161 251 434 4.53E-48 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 399 427 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 Theos_1589 8bddbaa37dc2c7c110ee9431a5b43b1b 453 Pfam PF12804 MobA-like NTP transferase domain 5 128 1.3E-21 T 14-10-2018 IPR025877 MobA-like NTP transferase Theos_2190 92d033a6eb2c26fb53125db3948712dd 148 Pfam PF01850 PIN domain 4 128 3.1E-7 T 14-10-2018 IPR002716 PIN domain Theos_2190 92d033a6eb2c26fb53125db3948712dd 148 SUPERFAMILY SSF88723 4 130 8.18E-14 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_2190 92d033a6eb2c26fb53125db3948712dd 148 Gene3D G3DSA:3.40.50.1010 3 132 2.2E-22 T 14-10-2018 Theos_1058 13bd69c4dab07671b34d904dbdb5a552 139 Pfam PF02082 Transcriptional regulator 8 84 1.5E-21 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Theos_1058 13bd69c4dab07671b34d904dbdb5a552 139 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 50 68 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site Theos_1058 13bd69c4dab07671b34d904dbdb5a552 139 SUPERFAMILY SSF46785 12 134 1.58E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1058 13bd69c4dab07671b34d904dbdb5a552 139 Gene3D G3DSA:1.10.10.10 5 138 2.4E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1058 13bd69c4dab07671b34d904dbdb5a552 139 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 7 134 7.4E-27 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Theos_1941 7673558f5df832f82a8fb5d3874de405 263 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 262 3.5E-75 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Theos_1941 7673558f5df832f82a8fb5d3874de405 263 Pfam PF01255 Putative undecaprenyl diphosphate synthase 36 262 2.0E-78 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Theos_1941 7673558f5df832f82a8fb5d3874de405 263 Gene3D G3DSA:3.40.1180.10 15 263 2.5E-95 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Theos_1941 7673558f5df832f82a8fb5d3874de405 263 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 263 39.589 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Theos_1941 7673558f5df832f82a8fb5d3874de405 263 SUPERFAMILY SSF64005 27 258 9.29E-80 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Theos_1941 7673558f5df832f82a8fb5d3874de405 263 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 208 225 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 Gene3D G3DSA:3.40.50.300 12 181 3.4E-53 T 14-10-2018 Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 Pfam PF01202 Shikimate kinase 19 175 1.3E-44 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 SUPERFAMILY SSF52540 12 175 1.94E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 ProSitePatterns PS01128 Shikimate kinase signature. 66 91 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 Hamap MF_00109 Shikimate kinase [aroK]. 10 176 27.849 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 PRINTS PR01100 Shikimate kinase family signature 65 73 5.5E-16 T 14-10-2018 Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 PRINTS PR01100 Shikimate kinase family signature 37 50 5.5E-16 T 14-10-2018 Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 PRINTS PR01100 Shikimate kinase family signature 83 92 5.5E-16 T 14-10-2018 Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 PRINTS PR01100 Shikimate kinase family signature 104 121 5.5E-16 T 14-10-2018 Theos_0433 22a51ee4dcbbee93d4aaa5ae7839483a 184 PRINTS PR01100 Shikimate kinase family signature 13 28 5.5E-16 T 14-10-2018 Theos_1881 d51207bd26403a6b900492aca93311d5 206 SUPERFAMILY SSF48452 62 167 9.49E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1881 d51207bd26403a6b900492aca93311d5 206 Pfam PF13181 Tetratricopeptide repeat 143 167 0.056 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1881 d51207bd26403a6b900492aca93311d5 206 SMART SM00028 70 103 1.8 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1881 d51207bd26403a6b900492aca93311d5 206 SMART SM00028 104 137 2.7E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1881 d51207bd26403a6b900492aca93311d5 206 SMART SM00028 138 171 22.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1881 d51207bd26403a6b900492aca93311d5 206 Pfam PF13432 Tetratricopeptide repeat 83 138 4.9E-10 T 14-10-2018 Theos_1881 d51207bd26403a6b900492aca93311d5 206 Gene3D G3DSA:1.25.40.10 13 179 7.3E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1401 0a41901aa18d2098c75e7eacbd041988 302 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 4 297 28.342 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Theos_1401 0a41901aa18d2098c75e7eacbd041988 302 Gene3D G3DSA:1.10.20.140 111 179 3.1E-83 T 14-10-2018 Theos_1401 0a41901aa18d2098c75e7eacbd041988 302 Pfam PF01715 IPP transferase 38 275 3.0E-68 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Theos_1401 0a41901aa18d2098c75e7eacbd041988 302 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 7 280 5.6E-69 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Theos_1401 0a41901aa18d2098c75e7eacbd041988 302 Gene3D G3DSA:3.40.50.300 8 275 3.1E-83 T 14-10-2018 Theos_1401 0a41901aa18d2098c75e7eacbd041988 302 SUPERFAMILY SSF52540 6 143 4.94E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1245 af76ecffe50411a9ead4f06ed71db289 100 Pfam PF01909 Nucleotidyltransferase domain 11 95 1.1E-13 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Theos_1245 af76ecffe50411a9ead4f06ed71db289 100 SUPERFAMILY SSF81301 10 98 1.75E-23 T 14-10-2018 Theos_1245 af76ecffe50411a9ead4f06ed71db289 100 Gene3D G3DSA:3.30.460.10 5 96 5.3E-25 T 14-10-2018 Theos_1494 87100165e8e5ea932e6061a2195e491b 441 Pfam PF07687 Peptidase dimerisation domain 180 338 1.5E-19 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain Theos_1494 87100165e8e5ea932e6061a2195e491b 441 Pfam PF01546 Peptidase family M20/M25/M40 69 435 1.4E-34 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 Theos_1494 87100165e8e5ea932e6061a2195e491b 441 SUPERFAMILY SSF55031 189 336 8.67E-5 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Theos_1494 87100165e8e5ea932e6061a2195e491b 441 Gene3D G3DSA:3.30.70.360 182 351 1.1E-147 T 14-10-2018 Theos_1494 87100165e8e5ea932e6061a2195e491b 441 Gene3D G3DSA:3.40.630.10 15 423 1.1E-147 T 14-10-2018 Theos_1494 87100165e8e5ea932e6061a2195e491b 441 SUPERFAMILY SSF53187 2 435 2.66E-55 T 14-10-2018 Theos_2459 2b78f01018817f49d86d226f03962ef6 396 SUPERFAMILY SSF53822 22 386 6.12E-94 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_2459 2b78f01018817f49d86d226f03962ef6 396 Pfam PF13458 Periplasmic binding protein 22 358 7.3E-80 T 14-10-2018 IPR028081 Leucine-binding protein domain Theos_2459 2b78f01018817f49d86d226f03962ef6 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 256 274 1.1E-10 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_2459 2b78f01018817f49d86d226f03962ef6 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 45 61 1.1E-10 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_2459 2b78f01018817f49d86d226f03962ef6 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 64 82 1.1E-10 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_2459 2b78f01018817f49d86d226f03962ef6 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 23 39 1.1E-10 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Theos_2459 2b78f01018817f49d86d226f03962ef6 396 Gene3D G3DSA:3.40.50.2300 44 359 5.0E-120 T 14-10-2018 Theos_2459 2b78f01018817f49d86d226f03962ef6 396 Gene3D G3DSA:3.40.50.2300 141 368 5.0E-120 T 14-10-2018 Theos_1989 b2ad8802f6108b3704fb271166c4e2e8 560 Pfam PF01432 Peptidase family M3 179 547 9.8E-25 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 Theos_1989 b2ad8802f6108b3704fb271166c4e2e8 560 SUPERFAMILY SSF55486 43 558 1.04E-76 T 14-10-2018 Theos_1989 b2ad8802f6108b3704fb271166c4e2e8 560 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 4 559 2.8E-176 T 14-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 Theos_1989 b2ad8802f6108b3704fb271166c4e2e8 560 Gene3D G3DSA:1.10.1370.30 28 560 9.7E-103 T 14-10-2018 Theos_1989 b2ad8802f6108b3704fb271166c4e2e8 560 Pfam PF08439 Oligopeptidase F 104 158 1.9E-4 T 14-10-2018 IPR013647 Oligopeptidase F, N-terminal domain Theos_1418 2c6885415db5d088592561870b7b48fe 422 SUPERFAMILY SSF56954 6 418 7.85E-32 T 14-10-2018 Theos_1418 2c6885415db5d088592561870b7b48fe 422 Pfam PF02321 Outer membrane efflux protein 26 192 2.3E-6 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Theos_1418 2c6885415db5d088592561870b7b48fe 422 Pfam PF02321 Outer membrane efflux protein 216 413 2.9E-14 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Theos_0689 e08167e2373077945ff3341da80b4ad2 137 Gene3D G3DSA:2.60.40.790 1 136 8.9E-29 T 14-10-2018 IPR008978 HSP20-like chaperone Theos_0689 e08167e2373077945ff3341da80b4ad2 137 SUPERFAMILY SSF49764 23 136 2.12E-30 T 14-10-2018 IPR008978 HSP20-like chaperone Theos_0689 e08167e2373077945ff3341da80b4ad2 137 Pfam PF00011 Hsp20/alpha crystallin family 36 135 2.6E-17 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Theos_2434 8f73f5deb5bb370a2a4ed7a9c40157d9 418 SUPERFAMILY SSF55347 136 346 8.5E-21 T 14-10-2018 Theos_2434 8f73f5deb5bb370a2a4ed7a9c40157d9 418 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 142 213 4.4E-5 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 Theos_2434 8f73f5deb5bb370a2a4ed7a9c40157d9 418 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 130 4.0E-20 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Theos_2434 8f73f5deb5bb370a2a4ed7a9c40157d9 418 Gene3D G3DSA:3.40.50.720 2 131 4.9E-28 T 14-10-2018 Theos_2434 8f73f5deb5bb370a2a4ed7a9c40157d9 418 SUPERFAMILY SSF51735 4 157 9.14E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0424 1340fa70b0da0adbe4a7e638c4c9487f 112 Hamap MF_00048 UPF0102 protein YraN [yraN]. 2 109 19.363 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 Theos_0424 1340fa70b0da0adbe4a7e638c4c9487f 112 SUPERFAMILY SSF52980 5 105 6.87E-18 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_0424 1340fa70b0da0adbe4a7e638c4c9487f 112 Pfam PF02021 Uncharacterised protein family UPF0102 9 95 6.7E-21 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 Theos_0424 1340fa70b0da0adbe4a7e638c4c9487f 112 Gene3D G3DSA:3.40.1350.10 8 109 7.7E-22 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 Theos_1448 f7ff17679457e45382114dbef5d2464b 177 Gene3D G3DSA:2.30.110.10 2 157 1.2E-28 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Theos_1448 f7ff17679457e45382114dbef5d2464b 177 SMART SM00903 6 152 6.8E-4 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Theos_1448 f7ff17679457e45382114dbef5d2464b 177 Pfam PF01613 Flavin reductase like domain 18 153 1.3E-11 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Theos_1448 f7ff17679457e45382114dbef5d2464b 177 SUPERFAMILY SSF50475 3 159 3.11E-26 T 14-10-2018 Theos_0389 6dd3a5091479283492ed8cc41dff601e 213 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 39 210 9.6E-45 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG Theos_0389 6dd3a5091479283492ed8cc41dff601e 213 Pfam PF03641 Possible lysine decarboxylase 81 209 2.0E-32 T 14-10-2018 IPR031100 LOG family Theos_0389 6dd3a5091479283492ed8cc41dff601e 213 Gene3D G3DSA:3.40.50.450 15 212 4.0E-72 T 14-10-2018 Theos_0389 6dd3a5091479283492ed8cc41dff601e 213 SUPERFAMILY SSF102405 7 211 8.85E-66 T 14-10-2018 Theos_1003 dc6a4096d1071ea1be4059b1678d7365 437 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 425 4.1E-97 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Theos_1003 dc6a4096d1071ea1be4059b1678d7365 437 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 431 5.2E-102 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Theos_1003 dc6a4096d1071ea1be4059b1678d7365 437 PIRSF PIRSF006066 5 437 1.6E-85 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Theos_0505 33231ef3748105f42a680ffa034995c6 387 Gene3D G3DSA:3.40.1190.10 1 265 2.0E-67 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_0505 33231ef3748105f42a680ffa034995c6 387 SUPERFAMILY SSF53244 265 379 3.3E-17 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_0505 33231ef3748105f42a680ffa034995c6 387 Pfam PF08245 Mur ligase middle domain 45 179 2.2E-7 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Theos_0505 33231ef3748105f42a680ffa034995c6 387 SUPERFAMILY SSF53623 1 263 1.83E-66 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_0505 33231ef3748105f42a680ffa034995c6 387 Gene3D G3DSA:3.90.190.20 266 383 9.1E-16 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_0505 33231ef3748105f42a680ffa034995c6 387 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 378 4.5E-79 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 Gene3D G3DSA:1.10.150.380 296 400 3.3E-24 T 14-10-2018 Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 SMART SM00845 326 473 2.7E-48 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 Pfam PF02637 GatB domain 337 473 2.0E-37 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 SUPERFAMILY SSF55931 10 295 6.08E-109 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 8 474 36.443 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 Gene3D G3DSA:1.10.10.410 413 475 1.1E-15 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 9 473 1.6E-150 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 SUPERFAMILY SSF89095 296 399 9.55E-20 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 Pfam PF02934 GatB/GatE catalytic domain 11 286 1.2E-107 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 Theos_1972 b39fbba12e895e561f68a7014f80c78a 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 144 158 - T 14-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 Theos_2204 695774a23ab5eb539fb61778fced0138 249 SUPERFAMILY SSF52540 7 246 5.93E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2204 695774a23ab5eb539fb61778fced0138 249 PRINTS PR00091 Nitrogenase component II signature 35 50 7.2E-5 T 14-10-2018 Theos_2204 695774a23ab5eb539fb61778fced0138 249 PRINTS PR00091 Nitrogenase component II signature 13 26 7.2E-5 T 14-10-2018 Theos_2204 695774a23ab5eb539fb61778fced0138 249 Gene3D G3DSA:3.40.50.300 3 249 5.0E-88 T 14-10-2018 Theos_2204 695774a23ab5eb539fb61778fced0138 249 Pfam PF13614 AAA domain 7 170 9.5E-45 T 14-10-2018 IPR025669 AAA domain Theos_2204 695774a23ab5eb539fb61778fced0138 249 PIRSF PIRSF009320 6 249 8.0E-29 T 14-10-2018 Theos_0452 73abba535168d13592dd9f8401e2af68 266 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 19 243 3.5E-31 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Theos_0452 73abba535168d13592dd9f8401e2af68 266 SUPERFAMILY SSF51306 28 244 1.12E-43 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Theos_0452 73abba535168d13592dd9f8401e2af68 266 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 100 112 4.7E-12 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Theos_0452 73abba535168d13592dd9f8401e2af68 266 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 202 221 4.7E-12 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Theos_0452 73abba535168d13592dd9f8401e2af68 266 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 4.7E-12 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Theos_0452 73abba535168d13592dd9f8401e2af68 266 Pfam PF00717 Peptidase S24-like 36 114 2.2E-7 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Theos_0452 73abba535168d13592dd9f8401e2af68 266 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 Theos_0452 73abba535168d13592dd9f8401e2af68 266 Gene3D G3DSA:2.10.109.10 29 242 1.3E-24 T 14-10-2018 Theos_0452 73abba535168d13592dd9f8401e2af68 266 ProSitePatterns PS00760 Signal peptidases I lysine active site. 102 114 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 Theos_0452 73abba535168d13592dd9f8401e2af68 266 Gene3D G3DSA:2.170.230.10 111 201 1.3E-24 T 14-10-2018 Theos_1930 4bffb629178c16c07f20ee0db2de4d84 516 SUPERFAMILY SSF88713 2 413 3.5E-121 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Theos_1930 4bffb629178c16c07f20ee0db2de4d84 516 Pfam PF03065 Glycosyl hydrolase family 57 5 363 1.1E-40 T 14-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 Theos_1930 4bffb629178c16c07f20ee0db2de4d84 516 SUPERFAMILY SSF88688 413 515 1.96E-31 T 14-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily Theos_1930 4bffb629178c16c07f20ee0db2de4d84 516 Gene3D G3DSA:3.20.110.10 1 413 3.5E-165 T 14-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily Theos_1930 4bffb629178c16c07f20ee0db2de4d84 516 Pfam PF09210 Domain of unknown function (DUF1957) 431 515 1.4E-21 T 14-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 Theos_1930 4bffb629178c16c07f20ee0db2de4d84 516 Gene3D G3DSA:1.20.1430.10 414 516 4.3E-34 T 14-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 Theos_0301 29501221bb7de6b5b747c2a285b2dbc5 37 SUPERFAMILY SSF57840 1 37 2.49E-18 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0301 29501221bb7de6b5b747c2a285b2dbc5 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.3E-24 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0301 29501221bb7de6b5b747c2a285b2dbc5 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0301 29501221bb7de6b5b747c2a285b2dbc5 37 Pfam PF00444 Ribosomal protein L36 1 37 7.0E-23 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0301 29501221bb7de6b5b747c2a285b2dbc5 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 8.0E-9 T 14-10-2018 Theos_0301 29501221bb7de6b5b747c2a285b2dbc5 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 19.15 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1056 1c13b89a211c1267e3c9f35ac5dc8fd2 476 Gene3D G3DSA:1.20.210.10 1 471 2.7E-121 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1056 1c13b89a211c1267e3c9f35ac5dc8fd2 476 SUPERFAMILY SSF81442 12 460 2.35E-71 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1056 1c13b89a211c1267e3c9f35ac5dc8fd2 476 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 203 259 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1056 1c13b89a211c1267e3c9f35ac5dc8fd2 476 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 16 445 6.6E-74 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1759 8b998b7026c4a274dc56979642783a12 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1759 8b998b7026c4a274dc56979642783a12 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1759 8b998b7026c4a274dc56979642783a12 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1759 8b998b7026c4a274dc56979642783a12 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1759 8b998b7026c4a274dc56979642783a12 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1759 8b998b7026c4a274dc56979642783a12 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1759 8b998b7026c4a274dc56979642783a12 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1759 8b998b7026c4a274dc56979642783a12 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1759 8b998b7026c4a274dc56979642783a12 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1759 8b998b7026c4a274dc56979642783a12 234 Gene3D G3DSA:3.40.50.720 1 233 5.8E-66 T 14-10-2018 Theos_1759 8b998b7026c4a274dc56979642783a12 234 SUPERFAMILY SSF51735 2 234 5.32E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1759 8b998b7026c4a274dc56979642783a12 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 233 3.4E-45 T 14-10-2018 Theos_0866 6a79c30c2b2343c4b7bcee50b03611a7 219 SUPERFAMILY SSF52821 118 219 1.57E-35 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0866 6a79c30c2b2343c4b7bcee50b03611a7 219 Gene3D G3DSA:3.40.250.10 123 219 5.3E-32 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0866 6a79c30c2b2343c4b7bcee50b03611a7 219 Gene3D G3DSA:3.40.250.10 11 113 1.1E-29 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0866 6a79c30c2b2343c4b7bcee50b03611a7 219 SMART SM00450 8 103 4.3E-24 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0866 6a79c30c2b2343c4b7bcee50b03611a7 219 SMART SM00450 121 216 7.2E-27 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0866 6a79c30c2b2343c4b7bcee50b03611a7 219 ProSitePatterns PS00380 Rhodanese signature 1. 144 155 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 Theos_0866 6a79c30c2b2343c4b7bcee50b03611a7 219 Pfam PF00581 Rhodanese-like domain 123 212 4.2E-18 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0866 6a79c30c2b2343c4b7bcee50b03611a7 219 Pfam PF00581 Rhodanese-like domain 10 99 2.1E-16 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0866 6a79c30c2b2343c4b7bcee50b03611a7 219 SUPERFAMILY SSF52821 4 106 3.14E-35 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_2045 89421dcccbb633ae0a57077e67a7b217 286 SMART SM00244 58 219 1.3E-10 T 14-10-2018 IPR001107 Band 7 domain Theos_2045 89421dcccbb633ae0a57077e67a7b217 286 Pfam PF01145 SPFH domain / Band 7 family 62 229 1.2E-26 T 14-10-2018 IPR001107 Band 7 domain Theos_2045 89421dcccbb633ae0a57077e67a7b217 286 Gene3D G3DSA:3.30.479.30 89 221 2.9E-10 T 14-10-2018 Theos_2045 89421dcccbb633ae0a57077e67a7b217 286 SUPERFAMILY SSF117892 96 222 5.62E-14 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily Theos_2029 a1cbccb8b8d47a1edc338d4b178e4ebe 110 PRINTS PR00421 Thioredoxin family signature 22 30 7.1E-8 T 14-10-2018 Theos_2029 a1cbccb8b8d47a1edc338d4b178e4ebe 110 PRINTS PR00421 Thioredoxin family signature 30 39 7.1E-8 T 14-10-2018 Theos_2029 a1cbccb8b8d47a1edc338d4b178e4ebe 110 PRINTS PR00421 Thioredoxin family signature 70 81 7.1E-8 T 14-10-2018 Theos_2029 a1cbccb8b8d47a1edc338d4b178e4ebe 110 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Theos_2029 a1cbccb8b8d47a1edc338d4b178e4ebe 110 Pfam PF00085 Thioredoxin 5 105 1.8E-32 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 Theos_2029 a1cbccb8b8d47a1edc338d4b178e4ebe 110 SUPERFAMILY SSF52833 3 108 2.5E-41 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_2029 a1cbccb8b8d47a1edc338d4b178e4ebe 110 Gene3D G3DSA:3.40.30.10 2 110 2.0E-37 T 14-10-2018 Theos_2029 a1cbccb8b8d47a1edc338d4b178e4ebe 110 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 4.5E-39 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Theos_2029 a1cbccb8b8d47a1edc338d4b178e4ebe 110 PIRSF PIRSF000077 1 106 3.1E-41 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Theos_2511 2bc5b74f66f5fbdaeee6b02e3174bfaa 221 Pfam PF02517 CAAX protease self-immunity 121 211 1.3E-4 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 Theos_0722 8f4bd50f991d82e55c46eeddc8a2b24a 159 SMART SM00903 10 157 4.6E-31 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Theos_0722 8f4bd50f991d82e55c46eeddc8a2b24a 159 SUPERFAMILY SSF50475 1 157 7.36E-40 T 14-10-2018 Theos_0722 8f4bd50f991d82e55c46eeddc8a2b24a 159 Pfam PF01613 Flavin reductase like domain 11 155 4.2E-28 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Theos_0722 8f4bd50f991d82e55c46eeddc8a2b24a 159 Gene3D G3DSA:2.30.110.10 1 159 1.6E-38 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Theos_1434 76a1907b8b00232681a72257003e7a1e 205 Pfam PF03167 Uracil DNA glycosylase superfamily 27 165 2.3E-48 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Theos_1434 76a1907b8b00232681a72257003e7a1e 205 Gene3D G3DSA:3.40.470.10 1 205 9.5E-84 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Theos_1434 76a1907b8b00232681a72257003e7a1e 205 SMART SM00986 27 179 3.2E-42 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Theos_1434 76a1907b8b00232681a72257003e7a1e 205 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 13 174 5.7E-60 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 Theos_1434 76a1907b8b00232681a72257003e7a1e 205 SUPERFAMILY SSF52141 2 186 2.26E-69 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Theos_1434 76a1907b8b00232681a72257003e7a1e 205 SMART SM00987 27 179 3.2E-42 T 14-10-2018 Theos_1575 12dd5c8eea251fc0bd05434f75671311 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Theos_1575 12dd5c8eea251fc0bd05434f75671311 344 Gene3D G3DSA:3.90.180.10 14 332 1.8E-97 T 14-10-2018 Theos_1575 12dd5c8eea251fc0bd05434f75671311 344 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 1.8E-10 T 14-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated Theos_1575 12dd5c8eea251fc0bd05434f75671311 344 SUPERFAMILY SSF50129 1 163 1.31E-44 T 14-10-2018 IPR011032 GroES-like superfamily Theos_1575 12dd5c8eea251fc0bd05434f75671311 344 Pfam PF00107 Zinc-binding dehydrogenase 177 301 1.2E-18 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Theos_1575 12dd5c8eea251fc0bd05434f75671311 344 SUPERFAMILY SSF51735 140 310 4.19E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1575 12dd5c8eea251fc0bd05434f75671311 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 133 5.1E-25 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Theos_1575 12dd5c8eea251fc0bd05434f75671311 344 Gene3D G3DSA:3.40.50.720 156 290 1.8E-97 T 14-10-2018 Theos_1819 b528c131f1c352695b1e07b9266a222a 331 SUPERFAMILY SSF55347 132 290 3.92E-41 T 14-10-2018 Theos_1819 b528c131f1c352695b1e07b9266a222a 331 Pfam PF00742 Homoserine dehydrogenase 134 302 1.8E-50 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Theos_1819 b528c131f1c352695b1e07b9266a222a 331 SUPERFAMILY SSF51735 1 149 1.77E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1819 b528c131f1c352695b1e07b9266a222a 331 PIRSF PIRSF036497 1 312 1.2E-78 T 14-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Theos_1819 b528c131f1c352695b1e07b9266a222a 331 Gene3D G3DSA:3.30.360.10 138 286 2.1E-103 T 14-10-2018 Theos_1819 b528c131f1c352695b1e07b9266a222a 331 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 115 3.6E-10 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Theos_1819 b528c131f1c352695b1e07b9266a222a 331 Gene3D G3DSA:3.40.50.720 4 303 2.1E-103 T 14-10-2018 Theos_1819 b528c131f1c352695b1e07b9266a222a 331 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 173 195 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Theos_1251 65802be3674145220dffdefeb87999c2 345 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 1 344 47.032 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 Theos_1251 65802be3674145220dffdefeb87999c2 345 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 341 2.4E-129 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Theos_1251 65802be3674145220dffdefeb87999c2 345 SMART SM01329 2 340 6.5E-184 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Theos_1251 65802be3674145220dffdefeb87999c2 345 SUPERFAMILY SSF53659 2 344 3.06E-120 T 14-10-2018 Theos_1251 65802be3674145220dffdefeb87999c2 345 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 2 343 3.2E-158 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 Theos_1251 65802be3674145220dffdefeb87999c2 345 Gene3D G3DSA:3.40.718.10 1 345 2.2E-155 T 14-10-2018 Theos_1251 65802be3674145220dffdefeb87999c2 345 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 237 256 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 Theos_1124 7afd64aed7fa813280c8c4f5f11ed955 284 ProSitePatterns PS01347 MraY family signature 1. 39 51 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1124 7afd64aed7fa813280c8c4f5f11ed955 284 Pfam PF00953 Glycosyl transferase family 4 69 208 2.0E-26 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 Theos_1124 7afd64aed7fa813280c8c4f5f11ed955 284 ProSitePatterns PS01348 MraY family signature 2. 139 150 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1124 7afd64aed7fa813280c8c4f5f11ed955 284 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 39 51 6.0E-5 T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1124 7afd64aed7fa813280c8c4f5f11ed955 284 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 1 283 17.161 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1546 b864aeef97f89f420f6fdf3be8b66343 372 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 4 369 7.7E-132 T 14-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 Theos_1546 b864aeef97f89f420f6fdf3be8b66343 372 Pfam PF03275 UDP-galactopyranose mutase 151 352 7.5E-76 T 14-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 Theos_1546 b864aeef97f89f420f6fdf3be8b66343 372 Gene3D G3DSA:3.40.50.720 280 371 2.2E-19 T 14-10-2018 Theos_1546 b864aeef97f89f420f6fdf3be8b66343 372 Gene3D G3DSA:3.40.50.720 1 85 6.5E-33 T 14-10-2018 Theos_1546 b864aeef97f89f420f6fdf3be8b66343 372 SUPERFAMILY SSF51971 1 369 5.3E-50 T 14-10-2018 Theos_1546 b864aeef97f89f420f6fdf3be8b66343 372 Gene3D G3DSA:3.40.50.720 166 278 7.4E-29 T 14-10-2018 Theos_1546 b864aeef97f89f420f6fdf3be8b66343 372 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 73 2.0E-15 T 14-10-2018 Theos_1546 b864aeef97f89f420f6fdf3be8b66343 372 SUPERFAMILY SSF54373 250 319 2.94E-19 T 14-10-2018 Theos_2313 1a728cda103eb3b7e3ffe05262864eed 337 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1 334 33.883 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Theos_2313 1a728cda103eb3b7e3ffe05262864eed 337 SUPERFAMILY SSF52733 6 334 1.11E-111 T 14-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Theos_2313 1a728cda103eb3b7e3ffe05262864eed 337 Gene3D G3DSA:1.10.1610.10 12 332 3.5E-134 T 14-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Theos_2313 1a728cda103eb3b7e3ffe05262864eed 337 Pfam PF02277 Phosphoribosyltransferase 2 332 1.2E-125 T 14-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Theos_2313 1a728cda103eb3b7e3ffe05262864eed 337 Gene3D G3DSA:3.40.50.10210 44 316 3.5E-134 T 14-10-2018 Theos_2313 1a728cda103eb3b7e3ffe05262864eed 337 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2 332 1.1E-127 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Theos_2043 8e61919c4c23f55754c1a1bf28561a90 241 SMART SM00382 26 209 6.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2043 8e61919c4c23f55754c1a1bf28561a90 241 Pfam PF00005 ABC transporter 18 161 5.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2043 8e61919c4c23f55754c1a1bf28561a90 241 SUPERFAMILY SSF52540 2 222 4.51E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2043 8e61919c4c23f55754c1a1bf28561a90 241 Gene3D G3DSA:3.40.50.300 1 238 4.5E-62 T 14-10-2018 Theos_0834 e9baedd6a103a695455caaa976eac66a 90 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 4 82 15.549 T 14-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Theos_0834 e9baedd6a103a695455caaa976eac66a 90 Pfam PF09827 CRISPR associated protein Cas2 5 70 1.7E-18 T 14-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 Theos_0834 e9baedd6a103a695455caaa976eac66a 90 Gene3D G3DSA:3.30.70.240 1 90 4.7E-32 T 14-10-2018 Theos_0834 e9baedd6a103a695455caaa976eac66a 90 SUPERFAMILY SSF143430 5 71 1.44E-20 T 14-10-2018 Theos_0834 e9baedd6a103a695455caaa976eac66a 90 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 5 77 8.5E-17 T 14-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Theos_1624 9ccac121dfd9f6435373de04029ef28c 108 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 13 104 1.8E-27 T 14-10-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ Theos_1624 9ccac121dfd9f6435373de04029ef28c 108 Gene3D G3DSA:2.60.40.10 2 108 9.4E-36 T 14-10-2018 IPR013783 Immunoglobulin-like fold Theos_1624 9ccac121dfd9f6435373de04029ef28c 108 SUPERFAMILY SSF81296 10 106 6.02E-25 T 14-10-2018 IPR014756 Immunoglobulin E-set Theos_1624 9ccac121dfd9f6435373de04029ef28c 108 Pfam PF08770 Sulphur oxidation protein SoxZ 14 103 2.3E-25 T 14-10-2018 IPR014880 Sulphur oxidation protein SoxZ Theos_2117 4622a21155527e66066a6b68d56c2922 521 SMART SM01120 34 194 2.7E-61 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 Theos_2117 4622a21155527e66066a6b68d56c2922 521 Gene3D G3DSA:1.25.40.340 6 189 9.4E-9 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 Theos_2117 4622a21155527e66066a6b68d56c2922 521 Pfam PF13684 Dihydroxyacetone kinase family 219 517 3.7E-78 T 14-10-2018 IPR033470 Uncharacterised protein, DhaK domain Theos_2117 4622a21155527e66066a6b68d56c2922 521 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 9 520 2.9E-164 T 14-10-2018 IPR019986 DAK2 domain-containing protein YloV Theos_2117 4622a21155527e66066a6b68d56c2922 521 Pfam PF02734 DAK2 domain 34 193 1.2E-39 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 Theos_2117 4622a21155527e66066a6b68d56c2922 521 SUPERFAMILY SSF101473 6 194 1.57E-41 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 Theos_2117 4622a21155527e66066a6b68d56c2922 521 SMART SM01121 219 521 1.9E-124 T 14-10-2018 IPR033470 Uncharacterised protein, DhaK domain Theos_0241 d1f250f3625f0010c62da28658b9e2c3 318 Pfam PF01063 Amino-transferase class IV 45 275 5.0E-49 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 Theos_0241 d1f250f3625f0010c62da28658b9e2c3 318 SUPERFAMILY SSF56752 16 316 9.03E-100 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 Theos_0241 d1f250f3625f0010c62da28658b9e2c3 318 Gene3D G3DSA:3.20.10.10 141 304 6.1E-53 T 14-10-2018 Theos_0241 d1f250f3625f0010c62da28658b9e2c3 318 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 19 315 7.9E-125 T 14-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 Theos_0241 d1f250f3625f0010c62da28658b9e2c3 318 Gene3D G3DSA:3.30.470.10 15 140 7.4E-46 T 14-10-2018 Theos_1081 ce2f6f8c51843163e601dd2f4f645625 386 Gene3D G3DSA:3.40.710.10 1 367 3.7E-106 T 14-10-2018 Theos_1081 ce2f6f8c51843163e601dd2f4f645625 386 SUPERFAMILY SSF56601 3 363 1.58E-81 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Theos_1081 ce2f6f8c51843163e601dd2f4f645625 386 Pfam PF00144 Beta-lactamase 6 354 3.5E-59 T 14-10-2018 IPR001466 Beta-lactamase-related Theos_1070 ad0a768fc51ae6ce060bb006ebd69c1e 310 SMART SM00327 82 253 2.2E-16 T 14-10-2018 IPR002035 von Willebrand factor, type A Theos_1070 ad0a768fc51ae6ce060bb006ebd69c1e 310 Gene3D G3DSA:3.40.50.410 83 280 2.1E-40 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_1070 ad0a768fc51ae6ce060bb006ebd69c1e 310 Pfam PF13519 von Willebrand factor type A domain 86 188 6.2E-18 T 14-10-2018 IPR002035 von Willebrand factor, type A Theos_1070 ad0a768fc51ae6ce060bb006ebd69c1e 310 SUPERFAMILY SSF53300 86 272 7.46E-31 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_0401 33e1c302f67f5df7f385bcc3fddea67c 248 SUPERFAMILY SSF55120 2 247 5.75E-72 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0401 33e1c302f67f5df7f385bcc3fddea67c 248 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 246 31.711 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0401 33e1c302f67f5df7f385bcc3fddea67c 248 Gene3D G3DSA:3.30.70.660 107 247 2.0E-47 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 Theos_0401 33e1c302f67f5df7f385bcc3fddea67c 248 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 240 2.1E-50 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0401 33e1c302f67f5df7f385bcc3fddea67c 248 Pfam PF01416 tRNA pseudouridine synthase 146 247 2.2E-19 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0401 33e1c302f67f5df7f385bcc3fddea67c 248 PIRSF PIRSF001430 1 248 4.6E-72 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_0401 33e1c302f67f5df7f385bcc3fddea67c 248 Gene3D G3DSA:3.30.70.580 1 105 1.3E-35 T 14-10-2018 Theos_1801 b46cbbb60adee371790c9468b4ab71e4 520 PIRSF PIRSF001363 1 520 1.4E-245 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Theos_1801 b46cbbb60adee371790c9468b4ab71e4 520 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 16 519 3.9E-237 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Theos_1801 b46cbbb60adee371790c9468b4ab71e4 520 Pfam PF01274 Malate synthase 14 519 2.8E-199 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Theos_1801 b46cbbb60adee371790c9468b4ab71e4 520 Gene3D G3DSA:3.20.20.360 4 402 5.8E-188 T 14-10-2018 Theos_1801 b46cbbb60adee371790c9468b4ab71e4 520 ProSitePatterns PS00510 Malate synthase signature. 258 273 - T 14-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Theos_1801 b46cbbb60adee371790c9468b4ab71e4 520 Gene3D G3DSA:1.20.1220.12 405 519 5.5E-43 T 14-10-2018 Theos_1801 b46cbbb60adee371790c9468b4ab71e4 520 SUPERFAMILY SSF51645 15 519 7.06E-186 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Theos_1206 b346c5a29c3cf1f15970168017d1b44a 184 Pfam PF02545 Maf-like protein 5 177 1.1E-51 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Theos_1206 b346c5a29c3cf1f15970168017d1b44a 184 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 177 4.2E-44 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Theos_1206 b346c5a29c3cf1f15970168017d1b44a 184 PIRSF PIRSF006305 1 183 1.8E-48 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Theos_1206 b346c5a29c3cf1f15970168017d1b44a 184 Gene3D G3DSA:3.90.950.10 4 181 4.1E-58 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Theos_1206 b346c5a29c3cf1f15970168017d1b44a 184 Hamap MF_00528 Septum formation protein Maf [maf]. 4 184 29.879 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Theos_1206 b346c5a29c3cf1f15970168017d1b44a 184 SUPERFAMILY SSF52972 3 179 5.17E-53 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Theos_2392 90da4a59f2e859eff0f604d3b7b10762 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 260 7.1E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2392 90da4a59f2e859eff0f604d3b7b10762 271 Gene3D G3DSA:1.10.3720.10 1 258 3.4E-58 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2392 90da4a59f2e859eff0f604d3b7b10762 271 SUPERFAMILY SSF161098 4 271 1.96E-63 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PIRSF PIRSF000350 1 459 6.5E-95 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 SUPERFAMILY SSF51905 3 331 6.8E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 321 1.2E-63 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 Gene3D G3DSA:3.50.50.60 4 327 1.7E-126 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 458 2.1E-156 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 447 3.5E-38 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 1.1E-39 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 1.1E-39 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-39 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 1.1E-39 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 1.1E-39 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 1.1E-75 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 1.1E-75 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 1.1E-75 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 1.1E-75 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 1.1E-75 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 1.1E-75 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 1.1E-75 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.1E-75 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 1.1E-75 T 14-10-2018 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 SUPERFAMILY SSF55424 338 458 1.89E-43 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 Gene3D G3DSA:3.50.50.60 141 264 1.7E-126 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2095 7d97d07b435026babfdc60e8e122d09f 461 Gene3D G3DSA:3.30.390.30 338 461 4.7E-51 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Theos_0598 f50d37e52c6458b394d945f3c0055b7d 518 Pfam PF00999 Sodium/hydrogen exchanger family 4 329 4.4E-27 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Theos_0598 f50d37e52c6458b394d945f3c0055b7d 518 SUPERFAMILY SSF51735 370 498 7.73E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0598 f50d37e52c6458b394d945f3c0055b7d 518 Pfam PF02254 TrkA-N domain 370 485 1.6E-16 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Theos_0598 f50d37e52c6458b394d945f3c0055b7d 518 Gene3D G3DSA:1.20.1530.20 3 344 1.2E-38 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily Theos_0598 f50d37e52c6458b394d945f3c0055b7d 518 Gene3D G3DSA:3.40.50.720 365 504 4.9E-31 T 14-10-2018 Theos_0473 f85ef113e69f200cbc7e91caa321c8a7 363 Gene3D G3DSA:3.40.50.2000 1 191 6.6E-6 T 14-10-2018 Theos_0473 f85ef113e69f200cbc7e91caa321c8a7 363 SUPERFAMILY SSF53756 1 357 1.1E-58 T 14-10-2018 Theos_0473 f85ef113e69f200cbc7e91caa321c8a7 363 Gene3D G3DSA:3.40.50.2000 192 341 3.8E-30 T 14-10-2018 Theos_0473 f85ef113e69f200cbc7e91caa321c8a7 363 Pfam PF00534 Glycosyl transferases group 1 188 340 6.3E-28 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Theos_1024 ea041da017e6cbeefbf3169269899717 508 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 151 249 1.1E-15 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Theos_1024 ea041da017e6cbeefbf3169269899717 508 Gene3D G3DSA:1.20.140.10 256 428 1.2E-33 T 14-10-2018 Theos_1024 ea041da017e6cbeefbf3169269899717 508 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1024 ea041da017e6cbeefbf3169269899717 508 Gene3D G3DSA:2.40.110.20 114 255 3.3E-25 T 14-10-2018 Theos_1024 ea041da017e6cbeefbf3169269899717 508 SUPERFAMILY SSF56645 76 267 7.59E-31 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_1024 ea041da017e6cbeefbf3169269899717 508 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 261 419 2.2E-35 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Theos_1024 ea041da017e6cbeefbf3169269899717 508 SUPERFAMILY SSF47203 260 424 7.25E-33 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_1133 e4b1aacf980834bbd27f26a41827bca9 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 65 81 3.7E-24 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Theos_1133 e4b1aacf980834bbd27f26a41827bca9 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 87 103 3.7E-24 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Theos_1133 e4b1aacf980834bbd27f26a41827bca9 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 111 130 3.7E-24 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Theos_1133 e4b1aacf980834bbd27f26a41827bca9 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 3.7E-24 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Theos_1133 e4b1aacf980834bbd27f26a41827bca9 167 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 143 155 3.7E-24 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Theos_1133 e4b1aacf980834bbd27f26a41827bca9 167 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 158 39.657 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Theos_1133 e4b1aacf980834bbd27f26a41827bca9 167 SUPERFAMILY SSF53098 1 160 9.1E-36 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_1133 e4b1aacf980834bbd27f26a41827bca9 167 Gene3D G3DSA:3.30.420.10 1 167 3.0E-44 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Theos_1133 e4b1aacf980834bbd27f26a41827bca9 167 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 155 2.1E-35 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Theos_0789 dca348db2fca88a73c1543ea99a782e7 211 Gene3D G3DSA:3.20.20.10 2 211 6.7E-67 T 14-10-2018 IPR029066 PLP-binding barrel Theos_0789 dca348db2fca88a73c1543ea99a782e7 211 Pfam PF01168 Alanine racemase, N-terminal domain 8 210 6.3E-23 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Theos_0789 dca348db2fca88a73c1543ea99a782e7 211 PIRSF PIRSF004848 3 211 7.2E-54 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Theos_0789 dca348db2fca88a73c1543ea99a782e7 211 SUPERFAMILY SSF51419 3 209 8.77E-62 T 14-10-2018 IPR029066 PLP-binding barrel Theos_0789 dca348db2fca88a73c1543ea99a782e7 211 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 6 210 1.0E-43 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Theos_0789 dca348db2fca88a73c1543ea99a782e7 211 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 1 211 26.428 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 388 394 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 136 679 4.5E-147 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 Pfam PF00122 E1-E2 ATPase 187 365 3.9E-43 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 386 400 8.4E-22 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 236 250 8.4E-22 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 525 535 8.4E-22 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 602 614 8.4E-22 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 503 514 8.4E-22 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 579 598 8.4E-22 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 159 654 1.0E-60 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 SUPERFAMILY SSF55008 7 72 3.01E-13 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 SUPERFAMILY SSF81653 189 282 3.53E-20 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 Gene3D G3DSA:2.70.150.20 186 290 3.5E-24 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 Pfam PF00403 Heavy-metal-associated domain 7 66 9.7E-11 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 SUPERFAMILY SSF81665 139 380 4.71E-12 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 Pfam PF00702 haloacid dehalogenase-like hydrolase 383 592 1.7E-33 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 Gene3D G3DSA:3.30.70.100 6 71 5.3E-13 T 14-10-2018 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00941 Cadmium-transporting ATPase signature 8 17 4.0E-8 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00941 Cadmium-transporting ATPase signature 19 40 4.0E-8 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00941 Cadmium-transporting ATPase signature 171 191 4.0E-8 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 PRINTS PR00941 Cadmium-transporting ATPase signature 252 268 4.0E-8 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 Gene3D G3DSA:3.40.1110.10 397 510 1.5E-65 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 Gene3D G3DSA:3.40.50.1000 367 627 1.5E-65 T 14-10-2018 IPR023214 HAD superfamily Theos_1460 5cedb04d90f7b0d89428b8b32ba2a66c 684 SUPERFAMILY SSF56784 385 677 1.41E-36 T 14-10-2018 IPR036412 HAD-like superfamily Theos_1625 950fa6bd64eb1ba618e00e2f2b25b09e 150 TIGRFAM TIGR04488 SoxY_true_GGCGG: thiosulfate oxidation carrier protein SoxY 2 150 4.5E-42 T 14-10-2018 IPR016568 Sulphur oxidation, SoxY Theos_1625 950fa6bd64eb1ba618e00e2f2b25b09e 150 Gene3D G3DSA:2.60.40.2470 20 150 2.0E-46 T 14-10-2018 IPR038162 Ig-like SoxY domain superfamily Theos_1625 950fa6bd64eb1ba618e00e2f2b25b09e 150 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 1 26 5.7E-5 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Theos_1625 950fa6bd64eb1ba618e00e2f2b25b09e 150 PIRSF PIRSF010312 1 150 7.9E-46 T 14-10-2018 IPR016568 Sulphur oxidation, SoxY Theos_1625 950fa6bd64eb1ba618e00e2f2b25b09e 150 Pfam PF13501 Sulfur oxidation protein SoxY 51 149 5.9E-30 T 14-10-2018 IPR032711 Ig-like SoxY domain Theos_0562 ef8eeec9bd5db3f52a8ede3acc032a93 464 Pfam PF01523 Putative modulator of DNA gyrase 21 317 1.2E-59 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Theos_0562 ef8eeec9bd5db3f52a8ede3acc032a93 464 PIRSF PIRSF004919 1 464 3.3E-115 T 14-10-2018 IPR025502 TldD Theos_0562 ef8eeec9bd5db3f52a8ede3acc032a93 464 Gene3D G3DSA:3.30.2290.10 3 225 1.3E-23 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Theos_0562 ef8eeec9bd5db3f52a8ede3acc032a93 464 SUPERFAMILY SSF111283 5 463 5.49E-112 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Theos_0616 12c0a0f815962d3b207bf941e522c3f9 265 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 6 220 31.313 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 Theos_0616 12c0a0f815962d3b207bf941e522c3f9 265 SUPERFAMILY SSF69796 1 220 4.18E-71 T 14-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 Theos_0616 12c0a0f815962d3b207bf941e522c3f9 265 Pfam PF02511 Thymidylate synthase complementing protein 12 206 4.0E-56 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 Theos_0616 12c0a0f815962d3b207bf941e522c3f9 265 Gene3D G3DSA:3.30.1360.170 1 227 3.9E-77 T 14-10-2018 Theos_0616 12c0a0f815962d3b207bf941e522c3f9 265 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 10 212 3.4E-64 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 Theos_0803 474a44f01f432ce05fb9c7ed17d7f526 122 Pfam PF01475 Ferric uptake regulator family 3 115 4.0E-20 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Theos_0803 474a44f01f432ce05fb9c7ed17d7f526 122 SUPERFAMILY SSF46785 3 120 1.46E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0803 474a44f01f432ce05fb9c7ed17d7f526 122 Gene3D G3DSA:1.10.10.10 2 71 1.4E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0803 474a44f01f432ce05fb9c7ed17d7f526 122 Gene3D G3DSA:3.30.1490.190 73 122 6.7E-12 T 14-10-2018 Theos_2295 abc1532307cc3629890419a5d1daa514 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 250 1.3E-98 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 Theos_2295 abc1532307cc3629890419a5d1daa514 256 SUPERFAMILY SSF110399 2 240 1.31E-72 T 14-10-2018 Theos_2295 abc1532307cc3629890419a5d1daa514 256 Hamap MF_00443 Thiazole synthase [thiG]. 3 256 41.324 T 14-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 Theos_2295 abc1532307cc3629890419a5d1daa514 256 Gene3D G3DSA:3.20.20.70 1 241 1.1E-105 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1261 fc66a99b42e7793b455c6ee5ceb39b5c 358 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 11 355 1.0E-108 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1261 fc66a99b42e7793b455c6ee5ceb39b5c 358 Pfam PF01098 Cell cycle protein 36 355 3.7E-95 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1261 fc66a99b42e7793b455c6ee5ceb39b5c 358 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 5 358 25.78 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_1261 fc66a99b42e7793b455c6ee5ceb39b5c 358 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 313 337 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Theos_0663 46deaa795afe71f1ea4e448b98877252 257 SUPERFAMILY SSF51621 7 257 3.1E-100 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Theos_0663 46deaa795afe71f1ea4e448b98877252 257 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 9 257 8.2E-103 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Theos_0663 46deaa795afe71f1ea4e448b98877252 257 PIRSF PIRSF000388 1 257 1.8E-105 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Theos_0663 46deaa795afe71f1ea4e448b98877252 257 Gene3D G3DSA:3.20.20.60 2 257 5.2E-111 T 14-10-2018 Theos_0663 46deaa795afe71f1ea4e448b98877252 257 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 1 257 41.912 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Theos_0663 46deaa795afe71f1ea4e448b98877252 257 Pfam PF02548 Ketopantoate hydroxymethyltransferase 6 252 1.3E-105 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Theos_2380 f29e74b77a9dc9bfb97ded9c94d95901 134 SUPERFAMILY SSF75169 1 133 1.03E-16 T 14-10-2018 IPR027396 DsrEFH-like Theos_0108 b1fe6ef83069c42fefeb7e7ff9f2fcf8 209 Gene3D G3DSA:2.102.10.10 46 208 2.1E-57 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Theos_0108 b1fe6ef83069c42fefeb7e7ff9f2fcf8 209 Pfam PF00355 Rieske [2Fe-2S] domain 103 179 4.4E-12 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Theos_0108 b1fe6ef83069c42fefeb7e7ff9f2fcf8 209 PRINTS PR00162 Rieske 2Fe-2S subunit signature 149 161 3.9E-8 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Theos_0108 b1fe6ef83069c42fefeb7e7ff9f2fcf8 209 PRINTS PR00162 Rieske 2Fe-2S subunit signature 163 175 3.9E-8 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Theos_0108 b1fe6ef83069c42fefeb7e7ff9f2fcf8 209 PRINTS PR00162 Rieske 2Fe-2S subunit signature 127 138 3.9E-8 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Theos_0108 b1fe6ef83069c42fefeb7e7ff9f2fcf8 209 SUPERFAMILY SSF50022 60 196 1.07E-31 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Theos_2012 3d13f4dd7b1316153aaea7136403c753 151 Gene3D G3DSA:3.40.1280.10 1 149 7.9E-62 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Theos_2012 3d13f4dd7b1316153aaea7136403c753 151 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 149 33.957 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 Theos_2012 3d13f4dd7b1316153aaea7136403c753 151 PIRSF PIRSF029256 1 151 9.0E-58 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 Theos_2012 3d13f4dd7b1316153aaea7136403c753 151 Pfam PF00588 SpoU rRNA Methylase family 2 140 4.8E-36 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Theos_2012 3d13f4dd7b1316153aaea7136403c753 151 SUPERFAMILY SSF75217 2 147 7.19E-43 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Theos_2451 d68fa3ac38ff15dde30ae2d0aa7be62d 327 Gene3D G3DSA:3.40.190.10 111 259 8.6E-77 T 14-10-2018 Theos_2451 d68fa3ac38ff15dde30ae2d0aa7be62d 327 Pfam PF16868 NMT1-like family 23 324 3.7E-55 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Theos_2451 d68fa3ac38ff15dde30ae2d0aa7be62d 327 SUPERFAMILY SSF53850 20 326 4.53E-52 T 14-10-2018 Theos_2451 d68fa3ac38ff15dde30ae2d0aa7be62d 327 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 17 324 1.4E-62 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Theos_2451 d68fa3ac38ff15dde30ae2d0aa7be62d 327 Gene3D G3DSA:3.40.190.10 23 324 8.6E-77 T 14-10-2018 Theos_1880 ab8af389a5ba19d496e604e91e9d6077 441 Gene3D G3DSA:3.40.50.2000 6 436 2.2E-141 T 14-10-2018 Theos_1880 ab8af389a5ba19d496e604e91e9d6077 441 Gene3D G3DSA:3.40.50.2000 230 421 2.2E-141 T 14-10-2018 Theos_1880 ab8af389a5ba19d496e604e91e9d6077 441 Pfam PF08323 Starch synthase catalytic domain 5 216 7.6E-60 T 14-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 Theos_1880 ab8af389a5ba19d496e604e91e9d6077 441 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 5 438 4.9E-145 T 14-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 Theos_1880 ab8af389a5ba19d496e604e91e9d6077 441 Hamap MF_00484 Glycogen synthase [glgA]. 4 439 41.244 T 14-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 Theos_1880 ab8af389a5ba19d496e604e91e9d6077 441 SUPERFAMILY SSF53756 5 440 3.84E-107 T 14-10-2018 Theos_1880 ab8af389a5ba19d496e604e91e9d6077 441 Pfam PF00534 Glycosyl transferases group 1 267 398 2.0E-16 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Theos_2473 24f6e360c852e1f99875e9026bf21a64 347 SUPERFAMILY SSF51569 8 280 7.69E-70 T 14-10-2018 Theos_2473 24f6e360c852e1f99875e9026bf21a64 347 Gene3D G3DSA:3.20.20.70 11 272 2.0E-89 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_2473 24f6e360c852e1f99875e9026bf21a64 347 Gene3D G3DSA:1.10.8.60 280 344 5.8E-24 T 14-10-2018 Theos_2473 24f6e360c852e1f99875e9026bf21a64 347 Pfam PF07836 DmpG-like communication domain 279 338 2.8E-26 T 14-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 Theos_2473 24f6e360c852e1f99875e9026bf21a64 347 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 11 340 2.4E-159 T 14-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 Theos_2473 24f6e360c852e1f99875e9026bf21a64 347 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 347 168.936 T 14-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 Theos_2473 24f6e360c852e1f99875e9026bf21a64 347 SUPERFAMILY SSF89000 292 340 1.61E-15 T 14-10-2018 Theos_2473 24f6e360c852e1f99875e9026bf21a64 347 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 280 340 4.0E-27 T 14-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 Theos_2473 24f6e360c852e1f99875e9026bf21a64 347 Pfam PF00682 HMGL-like 13 268 5.0E-60 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Theos_2393 62f47ec51a963df2256f23a9d97b6623 286 SUPERFAMILY SSF56300 1 253 3.16E-49 T 14-10-2018 Theos_2393 62f47ec51a963df2256f23a9d97b6623 286 Gene3D G3DSA:3.60.21.10 1 267 1.7E-73 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_2393 62f47ec51a963df2256f23a9d97b6623 286 Pfam PF13277 YmdB-like protein 4 250 5.6E-59 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 SUPERFAMILY SSF50249 128 264 2.78E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 Hamap MF_00984 Single-stranded DNA-binding protein. 128 231 24.567 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 Gene3D G3DSA:2.40.50.140 127 235 5.1E-38 T 14-10-2018 Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 126 225 1.5E-26 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 110 9.6E-29 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 Gene3D G3DSA:2.40.50.140 1 126 1.7E-40 T 14-10-2018 Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 Pfam PF00436 Single-strand binding protein family 128 225 5.8E-24 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 Pfam PF00436 Single-strand binding protein family 5 105 1.4E-27 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 Hamap MF_00984 Single-stranded DNA-binding protein. 5 111 23.952 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Theos_2123 53a3492ba68454b40714cc74e48b7eed 264 SUPERFAMILY SSF50249 3 122 2.43E-32 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0306 791b64ce4c1bece393002e8b7b21d8e6 118 Gene3D G3DSA:3.90.1030.10 1 118 1.5E-50 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0306 791b64ce4c1bece393002e8b7b21d8e6 118 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 118 3.3E-41 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0306 791b64ce4c1bece393002e8b7b21d8e6 118 Pfam PF01196 Ribosomal protein L17 20 117 1.4E-35 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0306 791b64ce4c1bece393002e8b7b21d8e6 118 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 117 26.089 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0306 791b64ce4c1bece393002e8b7b21d8e6 118 SUPERFAMILY SSF64263 1 117 3.01E-45 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0540 d817cc16718aa6942e25c8f87023f127 954 SUPERFAMILY SSF117074 680 739 1.7E-7 T 14-10-2018 Theos_0540 d817cc16718aa6942e25c8f87023f127 954 SUPERFAMILY SSF117074 589 654 9.29E-6 T 14-10-2018 Theos_0540 d817cc16718aa6942e25c8f87023f127 954 Gene3D G3DSA:2.60.40.10 678 752 8.0E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold Theos_0540 d817cc16718aa6942e25c8f87023f127 954 Gene3D G3DSA:2.60.40.10 591 665 5.1E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold Theos_2428 8bf31c6b1c98afb105907b6507539047 521 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 434 2.2E-79 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain Theos_2428 8bf31c6b1c98afb105907b6507539047 521 Gene3D G3DSA:3.90.76.10 36 200 1.4E-115 T 14-10-2018 Theos_2428 8bf31c6b1c98afb105907b6507539047 521 SUPERFAMILY SSF53850 22 519 1.41E-112 T 14-10-2018 Theos_2428 8bf31c6b1c98afb105907b6507539047 521 PIRSF PIRSF002741 16 519 2.7E-79 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Theos_2428 8bf31c6b1c98afb105907b6507539047 521 Gene3D G3DSA:3.40.190.10 201 504 1.4E-115 T 14-10-2018 Theos_2428 8bf31c6b1c98afb105907b6507539047 521 Gene3D G3DSA:3.10.105.10 279 496 1.4E-115 T 14-10-2018 Theos_1403 95ed25bb0c537fafce687492a7870d62 192 Gene3D G3DSA:3.30.60.20 143 192 6.6E-24 T 14-10-2018 Theos_1403 95ed25bb0c537fafce687492a7870d62 192 Gene3D G3DSA:3.40.50.300 3 142 7.3E-53 T 14-10-2018 Theos_1403 95ed25bb0c537fafce687492a7870d62 192 PIRSF PIRSF035805 6 191 7.4E-60 T 14-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 Theos_1403 95ed25bb0c537fafce687492a7870d62 192 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 175 188 - T 14-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 Theos_1403 95ed25bb0c537fafce687492a7870d62 192 Hamap MF_00124 Thymidine kinase [tdk]. 8 191 36.144 T 14-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 Theos_1403 95ed25bb0c537fafce687492a7870d62 192 SUPERFAMILY SSF52540 9 143 3.32E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1403 95ed25bb0c537fafce687492a7870d62 192 SUPERFAMILY SSF57716 143 190 1.11E-15 T 14-10-2018 Theos_1403 95ed25bb0c537fafce687492a7870d62 192 Pfam PF00265 Thymidine kinase 9 188 5.6E-50 T 14-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 Theos_1998 76c52557a9adbbb40172953b05608f83 615 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 608 41.772 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Theos_1998 76c52557a9adbbb40172953b05608f83 615 ProSitePatterns PS00802 Transketolase signature 2. 415 431 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Theos_1998 76c52557a9adbbb40172953b05608f83 615 Pfam PF02779 Transketolase, pyrimidine binding domain 309 471 7.4E-41 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_1998 76c52557a9adbbb40172953b05608f83 615 Gene3D G3DSA:3.40.50.970 306 483 2.3E-70 T 14-10-2018 Theos_1998 76c52557a9adbbb40172953b05608f83 615 Gene3D G3DSA:3.40.50.920 484 612 1.6E-40 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_1998 76c52557a9adbbb40172953b05608f83 615 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 275 2.9E-111 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Theos_1998 76c52557a9adbbb40172953b05608f83 615 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 604 9.0E-217 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Theos_1998 76c52557a9adbbb40172953b05608f83 615 SMART SM00861 309 473 3.7E-63 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Theos_1998 76c52557a9adbbb40172953b05608f83 615 SUPERFAMILY SSF52518 307 493 9.29E-56 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_1998 76c52557a9adbbb40172953b05608f83 615 SUPERFAMILY SSF52518 3 371 6.08E-70 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_1998 76c52557a9adbbb40172953b05608f83 615 Pfam PF02780 Transketolase, C-terminal domain 484 599 1.1E-23 T 14-10-2018 IPR033248 Transketolase, C-terminal domain Theos_1998 76c52557a9adbbb40172953b05608f83 615 SUPERFAMILY SSF52922 480 606 4.32E-27 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Theos_1568 04dea53366e76c05250739ea990be63b 392 SUPERFAMILY SSF53383 5 390 4.57E-112 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_1568 04dea53366e76c05250739ea990be63b 392 Gene3D G3DSA:3.40.640.10 55 290 8.3E-137 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_1568 04dea53366e76c05250739ea990be63b 392 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 237 246 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 Theos_1568 04dea53366e76c05250739ea990be63b 392 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 392 1.3E-179 T 14-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type Theos_1568 04dea53366e76c05250739ea990be63b 392 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 24 380 2.8E-130 T 14-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 Theos_1568 04dea53366e76c05250739ea990be63b 392 Gene3D G3DSA:3.90.1150.10 35 383 8.3E-137 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_1568 04dea53366e76c05250739ea990be63b 392 Pfam PF00155 Aminotransferase class I and II 40 380 4.1E-65 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Theos_1468 bee142882277674fe5e432c6d5102ef8 507 SUPERFAMILY SSF52540 53 270 4.59E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1468 bee142882277674fe5e432c6d5102ef8 507 Pfam PF05970 PIF1-like helicase 68 276 5.7E-26 T 14-10-2018 IPR010285 DNA helicase Pif1-like GO:0000723|GO:0003678|GO:0006281 Theos_1468 bee142882277674fe5e432c6d5102ef8 507 Gene3D G3DSA:3.40.50.300 44 272 5.2E-29 T 14-10-2018 Theos_1468 bee142882277674fe5e432c6d5102ef8 507 SUPERFAMILY SSF52540 195 476 1.33E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1468 bee142882277674fe5e432c6d5102ef8 507 Gene3D G3DSA:2.30.30.940 338 392 3.6E-5 T 14-10-2018 Theos_1468 bee142882277674fe5e432c6d5102ef8 507 Gene3D G3DSA:3.40.50.300 393 474 4.7E-5 T 14-10-2018 Theos_0228 9143aaeca6bd6dba57e8fe35561de9e2 124 Pfam PF01042 Endoribonuclease L-PSP 7 122 7.2E-43 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 Theos_0228 9143aaeca6bd6dba57e8fe35561de9e2 124 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 122 1.2E-49 T 14-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 Theos_0228 9143aaeca6bd6dba57e8fe35561de9e2 124 SUPERFAMILY SSF55298 2 122 1.48E-46 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Theos_0228 9143aaeca6bd6dba57e8fe35561de9e2 124 Gene3D G3DSA:3.30.1330.40 1 124 5.1E-57 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Theos_2447 16013ac07888afdbf97904be591b0a99 494 Gene3D G3DSA:3.10.105.10 266 460 1.9E-44 T 14-10-2018 Theos_2447 16013ac07888afdbf97904be591b0a99 494 PIRSF PIRSF002741 14 494 3.2E-101 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Theos_2447 16013ac07888afdbf97904be591b0a99 494 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 66 402 7.6E-91 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain Theos_2447 16013ac07888afdbf97904be591b0a99 494 Gene3D G3DSA:3.40.190.10 12 265 4.1E-69 T 14-10-2018 Theos_2447 16013ac07888afdbf97904be591b0a99 494 SUPERFAMILY SSF53850 18 481 1.81E-131 T 14-10-2018 Theos_0676 ebc5d1b633c85b5e4ed0bfe059d06505 289 PRINTS PR00116 Arginase signature 211 240 2.9E-33 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Theos_0676 ebc5d1b633c85b5e4ed0bfe059d06505 289 PRINTS PR00116 Arginase signature 246 260 2.9E-33 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Theos_0676 ebc5d1b633c85b5e4ed0bfe059d06505 289 PRINTS PR00116 Arginase signature 164 182 2.9E-33 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Theos_0676 ebc5d1b633c85b5e4ed0bfe059d06505 289 PRINTS PR00116 Arginase signature 92 107 2.9E-33 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Theos_0676 ebc5d1b633c85b5e4ed0bfe059d06505 289 Pfam PF00491 Arginase family 3 284 1.3E-78 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Theos_0676 ebc5d1b633c85b5e4ed0bfe059d06505 289 Gene3D G3DSA:3.40.800.10 2 289 2.2E-120 T 14-10-2018 Theos_0676 ebc5d1b633c85b5e4ed0bfe059d06505 289 SUPERFAMILY SSF52768 3 287 2.16E-91 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily Theos_0676 ebc5d1b633c85b5e4ed0bfe059d06505 289 PIRSF PIRSF036979 2 285 2.3E-37 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Theos_0676 ebc5d1b633c85b5e4ed0bfe059d06505 289 TIGRFAM TIGR01229 rocF_arginase: arginase 6 287 1.4E-90 T 14-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 Theos_1492 d5a0fc6e43152180b7c2661002c8d653 294 Pfam PF12146 Serine aminopeptidase, S33 73 188 2.2E-11 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 Theos_1492 d5a0fc6e43152180b7c2661002c8d653 294 SUPERFAMILY SSF53474 21 293 3.68E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1492 d5a0fc6e43152180b7c2661002c8d653 294 Gene3D G3DSA:3.40.50.1820 22 293 8.3E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_0788 25e15e1e06c6da0457203b30856a6b7a 272 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 23 269 3.3E-90 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 Theos_0788 25e15e1e06c6da0457203b30856a6b7a 272 Gene3D G3DSA:3.40.50.1580 2 270 2.2E-100 T 14-10-2018 Theos_0788 25e15e1e06c6da0457203b30856a6b7a 272 Pfam PF01048 Phosphorylase superfamily 24 269 4.6E-43 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Theos_0788 25e15e1e06c6da0457203b30856a6b7a 272 PIRSF PIRSF000477 2 272 7.3E-95 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 Theos_0788 25e15e1e06c6da0457203b30856a6b7a 272 SUPERFAMILY SSF53167 3 272 3.2E-84 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Theos_0788 25e15e1e06c6da0457203b30856a6b7a 272 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 24 269 2.5E-90 T 14-10-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 Theos_2109 c20907a18ebbf9008ae8bdc127c39cd1 295 Pfam PF00248 Aldo/keto reductase family 8 293 5.8E-56 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain Theos_2109 c20907a18ebbf9008ae8bdc127c39cd1 295 SUPERFAMILY SSF51430 8 294 2.88E-71 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Theos_2109 c20907a18ebbf9008ae8bdc127c39cd1 295 PRINTS PR00069 Aldo-keto reductase signature 129 146 2.7E-8 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Theos_2109 c20907a18ebbf9008ae8bdc127c39cd1 295 PRINTS PR00069 Aldo-keto reductase signature 40 64 2.7E-8 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Theos_2109 c20907a18ebbf9008ae8bdc127c39cd1 295 PRINTS PR00069 Aldo-keto reductase signature 98 116 2.7E-8 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Theos_2109 c20907a18ebbf9008ae8bdc127c39cd1 295 Gene3D G3DSA:3.20.20.100 4 295 3.5E-73 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Theos_0619 4acb83e3301a0ef101718c30a1073f2c 377 Pfam PF04055 Radical SAM superfamily 54 221 6.5E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_0619 4acb83e3301a0ef101718c30a1073f2c 377 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 10 360 50.078 T 14-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 Theos_0619 4acb83e3301a0ef101718c30a1073f2c 377 SUPERFAMILY SSF102114 10 350 3.92E-47 T 14-10-2018 Theos_0619 4acb83e3301a0ef101718c30a1073f2c 377 PIRSF PIRSF004762 1 369 2.1E-94 T 14-10-2018 Theos_0619 4acb83e3301a0ef101718c30a1073f2c 377 Gene3D G3DSA:3.20.20.70 1 347 1.2E-42 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0619 4acb83e3301a0ef101718c30a1073f2c 377 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 46 357 6.2E-95 T 14-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 Theos_0529 79409d29abadc3eadb9abdd6cf5972d1 399 SUPERFAMILY SSF103473 13 384 4.19E-45 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_0529 79409d29abadc3eadb9abdd6cf5972d1 399 Gene3D G3DSA:1.20.1250.20 14 385 4.0E-39 T 14-10-2018 Theos_0529 79409d29abadc3eadb9abdd6cf5972d1 399 Pfam PF05977 Transmembrane secretion effector 7 385 1.6E-54 T 14-10-2018 IPR010290 Transmembrane secretion effector Theos_0665 77d88f7027ddb0410aa275b702b7a888 290 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 39 44 - T 14-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 Theos_0665 77d88f7027ddb0410aa275b702b7a888 290 Gene3D G3DSA:3.40.50.150 15 276 2.6E-81 T 14-10-2018 Theos_0665 77d88f7027ddb0410aa275b702b7a888 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 228 246 2.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Theos_0665 77d88f7027ddb0410aa275b702b7a888 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 34 48 2.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Theos_0665 77d88f7027ddb0410aa275b702b7a888 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 73 93 2.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Theos_0665 77d88f7027ddb0410aa275b702b7a888 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 209 226 2.