locus-tag	class	description
TSC_c00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TSC_c00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TSC_c00030	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TSC_c00090	ENOG4108ZF3	Phosphatase
TSC_c00100	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TSC_c00120	ENOG4105KRF	dihydroneopterin aldolase
TSC_c00130	ENOG4105EEI	dihydropteroate synthase
TSC_c00170	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TSC_c00180	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TSC_c00210	ENOG41067HZ	cytochrome C, class I
TSC_c00240	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TSC_c00250	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TSC_c00270	ENOG41087YS	Phage shock protein A
TSC_c00290	ENOG4105CJ1	ABC, transporter
TSC_c00300	ENOG4107QWP	ABC-2 type transporter
TSC_c00330	ENOG4105C6T	cysteine synthase
TSC_c00340	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TSC_c00360	ENOG4105VEQ	Cold shock protein
TSC_c00370	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TSC_c00400	ENOG4107ZT3	family UPF0126
TSC_c00410	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TSC_c00500	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TSC_c00590	ENOG4105CJ1	ABC, transporter
TSC_c00640	ENOG4105DXN	mazG family
TSC_c00660	ENOG4107R7Y	intracellular protease Pfpi family
TSC_c00670	ENOG4107RRU	Involved in both the arginine and lysine biosynthetic pathways (By similarity)
TSC_c00690	ENOG4105C6E	dna polymerase iii
TSC_c00720	ENOG4105VPX	protein, conserved in bacteria
TSC_c00740	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
TSC_c00750	ENOG4105DQU	oxidoreductase, subunit beta
TSC_c00790	ENOG4105C0B	DNA polymerase III (alpha subunit)
TSC_c00810	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TSC_c00820	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TSC_c00840	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TSC_c00870	ENOG4108RWN	rrna methyltransferase
TSC_c00890	ENOG4105C89	phosphohexose isomerase
TSC_c00900	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
TSC_c00910	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
TSC_c00930	ENOG4105BZ9	Cytochrome C oxidase, subunit I
TSC_c00990	ENOG4105BZ9	Cytochrome C oxidase, subunit I
TSC_c01000	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
TSC_c01050	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TSC_c01070	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TSC_c01080	ENOG4105E2Z	phosphate ABC transporter (Permease
TSC_c01090	ENOG4105C8U	phosphate abc transporter
TSC_c01110	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TSC_c01150	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
TSC_c01160	ENOG4105G5W	regulator Fur family
TSC_c01190	ENOG4108KB2	LysR family Transcriptional regulator
TSC_c01200	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
TSC_c01210	ENOG4107QSN	dihydrolipoamide acetyltransferase
TSC_c01220	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TSC_c01240	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TSC_c01250	ENOG4105CHM	Aminotransferase
TSC_c01260	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
TSC_c01290	ENOG4105F4P	)-transporter
TSC_c01300	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TSC_c01310	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TSC_c01330	ENOG4108J2R	molybdopterin oxidoreductase
TSC_c01340	ENOG4105EBR	Carboxylesterase
TSC_c01350	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TSC_c01370	ENOG4105CH5	extracellular solute-binding protein, family 7
TSC_c01380	ENOG4107T3P	ABC, transporter
TSC_c01410	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
TSC_c01420	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TSC_c01440	ENOG4107RDB	Major Facilitator
TSC_c01460	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TSC_c01470	ENOG41082T9	Membrane
TSC_c01510	ENOG4105CVJ	phosphoglycerate mutase
TSC_c01520	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TSC_c01530	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TSC_c01540	ENOG4105CZX	twitching motility protein
TSC_c01550	ENOG4107QHF	type ii secretion system protein e
TSC_c01560	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
TSC_c01580	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
TSC_c01590	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TSC_c01600	ENOG4105WMR	Protein CrcB homolog
TSC_c01610	ENOG4105KJJ	Uncharacterized ACR, COG1993
TSC_c01640	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
TSC_c01670	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
TSC_c01680	ENOG4105SYT	Methylenetetrahydrofolate reductase
TSC_c01690	ENOG4105CY0	Metallo-Beta-Lactamase
TSC_c01740	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TSC_c01750	ENOG4105WDJ	50S ribosomal protein L33
TSC_c01760	ENOG410683Z	Preprotein translocase SecE subunit
TSC_c01770	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TSC_c01780	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TSC_c01790	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TSC_c01800	ENOG4108VZM	50s ribosomal protein L10
TSC_c01810	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TSC_c01820	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TSC_c01830	ENOG4105C1G	acyl-Coa dehydrogenase
TSC_c01840	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TSC_c01850	ENOG4108JZA	Homocitrate synthase
TSC_c01880	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TSC_c01890	ENOG4108S93	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TSC_c01910	ENOG4106928	lysine biosynthesis protein LysW
TSC_c01920	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
TSC_c01930	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TSC_c01940	ENOG4107U4Q	acetylglutamate kinase
TSC_c01950	ENOG4107RFW	hydrolase family 57
TSC_c01970	ENOG4105C4K	Nad synthetase
TSC_c02000	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TSC_c02020	ENOG4105K4H	Nlp p60 protein
TSC_c02030	ENOG4108DBC	nitroreductase
TSC_c02060	ENOG4105CTD	carboxy-peptidase
TSC_c02070	ENOG4105CBP	Major Facilitator
TSC_c02100	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
TSC_c02130	ENOG4108Z5K	methylglyoxal synthase
TSC_c02140	ENOG4105C0P	Mg chelatase subunit ChlI
TSC_c02180	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TSC_c02190	ENOG4105W8H	transhydrogenase (subunit alpha
TSC_c02200	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TSC_c02220	ENOG41082AW	Binds together with S18 to 16S ribosomal RNA (By similarity)
TSC_c02230	ENOG4105Z8H	single-stranded DNA-binding protein
TSC_c02240	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TSC_c02250	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TSC_c02260	ENOG4105E1F	short-chain dehydrogenase reductase
TSC_c02280	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TSC_c02290	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
TSC_c02350	ENOG4107QN2	dihydrolipoyl dehydrogenase
TSC_c02380	ENOG4105ZVY	2-oxoisovalerate dehydrogenase, E1 component beta subunit
TSC_c02390	ENOG4105CPP	Dehydrogenase, E1 component
TSC_c02400	ENOG4107SUU	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
TSC_c02410	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
TSC_c02440	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
TSC_c02450	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TSC_c02460	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
TSC_c02480	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TSC_c02500	ENOG4105D8X	mechanosensitive ion channel
TSC_c02510	ENOG4107T9V	chlorite dismutase
TSC_c02570	ENOG4105DHQ	Histidine kinase
TSC_c02600	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TSC_c02610	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TSC_c02620	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TSC_c02640	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TSC_c02650	ENOG4108UKI	Enoyl-CoA hydratase
TSC_c02680	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
TSC_c02690	ENOG4105C7S	Dehydrogenase
TSC_c02700	ENOG4107QN2	dihydrolipoyl dehydrogenase
TSC_c02740	ENOG4105CDH	Citrulline--aspartate ligase
TSC_c02750	ENOG4105CH7	arginosuccinase
TSC_c02760	ENOG4105CH7	arginosuccinase
TSC_c02790	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TSC_c02800	ENOG4105CKU	formyltetrahydrofolate synthetase
TSC_c02910	ENOG4105ER6	polysaccharide biosynthesis protein
TSC_c02930	ENOG4108MKI	Glycosyl transferase, family 2
TSC_c02940	ENOG4105CG5	Glycosyl transferase (Group 1
TSC_c02960	ENOG4108KMV	Glycosyl transferase (Group 1