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Theos_0665 77d88f7027ddb0410aa275b702b7a888 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 251 271 2.4E-28 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Theos_0665 77d88f7027ddb0410aa275b702b7a888 290 SUPERFAMILY SSF53335 14 271 1.57E-56 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0665 77d88f7027ddb0410aa275b702b7a888 290 Pfam PF01555 DNA methylase 37 268 2.6E-34 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 Theos_1028 fc1b7e12279601250c20a9ee412ca197 99 SUPERFAMILY SSF117916 1 98 3.27E-32 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Theos_1028 fc1b7e12279601250c20a9ee412ca197 99 Pfam PF01883 Iron-sulfur cluster assembly protein 4 76 4.6E-24 T 14-10-2018 IPR002744 MIP18 family-like Theos_1028 fc1b7e12279601250c20a9ee412ca197 99 Gene3D G3DSA:3.30.300.130 1 99 3.1E-37 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Theos_1276 c564b3d4f40f0021a637efaa414fd0cf 733 Pfam PF00271 Helicase conserved C-terminal domain 282 379 6.1E-15 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1276 c564b3d4f40f0021a637efaa414fd0cf 733 Gene3D G3DSA:3.40.50.300 51 238 3.3E-36 T 14-10-2018 Theos_1276 c564b3d4f40f0021a637efaa414fd0cf 733 SMART SM00490 300 379 2.6E-18 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1276 c564b3d4f40f0021a637efaa414fd0cf 733 SUPERFAMILY SSF52540 66 389 1.72E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1276 c564b3d4f40f0021a637efaa414fd0cf 733 SMART SM00487 53 254 1.3E-27 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_1276 c564b3d4f40f0021a637efaa414fd0cf 733 Pfam PF00270 DEAD/DEAH box helicase 59 225 1.3E-22 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Theos_1276 c564b3d4f40f0021a637efaa414fd0cf 733 Gene3D G3DSA:3.40.50.300 262 407 3.5E-25 T 14-10-2018 Theos_1276 c564b3d4f40f0021a637efaa414fd0cf 733 Pfam PF09369 Domain of unknown function (DUF1998) 616 699 3.3E-21 T 14-10-2018 IPR018973 DEAD/DEAH-box helicase, putative Theos_1988 f09de443389c12a01dc0a9365e445e76 150 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 124 3.2E-19 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Theos_1988 f09de443389c12a01dc0a9365e445e76 150 SUPERFAMILY SSF52788 1 129 5.76E-34 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Theos_1988 f09de443389c12a01dc0a9365e445e76 150 Gene3D G3DSA:3.40.50.2300 1 128 1.4E-36 T 14-10-2018 Theos_1988 f09de443389c12a01dc0a9365e445e76 150 SMART SM00226 1 132 3.5E-29 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Theos_0370 e7c340c6d44f5bb9d52c42e42ef21894 294 Gene3D G3DSA:3.40.50.300 1 180 7.1E-50 T 14-10-2018 Theos_0370 e7c340c6d44f5bb9d52c42e42ef21894 294 SUPERFAMILY SSF52540 2 266 7.08E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0370 e7c340c6d44f5bb9d52c42e42ef21894 294 PIRSF PIRSF002849 1 294 3.8E-105 T 14-10-2018 Theos_0370 e7c340c6d44f5bb9d52c42e42ef21894 294 Gene3D G3DSA:1.10.8.300 185 290 1.6E-15 T 14-10-2018 Theos_0370 e7c340c6d44f5bb9d52c42e42ef21894 294 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 31 158 2.0E-58 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Theos_0370 e7c340c6d44f5bb9d52c42e42ef21894 294 SMART SM00382 28 167 1.5E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0041 e8c5e2ac7784d1d86212e07ccf7b25d4 431 SUPERFAMILY SSF56349 70 373 1.27E-62 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Theos_0041 e8c5e2ac7784d1d86212e07ccf7b25d4 431 Gene3D G3DSA:1.10.150.130 64 184 6.9E-17 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Theos_0041 e8c5e2ac7784d1d86212e07ccf7b25d4 431 Pfam PF00589 Phage integrase family 187 368 7.1E-30 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Theos_0041 e8c5e2ac7784d1d86212e07ccf7b25d4 431 Gene3D G3DSA:1.10.443.10 185 382 5.3E-50 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Theos_1561 dc94bd6df86b795c2276b8e89b8deb09 122 Gene3D G3DSA:3.30.1330.40 1 122 1.5E-52 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Theos_1561 dc94bd6df86b795c2276b8e89b8deb09 122 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 2 118 2.0E-42 T 14-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Theos_1561 dc94bd6df86b795c2276b8e89b8deb09 122 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 8 121 3.0E-54 T 14-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Theos_1561 dc94bd6df86b795c2276b8e89b8deb09 122 SUPERFAMILY SSF55298 1 118 2.43E-46 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Theos_1561 dc94bd6df86b795c2276b8e89b8deb09 122 Pfam PF07736 Chorismate mutase type I 2 118 4.5E-45 T 14-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Theos_1561 dc94bd6df86b795c2276b8e89b8deb09 122 PIRSF PIRSF005965 1 122 7.1E-48 T 14-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Theos_2228 7fa13b8555fb9800b4c1e07904972125 306 SUPERFAMILY SSF51556 16 297 1.42E-27 T 14-10-2018 IPR032466 Metal-dependent hydrolase Theos_2228 7fa13b8555fb9800b4c1e07904972125 306 Gene3D G3DSA:3.20.20.140 156 300 2.4E-8 T 14-10-2018 Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 Pfam PF02817 e3 binding domain 97 132 4.7E-13 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 SUPERFAMILY SSF47005 93 136 4.97E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 Gene3D G3DSA:2.40.50.100 1 95 3.3E-20 T 14-10-2018 Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 Gene3D G3DSA:3.30.559.10 167 398 8.9E-96 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 SUPERFAMILY SSF52777 170 397 9.34E-89 T 14-10-2018 Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 Gene3D G3DSA:4.10.320.10 96 138 2.1E-13 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 398 6.6E-147 T 14-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 SUPERFAMILY SSF51230 2 93 5.89E-22 T 14-10-2018 IPR011053 Single hybrid motif Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 169 396 5.4E-82 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 Pfam PF00364 Biotin-requiring enzyme 3 74 1.4E-15 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Theos_0132 1e4994167b2d04bcc7c8fe2f4320434c 398 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Theos_0842 80a73eef4406adcf996e950584ee70fc 247 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0842 80a73eef4406adcf996e950584ee70fc 247 Gene3D G3DSA:3.40.50.300 4 247 3.1E-86 T 14-10-2018 Theos_0842 80a73eef4406adcf996e950584ee70fc 247 SUPERFAMILY SSF52540 7 240 3.59E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0842 80a73eef4406adcf996e950584ee70fc 247 SMART SM00382 32 218 1.4E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0842 80a73eef4406adcf996e950584ee70fc 247 PIRSF PIRSF039085 4 246 6.3E-119 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 Theos_0842 80a73eef4406adcf996e950584ee70fc 247 Pfam PF00005 ABC transporter 23 170 3.0E-40 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0149 a972fd5077b22973d1b99b739deee247 1048 SUPERFAMILY SSF117074 748 834 9.94E-5 T 14-10-2018 Theos_1886 ea3f1af2fb26329cd7b29414aaee8296 329 Pfam PF00348 Polyprenyl synthetase 27 272 3.1E-45 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 Theos_1886 ea3f1af2fb26329cd7b29414aaee8296 329 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 90 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site Theos_1886 ea3f1af2fb26329cd7b29414aaee8296 329 SUPERFAMILY SSF48576 19 328 1.96E-60 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Theos_1886 ea3f1af2fb26329cd7b29414aaee8296 329 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 204 216 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site Theos_1886 ea3f1af2fb26329cd7b29414aaee8296 329 Gene3D G3DSA:1.10.600.10 1 329 3.4E-106 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Theos_1843 21f1a26c0291733bbe1bae9306f83650 349 Pfam PF07690 Major Facilitator Superfamily 6 317 7.4E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_1843 21f1a26c0291733bbe1bae9306f83650 349 SUPERFAMILY SSF103473 3 345 1.44E-24 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1843 21f1a26c0291733bbe1bae9306f83650 349 Gene3D G3DSA:1.20.1250.20 2 348 1.4E-18 T 14-10-2018 Theos_1193 4ac0c17e9e37e87fae93cab33d895a85 289 Pfam PF13464 Domain of unknown function (DUF4115) 215 284 8.9E-11 T 14-10-2018 IPR025194 Domain of unknown function DUF4115 Theos_1193 4ac0c17e9e37e87fae93cab33d895a85 289 Pfam PF08308 PEGA domain 129 192 2.3E-15 T 14-10-2018 IPR013229 PEGA Theos_1193 4ac0c17e9e37e87fae93cab33d895a85 289 Gene3D G3DSA:1.10.260.40 1 85 3.4E-25 T 14-10-2018 Theos_1193 4ac0c17e9e37e87fae93cab33d895a85 289 SMART SM00530 7 68 0.0029 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Theos_1193 4ac0c17e9e37e87fae93cab33d895a85 289 Pfam PF13413 Helix-turn-helix domain 7 68 3.3E-22 T 14-10-2018 Theos_1193 4ac0c17e9e37e87fae93cab33d895a85 289 SUPERFAMILY SSF47413 3 71 1.41E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Theos_0882 382102b4212beabcc351312c1db55c08 252 Gene3D G3DSA:3.60.21.10 1 252 8.1E-103 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_0882 382102b4212beabcc351312c1db55c08 252 Pfam PF13277 YmdB-like protein 4 238 6.7E-87 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like Theos_0882 382102b4212beabcc351312c1db55c08 252 SMART SM00854 2 180 0.0037 T 14-10-2018 IPR019079 Capsule synthesis protein, CapA Theos_0882 382102b4212beabcc351312c1db55c08 252 SUPERFAMILY SSF56300 1 238 2.44E-76 T 14-10-2018 Theos_0882 382102b4212beabcc351312c1db55c08 252 PIRSF PIRSF004789 1 249 1.5E-77 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 Gene3D G3DSA:3.10.50.40 149 225 1.7E-42 T 14-10-2018 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 TIGRFAM TIGR00115 tig: trigger factor 12 397 6.3E-89 T 14-10-2018 IPR005215 Trigger factor GO:0015031 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 SUPERFAMILY SSF54534 97 201 5.36E-8 T 14-10-2018 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 239 398 5.5E-30 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 Gene3D G3DSA:3.30.70.1050 1 112 6.8E-30 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 Pfam PF05697 Bacterial trigger factor protein (TF) 8 143 6.6E-34 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 Gene3D G3DSA:1.10.3120.10 113 400 1.7E-42 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 Hamap MF_00303 Trigger factor [tig]. 1 399 16.057 T 14-10-2018 IPR005215 Trigger factor GO:0015031 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 PIRSF PIRSF003095 2 402 1.3E-77 T 14-10-2018 IPR005215 Trigger factor GO:0015031 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 SUPERFAMILY SSF102735 6 126 1.7E-28 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 Theos_1348 f9ad22eae04d0372d1b5f64836b7f1a0 404 SUPERFAMILY SSF109998 227 398 3.79E-30 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily Theos_2247 780010be2a80ef96ddb7c8c805b4e49d 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.3E-15 T 14-10-2018 IPR032806 H repeat-associated protein, N-terminal Theos_2368 780010be2a80ef96ddb7c8c805b4e49d 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.3E-15 T 14-10-2018 IPR032806 H repeat-associated protein, N-terminal Theos_1788 a72d619a3f1669b4b53f1e50aceba935 317 Gene3D G3DSA:3.60.15.10 1 261 1.0E-80 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1788 a72d619a3f1669b4b53f1e50aceba935 317 SUPERFAMILY SSF56281 3 307 3.93E-61 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1788 a72d619a3f1669b4b53f1e50aceba935 317 Gene3D G3DSA:1.10.10.10 262 317 4.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1788 a72d619a3f1669b4b53f1e50aceba935 317 Pfam PF00753 Metallo-beta-lactamase superfamily 21 233 1.0E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_1788 a72d619a3f1669b4b53f1e50aceba935 317 SMART SM00849 21 233 5.4E-29 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 SUPERFAMILY SSF69864 169 394 6.67E-96 T 14-10-2018 Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 Pfam PF00764 Arginosuccinate synthase 4 389 6.2E-164 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 Gene3D G3DSA:1.20.5.470 370 400 9.2E-17 T 14-10-2018 Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 114 125 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 Gene3D G3DSA:3.90.1260.10 61 351 3.5E-165 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 Gene3D G3DSA:3.40.50.620 3 170 3.5E-165 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 395 53.968 T 14-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 389 3.4E-157 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Theos_0130 1140bfd1b1315bf9dcf0639be343e5cf 400 SUPERFAMILY SSF52402 1 203 4.85E-52 T 14-10-2018 Theos_1393 1ceba61d4190a135fe726c7061f73ff5 124 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 71 79 9.5E-8 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Theos_1393 1ceba61d4190a135fe726c7061f73ff5 124 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 81 90 9.5E-8 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Theos_1393 1ceba61d4190a135fe726c7061f73ff5 124 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 9.5E-8 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Theos_1393 1ceba61d4190a135fe726c7061f73ff5 124 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 14-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site Theos_1393 1ceba61d4190a135fe726c7061f73ff5 124 Gene3D G3DSA:1.10.1200.120 1 124 1.8E-36 T 14-10-2018 IPR036019 Gated mechanosensitive channel Theos_1393 1ceba61d4190a135fe726c7061f73ff5 124 SUPERFAMILY SSF81330 10 116 6.67E-29 T 14-10-2018 IPR036019 Gated mechanosensitive channel Theos_1393 1ceba61d4190a135fe726c7061f73ff5 124 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 120 2.3E-33 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Theos_1393 1ceba61d4190a135fe726c7061f73ff5 124 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 120 3.3E-37 T 14-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L Theos_1393 1ceba61d4190a135fe726c7061f73ff5 124 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 122 22.022 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Theos_0290 223b5b089b6d2d303ba44482766b5462 61 Pfam PF00253 Ribosomal protein S14p/S29e 10 60 2.5E-22 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0290 223b5b089b6d2d303ba44482766b5462 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 14-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0290 223b5b089b6d2d303ba44482766b5462 61 Gene3D G3DSA:4.10.830.10 1 61 6.8E-31 T 14-10-2018 Theos_0290 223b5b089b6d2d303ba44482766b5462 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.489 T 14-10-2018 IPR023053 Ribosomal protein S14, type Z Theos_0290 223b5b089b6d2d303ba44482766b5462 61 SUPERFAMILY SSF57716 6 61 8.55E-21 T 14-10-2018 Theos_1599 ea61b85977af3adbff92338301eea834 27 TIGRFAM TIGR04560 ribo_THX: ribosomal small subunit protein bTHX 1 26 2.1E-15 T 14-10-2018 IPR030826 30S ribosomal protein GO:0005840 Theos_1599 ea61b85977af3adbff92338301eea834 27 Pfam PF17070 30S ribosomal protein Thx 1 27 4.4E-18 T 14-10-2018 IPR031414 30S ribosomal protein Thx GO:0005840 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 Gene3D G3DSA:3.10.150.10 131 259 2.3E-25 T 14-10-2018 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 Gene3D G3DSA:3.10.150.10 260 374 4.7E-30 T 14-10-2018 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 362 3.1E-53 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 116 5.4E-14 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 SUPERFAMILY SSF55979 1 115 5.23E-12 T 14-10-2018 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 SUPERFAMILY SSF55979 256 374 3.14E-21 T 14-10-2018 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 SMART SM00480 17 370 6.4E-57 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 257 360 2.7E-18 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 Gene3D G3DSA:3.10.150.10 1 120 4.2E-24 T 14-10-2018 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 PIRSF PIRSF000804 1 374 4.4E-68 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 SUPERFAMILY SSF55979 135 255 3.01E-13 T 14-10-2018 Theos_0002 1d86171a9c0fcc62efbe78060f12550a 374 Pfam PF02767 DNA polymerase III beta subunit, central domain 135 254 7.0E-16 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 Theos_1455 0401be138d7ebfb99fefcbac7de8c76b 418 SUPERFAMILY SSF53474 40 409 8.25E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1455 0401be138d7ebfb99fefcbac7de8c76b 418 Pfam PF12146 Serine aminopeptidase, S33 43 167 9.1E-9 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 Theos_1381 ab4ab78dc8c1cc0315df93b68c5b138f 310 Gene3D G3DSA:3.40.50.720 3 243 4.6E-126 T 14-10-2018 Theos_1381 ab4ab78dc8c1cc0315df93b68c5b138f 310 Gene3D G3DSA:3.90.25.10 175 303 4.6E-126 T 14-10-2018 Theos_1381 ab4ab78dc8c1cc0315df93b68c5b138f 310 SUPERFAMILY SSF51735 1 309 6.22E-91 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1381 ab4ab78dc8c1cc0315df93b68c5b138f 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 3.8E-61 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Theos_0439 001d221dcf4ea4d48704905f8326729f 381 SUPERFAMILY SSF53067 68 181 5.11E-16 T 14-10-2018 Theos_0439 001d221dcf4ea4d48704905f8326729f 381 SUPERFAMILY SSF53067 197 374 1.01E-21 T 14-10-2018 Theos_0439 001d221dcf4ea4d48704905f8326729f 381 Gene3D G3DSA:3.30.420.40 194 340 1.3E-105 T 14-10-2018 Theos_0439 001d221dcf4ea4d48704905f8326729f 381 Gene3D G3DSA:3.30.1490.300 95 155 1.3E-105 T 14-10-2018 Theos_0439 001d221dcf4ea4d48704905f8326729f 381 Pfam PF11104 Type IV pilus assembly protein PilM; 284 376 2.6E-12 T 14-10-2018 IPR005883 Type IV pilus assembly protein PilM Theos_0439 001d221dcf4ea4d48704905f8326729f 381 Pfam PF11104 Type IV pilus assembly protein PilM; 23 254 7.1E-40 T 14-10-2018 IPR005883 Type IV pilus assembly protein PilM Theos_0439 001d221dcf4ea4d48704905f8326729f 381 Gene3D G3DSA:3.30.420.40 22 375 1.3E-105 T 14-10-2018 Theos_0439 001d221dcf4ea4d48704905f8326729f 381 PIRSF PIRSF019169 8 378 1.9E-97 T 14-10-2018 IPR005883 Type IV pilus assembly protein PilM Theos_0439 001d221dcf4ea4d48704905f8326729f 381 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 21 377 2.5E-91 T 14-10-2018 IPR005883 Type IV pilus assembly protein PilM Theos_1355 c94acef127c9fae29c256a0b08247c44 516 Pfam PF05670 Domain of unknown function (DUF814) 403 485 3.8E-25 T 14-10-2018 IPR008532 Domain of unknown function DUF814 Theos_1355 c94acef127c9fae29c256a0b08247c44 516 Gene3D G3DSA:2.30.310.10 1 162 7.4E-21 T 14-10-2018 Theos_1355 c94acef127c9fae29c256a0b08247c44 516 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 3 229 4.1E-31 T 14-10-2018 Theos_1355 c94acef127c9fae29c256a0b08247c44 516 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 243 382 5.0E-21 T 14-10-2018 Theos_1631 b608531dcc94ae3d284e48cd9216eec0 77 Gene3D G3DSA:1.10.10.10 2 62 3.1E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0503 9d0f9175e35a0dee7591cd6c910e64cd 580 SUPERFAMILY SSF90123 12 329 2.88E-71 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Theos_0503 9d0f9175e35a0dee7591cd6c910e64cd 580 Gene3D G3DSA:1.20.1560.10 2 324 1.1E-78 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Theos_0503 9d0f9175e35a0dee7591cd6c910e64cd 580 Gene3D G3DSA:3.40.50.300 333 579 2.4E-80 T 14-10-2018 Theos_0503 9d0f9175e35a0dee7591cd6c910e64cd 580 SUPERFAMILY SSF52540 332 573 5.01E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0503 9d0f9175e35a0dee7591cd6c910e64cd 580 SMART SM00382 363 555 2.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0503 9d0f9175e35a0dee7591cd6c910e64cd 580 Pfam PF00664 ABC transporter transmembrane region 25 291 2.2E-50 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Theos_0503 9d0f9175e35a0dee7591cd6c910e64cd 580 Pfam PF00005 ABC transporter 354 502 5.0E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0503 9d0f9175e35a0dee7591cd6c910e64cd 580 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2507 ba0d2c9fe23416be5d06f2734b4da616 174 Pfam PF04098 Rad52/22 family double-strand break repair protein 8 122 5.1E-8 T 14-10-2018 IPR007232 DNA repair protein Rad52/59/22 GO:0006281|GO:0006310 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938 Theos_0751 398153f2c33e4caf65aa6c76345c66ae 765 Pfam PF01568 Molydopterin dinucleotide binding domain 620 734 7.3E-15 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Theos_0751 398153f2c33e4caf65aa6c76345c66ae 765 Gene3D G3DSA:2.20.25.90 30 96 2.4E-27 T 14-10-2018 Theos_0751 398153f2c33e4caf65aa6c76345c66ae 765 Gene3D G3DSA:2.40.40.20 605 765 2.2E-71 T 14-10-2018 Theos_0751 398153f2c33e4caf65aa6c76345c66ae 765 SUPERFAMILY SSF53706 39 621 8.25E-153 T 14-10-2018 Theos_0751 398153f2c33e4caf65aa6c76345c66ae 765 SUPERFAMILY SSF50692 582 744 2.03E-29 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Theos_0751 398153f2c33e4caf65aa6c76345c66ae 765 Pfam PF00384 Molybdopterin oxidoreductase 94 525 1.1E-58 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0751 398153f2c33e4caf65aa6c76345c66ae 765 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 39 90 9.4E-12 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0751 398153f2c33e4caf65aa6c76345c66ae 765 SMART SM00926 37 91 6.9E-14 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_1548 7cda33e87d91804ab5cccec8a2db380a 400 Pfam PF13439 Glycosyltransferase Family 4 18 179 1.6E-31 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Theos_1548 7cda33e87d91804ab5cccec8a2db380a 400 Gene3D G3DSA:3.40.50.2000 5 187 4.4E-35 T 14-10-2018 Theos_1548 7cda33e87d91804ab5cccec8a2db380a 400 Gene3D G3DSA:3.40.50.2000 188 357 1.7E-40 T 14-10-2018 Theos_1548 7cda33e87d91804ab5cccec8a2db380a 400 Pfam PF00534 Glycosyl transferases group 1 194 351 2.0E-35 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Theos_1548 7cda33e87d91804ab5cccec8a2db380a 400 SUPERFAMILY SSF53756 8 373 2.9E-78 T 14-10-2018 Theos_0871 d0247daf77a001dbcc8845b85e7c6358 456 Pfam PF04293 SpoVR like protein 4 403 2.8E-106 T 14-10-2018 IPR007390 Sporulation stage V, protein R Theos_0029 6e7188991eb4f9449cab2f00c0ff3e8b 261 SUPERFAMILY SSF75217 109 259 1.5E-41 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Theos_0029 6e7188991eb4f9449cab2f00c0ff3e8b 261 Gene3D G3DSA:3.30.1330.30 5 102 8.8E-27 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like Theos_0029 6e7188991eb4f9449cab2f00c0ff3e8b 261 Pfam PF00588 SpoU rRNA Methylase family 115 253 2.5E-31 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Theos_0029 6e7188991eb4f9449cab2f00c0ff3e8b 261 SUPERFAMILY SSF55315 6 102 7.3E-19 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like Theos_0029 6e7188991eb4f9449cab2f00c0ff3e8b 261 Gene3D G3DSA:3.40.1280.10 109 261 2.8E-54 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Theos_1623 382c11a6cc6e0f1b673925a81578fe31 255 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 40 253 7.2E-67 T 14-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 Theos_1623 382c11a6cc6e0f1b673925a81578fe31 255 Gene3D G3DSA:1.10.760.10 131 255 6.0E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1623 382c11a6cc6e0f1b673925a81578fe31 255 Gene3D G3DSA:1.10.760.10 42 130 3.0E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1623 382c11a6cc6e0f1b673925a81578fe31 255 PIRSF PIRSF038455 10 255 1.9E-69 T 14-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 Theos_1623 382c11a6cc6e0f1b673925a81578fe31 255 SUPERFAMILY SSF46626 40 136 2.01E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1623 382c11a6cc6e0f1b673925a81578fe31 255 SUPERFAMILY SSF46626 141 248 2.75E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_2311 64b9aac6ee88f5c884299f892f78c5c2 230 Pfam PF02654 Cobalamin-5-phosphate synthase 7 220 1.1E-43 T 14-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 Theos_2311 64b9aac6ee88f5c884299f892f78c5c2 230 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 230 36.892 T 14-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 Theos_1108 9134d1479bfc97adfb41e1eef8dab417 180 SUPERFAMILY SSF56235 2 177 9.77E-52 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_1108 9134d1479bfc97adfb41e1eef8dab417 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 6 176 1.7E-70 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Theos_1108 9134d1479bfc97adfb41e1eef8dab417 180 Gene3D G3DSA:3.60.20.10 1 177 2.3E-55 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_1108 9134d1479bfc97adfb41e1eef8dab417 180 Pfam PF00227 Proteasome subunit 4 176 5.7E-20 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Theos_2016 fe0aa16722041bb84e68f49ea399b37b 300 SUPERFAMILY SSF55781 69 288 2.16E-18 T 14-10-2018 Theos_2016 fe0aa16722041bb84e68f49ea399b37b 300 Gene3D G3DSA:1.10.10.10 1 79 4.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2016 fe0aa16722041bb84e68f49ea399b37b 300 SUPERFAMILY SSF46785 2 78 3.91E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2016 fe0aa16722041bb84e68f49ea399b37b 300 PIRSF PIRSF005485 1 181 2.6E-31 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Theos_2016 fe0aa16722041bb84e68f49ea399b37b 300 PIRSF PIRSF005485 184 298 0.0055 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Theos_2016 fe0aa16722041bb84e68f49ea399b37b 300 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 291 14.424 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Theos_2016 fe0aa16722041bb84e68f49ea399b37b 300 Pfam PF01726 LexA DNA binding domain 2 53 2.4E-5 T 14-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 Theos_2016 fe0aa16722041bb84e68f49ea399b37b 300 Pfam PF01628 HrcA protein C terminal domain 104 282 1.1E-11 T 14-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 Theos_1384 360d3896d689c789211012f9e0f6a505 394 Gene3D G3DSA:3.40.50.2300 152 289 7.8E-74 T 14-10-2018 Theos_1384 360d3896d689c789211012f9e0f6a505 394 Gene3D G3DSA:3.40.50.2300 39 354 7.8E-74 T 14-10-2018 Theos_1384 360d3896d689c789211012f9e0f6a505 394 SUPERFAMILY SSF53822 30 389 1.72E-62 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_1384 360d3896d689c789211012f9e0f6a505 394 Pfam PF13458 Periplasmic binding protein 30 380 1.4E-62 T 14-10-2018 IPR028081 Leucine-binding protein domain Theos_1118 397399a58d4ba47332ea044825434361 144 Gene3D G3DSA:2.40.330.20 1 134 5.4E-41 T 14-10-2018 IPR038619 MraZ superfamily Theos_1118 397399a58d4ba47332ea044825434361 144 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 128 3.0E-33 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Theos_1118 397399a58d4ba47332ea044825434361 144 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 139 2.0E-69 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Theos_1118 397399a58d4ba47332ea044825434361 144 Pfam PF02381 MraZ protein, putative antitoxin-like 72 130 4.1E-12 T 14-10-2018 IPR020603 MraZ domain Theos_1118 397399a58d4ba47332ea044825434361 144 Pfam PF02381 MraZ protein, putative antitoxin-like 4 70 1.9E-17 T 14-10-2018 IPR020603 MraZ domain Theos_1118 397399a58d4ba47332ea044825434361 144 SUPERFAMILY SSF89447 1 132 2.84E-42 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Theos_1118 397399a58d4ba47332ea044825434361 144 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 144 45.097 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Theos_0870 9c71fbd6690888e1cbe59563ec73e772 267 SUPERFAMILY SSF52833 136 261 1.25E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0870 9c71fbd6690888e1cbe59563ec73e772 267 Gene3D G3DSA:3.40.30.10 121 262 1.1E-36 T 14-10-2018 Theos_0870 9c71fbd6690888e1cbe59563ec73e772 267 Pfam PF08534 Redoxin 134 252 4.5E-19 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 Theos_0870 9c71fbd6690888e1cbe59563ec73e772 267 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 100 2.0E-8 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Theos_1870 1f43c6e25f4d86a18c0123c46eb74fcf 413 Gene3D G3DSA:1.20.1250.20 5 396 4.1E-31 T 14-10-2018 Theos_1870 1f43c6e25f4d86a18c0123c46eb74fcf 413 SUPERFAMILY SSF103473 7 402 6.93E-40 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1870 1f43c6e25f4d86a18c0123c46eb74fcf 413 Pfam PF07690 Major Facilitator Superfamily 10 348 3.3E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 PIRSF PIRSF004749 1 189 3.4E-51 T 14-10-2018 IPR023635 Peptide deformylase Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 Hamap MF_00163 Peptide deformylase [def]. 4 176 30.639 T 14-10-2018 IPR023635 Peptide deformylase Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 Gene3D G3DSA:3.90.45.10 4 194 4.1E-78 T 14-10-2018 IPR036821 Peptide deformylase superfamily Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 10 172 1.6E-39 T 14-10-2018 IPR023635 Peptide deformylase Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 PRINTS PR01576 Peptide deformylase signature 115 133 8.2E-38 T 14-10-2018 IPR023635 Peptide deformylase Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 PRINTS PR01576 Peptide deformylase signature 134 163 8.2E-38 T 14-10-2018 IPR023635 Peptide deformylase Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 PRINTS PR01576 Peptide deformylase signature 102 113 8.2E-38 T 14-10-2018 IPR023635 Peptide deformylase Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 PRINTS PR01576 Peptide deformylase signature 34 63 8.2E-38 T 14-10-2018 IPR023635 Peptide deformylase Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 SUPERFAMILY SSF56420 4 173 3.79E-57 T 14-10-2018 IPR036821 Peptide deformylase superfamily Theos_0214 1cdafff7b08cf510d390df0f556fdbd3 194 Pfam PF01327 Polypeptide deformylase 6 166 3.3E-51 T 14-10-2018 IPR023635 Peptide deformylase Theos_1804 837a73139341887f7c899c4fdadf154d 345 SUPERFAMILY SSF56176 2 170 1.02E-32 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Theos_1804 837a73139341887f7c899c4fdadf154d 345 Pfam PF01565 FAD binding domain 2 131 8.7E-25 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Theos_1804 837a73139341887f7c899c4fdadf154d 345 SUPERFAMILY SSF55103 173 342 2.83E-5 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Theos_1804 837a73139341887f7c899c4fdadf154d 345 Gene3D G3DSA:3.30.465.40 1 188 4.1E-33 T 14-10-2018 Theos_1867 378248aca1450e200549afccf20beb8e 434 ProSitePatterns PS00571 Amidases signature. 145 176 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 Theos_1867 378248aca1450e200549afccf20beb8e 434 Gene3D G3DSA:3.90.1300.10 1 434 4.6E-177 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Theos_1867 378248aca1450e200549afccf20beb8e 434 SUPERFAMILY SSF75304 2 433 1.96E-122 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Theos_1867 378248aca1450e200549afccf20beb8e 434 Pfam PF01425 Amidase 19 423 2.6E-94 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Theos_0538 a6a3f1bbbe1ec99fc73696426367ccf0 288 Pfam PF01266 FAD dependent oxidoreductase 4 285 1.2E-7 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Theos_0538 a6a3f1bbbe1ec99fc73696426367ccf0 288 SUPERFAMILY SSF51971 4 287 2.35E-13 T 14-10-2018 Theos_1974 4e2ee05a442b48b82be682e31e3bab4c 209 SUPERFAMILY SSF53254 2 198 1.7E-61 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_1974 4e2ee05a442b48b82be682e31e3bab4c 209 SMART SM00855 3 155 7.9E-27 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Theos_1974 4e2ee05a442b48b82be682e31e3bab4c 209 PIRSF PIRSF000709 1 180 1.1E-19 T 14-10-2018 Theos_1974 4e2ee05a442b48b82be682e31e3bab4c 209 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 186 1.1E-58 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Theos_1974 4e2ee05a442b48b82be682e31e3bab4c 209 Gene3D G3DSA:3.40.50.1240 1 202 1.7E-59 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_1974 4e2ee05a442b48b82be682e31e3bab4c 209 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 Theos_0580 1680e4d9ea47c140ad4bc8f0f2c5bda0 372 Gene3D G3DSA:3.20.20.70 12 330 2.2E-50 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0580 1680e4d9ea47c140ad4bc8f0f2c5bda0 372 SUPERFAMILY SSF102114 19 357 4.84E-55 T 14-10-2018 Theos_0580 1680e4d9ea47c140ad4bc8f0f2c5bda0 372 Pfam PF04055 Radical SAM superfamily 65 236 3.2E-12 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_0580 1680e4d9ea47c140ad4bc8f0f2c5bda0 372 SMART SM00729 59 268 2.5E-4 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_0580 1680e4d9ea47c140ad4bc8f0f2c5bda0 372 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 10 367 51.699 T 14-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 Theos_0580 1680e4d9ea47c140ad4bc8f0f2c5bda0 372 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 12 364 5.5E-165 T 14-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 Theos_0580 1680e4d9ea47c140ad4bc8f0f2c5bda0 372 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 56 363 5.7E-105 T 14-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 Theos_0580 1680e4d9ea47c140ad4bc8f0f2c5bda0 372 PIRSF PIRSF004762 1 371 8.9E-110 T 14-10-2018 Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 SUPERFAMILY SSF50129 7 99 2.24E-35 T 14-10-2018 IPR011032 GroES-like superfamily Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 PRINTS PR00297 10kDa chaperonin signature 65 77 6.5E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 PRINTS PR00297 10kDa chaperonin signature 30 51 6.5E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 PRINTS PR00297 10kDa chaperonin signature 8 23 6.5E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 PRINTS PR00297 10kDa chaperonin signature 86 99 6.5E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 ProSitePatterns PS00681 Chaperonins cpn10 signature. 8 32 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 Pfam PF00166 Chaperonin 10 Kd subunit 8 98 1.2E-36 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 Gene3D G3DSA:2.30.33.40 7 100 6.6E-40 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 SMART SM00883 7 99 2.7E-54 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Theos_0028 1d19c254cb9a53bf9b9f7f1175125a77 100 Hamap MF_00580 10 kDa chaperonin [groS]. 7 100 27.868 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Theos_0374 3cde25575478c65d40c6f89a68e94392 475 SMART SM00387 359 469 1.8E-44 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0374 3cde25575478c65d40c6f89a68e94392 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 2.1E-21 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0374 3cde25575478c65d40c6f89a68e94392 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 2.1E-21 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0374 3cde25575478c65d40c6f89a68e94392 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 2.1E-21 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0374 3cde25575478c65d40c6f89a68e94392 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 2.1E-21 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0374 3cde25575478c65d40c6f89a68e94392 475 Gene3D G3DSA:1.10.287.130 199 318 5.4E-24 T 14-10-2018 Theos_0374 3cde25575478c65d40c6f89a68e94392 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 317 8.9E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0374 3cde25575478c65d40c6f89a68e94392 475 Gene3D G3DSA:3.30.565.10 326 469 7.8E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0374 3cde25575478c65d40c6f89a68e94392 475 SUPERFAMILY SSF47384 236 317 1.22E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_0374 3cde25575478c65d40c6f89a68e94392 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 467 2.1E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0374 3cde25575478c65d40c6f89a68e94392 475 SUPERFAMILY SSF55874 309 467 1.15E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0374 3cde25575478c65d40c6f89a68e94392 475 SMART SM00304 194 252 2.2E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Theos_0374 3cde25575478c65d40c6f89a68e94392 475 SMART SM00388 253 319 3.2E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_1982 0608e71bcad4db2166e3d7ab7d4f2378 268 SUPERFAMILY SSF52540 27 169 7.03E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1982 0608e71bcad4db2166e3d7ab7d4f2378 268 Gene3D G3DSA:3.40.50.300 22 159 1.4E-27 T 14-10-2018 Theos_1982 0608e71bcad4db2166e3d7ab7d4f2378 268 Pfam PF13177 DNA polymerase III, delta subunit 61 159 1.7E-19 T 14-10-2018 Theos_0805 da2b369903c68754a9a6cf905f024e67 373 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 234 1.5E-44 T 14-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 Theos_0805 da2b369903c68754a9a6cf905f024e67 373 SUPERFAMILY SSF56300 1 307 4.68E-50 T 14-10-2018 Theos_0805 da2b369903c68754a9a6cf905f024e67 373 Pfam PF00149 Calcineurin-like phosphoesterase 1 122 5.4E-13 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Theos_0805 da2b369903c68754a9a6cf905f024e67 373 Gene3D G3DSA:3.60.21.10 1 260 8.9E-61 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 48 1.2E-14 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 Gene3D G3DSA:3.40.50.300 69 240 1.6E-75 T 14-10-2018 Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 Pfam PF11987 Translation-initiation factor 2 360 462 1.3E-31 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 73 230 1.1E-33 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 3 569 2.6E-204 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 ProSitePatterns PS01176 Initiation factor 2 signature. 524 546 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 571 14.585 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 Gene3D G3DSA:1.10.10.2480 1 68 2.0E-27 T 14-10-2018 Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 SUPERFAMILY SSF52156 356 480 8.5E-33 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 Gene3D G3DSA:3.40.50.10050 367 474 1.1E-35 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 Gene3D G3DSA:2.40.30.10 475 571 1.8E-35 T 14-10-2018 Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 SUPERFAMILY SSF52540 56 242 8.5E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 SUPERFAMILY SSF50447 244 326 9.54E-19 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 Pfam PF00009 Elongation factor Tu GTP binding domain 76 232 3.8E-36 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 SUPERFAMILY SSF50447 474 570 1.85E-31 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Theos_1170 1763de0caff12e9c1a27c24ebd813e6f 571 Gene3D G3DSA:2.40.30.10 241 363 4.9E-42 T 14-10-2018 Theos_1199 4945c04069270f327c210a72ba5b97ef 241 PIRSF PIRSF004808 1 239 1.5E-75 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Theos_1199 4945c04069270f327c210a72ba5b97ef 241 Gene3D G3DSA:3.40.1280.10 1 164 2.9E-55 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Theos_1199 4945c04069270f327c210a72ba5b97ef 241 SUPERFAMILY SSF75217 3 163 2.42E-31 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Theos_1199 4945c04069270f327c210a72ba5b97ef 241 Pfam PF00588 SpoU rRNA Methylase family 4 156 2.9E-38 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Theos_1199 4945c04069270f327c210a72ba5b97ef 241 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 3 229 1.5E-65 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Theos_1199 4945c04069270f327c210a72ba5b97ef 241 Gene3D G3DSA:1.10.8.590 165 239 1.4E-14 T 14-10-2018 Theos_1050 15287d7ac112219510ec1a2964d654da 402 Gene3D G3DSA:3.50.50.100 2 381 1.4E-114 T 14-10-2018 Theos_1050 15287d7ac112219510ec1a2964d654da 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.9E-16 T 14-10-2018 Theos_1050 15287d7ac112219510ec1a2964d654da 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 2.9E-16 T 14-10-2018 Theos_1050 15287d7ac112219510ec1a2964d654da 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 2.9E-16 T 14-10-2018 Theos_1050 15287d7ac112219510ec1a2964d654da 402 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 3.0E-13 T 14-10-2018 Theos_1050 15287d7ac112219510ec1a2964d654da 402 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 3.0E-13 T 14-10-2018 Theos_1050 15287d7ac112219510ec1a2964d654da 402 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 281 288 3.0E-13 T 14-10-2018 Theos_1050 15287d7ac112219510ec1a2964d654da 402 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.0E-13 T 14-10-2018 Theos_1050 15287d7ac112219510ec1a2964d654da 402 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 303 3.2E-60 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Theos_1050 15287d7ac112219510ec1a2964d654da 402 SUPERFAMILY SSF51905 4 314 4.18E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2361 e3c94531a9aaf4561d848f23afe6c6bc 343 Gene3D G3DSA:1.10.3470.10 8 338 4.4E-95 T 14-10-2018 IPR037294 ABC transporter, BtuC-like Theos_2361 e3c94531a9aaf4561d848f23afe6c6bc 343 SUPERFAMILY SSF81345 6 333 3.66E-78 T 14-10-2018 IPR037294 ABC transporter, BtuC-like Theos_2361 e3c94531a9aaf4561d848f23afe6c6bc 343 Pfam PF01032 FecCD transport family 22 333 1.3E-83 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Theos_1800 df879c801a38381f21830709cb69d564 253 SUPERFAMILY SSF46785 12 83 4.06E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1800 df879c801a38381f21830709cb69d564 253 Pfam PF01614 Bacterial transcriptional regulator 130 243 2.8E-33 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal Theos_1800 df879c801a38381f21830709cb69d564 253 Gene3D G3DSA:3.30.450.40 79 251 6.1E-58 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1800 df879c801a38381f21830709cb69d564 253 SUPERFAMILY SSF55781 67 249 3.07E-52 T 14-10-2018 Theos_1800 df879c801a38381f21830709cb69d564 253 Gene3D G3DSA:1.10.10.10 5 78 9.4E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1800 df879c801a38381f21830709cb69d564 253 SMART SM00346 12 98 6.5E-24 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Theos_1800 df879c801a38381f21830709cb69d564 253 Pfam PF09339 IclR helix-turn-helix domain 14 63 2.1E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Theos_0165 059a89076f12c1eb0f2dbfcd42f463df 292 Pfam PF00005 ABC transporter 19 160 1.5E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0165 059a89076f12c1eb0f2dbfcd42f463df 292 SUPERFAMILY SSF52540 4 212 7.75E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0165 059a89076f12c1eb0f2dbfcd42f463df 292 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0165 059a89076f12c1eb0f2dbfcd42f463df 292 Gene3D G3DSA:3.40.50.300 1 223 4.7E-64 T 14-10-2018 Theos_0165 059a89076f12c1eb0f2dbfcd42f463df 292 SMART SM00382 28 207 1.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2189 f1cf69d0c8b55b6dee22a5a55ff8ace4 100 Gene3D G3DSA:3.40.1620.10 4 43 2.8E-5 T 14-10-2018 Theos_2189 f1cf69d0c8b55b6dee22a5a55ff8ace4 100 SUPERFAMILY SSF143120 6 53 2.88E-10 T 14-10-2018 IPR036165 YefM-like superfamily Theos_2189 f1cf69d0c8b55b6dee22a5a55ff8ace4 100 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 8 58 3.3E-14 T 14-10-2018 Theos_2189 f1cf69d0c8b55b6dee22a5a55ff8ace4 100 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 63 1.6E-13 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Theos_1829 2641b3f1ec236a8ee6b536fb8980a90a 65 SUPERFAMILY SSF54285 9 65 2.78E-11 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Theos_1829 2641b3f1ec236a8ee6b536fb8980a90a 65 Pfam PF02597 ThiS family 10 65 2.0E-5 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Theos_1829 2641b3f1ec236a8ee6b536fb8980a90a 65 Gene3D G3DSA:3.10.20.30 1 65 2.4E-15 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Theos_1761 5631f990f9a28255d5cd786199561603 257 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 77 99 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Theos_1761 5631f990f9a28255d5cd786199561603 257 Gene3D G3DSA:1.20.120.1760 6 180 5.2E-23 T 14-10-2018 Theos_1761 5631f990f9a28255d5cd786199561603 257 Pfam PF01066 CDP-alcohol phosphatidyltransferase 39 97 2.8E-7 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Theos_0620 e611b14d102c444c52a6a24d1b238af4 161 Gene3D G3DSA:3.40.1520.10 1 161 5.1E-75 T 14-10-2018 IPR036902 Ta1353-like superfamily Theos_0620 e611b14d102c444c52a6a24d1b238af4 161 SUPERFAMILY SSF103165 1 161 9.68E-70 T 14-10-2018 IPR036902 Ta1353-like superfamily Theos_0620 e611b14d102c444c52a6a24d1b238af4 161 Pfam PF04008 Adenosine specific kinase 6 160 8.5E-71 T 14-10-2018 IPR007153 Adenosine specific kinase Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 SUPERFAMILY SSF158791 8 130 2.35E-25 T 14-10-2018 Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 Gene3D G3DSA:1.10.357.20 270 447 4.3E-62 T 14-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 Pfam PF00571 CBS domain 197 252 1.6E-13 T 14-10-2018 IPR000644 CBS domain Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 Pfam PF00571 CBS domain 134 191 9.6E-12 T 14-10-2018 IPR000644 CBS domain Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 Pfam PF03448 MgtE intracellular N domain 28 131 2.1E-23 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 Gene3D G3DSA:1.25.60.10 2 128 1.6E-38 T 14-10-2018 IPR038076 MgtE, N-terminal domain superfamily Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 Pfam PF01769 Divalent cation transporter 319 439 9.5E-29 T 14-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 TIGRFAM TIGR00400 mgtE: magnesium transporter 11 447 3.3E-125 T 14-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 SMART SM00924 27 133 1.2E-24 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 SUPERFAMILY SSF161093 277 446 7.45E-49 T 14-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 Gene3D G3DSA:3.10.580.10 129 251 4.6E-53 T 14-10-2018 Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 SMART SM00116 204 252 3.2E-10 T 14-10-2018 IPR000644 CBS domain Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 SMART SM00116 140 193 4.1E-4 T 14-10-2018 IPR000644 CBS domain Theos_0898 3ee6c4176cb31c221232e6e699dd2286 448 SUPERFAMILY SSF54631 133 265 6.06E-41 T 14-10-2018 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 PRINTS PR00688 Xylose isomerase signature 104 123 2.8E-54 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 PRINTS PR00688 Xylose isomerase signature 155 174 2.8E-54 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 PRINTS PR00688 Xylose isomerase signature 280 291 2.8E-54 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 PRINTS PR00688 Xylose isomerase signature 177 201 2.8E-54 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 PRINTS PR00688 Xylose isomerase signature 44 66 2.8E-54 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 PRINTS PR00688 Xylose isomerase signature 219 246 2.8E-54 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 PRINTS PR00688 Xylose isomerase signature 128 149 2.8E-54 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 PRINTS PR00688 Xylose isomerase signature 81 101 2.8E-54 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 2 383 4.7E-206 T 14-10-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 SUPERFAMILY SSF51658 2 386 1.57E-113 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 Hamap MF_00455 Xylose isomerase [xylA]. 1 382 35.58 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 Gene3D G3DSA:3.20.20.150 1 387 1.8E-138 T 14-10-2018 Theos_1293 f5f3a23762789b4405763a56221b9b9f 387 Pfam PF01261 Xylose isomerase-like TIM barrel 41 256 4.5E-22 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Theos_0115 eb9b342aead99478c82b38b142c59a20 438 Gene3D G3DSA:3.20.20.60 11 416 7.7E-175 T 14-10-2018 Theos_0115 eb9b342aead99478c82b38b142c59a20 438 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 16 254 2.8E-102 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Theos_0115 eb9b342aead99478c82b38b142c59a20 438 PIRSF PIRSF001362 7 436 3.1E-238 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Theos_0115 eb9b342aead99478c82b38b142c59a20 438 Pfam PF00463 Isocitrate lyase family 257 433 2.6E-50 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Theos_0115 eb9b342aead99478c82b38b142c59a20 438 Pfam PF00463 Isocitrate lyase family 16 254 5.8E-62 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Theos_0115 eb9b342aead99478c82b38b142c59a20 438 SUPERFAMILY SSF51621 12 433 7.63E-155 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Theos_0115 eb9b342aead99478c82b38b142c59a20 438 ProSitePatterns PS00161 Isocitrate lyase signature. 193 198 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 Theos_1647 f0a3659592c013d001230641408523d2 621 Gene3D G3DSA:1.10.599.10 240 612 5.6E-109 T 14-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 Theos_1647 f0a3659592c013d001230641408523d2 621 SUPERFAMILY SSF48310 219 620 3.14E-99 T 14-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_1647 f0a3659592c013d001230641408523d2 621 Gene3D G3DSA:1.10.569.10 241 430 5.6E-109 T 14-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 Theos_1647 f0a3659592c013d001230641408523d2 621 SUPERFAMILY SSF56228 4 208 1.14E-64 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Theos_1647 f0a3659592c013d001230641408523d2 621 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 225 611 6.7E-104 T 14-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_1647 f0a3659592c013d001230641408523d2 621 Gene3D G3DSA:3.60.9.10 3 209 1.4E-70 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Theos_1647 f0a3659592c013d001230641408523d2 621 SMART SM00790 5 207 2.3E-106 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_1647 f0a3659592c013d001230641408523d2 621 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 204 8.5E-66 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_0960 45949b4866ed352c66b7af78aa38b2d1 112 Gene3D G3DSA:3.30.460.10 7 105 5.2E-13 T 14-10-2018 Theos_0960 45949b4866ed352c66b7af78aa38b2d1 112 Pfam PF01909 Nucleotidyltransferase domain 27 68 1.3E-10 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Theos_0960 45949b4866ed352c66b7af78aa38b2d1 112 SUPERFAMILY SSF81301 16 95 9.12E-15 T 14-10-2018 Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 Pfam PF13360 PQQ-like domain 383 457 7.3E-9 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 SMART SM00564 505 536 0.42 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 SMART SM00564 464 496 3.1E-4 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 SMART SM00564 388 417 92.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 SMART SM00564 543 574 18.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 SMART SM00564 425 457 0.017 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 SUPERFAMILY SSF56112 5 262 2.56E-72 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 Gene3D G3DSA:1.10.510.10 101 272 7.3E-48 T 14-10-2018 Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 Gene3D G3DSA:2.130.10.10 368 604 5.6E-46 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 Pfam PF13570 PQQ-like domain 490 528 9.1E-9 T 14-10-2018 IPR025666 Pyrrolo-quinoline quinone-like domain Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 Pfam PF13570 PQQ-like domain 529 566 3.0E-5 T 14-10-2018 IPR025666 Pyrrolo-quinoline quinone-like domain Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 SUPERFAMILY SSF50998 275 602 7.53E-38 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 Gene3D G3DSA:3.30.200.20 3 87 5.6E-26 T 14-10-2018 Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 Pfam PF00069 Protein kinase domain 10 256 8.0E-46 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Theos_0227 0d41271ed7dc6dd00e3cac8384178e93 604 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 127 139 - T 14-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 Theos_2321 6e83380fe071ea70f73d078f604c1907 287 Gene3D G3DSA:3.30.950.10 133 260 1.7E-51 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Theos_2321 6e83380fe071ea70f73d078f604c1907 287 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 229 2.8E-37 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Theos_2321 6e83380fe071ea70f73d078f604c1907 287 Gene3D G3DSA:3.40.1010.10 1 132 7.9E-36 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Theos_2321 6e83380fe071ea70f73d078f604c1907 287 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 4 262 5.6E-89 T 14-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 Theos_2321 6e83380fe071ea70f73d078f604c1907 287 SUPERFAMILY SSF53790 1 262 6.28E-55 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Theos_1661 28d7226d8ea150721b3d9e28b4a6face 121 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 2 104 4.2E-17 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1661 28d7226d8ea150721b3d9e28b4a6face 121 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2 101 1.2E-17 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1661 28d7226d8ea150721b3d9e28b4a6face 121 Gene3D G3DSA:1.20.1300.10 2 110 8.5E-15 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1661 28d7226d8ea150721b3d9e28b4a6face 121 PIRSF PIRSF000178 6 111 4.5E-8 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1661 28d7226d8ea150721b3d9e28b4a6face 121 SUPERFAMILY SSF81343 2 108 5.4E-21 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1963 bf7d8bcdacbe8ec87e0525714d074e54 201 Gene3D G3DSA:3.90.420.10 13 194 3.9E-50 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Theos_1963 bf7d8bcdacbe8ec87e0525714d074e54 201 SUPERFAMILY SSF56524 4 185 4.19E-62 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Theos_1963 bf7d8bcdacbe8ec87e0525714d074e54 201 Pfam PF00174 Oxidoreductase molybdopterin binding domain 24 167 6.1E-36 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 Theos_2433 e9a94ebc0cd30f6f0f375cb469e59a68 358 SUPERFAMILY SSF51556 43 329 3.09E-83 T 14-10-2018 IPR032466 Metal-dependent hydrolase Theos_2433 e9a94ebc0cd30f6f0f375cb469e59a68 358 PIRSF PIRSF038994 16 357 1.8E-95 T 14-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 Theos_2433 e9a94ebc0cd30f6f0f375cb469e59a68 358 Gene3D G3DSA:2.30.40.10 33 343 3.0E-99 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Theos_2433 e9a94ebc0cd30f6f0f375cb469e59a68 358 Pfam PF01979 Amidohydrolase family 40 343 8.5E-17 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Theos_2433 e9a94ebc0cd30f6f0f375cb469e59a68 358 Gene3D G3DSA:3.20.20.140 44 326 3.0E-99 T 14-10-2018 Theos_0785 7295dc0db9a6884d29438b488469ce17 396 Gene3D G3DSA:3.40.47.10 5 279 1.8E-136 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0785 7295dc0db9a6884d29438b488469ce17 396 ProSitePatterns PS00737 Thiolases signature 2. 342 358 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Theos_0785 7295dc0db9a6884d29438b488469ce17 396 SUPERFAMILY SSF53901 274 395 2.76E-34 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0785 7295dc0db9a6884d29438b488469ce17 396 SUPERFAMILY SSF53901 3 273 1.63E-81 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_0785 7295dc0db9a6884d29438b488469ce17 396 PIRSF PIRSF000429 1 396 3.6E-124 T 14-10-2018 IPR002155 Thiolase GO:0016747 Theos_0785 7295dc0db9a6884d29438b488469ce17 396 Pfam PF02803 Thiolase, C-terminal domain 274 394 3.2E-34 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Theos_0785 7295dc0db9a6884d29438b488469ce17 396 Pfam PF00108 Thiolase, N-terminal domain 5 266 3.2E-82 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Theos_0785 7295dc0db9a6884d29438b488469ce17 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 394 5.2E-128 T 14-10-2018 IPR002155 Thiolase GO:0016747 Theos_0785 7295dc0db9a6884d29438b488469ce17 396 Gene3D G3DSA:3.40.47.10 126 391 1.8E-136 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 Gene3D G3DSA:3.40.1830.10 1 177 2.1E-60 T 14-10-2018 IPR035097 Peptidase M29, N-terminal Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 387 406 1.2E-85 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 1.2E-85 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 1.2E-85 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 1.2E-85 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 1.2E-85 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 1.2E-85 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 1.2E-85 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 361 383 1.2E-85 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 SUPERFAMILY SSF144052 4 407 7.72E-133 T 14-10-2018 Theos_1520 0ee58c58ee4beef572cb49daea6a35a8 408 Pfam PF02073 Thermophilic metalloprotease (M29) 5 406 5.7E-151 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_0900 a38caa05e62e973a9afb59cddc4730c8 84 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 77 25.034 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0900 a38caa05e62e973a9afb59cddc4730c8 84 Pfam PF00886 Ribosomal protein S16 8 67 1.3E-25 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0900 a38caa05e62e973a9afb59cddc4730c8 84 Gene3D G3DSA:3.30.1320.10 1 84 1.0E-36 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0900 a38caa05e62e973a9afb59cddc4730c8 84 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 80 3.0E-34 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0900 a38caa05e62e973a9afb59cddc4730c8 84 SUPERFAMILY SSF54565 1 82 6.28E-33 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0712 8ddca97510f6fd1c859dffcd9afc542e 181 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 114 132 - T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0712 8ddca97510f6fd1c859dffcd9afc542e 181 Gene3D G3DSA:3.40.30.10 75 181 5.8E-36 T 14-10-2018 Theos_0712 8ddca97510f6fd1c859dffcd9afc542e 181 Gene3D G3DSA:1.10.10.1590 1 74 2.9E-29 T 14-10-2018 Theos_0712 8ddca97510f6fd1c859dffcd9afc542e 181 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 12 157 1.6E-54 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0712 8ddca97510f6fd1c859dffcd9afc542e 181 PIRSF PIRSF000216 1 180 2.9E-66 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0712 8ddca97510f6fd1c859dffcd9afc542e 181 SUPERFAMILY SSF52833 7 170 4.36E-52 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0712 8ddca97510f6fd1c859dffcd9afc542e 181 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 12 157 1.1E-49 T 14-10-2018 Theos_2336 0078ea71da39c3c4533363fdd3ef1704 836 SMART SM00028 370 403 3.3 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_2336 0078ea71da39c3c4533363fdd3ef1704 836 SMART SM00028 501 534 5.7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_2336 0078ea71da39c3c4533363fdd3ef1704 836 SUPERFAMILY SSF48452 431 531 3.03E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2336 0078ea71da39c3c4533363fdd3ef1704 836 SUPERFAMILY SSF48452 342 531 2.5E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2336 0078ea71da39c3c4533363fdd3ef1704 836 SUPERFAMILY SSF52540 8 184 4.3E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2336 0078ea71da39c3c4533363fdd3ef1704 836 Pfam PF13181 Tetratricopeptide repeat 343 366 0.024 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_2336 0078ea71da39c3c4533363fdd3ef1704 836 Pfam PF13181 Tetratricopeptide repeat 507 531 0.14 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0555 bdef984791c368e95d06eb5e0f587e44 181 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 38.133 T 14-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 Theos_0555 bdef984791c368e95d06eb5e0f587e44 181 Gene3D G3DSA:3.40.50.2020 1 181 3.5E-63 T 14-10-2018 Theos_0555 bdef984791c368e95d06eb5e0f587e44 181 Pfam PF00156 Phosphoribosyl transferase domain 8 148 3.0E-22 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Theos_0555 bdef984791c368e95d06eb5e0f587e44 181 SUPERFAMILY SSF53271 6 172 5.24E-45 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_0068 9e1ae0b8409841e3c01a0f81dd5c48b0 338 Pfam PF01757 Acyltransferase family 5 323 1.1E-29 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Theos_0121 a250e563e987cdd1aca88802dbc3466c 333 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 14 333 29.07 T 14-10-2018 IPR003770 Endolytic murein transglycosylase Theos_0121 a250e563e987cdd1aca88802dbc3466c 333 Pfam PF02618 YceG-like family 40 327 3.1E-69 T 14-10-2018 IPR003770 Endolytic murein transglycosylase Theos_0121 a250e563e987cdd1aca88802dbc3466c 333 Gene3D G3DSA:1.10.8.1150 35 102 5.0E-9 T 14-10-2018 Theos_0121 a250e563e987cdd1aca88802dbc3466c 333 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 36 325 6.8E-51 T 14-10-2018 IPR003770 Endolytic murein transglycosylase Theos_0405 b96ad32f3aa5f1482d06f67261b7b699 257 SUPERFAMILY SSF53649 1 232 1.99E-11 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Theos_0405 b96ad32f3aa5f1482d06f67261b7b699 257 Pfam PF01676 Metalloenzyme superfamily 193 227 1.3E-5 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 Theos_0300 39c5d49b9e74c38bd4c072bbc7079cac 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 6 72 1.4E-33 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Theos_0300 39c5d49b9e74c38bd4c072bbc7079cac 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 24.349 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Theos_0300 39c5d49b9e74c38bd4c072bbc7079cac 72 Pfam PF01176 Translation initiation factor 1A / IF-1 10 71 7.4E-27 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 Theos_0300 39c5d49b9e74c38bd4c072bbc7079cac 72 Gene3D G3DSA:2.40.50.140 2 72 6.6E-37 T 14-10-2018 Theos_0300 39c5d49b9e74c38bd4c072bbc7079cac 72 SUPERFAMILY SSF50249 4 71 3.43E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 Gene3D G3DSA:1.10.275.10 31 219 3.9E-85 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 PRINTS PR00145 Argininosuccinate lyase family signature 183 199 2.5E-24 T 14-10-2018 Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 PRINTS PR00145 Argininosuccinate lyase family signature 221 245 2.5E-24 T 14-10-2018 Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 PRINTS PR00145 Argininosuccinate lyase family signature 91 113 2.5E-24 T 14-10-2018 Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 PRINTS PR00145 Argininosuccinate lyase family signature 132 152 2.5E-24 T 14-10-2018 Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 PRINTS PR00145 Argininosuccinate lyase family signature 263 279 2.5E-24 T 14-10-2018 Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 Pfam PF00206 Lyase 86 288 1.0E-35 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 Gene3D G3DSA:1.20.200.10 109 348 3.9E-85 T 14-10-2018 Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 ProSitePatterns PS00163 Fumarate lyases signature. 263 272 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 PRINTS PR00149 Fumarate lyase superfamily signature 92 110 9.9E-17 T 14-10-2018 IPR000362 Fumarate lyase family Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 9.9E-17 T 14-10-2018 IPR000362 Fumarate lyase family Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 PRINTS PR00149 Fumarate lyase superfamily signature 221 248 9.9E-17 T 14-10-2018 IPR000362 Fumarate lyase family Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 PRINTS PR00149 Fumarate lyase superfamily signature 263 279 9.9E-17 T 14-10-2018 IPR000362 Fumarate lyase family Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 Gene3D G3DSA:1.10.40.30 349 385 3.9E-85 T 14-10-2018 Theos_1383 668a3d8cdc1b425be6e343d38f59fc82 468 SUPERFAMILY SSF48557 20 431 1.88E-73 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 Theos_1612 af2188a4296bf60a3ea1da2d8ea119da 189 Pfam PF00005 ABC transporter 18 141 2.9E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1612 af2188a4296bf60a3ea1da2d8ea119da 189 ProSitePatterns PS00211 ABC transporters family signature. 115 129 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1612 af2188a4296bf60a3ea1da2d8ea119da 189 Gene3D G3DSA:3.40.50.300 1 189 1.6E-48 T 14-10-2018 Theos_1612 af2188a4296bf60a3ea1da2d8ea119da 189 SUPERFAMILY SSF52540 2 186 1.42E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1612 af2188a4296bf60a3ea1da2d8ea119da 189 SMART SM00382 27 189 4.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2362 417e5f1c67f64382affeae2abd9140a3 298 Gene3D G3DSA:3.40.50.1980 31 153 3.1E-39 T 14-10-2018 Theos_2362 417e5f1c67f64382affeae2abd9140a3 298 SUPERFAMILY SSF53807 15 283 3.1E-49 T 14-10-2018 Theos_2362 417e5f1c67f64382affeae2abd9140a3 298 Pfam PF01497 Periplasmic binding protein 36 266 8.1E-29 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain Theos_2362 417e5f1c67f64382affeae2abd9140a3 298 Gene3D G3DSA:3.40.50.1980 154 287 3.0E-42 T 14-10-2018 Theos_1831 c8ca2f2918500cbb5cf2807576a704e2 208 Gene3D G3DSA:3.30.70.260 128 197 6.0E-5 T 14-10-2018 Theos_1831 c8ca2f2918500cbb5cf2807576a704e2 208 SUPERFAMILY SSF55021 137 202 7.2E-9 T 14-10-2018 Theos_1831 c8ca2f2918500cbb5cf2807576a704e2 208 Pfam PF01842 ACT domain 136 195 1.8E-9 T 14-10-2018 IPR002912 ACT domain Theos_1831 c8ca2f2918500cbb5cf2807576a704e2 208 SMART SM00116 78 125 5.3E-12 T 14-10-2018 IPR000644 CBS domain Theos_1831 c8ca2f2918500cbb5cf2807576a704e2 208 SMART SM00116 10 57 4.7E-14 T 14-10-2018 IPR000644 CBS domain Theos_1831 c8ca2f2918500cbb5cf2807576a704e2 208 SUPERFAMILY SSF54631 1 127 1.39E-35 T 14-10-2018 Theos_1831 c8ca2f2918500cbb5cf2807576a704e2 208 Gene3D G3DSA:3.10.580.10 1 127 1.3E-37 T 14-10-2018 Theos_1831 c8ca2f2918500cbb5cf2807576a704e2 208 Pfam PF00571 CBS domain 71 125 1.1E-13 T 14-10-2018 IPR000644 CBS domain Theos_1831 c8ca2f2918500cbb5cf2807576a704e2 208 Pfam PF00571 CBS domain 3 55 2.5E-15 T 14-10-2018 IPR000644 CBS domain Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 Gene3D G3DSA:3.40.50.1440 2 309 2.1E-112 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 SUPERFAMILY SSF52490 5 197 1.31E-69 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 SUPERFAMILY SSF55307 196 313 1.21E-33 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 SMART SM00864 5 197 4.9E-114 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 SMART SM00865 199 317 1.0E-37 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 ProSitePatterns PS01134 FtsZ protein signature 1. 36 70 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 Pfam PF12327 FtsZ family, C-terminal domain 214 308 3.7E-23 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 5 164 3.9E-43 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 3 313 3.0E-121 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 1 324 37.513 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 ProSitePatterns PS01135 FtsZ protein signature 2. 89 110 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 PRINTS PR00423 Cell division protein FtsZ signature 90 110 2.7E-47 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 PRINTS PR00423 Cell division protein FtsZ signature 204 225 2.7E-47 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 PRINTS PR00423 Cell division protein FtsZ signature 181 203 2.7E-47 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Theos_1132 baf6a044d55f35df45c554e9bfaa0ea7 352 PRINTS PR00423 Cell division protein FtsZ signature 118 139 2.7E-47 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Theos_0727 2df069ce00e02a720b9d42623e8055a0 311 SUPERFAMILY SSF55326 9 139 5.23E-26 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Theos_0727 2df069ce00e02a720b9d42623e8055a0 311 Pfam PF02769 AIR synthase related protein, C-terminal domain 150 298 2.5E-6 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Theos_0727 2df069ce00e02a720b9d42623e8055a0 311 SUPERFAMILY SSF56042 147 307 4.49E-19 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Theos_0727 2df069ce00e02a720b9d42623e8055a0 311 Gene3D G3DSA:3.90.650.10 145 311 1.4E-41 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Theos_0727 2df069ce00e02a720b9d42623e8055a0 311 Pfam PF00586 AIR synthase related protein, N-terminal domain 31 138 4.0E-14 T 14-10-2018 IPR016188 PurM-like, N-terminal domain Theos_0727 2df069ce00e02a720b9d42623e8055a0 311 Gene3D G3DSA:3.30.1330.10 1 142 2.1E-32 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Theos_0727 2df069ce00e02a720b9d42623e8055a0 311 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 6 311 20.66 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Theos_0727 2df069ce00e02a720b9d42623e8055a0 311 PIRSF PIRSF005303 1 311 2.1E-60 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 Pfam PF13416 Bacterial extracellular solute-binding protein 39 334 1.4E-47 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 Gene3D G3DSA:3.40.190.10 133 370 1.4E-141 T 14-10-2018 Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 PRINTS PR00181 Maltose binding protein signature 145 164 6.4E-15 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 PRINTS PR00181 Maltose binding protein signature 165 184 6.4E-15 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 PRINTS PR00181 Maltose binding protein signature 61 79 6.4E-15 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 PRINTS PR00181 Maltose binding protein signature 230 249 6.4E-15 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 PRINTS PR00181 Maltose binding protein signature 124 143 6.4E-15 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 PRINTS PR00181 Maltose binding protein signature 354 373 6.4E-15 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 SUPERFAMILY SSF53850 20 392 1.19E-84 T 14-10-2018 Theos_0317 5594e8663639c7acccd23b522b3f2ea2 398 Gene3D G3DSA:3.40.190.10 35 354 1.4E-141 T 14-10-2018 Theos_0239 67bec06041d45c9b5ef54e3b0498e878 207 Gene3D G3DSA:3.40.190.10 7 198 4.1E-67 T 14-10-2018 Theos_0239 67bec06041d45c9b5ef54e3b0498e878 207 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 181 2.5E-49 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Theos_0239 67bec06041d45c9b5ef54e3b0498e878 207 SUPERFAMILY SSF53850 4 202 6.95E-56 T 14-10-2018 Theos_0239 67bec06041d45c9b5ef54e3b0498e878 207 Pfam PF01634 ATP phosphoribosyltransferase 53 201 1.9E-41 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Theos_0239 67bec06041d45c9b5ef54e3b0498e878 207 Gene3D G3DSA:3.40.190.10 94 176 4.1E-67 T 14-10-2018 Theos_0239 67bec06041d45c9b5ef54e3b0498e878 207 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 5 205 45.273 T 14-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 Theos_0239 67bec06041d45c9b5ef54e3b0498e878 207 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 140 161 - T 14-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 Theos_1851 85127821a6f8310621f91fb65cf26d74 607 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 204 6.8E-75 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_1851 85127821a6f8310621f91fb65cf26d74 607 SMART SM00790 5 206 3.4E-121 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_1851 85127821a6f8310621f91fb65cf26d74 607 Gene3D G3DSA:1.10.569.10 247 430 9.0E-123 T 14-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 Theos_1851 85127821a6f8310621f91fb65cf26d74 607 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 238 601 1.5E-122 T 14-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_1851 85127821a6f8310621f91fb65cf26d74 607 SUPERFAMILY SSF56228 3 207 7.32E-74 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Theos_1851 85127821a6f8310621f91fb65cf26d74 607 SUPERFAMILY SSF48310 213 601 6.15E-123 T 14-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Theos_1851 85127821a6f8310621f91fb65cf26d74 607 Gene3D G3DSA:3.60.9.10 2 209 1.7E-81 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Theos_1851 85127821a6f8310621f91fb65cf26d74 607 Gene3D G3DSA:1.10.599.10 246 601 9.0E-123 T 14-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 Theos_1857 b94881136ab363fb03c8208f1fd2abbe 91 Gene3D G3DSA:1.10.10.10 1 90 7.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1857 b94881136ab363fb03c8208f1fd2abbe 91 Pfam PF13601 Winged helix DNA-binding domain 7 87 1.4E-25 T 14-10-2018 IPR027395 Winged helix DNA-binding domain Theos_1857 b94881136ab363fb03c8208f1fd2abbe 91 SUPERFAMILY SSF46785 4 87 9.0E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0338 0eb55e2b3bb34c67aebf89054bb21fef 165 Pfam PF12867 DinB superfamily 26 155 2.1E-13 T 14-10-2018 IPR024775 DinB-like domain Theos_0338 0eb55e2b3bb34c67aebf89054bb21fef 165 SUPERFAMILY SSF109854 3 163 7.33E-28 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes Theos_0338 0eb55e2b3bb34c67aebf89054bb21fef 165 Gene3D G3DSA:1.20.120.450 5 163 5.2E-25 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes Theos_0668 0655efb9a9825e4fc7b190d844b401fc 375 SMART SM00471 71 209 6.8E-13 T 14-10-2018 IPR003607 HD/PDEase domain Theos_0668 0655efb9a9825e4fc7b190d844b401fc 375 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 38 172 5.0E-60 T 14-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 Theos_0668 0655efb9a9825e4fc7b190d844b401fc 375 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 15 374 38.023 T 14-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 Theos_0668 0655efb9a9825e4fc7b190d844b401fc 375 Pfam PF01966 HD domain 75 199 2.2E-17 T 14-10-2018 IPR006674 HD domain Theos_0668 0655efb9a9825e4fc7b190d844b401fc 375 Pfam PF13286 Phosphohydrolase-associated domain 287 372 1.7E-25 T 14-10-2018 IPR026875 Phosphohydrolase-associated domain Theos_0668 0655efb9a9825e4fc7b190d844b401fc 375 Gene3D G3DSA:1.10.3210.10 3 375 4.6E-153 T 14-10-2018 Theos_0668 0655efb9a9825e4fc7b190d844b401fc 375 SUPERFAMILY SSF109604 26 372 3.93E-84 T 14-10-2018 Theos_0104 2a3b04166b26ff3172af3bb8b67dddd0 407 Gene3D G3DSA:3.40.190.10 143 402 8.9E-85 T 14-10-2018 Theos_0104 2a3b04166b26ff3172af3bb8b67dddd0 407 SUPERFAMILY SSF53850 28 404 2.01E-73 T 14-10-2018 Theos_0104 2a3b04166b26ff3172af3bb8b67dddd0 407 Pfam PF13416 Bacterial extracellular solute-binding protein 46 339 1.7E-32 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_0104 2a3b04166b26ff3172af3bb8b67dddd0 407 Gene3D G3DSA:3.40.190.10 31 366 8.9E-85 T 14-10-2018 Theos_2270 38a1c5f3f314b590627d553c8c859967 347 SUPERFAMILY SSF52540 25 166 1.12E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2270 38a1c5f3f314b590627d553c8c859967 347 Pfam PF07728 AAA domain (dynein-related subfamily) 28 123 1.8E-7 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Theos_2270 38a1c5f3f314b590627d553c8c859967 347 Gene3D G3DSA:3.40.50.300 18 169 2.9E-18 T 14-10-2018 Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 9 369 1.6E-103 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 PIRSF PIRSF006769 1 376 3.7E-126 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 Gene3D G3DSA:3.40.140.10 2 140 5.8E-44 T 14-10-2018 Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 Pfam PF01872 RibD C-terminal domain 147 368 1.0E-43 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 Gene3D G3DSA:3.40.430.10 141 375 1.9E-63 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 1.8E-19 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 146 373 5.9E-48 T 14-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 SUPERFAMILY SSF53927 4 144 8.66E-46 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Theos_1167 6012b9dad5a7381a8ba5796488a03f0a 376 SUPERFAMILY SSF53597 145 373 9.32E-53 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Theos_1883 d981e7188cbcc71c8a396c7a0f1a9376 338 Gene3D G3DSA:3.40.1010.20 15 303 5.0E-96 T 14-10-2018 Theos_1883 d981e7188cbcc71c8a396c7a0f1a9376 338 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 9 308 34.452 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Theos_1883 d981e7188cbcc71c8a396c7a0f1a9376 338 Gene3D G3DSA:3.40.1010.20 112 218 5.0E-96 T 14-10-2018 Theos_1883 d981e7188cbcc71c8a396c7a0f1a9376 338 Pfam PF02401 LytB protein 11 304 6.0E-82 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Theos_1883 d981e7188cbcc71c8a396c7a0f1a9376 338 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 11 306 4.2E-91 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Theos_1883 d981e7188cbcc71c8a396c7a0f1a9376 338 Gene3D G3DSA:3.40.50.11270 20 111 5.0E-96 T 14-10-2018 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 107 199 3.1E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 PIRSF PIRSF016578 5 347 3.4E-22 T 14-10-2018 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 109 121 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 Gene3D G3DSA:2.40.110.10 107 214 7.5E-33 T 14-10-2018 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 210 357 1.8E-48 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 SUPERFAMILY SSF47203 210 360 3.06E-51 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 Gene3D G3DSA:1.10.540.10 1 104 8.6E-23 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 Gene3D G3DSA:1.20.140.10 215 365 7.8E-51 T 14-10-2018 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 2 92 2.3E-18 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Theos_1176 f2d8ce6083bb97d336c256d6ca64276f 366 SUPERFAMILY SSF56645 2 209 1.31E-55 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Theos_2316 a4fdb902bd753b61f8ad69ec0352f66b 366 Pfam PF01888 CbiD 15 266 4.1E-86 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Theos_2316 a4fdb902bd753b61f8ad69ec0352f66b 366 Gene3D G3DSA:3.30.2110.10 16 180 1.7E-48 T 14-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Theos_2316 a4fdb902bd753b61f8ad69ec0352f66b 366 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 14 359 27.746 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Theos_2316 a4fdb902bd753b61f8ad69ec0352f66b 366 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 21 335 4.3E-54 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Theos_2316 a4fdb902bd753b61f8ad69ec0352f66b 366 PIRSF PIRSF026782 10 362 6.0E-111 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Theos_2316 a4fdb902bd753b61f8ad69ec0352f66b 366 SUPERFAMILY SSF111342 9 283 1.57E-82 T 14-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Theos_1264 b86cfe5b58cfc0b3d8e789db5adf44d7 101 SUPERFAMILY SSF46785 8 94 8.93E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1264 b86cfe5b58cfc0b3d8e789db5adf44d7 101 Gene3D G3DSA:1.10.10.10 2 101 1.0E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1264 b86cfe5b58cfc0b3d8e789db5adf44d7 101 Pfam PF01638 HxlR-like helix-turn-helix 21 94 6.4E-19 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type Theos_0933 7ed0a2fd2fcd4873b6add11f60562dc9 374 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 4 330 3.3E-99 T 14-10-2018 IPR010148 CRISPR-associated protein, CT1975 Theos_0933 7ed0a2fd2fcd4873b6add11f60562dc9 374 Pfam PF09344 CT1975-like protein 5 334 1.1E-120 T 14-10-2018 IPR010148 CRISPR-associated protein, CT1975 Theos_0285 bcbe40a8bd663cc7afde168ff50e1445 72 SUPERFAMILY SSF46561 11 70 5.49E-17 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0285 bcbe40a8bd663cc7afde168ff50e1445 72 TIGRFAM TIGR00012 L29: ribosomal protein uL29 14 67 1.2E-20 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0285 bcbe40a8bd663cc7afde168ff50e1445 72 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 6 67 15.647 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0285 bcbe40a8bd663cc7afde168ff50e1445 72 Pfam PF00831 Ribosomal L29 protein 12 67 6.9E-19 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0285 bcbe40a8bd663cc7afde168ff50e1445 72 Gene3D G3DSA:1.20.58.1890 1 72 1.9E-29 T 14-10-2018 Theos_0801 419c02ef55dc334fd8c09ac257be8e7b 205 SUPERFAMILY SSF53271 26 196 1.44E-18 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_0801 419c02ef55dc334fd8c09ac257be8e7b 205 Gene3D G3DSA:3.40.50.2020 66 201 1.0E-11 T 14-10-2018 Theos_1900 87e1436077e0814bc0ab27dc9d22dec9 160 SUPERFAMILY SSF55040 9 153 6.8E-56 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1900 87e1436077e0814bc0ab27dc9d22dec9 160 Gene3D G3DSA:3.30.70.640 1 157 7.7E-67 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1900 87e1436077e0814bc0ab27dc9d22dec9 160 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 7 150 4.8E-56 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1900 87e1436077e0814bc0ab27dc9d22dec9 160 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 1 156 34.586 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_1900 87e1436077e0814bc0ab27dc9d22dec9 160 Pfam PF01967 MoaC family 13 148 3.7E-51 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Theos_2378 585f782090421e509aafd2cd628d49aa 393 Gene3D G3DSA:2.130.10.10 27 226 2.6E-12 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Theos_2378 585f782090421e509aafd2cd628d49aa 393 SUPERFAMILY SSF50969 36 384 1.15E-17 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Theos_0341 69d263b60ec366464d7e3ca805d4a3a6 114 SUPERFAMILY SSF103196 2 114 2.88E-20 T 14-10-2018 Theos_0341 69d263b60ec366464d7e3ca805d4a3a6 114 Gene3D G3DSA:3.30.450.30 1 114 2.6E-19 T 14-10-2018 Theos_0341 69d263b60ec366464d7e3ca805d4a3a6 114 Pfam PF03259 Roadblock/LC7 domain 1 87 1.4E-12 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain Theos_0341 69d263b60ec366464d7e3ca805d4a3a6 114 SMART SM00960 1 90 4.2E-15 T 14-10-2018 IPR004942 Roadblock/LAMTOR2 domain Theos_0271 b3accf614f37f7fc544d2fd9deccf6d9 539 Pfam PF14326 Domain of unknown function (DUF4384) 55 135 4.1E-29 T 14-10-2018 IPR025493 Domain of unknown function DUF4384 Theos_0271 b3accf614f37f7fc544d2fd9deccf6d9 539 SUPERFAMILY SSF49452 494 535 2.55E-5 T 14-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 Theos_0271 b3accf614f37f7fc544d2fd9deccf6d9 539 Pfam PF08308 PEGA domain 481 536 4.7E-8 T 14-10-2018 IPR013229 PEGA Theos_0271 b3accf614f37f7fc544d2fd9deccf6d9 539 Pfam PF08308 PEGA domain 262 329 2.0E-19 T 14-10-2018 IPR013229 PEGA Theos_0271 b3accf614f37f7fc544d2fd9deccf6d9 539 Pfam PF08308 PEGA domain 403 467 2.7E-18 T 14-10-2018 IPR013229 PEGA Theos_0271 b3accf614f37f7fc544d2fd9deccf6d9 539 Pfam PF08308 PEGA domain 333 400 4.1E-19 T 14-10-2018 IPR013229 PEGA Theos_0271 b3accf614f37f7fc544d2fd9deccf6d9 539 Pfam PF08308 PEGA domain 191 256 2.2E-16 T 14-10-2018 IPR013229 PEGA Theos_0271 b3accf614f37f7fc544d2fd9deccf6d9 539 Gene3D G3DSA:2.60.40.1120 353 398 2.6E-5 T 14-10-2018 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 PRINTS PR00385 P450 superfamily signature 337 348 1.8E-12 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 PRINTS PR00385 P450 superfamily signature 257 268 1.8E-12 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 PRINTS PR00385 P450 superfamily signature 222 239 1.8E-12 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 PRINTS PR00385 P450 superfamily signature 328 337 1.8E-12 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 SUPERFAMILY SSF48264 18 384 2.75E-66 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 Pfam PF00067 Cytochrome P450 14 181 2.3E-5 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 Pfam PF00067 Cytochrome P450 208 365 6.5E-32 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 330 339 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 PRINTS PR00463 E-class P450 group I signature 294 318 2.9E-10 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 PRINTS PR00463 E-class P450 group I signature 211 228 2.9E-10 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 PRINTS PR00463 E-class P450 group I signature 231 257 2.9E-10 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 PRINTS PR00463 E-class P450 group I signature 337 360 2.9E-10 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 PRINTS PR00463 E-class P450 group I signature 327 337 2.9E-10 T 14-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_1148 8665acf40fd4cc136effe5df633a56d6 387 Gene3D G3DSA:1.10.630.10 3 386 1.2E-126 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 Theos_2206 04a13115e3818bd7630f41f16edfca99 596 SMART SM01228 520 591 1.6E-34 T 14-10-2018 Theos_2206 04a13115e3818bd7630f41f16edfca99 596 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 4 594 1.4E-207 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 Theos_2206 04a13115e3818bd7630f41f16edfca99 596 Gene3D G3DSA:1.10.10.1800 477 542 1.0E-6 T 14-10-2018 Theos_2206 04a13115e3818bd7630f41f16edfca99 596 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 2 596 36.906 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 Theos_2206 04a13115e3818bd7630f41f16edfca99 596 Gene3D G3DSA:1.10.150.570 543 596 4.3E-19 T 14-10-2018 Theos_2206 04a13115e3818bd7630f41f16edfca99 596 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 362 385 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Theos_2206 04a13115e3818bd7630f41f16edfca99 596 SUPERFAMILY SSF51905 1 254 7.6E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2206 04a13115e3818bd7630f41f16edfca99 596 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 267 281 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Theos_2206 04a13115e3818bd7630f41f16edfca99 596 Gene3D G3DSA:3.50.50.60 306 452 2.5E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2206 04a13115e3818bd7630f41f16edfca99 596 Gene3D G3DSA:3.50.50.60 1 215 2.7E-74 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_2206 04a13115e3818bd7630f41f16edfca99 596 Pfam PF13932 GidA associated domain 396 590 4.8E-60 T 14-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 Theos_2206 04a13115e3818bd7630f41f16edfca99 596 Pfam PF01134 Glucose inhibited division protein A 5 391 2.6E-140 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 Theos_1262 5eee160c0bc411656f7c68cdb7de398b 74 Gene3D G3DSA:3.30.1070.10 11 73 5.6E-14 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 Theos_1262 5eee160c0bc411656f7c68cdb7de398b 74 Pfam PF03776 Septum formation topological specificity factor MinE 7 73 1.1E-20 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 Theos_1262 5eee160c0bc411656f7c68cdb7de398b 74 SUPERFAMILY SSF55229 23 73 7.85E-10 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 Theos_1262 5eee160c0bc411656f7c68cdb7de398b 74 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 5 73 3.6E-22 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 Theos_0183 7f1c740c06b9dc289dc5c0760a62327b 141 Pfam PF07977 FabA-like domain 10 128 5.6E-30 T 14-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Theos_0183 7f1c740c06b9dc289dc5c0760a62327b 141 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 1 137 7.5E-50 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Theos_0183 7f1c740c06b9dc289dc5c0760a62327b 141 Gene3D G3DSA:3.10.129.10 1 140 1.9E-52 T 14-10-2018 Theos_0183 7f1c740c06b9dc289dc5c0760a62327b 141 SUPERFAMILY SSF54637 3 137 2.61E-44 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_0183 7f1c740c06b9dc289dc5c0760a62327b 141 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 1 140 31.601 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Theos_1614 26e6974279289b14aaf9e52d63a7d63d 182 Gene3D G3DSA:1.10.760.10 33 165 5.7E-45 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1614 26e6974279289b14aaf9e52d63a7d63d 182 SUPERFAMILY SSF46626 38 160 9.46E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1614 26e6974279289b14aaf9e52d63a7d63d 182 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 54 137 2.4E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0713 ab9fc2de4260af6f5fca33d8fc8a46ae 405 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 14 405 48.479 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0713 ab9fc2de4260af6f5fca33d8fc8a46ae 405 Gene3D G3DSA:1.10.645.20 22 405 9.5E-173 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0713 ab9fc2de4260af6f5fca33d8fc8a46ae 405 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 21 405 5.8E-169 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0713 ab9fc2de4260af6f5fca33d8fc8a46ae 405 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 135 405 1.3E-112 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0713 ab9fc2de4260af6f5fca33d8fc8a46ae 405 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 58 69 - T 14-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0713 ab9fc2de4260af6f5fca33d8fc8a46ae 405 SUPERFAMILY SSF56762 31 405 8.77E-134 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0841 7a6c8b588cb2c4807010fa9d2c1c2c54 364 Pfam PF04389 Peptidase family M28 182 337 4.1E-13 T 14-10-2018 IPR007484 Peptidase M28 Theos_0841 7a6c8b588cb2c4807010fa9d2c1c2c54 364 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 114 123 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Theos_0841 7a6c8b588cb2c4807010fa9d2c1c2c54 364 SUPERFAMILY SSF53187 9 343 2.88E-22 T 14-10-2018 Theos_0448 5963bf7dfd4d12f15280e187f5f899ac 140 Pfam PF02566 OsmC-like protein 36 131 2.6E-18 T 14-10-2018 IPR003718 OsmC/Ohr family Theos_0448 5963bf7dfd4d12f15280e187f5f899ac 140 Gene3D G3DSA:3.30.300.20 3 135 5.7E-33 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_0448 5963bf7dfd4d12f15280e187f5f899ac 140 SUPERFAMILY SSF82784 7 135 5.5E-35 T 14-10-2018 IPR036102 OsmC/Ohr superfamily Theos_1838 064f0518f601a285f7f679407a13fb2a 335 Gene3D G3DSA:3.50.50.60 125 247 8.0E-119 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.4E-23 T 14-10-2018 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 3.4E-23 T 14-10-2018 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 3.4E-23 T 14-10-2018 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 3.4E-23 T 14-10-2018 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.4E-23 T 14-10-2018 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 1.1E-27 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.1E-27 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 1.1E-27 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 148 172 1.1E-27 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 1.1E-27 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 287 2.9E-35 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 Hamap MF_01685 Ferredoxin--NADP reductase. 3 328 42.897 T 14-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 Theos_1838 064f0518f601a285f7f679407a13fb2a 335 SUPERFAMILY SSF51905 1 313 1.3E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1838 064f0518f601a285f7f679407a13fb2a 335 Gene3D G3DSA:3.50.50.60 5 308 8.0E-119 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1382 fc06775d54faca93956a49dd313e22b1 354 Pfam PF03595 Voltage-dependent anion channel 7 327 2.3E-54 T 14-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 Theos_1382 fc06775d54faca93956a49dd313e22b1 354 Gene3D G3DSA:1.50.10.150 2 337 1.3E-31 T 14-10-2018 IPR038665 Voltage-dependent anion channel superfamily Theos_0645 53cfa1e89bfd6672550c7627beb81aaf 163 Hamap MF_00042 Ribonuclease H [rnhA]. 5 154 38.07 T 14-10-2018 IPR022892 Ribonuclease HI GO:0004523 Theos_0645 53cfa1e89bfd6672550c7627beb81aaf 163 SUPERFAMILY SSF53098 7 145 1.64E-54 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_0645 53cfa1e89bfd6672550c7627beb81aaf 163 Pfam PF00075 RNase H 6 145 1.6E-44 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 Theos_0645 53cfa1e89bfd6672550c7627beb81aaf 163 Gene3D G3DSA:3.30.420.10 2 159 1.4E-58 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Theos_2030 c5c7231124522d8c1161ed6e37f12626 326 Gene3D G3DSA:3.40.718.10 1 325 7.7E-120 T 14-10-2018 Theos_2030 c5c7231124522d8c1161ed6e37f12626 326 Pfam PF02504 Fatty acid synthesis protein 1 315 1.2E-102 T 14-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 Theos_2030 c5c7231124522d8c1161ed6e37f12626 326 SUPERFAMILY SSF53659 1 324 2.51E-89 T 14-10-2018 Theos_2030 c5c7231124522d8c1161ed6e37f12626 326 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 326 128.213 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 Theos_2030 c5c7231124522d8c1161ed6e37f12626 326 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 324 7.4E-96 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 Theos_2030 c5c7231124522d8c1161ed6e37f12626 326 PIRSF PIRSF002465 1 326 1.0E-111 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 SUPERFAMILY SSF143724 99 274 1.88E-10 T 14-10-2018 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 Gene3D G3DSA:3.30.1840.10 5 274 9.8E-33 T 14-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 SUPERFAMILY SSF56024 476 609 3.36E-33 T 14-10-2018 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 Pfam PF13089 Polyphosphate kinase N-terminal domain 11 56 4.4E-17 T 14-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 Pfam PF02503 Polyphosphate kinase middle domain 152 288 7.1E-9 T 14-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 SUPERFAMILY SSF56024 296 449 4.71E-35 T 14-10-2018 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 SUPERFAMILY SSF140356 9 57 1.31E-18 T 14-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 Pfam PF13090 Polyphosphate kinase C-terminal domain 298 604 2.4E-80 T 14-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 Gene3D G3DSA:3.30.870.10 291 458 8.9E-44 T 14-10-2018 Theos_2381 3a24110b3e4bbd9f156b6d1d8067b10d 619 Gene3D G3DSA:3.30.870.10 465 616 2.9E-34 T 14-10-2018 Theos_1722 a9d3fb7a5968f1019f7e8fe296c8def1 378 Pfam PF07690 Major Facilitator Superfamily 9 340 1.1E-20 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_1722 a9d3fb7a5968f1019f7e8fe296c8def1 378 Gene3D G3DSA:1.20.1250.20 195 378 5.6E-17 T 14-10-2018 Theos_1722 a9d3fb7a5968f1019f7e8fe296c8def1 378 SUPERFAMILY SSF103473 5 375 5.62E-32 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1722 a9d3fb7a5968f1019f7e8fe296c8def1 378 Gene3D G3DSA:1.20.1250.20 3 182 2.1E-8 T 14-10-2018 Theos_1067 a7e9d42013cffae5dcb3fef8743fb67c 340 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 46 176 3.1E-64 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Theos_1067 a7e9d42013cffae5dcb3fef8743fb67c 340 Gene3D G3DSA:3.40.50.300 9 209 1.6E-51 T 14-10-2018 Theos_1067 a7e9d42013cffae5dcb3fef8743fb67c 340 SUPERFAMILY SSF52540 11 294 8.54E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1067 a7e9d42013cffae5dcb3fef8743fb67c 340 PIRSF PIRSF002849 1 323 1.2E-130 T 14-10-2018 Theos_1067 a7e9d42013cffae5dcb3fef8743fb67c 340 Gene3D G3DSA:1.10.8.300 210 318 6.0E-33 T 14-10-2018 Theos_2139 0ad3de76dfe6897f4fcf121f57c475eb 179 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 160 2.0E-26 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ Theos_0375 d3ba8e2dd3ea124bac7582c1a817ebac 117 Pfam PF09862 Protein of unknown function (DUF2089) 5 115 1.9E-40 T 14-10-2018 IPR018658 Protein of unknown function DUF2089 Theos_1196 183b458db43a7574a477be8ae093a03d 260 SUPERFAMILY SSF56112 12 255 1.38E-40 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Theos_1196 183b458db43a7574a477be8ae093a03d 260 PIRSF PIRSF006221 11 260 2.7E-45 T 14-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 Theos_1196 183b458db43a7574a477be8ae093a03d 260 Gene3D G3DSA:3.90.1200.10 80 260 2.0E-41 T 14-10-2018 Theos_1196 183b458db43a7574a477be8ae093a03d 260 Gene3D G3DSA:3.30.200.20 3 76 6.0E-12 T 14-10-2018 Theos_1196 183b458db43a7574a477be8ae093a03d 260 Pfam PF03881 Fructosamine kinase 16 258 5.2E-46 T 14-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 Theos_0844 8e1b00c8b84a45190fa20c8f19be0932 288 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 8 285 2.6E-95 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Theos_0844 8e1b00c8b84a45190fa20c8f19be0932 288 SUPERFAMILY SSF53850 8 287 3.37E-78 T 14-10-2018 Theos_0844 8e1b00c8b84a45190fa20c8f19be0932 288 Pfam PF16868 NMT1-like family 8 285 8.8E-76 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Theos_0844 8e1b00c8b84a45190fa20c8f19be0932 288 Gene3D G3DSA:3.40.190.10 8 285 1.8E-112 T 14-10-2018 Theos_0844 8e1b00c8b84a45190fa20c8f19be0932 288 Gene3D G3DSA:3.40.190.10 83 221 1.8E-112 T 14-10-2018 Theos_1331 c9f20b4549caabfc245e19d4a61efebd 185 SUPERFAMILY SSF55194 5 184 1.16E-67 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 Theos_1331 c9f20b4549caabfc245e19d4a61efebd 185 Gene3D G3DSA:1.10.132.20 13 183 2.8E-70 T 14-10-2018 Theos_1331 c9f20b4549caabfc245e19d4a61efebd 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 185 26.003 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 Theos_1331 c9f20b4549caabfc245e19d4a61efebd 185 Gene3D G3DSA:3.30.1360.40 32 106 2.8E-70 T 14-10-2018 Theos_1331 c9f20b4549caabfc245e19d4a61efebd 185 Pfam PF01765 Ribosome recycling factor 21 184 9.8E-64 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 Theos_1331 c9f20b4549caabfc245e19d4a61efebd 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 184 3.7E-67 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 428 29.124 T 14-10-2018 IPR026593 Protein translocase subunit SecY Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 424 9.9E-113 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 Pfam PF00344 SecY translocase 71 411 2.6E-104 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 Gene3D G3DSA:1.10.3370.10 1 424 3.1E-185 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PIRSF PIRSF004557 1 434 5.5E-115 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 SUPERFAMILY SSF103491 1 419 6.93E-115 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 177 200 3.2E-77 T 14-10-2018 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 111 134 3.2E-77 T 14-10-2018 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 70 90 3.2E-77 T 14-10-2018 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 3.2E-77 T 14-10-2018 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 3.2E-77 T 14-10-2018 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 3.2E-77 T 14-10-2018 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 151 176 3.2E-77 T 14-10-2018 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 3.2E-77 T 14-10-2018 Theos_0297 9bf0105cdaa9e01b916472abf617f674 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 3.2E-77 T 14-10-2018 Theos_0956 743210eb47b703121aa571001214f9d2 152 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 7.5E-56 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 Theos_0956 743210eb47b703121aa571001214f9d2 152 SUPERFAMILY SSF69500 1 145 3.79E-56 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily Theos_0956 743210eb47b703121aa571001214f9d2 152 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 146 1.0E-55 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 Theos_0956 743210eb47b703121aa571001214f9d2 152 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.317 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 Theos_0956 743210eb47b703121aa571001214f9d2 152 Gene3D G3DSA:3.50.80.10 1 148 6.3E-57 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily Theos_1737 81391e86de92897d1a65d10df6f61d04 301 Pfam PF03466 LysR substrate binding domain 100 299 1.6E-53 T 14-10-2018 IPR005119 LysR, substrate-binding Theos_1737 81391e86de92897d1a65d10df6f61d04 301 Gene3D G3DSA:1.10.10.10 8 94 8.9E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1737 81391e86de92897d1a65d10df6f61d04 301 Gene3D G3DSA:3.40.190.290 100 300 5.1E-48 T 14-10-2018 Theos_1737 81391e86de92897d1a65d10df6f61d04 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 5.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_1737 81391e86de92897d1a65d10df6f61d04 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 5.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_1737 81391e86de92897d1a65d10df6f61d04 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 5.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_1737 81391e86de92897d1a65d10df6f61d04 301 SUPERFAMILY SSF53850 100 299 6.27E-50 T 14-10-2018 Theos_1737 81391e86de92897d1a65d10df6f61d04 301 SUPERFAMILY SSF46785 5 120 2.2E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1737 81391e86de92897d1a65d10df6f61d04 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 71 5.7E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Theos_0194 14bc3558f9435d841efad2feded8e103 233 SUPERFAMILY SSF49344 3 197 3.92E-32 T 14-10-2018 Theos_0194 14bc3558f9435d841efad2feded8e103 233 Gene3D G3DSA:2.60.40.1190 3 194 1.8E-12 T 14-10-2018 Theos_0194 14bc3558f9435d841efad2feded8e103 233 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 5 195 2.9E-16 T 14-10-2018 IPR019248 Glucodextranase-like, C-terminal Theos_1541 5e51b17493c77bd74bc02d373346eac1 492 Gene3D G3DSA:3.40.605.10 21 485 4.5E-190 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Theos_1541 5e51b17493c77bd74bc02d373346eac1 492 Gene3D G3DSA:3.40.309.10 267 457 4.5E-190 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Theos_1541 5e51b17493c77bd74bc02d373346eac1 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Theos_1541 5e51b17493c77bd74bc02d373346eac1 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 290 301 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Theos_1541 5e51b17493c77bd74bc02d373346eac1 492 SUPERFAMILY SSF53720 10 490 9.82E-178 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Theos_1541 5e51b17493c77bd74bc02d373346eac1 492 Pfam PF00171 Aldehyde dehydrogenase family 27 487 2.6E-180 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Theos_0731 e789d29a171fcba4cfaf00260e7ad1ef 198 Gene3D G3DSA:3.40.50.880 1 198 3.9E-64 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_0731 e789d29a171fcba4cfaf00260e7ad1ef 198 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 194 30.377 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Theos_0731 e789d29a171fcba4cfaf00260e7ad1ef 198 PIRSF PIRSF000495 1 196 2.6E-57 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Theos_0731 e789d29a171fcba4cfaf00260e7ad1ef 198 SUPERFAMILY SSF52317 2 188 6.59E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_0731 e789d29a171fcba4cfaf00260e7ad1ef 198 Pfam PF00117 Glutamine amidotransferase class-I 5 183 7.5E-10 T 14-10-2018 IPR017926 Glutamine amidotransferase Theos_0731 e789d29a171fcba4cfaf00260e7ad1ef 198 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 189 8.6E-50 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Theos_0934 48e34ebcc39106c5b786e7c7445ce44e 228 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 3 200 1.9E-51 T 14-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 Theos_0934 48e34ebcc39106c5b786e7c7445ce44e 228 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 45 1.7E-15 T 14-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal Theos_0934 48e34ebcc39106c5b786e7c7445ce44e 228 Gene3D G3DSA:3.30.70.2660 1 224 1.1E-84 T 14-10-2018 Theos_0934 48e34ebcc39106c5b786e7c7445ce44e 228 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 167 9.8E-46 T 14-10-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 Theos_1415 695cd6a95df3272137b7d11ce28d07a6 125 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 94 1.2E-10 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Theos_1415 695cd6a95df3272137b7d11ce28d07a6 125 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 125 6.0E-36 T 14-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 Theos_1415 695cd6a95df3272137b7d11ce28d07a6 125 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 89 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Theos_1415 695cd6a95df3272137b7d11ce28d07a6 125 Gene3D G3DSA:3.40.140.10 1 125 5.6E-37 T 14-10-2018 Theos_1415 695cd6a95df3272137b7d11ce28d07a6 125 SUPERFAMILY SSF53927 4 125 2.48E-35 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Theos_1362 1ca609c935a478337a90e90d43a8d476 148 Gene3D G3DSA:3.10.129.10 2 148 4.4E-58 T 14-10-2018 Theos_1362 1ca609c935a478337a90e90d43a8d476 148 SUPERFAMILY SSF54637 2 147 2.29E-48 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_1362 1ca609c935a478337a90e90d43a8d476 148 Pfam PF01575 MaoC like domain 9 115 1.2E-31 T 14-10-2018 IPR002539 MaoC-like dehydratase domain Theos_1362 1ca609c935a478337a90e90d43a8d476 148 PRINTS PR01483 Fatty acid synthase signature 117 136 1.3E-5 T 14-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 Theos_1362 1ca609c935a478337a90e90d43a8d476 148 PRINTS PR01483 Fatty acid synthase signature 23 45 1.3E-5 T 14-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 Theos_1362 1ca609c935a478337a90e90d43a8d476 148 PRINTS PR01483 Fatty acid synthase signature 45 66 1.3E-5 T 14-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 Theos_1477 df43115cb1fbc9d4f462a4cdc963b0ea 280 Pfam PF07466 Protein of unknown function (DUF1517) 19 279 3.4E-30 T 14-10-2018 IPR010903 Protein of unknown function DUF1517 Theos_1537 6a8e84c7d655b8efed97cbe2f85085b9 251 Gene3D G3DSA:1.25.40.10 35 236 6.9E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1537 6a8e84c7d655b8efed97cbe2f85085b9 251 SUPERFAMILY SSF48452 81 157 9.48E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0699 2847dfa9a603737e348e802fa523b962 150 Gene3D G3DSA:3.10.580.10 1 149 2.8E-39 T 14-10-2018 Theos_0699 2847dfa9a603737e348e802fa523b962 150 Pfam PF00571 CBS domain 92 146 1.6E-16 T 14-10-2018 IPR000644 CBS domain Theos_0699 2847dfa9a603737e348e802fa523b962 150 Pfam PF00571 CBS domain 3 54 1.3E-13 T 14-10-2018 IPR000644 CBS domain Theos_0699 2847dfa9a603737e348e802fa523b962 150 SUPERFAMILY SSF54631 1 147 5.18E-37 T 14-10-2018 Theos_0699 2847dfa9a603737e348e802fa523b962 150 SMART SM00116 10 58 3.7E-9 T 14-10-2018 IPR000644 CBS domain Theos_0699 2847dfa9a603737e348e802fa523b962 150 SMART SM00116 99 147 2.6E-15 T 14-10-2018 IPR000644 CBS domain Theos_1649 d2709b014af08dddce9894f1f8f68e8e 398 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 209 385 8.6E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1649 d2709b014af08dddce9894f1f8f68e8e 398 Gene3D G3DSA:1.10.3720.10 2 72 4.5E-6 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1649 d2709b014af08dddce9894f1f8f68e8e 398 Gene3D G3DSA:1.10.3720.10 154 390 1.4E-55 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1649 d2709b014af08dddce9894f1f8f68e8e 398 SUPERFAMILY SSF161098 3 398 1.96E-65 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2467 22fc769007d838d75a7d7197c0f3177f 400 SUPERFAMILY SSF103473 5 374 5.75E-55 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_2467 22fc769007d838d75a7d7197c0f3177f 400 Pfam PF07690 Major Facilitator Superfamily 8 336 3.5E-40 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_2467 22fc769007d838d75a7d7197c0f3177f 400 Gene3D G3DSA:1.20.1250.20 2 373 2.1E-46 T 14-10-2018 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Gene3D G3DSA:3.30.65.10 573 624 2.5E-7 T 14-10-2018 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Gene3D G3DSA:3.30.65.10 625 664 6.8E-9 T 14-10-2018 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 305 327 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 SUPERFAMILY SSF57783 627 661 2.38E-11 T 14-10-2018 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Pfam PF01131 DNA topoisomerase 142 569 1.3E-127 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 SMART SM00436 118 207 3.3E-46 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Hamap MF_00952 DNA topoisomerase 1 [topA]. 18 692 52.966 T 14-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Pfam PF01751 Toprim domain 19 127 1.9E-23 T 14-10-2018 IPR006171 TOPRIM domain Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Gene3D G3DSA:3.40.50.140 17 148 1.0E-47 T 14-10-2018 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Gene3D G3DSA:2.70.20.10 199 479 5.7E-158 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 SMART SM00493 18 117 1.8E-26 T 14-10-2018 IPR006171 TOPRIM domain Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Gene3D G3DSA:1.10.460.10 149 572 5.7E-158 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Gene3D G3DSA:1.10.290.10 276 411 5.7E-158 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 91 104 1.8E-37 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 495 509 1.8E-37 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 318 327 1.8E-37 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 177 195 1.8E-37 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 396 412 1.8E-37 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 20 620 5.6E-218 T 14-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 SUPERFAMILY SSF56712 19 596 6.41E-186 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 628 662 4.8E-15 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 669 700 6.6E-4 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 586 621 2.1E-13 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Theos_0416 332af179e9fc5067bad1ff5280584a07 819 SMART SM00437 268 532 1.8E-118 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 SMART SM00028 33 62 10.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 SMART SM00028 312 345 29.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 SMART SM00028 278 311 0.3 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 SMART SM00028 176 208 0.016 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 SMART SM00028 243 276 0.56 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 SMART SM00028 142 175 0.0062 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 Gene3D G3DSA:1.25.40.10 280 355 7.0E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 Gene3D G3DSA:1.25.40.10 218 279 2.8E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 Pfam PF14559 Tetratricopeptide repeat 186 244 2.5E-9 T 14-10-2018 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 Pfam PF14559 Tetratricopeptide repeat 39 94 5.3E-10 T 14-10-2018 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 Pfam PF14559 Tetratricopeptide repeat 122 184 1.9E-6 T 14-10-2018 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 Pfam PF13432 Tetratricopeptide repeat 284 344 7.4E-7 T 14-10-2018 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 Gene3D G3DSA:1.25.40.10 26 217 3.9E-57 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 SUPERFAMILY SSF48452 125 348 3.13E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1110 552a252d8b55cb69ebce496840412ad4 355 SUPERFAMILY SSF48452 34 167 5.69E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0293 06a4d78698860c9ab667b5727457392b 112 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 5 112 5.9E-40 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0293 06a4d78698860c9ab667b5727457392b 112 Gene3D G3DSA:3.30.420.100 1 112 4.2E-42 T 14-10-2018 Theos_0293 06a4d78698860c9ab667b5727457392b 112 SUPERFAMILY SSF53137 5 110 5.89E-48 T 14-10-2018 Theos_0293 06a4d78698860c9ab667b5727457392b 112 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 8 112 6.3E-39 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0293 06a4d78698860c9ab667b5727457392b 112 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 112 27.177 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_2291 0660e3174290e2683a41e32724ab02ca 67 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 41 1.2E-6 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Theos_2291 0660e3174290e2683a41e32724ab02ca 67 SUPERFAMILY SSF143120 1 42 1.83E-7 T 14-10-2018 IPR036165 YefM-like superfamily Theos_1016 822900f6e5fde8ef8da87f93f6d4acb5 363 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 363 56.734 T 14-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Theos_1016 822900f6e5fde8ef8da87f93f6d4acb5 363 PIRSF PIRSF015647 1 363 3.3E-161 T 14-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Theos_1016 822900f6e5fde8ef8da87f93f6d4acb5 363 Pfam PF01950 Fructose-1,6-bisphosphatase 2 362 5.6E-156 T 14-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Theos_1016 822900f6e5fde8ef8da87f93f6d4acb5 363 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 2 362 0.0 T 14-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Theos_1016 822900f6e5fde8ef8da87f93f6d4acb5 363 SUPERFAMILY SSF111249 2 362 1.7E-150 T 14-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Theos_1762 ed9d280fea6a2229431ba3ecdacef87a 204 Gene3D G3DSA:3.40.50.300 1 204 2.9E-70 T 14-10-2018 Theos_1762 ed9d280fea6a2229431ba3ecdacef87a 204 TIGRFAM TIGR00017 cmk: cytidylate kinase 3 201 1.6E-57 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Theos_1762 ed9d280fea6a2229431ba3ecdacef87a 204 Hamap MF_00238 Cytidylate kinase [cmk]. 3 204 26.229 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Theos_1762 ed9d280fea6a2229431ba3ecdacef87a 204 SUPERFAMILY SSF52540 4 203 1.52E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1762 ed9d280fea6a2229431ba3ecdacef87a 204 Pfam PF02224 Cytidylate kinase 5 202 8.5E-60 T 14-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Theos_1642 53b189275ee571c32be5c6a6af769c36 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 250 3.4E-111 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Theos_1642 53b189275ee571c32be5c6a6af769c36 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 250 49.219 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Theos_1642 53b189275ee571c32be5c6a6af769c36 252 Gene3D G3DSA:3.20.20.70 1 252 6.6E-108 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1642 53b189275ee571c32be5c6a6af769c36 252 SUPERFAMILY SSF51366 3 250 1.57E-82 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Theos_1642 53b189275ee571c32be5c6a6af769c36 252 Pfam PF00977 Histidine biosynthesis protein 6 233 1.6E-87 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Theos_0688 a7e15ace1e0e77cfde4b8b61df979acd 394 Pfam PF10116 Protein required for attachment to host cells 140 260 3.3E-9 T 14-10-2018 IPR019291 Host attachment protein Theos_2412 2793731b7347c299d0181f79c879a667 305 Pfam PF13614 AAA domain 54 211 1.3E-32 T 14-10-2018 IPR025669 AAA domain Theos_2412 2793731b7347c299d0181f79c879a667 305 Gene3D G3DSA:3.40.50.300 48 304 8.1E-47 T 14-10-2018 Theos_2412 2793731b7347c299d0181f79c879a667 305 SUPERFAMILY SSF52540 54 299 5.8E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0318 330f01867328f0a993d1c75ea5034f8d 442 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 225 430 1.5E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0318 330f01867328f0a993d1c75ea5034f8d 442 SUPERFAMILY SSF160964 19 183 7.59E-18 T 14-10-2018 Theos_0318 330f01867328f0a993d1c75ea5034f8d 442 SUPERFAMILY SSF161098 189 429 1.13E-55 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0318 330f01867328f0a993d1c75ea5034f8d 442 Gene3D G3DSA:1.10.3720.10 185 440 1.1E-65 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0930 dbb4caf9afd702a1daa90bdd422029c7 916 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 23 210 2.7E-19 T 14-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain Theos_0930 dbb4caf9afd702a1daa90bdd422029c7 916 SUPERFAMILY SSF52540 283 672 3.2E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0930 dbb4caf9afd702a1daa90bdd422029c7 916 Gene3D G3DSA:1.10.3210.30 3 261 7.6E-68 T 14-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily Theos_0930 dbb4caf9afd702a1daa90bdd422029c7 916 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 283 550 1.6E-30 T 14-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core Theos_1461 653565fd6f08fb638148a8a14fe0397e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 5.6E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_1461 653565fd6f08fb638148a8a14fe0397e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 71 5.6E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_1461 653565fd6f08fb638148a8a14fe0397e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 5.6E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_1461 653565fd6f08fb638148a8a14fe0397e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 5.6E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_1461 653565fd6f08fb638148a8a14fe0397e 123 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 62 80 - T 14-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 Theos_1461 653565fd6f08fb638148a8a14fe0397e 123 Gene3D G3DSA:1.10.10.10 6 122 4.8E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1461 653565fd6f08fb638148a8a14fe0397e 123 SUPERFAMILY SSF46785 26 118 1.62E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1461 653565fd6f08fb638148a8a14fe0397e 123 SMART SM00418 38 117 3.6E-30 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_1461 653565fd6f08fb638148a8a14fe0397e 123 Pfam PF01022 Bacterial regulatory protein, arsR family 45 90 6.5E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_0949 c2882866ccf4b5f8d09d4aad0f49829a 346 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 16 331 7.6E-132 T 14-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Theos_0949 c2882866ccf4b5f8d09d4aad0f49829a 346 SUPERFAMILY SSF52518 15 334 9.21E-101 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_0949 c2882866ccf4b5f8d09d4aad0f49829a 346 Pfam PF00676 Dehydrogenase E1 component 25 314 4.1E-86 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 Theos_0949 c2882866ccf4b5f8d09d4aad0f49829a 346 Gene3D G3DSA:3.40.50.970 8 339 2.6E-114 T 14-10-2018 Theos_0886 e3432f4f6bc2bdc93befc26a8a46c4c7 145 Gene3D G3DSA:3.40.50.1010 5 136 1.1E-23 T 14-10-2018 Theos_0886 e3432f4f6bc2bdc93befc26a8a46c4c7 145 SUPERFAMILY SSF88723 7 137 1.96E-15 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_0886 e3432f4f6bc2bdc93befc26a8a46c4c7 145 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 136 10.718 T 14-10-2018 IPR022907 VapC family GO:0004540 Theos_0886 e3432f4f6bc2bdc93befc26a8a46c4c7 145 Pfam PF01850 PIN domain 7 127 6.5E-13 T 14-10-2018 IPR002716 PIN domain Theos_1552 7c7ef372600796881efa3636ab4adf4f 220 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 122 209 9.9E-22 T 14-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 Theos_1552 7c7ef372600796881efa3636ab4adf4f 220 Gene3D G3DSA:3.40.50.150 1 217 1.1E-44 T 14-10-2018 Theos_1552 7c7ef372600796881efa3636ab4adf4f 220 SUPERFAMILY SSF53335 15 208 2.14E-10 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_1618 053a5851259767c615b4d9a82b2a661f 143 SMART SM00450 42 138 1.5E-16 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_1618 053a5851259767c615b4d9a82b2a661f 143 SUPERFAMILY SSF52821 31 141 4.19E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_1618 053a5851259767c615b4d9a82b2a661f 143 Pfam PF00581 Rhodanese-like domain 56 133 1.1E-13 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_1618 053a5851259767c615b4d9a82b2a661f 143 Gene3D G3DSA:3.40.250.10 42 143 5.3E-26 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_2465 60c27767d625c68620f908fe68fd4df9 296 SUPERFAMILY SSF161098 55 285 6.54E-63 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2465 60c27767d625c68620f908fe68fd4df9 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 294 8.0E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2465 60c27767d625c68620f908fe68fd4df9 296 Gene3D G3DSA:1.10.3720.10 51 295 8.3E-75 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2442 dc88c0995cdff39c982d5126b174dcf1 257 Pfam PF00005 ABC transporter 20 158 9.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2442 dc88c0995cdff39c982d5126b174dcf1 257 Gene3D G3DSA:3.40.50.300 2 210 3.9E-66 T 14-10-2018 Theos_2442 dc88c0995cdff39c982d5126b174dcf1 257 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2442 dc88c0995cdff39c982d5126b174dcf1 257 SUPERFAMILY SSF52540 4 224 1.17E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2442 dc88c0995cdff39c982d5126b174dcf1 257 SMART SM00382 28 208 7.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1054 20db6d73456590d51d0cda086aabb590 125 Pfam PF04304 Protein of unknown function (DUF454) 3 113 8.7E-32 T 14-10-2018 IPR007401 Protein of unknown function DUF454 Theos_1054 20db6d73456590d51d0cda086aabb590 125 PIRSF PIRSF016789 1 121 1.6E-27 T 14-10-2018 IPR007401 Protein of unknown function DUF454 Theos_1121 89b821340a52e7eef50024c1d14e3ef1 443 Pfam PF00905 Penicillin binding protein transpeptidase domain 138 425 1.2E-47 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Theos_1121 89b821340a52e7eef50024c1d14e3ef1 443 Gene3D G3DSA:3.30.450.330 114 431 2.4E-73 T 14-10-2018 Theos_1121 89b821340a52e7eef50024c1d14e3ef1 443 Gene3D G3DSA:3.90.1310.10 43 113 1.6E-6 T 14-10-2018 Theos_1121 89b821340a52e7eef50024c1d14e3ef1 443 SUPERFAMILY SSF56601 113 438 2.73E-65 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Theos_1121 89b821340a52e7eef50024c1d14e3ef1 443 Gene3D G3DSA:3.40.710.10 174 350 2.4E-73 T 14-10-2018 Theos_1427 63fe33cac8250c2af51e33c23bd0956c 371 Gene3D G3DSA:1.10.260.150 33 267 3.9E-59 T 14-10-2018 Theos_1427 63fe33cac8250c2af51e33c23bd0956c 371 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 61 208 2.8E-38 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain Theos_1427 63fe33cac8250c2af51e33c23bd0956c 371 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 62 207 2.1E-37 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain Theos_1747 8a7a94691ad1c1a4eda5233630dccf6f 508 Gene3D G3DSA:3.40.50.300 1 207 3.1E-85 T 14-10-2018 Theos_1747 8a7a94691ad1c1a4eda5233630dccf6f 508 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Theos_1747 8a7a94691ad1c1a4eda5233630dccf6f 508 SMART SM00487 20 214 5.7E-64 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_1747 8a7a94691ad1c1a4eda5233630dccf6f 508 SMART SM00490 251 332 5.0E-36 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1747 8a7a94691ad1c1a4eda5233630dccf6f 508 Pfam PF00270 DEAD/DEAH box helicase 25 191 1.1E-46 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Theos_1747 8a7a94691ad1c1a4eda5233630dccf6f 508 Pfam PF00271 Helicase conserved C-terminal domain 227 332 6.8E-30 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1747 8a7a94691ad1c1a4eda5233630dccf6f 508 Gene3D G3DSA:3.30.70.1800 366 493 3.2E-53 T 14-10-2018 Theos_1747 8a7a94691ad1c1a4eda5233630dccf6f 508 SUPERFAMILY SSF52540 72 353 4.12E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1747 8a7a94691ad1c1a4eda5233630dccf6f 508 Gene3D G3DSA:3.40.50.300 222 364 2.4E-47 T 14-10-2018 Theos_0122 2cfea3aab9aa339f61edeeb380f220c3 282 Gene3D G3DSA:1.10.3720.10 50 281 2.8E-57 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0122 2cfea3aab9aa339f61edeeb380f220c3 282 SUPERFAMILY SSF161098 52 270 3.53E-47 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0122 2cfea3aab9aa339f61edeeb380f220c3 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 272 1.9E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1184 45daddd8e6b1b1c355730e7beea6aeb5 655 Gene3D G3DSA:3.10.310.30 307 422 6.5E-35 T 14-10-2018 Theos_1184 45daddd8e6b1b1c355730e7beea6aeb5 655 Pfam PF02272 DHHA1 domain 305 415 3.1E-10 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Theos_1184 45daddd8e6b1b1c355730e7beea6aeb5 655 Gene3D G3DSA:1.20.120.1040 536 655 1.7E-37 T 14-10-2018 Theos_1184 45daddd8e6b1b1c355730e7beea6aeb5 655 Gene3D G3DSA:3.90.1640.30 47 306 3.2E-93 T 14-10-2018 Theos_1184 45daddd8e6b1b1c355730e7beea6aeb5 655 SUPERFAMILY SSF64182 53 420 3.27E-105 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily Theos_1184 45daddd8e6b1b1c355730e7beea6aeb5 655 Pfam PF01368 DHH family 74 164 2.5E-9 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 Gene3D G3DSA:1.10.10.10 393 491 4.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 SUPERFAMILY SSF48452 493 593 4.43E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 Pfam PF03704 Bacterial transcriptional activator domain 496 592 7.1E-9 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 SMART SM01043 496 597 1.3E-7 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 Gene3D G3DSA:1.25.40.10 495 596 3.0E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 Pfam PF13185 GAF domain 128 252 1.2E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 SMART SM00065 117 264 0.0035 T 14-10-2018 IPR003018 GAF domain GO:0005515 Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 Gene3D G3DSA:3.30.450.40 98 255 1.0E-17 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 SUPERFAMILY SSF46894 401 477 1.3E-5 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Theos_1043 da04bb8f1d8147ece33f23db386bc09e 597 SUPERFAMILY SSF55781 104 255 1.29E-16 T 14-10-2018 Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.1E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.1E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.1E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.1E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.1E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 7.1E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 Pfam PF00106 short chain dehydrogenase 5 190 4.8E-55 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 SUPERFAMILY SSF51735 2 224 1.68E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PIRSF PIRSF000126 2 233 9.6E-53 T 14-10-2018 Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.4E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.4E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.4E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1289 d81e5996aca46b45868a22160324c9ad 240 Gene3D G3DSA:3.40.50.720 1 230 3.1E-72 T 14-10-2018 Theos_1289 d81e5996aca46b45868a22160324c9ad 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 189 1.7E-4 T 14-10-2018 Theos_0193 fe3cc319ae7430dd04f6fe761d1fb217 386 Gene3D G3DSA:3.40.50.12300 77 386 3.0E-105 T 14-10-2018 IPR038136 Gluconeogenesis factor superfamily Theos_0193 fe3cc319ae7430dd04f6fe761d1fb217 386 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 82 385 1.2E-96 T 14-10-2018 IPR010119 Gluconeogenesis factor Theos_0193 fe3cc319ae7430dd04f6fe761d1fb217 386 Pfam PF01933 Uncharacterised protein family UPF0052 82 364 7.4E-86 T 14-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 Theos_0193 fe3cc319ae7430dd04f6fe761d1fb217 386 SUPERFAMILY SSF142338 79 383 2.88E-85 T 14-10-2018 Theos_0193 fe3cc319ae7430dd04f6fe761d1fb217 386 Hamap MF_00973 Gluconeogenesis factor. 78 386 32.232 T 14-10-2018 IPR010119 Gluconeogenesis factor Theos_0818 0df9df58962aeb96d542ac10b4466944 188 SUPERFAMILY SSF160527 78 188 7.45E-13 T 14-10-2018 Theos_0818 0df9df58962aeb96d542ac10b4466944 188 Pfam PF01991 ATP synthase (E/31 kDa) subunit 9 123 5.4E-9 T 14-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0818 0df9df58962aeb96d542ac10b4466944 188 Gene3D G3DSA:3.30.2320.30 98 188 6.2E-21 T 14-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0818 0df9df58962aeb96d542ac10b4466944 188 Gene3D G3DSA:1.20.5.620 2 97 2.1E-24 T 14-10-2018 Theos_0818 0df9df58962aeb96d542ac10b4466944 188 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 188 11.055 T 14-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0599 6732becd2b82548944fe4190c243bc6a 210 Gene3D G3DSA:3.40.30.10 27 209 1.9E-50 T 14-10-2018 Theos_0599 6732becd2b82548944fe4190c243bc6a 210 SUPERFAMILY SSF52833 36 204 3.35E-42 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0599 6732becd2b82548944fe4190c243bc6a 210 Pfam PF13462 Thioredoxin 37 205 4.1E-38 T 14-10-2018 IPR012336 Thioredoxin-like fold Theos_0685 01f8065eebc57d8f2b47066e1f049b52 78 Pfam PF13591 MerR HTH family regulatory protein 11 77 1.7E-11 T 14-10-2018 Theos_0685 01f8065eebc57d8f2b47066e1f049b52 78 Gene3D G3DSA:1.10.1660.10 6 78 6.6E-15 T 14-10-2018 Theos_0685 01f8065eebc57d8f2b47066e1f049b52 78 SUPERFAMILY SSF46955 11 54 1.24E-5 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_1086 dafc45f253faa6a300152364ee3ae095 284 Pfam PF01497 Periplasmic binding protein 39 253 1.1E-30 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain Theos_1086 dafc45f253faa6a300152364ee3ae095 284 Gene3D G3DSA:3.40.50.1980 21 150 2.2E-35 T 14-10-2018 Theos_1086 dafc45f253faa6a300152364ee3ae095 284 SUPERFAMILY SSF53807 15 282 9.03E-66 T 14-10-2018 Theos_1086 dafc45f253faa6a300152364ee3ae095 284 Gene3D G3DSA:3.40.50.1980 154 283 1.0E-29 T 14-10-2018 Theos_0345 82890a68997b8698dc3b21c0e6db5822 105 PIRSF PIRSF004555 1 105 2.7E-27 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Theos_0345 82890a68997b8698dc3b21c0e6db5822 105 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 94 6.1E-17 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Theos_0345 82890a68997b8698dc3b21c0e6db5822 105 Pfam PF02575 YbaB/EbfC DNA-binding family 8 96 6.4E-23 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Theos_0345 82890a68997b8698dc3b21c0e6db5822 105 Gene3D G3DSA:3.30.1310.10 1 103 9.3E-25 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily Theos_0345 82890a68997b8698dc3b21c0e6db5822 105 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 96 18.774 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Theos_0345 82890a68997b8698dc3b21c0e6db5822 105 SUPERFAMILY SSF82607 3 96 4.05E-21 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily Theos_2445 8ce97ebc6de7d5ce8f7255bdeb8e125b 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 265 1.7E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2445 8ce97ebc6de7d5ce8f7255bdeb8e125b 267 Gene3D G3DSA:1.10.3720.10 55 266 1.8E-21 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2445 8ce97ebc6de7d5ce8f7255bdeb8e125b 267 SUPERFAMILY SSF161098 60 243 3.79E-23 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0746 5c709d98c14bff84792d72426ee45e35 438 SUPERFAMILY SSF53383 1 437 4.95E-114 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0746 5c709d98c14bff84792d72426ee45e35 438 Gene3D G3DSA:3.90.1150.10 68 433 1.5E-152 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0746 5c709d98c14bff84792d72426ee45e35 438 PIRSF PIRSF006815 1 437 1.9E-152 T 14-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 Theos_0746 5c709d98c14bff84792d72426ee45e35 438 Gene3D G3DSA:3.40.640.10 79 340 1.5E-152 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0746 5c709d98c14bff84792d72426ee45e35 438 Pfam PF02347 Glycine cleavage system P-protein 3 377 2.1E-116 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Theos_0746 5c709d98c14bff84792d72426ee45e35 438 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 1 436 42.326 T 14-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 Theos_0291 7f53262ac7941af8517c9c05a9a4cf05 138 ProSitePatterns PS00053 Ribosomal protein S8 signature. 108 125 - T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0291 7f53262ac7941af8517c9c05a9a4cf05 138 SUPERFAMILY SSF56047 1 138 2.62E-48 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0291 7f53262ac7941af8517c9c05a9a4cf05 138 Gene3D G3DSA:3.30.1490.10 81 138 1.1E-28 T 14-10-2018 Theos_0291 7f53262ac7941af8517c9c05a9a4cf05 138 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 1 138 32.884 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0291 7f53262ac7941af8517c9c05a9a4cf05 138 Pfam PF00410 Ribosomal protein S8 4 138 1.2E-49 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0291 7f53262ac7941af8517c9c05a9a4cf05 138 Gene3D G3DSA:3.30.1370.30 3 80 5.6E-35 T 14-10-2018 Theos_1069 070afe73b485a6804530ccf219373777 307 SMART SM00327 77 268 5.6E-16 T 14-10-2018 IPR002035 von Willebrand factor, type A Theos_1069 070afe73b485a6804530ccf219373777 307 SUPERFAMILY SSF53300 79 255 6.12E-25 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_1069 070afe73b485a6804530ccf219373777 307 Gene3D G3DSA:3.40.50.410 74 261 4.3E-34 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_1069 070afe73b485a6804530ccf219373777 307 Pfam PF13519 von Willebrand factor type A domain 80 193 3.3E-20 T 14-10-2018 IPR002035 von Willebrand factor, type A Theos_0498 001021d967e9a39d8ca3de7e6d2d51c8 226 Hamap MF_00801 Endonuclease V [nfi]. 11 225 31.854 T 14-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 Theos_0498 001021d967e9a39d8ca3de7e6d2d51c8 226 Gene3D G3DSA:3.30.2170.10 5 226 7.1E-60 T 14-10-2018 Theos_0498 001021d967e9a39d8ca3de7e6d2d51c8 226 Pfam PF04493 Endonuclease V 22 215 2.1E-56 T 14-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 Theos_0981 8bc6b4504b20d4123a786d8fbc73ed03 140 Gene3D G3DSA:3.10.129.10 1 140 1.6E-37 T 14-10-2018 Theos_0981 8bc6b4504b20d4123a786d8fbc73ed03 140 PIRSF PIRSF014972 1 136 3.4E-38 T 14-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase Theos_0981 8bc6b4504b20d4123a786d8fbc73ed03 140 SUPERFAMILY SSF54637 2 135 3.82E-37 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_1386 448522b53ad889313db296c04f8049ba 259 Gene3D G3DSA:3.40.50.300 3 252 8.5E-52 T 14-10-2018 Theos_1386 448522b53ad889313db296c04f8049ba 259 SMART SM00382 28 218 5.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1386 448522b53ad889313db296c04f8049ba 259 SUPERFAMILY SSF52540 3 238 4.35E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1386 448522b53ad889313db296c04f8049ba 259 Pfam PF00005 ABC transporter 19 168 4.8E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1386 448522b53ad889313db296c04f8049ba 259 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1670 285228063e8f58f1497f1f896c7d1e8f 141 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 13 139 28.566 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Theos_1670 285228063e8f58f1497f1f896c7d1e8f 141 SUPERFAMILY SSF52161 6 140 3.14E-55 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Theos_1670 285228063e8f58f1497f1f896c7d1e8f 141 Pfam PF00572 Ribosomal protein L13 12 135 7.1E-55 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Theos_1670 285228063e8f58f1497f1f896c7d1e8f 141 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 139 5.0E-59 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1670 285228063e8f58f1497f1f896c7d1e8f 141 ProSitePatterns PS00783 Ribosomal protein L13 signature. 103 125 - T 14-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 Theos_1670 285228063e8f58f1497f1f896c7d1e8f 141 Gene3D G3DSA:3.90.1180.10 1 140 3.1E-63 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Theos_1670 285228063e8f58f1497f1f896c7d1e8f 141 PIRSF PIRSF002181 1 141 2.1E-52 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Theos_0565 19c83ded984e1a2393e8c95dd0077130 207 Pfam PF00583 Acetyltransferase (GNAT) family 49 179 1.6E-14 T 14-10-2018 IPR000182 GNAT domain Theos_0565 19c83ded984e1a2393e8c95dd0077130 207 SUPERFAMILY SSF55729 1 186 3.08E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_0565 19c83ded984e1a2393e8c95dd0077130 207 Gene3D G3DSA:3.40.630.30 2 194 9.7E-37 T 14-10-2018 Theos_2407 9a884158fd80a42cea098b7d3bd9ee25 156 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 151 8.9E-28 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ Theos_1011 1ae711419d6838ff52b6a97a7c5fada4 307 Gene3D G3DSA:3.40.50.10800 172 262 9.2E-113 T 14-10-2018 Theos_1011 1ae711419d6838ff52b6a97a7c5fada4 307 SUPERFAMILY SSF142754 6 305 7.45E-106 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Theos_1011 1ae711419d6838ff52b6a97a7c5fada4 307 Gene3D G3DSA:3.40.50.10800 8 287 9.2E-113 T 14-10-2018 Theos_1011 1ae711419d6838ff52b6a97a7c5fada4 307 Gene3D G3DSA:3.40.50.10800 88 304 9.2E-113 T 14-10-2018 Theos_1011 1ae711419d6838ff52b6a97a7c5fada4 307 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 2 306 7.2E-98 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Theos_1011 1ae711419d6838ff52b6a97a7c5fada4 307 Pfam PF02445 Quinolinate synthetase A protein 9 304 3.7E-111 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Theos_1011 1ae711419d6838ff52b6a97a7c5fada4 307 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 306 42.27 T 14-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Theos_0103 53d9ab905f66e8e85d496db9a62223d8 387 Gene3D G3DSA:3.40.190.10 19 385 1.4E-41 T 14-10-2018 Theos_0103 53d9ab905f66e8e85d496db9a62223d8 387 Pfam PF13416 Bacterial extracellular solute-binding protein 42 322 1.7E-18 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_0103 53d9ab905f66e8e85d496db9a62223d8 387 SUPERFAMILY SSF53850 22 381 1.41E-42 T 14-10-2018 Theos_0447 1e230950ccfdbad01bc4e9efc7e1f1c8 253 Hamap MF_01274 Type III pantothenate kinase [coaX]. 