TSC_c02980	ENOG4105D3Q	Sugar transferase
TSC_c03000	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TSC_c03060	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TSC_c03070	ENOG4105K46	50S ribosomal protein l27
TSC_c03080	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TSC_c03090	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TSC_c03120	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
TSC_c03140	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
TSC_c03160	ENOG4105CZX	twitching motility protein
TSC_c03200	ENOG4105DR5	peptidase
TSC_c03220	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
TSC_c03230	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
TSC_c03270	ENOG4108Z4U	Ferredoxin
TSC_c03300	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TSC_c03320	ENOG4105C5R	Aminotransferase
TSC_c03330	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TSC_c03340	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
TSC_c03350	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TSC_c03380	ENOG4107Z3H	Transcriptional regulator, TetR family
TSC_c03440	ENOG4107SFQ	iron-sulfur binding
TSC_c03490	ENOG4105CEP	NADH dehydrogenase
TSC_c03510	ENOG4105BZU	Histidine kinase
TSC_c03520	ENOG4108KB0	deacetylase
TSC_c03550	ENOG4105C8Y	Acetylornithine aminotransferase
TSC_c03560	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TSC_c03570	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TSC_c03580	ENOG4105K63	Thioredoxin
TSC_c03590	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
TSC_c03640	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
TSC_c03650	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TSC_c03670	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TSC_c03690	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
TSC_c03710	ENOG4108UNV	SUF system FeS assembly protein, NifU family
TSC_c03720	ENOG4105C9B	Cysteine desulfurase
TSC_c03740	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
TSC_c03790	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TSC_c03820	ENOG4105BZU	Histidine kinase
TSC_c03830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TSC_c03910	ENOG4105DIW	FeS assembly protein SUFB
TSC_c03920	ENOG4105C3K	feS assembly ATPase SufC
TSC_c03950	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TSC_c03960	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TSC_c03970	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TSC_c04010	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TSC_c04030	ENOG4106B0N	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
TSC_c04090	ENOG4107WEA	mandelate racemase muconate lactonizing
TSC_c04120	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
TSC_c04130	ENOG4105CEV	competence damage-inducible protein
TSC_c04140	ENOG4108784	2'-5' rna ligase
TSC_c04150	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TSC_c04160	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TSC_c04190	ENOG4105DFF	Rod shape-determining protein mreb
TSC_c04200	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TSC_c04230	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TSC_c04240	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TSC_c04250	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
TSC_c04290	ENOG4105D38	putrescine abc transporter
TSC_c04300	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
TSC_c04320	ENOG41090A4	Pterin carbinolamine dehydratase
TSC_c04340	ENOG4105CQB	FAD linked oxidase domain protein
TSC_c04390	ENOG41068WN	
TSC_c04420	ENOG4108IUW	ABC transporter
TSC_c04430	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
TSC_c04450	ENOG4105CPC	Aldo Keto reductase
TSC_c04470	ENOG4105CUJ	penicillin amidase
TSC_c04480	ENOG41080XP	Cbs domain
TSC_c04500	ENOG4105DAN	ATP-dependent protease
TSC_c04510	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TSC_c04530	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TSC_c04540	ENOG4108ZHD	aig2 family
TSC_c04550	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TSC_c04570	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TSC_c04580	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TSC_c04610	ENOG4105EAH	synthase
TSC_c04630	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TSC_c04700	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
TSC_c04750	ENOG4105FDK	ABC transporter
TSC_c04780	ENOG4105C0D	helicase
TSC_c04810	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TSC_c04840	ENOG4105BZU	Histidine kinase
TSC_c04880	ENOG4108W63	CRP FNR family transcriptional regulator
TSC_c04910	ENOG4105VF7	tolerance protein
TSC_c04920	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TSC_c04930	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
TSC_c04940	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TSC_c04950	ENOG4105WH1	Two component transcriptional regulator luxr family
TSC_c04980	ENOG4105BZ1	(ABC) transporter
TSC_c04990	ENOG4105BZ1	(ABC) transporter
TSC_c05000	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TSC_c05020	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TSC_c05030	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TSC_c05040	ENOG4105DEF	Extracellular solute-binding protein, family 5
TSC_c05050	ENOG4108IV0	ABC, transporter
TSC_c05060	ENOG4105C0Z	ABC transporter
TSC_c05070	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
TSC_c05080	ENOG4105C32	Amino acid ABC transporter (Permease)
TSC_c05100	ENOG4105C5F	glutamine synthetase
TSC_c05110	ENOG4105CGH	5'-nucleotidase
TSC_c05130	ENOG41067HZ	cytochrome C, class I
TSC_c05150	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TSC_c05160	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TSC_c05170	ENOG4105CIY	formyltetrahydrofolate deformylase
TSC_c05180	ENOG4105C0H	protease
TSC_c05270	ENOG4107SFI	Major Facilitator superfamily
TSC_c05280	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TSC_c05290	ENOG4105ESV	Glycosyl transferase, family 4
TSC_c05300	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TSC_c05330	ENOG4106YGA	NADH dehydrogenase (quinone)
TSC_c05340	ENOG4108VUY	thioesterase Superfamily protein
TSC_c05350	ENOG4105CSA	Coproporphyrinogen iii oxidase
TSC_c05410	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TSC_c05420	ENOG4105CQB	FAD linked oxidase domain protein
TSC_c05430	ENOG4105CQB	FAD linked oxidase domain protein
TSC_c05440	ENOG4107R9S	Malate synthase
TSC_c05450	ENOG4107HP6	Transcriptional regulator
TSC_c05460	ENOG4105KNI	merR family transcriptional Regulator
TSC_c05470	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TSC_c05480	ENOG4108N5B	2-phosphosulfolactate phosphatase
TSC_c05490	ENOG4105IJJ	transcriptional regulator, crp fnr family
TSC_c05500	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TSC_c05520	ENOG4105E39	Enoyl-CoA hydratase
TSC_c05550	ENOG4105CEY	Amp-dependent synthetase and ligase
TSC_c05560	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TSC_c05570	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TSC_c05620	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TSC_c05640	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TSC_c05650	ENOG4108IUZ	ABC transporter
TSC_c05670	ENOG4105VB6	UPF0109 protein
TSC_c05680	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
TSC_c05690	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TSC_c05700	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TSC_c05710	ENOG4108C4G	50S ribosomal protein L34
TSC_c05720	ENOG4105C0Z	ABC transporter
TSC_c05740	ENOG4105C32	Amino acid ABC transporter (Permease)
TSC_c05750	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
TSC_c05770	ENOG4108IV0	ABC, transporter
TSC_c05780	ENOG4105C34	Pseudouridine synthase
TSC_c05810	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TSC_c05820	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
TSC_c05830	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TSC_c05840	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TSC_c05850	ENOG4105CHR	reductase
TSC_c05860	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TSC_c05870	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TSC_c05880	ENOG41067VY	50S ribosomal protein L32
TSC_c05920	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TSC_c05930	ENOG4107WFQ	NADH-quinone oxidoreductase, chain M
TSC_c05940	ENOG4105D65	subunit l
TSC_c05950	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TSC_c05960	ENOG41087XN	oxidoreductase
TSC_c05970	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TSC_c05980	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TSC_c05990	ENOG4108IEH	NADH dehydrogenase subunit g