2 253 31.811 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Theos_0447 1e230950ccfdbad01bc4e9efc7e1f1c8 253 SUPERFAMILY SSF53067 124 250 1.24E-34 T 14-10-2018 Theos_0447 1e230950ccfdbad01bc4e9efc7e1f1c8 253 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 247 9.5E-60 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Theos_0447 1e230950ccfdbad01bc4e9efc7e1f1c8 253 Gene3D G3DSA:3.30.420.40 4 244 5.9E-77 T 14-10-2018 Theos_0447 1e230950ccfdbad01bc4e9efc7e1f1c8 253 Gene3D G3DSA:3.30.420.490 124 237 5.9E-77 T 14-10-2018 Theos_0447 1e230950ccfdbad01bc4e9efc7e1f1c8 253 Pfam PF03309 Type III pantothenate kinase 3 206 8.1E-61 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Theos_0447 1e230950ccfdbad01bc4e9efc7e1f1c8 253 SUPERFAMILY SSF53067 2 117 1.29E-27 T 14-10-2018 Theos_2545 10121201dc0cc1b87aaee78c97a80d3c 637 Pfam PF00082 Subtilase family 201 437 5.6E-32 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Theos_2545 10121201dc0cc1b87aaee78c97a80d3c 637 PRINTS PR00723 Subtilisin serine protease family (S8) signature 201 220 1.2E-14 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_2545 10121201dc0cc1b87aaee78c97a80d3c 637 PRINTS PR00723 Subtilisin serine protease family (S8) signature 420 436 1.2E-14 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_2545 10121201dc0cc1b87aaee78c97a80d3c 637 PRINTS PR00723 Subtilisin serine protease family (S8) signature 245 258 1.2E-14 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_2545 10121201dc0cc1b87aaee78c97a80d3c 637 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 421 431 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site Theos_2545 10121201dc0cc1b87aaee78c97a80d3c 637 SUPERFAMILY SSF52743 183 457 4.32E-62 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_2545 10121201dc0cc1b87aaee78c97a80d3c 637 Gene3D G3DSA:3.40.50.200 177 472 1.9E-68 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_1151 975d434dc6928b15500440069cdc9e0a 342 Gene3D G3DSA:3.90.550.10 35 245 1.1E-27 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1151 975d434dc6928b15500440069cdc9e0a 342 SUPERFAMILY SSF53448 28 274 3.3E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1151 975d434dc6928b15500440069cdc9e0a 342 Pfam PF00535 Glycosyl transferase family 2 42 151 1.2E-16 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Theos_1968 231735ca56f4d2d120a9f3436b82431a 242 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 16 237 2.4E-63 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase Theos_1968 231735ca56f4d2d120a9f3436b82431a 242 Gene3D G3DSA:3.60.140.10 4 240 4.1E-74 T 14-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily Theos_1968 231735ca56f4d2d120a9f3436b82431a 242 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 22 239 1.6E-43 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase Theos_1968 231735ca56f4d2d120a9f3436b82431a 242 SUPERFAMILY SSF64438 8 239 2.2E-71 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic Theos_1587 97b1b9bd2dcb425d3059bc63dcc44491 247 Pfam PF00902 Sec-independent protein translocase protein (TatC) 8 222 2.7E-63 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Theos_1587 97b1b9bd2dcb425d3059bc63dcc44491 247 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 6 227 3.1E-61 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Theos_1587 97b1b9bd2dcb425d3059bc63dcc44491 247 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 239 15.363 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Theos_1587 97b1b9bd2dcb425d3059bc63dcc44491 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 5 32 6.6E-37 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Theos_1587 97b1b9bd2dcb425d3059bc63dcc44491 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 129 6.6E-37 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Theos_1587 97b1b9bd2dcb425d3059bc63dcc44491 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 6.6E-37 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Theos_1587 97b1b9bd2dcb425d3059bc63dcc44491 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 85 103 6.6E-37 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Theos_1165 24f0076269156c5d4cfd8810d28c8e68 195 Gene3D G3DSA:2.40.30.20 1 86 6.7E-23 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_1165 24f0076269156c5d4cfd8810d28c8e68 195 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 192 5.4E-57 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1165 24f0076269156c5d4cfd8810d28c8e68 195 Pfam PF00677 Lumazine binding domain 3 84 6.1E-17 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1165 24f0076269156c5d4cfd8810d28c8e68 195 Pfam PF00677 Lumazine binding domain 97 181 8.0E-21 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1165 24f0076269156c5d4cfd8810d28c8e68 195 PIRSF PIRSF000498 1 195 8.6E-65 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Theos_1165 24f0076269156c5d4cfd8810d28c8e68 195 SUPERFAMILY SSF63380 90 192 1.87E-30 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Theos_1165 24f0076269156c5d4cfd8810d28c8e68 195 Gene3D G3DSA:2.40.30.20 99 195 1.9E-29 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Theos_1165 24f0076269156c5d4cfd8810d28c8e68 195 SUPERFAMILY SSF63380 1 90 1.53E-20 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Theos_1428 987c0872b7aa1e2b97a8e888c04e4fbc 441 SUPERFAMILY SSF52743 148 434 1.57E-69 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_1428 987c0872b7aa1e2b97a8e888c04e4fbc 441 PRINTS PR00723 Subtilisin serine protease family (S8) signature 163 182 9.5E-8 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_1428 987c0872b7aa1e2b97a8e888c04e4fbc 441 PRINTS PR00723 Subtilisin serine protease family (S8) signature 213 226 9.5E-8 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_1428 987c0872b7aa1e2b97a8e888c04e4fbc 441 PRINTS PR00723 Subtilisin serine protease family (S8) signature 369 385 9.5E-8 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Theos_1428 987c0872b7aa1e2b97a8e888c04e4fbc 441 Gene3D G3DSA:3.40.50.200 133 437 1.0E-74 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Theos_1428 987c0872b7aa1e2b97a8e888c04e4fbc 441 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 370 380 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site Theos_1428 987c0872b7aa1e2b97a8e888c04e4fbc 441 Pfam PF00082 Subtilase family 164 425 1.2E-39 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Theos_1501 0fe395f4259ed3c04c88c64675b9623d 382 Gene3D G3DSA:1.20.1250.20 202 379 1.6E-23 T 14-10-2018 Theos_1501 0fe395f4259ed3c04c88c64675b9623d 382 SUPERFAMILY SSF103473 6 379 6.54E-62 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1501 0fe395f4259ed3c04c88c64675b9623d 382 Pfam PF07690 Major Facilitator Superfamily 211 376 3.2E-20 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_1501 0fe395f4259ed3c04c88c64675b9623d 382 Pfam PF07690 Major Facilitator Superfamily 12 191 8.8E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_1501 0fe395f4259ed3c04c88c64675b9623d 382 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 77 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Theos_1501 0fe395f4259ed3c04c88c64675b9623d 382 Gene3D G3DSA:1.20.1250.20 4 187 3.4E-28 T 14-10-2018 Theos_0019 0927e0932598149486457b15d150bcf1 197 TIGRFAM TIGR00444 mazG: MazG family protein 10 149 5.8E-48 T 14-10-2018 IPR011551 NTP pyrophosphohydrolase MazG Theos_0019 0927e0932598149486457b15d150bcf1 197 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 26 99 1.3E-25 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Theos_0019 0927e0932598149486457b15d150bcf1 197 Gene3D G3DSA:1.10.287.1080 1 123 2.0E-44 T 14-10-2018 Theos_0019 0927e0932598149486457b15d150bcf1 197 SUPERFAMILY SSF101386 3 104 1.8E-23 T 14-10-2018 Theos_0034 64655cd9f10ece72ebae947b2a8445f3 605 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 325 602 1.9E-98 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 Theos_0034 64655cd9f10ece72ebae947b2a8445f3 605 Pfam PF02628 Cytochrome oxidase assembly protein 10 291 8.0E-31 T 14-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 Theos_0034 64655cd9f10ece72ebae947b2a8445f3 605 Pfam PF01040 UbiA prenyltransferase family 339 585 3.9E-62 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 Theos_0034 64655cd9f10ece72ebae947b2a8445f3 605 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 323 604 19.449 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 Theos_0034 64655cd9f10ece72ebae947b2a8445f3 605 Gene3D G3DSA:1.10.357.140 334 487 2.4E-20 T 14-10-2018 Theos_1934 866af36d7409d5ef9d69a6c62c7a0c68 54 TIGRFAM TIGR01206 lysW: lysine biosynthesis protein LysW 1 54 2.6E-33 T 14-10-2018 IPR005906 Lysine biosynthesis protein LysW Theos_1934 866af36d7409d5ef9d69a6c62c7a0c68 54 Gene3D G3DSA:2.20.28.160 1 54 1.9E-26 T 14-10-2018 Theos_1934 866af36d7409d5ef9d69a6c62c7a0c68 54 SUPERFAMILY SSF161187 2 35 6.02E-5 T 14-10-2018 Theos_1934 866af36d7409d5ef9d69a6c62c7a0c68 54 Pfam PF08271 TFIIB zinc-binding 4 40 2.8E-10 T 14-10-2018 IPR013137 Zinc finger, TFIIB-type Theos_2488 4be2c34eba821b017651ead9f060b02c 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 10 26 4.7E-9 T 14-10-2018 Theos_2488 4be2c34eba821b017651ead9f060b02c 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 38 52 4.7E-9 T 14-10-2018 Theos_2488 4be2c34eba821b017651ead9f060b02c 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 93 105 4.7E-9 T 14-10-2018 Theos_2488 4be2c34eba821b017651ead9f060b02c 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 110 134 4.7E-9 T 14-10-2018 Theos_2488 4be2c34eba821b017651ead9f060b02c 328 SUPERFAMILY SSF53335 12 158 6.12E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_2488 4be2c34eba821b017651ead9f060b02c 328 Gene3D G3DSA:3.40.50.150 8 145 6.3E-11 T 14-10-2018 Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 16 292 1.8E-76 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 15 77 1.1E-8 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 Gene3D G3DSA:3.40.50.620 3 173 1.6E-50 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 Gene3D G3DSA:2.40.30.30 175 293 5.1E-40 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 SUPERFAMILY SSF82114 160 293 1.53E-41 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 SUPERFAMILY SSF52374 14 171 2.2E-29 T 14-10-2018 Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 SMART SM00904 170 293 1.5E-55 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 Pfam PF06574 FAD synthetase 13 153 7.2E-39 T 14-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 Pfam PF01687 Riboflavin kinase 171 292 4.0E-35 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 Theos_0755 2db20d3e1bf67c90703d508ea7134c69 294 PIRSF PIRSF004491 2 293 3.5E-95 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 Theos_1807 9931886e898ebf3c874e355ee9be76d0 105 SUPERFAMILY SSF81301 8 103 7.25E-18 T 14-10-2018 Theos_1807 9931886e898ebf3c874e355ee9be76d0 105 Gene3D G3DSA:3.30.460.10 3 102 6.3E-17 T 14-10-2018 Theos_1807 9931886e898ebf3c874e355ee9be76d0 105 Pfam PF01909 Nucleotidyltransferase domain 11 89 8.9E-12 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Theos_1879 548f09caef6bfe16577805c9688e366b 123 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 122 1.1E-26 T 14-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like Theos_1879 548f09caef6bfe16577805c9688e366b 123 Gene3D G3DSA:3.10.490.10 1 123 7.8E-27 T 14-10-2018 Theos_1879 548f09caef6bfe16577805c9688e366b 123 SUPERFAMILY SSF110857 3 122 8.37E-28 T 14-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily Theos_1792 541ab6774d37ed7117224e6e8438f840 291 Gene3D G3DSA:1.10.3210.10 53 205 4.8E-7 T 14-10-2018 Theos_1792 541ab6774d37ed7117224e6e8438f840 291 SUPERFAMILY SSF109604 67 194 1.99E-8 T 14-10-2018 Theos_1852 5c5e0c50b1287b5838bc873aadfadf59 304 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 233 246 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Theos_1852 5c5e0c50b1287b5838bc873aadfadf59 304 Pfam PF00294 pfkB family carbohydrate kinase 2 290 4.6E-34 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB Theos_1852 5c5e0c50b1287b5838bc873aadfadf59 304 Gene3D G3DSA:3.40.1190.20 1 292 6.5E-60 T 14-10-2018 IPR029056 Ribokinase-like Theos_1852 5c5e0c50b1287b5838bc873aadfadf59 304 SUPERFAMILY SSF53613 4 288 1.14E-52 T 14-10-2018 IPR029056 Ribokinase-like Theos_1334 f0e336e566ad7dd02d2a2733c2db1b23 336 Pfam PF02163 Peptidase family M50 6 321 1.6E-51 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Theos_1334 f0e336e566ad7dd02d2a2733c2db1b23 336 SUPERFAMILY SSF50156 89 182 1.84E-16 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Theos_1334 f0e336e566ad7dd02d2a2733c2db1b23 336 Pfam PF13180 PDZ domain 114 181 3.3E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_1334 f0e336e566ad7dd02d2a2733c2db1b23 336 SMART SM00228 105 174 5.6E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Theos_1334 f0e336e566ad7dd02d2a2733c2db1b23 336 Gene3D G3DSA:2.30.42.10 105 185 8.2E-15 T 14-10-2018 Theos_2374 a52adfbfe740bc6db8f101bb898aeab5 206 SUPERFAMILY SSF47240 39 166 2.71E-16 T 14-10-2018 IPR009078 Ferritin-like superfamily Theos_2374 a52adfbfe740bc6db8f101bb898aeab5 206 Pfam PF13668 Ferritin-like domain 39 166 9.7E-31 T 14-10-2018 Theos_2374 a52adfbfe740bc6db8f101bb898aeab5 206 Gene3D G3DSA:1.20.1260.10 39 170 8.9E-6 T 14-10-2018 IPR012347 Ferritin-like Theos_2303 3f7c9ca10af3c86cb5e129d331fad5eb 240 SUPERFAMILY SSF53790 1 227 8.51E-58 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Theos_2303 3f7c9ca10af3c86cb5e129d331fad5eb 240 Gene3D G3DSA:3.40.1010.10 1 114 2.9E-43 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Theos_2303 3f7c9ca10af3c86cb5e129d331fad5eb 240 Gene3D G3DSA:3.30.950.10 115 239 4.3E-35 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Theos_2303 3f7c9ca10af3c86cb5e129d331fad5eb 240 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Theos_2303 3f7c9ca10af3c86cb5e129d331fad5eb 240 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 205 3.6E-44 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Theos_2303 3f7c9ca10af3c86cb5e129d331fad5eb 240 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 224 2.5E-71 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Theos_2303 3f7c9ca10af3c86cb5e129d331fad5eb 240 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 79 112 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Theos_0273 4bee6520477a3ae84a969d0b84086eb4 156 SUPERFAMILY SSF47973 3 152 1.83E-58 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Theos_0273 4bee6520477a3ae84a969d0b84086eb4 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 3.7E-64 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Theos_0273 4bee6520477a3ae84a969d0b84086eb4 156 Gene3D G3DSA:1.10.455.10 6 156 1.2E-64 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Theos_0273 4bee6520477a3ae84a969d0b84086eb4 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0273 4bee6520477a3ae84a969d0b84086eb4 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 9.4E-63 T 14-10-2018 IPR023798 Ribosomal protein S7 domain Theos_0273 4bee6520477a3ae84a969d0b84086eb4 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.162 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Theos_0273 4bee6520477a3ae84a969d0b84086eb4 156 PIRSF PIRSF002122 2 156 2.7E-62 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 Theos_1018 673ea88dc8cb631915e646f30446e678 923 SMART SM00490 495 578 7.7E-19 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1018 673ea88dc8cb631915e646f30446e678 923 SUPERFAMILY SSF52540 93 293 2.62E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1018 673ea88dc8cb631915e646f30446e678 923 SMART SM00487 98 294 5.8E-17 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_1018 673ea88dc8cb631915e646f30446e678 923 Gene3D G3DSA:3.40.50.300 426 609 9.6E-37 T 14-10-2018 Theos_1018 673ea88dc8cb631915e646f30446e678 923 Gene3D G3DSA:3.40.50.10810 98 356 8.4E-62 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Theos_1018 673ea88dc8cb631915e646f30446e678 923 Pfam PF00176 SNF2 family N-terminal domain 104 285 5.0E-8 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Theos_1018 673ea88dc8cb631915e646f30446e678 923 Pfam PF00271 Helicase conserved C-terminal domain 465 578 5.3E-18 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_1018 673ea88dc8cb631915e646f30446e678 923 SUPERFAMILY SSF52540 222 616 2.28E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2448 dc6c6cb80820124acff3e8bea2fbf498 385 Gene3D G3DSA:3.40.630.10 19 372 7.5E-91 T 14-10-2018 Theos_2448 dc6c6cb80820124acff3e8bea2fbf498 385 SUPERFAMILY SSF55031 186 287 6.88E-15 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Theos_2448 dc6c6cb80820124acff3e8bea2fbf498 385 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 112 150 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Theos_2448 dc6c6cb80820124acff3e8bea2fbf498 385 Pfam PF01546 Peptidase family M20/M25/M40 78 380 6.8E-38 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 Theos_2448 dc6c6cb80820124acff3e8bea2fbf498 385 Gene3D G3DSA:3.30.70.360 186 300 7.5E-91 T 14-10-2018 Theos_2448 dc6c6cb80820124acff3e8bea2fbf498 385 SUPERFAMILY SSF53187 6 381 5.14E-62 T 14-10-2018 Theos_2448 dc6c6cb80820124acff3e8bea2fbf498 385 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 18 374 4.8E-65 T 14-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase Theos_2448 dc6c6cb80820124acff3e8bea2fbf498 385 Pfam PF07687 Peptidase dimerisation domain 184 287 2.6E-14 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain Theos_1715 91c2d417ad08c770720c958c0d9406fd 197 Pfam PF01712 Deoxynucleoside kinase 3 192 1.8E-35 T 14-10-2018 IPR031314 Deoxynucleoside kinase domain Theos_1715 91c2d417ad08c770720c958c0d9406fd 197 Gene3D G3DSA:3.40.50.300 2 186 2.4E-44 T 14-10-2018 Theos_1715 91c2d417ad08c770720c958c0d9406fd 197 PIRSF PIRSF000705 1 196 2.7E-48 T 14-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 Theos_1715 91c2d417ad08c770720c958c0d9406fd 197 SUPERFAMILY SSF52540 3 190 6.44E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1757 e17294631a5fd74ea53f475719c8275c 324 SUPERFAMILY SSF64182 26 319 2.09E-53 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily Theos_1757 e17294631a5fd74ea53f475719c8275c 324 Gene3D G3DSA:3.90.1640.10 11 200 2.8E-48 T 14-10-2018 Theos_1757 e17294631a5fd74ea53f475719c8275c 324 Pfam PF01368 DHH family 27 161 5.6E-10 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Theos_1757 e17294631a5fd74ea53f475719c8275c 324 Pfam PF02272 DHHA1 domain 194 314 1.8E-10 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Theos_1757 e17294631a5fd74ea53f475719c8275c 324 Gene3D G3DSA:3.10.310.30 206 320 1.1E-18 T 14-10-2018 Theos_1809 1a60d70aacae06fb6a4dcc9ee764705a 370 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 3 336 5.9E-72 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 Theos_1809 1a60d70aacae06fb6a4dcc9ee764705a 370 Gene3D G3DSA:3.80.30.20 2 269 6.2E-78 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Theos_1809 1a60d70aacae06fb6a4dcc9ee764705a 370 SUPERFAMILY SSF102114 3 361 1.83E-84 T 14-10-2018 Theos_1809 1a60d70aacae06fb6a4dcc9ee764705a 370 Pfam PF04055 Radical SAM superfamily 6 162 1.5E-22 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_1809 1a60d70aacae06fb6a4dcc9ee764705a 370 SMART SM00729 1 212 1.1E-44 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_1809 1a60d70aacae06fb6a4dcc9ee764705a 370 Pfam PF06969 HemN C-terminal domain 286 349 9.0E-16 T 14-10-2018 IPR010723 HemN, C-terminal Theos_0134 1f7185e4cde228e968a8ed684abf9227 254 Gene3D G3DSA:1.10.12.10 197 254 5.5E-25 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Theos_0134 1f7185e4cde228e968a8ed684abf9227 254 SUPERFAMILY SSF52096 5 254 9.39E-83 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_0134 1f7185e4cde228e968a8ed684abf9227 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 253 3.7E-64 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Theos_0134 1f7185e4cde228e968a8ed684abf9227 254 Gene3D G3DSA:3.90.226.10 1 196 4.8E-75 T 14-10-2018 Theos_0163 b268822b475e9b7125277511ef843ac2 395 Gene3D G3DSA:3.40.50.10540 4 386 5.0E-140 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Theos_0163 b268822b475e9b7125277511ef843ac2 395 Pfam PF02515 CoA-transferase family III 4 368 1.3E-134 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 Theos_0163 b268822b475e9b7125277511ef843ac2 395 Gene3D G3DSA:3.30.1540.10 230 319 5.0E-140 T 14-10-2018 Theos_0163 b268822b475e9b7125277511ef843ac2 395 SUPERFAMILY SSF89796 4 392 1.44E-145 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Theos_0670 b45ba09067c413d0a9da38ba6479c06b 80 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 77 3.9E-35 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Theos_0670 b45ba09067c413d0a9da38ba6479c06b 80 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 23.225 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Theos_0670 b45ba09067c413d0a9da38ba6479c06b 80 ProSitePatterns PS00012 Phosphopantetheine attachment site. 34 49 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site Theos_0670 b45ba09067c413d0a9da38ba6479c06b 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 43 79 6.0E-13 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Theos_0670 b45ba09067c413d0a9da38ba6479c06b 80 Pfam PF00550 Phosphopantetheine attachment site 8 75 8.5E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain Theos_0670 b45ba09067c413d0a9da38ba6479c06b 80 SUPERFAMILY SSF47336 1 79 9.16E-25 T 14-10-2018 IPR036736 ACP-like superfamily Theos_0670 b45ba09067c413d0a9da38ba6479c06b 80 Gene3D G3DSA:1.10.1200.10 1 79 1.0E-30 T 14-10-2018 IPR036736 ACP-like superfamily Theos_1681 0e1f79595d3a75934dd34ee91502f983 241 Gene3D G3DSA:3.40.1390.30 6 229 4.5E-84 T 14-10-2018 Theos_1681 0e1f79595d3a75934dd34ee91502f983 241 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 228 1.8E-50 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Theos_1681 0e1f79595d3a75934dd34ee91502f983 241 Gene3D G3DSA:3.40.1390.30 96 212 4.5E-84 T 14-10-2018 Theos_1681 0e1f79595d3a75934dd34ee91502f983 241 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 2 239 5.1E-45 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Theos_1681 0e1f79595d3a75934dd34ee91502f983 241 SUPERFAMILY SSF102705 1 240 1.14E-63 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 Pfam PF13412 Winged helix-turn-helix DNA-binding 24 63 1.0E-7 T 14-10-2018 Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 Pfam PF00480 ROK family 97 273 7.6E-30 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 Gene3D G3DSA:3.30.420.40 94 213 1.8E-47 T 14-10-2018 Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 SUPERFAMILY SSF53067 90 364 4.59E-36 T 14-10-2018 Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 Gene3D G3DSA:3.30.420.40 214 279 1.8E-47 T 14-10-2018 Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 SUPERFAMILY SSF46785 18 82 6.25E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 ProSitePatterns PS01125 ROK family signature. 222 249 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 Gene3D G3DSA:3.30.420.40 346 356 1.8E-8 T 14-10-2018 Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 Gene3D G3DSA:1.10.10.10 22 83 1.7E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1294 e111ed09ae726d1156fdc74f107da9e2 375 Gene3D G3DSA:3.30.420.40 281 345 1.8E-8 T 14-10-2018 Theos_1540 5582fe0c240291b252e600e22f811a17 300 Gene3D G3DSA:1.10.620.20 1 291 5.4E-102 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 Theos_1540 5582fe0c240291b252e600e22f811a17 300 Pfam PF00268 Ribonucleotide reductase, small chain 19 251 3.2E-20 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Theos_1540 5582fe0c240291b252e600e22f811a17 300 SUPERFAMILY SSF47240 13 281 1.29E-47 T 14-10-2018 IPR009078 Ferritin-like superfamily Theos_0065 b8b46197347ea7fdbfc168304bc76443 280 Pfam PF01875 Memo-like protein 8 259 4.1E-43 T 14-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 Theos_0065 b8b46197347ea7fdbfc168304bc76443 280 Gene3D G3DSA:3.40.830.10 3 263 3.4E-52 T 14-10-2018 Theos_0065 b8b46197347ea7fdbfc168304bc76443 280 Hamap MF_00055 MEMO1 family protein . 3 262 43.336 T 14-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 Theos_0065 b8b46197347ea7fdbfc168304bc76443 280 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 5 260 4.3E-67 T 14-10-2018 Theos_1240 f823adeb1f7a67ec4d73d9bc436b21fb 124 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 26 6.5E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1240 f823adeb1f7a67ec4d73d9bc436b21fb 124 SUPERFAMILY SSF54523 7 104 5.02E-16 T 14-10-2018 Theos_1240 f823adeb1f7a67ec4d73d9bc436b21fb 124 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1240 f823adeb1f7a67ec4d73d9bc436b21fb 124 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 3.2E-10 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1240 f823adeb1f7a67ec4d73d9bc436b21fb 124 Gene3D G3DSA:3.30.700.10 7 123 1.1E-20 T 14-10-2018 Theos_0022 d64d01523962bc24a0b03edb25fd28c7 194 SUPERFAMILY SSF52833 39 193 1.46E-39 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0022 d64d01523962bc24a0b03edb25fd28c7 194 Gene3D G3DSA:3.40.30.10 24 194 8.5E-54 T 14-10-2018 Theos_0022 d64d01523962bc24a0b03edb25fd28c7 194 Pfam PF02630 SCO1/SenC 49 173 2.4E-31 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_2358 a631a6674ac831d77867fc1618c68346 296 Pfam PF01497 Periplasmic binding protein 41 235 6.3E-21 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain Theos_2358 a631a6674ac831d77867fc1618c68346 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 275 288 8.6E-7 T 14-10-2018 Theos_2358 a631a6674ac831d77867fc1618c68346 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 214 232 8.6E-7 T 14-10-2018 Theos_2358 a631a6674ac831d77867fc1618c68346 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 58 76 8.6E-7 T 14-10-2018 Theos_2358 a631a6674ac831d77867fc1618c68346 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 88 103 8.6E-7 T 14-10-2018 Theos_2358 a631a6674ac831d77867fc1618c68346 296 SUPERFAMILY SSF53807 22 286 3.34E-44 T 14-10-2018 Theos_2358 a631a6674ac831d77867fc1618c68346 296 Gene3D G3DSA:3.40.50.1980 126 296 1.5E-26 T 14-10-2018 Theos_2358 a631a6674ac831d77867fc1618c68346 296 Gene3D G3DSA:3.40.50.1980 25 124 9.9E-23 T 14-10-2018 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 SUPERFAMILY SSF51905 14 316 6.39E-59 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 Gene3D G3DSA:3.50.50.60 18 308 6.3E-125 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 1.7E-40 T 14-10-2018 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 1.7E-40 T 14-10-2018 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 1.7E-40 T 14-10-2018 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 1.7E-40 T 14-10-2018 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 1.7E-40 T 14-10-2018 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 18 305 4.6E-52 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 Gene3D G3DSA:3.50.50.60 129 251 6.3E-125 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 207 223 2.7E-74 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 2.7E-74 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 2.7E-74 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 152 2.7E-74 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 297 2.7E-74 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 73 83 2.7E-74 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 245 266 2.7E-74 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 118 126 2.7E-74 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 52 67 2.7E-74 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 147 167 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 Theos_0221 953a4c140349f91ed0f61d969dd92dc9 326 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 316 6.6E-121 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 Theos_0263 4078905356c1383af40939671a230d2d 370 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 14 357 6.5E-151 T 14-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 Theos_0263 4078905356c1383af40939671a230d2d 370 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 205 219 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Theos_0263 4078905356c1383af40939671a230d2d 370 SUPERFAMILY SSF52540 17 349 2.94E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0263 4078905356c1383af40939671a230d2d 370 Gene3D G3DSA:3.30.450.90 4 111 7.1E-41 T 14-10-2018 Theos_0263 4078905356c1383af40939671a230d2d 370 Gene3D G3DSA:3.40.50.300 112 370 2.5E-92 T 14-10-2018 Theos_0263 4078905356c1383af40939671a230d2d 370 Pfam PF00437 Type II/IV secretion system protein 21 267 2.6E-43 T 14-10-2018 IPR001482 Type II/IV secretion system protein Theos_1097 813ebc7b834bf3aba8b0d50437605121 226 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 20 221 2.0E-40 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Theos_1097 813ebc7b834bf3aba8b0d50437605121 226 SUPERFAMILY SSF88697 4 66 7.29E-30 T 14-10-2018 IPR015947 PUA-like superfamily Theos_1097 813ebc7b834bf3aba8b0d50437605121 226 Pfam PF04452 RNA methyltransferase 18 222 3.6E-53 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Theos_1097 813ebc7b834bf3aba8b0d50437605121 226 SUPERFAMILY SSF75217 68 221 4.92E-44 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Theos_1097 813ebc7b834bf3aba8b0d50437605121 226 Gene3D G3DSA:2.40.240.20 1 66 1.2E-30 T 14-10-2018 Theos_1097 813ebc7b834bf3aba8b0d50437605121 226 PIRSF PIRSF015601 13 225 4.0E-53 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Theos_1097 813ebc7b834bf3aba8b0d50437605121 226 Gene3D G3DSA:3.40.1280.10 67 226 2.1E-58 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Theos_0251 1ebe09c3f43214a75f61d0d6624da37b 385 SMART SM00981 73 160 5.2E-11 T 14-10-2018 IPR004114 THUMP domain GO:0003723 Theos_0251 1ebe09c3f43214a75f61d0d6624da37b 385 SUPERFAMILY SSF52402 171 371 9.92E-50 T 14-10-2018 Theos_0251 1ebe09c3f43214a75f61d0d6624da37b 385 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 170 363 1.5E-70 T 14-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 Theos_0251 1ebe09c3f43214a75f61d0d6624da37b 385 Pfam PF02926 THUMP domain 64 155 1.4E-9 T 14-10-2018 IPR004114 THUMP domain GO:0003723 Theos_0251 1ebe09c3f43214a75f61d0d6624da37b 385 Gene3D G3DSA:3.30.2130.30 1 168 1.7E-32 T 14-10-2018 Theos_0251 1ebe09c3f43214a75f61d0d6624da37b 385 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 8 368 3.5E-99 T 14-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 Theos_0251 1ebe09c3f43214a75f61d0d6624da37b 385 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 385 116.568 T 14-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 Theos_0251 1ebe09c3f43214a75f61d0d6624da37b 385 Gene3D G3DSA:3.40.50.620 170 380 2.2E-72 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0251 1ebe09c3f43214a75f61d0d6624da37b 385 SUPERFAMILY SSF143437 3 168 4.53E-30 T 14-10-2018 Theos_2107 43aebedcb0a3cd52340fa5b04cf04c39 126 SUPERFAMILY SSF111038 3 124 3.53E-37 T 14-10-2018 IPR035917 YjbQ-like superfamily Theos_2107 43aebedcb0a3cd52340fa5b04cf04c39 126 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 7 124 7.9E-35 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 Theos_2107 43aebedcb0a3cd52340fa5b04cf04c39 126 Pfam PF01894 Uncharacterised protein family UPF0047 15 123 1.1E-31 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 Theos_2107 43aebedcb0a3cd52340fa5b04cf04c39 126 Gene3D G3DSA:2.60.120.460 1 125 6.3E-48 T 14-10-2018 IPR035917 YjbQ-like superfamily Theos_2107 43aebedcb0a3cd52340fa5b04cf04c39 126 PIRSF PIRSF004681 1 126 7.8E-36 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 Theos_1760 7d47de15b5ee85d754acb4c669701e0c 136 Pfam PF00293 NUDIX domain 10 129 7.6E-23 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Theos_1760 7d47de15b5ee85d754acb4c669701e0c 136 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Theos_1760 7d47de15b5ee85d754acb4c669701e0c 136 PRINTS PR00502 NUDIX hydrolase family signature 34 48 5.8E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_1760 7d47de15b5ee85d754acb4c669701e0c 136 PRINTS PR00502 NUDIX hydrolase family signature 48 63 5.8E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_1760 7d47de15b5ee85d754acb4c669701e0c 136 SUPERFAMILY SSF55811 6 135 6.09E-30 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Theos_1760 7d47de15b5ee85d754acb4c669701e0c 136 Gene3D G3DSA:3.90.79.10 2 136 7.9E-29 T 14-10-2018 Theos_2050 9a42ed6202e7141faed593db27dea614 79 SUPERFAMILY SSF54786 6 71 3.3E-18 T 14-10-2018 Theos_2050 9a42ed6202e7141faed593db27dea614 79 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 11 66 5.4E-21 T 14-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Theos_2050 9a42ed6202e7141faed593db27dea614 79 Gene3D G3DSA:3.30.920.30 8 73 6.9E-23 T 14-10-2018 IPR038570 HicA superfamily Theos_1948 27e0484c80e882e4a00edba2dea54420 184 Pfam PF02357 Transcription termination factor nusG 4 113 3.7E-25 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 Gene3D G3DSA:2.30.30.30 124 183 4.2E-27 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 Gene3D G3DSA:3.30.70.940 2 120 2.7E-47 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 PRINTS PR00338 Transcription termination factor NUSG signature 58 70 1.6E-21 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 PRINTS PR00338 Transcription termination factor NUSG signature 160 176 1.6E-21 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 PRINTS PR00338 Transcription termination factor NUSG signature 142 157 1.6E-21 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 183 6.4E-62 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 SMART SM00739 130 157 3.9E-8 T 14-10-2018 IPR005824 KOW Theos_1948 27e0484c80e882e4a00edba2dea54420 184 SUPERFAMILY SSF82679 4 114 1.11E-38 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 ProSitePatterns PS01014 Transcription termination factor nusG signature. 167 176 - T 14-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site Theos_1948 27e0484c80e882e4a00edba2dea54420 184 SMART SM00738 2 116 1.3E-49 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 Pfam PF00467 KOW motif 133 164 6.2E-10 T 14-10-2018 IPR005824 KOW Theos_1948 27e0484c80e882e4a00edba2dea54420 184 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 184 25.984 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Theos_1948 27e0484c80e882e4a00edba2dea54420 184 SUPERFAMILY SSF50104 119 183 7.74E-20 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Theos_0571 b504ea10c479ab24c02adfa222ed5678 150 Gene3D G3DSA:3.10.590.10 1 148 1.4E-51 T 14-10-2018 Theos_0571 b504ea10c479ab24c02adfa222ed5678 150 SUPERFAMILY SSF88697 1 146 9.11E-55 T 14-10-2018 IPR015947 PUA-like superfamily Theos_0571 b504ea10c479ab24c02adfa222ed5678 150 Pfam PF01878 EVE domain 2 144 1.7E-47 T 14-10-2018 IPR002740 EVE domain Theos_0714 5a9983a435064d979fafecfc531bbb65 206 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 28 154 2.4E-39 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0714 5a9983a435064d979fafecfc531bbb65 206 Gene3D G3DSA:3.30.460.80 1 134 1.3E-50 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0714 5a9983a435064d979fafecfc531bbb65 206 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 115 136 - T 14-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0714 5a9983a435064d979fafecfc531bbb65 206 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 36 153 7.3E-37 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0714 5a9983a435064d979fafecfc531bbb65 206 SUPERFAMILY SSF143243 6 181 6.54E-52 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0714 5a9983a435064d979fafecfc531bbb65 206 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 86 137 2.0E-22 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0714 5a9983a435064d979fafecfc531bbb65 206 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 3 162 30.397 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0105 64da4bf3ba0d9636db447df716b141af 253 Pfam PF01261 Xylose isomerase-like TIM barrel 41 214 3.9E-20 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Theos_0105 64da4bf3ba0d9636db447df716b141af 253 SUPERFAMILY SSF51658 10 249 1.11E-37 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily Theos_0105 64da4bf3ba0d9636db447df716b141af 253 Gene3D G3DSA:3.20.20.150 5 249 4.2E-45 T 14-10-2018 Theos_0534 1b0c6ba61a695c4a7c3cb70888b651f5 357 SUPERFAMILY SSF102114 85 337 5.23E-26 T 14-10-2018 Theos_0534 1b0c6ba61a695c4a7c3cb70888b651f5 357 Pfam PF04055 Radical SAM superfamily 124 284 2.6E-12 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_0534 1b0c6ba61a695c4a7c3cb70888b651f5 357 SMART SM00729 118 338 1.4E-20 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_0534 1b0c6ba61a695c4a7c3cb70888b651f5 357 Gene3D G3DSA:3.20.20.70 111 345 2.4E-12 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_2425 814ee30b9d6a30ab76f212b793964ddd 196 Gene3D G3DSA:1.10.490.10 16 170 2.5E-21 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Theos_2425 814ee30b9d6a30ab76f212b793964ddd 196 Pfam PF11563 Protoglobin 22 160 2.6E-16 T 14-10-2018 Theos_2425 814ee30b9d6a30ab76f212b793964ddd 196 SUPERFAMILY SSF46458 14 156 3.74E-13 T 14-10-2018 IPR009050 Globin-like superfamily Theos_0715 d973d34ea73d02f208cdcab7a06f2ed2 179 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 126 142 - T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0715 d973d34ea73d02f208cdcab7a06f2ed2 179 Gene3D G3DSA:3.40.50.12280 1 179 8.5E-91 T 14-10-2018 Theos_0715 d973d34ea73d02f208cdcab7a06f2ed2 179 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 45 154 6.8E-26 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0715 d973d34ea73d02f208cdcab7a06f2ed2 179 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 19 160 7.7E-75 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0715 d973d34ea73d02f208cdcab7a06f2ed2 179 SUPERFAMILY SSF56770 17 165 4.97E-68 T 14-10-2018 Theos_0715 d973d34ea73d02f208cdcab7a06f2ed2 179 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 12 159 43.892 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0098 0e3454fbfd68bfd0dd0124fa03e3e704 93 Pfam PF02583 Metal-sensitive transcriptional repressor 13 91 2.7E-22 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 Theos_0098 0e3454fbfd68bfd0dd0124fa03e3e704 93 Gene3D G3DSA:1.20.58.1000 1 93 1.4E-32 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily Theos_0232 9fbf06894137434a276ac0ecfe2510d9 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 3.4E-52 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Theos_0232 9fbf06894137434a276ac0ecfe2510d9 153 Pfam PF03477 ATP cone domain 50 132 2.9E-14 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 Theos_0232 9fbf06894137434a276ac0ecfe2510d9 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 151 76.475 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Theos_2215 5f7b1aab82de457e02251b43178e7253 396 Gene3D G3DSA:3.40.50.2300 36 366 9.0E-116 T 14-10-2018 Theos_2215 5f7b1aab82de457e02251b43178e7253 396 SUPERFAMILY SSF53822 35 374 1.32E-97 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_2215 5f7b1aab82de457e02251b43178e7253 396 Pfam PF13458 Periplasmic binding protein 35 373 5.8E-83 T 14-10-2018 IPR028081 Leucine-binding protein domain Theos_2215 5f7b1aab82de457e02251b43178e7253 396 Gene3D G3DSA:3.40.50.2300 153 375 9.0E-116 T 14-10-2018 Theos_0877 5e4b9326933bcdd0540c334eed1aadba 141 Gene3D G3DSA:1.10.10.10 5 50 1.3E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0877 5e4b9326933bcdd0540c334eed1aadba 141 Gene3D G3DSA:1.10.10.10 52 93 9.3E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0877 5e4b9326933bcdd0540c334eed1aadba 141 Hamap MF_01114 Regulatory protein RecX [recX]. 2 139 13.622 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 Theos_0877 5e4b9326933bcdd0540c334eed1aadba 141 Pfam PF02631 RecX family 29 133 3.0E-21 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 Theos_2346 cf6607eea640ef627d5e5f7f4c11911e 271 SUPERFAMILY SSF161098 4 271 4.58E-64 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2346 cf6607eea640ef627d5e5f7f4c11911e 271 Gene3D G3DSA:1.10.3720.10 5 262 8.8E-60 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2346 cf6607eea640ef627d5e5f7f4c11911e 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 263 1.1E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2466 67eee2954ec40b0b08d0917d445166b4 273 SUPERFAMILY SSF161098 4 273 7.01E-72 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2466 67eee2954ec40b0b08d0917d445166b4 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 262 2.2E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2466 67eee2954ec40b0b08d0917d445166b4 273 Gene3D G3DSA:1.10.3720.10 1 264 7.3E-65 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2441 041f0b029361b2bdb635181ed0cca9cb 257 SUPERFAMILY SSF161098 53 237 1.44E-28 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2441 041f0b029361b2bdb635181ed0cca9cb 257 Gene3D G3DSA:1.10.3720.10 53 246 4.0E-22 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2441 041f0b029361b2bdb635181ed0cca9cb 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 245 7.3E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 Pfam PF00557 Metallopeptidase family M24 129 340 8.1E-66 T 14-10-2018 IPR000994 Peptidase M24 Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 278 290 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 Gene3D G3DSA:3.90.230.10 123 355 2.6E-78 T 14-10-2018 Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 SUPERFAMILY SSF55920 123 353 2.09E-73 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 SUPERFAMILY SSF53092 7 121 2.27E-19 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 Gene3D G3DSA:3.40.350.10 3 120 8.2E-23 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 121 6.0E-21 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 308 320 5.5E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 273 285 5.5E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_1467 b25e3c0faafa1bdd11b7c03a7853668f 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 202 218 5.5E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Theos_2390 73f7be9ae2b69d7082b13237c8090e6e 424 Gene3D G3DSA:3.40.190.10 26 374 5.3E-89 T 14-10-2018 Theos_2390 73f7be9ae2b69d7082b13237c8090e6e 424 Gene3D G3DSA:3.40.190.10 142 411 5.3E-89 T 14-10-2018 Theos_2390 73f7be9ae2b69d7082b13237c8090e6e 424 SUPERFAMILY SSF53850 22 414 1.09E-76 T 14-10-2018 Theos_2390 73f7be9ae2b69d7082b13237c8090e6e 424 Pfam PF13416 Bacterial extracellular solute-binding protein 41 347 1.8E-36 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_0843 506cbab2c812e0c871b17278d30d2665 660 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 29 659 3.0E-200 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ Theos_0843 506cbab2c812e0c871b17278d30d2665 660 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 125 587 4.7E-81 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Theos_0843 506cbab2c812e0c871b17278d30d2665 660 Pfam PF11874 Domain of unknown function (DUF3394) 594 644 7.6E-7 T 14-10-2018 IPR021814 Protein of unknown function DUF3394 Theos_2031 3fd364d388588b77de6fb73cc2856487 139 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 7 138 2.0E-40 T 14-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 Theos_2031 3fd364d388588b77de6fb73cc2856487 139 Pfam PF01951 Archease protein family (MTH1598/TM1083) 6 139 2.6E-33 T 14-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 Theos_2031 3fd364d388588b77de6fb73cc2856487 139 Gene3D G3DSA:3.55.10.10 3 139 3.5E-37 T 14-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 Theos_2031 3fd364d388588b77de6fb73cc2856487 139 SUPERFAMILY SSF69819 4 139 4.97E-37 T 14-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 Theos_2137 3c7f1cd2a40dfc4b35077f9d94dbf02b 359 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 322 1.1E-65 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Theos_2137 3c7f1cd2a40dfc4b35077f9d94dbf02b 359 PIRSF PIRSF039026 1 355 4.7E-133 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like Theos_2137 3c7f1cd2a40dfc4b35077f9d94dbf02b 359 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 25 1.2E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Theos_2137 3c7f1cd2a40dfc4b35077f9d94dbf02b 359 Gene3D G3DSA:3.40.190.170 32 336 1.5E-131 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Theos_2137 3c7f1cd2a40dfc4b35077f9d94dbf02b 359 Gene3D G3DSA:3.40.190.10 152 322 1.5E-131 T 14-10-2018 Theos_2137 3c7f1cd2a40dfc4b35077f9d94dbf02b 359 SUPERFAMILY SSF53850 156 294 2.53E-7 T 14-10-2018 Theos_0428 be82123ab22d25e3c96d3888bb58909d 194 SUPERFAMILY SSF69593 16 136 3.66E-22 T 14-10-2018 Theos_0428 be82123ab22d25e3c96d3888bb58909d 194 SMART SM00563 32 141 8.9E-21 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Theos_0428 be82123ab22d25e3c96d3888bb58909d 194 Pfam PF01553 Acyltransferase 23 136 5.3E-14 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Theos_1005 da08e891a104fe04de81285d21cdda50 360 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 328 5.5E-47 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Theos_1005 da08e891a104fe04de81285d21cdda50 360 PIRSF PIRSF039026 3 360 3.4E-111 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like Theos_1005 da08e891a104fe04de81285d21cdda50 360 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 23 4.1E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Theos_1005 da08e891a104fe04de81285d21cdda50 360 Gene3D G3DSA:3.40.190.170 32 360 1.4E-135 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 Gene3D G3DSA:1.10.760.10 261 326 4.6E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 Gene3D G3DSA:1.25.40.10 125 260 6.3E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 SMART SM00028 171 204 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 SMART SM00028 205 238 0.1 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 SMART SM00028 137 170 0.16 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 257 323 2.8E-12 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 SUPERFAMILY SSF46626 235 326 4.03E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 Pfam PF13432 Tetratricopeptide repeat 141 204 2.1E-7 T 14-10-2018 Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 SUPERFAMILY SSF48452 137 240 2.06E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1604 6aee8cf3dc087bc7a2845352c4d9c3ca 326 Pfam PF13181 Tetratricopeptide repeat 205 233 9.0E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_1073 3ad1d3019b0a4deec8f0c2c2e1b7a845 137 Gene3D G3DSA:3.90.1010.10 1 135 6.5E-45 T 14-10-2018 Theos_1073 3ad1d3019b0a4deec8f0c2c2e1b7a845 137 SUPERFAMILY SSF82649 3 132 2.56E-22 T 14-10-2018 Theos_1073 3ad1d3019b0a4deec8f0c2c2e1b7a845 137 Pfam PF02657 Fe-S metabolism associated domain 18 128 2.0E-21 T 14-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like Theos_0698 c4ce1194a5f847881fcb045e755a25e6 210 Pfam PF01694 Rhomboid family 56 207 7.9E-39 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Theos_0698 c4ce1194a5f847881fcb045e755a25e6 210 SUPERFAMILY SSF144091 11 209 1.7E-43 T 14-10-2018 Theos_0698 c4ce1194a5f847881fcb045e755a25e6 210 Gene3D G3DSA:1.20.1540.10 8 206 1.3E-34 T 14-10-2018 IPR035952 Rhomboid-like superfamily Theos_0937 1d3c100295ecc0335cb0fe658ff132f1 118 Gene3D G3DSA:3.30.70.240 1 75 5.8E-31 T 14-10-2018 Theos_0937 1d3c100295ecc0335cb0fe658ff132f1 118 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 1 86 6.9E-34 T 14-10-2018 IPR010152 CRISPR-associated protein Cas2 subtype Theos_0937 1d3c100295ecc0335cb0fe658ff132f1 118 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 1 86 5.3E-18 T 14-10-2018 IPR010152 CRISPR-associated protein Cas2 subtype Theos_1877 b12d8acdb76b3acf47a1f3505c69cd85 228 Gene3D G3DSA:3.40.109.10 16 228 1.7E-40 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Theos_1877 b12d8acdb76b3acf47a1f3505c69cd85 228 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 83 227 9.8E-25 T 14-10-2018 IPR020051 SagB-type dehydrogenase domain Theos_1877 b12d8acdb76b3acf47a1f3505c69cd85 228 SUPERFAMILY SSF55469 91 227 7.07E-15 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Theos_1877 b12d8acdb76b3acf47a1f3505c69cd85 228 Pfam PF00881 Nitroreductase family 91 227 1.6E-11 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Theos_1209 59dff8823c9a2508797cd42852088638 576 SUPERFAMILY SSF56519 41 213 3.53E-27 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 Theos_1209 59dff8823c9a2508797cd42852088638 576 Gene3D G3DSA:3.40.710.10 213 576 2.3E-85 T 14-10-2018 Theos_1209 59dff8823c9a2508797cd42852088638 576 SUPERFAMILY SSF56601 165 574 1.57E-79 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Theos_1209 59dff8823c9a2508797cd42852088638 576 Pfam PF00905 Penicillin binding protein transpeptidase domain 250 569 1.4E-51 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Theos_1209 59dff8823c9a2508797cd42852088638 576 Gene3D G3DSA:3.90.1310.30 41 212 1.3E-20 T 14-10-2018 Theos_1209 59dff8823c9a2508797cd42852088638 576 Pfam PF03717 Penicillin-binding Protein dimerisation domain 48 198 1.4E-16 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Theos_1847 fa2f35c6c2f992b4a3f8086ac7007a04 264 SUPERFAMILY SSF53850 16 238 1.52E-22 T 14-10-2018 Theos_1847 fa2f35c6c2f992b4a3f8086ac7007a04 264 Pfam PF12849 PBP superfamily domain 18 230 7.4E-17 T 14-10-2018 IPR024370 PBP domain Theos_1847 fa2f35c6c2f992b4a3f8086ac7007a04 264 Gene3D G3DSA:3.40.190.10 18 238 1.3E-73 T 14-10-2018 Theos_1847 fa2f35c6c2f992b4a3f8086ac7007a04 264 Gene3D G3DSA:3.40.190.10 93 206 1.3E-73 T 14-10-2018 Theos_2461 d2cd21bdea5b0584ec8783c775f70dcb 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 24 281 9.1E-35 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 Gene3D G3DSA:1.25.40.10 379 453 7.9E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 Pfam PF13432 Tetratricopeptide repeat 28 83 3.4E-8 T 14-10-2018 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 Pfam PF13432 Tetratricopeptide repeat 162 218 0.0089 T 14-10-2018 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 Pfam PF13432 Tetratricopeptide repeat 243 287 1.8E-4 T 14-10-2018 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 Gene3D G3DSA:1.25.40.10 20 240 1.1E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SMART SM00028 192 225 300.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SMART SM00028 58 91 10.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SMART SM00028 158 191 230.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SMART SM00028 346 379 4.1 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SMART SM00028 24 57 190.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SMART SM00028 413 446 2.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SMART SM00028 92 125 0.0041 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SMART SM00028 256 289 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SUPERFAMILY SSF48452 345 450 1.66E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 Gene3D G3DSA:1.25.40.10 242 378 1.0E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SUPERFAMILY SSF48452 248 372 1.19E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 SUPERFAMILY SSF48452 25 219 4.3E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 Pfam PF07719 Tetratricopeptide repeat 93 124 1.9E-5 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 Pfam PF14559 Tetratricopeptide repeat 356 416 8.3E-6 T 14-10-2018 Theos_0310 77286b022f9b81ac6ee75c6db26e5eb0 453 Pfam PF07721 Tetratricopeptide repeat 317 341 0.011 T 14-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 Theos_1922 93006f34b1ae3f701294286d75bea95e 363 PIRSF PIRSF006004 15 356 1.9E-132 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 Theos_1922 93006f34b1ae3f701294286d75bea95e 363 Pfam PF04055 Radical SAM superfamily 112 278 1.1E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_1922 93006f34b1ae3f701294286d75bea95e 363 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 29 345 2.5E-112 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 Theos_1922 93006f34b1ae3f701294286d75bea95e 363 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 15 350 69.092 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 Theos_1922 93006f34b1ae3f701294286d75bea95e 363 SUPERFAMILY SSF102114 103 314 1.7E-18 T 14-10-2018 Theos_1922 93006f34b1ae3f701294286d75bea95e 363 Gene3D G3DSA:1.10.150.530 19 69 8.3E-12 T 14-10-2018 Theos_1922 93006f34b1ae3f701294286d75bea95e 363 Gene3D G3DSA:3.20.20.70 72 335 1.7E-98 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0481 32846a54a726d8dd7456da966dae57ad 415 Gene3D G3DSA:3.30.565.10 278 414 2.9E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0481 32846a54a726d8dd7456da966dae57ad 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 410 3.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0481 32846a54a726d8dd7456da966dae57ad 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 3.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0481 32846a54a726d8dd7456da966dae57ad 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 373 3.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0481 32846a54a726d8dd7456da966dae57ad 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 3.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0481 32846a54a726d8dd7456da966dae57ad 415 Gene3D G3DSA:1.10.287.130 164 276 9.7E-23 T 14-10-2018 Theos_0481 32846a54a726d8dd7456da966dae57ad 415 SMART SM00388 213 275 3.5E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0481 32846a54a726d8dd7456da966dae57ad 415 Pfam PF00512 His Kinase A (phospho-acceptor) domain 215 275 9.6E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0481 32846a54a726d8dd7456da966dae57ad 415 SUPERFAMILY SSF47384 196 275 4.32E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_0481 32846a54a726d8dd7456da966dae57ad 415 SUPERFAMILY SSF55874 264 411 3.14E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0481 32846a54a726d8dd7456da966dae57ad 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 411 4.7E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0481 32846a54a726d8dd7456da966dae57ad 415 SMART SM00387 309 413 1.2E-35 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1510 bdefd1af5578c2141988a2de2a0a2246 247 Gene3D G3DSA:3.40.50.620 1 246 7.5E-70 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1510 bdefd1af5578c2141988a2de2a0a2246 247 SMART SM00893 21 208 1.1E-45 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Theos_1510 bdefd1af5578c2141988a2de2a0a2246 247 PIRSF PIRSF000090 1 247 4.4E-65 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 Theos_1510 bdefd1af5578c2141988a2de2a0a2246 247 SUPERFAMILY SSF52402 1 230 7.67E-62 T 14-10-2018 Theos_1510 bdefd1af5578c2141988a2de2a0a2246 247 Pfam PF01012 Electron transfer flavoprotein domain 30 202 2.2E-39 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Theos_0995 6f7ee4e0964d143de8be1d52d6e32fc9 370 Gene3D G3DSA:3.30.9.10 78 301 1.9E-87 T 14-10-2018 Theos_0995 6f7ee4e0964d143de8be1d52d6e32fc9 370 Gene3D G3DSA:3.50.50.60 3 338 1.9E-87 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0995 6f7ee4e0964d143de8be1d52d6e32fc9 370 SUPERFAMILY SSF51905 1 360 1.1E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0995 6f7ee4e0964d143de8be1d52d6e32fc9 370 Pfam PF01266 FAD dependent oxidoreductase 3 338 2.0E-56 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Theos_1993 51afe5533405fe322661917833b5bd4b 461 SUPERFAMILY SSF56322 5 456 5.49E-152 T 14-10-2018 IPR005801 ADC synthase GO:0009058 Theos_1993 51afe5533405fe322661917833b5bd4b 461 PRINTS PR00095 Anthranilate synthase component I signature 294 307 1.7E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Theos_1993 51afe5533405fe322661917833b5bd4b 461 PRINTS PR00095 Anthranilate synthase component I signature 308 321 1.7E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Theos_1993 51afe5533405fe322661917833b5bd4b 461 PRINTS PR00095 Anthranilate synthase component I signature 388 402 1.7E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Theos_1993 51afe5533405fe322661917833b5bd4b 461 PRINTS PR00095 Anthranilate synthase component I signature 403 417 1.7E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Theos_1993 51afe5533405fe322661917833b5bd4b 461 Pfam PF04715 Anthranilate synthase component I, N terminal region 13 148 9.6E-32 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Theos_1993 51afe5533405fe322661917833b5bd4b 461 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 12 455 1.0E-159 T 14-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Theos_1993 51afe5533405fe322661917833b5bd4b 461 Gene3D G3DSA:3.60.120.10 1 460 3.0E-173 T 14-10-2018 IPR005801 ADC synthase GO:0009058 Theos_1993 51afe5533405fe322661917833b5bd4b 461 Pfam PF00425 chorismate binding enzyme 193 446 6.9E-96 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal Theos_1731 363df6b353573cb9b6b387121658c118 222 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 200 2.3E-79 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Theos_1731 363df6b353573cb9b6b387121658c118 222 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Theos_1731 363df6b353573cb9b6b387121658c118 222 PIRSF PIRSF001461 1 219 9.5E-89 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Theos_1731 363df6b353573cb9b6b387121658c118 222 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 213 5.3E-87 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Theos_1731 363df6b353573cb9b6b387121658c118 222 SUPERFAMILY SSF51366 2 214 9.42E-72 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Theos_1731 363df6b353573cb9b6b387121658c118 222 Gene3D G3DSA:3.20.20.70 1 218 1.2E-82 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0380 5b46875448901bd15429c6c39dd71335 388 Gene3D G3DSA:3.30.460.30 3 147 4.2E-42 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Theos_0380 5b46875448901bd15429c6c39dd71335 388 PIRSF PIRSF000445 3 374 3.6E-119 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Theos_0380 5b46875448901bd15429c6c39dd71335 388 Gene3D G3DSA:3.40.50.720 148 295 2.6E-44 T 14-10-2018 Theos_0380 5b46875448901bd15429c6c39dd71335 388 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 86 109 - T 14-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Theos_0380 5b46875448901bd15429c6c39dd71335 388 SUPERFAMILY SSF69742 4 145 1.83E-38 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Theos_0380 5b46875448901bd15429c6c39dd71335 388 SUPERFAMILY SSF51735 148 297 1.48E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0380 5b46875448901bd15429c6c39dd71335 388 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 159 288 3.0E-36 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Theos_0380 5b46875448901bd15429c6c39dd71335 388 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 6 352 4.0E-99 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Theos_0380 5b46875448901bd15429c6c39dd71335 388 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 8 143 2.4E-38 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Theos_0380 5b46875448901bd15429c6c39dd71335 388 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 388 26.341 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 SMART SM00387 193 295 6.0E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 Pfam PF13188 PAS domain 9 54 8.4E-5 T 14-10-2018 IPR000014 PAS domain Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 Gene3D G3DSA:1.10.287.130 107 156 3.0E-6 T 14-10-2018 Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 194 288 1.6E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 Pfam PF00512 His Kinase A (phospho-acceptor) domain 106 152 7.0E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 Gene3D G3DSA:3.30.565.10 170 295 3.5E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 SUPERFAMILY SSF55874 180 294 3.67E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 Gene3D G3DSA:3.30.450.20 2 106 1.8E-5 T 14-10-2018 Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 SUPERFAMILY SSF55785 18 74 6.09E-5 T 14-10-2018 IPR035965 PAS domain superfamily Theos_0173 9891c1a9d03ef2766019bab169fa5142 295 SUPERFAMILY SSF47384 89 154 1.65E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_1565 6bb23c3f2a4fb9494a3a7d3a6f1f9538 269 Gene3D G3DSA:3.40.50.10610 116 255 4.8E-6 T 14-10-2018 Theos_1565 6bb23c3f2a4fb9494a3a7d3a6f1f9538 269 Pfam PF03783 Curli production assembly/transport component CsgG 81 251 2.5E-35 T 14-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 Theos_0511 637e855e62d188c611a4d9f30bbb78d6 259 Gene3D G3DSA:3.40.50.300 1 252 1.9E-67 T 14-10-2018 Theos_0511 637e855e62d188c611a4d9f30bbb78d6 259 SMART SM00382 28 228 7.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0511 637e855e62d188c611a4d9f30bbb78d6 259 Pfam PF00005 ABC transporter 20 179 1.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0511 637e855e62d188c611a4d9f30bbb78d6 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 251 8.7E-14 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Theos_0511 637e855e62d188c611a4d9f30bbb78d6 259 SUPERFAMILY SSF52540 3 251 8.81E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0154 b8cc0e7898e0f7a64b7af9f91a897e67 129 SUPERFAMILY SSF55811 6 127 1.31E-31 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Theos_0154 b8cc0e7898e0f7a64b7af9f91a897e67 129 Gene3D G3DSA:3.90.79.10 6 127 6.9E-41 T 14-10-2018 Theos_0154 b8cc0e7898e0f7a64b7af9f91a897e67 129 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Theos_0154 b8cc0e7898e0f7a64b7af9f91a897e67 129 PRINTS PR00502 NUDIX hydrolase family signature 29 43 2.3E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_0154 b8cc0e7898e0f7a64b7af9f91a897e67 129 PRINTS PR00502 NUDIX hydrolase family signature 43 58 2.3E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Theos_0154 b8cc0e7898e0f7a64b7af9f91a897e67 129 Pfam PF00293 NUDIX domain 6 112 7.7E-21 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Theos_1839 9fd6aeb9148e251e349ccae7677de372 182 Gene3D G3DSA:3.40.50.1010 1 147 2.0E-28 T 14-10-2018 Theos_1839 9fd6aeb9148e251e349ccae7677de372 182 Pfam PF01936 NYN domain 2 144 3.7E-23 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type Theos_2181 b9d5ff16749ef880bbf6614a089e6f10 481 SUPERFAMILY SSF48452 82 232 5.06E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2181 b9d5ff16749ef880bbf6614a089e6f10 481 SUPERFAMILY SSF48452 19 133 1.7E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2181 b9d5ff16749ef880bbf6614a089e6f10 481 Gene3D G3DSA:1.25.40.10 105 247 2.3E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_2181 b9d5ff16749ef880bbf6614a089e6f10 481 Gene3D G3DSA:1.25.40.10 9 104 4.6E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_1865 fb83f77b2426847bc6a7cb71ae544541 112 SUPERFAMILY SSF101386 4 102 1.16E-23 T 14-10-2018 Theos_1865 fb83f77b2426847bc6a7cb71ae544541 112 PIRSF PIRSF029904 1 109 7.7E-43 T 14-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD Theos_1865 fb83f77b2426847bc6a7cb71ae544541 112 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 26 101 1.1E-17 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Theos_1865 fb83f77b2426847bc6a7cb71ae544541 112 Gene3D G3DSA:1.10.287.1080 2 111 9.4E-28 T 14-10-2018 Theos_1634 2c17a23abd5b08b2b7ae5a2bbb005d57 109 Gene3D G3DSA:2.40.50.140 3 109 2.2E-29 T 14-10-2018 Theos_1634 2c17a23abd5b08b2b7ae5a2bbb005d57 109 Pfam PF01588 Putative tRNA binding domain 12 105 2.0E-15 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 Theos_1634 2c17a23abd5b08b2b7ae5a2bbb005d57 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 5 108 4.9E-47 T 14-10-2018 IPR008231 Probable chaperone CsaA Theos_1634 2c17a23abd5b08b2b7ae5a2bbb005d57 109 SUPERFAMILY SSF50249 4 108 8.32E-31 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1732 740d9a7a39437c0d7772a1db2f75c23e 321 SUPERFAMILY SSF52540 4 194 6.1E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1732 740d9a7a39437c0d7772a1db2f75c23e 321 ProSitePatterns PS00567 Phosphoribulokinase signature. 150 163 - T 14-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 Theos_1732 740d9a7a39437c0d7772a1db2f75c23e 321 PRINTS PR00478 Phosphoribulokinase family signature 150 167 4.9E-15 T 14-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 Theos_1732 740d9a7a39437c0d7772a1db2f75c23e 321 PRINTS PR00478 Phosphoribulokinase family signature 12 29 4.9E-15 T 14-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 Theos_1732 740d9a7a39437c0d7772a1db2f75c23e 321 PRINTS PR00478 Phosphoribulokinase family signature 168 191 4.9E-15 T 14-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 Theos_1732 740d9a7a39437c0d7772a1db2f75c23e 321 Gene3D G3DSA:3.40.50.300 1 215 8.4E-51 T 14-10-2018 Theos_1732 740d9a7a39437c0d7772a1db2f75c23e 321 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 8 192 2.2E-37 T 14-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 Theos_0952 d4e227a96a99ab62ffa0c8ba5e4381a3 71 SUPERFAMILY SSF46689 2 67 4.12E-23 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_0952 d4e227a96a99ab62ffa0c8ba5e4381a3 71 Gene3D G3DSA:1.10.10.10 6 71 1.7E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0952 d4e227a96a99ab62ffa0c8ba5e4381a3 71 Pfam PF04255 Protein of unknown function (DUF433) 7 61 1.9E-25 T 14-10-2018 IPR007367 Protein of unknown function DUF433 Theos_0402 588f53e866c73c51de6e13fa410920b4 347 SUPERFAMILY SSF52540 6 239 5.94E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0402 588f53e866c73c51de6e13fa410920b4 347 Pfam PF00005 ABC transporter 22 159 3.7E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0402 588f53e866c73c51de6e13fa410920b4 347 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0402 588f53e866c73c51de6e13fa410920b4 347 Pfam PF08402 TOBE domain 266 327 5.6E-10 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 Theos_0402 588f53e866c73c51de6e13fa410920b4 347 SMART SM00382 31 209 5.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0402 588f53e866c73c51de6e13fa410920b4 347 Gene3D G3DSA:3.40.50.300 4 255 1.3E-73 T 14-10-2018 Theos_0402 588f53e866c73c51de6e13fa410920b4 347 SUPERFAMILY SSF50331 235 329 8.08E-12 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 Gene3D G3DSA:3.50.50.60 3 296 1.9E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 SUPERFAMILY SSF51905 1 316 1.41E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 7.0E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 131 7.0E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 7.0E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 7.0E-21 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 290 7.5E-63 T 14-10-2018 Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 Gene3D G3DSA:3.50.50.60 135 252 1.9E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.0E-16 T 14-10-2018 Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.0E-16 T 14-10-2018 Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 261 2.0E-16 T 14-10-2018 Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 2.0E-16 T 14-10-2018 Theos_1232 37714fa1ae6172077cf9e145c052b5a9 328 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 3 319 2.0E-115 T 14-10-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA Theos_0450 5268874b9cfd231b5cc085640e762c5e 257 Gene3D G3DSA:1.10.510.10 7 254 5.8E-51 T 14-10-2018 Theos_0450 5268874b9cfd231b5cc085640e762c5e 257 Pfam PF00069 Protein kinase domain 15 245 5.4E-32 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Theos_0450 5268874b9cfd231b5cc085640e762c5e 257 SMART SM00220 15 257 4.1E-30 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Theos_0450 5268874b9cfd231b5cc085640e762c5e 257 SUPERFAMILY SSF56112 8 248 1.35E-51 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Theos_0450 5268874b9cfd231b5cc085640e762c5e 257 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 125 137 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Theos_2423 9fbf0d6ef9409cae0d13af0ab0c8fd82 183 SUPERFAMILY SSF52540 3 143 1.37E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2423 9fbf0d6ef9409cae0d13af0ab0c8fd82 183 Pfam PF00071 Ras family 5 124 1.2E-4 T 14-10-2018 IPR001806 Small GTPase GO:0003924|GO:0005525 Theos_2423 9fbf0d6ef9409cae0d13af0ab0c8fd82 183 Gene3D G3DSA:3.40.50.300 2 172 3.9E-19 T 14-10-2018 Theos_0086 fb3ed46c10ff9bdd4e224d41845aa2ec 404 Gene3D G3DSA:3.90.1150.10 7 393 4.4E-172 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0086 fb3ed46c10ff9bdd4e224d41845aa2ec 404 Gene3D G3DSA:3.40.640.10 31 290 4.4E-172 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0086 fb3ed46c10ff9bdd4e224d41845aa2ec 404 Pfam PF00266 Aminotransferase class-V 20 389 3.2E-147 T 14-10-2018 IPR000192 Aminotransferase class V domain Theos_0086 fb3ed46c10ff9bdd4e224d41845aa2ec 404 SUPERFAMILY SSF53383 1 399 1.17E-128 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0086 fb3ed46c10ff9bdd4e224d41845aa2ec 404 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 399 1.8E-170 T 14-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Theos_0139 77c0e505e7ab58c9b546f4945426f03a 144 PRINTS PR01438 Universal stress protein signature 120 142 1.8E-19 T 14-10-2018 IPR006015 Universal stress protein A Theos_0139 77c0e505e7ab58c9b546f4945426f03a 144 PRINTS PR01438 Universal stress protein signature 102 114 1.8E-19 T 14-10-2018 IPR006015 Universal stress protein A Theos_0139 77c0e505e7ab58c9b546f4945426f03a 144 PRINTS PR01438 Universal stress protein signature 2 20 1.8E-19 T 14-10-2018 IPR006015 Universal stress protein A Theos_0139 77c0e505e7ab58c9b546f4945426f03a 144 Pfam PF00582 Universal stress protein family 1 142 1.1E-34 T 14-10-2018 IPR006016 UspA Theos_0139 77c0e505e7ab58c9b546f4945426f03a 144 Gene3D G3DSA:3.40.50.620 2 142 2.9E-40 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0139 77c0e505e7ab58c9b546f4945426f03a 144 SUPERFAMILY SSF52402 2 142 2.09E-39 T 14-10-2018 Theos_2150 d1865c2b7825ac92d47022fc6c460def 398 SUPERFAMILY SSF103473 13 384 3.01E-20 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_2150 d1865c2b7825ac92d47022fc6c460def 398 Gene3D G3DSA:1.20.1250.20 9 377 3.4E-19 T 14-10-2018 Theos_2150 d1865c2b7825ac92d47022fc6c460def 398 Pfam PF07690 Major Facilitator Superfamily 15 261 4.2E-9 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_0740 558e2d2b72f83be38d62e9c58ef93d1e 117 Pfam PF01883 Iron-sulfur cluster assembly protein 17 90 1.7E-23 T 14-10-2018 IPR002744 MIP18 family-like Theos_0740 558e2d2b72f83be38d62e9c58ef93d1e 117 SUPERFAMILY SSF117916 15 111 4.58E-34 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Theos_0740 558e2d2b72f83be38d62e9c58ef93d1e 117 Gene3D G3DSA:3.30.300.130 14 113 1.9E-38 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Theos_0820 52b10983e2741b4f7da7e6501d88fd24 106 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 83 2.2E-12 T 14-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0820 52b10983e2741b4f7da7e6501d88fd24 106 SUPERFAMILY SSF159468 3 105 1.44E-20 T 14-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0820 52b10983e2741b4f7da7e6501d88fd24 106 Gene3D G3DSA:3.40.50.10580 3 102 7.0E-19 T 14-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0677 63bcdf77ff32c530ef907b52651ec7b1 160 Pfam PF11159 Protein of unknown function (DUF2939) 13 102 4.6E-27 T 14-10-2018 IPR021330 Protein of unknown function DUF2939 Theos_2477 63d7d0c8e1708e818b747e7e9c234aa2 219 Gene3D G3DSA:2.40.50.90 24 148 2.7E-25 T 14-10-2018 IPR035437 SNase-like, OB-fold superfamily Theos_2477 63d7d0c8e1708e818b747e7e9c234aa2 219 SUPERFAMILY SSF50199 25 148 8.89E-34 T 14-10-2018 Theos_2477 63d7d0c8e1708e818b747e7e9c234aa2 219 Pfam PF00565 Staphylococcal nuclease homologue 38 141 3.4E-14 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 Theos_2477 63d7d0c8e1708e818b747e7e9c234aa2 219 SMART SM00318 18 142 3.3E-25 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 Theos_0732 d7a670218698ed9549069004b4b2bd02 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Theos_0732 d7a670218698ed9549069004b4b2bd02 306 SUPERFAMILY SSF53613 1 296 3.43E-68 T 14-10-2018 IPR029056 Ribokinase-like Theos_0732 d7a670218698ed9549069004b4b2bd02 306 Pfam PF00294 pfkB family carbohydrate kinase 4 293 1.4E-47 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB Theos_0732 d7a670218698ed9549069004b4b2bd02 306 PRINTS PR00990 Ribokinase signature 32 51 2.0E-8 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Theos_0732 d7a670218698ed9549069004b4b2bd02 306 PRINTS PR00990 Ribokinase signature 104 117 2.0E-8 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Theos_0732 d7a670218698ed9549069004b4b2bd02 306 PRINTS PR00990 Ribokinase signature 5 26 2.0E-8 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Theos_0732 d7a670218698ed9549069004b4b2bd02 306 PRINTS PR00990 Ribokinase signature 219 230 2.0E-8 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Theos_0732 d7a670218698ed9549069004b4b2bd02 306 Gene3D G3DSA:3.40.1190.20 1 305 1.8E-70 T 14-10-2018 IPR029056 Ribokinase-like Theos_1422 8931c084894e6e4bd164087479a31adc 248 SUPERFAMILY SSF53474 57 203 3.81E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1422 8931c084894e6e4bd164087479a31adc 248 Gene3D G3DSA:3.40.50.1820 146 204 8.2E-8 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1422 8931c084894e6e4bd164087479a31adc 248 Gene3D G3DSA:3.40.50.1820 37 145 1.8E-5 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1422 8931c084894e6e4bd164087479a31adc 248 Pfam PF12695 Alpha/beta hydrolase family 65 222 7.1E-46 T 14-10-2018 IPR029059 Alpha/beta hydrolase fold-5 Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 6 65 1.0E-18 T 14-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 SUPERFAMILY SSF50037 133 218 2.2E-8 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 SMART SM00529 29 128 2.3E-46 T 14-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 Gene3D G3DSA:2.30.30.90 147 221 3.7E-6 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 Gene3D G3DSA:1.10.10.10 5 140 5.4E-54 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 68 136 6.9E-30 T 14-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 SMART SM00899 148 218 5.1E-8 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 SUPERFAMILY SSF46785 6 66 6.93E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 SUPERFAMILY SSF47979 68 141 8.63E-27 T 14-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 Theos_1079 e201f90d1d9665355801b5e3c3c13845 222 Pfam PF04023 FeoA domain 149 217 1.9E-8 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Theos_0603 e2b4ae2f6ede4b437348a717a09260dd 163 SMART SM00935 12 162 5.6E-23 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 Theos_0603 e2b4ae2f6ede4b437348a717a09260dd 163 SUPERFAMILY SSF111384 28 162 9.55E-21 T 14-10-2018 Theos_0603 e2b4ae2f6ede4b437348a717a09260dd 163 Pfam PF03938 Outer membrane protein (OmpH-like) 10 161 4.3E-21 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 Theos_0603 e2b4ae2f6ede4b437348a717a09260dd 163 Gene3D G3DSA:3.30.910.20 19 162 8.6E-19 T 14-10-2018 IPR024930 Skp domain superfamily Theos_1836 f23a7ba94f8cd50e19bfd0136cfd2f2c 582 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 89 111 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site Theos_1836 f23a7ba94f8cd50e19bfd0136cfd2f2c 582 SUPERFAMILY SSF53850 35 568 9.59E-108 T 14-10-2018 Theos_1836 f23a7ba94f8cd50e19bfd0136cfd2f2c 582 Gene3D G3DSA:3.40.190.10 17 323 3.2E-59 T 14-10-2018 Theos_1836 f23a7ba94f8cd50e19bfd0136cfd2f2c 582 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 477 6.3E-77 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain Theos_1836 f23a7ba94f8cd50e19bfd0136cfd2f2c 582 Gene3D G3DSA:3.10.105.10 324 546 1.7E-37 T 14-10-2018 Theos_1836 f23a7ba94f8cd50e19bfd0136cfd2f2c 582 PIRSF PIRSF002741 1 571 4.6E-72 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Theos_1734 9b9fb1e0ae17655e25d28c9ad4c22177 143 SUPERFAMILY SSF55239 1 140 1.13E-44 T 14-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1734 9b9fb1e0ae17655e25d28c9ad4c22177 143 SMART SM00961 4 103 5.7E-42 T 14-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1734 9b9fb1e0ae17655e25d28c9ad4c22177 143 Pfam PF00101 Ribulose bisphosphate carboxylase, small chain 5 103 1.6E-37 T 14-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_1734 9b9fb1e0ae17655e25d28c9ad4c22177 143 Gene3D G3DSA:3.30.190.10 1 140 9.6E-50 T 14-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 Theos_0808 e5eacc980080ec866a0902d446d6a16a 485 Pfam PF03023 MviN-like protein 29 441 1.9E-64 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Theos_0808 e5eacc980080ec866a0902d446d6a16a 485 PRINTS PR01806 Virulence factor MviN signature 152 173 7.0E-27 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Theos_0808 e5eacc980080ec866a0902d446d6a16a 485 PRINTS PR01806 Virulence factor MviN signature 30 49 7.0E-27 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Theos_0808 e5eacc980080ec866a0902d446d6a16a 485 PRINTS PR01806 Virulence factor MviN signature 245 271 7.0E-27 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Theos_0808 e5eacc980080ec866a0902d446d6a16a 485 PRINTS PR01806 Virulence factor MviN signature 340 359 7.0E-27 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Theos_0808 e5eacc980080ec866a0902d446d6a16a 485 PRINTS PR01806 Virulence factor MviN signature 128 152 7.0E-27 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Theos_0808 e5eacc980080ec866a0902d446d6a16a 485 PRINTS PR01806 Virulence factor MviN signature 391 408 7.0E-27 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Theos_0808 e5eacc980080ec866a0902d446d6a16a 485 PRINTS PR01806 Virulence factor MviN signature 49 65 7.0E-27 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Theos_0808 e5eacc980080ec866a0902d446d6a16a 485 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 475 5.9E-74 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Theos_0897 c4fb2b0cc9fb2428686769200af7e05a 421 SUPERFAMILY SSF50324 2 87 1.83E-8 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Theos_0897 c4fb2b0cc9fb2428686769200af7e05a 421 SUPERFAMILY SSF101478 125 415 1.05E-75 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily Theos_0897 c4fb2b0cc9fb2428686769200af7e05a 421 Gene3D G3DSA:1.10.4080.10 119 421 2.3E-116 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily Theos_0897 c4fb2b0cc9fb2428686769200af7e05a 421 Pfam PF03747 ADP-ribosylglycohydrolase 130 392 2.2E-68 T 14-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 Theos_0990 b0b33ed381c237f6b6cd8c5d88eb12d1 323 Gene3D G3DSA:1.20.1260.10 14 323 2.6E-121 T 14-10-2018 IPR012347 Ferritin-like Theos_0990 b0b33ed381c237f6b6cd8c5d88eb12d1 323 SUPERFAMILY SSF47240 41 284 3.57E-76 T 14-10-2018 IPR009078 Ferritin-like superfamily Theos_0990 b0b33ed381c237f6b6cd8c5d88eb12d1 323 Pfam PF05138 Phenylacetic acid catabolic protein 31 305 4.8E-93 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 Theos_0990 b0b33ed381c237f6b6cd8c5d88eb12d1 323 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 21 309 2.7E-153 T 14-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 Theos_0692 46b03a1bfbbe5b16eef052a1d032eb17 136 Pfam PF00011 Hsp20/alpha crystallin family 38 134 1.2E-20 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Theos_0692 46b03a1bfbbe5b16eef052a1d032eb17 136 Gene3D G3DSA:2.60.40.790 2 134 2.1E-26 T 14-10-2018 IPR008978 HSP20-like chaperone Theos_0692 46b03a1bfbbe5b16eef052a1d032eb17 136 SUPERFAMILY SSF49764 24 133 1.57E-25 T 14-10-2018 IPR008978 HSP20-like chaperone Theos_0421 f553dfad582b7341934a55be0151b2fa 256 SUPERFAMILY SSF51735 5 247 4.25E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0421 f553dfad582b7341934a55be0151b2fa 256 Gene3D G3DSA:3.40.50.720 1 256 1.2E-85 T 14-10-2018 Theos_0421 f553dfad582b7341934a55be0151b2fa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.6E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0421 f553dfad582b7341934a55be0151b2fa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.6E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0421 f553dfad582b7341934a55be0151b2fa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.6E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0421 f553dfad582b7341934a55be0151b2fa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.6E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0421 f553dfad582b7341934a55be0151b2fa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 3.6E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0421 f553dfad582b7341934a55be0151b2fa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 3.6E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0421 f553dfad582b7341934a55be0151b2fa 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0421 f553dfad582b7341934a55be0151b2fa 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 3.