TSC_c06000	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
TSC_c06010	ENOG4105GKE	subunit e
TSC_c06020	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TSC_c06030	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TSC_c06040	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TSC_c06050	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TSC_c06060	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TSC_c06080	ENOG4105VIZ	double-strand break repair protein
TSC_c06180	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TSC_c06190	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TSC_c06200	ENOG4107Y7Q	pfkb domain protein
TSC_c06210	ENOG4105DZS	Phenylacetate-CoA ligase
TSC_c06220	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
TSC_c06230	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TSC_c06270	ENOG4107TS3	membrane protein, TerC
TSC_c06290	ENOG4105VG1	fes assembly suf system protein
TSC_c06310	ENOG4105VQU	rdd domain containing protein
TSC_c06320	ENOG4105D07	Signal peptide peptidase, SppA
TSC_c06330	ENOG4105DR4	Methyltransferase
TSC_c06340	ENOG4105BZN	citrate synthase
TSC_c06350	ENOG4105D06	uba thif-type nad fad binding protein
TSC_c06360	ENOG4108UW5	maltose o-acetyltransferase
TSC_c06370	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TSC_c06390	ENOG4105WEF	catalase
TSC_c06400	ENOG4105C5Q	Transcriptional regulator
TSC_c06410	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TSC_c06420	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
TSC_c06430	ENOG4107ZZY	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TSC_c06440	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
TSC_c06460	ENOG4105DHP	deoxycytidine triphosphate deaminase
TSC_c06480	ENOG4105D1H	recombination factor protein RarA
TSC_c06490	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
TSC_c06500	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TSC_c06540	ENOG4105KME	endoribonuclease L-psp
TSC_c06550	ENOG4107QPV	Serine Threonine protein kinase
TSC_c06570	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TSC_c06590	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TSC_c06610	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
TSC_c06620	ENOG4105BZU	Histidine kinase
TSC_c06630	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TSC_c06650	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
TSC_c06720	ENOG4107U9H	DNA polymerase
TSC_c06780	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
TSC_c06790	ENOG4105C9X	ppx gppa phosphatase
TSC_c06810	ENOG4105CPQ	Dehydrogenase
TSC_c06850	ENOG4107R1I	NAD-dependent malic enzyme
TSC_c06880	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TSC_c06890	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TSC_c06900	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TSC_c06910	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TSC_c06940	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TSC_c06950	ENOG4107QY8	reductase
TSC_c06970	ENOG4105WH1	Two component transcriptional regulator luxr family
TSC_c06990	ENOG4105DTN	riboflavin biosynthesis protein ribF
TSC_c07000	ENOG4107VIJ	nudix hydrolase
TSC_c07030	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TSC_c07040	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
TSC_c07050	ENOG4105CFH	Aspartokinase
TSC_c07060	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
TSC_c07070	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TSC_c07080	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TSC_c07090	ENOG4105F8J	Adenylate Guanylate cyclase
TSC_c07110	ENOG4108I5C	dEAD DEAH box helicase
TSC_c07120	ENOG4108ZBR	Gcn5-related n-acetyltransferase
TSC_c07150	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TSC_c07190	ENOG4105BZU	Histidine kinase
TSC_c07210	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TSC_c07220	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
TSC_c07230	ENOG4108YYC	ycei family
TSC_c07240	ENOG4108XHF	Pfam:DUF178
TSC_c07250	ENOG4105DVY	radical SAM domain protein
TSC_c07280	ENOG4105ETE	Transcriptional regulator (LacI family
TSC_c07290	ENOG41071YG	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TSC_c07300	ENOG4105ERH	Fumarylacetoacetate hydrolase
TSC_c07320	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TSC_c07330	ENOG4107QNG	Phosphoribosylglycinamide synthetase
TSC_c07340	ENOG4108IRC	dna polymerase iii
TSC_c07360	ENOG4105JJR	Histidine kinase
TSC_c07410	ENOG4107QN1	sodium solute
TSC_c07430	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TSC_c07440	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TSC_c07450	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TSC_c07490	ENOG4105KVH	Transcriptional regulator
TSC_c07510	ENOG4108CHF	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
TSC_c07520	ENOG4105CNI	cell division protein FtsW
TSC_c07530	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TSC_c07540	ENOG4105F38	ABC transporter, permease
TSC_c07550	ENOG4105D38	putrescine abc transporter
TSC_c07560	ENOG4107RUE	extracellular solute-binding protein family 1
TSC_c07570	ENOG41067HZ	cytochrome C, class I
TSC_c07580	ENOG4105C01	Dihydroxy-acid dehydratase
TSC_c07590	ENOG4105C2D	reductase
TSC_c07620	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TSC_c07630	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TSC_c07650	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TSC_c07680	ENOG4105C31	Tryptophanyl-tRNA synthetase
TSC_c07760	ENOG4105VXP	Protein of unknown function DUF86
TSC_c07790	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TSC_c07800	ENOG4105DFA	alanine racemase domain protein
TSC_c07820	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TSC_c07830	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
TSC_c07850	ENOG4105CPQ	Dehydrogenase
TSC_c07870	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TSC_c07880	ENOG4105MJ2	Competence protein
TSC_c07930	ENOG4105EYH	Exonuclease
TSC_c07970	ENOG4105G6Z	alkaline phosphatase
TSC_c08000	ENOG4105C1V	Peptidase, M16
TSC_c08010	ENOG4105C1V	Peptidase, M16
TSC_c08020	ENOG4107Y9U	Membrane
TSC_c08030	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
TSC_c08040	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
TSC_c08050	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
TSC_c08060	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
TSC_c08070	ENOG4105CTP	PilT protein domain protein
TSC_c08080	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TSC_c08100	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TSC_c08160	ENOG4105DZR	Type I site-specific deoxyribonuclease
TSC_c08220	ENOG4105CVR	type I restriction-modification system
TSC_c08270	ENOG4105CGU	Enoyl-CoA hydratase
TSC_c08280	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TSC_c08290	ENOG410868C	50s ribosomal protein l35
TSC_c08310	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TSC_c08330	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TSC_c08340	ENOG41080X4	futalosine nucleosidase
TSC_c08350	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TSC_c08360	ENOG4105C9Q	fumarate hydratase class II
TSC_c08370	ENOG4105EE5	Membrane protein terC
TSC_c08380	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
TSC_c08390	ENOG4105C7K	acetolactate synthase
TSC_c08400	ENOG4108ZP8	Acetolactate synthase small subunit
TSC_c08410	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
TSC_c08420	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TSC_c08430	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TSC_c08460	ENOG4108IUW	ABC transporter
TSC_c08520	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TSC_c08540	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TSC_c08580	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
TSC_c08610	ENOG4108KGH	TRANSCRIPTIONal
TSC_c08640	ENOG4105CJR	Integral membrane protein (MviN
TSC_c08660	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TSC_c08670	ENOG4108V5V	Serine Threonine protein kinase
TSC_c08680	ENOG4105E8R	UPF0173 metal-dependent hydrolase
TSC_c08710	ENOG4105DR4	Methyltransferase
TSC_c08730	ENOG4105EBX	v-type atpase
TSC_c08760	ENOG41089ID	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TSC_c08770	ENOG410704R	Produces ATP from ADP in the presence of a proton gradient across the membrane
TSC_c08780	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TSC_c08790	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
TSC_c08800	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TSC_c08810	ENOG4107QM5	aconitate hydratase
TSC_c08910	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TSC_c08950	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TSC_c08970	ENOG4105C1G	acyl-Coa dehydrogenase
TSC_c08980	ENOG4105F2C	Acetyl-CoA acetyltransferase
TSC_c09000	ENOG410846T	CoA-transferase family III
TSC_c09020	ENOG4108IV0	ABC, transporter
TSC_c09030	ENOG4105C0Z	ABC transporter
TSC_c09040	ENOG4105C32	Amino acid ABC transporter (Permease)
TSC_c09050	ENOG4105C32	Amino acid ABC transporter (Permease)
TSC_c09070	ENOG4108Z7G	MaoC domain protein dehydratase
TSC_c09090	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
TSC_c09100	ENOG4105CEY	Amp-dependent synthetase and ligase
TSC_c09120	ENOG41061ZR	Transcriptional regulator
TSC_c09130	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TSC_c09150	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TSC_c09170	ENOG4105CHV	Transcription elongation factor NusA
TSC_c09180	ENOG410836C	Required for maturation of 30S ribosomal subunits (By similarity)
TSC_c09190	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TSC_c09200	ENOG4108R6K	riboflavin synthase, subunit alpha
TSC_c09210	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TSC_c09250	ENOG4105D5P	Methylmalonyl-coA mutase
TSC_c09280	ENOG4105CRK	lysyL-tRNA synthetase
TSC_c09290	ENOG4105RTX	GreA GreB family elongation factor
TSC_c09310	ENOG41080IJ	Diacylglycerol kinase
TSC_c09320	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TSC_c09330	ENOG4105C9A	Phoh family
TSC_c09350	ENOG4105DI5	UPF0365 protein
TSC_c09370	ENOG4105E2X	shikimate dehydrogenase
TSC_c09400	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TSC_c09430	ENOG4105C8Y	Acetylornithine aminotransferase
TSC_c09440	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TSC_c09450	ENOG41081CK	Memo-like protein
TSC_c09460	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TSC_c09470	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TSC_c09480	ENOG4105EMU	Dehydrogenase
TSC_c09500	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TSC_c09510	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
TSC_c09530	ENOG4105C0Z	ABC transporter
TSC_c09540	ENOG4108IV0	ABC, transporter
TSC_c09550	ENOG4105C32	Amino acid ABC transporter (Permease)
TSC_c09560	ENOG4105CP9	extracellular ligand-binding receptor
TSC_c09570	ENOG4106IQC	argininosuccinate lyase
TSC_c09580	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
TSC_c09630	ENOG4105CN5	Metallo-Beta-Lactamase
TSC_c09640	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TSC_c09650	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TSC_c09680	ENOG4107RQ2	Cytochrome c oxidase, subunit I
TSC_c09690	ENOG4105NAA	Cytochrome C oxidase, subunit II
TSC_c09700	ENOG4105CXV	gliding motility protein
TSC_c09730	ENOG4105CYW	agmatinase
TSC_c09770	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TSC_c09780	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
TSC_c09790	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TSC_c09810	ENOG41082MB	Involved in the transcription termination process (By similarity)
TSC_c09820	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TSC_c09850	ENOG4105DF6	Fe-S oxidoreductase
TSC_c09870	ENOG4107TS3	membrane protein, TerC
TSC_c09880	ENOG4108SA1	esterase
TSC_c09900	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TSC_c09910	ENOG4105CPK	Glycosyl transferase (Group 1
TSC_c10000	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TSC_c10010	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
TSC_c10030	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TSC_c10040	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TSC_c10070	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
TSC_c10120	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TSC_c10150	ENOG4108P8R	
TSC_c10190	ENOG4105C2J	ABC transporter
TSC_c10200	ENOG4105UIB	(ABC) transporter
TSC_c10230	ENOG4108JPW	Aminotransferase
TSC_c10240	ENOG4108YZ4	nudix hydrolase
TSC_c10260	ENOG4105DC1	bifunctional purine biosynthesis protein purh
TSC_c10280	ENOG410839S	Toxic component of a toxin-antitoxin (TA) module (By similarity)
TSC_c10290	ENOG4105ECK	Fatty Acid Desaturase
TSC_c10300	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
TSC_c10310	ENOG4105EPR	degv family
TSC_c10320	ENOG4105EPR	degv family
TSC_c10370	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TSC_c10380	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TSC_c10420	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TSC_c10440	ENOG4105C26	Dehydrogenase
TSC_c10450	ENOG4105EFA	4-hydroxyphenylacetate
TSC_c10460	ENOG4105MXW	flavin reductase domain protein, FMN-binding
TSC_c10500	ENOG4105C0Z	ABC transporter
TSC_c10510	ENOG4108IV0	ABC, transporter
TSC_c10530	ENOG4105DZS	Phenylacetate-CoA ligase
TSC_c10560	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TSC_c10570	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TSC_c10590	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TSC_c10600	ENOG4105E7W	lamb ycsf family protein
TSC_c10610	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TSC_c10640	ENOG4107UWC	ABC, transporter
TSC_c10650	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
TSC_c10680	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
TSC_c10690	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TSC_c10700	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TSC_c10720	ENOG4107PP3	Acetylornithine deacetylase
TSC_c10740	ENOG41089UC	methyltransferase, type 11
TSC_c10760	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TSC_c10770	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TSC_c10780	ENOG4105CE4	GlcNAc 6-P deacetylase
TSC_c10800	ENOG4105FDP	GntR family transcriptional regulator
TSC_c10820	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
TSC_c10830	ENOG4105D17	glycoside hydrolase, family 3 domain protein
TSC_c10850	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
TSC_c10860	ENOG4105DRS	transport system, permease
TSC_c10870	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
TSC_c10890	ENOG41065SU	Two-component system sensor kinase
TSC_c10900	ENOG4105ETX	regulatoR
TSC_c10940	ENOG4108Z86	Glutamine amidotransferase
TSC_c10970	ENOG4107YZX	Universal stress protein
TSC_c11000	ENOG4105KJJ	Uncharacterized ACR, COG1993
TSC_c11030	ENOG4105C98	muts2 protein
TSC_c11070	ENOG4105GR3	Histidine kinase
TSC_c11090	ENOG41067HZ	cytochrome C, class I
TSC_c11100	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
TSC_c11140	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TSC_c11150	ENOG4108QY0	Membrane
TSC_c11180	ENOG4105C0H	protease
TSC_c11210	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
TSC_c11250	ENOG4107EUI	c reductase, iron-sulfur
TSC_c11350	ENOG4105EET	magnesium chelatase
TSC_c11400	ENOG4108PVQ	transcriptional regulator
TSC_c11470	ENOG4108SBK	dioxygenase, subunit beta
TSC_c11480	ENOG4105FUY	alpha subunit
TSC_c11490	ENOG4105C2J	ABC transporter
TSC_c11580	ENOG41084KP	4-oxalocrotonate tautomerase
TSC_c11630	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TSC_c11670	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TSC_c11690	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TSC_c11700	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TSC_c11720	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TSC_c11730	ENOG4107RIQ	Sulfate adenylate transferase
TSC_c11740	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TSC_c11750	ENOG4107TSN	permease
TSC_c11760	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
TSC_c11770	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TSC_c11780	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
TSC_c11790	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
TSC_c11800	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TSC_c11810	ENOG4108G2S	Thiamine biosynthesis protein thiS
TSC_c11820	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
TSC_c11840	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
TSC_c11850	ENOG4105DWF	phosphomethylpyrimidine kinase
TSC_c11860	ENOG4105CHR	reductase
TSC_c11870	ENOG4105CEY	Amp-dependent synthetase and ligase
TSC_c11890	ENOG4105DXM	phenylacetic acid degradation protein
TSC_c11900	ENOG4105C1G	acyl-Coa dehydrogenase
TSC_c11910	ENOG4108RZE	Tetr family transcriptional regulator
TSC_c11920	ENOG4107NFR	Fructose-1,6-bisphosphatase
TSC_c11950	ENOG4105BZU	Histidine kinase
TSC_c11980	ENOG4105C6F	GntR Family Transcriptional Regulator
TSC_c11990	ENOG4105DEF	Extracellular solute-binding protein, family 5