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0421 f553dfad582b7341934a55be0151b2fa 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 3.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_0421 f553dfad582b7341934a55be0151b2fa 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 246 2.8E-68 T 14-10-2018 Theos_0421 f553dfad582b7341934a55be0151b2fa 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Theos_0309 58d86c91ace552db27ec1aed8c978a1d 168 Pfam PF14279 HNH endonuclease 86 138 4.2E-17 T 14-10-2018 IPR029471 HNH endonuclease 5 Theos_0309 58d86c91ace552db27ec1aed8c978a1d 168 SMART SM00507 73 124 1.5E-16 T 14-10-2018 IPR003615 HNH nuclease Theos_0309 58d86c91ace552db27ec1aed8c978a1d 168 Gene3D G3DSA:3.30.40.60 59 150 4.0E-24 T 14-10-2018 Theos_0386 2560f976f8bb2796a0d29bc7749d1dc3 345 SMART SM00267 179 345 1.0E-56 T 14-10-2018 IPR000160 GGDEF domain Theos_0386 2560f976f8bb2796a0d29bc7749d1dc3 345 SUPERFAMILY SSF55073 193 343 1.33E-47 T 14-10-2018 IPR029787 Nucleotide cyclase Theos_0386 2560f976f8bb2796a0d29bc7749d1dc3 345 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 187 344 8.1E-50 T 14-10-2018 IPR000160 GGDEF domain Theos_0386 2560f976f8bb2796a0d29bc7749d1dc3 345 Pfam PF00990 Diguanylate cyclase, GGDEF domain 188 341 7.8E-45 T 14-10-2018 IPR000160 GGDEF domain Theos_0386 2560f976f8bb2796a0d29bc7749d1dc3 345 Gene3D G3DSA:3.30.70.270 176 344 1.1E-55 T 14-10-2018 Theos_0196 784215944e13681e3ffcc60e4d44d46f 389 Gene3D G3DSA:3.90.1150.10 31 384 4.3E-158 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0196 784215944e13681e3ffcc60e4d44d46f 389 Gene3D G3DSA:3.40.640.10 70 288 4.3E-158 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0196 784215944e13681e3ffcc60e4d44d46f 389 SUPERFAMILY SSF53383 13 388 2.1E-118 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0196 784215944e13681e3ffcc60e4d44d46f 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 238 251 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Theos_0196 784215944e13681e3ffcc60e4d44d46f 389 Pfam PF00155 Aminotransferase class I and II 39 385 2.9E-76 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Theos_2185 69b1972d3084211c1cc2df7edd118cc5 413 SUPERFAMILY SSF53623 3 276 3.09E-80 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_2185 69b1972d3084211c1cc2df7edd118cc5 413 TIGRFAM TIGR01499 folC: bifunctional protein FolC 18 401 2.6E-94 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 Theos_2185 69b1972d3084211c1cc2df7edd118cc5 413 Gene3D G3DSA:3.90.190.20 280 405 2.0E-20 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_2185 69b1972d3084211c1cc2df7edd118cc5 413 PIRSF PIRSF001563 1 407 3.6E-100 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 Theos_2185 69b1972d3084211c1cc2df7edd118cc5 413 Gene3D G3DSA:3.40.1190.10 2 278 3.1E-82 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_2185 69b1972d3084211c1cc2df7edd118cc5 413 SUPERFAMILY SSF53244 279 404 1.51E-18 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_2185 69b1972d3084211c1cc2df7edd118cc5 413 Pfam PF08245 Mur ligase middle domain 40 256 3.0E-13 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Theos_2240 306f1c7604b135b63b24c9e7afcdf17e 422 Gene3D G3DSA:3.40.1000.10 65 206 3.3E-6 T 14-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Theos_2120 7be648322428539e1ffff1183d9e862c 371 Pfam PF12704 MacB-like periplasmic core domain 19 213 1.8E-6 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Theos_2120 7be648322428539e1ffff1183d9e862c 371 Pfam PF02687 FtsX-like permease family 269 366 2.1E-13 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Theos_2279 2cbac1e49942016c8fb95bcaac88ca16 530 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 8 433 3.5E-115 T 14-10-2018 IPR014061 Conserved hypothetical protein CHP02688 Theos_2279 2cbac1e49942016c8fb95bcaac88ca16 530 Pfam PF13337 Putative ATP-dependent Lon protease 10 438 1.8E-131 T 14-10-2018 IPR014061 Conserved hypothetical protein CHP02688 Theos_2279 2cbac1e49942016c8fb95bcaac88ca16 530 SUPERFAMILY SSF52540 204 395 1.41E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1481 0361e804bbb60ae7bdc8e0ac36a0307a 661 SUPERFAMILY SSF46548 267 373 1.06E-20 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Theos_1481 0361e804bbb60ae7bdc8e0ac36a0307a 661 Pfam PF02754 Cysteine-rich domain 425 511 3.9E-17 T 14-10-2018 IPR004017 Cysteine-rich domain Theos_1481 0361e804bbb60ae7bdc8e0ac36a0307a 661 Pfam PF02754 Cysteine-rich domain 548 635 3.3E-15 T 14-10-2018 IPR004017 Cysteine-rich domain Theos_1481 0361e804bbb60ae7bdc8e0ac36a0307a 661 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 346 357 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Theos_1481 0361e804bbb60ae7bdc8e0ac36a0307a 661 Pfam PF13183 4Fe-4S dicluster domain 281 360 1.2E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_1481 0361e804bbb60ae7bdc8e0ac36a0307a 661 Gene3D G3DSA:1.10.1060.10 247 379 9.8E-18 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 Gene3D G3DSA:3.60.21.10 96 373 2.4E-89 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 SUPERFAMILY SSF55816 374 563 8.89E-27 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 Pfam PF02872 5'-nucleotidase, C-terminal domain 407 518 1.7E-14 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 PRINTS PR01607 Apyrase family signature 311 331 8.7E-11 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 PRINTS PR01607 Apyrase family signature 38 56 8.7E-11 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 PRINTS PR01607 Apyrase family signature 506 525 8.7E-11 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 PRINTS PR01607 Apyrase family signature 264 281 8.7E-11 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 PRINTS PR01607 Apyrase family signature 283 306 8.7E-11 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 Gene3D G3DSA:3.90.780.10 374 573 4.4E-83 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 TIGRFAM TIGR04486 thiosulf_SoxB: thiosulfohydrolase SoxB 2 563 2.3E-213 T 14-10-2018 IPR030998 Thiosulfohydrolase SoxB Theos_1621 8db0df3afd645e97f4d84eebdd8833c9 573 SUPERFAMILY SSF56300 36 369 3.07E-59 T 14-10-2018 Theos_0567 99cd1985ee3b499c4688882e3eb66dba 175 PIRSF PIRSF019345 1 172 3.2E-52 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Theos_0567 99cd1985ee3b499c4688882e3eb66dba 175 Gene3D G3DSA:1.10.10.10 80 169 1.7E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0567 99cd1985ee3b499c4688882e3eb66dba 175 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 165 1.5E-49 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Theos_0567 99cd1985ee3b499c4688882e3eb66dba 175 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 167 5.2E-35 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Theos_0567 99cd1985ee3b499c4688882e3eb66dba 175 SUPERFAMILY SSF46785 2 79 7.07E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0567 99cd1985ee3b499c4688882e3eb66dba 175 Gene3D G3DSA:1.10.10.10 1 79 6.4E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0567 99cd1985ee3b499c4688882e3eb66dba 175 SUPERFAMILY SSF46785 82 156 2.73E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2103 ea409746446b02b5e0bf82b18ae181ef 140 PIRSF PIRSF016498 2 127 9.2E-24 T 14-10-2018 IPR018699 Protein of unknown function DUF2203 Theos_2103 ea409746446b02b5e0bf82b18ae181ef 140 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 4 121 3.6E-33 T 14-10-2018 IPR018699 Protein of unknown function DUF2203 Theos_0830 333431cc8f0b35e469101005996125c5 241 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 5 215 3.4E-71 T 14-10-2018 IPR013412 CRISPR-associated RAMP Csm3 Theos_0830 333431cc8f0b35e469101005996125c5 241 Pfam PF03787 RAMP superfamily 33 213 2.5E-13 T 14-10-2018 IPR005537 CRISPR type III-associated RAMP protein Theos_2318 196b0920f5b8ad594b42b72c21d37a87 403 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 187 4.7E-26 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Theos_2318 196b0920f5b8ad594b42b72c21d37a87 403 Gene3D G3DSA:3.40.1010.10 1 100 3.2E-17 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Theos_2318 196b0920f5b8ad594b42b72c21d37a87 403 Gene3D G3DSA:3.40.50.150 209 403 6.3E-68 T 14-10-2018 Theos_2318 196b0920f5b8ad594b42b72c21d37a87 403 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 199 5.7E-48 T 14-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 Theos_2318 196b0920f5b8ad594b42b72c21d37a87 403 PIRSF PIRSF036428 1 402 1.1E-106 T 14-10-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00860+2.1.1.132 Theos_2318 196b0920f5b8ad594b42b72c21d37a87 403 SUPERFAMILY SSF53335 217 368 6.98E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_2318 196b0920f5b8ad594b42b72c21d37a87 403 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 237 347 3.5E-5 T 14-10-2018 Theos_2318 196b0920f5b8ad594b42b72c21d37a87 403 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 229 350 8.3E-37 T 14-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 Theos_2318 196b0920f5b8ad594b42b72c21d37a87 403 SUPERFAMILY SSF53790 1 201 6.41E-38 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Theos_1986 133acec81b44d706217444cf9728149d 611 Pfam PF02653 Branched-chain amino acid transport system / permease component 228 579 1.7E-31 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_0189 e39ca93300a55c84a256a26b5a8ab842 285 SUPERFAMILY SSF53474 4 273 1.13E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_0189 e39ca93300a55c84a256a26b5a8ab842 285 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 55 66 1.6E-7 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Theos_0189 e39ca93300a55c84a256a26b5a8ab842 285 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 28 36 1.6E-7 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Theos_0189 e39ca93300a55c84a256a26b5a8ab842 285 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 99 113 1.6E-7 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Theos_0189 e39ca93300a55c84a256a26b5a8ab842 285 Gene3D G3DSA:3.40.50.1820 1 277 8.3E-85 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_0189 e39ca93300a55c84a256a26b5a8ab842 285 Pfam PF12697 Alpha/beta hydrolase family 28 267 1.1E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Theos_0966 3bf24da13a5a2d4672c86dd01f4093d4 227 SMART SM00382 32 220 1.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_0966 3bf24da13a5a2d4672c86dd01f4093d4 227 SUPERFAMILY SSF52540 3 224 7.23E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0966 3bf24da13a5a2d4672c86dd01f4093d4 227 Gene3D G3DSA:3.40.50.300 2 227 6.0E-70 T 14-10-2018 Theos_0966 3bf24da13a5a2d4672c86dd01f4093d4 227 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0966 3bf24da13a5a2d4672c86dd01f4093d4 227 Pfam PF00005 ABC transporter 23 172 1.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2330 93590919d7289541a9526b099c769b9f 90 SUPERFAMILY SSF81301 5 79 8.18E-10 T 14-10-2018 Theos_2330 93590919d7289541a9526b099c769b9f 90 Gene3D G3DSA:3.30.460.10 2 89 3.2E-6 T 14-10-2018 Theos_0252 17ae9cbbd7cf30d256be08107c856c1a 78 PRINTS PR01651 Protein-export SecG membrane protein signature 57 78 1.3E-5 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Theos_0252 17ae9cbbd7cf30d256be08107c856c1a 78 PRINTS PR01651 Protein-export SecG membrane protein signature 5 25 1.3E-5 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Theos_0252 17ae9cbbd7cf30d256be08107c856c1a 78 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 1.3E-5 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Theos_0252 17ae9cbbd7cf30d256be08107c856c1a 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 8 75 1.1E-16 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Theos_0252 17ae9cbbd7cf30d256be08107c856c1a 78 Pfam PF03840 Preprotein translocase SecG subunit 11 75 2.6E-14 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Theos_0225 a4e6a0b45ad0d28b6ef24507e9671b8a 424 Gene3D G3DSA:3.65.10.10 8 412 5.0E-139 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Theos_0225 a4e6a0b45ad0d28b6ef24507e9671b8a 424 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 405 4.7E-72 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Theos_0225 a4e6a0b45ad0d28b6ef24507e9671b8a 424 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 3 415 36.518 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_0225 a4e6a0b45ad0d28b6ef24507e9671b8a 424 SUPERFAMILY SSF55205 5 414 4.09E-110 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Theos_0225 a4e6a0b45ad0d28b6ef24507e9671b8a 424 Gene3D G3DSA:3.65.10.10 23 229 5.0E-139 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Theos_0225 a4e6a0b45ad0d28b6ef24507e9671b8a 424 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 5 412 4.9E-141 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Theos_1201 81ad1a325870ffb30b90377b510e1fa6 119 Gene3D G3DSA:3.40.50.2300 4 118 4.6E-8 T 14-10-2018 Theos_1201 81ad1a325870ffb30b90377b510e1fa6 119 SUPERFAMILY SSF52172 9 113 1.26E-7 T 14-10-2018 IPR011006 CheY-like superfamily Theos_0875 5a103d7f696b4e4a4b77c047a505a515 251 Pfam PF00753 Metallo-beta-lactamase superfamily 34 181 4.4E-16 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0875 5a103d7f696b4e4a4b77c047a505a515 251 SUPERFAMILY SSF56281 30 235 3.14E-39 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_0875 5a103d7f696b4e4a4b77c047a505a515 251 Gene3D G3DSA:3.60.15.10 10 203 7.6E-28 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_0875 5a103d7f696b4e4a4b77c047a505a515 251 SMART SM00849 25 181 2.1E-27 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0718 3da1e10e0ae9c77f7d0ac55b6e9ae1f9 244 Gene3D G3DSA:3.60.21.10 1 222 3.1E-19 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_0718 3da1e10e0ae9c77f7d0ac55b6e9ae1f9 244 Pfam PF00149 Calcineurin-like phosphoesterase 1 185 7.2E-9 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Theos_0718 3da1e10e0ae9c77f7d0ac55b6e9ae1f9 244 SUPERFAMILY SSF56300 1 212 1.38E-22 T 14-10-2018 Theos_1629 54d5e93c6d2f9f756343799fa7183085 203 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 28 124 3.8E-14 T 14-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Theos_1629 54d5e93c6d2f9f756343799fa7183085 203 Gene3D G3DSA:3.40.50.10240 4 202 3.0E-35 T 14-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Theos_1629 54d5e93c6d2f9f756343799fa7183085 203 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 199 3.1E-41 T 14-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Theos_1629 54d5e93c6d2f9f756343799fa7183085 203 SUPERFAMILY SSF63999 1 123 1.44E-23 T 14-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Theos_1219 c3a2d3e49030e14e8a356a32170af27f 172 Pfam PF05685 Putative restriction endonuclease 9 165 1.5E-28 T 14-10-2018 IPR008538 Domain of unknown function DUF820 Theos_1219 c3a2d3e49030e14e8a356a32170af27f 172 Gene3D G3DSA:3.90.1570.10 3 160 4.6E-12 T 14-10-2018 Theos_1219 c3a2d3e49030e14e8a356a32170af27f 172 SUPERFAMILY SSF52980 4 168 2.2E-19 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_2375 ef23a583f779cd1c05f93ec23ec6cfe5 167 Pfam PF07452 CHRD domain 32 162 5.7E-19 T 14-10-2018 IPR010895 CHRD Theos_2375 ef23a583f779cd1c05f93ec23ec6cfe5 167 SMART SM00754 28 164 1.7E-8 T 14-10-2018 IPR010895 CHRD Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 SUPERFAMILY SSF53244 323 475 4.88E-34 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 475 28.524 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 323 405 1.3E-17 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 Gene3D G3DSA:3.90.190.20 327 480 3.6E-45 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 Gene3D G3DSA:3.40.1390.10 3 97 3.4E-21 T 14-10-2018 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 Gene3D G3DSA:3.40.1190.10 99 326 1.5E-58 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 Pfam PF08245 Mur ligase middle domain 108 303 4.0E-34 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 18 475 2.3E-123 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 SUPERFAMILY SSF53623 71 337 1.26E-51 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 Pfam PF01225 Mur ligase family, catalytic domain 19 96 1.5E-7 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Theos_1717 c93b0999fdf4c2f5261e01a5a498dfac 486 SUPERFAMILY SSF63418 1 98 4.19E-21 T 14-10-2018 IPR035911 MurE/MurF, N-terminal Theos_1874 61508524a5c1e5a88fddbee4675e72e3 769 Gene3D G3DSA:2.30.120.10 323 391 8.5E-175 T 14-10-2018 Theos_1874 61508524a5c1e5a88fddbee4675e72e3 769 Pfam PF01804 Penicillin amidase 49 758 1.2E-232 T 14-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 Theos_1874 61508524a5c1e5a88fddbee4675e72e3 769 SUPERFAMILY SSF56235 45 759 4.89E-230 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_1874 61508524a5c1e5a88fddbee4675e72e3 769 Gene3D G3DSA:1.10.439.10 26 182 2.6E-61 T 14-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 Theos_1874 61508524a5c1e5a88fddbee4675e72e3 769 Gene3D G3DSA:1.10.1400.10 541 660 8.5E-175 T 14-10-2018 Theos_1874 61508524a5c1e5a88fddbee4675e72e3 769 PIRSF PIRSF001227 7 760 1.2E-202 T 14-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 Theos_1874 61508524a5c1e5a88fddbee4675e72e3 769 Gene3D G3DSA:3.60.20.10 251 748 8.5E-175 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 66 76 - T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 Gene3D G3DSA:2.130.10.30 105 235 3.7E-34 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 114 140 2.4E-6 T 14-10-2018 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 161 190 1.3E-10 T 14-10-2018 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 313 343 3.7E-7 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 32 76 1.0E-6 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 263 310 4.5E-13 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 Gene3D G3DSA:2.130.10.30 236 344 3.1E-32 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 164 174 - T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 SUPERFAMILY SSF50985 107 342 3.92E-53 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 SUPERFAMILY SSF50965 19 98 3.66E-6 T 14-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 250 266 2.3E-13 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 111 124 2.3E-13 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 73 89 2.3E-13 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 130 146 2.3E-13 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 266 280 2.3E-13 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 Theos_1712 34ca21019917d36bbe7a427dc7e440f4 344 Gene3D G3DSA:2.130.10.30 15 104 7.5E-16 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II Theos_1610 5b4995a128dcb3b873dd91f5c8ffccd3 227 Pfam PF01578 Cytochrome C assembly protein 27 174 1.5E-29 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 Theos_1610 5b4995a128dcb3b873dd91f5c8ffccd3 227 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 111 131 5.2E-29 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1610 5b4995a128dcb3b873dd91f5c8ffccd3 227 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 35 52 5.2E-29 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1610 5b4995a128dcb3b873dd91f5c8ffccd3 227 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 52 72 5.2E-29 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1610 5b4995a128dcb3b873dd91f5c8ffccd3 227 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 146 172 5.2E-29 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1610 5b4995a128dcb3b873dd91f5c8ffccd3 227 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 90 110 5.2E-29 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_2349 e511d9841f1aa5c7e4887ef160c5ae3f 127 Pfam PF03061 Thioesterase superfamily 18 91 5.2E-21 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Theos_2349 e511d9841f1aa5c7e4887ef160c5ae3f 127 SUPERFAMILY SSF54637 4 120 2.12E-40 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_2349 e511d9841f1aa5c7e4887ef160c5ae3f 127 Gene3D G3DSA:3.10.129.10 1 127 6.5E-45 T 14-10-2018 Theos_0357 c1ae326e1311bcc20631bc059fc1bca0 185 SUPERFAMILY SSF100950 1 170 5.02E-46 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Theos_0357 c1ae326e1311bcc20631bc059fc1bca0 185 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 166 3.5E-38 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Theos_0357 c1ae326e1311bcc20631bc059fc1bca0 185 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 166 2.2E-29 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Theos_0357 c1ae326e1311bcc20631bc059fc1bca0 185 Gene3D G3DSA:3.40.50.10420 1 178 2.5E-66 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Theos_0357 c1ae326e1311bcc20631bc059fc1bca0 185 PIRSF PIRSF006806 1 169 8.0E-35 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Theos_0752 4f52f007832d693e254de7e1001cc71b 173 Gene3D G3DSA:1.10.3480.10 3 172 4.0E-27 T 14-10-2018 Theos_0752 4f52f007832d693e254de7e1001cc71b 173 Pfam PF02613 Nitrate reductase delta subunit 28 141 8.5E-17 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone Theos_0752 4f52f007832d693e254de7e1001cc71b 173 SUPERFAMILY SSF89155 6 166 4.71E-27 T 14-10-2018 IPR036411 TorD-like superfamily Theos_1369 e3aea796405f5807793602a00542c6bb 318 Pfam PF00762 Ferrochelatase 3 313 5.3E-74 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Theos_1369 e3aea796405f5807793602a00542c6bb 318 Gene3D G3DSA:3.40.50.1400 158 296 7.6E-95 T 14-10-2018 Theos_1369 e3aea796405f5807793602a00542c6bb 318 SUPERFAMILY SSF53800 3 313 2.94E-71 T 14-10-2018 Theos_1369 e3aea796405f5807793602a00542c6bb 318 ProSitePatterns PS00534 Ferrochelatase signature. 186 204 - T 14-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Theos_1369 e3aea796405f5807793602a00542c6bb 318 Gene3D G3DSA:3.40.50.1400 3 311 7.6E-95 T 14-10-2018 Theos_1369 e3aea796405f5807793602a00542c6bb 318 TIGRFAM TIGR00109 hemH: ferrochelatase 2 312 1.2E-59 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Theos_1369 e3aea796405f5807793602a00542c6bb 318 Hamap MF_00323 Ferrochelatase [hemH]. 1 315 26.761 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Theos_0397 d01d214b4f63668f1da5183ef2796852 124 Pfam PF01521 Iron-sulphur cluster biosynthesis 7 107 2.8E-18 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 Theos_0397 d01d214b4f63668f1da5183ef2796852 124 Gene3D G3DSA:2.60.300.12 6 114 2.9E-36 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Theos_0397 d01d214b4f63668f1da5183ef2796852 124 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 93 110 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 Theos_0397 d01d214b4f63668f1da5183ef2796852 124 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 8 111 3.1E-37 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 Theos_0397 d01d214b4f63668f1da5183ef2796852 124 SUPERFAMILY SSF89360 5 98 1.02E-30 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 SUPERFAMILY SSF51735 5 245 6.16E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 Gene3D G3DSA:3.40.50.720 4 246 1.3E-76 T 14-10-2018 Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.6E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.6E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.6E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 182 0.0017 T 14-10-2018 Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 243 3.5E-56 T 14-10-2018 Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.0E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.0E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.0E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.0E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 2.0E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2402 ea3c43f584c2b5684a78f73527acc698 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.0E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_2065 658d25242b667dcc2b90a5030d71fc3a 238 Gene3D G3DSA:3.40.50.880 16 235 4.7E-22 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1828 d6ba816af9b607a9715405b975b80edb 321 Pfam PF01171 PP-loop family 50 221 8.4E-9 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Theos_1828 d6ba816af9b607a9715405b975b80edb 321 SUPERFAMILY SSF52402 25 224 5.29E-41 T 14-10-2018 Theos_1828 d6ba816af9b607a9715405b975b80edb 321 Gene3D G3DSA:3.40.50.620 1 309 1.0E-70 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1828 d6ba816af9b607a9715405b975b80edb 321 PIRSF PIRSF004976 1 302 1.3E-80 T 14-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 Theos_1835 5246acb94d45b038d5d36fdaaae40802 327 SUPERFAMILY SSF161098 91 313 6.32E-11 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1835 5246acb94d45b038d5d36fdaaae40802 327 Gene3D G3DSA:1.10.3720.10 79 326 6.5E-16 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1835 5246acb94d45b038d5d36fdaaae40802 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 326 1.5E-31 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 Pfam PF00512 His Kinase A (phospho-acceptor) domain 621 687 2.4E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 PRINTS PR00344 Bacterial sensor protein C-terminal signature 765 779 1.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 PRINTS PR00344 Bacterial sensor protein C-terminal signature 783 793 1.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 PRINTS PR00344 Bacterial sensor protein C-terminal signature 793 811 1.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 Gene3D G3DSA:1.10.287.130 584 683 3.9E-19 T 14-10-2018 Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 SMART SM00387 730 831 3.7E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 SUPERFAMILY SSF55874 688 831 5.24E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 SMART SM00388 621 688 1.3E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 Gene3D G3DSA:3.30.565.10 684 830 2.5E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 SUPERFAMILY SSF47384 607 686 1.06E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Theos_0591 4211f26b1d4dea9ce60201a2e354aa75 840 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 730 830 7.8E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Gene3D G3DSA:2.40.50.140 376 460 1.0E-28 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SUPERFAMILY SSF50249 277 377 5.97E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 PRINTS PR00681 Ribosomal protein S1 signature 307 326 1.3E-58 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 PRINTS PR00681 Ribosomal protein S1 signature 229 250 1.3E-58 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 PRINTS PR00681 Ribosomal protein S1 signature 101 120 1.3E-58 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 PRINTS PR00681 Ribosomal protein S1 signature 33 51 1.3E-58 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 PRINTS PR00681 Ribosomal protein S1 signature 172 192 1.3E-58 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 PRINTS PR00681 Ribosomal protein S1 signature 143 160 1.3E-58 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 PRINTS PR00681 Ribosomal protein S1 signature 51 65 1.3E-58 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 PRINTS PR00681 Ribosomal protein S1 signature 347 365 1.3E-58 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 PRINTS PR00681 Ribosomal protein S1 signature 125 141 1.3E-58 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Gene3D G3DSA:2.40.50.140 115 192 3.8E-13 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Pfam PF00575 S1 RNA binding domain 291 364 6.8E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Pfam PF00575 S1 RNA binding domain 379 450 1.6E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Pfam PF00575 S1 RNA binding domain 207 277 8.4E-21 T 14-10-2018 IPR003029 S1 domain GO:0003676 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Pfam PF00575 S1 RNA binding domain 31 104 6.4E-12 T 14-10-2018 IPR003029 S1 domain GO:0003676 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Pfam PF00575 S1 RNA binding domain 120 188 8.0E-12 T 14-10-2018 IPR003029 S1 domain GO:0003676 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SUPERFAMILY SSF50249 119 201 3.23E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Gene3D G3DSA:2.40.50.140 193 279 3.6E-28 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Gene3D G3DSA:2.40.50.140 284 375 6.0E-31 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SMART SM00316 120 188 3.0E-14 T 14-10-2018 IPR022967 RNA-binding domain, S1 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SMART SM00316 207 277 2.4E-26 T 14-10-2018 IPR022967 RNA-binding domain, S1 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SMART SM00316 31 104 2.2E-18 T 14-10-2018 IPR022967 RNA-binding domain, S1 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SMART SM00316 292 364 9.1E-28 T 14-10-2018 IPR022967 RNA-binding domain, S1 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SMART SM00316 379 450 6.6E-27 T 14-10-2018 IPR022967 RNA-binding domain, S1 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SUPERFAMILY SSF50249 206 294 4.85E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 Gene3D G3DSA:2.40.50.140 21 114 1.7E-21 T 14-10-2018 Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SUPERFAMILY SSF50249 13 129 2.76E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_1862 ad07e4fbd8cfd36ce0692b96ad452172 534 SUPERFAMILY SSF50249 364 454 8.21E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 SMART SM00028 282 315 78.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 SMART SM00028 133 166 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 SMART SM00028 351 384 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 SMART SM00028 208 241 0.037 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 SMART SM00028 100 130 460.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 SMART SM00028 246 279 44.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 SUPERFAMILY SSF48452 170 346 4.91E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 SUPERFAMILY SSF48452 6 159 2.53E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 Gene3D G3DSA:1.25.40.10 281 447 2.2E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 Gene3D G3DSA:1.25.40.10 206 280 6.6E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0660 37bcfa75d935d2a342cc79ec9ad29874 449 Pfam PF13432 Tetratricopeptide repeat 252 310 3.1E-6 T 14-10-2018 Theos_0953 5d85376e4b1bbc74240b8e6e15c31339 250 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0953 5d85376e4b1bbc74240b8e6e15c31339 250 SUPERFAMILY SSF51351 1 247 1.57E-85 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0953 5d85376e4b1bbc74240b8e6e15c31339 250 Gene3D G3DSA:3.20.20.70 1 250 3.2E-103 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0953 5d85376e4b1bbc74240b8e6e15c31339 250 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 238 1.0E-53 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0953 5d85376e4b1bbc74240b8e6e15c31339 250 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 55.673 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_0953 5d85376e4b1bbc74240b8e6e15c31339 250 Pfam PF00121 Triosephosphate isomerase 5 245 6.8E-87 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Theos_1335 ed0126a1d8e8b542ebdddbf590b0a27a 208 SUPERFAMILY SSF53448 4 195 1.55E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1335 ed0126a1d8e8b542ebdddbf590b0a27a 208 Pfam PF00535 Glycosyl transferase family 2 4 169 4.6E-27 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Theos_1335 ed0126a1d8e8b542ebdddbf590b0a27a 208 Gene3D G3DSA:3.90.550.10 1 207 8.9E-41 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_0453 502121911361c2754d1df57d9ff9effb 193 SUPERFAMILY SSF100950 32 185 5.44E-26 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Theos_0453 502121911361c2754d1df57d9ff9effb 193 Pfam PF02589 LUD domain 93 183 2.7E-14 T 14-10-2018 IPR003741 LUD domain Theos_0453 502121911361c2754d1df57d9ff9effb 193 Gene3D G3DSA:3.40.50.10420 30 186 3.9E-30 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Theos_0243 b175bb5d54c4da282032521b152b24ac 302 Gene3D G3DSA:1.20.1260.130 2 302 6.0E-126 T 14-10-2018 Theos_0243 b175bb5d54c4da282032521b152b24ac 302 SUPERFAMILY SSF47240 1 298 1.25E-98 T 14-10-2018 IPR009078 Ferritin-like superfamily Theos_0243 b175bb5d54c4da282032521b152b24ac 302 Pfam PF05067 Manganese containing catalase 1 300 1.8E-79 T 14-10-2018 IPR007760 Manganese catalase Theos_2305 53a73b6112104554e0b498d384cb6c7e 343 SUPERFAMILY SSF51679 1 337 1.57E-80 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 Theos_2305 53a73b6112104554e0b498d384cb6c7e 343 Gene3D G3DSA:3.20.20.30 1 340 4.1E-89 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 Theos_2305 53a73b6112104554e0b498d384cb6c7e 343 Pfam PF00296 Luciferase-like monooxygenase 20 268 1.6E-47 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Theos_2305 53a73b6112104554e0b498d384cb6c7e 343 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 2 336 1.6E-141 T 14-10-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative Theos_1733 5b3a77b503bada027ec4250073ffa216 292 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 63 195 1.1E-18 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00819 CbxX/CfqX superfamily signature 100 114 5.9E-69 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00819 CbxX/CfqX superfamily signature 22 36 5.9E-69 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00819 CbxX/CfqX superfamily signature 240 252 5.9E-69 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00819 CbxX/CfqX superfamily signature 62 77 5.9E-69 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00819 CbxX/CfqX superfamily signature 114 133 5.9E-69 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00819 CbxX/CfqX superfamily signature 145 157 5.9E-69 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00819 CbxX/CfqX superfamily signature 166 183 5.9E-69 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00819 CbxX/CfqX superfamily signature 183 202 5.9E-69 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 SUPERFAMILY SSF52540 15 280 9.07E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00820 CbxX/CfqX protein signature 17 31 1.1E-42 T 14-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00820 CbxX/CfqX protein signature 133 146 1.1E-42 T 14-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00820 CbxX/CfqX protein signature 247 258 1.1E-42 T 14-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00820 CbxX/CfqX protein signature 271 285 1.1E-42 T 14-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00820 CbxX/CfqX protein signature 76 91 1.1E-42 T 14-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00820 CbxX/CfqX protein signature 35 49 1.1E-42 T 14-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 PRINTS PR00820 CbxX/CfqX protein signature 232 243 1.1E-42 T 14-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 SMART SM00382 59 198 1.9E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1733 5b3a77b503bada027ec4250073ffa216 292 Gene3D G3DSA:1.10.8.60 196 287 1.7E-24 T 14-10-2018 Theos_1733 5b3a77b503bada027ec4250073ffa216 292 Gene3D G3DSA:3.40.50.300 4 195 4.1E-58 T 14-10-2018 Theos_1834 116f5b14755e875491a7743cf215085e 451 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 8 56 1.8E-12 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Theos_1834 116f5b14755e875491a7743cf215085e 451 Gene3D G3DSA:1.10.3720.10 246 450 1.5E-13 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1834 116f5b14755e875491a7743cf215085e 451 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 273 450 6.4E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1834 116f5b14755e875491a7743cf215085e 451 SUPERFAMILY SSF161098 250 432 3.66E-17 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0168 c6bdea9d271352c0231bd9b59eba9895 349 Pfam PF02817 e3 binding domain 5 39 2.4E-13 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Theos_0168 c6bdea9d271352c0231bd9b59eba9895 349 SUPERFAMILY SSF47005 4 43 2.09E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Theos_0168 c6bdea9d271352c0231bd9b59eba9895 349 Gene3D G3DSA:4.10.320.10 5 48 2.0E-15 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Theos_1910 676f16e97a5d263c79a101a3766e3d7b 365 Gene3D G3DSA:2.30.30.280 214 276 4.2E-16 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Theos_1910 676f16e97a5d263c79a101a3766e3d7b 365 SUPERFAMILY SSF52402 3 245 1.87E-49 T 14-10-2018 Theos_1910 676f16e97a5d263c79a101a3766e3d7b 365 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 3 349 39.667 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Theos_1910 676f16e97a5d263c79a101a3766e3d7b 365 Gene3D G3DSA:3.40.50.620 1 212 1.3E-75 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1910 676f16e97a5d263c79a101a3766e3d7b 365 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 5 348 4.3E-97 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Theos_1910 676f16e97a5d263c79a101a3766e3d7b 365 Pfam PF03054 tRNA methyl transferase 5 348 3.6E-115 T 14-10-2018 Theos_1910 676f16e97a5d263c79a101a3766e3d7b 365 Gene3D G3DSA:2.40.30.10 277 353 2.7E-17 T 14-10-2018 Theos_0187 7279c69b19e0dcebef98ce2bb1a49b60 192 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 183 3.6E-34 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal Theos_0187 7279c69b19e0dcebef98ce2bb1a49b60 192 Gene3D G3DSA:3.40.225.10 1 192 5.8E-69 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Theos_0187 7279c69b19e0dcebef98ce2bb1a49b60 192 SUPERFAMILY SSF53639 11 191 2.55E-37 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Theos_0187 7279c69b19e0dcebef98ce2bb1a49b60 192 SMART SM01007 7 184 4.0E-40 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 SUPERFAMILY SSF81296 292 405 2.17E-29 T 14-10-2018 IPR014756 Immunoglobulin E-set Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 Gene3D G3DSA:3.90.420.10 27 272 5.1E-59 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 SUPERFAMILY SSF56524 30 261 1.01E-53 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 291 402 5.4E-12 T 14-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 Pfam PF00174 Oxidoreductase molybdopterin binding domain 91 249 1.7E-42 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 148 163 3.1E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 231 244 3.1E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 215 228 3.1E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 327 339 3.1E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 66 82 3.1E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 198 214 3.1E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 288 300 3.1E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 Theos_0519 e58187ec872f8d43e17c94d00a807f3f 406 Gene3D G3DSA:2.60.40.650 290 406 9.0E-30 T 14-10-2018 Theos_2475 24b34a7f42a989fde16da3c1d1944c20 259 SUPERFAMILY SSF55781 59 247 1.18E-52 T 14-10-2018 Theos_2475 24b34a7f42a989fde16da3c1d1944c20 259 SMART SM00346 2 91 3.9E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Theos_2475 24b34a7f42a989fde16da3c1d1944c20 259 Pfam PF09339 IclR helix-turn-helix domain 5 53 2.3E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Theos_2475 24b34a7f42a989fde16da3c1d1944c20 259 Gene3D G3DSA:1.10.10.10 2 71 2.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2475 24b34a7f42a989fde16da3c1d1944c20 259 SUPERFAMILY SSF46785 3 73 7.08E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2475 24b34a7f42a989fde16da3c1d1944c20 259 Gene3D G3DSA:3.30.450.40 72 253 4.4E-60 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_2475 24b34a7f42a989fde16da3c1d1944c20 259 Pfam PF01614 Bacterial transcriptional regulator 122 242 2.1E-36 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal Theos_0334 03aed8a5d6951b16d67fe44073cdc475 82 ProDom PD058861 TRANSCRIPTIONAL ABRB FAMILY REGULATOR AF0476 REGULATOR 5 32 0.008 T 14-10-2018 Theos_0334 03aed8a5d6951b16d67fe44073cdc475 82 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 45 1.9E-15 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Theos_0334 03aed8a5d6951b16d67fe44073cdc475 82 SMART SM00966 5 50 3.4E-13 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Theos_0334 03aed8a5d6951b16d67fe44073cdc475 82 SUPERFAMILY SSF89447 5 44 4.36E-12 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Theos_0334 03aed8a5d6951b16d67fe44073cdc475 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 45 8.5E-13 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Theos_0334 03aed8a5d6951b16d67fe44073cdc475 82 Gene3D G3DSA:2.10.260.10 6 43 4.5E-13 T 14-10-2018 Theos_2100 fdf0196fa53a194697890e36349820fd 367 Pfam PF00676 Dehydrogenase E1 component 43 340 4.7E-83 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 Theos_2100 fdf0196fa53a194697890e36349820fd 367 SUPERFAMILY SSF52518 32 365 1.05E-105 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Theos_2100 fdf0196fa53a194697890e36349820fd 367 Gene3D G3DSA:3.40.50.970 1 367 6.7E-125 T 14-10-2018 Theos_1089 c0b8bba4c092d1b02e42b296fe06f8c6 369 SUPERFAMILY SSF161098 56 179 2.45E-19 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1089 c0b8bba4c092d1b02e42b296fe06f8c6 369 SUPERFAMILY SSF161098 173 355 3.4E-28 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1089 c0b8bba4c092d1b02e42b296fe06f8c6 369 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 356 7.8E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2546 1bcd98a4c96c1a7b359b1ad59a99c888 318 SUPERFAMILY SSF56349 148 309 6.77E-16 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Theos_2546 1bcd98a4c96c1a7b359b1ad59a99c888 318 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 57 126 1.7E-5 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Theos_2546 1bcd98a4c96c1a7b359b1ad59a99c888 318 Pfam PF00589 Phage integrase family 149 312 2.1E-7 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Theos_2546 1bcd98a4c96c1a7b359b1ad59a99c888 318 Gene3D G3DSA:1.10.443.10 141 315 2.3E-10 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Theos_0408 b1a2c3afc1bae469bd205bf64246cca9 250 SUPERFAMILY SSF90257 29 147 4.97E-5 T 14-10-2018 Theos_0408 b1a2c3afc1bae469bd205bf64246cca9 250 Pfam PF02591 C4-type zinc ribbon domain 215 246 9.4E-9 T 14-10-2018 IPR003743 C4-type zinc ribbon domain Theos_0896 83ed0f219bfb7e6e6b980c73d56be95b 344 SUPERFAMILY SSF111337 1 344 2.62E-127 T 14-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Theos_0896 83ed0f219bfb7e6e6b980c73d56be95b 344 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 344 43.993 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Theos_0896 83ed0f219bfb7e6e6b980c73d56be95b 344 Gene3D G3DSA:3.40.1780.10 14 343 1.2E-114 T 14-10-2018 Theos_0896 83ed0f219bfb7e6e6b980c73d56be95b 344 Pfam PF02547 Queuosine biosynthesis protein 4 343 3.0E-127 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Theos_0896 83ed0f219bfb7e6e6b980c73d56be95b 344 Gene3D G3DSA:2.40.10.240 65 167 1.2E-114 T 14-10-2018 Theos_0896 83ed0f219bfb7e6e6b980c73d56be95b 344 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 344 2.2E-106 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Theos_0240 a0ffdb0e138f8b80d924024e87086304 191 Gene3D G3DSA:3.40.1280.10 1 191 3.1E-76 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Theos_0240 a0ffdb0e138f8b80d924024e87086304 191 Pfam PF00588 SpoU rRNA Methylase family 20 159 1.1E-34 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Theos_0240 a0ffdb0e138f8b80d924024e87086304 191 SUPERFAMILY SSF75217 3 186 4.64E-52 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Theos_0240 a0ffdb0e138f8b80d924024e87086304 191 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 2 191 35.613 T 14-10-2018 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 Theos_0362 5c54ab01fec3fab87840736ff4a69353 252 SUPERFAMILY SSF56300 17 241 1.74E-41 T 14-10-2018 Theos_0362 5c54ab01fec3fab87840736ff4a69353 252 Gene3D G3DSA:3.60.21.10 118 245 5.9E-22 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_0362 5c54ab01fec3fab87840736ff4a69353 252 Gene3D G3DSA:3.60.21.10 13 117 9.1E-6 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_0362 5c54ab01fec3fab87840736ff4a69353 252 Pfam PF00149 Calcineurin-like phosphoesterase 17 184 2.2E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Theos_1912 a0cf6773479f730ed73b63c6ba45c752 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 296 7.4E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1912 a0cf6773479f730ed73b63c6ba45c752 300 Gene3D G3DSA:1.10.3720.10 70 298 1.1E-35 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1912 a0cf6773479f730ed73b63c6ba45c752 300 SUPERFAMILY SSF161098 16 290 1.44E-36 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1912 a0cf6773479f730ed73b63c6ba45c752 300 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 17 295 2.9E-72 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 Theos_2146 ae7c5da0b6a2496b31c0a5c07a62641e 251 Gene3D G3DSA:1.10.3720.10 1 238 2.5E-56 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2146 ae7c5da0b6a2496b31c0a5c07a62641e 251 SUPERFAMILY SSF161098 8 251 1.31E-64 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2146 ae7c5da0b6a2496b31c0a5c07a62641e 251 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 53 243 1.0E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_2175 47269655b54cb7d7fbcede2dfe0892e9 211 Gene3D G3DSA:2.50.20.10 12 211 9.6E-56 T 14-10-2018 Theos_1907 4d499a8d383f3d2dbf7a92b043a0bacf 147 SUPERFAMILY SSF46785 8 144 4.92E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1907 4d499a8d383f3d2dbf7a92b043a0bacf 147 Gene3D G3DSA:3.30.1490.190 89 147 8.5E-13 T 14-10-2018 Theos_1907 4d499a8d383f3d2dbf7a92b043a0bacf 147 Pfam PF01475 Ferric uptake regulator family 17 113 8.2E-25 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Theos_1907 4d499a8d383f3d2dbf7a92b043a0bacf 147 Gene3D G3DSA:1.10.10.10 3 87 8.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0080 00b7c98ae81d08864b8c71cecb936e98 155 Pfam PF04073 Aminoacyl-tRNA editing domain 29 144 5.4E-29 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Theos_0080 00b7c98ae81d08864b8c71cecb936e98 155 SUPERFAMILY SSF55826 9 152 4.32E-34 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Theos_0080 00b7c98ae81d08864b8c71cecb936e98 155 Gene3D G3DSA:3.90.960.10 2 154 4.9E-49 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Theos_1394 e98d8fb5087bd7bb623da3f96a688984 377 SUPERFAMILY SSF50331 236 365 8.02E-31 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Theos_1394 e98d8fb5087bd7bb623da3f96a688984 377 SMART SM00382 28 211 5.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1394 e98d8fb5087bd7bb623da3f96a688984 377 Gene3D G3DSA:3.40.50.300 1 238 6.4E-75 T 14-10-2018 Theos_1394 e98d8fb5087bd7bb623da3f96a688984 377 Gene3D G3DSA:2.40.50.100 239 364 2.2E-28 T 14-10-2018 Theos_1394 e98d8fb5087bd7bb623da3f96a688984 377 SUPERFAMILY SSF52540 4 243 2.46E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1394 e98d8fb5087bd7bb623da3f96a688984 377 Pfam PF00005 ABC transporter 20 161 3.6E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1394 e98d8fb5087bd7bb623da3f96a688984 377 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1394 e98d8fb5087bd7bb623da3f96a688984 377 Gene3D G3DSA:2.40.50.140 285 350 2.2E-28 T 14-10-2018 Theos_1394 e98d8fb5087bd7bb623da3f96a688984 377 Pfam PF03459 TOBE domain 301 355 2.2E-11 T 14-10-2018 IPR005116 Transport-associated OB, type 1 Theos_0057 224eeeb466180606a2be8a5982ab79f6 249 SUPERFAMILY SSF54909 6 248 2.6E-79 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Theos_0057 224eeeb466180606a2be8a5982ab79f6 249 Gene3D G3DSA:3.30.70.1030 1 123 2.3E-39 T 14-10-2018 Theos_0057 224eeeb466180606a2be8a5982ab79f6 249 Gene3D G3DSA:3.30.70.1100 124 249 1.2E-53 T 14-10-2018 Theos_0057 224eeeb466180606a2be8a5982ab79f6 249 Pfam PF06778 Chlorite dismutase 37 237 9.7E-64 T 14-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase Theos_0725 83753a242f536bd662d52ef0a601a16b 234 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 58 224 2.7E-34 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 Theos_0725 83753a242f536bd662d52ef0a601a16b 234 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 59 218 2.5E-50 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 Theos_0973 9f5df580a98405ee40a3ed237ea9da03 147 Pfam PF01613 Flavin reductase like domain 11 146 8.4E-32 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Theos_0973 9f5df580a98405ee40a3ed237ea9da03 147 SUPERFAMILY SSF50475 2 145 2.5E-37 T 14-10-2018 Theos_0973 9f5df580a98405ee40a3ed237ea9da03 147 SMART SM00903 10 145 4.0E-44 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Theos_0973 9f5df580a98405ee40a3ed237ea9da03 147 Gene3D G3DSA:2.30.110.10 3 147 1.2E-43 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Theos_1716 f9a153d16b481f878de28513067d3c08 199 SUPERFAMILY SSF52540 1 197 2.0E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1716 f9a153d16b481f878de28513067d3c08 199 Pfam PF01712 Deoxynucleoside kinase 3 196 6.4E-51 T 14-10-2018 IPR031314 Deoxynucleoside kinase domain Theos_1716 f9a153d16b481f878de28513067d3c08 199 Gene3D G3DSA:3.40.50.300 1 199 1.0E-54 T 14-10-2018 Theos_1716 f9a153d16b481f878de28513067d3c08 199 PIRSF PIRSF000705 1 199 1.9E-58 T 14-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 Theos_0827 9faaeccbf6d9ada73ecf2eaae8a4dfd5 389 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 102 122 2.5E-5 T 14-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site Theos_0827 9faaeccbf6d9ada73ecf2eaae8a4dfd5 389 SUPERFAMILY SSF160980 18 364 1.44E-10 T 14-10-2018 Theos_0827 9faaeccbf6d9ada73ecf2eaae8a4dfd5 389 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 10 362 3.5E-61 T 14-10-2018 IPR019016 CRISPR-associated DxTHG protein Theos_1664 07c0ad743f1be2d439ccf66a0d694643 306 Pfam PF00005 ABC transporter 19 161 1.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1664 07c0ad743f1be2d439ccf66a0d694643 306 Gene3D G3DSA:3.40.50.300 1 225 4.0E-67 T 14-10-2018 Theos_1664 07c0ad743f1be2d439ccf66a0d694643 306 SMART SM00382 27 227 5.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1664 07c0ad743f1be2d439ccf66a0d694643 306 SUPERFAMILY SSF52540 3 223 4.66E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0138 913acc1303fbfbce686745033993d1fb 171 Gene3D G3DSA:3.40.50.450 1 171 1.2E-52 T 14-10-2018 Theos_0138 913acc1303fbfbce686745033993d1fb 171 Pfam PF03641 Possible lysine decarboxylase 45 140 7.2E-11 T 14-10-2018 IPR031100 LOG family Theos_0138 913acc1303fbfbce686745033993d1fb 171 SUPERFAMILY SSF102405 1 168 3.97E-30 T 14-10-2018 Theos_1622 3d38a3585c3779cc6185bbdb9547925f 190 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 97 176 9.1E-23 T 14-10-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX Theos_1622 3d38a3585c3779cc6185bbdb9547925f 190 PIRSF PIRSF024608 1 183 1.8E-72 T 14-10-2018 IPR016823 Sulfur oxidation c-type cytochrome SoxX, type II Theos_1622 3d38a3585c3779cc6185bbdb9547925f 190 Gene3D G3DSA:1.10.760.10 19 183 1.9E-44 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1622 3d38a3585c3779cc6185bbdb9547925f 190 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 88 174 6.9E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1622 3d38a3585c3779cc6185bbdb9547925f 190 SUPERFAMILY SSF46626 4 175 4.31E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1648 b5c8d6c19b85286e9cdef7c4a23a61b9 417 Gene3D G3DSA:3.40.190.10 38 370 7.3E-83 T 14-10-2018 Theos_1648 b5c8d6c19b85286e9cdef7c4a23a61b9 417 Pfam PF13416 Bacterial extracellular solute-binding protein 54 349 7.5E-44 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_1648 b5c8d6c19b85286e9cdef7c4a23a61b9 417 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 142 159 - T 14-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 Theos_1648 b5c8d6c19b85286e9cdef7c4a23a61b9 417 Gene3D G3DSA:3.40.190.10 147 407 7.3E-83 T 14-10-2018 Theos_1648 b5c8d6c19b85286e9cdef7c4a23a61b9 417 SUPERFAMILY SSF53850 38 409 2.98E-70 T 14-10-2018 Theos_2025 237424917430729d9a136377cd0df066 104 Pfam PF04134 Protein of unknown function, DUF393 5 102 1.4E-12 T 14-10-2018 IPR007263 Protein of unknown function DUF393 Theos_0093 d97a6cd7b0ec20df20a0260ce81d25b0 169 Gene3D G3DSA:2.60.40.3700 17 167 1.5E-36 T 14-10-2018 Theos_1692 28bd8385cb87562f927377e481af7f7c 663 SUPERFAMILY SSF52540 248 418 2.19E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0110 20a873300b9dd491811a4b4a06bf07a7 100 Gene3D G3DSA:2.102.10.10 1 100 5.8E-30 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Theos_0110 20a873300b9dd491811a4b4a06bf07a7 100 Pfam PF00355 Rieske [2Fe-2S] domain 2 88 3.3E-15 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Theos_0110 20a873300b9dd491811a4b4a06bf07a7 100 SUPERFAMILY SSF50022 1 99 3.67E-27 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Theos_0023 ae79c063a1600f3ba7e55504190fa73c 263 Pfam PF02535 ZIP Zinc transporter 113 258 4.7E-16 T 14-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 167 438 2.1E-22 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 103 123 5.0E-47 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 61 76 5.0E-47 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 147 173 5.0E-47 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 31 56 5.0E-47 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 5.0E-47 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 82 102 5.0E-47 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 Gene3D G3DSA:3.90.380.10 28 438 2.9E-158 T 14-10-2018 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 SUPERFAMILY SSF55961 164 439 3.45E-58 T 14-10-2018 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 Gene3D G3DSA:2.102.10.10 46 171 2.9E-158 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 SUPERFAMILY SSF50022 19 162 8.51E-51 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 Pfam PF00355 Rieske [2Fe-2S] domain 46 130 8.8E-23 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Theos_2219 ba2ea6caa58e0c73738fa3784cd07d54 440 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 89 112 - T 14-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 Theos_0638 e3290ee693509d21939d91f8fdf76f38 475 Pfam PF00128 Alpha amylase, catalytic domain 47 360 2.1E-70 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Theos_0638 e3290ee693509d21939d91f8fdf76f38 475 SUPERFAMILY SSF51445 2 394 3.41E-104 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily Theos_0638 e3290ee693509d21939d91f8fdf76f38 475 SMART SM00642 11 388 9.8E-109 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Theos_0638 e3290ee693509d21939d91f8fdf76f38 475 Gene3D G3DSA:2.60.40.1180 391 475 2.7E-46 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta Theos_0638 e3290ee693509d21939d91f8fdf76f38 475 Gene3D G3DSA:3.20.20.80 1 390 3.4E-161 T 14-10-2018 Theos_0638 e3290ee693509d21939d91f8fdf76f38 475 SUPERFAMILY SSF51011 399 473 3.06E-5 T 14-10-2018 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 Gene3D G3DSA:3.90.226.10 1 315 1.1E-121 T 14-10-2018 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 3 145 1.3E-62 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 SUPERFAMILY SSF52096 4 313 3.27E-96 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 2 313 49.751 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 313 7.9E-135 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 131 147 1.4E-44 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 150 163 1.4E-44 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 194 203 1.4E-44 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 166 179 1.4E-44 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 110 128 1.4E-44 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_0270 7c875b1f575314c58f88dc76caae17e2 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 85 96 1.4E-44 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Theos_2269 dca0eb33a7f8041c66f8f82dc128927f 492 Pfam PF09967 VWA-like domain (DUF2201) 365 490 1.6E-17 T 14-10-2018 IPR018698 VWA-like domain Theos_2269 dca0eb33a7f8041c66f8f82dc128927f 492 Pfam PF13203 Putative metallopeptidase domain 9 336 3.2E-32 T 14-10-2018 IPR025154 Putative metallopeptidase domain Theos_1057 1a419ebde72926bdccc95b54bad35235 221 Pfam PF00034 Cytochrome c 115 205 1.4E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1057 1a419ebde72926bdccc95b54bad35235 221 Gene3D G3DSA:1.10.760.10 99 219 1.3E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1057 1a419ebde72926bdccc95b54bad35235 221 SUPERFAMILY SSF46626 113 208 2.54E-13 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1178 c465fdaf65243c5dc6345c66e340840d 282 Pfam PF01734 Patatin-like phospholipase 6 175 1.7E-24 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Theos_1178 c465fdaf65243c5dc6345c66e340840d 282 Gene3D G3DSA:3.40.1090.10 2 85 4.1E-18 T 14-10-2018 Theos_1178 c465fdaf65243c5dc6345c66e340840d 282 Gene3D G3DSA:3.40.1090.10 96 196 5.7E-15 T 14-10-2018 Theos_1178 c465fdaf65243c5dc6345c66e340840d 282 SUPERFAMILY SSF52151 4 258 5.23E-47 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Theos_0549 c74aacceaa8fbffe651fc130ccbd1b6c 349 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 331 47.371 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 Theos_0549 c74aacceaa8fbffe651fc130ccbd1b6c 349 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 83 102 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 Theos_0549 c74aacceaa8fbffe651fc130ccbd1b6c 349 SUPERFAMILY SSF51395 5 346 1.22E-94 T 14-10-2018 Theos_0549 c74aacceaa8fbffe651fc130ccbd1b6c 349 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 4 345 1.2E-112 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 Theos_0549 c74aacceaa8fbffe651fc130ccbd1b6c 349 PIRSF PIRSF000164 12 347 3.6E-93 T 14-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Theos_0549 c74aacceaa8fbffe651fc130ccbd1b6c 349 Gene3D G3DSA:3.20.20.70 2 348 1.9E-116 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0549 c74aacceaa8fbffe651fc130ccbd1b6c 349 Pfam PF01180 Dihydroorotate dehydrogenase 48 335 6.1E-79 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Theos_1654 584c0969465486273a10e9118d95e418 252 SUPERFAMILY SSF51556 2 250 4.54E-65 T 14-10-2018 IPR032466 Metal-dependent hydrolase Theos_1654 584c0969465486273a10e9118d95e418 252 Pfam PF01026 TatD related DNase 2 248 2.4E-57 T 14-10-2018 IPR001130 TatD family GO:0016788 Theos_1654 584c0969465486273a10e9118d95e418 252 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 185 201 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 Theos_1654 584c0969465486273a10e9118d95e418 252 Gene3D G3DSA:3.20.20.140 1 250 4.3E-68 T 14-10-2018 Theos_1654 584c0969465486273a10e9118d95e418 252 PIRSF PIRSF005902 1 252 4.6E-54 T 14-10-2018 IPR001130 TatD family GO:0016788 Theos_0800 8fa5d56d7c9f32f78cb815d4e0515d28 329 Gene3D G3DSA:1.20.120.420 5 129 2.3E-30 T 14-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Theos_0800 8fa5d56d7c9f32f78cb815d4e0515d28 329 Gene3D G3DSA:3.40.50.10470 132 328 3.7E-65 T 14-10-2018 Theos_0800 8fa5d56d7c9f32f78cb815d4e0515d28 329 SUPERFAMILY SSF100950 11 320 8.29E-106 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Theos_0800 8fa5d56d7c9f32f78cb815d4e0515d28 329 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 2 326 39.228 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Theos_0800 8fa5d56d7c9f32f78cb815d4e0515d28 329 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 12 315 2.4E-117 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Theos_0800 8fa5d56d7c9f32f78cb815d4e0515d28 329 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 33 316 2.5E-94 T 14-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Theos_0800 8fa5d56d7c9f32f78cb815d4e0515d28 329 Pfam PF01008 Initiation factor 2 subunit family 72 316 3.5E-63 T 14-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 Theos_1675 c086f80951a9c4af923dc07608257645 183 Gene3D G3DSA:1.10.490.10 7 159 5.7E-31 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Theos_1675 c086f80951a9c4af923dc07608257645 183 Pfam PF11563 Protoglobin 7 157 2.9E-25 T 14-10-2018 Theos_1675 c086f80951a9c4af923dc07608257645 183 SUPERFAMILY SSF46458 7 149 1.22E-27 T 14-10-2018 IPR009050 Globin-like superfamily Theos_2403 c04bf883d2c8ba7c8b8d0bac9b5257bb 308 SUPERFAMILY SSF53613 1 300 6.55E-83 T 14-10-2018 IPR029056 Ribokinase-like Theos_2403 c04bf883d2c8ba7c8b8d0bac9b5257bb 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Theos_2403 c04bf883d2c8ba7c8b8d0bac9b5257bb 308 PRINTS PR00990 Ribokinase signature 215 226 9.0E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Theos_2403 c04bf883d2c8ba7c8b8d0bac9b5257bb 308 PRINTS PR00990 Ribokinase signature 182 197 9.0E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Theos_2403 c04bf883d2c8ba7c8b8d0bac9b5257bb 308 PRINTS PR00990 Ribokinase signature 28 47 9.0E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Theos_2403 c04bf883d2c8ba7c8b8d0bac9b5257bb 308 Gene3D G3DSA:3.40.1190.20 1 304 1.7E-110 T 14-10-2018 IPR029056 Ribokinase-like Theos_2403 c04bf883d2c8ba7c8b8d0bac9b5257bb 308 Pfam PF00294 pfkB family carbohydrate kinase 1 288 1.6E-43 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB Theos_0552 3b5a528eae2c793a50d59f200ed73f0d 165 Gene3D G3DSA:3.40.50.1010 12 144 1.7E-7 T 14-10-2018 Theos_0552 3b5a528eae2c793a50d59f200ed73f0d 165 SUPERFAMILY SSF88723 12 148 1.37E-11 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_0552 3b5a528eae2c793a50d59f200ed73f0d 165 Pfam PF01850 PIN domain 13 143 9.9E-9 T 14-10-2018 IPR002716 PIN domain Theos_0069 4d8233ae0d8860c52249194f98205edb 295 SUPERFAMILY SSF53474 38 225 9.93E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_0069 4d8233ae0d8860c52249194f98205edb 295 Gene3D G3DSA:3.40.50.1820 36 241 5.6E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1797 dea780d929e0ca3c0e252b513091c8de 237 SUPERFAMILY SSF142823 13 226 2.22E-54 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Theos_1797 dea780d929e0ca3c0e252b513091c8de 237 Gene3D G3DSA:3.90.1560.10 1 237 2.7E-81 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Theos_1797 dea780d929e0ca3c0e252b513091c8de 237 Pfam PF04029 2-phosphosulpholactate phosphatase 12 225 1.2E-67 T 14-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Theos_1052 c0419d5abba39c7556da8d15305a657e 547 Pfam PF02239 Cytochrome D1 heme domain 151 542 2.7E-111 T 14-10-2018 Theos_1052 c0419d5abba39c7556da8d15305a657e 547 Gene3D G3DSA:2.140.10.20 125 547 2.8E-166 T 14-10-2018 IPR003143 Cytochrome cd1-nitrite reductase, C-terminal domain superfamily Theos_1052 c0419d5abba39c7556da8d15305a657e 547 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 42 114 7.7E-10 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1052 c0419d5abba39c7556da8d15305a657e 547 SUPERFAMILY SSF46626 19 122 1.33E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1052 c0419d5abba39c7556da8d15305a657e 547 Gene3D G3DSA:1.10.760.10 29 122 1.2E-29 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1052 c0419d5abba39c7556da8d15305a657e 547 SUPERFAMILY SSF51004 126 547 3.4E-97 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily Theos_0289 c1b242a4f2c6ea5852aaae0f63ed13b6 182 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 4 182 43.834 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0289 c1b242a4f2c6ea5852aaae0f63ed13b6 182 Pfam PF00281 Ribosomal protein L5 27 83 3.0E-26 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0289 c1b242a4f2c6ea5852aaae0f63ed13b6 182 PIRSF PIRSF002161 3 182 6.0E-65 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0289 c1b242a4f2c6ea5852aaae0f63ed13b6 182 SUPERFAMILY SSF55282 7 182 3.3E-75 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0289 c1b242a4f2c6ea5852aaae0f63ed13b6 182 Gene3D G3DSA:3.30.1440.10 1 182 6.7E-84 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0289 c1b242a4f2c6ea5852aaae0f63ed13b6 182 Pfam PF00673 ribosomal L5P family C-terminus 87 180 1.6E-39 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0289 c1b242a4f2c6ea5852aaae0f63ed13b6 182 ProSitePatterns PS00358 Ribosomal protein L5 signature. 60 76 - T 14-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Theos_0467 290456b41bc74809797d5b64f7161b75 419 Pfam PF01943 Polysaccharide biosynthesis protein 14 277 3.9E-36 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 Theos_2162 25680131a44d01cb5b5721ac4c29187f 291 Gene3D G3DSA:1.10.3720.10 49 288 2.2E-73 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2162 25680131a44d01cb5b5721ac4c29187f 291 SUPERFAMILY SSF161098 53 280 1.44E-64 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2162 25680131a44d01cb5b5721ac4c29187f 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 281 5.2E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0184 3d1f103a51f7a7056288e1cb2f64ebe1 218 Gene3D G3DSA:3.10.290.10 132 183 2.3E-5 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Theos_0184 3d1f103a51f7a7056288e1cb2f64ebe1 218 SUPERFAMILY SSF55174 131 203 2.94E-7 T 14-10-2018 Theos_0184 3d1f103a51f7a7056288e1cb2f64ebe1 218 Gene3D G3DSA:3.30.1370.160 5 61 1.1E-5 T 14-10-2018 Theos_1584 7eb1568337d38f1cc1088fb7ffec6efb 545 SUPERFAMILY SSF51905 2 542 1.41E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1584 7eb1568337d38f1cc1088fb7ffec6efb 545 Pfam PF00890 FAD binding domain 4 526 1.1E-99 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Theos_1584 7eb1568337d38f1cc1088fb7ffec6efb 545 PIRSF PIRSF036654 1 544 6.7E-246 T 14-10-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 Theos_1584 7eb1568337d38f1cc1088fb7ffec6efb 545 Gene3D G3DSA:3.50.50.60 464 543 1.2E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1584 7eb1568337d38f1cc1088fb7ffec6efb 545 Gene3D G3DSA:3.50.50.60 1 288 8.3E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0633 417494e08c28cd8167f7501e88cebd57 269 Gene3D G3DSA:3.40.190.10 77 169 7.0E-112 T 14-10-2018 Theos_0633 417494e08c28cd8167f7501e88cebd57 269 SUPERFAMILY SSF53850 2 260 6.27E-85 T 14-10-2018 Theos_0633 417494e08c28cd8167f7501e88cebd57 269 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 1 261 42.19 T 14-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 Theos_0633 417494e08c28cd8167f7501e88cebd57 269 Gene3D G3DSA:3.40.190.10 3 256 7.0E-112 T 14-10-2018 Theos_0633 417494e08c28cd8167f7501e88cebd57 269 Pfam PF02621 Menaquinone biosynthesis 1 255 8.8E-90 T 14-10-2018 IPR003773 Menaquinone biosynthesis enzyme Theos_1304 2d32df2f7094f8660c9496430e17be2d 196 SMART SM00530 12 70 5.1E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Theos_1304 2d32df2f7094f8660c9496430e17be2d 196 Gene3D G3DSA:1.10.260.40 2 70 1.5E-9 T 14-10-2018 Theos_1304 2d32df2f7094f8660c9496430e17be2d 196 Pfam PF13560 Helix-turn-helix domain 10 71 6.0E-10 T 14-10-2018 Theos_1304 2d32df2f7094f8660c9496430e17be2d 196 SUPERFAMILY SSF47413 6 73 3.2E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Theos_2098 b699d5cc7a39e87597897a8c8cc4dd49 65 SUPERFAMILY SSF143100 1 56 5.49E-20 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like Theos_2098 b699d5cc7a39e87597897a8c8cc4dd49 65 Gene3D G3DSA:3.30.160.250 1 64 7.5E-21 T 14-10-2018 Theos_2098 b699d5cc7a39e87597897a8c8cc4dd49 65 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 57 6.9E-15 T 14-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system Theos_1638 7836f10effe452ceabd831f1fe219968 77 Pfam PF05534 HicB family 8 36 4.0E-6 T 14-10-2018 IPR008651 Uncharacterised protein family HicB Theos_1638 7836f10effe452ceabd831f1fe219968 77 SUPERFAMILY SSF47598 8 55 1.68E-8 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Theos_0962 e8c817c6b8da2850e1464f18c337f34b 147 Pfam PF12802 MarR family 20 77 3.6E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_0962 e8c817c6b8da2850e1464f18c337f34b 147 Gene3D G3DSA:1.10.287.160 88 147 5.7E-5 T 14-10-2018 Theos_0962 e8c817c6b8da2850e1464f18c337f34b 147 Gene3D G3DSA:1.10.10.10 1 86 3.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0962 e8c817c6b8da2850e1464f18c337f34b 147 SUPERFAMILY SSF46785 7 131 1.33E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0687 fc41ef412df73ea12ef054938cd4f7ed 129 SUPERFAMILY SSF47240 3 112 1.19E-9 T 14-10-2018 IPR009078 Ferritin-like superfamily Theos_0687 fc41ef412df73ea12ef054938cd4f7ed 129 Pfam PF02915 Rubrerythrin 5 63 6.2E-6 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Theos_0849 48704de878d1d4e2113a3213b2db0797 891 ProSitePatterns PS00018 EF-hand calcium-binding domain. 