TSC_c12010	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TSC_c12020	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TSC_c12040	ENOG4105DRS	transport system, permease
TSC_c12050	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
TSC_c12070	ENOG4105ETE	Transcriptional regulator (LacI family
TSC_c12110	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TSC_c12120	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TSC_c12150	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
TSC_c12170	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
TSC_c12190	ENOG4105DXM	phenylacetic acid degradation protein
TSC_c12210	ENOG4108UQY	Iron-storage protein
TSC_c12220	ENOG4108IYU	L-aspartate oxidase
TSC_c12230	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
TSC_c12260	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TSC_c12310	ENOG4105BZU	Histidine kinase
TSC_c12320	ENOG4105DZR	Type I site-specific deoxyribonuclease
TSC_c12380	ENOG4105D5G	Transposase
TSC_c12410	ENOG4105VXP	Protein of unknown function DUF86
TSC_c12440	ENOG4105PWE	CRISPR-associated protein cas2
TSC_c12470	ENOG4108VWQ	crispr-associated protein
TSC_c12480	ENOG41060M0	Crispr-associated protein, cse4 family
TSC_c12650	ENOG4105C26	Dehydrogenase
TSC_c12700	ENOG4105C7Z	Conserved Protein
TSC_c12710	ENOG4105CHU	acetyl-coa acetyltransferase
TSC_c12720	ENOG4105P4J	Allophanate hydrolase, subunit 1
TSC_c12730	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TSC_c12750	ENOG4105CSU	acyl-Coa dehydrogenase
TSC_c12760	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TSC_c12780	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
TSC_c12790	ENOG4108JPW	Aminotransferase
TSC_c12800	ENOG4107RUE	extracellular solute-binding protein family 1
TSC_c12810	ENOG4105D38	putrescine abc transporter
TSC_c12820	ENOG4105F38	ABC transporter, permease
TSC_c12830	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TSC_c12840	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TSC_c12850	ENOG4105C26	Dehydrogenase
TSC_c12860	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
TSC_c12870	ENOG4105D81	ABC transporter, permease
TSC_c12880	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TSC_c12890	ENOG4107TYH	extracellular solute-binding protein family 1
TSC_c12900	ENOG4108JPW	Aminotransferase
TSC_c12930	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
TSC_c12940	ENOG4105DSE	periplasmic solute binding protein
TSC_c12950	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
TSC_c12960	ENOG4107QIZ	NADH dehydrogenase
TSC_c12980	ENOG4108IEG	Formate dehydrogenase Alpha subunit
TSC_c12990	ENOG4105CH5	extracellular solute-binding protein, family 7
TSC_c13020	ENOG4105C1G	acyl-Coa dehydrogenase
TSC_c13030	ENOG4105BZJ	Electron transfer flavoprotein
TSC_c13040	ENOG4105C10	Electron transfer flavoprotein
TSC_c13060	ENOG4108HNZ	carboxyl transferase
TSC_c13070	ENOG4105E50	uracil-dna glycosylase
TSC_c13080	ENOG4105DCG	PHP domain protein
TSC_c13130	ENOG4105C88	aminopeptidase
TSC_c13140	ENOG4108FXY	Cys/Met metabolism PLP-dependent enzyme
TSC_c13150	ENOG41068KF	Universal stress protein
TSC_c13160	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
TSC_c13170	ENOG4105C8N	cysteinyl-tRNA synthetase
TSC_c13180	ENOG4105C1G	acyl-Coa dehydrogenase
TSC_c13190	ENOG4105CHU	acetyl-coa acetyltransferase
TSC_c13230	ENOG4108JA2	transcriptioN-repair coupling factor
TSC_c13250	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
TSC_c13260	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TSC_c13270	ENOG4107RJ7	Glycosyl transferase (Group 1
TSC_c13280	ENOG4107V8I	Glycosyl transferases group 1
TSC_c13310	ENOG4108UQV	Membrane
TSC_c13330	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TSC_c13340	ENOG4105DTQ	mandelate racemase muconate lactonizing
TSC_c13360	ENOG4107Y3Y	amidohydrolase
TSC_c13380	ENOG4105KHN	chorismate mutase
TSC_c13400	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TSC_c13410	ENOG4106H78	methyltransferase
TSC_c13440	ENOG4108IQK	o-acetylhomoserine
TSC_c13450	ENOG4105DWV	Homoserine O-trans-acetylase
TSC_c13460	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TSC_c13470	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TSC_c13490	ENOG4107RUY	(E1 component), alpha subunit
TSC_c13510	ENOG4105CIG	ABC transporter
TSC_c13600	ENOG4105CP7	Triose-phosphate isomerase
TSC_c13610	ENOG4105BZA	Phosphoglycerate kinase
TSC_c13620	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TSC_c13630	ENOG4107ZYJ	bioY protein
TSC_c13650	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TSC_c13660	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TSC_c13680	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TSC_c13790	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
TSC_c13820	ENOG4105KHC	sulfurtransferase
TSC_c13830	ENOG4105EJQ	L-serine dehydratase
TSC_c13840	ENOG4105WH1	Two component transcriptional regulator luxr family
TSC_c13850	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TSC_c13860	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TSC_c13870	ENOG4106GF2	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TSC_c13890	ENOG4105K5M	30s ribosomal protein S16
TSC_c13900	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TSC_c13910	ENOG4105CJW	magnesium transporter
TSC_c13930	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
TSC_c13950	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
TSC_c13960	ENOG4105D48	metallophosphoesterase
TSC_c13990	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TSC_c14010	ENOG4105CRQ	synthase (Component I)
TSC_c14020	ENOG4105C3R	Methionine synthase
TSC_c14030	ENOG4105DAP	Nicotinate phosphoribosyltransferase
TSC_c14040	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TSC_c14050	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TSC_c14060	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TSC_c14100	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TSC_c14110	ENOG4105X0R	protein from nitrogen regulatory protein P-II
TSC_c14120	ENOG41066UU	tRNA (Adenine-N1-)-methyltransferase
TSC_c14140	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TSC_c14180	ENOG4108UIC	UPF0340 protein
TSC_c14210	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
TSC_c14220	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TSC_c14250	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TSC_c14280	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
TSC_c14300	ENOG4105DBI	uridine monophosphokinase
TSC_c14340	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
TSC_c14350	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TSC_c14360	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TSC_c14380	ENOG4107T8J	thymidine kinase
TSC_c14400	ENOG41082DI	50s ribosomal protein l31
TSC_c14420	ENOG4108V6E	Cell division protein mraZ
TSC_c14430	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TSC_c14450	ENOG4105CJN	penicillin-binding protein
TSC_c14460	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
TSC_c14480	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TSC_c14490	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TSC_c14500	ENOG4105CNI	cell division protein FtsW
TSC_c14510	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TSC_c14520	ENOG4105DFU	Cell wall formation (By similarity)
TSC_c14530	ENOG4107QWW	Cell wall formation (By similarity)
TSC_c14550	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TSC_c14570	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TSC_c14580	ENOG4105WH1	Two component transcriptional regulator luxr family
TSC_c14610	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TSC_c14620	ENOG4105DB1	molybdopterin oxidoreductase
TSC_c14660	ENOG41066VF	YeeE YedE family protein
TSC_c14670	ENOG4105CMR	udp-glucose 4-epimerase
TSC_c14680	ENOG4108K28	Arsenite oxidase, large subunit
TSC_c14740	ENOG4105CHR	reductase
TSC_c14770	ENOG4105EHG	Permease protein
TSC_c14880	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TSC_c14900	ENOG4105D1F	ATP-binding protein
TSC_c14920	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TSC_c14940	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TSC_c14960	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TSC_c14970	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TSC_c14980	ENOG4105D78	K07001 NTE family protein
TSC_c15000	ENOG4105CDA	abc transporter atp-binding protein
TSC_c15030	ENOG4105E5Q	amino acid AbC transporter
TSC_c15040	ENOG4106PMH	Extracellular solute-binding protein family 3
TSC_c15060	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
TSC_c15070	ENOG4105C1A	potassium transporter peripheral membrane
TSC_c15080	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TSC_c15100	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
TSC_c15110	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
TSC_c15140	ENOG4105KJF	protein tyrosine phosphatase
TSC_c15150	ENOG4108XG2	Histidine kinase
TSC_c15170	ENOG4108JQC	penicillin-binding protein 1A
TSC_c15200	ENOG4105C3G	gtp-binding protein
TSC_c15210	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TSC_c15230	ENOG4108Z03	MAF-like protein
TSC_c15260	ENOG4105CJN	penicillin-binding protein
TSC_c15280	ENOG4108SJC	Membrane
TSC_c15320	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
TSC_c15330	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TSC_c15350	ENOG4105DBV	ornithine carbamoyltransferase
TSC_c15370	ENOG4105E0C	molybdate abc transporter
TSC_c15380	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TSC_c15400	ENOG4105CUT	histidyl-tRNA synthetase
TSC_c15410	ENOG4105C9M	aspartyl-trna synthetase
TSC_c15420	ENOG4107ZY0	Phenazine biosynthesis-like protein
TSC_c15430	ENOG4108X4Q	Hydrolase
TSC_c15450	ENOG4105E0F	Histidine kinase
TSC_c15460	ENOG4105ETX	regulatoR
TSC_c15480	ENOG4105C5S	asparaginyl-tRNA synthetase
TSC_c15490	ENOG4105CH5	extracellular solute-binding protein, family 7
TSC_c15510	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TSC_c15520	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
TSC_c15540	ENOG4107YCR	Transcriptional regulator, ARSR family
TSC_c15550	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
TSC_c15560	ENOG4105DR5	peptidase
TSC_c15570	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TSC_c15580	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
TSC_c15590	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TSC_c15610	ENOG4105DC7	peptidase M24
TSC_c15630	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
TSC_c15640	ENOG4105CVR	type I restriction-modification system
TSC_c15670	ENOG4105DZR	Type I site-specific deoxyribonuclease
TSC_c15690	ENOG4108Z4T	Peptidase M50
TSC_c15710	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TSC_c15830	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TSC_c15880	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TSC_c16120	ENOG4105VIZ	double-strand break repair protein
TSC_c16170	ENOG4105C4R	Atp-dependent dna helicase
TSC_c16190	ENOG4105EZM	VWA-like domain (DUF2201)
TSC_c16200	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
TSC_c16570	ENOG4108Z4T	Peptidase M50
TSC_c16650	ENOG4105CS9	pantothenic acid kinase
TSC_c16710	ENOG4105E2A	Dehydrogenase
TSC_c16720	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
TSC_c16730	ENOG4105C26	Dehydrogenase
TSC_c16790	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
TSC_c16800	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
TSC_c16830	ENOG41090RK	glycosyl transferase
TSC_c16930	ENOG4105VTR	Integrase
TSC_c16950	ENOG4105CE9	30S ribosomal protein S2
TSC_c16960	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TSC_c16970	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TSC_c16980	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TSC_c16990	ENOG4105KNE	Phosphatidate cytidylyltransferase
TSC_c17000	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TSC_c17010	ENOG4105DZP	Membrane-associated zinc metalloprotease
TSC_c17040	ENOG4105II7	pyrroline-5-carboxylate reductase
TSC_c17050	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TSC_c17060	ENOG4105MCT	stage V sporulation protein S
TSC_c17120	ENOG4105CYN	Serine protein kinase
TSC_c17130	ENOG4106AKX	UPF0229 protein
TSC_c17140	ENOG4105ED1	spovr family
TSC_c17150	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TSC_c17160	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
TSC_c17190	ENOG41082J7	Rhodanese domain protein
TSC_c17220	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
TSC_c17230	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TSC_c17240	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
TSC_c17250	ENOG4105C1Q	protoporphyrinogen oxidase
TSC_c17260	ENOG4106TD9	Diguanylate cyclase
TSC_c17310	ENOG4108QY0	Membrane
TSC_c17340	ENOG41062D9	Histidine kinase
TSC_c17350	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TSC_c17360	ENOG410841Q	phosphoesterase PA-phosphatase related protein
TSC_c17390	ENOG4107YEI	lmbE family
TSC_c17400	ENOG4105VG1	fes assembly suf system protein
TSC_c17500	ENOG4108IUE	nitrate reductase beta subunit
TSC_c17540	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
TSC_c17550	ENOG4108Z4U	Ferredoxin
TSC_c17570	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
TSC_c17580	ENOG4105F64	nitrite reductase
TSC_c17610	ENOG4108VKQ	nitriC oxide reductase
TSC_c17630	ENOG4105WD1	Membrane
TSC_c17670	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
TSC_c17720	ENOG4105CEP	NADH dehydrogenase
TSC_c17730	ENOG4105E33	succinate dehydrogenase
TSC_c17750	ENOG4108Z4U	Ferredoxin
TSC_c17770	ENOG4105KXX	peptidase s58 dmpa
TSC_c17790	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
TSC_c17800	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TSC_c17840	ENOG4105MS2	ribosomal subunit Interface protein
TSC_c17850	ENOG4105CAK	Cell division ATP-binding protein ftsE
TSC_c17860	ENOG4105CN1	protease
TSC_c17870	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TSC_c17880	ENOG4105E66	phosphoriboisomerase A
TSC_c17890	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TSC_c17910	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
TSC_c17920	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
TSC_c17930	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TSC_c17940	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TSC_c17960	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TSC_c17970	ENOG4105DIH	basic membrane
TSC_c17980	ENOG4108JQ9	ABC transporter
TSC_c18030	ENOG4105CQC	Prephenate dehydratase
TSC_c18040	ENOG4108KXV	response regulator
TSC_c18050	ENOG4105W87	Cbs domain
TSC_c18080	ENOG4105CNU	cell division protein FtsK
TSC_c18100	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TSC_c18110	ENOG4107ZQN	disulfide bond
TSC_c18120	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
TSC_c18130	ENOG4105CDY	transcriptional regulatory protein
TSC_c18140	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TSC_c18150	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TSC_c18210	ENOG4105C1G	acyl-Coa dehydrogenase
TSC_c18230	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TSC_c18240	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
TSC_c18340	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
TSC_c18360	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TSC_c18440	ENOG41080QG	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TSC_c18470	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TSC_c18510	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
TSC_c18520	ENOG4108HMX	isocitrate dehydrogenase (NADP)
TSC_c18590	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
TSC_c18630	ENOG4105KA0	thioesterase Superfamily protein
TSC_c18650	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TSC_c18660	ENOG4105C75	arginyL-tRNA synthetase
TSC_c18670	ENOG4105C0H	protease
TSC_c18700	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TSC_c18710	ENOG4108JIF	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
TSC_c18720	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TSC_c18730	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TSC_c18750	ENOG4105CBT	Fructose-1,6-bisphosphatase
TSC_c18800	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
TSC_c18810	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
TSC_c18910	ENOG4105F8V	Hydrolase, tatD family
TSC_c18920	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TSC_c18940	ENOG4105C5S	asparaginyl-tRNA synthetase
TSC_c18960	ENOG4105E33	succinate dehydrogenase
TSC_c19010	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TSC_c19030	ENOG4105CIG	ABC transporter
TSC_c19070	ENOG4105CEY	Amp-dependent synthetase and ligase
TSC_c19080	ENOG4107QI6	Cysteine desulfurase
TSC_c19090	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
TSC_c19100	ENOG4105CC5	ABC transporter
TSC_c19110	ENOG4105DIK	(ABC) transporter
TSC_c19130	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
TSC_c19140	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TSC_c19180	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
TSC_c19200	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
TSC_c19210	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