863 875 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site Theos_0849 48704de878d1d4e2113a3213b2db0797 891 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 779 827 1.2E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0849 48704de878d1d4e2113a3213b2db0797 891 Pfam PF01345 Domain of unknown function DUF11 200 330 1.9E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0849 48704de878d1d4e2113a3213b2db0797 891 Pfam PF01345 Domain of unknown function DUF11 777 860 3.0E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0849 48704de878d1d4e2113a3213b2db0797 891 Gene3D G3DSA:2.60.40.740 187 349 7.0E-5 T 14-10-2018 Theos_1413 78889dd3400410851a37722fde164524 283 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 124 154 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 Theos_1413 78889dd3400410851a37722fde164524 283 SUPERFAMILY SSF51569 2 263 4.81E-62 T 14-10-2018 Theos_1413 78889dd3400410851a37722fde164524 283 SMART SM01130 1 277 1.4E-56 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_1413 78889dd3400410851a37722fde164524 283 Gene3D G3DSA:3.20.20.70 1 283 1.3E-104 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1413 78889dd3400410851a37722fde164524 283 PIRSF PIRSF001365 1 265 1.2E-58 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_1413 78889dd3400410851a37722fde164524 283 Pfam PF00701 Dihydrodipicolinate synthetase family 2 260 2.2E-41 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_1413 78889dd3400410851a37722fde164524 283 PRINTS PR00146 Dihydrodipicolinate synthase signature 119 136 7.0E-8 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_1413 78889dd3400410851a37722fde164524 283 PRINTS PR00146 Dihydrodipicolinate synthase signature 96 112 7.0E-8 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_1413 78889dd3400410851a37722fde164524 283 PRINTS PR00146 Dihydrodipicolinate synthase signature 31 52 7.0E-8 T 14-10-2018 IPR002220 DapA-like GO:0016829 Theos_1995 7d71b18640d8ca3fe7130848a5c14a9f 359 PIRSF PIRSF037420 2 354 3.7E-90 T 14-10-2018 IPR017200 Coenzyme PQQ synthesis protein E Theos_1995 7d71b18640d8ca3fe7130848a5c14a9f 359 Gene3D G3DSA:3.20.20.70 9 298 2.2E-38 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1995 7d71b18640d8ca3fe7130848a5c14a9f 359 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 4 347 1.7E-138 T 14-10-2018 IPR027634 Radical SAM protein, BA_1875 family Theos_1995 7d71b18640d8ca3fe7130848a5c14a9f 359 Pfam PF04055 Radical SAM superfamily 15 153 3.2E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_1995 7d71b18640d8ca3fe7130848a5c14a9f 359 SUPERFAMILY SSF102114 4 324 4.84E-62 T 14-10-2018 Theos_1995 7d71b18640d8ca3fe7130848a5c14a9f 359 SMART SM00729 10 213 0.0012 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Theos_2282 dc95a719a020fc398d8bf2f414dc8980 563 SUPERFAMILY SSF53300 29 179 5.72E-13 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_2282 dc95a719a020fc398d8bf2f414dc8980 563 Gene3D G3DSA:3.40.50.410 26 197 4.4E-12 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_2282 dc95a719a020fc398d8bf2f414dc8980 563 Pfam PF13519 von Willebrand factor type A domain 30 137 3.6E-6 T 14-10-2018 IPR002035 von Willebrand factor, type A Theos_0190 8630962eeefabd504e2e3cc8c0049541 344 Gene3D G3DSA:3.40.190.10 118 327 1.3E-102 T 14-10-2018 Theos_0190 8630962eeefabd504e2e3cc8c0049541 344 Pfam PF13343 Bacterial extracellular solute-binding protein 67 289 6.3E-29 T 14-10-2018 Theos_0190 8630962eeefabd504e2e3cc8c0049541 344 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 17 326 6.7E-94 T 14-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 Theos_0190 8630962eeefabd504e2e3cc8c0049541 344 Gene3D G3DSA:3.40.190.10 20 302 1.3E-102 T 14-10-2018 Theos_0190 8630962eeefabd504e2e3cc8c0049541 344 SUPERFAMILY SSF53850 17 332 4.25E-60 T 14-10-2018 Theos_2524 7d19f7fc1b3761d50c15a5696d5ddf50 78 SUPERFAMILY SSF46689 6 70 1.63E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_2524 7d19f7fc1b3761d50c15a5696d5ddf50 78 Pfam PF04255 Protein of unknown function (DUF433) 10 65 3.9E-24 T 14-10-2018 IPR007367 Protein of unknown function DUF433 Theos_2524 7d19f7fc1b3761d50c15a5696d5ddf50 78 Gene3D G3DSA:1.10.10.10 9 76 3.9E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0929 c5384ce3e06a67d126169511544e6064 323 SUPERFAMILY SSF46785 20 60 2.15E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0929 c5384ce3e06a67d126169511544e6064 323 Gene3D G3DSA:1.10.10.10 1 63 3.5E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0929 c5384ce3e06a67d126169511544e6064 323 Pfam PF08279 HTH domain 12 55 2.2E-6 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 Theos_0929 c5384ce3e06a67d126169511544e6064 323 Pfam PF13280 WYL domain 128 310 3.1E-37 T 14-10-2018 IPR026881 WYL domain Theos_2127 af52fdcda4955d2d1396f9eea6bc6957 100 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 9 92 5.6E-29 T 14-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 Theos_0989 4d0a1126091d449a734f3e5b2c107b70 192 SUPERFAMILY SSF46689 2 69 1.13E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_0989 4d0a1126091d449a734f3e5b2c107b70 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_0989 4d0a1126091d449a734f3e5b2c107b70 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 2.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_0989 4d0a1126091d449a734f3e5b2c107b70 192 Gene3D G3DSA:1.10.357.10 50 182 1.0E-41 T 14-10-2018 Theos_0989 4d0a1126091d449a734f3e5b2c107b70 192 Gene3D G3DSA:1.10.10.60 2 49 1.4E-14 T 14-10-2018 Theos_0989 4d0a1126091d449a734f3e5b2c107b70 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 9.2E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_0989 4d0a1126091d449a734f3e5b2c107b70 192 SUPERFAMILY SSF48498 71 183 9.79E-27 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Theos_0782 627fadb0c7ae782ef57ce56e2dabb7df 215 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 4 215 1.9E-52 T 14-10-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 Theos_0782 627fadb0c7ae782ef57ce56e2dabb7df 215 Pfam PF01048 Phosphorylase superfamily 26 205 2.1E-19 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Theos_0782 627fadb0c7ae782ef57ce56e2dabb7df 215 Hamap MF_00991 Futalosine hydrolase [mqnB]. 22 215 21.212 T 14-10-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 Theos_0782 627fadb0c7ae782ef57ce56e2dabb7df 215 Gene3D G3DSA:3.40.50.1580 24 215 3.8E-28 T 14-10-2018 Theos_0782 627fadb0c7ae782ef57ce56e2dabb7df 215 SUPERFAMILY SSF53167 28 198 2.36E-24 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Theos_1402 400e2a9206384d95ad9fbef2026f13ed 133 Pfam PF00011 Hsp20/alpha crystallin family 42 127 5.8E-12 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Theos_1402 400e2a9206384d95ad9fbef2026f13ed 133 Gene3D G3DSA:2.60.40.790 6 130 1.7E-24 T 14-10-2018 IPR008978 HSP20-like chaperone Theos_1402 400e2a9206384d95ad9fbef2026f13ed 133 SUPERFAMILY SSF49764 25 127 9.77E-23 T 14-10-2018 IPR008978 HSP20-like chaperone Theos_1445 d6b0a81a6e6f082a22de587251d62620 188 SUPERFAMILY SSF52317 2 185 8.35E-47 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1445 d6b0a81a6e6f082a22de587251d62620 188 Pfam PF01174 SNO glutamine amidotransferase family 4 184 1.3E-59 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_1445 d6b0a81a6e6f082a22de587251d62620 188 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 2 185 37.229 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_1445 d6b0a81a6e6f082a22de587251d62620 188 ProSitePatterns PS01236 PdxT/SNO family family signature. 39 49 - T 14-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_1445 d6b0a81a6e6f082a22de587251d62620 188 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 184 3.7E-66 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_1445 d6b0a81a6e6f082a22de587251d62620 188 PIRSF PIRSF005639 1 187 3.5E-66 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Theos_1445 d6b0a81a6e6f082a22de587251d62620 188 Gene3D G3DSA:3.40.50.880 1 187 1.4E-64 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_1015 e7d3058abf85e7448e0f4c39058a6836 125 Gene3D G3DSA:3.40.30.10 21 95 3.7E-12 T 14-10-2018 Theos_1015 e7d3058abf85e7448e0f4c39058a6836 125 Pfam PF14595 Thioredoxin 23 91 1.7E-17 T 14-10-2018 Theos_1015 e7d3058abf85e7448e0f4c39058a6836 125 SUPERFAMILY SSF52833 24 90 1.39E-8 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_1744 a84339fbb711b5f6cc42e8745e23341d 230 SUPERFAMILY SSF142823 4 218 1.44E-54 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Theos_1744 a84339fbb711b5f6cc42e8745e23341d 230 Gene3D G3DSA:3.90.1560.10 5 229 2.6E-65 T 14-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Theos_1744 a84339fbb711b5f6cc42e8745e23341d 230 Pfam PF04029 2-phosphosulpholactate phosphatase 13 218 2.2E-59 T 14-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Theos_1307 8f6364048c744391059140b6d1208118 691 Gene3D G3DSA:3.40.50.300 367 558 8.0E-25 T 14-10-2018 Theos_1307 8f6364048c744391059140b6d1208118 691 Pfam PF01935 Domain of unknown function DUF87 183 418 1.7E-23 T 14-10-2018 IPR002789 Helicase HerA, central domain Theos_1307 8f6364048c744391059140b6d1208118 691 SUPERFAMILY SSF52540 180 550 3.72E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1273 8be701c6783e313987c47ecaeee8a644 440 SUPERFAMILY SSF53300 71 191 3.21E-5 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_1945 1dc98c51140aa4ee3bc5abadc69e7d47 173 SUPERFAMILY SSF160369 7 171 2.62E-45 T 14-10-2018 Theos_1945 1dc98c51140aa4ee3bc5abadc69e7d47 173 Pfam PF00466 Ribosomal protein L10 4 98 9.0E-21 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 Theos_1945 1dc98c51140aa4ee3bc5abadc69e7d47 173 Gene3D G3DSA:3.30.70.1730 2 133 8.0E-39 T 14-10-2018 Theos_1945 1dc98c51140aa4ee3bc5abadc69e7d47 173 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 15 143 8.0E-7 T 14-10-2018 Theos_1945 1dc98c51140aa4ee3bc5abadc69e7d47 173 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 2 160 21.767 T 14-10-2018 IPR022973 Ribosomal protein L10 Theos_0976 d68d2dfb3feddb641831f4e535f91707 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 308 4.5E-25 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_2110 13ffeb57e3e4e0dbdb9016ddc908d15b 222 Hamap MF_02088 Probable queuosine precursor transporter. 1 209 17.067 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 Theos_2110 13ffeb57e3e4e0dbdb9016ddc908d15b 222 Pfam PF02592 Putative vitamin uptake transporter 35 196 8.5E-50 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 Theos_2110 13ffeb57e3e4e0dbdb9016ddc908d15b 222 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 8 203 7.5E-41 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 Theos_1957 ce58cebcf817150f459acc1d2ed0c0d5 305 SUPERFAMILY SSF51730 1 291 5.49E-100 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like Theos_1957 ce58cebcf817150f459acc1d2ed0c0d5 305 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 15 287 8.0E-97 T 14-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 Theos_1957 ce58cebcf817150f459acc1d2ed0c0d5 305 Pfam PF02219 Methylenetetrahydrofolate reductase 3 288 7.8E-93 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Theos_1957 ce58cebcf817150f459acc1d2ed0c0d5 305 Gene3D G3DSA:3.20.20.220 1 292 6.0E-120 T 14-10-2018 Theos_1235 68226cdd444ae1ca1be1971bdc9a1b75 156 SUPERFAMILY SSF54523 4 88 2.67E-9 T 14-10-2018 Theos_1235 68226cdd444ae1ca1be1971bdc9a1b75 156 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 2 22 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1235 68226cdd444ae1ca1be1971bdc9a1b75 156 Pfam PF12019 Type II transport protein GspH 37 151 5.1E-9 T 14-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 Theos_1235 68226cdd444ae1ca1be1971bdc9a1b75 156 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 22 1.1E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1235 68226cdd444ae1ca1be1971bdc9a1b75 156 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 24 3.5E-6 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_2143 74e6ab83337cca937f0171f70ce296c2 118 Gene3D G3DSA:3.30.1130.10 1 118 1.4E-34 T 14-10-2018 Theos_2143 74e6ab83337cca937f0171f70ce296c2 118 SUPERFAMILY SSF55620 4 116 4.45E-31 T 14-10-2018 Theos_2143 74e6ab83337cca937f0171f70ce296c2 118 SMART SM00905 4 115 1.3E-39 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Theos_2143 74e6ab83337cca937f0171f70ce296c2 118 Pfam PF02152 Dihydroneopterin aldolase 4 112 4.9E-29 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Theos_2143 74e6ab83337cca937f0171f70ce296c2 118 TIGRFAM TIGR00526 folB_dom: FolB domain 4 111 4.0E-20 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Theos_2143 74e6ab83337cca937f0171f70ce296c2 118 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 112 1.3E-31 T 14-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Theos_0823 a04a1bc741022cb9e76d0dd22b9d6a39 220 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 1 202 23.208 T 14-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0823 a04a1bc741022cb9e76d0dd22b9d6a39 220 Pfam PF01813 ATP synthase subunit D 10 196 1.2E-51 T 14-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_0823 a04a1bc741022cb9e76d0dd22b9d6a39 220 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 1 201 3.2E-43 T 14-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Theos_1187 29742ec6fd8bab558c4db0f75b8a18d1 261 Gene3D G3DSA:1.10.3720.10 48 258 4.4E-52 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1187 29742ec6fd8bab558c4db0f75b8a18d1 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 67 257 8.3E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1187 29742ec6fd8bab558c4db0f75b8a18d1 261 SUPERFAMILY SSF161098 50 242 1.02E-44 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1187 29742ec6fd8bab558c4db0f75b8a18d1 261 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 48 151 2.1E-22 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 Theos_0359 44941f02e2cb604d2e7d20d40ecd10a0 175 Pfam PF00156 Phosphoribosyl transferase domain 36 170 9.6E-7 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Theos_0359 44941f02e2cb604d2e7d20d40ecd10a0 175 Gene3D G3DSA:3.40.50.2020 1 175 1.3E-43 T 14-10-2018 Theos_0359 44941f02e2cb604d2e7d20d40ecd10a0 175 SUPERFAMILY SSF53271 7 162 1.71E-21 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_2059 7fd5209f84b050b4d325e646dd342e22 876 Pfam PF12838 4Fe-4S dicluster domain 725 822 5.6E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_2059 7fd5209f84b050b4d325e646dd342e22 876 Pfam PF12838 4Fe-4S dicluster domain 642 710 1.2E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Theos_2059 7fd5209f84b050b4d325e646dd342e22 876 Gene3D G3DSA:3.30.70.20 632 717 1.4E-16 T 14-10-2018 Theos_2059 7fd5209f84b050b4d325e646dd342e22 876 Gene3D G3DSA:3.30.70.20 718 869 3.9E-25 T 14-10-2018 Theos_2059 7fd5209f84b050b4d325e646dd342e22 876 SUPERFAMILY SSF54862 634 865 3.14E-48 T 14-10-2018 Theos_0595 c6ec0917a89953709f9b64bf79276413 556 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 465 485 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site Theos_0595 c6ec0917a89953709f9b64bf79276413 556 Gene3D G3DSA:1.20.1730.10 336 544 2.7E-25 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily Theos_0595 c6ec0917a89953709f9b64bf79276413 556 Gene3D G3DSA:1.20.1730.10 8 323 6.2E-38 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily Theos_0595 c6ec0917a89953709f9b64bf79276413 556 Pfam PF00474 Sodium:solute symporter family 368 483 1.4E-19 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Theos_0595 c6ec0917a89953709f9b64bf79276413 556 Pfam PF00474 Sodium:solute symporter family 33 297 3.1E-35 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Theos_0595 c6ec0917a89953709f9b64bf79276413 556 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 7 547 4.1E-239 T 14-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily Theos_2396 7c7acb40125654fe4dcd346ccd6346a3 312 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2396 7c7acb40125654fe4dcd346ccd6346a3 312 Pfam PF00005 ABC transporter 18 153 4.6E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2396 7c7acb40125654fe4dcd346ccd6346a3 312 SUPERFAMILY SSF52540 1 230 6.66E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2396 7c7acb40125654fe4dcd346ccd6346a3 312 SMART SM00382 25 205 9.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2396 7c7acb40125654fe4dcd346ccd6346a3 312 Gene3D G3DSA:3.40.50.300 1 234 7.6E-68 T 14-10-2018 Theos_0487 c62d7b86313fb7ce5d8f0ed42b372ad1 103 Pfam PF03091 CutA1 divalent ion tolerance protein 4 100 1.2E-38 T 14-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 Theos_0487 c62d7b86313fb7ce5d8f0ed42b372ad1 103 Gene3D G3DSA:3.30.70.120 1 103 3.6E-43 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Theos_0487 c62d7b86313fb7ce5d8f0ed42b372ad1 103 SUPERFAMILY SSF54913 4 102 2.45E-38 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Theos_0229 c5a6b532dfa70911675e7327cc070da0 316 SUPERFAMILY SSF52540 7 294 4.99E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0229 c5a6b532dfa70911675e7327cc070da0 316 Pfam PF03308 ArgK protein 24 278 1.6E-96 T 14-10-2018 Theos_0229 c5a6b532dfa70911675e7327cc070da0 316 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 19 306 6.2E-96 T 14-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Theos_0229 c5a6b532dfa70911675e7327cc070da0 316 Gene3D G3DSA:3.40.50.300 45 256 9.0E-84 T 14-10-2018 Theos_0458 edb63c71c3281ed004252c65f5a7b0be 469 Pfam PF04932 O-Antigen ligase 149 297 2.9E-7 T 14-10-2018 IPR007016 O-antigen ligase-related Theos_1162 37f691c9235a6e203347b562a4c75000 302 SMART SM00849 90 276 5.9E-16 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_1162 37f691c9235a6e203347b562a4c75000 302 Gene3D G3DSA:3.60.15.10 32 301 2.9E-76 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1162 37f691c9235a6e203347b562a4c75000 302 Pfam PF00753 Metallo-beta-lactamase superfamily 92 233 3.3E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_1162 37f691c9235a6e203347b562a4c75000 302 SUPERFAMILY SSF56281 32 299 4.06E-42 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_2472 c626a418b3335d087a7b7736631a7258 64 Pfam PF01361 Tautomerase enzyme 4 60 4.1E-15 T 14-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 Theos_2472 c626a418b3335d087a7b7736631a7258 64 SUPERFAMILY SSF55331 2 62 1.57E-15 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily Theos_2472 c626a418b3335d087a7b7736631a7258 64 Gene3D G3DSA:3.30.429.10 2 64 3.1E-20 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily Theos_1927 ffe0b905399509b5767aeedde2b11b1c 216 Pfam PF08378 Nuclease-related domain 71 167 4.7E-17 T 14-10-2018 IPR011528 Nuclease-related domain, NERD Theos_1987 3a89098762ef71724aeb2d074bc7a10e 232 Gene3D G3DSA:3.40.50.150 16 232 4.9E-66 T 14-10-2018 Theos_1987 3a89098762ef71724aeb2d074bc7a10e 232 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 21 36 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 Theos_1987 3a89098762ef71724aeb2d074bc7a10e 232 Pfam PF01209 ubiE/COQ5 methyltransferase family 6 231 6.0E-64 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 Theos_1987 3a89098762ef71724aeb2d074bc7a10e 232 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 231 36.894 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 Theos_1987 3a89098762ef71724aeb2d074bc7a10e 232 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 10 231 2.7E-78 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 Theos_1987 3a89098762ef71724aeb2d074bc7a10e 232 SUPERFAMILY SSF53335 6 217 2.41E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 45 57 1.0E-26 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 29 39 1.0E-26 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 16 28 1.0E-26 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 356 368 1.0E-26 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 329 335 1.0E-26 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 97 109 1.0E-26 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 SUPERFAMILY SSF51905 11 260 1.2E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 Gene3D G3DSA:3.30.9.10 101 336 1.6E-109 T 14-10-2018 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 490 1.1E-22 T 14-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 Gene3D G3DSA:1.10.8.870 399 503 1.7E-27 T 14-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 Gene3D G3DSA:3.50.50.60 17 375 1.6E-109 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 SUPERFAMILY SSF54373 247 335 4.9E-7 T 14-10-2018 Theos_0838 16dbcf729a34361d3dafb389c047dfad 506 Pfam PF01266 FAD dependent oxidoreductase 17 365 6.4E-48 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Theos_0763 161a5b28cfc11223783b7c1e45f7394e 152 Gene3D G3DSA:3.40.50.2020 1 150 4.5E-34 T 14-10-2018 Theos_0763 161a5b28cfc11223783b7c1e45f7394e 152 Pfam PF00156 Phosphoribosyl transferase domain 11 145 1.1E-11 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Theos_0763 161a5b28cfc11223783b7c1e45f7394e 152 SUPERFAMILY SSF53271 3 148 5.68E-29 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_1810 74d67dbff05b0fca973cb7ed9c245cee 135 Pfam PF03061 Thioesterase superfamily 47 118 1.4E-15 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Theos_1810 74d67dbff05b0fca973cb7ed9c245cee 135 Gene3D G3DSA:3.10.129.10 1 132 9.4E-37 T 14-10-2018 Theos_1810 74d67dbff05b0fca973cb7ed9c245cee 135 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 17 131 4.6E-19 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 Theos_1810 74d67dbff05b0fca973cb7ed9c245cee 135 SUPERFAMILY SSF54637 3 130 2.56E-31 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_0993 d646323f56252d410a6d77f60719041e 151 Pfam PF01883 Iron-sulfur cluster assembly protein 6 76 7.0E-16 T 14-10-2018 IPR002744 MIP18 family-like Theos_0993 d646323f56252d410a6d77f60719041e 151 SUPERFAMILY SSF117916 6 94 8.94E-18 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Theos_0993 d646323f56252d410a6d77f60719041e 151 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 12 151 2.0E-46 T 14-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit Theos_0993 d646323f56252d410a6d77f60719041e 151 Gene3D G3DSA:3.30.300.130 1 95 5.7E-22 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Theos_1153 1d88385a8751653e24a91729528d000c 132 Pfam PF01219 Prokaryotic diacylglycerol kinase 23 121 2.3E-29 T 14-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 Theos_1153 1d88385a8751653e24a91729528d000c 132 Gene3D G3DSA:1.10.3830.10 11 125 2.1E-34 T 14-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 Theos_1111 c11b77b726e7056a606066adf73606eb 245 Gene3D G3DSA:3.40.140.10 97 238 2.3E-36 T 14-10-2018 Theos_1111 c11b77b726e7056a606066adf73606eb 245 Pfam PF02634 FdhD/NarQ family 18 232 2.9E-44 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Theos_1111 c11b77b726e7056a606066adf73606eb 245 SUPERFAMILY SSF53927 2 232 1.65E-47 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Theos_0074 111fcbd8542b1178ea056e0999716d83 267 Pfam PF14332 Domain of unknown function (DUF4388) 9 93 3.1E-11 T 14-10-2018 IPR025497 Domain of unknown function DUF4388 Theos_0807 c486fc33b9cccb4b9862af6db300cb1e 351 Gene3D G3DSA:3.30.160.250 2 77 3.3E-11 T 14-10-2018 Theos_0807 c486fc33b9cccb4b9862af6db300cb1e 351 SUPERFAMILY SSF52980 111 337 9.12E-29 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_0807 c486fc33b9cccb4b9862af6db300cb1e 351 Gene3D G3DSA:3.40.1350.10 216 349 8.7E-7 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 Theos_0807 c486fc33b9cccb4b9862af6db300cb1e 351 SUPERFAMILY SSF143100 25 71 1.18E-5 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like Theos_1197 f2181acd4aaf614390195a560fef441d 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 86 101 8.2E-21 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Theos_1197 f2181acd4aaf614390195a560fef441d 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 53 69 8.2E-21 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Theos_1197 f2181acd4aaf614390195a560fef441d 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 8.2E-21 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Theos_1197 f2181acd4aaf614390195a560fef441d 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 10 27 8.2E-21 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Theos_1197 f2181acd4aaf614390195a560fef441d 157 Gene3D G3DSA:3.40.50.2300 4 155 5.8E-63 T 14-10-2018 Theos_1197 f2181acd4aaf614390195a560fef441d 157 SUPERFAMILY SSF52788 6 151 2.49E-48 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Theos_1197 f2181acd4aaf614390195a560fef441d 157 SMART SM00226 8 152 4.2E-49 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Theos_1197 f2181acd4aaf614390195a560fef441d 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 148 9.2E-39 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Theos_0325 1956b25dd0acc820fa35b1c870b5bae1 229 ProSitePatterns PS01057 SAICAR synthetase signature 1. 81 95 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0325 1956b25dd0acc820fa35b1c870b5bae1 229 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 227 4.4E-66 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 Theos_0325 1956b25dd0acc820fa35b1c870b5bae1 229 SUPERFAMILY SSF56104 1 229 1.8E-80 T 14-10-2018 Theos_0325 1956b25dd0acc820fa35b1c870b5bae1 229 ProSitePatterns PS01058 SAICAR synthetase signature 2. 168 176 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0325 1956b25dd0acc820fa35b1c870b5bae1 229 Gene3D G3DSA:3.30.200.20 3 226 9.3E-88 T 14-10-2018 Theos_0325 1956b25dd0acc820fa35b1c870b5bae1 229 Gene3D G3DSA:3.30.470.20 80 215 9.3E-88 T 14-10-2018 Theos_0325 1956b25dd0acc820fa35b1c870b5bae1 229 Pfam PF01259 SAICAR synthetase 3 226 1.4E-60 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_0325 1956b25dd0acc820fa35b1c870b5bae1 229 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 229 31.131 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Theos_1652 67436f6985e06fa21cd97aa9345cd31e 215 Pfam PF03358 NADPH-dependent FMN reductase 4 161 1.1E-26 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Theos_1652 67436f6985e06fa21cd97aa9345cd31e 215 SUPERFAMILY SSF52218 1 192 1.49E-39 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Theos_1652 67436f6985e06fa21cd97aa9345cd31e 215 Gene3D G3DSA:3.40.50.360 1 196 1.3E-33 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Theos_2209 78071770ce9c056a3a9156bad62a51e8 323 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 116 1.4E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Theos_2209 78071770ce9c056a3a9156bad62a51e8 323 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 149 267 6.3E-16 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Theos_2209 78071770ce9c056a3a9156bad62a51e8 323 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 245 266 - T 14-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 Theos_2209 78071770ce9c056a3a9156bad62a51e8 323 SUPERFAMILY SSF54593 4 268 2.61E-41 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_2209 78071770ce9c056a3a9156bad62a51e8 323 Gene3D G3DSA:3.10.180.10 1 134 5.3E-36 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_2209 78071770ce9c056a3a9156bad62a51e8 323 TIGRFAM TIGR03211 catechol_2_3: catechol 2,3 dioxygenase 5 313 1.9E-103 T 14-10-2018 IPR017624 Catechol 2,3 dioxygenase GO:0008198|GO:0018577|GO:0019439|GO:0055114 KEGG: 00361+1.13.11.2|KEGG: 00362+1.13.11.2|KEGG: 00622+1.13.11.2|KEGG: 00643+1.13.11.2|MetaCyc: PWY-5419|MetaCyc: PWY-5641 Theos_2209 78071770ce9c056a3a9156bad62a51e8 323 Gene3D G3DSA:3.10.180.10 148 321 1.3E-44 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_0887 a05fb9cd8cdbe152c638d4a3264dcc01 187 Pfam PF01205 Uncharacterized protein family UPF0029 15 114 8.7E-28 T 14-10-2018 IPR001498 Impact, N-terminal Theos_0887 a05fb9cd8cdbe152c638d4a3264dcc01 187 Pfam PF09186 Domain of unknown function (DUF1949) 149 183 1.6E-6 T 14-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal Theos_0887 a05fb9cd8cdbe152c638d4a3264dcc01 187 SUPERFAMILY SSF54980 123 184 1.15E-10 T 14-10-2018 IPR035647 EF-G domain III/V-like Theos_0887 a05fb9cd8cdbe152c638d4a3264dcc01 187 Gene3D G3DSA:3.30.70.240 125 186 4.9E-17 T 14-10-2018 Theos_0887 a05fb9cd8cdbe152c638d4a3264dcc01 187 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 69 98 - T 14-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site Theos_0887 a05fb9cd8cdbe152c638d4a3264dcc01 187 Gene3D G3DSA:3.30.230.30 1 123 6.3E-48 T 14-10-2018 IPR036956 Impact, N-terminal domain superfamily Theos_0887 a05fb9cd8cdbe152c638d4a3264dcc01 187 SUPERFAMILY SSF54211 3 120 1.67E-38 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Theos_2155 dccc290733a97b394923f560d1c172b5 179 Pfam PF01936 NYN domain 3 160 2.3E-31 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type Theos_2155 dccc290733a97b394923f560d1c172b5 179 Gene3D G3DSA:3.40.50.1010 1 163 8.1E-41 T 14-10-2018 Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 258 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 22 393 5.3E-135 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 SUPERFAMILY SSF53383 23 393 1.48E-128 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 Pfam PF00202 Aminotransferase class-III 28 392 6.3E-114 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 Gene3D G3DSA:3.90.1150.10 29 387 2.0E-158 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 Gene3D G3DSA:3.40.640.10 62 303 2.0E-158 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 PIRSF PIRSF000521 13 147 1.4E-8 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 PIRSF PIRSF000521 167 394 2.4E-35 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 PIRSF PIRSF000521 130 162 16.0 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_2048 12ec94af40b77cc7fdd415f76963af9f 394 Hamap MF_02084 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase [lysJ]. 20 394 49.135 T 14-10-2018 IPR037537 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase GO:0008483 Theos_0729 9dc7994b0f5dff760abf3f5c03d78201 347 Gene3D G3DSA:3.40.640.10 45 254 2.4E-89 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0729 9dc7994b0f5dff760abf3f5c03d78201 347 Pfam PF00155 Aminotransferase class I and II 23 338 2.4E-47 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Theos_0729 9dc7994b0f5dff760abf3f5c03d78201 347 SUPERFAMILY SSF53383 11 340 6.05E-70 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0729 9dc7994b0f5dff760abf3f5c03d78201 347 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 3 345 47.433 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Theos_0729 9dc7994b0f5dff760abf3f5c03d78201 347 Gene3D G3DSA:3.90.1150.10 8 340 2.4E-89 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0729 9dc7994b0f5dff760abf3f5c03d78201 347 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 204 213 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 Theos_1042 3506c7203f21274538abe492224dcf7e 273 SUPERFAMILY SSF46626 122 223 8.34E-13 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1042 3506c7203f21274538abe492224dcf7e 273 SUPERFAMILY SSF46626 31 117 2.91E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1042 3506c7203f21274538abe492224dcf7e 273 Gene3D G3DSA:1.10.760.10 26 130 3.2E-28 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1042 3506c7203f21274538abe492224dcf7e 273 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 30 112 1.1E-12 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1042 3506c7203f21274538abe492224dcf7e 273 Gene3D G3DSA:1.10.760.10 139 231 3.5E-6 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1042 3506c7203f21274538abe492224dcf7e 273 Pfam PF00034 Cytochrome c 141 222 1.2E-4 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1824 62570a1d574cc53d34b821be55632fd4 247 Pfam PF08241 Methyltransferase domain 110 193 4.7E-18 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Theos_1824 62570a1d574cc53d34b821be55632fd4 247 Pfam PF07615 YKOF-related Family 3 64 3.2E-6 T 14-10-2018 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative Theos_1824 62570a1d574cc53d34b821be55632fd4 247 Gene3D G3DSA:3.40.50.150 86 244 1.5E-28 T 14-10-2018 Theos_1824 62570a1d574cc53d34b821be55632fd4 247 Gene3D G3DSA:3.30.70.930 1 76 4.9E-10 T 14-10-2018 IPR029756 MTH1187/YkoF-like Theos_1824 62570a1d574cc53d34b821be55632fd4 247 SUPERFAMILY SSF89957 1 113 1.31E-20 T 14-10-2018 IPR029756 MTH1187/YkoF-like Theos_1824 62570a1d574cc53d34b821be55632fd4 247 SUPERFAMILY SSF53335 100 227 2.3E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Theos_0358 27bfe34e76152b3258c3b46576260ce6 203 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 57 187 2.3E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0358 27bfe34e76152b3258c3b46576260ce6 203 Pfam PF13419 Haloacid dehalogenase-like hydrolase 78 190 1.0E-13 T 14-10-2018 Theos_0358 27bfe34e76152b3258c3b46576260ce6 203 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 2.4E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0358 27bfe34e76152b3258c3b46576260ce6 203 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 107 120 2.4E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0358 27bfe34e76152b3258c3b46576260ce6 203 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 2.4E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0358 27bfe34e76152b3258c3b46576260ce6 203 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 2.4E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0358 27bfe34e76152b3258c3b46576260ce6 203 SUPERFAMILY SSF56784 2 194 4.93E-30 T 14-10-2018 IPR036412 HAD-like superfamily Theos_0358 27bfe34e76152b3258c3b46576260ce6 203 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 95 189 3.1E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Theos_0358 27bfe34e76152b3258c3b46576260ce6 203 Gene3D G3DSA:3.40.50.1000 1 200 5.3E-31 T 14-10-2018 IPR023214 HAD superfamily Theos_2287 317e49159ed1838d54f209ed6e9635c4 313 Gene3D G3DSA:1.10.3720.10 76 311 5.3E-60 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2287 317e49159ed1838d54f209ed6e9635c4 313 SUPERFAMILY SSF161098 64 300 6.28E-51 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2287 317e49159ed1838d54f209ed6e9635c4 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 304 6.8E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0081 b5f9d7f0a7a5526a5b81bc9960bbd993 371 Pfam PF01546 Peptidase family M20/M25/M40 77 369 1.6E-25 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 Theos_0081 b5f9d7f0a7a5526a5b81bc9960bbd993 371 Pfam PF07687 Peptidase dimerisation domain 175 268 5.4E-16 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain Theos_0081 b5f9d7f0a7a5526a5b81bc9960bbd993 371 PIRSF PIRSF037238 1 371 1.0E-132 T 14-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase Theos_0081 b5f9d7f0a7a5526a5b81bc9960bbd993 371 SUPERFAMILY SSF53187 4 371 5.43E-49 T 14-10-2018 Theos_0081 b5f9d7f0a7a5526a5b81bc9960bbd993 371 SUPERFAMILY SSF55031 178 279 4.45E-17 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Theos_0081 b5f9d7f0a7a5526a5b81bc9960bbd993 371 Gene3D G3DSA:3.30.70.360 178 285 2.1E-111 T 14-10-2018 Theos_0081 b5f9d7f0a7a5526a5b81bc9960bbd993 371 Gene3D G3DSA:3.40.630.10 17 360 2.1E-111 T 14-10-2018 Theos_2191 a34a8f070d625552fcaf485bf6c3aacf 186 SUPERFAMILY SSF100950 5 185 3.35E-17 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Theos_2191 a34a8f070d625552fcaf485bf6c3aacf 186 Gene3D G3DSA:3.40.50.10420 32 186 5.9E-9 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Theos_2191 a34a8f070d625552fcaf485bf6c3aacf 186 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 5 148 7.1E-13 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Theos_1419 b4c1758be0112e131b28b4f2c5872c39 320 Gene3D G3DSA:1.20.1600.10 13 216 6.7E-20 T 14-10-2018 Theos_1419 b4c1758be0112e131b28b4f2c5872c39 320 SUPERFAMILY SSF56954 43 318 2.22E-33 T 14-10-2018 Theos_1419 b4c1758be0112e131b28b4f2c5872c39 320 Gene3D G3DSA:1.20.1600.10 217 319 9.6E-14 T 14-10-2018 Theos_1419 b4c1758be0112e131b28b4f2c5872c39 320 Pfam PF02321 Outer membrane efflux protein 217 318 1.0E-10 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Theos_1419 b4c1758be0112e131b28b4f2c5872c39 320 Pfam PF02321 Outer membrane efflux protein 61 162 8.0E-14 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Theos_2056 900f114d57e40234736f242a7ce78e96 170 Gene3D G3DSA:1.10.760.10 71 155 1.0E-11 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_2056 900f114d57e40234736f242a7ce78e96 170 SUPERFAMILY SSF46626 5 153 6.58E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_2056 900f114d57e40234736f242a7ce78e96 170 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 73 151 1.9E-11 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0961 12165c633079467b9433c49a918c2d03 133 SUPERFAMILY SSF81593 4 129 2.98E-40 T 14-10-2018 Theos_0961 12165c633079467b9433c49a918c2d03 133 Pfam PF05168 HEPN domain 6 128 1.8E-32 T 14-10-2018 IPR007842 HEPN domain Theos_0961 12165c633079467b9433c49a918c2d03 133 SMART SM00748 10 122 5.3E-37 T 14-10-2018 IPR007842 HEPN domain Theos_0961 12165c633079467b9433c49a918c2d03 133 Gene3D G3DSA:1.20.120.330 2 131 2.3E-37 T 14-10-2018 Theos_0088 715b660841949defae3b38fbe18e6553 462 Pfam PF00394 Multicopper oxidase 197 285 6.6E-13 T 14-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 Theos_0088 715b660841949defae3b38fbe18e6553 462 ProSitePatterns PS00080 Multicopper oxidases signature 2. 444 455 - T 14-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 Theos_0088 715b660841949defae3b38fbe18e6553 462 Pfam PF07732 Multicopper oxidase 53 158 1.0E-26 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 Theos_0088 715b660841949defae3b38fbe18e6553 462 Pfam PF07731 Multicopper oxidase 348 461 8.4E-25 T 14-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 Theos_0088 715b660841949defae3b38fbe18e6553 462 Gene3D G3DSA:2.60.40.420 335 462 5.8E-42 T 14-10-2018 IPR008972 Cupredoxin Theos_0088 715b660841949defae3b38fbe18e6553 462 SUPERFAMILY SSF49503 23 158 8.51E-32 T 14-10-2018 IPR008972 Cupredoxin Theos_0088 715b660841949defae3b38fbe18e6553 462 Gene3D G3DSA:2.60.40.420 158 334 2.3E-60 T 14-10-2018 IPR008972 Cupredoxin Theos_0088 715b660841949defae3b38fbe18e6553 462 Gene3D G3DSA:2.60.40.420 25 157 6.7E-44 T 14-10-2018 IPR008972 Cupredoxin Theos_0088 715b660841949defae3b38fbe18e6553 462 SUPERFAMILY SSF49503 318 461 1.7E-29 T 14-10-2018 IPR008972 Cupredoxin Theos_0088 715b660841949defae3b38fbe18e6553 462 SUPERFAMILY SSF49503 170 296 2.31E-24 T 14-10-2018 IPR008972 Cupredoxin Theos_2337 b9acefafb914dae97fbb18eb4a790bc6 145 SUPERFAMILY SSF54523 6 69 1.1E-5 T 14-10-2018 Theos_2337 b9acefafb914dae97fbb18eb4a790bc6 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 3.1E-7 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_2337 b9acefafb914dae97fbb18eb4a790bc6 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_2337 b9acefafb914dae97fbb18eb4a790bc6 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 1.1E-7 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1956 300d720314b2995c0428b03c0982ea43 430 SMART SM00849 13 200 6.9E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_1956 300d720314b2995c0428b03c0982ea43 430 SUPERFAMILY SSF56281 1 417 3.01E-127 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1956 300d720314b2995c0428b03c0982ea43 430 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 364 413 2.0E-12 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Theos_1956 300d720314b2995c0428b03c0982ea43 430 Pfam PF00753 Metallo-beta-lactamase superfamily 12 188 2.0E-16 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_1956 300d720314b2995c0428b03c0982ea43 430 SMART SM01027 227 350 3.3E-50 T 14-10-2018 IPR022712 Beta-Casp domain Theos_1956 300d720314b2995c0428b03c0982ea43 430 Gene3D G3DSA:3.40.50.10890 195 376 5.3E-152 T 14-10-2018 Theos_1956 300d720314b2995c0428b03c0982ea43 430 Pfam PF10996 Beta-Casp domain 227 350 6.4E-23 T 14-10-2018 IPR022712 Beta-Casp domain Theos_1956 300d720314b2995c0428b03c0982ea43 430 Gene3D G3DSA:3.60.15.10 6 404 5.3E-152 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_0264 444ae71d145df33efbff06d7fa6b7b65 305 Gene3D G3DSA:3.20.20.70 1 305 9.2E-135 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0264 444ae71d145df33efbff06d7fa6b7b65 305 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 2 305 5.4E-97 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Theos_0264 444ae71d145df33efbff06d7fa6b7b65 305 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 2 305 1.6E-112 T 14-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Theos_0264 444ae71d145df33efbff06d7fa6b7b65 305 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 304 3.2E-101 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Theos_0264 444ae71d145df33efbff06d7fa6b7b65 305 PIRSF PIRSF001359 1 305 4.2E-108 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Theos_0264 444ae71d145df33efbff06d7fa6b7b65 305 SUPERFAMILY SSF51569 1 305 2.78E-106 T 14-10-2018 Theos_1447 20cf1e97564dfff75cb9a7f97103deda 167 SUPERFAMILY SSF101874 26 166 1.57E-16 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Theos_1447 20cf1e97564dfff75cb9a7f97103deda 167 Gene3D G3DSA:2.40.128.110 25 167 6.7E-16 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Theos_1447 20cf1e97564dfff75cb9a7f97103deda 167 Pfam PF04264 YceI-like domain 38 164 1.7E-9 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Theos_1447 20cf1e97564dfff75cb9a7f97103deda 167 SMART SM00867 19 166 0.0028 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Theos_1417 bea70c7a96af81f092450c94d445f1a6 147 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 104 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site Theos_1417 bea70c7a96af81f092450c94d445f1a6 147 SUPERFAMILY SSF46785 11 143 2.64E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1417 bea70c7a96af81f092450c94d445f1a6 147 Pfam PF13463 Winged helix DNA-binding domain 44 104 5.5E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_1417 bea70c7a96af81f092450c94d445f1a6 147 Gene3D G3DSA:1.10.10.10 4 144 5.4E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_1417 bea70c7a96af81f092450c94d445f1a6 147 SMART SM00347 32 131 6.2E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_1417 bea70c7a96af81f092450c94d445f1a6 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 4.1E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_1417 bea70c7a96af81f092450c94d445f1a6 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 4.1E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_1417 bea70c7a96af81f092450c94d445f1a6 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 4.1E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_1417 bea70c7a96af81f092450c94d445f1a6 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 4.1E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Theos_1364 1d4b658ae8a842dd80996ccb5c34a43e 534 Gene3D G3DSA:3.40.50.12780 1 428 1.0E-174 T 14-10-2018 Theos_1364 1d4b658ae8a842dd80996ccb5c34a43e 534 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 517 6.5E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Theos_1364 1d4b658ae8a842dd80996ccb5c34a43e 534 SUPERFAMILY SSF56801 3 530 4.06E-148 T 14-10-2018 Theos_1364 1d4b658ae8a842dd80996ccb5c34a43e 534 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 14-10-2018 IPR020845 AMP-binding, conserved site Theos_1364 1d4b658ae8a842dd80996ccb5c34a43e 534 Pfam PF00501 AMP-binding enzyme 18 433 4.6E-95 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_1364 1d4b658ae8a842dd80996ccb5c34a43e 534 Gene3D G3DSA:3.30.300.310 429 534 8.4E-42 T 14-10-2018 Theos_2071 7a2b0f7b9bddd4250b3f6b1fe1298cc3 263 Pfam PF02673 Bacitracin resistance protein BacA 9 254 1.3E-64 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Theos_2071 7a2b0f7b9bddd4250b3f6b1fe1298cc3 263 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 259 15.792 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Theos_1981 84e708ae6d76de08af325c24cf9247ef 240 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 198 4.7E-18 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 Theos_1981 84e708ae6d76de08af325c24cf9247ef 240 Gene3D G3DSA:3.60.21.10 1 240 1.1E-49 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Theos_1981 84e708ae6d76de08af325c24cf9247ef 240 SUPERFAMILY SSF56300 2 239 6.81E-47 T 14-10-2018 Theos_1981 84e708ae6d76de08af325c24cf9247ef 240 PIRSF PIRSF000883 1 240 1.1E-41 T 14-10-2018 IPR011152 Phosphoesterase MJ0912 Theos_1405 c05c9658c11c3e736330356980ae60af 422 SUPERFAMILY SSF52096 18 187 9.95E-22 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_1405 c05c9658c11c3e736330356980ae60af 422 Pfam PF00574 Clp protease 20 111 9.9E-5 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Theos_1405 c05c9658c11c3e736330356980ae60af 422 Gene3D G3DSA:3.90.226.10 16 226 1.3E-45 T 14-10-2018 Theos_1405 c05c9658c11c3e736330356980ae60af 422 Pfam PF01957 NfeD-like C-terminal, partner-binding 278 419 6.9E-10 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain Theos_0559 d649c074b14eae8e86501da5de93a514 132 SUPERFAMILY SSF88723 1 121 2.19E-14 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_0559 d649c074b14eae8e86501da5de93a514 132 Gene3D G3DSA:3.40.50.1010 1 129 6.1E-13 T 14-10-2018 Theos_0559 d649c074b14eae8e86501da5de93a514 132 Pfam PF01850 PIN domain 4 125 2.4E-9 T 14-10-2018 IPR002716 PIN domain Theos_2307 7ce1f165a7ae445cb20421ad89d71fb8 199 Pfam PF11563 Protoglobin 30 167 2.7E-15 T 14-10-2018 Theos_2307 7ce1f165a7ae445cb20421ad89d71fb8 199 SUPERFAMILY SSF46458 31 152 1.3E-13 T 14-10-2018 IPR009050 Globin-like superfamily Theos_2307 7ce1f165a7ae445cb20421ad89d71fb8 199 Gene3D G3DSA:1.10.490.10 29 173 2.0E-20 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Theos_1179 cb3100c500b088656c32c53ac56f1388 136 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 66 112 1.2E-16 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 Theos_1179 cb3100c500b088656c32c53ac56f1388 136 SUPERFAMILY SSF46955 66 113 4.03E-6 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_1179 cb3100c500b088656c32c53ac56f1388 136 Pfam PF12728 Helix-turn-helix domain 66 113 9.3E-14 T 14-10-2018 Theos_1790 ed71ce381938bc8addaae4376a1e1b1d 68 Gene3D G3DSA:3.30.1660.10 1 68 1.6E-31 T 14-10-2018 IPR025543 Dodecin-like Theos_1790 ed71ce381938bc8addaae4376a1e1b1d 68 SUPERFAMILY SSF89807 4 67 1.83E-23 T 14-10-2018 IPR036694 Dodecin-like superfamily Theos_1790 ed71ce381938bc8addaae4376a1e1b1d 68 Pfam PF07311 Dodecin 4 67 2.7E-25 T 14-10-2018 IPR009923 Dodecin Theos_1605 d805a4b6dbc9a5f97a2eba913d1636c4 140 Pfam PF03918 Cytochrome C biogenesis protein 12 132 3.4E-33 T 14-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family Theos_1605 d805a4b6dbc9a5f97a2eba913d1636c4 140 Gene3D G3DSA:1.10.8.640 15 92 9.1E-26 T 14-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily Theos_0472 6af0cbe5123c1e11c5a025523a146275 330 Gene3D G3DSA:3.40.50.2000 75 321 4.2E-61 T 14-10-2018 Theos_0472 6af0cbe5123c1e11c5a025523a146275 330 SUPERFAMILY SSF53756 12 327 6.63E-73 T 14-10-2018 Theos_0472 6af0cbe5123c1e11c5a025523a146275 330 Gene3D G3DSA:3.40.50.2000 141 307 4.2E-61 T 14-10-2018 Theos_0472 6af0cbe5123c1e11c5a025523a146275 330 Pfam PF13439 Glycosyltransferase Family 4 15 142 4.7E-11 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Theos_0472 6af0cbe5123c1e11c5a025523a146275 330 Pfam PF00534 Glycosyl transferases group 1 157 303 1.9E-38 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Theos_1198 bded7ea15ac53b5a6f5144ae694528ba 515 Pfam PF07730 Histidine kinase 318 384 8.7E-20 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Theos_1198 bded7ea15ac53b5a6f5144ae694528ba 515 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 427 514 5.6E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_1198 bded7ea15ac53b5a6f5144ae694528ba 515 Gene3D G3DSA:3.30.450.40 171 314 7.8E-11 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_1198 bded7ea15ac53b5a6f5144ae694528ba 515 Gene3D G3DSA:3.30.565.10 389 515 1.7E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1198 bded7ea15ac53b5a6f5144ae694528ba 515 SUPERFAMILY SSF55781 179 307 9.6E-9 T 14-10-2018 Theos_1198 bded7ea15ac53b5a6f5144ae694528ba 515 SUPERFAMILY SSF55874 389 514 4.45E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_1198 bded7ea15ac53b5a6f5144ae694528ba 515 SMART SM00387 422 515 1.0E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0176 b13469da221ba8307c00fc75eb81a0a0 347 Gene3D G3DSA:1.20.1250.20 6 174 2.8E-12 T 14-10-2018 Theos_0176 b13469da221ba8307c00fc75eb81a0a0 347 Pfam PF07690 Major Facilitator Superfamily 11 309 7.3E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_0176 b13469da221ba8307c00fc75eb81a0a0 347 SUPERFAMILY SSF103473 5 337 8.5E-21 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_0176 b13469da221ba8307c00fc75eb81a0a0 347 Gene3D G3DSA:1.20.1250.20 181 344 9.5E-12 T 14-10-2018 Theos_1853 3864c68c7b552a840c8794de550826ec 319 SMART SM00829 10 317 9.2E-29 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Theos_1853 3864c68c7b552a840c8794de550826ec 319 Gene3D G3DSA:3.40.50.720 121 263 1.6E-118 T 14-10-2018 Theos_1853 3864c68c7b552a840c8794de550826ec 319 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 138 159 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 Theos_1853 3864c68c7b552a840c8794de550826ec 319 Gene3D G3DSA:3.90.180.10 9 316 1.6E-118 T 14-10-2018 Theos_1853 3864c68c7b552a840c8794de550826ec 319 Pfam PF00107 Zinc-binding dehydrogenase 149 248 2.9E-25 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Theos_1853 3864c68c7b552a840c8794de550826ec 319 SUPERFAMILY SSF50129 1 142 5.63E-42 T 14-10-2018 IPR011032 GroES-like superfamily Theos_1853 3864c68c7b552a840c8794de550826ec 319 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 86 1.5E-10 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Theos_1853 3864c68c7b552a840c8794de550826ec 319 SUPERFAMILY SSF51735 109 273 1.24E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_2000 88fb1ab08a168426478eab23f5da44c9 394 Gene3D G3DSA:3.40.190.10 130 387 5.0E-72 T 14-10-2018 Theos_2000 88fb1ab08a168426478eab23f5da44c9 394 Pfam PF13416 Bacterial extracellular solute-binding protein 36 336 1.8E-33 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_2000 88fb1ab08a168426478eab23f5da44c9 394 SUPERFAMILY SSF53850 19 387 1.83E-73 T 14-10-2018 Theos_2000 88fb1ab08a168426478eab23f5da44c9 394 Gene3D G3DSA:3.40.190.10 21 351 5.0E-72 T 14-10-2018 Theos_1507 07ab31deeb58bf10291b0edd6e5e8ecb 120 SMART SM00448 2 111 1.0E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_1507 07ab31deeb58bf10291b0edd6e5e8ecb 120 Gene3D G3DSA:3.40.50.2300 1 120 1.6E-32 T 14-10-2018 Theos_1507 07ab31deeb58bf10291b0edd6e5e8ecb 120 Pfam PF00072 Response regulator receiver domain 4 111 1.9E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Theos_1507 07ab31deeb58bf10291b0edd6e5e8ecb 120 SUPERFAMILY SSF52172 1 116 2.42E-34 T 14-10-2018 IPR011006 CheY-like superfamily Theos_2400 0b30907f75258f2019d3524ad87caadb 252 Pfam PF01614 Bacterial transcriptional regulator 126 248 3.0E-35 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal Theos_2400 0b30907f75258f2019d3524ad87caadb 252 Pfam PF09339 IclR helix-turn-helix domain 13 62 1.1E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Theos_2400 0b30907f75258f2019d3524ad87caadb 252 SMART SM00346 11 98 6.0E-18 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Theos_2400 0b30907f75258f2019d3524ad87caadb 252 Gene3D G3DSA:3.30.450.40 77 252 4.0E-64 T 14-10-2018 IPR029016 GAF-like domain superfamily Theos_2400 0b30907f75258f2019d3524ad87caadb 252 Gene3D G3DSA:1.10.10.10 3 76 4.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2400 0b30907f75258f2019d3524ad87caadb 252 SUPERFAMILY SSF55781 74 251 1.18E-54 T 14-10-2018 Theos_2400 0b30907f75258f2019d3524ad87caadb 252 SUPERFAMILY SSF46785 12 81 3.12E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1471 9f755f4b73546de9b95168c3b2aab792 218 Pfam PF02163 Peptidase family M50 141 173 2.0E-7 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Theos_0749 130b6a68c8fd0281cf0e9561801d998f 252 Gene3D G3DSA:1.20.1630.10 1 252 1.7E-112 T 14-10-2018 Theos_0749 130b6a68c8fd0281cf0e9561801d998f 252 Pfam PF14589 Polysulfide reductase 1 245 1.6E-48 T 14-10-2018 IPR032796 Polysulfide reductase Theos_1869 d18b2928e75a5cdb85cecd7f6d6c72cd 189 SUPERFAMILY SSF55729 6 171 7.97E-34 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_1869 d18b2928e75a5cdb85cecd7f6d6c72cd 189 Gene3D G3DSA:3.40.630.30 1 188 8.6E-54 T 14-10-2018 Theos_1869 d18b2928e75a5cdb85cecd7f6d6c72cd 189 Pfam PF13302 Acetyltransferase (GNAT) domain 15 144 2.8E-17 T 14-10-2018 IPR000182 GNAT domain Theos_1702 1660d8cbe6b0608c05d29ac1ef4d4b7c 149 Pfam PF10722 Putative bacterial sensory transduction regulator 26 144 2.9E-17 T 14-10-2018 IPR019660 Putative sensory transduction regulator YbjN Theos_0470 2fe554a9516c5d08e27e75126a43540f 283 Gene3D G3DSA:3.90.550.10 1 213 9.6E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_0470 2fe554a9516c5d08e27e75126a43540f 283 Pfam PF00535 Glycosyl transferase family 2 4 99 1.8E-17 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Theos_0470 2fe554a9516c5d08e27e75126a43540f 283 SUPERFAMILY SSF53448 1 244 8.63E-40 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1332 696a65944849221ac05ad4f25fa96595 274 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 231 257 - T 14-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 Theos_1332 696a65944849221ac05ad4f25fa96595 274 Pfam PF01148 Cytidylyltransferase family 8 273 3.4E-58 T 14-10-2018 Theos_2323 9edd7d696f6c096570b4b1a98993c77b 368 SUPERFAMILY SSF52833 280 364 1.68E-14 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_2323 9edd7d696f6c096570b4b1a98993c77b 368 SUPERFAMILY SSF53800 3 231 1.42E-34 T 14-10-2018 Theos_2323 9edd7d696f6c096570b4b1a98993c77b 368 Gene3D G3DSA:3.40.50.1400 116 233 1.9E-15 T 14-10-2018 Theos_2323 9edd7d696f6c096570b4b1a98993c77b 368 Gene3D G3DSA:3.40.50.1400 1 115 5.8E-24 T 14-10-2018 Theos_2323 9edd7d696f6c096570b4b1a98993c77b 368 Gene3D G3DSA:3.40.30.10 277 367 6.2E-15 T 14-10-2018 Theos_2323 9edd7d696f6c096570b4b1a98993c77b 368 Pfam PF01903 CbiX 8 109 2.8E-18 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 Theos_2323 9edd7d696f6c096570b4b1a98993c77b 368 Pfam PF01903 CbiX 128 221 1.3E-7 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 Theos_0409 5a1f74a42544bb1c6e6276b88ba4e2be 207 SUPERFAMILY SSF56281 9 198 2.1E-54 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_0409 5a1f74a42544bb1c6e6276b88ba4e2be 207 Pfam PF00753 Metallo-beta-lactamase superfamily 9 184 1.8E-32 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0409 5a1f74a42544bb1c6e6276b88ba4e2be 207 SMART SM00849 12 184 7.0E-41 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0409 5a1f74a42544bb1c6e6276b88ba4e2be 207 Gene3D G3DSA:3.60.15.10 1 207 2.5E-82 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1626 cdcaecf8ad35ea70e910875e0d0f181b 144 Gene3D G3DSA:3.40.30.10 25 143 3.2E-31 T 14-10-2018 Theos_1626 cdcaecf8ad35ea70e910875e0d0f181b 144 SUPERFAMILY SSF52833 14 139 3.28E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_1626 cdcaecf8ad35ea70e910875e0d0f181b 144 SMART SM00594 19 134 8.0E-4 T 14-10-2018 IPR006577 UAS Theos_1626 cdcaecf8ad35ea70e910875e0d0f181b 144 Pfam PF13899 Thioredoxin-like 27 109 7.3E-12 T 14-10-2018 Theos_1207 ceeb169a005a54b72090311155b974f8 261 Pfam PF04085 rod shape-determining protein MreC 114 258 2.0E-29 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 Theos_1207 ceeb169a005a54b72090311155b974f8 261 Gene3D G3DSA:2.40.10.340 112 257 2.0E-28 T 14-10-2018 Theos_1207 ceeb169a005a54b72090311155b974f8 261 PIRSF PIRSF038471 2 261 1.9E-41 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 Theos_1207 ceeb169a005a54b72090311155b974f8 261 Gene3D G3DSA:2.40.10.350 171 246 2.0E-28 T 14-10-2018 Theos_0733 d234684de74e4653daef03526dc2a4c2 378 SUPERFAMILY SSF56801 80 320 9.81E-25 T 14-10-2018 Theos_0733 d234684de74e4653daef03526dc2a4c2 378 Gene3D G3DSA:3.40.50.12780 2 291 2.0E-54 T 14-10-2018 Theos_0733 d234684de74e4653daef03526dc2a4c2 378 Pfam PF00501 AMP-binding enzyme 105 253 8.7E-6 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Theos_1581 0a7b00090cc612e83e8954755baa9bcc 227 Pfam PF00106 short chain dehydrogenase 5 187 2.1E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Theos_1581 0a7b00090cc612e83e8954755baa9bcc 227 SUPERFAMILY SSF51735 2 215 2.86E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_1581 0a7b00090cc612e83e8954755baa9bcc 227 Gene3D G3DSA:3.40.50.720 1 221 1.0E-39 T 14-10-2018 Theos_1095 285c377f2ccd91ff34b78cdc53e08d93 300 Pfam PF03547 Membrane transport protein 158 292 7.4E-19 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Theos_1095 285c377f2ccd91ff34b78cdc53e08d93 300 Pfam PF03547 Membrane transport protein 8 137 2.6E-9 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Theos_2464 9eed023517d25c5a60de1c33ee876107 414 SUPERFAMILY SSF53850 23 404 5.65E-81 T 14-10-2018 Theos_2464 9eed023517d25c5a60de1c33ee876107 414 Gene3D G3DSA:3.40.190.10 20 412 6.7E-92 T 14-10-2018 Theos_2464 9eed023517d25c5a60de1c33ee876107 414 Pfam PF13416 Bacterial extracellular solute-binding protein 42 347 8.4E-45 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_2487 d9b04f42647530faee2d54d5e9529998 672 SMART SM00487 37 282 1.0E-9 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Theos_2487 d9b04f42647530faee2d54d5e9529998 672 SUPERFAMILY SSF52540 220 581 2.95E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2487 d9b04f42647530faee2d54d5e9529998 672 SUPERFAMILY SSF52540 23 292 1.54E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2487 d9b04f42647530faee2d54d5e9529998 672 Gene3D G3DSA:3.40.50.300 412 580 7.4E-22 T 14-10-2018 Theos_2487 d9b04f42647530faee2d54d5e9529998 672 Pfam PF00271 Helicase conserved C-terminal domain 437 550 1.0E-6 T 14-10-2018 IPR001650 Helicase, C-terminal Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 SUPERFAMILY SSF52821 160 283 6.81E-40 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 Pfam PF00581 Rhodanese-like domain 163 273 3.8E-20 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 Pfam PF00581 Rhodanese-like domain 11 120 9.7E-16 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 Gene3D G3DSA:3.40.250.10 1 143 8.7E-47 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 ProSitePatterns PS00683 Rhodanese C-terminal signature. 262 272 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 SMART SM00450 151 278 8.2E-25 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 SMART SM00450 10 124 7.3E-20 T 14-10-2018 IPR001763 Rhodanese-like domain Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 ProSitePatterns PS00380 Rhodanese signature 1. 36 47 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 SUPERFAMILY SSF52821 3 143 3.01E-42 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0907 70e8af4abbbdef2e6c2a2363d36cbe3a 285 Gene3D G3DSA:3.40.250.10 144 285 1.6E-49 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_0332 96a8eece419a2430f251b4406b186af5 407 SUPERFAMILY SSF53383 7 407 3.81E-180 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0332 96a8eece419a2430f251b4406b186af5 407 PIRSF PIRSF000412 3 404 2.3E-174 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Theos_0332 96a8eece419a2430f251b4406b186af5 407 Gene3D G3DSA:3.90.1150.10 8 387 2.0E-187 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0332 96a8eece419a2430f251b4406b186af5 407 Pfam PF00464 Serine hydroxymethyltransferase 7 381 5.4E-173 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Theos_0332 96a8eece419a2430f251b4406b186af5 407 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 406 52.638 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Theos_0332 96a8eece419a2430f251b4406b186af5 407 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Theos_0332 96a8eece419a2430f251b4406b186af5 407 Gene3D G3DSA:3.40.640.10 33 284 2.0E-187 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0159 b7cdfca07c3a004a9ea309dfb5d88c12 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 250 4.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0159 b7cdfca07c3a004a9ea309dfb5d88c12 260 SUPERFAMILY SSF161098 3 252 5.79E-50 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0159 b7cdfca07c3a004a9ea309dfb5d88c12 260 Gene3D G3DSA:1.10.3720.10 1 251 3.3E-51 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2344 59cf5cdaa9422697e264c7e22c88e76a 241 SUPERFAMILY SSF51658 24 227 2.49E-28 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily Theos_2344 59cf5cdaa9422697e264c7e22c88e76a 241 Gene3D G3DSA:3.20.20.150 3 238 2.6E-54 T 14-10-2018 Theos_2344 59cf5cdaa9422697e264c7e22c88e76a 241 Pfam PF01261 Xylose isomerase-like TIM barrel 54 203 8.3E-15 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Theos_1620 277ff8ad64289dd0fbef374a8b281aea 186 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 100 178 1.6E-23 T 14-10-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX Theos_1620 277ff8ad64289dd0fbef374a8b281aea 186 Pfam PF00034 Cytochrome c 89 177 1.7E-4 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1620 277ff8ad64289dd0fbef374a8b281aea 186 SUPERFAMILY SSF46626 11 177 3.76E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1620 277ff8ad64289dd0fbef374a8b281aea 186 Gene3D G3DSA:1.10.760.10 22 185 1.5E-50 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1620 277ff8ad64289dd0fbef374a8b281aea 186 PIRSF PIRSF024608 1 185 1.3E-76 T 14-10-2018 IPR016823 Sulfur oxidation c-type cytochrome SoxX, type II Theos_0531 b440461a0306658fc1a7506f0b4a48e3 360 Pfam PF00953 Glycosyl transferase family 4 95 246 9.2E-33 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 Theos_2437 ed75b820b385d357b21af42a30301789 339 Pfam PF02321 Outer membrane efflux protein 229 330 2.1E-5 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Theos_2437 ed75b820b385d357b21af42a30301789 339 Pfam PF02321 Outer membrane efflux protein 63 153 9.0E-12 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Theos_2437 ed75b820b385d357b21af42a30301789 339 SUPERFAMILY SSF56954 4 333 1.2E-40 T 14-10-2018 Theos_2437 ed75b820b385d357b21af42a30301789 339 Gene3D G3DSA:1.20.1600.10 12 227 4.5E-28 T 14-10-2018 Theos_2437 ed75b820b385d357b21af42a30301789 339 Gene3D G3DSA:1.20.1600.10 228 334 9.5E-11 T 14-10-2018 Theos_1037 ef29a304449fe70c072c6b99ac9b39d6 443 SUPERFAMILY SSF103473 11 429 2.09E-62 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1037 ef29a304449fe70c072c6b99ac9b39d6 443 Gene3D G3DSA:1.20.1250.20 213 430 3.8E-58 T 14-10-2018 Theos_1037 ef29a304449fe70c072c6b99ac9b39d6 443 Gene3D G3DSA:1.20.1250.20 4 203 4.4E-48 T 14-10-2018 Theos_1037 ef29a304449fe70c072c6b99ac9b39d6 443 Pfam PF07690 Major Facilitator Superfamily 24 310 9.5E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_2134 d9dd9560b090bb865c56c6f44b604a78 488 SUPERFAMILY SSF53474 2 459 1.33E-98 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_2134 d9dd9560b090bb865c56c6f44b604a78 488 Gene3D G3DSA:3.40.50.1820 1 470 3.0E-116 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_2134 d9dd9560b090bb865c56c6f44b604a78 488 Pfam PF00135 Carboxylesterase family 11 463 4.1E-82 T 14-10-2018 IPR002018 Carboxylesterase, type B Theos_2134 d9dd9560b090bb865c56c6f44b604a78 488 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 165 180 - T 14-10-2018 IPR019826 Carboxylesterase type B, active site Theos_1583 c849355efabe3bc3d120d41ec8d4c1e1 130 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 114 2.0E-24 T 14-10-2018 Theos_1583 c849355efabe3bc3d120d41ec8d4c1e1 130 Gene3D G3DSA:3.10.180.10 1 129 4.7E-39 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_1583 c849355efabe3bc3d120d41ec8d4c1e1 130 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 2 129 4.7E-37 T 14-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 Theos_1583 c849355efabe3bc3d120d41ec8d4c1e1 130 SUPERFAMILY SSF54593 1 129 4.4E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Theos_1752 ac4315483e50ab6caf56d19d09f73965 578 Gene3D G3DSA:3.40.50.300 360 572 1.4E-35 T 14-10-2018 Theos_1752 ac4315483e50ab6caf56d19d09f73965 578 SMART SM00382 398 575 3.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1752 ac4315483e50ab6caf56d19d09f73965 578 SUPERFAMILY SSF52540 385 568 1.22E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1752 ac4315483e50ab6caf56d19d09f73965 578 Pfam PF00005 ABC transporter 389 515 3.4E-16 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1752 ac4315483e50ab6caf56d19d09f73965 578 SUPERFAMILY SSF55729 97 377 2.57E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_1752 ac4315483e50ab6caf56d19d09f73965 578 Pfam PF00583 Acetyltransferase (GNAT) family 169 291 9.4E-8 T 14-10-2018 IPR000182 GNAT domain Theos_0901 4abd99b5633df5c6337c8d36a9d7889c 72 Hamap MF_00088 UPF0109 protein . 1 72 18.524 T 14-10-2018 IPR020627 Uncharacterised protein family UPF0109 Theos_0901 4abd99b5633df5c6337c8d36a9d7889c 72 Gene3D G3DSA:3.30.300.20 4 70 1.6E-9 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Theos_0901 4abd99b5633df5c6337c8d36a9d7889c 72 Pfam PF13083 KH domain 2 66 5.3E-19 T 14-10-2018 Theos_0901 4abd99b5633df5c6337c8d36a9d7889c 72 SUPERFAMILY SSF54814 6 61 4.32E-8 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Theos_0709 c2426d5378d5d182b85ca8530627d954 364 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 8 330 23.735 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0709 c2426d5378d5d182b85ca8530627d954 364 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 217 230 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0709 c2426d5378d5d182b85ca8530627d954 364 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 54 69 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0709 c2426d5378d5d182b85ca8530627d954 364 Pfam PF00146 NADH dehydrogenase 15 324 4.0E-117 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 Pfam PF00334 Nucleoside diphosphate kinase 2 135 2.4E-58 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 SUPERFAMILY SSF54919 1 136 1.2E-58 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 SMART SM00562 1 137 1.7E-86 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 6.2E-50 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 6.2E-50 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 6.2E-50 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 6.2E-50 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 6.2E-50 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 37.38 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2156 453d8269b9bd0acd29bd795bab9fe27f 137 Gene3D G3DSA:3.30.70.141 1 137 8.1E-62 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Theos_2066 5fed8ceca62a5041036f516cc1d6a0ff 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 2.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_2066 5fed8ceca62a5041036f516cc1d6a0ff 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 2.0E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_2066 5fed8ceca62a5041036f516cc1d6a0ff 201 SUPERFAMILY SSF46689 21 97 9.71E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_2066 5fed8ceca62a5041036f516cc1d6a0ff 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 1.4E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_2066 5fed8ceca62a5041036f516cc1d6a0ff 201 Gene3D G3DSA:1.10.357.10 15 201 9.1E-73 T 14-10-2018 Theos_2066 5fed8ceca62a5041036f516cc1d6a0ff 201 SUPERFAMILY SSF48498 102 177 7.12E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Theos_1105 d4e8a970bf28da9dc4b2ebe6cd6d25d8 132 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 30 126 1.0E-18 T 14-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 Theos_1105 d4e8a970bf28da9dc4b2ebe6cd6d25d8 132 SUPERFAMILY SSF81593 7 126 3.92E-28 T 14-10-2018 Theos_1105 d4e8a970bf28da9dc4b2ebe6cd6d25d8 132 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 6 127 3.8E-29 T 14-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 Theos_1105 d4e8a970bf28da9dc4b2ebe6cd6d25d8 132 Gene3D G3DSA:1.20.120.330 10 128 3.0E-40 T 14-10-2018 Theos_0876 b24b405ccefd5f8de44770f4968960c4 230 PIRSF PIRSF033094 1 227 3.0E-89 T 14-10-2018 IPR014578 Predicted phosphoesterase, CT488 type Theos_0876 b24b405ccefd5f8de44770f4968960c4 230 SUPERFAMILY SSF56300 1 208 3.62E-25 T 14-10-2018 Theos_0876 b24b405ccefd5f8de44770f4968960c4 230 Pfam PF00149 Calcineurin-like phosphoesterase 1 193 5.9E-10 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Theos_0629 2d933c5e222cdefbdb5a34a5a1044377 295 Gene3D G3DSA:3.40.50.720 86 267 9.6E-74 T 14-10-2018 Theos_0629 2d933c5e222cdefbdb5a34a5a1044377 295 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 201 217 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Theos_0629 2d933c5e222cdefbdb5a34a5a1044377 295 SUPERFAMILY SSF51735 88 261 3.33E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0629 2d933c5e222cdefbdb5a34a5a1044377 295 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 94 260 8.7E-45 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Theos_0629 2d933c5e222cdefbdb5a34a5a1044377 295 Gene3D G3DSA:3.40.50.720 53 295 9.6E-74 T 14-10-2018 Theos_1021 9f3dc9d7103cd9dff2ebb28ea6a7bb3b 462 Pfam PF00395 S-layer homology domain 33 62 0.0014 T 14-10-2018 IPR001119 S-layer homology domain Theos_1021 9f3dc9d7103cd9dff2ebb28ea6a7bb3b 462 Pfam PF00395 S-layer homology domain 147 184 6.0E-7 T 14-10-2018 IPR001119 S-layer homology domain Theos_1021 9f3dc9d7103cd9dff2ebb28ea6a7bb3b 462 Pfam PF00395 S-layer homology domain 80 123 2.7E-4 T 14-10-2018 IPR001119 S-layer homology domain Theos_1244 7267f709027ee70cb2c739afed22a027 188 SUPERFAMILY SSF52980 12 183 8.04E-28 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_1244 7267f709027ee70cb2c739afed22a027 188 Pfam PF05685 Putative restriction endonuclease 17 173 3.0E-32 T 14-10-2018 IPR008538 Domain of unknown function DUF820 Theos_1244 7267f709027ee70cb2c739afed22a027 188 Gene3D G3DSA:3.90.1570.10 7 185 6.2E-19 T 14-10-2018 Theos_0704 8f32629d799e96621512398b478e68f9 469 Pfam PF00361 Proton-conducting membrane transporter 112 399 4.4E-47 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0704 8f32629d799e96621512398b478e68f9 469 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 23 462 4.2E-113 T 14-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0704 8f32629d799e96621512398b478e68f9 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 359 385 1.2E-25 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0704 8f32629d799e96621512398b478e68f9 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 118 137 1.2E-25 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0704 8f32629d799e96621512398b478e68f9 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 148 172 1.2E-25 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0704 8f32629d799e96621512398b478e68f9 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 307 326 1.2E-25 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0704 8f32629d799e96621512398b478e68f9 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 219 243 1.2E-25 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_0771 0dc48b58c3875f4604672189639796f1 334 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 116 4.8E-29 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Theos_0771 0dc48b58c3875f4604672189639796f1 334 SUPERFAMILY SSF51735 4 155 1.64E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Theos_0771 0dc48b58c3875f4604672189639796f1 334 SUPERFAMILY SSF55347 127 318 7.37E-73 T 14-10-2018 Theos_0771 0dc48b58c3875f4604672189639796f1 334 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 5 331 3.5E-121 T 14-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Theos_0771 0dc48b58c3875f4604672189639796f1 334 PIRSF PIRSF000148 3 333 4.2E-122 T 14-10-2018 Theos_0771 0dc48b58c3875f4604672189639796f1 334 Gene3D G3DSA:3.30.360.10 126 314 5.9E-144 T 14-10-2018 Theos_0771 0dc48b58c3875f4604672189639796f1 334 SMART SM00859 5 119 8.9E-40 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Theos_0771 0dc48b58c3875f4604672189639796f1 334 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 3 331 35.909 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Theos_0771 0dc48b58c3875f4604672189639796f1 334 Gene3D G3DSA:3.40.50.720 6 328 5.9E-144 T 14-10-2018 Theos_0771 0dc48b58c3875f4604672189639796f1 334 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 137 317 5.7E-53 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Theos_0437 c91f4bf1bab12cf0cbafb88212e61814 205 Pfam PF04350 Pilus assembly protein, PilO 47 184 3.3E-6 T 14-10-2018 IPR007445 Pilus assembly protein, PilO Theos_1036 37f2b688a1a2764c09e0e1e484966953 443 Pfam PF07690 Major Facilitator Superfamily 39 333 2.1E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_1036 37f2b688a1a2764c09e0e1e484966953 443 SUPERFAMILY SSF103473 12 434 4.45E-43 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_1036 37f2b688a1a2764c09e0e1e484966953 443 Gene3D G3DSA:1.20.1250.20 234 442 8.7E-62 T 14-10-2018 Theos_1036 37f2b688a1a2764c09e0e1e484966953 443 Gene3D G3DSA:1.20.1250.20 2 233 1.6E-66 T 14-10-2018 Theos_1036 37f2b688a1a2764c09e0e1e484966953 443 TIGRFAM TIGR00886 2A0108: nitrite transporter 28 394 1.5E-100 T 14-10-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 Theos_0508 0381de83cf861e9cae7665a30e18acf1 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 305 8.8E-42 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0508 0381de83cf861e9cae7665a30e18acf1 306 SUPERFAMILY SSF161098 91 289 2.13E-21 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0508 0381de83cf861e9cae7665a30e18acf1 306 Gene3D G3DSA:1.10.3720.10 87 299 1.4E-26 T 14-10-2018 IPR035906 MetI-like superfamily Theos_2399 36bb1cd2b8d8393f84b5020d8cc0156a 205 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 123 136 - T 14-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Theos_2399 36bb1cd2b8d8393f84b5020d8cc0156a 205 SUPERFAMILY SSF51569 7 185 1.81E-55 T 14-10-2018 Theos_2399 36bb1cd2b8d8393f84b5020d8cc0156a 205 Pfam PF01081 KDPG and KHG aldolase 6 185 7.6E-57 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Theos_2399 36bb1cd2b8d8393f84b5020d8cc0156a 205 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 7 186 8.6E-61 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Theos_2399 36bb1cd2b8d8393f84b5020d8cc0156a 205 Gene3D G3DSA:3.20.20.70 4 203 1.2E-65 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0778 ff2dc27cca2efc9706421192b442e293 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 14-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_0778 ff2dc27cca2efc9706421192b442e293 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 6.6E-23 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Theos_0778 ff2dc27cca2efc9706421192b442e293 65 SUPERFAMILY SSF143034 2 64 9.81E-20 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0778 ff2dc27cca2efc9706421192b442e293 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 15.702 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Theos_0778 ff2dc27cca2efc9706421192b442e293 65 Gene3D G3DSA:2.40.50.530 1 65 1.9E-29 T 14-10-2018 Theos_0778 ff2dc27cca2efc9706421192b442e293 65 Pfam PF01632 Ribosomal protein L35 2 62 4.2E-21 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0778 ff2dc27cca2efc9706421192b442e293 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 9.0E-9 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Theos_0778 ff2dc27cca2efc9706421192b442e293 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 9.0E-9 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Theos_0778 ff2dc27cca2efc9706421192b442e293 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 9.0E-9 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Theos_2406 290b7f016b2b63f7cfeb089aedebeac1 424 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 5 414 1.1E-90 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Theos_2406 290b7f016b2b63f7cfeb089aedebeac1 424 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 15 420 6.7E-116 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Theos_2406 290b7f016b2b63f7cfeb089aedebeac1 424 PIRSF PIRSF006066 1 424 2.2E-109 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Theos_2078 b7cf3438cba9891f4efee1403e848e02 230 Pfam PF12804 MobA-like NTP transferase domain 3 158 4.9E-16 T 14-10-2018 IPR025877 MobA-like NTP transferase Theos_2078 b7cf3438cba9891f4efee1403e848e02 230 SUPERFAMILY SSF53448 3 228 1.2E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_2078 b7cf3438cba9891f4efee1403e848e02 230 Gene3D G3DSA:3.90.550.10 1 230 1.9E-74 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1833 07617a6d8420b328750cd86b6dd89d3f 339 Pfam PF00005 ABC transporter 27 190 2.5E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1833 07617a6d8420b328750cd86b6dd89d3f 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 329 2.7E-22 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Theos_1833 07617a6d8420b328750cd86b6dd89d3f 339 SMART SM00382 35 240 1.6E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1833 07617a6d8420b328750cd86b6dd89d3f 339 Gene3D G3DSA:3.40.50.300 4 339 1.3E-98 T 14-10-2018 Theos_1833 07617a6d8420b328750cd86b6dd89d3f 339 SUPERFAMILY SSF52540 6 261 1.16E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1833 07617a6d8420b328750cd86b6dd89d3f 339 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1833 07617a6d8420b328750cd86b6dd89d3f 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 308 5.4E-16 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Theos_0539 304ec9ecb49e0df1bb701173221fb588 185 Pfam PF12804 MobA-like NTP transferase domain 4 156 1.1E-32 T 14-10-2018 IPR025877 MobA-like NTP transferase Theos_0539 304ec9ecb49e0df1bb701173221fb588 185 SUPERFAMILY SSF53448 2 184 2.48E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_0539 304ec9ecb49e0df1bb701173221fb588 185 Gene3D G3DSA:3.90.550.10 2 185 3.6E-40 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_0647 c329fcffa91e070ab4e0bdc86d826645 378 SUPERFAMILY SSF103473 11 372 1.44E-31 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_0647 c329fcffa91e070ab4e0bdc86d826645 378 Pfam PF07690 Major Facilitator Superfamily 215 371 4.0E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_0647 c329fcffa91e070ab4e0bdc86d826645 378 Gene3D G3DSA:1.20.1250.20 212 374 2.1E-16 T 14-10-2018 Theos_0647 c329fcffa91e070ab4e0bdc86d826645 378 Gene3D G3DSA:1.20.1250.20 4 180 2.7E-8 T 14-10-2018 Theos_2415 ef3958bbf3a39389ddf4519ee51995a5 205 Gene3D G3DSA:3.40.50.1010 1 181 2.5E-17 T 14-10-2018 Theos_2415 ef3958bbf3a39389ddf4519ee51995a5 205 Pfam PF01936 NYN domain 4 173 1.5E-13 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type Theos_2003 b555b9b4aac9ffc9490f353c281c1aea 77 SUPERFAMILY SSF143120 2 42 3.4E-7 T 14-10-2018 IPR036165 YefM-like superfamily Theos_2003 b555b9b4aac9ffc9490f353c281c1aea 77 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 41 1.6E-5 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Theos_0696 5ddf17cee1f05fa6d07a110bb27b5bf1 372 Pfam PF00999 Sodium/hydrogen exchanger family 14 347 3.0E-32 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Theos_0696 5ddf17cee1f05fa6d07a110bb27b5bf1 372 Gene3D G3DSA:1.20.1530.20 4 359 1.4E-41 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily Theos_0637 51ed499faff0a40ba41d550e30564079 152 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 71 145 1.6E-23 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Theos_0637 51ed499faff0a40ba41d550e30564079 152 Gene3D G3DSA:1.10.10.10 67 149 2.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0637 51ed499faff0a40ba41d550e30564079 152 SUPERFAMILY SSF53155 2 65 5.89E-5 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Theos_0637 51ed499faff0a40ba41d550e30564079 152 SUPERFAMILY SSF46767 68 146 7.32E-23 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 Theos_0637 51ed499faff0a40ba41d550e30564079 152 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 71 144 5.2E-21 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Theos_0605 69c89467414a1f24287f7092fa3ef52a 210 Pfam PF00571 CBS domain 77 130 1.8E-14 T 14-10-2018 IPR000644 CBS domain Theos_0605 69c89467414a1f24287f7092fa3ef52a 210 Pfam PF00571 CBS domain 3 56 1.3E-16 T 14-10-2018 IPR000644 CBS domain Theos_0605 69c89467414a1f24287f7092fa3ef52a 210 Gene3D G3DSA:3.10.580.10 1 142 6.7E-42 T 14-10-2018 Theos_0605 69c89467414a1f24287f7092fa3ef52a 210 SUPERFAMILY SSF54631 1 132 6.44E-38 T 14-10-2018 Theos_0605 69c89467414a1f24287f7092fa3ef52a 210 SMART SM00116 10 57 2.5E-14 T 14-10-2018 IPR000644 CBS domain Theos_0605 69c89467414a1f24287f7092fa3ef52a 210 SMART SM00116 84 131 3.7E-12 T 14-10-2018 IPR000644 CBS domain Theos_1496 003ced47c2315a698c9428c406e2e58b 196 Gene3D G3DSA:3.40.50.300 1 196 2.9E-91 T 14-10-2018 Theos_1496 003ced47c2315a698c9428c406e2e58b 196 SUPERFAMILY SSF52540 10 189 2.19E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1496 003ced47c2315a698c9428c406e2e58b 196 Pfam PF00025 ADP-ribosylation factor family 66 185 4.5E-6 T 14-10-2018 IPR006689 Small GTPase superfamily, ARF/SAR type GO:0005525 Theos_0246 45f31f66ad4252f424b139b8f579718b 293 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 196 230 5.1E-5 T 14-10-2018 IPR001451 Hexapeptide repeat Theos_0246 45f31f66ad4252f424b139b8f579718b 293 Gene3D G3DSA:2.160.10.10 93 252 1.2E-36 T 14-10-2018 Theos_0246 45f31f66ad4252f424b139b8f579718b 293 SUPERFAMILY SSF51161 104 249 4.57E-38 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Theos_0963 48a7b5c322d64c84db12c08f04f53225 398 Pfam PF12704 MacB-like periplasmic core domain 22 227 6.3E-10 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Theos_0806 4690c346421acc867c713cff3737126f 964 Pfam PF13558 Putative exonuclease SbcCD, C subunit 863 924 4.9E-11 T 14-10-2018 Theos_0806 4690c346421acc867c713cff3737126f 964 SUPERFAMILY SSF52540 3 959 1.47E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0806 4690c346421acc867c713cff3737126f 964 Pfam PF13476 AAA domain 5 201 3.1E-24 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain Theos_0806 4690c346421acc867c713cff3737126f 964 Gene3D G3DSA:3.40.50.300 729 963 9.8E-31 T 14-10-2018 Theos_0806 4690c346421acc867c713cff3737126f 964 Gene3D G3DSA:3.40.50.300 2 342 2.4E-40 T 14-10-2018 Theos_2086 2aaed909a63b06fd3abaaf5a781cb37a 81 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 58 6.0E-11 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 Theos_2086 2aaed909a63b06fd3abaaf5a781cb37a 81 Pfam PF12728 Helix-turn-helix domain 8 59 6.3E-14 T 14-10-2018 Theos_2471 65ce3989fbd27065d396e5675170477a 234 SUPERFAMILY SSF56529 5 222 3.51E-38 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Theos_2471 65ce3989fbd27065d396e5675170477a 234 Gene3D G3DSA:3.90.850.10 2 229 6.7E-47 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Theos_1723 b5fb75f596b2e96fdc4625dbb2d2f79b 476 SUPERFAMILY SSF53448 60 363 1.69E-52 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1723 b5fb75f596b2e96fdc4625dbb2d2f79b 476 Gene3D G3DSA:3.90.550.10 48 315 1.3E-43 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1723 b5fb75f596b2e96fdc4625dbb2d2f79b 476 Pfam PF13641 Glycosyltransferase like family 2 61 325 1.0E-28 T 14-10-2018 Theos_0355 60c4deeaa78a5f875633f5d753d1e45d 738 SUPERFAMILY SSF52540 4 453 1.84E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 SUPERFAMILY SSF53807 17 285 1.08E-58 T 14-10-2018 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 PRINTS PR00691 Adhesin B signature 17 38 3.9E-15 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 PRINTS PR00691 Adhesin B signature 61 80 3.9E-15 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 PRINTS PR00691 Adhesin B signature 122 141 3.9E-15 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 PRINTS PR00691 Adhesin B signature 42 60 3.9E-15 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 Gene3D G3DSA:3.40.50.1980 183 286 8.5E-11 T 14-10-2018 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 Pfam PF01297 Zinc-uptake complex component A periplasmic 21 284 4.7E-52 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 PRINTS PR00690 Adhesin family signature 17 35 5.0E-11 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 PRINTS PR00690 Adhesin family signature 48 61 5.0E-11 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 PRINTS PR00690 Adhesin family signature 61 78 5.0E-11 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 PRINTS PR00690 Adhesin family signature 177 198 5.0E-11 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Theos_2379 3718d0709d6c27688ffce51e63d5819f 290 Gene3D G3DSA:3.40.50.1980 17 179 2.2E-36 T 14-10-2018 Theos_0780 c8e43e83d8feaf1770438bbffbd0fcc1 153 Pfam PF06695 Putative small multi-drug export protein 16 136 5.8E-34 T 14-10-2018 IPR009577 Putative small multi-drug export Theos_0861 19fa27b87fd18de3677d47686be89c23 241 Gene3D G3DSA:3.40.50.300 1 228 2.1E-67 T 14-10-2018 Theos_0861 19fa27b87fd18de3677d47686be89c23 241 SUPERFAMILY SSF52540 1 223 7.01E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0861 19fa27b87fd18de3677d47686be89c23 241 Pfam PF00005 ABC transporter 20 166 1.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_0861 19fa27b87fd18de3677d47686be89c23 241 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_0861 19fa27b87fd18de3677d47686be89c23 241 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 1.4E-80 T 14-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 Theos_0861 19fa27b87fd18de3677d47686be89c23 241 SMART SM00382 28 214 6.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1326 4776b85105710c6ad79ed29dad92c8de 394 SUPERFAMILY SSF56349 72 378 3.83E-66 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Theos_1326 4776b85105710c6ad79ed29dad92c8de 394 Pfam PF00589 Phage integrase family 189 373 2.8E-24 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Theos_1326 4776b85105710c6ad79ed29dad92c8de 394 Gene3D G3DSA:1.10.150.130 68 186 4.1E-22 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Theos_1326 4776b85105710c6ad79ed29dad92c8de 394 Gene3D G3DSA:1.10.443.10 189 387 1.4E-47 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Theos_0114 b2d5c7cabacba6d48aeda0890e926929 920 SUPERFAMILY SSF48452 506 714 5.06E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0114 b2d5c7cabacba6d48aeda0890e926929 920 Gene3D G3DSA:1.25.40.10 619 835 2.3E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0114 b2d5c7cabacba6d48aeda0890e926929 920 Gene3D G3DSA:1.25.40.10 411 616 1.2E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0979 b1716da3c158d5cb2535462cb7bc4ff6 129 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 2 112 4.6E-40 T 14-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 Theos_0979 b1716da3c158d5cb2535462cb7bc4ff6 129 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 2 110 8.9E-19 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 Theos_0979 b1716da3c158d5cb2535462cb7bc4ff6 129 Pfam PF03061 Thioesterase superfamily 30 99 1.3E-15 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Theos_0979 b1716da3c158d5cb2535462cb7bc4ff6 129 Gene3D G3DSA:3.10.129.10 1 112 7.7E-41 T 14-10-2018 Theos_0979 b1716da3c158d5cb2535462cb7bc4ff6 129 SUPERFAMILY SSF54637 2 111 9.12E-28 T 14-10-2018 IPR029069 HotDog domain superfamily Theos_1465 98dd2866d8d427f51eac88e4eab51a1f 223 SUPERFAMILY SSF51569 1 221 1.15E-72 T 14-10-2018 Theos_1465 98dd2866d8d427f51eac88e4eab51a1f 223 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 208 1.6E-56 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 Theos_1465 98dd2866d8d427f51eac88e4eab51a1f 223 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 221 2.7E-83 T 14-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Theos_1465 98dd2866d8d427f51eac88e4eab51a1f 223 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 Theos_1465 98dd2866d8d427f51eac88e4eab51a1f 223 ProSitePatterns PS00958 Transaldolase active site. 89 106 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 Theos_1465 98dd2866d8d427f51eac88e4eab51a1f 223 Hamap MF_00494 Probable transaldolase [tal]. 1 223 43.83 T 14-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Theos_1465 98dd2866d8d427f51eac88e4eab51a1f 223 Gene3D G3DSA:3.20.20.70 1 223 9.7E-92 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1592 f15f8e277cb035a815d15257e725f6a1 158 Pfam PF04306 Protein of unknown function (DUF456) 21 155 2.4E-29 T 14-10-2018 IPR007403 Protein of unknown function DUF456 Theos_1522 b661c51964ceee23eda0d34b6dcc6330 133 Gene3D G3DSA:3.40.50.1010 5 130 2.4E-15 T 14-10-2018 Theos_1522 b661c51964ceee23eda0d34b6dcc6330 133 Pfam PF01850 PIN domain 6 125 1.9E-16 T 14-10-2018 IPR002716 PIN domain Theos_1522 b661c51964ceee23eda0d34b6dcc6330 133 SUPERFAMILY SSF88723 5 131 1.04E-21 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_1522 b661c51964ceee23eda0d34b6dcc6330 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 133 10.662 T 14-10-2018 IPR022907 VapC family GO:0004540 Theos_1720 4732c27bafd1c0ac84ac3cc3cdad94ac 571 Gene3D G3DSA:3.50.50.60 16 176 5.6E-12 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1720 4732c27bafd1c0ac84ac3cc3cdad94ac 571 SUPERFAMILY SSF51905 17 407 7.6E-20 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1720 4732c27bafd1c0ac84ac3cc3cdad94ac 571 Pfam PF12831 FAD dependent oxidoreductase 19 410 5.6E-75 T 14-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal Theos_1274 f84f6b4047c473ee3549d2b5f79564d7 141 Pfam PF09390 Protein of unknown function (DUF1999) 24 139 3.0E-31 T 14-10-2018 IPR018987 Protein of unknown function DUF1999 Theos_1274 f84f6b4047c473ee3549d2b5f79564d7 141 Gene3D G3DSA:3.40.630.30 1 141 5.6E-64 T 14-10-2018 Theos_1274 f84f6b4047c473ee3549d2b5f79564d7 141 SUPERFAMILY SSF55729 1 130 1.06E-47 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_1708 12f545cf960e2a4f57e7d2c589d3aa81 122 SUPERFAMILY SSF53474 4 88 5.15E-15 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1708 12f545cf960e2a4f57e7d2c589d3aa81 122 Gene3D G3DSA:3.40.50.12270 1 121 2.2E-49 T 14-10-2018 Theos_1371 b42acf7c415d8be5730b53cdce271476 557 Pfam PF09818 Predicted ATPase of the ABC class 6 429 5.4E-155 T 14-10-2018 IPR019195 ABC transporter, ATPase, putative Theos_1371 b42acf7c415d8be5730b53cdce271476 557 SUPERFAMILY SSF52540 222 412 2.9E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1578 211999db872e19c60d5c533863fae5b4 346 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 342 5.1E-64 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Theos_1595 4430f0521a425fbf9f1967721d47a37f 247 Pfam PF02146 Sir2 family 21 195 3.7E-46 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 Theos_1595 4430f0521a425fbf9f1967721d47a37f 247 SUPERFAMILY SSF52467 3 239 3.74E-82 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Theos_1595 4430f0521a425fbf9f1967721d47a37f 247 Gene3D G3DSA:3.40.50.1220 12 236 1.4E-81 T 14-10-2018 Theos_1595 4430f0521a425fbf9f1967721d47a37f 247 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 14 245 59.517 T 14-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 Theos_1595 4430f0521a425fbf9f1967721d47a37f 247 Gene3D G3DSA:3.30.1600.10 30 165 1.4E-81 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily Theos_0950 f0dd210b2a5bd5869b839acd989ea26e 373 Gene3D G3DSA:3.40.640.10 40 271 1.2E-134 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0950 f0dd210b2a5bd5869b839acd989ea26e 373 Pfam PF00155 Aminotransferase class I and II 28 365 7.6E-57 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Theos_0950 f0dd210b2a5bd5869b839acd989ea26e 373 Gene3D G3DSA:3.90.1150.10 24 365 1.2E-134 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0950 f0dd210b2a5bd5869b839acd989ea26e 373 SUPERFAMILY SSF53383 5 367 1.46E-103 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_1553 162a722917b07ab8fa299c26dcd1bcf2 247 Pfam PF04474 Protein of unknown function (DUF554) 11 240 2.5E-71 T 14-10-2018 IPR007563 Protein of unknown function DUF554 Theos_1650 59e012bd5ce7f9fbc3b52c37bc5f8388 397 SUPERFAMILY SSF161098 137 384 9.42E-56 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1650 59e012bd5ce7f9fbc3b52c37bc5f8388 397 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 165 393 1.3E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1650 59e012bd5ce7f9fbc3b52c37bc5f8388 397 Gene3D G3DSA:1.10.3720.10 133 394 2.0E-70 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0174 77d9b0a6d08df4dcd9839810cf249ec8 220 Pfam PF01895 PhoU domain 17 103 1.4E-20 T 14-10-2018 IPR026022 PhoU domain Theos_0174 77d9b0a6d08df4dcd9839810cf249ec8 220 Pfam PF01895 PhoU domain 119 204 2.7E-19 T 14-10-2018 IPR026022 PhoU domain Theos_0174 77d9b0a6d08df4dcd9839810cf249ec8 220 Gene3D G3DSA:1.20.58.220 1 110 1.4E-33 T 14-10-2018 IPR038078 PhoU-like domain superfamily Theos_0174 77d9b0a6d08df4dcd9839810cf249ec8 220 PIRSF PIRSF003107 1 217 8.4E-67 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Theos_0174 77d9b0a6d08df4dcd9839810cf249ec8 220 Gene3D G3DSA:1.20.58.220 111 220 2.9E-35 T 14-10-2018 IPR038078 PhoU-like domain superfamily Theos_0174 77d9b0a6d08df4dcd9839810cf249ec8 220 SUPERFAMILY SSF109755 2 214 4.71E-68 T 14-10-2018 Theos_0174 77d9b0a6d08df4dcd9839810cf249ec8 220 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 212 3.6E-65 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Theos_2097 9afc800b2016dd104eef1ed574abfd7e 73 Gene3D G3DSA:3.30.920.30 4 72 1.7E-16 T 14-10-2018 IPR038570 HicA superfamily Theos_2097 9afc800b2016dd104eef1ed574abfd7e 73 SUPERFAMILY SSF54786 4 72 5.89E-16 T 14-10-2018 Theos_2097 9afc800b2016dd104eef1ed574abfd7e 73 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 8 63 6.6E-15 T 14-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Theos_0254 a41ec82f77471a15cb07a5726f3c5a85 101 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 99 8.5E-37 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0254 a41ec82f77471a15cb07a5726f3c5a85 101 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 9.2E-33 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0254 a41ec82f77471a15cb07a5726f3c5a85 101 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 101 25.133 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0254 a41ec82f77471a15cb07a5726f3c5a85 101 SUPERFAMILY SSF141091 1 99 8.5E-35 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_0230 167a86112d0ef8dbce67f19bebd6cfc5 151 Gene3D G3DSA:3.90.79.10 15 151 2.0E-30 T 14-10-2018 Theos_0230 167a86112d0ef8dbce67f19bebd6cfc5 151 Pfam PF00293 NUDIX domain 18 144 8.4E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Theos_0230 167a86112d0ef8dbce67f19bebd6cfc5 151 SUPERFAMILY SSF55811 13 150 1.03E-26 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Theos_0230 167a86112d0ef8dbce67f19bebd6cfc5 151 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Theos_1237 96b706a4894c1168b2acd9d416785a59 186 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 25 3.2E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1237 96b706a4894c1168b2acd9d416785a59 186 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 1.1E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1311 e998ea5c8ab659edc579a5ab53d0a13d 266 SUPERFAMILY SSF47413 17 81 2.58E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Theos_1311 e998ea5c8ab659edc579a5ab53d0a13d 266 Pfam PF13560 Helix-turn-helix domain 18 78 5.5E-8 T 14-10-2018 Theos_1311 e998ea5c8ab659edc579a5ab53d0a13d 266 SUPERFAMILY SSF51306 124 243 5.76E-15 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Theos_1311 e998ea5c8ab659edc579a5ab53d0a13d 266 Gene3D G3DSA:2.10.109.10 125 247 6.2E-10 T 14-10-2018 Theos_1311 e998ea5c8ab659edc579a5ab53d0a13d 266 Gene3D G3DSA:1.10.260.40 15 95 1.8E-8 T 14-10-2018 Theos_1311 e998ea5c8ab659edc579a5ab53d0a13d 266 Pfam PF00717 Peptidase S24-like 158 206 4.5E-7 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Theos_1311 e998ea5c8ab659edc579a5ab53d0a13d 266 SMART SM00530 22 80 8.3E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Theos_0968 536499109d4e820b1cb49fb59dc9f7d5 461 Pfam PF13556 PucR C-terminal helix-turn-helix domain 393 455 4.6E-15 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain Theos_0968 536499109d4e820b1cb49fb59dc9f7d5 461 Gene3D G3DSA:1.10.10.2840 336 459 9.7E-16 T 14-10-2018 Theos_1479 c2cce58b31f1c247bac7e0ba33d83042 223 Pfam PF03741 Integral membrane protein TerC family 11 181 8.2E-49 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 Theos_1479 c2cce58b31f1c247bac7e0ba33d83042 223 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 8 218 2.5E-70 T 14-10-2018 IPR022493 Integral membrane YkoY Theos_1608 1940474224f38e20a6c034b35f26ff9b 142 Gene3D G3DSA:2.40.50.140 24 132 1.9E-33 T 14-10-2018 Theos_1608 1940474224f38e20a6c034b35f26ff9b 142 Pfam PF03100 CcmE 2 125 4.6E-40 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 Theos_1608 1940474224f38e20a6c034b35f26ff9b 142 SUPERFAMILY SSF82093 24 126 1.29E-33 T 14-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 Theos_1608 1940474224f38e20a6c034b35f26ff9b 142 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 138 25.887 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 Theos_2333 0f47830768cbdda883a1addb39447383 234 SMART SM00382 27 214 2.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_2333 0f47830768cbdda883a1addb39447383 234 Gene3D G3DSA:3.40.50.300 1 234 2.1E-57 T 14-10-2018 Theos_2333 0f47830768cbdda883a1addb39447383 234 SUPERFAMILY SSF52540 3 231 9.35E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2333 0f47830768cbdda883a1addb39447383 234 Pfam PF00005 ABC transporter 20 162 2.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_2333 0f47830768cbdda883a1addb39447383 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_2186 b4a6f80aca54ea342dcfe485bef33690 131 Gene3D G3DSA:3.30.1490.190 74 130 3.9E-12 T 14-10-2018 Theos_2186 b4a6f80aca54ea342dcfe485bef33690 131 Pfam PF01475 Ferric uptake regulator family 5 93 7.1E-25 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Theos_2186 b4a6f80aca54ea342dcfe485bef33690 131 Gene3D G3DSA:1.10.10.10 2 72 1.8E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2186 b4a6f80aca54ea342dcfe485bef33690 131 SUPERFAMILY SSF46785 5 123 2.73E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1794 6961769e4910d2c2355974b2b2fd320c 235 SUPERFAMILY SSF53167 4 233 3.27E-78 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Theos_1794 6961769e4910d2c2355974b2b2fd320c 235 Gene3D G3DSA:3.40.50.1580 1 235 2.0E-78 T 14-10-2018 Theos_1794 6961769e4910d2c2355974b2b2fd320c 235 Pfam PF01048 Phosphorylase superfamily 16 230 1.7E-43 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Theos_2246 d15f8f0efcad86e30e388fab4fe6ce00 154 Gene3D G3DSA:3.50.70.20 17 154 4.4E-30 T 14-10-2018 IPR038142 Cytochrome P460 superfamily Theos_2246 d15f8f0efcad86e30e388fab4fe6ce00 154 Pfam PF16694 Cytochrome P460 25 150 4.1E-31 T 14-10-2018 IPR032033 Cytochrome P460 Theos_1606 af5e8e22cc1f2f342b546d81a1bfdbc9 177 Pfam PF00578 AhpC/TSA family 36 156 3.9E-18 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Theos_1606 af5e8e22cc1f2f342b546d81a1bfdbc9 177 SUPERFAMILY SSF52833 31 176 8.73E-39 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_1606 af5e8e22cc1f2f342b546d81a1bfdbc9 177 Gene3D G3DSA:3.40.30.10 19 177 3.4E-36 T 14-10-2018 Theos_2075 8658c5888ed587e651957cfbe4edd664 168 SUPERFAMILY SSF55729 9 148 5.93E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_2075 8658c5888ed587e651957cfbe4edd664 168 Gene3D G3DSA:3.40.630.30 2 160 1.6E-37 T 14-10-2018 Theos_2075 8658c5888ed587e651957cfbe4edd664 168 Pfam PF00583 Acetyltransferase (GNAT) family 59 143 7.2E-9 T 14-10-2018 IPR000182 GNAT domain Theos_1695 9cbbc2e75df7ba694e5291c267a680fd 108 Gene3D G3DSA:3.40.1350.10 4 69 1.4E-5 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 Theos_1695 9cbbc2e75df7ba694e5291c267a680fd 108 SUPERFAMILY SSF52980 11 63 7.24E-6 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_1319 84474a55017d1ea27d7b3081f89711be 105 Gene3D G3DSA:3.40.1350.10 3 69 9.4E-8 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 Theos_1319 84474a55017d1ea27d7b3081f89711be 105 SUPERFAMILY SSF52980 10 62 2.68E-5 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_1617 88e79e4115c07c4a4178bea3be4961a1 283 SUPERFAMILY SSF103247 166 273 1.44E-10 T 14-10-2018 IPR035923 TT1751-like domain superfamily Theos_1617 88e79e4115c07c4a4178bea3be4961a1 283 SUPERFAMILY SSF103247 20 132 1.7E-11 T 14-10-2018 IPR035923 TT1751-like domain superfamily Theos_1935 afd40e6edcfb8c2796df3ca4817c73f3 105 Gene3D G3DSA:2.20.28.30 60 93 1.0E-5 T 14-10-2018 Theos_1935 afd40e6edcfb8c2796df3ca4817c73f3 105 Gene3D G3DSA:2.20.28.160 6 55 2.1E-11 T 14-10-2018 Theos_1598 95c5362849029a51f021eef10f2e7a45 244 Pfam PF14332 Domain of unknown function (DUF4388) 2 100 5.3E-16 T 14-10-2018 IPR025497 Domain of unknown function DUF4388 Theos_2114 28cf5a20309559072ecd1e0b5d7468f2 312 SUPERFAMILY SSF55120 3 243 2.56E-63 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_2114 28cf5a20309559072ecd1e0b5d7468f2 312 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 241 7.1E-55 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_2114 28cf5a20309559072ecd1e0b5d7468f2 312 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 22 153 1.3E-39 T 14-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 Theos_2114 28cf5a20309559072ecd1e0b5d7468f2 312 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 308 14.655 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Theos_1287 fa349ae1a4593b7f3da0edd0bf21029d 329 Pfam PF03283 Pectinacetylesterase 26 206 4.7E-27 T 14-10-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 Theos_1287 fa349ae1a4593b7f3da0edd0bf21029d 329 Gene3D G3DSA:3.40.50.1820 37 303 2.1E-5 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1287 fa349ae1a4593b7f3da0edd0bf21029d 329 SUPERFAMILY SSF53474 23 297 6.52E-10 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_2265 45fe4bd7e1ba82d6c713e9de925f3f40 312 SUPERFAMILY SSF56349 51 294 6.18E-11 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Theos_2265 45fe4bd7e1ba82d6c713e9de925f3f40 312 Gene3D G3DSA:1.10.443.10 137 308 7.6E-6 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Theos_2057 db08af2e26298e8e5ad60cf262f5e9cc 172 Pfam PF11821 Protein of unknown function (DUF3341) 3 166 6.2E-49 T 14-10-2018 IPR021776 Protein of unknown function DUF3341 Theos_1538 96c65de78ab1efc8515c3d7fefa986ca 140 SUPERFAMILY SSF55718 2 134 4.0E-33 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily Theos_1538 96c65de78ab1efc8515c3d7fefa986ca 140 Gene3D G3DSA:3.30.1050.10 3 132 2.0E-41 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily Theos_1538 96c65de78ab1efc8515c3d7fefa986ca 140 Pfam PF02036 SCP-2 sterol transfer family 12 119 1.1E-10 T 14-10-2018 IPR003033 SCP2 sterol-binding domain Theos_0526 bdcd464bf1d60ede3ad676908308709a 325 Gene3D G3DSA:3.40.190.10 112 257 2.4E-90 T 14-10-2018 Theos_0526 bdcd464bf1d60ede3ad676908308709a 325 Gene3D G3DSA:3.40.190.10 24 322 2.4E-90 T 14-10-2018 Theos_0526 bdcd464bf1d60ede3ad676908308709a 325 Pfam PF16868 NMT1-like family 24 322 1.3E-68 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Theos_0526 bdcd464bf1d60ede3ad676908308709a 325 SUPERFAMILY SSF53850 21 324 7.7E-57 T 14-10-2018 Theos_0526 bdcd464bf1d60ede3ad676908308709a 325 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 7 322 1.8E-77 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Theos_2091 1d583520ee626e61843947b1c9073928 222 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 79 94 - T 14-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Theos_2091 1d583520ee626e61843947b1c9073928 222 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 39 210 4.4E-45 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Theos_2091 1d583520ee626e61843947b1c9073928 222 PIRSF PIRSF016262 5 221 2.2E-57 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Theos_2091 1d583520ee626e61843947b1c9073928 222 Hamap MF_00013 Octanoyltransferase [lipB]. 6 212 33.788 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Theos_2091 1d583520ee626e61843947b1c9073928 222 SUPERFAMILY SSF55681 5 211 4.39E-62 T 14-10-2018 Theos_2091 1d583520ee626e61843947b1c9073928 222 Gene3D G3DSA:3.30.930.10 5 210 2.2E-79 T 14-10-2018 Theos_2091 1d583520ee626e61843947b1c9073928 222 Pfam PF03099 Biotin/lipoate A/B protein ligase family 69 164 2.6E-6 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Theos_2091 1d583520ee626e61843947b1c9073928 222 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 83 127 6.0E-17 T 14-10-2018 Theos_0636 0acc441ceff87cd9950e9cf61195af5d 342 Pfam PF08486 Stage II sporulation protein 87 174 1.5E-25 T 14-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal Theos_0636 0acc441ceff87cd9950e9cf61195af5d 342 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 91 333 4.3E-70 T 14-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 Theos_2339 bd56263836086cb4842e881206f51e7f 296 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 33 1.0E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_2339 bd56263836086cb4842e881206f51e7f 296 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 32 3.8E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_2339 bd56263836086cb4842e881206f51e7f 296 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_1774 154ec89aae68cf117e8fab7d205e5548 48 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 14-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Theos_1774 154ec89aae68cf117e8fab7d205e5548 48 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.783 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1774 154ec89aae68cf117e8fab7d205e5548 48 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 39 8.0E-14 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1774 154ec89aae68cf117e8fab7d205e5548 48 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 43 3.8E-21 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1774 154ec89aae68cf117e8fab7d205e5548 48 Pfam PF00468 Ribosomal protein L34 1 43 1.8E-23 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1429 dbc5d220f1910e115db363d0d763ebd7 265 Pfam PF01497 Periplasmic binding protein 20 209 5.1E-20 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain Theos_1429 dbc5d220f1910e115db363d0d763ebd7 265 Gene3D G3DSA:3.40.50.1980 12 134 1.2E-26 T 14-10-2018 Theos_1429 dbc5d220f1910e115db363d0d763ebd7 265 Gene3D G3DSA:3.40.50.1980 135 260 1.1E-9 T 14-10-2018 Theos_1429 dbc5d220f1910e115db363d0d763ebd7 265 SUPERFAMILY SSF53807 18 257 8.5E-40 T 14-10-2018 Theos_1112 a8869d28c123faeb4e7e57361e5c7fba 53 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 2.9E-21 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Theos_1112 a8869d28c123faeb4e7e57361e5c7fba 53 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 51 18.722 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Theos_1112 a8869d28c123faeb4e7e57361e5c7fba 53 Pfam PF02416 mttA/Hcf106 family 3 52 3.5E-19 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 Theos_2299 8ffc38aef17db82b132c3a7fce3cf0c5 254 Pfam PF02602 Uroporphyrinogen-III synthase HemD 13 242 1.3E-33 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2299 8ffc38aef17db82b132c3a7fce3cf0c5 254 Gene3D G3DSA:3.40.50.10090 31 159 7.7E-74 T 14-10-2018 Theos_2299 8ffc38aef17db82b132c3a7fce3cf0c5 254 SUPERFAMILY SSF69618 7 245 1.31E-45 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Theos_2299 8ffc38aef17db82b132c3a7fce3cf0c5 254 Gene3D G3DSA:3.40.50.10090 7 240 7.7E-74 T 14-10-2018 Theos_0646 d4c320d266faa7ad614c159ec2964976 356 Pfam PF07690 Major Facilitator Superfamily 33 308 2.0E-8 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_0646 d4c320d266faa7ad614c159ec2964976 356 Gene3D G3DSA:1.20.1250.20 12 351 1.8E-15 T 14-10-2018 Theos_0646 d4c320d266faa7ad614c159ec2964976 356 SUPERFAMILY SSF103473 34 351 1.96E-19 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_0958 5473875366160b35099f9e25c3c5a554 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 277 2.3E-90 T 14-10-2018 IPR003797 DegV Theos_0958 5473875366160b35099f9e25c3c5a554 280 Gene3D G3DSA:3.40.50.10170 1 150 4.1E-58 T 14-10-2018 Theos_0958 5473875366160b35099f9e25c3c5a554 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 278 5.2E-84 T 14-10-2018 IPR003797 DegV Theos_0958 5473875366160b35099f9e25c3c5a554 280 SUPERFAMILY SSF82549 1 278 6.8E-83 T 14-10-2018 Theos_0958 5473875366160b35099f9e25c3c5a554 280 Gene3D G3DSA:3.30.1180.10 151 280 3.0E-44 T 14-10-2018 Theos_1436 540be34f67919740b13c6ee48f6f642c 225 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 12 215 6.1E-66 T 14-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 Theos_1436 540be34f67919740b13c6ee48f6f642c 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 207 2.2E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1436 540be34f67919740b13c6ee48f6f642c 225 SUPERFAMILY SSF161098 3 211 3.27E-49 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1436 540be34f67919740b13c6ee48f6f642c 225 Gene3D G3DSA:1.10.3720.10 1 218 8.0E-57 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1497 9e480fdd9c2e9472e3f905d9e43fce17 34 Pfam PF08113 Cytochrome c oxidase subunit IIa family 2 34 9.5E-19 T 14-10-2018 IPR012538 Cytochrome c oxidase polypeptide 2A KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Theos_1497 9e480fdd9c2e9472e3f905d9e43fce17 34 SUPERFAMILY SSF81473 2 34 1.27E-14 T 14-10-2018 IPR036246 Cytochrome c oxidase polypeptide 2A, ba3 type KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Theos_1591 0dd58129b0ce887f1c5a4e820368fc19 77 SUPERFAMILY SSF52833 3 74 6.46E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_1591 0dd58129b0ce887f1c5a4e820368fc19 77 Gene3D G3DSA:3.40.30.10 1 71 3.6E-15 T 14-10-2018 Theos_1591 0dd58129b0ce887f1c5a4e820368fc19 77 Pfam PF05768 Glutaredoxin-like domain (DUF836) 3 54 7.7E-10 T 14-10-2018 IPR008554 Glutaredoxin-like Theos_2184 26f05ed04a1c72c85977450aaa48947f 385 Gene3D G3DSA:3.40.640.10 58 276 3.3E-119 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_2184 26f05ed04a1c72c85977450aaa48947f 385 SUPERFAMILY SSF53383 7 375 8.47E-88 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_2184 26f05ed04a1c72c85977450aaa48947f 385 Gene3D G3DSA:3.90.1150.10 27 370 3.3E-119 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_2184 26f05ed04a1c72c85977450aaa48947f 385 Pfam PF00155 Aminotransferase class I and II 27 371 9.3E-36 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Theos_2250 9b879e1b6dfccf801933642fae1c365c 167 Gene3D G3DSA:2.60.120.10 10 164 5.5E-37 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_2250 9b879e1b6dfccf801933642fae1c365c 167 SUPERFAMILY SSF51182 23 146 4.22E-21 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Theos_2250 9b879e1b6dfccf801933642fae1c365c 167 Pfam PF07883 Cupin domain 51 112 4.4E-16 T 14-10-2018 IPR013096 Cupin 2, conserved barrel Theos_0561 d22b05b134625f1e04002f6cb36c8a6f 436 Gene3D G3DSA:3.30.2290.10 1 208 1.2E-30 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Theos_0561 d22b05b134625f1e04002f6cb36c8a6f 436 Pfam PF01523 Putative modulator of DNA gyrase 20 305 8.2E-58 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Theos_0561 d22b05b134625f1e04002f6cb36c8a6f 436 SUPERFAMILY SSF111283 3 435 3.4E-98 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Theos_0965 14dbf2c0e4727f611e0bed586cb2d67a 398 Pfam PF12704 MacB-like periplasmic core domain 17 193 2.2E-9 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Theos_0965 14dbf2c0e4727f611e0bed586cb2d67a 398 Pfam PF02687 FtsX-like permease family 284 390 1.5E-10 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Theos_0811 dde3a1d47ddfd25a240e67c692d62cbe 224 SMART SM00849 8 187 6.4E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0811 dde3a1d47ddfd25a240e67c692d62cbe 224 Gene3D G3DSA:3.60.15.10 2 223 1.7E-70 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_0811 dde3a1d47ddfd25a240e67c692d62cbe 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 223 37.103 T 14-10-2018 IPR022877 Protein of unknown funcion UPF0173 Theos_0811 dde3a1d47ddfd25a240e67c692d62cbe 224 Pfam PF13483 Beta-lactamase superfamily domain 3 187 7.4E-23 T 14-10-2018 Theos_0811 dde3a1d47ddfd25a240e67c692d62cbe 224 SUPERFAMILY SSF56281 2 211 2.23E-38 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_1549 921b561c4a6b3ef1a72b7aa11dc1c985 223 Pfam PF00535 Glycosyl transferase family 2 1 119 8.9E-30 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Theos_1549 921b561c4a6b3ef1a72b7aa11dc1c985 223 Gene3D G3DSA:3.90.550.10 1 191 2.6E-41 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1549 921b561c4a6b3ef1a72b7aa11dc1c985 223 SUPERFAMILY SSF53448 1 208 6.65E-48 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_2411 b8fc56a1bdd49b6ef1190b7723670bc4 408 SUPERFAMILY SSF103473 6 405 1.44E-67 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_2411 b8fc56a1bdd49b6ef1190b7723670bc4 408 Gene3D G3DSA:1.20.1250.20 5 403 4.4E-53 T 14-10-2018 Theos_2411 b8fc56a1bdd49b6ef1190b7723670bc4 408 Pfam PF07690 Major Facilitator Superfamily 16 235 4.3E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Theos_2525 fbf118fc15891b1c920fb0fbf5e2dbce 120 Pfam PF01927 Mut7-C RNAse domain 6 91 6.5E-7 T 14-10-2018 IPR002782 Mut7-C RNAse domain Theos_0212 4a4195e049fc3cf44e01a113c1caf0f4 237 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 6 231 1.3E-66 T 14-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 Theos_0212 4a4195e049fc3cf44e01a113c1caf0f4 237 Gene3D G3DSA:3.40.1700.10 93 235 6.7E-47 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily Theos_0212 4a4195e049fc3cf44e01a113c1caf0f4 237 SUPERFAMILY SSF143597 33 219 4.45E-55 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily Theos_0212 4a4195e049fc3cf44e01a113c1caf0f4 237 Hamap MF_01499 Diadenylate cyclase [dacA]. 1 236 31.288 T 14-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 Theos_0212 4a4195e049fc3cf44e01a113c1caf0f4 237 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 104 217 1.3E-35 T 14-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal Theos_0212 4a4195e049fc3cf44e01a113c1caf0f4 237 PIRSF PIRSF004793 2 237 1.2E-80 T 14-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 Theos_1849 346e16de241981416ff7c163a88ef1c8 224 Pfam PF00005 ABC transporter 22 149 1.0E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1849 346e16de241981416ff7c163a88ef1c8 224 SMART SM00382 28 197 7.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1849 346e16de241981416ff7c163a88ef1c8 224 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1849 346e16de241981416ff7c163a88ef1c8 224 SUPERFAMILY SSF52540 3 211 3.26E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1849 346e16de241981416ff7c163a88ef1c8 224 Gene3D G3DSA:3.40.50.300 8 223 8.7E-59 T 14-10-2018 Theos_0366 9af2ac8dfc4a2d97b7d12ddf9dd3384c 200 SUPERFAMILY SSF51366 1 196 2.04E-56 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Theos_0366 9af2ac8dfc4a2d97b7d12ddf9dd3384c 200 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 193 2.8E-38 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Theos_0366 9af2ac8dfc4a2d97b7d12ddf9dd3384c 200 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 199 35.164 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Theos_0366 9af2ac8dfc4a2d97b7d12ddf9dd3384c 200 Gene3D G3DSA:3.20.20.70 1 199 1.4E-77 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_2142 b6d2307aae139a4b2b946b01c4225169 278 Gene3D G3DSA:3.20.20.20 1 277 1.9E-112 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_2142 b6d2307aae139a4b2b946b01c4225169 278 Pfam PF00809 Pterin binding enzyme 17 255 3.8E-81 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_2142 b6d2307aae139a4b2b946b01c4225169 278 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 269 1.7E-94 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 Theos_2142 b6d2307aae139a4b2b946b01c4225169 278 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_2142 b6d2307aae139a4b2b946b01c4225169 278 SUPERFAMILY SSF51717 7 272 8.77E-97 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_2142 b6d2307aae139a4b2b946b01c4225169 278 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Theos_1360 6af86a40846c127ae694d3e1a89328fa 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 4.8E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_1360 6af86a40846c127ae694d3e1a89328fa 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 4.8E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_1360 6af86a40846c127ae694d3e1a89328fa 189 SUPERFAMILY SSF48498 73 184 6.79E-27 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Theos_1360 6af86a40846c127ae694d3e1a89328fa 189 SUPERFAMILY SSF46689 2 64 1.74E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_1360 6af86a40846c127ae694d3e1a89328fa 189 Gene3D G3DSA:1.10.357.10 45 185 3.3E-40 T 14-10-2018 Theos_1360 6af86a40846c127ae694d3e1a89328fa 189 Gene3D G3DSA:1.10.10.60 1 43 8.7E-23 T 14-10-2018 Theos_1360 6af86a40846c127ae694d3e1a89328fa 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 5.7E-20 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Theos_1360 6af86a40846c127ae694d3e1a89328fa 189 ProSitePatterns PS01081 TetR-type HTH domain signature. 19 50 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Theos_0385 7c5bdd0384ed4c171f8d3022e74f2879 194 SUPERFAMILY SSF49482 14 174 2.09E-42 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Theos_0385 7c5bdd0384ed4c171f8d3022e74f2879 194 Pfam PF00775 Dioxygenase 33 129 8.1E-11 T 14-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 Theos_0385 7c5bdd0384ed4c171f8d3022e74f2879 194 Gene3D G3DSA:2.60.130.10 22 193 2.1E-38 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Theos_1994 acca589e36ab3d39a86c67088c5ad64e 141 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 18 103 3.0E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1994 acca589e36ab3d39a86c67088c5ad64e 141 SUPERFAMILY SSF46626 19 125 1.43E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1994 acca589e36ab3d39a86c67088c5ad64e 141 Gene3D G3DSA:1.10.760.10 17 140 2.1E-41 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_0418 7749c9400d1507d8367cf223dc543497 381 Pfam PF04294 VanW like protein 152 280 9.3E-42 T 14-10-2018 IPR007391 Vancomycin resistance VanW Theos_0856 650930b07ea208c8c9f4f293bca6246b 155 Pfam PF00578 AhpC/TSA family 3 131 2.0E-41 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Theos_0856 650930b07ea208c8c9f4f293bca6246b 155 SUPERFAMILY SSF52833 2 152 3.14E-54 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Theos_0856 650930b07ea208c8c9f4f293bca6246b 155 Gene3D G3DSA:3.40.30.10 1 151 2.6E-53 T 14-10-2018 Theos_0856 650930b07ea208c8c9f4f293bca6246b 155 PIRSF PIRSF000239 1 155 2.1E-28 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Theos_1243 fceea0348311a394f87366709023f764 144 Gene3D G3DSA:1.20.120.20 2 138 8.1E-9 T 14-10-2018 Theos_1243 fceea0348311a394f87366709023f764 144 Pfam PF05823 Nematode fatty acid retinoid binding protein (Gp-FAR-1) 33 131 3.5E-8 T 14-10-2018 IPR008632 Nematode fatty acid retinoid binding GO:0008289 Theos_1243 fceea0348311a394f87366709023f764 144 SUPERFAMILY SSF58113 6 125 1.83E-7 T 14-10-2018 Theos_1104 916b6d78f4f0fcd64a231e411f321f71 407 Gene3D G3DSA:3.40.50.410 216 391 6.1E-16 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_1104 916b6d78f4f0fcd64a231e411f321f71 407 Pfam PF13519 von Willebrand factor type A domain 219 317 3.9E-7 T 14-10-2018 IPR002035 von Willebrand factor, type A Theos_1104 916b6d78f4f0fcd64a231e411f321f71 407 SUPERFAMILY SSF53300 219 386 1.75E-15 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Theos_2079 cd73359b77d614f29e3387ecce43e94f 620 Gene3D G3DSA:3.40.50.300 121 252 1.3E-11 T 14-10-2018 Theos_2079 cd73359b77d614f29e3387ecce43e94f 620 SUPERFAMILY SSF52540 99 243 8.4E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2079 cd73359b77d614f29e3387ecce43e94f 620 Pfam PF07728 AAA domain (dynein-related subfamily) 125 216 7.1E-6 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Theos_2079 cd73359b77d614f29e3387ecce43e94f 620 Gene3D G3DSA:1.10.10.10 1 108 1.0E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2079 cd73359b77d614f29e3387ecce43e94f 620 SUPERFAMILY SSF46785 2 101 1.66E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_1636 5deacf99eed2d7936fe16b3899960425 147 Gene3D G3DSA:3.40.50.1010 5 137 1.7E-16 T 14-10-2018 Theos_1636 5deacf99eed2d7936fe16b3899960425 147 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 141 9.524 T 14-10-2018 IPR022907 VapC family GO:0004540 Theos_1636 5deacf99eed2d7936fe16b3899960425 147 SUPERFAMILY SSF88723 5 114 4.58E-15 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_1636 5deacf99eed2d7936fe16b3899960425 147 Pfam PF01850 PIN domain 5 115 1.8E-12 T 14-10-2018 IPR002716 PIN domain Theos_0314 abbe21df185b73aef22d7b0605b5dbfb 316 SUPERFAMILY SSF48576 6 313 2.88E-79 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Theos_0314 abbe21df185b73aef22d7b0605b5dbfb 316 Pfam PF00348 Polyprenyl synthetase 34 265 2.3E-64 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 Theos_0314 abbe21df185b73aef22d7b0605b5dbfb 316 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 200 212 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site Theos_0314 abbe21df185b73aef22d7b0605b5dbfb 316 Gene3D G3DSA:1.10.600.10 7 314 8.0E-89 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Theos_0314 abbe21df185b73aef22d7b0605b5dbfb 316 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 92 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site Theos_2317 ea629c3b90e597245e3fb02b20087621 231 Gene3D G3DSA:3.40.50.10230 15 231 1.6E-87 T 14-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 Theos_2317 ea629c3b90e597245e3fb02b20087621 231 SUPERFAMILY SSF63965 21 220 7.98E-68 T 14-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 Theos_2317 ea629c3b90e597245e3fb02b20087621 231 Pfam PF02570 Precorrin-8X methylmutase 22 216 2.6E-72 T 14-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 Theos_1250 14e5b2f150fa1c2d48cd0c3d67edd690 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 2 197 35.999 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 Theos_1250 14e5b2f150fa1c2d48cd0c3d67edd690 201 SUPERFAMILY SSF52016 3 191 2.55E-45 T 14-10-2018 Theos_1250 14e5b2f150fa1c2d48cd0c3d67edd690 201 Gene3D G3DSA:3.20.19.10 1 178 1.3E-55 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Theos_1250 14e5b2f150fa1c2d48cd0c3d67edd690 201 Pfam PF00694 Aconitase C-terminal domain 3 122 2.9E-20 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Theos_1250 14e5b2f150fa1c2d48cd0c3d67edd690 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 3 183 7.5E-42 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 Theos_0964 bddddbaa110c68d9cb2d4f0ae1d2cf06 229 Pfam PF17131 Outer membrane lipoprotein-sorting protein 60 227 3.3E-31 T 14-10-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein Theos_0964 bddddbaa110c68d9cb2d4f0ae1d2cf06 229 Gene3D G3DSA:2.50.20.10 14 227 1.5E-32 T 14-10-2018 Theos_0579 b1842581f3498f8a076f197119d32acb 270 SUPERFAMILY SSF53850 4 258 1.6E-69 T 14-10-2018 Theos_0579 b1842581f3498f8a076f197119d32acb 270 Hamap MF_00995 Chorismate dehydratase [mqnA]. 4 265 28.46 T 14-10-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 Theos_0579 b1842581f3498f8a076f197119d32acb 270 Pfam PF02621 Menaquinone biosynthesis 3 258 1.1E-61 T 14-10-2018 IPR003773 Menaquinone biosynthesis enzyme Theos_0579 b1842581f3498f8a076f197119d32acb 270 Gene3D G3DSA:3.40.190.10 72 194 1.5E-70 T 14-10-2018 Theos_0579 b1842581f3498f8a076f197119d32acb 270 Gene3D G3DSA:3.40.190.10 8 255 1.5E-70 T 14-10-2018 Theos_1282 d3737da333eb6cb1ddf258db1ae6525e 284 SUPERFAMILY SSF103481 181 283 3.14E-18 T 14-10-2018 Theos_1282 d3737da333eb6cb1ddf258db1ae6525e 284 SUPERFAMILY SSF103481 39 139 1.16E-18 T 14-10-2018 Theos_1282 d3737da333eb6cb1ddf258db1ae6525e 284 Pfam PF00892 EamA-like transporter family 5 136 2.0E-24 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_1282 d3737da333eb6cb1ddf258db1ae6525e 284 Pfam PF00892 EamA-like transporter family 147 281 5.4E-28 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_0644 836fd9edb7fa441806930e0894cc0c4f 557 Pfam PF01039 Carboxyl transferase domain 52 547 4.4E-138 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 Theos_0644 836fd9edb7fa441806930e0894cc0c4f 557 Gene3D G3DSA:3.90.226.10 281 552 9.1E-93 T 14-10-2018 Theos_0644 836fd9edb7fa441806930e0894cc0c4f 557 SUPERFAMILY SSF52096 284 550 5.6E-79 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_0644 836fd9edb7fa441806930e0894cc0c4f 557 Gene3D G3DSA:3.90.226.10 5 273 2.6E-85 T 14-10-2018 Theos_0644 836fd9edb7fa441806930e0894cc0c4f 557 SUPERFAMILY SSF52096 30 276 1.85E-64 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_2302 c1ad43f361c6ab5b1e9e8bdd0a834664 244 Pfam PF01925 Sulfite exporter TauE/SafE 3 235 2.7E-30 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Theos_1577 3c28ba1f24672c6d356778d4a3f880e8 336 Pfam PF03739 Predicted permease YjgP/YjgQ family 4 334 8.5E-49 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Theos_1845 78eb8409e52b9f9f06a4dc2daee2905c 326 Pfam PF06089 L-asparaginase II 6 318 8.3E-103 T 14-10-2018 IPR010349 L-asparaginase II Theos_0828 d89ab36101df0254d370d9953914a908 380 Pfam PF03787 RAMP superfamily 10 221 3.0E-9 T 14-10-2018 IPR005537 CRISPR type III-associated RAMP protein Theos_0828 d89ab36101df0254d370d9953914a908 380 TIGRFAM TIGR01899 cas_TM1807_csm5: CRISPR type III-A/MTUBE-associated RAMP protein Csm5 10 338 3.9E-18 T 14-10-2018 IPR010173 CRISPR-associated protein, TM1807 Theos_0909 0167587d938c7a4a73b01b41d7533bad 82 Pfam PF13453 Transcription factor zinc-finger 6 44 1.1E-18 T 14-10-2018 IPR027392 Transcription factor zinc-finger Theos_2089 6d1c1ca872fbb2a7ffc1663a8c54f188 395 Pfam PF00589 Phage integrase family 189 372 5.4E-33 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Theos_2089 6d1c1ca872fbb2a7ffc1663a8c54f188 395 Gene3D G3DSA:1.10.150.130 66 182 2.6E-24 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Theos_2089 6d1c1ca872fbb2a7ffc1663a8c54f188 395 SUPERFAMILY SSF56349 70 376 1.03E-67 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Theos_2089 6d1c1ca872fbb2a7ffc1663a8c54f188 395 Gene3D G3DSA:1.10.443.10 188 384 1.2E-54 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Theos_0429 8ca9bb634825eb7cb27d075958498c1d 119 Pfam PF09685 Domain of unknown function (DUF4870) 10 119 7.1E-22 T 14-10-2018 IPR019109 Protein of unknown function DUF4870 Theos_0578 93b7711cf4ad82bdaaa2a89291799c8e 178 SMART SM00867 2 170 1.7E-62 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Theos_0578 93b7711cf4ad82bdaaa2a89291799c8e 178 SUPERFAMILY SSF101874 2 172 1.96E-54 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Theos_0578 93b7711cf4ad82bdaaa2a89291799c8e 178 Pfam PF04264 YceI-like domain 3 169 2.8E-38 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Theos_0578 93b7711cf4ad82bdaaa2a89291799c8e 178 Gene3D G3DSA:2.40.128.110 1 177 6.8E-53 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Theos_0162 4ba6c20952cb6a1e68de56b34f9d3ba6 152 Gene3D G3DSA:1.10.3820.10 5 152 8.1E-40 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily Theos_0162 4ba6c20952cb6a1e68de56b34f9d3ba6 152 SUPERFAMILY SSF48695 13 149 1.3E-21 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily Theos_0162 4ba6c20952cb6a1e68de56b34f9d3ba6 152 TIGRFAM TIGR03153 cytochr_NrfH: cytochrome c nitrite reductase, small subunit 13 148 8.6E-49 T 14-10-2018 IPR017571 Cytochrome c nitrite reductase, small subunit GO:0016021|GO:0022900 Theos_0162 4ba6c20952cb6a1e68de56b34f9d3ba6 152 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 13 150 9.1E-11 T 14-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal Theos_0507 90b261d24dbbd31061d8ef8fcb4e3fc3 340 Gene3D G3DSA:1.10.3720.10 129 335 5.7E-26 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0507 90b261d24dbbd31061d8ef8fcb4e3fc3 340 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 51 1.4E-10 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Theos_0507 90b261d24dbbd31061d8ef8fcb4e3fc3 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 156 339 2.2E-32 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0507 90b261d24dbbd31061d8ef8fcb4e3fc3 340 SUPERFAMILY SSF161098 133 320 5.76E-33 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1033 12deb6f74dcf9cd570987b659d7d37f2 270 SUPERFAMILY SSF140683 8 77 9.68E-13 T 14-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily Theos_1033 12deb6f74dcf9cd570987b659d7d37f2 270 Gene3D G3DSA:1.10.3910.10 5 77 1.9E-9 T 14-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily Theos_1033 12deb6f74dcf9cd570987b659d7d37f2 270 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 108 176 2.4E-14 T 14-10-2018 IPR018720 Domain of unknown function DUF2249 Theos_1033 12deb6f74dcf9cd570987b659d7d37f2 270 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 210 269 1.2E-11 T 14-10-2018 IPR018720 Domain of unknown function DUF2249 Theos_1033 12deb6f74dcf9cd570987b659d7d37f2 270 Pfam PF08984 Domain of unknown function (DUF1858) 10 69 1.4E-12 T 14-10-2018 IPR015077 Domain of unknown function DUF1858 Theos_2502 e456cbd072017b0faced6b336e527b40 98 Pfam PF04434 SWIM zinc finger 47 78 1.9E-6 T 14-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 Theos_1677 890b141762a43114cec9c1663eacbc0f 310 Gene3D G3DSA:3.30.479.30 72 218 4.0E-6 T 14-10-2018 Theos_1677 890b141762a43114cec9c1663eacbc0f 310 SMART SM00244 41 216 9.6E-13 T 14-10-2018 IPR001107 Band 7 domain Theos_1677 890b141762a43114cec9c1663eacbc0f 310 SUPERFAMILY SSF117892 74 221 5.62E-17 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily Theos_1677 890b141762a43114cec9c1663eacbc0f 310 Pfam PF01145 SPFH domain / Band 7 family 46 231 1.0E-28 T 14-10-2018 IPR001107 Band 7 domain Theos_0621 73a241738852813b10060d04fc853cc6 432 Gene3D G3DSA:3.90.1150.10 13 426 2.6E-152 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_0621 73a241738852813b10060d04fc853cc6 432 SUPERFAMILY SSF53383 28 430 1.48E-128 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0621 73a241738852813b10060d04fc853cc6 432 Gene3D G3DSA:3.40.640.10 69 331 2.6E-152 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0621 73a241738852813b10060d04fc853cc6 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0621 73a241738852813b10060d04fc853cc6 432 PIRSF PIRSF000521 131 432 1.6E-42 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0621 73a241738852813b10060d04fc853cc6 432 PIRSF PIRSF000521 1 136 2.2E-8 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_0621 73a241738852813b10060d04fc853cc6 432 Pfam PF00202 Aminotransferase class-III 32 428 1.1E-114 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Theos_1047 aed89c9cffda777de0ffb8ac2599dbad 75 SUPERFAMILY SSF46785 8 50 5.55E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0917 a30ac2a5dd4004b3ffd81e6f2f970d27 202 Pfam PF02632 BioY family 48 197 9.1E-42 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 Theos_0917 a30ac2a5dd4004b3ffd81e6f2f970d27 202 Gene3D G3DSA:1.10.1760.20 19 199 7.9E-51 T 14-10-2018 Theos_0917 a30ac2a5dd4004b3ffd81e6f2f970d27 202 PIRSF PIRSF016661 11 202 6.0E-43 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 Theos_1682 d7934cd60b880a0cdf8908a7bc888342 599 Pfam PF00326 Prolyl oligopeptidase family 393 598 4.0E-47 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Theos_1682 d7934cd60b880a0cdf8908a7bc888342 599 SUPERFAMILY SSF82171 66 314 1.22E-11 T 14-10-2018 Theos_1682 d7934cd60b880a0cdf8908a7bc888342 599 Gene3D G3DSA:3.40.50.1820 342 599 4.2E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_1682 d7934cd60b880a0cdf8908a7bc888342 599 SUPERFAMILY SSF53474 351 599 4.75E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Theos_0013 799bef342b312e6e8258b90496a3d8af 93 Gene3D G3DSA:1.20.58.1000 1 93 4.5E-25 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily Theos_0013 799bef342b312e6e8258b90496a3d8af 93 Pfam PF02583 Metal-sensitive transcriptional repressor 13 91 3.4E-23 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 Theos_2044 3495ac80573c3f809f821e4e08113290 384 Pfam PF12679 ABC-2 family transporter protein 7 379 7.0E-21 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 Theos_2008 ffac3b3ec4707e3daa25f5fc9743b795 214 SUPERFAMILY SSF53254 15 207 1.07E-34 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_2008 ffac3b3ec4707e3daa25f5fc9743b795 214 Gene3D G3DSA:3.40.50.1240 15 210 6.8E-32 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Theos_2008 ffac3b3ec4707e3daa25f5fc9743b795 214 PIRSF PIRSF000709 85 158 0.0011 T 14-10-2018 Theos_2008 ffac3b3ec4707e3daa25f5fc9743b795 214 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 17 207 7.4E-37 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Theos_1780 9bc111d54cc1a3f47795fbc344504859 469 Pfam PF11283 Protein of unknown function (DUF3084) 4 78 1.4E-24 T 14-10-2018 IPR021435 Protein of unknown function DUF3084 Theos_2352 8303aa8e96c48cae8ed4454479177c47 112 SUPERFAMILY SSF46785 9 108 1.15E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2352 8303aa8e96c48cae8ed4454479177c47 112 Pfam PF12840 Helix-turn-helix domain 21 89 7.2E-15 T 14-10-2018 Theos_2352 8303aa8e96c48cae8ed4454479177c47 112 Gene3D G3DSA:1.10.10.10 7 110 2.3E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_2352 8303aa8e96c48cae8ed4454479177c47 112 SMART SM00418 21 108 8.1E-22 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Theos_2352 8303aa8e96c48cae8ed4454479177c47 112 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 54 72 - T 14-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 Theos_1408 a6f66526b238a99918b230e6a2362836 327 Pfam PF02562 PhoH-like protein 118 321 1.1E-98 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 Theos_1408 a6f66526b238a99918b230e6a2362836 327 SUPERFAMILY SSF52540 117 296 1.99E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1408 a6f66526b238a99918b230e6a2362836 327 Gene3D G3DSA:3.40.50.300 116 321 1.2E-77 T 14-10-2018 Theos_1776 856ded45c0bb39cb706b333e13352627 82 Pfam PF01809 Haemolytic domain 4 68 4.3E-29 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Theos_1776 856ded45c0bb39cb706b333e13352627 82 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.543 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Theos_1776 856ded45c0bb39cb706b333e13352627 82 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 70 5.1E-29 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Theos_1776 856ded45c0bb39cb706b333e13352627 82 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 66 1.0E-21 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Theos_1776 856ded45c0bb39cb706b333e13352627 82 SMART SM01234 1 68 1.6E-41 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Theos_1359 b0bc6d3a9be6dd08049536dc9ebbf834 554 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 40 472 2.2E-78 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Theos_1359 b0bc6d3a9be6dd08049536dc9ebbf834 554 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 13 545 2.9E-138 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ Theos_2335 2d8b1f3bc577ae56bd7c31e928693d50 547 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 265 344 5.4E-8 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal Theos_0072 c04d94b27953858c80c6e57c4dfe7b16 223 Pfam PF03749 Sugar fermentation stimulation protein 15 210 1.7E-47 T 14-10-2018 IPR005224 Sugar fermentation stimulation protein Theos_0072 c04d94b27953858c80c6e57c4dfe7b16 223 Gene3D G3DSA:3.40.1350.60 75 219 1.1E-33 T 14-10-2018 Theos_0072 c04d94b27953858c80c6e57c4dfe7b16 223 Gene3D G3DSA:2.40.50.580 1 72 2.6E-14 T 14-10-2018 Theos_2288 1b197aee0198d5bfcd96bcc30e3e75d8 436 SUPERFAMILY SSF53850 23 400 6.42E-67 T 14-10-2018 Theos_2288 1b197aee0198d5bfcd96bcc30e3e75d8 436 Gene3D G3DSA:3.40.190.10 139 402 3.4E-75 T 14-10-2018 Theos_2288 1b197aee0198d5bfcd96bcc30e3e75d8 436 Gene3D G3DSA:3.40.190.10 40 387 3.4E-75 T 14-10-2018 Theos_2288 1b197aee0198d5bfcd96bcc30e3e75d8 436 Pfam PF13416 Bacterial extracellular solute-binding protein 41 373 5.4E-36 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Theos_1324 2501d1f4f02831609ec99d8c6d6b5029 160 Pfam PF01850 PIN domain 3 141 2.0E-6 T 14-10-2018 IPR002716 PIN domain Theos_1324 2501d1f4f02831609ec99d8c6d6b5029 160 SUPERFAMILY SSF88723 3 148 1.01E-9 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_1324 2501d1f4f02831609ec99d8c6d6b5029 160 Gene3D G3DSA:3.40.50.1010 2 147 1.1E-10 T 14-10-2018 Theos_0191 60827cde248a7273a140d81912aaa88c 493 SUPERFAMILY SSF161098 254 487 3.27E-35 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0191 60827cde248a7273a140d81912aaa88c 493 Gene3D G3DSA:1.10.3720.10 2 241 9.1E-39 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0191 60827cde248a7273a140d81912aaa88c 493 Gene3D G3DSA:1.10.3720.10 255 492 5.1E-32 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0191 60827cde248a7273a140d81912aaa88c 493 SUPERFAMILY SSF161098 3 239 2.09E-32 T 14-10-2018 IPR035906 MetI-like superfamily Theos_0191 60827cde248a7273a140d81912aaa88c 493 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 60 227 2.5E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0191 60827cde248a7273a140d81912aaa88c 493 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 337 484 2.9E-6 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_1582 0adcec93acc5acc22ce6463736f1f5db 120 Pfam PF04892 VanZ like family 9 98 2.8E-9 T 14-10-2018 IPR006976 VanZ-like Theos_0640 0d9c45f352f9279ebddd3bf623cbdf58 100 Pfam PF01192 RNA polymerase Rpb6 12 73 1.3E-7 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Theos_0640 0d9c45f352f9279ebddd3bf623cbdf58 100 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 76 13.506 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0640 0d9c45f352f9279ebddd3bf623cbdf58 100 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 47 6.9E-8 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Theos_0640 0d9c45f352f9279ebddd3bf623cbdf58 100 SMART SM01409 8 75 6.2E-8 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Theos_0640 0d9c45f352f9279ebddd3bf623cbdf58 100 SUPERFAMILY SSF63562 1 94 3.49E-20 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Theos_0640 0d9c45f352f9279ebddd3bf623cbdf58 100 Gene3D G3DSA:3.90.940.10 1 99 2.3E-54 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Theos_1106 cbff99b07e176d77d17ad95f8bb57396 100 Pfam PF01909 Nucleotidyltransferase domain 20 85 2.7E-7 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Theos_1106 cbff99b07e176d77d17ad95f8bb57396 100 SUPERFAMILY SSF81301 7 97 8.18E-14 T 14-10-2018 Theos_1106 cbff99b07e176d77d17ad95f8bb57396 100 Gene3D G3DSA:3.30.460.10 3 100 3.3E-17 T 14-10-2018 Theos_2440 b696ae8ddd0fccec80af0ed1f49a316c 329 Gene3D G3DSA:3.40.190.10 24 322 4.1E-110 T 14-10-2018 Theos_2440 b696ae8ddd0fccec80af0ed1f49a316c 329 Gene3D G3DSA:3.40.190.10 103 214 4.1E-110 T 14-10-2018 Theos_2440 b696ae8ddd0fccec80af0ed1f49a316c 329 Pfam PF09084 NMT1/THI5 like 36 248 1.7E-25 T 14-10-2018 IPR015168 SsuA/THI5-like Theos_2440 b696ae8ddd0fccec80af0ed1f49a316c 329 SUPERFAMILY SSF53850 19 270 1.09E-44 T 14-10-2018 Theos_0112 2a56839ff2e530038651496f1f9a84dd 468 SUPERFAMILY SSF101960 35 465 1.44E-133 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Theos_0112 2a56839ff2e530038651496f1f9a84dd 468 Pfam PF01458 Uncharacterized protein family (UPF0051) 214 439 3.5E-71 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Theos_0112 2a56839ff2e530038651496f1f9a84dd 468 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 12 459 1.1E-214 T 14-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 Theos_2211 2353c35992b2b653742a96aba5219a8e 140 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 9 138 1.5E-8 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 Theos_0570 57ba34c7244c1eed5263498c9b51139c 406 Pfam PF00482 Type II secretion system (T2SS), protein F 272 395 1.8E-29 T 14-10-2018 IPR018076 Type II secretion system F domain Theos_0570 57ba34c7244c1eed5263498c9b51139c 406 Pfam PF00482 Type II secretion system (T2SS), protein F 70 192 2.2E-32 T 14-10-2018 IPR018076 Type II secretion system F domain Theos_0570 57ba34c7244c1eed5263498c9b51139c 406 Gene3D G3DSA:1.20.81.30 53 168 1.0E-34 T 14-10-2018 Theos_0570 57ba34c7244c1eed5263498c9b51139c 406 Gene3D G3DSA:1.20.81.30 255 367 2.1E-28 T 14-10-2018 Theos_0570 57ba34c7244c1eed5263498c9b51139c 406 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 164 192 - T 14-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 Theos_0570 57ba34c7244c1eed5263498c9b51139c 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 368 382 1.2E-18 T 14-10-2018 IPR003004 GspF/PilC family Theos_0570 57ba34c7244c1eed5263498c9b51139c 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 66 78 1.2E-18 T 14-10-2018 IPR003004 GspF/PilC family Theos_0570 57ba34c7244c1eed5263498c9b51139c 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 403 1.2E-18 T 14-10-2018 IPR003004 GspF/PilC