TSC_c19260	ENOG4105CT4	transporter
TSC_c19280	ENOG4105CPF	Cell wall formation (By similarity)
TSC_c19290	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TSC_c19300	ENOG4107UH2	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TSC_c19310	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TSC_c19320	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
TSC_c19330	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
TSC_c19340	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TSC_c19360	ENOG41067KJ	GYD family
TSC_c19390	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TSC_c19400	ENOG4107QX3	carboxylase
TSC_c19410	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
TSC_c19470	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TSC_c19500	ENOG4105CG3	alpha amylase, catalytic region
TSC_c19530	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
TSC_c19550	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
TSC_c19560	ENOG4105D6E	homoserine dehydrogenase
TSC_c19640	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TSC_c19650	ENOG4106C07	ThiamineS Protein
TSC_c19660	ENOG4105DGU	Histone deacetylase
TSC_c19670	ENOG41080XP	Cbs domain
TSC_c19690	ENOG4105C3U	ABC transporter
TSC_c19700	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TSC_c19720	ENOG4107QRA	Extracellular solute-binding protein, family 5
TSC_c19730	ENOG4105CB2	alcohol dehydrogenase
TSC_c19740	ENOG4105CAY	ferredoxin--nadp reductase
TSC_c19820	ENOG4108Z7R	Chaperone CsaA
TSC_c19830	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TSC_c19840	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TSC_c19920	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TSC_c19930	ENOG4105BZU	Histidine kinase
TSC_c19970	ENOG4105DJV	ribulose-phosphate 3-epimerase
TSC_c19990	ENOG4105CV1	Transketolase (EC 2.2.1.1)
TSC_c20030	ENOG4105C1J	atp-dependent rna helicase
TSC_c20040	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TSC_c20090	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
TSC_c20110	ENOG4105E3H	phosphoglycerate mutase
TSC_c20120	ENOG4105SFS	phosphoesterase RecJ domain protein
TSC_c20150	ENOG4105CHR	reductase
TSC_c20160	ENOG4105E09	nadh pyrophosphatase
TSC_c20180	ENOG4105CAT	Cytidine monophosphate kinase
TSC_c20190	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TSC_c20210	ENOG4105DG6	mannose-6-phosphate isomerase
TSC_c20230	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
TSC_c20250	ENOG4105K70	DNA-binding protein
TSC_c20260	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TSC_c20270	ENOG4105CFG	Acts as a chaperone (By similarity)
TSC_c20280	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TSC_c20290	ENOG4105DVC	DnaJ domain protein
TSC_c20300	ENOG4108FYC	transcriptional regulator MERR family
TSC_c20310	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TSC_c20370	ENOG4108ZVP	Domain of unknown function (DUF1931)
TSC_c20390	ENOG4105NCW	Trka-c domain protein
TSC_c20400	ENOG4107S91	Sodium hydrogen exchanger
TSC_c20460	ENOG4105CDU	Replicative dna helicase
TSC_c20490	ENOG4105CBC	glutamate synthase
TSC_c20500	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TSC_c20510	ENOG4107QR9	Iron-sulfur cluster binding protein
TSC_c20520	ENOG4107QR9	Iron-sulfur cluster binding protein
TSC_c20540	ENOG4105D78	K07001 NTE family protein
TSC_c20550	ENOG4105D9P	serine threonine protein kinase
TSC_c20570	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TSC_c20590	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
TSC_c20630	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TSC_c20650	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TSC_c20710	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TSC_c20720	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
TSC_c20730	ENOG4105D49	3-dehydroquinate synthase
TSC_c20750	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TSC_c20770	ENOG41084ZW	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TSC_c20800	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TSC_c20830	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
TSC_c20840	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TSC_c20850	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TSC_c20870	ENOG4108AH5	Binds directly to 16S ribosomal RNA (By similarity)
TSC_c20890	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TSC_c20920	ENOG4105KWW	Biogenesis protein
TSC_c20930	ENOG4107QX9	Thiol disulfide interChange protein
TSC_c20940	ENOG4105DA4	cytochrome c-type biogenesis protein
TSC_c20950	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
TSC_c20960	ENOG41060IM	Heme exporter protein
TSC_c20970	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
TSC_c20980	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
TSC_c20990	ENOG4107QIV	Cytochrome c biogenesis protein
TSC_c21010	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
TSC_c21020	ENOG4107S7U	Sulfide dehydrogenase
TSC_c21050	ENOG4105QN4	diheme cytochrome
TSC_c21060	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
TSC_c21070	ENOG4105CGH	5'-nucleotidase
TSC_c21080	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
TSC_c21090	ENOG4105QN4	diheme cytochrome
TSC_c21130	ENOG41067HZ	cytochrome C, class I
TSC_c21140	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TSC_c21180	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TSC_c21190	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TSC_c21200	ENOG4108UJD	30S ribosomal protein S9
TSC_c21210	ENOG4105C4R	Atp-dependent dna helicase
TSC_c21250	ENOG4105EB3	Histidine kinase
TSC_c21260	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TSC_c21270	ENOG4105D9P	serine threonine protein kinase
TSC_c21280	ENOG4108ZF3	Phosphatase
TSC_c21310	ENOG4105D52	delta-aminolevulinic acid dehydratase
TSC_c21320	ENOG41080DW	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
TSC_c21330	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TSC_c21380	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TSC_c21390	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
TSC_c21400	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TSC_c21450	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
TSC_c21460	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
TSC_c21480	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TSC_c21510	ENOG4107YU2	histidine triad (hIT) protein
TSC_c21520	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TSC_c21540	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
TSC_c21550	ENOG4105ECY	inositol monophosphatase
TSC_c21570	ENOG4108UKM	mov34 mpn pad-1 family protein
TSC_c21580	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TSC_c21590	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TSC_c21600	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TSC_c21610	ENOG4108UT2	hemolysin iii
TSC_c21630	ENOG41062D9	Histidine kinase
TSC_c21700	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TSC_c21720	ENOG4108Z8I	decarboxylase
TSC_c21730	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TSC_c21760	ENOG4105C83	adenylosuccinate lyase
TSC_c21790	ENOG4105C8V	SAICAR synthetase
TSC_c21810	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
TSC_c21830	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
TSC_c21860	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TSC_c21870	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TSC_c21880	ENOG4105KDM	Diguanylate cyclase with gaf sensor
TSC_c21890	ENOG41081FY	multiple antibiotic resistance (MarC)-related
TSC_c21900	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
TSC_c21910	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TSC_c21920	ENOG41079SJ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
TSC_c21930	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
TSC_c21950	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
TSC_c21960	ENOG4105JFG	SpoIID LytB domain protein
TSC_c21970	ENOG41074B2	UPF0747 protein
TSC_c21990	ENOG4105E63	Pfam:DUF178
TSC_c22050	ENOG4105D82	Glutamate dehydrogenase
TSC_c22060	ENOG4105D82	Glutamate dehydrogenase
TSC_c22070	ENOG4105EAH	synthase
TSC_c22140	ENOG4108UZ3	Transporter
TSC_c22160	ENOG4108ZT0	50S ribosomal protein l17
TSC_c22170	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TSC_c22180	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TSC_c22190	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TSC_c22200	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TSC_c22210	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TSC_c22230	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TSC_c22240	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TSC_c22250	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TSC_c22260	ENOG410856V	50S ribosomal protein L30
TSC_c22270	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TSC_c22280	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TSC_c22320	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TSC_c22330	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TSC_c22340	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TSC_c22360	ENOG4108CHD	50s ribosomal protein l29
TSC_c22370	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TSC_c22380	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TSC_c22390	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TSC_c22400	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TSC_c22410	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TSC_c22420	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TSC_c22430	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TSC_c22440	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TSC_c22450	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TSC_c22460	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TSC_c22470	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TSC_c22480	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TSC_c22490	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TSC_c22510	ENOG4105D60	lipoprotein releasing system transmembrane protein
TSC_c22540	ENOG4105DP4	dak2 domain fusion protein ylov
TSC_c22560	ENOG4105DCF	alanine dehydrogenase
TSC_c22570	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TSC_c22580	ENOG41060WC	Enoyl-CoA hydratase
TSC_c22590	ENOG4105FE9	pseudouridine synthase
TSC_c22600	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TSC_c22620	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TSC_c22630	ENOG4107QYG	anthranilate phosphoribosyltransferase
TSC_c22640	ENOG4105DDQ	anthranilate synthase
TSC_c22650	ENOG4105CRQ	synthase (Component I)
TSC_c22660	ENOG4105C26	Dehydrogenase
TSC_c22670	ENOG41062BK	proline dehydrogenase
TSC_c22680	ENOG4107XBN	GntR Family Transcriptional Regulator
TSC_c22710	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TSC_c22720	ENOG4105XEZ	This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands and protects the DNA from cleavage by the
TSC_c22740	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TSC_c22750	ENOG4105CQ7	ATP-dependent helicase
TSC_c22770	ENOG4105E2A	Dehydrogenase
TSC_c22870	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
TSC_c22880	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
TSC_c22890	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TSC_c22900	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TSC_c22910	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TSC_c22930	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
TSC_c22940	ENOG410850P	UPF0102 protein
TSC_c22960	ENOG4105C3M	thioredoxin reductase
TSC_c22970	ENOG4105CHR	reductase
TSC_c22990	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TSC_c23010	ENOG4105I08	Pseudouridine synthase
TSC_c23020	ENOG41073R8	VanW family
TSC_c23030	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TSC_c23040	ENOG4105CYC	Transferase
TSC_c23050	ENOG4105DCF	alanine dehydrogenase
TSC_c23080	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TSC_c23090	ENOG4105C87	Aminotransferase class I and II
TSC_c23100	ENOG4108SHS	Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent (By similarity)
TSC_c23120	ENOG4105C5X	domain protein
TSC_c23140	ENOG4108Z9K	Osmotically inducible protein
TSC_c23160	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TSC_c23170	ENOG4107QKW	extracellular solute-binding protein family 1
TSC_c23190	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TSC_c23200	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TSC_c23210	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TSC_c23230	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
TSC_c23240	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
TSC_c23260	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TSC_c23290	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
TSC_c23300	ENOG4105BZU	Histidine kinase
TSC_c23310	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TSC_c23320	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
TSC_c23330	ENOG4108URH	decarboxylase
TSC_c23340	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TSC_c23380	ENOG4105D56	permease protein
TSC_c23390	ENOG4105EG2	ABC transporter, permease
TSC_c23400	ENOG4107R28	alpha amylase, catalytic region
TSC_c23420	ENOG4105C98	muts2 protein
TSC_c23430	ENOG4105C98	muts2 protein
TSC_c23470	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TSC_c23480	ENOG4105UIB	(ABC) transporter
TSC_c23510	ENOG4105MA4	psp1 domain protein
TSC_c23520	ENOG4107QRG	dna polymerase iii
TSC_c23590	ENOG4105C22	threonyL-tRNA synthetase
TSC_c23620	ENOG4108IJG	ABC transporter substrate-binding protein
TSC_c23640	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
TSC_c23660	ENOG4107EUI	c reductase, iron-sulfur
TSC_c23670	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TSC_c23680	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TSC_c23830	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
TSC_c23860	ENOG4105U0R	haloacid dehalogenase-like hydrolase
TSC_c23890	ENOG41081QV	Universal stress protein
TSC_c23900	ENOG4105C2N	RNA methyltransferase TrmH family group 3
TSC_c23910	ENOG4108KB0	deacetylase
TSC_c23930	ENOG4105DKQ	ROK family
TSC_c24010	ENOG4105EUJ	GTP cyclohydrolase i
TSC_c24030	ENOG41062IR	nudix hydrolase
TSC_c24050	ENOG4105CI3	gtp-binding protein typa
TSC_c24110	ENOG4105D1H	recombination factor protein RarA
TSC_c24140	ENOG4105DRS	transport system, permease
TSC_c24150	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
TSC_c24160	ENOG4105CJ1	ABC, transporter
TSC_c24190	ENOG4105C7S	Dehydrogenase
TSC_c24200	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TSC_c24230	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TSC_c24240	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TSC_c24260	ENOG4105C3M	thioredoxin reductase
TSC_c24320	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TSC_c24330	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TSC_c24350	ENOG4105C8B	TIGR00159 family
TSC_c24360	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
TSC_c24440	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
TSC_c24450	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TSC_c24460	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TSC_c24470	ENOG4105C02	permease
TSC_c24490	ENOG4106633	50S ribosomal protein l28
TSC_c24500	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TSC_c24520	ENOG4105CHM	Aminotransferase
TSC_c24540	ENOG4105CBD	Diacylglycerol kinase
TSC_c24570	ENOG4105DGU	Histone deacetylase
TSC_c24580	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
TSC_c24590	ENOG4105CB5	ATP-dependent DNA helicase recG
TSC_c24600	ENOG4105BZU	Histidine kinase
TSC_c24610	ENOG4108YZA	Nitrogen regulatory protein pii
TSC_c24630	ENOG4108ZAF	Molybdopterin
TSC_c24660	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TSC_c24670	ENOG4105C1G	acyl-Coa dehydrogenase
TSC_c24690	ENOG4105C8T	Leucyl-tRNA synthetase
TSC_c24710	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TSC_c24720	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TSC_c24750	ENOG4108WBT	adenosyltransferase
TSC_c24770	ENOG4108IUW	ABC transporter
TSC_c24780	ENOG4108SDH	ABC, transporter
TSC_c24830	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
TSC_c24840	ENOG4105CHW	UPF0052 protein
TSC_c24870	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TSC_c24880	ENOG4105C25	Primosomal protein n'
TSC_c24910	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TSC_c24920	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
TSC_c24940	ENOG4105CTQ	phosphohexokinase
TSC_c24970	ENOG4105F0N	pyrophosphate phospho-hydrolase
TSC_c24980	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TSC_c25030	ENOG4105FA0	parb-like partition protein
TSC_c25040	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
TSC_c25050	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TSC_c25060	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TSC_p800060	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
TSC_p800090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TSC_p800120	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)