family Theos_0570 57ba34c7244c1eed5263498c9b51139c 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 1.2E-18 T 14-10-2018 IPR003004 GspF/PilC family Theos_1423 39b9d322e880df318fb035034b389bd1 116 Pfam PF02627 Carboxymuconolactone decarboxylase family 47 110 2.0E-8 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Theos_1423 39b9d322e880df318fb035034b389bd1 116 Gene3D G3DSA:1.20.1290.10 1 116 4.1E-18 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Theos_1423 39b9d322e880df318fb035034b389bd1 116 SUPERFAMILY SSF69118 3 113 3.01E-18 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Theos_1777 059c78887a06b7c07dcf8b7ef855263d 428 Pfam PF02096 60Kd inner membrane protein 247 421 1.4E-56 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Theos_1777 059c78887a06b7c07dcf8b7ef855263d 428 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 246 421 6.1E-60 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Theos_1777 059c78887a06b7c07dcf8b7ef855263d 428 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 2 423 15.442 T 14-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 Theos_1226 fce38218aacf08e774f9696b476c8ba0 118 Pfam PF05685 Putative restriction endonuclease 17 94 3.0E-10 T 14-10-2018 IPR008538 Domain of unknown function DUF820 Theos_0061 effc0f3bc9aebc65a801188fe0cb9b89 251 Gene3D G3DSA:3.10.520.20 100 249 3.2E-33 T 14-10-2018 Theos_0061 effc0f3bc9aebc65a801188fe0cb9b89 251 SUPERFAMILY SSF143631 10 245 6.41E-45 T 14-10-2018 IPR003374 ApbE-like superfamily Theos_0061 effc0f3bc9aebc65a801188fe0cb9b89 251 Gene3D G3DSA:3.10.520.20 6 91 1.5E-9 T 14-10-2018 Theos_0061 effc0f3bc9aebc65a801188fe0cb9b89 251 Pfam PF02424 ApbE family 110 232 1.7E-27 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 Theos_0061 effc0f3bc9aebc65a801188fe0cb9b89 251 Pfam PF02424 ApbE family 16 89 4.7E-7 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 Theos_0128 8c2854fc5594fdfbcd945cd4025139ec 188 Gene3D G3DSA:3.40.630.30 31 177 2.8E-32 T 14-10-2018 Theos_0128 8c2854fc5594fdfbcd945cd4025139ec 188 Pfam PF00583 Acetyltransferase (GNAT) family 67 146 8.8E-13 T 14-10-2018 IPR000182 GNAT domain Theos_0128 8c2854fc5594fdfbcd945cd4025139ec 188 SUPERFAMILY SSF55729 17 152 2.33E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_2068 3dce94a01cabe5eb1d3d20734686b1b6 189 Gene3D G3DSA:1.20.910.10 4 188 9.2E-42 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 Theos_2068 3dce94a01cabe5eb1d3d20734686b1b6 189 SUPERFAMILY SSF48613 26 187 4.89E-34 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 Theos_0739 9e127cb6151e6b8e9a2af0064a96ffb3 229 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 8 223 8.0E-69 T 14-10-2018 IPR022493 Integral membrane YkoY Theos_0739 9e127cb6151e6b8e9a2af0064a96ffb3 229 Pfam PF03741 Integral membrane protein TerC family 10 182 5.0E-49 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 Theos_2271 67e10546f067537d226862204294184f 296 Gene3D G3DSA:1.25.10.10 4 106 5.2E-6 T 14-10-2018 IPR011989 Armadillo-like helical Theos_2271 67e10546f067537d226862204294184f 296 Gene3D G3DSA:1.25.10.10 116 296 5.6E-9 T 14-10-2018 IPR011989 Armadillo-like helical Theos_2271 67e10546f067537d226862204294184f 296 Pfam PF01816 Leucine rich repeat variant 259 281 3.4E-5 T 14-10-2018 IPR004830 Leucine rich repeat variant Theos_0361 a152aa662a767e0427bd8b8b28523993 142 Pfam PF02577 Bifunctional nuclease 5 130 1.3E-44 T 14-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 Theos_0361 a152aa662a767e0427bd8b8b28523993 142 Gene3D G3DSA:3.10.690.10 1 136 1.5E-47 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 Theos_0361 a152aa662a767e0427bd8b8b28523993 142 SUPERFAMILY SSF103256 6 131 8.24E-42 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 Theos_2004 cd2732af4b640261967b6b8a66f57f38 127 SUPERFAMILY SSF88723 4 127 8.97E-22 T 14-10-2018 IPR029060 PIN-like domain superfamily Theos_2004 cd2732af4b640261967b6b8a66f57f38 127 Pfam PF01850 PIN domain 4 121 3.3E-14 T 14-10-2018 IPR002716 PIN domain Theos_2004 cd2732af4b640261967b6b8a66f57f38 127 Gene3D G3DSA:3.40.50.1010 2 121 9.1E-10 T 14-10-2018 Theos_0679 e5c02be2482e91cae7ea05bd1c173872 310 Gene3D G3DSA:3.90.226.10 49 247 6.4E-65 T 14-10-2018 Theos_0679 e5c02be2482e91cae7ea05bd1c173872 310 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 48 253 1.2E-58 T 14-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 Theos_0679 e5c02be2482e91cae7ea05bd1c173872 310 Pfam PF01343 Peptidase family S49 104 254 2.7E-44 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 Theos_0679 e5c02be2482e91cae7ea05bd1c173872 310 Gene3D G3DSA:3.40.1750.20 144 210 6.4E-65 T 14-10-2018 Theos_0679 e5c02be2482e91cae7ea05bd1c173872 310 SUPERFAMILY SSF52096 38 239 7.69E-39 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_1846 2bcc44c22014159445725ac26a22f220 93 SUPERFAMILY SSF140663 4 91 5.89E-24 T 14-10-2018 IPR023203 TTHA0068-like superfamily Theos_1846 2bcc44c22014159445725ac26a22f220 93 Pfam PF03745 Domain of unknown function (DUF309) 4 54 2.1E-18 T 14-10-2018 IPR005500 Protein of unknown function DUF309 Theos_1846 2bcc44c22014159445725ac26a22f220 93 Gene3D G3DSA:1.20.58.500 2 93 3.3E-32 T 14-10-2018 Theos_1139 1fe33fca57f2ef3b2720882dd92572e2 186 Pfam PF03351 DOMON domain 43 162 2.1E-17 T 14-10-2018 IPR005018 DOMON domain Theos_1139 1fe33fca57f2ef3b2720882dd92572e2 186 Pfam PF09459 Ethylbenzene dehydrogenase 74 157 5.1E-8 T 14-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 Theos_1887 fe211c897a8d84d6c4f0e0d431f2e0da 277 SUPERFAMILY SSF103481 40 134 3.27E-6 T 14-10-2018 Theos_1887 fe211c897a8d84d6c4f0e0d431f2e0da 277 Pfam PF00892 EamA-like transporter family 7 131 7.9E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_1887 fe211c897a8d84d6c4f0e0d431f2e0da 277 Pfam PF00892 EamA-like transporter family 142 271 2.5E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_1887 fe211c897a8d84d6c4f0e0d431f2e0da 277 SUPERFAMILY SSF103481 177 275 7.98E-17 T 14-10-2018 Theos_2490 5f578ea0173358c3e4f7b473fdca6e03 71 Gene3D G3DSA:3.10.450.450 1 66 3.5E-26 T 14-10-2018 Theos_0848 5c1edf1a256e01bc2153c881060a0588 875 SUPERFAMILY SSF117074 697 753 4.45E-8 T 14-10-2018 Theos_0848 5c1edf1a256e01bc2153c881060a0588 875 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 449 486 5.1E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0848 5c1edf1a256e01bc2153c881060a0588 875 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 562 610 9.3E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0848 5c1edf1a256e01bc2153c881060a0588 875 Pfam PF01345 Domain of unknown function DUF11 183 289 1.1E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0848 5c1edf1a256e01bc2153c881060a0588 875 Pfam PF01345 Domain of unknown function DUF11 560 663 2.8E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0848 5c1edf1a256e01bc2153c881060a0588 875 Pfam PF01345 Domain of unknown function DUF11 439 531 2.1E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 Theos_0848 5c1edf1a256e01bc2153c881060a0588 875 Gene3D G3DSA:2.60.40.10 696 768 1.1E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold Theos_0624 573f210247cab54ee61ef8080baae716 280 SUPERFAMILY SSF103481 182 278 9.55E-12 T 14-10-2018 Theos_0624 573f210247cab54ee61ef8080baae716 280 SUPERFAMILY SSF103481 39 135 1.96E-10 T 14-10-2018 Theos_0624 573f210247cab54ee61ef8080baae716 280 Pfam PF00892 EamA-like transporter family 146 276 2.6E-22 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_0624 573f210247cab54ee61ef8080baae716 280 Pfam PF00892 EamA-like transporter family 9 132 2.1E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_0703 95fc460b1d2863830f7a16495a2b2885 428 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 7 420 15.886 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 Theos_0703 95fc460b1d2863830f7a16495a2b2885 428 Pfam PF00361 Proton-conducting membrane transporter 102 370 4.4E-59 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Theos_2281 9efc9fbd22cef7a42fd7e076c2c342d4 911 SUPERFAMILY SSF52490 8 215 5.49E-5 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Theos_2281 9efc9fbd22cef7a42fd7e076c2c342d4 911 Pfam PF13809 Tubulin like 10 342 1.3E-73 T 14-10-2018 IPR025904 Tubulin-like Theos_0568 576bd3c0066a749d88acb638058fe9c5 190 Gene3D G3DSA:3.90.870.10 1 187 1.0E-47 T 14-10-2018 Theos_0568 576bd3c0066a749d88acb638058fe9c5 190 Pfam PF01300 Telomere recombination 7 175 6.8E-41 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 Theos_0568 576bd3c0066a749d88acb638058fe9c5 190 SUPERFAMILY SSF55821 9 181 1.13E-41 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Theos_0500 79c2541f2235be51bc4acdc9d8b1ac1b 251 SUPERFAMILY SSF51182 2 237 9.45E-55 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Theos_0500 79c2541f2235be51bc4acdc9d8b1ac1b 251 Gene3D G3DSA:2.60.120.10 24 165 1.0E-45 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_1060 5e1ba88b078d6807c0d02d6149474cdb 98 Pfam PF02311 AraC-like ligand binding domain 45 85 1.6E-4 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Theos_1060 5e1ba88b078d6807c0d02d6149474cdb 98 SUPERFAMILY SSF51182 15 96 3.26E-6 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Theos_1060 5e1ba88b078d6807c0d02d6149474cdb 98 Gene3D G3DSA:2.60.120.10 1 95 2.0E-10 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_1917 d06f264faf8d21fbe92379319d1a6014 261 Pfam PF05258 Protein of unknown function (DUF721) 15 99 7.2E-17 T 14-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 Theos_0798 9f5195527deca2fbaca76719ae82a75c 317 Gene3D G3DSA:3.20.20.140 1 317 9.9E-62 T 14-10-2018 Theos_0798 9f5195527deca2fbaca76719ae82a75c 317 SUPERFAMILY SSF51556 1 315 7.99E-55 T 14-10-2018 IPR032466 Metal-dependent hydrolase Theos_0798 9f5195527deca2fbaca76719ae82a75c 317 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 300 2.4E-48 T 14-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 Theos_2129 4b504573b360217e0e9cea12b846dc7d 294 Pfam PF00892 EamA-like transporter family 154 289 1.4E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_2129 4b504573b360217e0e9cea12b846dc7d 294 Pfam PF00892 EamA-like transporter family 11 139 1.9E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_2129 4b504573b360217e0e9cea12b846dc7d 294 SUPERFAMILY SSF103481 49 143 5.1E-15 T 14-10-2018 Theos_2129 4b504573b360217e0e9cea12b846dc7d 294 SUPERFAMILY SSF103481 193 293 3.01E-11 T 14-10-2018 Theos_0908 ba7f50a934e51aaa9a101324b94adb36 226 Pfam PF04298 Putative neutral zinc metallopeptidase 6 220 9.4E-85 T 14-10-2018 IPR007395 Putative neutral zinc metallopeptidase Theos_1062 e90e305b4782deebe608bd17dba71033 361 Pfam PF14256 YwiC-like protein 14 144 1.4E-21 T 14-10-2018 IPR025576 YwiC-like protein Theos_1454 ae903c781f139d1c0fc6c2da61e15b88 451 SUPERFAMILY SSF51905 1 434 3.5E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1454 ae903c781f139d1c0fc6c2da61e15b88 451 Gene3D G3DSA:3.50.50.60 1 71 2.5E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Theos_1454 ae903c781f139d1c0fc6c2da61e15b88 451 Pfam PF01593 Flavin containing amine oxidoreductase 1 270 8.6E-16 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 Theos_2301 e337f0f0e0d35411cd2e016c100baa62 222 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 22 216 2.6E-58 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 Theos_2301 e337f0f0e0d35411cd2e016c100baa62 222 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 21 192 1.4E-45 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 Theos_2301 e337f0f0e0d35411cd2e016c100baa62 222 SUPERFAMILY SSF52402 3 181 4.19E-48 T 14-10-2018 Theos_2301 e337f0f0e0d35411cd2e016c100baa62 222 PIRSF PIRSF000857 2 221 3.4E-70 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 Theos_2301 e337f0f0e0d35411cd2e016c100baa62 222 Gene3D G3DSA:3.40.50.620 1 221 2.5E-63 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_0791 eeab4a8e62a0eb15ce584dad1e4b77fa 188 Pfam PF02698 DUF218 domain 24 145 1.4E-27 T 14-10-2018 IPR003848 Domain of unknown function DUF218 Theos_2041 f752e03b5937e785d9f897db63a2b987 187 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 181 9.0E-71 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Theos_2041 f752e03b5937e785d9f897db63a2b987 187 Gene3D G3DSA:1.20.1200.10 12 187 6.9E-65 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Theos_2041 f752e03b5937e785d9f897db63a2b987 187 Pfam PF01923 Cobalamin adenosyltransferase 3 170 6.6E-65 T 14-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Theos_2041 f752e03b5937e785d9f897db63a2b987 187 SUPERFAMILY SSF89028 1 182 5.49E-66 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Theos_2041 f752e03b5937e785d9f897db63a2b987 187 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 181 3.5E-65 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Theos_1316 af2aaa0496d52439a24c4338826886fb 456 Gene3D G3DSA:3.40.50.300 4 266 6.6E-26 T 14-10-2018 Theos_1316 af2aaa0496d52439a24c4338826886fb 456 Pfam PF13481 AAA domain 8 176 6.0E-24 T 14-10-2018 Theos_1316 af2aaa0496d52439a24c4338826886fb 456 SUPERFAMILY SSF52540 20 229 2.13E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0382 9d8fefda2af4e0c35ffdbcba4629f8be 121 Pfam PF02627 Carboxymuconolactone decarboxylase family 25 107 3.4E-19 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Theos_0382 9d8fefda2af4e0c35ffdbcba4629f8be 121 Gene3D G3DSA:1.20.1290.10 1 114 2.3E-34 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Theos_0382 9d8fefda2af4e0c35ffdbcba4629f8be 121 SUPERFAMILY SSF69118 2 118 1.96E-30 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Theos_1563 03d09fcc2d28c3c2e59436b90ff37799 307 Pfam PF01619 Proline dehydrogenase 45 292 4.2E-27 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 Theos_1563 03d09fcc2d28c3c2e59436b90ff37799 307 Gene3D G3DSA:3.20.20.530 18 307 3.7E-92 T 14-10-2018 Theos_1563 03d09fcc2d28c3c2e59436b90ff37799 307 SUPERFAMILY SSF51730 38 302 7.06E-67 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like Theos_1563 03d09fcc2d28c3c2e59436b90ff37799 307 PIRSF PIRSF000196 3 306 4.1E-109 T 14-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 Theos_0754 b4f31577550b1a36da8a906487718480 320 Gene3D G3DSA:3.30.565.10 196 320 1.2E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0754 b4f31577550b1a36da8a906487718480 320 SUPERFAMILY SSF55874 200 320 4.58E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Theos_0754 b4f31577550b1a36da8a906487718480 320 SMART SM00387 230 320 0.0018 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0754 b4f31577550b1a36da8a906487718480 320 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 231 320 2.8E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Theos_0754 b4f31577550b1a36da8a906487718480 320 Pfam PF07730 Histidine kinase 136 193 3.7E-11 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Theos_0268 c563e1025ea33aec9389dbc084fc0af0 123 Pfam PF04519 Polymer-forming cytoskeletal 13 108 4.3E-23 T 14-10-2018 IPR007607 Bactofilin A/B Theos_0323 b5fc278b21f88dc7b174f2d8ce6ae75f 56 Pfam PF04255 Protein of unknown function (DUF433) 6 44 2.9E-12 T 14-10-2018 IPR007367 Protein of unknown function DUF433 Theos_0323 b5fc278b21f88dc7b174f2d8ce6ae75f 56 Gene3D G3DSA:1.10.10.10 3 56 1.8E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Theos_0323 b5fc278b21f88dc7b174f2d8ce6ae75f 56 SUPERFAMILY SSF46689 6 53 8.78E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Theos_0831 15a84e104f665865e2c8e8d46dd44eef 134 Pfam PF03750 Csm2 Type III-A 19 128 6.8E-20 T 14-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A Theos_0831 15a84e104f665865e2c8e8d46dd44eef 134 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 36 132 7.7E-22 T 14-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A Theos_0742 b4c0b508eb9bd8c68144749d7e6ea04a 289 SUPERFAMILY SSF53098 16 284 2.28E-50 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_2510 7b2469eda6fa906d81b81b634627ab45 203 Gene3D G3DSA:3.90.70.10 36 172 2.8E-19 T 14-10-2018 Theos_2510 7b2469eda6fa906d81b81b634627ab45 203 Pfam PF03412 Peptidase C39 family 33 169 1.3E-13 T 14-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 Theos_1233 fbbd8b907418e968328a5ef65c3f7854 252 Pfam PF03741 Integral membrane protein TerC family 14 202 7.8E-50 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 Theos_0719 1ce51cfae592beb95ab1267f0e2ec8e0 210 Pfam PF04098 Rad52/22 family double-strand break repair protein 4 135 9.8E-19 T 14-10-2018 IPR007232 DNA repair protein Rad52/59/22 GO:0006281|GO:0006310 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938 Theos_0719 1ce51cfae592beb95ab1267f0e2ec8e0 210 Gene3D G3DSA:3.30.390.80 1 133 4.9E-6 T 14-10-2018 Theos_1061 6b0e4fb18b0e7a082966a12e2d2a660b 124 SUPERFAMILY SSF81442 6 123 4.19E-6 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1061 6b0e4fb18b0e7a082966a12e2d2a660b 124 Gene3D G3DSA:1.20.210.10 31 111 1.7E-6 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1903 d396bd07ddb8b6d7a3c521ac3de48400 482 Pfam PF09992 Phosphodiester glycosidase 371 479 1.1E-17 T 14-10-2018 IPR018711 Phosphodiester glycosidase Theos_1373 13035493670189ea19994ce3d20248ad 287 SUPERFAMILY SSF53807 11 285 2.11E-71 T 14-10-2018 Theos_1373 13035493670189ea19994ce3d20248ad 287 PRINTS PR00690 Adhesin family signature 49 62 2.3E-13 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Theos_1373 13035493670189ea19994ce3d20248ad 287 PRINTS PR00690 Adhesin family signature 62 79 2.3E-13 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Theos_1373 13035493670189ea19994ce3d20248ad 287 PRINTS PR00690 Adhesin family signature 180 201 2.3E-13 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Theos_1373 13035493670189ea19994ce3d20248ad 287 PRINTS PR00690 Adhesin family signature 18 36 2.3E-13 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Theos_1373 13035493670189ea19994ce3d20248ad 287 Gene3D G3DSA:3.40.50.1980 19 170 1.7E-45 T 14-10-2018 Theos_1373 13035493670189ea19994ce3d20248ad 287 Gene3D G3DSA:3.40.50.1980 185 286 5.6E-23 T 14-10-2018 Theos_1373 13035493670189ea19994ce3d20248ad 287 PRINTS PR00691 Adhesin B signature 62 81 1.2E-17 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Theos_1373 13035493670189ea19994ce3d20248ad 287 PRINTS PR00691 Adhesin B signature 43 61 1.2E-17 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Theos_1373 13035493670189ea19994ce3d20248ad 287 PRINTS PR00691 Adhesin B signature 18 39 1.2E-17 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Theos_1373 13035493670189ea19994ce3d20248ad 287 PRINTS PR00691 Adhesin B signature 126 145 1.2E-17 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Theos_1373 13035493670189ea19994ce3d20248ad 287 PRINTS PR00691 Adhesin B signature 268 286 1.2E-17 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Theos_1373 13035493670189ea19994ce3d20248ad 287 Pfam PF01297 Zinc-uptake complex component A periplasmic 21 285 3.7E-67 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 Theos_0372 9bfb976d693ed79b55b509c5a9d58227 205 Pfam PF03006 Haemolysin-III related 3 197 3.6E-35 T 14-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 Theos_0372 9bfb976d693ed79b55b509c5a9d58227 205 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 4 202 3.8E-54 T 14-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 Theos_1204 cfbba5a345f2cdfabe96c1340200489a 219 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 215 32.829 T 14-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 Theos_1204 cfbba5a345f2cdfabe96c1340200489a 219 PIRSF PIRSF001357 1 217 1.7E-70 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Theos_1204 cfbba5a345f2cdfabe96c1340200489a 219 Pfam PF01791 DeoC/LacD family aldolase 14 208 3.5E-11 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Theos_1204 cfbba5a345f2cdfabe96c1340200489a 219 Gene3D G3DSA:3.20.20.70 1 218 1.1E-83 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_1204 cfbba5a345f2cdfabe96c1340200489a 219 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 4 210 3.6E-65 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Theos_1204 cfbba5a345f2cdfabe96c1340200489a 219 SMART SM01133 2 213 1.2E-77 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Theos_1204 cfbba5a345f2cdfabe96c1340200489a 219 SUPERFAMILY SSF51569 2 212 1.36E-71 T 14-10-2018 Theos_0724 c99dccb9f6c238d21236faadb7440897 630 SMART SM00028 315 347 28.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0724 c99dccb9f6c238d21236faadb7440897 630 SMART SM00028 247 280 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0724 c99dccb9f6c238d21236faadb7440897 630 SMART SM00028 281 314 0.25 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Theos_0724 c99dccb9f6c238d21236faadb7440897 630 Gene3D G3DSA:1.25.40.10 225 408 2.1E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0724 c99dccb9f6c238d21236faadb7440897 630 SUPERFAMILY SSF48452 241 396 7.34E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0724 c99dccb9f6c238d21236faadb7440897 630 Pfam PF13432 Tetratricopeptide repeat 256 314 1.1E-8 T 14-10-2018 Theos_0914 f9e5fe84b37c3d027dc3638536016627 379 Gene3D G3DSA:3.40.630.40 199 379 2.6E-20 T 14-10-2018 Theos_0914 f9e5fe84b37c3d027dc3638536016627 379 SUPERFAMILY SSF53187 199 378 1.22E-20 T 14-10-2018 Theos_0914 f9e5fe84b37c3d027dc3638536016627 379 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 201 375 6.6E-16 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Theos_0815 17d79960776d770c37f4667725e0e904 104 Pfam PF16999 Vacuolar (H+)-ATPase G subunit 1 104 2.2E-27 T 14-10-2018 Theos_2312 682927c01f5fbeb29ecc95a5241e7f4b 107 Gene3D G3DSA:3.30.110.70 2 106 1.3E-43 T 14-10-2018 Theos_2312 682927c01f5fbeb29ecc95a5241e7f4b 107 SUPERFAMILY SSF117782 1 106 1.7E-38 T 14-10-2018 IPR035439 UPF0145 domain superfamily Theos_2312 682927c01f5fbeb29ecc95a5241e7f4b 107 Pfam PF01906 Putative heavy-metal-binding 1 104 3.2E-40 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 Theos_2312 682927c01f5fbeb29ecc95a5241e7f4b 107 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 25.417 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 Theos_2102 6bda06535dfa49ee96beaba95ded88cf 132 SUPERFAMILY SSF55486 2 107 3.66E-26 T 14-10-2018 Theos_2102 6bda06535dfa49ee96beaba95ded88cf 132 Pfam PF06262 Zincin-like metallopeptidase 25 118 7.2E-20 T 14-10-2018 IPR010428 Zincin-like metallopeptidase Theos_2102 6bda06535dfa49ee96beaba95ded88cf 132 Gene3D G3DSA:3.30.2010.20 1 130 1.6E-44 T 14-10-2018 IPR038555 Zincin-like metallopeptidase superfamily Theos_2444 4f82a7739508bba497a8306a7bc4de6d 396 Gene3D G3DSA:3.40.50.300 11 157 2.1E-6 T 14-10-2018 Theos_2444 4f82a7739508bba497a8306a7bc4de6d 396 Pfam PF13173 AAA domain 29 155 7.7E-18 T 14-10-2018 Theos_2444 4f82a7739508bba497a8306a7bc4de6d 396 Pfam PF13635 Domain of unknown function (DUF4143) 200 356 4.1E-19 T 14-10-2018 IPR025420 Domain of unknown function DUF4143 Theos_2444 4f82a7739508bba497a8306a7bc4de6d 396 SUPERFAMILY SSF52540 17 181 1.48E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_2009 dc6660db4fed7e41ede0c29e15cc36eb 283 SUPERFAMILY SSF55729 155 274 3.6E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_2009 dc6660db4fed7e41ede0c29e15cc36eb 283 Gene3D G3DSA:3.40.630.30 1 283 2.4E-31 T 14-10-2018 Theos_2009 dc6660db4fed7e41ede0c29e15cc36eb 283 SUPERFAMILY SSF55729 1 131 6.85E-10 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Theos_2009 dc6660db4fed7e41ede0c29e15cc36eb 283 Pfam PF13673 Acetyltransferase (GNAT) domain 173 270 3.7E-17 T 14-10-2018 IPR000182 GNAT domain Theos_1483 a66085bfbfb7cb44d0b0a3b7628c6c12 151 Pfam PF02681 Divergent PAP2 family 5 139 3.1E-47 T 14-10-2018 IPR003832 Protein of unknown function DUF212 Theos_1180 a6d892cc604148493ed9c03172c88186 201 Pfam PF13470 PIN domain 8 119 2.7E-8 T 14-10-2018 IPR002716 PIN domain Theos_1679 138eafe1bb692600a83ce5c4356d22ed 152 Pfam PF02643 Uncharacterized ACR, COG1430 38 141 3.9E-32 T 14-10-2018 IPR003795 Protein of unknown function DUF192 Theos_1679 138eafe1bb692600a83ce5c4356d22ed 152 Gene3D G3DSA:2.60.120.1140 14 142 1.2E-38 T 14-10-2018 IPR038695 Saro_0823-like superfamily Theos_1766 6dc4021f584b49e95205de59de8fb459 268 SUPERFAMILY SSF81345 4 261 1.22E-28 T 14-10-2018 IPR037294 ABC transporter, BtuC-like Theos_1766 6dc4021f584b49e95205de59de8fb459 268 Pfam PF00950 ABC 3 transport family 7 260 1.1E-62 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 Theos_1414 4051cfec3c027085b66fccb6e66723ae 216 SUPERFAMILY SSF117070 4 127 1.96E-10 T 14-10-2018 Theos_2197 f3c895038ea478218a38b595f90e3444 163 Gene3D G3DSA:2.20.28.160 1 48 6.1E-7 T 14-10-2018 Theos_0456 6071c5f912f30e85288582e4c2e129db 221 Gene3D G3DSA:1.20.5.1230 8 208 3.2E-16 T 14-10-2018 Theos_0456 6071c5f912f30e85288582e4c2e129db 221 SUPERFAMILY SSF58113 9 196 5.23E-13 T 14-10-2018 Theos_1256 38e7c2277c70b4214cf29f93157cb72b 129 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 23 97 3.1E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1256 38e7c2277c70b4214cf29f93157cb72b 129 Gene3D G3DSA:1.10.760.10 20 129 1.1E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1256 38e7c2277c70b4214cf29f93157cb72b 129 SUPERFAMILY SSF46626 2 102 5.24E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1084 9629d0f1714e822e2bcf259790a79c78 241 Pfam PF00005 ABC transporter 6 154 3.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Theos_1084 9629d0f1714e822e2bcf259790a79c78 241 SMART SM00382 15 202 3.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain Theos_1084 9629d0f1714e822e2bcf259790a79c78 241 SUPERFAMILY SSF52540 4 216 1.09E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_1084 9629d0f1714e822e2bcf259790a79c78 241 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Theos_1084 9629d0f1714e822e2bcf259790a79c78 241 Gene3D G3DSA:3.40.50.300 2 232 1.2E-63 T 14-10-2018 Theos_2177 27d5f0ac2f5287ddecc052657f8b38d7 155 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 132 8.5E-10 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Theos_2177 27d5f0ac2f5287ddecc052657f8b38d7 155 SUPERFAMILY SSF54534 2 136 2.95E-34 T 14-10-2018 Theos_2177 27d5f0ac2f5287ddecc052657f8b38d7 155 Gene3D G3DSA:3.10.50.40 1 155 3.0E-54 T 14-10-2018 Theos_1275 ab55df82fe7f072e8a74a281481162cd 69 Gene3D G3DSA:3.30.70.100 2 64 1.6E-8 T 14-10-2018 Theos_0449 1c343b266bd4a13ff82fe5b3d671de1e 366 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 141 357 1.5E-44 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Theos_0449 1c343b266bd4a13ff82fe5b3d671de1e 366 SMART SM00646 204 357 1.8E-32 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Theos_0449 1c343b266bd4a13ff82fe5b3d671de1e 366 SUPERFAMILY SSF53187 139 360 3.77E-48 T 14-10-2018 Theos_0449 1c343b266bd4a13ff82fe5b3d671de1e 366 Gene3D G3DSA:3.40.630.40 131 365 1.5E-56 T 14-10-2018 Theos_0443 b0797c239c531a6088faedaa0b0822cd 363 SUPERFAMILY SSF53098 17 324 1.44E-26 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_0443 b0797c239c531a6088faedaa0b0822cd 363 Pfam PF01609 Transposase DDE domain 144 298 8.2E-16 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Theos_2417 b0797c239c531a6088faedaa0b0822cd 363 SUPERFAMILY SSF53098 17 324 1.44E-26 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_2417 b0797c239c531a6088faedaa0b0822cd 363 Pfam PF01609 Transposase DDE domain 144 298 8.2E-16 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Theos_1389 3a2cf6a40c2228f04a4cda2a680bea4f 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 330 9.3E-42 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_0012 7587c5396e5ddec3d7dad55d422b8c12 153 SUPERFAMILY SSF109604 39 153 4.4E-9 T 14-10-2018 Theos_2342 b30413aa845acdb15e0b104de0e8ba70 238 Pfam PF00535 Glycosyl transferase family 2 8 115 1.7E-16 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Theos_2342 b30413aa845acdb15e0b104de0e8ba70 238 Gene3D G3DSA:3.90.550.10 1 221 1.9E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_2342 b30413aa845acdb15e0b104de0e8ba70 238 SUPERFAMILY SSF53448 4 204 1.13E-35 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_2220 e6a4376c14e276292412137ffc5afb7e 170 Gene3D G3DSA:3.10.450.50 2 170 1.6E-60 T 14-10-2018 Theos_2220 e6a4376c14e276292412137ffc5afb7e 170 SUPERFAMILY SSF54427 5 170 8.98E-48 T 14-10-2018 IPR032710 NTF2-like domain superfamily Theos_2220 e6a4376c14e276292412137ffc5afb7e 170 Pfam PF00866 Ring hydroxylating beta subunit 13 162 2.6E-43 T 14-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 Theos_1406 b0d1a751457ab5f751967e2624a4c008 325 Pfam PF12127 SigmaW regulon antibacterial 7 317 5.9E-165 T 14-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity Theos_1406 b0d1a751457ab5f751967e2624a4c008 325 Hamap MF_01562 UPF0365 protein . 1 321 47.145 T 14-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity Theos_2052 1dba9e6b304ae7ad9212d9e5ea98f536 530 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 368 528 4.8E-44 T 14-10-2018 IPR000160 GGDEF domain Theos_2052 1dba9e6b304ae7ad9212d9e5ea98f536 530 SMART SM00267 356 530 9.9E-55 T 14-10-2018 IPR000160 GGDEF domain Theos_2052 1dba9e6b304ae7ad9212d9e5ea98f536 530 SUPERFAMILY SSF55073 374 529 4.39E-42 T 14-10-2018 IPR029787 Nucleotide cyclase Theos_2052 1dba9e6b304ae7ad9212d9e5ea98f536 530 Gene3D G3DSA:3.30.70.270 354 530 9.5E-49 T 14-10-2018 Theos_2052 1dba9e6b304ae7ad9212d9e5ea98f536 530 Pfam PF00990 Diguanylate cyclase, GGDEF domain 369 526 1.6E-39 T 14-10-2018 IPR000160 GGDEF domain Theos_2377 8e6439ec3eb856989db44f3a3fc32cbe 401 SUPERFAMILY SSF50969 58 396 2.51E-11 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Theos_0635 75f7b956a50e67c902a63faea754e8a7 481 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 28 463 1.7E-84 T 14-10-2018 IPR011199 Bacillithiol biosynthesis BshC Theos_0635 75f7b956a50e67c902a63faea754e8a7 481 Pfam PF10079 Bacillithiol biosynthesis BshC 29 461 6.8E-70 T 14-10-2018 IPR011199 Bacillithiol biosynthesis BshC Theos_2021 16f5e5114abc9abe0435ac3f2432832c 725 Gene3D G3DSA:1.10.8.630 20 124 1.1E-14 T 14-10-2018 Theos_2021 16f5e5114abc9abe0435ac3f2432832c 725 Hamap MF_00983 Probable primosomal protein N' [priA]. 23 719 16.907 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 Theos_0694 ae1e263b7eadee69c1ca4dd1d7bd51b1 140 Pfam PF06146 Phosphate-starvation-inducible E 58 125 4.7E-10 T 14-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like Theos_0222 f9a6a4450a9d52c470bc9d8050b71c4f 410 Pfam PF13552 Protein of unknown function (DUF4127) 25 132 2.2E-11 T 14-10-2018 IPR025394 Protein of unknown function DUF4127 Theos_0222 f9a6a4450a9d52c470bc9d8050b71c4f 410 Pfam PF13552 Protein of unknown function (DUF4127) 178 332 2.8E-24 T 14-10-2018 IPR025394 Protein of unknown function DUF4127 Theos_2151 d93a3dae3a0ea4c5afaf3883e4c88aa4 472 SUPERFAMILY SSF102114 138 440 2.09E-45 T 14-10-2018 Theos_2151 d93a3dae3a0ea4c5afaf3883e4c88aa4 472 Gene3D G3DSA:3.20.20.70 137 432 1.4E-41 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_2151 d93a3dae3a0ea4c5afaf3883e4c88aa4 472 Pfam PF04055 Radical SAM superfamily 149 300 3.5E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Theos_1791 67aaaeadbc3a515191ec5a56c3aa446c 161 Gene3D G3DSA:1.10.490.110 18 161 8.3E-67 T 14-10-2018 Theos_1791 67aaaeadbc3a515191ec5a56c3aa446c 161 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 34 158 1.8E-41 T 14-10-2018 IPR018727 Protein of unknown function DUF2267 Theos_1533 b9d57b1df9c18662674d242f420ed33f 527 SUPERFAMILY SSF56112 73 291 2.53E-25 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Theos_1533 b9d57b1df9c18662674d242f420ed33f 527 Pfam PF03109 ABC1 family 97 209 3.7E-26 T 14-10-2018 IPR004147 UbiB domain Theos_2389 fd3c86076f530b59ac97f93941d835b7 419 SUPERFAMILY SSF50952 67 188 1.83E-5 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Theos_2389 fd3c86076f530b59ac97f93941d835b7 419 Pfam PF13449 Esterase-like activity of phytase 63 385 6.1E-66 T 14-10-2018 IPR027372 Phytase-like domain Theos_2389 fd3c86076f530b59ac97f93941d835b7 419 SUPERFAMILY SSF75011 153 354 2.48E-5 T 14-10-2018 Theos_0126 1b4639aac486c5e82e043e8bddad47d0 72 SUPERFAMILY SSF54786 6 71 6.28E-15 T 14-10-2018 Theos_0126 1b4639aac486c5e82e043e8bddad47d0 72 Gene3D G3DSA:3.30.920.30 5 72 7.1E-12 T 14-10-2018 IPR038570 HicA superfamily Theos_0126 1b4639aac486c5e82e043e8bddad47d0 72 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 11 65 3.0E-10 T 14-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Theos_1142 1870d1026fa9026dff77a8e35da29f2b 306 Pfam PF04463 Protein of unknown function (DUF523) 9 147 1.0E-28 T 14-10-2018 IPR007553 Domain of unknown function DUF523 Theos_1142 1870d1026fa9026dff77a8e35da29f2b 306 Pfam PF08349 Protein of unknown function (DUF1722) 186 299 5.4E-27 T 14-10-2018 IPR013560 Domain of unknown function DUF1722 Theos_1210 129237617ee13c477f6cda29dd7392b9 176 Gene3D G3DSA:2.160.20.70 67 176 2.4E-37 T 14-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 Theos_1210 129237617ee13c477f6cda29dd7392b9 176 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 73 169 3.6E-30 T 14-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 Theos_1210 129237617ee13c477f6cda29dd7392b9 176 SUPERFAMILY SSF63848 70 172 4.71E-30 T 14-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 Theos_0412 901c4486168745f19b4fa9dc8de6b477 356 SUPERFAMILY SSF53383 13 354 7.58E-80 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Theos_0412 901c4486168745f19b4fa9dc8de6b477 356 Pfam PF00155 Aminotransferase class I and II 32 349 5.5E-35 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Theos_0412 901c4486168745f19b4fa9dc8de6b477 356 Gene3D G3DSA:3.40.640.10 50 259 1.2E-97 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Theos_0412 901c4486168745f19b4fa9dc8de6b477 356 Gene3D G3DSA:3.90.1150.10 11 348 1.2E-97 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Theos_2111 16bb3256fe00579ac594bfa9a43134f5 178 Gene3D G3DSA:3.40.50.2020 1 178 3.8E-60 T 14-10-2018 Theos_2111 16bb3256fe00579ac594bfa9a43134f5 178 SUPERFAMILY SSF53271 10 177 1.05E-48 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Theos_2111 16bb3256fe00579ac594bfa9a43134f5 178 Pfam PF00156 Phosphoribosyl transferase domain 13 138 4.9E-24 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Theos_2111 16bb3256fe00579ac594bfa9a43134f5 178 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 173 2.5E-62 T 14-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 Theos_0244 b4236daf8f395ba39fb0753916bf8cfe 330 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 66 261 2.0E-59 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 Theos_0244 b4236daf8f395ba39fb0753916bf8cfe 330 Gene3D G3DSA:3.40.50.450 1 264 2.0E-83 T 14-10-2018 Theos_0244 b4236daf8f395ba39fb0753916bf8cfe 330 Pfam PF02481 DNA recombination-mediator protein A 56 253 2.0E-66 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 Theos_0244 b4236daf8f395ba39fb0753916bf8cfe 330 SUPERFAMILY SSF102405 67 263 7.17E-39 T 14-10-2018 Theos_1296 30b78f8625f6bf085efcb9c508bd9171 406 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 393 5.6E-48 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_1183 df35678a866f507be9b14dc034a92d3d 104 Pfam PF06305 Lipopolysaccharide assembly protein A domain 37 85 1.4E-7 T 14-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 Theos_1558 f858dd1073f588b29dfe93094cf483c6 369 Pfam PF01979 Amidohydrolase family 59 366 4.2E-29 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Theos_1558 f858dd1073f588b29dfe93094cf483c6 369 SUPERFAMILY SSF51556 63 353 3.29E-62 T 14-10-2018 IPR032466 Metal-dependent hydrolase Theos_1558 f858dd1073f588b29dfe93094cf483c6 369 SUPERFAMILY SSF51338 7 78 9.5E-16 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Theos_1558 f858dd1073f588b29dfe93094cf483c6 369 Gene3D G3DSA:3.20.20.140 16 356 4.8E-92 T 14-10-2018 Theos_1558 f858dd1073f588b29dfe93094cf483c6 369 Gene3D G3DSA:2.30.40.10 7 364 4.8E-92 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Theos_2046 b4751ad4fb5319a472d59bf27bdb8c02 61 Gene3D G3DSA:1.10.1220.10 5 53 8.9E-9 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Theos_2046 b4751ad4fb5319a472d59bf27bdb8c02 61 SUPERFAMILY SSF47598 6 54 1.06E-10 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Theos_0723 b8c87633bea715ea564617d4075f2ab1 417 SUPERFAMILY SSF52317 212 377 1.12E-6 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Theos_0601 1d6bfb4375e033cb2d3eae04170b61c8 132 Pfam PF02675 S-adenosylmethionine decarboxylase 10 117 3.8E-21 T 14-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 Theos_0601 1d6bfb4375e033cb2d3eae04170b61c8 132 Gene3D G3DSA:3.60.90.10 2 127 7.1E-23 T 14-10-2018 Theos_0601 1d6bfb4375e033cb2d3eae04170b61c8 132 SUPERFAMILY SSF56276 6 118 1.26E-24 T 14-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 Theos_1065 cab56c3de73caf6cbac087cfc98b67f1 353 SMART SM01007 185 350 1.5E-4 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal Theos_1065 cab56c3de73caf6cbac087cfc98b67f1 353 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 196 283 3.0E-11 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal Theos_1065 cab56c3de73caf6cbac087cfc98b67f1 353 SUPERFAMILY SSF53639 193 343 1.35E-23 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Theos_1065 cab56c3de73caf6cbac087cfc98b67f1 353 Gene3D G3DSA:3.40.225.10 188 346 4.2E-22 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Theos_1343 9116ec5f58c9041737a612f6e55042a8 173 Gene3D G3DSA:3.90.1570.10 2 166 2.0E-11 T 14-10-2018 Theos_1343 9116ec5f58c9041737a612f6e55042a8 173 Pfam PF05685 Putative restriction endonuclease 19 165 4.0E-25 T 14-10-2018 IPR008538 Domain of unknown function DUF820 Theos_1343 9116ec5f58c9041737a612f6e55042a8 173 SUPERFAMILY SSF52980 5 149 6.43E-17 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_2049 ecaf63899725b0270bb1493702239ff0 67 Gene3D G3DSA:3.30.160.250 1 67 1.1E-27 T 14-10-2018 Theos_2049 ecaf63899725b0270bb1493702239ff0 67 SUPERFAMILY SSF143100 4 53 8.76E-11 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like Theos_2006 bc064fecadfebdd038a7fe7a3b03c4ff 321 SUPERFAMILY SSF48452 228 306 6.01E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Theos_0339 e83ec62eeaec3176b706c2f292de0b24 209 Pfam PF03692 Putative zinc- or iron-chelating domain 28 113 2.0E-6 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein Theos_0586 b07eb8eb0b0c8e7c6c2c133eabe23f49 298 Gene3D G3DSA:3.60.15.10 2 243 2.2E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_0586 b07eb8eb0b0c8e7c6c2c133eabe23f49 298 SMART SM00849 16 210 3.2E-30 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0586 b07eb8eb0b0c8e7c6c2c133eabe23f49 298 Pfam PF00753 Metallo-beta-lactamase superfamily 17 210 1.1E-19 T 14-10-2018 IPR001279 Metallo-beta-lactamase Theos_0586 b07eb8eb0b0c8e7c6c2c133eabe23f49 298 SUPERFAMILY SSF56281 15 259 6.03E-51 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Theos_0336 28f033800a287bde0e866c5896d89021 283 Gene3D G3DSA:3.20.20.70 1 281 1.3E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Theos_0336 28f033800a287bde0e866c5896d89021 283 SUPERFAMILY SSF51569 8 277 6.23E-45 T 14-10-2018 Theos_0336 28f033800a287bde0e866c5896d89021 283 Pfam PF00682 HMGL-like 8 271 3.4E-24 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Theos_0513 911d86b1e4ffffdd7521631bd30edbaf 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 306 5.7E-48 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_1871 771b76acb55e47d313d9feb692204259 201 SUPERFAMILY SSF46785 13 114 5.17E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_2216 84849c2a7d54f12ebaff604d76d8869e 287 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 274 7.3E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_1842 b8e7c401a5d5feb884f40b5ae476a291 63 Pfam PF11127 Protein of unknown function (DUF2892) 1 62 8.7E-21 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 Theos_1979 b33b6d5515df7b4c983ecd120e8e4c35 66 Gene3D G3DSA:1.20.58.1350 1 66 2.0E-31 T 14-10-2018 IPR038405 Cytochrome oxidase Caa3-type, subunit IV superfamily Theos_1909 b9aa93f6bc306603dcd16f297f9a9b26 292 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 58 286 1.0E-90 T 14-10-2018 IPR010787 Protein of unknown function DUF1385 Theos_1909 b9aa93f6bc306603dcd16f297f9a9b26 292 Pfam PF07136 Protein of unknown function (DUF1385) 58 286 6.2E-74 T 14-10-2018 IPR010787 Protein of unknown function DUF1385 Theos_2053 22a56ff3bb5ef00953f85a20bab5e628 199 Pfam PF07849 Protein of unknown function (DUF1641) 140 176 8.9E-15 T 14-10-2018 IPR012440 Protein of unknown function DUF1641 Theos_1611 a3d86830641672b7663ae6d671cff983 221 Pfam PF03379 CcmB protein 6 213 4.4E-37 T 14-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 Theos_1611 a3d86830641672b7663ae6d671cff983 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 54 71 2.4E-14 T 14-10-2018 Theos_1611 a3d86830641672b7663ae6d671cff983 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 157 176 2.4E-14 T 14-10-2018 Theos_1611 a3d86830641672b7663ae6d671cff983 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 28 49 2.4E-14 T 14-10-2018 Theos_1611 a3d86830641672b7663ae6d671cff983 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 77 100 2.4E-14 T 14-10-2018 Theos_1611 a3d86830641672b7663ae6d671cff983 221 PIRSF PIRSF002764 1 219 5.2E-37 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria Theos_1267 38a4364490a4273e565faa5d8151de64 128 SUPERFAMILY SSF54427 2 126 2.6E-22 T 14-10-2018 IPR032710 NTF2-like domain superfamily Theos_1267 38a4364490a4273e565faa5d8151de64 128 Pfam PF08332 Calcium/calmodulin dependent protein kinase II association domain 4 128 3.6E-47 T 14-10-2018 IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain GO:0004683|GO:0005516|GO:0006468 Reactome: R-HSA-3371571|Reactome: R-HSA-399719|Reactome: R-HSA-438066|Reactome: R-HSA-442729|Reactome: R-HSA-442742|Reactome: R-HSA-442982|Reactome: R-HSA-5576892|Reactome: R-HSA-5578775|Reactome: R-HSA-5673001|Reactome: R-HSA-877300|Reactome: R-HSA-936837 Theos_1267 38a4364490a4273e565faa5d8151de64 128 Gene3D G3DSA:3.10.450.50 1 128 3.8E-26 T 14-10-2018 Theos_1031 f2bc54dce6e708a72452eef4543190ff 144 Gene3D G3DSA:1.20.210.10 35 129 2.1E-5 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0512 26aea0987766886e396b8a9df2a2c29b 439 Pfam PF02653 Branched-chain amino acid transport system / permease component 109 419 9.6E-48 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_0794 d6c75e2e0cf13f59972c01203faa738e 88 Pfam PF00708 Acylphosphatase 6 85 4.3E-29 T 14-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Theos_0794 d6c75e2e0cf13f59972c01203faa738e 88 SUPERFAMILY SSF54975 2 87 5.01E-29 T 14-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Theos_0794 d6c75e2e0cf13f59972c01203faa738e 88 Gene3D G3DSA:3.30.70.100 1 88 7.6E-36 T 14-10-2018 Theos_1827 22e525a2fb74fc6aef15d985dcc301db 78 Gene3D G3DSA:2.30.30.320 2 76 1.7E-28 T 14-10-2018 IPR037135 DUF1653-like domain superfamily Theos_1827 22e525a2fb74fc6aef15d985dcc301db 78 Pfam PF07866 Protein of unknown function (DUF1653) 7 67 1.6E-27 T 14-10-2018 IPR023387 DUF1653-like domain Theos_0582 0c2a4ebd0051176678f6ca2f56c9731e 149 Pfam PF03350 Uncharacterized protein family, UPF0114 14 118 3.2E-22 T 14-10-2018 IPR005134 Uncharacterised protein family UPF0114 Theos_1547 5d09b8edbc791867f19a6ddf67e8bb13 290 Pfam PF00535 Glycosyl transferase family 2 6 107 4.1E-27 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Theos_1547 5d09b8edbc791867f19a6ddf67e8bb13 290 Gene3D G3DSA:3.90.550.10 2 218 5.6E-34 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1547 5d09b8edbc791867f19a6ddf67e8bb13 290 SUPERFAMILY SSF53448 4 242 1.04E-40 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Theos_1266 6448881d9bb7eba3afd3fdabea97d84e 514 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 11 512 1.2E-231 T 14-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Theos_1266 6448881d9bb7eba3afd3fdabea97d84e 514 Gene3D G3DSA:3.20.20.240 6 514 1.2E-236 T 14-10-2018 Theos_1266 6448881d9bb7eba3afd3fdabea97d84e 514 Pfam PF01642 Methylmalonyl-CoA mutase 10 508 5.6E-219 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Theos_1266 6448881d9bb7eba3afd3fdabea97d84e 514 SUPERFAMILY SSF51703 12 510 1.96E-209 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Theos_1665 205b94eb406f2896856e395a50d9b18c 318 Pfam PF12679 ABC-2 family transporter protein 12 315 1.2E-35 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 Theos_2398 5a4785af7fe991554e9d13e7ca7443a6 459 Pfam PF10134 Replication initiator protein A 22 256 3.1E-50 T 14-10-2018 IPR018777 Replication initiator protein A Theos_0614 e913eda77b9707a8d9b6621f8e8f3f95 374 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 26 232 3.4E-43 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 Theos_0614 e913eda77b9707a8d9b6621f8e8f3f95 374 SUPERFAMILY SSF53822 32 234 4.04E-10 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Theos_0773 f2641c1750bdc9245cd735a3bf55cb58 103 Gene3D G3DSA:3.40.1350.90 1 103 1.6E-47 T 14-10-2018 Theos_0773 f2641c1750bdc9245cd735a3bf55cb58 103 Pfam PF11572 Protein of unknown function (DUF3234) 7 97 8.6E-37 T 14-10-2018 IPR021628 Protein of unknown function DUF3234 Theos_2058 71871b515e31e6f14f5053113d1b2d86 448 Pfam PF03916 Polysulphide reductase, NrfD 69 389 1.5E-24 T 14-10-2018 IPR005614 NrfD family Theos_0438 70be6a360aaba756a5be511855d928f7 208 Gene3D G3DSA:3.30.70.2830 94 207 2.4E-44 T 14-10-2018 Theos_1588 db701853f4ed134ea2499feb1feb78b9 74 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 71 19.176 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Theos_1588 db701853f4ed134ea2499feb1feb78b9 74 Pfam PF02416 mttA/Hcf106 family 3 52 8.3E-22 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 Theos_1588 db701853f4ed134ea2499feb1feb78b9 74 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 4.1E-21 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Theos_2522 0c16b9e56190b968d5783cde1a26661f 150 Gene3D G3DSA:1.10.1660.10 4 139 1.8E-7 T 14-10-2018 Theos_2522 0c16b9e56190b968d5783cde1a26661f 150 SUPERFAMILY SSF46955 10 123 2.79E-5 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Theos_0484 393a9105d0110b2754f339825c89b7b1 215 Pfam PF04367 Protein of unknown function (DUF502) 61 164 4.4E-26 T 14-10-2018 IPR007462 Protein of unknown function DUF502 Theos_1854 2ba3e2a657cd8f087d6bc43cac19fc0c 123 SUPERFAMILY SSF81301 13 121 1.01E-15 T 14-10-2018 Theos_1854 2ba3e2a657cd8f087d6bc43cac19fc0c 123 Pfam PF01909 Nucleotidyltransferase domain 39 66 4.2E-6 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Theos_1854 2ba3e2a657cd8f087d6bc43cac19fc0c 123 Gene3D G3DSA:3.30.460.10 14 109 2.2E-9 T 14-10-2018 Theos_2385 8783464a5b5a8c167c9a3418d59f2a63 232 Gene3D G3DSA:1.40.20.10 4 230 2.3E-30 T 14-10-2018 IPR038186 CHAD domain superfamily Theos_2385 8783464a5b5a8c167c9a3418d59f2a63 232 SMART SM00880 3 226 5.2E-25 T 14-10-2018 IPR007899 CHAD domain Theos_2385 8783464a5b5a8c167c9a3418d59f2a63 232 Pfam PF05235 CHAD domain 8 191 9.0E-32 T 14-10-2018 IPR007899 CHAD domain Theos_0895 e1262522c20619e033401e195652cc88 178 Gene3D G3DSA:3.40.50.1010 7 169 1.5E-45 T 14-10-2018 Theos_0895 e1262522c20619e033401e195652cc88 178 Pfam PF01936 NYN domain 13 165 1.8E-34 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type Theos_1901 32521f995597efb2487049e999d74962 107 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 18 68 3.2E-9 T 14-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis Theos_1901 32521f995597efb2487049e999d74962 107 SUPERFAMILY SSF53146 1 75 1.44E-15 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Theos_1901 32521f995597efb2487049e999d74962 107 Gene3D G3DSA:3.30.420.130 1 76 1.5E-12 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Theos_2515 25ea86951d287a6a1bbf4361b2df4f79 229 Gene3D G3DSA:1.20.5.340 154 226 2.2E-5 T 14-10-2018 Theos_2515 25ea86951d287a6a1bbf4361b2df4f79 229 SUPERFAMILY SSF57997 108 221 7.85E-6 T 14-10-2018 Theos_0117 397df33627c783fc7630571a9004d6dd 92 Pfam PF07978 NIPSNAP 3 89 1.1E-5 T 14-10-2018 IPR012577 NIPSNAP Theos_0117 397df33627c783fc7630571a9004d6dd 92 SUPERFAMILY SSF54909 1 89 5.37E-7 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Theos_1574 10ba1211acc3eb804d78eee38fc391b3 130 Gene3D G3DSA:3.30.1050.10 1 130 6.2E-42 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily Theos_1574 10ba1211acc3eb804d78eee38fc391b3 130 Pfam PF02036 SCP-2 sterol transfer family 11 105 1.3E-10 T 14-10-2018 IPR003033 SCP2 sterol-binding domain Theos_1574 10ba1211acc3eb804d78eee38fc391b3 130 SUPERFAMILY SSF55718 1 129 1.46E-31 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily Theos_1239 375b834b658a341b30739d5716bce8f9 562 Pfam PF14341 PilX N-terminal 5 54 3.2E-6 T 14-10-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain Theos_1130 05f6dd947d5197b96cfbb439972c6d09 196 Pfam PF08478 POTRA domain, FtsQ-type 26 93 1.3E-11 T 14-10-2018 IPR013685 POTRA domain, FtsQ-type Theos_2256 b57d85849195391cd075e1c4c41e76dc 359 Pfam PF01609 Transposase DDE domain 155 295 1.2E-7 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Theos_2256 b57d85849195391cd075e1c4c41e76dc 359 SUPERFAMILY SSF53098 19 339 2.2E-19 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Theos_0736 3a1615ad7401797ed3dc897179bad959 318 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 14 313 1.8E-107 T 14-10-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily Theos_2074 e744ba4f953c9e3cc611d8c84555e954 73 PIRSF PIRSF002599 1 73 1.1E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 Theos_2074 e744ba4f953c9e3cc611d8c84555e954 73 Pfam PF00313 'Cold-shock' DNA-binding domain 3 67 8.5E-27 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Theos_2074 e744ba4f953c9e3cc611d8c84555e954 73 Gene3D G3DSA:2.40.50.140 1 73 1.0E-32 T 14-10-2018 Theos_2074 e744ba4f953c9e3cc611d8c84555e954 73 SUPERFAMILY SSF50249 1 69 1.71E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Theos_2074 e744ba4f953c9e3cc611d8c84555e954 73 SMART SM00357 3 68 1.1E-29 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 Theos_2074 e744ba4f953c9e3cc611d8c84555e954 73 PRINTS PR00050 Cold shock protein signature 24 33 3.9E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Theos_2074 e744ba4f953c9e3cc611d8c84555e954 73 PRINTS PR00050 Cold shock protein signature 4 19 3.9E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Theos_2074 e744ba4f953c9e3cc611d8c84555e954 73 PRINTS PR00050 Cold shock protein signature 39 57 3.9E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Theos_2074 e744ba4f953c9e3cc611d8c84555e954 73 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 14-10-2018 IPR019844 Cold-shock conserved site Theos_0101 93c82a2db45dbd3e39dfb3bf8c26ad4e 380 Pfam PF12704 MacB-like periplasmic core domain 18 225 4.0E-19 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Theos_0101 93c82a2db45dbd3e39dfb3bf8c26ad4e 380 Pfam PF02687 FtsX-like permease family 281 370 4.8E-11 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Theos_1978 e6972d7a9774bab5211ac0f6d6c1869a 219 Pfam PF04012 PspA/IM30 family 3 218 9.4E-49 T 14-10-2018 IPR007157 PspA/IM30 Theos_0201 e0c87d43c2d30215e9a14f420ce2978e 411 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 4 393 2.4E-108 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 Theos_0201 e0c87d43c2d30215e9a14f420ce2978e 411 Pfam PF00860 Permease family 5 360 3.3E-90 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 Theos_2113 b7fa9665dc76b2b1902a103656edab92 262 Gene3D G3DSA:3.90.226.10 1 205 2.9E-67 T 14-10-2018 Theos_2113 b7fa9665dc76b2b1902a103656edab92 262 SUPERFAMILY SSF52096 17 261 4.56E-61 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_2113 b7fa9665dc76b2b1902a103656edab92 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 261 1.4E-37 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Theos_2113 b7fa9665dc76b2b1902a103656edab92 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Theos_2113 b7fa9665dc76b2b1902a103656edab92 262 Gene3D G3DSA:1.10.12.10 206 262 2.9E-28 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Theos_1939 3e2113e3df307a866f13e9bd90824742 65 SUPERFAMILY SSF54786 4 64 2.43E-10 T 14-10-2018 Theos_1939 3e2113e3df307a866f13e9bd90824742 65 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 6 57 7.1E-7 T 14-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Theos_1939 3e2113e3df307a866f13e9bd90824742 65 Gene3D G3DSA:3.30.920.30 1 65 6.8E-17 T 14-10-2018 IPR038570 HicA superfamily Theos_0127 7bc9eab427dcc66ec407fd2a304b004d 84 Gene3D G3DSA:3.30.160.250 1 84 2.0E-37 T 14-10-2018 Theos_0127 7bc9eab427dcc66ec407fd2a304b004d 84 SUPERFAMILY SSF143100 3 75 1.44E-17 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like Theos_0379 705097160c7b1496b07ce09ad8fcf1bb 250 Pfam PF01578 Cytochrome C assembly protein 83 241 5.7E-16 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 Theos_2170 e467bc8f28af7594134f5d7ec18fd346 119 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 8 111 2.3E-23 T 14-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV Theos_2138 f7b5249b2f708d0fa46dd1f0d68fc69b 497 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 486 4.0E-107 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Theos_1627 ade0127797a69ace9acce0ec9711b364 148 SUPERFAMILY SSF46626 19 126 1.38E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_1627 ade0127797a69ace9acce0ec9711b364 148 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 18 104 2.2E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1627 ade0127797a69ace9acce0ec9711b364 148 Gene3D G3DSA:1.10.760.10 18 148 2.0E-51 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Theos_0200 81f3408ec7fc2a5618edf9ff7383d991 365 Pfam PF01594 AI-2E family transporter 16 355 4.6E-60 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like Theos_2422 5d5258a6d9e1dfd8f9b93e784738017f 210 Pfam PF14332 Domain of unknown function (DUF4388) 5 106 2.0E-7 T 14-10-2018 IPR025497 Domain of unknown function DUF4388 Theos_2239 f0d70f7499ac1801bd02ae3cfc8c8d21 149 Pfam PF10722 Putative bacterial sensory transduction regulator 25 146 1.9E-19 T 14-10-2018 IPR019660 Putative sensory transduction regulator YbjN Theos_2130 ff16e2e5644bb85bcb185d5ac30396e3 270 Pfam PF00892 EamA-like transporter family 138 268 4.3E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_2130 ff16e2e5644bb85bcb185d5ac30396e3 270 Pfam PF00892 EamA-like transporter family 4 126 1.5E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Theos_2130 ff16e2e5644bb85bcb185d5ac30396e3 270 SUPERFAMILY SSF103481 33 129 3.4E-9 T 14-10-2018 Theos_2130 ff16e2e5644bb85bcb185d5ac30396e3 270 SUPERFAMILY SSF103481 176 268 9.02E-14 T 14-10-2018 Theos_1727 20e217b7103864b96e47cc7a57e1d648 105 Pfam PF07883 Cupin domain 33 100 4.8E-18 T 14-10-2018 IPR013096 Cupin 2, conserved barrel Theos_1727 20e217b7103864b96e47cc7a57e1d648 105 Gene3D G3DSA:2.60.120.10 1 105 8.1E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Theos_1727 20e217b7103864b96e47cc7a57e1d648 105 SUPERFAMILY SSF51182 25 103 1.34E-18 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Theos_0347 4f4b50b0bf01ce0aec5777d311dc67c4 397 Gene3D G3DSA:1.20.1250.20 2 385 7.4E-35 T 14-10-2018 Theos_0347 4f4b50b0bf01ce0aec5777d311dc67c4 397 SUPERFAMILY SSF103473 5 388 1.44E-43 T 14-10-2018 IPR036259 MFS transporter superfamily Theos_0347 4f4b50b0bf01ce0aec5777d311dc67c4 397 Pfam PF05977 Transmembrane secretion effector 4 384 4.2E-30 T 14-10-2018 IPR010290 Transmembrane secretion effector Theos_1499 9e6c2e3aa94eac8c5cfd84c046caf21d 562 SUPERFAMILY SSF81442 15 557 3.27E-118 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1499 9e6c2e3aa94eac8c5cfd84c046caf21d 562 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 229 283 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1499 9e6c2e3aa94eac8c5cfd84c046caf21d 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 129 141 6.1E-15 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1499 9e6c2e3aa94eac8c5cfd84c046caf21d 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 298 319 6.1E-15 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1499 9e6c2e3aa94eac8c5cfd84c046caf21d 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 248 6.1E-15 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1499 9e6c2e3aa94eac8c5cfd84c046caf21d 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 429 450 6.1E-15 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1499 9e6c2e3aa94eac8c5cfd84c046caf21d 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 10 35 6.1E-15 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1499 9e6c2e3aa94eac8c5cfd84c046caf21d 562 Gene3D G3DSA:1.20.210.10 2 562 4.7E-164 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_1499 9e6c2e3aa94eac8c5cfd84c046caf21d 562 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 20 468 3.8E-85 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Theos_0826 05f310ece8bdbab8985768a05e343857 461 Pfam PF09670 CRISPR-associated protein (Cas_Cas02710) 68 448 6.8E-72 T 14-10-2018 Theos_0826 05f310ece8bdbab8985768a05e343857 461 SUPERFAMILY SSF52980 58 239 6.97E-6 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Theos_0826 05f310ece8bdbab8985768a05e343857 461 TIGRFAM TIGR02710 TIGR02710: CRISPR-associated protein, TIGR02710 family 81 445 3.1E-26 T 14-10-2018 IPR014082 CRISPR-associated protein, Cas02710 Theos_1899 e96c1f188df1020dd1104be1fa850094 198 ProSitePatterns PS00530 Ribonuclease T2 family histidine active site 1. 162 169 - T 14-10-2018 IPR018188 Ribonuclease T2, His active site 1 GO:0003723|GO:0033897 Reactome: R-HSA-6798695 Theos_1899 e96c1f188df1020dd1104be1fa850094 198 Pfam PF03458 UPF0126 domain 90 165 7.2E-19 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 Theos_1899 e96c1f188df1020dd1104be1fa850094 198 Pfam PF03458 UPF0126 domain 5 76 2.9E-18 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 Theos_2363 ab66cb8eee08705d38ac5880013ca5c4 207 Pfam PF11866 Protein of unknown function (DUF3386) 8 187 5.3E-19 T 14-10-2018 IPR021809 Protein of unknown function DUF3386 Theos_1860 4aea18452336857e8eef2b3f6c59634c 233 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 6 165 2.4E-10 T 14-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain Theos_0932 6676dad41a59da60c95c3d1078a06ac2 166 Gene3D G3DSA:1.10.520.40 2 156 7.7E-55 T 14-10-2018 IPR038287 Cse2 superfamily Theos_0932 6676dad41a59da60c95c3d1078a06ac2 166 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 24 154 1.1E-27 T 14-10-2018 IPR013382 CRISPR-associated protein Cse2 Theos_0932 6676dad41a59da60c95c3d1078a06ac2 166 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 12 155 6.9E-32 T 14-10-2018 IPR013382 CRISPR-associated protein Cse2 Theos_0678 d4018ca38c9bfda8f44dc134123ab448 146 Pfam PF06271 RDD family 2 124 7.9E-28 T 14-10-2018 IPR010432 RDD Theos_1458 ed77e58c0d050aa2eb2b9ac77ba57df5 221 Pfam PF14344 Domain of unknown function (DUF4397) 122 210 7.1E-19 T 14-10-2018 IPR025510 Domain of unknown function DUF4397 Theos_1458 ed77e58c0d050aa2eb2b9ac77ba57df5 221 Pfam PF14344 Domain of unknown function (DUF4397) 22 138 2.2E-30 T 14-10-2018 IPR025510 Domain of unknown function DUF4397 Theos_2116 74b96760d5cadf02224ad1b8941fcd91 113 Pfam PF03780 Asp23 family, cell envelope-related function 3 110 3.4E-27 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 Theos_2268 a9879ce6b3ab016bd64952950efba647 746 Gene3D G3DSA:3.40.50.300 386 478 5.0E-6 T 14-10-2018 Theos_2268 a9879ce6b3ab016bd64952950efba647 746 SUPERFAMILY SSF52540 202 479 3.61E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0557 d6b156dff9f56ca178402ecefbcc6d36 248 Pfam PF01925 Sulfite exporter TauE/SafE 6 241 1.6E-47 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Theos_0067 fc35b67cd028250986c919019b89ea90 470 Pfam PF04434 SWIM zinc finger 55 86 4.9E-6 T 14-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 Theos_0331 0035240765f55836babc307769143f40 88 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 58 87 0.0027 T 14-10-2018 Theos_1211 6c2d4993ac6831cd9104ebabdf798d35 146 Pfam PF04238 Protein of unknown function (DUF420) 8 134 1.3E-36 T 14-10-2018 IPR007352 Protein of unknown function DUF420 Theos_0144 04fb0ec020549b103bd0640b848cd84f 71 Pfam PF11146 Protein of unknown function (DUF2905) 4 68 6.6E-22 T 14-10-2018 IPR021320 Protein of unknown function DUF2905 Theos_2460 0a335c3923da47e3855fcaf44fb1eb19 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 277 5.6E-43 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_1351 3302602d9601f49e645c8a108f2c709a 94 Gene3D G3DSA:3.40.250.10 1 93 1.3E-18 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_1351 3302602d9601f49e645c8a108f2c709a 94 SUPERFAMILY SSF52821 2 92 6.02E-14 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Theos_2338 e772e808d4f4003b1c6c693bae674421 126 SUPERFAMILY SSF54523 11 113 2.35E-6 T 14-10-2018 Theos_2338 e772e808d4f4003b1c6c693bae674421 126 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 28 7.1E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Theos_2217 e1fc5ff08491c765dc4926c9ba52d532 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 293 6.6E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_1566 22725b76833c5b0b57a1514c6c134a85 300 Pfam PF13224 Domain of unknown function (DUF4032) 198 274 7.5E-5 T 14-10-2018 IPR025111 Domain of unknown function DUF4032 Theos_1566 22725b76833c5b0b57a1514c6c134a85 300 SUPERFAMILY SSF110849 48 137 1.15E-7 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Theos_1140 0db10235863bdf2a799d07f19311c08f 403 Pfam PF04143 Sulphur transport 48 373 5.0E-63 T 14-10-2018 IPR007272 Sulphur transport domain Theos_0697 4d81e96cf11f4f7604679841bdacd75a 276 Gene3D G3DSA:3.90.226.10 53 235 3.5E-24 T 14-10-2018 Theos_0697 4d81e96cf11f4f7604679841bdacd75a 276 SUPERFAMILY SSF52096 53 235 2.71E-27 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Theos_0697 4d81e96cf11f4f7604679841bdacd75a 276 Pfam PF01972 Serine dehydrogenase proteinase 6 270 7.0E-128 T 14-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 Theos_0584 d04f4dd230ad2e897646a4cf213fc202 176 Pfam PF02660 Glycerol-3-phosphate acyltransferase 6 144 8.7E-18 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_0584 d04f4dd230ad2e897646a4cf213fc202 176 SMART SM01207 5 169 2.7E-14 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Theos_2315 6d4c6845abb4a97a14a47c056ecc3ad6 219 Pfam PF03824 High-affinity nickel-transport protein 2 54 9.4E-7 T 14-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 Theos_0648 7cac3689b7b9f4f7cc21a6b9af1ff038 316 Gene3D G3DSA:2.120.10.30 1 168 3.2E-7 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Theos_0648 7cac3689b7b9f4f7cc21a6b9af1ff038 316 SUPERFAMILY SSF101898 14 311 1.41E-19 T 14-10-2018 Theos_0319 2fb205bc4e509537ef80e61e02843d22 437 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 251 428 4.8E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Theos_0319 2fb205bc4e509537ef80e61e02843d22 437 SUPERFAMILY SSF161098 204 436 9.68E-54 T 14-10-2018 IPR035906 MetI-like superfamily Theos_1225 381ee6e7aec3da50822f396cc0fbb87d 258 Pfam PF06182 ABC-2 family transporter protein 59 257 2.2E-19 T 14-10-2018 IPR010390 Protein of unknown function DUF990 Theos_0864 932f48a89efe988a78ab3a1495d25e8b 284 Gene3D G3DSA:3.30.70.3040 58 144 1.1E-8 T 14-10-2018 Theos_0864 932f48a89efe988a78ab3a1495d25e8b 284 PIRSF PIRSF003097 1 283 9.4E-55 T 14-10-2018 IPR004513 Cell division protein FtsX GO:0016021 Theos_2251 6d44f6d3823562fa47ec109def03b6e4 336 SUPERFAMILY SSF69322 30 331 3.92E-9 T 14-10-2018 Theos_0167 2ef33eb9d3dec5c210965b0e013ed0b3 364 Pfam PF02073 Thermophilic metalloprotease (M29) 8 340 6.6E-65 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Theos_0167 2ef33eb9d3dec5c210965b0e013ed0b3 364 SUPERFAMILY SSF144052 8 358 1.14E-91 T 14-10-2018 Theos_0235 44140be85330d2492441c07120243ee3 278 Gene3D G3DSA:2.60.40.10 20 107 3.2E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold Theos_1576 9afcbf84621fa22bc304ff429b0ea480 136 Gene3D G3DSA:3.40.50.620 1 136 7.7E-49 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Theos_1576 9afcbf84621fa22bc304ff429b0ea480 136 SUPERFAMILY SSF52402 2 134 3.72E-34 T 14-10-2018 Theos_0890 abb0619303aa17949d7270ae3bbcd5ee 210 Pfam PF03591 AzlC protein 10 144 3.3E-39 T 14-10-2018 IPR011606 Branched-chain amino acid transport, permease Theos_2153 1c09b59b76b5f1f31ee1c092e1f95f63 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 1.7E-13 T 14-10-2018 IPR032806 H repeat-associated protein, N-terminal Theos_0455 c658fb956efda5dcc088440aa28f1082 236 Pfam PF02754 Cysteine-rich domain 3 83 5.5E-15 T 14-10-2018 IPR004017 Cysteine-rich domain Theos_0455 c658fb956efda5dcc088440aa28f1082 236 Pfam PF02754 Cysteine-rich domain 129 210 5.6E-12 T 14-10-2018 IPR004017 Cysteine-rich domain Theos_1385 2f7a19de41c8d6263a008714fe9177c7 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 3.2E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Theos_2481 682c266149e8b77467122967bfff9d5d 353 SUPERFAMILY SSF46785 61 100 1.0E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Theos_0654 82ce6f0cdbd39012e16642821a381494 220 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 33 217 4.5E-26 T 14-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Theos_0654 82ce6f0cdbd39012e16642821a381494 220 SUPERFAMILY SSF53167 5 212 1.7E-46 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Theos_0654 82ce6f0cdbd39012e16642821a381494 220 Pfam PF01048 Phosphorylase superfamily 34 218 8.4E-37 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Theos_0654 82ce6f0cdbd39012e16642821a381494 220 Gene3D G3DSA:3.40.50.1580 3 219 1.7E-44 T 14-10-2018 Theos_0058 bc1f2ed2842cfbb2a2a27aeafb13d6f6 158 SUPERFAMILY SSF54909 2 86 4.56E-5 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Theos_1309 30f61afbfc32a1342f9e0757ade30f5a 496 Pfam PF13148 Protein of unknown function (DUF3987) 82 405 5.9E-49 T 14-10-2018 IPR025048 Protein of unknown function DUF3987) Theos_2324 76dab13842d49df63c38a1c810eefd44 120 Pfam PF11483 Protein of unknown function (DUF3209) 1 117 2.1E-29 T 14-10-2018 IPR021577 Protein of unknown function DUF3209 Theos_0812 3bc9b38a98330e352497b56b0e7ad9d7 113 Pfam PF12723 Protein of unknown function (DUF3809) 17 105 3.2E-13 T 14-10-2018 IPR024219 Protein of unknown function DUF3809 Theos_0812 3bc9b38a98330e352497b56b0e7ad9d7 113 Gene3D G3DSA:3.30.530.70 14 112 1.0E-9 T 14-10-2018 Theos_2542 90fa9ee4c1ac7d33b55b1fb310ec9596 114 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 66 106 8.4E-5 T 14-10-2018 IPR022453 Zinc finger, MqsA-type Theos_0166 ae8a6258a5337d21fcca832329e96954 256 Pfam PF12730 ABC-2 family transporter protein 8 188 1.4E-11 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 Theos_0059 f9b1420563d9c627130404d5b1417079 169 Pfam PF16357 Putative PepSY_TM-like 2 165 2.4E-31 T 14-10-2018 IPR032307 Putative PepSY TM-like protein Theos_0874 edc02da19d63ff82c5feb647b54ef9f5 183 Pfam PF02517 CAAX protease self-immunity 87 173 3.4E-17 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 Theos_1195 59b045923a2b61967765ac338003f56e 255 Pfam PF14332 Domain of unknown function (DUF4388) 2 103 6.0E-13 T 14-10-2018 IPR025497 Domain of unknown function DUF4388 Theos_1190 bc51d752cc9b6f98cc5a503de0dd076a 492 PIRSF PIRSF006247 10 489 7.1E-162 T 14-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 Theos_1190 bc51d752cc9b6f98cc5a503de0dd076a 492 Pfam PF02386 Cation transport protein 101 483 1.9E-57 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 Theos_0675 676588f4d7a0a36a5c637ca1a26eb423 178 Pfam PF02620 Uncharacterized ACR, COG1399 60 174 2.1E-27 T 14-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD Theos_0954 acbb6f18daee4739ca71ed724f77aada 342 Pfam PF00487 Fatty acid desaturase 52 293 3.1E-38 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 Theos_0073 2c36b29e6eb192b3522f5430aff9234d 248 Pfam PF02535 ZIP Zinc transporter 101 238 8.8E-14 T 14-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 Theos_1149 a8d99e24aac9eb47ef3a5dd4754fa335 233 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 129 219 4.4E-21 T 14-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 Theos_1149 a8d99e24aac9eb47ef3a5dd4754fa335 233 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 1 88 1.6E-24 T 14-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 Theos_0031 095dfa00802f0f0f2e978dd8c5bb0735 362 Pfam PF01882 Protein of unknown function DUF58 157 235 2.2E-11 T 14-10-2018 IPR002881 Domain of unknown function DUF58 Theos_0495 bc59cdda9914b09a27dc9a90f65435e3 279 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 2 181 4.7E-7 T 14-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 Theos_1102 7875dcd3f4bde01da7a9e910c8f7e567 124 SUPERFAMILY SSF159888 21 88 6.67E-10 T 14-10-2018 Theos_2252 1b86b68248e79eef378341718058629e 449 Gene3D G3DSA:2.60.220.30 37 164 4.3E-7 T 14-10-2018 Theos_2093 953698d688afeb223b2f846654c249b6 115 Pfam PF11255 Protein of unknown function (DUF3054) 5 108 6.6E-15 T 14-10-2018 IPR021414 Protein of unknown function DUF3054 Theos_1223 a5e7aee11759d4c0c40428be92df7fca 258 Pfam PF06182 ABC-2 family transporter protein 35 257 2.6E-63 T 14-10-2018 IPR010390 Protein of unknown function DUF990 Theos_0651 ffac954eeed11cae162f4e9ea6f56a3e 95 Pfam PF08734 GYD domain 4 91 1.9E-27 T 14-10-2018 IPR014845 Protein GYD/TTHA1554 Theos_1983 f7d63e88c5bc9454bc198a5b75c32f5a 255 Pfam PF04468 PSP1 C-terminal conserved region 53 136 1.7E-13 T 14-10-2018 IPR007557 PSP1, C-terminal Theos_0460 38887f05b161e71831110a1f5dfbc56f 369 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 368 9.3E-52 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Theos_1034 59b3f8e05cfce77f36d11dc4dc9203e9 72 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 2 71 4.0E-35 T 14-10-2018 IPR018720 Domain of unknown function DUF2249 Theos_0556 6838c7e0352d3abfd48ca1f41bd90457 109 Pfam PF03779 SPW repeat 6 48 2.0E-16 T 14-10-2018 IPR005530 SPW repeat Theos_0556 6838c7e0352d3abfd48ca1f41bd90457 109 Pfam PF03779 SPW repeat 58 102 4.2E-19 T 14-10-2018 IPR005530 SPW repeat Theos_0892 091cb1f615e65ade4d80b55a68186590 349 SUPERFAMILY SSF117074 192 290 2.48E-6 T 14-10-2018 Theos_0892 091cb1f615e65ade4d80b55a68186590 349 Gene3D G3DSA:2.60.40.10 196 301 2.6E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold Theos_0124 90e2ff4abd38eb46c8c6cab4d3df9e24 233 Gene3D G3DSA:3.40.50.300 18 186 2.8E-9 T 14-10-2018 Theos_0124 90e2ff4abd38eb46c8c6cab4d3df9e24 233 SUPERFAMILY SSF52540 19 156 4.39E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Theos_0340 a73df9a8a38dcc5ba9d1d4d4e66a83dd 88 Pfam PF11950 Protein of unknown function (DUF3467) 5 79 8.8E-18 T 14-10-2018 IPR021857 Protein of unknown function DUF3467